UMASS/AMHERST ^ 315Dt>bDD552757S F^^ J*-'' :.w :''-Am. ^^ \ '^v 5t^>¥^ L LIBRARY OF THE MASSACHUSETTS AGRICULTURAL COLLEGE souRCE__ilDJJ_^$_e._..-^la.'na2i. SF 805 N48 This book may be kept out TWO WEEKS only, and is subject to a fine of TWO CENTS a day thereafter. It will be due on the day indicated below. ^ Digitized by the Internet Arciiive in 2010 witii funding from Boston Library Consortium IVIember Libraries littp://www.arcliive.org/details/reportontexascatOOnewy REPORT OP THE N. I. STATE CATTLE COMIISSIOIEES, IN CONNECTION WITH THE SPECIAL REPORT OF THE METROPOLiTM BOARD OF liEALTB, TEXAS CATTLE DISEASE. REPORT OF THE NEW YORK STATE CATTLE COMMISSIONERS, FOR THE YEAR 1868, To the Honorable the Legislature of the State of New York :* The Board of Commissioners, organized under "An act to prevent the introduction and spread of the disease known as the Rinderpest, and for the protection of the flocks and herds of sheep and cattle in this State from destruction by this and other infec- tious diseases," passed April 20, 1866 (chap. 740), and amended April 19, 1867 (chap. 453), respectfully min REPORT That the disease known as Rinderpest has not, since the date of their report for 1867, reappeared in the British Isles, or in any of those countries in Europe from which cattle are usually brought to the United States; and it is believed that, with the knowledge we now have of the disease itself, and of its treatment, its ravages would be speedily checked, should it, by any accident enter our State. The report of the Hon. A. B. Conger, of the State Agricultural Society, on the " Statistics, pathology and treatment of the epizootic disease known as the Rinderpest," is an exceedingly valuable con- tribution to veterinary science, and its publication in the Transac- tions of the Society, will very widely extend the knowledge of epizootic diseases, and their treatment, among the stock owners of New York State. With the banishment of Rinderpest to its native steppes in South- ern Russia and Hungary, all fears in regard to the safety of cattle in this country passed away, and a sense of security was felt by all engaged in breeding, feeding and handling stock. IAg.] 60 946 Annual Report of New TorjT. FIRST APPEARANCE OF TEXAS CATTLE DISEASE. About the 10th of June last, however, a disease appeared at Cairo, the southern terminus of the Illinois Central railroad, at the junction of the Ohio with the Mississippi river, where large num- bers of cattle from Texas were being landed, and shipped thence, by rail, to the interior of Illinois and Indiana. This disease was soon recognized as " Spanish fever," so called in the Gulf States; but better known in more Northern States as the "Texas cattle disease" — a scourge that had repeatedly crossed the Texan border and swept oif immense numbers of cattle in Kansas and Missouri, previous to the late civil war, causing the enactment of prohibitory laws in those States, relative to the intro- duction of Texas cattle. From Cairo the disease was conveyed along the railway lines into the interior of Illinois and Indiana, reaching the little town of To'lono, at the crossing of the Illinois Central and Toledo and Wabash railroads, about the 20th of July, and speedily sweeping away almost every native animal of the bovine race in that neigh- borhood — two hundred and thirty-five cows having died between that date and the first of August. ITS RAVAGES IN ILLINOIS. From fifteen thousand to eighteen thousand head of Texas cattle had been landed at Tolono, resulting in the estimated loss of five thousand head of native cattle in the county of Champaign alone,* while multitudes were dying in other parts of that State and Indiana; and stock destined to Eastern markets had become diseased to such an extent, by the 5th of August, as to endanger the lives of meat-consumers in the cities that draw their supplies of beef from the Western States. METROPOLITAN BOARD OF HEALTH. By the 8th of August, it became apparent to the officers of the Metropolitan Board of Health in New York city, that the alarming increase of obstinate and fatal diarrhoeas in the Metropolitan dis- trict, was caused by the use of diseased meats, and measures were instantly taken to arrest the evil. The action of the Board, wise, energetic and far seeing, not only averted the calamity that threat- ened the city, but far beyond all this, by the rigid investigation it conducted in resrard to the nature and character of the disease, * See page 6, " Report of Delegates of Board of Agriculture, Province of Ontario." State Agricultural Society. 947 large contributions have been made to sanitary science, generally, and certain great laws of hygiene established for the future. ACTION OF THE STATE EXECUTIVE. His Excellency Governor Fenton, after corresponding with the Governors of New Jersey and Pennsylvania, who cooperated with him in his efforts to check the progress of this fearful plague, summoned the Einderpest Commission, as it was called, to meet hira in Albany on the 17th of August, at the Executive chamber. ACTION OF THE STATE COMMISSION. In obedience to the summons, the Commission met, and received from His Excellency all papers and correspondence that had come to him on the subject, with instructions to carry out the provisons of the acts of the Legislature establishing the Commission. On the 18th, Prof. Jacob W. Mosher, of the Albany Medical College, was placed in charge of the Albany district as Assistant Commissioner, with Mr. John Phillips as his assistant, at the drove yards; Dr. Moreau Morris, Sanitary Inspector of the Metropolitan Board of Health, was appointed Assistant Commissioner for the Metropolitan district, with instructions and authority to act as such along all the lines of travel leading to the city; and Dr. William Manlius Smith of Onondaga, was dispatched to Suspension Bridge, to prevent the introduction of diseased cattle through the province of Ontario, via the Great Western railway from Detroit and the Western States. The city of Buffalo being cared for by its Board of Health, the stock yards were, temporarily, placed under its health officer, and the stations of Dunkirk and Jamestown provided for until they could be visited by the Commissioners. A brief code of instructions, regulating the inspection of cattle at the stock yards, the transit of cattle through the State, the dis- infection of cars, and quarantine of diseased animals, was drawn up by the Commission, and published generally throughout the State within the next three days. (A copy marked "A" is hereto appended.) INSPECTION OF THE DEPOT, ETC., BY THE COMMISSIONERS. On the 19th of August, the Commissioners separated, and made, each, a rapid survey of his own district, Commissioner Allen taking the Western, Gould the Eastern, and Patrick the Central district of the State, while Dr. John Swinburne, Health Officer of the Port of New York, was instructed by His Excellency to join 948 Annual Report of New York the Commissioners in making a tour of the State, that his knowledge of the principles of quarantine might be made available in carry- ing out the regulations already published. THE STOCK YARDS AT CAMPVILLE. At Campville, on the Erie road, the disease had first appeared on the 9th of August, some eighteen or twenty head of Western cattle, taken from the cars on the previous day, having died within a few hours. They were buried in shallow trenches near the river, and into these same trenches, shortly after, were thrown the mangled remains of a large number of cattle, the debris of a railroad smash- up, some distance east of Campville. Only a few inches of soil was thrown into the trenches, not even covering the animals from sight, and the weather being extremely hot, such a stench arose from that mass of corruption as threatened a pestilence, when Messrs. Swinburne and Patrick reached there on the morning of the 21st of August. They were soon after joined by Dr. J. G. Orton, of Binghamton, who had been previously directed by Gov. Fenton to visit that station, and who was imme- diately placed in charge of the district as Assistant Commissioner, with E. Van Tuyl as his assistant, at the Campville stock yards. Under Dr. Orton's directions, the trenches were promptly covered with lime, and then with a heavy covering of earth, well sprinkled with carbolic acid, as found in the heavy oil of coal tar. All the yards, lanes and platforms about the premises were thoroughly dis- infected by the use of the heavy oil. . The result of this process was almost instantaneous and perfect; no offensive effluvia afterwards arose, and no case of disease has since appeared. ELMIRA. At Elmira, arrangements were made with Drs. Way, Squires and Chubbuck, city physicians, to act temporarily in case the disease should appear at that place, and Mr. G. E. Carpenter was appointed Assistant Commissioner for the district. As no case of Texas cattle disease has shown itself in that neighborhood, these gentle- men have not been called into service. MEETING OF THE COMMISSIONERS AT BUFFALO. By the night of the 22d (Saturday), the Commissioners were all gathered at Buffalo, Dr. Swinburne being with them. The mayor of the city. Gen. W. F. Eogers, the Board of Health, the railroad State Agricultural Society, 949 officers, alnd many prominent citizens of Bufialo, took an active interest in the business of the Commission, and by the 24th (Mon- day) a system of inspections, quarantine and disinfection had been perfected and put under the control of Dr. E. E. Mackay, Health Officer of the city, who was appointed Assistant Commissioner, with D. M. Josslyn as his assistant, at the extensive stock yards of the Central railroad. As Buffiilo is the principal gateway through which cattle enter the State from the West, and vast numbers are being landed there continual Ij'-, rendering it necessary that a very rigid control should be exercised at that point. Commissioner Allen was specially charged with the supervision of that important depot. SUSPENSION BRIDGE. The Canadian authorities having, by an order of his Excellency the Governor-General, in Council, prohibited the introduction of horned cattle from the United States into the Provinces of Quebec and Ontario, all danger of infection from the transportation of Western cattle over the Great Western railway, ceased, and Dr. Wm. M. Smith was withdrawn from Suspension Bridge, to take the place of medical adviser to the Commission, Dr. Swinburne being compelled, by his official duties as Health Officer of the Port, to return to New York. DUNKIRK. On the 25th, the Commission proceeded to Dunkirk, the western terminus of the Erie road, and there established such quarantine, inspection, and other regulations as appeared needful, appointing A. H. Abell, Esq. Assistant Commissioner, with Dr. Benedict as medical adviser, if his services should at any time be deemed necessary. ERIE. As no system of inspections, quarantine, or other regulations in regard to diseased cattle had yet been promulgated in Pennsyl- vania, at the request of the Lake Shore railroad officers, the Com- missioners extended their observations as far west as Erie, where they had an interview with Mr. Luce, the transportation agent of the Lake Shore road at that place. After a full understanding of the objects of the Commission, and an examination of the instruc- tions and regulations issued to its own inspectors, Mr. Luce decided to adopt, as far as practicable, the same system at Erie; thus prac- *. 950 Annual Report of New York tically extending our own quarantine regulations some twenty-five miles bej^ond the limits of our own State. JAMESTOWN. As the Atlantic and Great Western railway, connecting with the Erie railway at Salamanca, aflfords a fourth gateway for cattle to enter the State from the West, the Commission visited Jamestown, and there established the same system of inspections, quarantine, etc., as at Dunkirk, and appointed Sardius Stewart, Esq., Assistant Commissioner for the Jamestown district. Having thus established a system of inspection at every point where Western cattle enter the State, the Commission returned to Buffalo on the evening of the 27th of August, where they found several cattle in hospital yards, and had an opportunity to study the disease itself more fully than heretofore; for up to that time very few facts had been gathered as to its real nature. THEORIES IN REGARD TO THE DISEASE. Great numbers of Western drovers and stock dealers were exam- ined as to their knowledge of its character and efiects, resulting in the enunciation of a multitude of theories, prominent among which were: 1. That no Texas cattle had ever been known to die, or be affected with the disease themselves, but were universally regarded as sound and healthy. 2. That by some mysterious agency, these healthy Texas cattle had, at various times within the last few years, infected the native cattle of the Western States with a fatal disease. 3. That native cattle, though sick and dying of the disease, could not impart it to other cattle. 4. That the meat of diseased animals had never been known to produce any ill results to the consumer, and might, therefore, be regarded as healthy food. 5. That with the first frosts of autumn, the disease entirely dis- appeared, and no infection could be conveyed thereafter by Texas cattle. The facts, however, that came under the observation of the Com- missioners, led them to discard these theories, though without, then, arriving at conclusions entirely satisfactory to themselves on the subject; and on the 28th of August they adjourned, to meet again in New York city, on the 2d of September, there to make more thorouofh and accurate investigations. State Agricultural Society. 951 MEETING OF THE COMMISSIONERS IN NEW YORK CITY. Accordingly, on the 2d of September, Messrs. Patrick and Gould, with Dr. William Manlius Smith, met in New York, and were joined by Dr. Swinburne, Health Officer of the Port, Dr. Harris, Eegistrar of Vital Statistics of the Metropolitan Board of Health, and Dr. Moreau Morris, its Sanitary Inspector and Assistant Com- missioner for the district. In consequence of the large number of cattle arriving at Buflalo, it was not deemed safe for Mr. Allen to leave that most exposed position, at that time, and the other mem- bers of the Commission were obliged to go on without him. Under the guidance of the officers of the Board of Health, a thorough survey of the whole field of operations w^as instituted, extending beyond the city limits and across the Hudson to the stock yards and abattoirs on the Jersey side, which furnish meats to the New York markets. The " bone boiling" and "rendering" establishments were visited, to follow up condemned meats, and ascertain the final disposition made of them, as well as to become familiar with the various processes of disinfection in use at those places, where carcases of dead animals, in every stage of putref-ic- tion, were gathered from every part of the city. METROPOLITAN BOARD OF HEALTH INSTITUTES INVESTIGATIONS. Autopsies of animals dying of the Texas disease, were made by the officers of the Board of Health, at the drove yards of the Messrs. Allerton, and the results of these examinations recorded. A careful analysis of the various tissues, fluids and viscera of the animals was conducted by Prof. Chandler, of the School of Mines, Columbia College, Chemist of the Board, while the same st^-uctures were subjected to the scrutiny of Prof. Stiles, of Brooklyn, Micro- scopist of the Board. Bringing his skill and large experience to the work, Prof. Stiles soon unmasked the mysterious and active agent in this disease, revealing not only its perfect outline and form, under the microscope, to every eye, but, with equal distinct- ness, exhibiting the mode of its attack upon the blood discs, and the entire destruction of the blood that resulted from it. One of the most brilliant discoveries in medical science, but not more brilliant than useful. RESULTS OF OBSERVATIONS. As the result of their observations in New York, the Commis- sion drew up the paper marked " B" (appended hereto), and caused it to be published in the leading papers throughout the State. 952 Annual Report of New York Notwithstanding the utmost caution and watchfulness at Buffalo, and other places of inspection, diseased cattle often reached New York city, until quite late in the season, and the Commissioners were frequently called to look at cattle in different localities, and affected with various ailments, but which, in the excited state of the public mind, were supposed to be cases of real Texas disease. WESTERN COMMISSIONERS SENT TO NEW YORK. As was expected, the inspection and quarantine regulations estab- lished at Buffalo, and other railway depots, created great consterna- tion in the Western cattle dealing States, and caused His Excellency Governor Oglesby, of Illinois, to appoint a special commission with instructions to visit New York, for the purpose of conferring with Gevernor Fenton and the New York Commission, as to the best means of regulating the shipment of cattle to Eastern markets, so as to embarrass the trade as little as possible, while protecting the health of our citizens and guarding their herds from infection. (See paper marked " C," hereto appended.) An examination of the workings of the system adopted in this State, proved satisfactory to the Illinois Commissioners, and a request was made by them, that a call should be issued by the Governor of the State of New York, for a convention of commis- sioners from all the States interested in breeding, feeding, handling and shipping cattle, as well as from the Eastern consuming States, where cattle are marketed. CALL FOR A CONVENTION OF CATTLE COMMISSIONERS. In this request Illinois was joined by other Western States and Canada; resulting in the issue of a circular from the Executive Chamber in Albany, calling such convention to meet at the city of Springfield, Illinois, on the 1st day of December, 1868. (See paper marked " E.") As the subjects to be discussed in that Convention involved ques- tions of vital importance to the citizens of this State, it was essential that this Commission should be thoroughly prepared to meet them understandingly, and be able to bring facts before the convention, in opposition to the interested statements of dealers in Texas cattle, and the numberless theories set afloat in regard to the character and effects of the disease, by persons who had never thoroughly inves- tigated the subject. State Agricultural Society. 953 NEW YORK STATE COMMISSIONERS AND METROPOLITAN BOARD OF HEALTH. Accordingly, after having met and conferred with the commis- sioners of the Province of Ontario, who had but just returned from an extended tour of observation in the West, the New York Com- missioners assembled at the rooms of the Metropolitan Board of Health, in the city of New York, on the 2d day of November, and were permitted to avail themselves of the results derived from all the scientific investigations that had been going on since the 8th of August, as well as all the data gathered by Dr. Harris, the Eegis- trar of the Board, in the course of his widely extended correspond- dence, and the mass of facts gathered by Assistant-Commissioner Morris and his associate inspectors of the Board of Health, during the prevalence of the disease. Every stock yard, abattoir, slaughter house, rendering and bone- boiling establishment of the Metropolitan district, was made the subject of investigation, and all classes of disease affecting rumi- nants (and to some extent swine), came under the observation of the Commission, revealing such an amount of reckless barbarity towards animals, and of criminal indifference to the public health, on the part of many who furnish meat to consumers, that one almost wonders how the city has escaped a pestilence. It is to be hoped that some of these terrible nuisances will soon be abated by law, and that all animals for slaughter Avill be taken to the great abattoirs of Communipaw, East Forty-fourth street, and the like, where the meat can be inspected by a proper officer, and everything condemned, be conveyed speedily to such rendering dock as that of West Thirty-eighth street, where steam and car- bolic acid effectually destroy all offensive odors. DR. MORRIS TO REPRESENT THE METROPOLITAN BOARD OF HEALTH AT SPRINGFIELD CONVENTION. As it was of much importance that some competent medical gentleman, who had been personally acquainted with the disease as it developed in New York, should be present at the Convention in Springfield, the Board of Health very kindly authorized its Sanitary Inspector (and our Assistant Commissioner), Dr. Moreaii Morris, who, more perhaps than any other individual in the city, had come in contact with infected and diseased cattle, to accompany the Slate Commissioners to the Convention. 954 Annual Report of New York TEXAS DISEASE IN ORANGE COUNTY. A question of great interest in connection with the spread of this infection, had been settled, by facts, only the week previous to the meeting of the Commission in New York. On the 20th of October, Commissioner Gould had been called to Hamptonburgh, in the milk district of Orange county, to ascertain the cause of a number of sudden deaths amono- cattle in that neighborhood. Dr. Morris was eventually summoned from New York, and on the 24th October, with Mr. Gould and Dr. Montfort, Assistant Commissioner, made post mortem examinations of two heifers, found dead on that day, and these were followed by the post mortem examination of a cow on the 27th, by Dr. Montfort. From all the facts elicited during these investigations, and from the autopsies of the animals, not a doubt was left on the minds of these gentlemen that they had died of genuine Texas cattle disease; and further, that this disease had been introduced into that neighborhood by a herd of native cows brought from Painesville, Ohio, on the Lake Shore railroad, over which large numbers of Texas cattle had been passing. (Com- missioner Gould's instructions to farmers, marked " E," are hereto annexed.) As it had been almost universally assumed in the West, that Texas cattle., only, could communicate the disease, an important question was settled at Hamptonburgh. AUTOPSIES OF TEXAS BULLOCKS AT BUFFALO. Again: It had been announced by stock dealers as an undeniable fact; that, although Texas cattle might give the disease to native cattle, they were never affected by it themselves. Yet at Biifialo, on the 24th of November, the Commissioners found two Texas steers (taken on the previous day from a herd directly from Kansas) in a dying condition; and, on being slaughtered, presented every characteristic feature of the genuine Texas cattle disease in its most intensified form; and this, too, in very cold weather, after nearly two months of frost — establishing beyond all cavil the fact, that Texas cattle may die of the disease, and that, in freezing cold weather. A TEXAS HERD AT LAFAYETTE, INDIANA. While on their way to Springfield, the Commissioners sought information from all sources; and at Lafayette, Indiana, spent a day in the slaughtering establishment of Sample & Son, where a herd of one hundred and forty-two Texas cattle were being slaughtered State Agricultural Society. 955 for packing. These animals appeared to he, in perfect health, pre- senting no external symptoms of any disease, and the meat, except in a single instance, appeared to be of good quality; yet the viscera of large numbers of these animals, taken indiscriminately from the herd, exhibited in every instance the unmistakable scars which that disease invariably leaves upon the coats of the stomach. So evident did it appear to the Commission, that Texas cattle, as a class, were all, more or less, at some time, affected by this peculiar disease, which invariably left upon the coats of the stomach an ineffaceable and characteristic mark, that Texas cattle dealers in Springfield were permitted to select one of the best Texas bullocks, from the best Texas herd of the season, and have it slaughtered, to test the question. EXAMINATION OF THE STOMACHS OF A TEXAS STEER AND NATIVE COW, AT SPRINGFIELD, ILL. On the morning of the 1st of December, in the presence of a large number of gentlemen of the Convention, and cattle men gen- erally, the selected animal was slaughtered, and presented such jialpable evidences of former disease, as to convince the most skep- tical. To meet the assertion, " that all animals grazed on Western prairies, presented the same appearance of scars upon the stomach," a fat native cow was knocked down, and, on being opened, the stomach exhibited a perfectly smooth, clean and healthy appear- ance, entirely different from that of the Texas animal lying by its side. The record of disease written upon the viscera of the Texas animals, so distinct and perfect as to be seen of all men, had much influence in settling the opinions of Commissioners who had already assembled from most of the States; so that, when the Conven- tion organized, much useless debate upon exploded theories was avoided. MEETING OF THE CONVENTION. The convention met in the Hall of Representatives at 12 m., on Tuesday, the 1st day of December, and proceeded to business. Hon. Lewis F. Allen, of the New York Commission, was chosen President of the Convention, which continued its sitting until Thurs- day, the 3d, when it adjourned. As a very full copy of its proceedings are published under the direction of His Excellency Governor Oglesby, it will not be neces- sary in this Report to speak of them in detail. 956 Annual Report of New York A mass of facts and general information in regard to the cattle trade of the West were elicited during the discussions, which were of great value to the New York Commission, and those from States on the Eastern seaboard. The results of the series of investigations conducted by the Metropolitan Board of Health, were presented to the Conventiou by Dr. Morris, and attracted marked attention; especially certain plates and drawings illustrating the appearance of diseased matter under the microscope, and the various developments of cryptogamic growth in the blood and other fluids of diseased animals. RESOLUTIONS. Resolutions were adopted by the Convention, recommending to the Legislatures of the several States interested, the enactment of uniform laws, regulating the times for introducing Texas cattle into their respective States; the driving, shipping, feeding and trans- portation of cattle designed for market; instituting a system of inspection along the routes of cattle transit, and providing suitable penalties for persons difi'iising dangerous diseases from animals in their possession. MEMORIAL TO CONGRESS. The. convention also appointed a committee to present a memo- rial to Congress, asking for a small appropriation, to be expended under the direction of the War Department, in following up the disease to the pastures of Texas, and with the data obtained already, identify the fungus parasite which is always found associated with the disease, and is the probable cause of it. It is believed by your Commissioners, that with the knowledge already possessed by the scientific corps of the anny, of the Flora and Fauna of the regions traversed by the Texas herds, and with the facilities they possess for carrying out these investigations, the object can be far more speedily, thoroughly, and economically effected, than by the appointment of a civil commission, which must, after all, be largely dependent upon the War Department for assistance and protection. VISIT QUINCY AND ST. LOUIS. It was, in part, to gain an opportunity of conferring with the the Lieutenant General, and other officers of the army, on this sub- ject, that the Commission, on leaving Springfield, accepted an invitation from the Missouri delegation to visit St. Louis. Since State Agricultural Society. 957 meeting the army officers at St. Louis, no doubt is left in the minds of the Commissioners as to the success of an investigation conducted mider the direction of the War Department. Another, and the main object of the Commission in extending their trip to the Mississippi, was, to gain from personal observation and reliable data, correct information in regard to the magnitude of the Western cattle trade, and the modus o-perandi of feeding, handling and shipping cattle, as well as their treatment en route for Eastern markets. At Quincy, much interesting information was obtained. At St. Louis, through the kindness of gentlemen connected with the Board of Trade and the Board of Health, as well as of other business gentlemen of the city, the Commission had access to all the feeding grounds, stock yards, slaughtering establishments, packing houses and sale yards of the city and suburbs, and were furnished with a mass of statistics, of an exceedingly valuable character, as illustrating this trade. EXTENT AND DEVELOPMENT OF THE CATTLE TRADE. Formerly, say fifty years ago, the States east of the Alleghany mountains reared the meats consumed by their own population; They also reared and fatted much for exportation. As our foreign and internal commerce increased, and manufactures of various kinds sprung into existence, the soil was needed for the necessary pro- duction of grains, roots, fruits and other human edibles. The new States of the West increased in their herds of cattle, sheep and swine. They were driven on foot over the mountains, and found ready markets in those States which could no longer be supplied from their own soils. For many years past meat-growing in the seaboard States, has become unprofitable, and our almost sole dependence for that indis- pensable article is now from the broad grass and corn-growing regions south and west of our great lakes, and extending even beyond the Mississippi. The amount of our consumption is astonishingly large. New York city and its immediate vicinity now consume, directly and indi- rectly, about 7,000 beef cattle weekly, making an aggregate of more than 350,000 per year, valued at present prices at about $35,000,000. In addition to these, about 65,000 calves arrive in the city, which may be valued at eight dollars each, amounting to $520,000; about 700,000 swine, worth $10,000,000, and 1,200,000 sheep, worth $5,000,000, amounting in the aggregate, striking ofl' 958 Annual Report of New York fractions, to the round sum of fifty millions of dollars. All this is aside from the vast quantities of salted meats of beef and pork, which are also brought in and consumed in their cured conditions. A great majority of these live stock enter the State of New York by the railroads from Western States leading to Suspension Bridge at the Niagara river, and Buffalo, and by the Atlantic and Great West- ern road through Jamestown, in the county of Chautauqua, which connects with the Erie railway at Salamanca, in the county of Catta- raugus. The Erie railway also receives many at Dunkirk, in the county of Chautauqua, from the Lake Shore road, and also at Buffalo, whence they are directly transported to New York. The cattle arriv- ing at Suspension Bridge and at Buffalo, are transported over the Central railroad direct to Albany. Then a portion of them are distributed over various railways into New England, but the bulk of them are shipped over the Hudson river and Harlem roads direct to Ncav York, their final destination. A very considerable number of cattle are also shipped from the Western States by the way of Pittsburg, through Pennsylvania and New Jersey, and arrive at Jersey City and the Communipaw cattle yards, opposite New York, and make a portion of the consumption of the city and its environs. The journeys which these cattle make, according to the locality from which they are removed, occupy a distance of eight hundred to fifteen hundred miles by direct railway communication, taking from six to fifteen days in the time of transit, with the stoppages for feeding, water, and rest included. The cattle trains move at the rate of about two hundred to three hundred miles in twenty-four hours; but frequently from detentions, delays, and unavoidable accidents, they are delayed between their proper feeding places to thirty, or even forty hours. At an average, the feeding stations, where they can be taken out and fed, rested and watered, may be about two hundred and fifty to three hundred miles apart, but governed some what by the intersections and connections of different nt roads, as they diverge from or come into a main line running eastward, which embrace the traffic. WHERE OUR BEEF CATTLE COME FROM. The sources of supply previous to the last three or four years have been principally from the States west of the Alleghany moun- tains and north of the Ohio river, with the exception of a consider- able number from Kentucky and Missouri. They are composed of native stock mainly, with more or less admixtures of foreign blood, State Agricultural Society. 959 chiefly of the short horn breed many years ago introduced into our country from England, and to some extent, other improved English varieties, all which have improved the quality and value of our native herds. These cattle have usually been healthy, both in their native localities, and on their way to and arrival at our markets. Their usual condition, on their native feeding grounds, and in their various homes, on their removals for grazing and fattening (for they are a commodity of frequent sale and purchase among the breeders, graziers and feeders, who fit them in various stages for market), is generally healthy. Their pastures are good, and their feed usually abundant. Of consequence, when kept from adverse influences by local disease, which is quite unfrequent, they are in good condition when starting for market. No diseases prejudical to their flesh, or adverse to afibrding good meats to the consumer, have aflfected them, as a rule, when properly and honestly handled, •and our people have eaten freely of their flesh without fear of evil consequences. THE TEXAN CATTLE. But another and a widely different source of supply, within the last eight or ten years, has opened. For a very few years previous to the late civil war, some droves of cattle were brought into South- western Missouri, which found their way through the Indian territory west of the State of Arkansas. They were compara- tively few in number, and attracted little attention, other than that they were known to bring with them a peculiar local disease, which, under certain circumstances of exposure, hardship and abusive driving, they imparted to the native cattle of that then far distant region of Missouri. The rebellion at the South put an end, temporarily to that recently opened traffic, and from that prolific source of supply the Southern armies were mainly fed while thej^ held possession of portions of the lower Mississippi; and when the Northern armies gained possession, the outlet for them being cut oflT, and no hostile invasion occurring in that distant State, their herds increased in great numbers. WHAT ARE TEXAN CATTLE? They are the descendants of the Spanish herds introduced into Mexico in the sixteenth century, soon after the conquest of that country by the Spaniards. In that country of wide savannas and abounding herbage, Avith continuous green foliage throughout the year,- they increased, multiplied and spread over the wide territory 960 Annual Report of New York with a fecundity unparalleled in all previous histories of their race. Every Mexican State and appendage where settlements prevailed, whether occupied by Spaniard or Indian, were ranged over and grazed by these numerous herds. They composed the chief wealth of the sparsely settled population, and were mainly valued for their hides and tallow, which became large articles of export. Their flesh was a secondary object, and of little value. Texas, when admitted into the United States, was full of them, and they soon became the chief sources of beef supply to New Orleans and the other cities and towns on the Gulf and Lower Mississippi. CHARACTER AND PROPERTIES OF TEXAN CATTLE. In stature, they are medium, coarse and sleazily biiilt, with large bone and horn; they are but moderately fleshed, and that flesh, in its natural wild condition, when compared with our own good native beef, is coarse, flabby and stringy. Savage and semi-wild in habit, they come into domestication reluctantly; yet, in many instan- ces, when well tended and fed on our best pastures, and " finished off" on corn, after the manner of our good graziers and feeders, they yield a passable carcass of beef, but at more expense of food than those reared and fed in our own States. They mature tardily, at a not less age than five, six, or seven years, and at such ages, their live weight, in good condition, ranges from nine to twelve hundred pounds when brought to market. THEIR MODE OF REARING AND TREATMENT. They are owned in Texas, in large herds, ranging from a hundred to several thousand, in the hands of a single individual. No fenced pastures enclose them, and they range over the country in multi- tudinous droves, for many miles away from their owners' localities, all sexes and ages running together. One man may own a thousand head or more, and his only personal property aside from them, may be a few semi-wild horses, a little household tackle, his shooting and cutting irons, and a raw-hide tent, or log cabin, where he lives and rears his family. - Running wild, the cows drop their calves at all seasons of the year, and rear them as best they may, in their own wild and vagrant manner. At a certain season annually, the several owners turn out, hunt, and collect their cattle from their various ranging grounds and drive them into enclosures made for the purpose — each one of a year old and upward having the brand or mark of their owner State Agricultural Society. 9gX upon them. Here the calves are seleeted and branded with their several owners' marks, or initials, the males castrated, those selected for driving away and selling taken out and retained, and the rest ^ turned out again for grazing. Such is their rearing and treatment. DRIVING, TRANSPORTATION, AND SELLING. When collecting for sale and a market, those selected and fit for the purpose, mostly steers and cows, are separated from the maju herds (each owner knowing his own brand — and it is but 'justice to say that they are scrupulous in acknowledging among each other that mark of ownership), and strictly guarded by the drovers from getting back into the main herds. When ready for a start, they are then hurried out from their accustomed ranges into new grounds on their way to market. In many cases they are mhumanly driven, without sufficient food or water. WHEN INTENDED TO GO ON SHIPBOARD. On arriving at the landing places of the steamboats on the Gulf, or Mississippi and its tributary waters, they are rushed on to boats in the most brutal manner. When refusing, by fright or terror, to go on board quietly, they are lassoed by the horns, necks, or legs, as chance or opportunity may offer, and hauled on the decks, w^here they are crowded into the closest possible space, and securely railed in from escape. There the poor suffering beasts remain, tortured by hunger and thirst for several days together, with nothing to eat and no opportunily to drink, from their huddled condition, although a sea of water may be all around them, until they are taken to their destination on the rivers several hundred miles above, or below, and landed. Those destined for immediate slaughter in the lower cities, on landing go immediately to the slaughter houses, or may be fed for a few days in yards until marketed. Those intended for grazing in Eastern Missouri, Kentucky, Iowa, or Illinois, go to the readiest landings on the Mississippi, or Ohio, and are there taken off and driven, or put in railway cars for transportation to the inte- rior. We have been told on credible authority, that as many as eleven hundred head had been crowded and transported on a single steamboat to St. Louis, and perhaps nearly equal numbers on a single boat to Cairo, at the mouth of the Ohio. In this wretched condition at landing, many of them are found dead; others are terribly bruised and mutilated from crowding, and getting down and trampled upon [Ag.] 61 962 Annual Report of New York by th'e others while on the boat — so much so as to be thrown over- board, or put aside from driving, or car transportation at all. Those able to be put on the cars are then, without food, in many instances, transported two hundred and twenty-eight miles — sometimes occu- pying two or three days on the journey, without food or water — to Tolono, the principal distributing point, where they are disembarked from the cars, and driven to their feeding or pasturing grounds. To say that these poor, abused, emaciated cattle, having lived for a week, or ten or twelve days, without food or water, or with so trifling an amount of either, as only to tantalize their existence into the desperation of misery and torture, with their systems relaxed almost to a state of collapse, can be healthy, is to assert^ fact utterly inconsistent with the laws of either health or animal physiology. The normal causes of disease — -elsewhere discussed— r existiug within them, become active, and, when ranging with thp native cattle with which they come in contact, they impart the dis- ease to them, or leave it by the spores of their excrements on the cars and on the roads, in the streams, or the pastures and grasses over which they pass, to be imbibed or drawn in by the animals which follow them. Such is the condition and treatment of a large proportion of the Texan cattle which come into the upper States by boat transportation on the Mississippi. INLAND MOVEMENTS OP THE TEXAN CATTLE. Gathered into their several herds for driving northwa^^'d, froia the central portions of Texas, they are rapidly hurried forward, sometimes, as we are informed, at the rate of more than forty miles a day on their first starting — they are driven thi'ough Upper Texag and across the Indian territory west of the State of Arkansas, graz- ing on the open prairies and wooded ranges by the way, into Kansas, to a station called Abilene, in the central part of Kansas, one hundred and sixty-three miles west of Leavenworth. The journey to Abilene may be from five hundred to eight hundred miles, according to the parts of Texas from which they first started. Abilene is now the great point of arrival for the cattle from the interior of Texas. Here have recently been built large yard accommodations for their collection, sale and purchase as they arrive; and immense numbers, sometimes as high as twenty-five to fifty thousand in number, are pastured and herded in the vicinity, awaiting a market. Here they are bought by the large cattle dealers of the States east, and driven or "carred" forward to their State Agricultubal Society, 963 various points of destination for feeding. They usually arrive at Abilene in a moderate condition of flesh — some better, or worse than others, as they have been driven, fed and watered by the way. They remain in the vicinity oi Abilene sometimes for Weeks and months, as purchasers may arrive from the East, or as the condi- tion of the cattle may need recruiting for sale. As the land is mostly prairie, with abundant grasses growing, and mainly unset- tled, pasturage costs little or nothing. They only require herding, which is cheaply done by their owners. t These cattle are bought in Texas for six to eight dollars a head, and their entire cost on arriving at Abilene does not exceed ten to twelve dollars each, thus establishing the foundation tor "CHEAP BEEF." Here lies the solution of the grand question, why such compara- tively inferior animals as the Texan cattle have been introduced into the wide cattle breeding and gracing regions of our Northwest- ern States. That they are " cheap," in every signification of the word, is certain. They bring the same seeds of disease with them to Abilene, as do the more southern herds which come up the river to Cairo and St. Louis^ and under like circumstances impart it as readily to our native stock as they.* But allowing that quite a percentage of them die by abuse, and their own native disease, still, the wide margin of the whole cost left on the survivors, below the values of the native cattle of the Northwestern States, gives the ** handlers " of them a large profit. The losses sufiered by the owners of native stock, which the Texan cattle have imparted to them, have been very heavy, and could they be thrown upon the owners of the Texans, the question of " cheapness " in their original cost, and the expense of " hand- ling " them, might prove altogether a difierent matter. What the proportionate number of Texan cattle, which reach our markets, may be to the natives, is difficult to say; and how much their considerable numbers may reduce the prices of beef at our seaboard cities, if they were not available, is simply a matter of conjecture. There are two distinct parties to the policy of using Texan cattle. It can be proved, by credible witnesses, among the graziers and drov- • It is, perhaps, proper to say that, from aU the recent evidence gathered by the Com- mission, there can be no doubt that a much larger proportion of those Texas animals that come north by the Cairo and Mississippi route, are badly diseased, than of those which are brought by the Kansas and Abilene route. 964 Annual Report of New York ers, in a court of justice, that the Texans are a profitable, useful and valuable class of beef-makino^ material to our Western o-raziers and farmers; and it can be equally well proved by other witnesses, in the same occupation, that they are a scourge and a curse to the country, and that it is a calamity that they were ever introduced, and will remain a calamity so long as they are suffered to enter our States. These are questions which we need not argue. They who pur- chase, feed and handle them, say their flesh is good, palatable and healthy to the consumer. When it is conceded by good physiolo- gists that a coarse, raw-boned and streaked fleshed, six or seven years old beast of any kind, is equal in tenderness, juiceness, flavor and nutritive quality to a well constituted, small-boned, nicely fattened one of three or four years, and the general sentiment of the beef- consuming population concur in it, the question will be settled in favor of the Texans, and we fancy not until then. The fact of disease existing among the Texans, left out, would do much in their favor. But that fact admitted, sound policy, and a due regard to the sanitary condition of our population, may well interfere with he decision; and the sanitary question is probably the only one with which our State Legislature has a right to interfere. KEGULATIONS ATTENDING THE TRANSPORTATION OP CATTLE IN THE STATE OF NEW YORK. This is a question, out of our own State, either way, with which ■we have nothing to do, and can only allude to it as touching our government in the matter. As a sanitary measure, we take it that the Lesrislature has entire control over it. A statement of the facts regarding the cattle transportation through the State will explain. In the first place, the great lines of railway running from the western line of the State to Albany and New Yorh, appear to have done and are doing all in their power to accommodate the cattle traffic, both for the public and the owners of stock to the best advantage. The New York Central railroad, at its cattle station at Suspension Bridge, where it receives stock via the Great Western, through Western Canada, or Ontario, from the Michigan Central road, has capacious and excellent yards, with good supplies of forage and water, where cattle and other stock are yarded, fed, watered, rested and shipped into their own cars for Albany. At Buffalo, this road has also extensive yards of the most com- modious character, fenced, paved and sheltered, with abundant pro- visions of forage and water, where the stock is received from the State Agricultural Society. 955 Lake Shore and Canadian Grand Trunk roads, and treated as at Suspension Bridge, and again shipped into their own ears for Albany. We hear of no abuses in the cattle transportation on either branch of this road. The Erie railway now receives the chief part of its stock for transportation, which comes in over the Lake Shore road, at the yards of the Central road in BuJSalo, although we understand it contemplates erecting commodious yards of its own contiguous to the Central yards, on land which it now owns. It also receives a portion of its stock at Dunkirk, the western terminus of the road, and also at Salmanaca, four hundred and fifteen miles west of New York, from the Atlantic and Great Western road. Here, we under- stand, it takes the stock cars from the latter road, as they arrive, and runs them to Campville, half way the whole distance between Jersey City and Dunkirk, two hundred and thirty miles. At Camp- ville, all their stock are intended to be transhipped, fed and watered for the remainder of the journey, although some of it is hurried through without either. The Atlantic and Great Western road enters the State of New York at its western line, about fifty miles west of Salamanca. How far its stock-feeding place is west of here, we are not informed, but at Jamestown, thirty-four miles west of Salamanca, we learn that portions of its stock are put oflf the cars, yarded, fed and watered. They are again taken aboard, and proceed to New York by the Erie road, from Salamanca. The Lake Shore road brings the great bulk of the stock from the West, and delivers it to the Erie and Central roads at Dunkirk and Buffalo, as before stated. Thus it will be seen, that when stock arrives from States west of New York, our own roads are prepared to receive and treat it in a proper manner, and were there no further difficulties connected with the traffic, our people, or Legislature, would have little to do in the matter of regulating the transporta- tion. But stock of all kinds intended for slaughter arrive at our Western cattle yards in all possible conditions and circumstances. THE DROVERS, CATTLE OWNERS, AND DEALERS. These are a numerous, and in the aggregate, an active, influential class of men, embodying great business experience, frequently of large wealth, making extensive transactions, handling great amounts of money, and usually fair in their dealings. Their homes are on all the lines of railway, and frequently off from them, extending 966 Annual Report of New York from Maine, and Boston, and New York city, to Kansas. They are alert in movement, quick in bargains, bold in their operations. Their business is usually profitable, but sometimes the reverse. They consider their word as good as their bond, which it should be, as heavy amounts of property frequently change hands among them, with nothing but a slight written memorandum, or a witness called at the moment to attest their bargains. Detected in an unfair or under-hand transaction, they quickly lose cast, and are ruled out of the circle of fair dealing. Many among them, in the chief Wstern cattle States, are large breeders, graziers and feeders of stock, and they embrace bankers, merchants, lawyers, and men of almost every profession connected with the ownership of laud and capital. Their individual transactions amount, in the aggregate, from a few thousand to more than a million or more of dollars annually. One cattle dealer, Mr. Alexander, alone, for the year ending May 1st, 1868, sent to New York market about 40,000 cattle. About 9,000 of them were fatted on his own farms, which consist of some 45,000 acres in one body in the county of Champaign, Illinois, and 31,000 head were purchased of other farmers and dealers. The value of these cattle in New York, including cost at home, and transportation, was about $115 each, making in the aggregate, $4,600,500; and his business for the current year will exceed that of the last about twenty per cent. These cattle all, or nearly all, passed over the Pennsylvania and New Jersey rail- ways to Jersey City. Chicago, Toledo, Buffalo and Albany are the chief wmj cattle markets on the great routes to New York and the New England States, where dealers and drovers congregate in large numbers for sale and purchase; so that, in frequent cases, cattle change owners two or three times after their first shipment before reaching their final destination. In justice to a great majority of the drovers, we take pleasure in remarking that they are careful of their stock in transportation, liberate them from the cars at proper points, and care, for their health and welfare by food, water and rest, so that they arrive at market in good condition. Yet, it must also be remarked, there is another class of drovers and dealers, trading chiefly in the inferior and cheaper classes of cattle, who pay little regard to the impulses of humanity, and rw?* their cattle through to market from their distant Western shipping points on the cars, in the most cruel and merciless way, for three, State Agricvltural Society. 9ig7 five, or even more days and nights together, as the case may be, with little, if any, food, water or rest on the route. In such cases the poor suffering animals become jaded with fatigue, almost fam- ished with hunger and thirst, and lose much flesh. In frequent instances they become diseased, or falling down in the cars and tramped on by the others, arrive in a most pitiable condition of bruises, sometimes broken limbs, and utterly disordered con- dition. Cattle apparently well at the time of their shipment, or having incipient ailment only, frequently have disease break out among them which is only discovered at the transhipping or car- changing points, when they are unable to go further. At these points, usually Chicago, Buffalo or Albany, a class of "shyster" butchers congregate on the chief cattle-arriving days, who buy these maimed, bruised and diseased animals, drive them slyly away, slaughter, and cut them up, taking out the bruised or diseased parts, and sell them in the meat markets and stalls to the unwary and unsuspecting, who are ignorant of what they buy, only looking at cheapness in the price. Such meat must be diseased, and unwholesome. Nothing short of stringent laws for the inspection and condemna- tion of such cattle will correct this dishonest traffic, and save the" community from the bad effects of consuming such unhealthy food. Sanitary protection of the community in our cities demands it. The: numerous instances of such traffic which have come to the eyes and; ears of the Commissioners, compel them to expose these glaring; impositions, which from small beginnings have now become so fre- quent as to demand the action of the Legislature to enact strong and positive laws for the protection of -the people from further impositions of the kind. To follow this chea'p and unwholesome trade, the Texan and the inferior classes of our own native stock offer the greatest induce- ments for unscrupulous men. The poorer classes in our cities clamor for cAeap meats, and as these kinds of stock are offered to them comparatively \oyj in price — but in reality the dearest, when the amount of bone, gristle, and offal is considered, and which they do not consider — the imposition upon them is cruel and inhuman. Yet the Texan cattle are not altogether of the classabovenamed. Many of them, when well wintered in the Western States, with good summer pasture, and corn feeding following, produce good and healthy and palatable beef, even with the signs of their native previous disease lying latent within them. But, with the over- driven, jaded and abused ones, the disease is liable at any time to 968 Annual Repobt of New York break out, and communicate to other healthy ones with which they come in contact and association; or, they may leave it in the cars in which they are transported, in the streams or pools from which they drink, the pastures on which they graze, or on the roads over •which they are driven. SHEEP AND SWINE. The abuses which have been recounted in regard to cattle, also appertain to sheep and swine, but not to an equal extent. They equally require inspection, and condemnation if necessary, at the cattle yards and shipping points, as well as rest, food, and water. Large numbers of diseased, maimed and bruised ones are bought, slaughtered and sold in the markets, and consumed by the unsus- ecting buyers of cheap meats, quite as deleterious to their health as the bad beef, and in this disposition, the buyers and consumers require equal protection from their bad effects. REGULATION OF STOCK TRANSPORTATION. From the attentive observation which the Commissioners have been able to make, and the various information they have obtained, they are satisfied that laws regulating the transportation of live stock to market, should embrace — 1. A careful and thorough inspection of all stock on their arrival at the transhipping yards in the State. 2. The selection and condemnation of all diseased, maimed and dangerously bruised animals, which, if unable to be immediately removed into quarantine, or driven into the country, out of the way of healthy animals, should be immediately taken to rendering houses, and their carcases summarily disposed of. 3. A rest to the stock of full twenty-four hours, in which they have sufficient wholesome food and water. 4. That they should not remain on the cars a longer time than twenty-eight hours (barring unavoidable delays and accidents to the progress of the cars), and that their passage between Suspen- sion Bridge or Buffalo and Albany, should not exceed that length of time. At the latter place they should be again unloaded for food, and rest twenty-four hours before shipped to New York. 5. Stock passing by the Erie road, or coming in by the Atlantic and Great Western road, should be unloaded at Campville, and there fed, watered and rested as at Buffalo, before proceeding to Jersey City or New York. And in the latter lalace they should, on their State Agricultural Society. 959 arrival at the yards, be fed and watered, unless they proceed imme- diately to the slaughter yards; and also that power be given to the State Commissioners to make any other, or additional regulations, which the necessity of the case may demand. OBJECTIONS TO THESE LAWS. It may be complained on the part of some of the drovers and dealers that such rules may be too stringent; that it will bear hard on those who have invested heavy sums in the purchase of their stock; that they are unnecessarily kept out of a return of their money; that a rising or a falling market may seriously affect such delay, and prove greatly disadvantageous to their interests. In some instances it may be so; but is not the health and welfare of the people who consume their stock to be equally considered ? Animals pushed with such headlong speed through from their first shipment to market, lose much flesh and weight — an average of quite one hundred or more pounds per head — and the tissues of their entire system are turned into a feeble, disordered and feverish condition, to say nothing of such barbarous and inhuman treatment to the poor brutes themselves. And this treatment is oftentimes greatly aggravated by the merciless beating, punching with iron- sharpened goads, and maltreatment they receive in their " hand- ling " by some of the drovers and their attendants. Again, there are great numbers of first class cattle, sheep and swine, well fattened, of large size and heavy weights, which must, of necessity, be shipped and transported with care. They are valuable. Their owners know it, and are watchful that they be rested, fed and watered at proper times and places. It is for their interest so to do, that their stock may arrive at market in good condition, and bring good prices. They make no complaint of delay, or of losing time and capital in their transportation. "A merciful man is merciful to his beast," and if the owners of inferior stock show less regard to their meaner or cheaper things, they should be compelled, by all considerations of humanity, as well as sanitary law, to comply with like conditions which the owners of better cattle impose upon themselves. REGULATIONS OF OTHER STATES. Although it is to be hoped that the several States west and south of us will do their whole duty in this matter, by enacting such laws regulating the stock trade and transportation, as may be needful \ 970 Annual Report of New Yore! within their own boundaries, the State of New York should, irres- pective of their action, do its whole duty to itself and its people. Our population is rapidly increasing. We must receive the bulk of our meats from the West. It is indispensable to the health of that population that these meats should be wholesome and of good quality. It is an imperative duty, so far as the law-making power is concerned, to render them as much so as possible, and the Com- missioners would fail in a grave and solemn duty did they not present all the facts and considerations within their power to the consideration of the Legislature. OBSTACLES IN THE WAY OF INVESTIGATING THE NATURE OF THE DISEASE. As this peculiar disease had never been known in the Eastern States, and had nowhere been investigated, the Commissioners were greatly embarrassed when its appearance in New York created so much alarm in the month of August last. They were in no con- dition to institute a series of investigations under their own direc- tion, for their duties called them into every part of the State, and required them to be on the move a large portion of their time. The small appropriation made for the use of the Commission, under the act of 20th April, 1866, having lapsed (under the two years Constitutional provision), the Commissioners were without funds to pay their personal expenses, much less to call into service such professional gentlemen as were competent to carry forward the work of investigating the disease. TAKEN UP BY THE METROPOLITAN BOARD OF HEALTH. By an unlooked for and most fortunate concurrence of circum- stances, the Commissioners were relieved from their embarrassment by the action of the Metropolitan Board of Health, which had, at the first outbreak of the disease at Communipaw on the 8th of August, organized a special committee of its medical officers to investigate the nature of this fearful malady. It will be recollected that at the first meeting of the Commis- sioners in Albany, on the 18th of August, Dr. Moreau Morris, Sanitary Inspector of the Metropolitan Board of Health (who had been- specially charged by that body with the inspection of all cattle arriving in the Metropolitan district), was appointed Assistant Com- missioner and clothed with State authority to act along the lines of approach to the city, while the Commissioners themselves were engaged in the other parts of the State. Statu Agricultubal Society. g^j LETTER OF DR. HARRIS, REGISTRAR OF VITAL STATISTICS. Before the Commissioners had left Albany, on the 19th of August, Dr. Harris, Eegistrar of Vital Statistics, under whose direction the investigations of the Metropolitan Board were being conducted, communicated to the Commissioners the desire of the Metropolitan Board of Health, that the State Commission should assume the conduct of these investigations; but no action could be taken in regard to such proposition, until the Commissioners could be spared from the duties then pressing upon them in the Western parts of the State. OPERATIONS OF THE SPECIAL COMMITTEE OF THE METROPO- LITAN BOARD OF HEALTH. When the Commissioners finally reached the city of New York on the 2d of September, they found the measures that had been adopted by Dr. Morris under the double authority of the city and State, were so very judicious and salutary in all their results as not only to give entire satisfaction to all concerned, but to render it obvious that this cooperation of the Board of Health and the Com- mission must continue as begun, and that there must be an entire unity of plans and purposes. Already the unwearied labors of those gentlemen connected with the Board who were studying the disease, had been crowned with discoveries of an extraordinary character and the acquisition of a large amount of valuable information, not only in relation to the Texas disease, but to Pleuro-pneumonia, also. PROPOSITION TO TURN OVER THE INVESTIGATIONS TO THE STATE DECLINED. It was at this time that the medical officers of the Board of Health who were engaged in these investigations, again, and more formally, expressed their wish to wholly relinquish their scientific investigations, and transfer whatever facilities they possessed for carrying them on, to the State officers acting under the special law for preventing the spread of infectious diseases among cattle. But this proposition the State Commissioners unhesitatingly declined, and earnestly requested that the gentlemen who had com- menced these labors in the Metropolitan district, should continue them. It was eminently proper that the thoroughly scientific and devoted medical officers, whose comprehensive and exact researches into the causation and prevention of pestilential and infectious dis- eases had already commanded the respect of the medical profession, 972 Annual Report of New York and had shown how to apply such knowledge in disarming the most threatening of human pestilences in former years, should con- duct and complete, in their own way, their inquiries concerning this cattle disease. SPECIAL REPORT. Yielding to the request of this Commission, the investigations of these medical officers of the Board of Health were continued during the remainder of the season, and this Commission herewith submits a body of evidence which the Metropolitan Board of Health has caused to be prepared in the interests of the public health and sanitary knowledge. Although this evidence constitutes a portion of the report of the Metropolitan Board of Health to the Legislature upon the public health of the Metropolitan district, yet, inasmuch as it also consti- tutes the most important part of the record concerning the Texas cattle disease as it was developed in the State of New York, this Commis- sion, with the full approval of all concerned, has obtained the use of that " Special Eeport" to be presented in connection with its own. It is not necessary for this Commission to add a single word of praise in regard to this " Special Report," as it cannot fail to be appreciated by the State, and by all persons interested in the appli- cations of scientific and sanitary knowledge. INSUFFICIENCY OF THE ACT OF TWENTIETH APRIL, 1866 As the act of April, 20, 1866, under which the Commission has acted, was framed to meet a foreign enemy and prevent it from getting a foothold in this State, the Commissioners have found it very difficult to perform the duties demanded of them, in protecting the State from an infectious disease prevailing in the neighboring States from which we are receiving daily supplies of meat for our markets. To meet such a condition of affairs as has existed in the cattle trade during the last half of the year 1868, and in accordance with the resolutions adopted by the Springfield Convention of Cattle Commissioners, the draft of a law, regulating the trade, transporta- tion and handling of cattle in this State will be submitted to the Legislature for its consideration. NO FUNDS TO MEET EXPENSES. The appropriation of April 20, 1866, having lapsed, as before stated, the Commission was much impeded in its work, just at the time when funds were most needed and the most vigorous mea- State Agricultural Societt. 973 sures must instantly be taken to check the progress of the disease. After a few weeks, however, an arrangement was efiected with the Mechanics' and Farmers' Bank of Albany, under the advice and with the concurrence of His Excellency Governor Fenton and the Comptroller, by which some of the most pressing demands were met. CHANGES IN THE LAWS ARE SUGGESTED. By the eleventh section of the act, which now governs the Com- mission, the expenses of the Assistant Commissioners at the various cattle yards and stock depots throughout the State along the routes of cattle transportation, are to be paid by the counties in which these yards and depots are located, respectively. To throw such burdens upon the citizens of such counties is manifestly unjust, as they are in no sense responsible for the evils that are introduced by stock en route through the State for an Eastern market; nor are the county boards of supervisors proper judges of expenditures ordered by State Commissioners in such an emergency as occurred in August last. It is earnestly recommended by your Commissioners, that all expenses incurred under the act of April 20, 1866, not already met by the railroad companies and owners of live stock, be assumed by the State, and that the counties of Erie, Chautauqua, Tioga, Albany, Dutchess, Columbia, Orange and New York, be reimbursed for money already paid out, if any, on such account. ESTIMATED EXPENSE TO THE STATE OF THE TEXAS CATTLE DIS- EASE IN 1868. The expenses incurred under the orders of the Commission cannot, at this moment, be stated with certainty, as the accounts have not all been presented, but will not materially vary from the following Statement. Expenses in the Albany district, including Rensselaer. . . $4,098 42 do Tioga do 162 99 do Erie do 930 00 do Chautauqua do 276 00 do Orange do 194 83 do Columbia do ^ do Dutchess do >- 3,900 00 do New York do ) Total *P,562 24 • Of this sum there has been paid by the county of Erie already, $345.98; Chautauq[ua, $150 ; Orange, $150. 974 Annual Report of New York The Commissioners have drawn from the Mechanics' and Farnl- ers' Bank of Albany, and paid out, for all purposes ($2,230) two thousand two hundred and thirty dollars, of Avhich sum ($400) four hundred dollars was used to defray expenses in the Metropolitan district; mailing a total cost to the State, when all known demands are paid, of about $11,792.24, for which an appropriation is asked. Although it is to be hoped that no considerable expenditure will be necessary during the year upon which we have entered, prudence requires that a sufficient fund to meet emergencies be placed at the disposal of the Commission. CONCLUSION. In conclusion, the Commission cannot but feel, that though the State has barely escaped a great calamity, the visitation of the Texas cattle disease has not been an unmixed evil. As direct resultants of investigations connected with this cattle disease, some of the most brilliant and useful discoveries in sani- tary science have been achieved. Pleuro-pneumonia has been successfully treated, and a remedial agent of incalculable value has been brought into common use among the herds and flocks of the State. With reasonable care on the part of stock o\NTiers in keeping themselves supplied with carbolic acid in some one or more of its forms and using it freely on their premises, there appears to be a perfect immunity from diseases that have, hitherto, carried inevi- table destruction wherever they appeared. Further than this, the observations of the Commission warrant the belief that this same agent possesses curative properties of the greatest value when applied to "foot rot" in sheep. From the fact that carbolic acid acts specifically upon all germs, or seeds of disease that are propagated in a manner similar to the spores, or fungus parasites of the Texas disease, it is not too much to hope that it may be used successfully in the treatment of many diseases in animals heretofore regarded as incurable, especially the Glanders in horses; inasmuch as the recent researches of the world- renowned Hallier, of Jena, have brought to light in the nasal discharges and circulating blood of glandered horses, the conio- theciwn equinum* a microscopic parasite of the same genus as the coniothecium stilesianum, which is the active agent in the Texas • See last plate of illustrations in the special report of the Board of Health. State Agricultubal Society. 975 cattle disease, and is effectually destroyed by verv weak solutions of carbolic acid. Indeed, in many aspects of the case, the experience of the past year in connection with the Texas cattle disease, has been full of interest to the citizens of this State, whether engaged in the handling of live stock, or deriving their supplies of meat from the public markets of the large cities. All which is respectfully submitted. M. R. PATRICK, LEWIS F. ALLEN, JNO. STANTON GOULD, Albany, January, 1869. Commissioners. 976 Annual Report of New Yobk DOCUMENTS REFERRED TO IN REPORT OF COMMISSIONERS. (A.) THE CATTLE DISEASE IMPORTANT PAPER FROM THE COMMISSIONERS. Upon the request of the Governor, the undersigned Commissioners convened at Albany on the 17th instant, and after careful deliberation, make the following announcement to the public : In view of the fact that the Commissioners appointed in pursuance of chapter 740 of the Laws of 1866, have power and are directed to establish all such quar- antine or other regulations as they may deem necessary to prevent the spread of the disease (rinderpest or other contagious disease) in its transit in railroad cars, by vessels, or by driving along the public highways ; and also to appoint Assistant Commissioners, whose duty it shall be to carry out " such quarantine and other regulations ;" and who, in order to eflfect this, are clothed with all the power con- ferred by this act on the said Commissioners, or their agents or appointees, in order to obtain a perfect history of this disease for future use ; and also to subserve most fully the purpose of this Commission, they have deemed it advisable to select the most practically scientific men in the State to act as such local Assistant Com- missioners, or health officers, to carry out the intentions of the law and to preserve proper medical records. They have also appointed Assistant Commissioners for the various localities infected or suspected of having been infected or exposed to the infection known as cattle disease, to the end that all persons dealing or having an interest in cattle in the various States, shall be made acquainted with the measures which this Board has deemed prudent to adopt, and in order that as little delay may be caused in the movement of such cattle, or loss to the owners thereof, as is consis- tent in the present emergency. It is believed that the sanitary and other author- ities of adjoining States, will act in harmony with this Commission in promptly carrying out measures which it is hoped will speedily arrest the disease. General instructions will be given to all such Assistant Commissioners, varying, perhaps slightly, depending upon the circumstances which may surround each locality, from time to time changing such regulations as they may deem necessary to prevent the spread of disease on its transit on railroad cars or by driving along the public highways : Firstly. All cars containing cattle will be stopped at the most convenient point on or after entering the State, and if such cars are not in a proper sanitary con- dition, the cattle, even though healthy, are to be disembarked and the cars thoroughly cleansed and disinfected. After the completion of this process, if the cattle continue healthy, they can be reshipped ; such cars upon reaching such further point or points of inspection as may be designated by this Board, will State Agricultural Society. 977 again be inspected, and if found unclean, will be subject to such other stoppage, examination, cleansing and disinfection as may be necessary. Secondly. If at any point on the line of said railroad or railroads, the said Assistant Commissioners shall learn hj inspection or information of the existence of disease in cars, they shall be stopped at some convenient point on the road, where they have reason to believe that no infection exists, such cars thoroughly cleansed and disinfected, the sick taken from the well, and properly isolated and kept under proper sanitary restrictions and medical treatment. If any such cattle are slaughtered, the skins must be thoroughly disinfected, properly preserved and kept on the premises, or deeply buried. The carcass of the animal itself should be either tried into tallow in the most approved manner, or else, with the offal, etc., should be deeply buried. Cattle sick with this disease should not be slaugh- tered until in the judgment of the Commissioner, or his Assistant on the spot, they are past recovery. The well cattle exposed to this disease should be removed from the cars to some distance, and furnished, as above directed, with a sufficiency of water and food, with salt at will, and kept under proper surveillance for such period as may be directed from time to time. All places or yards, or fields in which cattle are sick, or in which cattle have been exposed to disease, are to be kept disinfected. The sick cattle, and all such as have been exposed to disease, and in which the disease may be incubating, should be kept in an enclosure separated from all well cattle by a neutral ground of at least one thousand feet. All cattle yards or places in which diseased cattle, or cattle exposed to disease, may have been, must be thoroughly cleansed and disinfected before being agaia used for the herding of other cattle. If in the judgment of the Commissioners or their Assistants, such yards or reception places for cattle are not susceptible of being cleansed and disinfected, they will be cleansed, &c., as well as may be, closed, and other cleaner places being substituted therefor. Thirdly. All cattle being sent to market, on entering the State, or being car- ried on vessels in the State, or by driving on the public highways, will be sub- jected to the same careful inspection and sanitary restrictions as above directed fcr those carried in the cars. ^ The clothing of persons engaged in the care of diseased cattle, or in the slaugh- tering or rendering of the same, or in any employment bringing them in contact with them, or of those employed in the care of suspected cattle, should be cleansed and disinfected before leaving the premises. The Commissioners will prohibit the slaughtering of animals for beef after they have been exposed to the contagion, until all sanitary restriction is withdrawn therefrom. DISINFECTION-. For disinfection of the cars, yards and other places, the Assistant Commissioners will be instructed to depend mainly upon the use of carbolic acid, the various pre- parations of chlorine, quicklime and the different sulphates. Attention is also called to the directions for disinfection given by the Board of Health, New York, and published on Saturday, the 15th instant, in most of the papers throughout the country. The aforesaid Assistant Commissioners will be directed to cominu- nicate daily with the Governor, each of the Commissioners, and President of the Metropolitan Board of Health, giving information and receiving additional instruc- tions. As the carrying out of these regulations involves a knowledge of the principles of Quarantine, Dr. John Swinburne, Health Officer of the Port of New York, has [Ag.I 62 978 Annual Report of New York been entrusted with the general sanitary supervision, and will at once make a tour of the State to superintend the carrying out of the above regulations. Dr. Jacob S. Mosher and John Phillips, of Albany, and Dr. William Manlius Smith, of Manlius, have been appointed assistant Commissioners. Others will be appointed soon. M. R. PATRICK, Chairman. JOHN STANTON GOULD, > Commissioners LEWIS F. ALLEN, 5 ^«'"™^««*«"«'^«- Albany, August 18, 1868. (B.) THE CATTLE DISEASE. OFFICIAL EEPOET OP THK CATTLE DISEASE BY THE COMMISSION OF THE STATB TO INQUIRE INTO ITS ORIGIN AND CHARACTER. The undersigned. Commissioners appointed under the act of the Legislature of the State of New York, passed April 20, 1866, for the prevention of the spread of the Rinderpest, and other infectious diseases, having, since the publicntion of their regulations on the 18th August, had an opportunity of seeing many cattle sick of the Texas cattle plague, and of learning much respecting its history and the circumstances attending its manifestations, and knowing the anxiety of farmers in various parts of the State to obtain information respecting it, have deemed it proper to communicate the following facts for the information of such as are interested in cattle and beef: 1. Hoio the Disease is Communicated. — We have not heard of a single case of the disease having been taken by any animal that has not been in contact with Texas cattle, or with their excretions. We have had authentic evidence that Texas cattle that have passed over a road, dropping their excrement thereon, have coirf- municated the disease to native cattle +,hat passed over the same road forty-eight hours afterward. We have no evidence whatever that native cattle afflicted with the disease have in any case communicated it to other native cattle ; at the same time we have not felt at liberty to act upon the negative testimony, but in our quarantine regulations we have acted as if the disease could be thus communicated. Sick and healthy animals have been mingled together at several of our quarantine yards, and in no case have the healthy animals yet developed the disease. 2. The Disease is Aggravated by Motion, and Ameliorated by Fresh Air and Repose. — We have abundant evidence upon this point, which is entirely satisfactory to us. Wherever cattle have exhibited the earliest symptoms of the disease, and have been taken from the cars and allowed suitable food and drink, with rest and fresh air, they have invariably recovered speedily ; while those which have exhibited the same symptoms, and have gone forward in the cars from sixty to one hundred miles further, have rapidly developed the disease in its most malignant form, and it has been necessary to send them to the bone-boiling establishments. It is, therefore, decidedly for the interest of the drover to withdraw the cattle from the cars at the appearance of the earliest symptoms, and subject them to the hygienic measures above spoken of. State Agricultural Society. 979 3. The Earliest Symptoms of the Disease. — The first symptom of the disease in all the cases observed by us and by our Assistant Commissioners, is an appearance of languor and weariness, which is unmistakable; the head droops, the ears hang down, the eyes are staring. This sometimes occurs when cattle are terrified, but the stupid stare of the cattle affected by the disease is very different from the furious stare produced by terror. The back is arched, strong efforts are made to dung, which are often ineffectual, the droppings being unusually dry, scanty, and stained with blood. These symjJtoms are invariable. The m-ine is generally dark brown in color, and commonly called "black water." This symptom is not, however, always present in the earlier stages of the disease. The coat is generally rough, the hairs standing almost erect. The horns are hot, the nose dry, and a frothy drool from the mouth ; flies settle in great numbers upon them, and the animal rarely makes an effort to brush them off. These latter sj^mptoms are not invariable, especially the roughness of the coat. In cases of doubt, the most reliable distinguishing mark is undoubtedly afforded by the thermometer. If, in connection with the before named symptoms, the thermometer, iiitroduced into the rectum for two or three minutes, shows a temperature much higher than one hundred degrees Fahrenheit, the animal may be safely pronounced to be suffering under the disease. In some cases it has come up to one hundred and nine degrees Fahrenheit. 4. How the Meat of Diseased Jliiimals may he Distinguished. — The fat has a deep or high colored greenish yellow appearance, and has not the firm resistance of health. The lean meat is of a brownish mahogany color, and on being cut into has a peculiar sickening odor. Sometimes the superficial muscles have the natural pink red tint, but the deep seated muscles, and especially the intercostal muscles (those between the ribs), have the dark brown color and nauseous smell. 5. Disinfection and Disinfectants. — Carbolic acid is an absolute and perfect disinfectant. It not only destroys the odor but kills the virus of the disease. We advise all farmers and drovers who have reason to suspect that their cattle have been exposed to the infection, to sprinkle the substance known as " heavy oil," which contains about ten per cent of carbolic acid, abundantly about the yards where they are confined, and to put some carbolic acid into the water they drink, in the proportion of one part of pure acid, with thrice its own weight of sal soda, to one thousand parts of water. 6. The Disease is not Necessarily Fatal. — Several cases have recovered under our immediate observation, that have exhibited unequivocal indications of severe disease, at Providence, Communipaw and the National drove yards. In some instances the diseased cattle have been pastured where they have had access to salt marsh grass, for which they have exhibited a decided fondness, abandoning the upland pastures and confining themselves to the salt marshes, and it appeared to accelerate their recovery. In other instances, where such facilities could not conveniently be had, salt was liberally supplied and a recovery was manifest. Diluted carbolic acid used as a drink has appeared to act beneficially ; but we do not wish to speak positively with respect to these apparent remedies. One of the cattle which had been seriously diseased, but was convalescent, was slaughtered in our presence. The fat had nearly recovered the normal color ; the lean meat still retained much of the characteristic brown color of the disease. The viscera showed unmistakable marks of recent disease, but were rapidly healing. We barely allude to this most interesting disease in this place, leaving full details for description by our scientific associates. 980 Annual Report of New York 7. We have reason to believe that our Assistant Commissioners have been very faithful in executing our instructions. We hear from every point, that the move- ment and marketing of infected cattle is efl'ectually stopped. Our Assistant Commissioner, Dr. M. Mon-is, acting in conjunction with the Board of Health for the Metropolitan district^ has been indefatigable in devising and executing a series of measures which, it is believed, will eifectually protect the citizens of the Metro- politan district from the dangers of diseased meat. In fact, we have no doubt that the meat now sold in the markets of that district is far more sound and healthy than it was even before the outbreak of this disease. 8. The committee for scientific investigation under the Metropolitan Board of Health have caused an extensive series of researches, under the supervision of Dr. E. Harris of that Board, in regard to the chemical, microscopic and chief patho- logical characteristics of this disease, and also caused most accurate drawings to be sketched to illustrate the pathological changes in the several organs and tissues that are chiefly affected. These, when published, will present an exhaustive expo- sition of all phases of the disease, and give peculiar satisfaction to the public generally as well as to scientific men. M. K. PATRICK, LEWIS F. ALLEN, J. STANTON GOULD, New YoeEj September 5, 1868. State Commissioners. (C.) THE CATTLE DISEASE. ILLINOIS COMPLAINS OF THE ACTION OF THE NEW TORE AUTHORITIES — COMMIS- SION APPOINTED TO VISIT THIS STATE. On Monday last, says the Springfield (^III.^ Journal of September 2d, an infor- mal meeting of several of the citizens of this section interested in cattle and the cattle trade, was held at the ofiice of Colonel John Williams, in this city, for the purpose of devising some means for the protection of the shippers of stock to Buffalo, New York, and other points,. The committee addressed a letter to Governor Oglesby, and in accordance with the wishes of the committee, he appointed Messrs. Harvey N. Edwards and Edmund H. Piper as Special Com- missioners to proceed to New York to look after the interests of Western shippers of cattle. He also addressed a letter to Governor Fenton, of New York, in rela- tion to the matter. Below we publish the letter of the committee addressed to Gov. Oglesby, and other documents relating to the matter. The following is the letter to the Governor : Springfield, III., Monday, August 31. His Excellency Richard J. Oglesby : The undersigned having been appointed a committee, by a public meeting of some of the citizens of Sangamon county interested in the cattle business, to wait on your excellency as Governor of Illinois, and request of your excellency a semi- State Agricultural Society. 981 oflBcial power or authentic letter authorizing and empowering Harvey N. Edwards of Sangamon, and Edward H. Piper of Macon county, to proceed to Albany and Buffalo, in the State of New York, and there take into consideration, among the conflicting and clashing interests of the harsh speculators, the best cattle interest of the State of Illinois. There is reason to fear that the interest of Illinois will be sacrificed unless this matter is promptly attended to. Hoping you may give as strong a power as you have authority to do, we sub- scribe ourselves, most respectfully, S. H. JONES, JOHN WILLIAMS, W. H. HERNDON, Committee. Appointment of Special Commissioners. State of Illinois, Executive Office, P Springfield, Sept. 1, 1868. 5 7b all whom these presents shall come, greeting : Responding to the wishes of our citizens especially interested in preventing dis- ease among cattle, and in protecting the trade in and shipment of live stock from the State of Illinois to Eastern markets, as formally expressed in a resolution passed at a meeting of citizens interested in stock raising and shipment of cattle, held in Sangamon county, August 31, 1868, I do hereby appoint and commission Harvey N. Edwards, of Sangamon county, and Edmund H. Piper, of Macon county, as Special Commissioners, to proceed to the State of New York, with full power to inquire into and cooperate with the efforts made by the authorities of the State of New York, referring to and bearing upon the shipment of cattle from this State to the Eastern markets, and especially to petition the Executive authority of that State and the Special Commissioners or Inspectors to whom has been intrusted, under the laws of said State, the power to impose restrictions and limitations upon the trade in and shipment of cattle to Eastern markets, to so regulate and alter the same as not to hinder or embarrass oppressively the shipment of and trade in stock from the State of Illinois. In this respect due consideration will be given to prevent and suppress the disease or threatened epidemic among cattle. The Commissioners appointed by this authority have full power to enter into any arrangements necessary to a satisfactory settlement of all questions arising upon the subject of their appointment. In testimony whereof, I have hereunto set my hand and caused the great seal of the Sate to be hereunto affixed. Done at the city of Springfield, this first day of September, in the year of our Lord one thousand eight hundred and sixty-eight. RICHARD J OGLESBY. By the Governor : Sharon Ttndale, Secretary of State. Letter oj Gov. Oglesby to Gov. Fenton. State of Illinois, Executive Office, Springfield, Sept. 1, 1868. His Excellency Reuben E. Fenton, Governor of the State of New York, Albany : Dear Sir — I take pleasure in introducing to you, and recommending to your favorable attention, Messrs. Harvey N. Edwards and Edmund H. Piper, of this State, whom I have this day taken the liberty to appoint as Special Commission- 982 Annual Report of New York ers to visit your State for the purpose of making inquiry into the restrictions yonr authorities have deemed important and necessary to impose upon the trade in and shipment of cattle from this State to the Eastern markets, in consequence of an apprehended epidemic among cattle, commonly known as the Spanish or Texas fever. I will thank you, in behalf of the people of this State, for any assistance or suggestions you may be able to give these gentlemen, to aid them in securing the objects of their appointment . They have been instructed to present to you their authority, and to confer with you freely on the subject, in a spirit of entire good will, to the end that trade may not be unnecessarily restricted, and that both the consumer and shipper may enjoy the full benefit of as free trade as is possible under the circumstances. With high regards, I am. Governor, very respectfully, your obedient servant. E. J. OGLESBY, Governor of Illinois. (D.) Albany, Odoher 13, 1868. Dear Sir — In view of the ravages of the disease known as the Texas fever among cattle, and the inadequacy of the lavrs enacted by the several States for the repression of this and other kindred diseases, and the conflicting provisions of these laws, which have been disclosed since this disease has been prevalent, a general desire has been felt and expressed by farmers, drovers and the consumers of meat in several States, that a wise and efficient system of legislation should be adopted for the repression and prevention of this and other similar diseases in the several States, so that the laws should be harmonious, and adapted to mutual pro- tection. And it has been believed by nearly every one that has expressed an opinion upon the subject, that the best mode of effecting this object is by the assembling of a Convention of the Cattle Commissioners of the several States interested in the subject, who would represent all the varied interests of the pro- ducing and consuming States, and supply all the mformation necessary for the full elucidation of the subject, and whose duty it should be to prepare a draft of a law which should ensure the most perfect protection to all parties, to be recommended to the several Legislatures for adoption. And the Commissioners of the State of New York having been requested by the Commissioners of several of the States, and of the Dominion of Canada, to take the initiative in calling such Convention, We do, therefore, recommend that a Convention be held in the city of Spring- field, in the State of Illinois, on Tuesday, the first day of December, 1868, at twelve o'clock at noon of said day. The object of such Convention is to consider ,the pathology, symptomatology and history of the Texas cattle fever, and other infectious and contagious diseases to which cattle and other stock are subject, and the best methods of preventing the . spread of such diseases with reference to the interests of the producer and con- sumer, and also to consider the sanitary requirements of the community with reference to the feeding and rest of the animals in transitu^, and to the best methods of slaughtering and preparing them for market. The Convention will also prepare a draft of a law which shall provide for the accomplishment of these objects, to be submitted to the Legislatures of the States represented therein for adoption. Each State and Province to be represented by three (3) Comnussioners. State Agricultural Society. 933 The Cattle Commissioners of the State of Illinois are requested to secure a suitable place of meeting for the Convention. His Excellency the Governor is hereby respectfully requested to transmit copies of tiiis call to the Governors of the several States, where such Commissioners are not already appointed, with a request that they would appoint such Commissioners to represent their States in such Convention. M. R. PATRICK, L. F. ALLEN, JOHN STANTON GOULD. (E.) SUGGESTIONS TO FARMERS. 1st. When the disease makes its appearance in any neighborhood all the owners of neat cattle should make a point of examining each animal every morning. The chief points to which their attention should be directed, are the fol- lowing: (a.) The head. Whether it hangs down ; whether the eyes are dull and staring j whether the horns are hal or cold (6.) The coat. Whether it is rough or smooth. (c.) The urine. Whether it is a dark red or black. (d.) The hind legs. Whether the gait is staggering, and whether the knees seem weak. (e.) The dung. Whether it is natural or otherwise, and especially whether the animal arches its back and makes ineffectual efforts to dung. (y.) See if there is any drooling of frothy matter from the lips. (g'.) If you have a fever thermometer, insert it into the rectum (bung), let it remain until the mercury ceases to rise, then note the temperature. If it is 102*-* Fahrenheit, and any of the above mentioned symptoms are present, you have good reason to suspect the presence of the Texan cattle fever, and the probability is increased by every additional degree of temperature. (A.) It is very important that the dates be carefully observed of all the symp- toms connected with the disease, and experience has shown that memory is very untrustworthy; by all means, therefore, let the above facts be clearly written down as soon as possible after the observation is made. (i.) Shut up all suspected cattle in a lot or building by themselves, so that no other cattle can have access to them or their droppings. (j.) Send word as soon as possible to the nearest Assistant Commissioners, of the suspected cattye, by telegraph, if one is accessible. 2d. Means of prevention. (a.) When the disease is present in any neighborhood, every owner of cattle should be provided with a barrel of heavy coal oil, which contains from eight to twelve per cent of carbolic acid, and a quart of liquid carbolic acid containing ninety per cent of the acid. The latter is miscible with water; the former is not. (6.) If the suspected cattle are kept in a building, let the floors be sprinkled with heavy oil, and especially let it be sprinkled on the droppings as fast as they 934 Annual Report of New York are made. The woodwork of their stalls, and behind their stalls, should be covered with this substance, spread on by a common whitewash brush. The heavy oil may be sprinkled on the floor with a common watering pot. (N. B. — These articles are furnished by the Warren Chemical Manufacturing Company, No. 4 Cedar street. New York.) (c.) If the suspected cattle be herded in a yard or small pasture, let the drop- pings be sprinkled daily with heavy coal oil. (rf.) Remember that strict isolation is the chief means of safety. Let no strange animal come upon the place. Let no suspected animal go upon the public road, or have access to running water to which other animals go. The dung and urine of diseased animals are the chief means of propagating the contagion, and it is known that it is often diffused by the dung which adheres to the shoes of attendants. A box containing slacked lime or ground plaster, well saturated with the heavy oil, should be kept near the diseased animals, and all persons when leaving the vicinity of such animals, should carefully rub their shoes in the powder in the box. , 3d. Curative means. There is no certain cure for the disease. Some animals get well without any medicine, others seem to have been benefited by feed- ing in a salt marsh and on green corn. (a.) In case you have the liquid carbolic acid of ninety-five per cent which will mix with water, drop enough of it into a part of water to give a slight taste to the water, and let the diseased cattle drink of it twice a day. (6.) If you have nothing but the heavy oil, mix three ounces of soda with it, which will render it miscible with water, and put the mixture into a quart of water ; pour enough of the mixture into a pail of water, and let them have two pailsfull a day. (c.) Let the sick animals drink freely of water, as they are generally thirsty, and place salt where they can lick it whenever they are disposed to do so. (d.) With regard to food, follow the advice of the medical practitioner. (N. B. — If carbolic acid cannot be obtained, dissolve two pounds of sulphate of iron — green copperas — in a gallon of water, and use the solution as directed for the heavy oil.) Let aU animals that have died of the disease, be buried at least seven feet deep. Cover them with a barrel of lime, then replace the earth. EEPORT UPO^ INVESTIGATIONS CONCBBNING THE TEXAS CATTLE DISEASE, To the Sanitary Committee of the Metropolitan Board of Health: The investigations that were committed to your direction in regard to the infections disease in beef cattle, by the Metropolitan Board of Health, are now so nearly terminated that it becomes a duty to report to you the results which have been reached in the inquiries that you placed under the writer's supervision. In presenting this report, the superintendent of the work feels that it is due to 3'our committee, and especially to the medical officers who have been engaged in these researches, to state that this duty was undertaken at a period when each of us was burdened with an unusual amount of work, and that whatever may appear in the report to be incomplete and too meagre in the record of details or circumstances concerning these labors, might justly be charged to the excessive demands that were made upon our time, as well as to the new and difficult nature of the investigations. And, in addition to this, it is proper to remark, in this introductory para- graph, that these investigations were at first undertaken and subse- quently carried forward — step by step — wholly from a consciousness of the duty which was due to the Board of Health, and by the Board to the public; and that if the Board could have found the means to employ more aid in this work, your committee would now be able to present at the conclusion a more complete report. The exigency was instantaneous, and the duty of making an investigation in the interest of the public health and of sanitary knowledge was obvious; but until the nature and extent of this remarkable infection in the herds that supply our markets had 986 Annual Report of New York become known, it was not certain that the results of these investi- gations would warrant the scope and cost of them unless the labors were voluntarily assumed by medical men who were already in the Board's service. The possibility of prosecuting any exact and trust- worthy scientific investigations depended, practically, upon the wil- lingness of medical officers to make considerable sacrifices of time and toil; and it is due to them and to the Board that the fact should here be stated, that the hope of making these investigations con- tribute something to hygienic and medical knowledge, particularly in regard to pestilential fevers, cojitinued to inspire and sustain these labors after all danger of the sale and use of the diseased beeves had passed. The medical profession and sanitary authorities will bear witness that this hope has not been disappointed. Practical difficulties in conducting such investigations unfortunately deter Boards of Health and individual observers from attempting to make their inquiries systematic and comprehensive; and it has been found impossible to make all branches of these inquiries in New York as complete as the requirements of exact investigations demand. This is especially true of the medical observations upon symptoms and tests of the disease in its various stages. But what- ever observations were possible during the brief last stage of the disease, are put on record in this report. Great difficulties were experienced by the committee of investigation in reaching the diseased animals, and providing for the killing and dissecting of them. So sudden was the onset of the obvious or fatal stage of the malady that this circumstance is found to have efiectually defeated the attempts of many of the best sanitary officers in other places. It has been easy to find and examine dead cattle, but diffi- cult to bring medical observation to bear upon the living, and upon the condition of the organs and tissues at the moment of death, and before any post mortem changes could occur. It is this latter feature of success that gives special value to the results reached in the Metropolitan district. The requirements of the present advanced state of pathological and hygienic knowledge demanded that whatever investigations we undertook in this matter should extend beyond the merely super- ficial and obvious phenomena and appearances, and that, so far as possible, the methods and purposes of each line of inquiry should be exact, searching and strictly in accordance with the requirements of the sciences whose aid should be invoked in the work. It was also known to us that the Metropolitan market being the natural State Agricultural Society. 987 terminus of the great railroad route for such herds of infected beeves as might be hurried forward by the unfortunate holder of them — true to " the commercial instinct to make whatever salvasre he can," when an incubating poison threatens inequitable destruc- tion to his cattle and his fortunes — the opportunity and the public duty of making faithful investigations would probably be greater in New York than at any other point east of the prairies, which had become the temporary source of the disease. Experience soon confirmed the truth of this opinion. Lest the nature of the sanitary questions, which were of pre- dominant importance in these investigations, may be misconceived, by readers of this report, the fact must here be stated that no medical officer presumed that the Texas cattle disease would repro-. duce itself in the human family. But it was believed, and it is true, that the rapidly and utterly putrefactive efiect of this disease in its fatal stages, clearly pronounce upon the unfitness of such dying cattle for human food. This view of the subject did, at first, very energetically animate the endeavor which the Board of Health put forth to prevent such dead and diseased beeves from being sold in the markets. But it must not be supposed that the Board's officers were ignorant of the fact that some of the most deadly viruses, even that of the rattlesnake and the woorara, may be taken into the human stomach without obvious harm. The point aimed at was attained, namely, to prevent the diseased and dying beeves from being used for food. The means employed by the Board in attain- ing this result, were universally understood and appreciated. The press and the people throughout the Metropolitan district, and wherever the diseased cattle were seen, emphatically sustained and commended this action of the Board. Herdmen and agriculturists also gave their willing testimony and obedience to the mere recom- mendations of the sanitary officers, and are now sincerely grateful for the practical results of the sanitary regulations and the scien- tific inquiry relating to the disease. In pursuing these labors, the Board's committee has sought information from every available source throughout the country, and has enjoyed the most hearty cooperation from every class of observers of the disease; and it seemed very desirable to make investigations, upon as broad a basis as possible, of general informa- tion concerning it. Such a basis has given a certain tone of trust- worthiness to the Board's work, that is justly a subject for the committee's gratitude. Great care has been taken to examine and 988 Annual Report of New York analyze the mass of general and special evidence that has, by the kindness of correspondents and co-workers, come into our hands. The conclusions that are reached in this report are in harmony with all that is logically deducible from that body of evidence, though we have depended upon our own observations and the collateral researches that grew out of them. ; Could the medical officers who have pursued these inquiries now consult their personal preferences, they would defer the presentation of this report until there shall have been a free interchange of the various reports by State Commissioners; but the request that this report shall be submitted without such delay, is obeyed with alac- rity, because both the Board of Health and the State Commissioners for the prevention of cattle plagues in New York, have expressed a desire to make immediate use of the information contained in this report. But in thus hastily closing the report, it must inevi- tably be marred by defects that will need to be corrected hereafter. The culture experiments upon the cryptogamic or fungus element found in the blood and bile of the infected cattle, are still in pro- gress under the skillful hands of Dr. Stiles, the deputy registrar of the Board of Health, and of Prof. Ernst Hallier, of Jena, and will be continued as long as they may deem it desirable. These and some other incidental inquiries, while they may eventually throw light upon the causation and concomitants of the disease, do not in any way postpone the practical conclusions and sanitary measures which State authorities need to adopt. And there is much reason to believe that every branch of the investigations which have been commenced under the approbation of your com- mittee and of the Board, will ultimately lead to a correct knowledge of the disease, and to the utter extinction of it. If, in attaining that result, it is found that important truths are established con- cerning the cause and prevention of certain pestilential diseases in the human family, the public duty of exact inquiry into the causes and prevention of all epidemic and epizootic diseases will be prac- tically illustrated. This ultimate object of medical inquiry will not fail to be attained if sanitary officers will, in the discharge of their duties as guardians of human health, carefully observe and investigate the nature and causes of the infectious plagues that occur in those useful classes of animals which the beneficent Creator has given to man for food and service. The people who require safeguards against insidious sources of disease, will share with the State Agricultural Society 989 herdman and the farmer such immediate and obvious benefits of the sanitary investigation and restraint of cattle plagues, as will fully repay the toil it costs, and in the end, the total results will be found added to the sum of human happiness and healthy life. E. HARRIS. New York, December Zlst, 1868. PLAN OF THIS REPORT. I. A consecutive account of events connected witli the appearance of the Texas Cattle Disease, and of the procedures which were taken, thereon. II. The Records of the Sanitary Inspector of the Board and Assistant- Commissioner of the State, concerning the herds of Diseased Cat- tle that have come into the Metropolitan District. — Dr. Moreau Morris' Special Report. III. Statement of the Results sought and reached in Correspondence with other observers. IV. Statement regarding the chief objects of exact Scientific Investiga- tions, the nature of the Methods adopted for attaining them, and the Results attained. V. Special Report, by R. Cresson Stiles, upon the Pathology of the Cattle disease, and upon the Microscopical Researches for ascer- taining the Nature and Effects of the Contagium, or Cause of this Disease. VI. Report of the Results of Chemical Analysis of the Blood, Bile, Urine and Liver, obtained from the Diseased Cattle. By Prof. C. F. Chandler. VII. Explanations of the Illustrations. VIII. With what well described diseases is this Texas Cattle Disease allied ? IX. Remarks upon the New Facts and Demonstrations added to Physio- logical and Pathological Knowledge by these Investigations. X. Conclusions. I. ACCOUNT OF EVENTS AND PROCEEDINGS. DISCOVERY OF THE DISEASE IN THE HERD YARDS. Early on the morning of August 8th, the Eegistrar of the Board of Health obtained information from a member of the staff of the daily Tribune, that there was believed to be a herd of diseased and dying cattle at one of the two great herd yards near Jersey City. Certain unusual events in the progress of sudden and fatal diarrhoeal disorders, in various parts of the city of New York, in the previous ten days, induced us to make a personal investigation concerning the reported herd of infected cattle. Proceeding to the abattoir yards at Communipaw, the fact was ascertained that there were then remaining alive upon the grounds there, one hundred and forty-one bullocks that arrived the previous day, consigned to J. T. Alexander, Esq.," Mr. Fitch, agent, and out of which there had died, or been sacrificed, because dying, two hundred and twenty-four bullocks during the trip from Homer, 111., to this eastern terminus of the route. Having ascertained the fact that these cattle had been shipped from Central Illinois, in apparently perfect health, only eight days previously to the visit here mentioned; that the care of that herd train had been quite as good as is usual upon the railroads; that the disease began to be noticed about the second day after departure upon the route, and that between Central Ohio and the time of departure of that cattle train from Pittsburg, a period of four or five days, no less than one hundred and fifty-nine of the herd died of the disease, permission was asked and granted for examining the residue of the herd then in the yards at Communipaw. About fifteen out of the hundred and upwards that were seen, appeared to be sick, and upon testing the temperature of two that were approached, the mercury in the self-registering thermometer went up to one hundred and five, and one hundred and six degrees respectively. This observation not only comported with the circumstantial history of the events above related, but of itself alone this remarkable excess of animal temperature, in the absence 992 Annual Report of New York of any evidence of inflammatory disease, and with the pulse rapid and flickering, the secretion from the kidneys copious and blood-stained, and the gait and posture tremulous, fully warranted the conclusion, that the disease there witnessed for the first time at our herd yards, must necessarily be of a pestilential nature, and that any virus or morbid poison which could cause such a malady, was deserving of the most exact and careful scientific inquiry. The peculiar circumstances of the season which had made it necessary to watch very vigilantly for all removable and special . causes of acute and fatal diarrhoeal disorders among the people of the city, rendered it a duty to undertake a careful examination of the viscera and fluids of the dying bullocks, to ascertain what dis- eased conditions they might present. Accordingly, the Registrar of the Board requested the president of the abattoir to allow the medi- cal officers an opportunity to make such examinations at the earliest convenient hour. It was earnestly advised that no sick cattle should be sent over to the city markets, either alive or dead.' Mr. Payson, the president, took an enlightened and proper view of all questions connected with this matter, and remarked that it would be well to have the Governors of New York, New Jersey and Pennsylvania take such action, in concert with the Governor of Illinois, as might lead to the proper investigation of the local sources of the disease, and to a proper restraint upon the transportation of cattle subject to it. The course pursued by that gentleman during the evening of the 8th and the morning of the 9th of August, proved how judiciously and honorably he undertook his own duty in regard to the sick cattle. To this we will presently refer again. During the afternoon of the 8th, Hon. Geo. B. Lincoln, President of the Board of Health, in concert with Hon. Commissioner Manniere, decided to have the herd yard, within the limits of New York city, inspected under the direction of the Sanitary Superintendent, Dr. E. B. Dalton. The circumstances and results of that inspection are mentioned in the proper place in the special report of Sanitary Inspector Dr. Morris, Upon the return of the Board's officer. from Communipaw, in the afternoon, it was deemed expedient to send dispatches to the Governors of New York, New Jersey and Pennsylvania, giving them information, and suggesting such action on their part as should at once restrain the movement of all sick and infected herds. Consequently, the president of the Board sent telegraphic dispatches to Governor Fenton, at Albany; Governor Ward, at Newark-, N. J., State Agricultural Society. 993 and Governor Geary, at Harrisburg, Pa., informing them of the sick cattle, and suggesting the sanitary inspection of the transport trains and herd yards on the railroads that enter these States from the West. The several Governors replied that the desired action would be taken. There doubtless may have been some persons who thought that such promptitude of official inquiry and action was unwarranted by any possibilities of peril, and by all lessons of experience; and, that there may occasionally be found a man, who still believes that it would have been wiser to wait, and see the results of the pestilence, and of the use of the diseased beeves as food, is not unexpected. But the public would not have excused the sanitary officers for any such stolidity and indifferent delay, nor does experience warrant the belief that it would have been safe or jDrudent to have delayed action. Indeed, it chanced to be true that the officer who first moved in this duty for the Board of Health, knew the history of epizootic pestilences too well to admit of hesitation and delay.* ♦The following extract from an editorial leader in the London Times of August 28th, will now be perused with advantage, for it conveys the true principles regarding such duties, in clear and forcible language : "As the home of the rinderpest is on the steppes of Russia, ^o this American plague comes from the vast plains of Texas. Now, it appears that during last May and June some fifteen thousand cattle were slowly driven from Texas to Illinois, feeding on the prairies as they passed. «««««»«• From Illinois, the disease spread to the adjoining State of Indiana, where thousands of cattle are still said to be dying of it, and to the city of Chicago. The next step in its progress was, that some Illinois cattle were dispatched by railway to Pittsburg, ia Pennsylvania. Before reaching Pittsburg a large proportion of them perished, and others died in the Pittsburg drove yards. Thence some apparently healthy animals were sent by rail to New York, but the fatal symptoms appeared after their arrival, and within tea or twelve days after the appearance of the cattle at Pittsburg, the disease had penetrated to the northern part of New York State. The history of the development of the disease, therefore, is complete. From Texas it is tracked over the prairies tu Illinois, and thence it is followed over railways to the great towns of the West. With us, though the course of the rinderpest is sufficiently established, there are generally some doubtful links in the chain of communication, but in this instance every step is discernible. "The gentlemen who thought it a fatal objection to a precautionary measure that it might slightly raise the price of meat in the London market, may, perhaps, accept instruction from the fact, that on the appearance of this disease, the supply of beef in the msirkets of New York and Chicago had fallen off at least one-half. They may see that, from fear of a slight and very doubtful disadvantage, they would have exposed us to the certain peril of an occasional meat famine. This example may also give us, occasion to reflect, that at least in the present state of our knowledge, we are quite unable to rely oh special acts of precaution against the introduction of a contagious disease. Here is a disease, not less fatal than the rinderpest, of which we have only just heard; and, besides this, its approach is so sudden and so subtle as to leave no time for exceptional measures. Cattle apparently healthy are dispatched to New York, and within three days after their 'Ag.] 63 994 Annual Report of New York THE FIRST POST MORTEM EXAMINATIONS. The next day, Sunday, August 9th, the president of the abattoir informed the Board of Health that all the surviving bullocks of Mr. Alexander's infected herd were to be slaughtered and sacrificed at the fat-rendering tanks, and he invited the officers of the board to be present and make whatever examinations they desired. This invitation was accepted, and during that afternoon the officers in attendance witnessed the slaughter of a large number of the herd, and made minute examination of the viscera and fluids of three of those that were most diseased. The record of these and all other post mortem examinations of cattle will be found in the proper place in a subsequent section of this report. But we would here remark that the excessive temperature of the blood and viscera of the sick bullocks immediately upon the slaughter was so uniform and striking as to confirm the opinion that had been expressed by the Registrar concerning the significance of this fact in regard to the pestilential nature of the sickness; yet in these first exami- nations there was so great an amount of evidence of other kinds, and which required the analysis of the microscope, and of the chemist, that arrangements were immediately made to have the mor- bid specimens so examined by Dr. E. Cresson Stiles, the Deputy Registrar of the Board, an acknowledged authority in pathological and microscopical researches, and by Professor C. F. Chandler, the chemist to the Board. The subjoined note from Dr. Stiles gives the first result he reached in the microscopical examinations which he made of the specimens obtained on the 9th and 10th of August: arrival, they have given birth to a malady which may destroy all the stock in the State. That is the danger to which we are exposed the instant we relax our restrictions. Inspection might some day fail to detect the germ of disease in half a dozen animals, and the cattle of as many counties might be decimated in a month. Our knowledges^is not sufficiently extended, our means of information not suflSciently complete, our methods of observation not sufficiently subtle, for inspection to offer any sufficient security. It is somewhat singular that we should only now be learning to what subtle and contagious diseases our most valuable stock is exposed. Like other knowledge, this has probably been lost from mere want of due records. If the past history of the diseases of mankind had been preserved for us, medical science might now be in a very different position. This disadvantage will scarcely be allowed to check our progress for the future. The New, as well as the Old World, will yield experience, and we think we may fairly expect from our men of science that, with their means of observation, they will materially advance eur control over the conditions of health. At all events, such an example as the present deserves the utmost attention, and we shall await with the greatest interest the further history \\ Stiles, the Deputy Registrar, for the pathological researches which were required, all the good purposes and desire for thorough investigation of the essential nature, causes a morbid phenomena of the cattle plague would have enabled the board and its medical officers to add but very little to the stock of useful knowledge. The Registrar states this fact with gratitude, and without in the least depreciating the value of any labors performed by other officers of the board. This labor of Dr. Stiles has been continued from the 9th day of August to the 1st day of December, the first being the com- mencement of examinations in Mr. J. T. Alexander's infected herd [Ag.j 64 1010 Annual Report of New York at Coramunipaw: and the last being an examination of morbid specimens from two diseased Texas cattle that were taken ofi' a train at Buffalo, and carefully dissected by Assistant Commissioners Morris and Mackey, in the presence of the State commissioners. Bringing to these patient researches a well trained mind, with excellent experience and skill in the analytical study of healthy and morbid conditions of the animal organism, Dr. Stiles' aid in our investigations has been of the most indispensable character. And it must be regarded as particularly fortunate that in the absence of means for employing a special corps of anatomists and pathologists, the Board could obtain and use such skill as that of the gentleman here mentioned. THE AID OF CHEMISTRY IN THE INVESTIGATION OF THE DISEASE. PROF. C. F. CHANDLER'S LABORS. The excellent example of the Royal Commission in England for investigating the rinderpest in 1865-6, warranted the hope that analytical chemistry might bring out more definite results from the Texas cattle disease than had been attained even in the English researches. But as we were dealing with a blood disease, that had a much longer period of incubation of its infectious cause than the rinderpest has, and which also produces very decided alterations in the proximate and elemental constitution of the liver and some other viscera, it was thought best to submit the blood, bile and urine to the most exact analysis, in accordance with plans somewhat different from those which Dr. Marcet, the chemist to the rinderpest commission, pursued. Prof. Chandler has sufficiently explained the methods he pursued, in a note appended to the tabulated results which we present in this report. Very great care was exercised in the taking and sealing of morbid specimens for chemical analysis, and the aid of chemistry was especially invoked in the cases that most emphatically declared the symptoms and uncomplicated phenomena of the disease. Wherever it was practicable. Prof. Chandler attended in person at the post mortem examinations, and with his own hand took the spe- cimens and sealed them for his laboratory. In all cases the analyses were made as soon as possible after the specimens were taken. Out of the whole number of these analyses, Prof. Chandler has selected for tabulation in this report only those in which his success in the entire process of treatment was most thoroughly perfect and unequivocal. By referring to the section in which State Agricultural Society. 1011 these results are tabulated, it will be seen that there are fourteen (14) specimens of blood, nine (9) specimens of bile, four (4) of serum from the abdominal cavity (cases in which ascites and copi- ous effusion had occurred), four (4) analyses of urine (black water), and four (4) analyses of the liver. The exceeding nicety and skill which are required in the analysis of blood and bile, were appreciated and provided for by Prof. Chandler and his very skillful assistants in the laboratory. And, notwithstanding we did not at first venture to hope for very posi- tive results from chemistry to aid in the pathological investigation which the Sanitary Committee of the Board of Health required to be made, it now is found, in the final summing up, that almost any other element in the pathological study could be spared or omitted — microscopy alone excepted — rather than to now omit the results that chemistry has independently contributed. We say independently, because the chemist was requested to ascertain all the essential constituents of the specimens submitted, to him, and permit no errors or loss in his quantitative estimation, regardless of any ideas he might entertain concerning the disease. We have requested the Professor to append the results of the analysis of healthy bullock's blood, as analyzed in his own laboratory, and also to place at the foot of his table of analyses the mean of all the results in the analysis of blood from fourteen healthy bullocks, also the result obtained by Wm. Marcet, Esq., for the English Commission in 1866. It is hardly necessary to state to medical men, but it must be remarked for non-medical readers of this report, that the chief objects to be attained in all these analyses by the chemist to the board were: 1. To ascertain what changes in the proximate elements of the blood are found to characterize the disease, par- ticularly as regards waste and deficiency in its solid constituents, and to point out what elements are so afiected; 2. To ascertain the state of the serum found in cavities of the diseased cattle; 3. To ascertain in what respect the bile and the urine difiered from those fluids in healthy animals; and 4. To ascertain the actual chemistry of the liver, and particularly as regards the percentage of fat in it in the chronic cases of the disease. In all this work chemistry is the aid and verifier of deductions reached by the different methods of microscopy and medical observation. Finally, in regard to the merit of Prof Chandler's labors in this matter, we feel warranted in stating that for accuracy and defiuiteness, we know of no other 1012 Annual Report of New York series of analyses of bullock's blood, and of the other elements of the body in disease, that exceed the accuracy of the results which the chemist to the Board now contributes to this report. THE SKETCHES OF MORBID ANATOMY BY MR. KOEHLER. This work was begun on the 10th of August, the artist being conveyed to the place of slaughter, and, in all cases, when possi- ble, completing his sketches in colors immediately upon slaughter and dissection. With but one or two exceptions, the specimens that are used to illustrate the chapters on pathology in this report, were sketched in this manner when perfectly fresh and before any post mortem change, even in appearance, could have occurred. The artist was strictly ordered to permit no deviation from nature in his sketches and colors. He has executed his task with exceeding faithfulness. This artist, Mr. Robert Koehler, enjoys a just reputation for rare excellence in regard to truthfulness in anatomical delineation and coloring. His professional life having been spent in this kind of work, and Prof. Karl Bock's celebrated Atlas of Human Anatomy having been illustrated by his hand before he came to this country, he has continued to receive in New York the same contidence and patronage of the anatomists and pathologists that he enjoyed at Leipzig, where he was the assistant to Prof. Bock. As the value of these colored sketches of morbid anatomy of the Texas disease in cattle must depend upon their truthfulness and the freshness of the specimens they are made to illustrate, this introductory note is due to the Committee's report, and to Mr. Koehler, the artist. SUMMARY OF THE EVENTS AND THE PROGRESS OF INVESTIGATIONS IN REGARD TO THE DISEASE. As the details of all that relates to the arrival, inspection an'd care of infected cattle, are embodied iii Assistant Commissioner Morris' report in the succeeding section, we need only state here, that in the prosecution of the Committee's duties in regard to the diseased cattle, it was necessary to give all possible aid to Dr. Morris in providing for the slaughter and post mortem examina- tion of the cattle he condemned and ordered to be killed, or that were permitted to Ihiger in quarantine until they died. It has also continued to be necessary, until December 1st, to maintain extensive correspondence to ascertain the history of herds and their movements connected with the manifestations of the disease; and it has also daily been necessary to take counsel together upon the results of these inquiries and the new events in the progress State Agricultural Society. 1013 of the disease. Happily the contagious principle upon which the disease depends for its propagation in the North and "West, has proved to be capable of repropagatiug itself only in a very limited and subtle way; but the very circumstances of this subtlety of the contagium has rendered it the more necessary to push on our inqui- ries and experiments the more assiduously while opportunity has been aflbrded. All of this labor may be briefly summed up as follows: 1. Every example of the disease within the reach of the com- mittee of the Board of Health, or Assistant Commissioner Morris, has been promptly investigated; and, if the bullock was not recovering, the slaughter for post mortem examination of the animal was provided for; or, if already dead, the proper expert inspection was made by two or more officers of the board. Assistant Commissioner Morris being one of them. The total number of infected cattle and diseased carcasses so inspected and examined, between the dates of August 9th and December 1st, being between two hundred or three hundred. Upwards of forty (40) infected bullocks have been slaughtered and very minutely examined by this committee in a definite and scientific manner. 2. Unceasing effort has been made during a period of nearly four months to discover and inspect every animal sufiering from the Texas disease within the Metropolitan district. Assistant Commissioner Morris during this period has inspected many thou- sand cattle, and he sought the counsel and aid of this committee daily. 3. All cattle found dead or dying from unknown or suspected causes in the city of New York, have been carefully inspected, and their internal organs examined under the direction of this committee. 4. By an arrangement with the Superintendent of the New York Rendering Company, a corporation that has the contract for gather- ing and disposing of all dead animals from the city, the dying and dead cattle that were daily conveyed to the rendering dock, were reported and examined. In like manner all information received by the superintendent there was at once communicated to this com- mittee of the Board of Health. 5. Whenever a creature was found with this disease, the symp- toms and progress of it were reported twice daily, and if brought to slaughter, all necessary preparations were made beforehand for taking and preserving specimens instantly upon killing the animal. No specimens were deemed suitable for analysis and for the artist's sketching unless obtained immediately at death, and brought under such study without delay. 1014 Annual Report of New York 6. A series of experiments to test the morbid effects of bile, liver and muscular tissue, used with food, was made under the care of Dr. F. J. Randall, an assistant sanitary inspector connected with the Registrar's office. Dogs, rabbits and mice were the animals experimentally fed in this way. Other experiments also were made to ascertain the modes in which the infectious principle of the disease might be made to produce its morbid effects in healthy animals. 7. A series of special inquiries was made to ascertain the exist- ence and nature of this infectious disease in freshly arrived Texas cattle; also preliminary inquiry upon this point, by extensive cor- respondence, was made before any of the Texan stock came under inspection of this committee and the Sanitary inspectors. The first of our inquiries upon this subject were addressed to Dr. J. H. Ranch, the sanitary superintendent of Chicago, and Prof. John Gamgee. After the lapse of about ten daj^s, both these gentlemen replied by letter, the former from the Chicago stock yards, under date of August 22d, and the latter from Kansas City, under date of August 23d, assuring us that the disease had been found by them, respectively, in the Texas cattle at those places. Subsequent opportunities in New York enabled the Sanitary inspectors to verify the correctness of the conclusions that had been communicated to us by Dr. Ranch and Prof. Gamgee. 8. Experimental culture (by " planting") of the spores of the morbid bile and blood of the infected cattle was commenced in September, and continued until December, for the purpose of ascertaining the true nature of the fungus from which the spores are derived, that is, to ascertain the botanical characteristics and parasitical history of the cryptogam to which the spores that are found in the blood and bile belong. The chief results of these experimental researches are concisely presented by Dr. Stiles in the second part of his report. 9. By correspondence and inquiry, effort was made to ascertain if the contagium of the Texas disease is propagated, even occasionally, by the native Northern cattle; and, quite unexpectedly, contrary at least to very positive assertions as well as to the general rule, instances were found in which the disease has been transmitted by native cattle. 10. Finally, the evidences of health and disease have been very carefully studied by Dr. Morris ever since his labors commenced in August, and by several Sanitary inspectors during the latter part of Autumn, and, as far as time would permit, every week since the Texas cattle disease appeared in the vicinity of New York. State Agricultural Society. 1015 n. REPOET ON SANITARY INSPECTION, REGULATIONS AND MEDICAL OBSERYATION. BY MOREAU MORRIS, M. D., Sanitary Inspector M. B. H., and Assistant-Commissioner of the State. Records Concerning Herds of Diseased Cattle that have come into the Metropolitan District, or under the Observation of Sanitary Inspectors of the Metropolitan Board of Health. To the Committee of the Metropolitan Board of Health, for investigating the Texas cattle disease, and the State Commissioners for the prevention and control of cattle plagues : Gentlemen: For more than four months my time has been exclcusively occupied with the observation, inquiries and sanitary regulations relating to the Texas cattle disease within the Metro- politan district, and wheresoever you directed my services. My report to you consists mainly of records. They are records of events so interwoven with matters of historical interest concern- ing this disease, that it seems advisable to present this statement of my labors so consecutively as to be both complete in itself, and entirely convenient for reference from other branches of your reports respectively. It seems impossible in reporting to you the details and results of these labors so to discriminate the par- ticular duties that were performed by me as an officer under the Board of Health, from the duties which I daily performed under the authority of the State commissioners and the special statutes relating to the cattle plagues, that it would be difficult for me to make a full and correct report, concerning either the former or the latter class of my duties, without at the same time actually recount- ing the entire history of events during this period of service; con- sequently this report is respectfully addressed both to the Board of Health and to the State commissioners. Were I to report to your honorable boards separately, the two reports would be in every respect identical in substance. In making this report, the following order will be observed: 1. The date and leading events in the duties of each day. 1016 Annual Report of New York 2. The record of whatever observations were made in the inspec- tion of cattle, together with an account of whatever sickness occurred among the herds from day to day. 3. Such arrangement and classification of particular portions of these records as may be necessary for the convenient study of events connected with the disease. 4. Observation upon other kinds of diseased cattle in the New York beef market. 5. Remarks upon evils which were restrained and controlled and upon sanitary measures concerning cattle and beef in the New York market. 6. What is designed and what should be accomplished by sani- tary inspection and control in regard to animals and meats offered in the Metropolitan markets. 7. What conclusions and results have been reached in my obser- vations and experience in this work. So far as the legal authority and influence of the Board of Health could be made available to meet the exigencies which occurred in consequence of the Texas cattle disease, the Board promptly exericsed that power and wielded that influence. The State com- missioners for the suppression of cattle plagues have acted in the same spirit as that displayed by the Board of Health. But it is a fact which seems to demand the attention not only of your commissions respectively, but also of the chief executive and the legislators of the State, that all the powers and the methods for procuring the needed sanitary inspection and control of market, cattle and meats, have been only temporary expedients. Systematic and skilled inspection, under adequate laws of the State, should be established as an essential branch of sanitary government. On the evening of the 8th day of Aug., 1868, 1 received the follow- ing letter, directing immediate investigation and report upon the facts. [Copy.'] E. B. D ALTON, Sanitary Superintendent Metropolitan Board of Health: Dear Sir — Dispatches from Chicago indicate the existence of a cattle disease in the West, and intimate that some of the infected stock are on the way to this city, if, indeed, they are not already here. In the absence of other commissioners, Mr. Manniere and myself agree without delay one of your inspectors should be directed to repair to the districts where Western cattle are received, and to ascer- tain and report all the facts. It will require tact in the performance of this duty, doubtless, to find out anything in relation to this matter, as the interests of the butchers are all against any development of facts showing the presence of diseased eattle. Yours truly, (Signed) GEO. B. LINCOLN, President. ' State Agricultural Society. 1017 Upon this letter from the President of the Board of Health was the following indorsement: Office Sanitary Superintkndent, ) Metropolitan Board op Health, Jlugust 8, 1868. ) Respectfully referred to Sanitary Inspector Morris for immediate investigation, and report in writing or by telegraph if any facts be discovered which require it. (Signed) E. B. DALTON, Sanitary Superintendent Metropolitan Sanitary District. I immediately visited the National drove yards, located at One Hundredth street, between Third and Fourth avenues. There were but few cattle present, and found none sick. The next morning visited the same yards again, and finding none sick, I joined the president of the Board, Drs. Harris and Stiles, in a visit to the abbattoir at Communipa w, where Mr. J. T. Alexander's infected cattle, which Dr. Harris had examined the previous day, were beino- slauo-htered and thrown into the renderinsr tanks. Here we found that one hundred and forty-one of Mr. Alex- ander's herd, which had left Homer, 111., on the evening of the last day of July, were being sacrificed at the rendering tanks in ordei* to avoid all risks and public injury that might result from keeping them for sale in the market yards. A large number of these cattle were evidently sick, as indicated by the following symptoms: Attitude: An arched or roached back; head carried low down; ears drooping; ej^es staring, with a dull, glassy appearance; gait tremulous, and staggering in the hind quarters; the foeces hard, streaked with blood; urine copious, and bloody in appearance {Jimmatuna)] pulse, in the most marked cases, was found to be at about eighty, thready, and in some of the animals almost imper- ceptible; the respiration, in one marked case, was found forty in the minute — auscultation of the chest furnished no abnormal signs; the temperature of the rectum, in some of the most diseased, was found to be one hundred and seven degrees Fah. A bullock in the last stage of the disease was slaughtered for thorough dissection, which was made by the medical gentlemen present. The following morbid appearances were noticed: The gastro - intestinal mucous membrane was marked b}'- numerous ecchymotic patches; bile in abundance was found in the small intestines; the bladder was filled with bloody urine; the blood in a fluid condition, and imperfectly drained from the larger vessels; 1018 Annual Report of New York the muscles of a dark mahogany color, and unlike that of any normal and healthy flesh. Specimens of the morbidly a%cted tissues and fluids were taken by Drs. Harris and Stiles for analysis and microscopical examination. Less than fifty of these cattle were slaughtered on this day (Sunday, the 9th August), and, by appointment, the medical offi- cers who were present agreed to meet on a subsequent day and continue their dissection. On Monday, August 10th, visited the slaughter houses located in Forty-fifth and Forty-seventh streets, near East river, found no sick cattle or diseased meat. Visited the Bergen cattle yards, in com- pany with Assistant Inspectors Howard, Wadsworth and Winslow, where we found several hundred cattle, but none of them exhibited any signs of the disease; thence Ave went to Communipaw, where the slaughtering of Mr. Alexander's infected herd was in progress. Mr. Lincoln, of the Board of Health, Gov. Marcus L. Ward and Dr. Harris were there by appointment for consultation. Several diseased cattle were inspected at slaughter; the tempera- ture ranged from one hundred and seven degrees Fahrenheit down to one hundred and two degrees.* Information was received that evening that a herd of infected cattle belonging to a Mr. Thomas, would arrive at the Bergen cattle yards. Early next morning (Aug. 11th), accompanied by the Sanitary Commissioner, Dr. Stephen Smith, and the Eegistrar of the Board, I visited the Bergen cattle yards just mentioned, and there saw some fifteen sick bullocks of the herd of sixty-six that had arrived at that place from Warren county, Indiana. A full history of this infected herd being embodied in the committee's general report, I need not repeat any portion of it here. • I owe it to the State commissioners to remark here that I have occasion to refer to the temperature records connected with my inspections of diseased cattle almost daily. With much satisfaction and a justifiable pride, as regards the advanced and very practical application of the exact science of medicine and hygiene, I beg leave here to state the fact that soon after the organization of the Metropolitan Board of Health in 1866, Dr. Harris, the Registrar, furnished its library with the latest and best treatises on those epizootics and other diseases of animals used for food, and requiring the attention of sanitary officers, and that his office which is a bureau of hygiene, as well as of vital statistics, has always been kept supplied with self-registering thermometers to aid in the diagnosis and study of disease when required. In all their inspections, the officers engaged in the study of the cattle disease have never failed to have with them, their self-registering thermometers, as trusty aids to ready diagnosis. To Dr. Harris, for his thorough knowledge of hygiene and the collateral sciences, and to his habits of organization and thoroughness in the inves- tigation of causes and results of disease, is mainly due the credit for the completeness of all this investigation and study of the Texas Cattle Disease. State Agricultural Society. 1019 Four of these Indiana cattle were carefully examined as to symptoms. The following points were noticed: Genei'al external appearance,' coats rough, heads hanging low down, eyes staring and dull, ears drooping, gait staggering, with tremor of flank muscles; foeces hard, small, covered with bloody mucous, urine dark and bloody; pulse one hundred and ten per minute, soft and feeble; respiration rapid, temperature at rectum one hundred and four to one hundred and nine degrees Fahrenheit. From one of these sick bullocks, bloody mucous was issuing from the nostrils. Three of the cattle were suffering from delirium, and though apparently frantic, were too feeble to do injury; they stood pressing their heads firmly against each other, or against the fence, their nostrils resting on or near the ground. The first figure seen on the right of plate No. 1, shows the appearance presented by the feeblest one of these delirious cases; the sketch was taken on the spot on the 13th August.* The muscles of the neck in one of these animals were exceedingly rigid on one side, and relaxed on the other, producing a kind of torticollis. The top of the head and base of the horns had an excessively high temperature. Professors Busteed, Liautard and others of the Veterinary College of New York, having arrived during this examination, and requested the privilege of selecting one of the sick animals for their own experiments, they were cheer- fully permitted to take their choice. Mr. McPherson, the superintendent of the yards, volunteered the information, that the residue of the infected herd were securely isolated in a pasture near by, where they would be kept until the authorities of New Jersey decided what should be done with them. AiK/ust 12th. In company with Dr. Harris and Sanitary Com- missioner Dr. Stephen Smith, visited the Bergen cattle yards. Eleven head of sick cattle from Thomas' herd were selected and placed in quarantine for observation. Three of these being very ill, temperature records were taken as follows: Fahrenheit scale. No. 1. Mooley. At 2 p. m lOlh degrees. No. 2. Brindle. do .- 105 do No. 3. Speckled. do 107 do *The signs by which the disease was characterized were deemed of sufBcient importance to warrant the sketching and exact illustration of them by a good artist. This forethought of the committee was certainly yery fortunate, for, notwithstanding the rory extensire prevalence of this disease in the West, and elsewhere, these sketches which the Metro- politan Board of Health has preserved, are believed to be the only series in existence that is at all complete. 1020 Annual Report of New York Three others were in small yards, belonging to the same herd, one of which had a temperature of one hundred and ten degrees. The fifty head, balance of the drove, were said to be placed in quarantine pasture near by, but were in fact, surreptitiously removed, no positive trace of them having yet been discovered. On August 13th, I received instruction from the Board of Health, through the chairman of their committee on cattle disease, to cooperate with that committee, and to give my time to the special duty of studying the symptomatology and clinical history of this affection as it appears in the herd yards. These instructions directed me to devote all my time to this duty, to make accurate notes of my observations, and to follow the directions of Dr. Harris, in my work under the committee.* On the same day visited Bergen cattle yards in company with Dr. Stephen Smith, Sanitary Commissioner, and Drs. Harris and Stiles, all of the Metropolitan Board of Health, and Prof. Liautard, of the Veterinary College of New York, Gov. Ward, of New Jersey, and Mr. Koehler, the artist. On arriving at the yards, discovered that but four remained of the eleven placed therein the day pre- vious. The other seven had either died or been slaughtered, and removed, it was said, to the rendering tanks. Those remaining, being in a dying condition, were immediately slaughtered and post mortem examinations held. Dr. Harris, who directed the scientific investigations, had the following observations made: No. 1. Mooley. Weight estimated 1,500 pounds gross. Blood flowing from the carotids; temperature, lOSj" Fahrenheit. . Fat, very yellow, jaundiced. Muscles, dark mahogony color. Liver very large, fatty; weight, 231 pounds,. softened. Spleen very large, engorged with dark blood ; weight, 9 pounds 2 ounces. Kidneys, dark color, congested ; weight, 4 pounds 6 ounces. Heart, muscular tissue softened; weight, 51 pounds. Gall bladder, distended, filled with dark, thick, flakey bile ; weight, 3 pounds 10 ounces; bile, sp. g. 1.030; temperature, 86° F. Urine, dark, bloody, about 1 qt.; sp. g. 1.035. . • This promptitude of action by the Board of Health in meeting whaterer exigencies arise has proved the surest means of preventing popular anxiety as well as protecting the public health. It has justly been remarked by one of the officers of the Board that "experience in the Metropolitan district has abundantly proved that the best way to pre- vent both pestilence and panic, is to know and prepare for the danger." (Notes on Cholera Prevention; addressed to Jackson S. Shultz, President Metropolitan Board of Health. By Dr. E. Harris.) State Agricultural Society. 1021 Colon, inner mucous coat, highly congested, with blood along the longitudinal rugae. Small intestines the same as colon. Rectum, intensely congested, rugae. Bladder, inner coat covered with bright red puncta. Lungs healthy; right weighed 7 pounds; left, 4 pounds. No. 2. JBrindle* In a dying condition ; slaughtered. , Temperature of rectum, 106° ; mouth, 1061° F. Nostrils hot, moist ; tongue pointed and retracted. Blood of aorta at slaughter, 106°; sp. g. 1.039. Fat very yellow, or greenish yellow color. Muscles, dark red, mahogany color. Liver enlarged, softened, fatty; weight, 273 pounds. Spleen engorged, softened to a pulpy mass; weight, 9| pounds. Kidneys very dark ; weight, 4^ pounds . Heart, muscular tissue softened ; 6 pounds. Gall bladder, distended, with thick, dark, flakey bile. Bladder, distended, with about two quarts of a dark, bloody urine; sp. g. 1020 j inner coat of bladder covered with bright red puncta. Small intestines injected with bloody puncta. Kectum, highly congested in longitudinal strige along the rugae. Coecum, inner surface covered with large ecchymotic spots. Omasum, its leaves inflamed; dry, and contents hard. Abomasum, highly inflamed, ulcerated in its pyloric extremity. Posterior nares, slightly injected with bloody extravasation. Brain, slightly congested. Lungs, healthy; right,-5l pounds; left, 4| pounds. No. 3. Speckled. Gross weight, 1,150 pounds; temperature of rectum, 107° F.; in a dying condition ; slaughtered. Blood of aorta, temperature 1074° Fahrenheit. Liver, enlarged, engorged with blood, and softened. Gall bladder, distended, with thick, dark bile. Rectum, coecum and small intestines highly injected with blood, forming striaa and ecchymoses along the margins of the rugae. Abomasum, highly congested, inflamed, and the pyloric extremity presenting large dark ulcers. Kidneys, dark color, congested. Bladder, filled with dark, bloody lu-ine. Aitgust 14:th. Visited Communipaw. The five cattle that were reserved for observation and treatment, through the kindness of Mr. Fitch and the superintendent, Mr. Payson, were this day placed in a lot where they had access to salt meadow-grass, and were com- * The appearance presented by the carcass of this animal is shown in plate 2, which was sketched by the artist as soon as the viscera were removed after killing the buUoclc See plate 2. 102'^ Amnual Report of New York pelled to driDk of the following mixture, which Dr. Harris had prescribed as an experimental remedy: Carbolic acid, 12 ounces in crystals; glycerine, 4 ounces; bicarbs. soda, 12 ounces. Mix. Directions — Dissolve or mix one ounce in 3 or 4 gallons of water. This was readily drunk by the steers. The surface of the ground was liberally sprinkled with heavy oil of coal tar, mixed with sawdust. Aitffust 15th. At Communipaw. The five cattle under treat- ment appeared evidently improving; they drank about two gallons of the medicated water during the past twenty-four hours. An ox, which had been in the same yard with the infected herd, was found dead in another yard. He was examined by the State inspector, Mr. Henry Taylor, of New Jersey, and presented the same lesions as had been observed in the cattle dying of the cattle disease in Mr. Alexander's herd, viz: "dark yellow-brownish fat, muscles very dark red, bloody dark urine, enlarged liver, gall blad- der filled with thick dark bile." August \Qth. This day, at Communipaw, one of the five under treatment was slaughtered for scientific investigation. The balance (4) appeared to be convalescent: Temperature 102°. Post mortem : urine clear, normal; sp. g. 1.020, acid- Spleen somewhat enlarged and engorged. Liver 11 lbs., somewhat softened, fat very yellow. Kidneys slightly engorged, paler than normal. Abomasum, mucous coat slight spots of congestion. Rectum, congested along the rugae. August nth. Visited National drove yards. One Hundredth street and Third avenue. Found an ox lying sick, unable to rise. Temperature 106°, breathing very rapidly, panting, pulse too soft and rapid to count. No owner or claimant. Sent him to render- ing dock. A post mortem examination was made. Post mortem chano;es had so obliterated evidences of disease as to make the examination useless, except that there was abundant evidence wit- nessed to show that this animal had died of a putrid blood poison: Liver, enlarged, softened; weight 16 2 lbs. Gall very thick, dark. Bladder, 1 quart of urine, dark, bloodj Kidneys, perfectly disorganized. Rectum gangrenous. Spleen, an enlarged, engorged, pulpy mass. State Agricultural Society. 1023 Abomasum gangrenous. Fat greenish-yellow. Muscles darkened mahogany color. Found an abaiidoued cow on First avenue, between Second and Third streets, in a dying condition. On examination at the render- ing dock, disclosed pleuro-pneumonia. August 19th. Examined 720 head which arrived this morning at Bull's Head, in which lot were Mr. Pile's drove of 85 head, two of which were afterwards taken sick. Eeceived this day the following telegram from Albany: \_Copy.'] Albany, Augml 18, 1868. To Hon. Geo. B. Lincoln, President Metropolitan Board of Health: Sir — Be pleased to send to Millerton on the Harlem railroad, Dr. M. Morris, to act as assistant commissioner under and pursuant to appointment, under chapter 740, Laws 1866. There are diseased cattle at Millerton, and Dr. Morris is empowered and directed to carry out the suggestions of the Sanitary Committee of the Metropolitan Board of Health, as published in Saturday New York papers in relation thereto. (Signed) M. R. PATRICK, Chairman of State Commissioners. August 19th. I immediately, upon the receipt of the foregoing order, proceeded to Millerton, Dutchess county, N. Y., arriving at about 6 o'clock p. m. on the same day. On the morning of the 20th inst., having learned that a part of the sick herd had been sent to New York the day previous, number- ing seventeen head, sent telegram to head-quarters to have them seized, but it proved too late, as they had been disposed of and could not be traced. At Millerton, found a portion of a drove of cattle belonging to A. W. and Nathaniel Smith, of 73 Washington avenue, Albany, N. Y. This drove originally numbered sixty-five head, and left Albany on the 9th August, traveling overland towards New York city. They appeared to be a mixed lot of cattle — Illinois, Indiana and others. On the 12th of August, twenty head of this drove were left at Copake, Columbia county; one of these died on the 17th August, after an illness apparently of about forty-eight hours. The symptoms, as described by eye witnesses, were the same as those I had observed at Bergen cattle yards and Communipaw, viz: head low down, ears drooping, arched back, great debility, stagger- mg gait; would not feed, finally lying down, unable to rise until death supervened. He was deeply buried. On the 13th August, 1024 Annual Report of New York forty-five head of this drove arrived at Millerton, Dutchess county, N. Y., twelve miles from Copake. Of these on the 14th, two died; 17th, one, and 19th, one. Making the record of this drove thus far as follows: Five deaths — 14th, two died at Millerton; 17th, two died, one at Millerton and one at Copake; 19th, one died at Millerton. On the morning of 19th August, the owner fearing still greater loss, shipped seventeen head of the infected herd for New York by the New York and Harlem railroad, leaving twenty-four head at Millerton, and nineteen head at Copake. Two of those at Millerton are looking ill, the remainder appear to be well, but all being a suspected herd, were quarantined to be retained until all danger had passed. The dead animals had been buried in a lot adjoining the pasture where the cattle were found. These two lots of land were therefore set apart as quarantine ground, and the following order issued to Mr. William H. Barton, of Millerton, who was placed in charge: Millerton-, Dutchess Co., N. Y., j^ugust 20, 1868. TbMn. W. H. Barton: Sir — You will please retain under your personal supervision, the twenty-four head of cattle belonging to A. W. and Nathaniel Smith, of Albany, in the two lots adjoining and belonging to the estate of Mr. John Campbell, where the cattle now are and have been pasturing. You will retain them for one month from this date, or until further order from the State commissioners or their assistants. You will not allow any cattle to come within one thousand feet of the quarantine ground. Provide them with plenty of salt and feed if necessary. If any are taken sick, confine them in a separate enclosure from those that are well. All animals of this herd that may die, are to be buried at least four feet under the ,» surface of the ground, covered with lime or carbolic acid for disinfection. The lots where the cattle are, or have been, to be disinfected with carbolic acid. By order of the State Cattle Commissioners. (Signed) MOREAU MORRIS, Assistant Commissioner. Proceeding to Copake, Dutchess county, the same day, the balance of the drove were found, numbering nineteen head, upon the farm of Mr. E Van Benschoten. None of these presented any evidences of the cattle disease, but as they were a part of the infected herd, they were placed in quarantine. The same order (in substance) was issued to Mr. E. Van Benschoten as to Mr. Barton, at Millerton. August '2,1st. Learning that there were sick cattle at Ameiiia, Dutchess county, I proceeded thither, and found upon the dairy farm 5/ State Agricultural Society. 1025 of Mr. Abiah P. Baylis, that out of a herd of thirty, nine had died during the four previous weeks. This herd consisted of twenty- seven cows, one bull and one pair of oxen; of these, seven cows, the bull and one ox had died. Three cows and the remaining ox were found sick with pleuro-pneunionia, and the symptoms, as described by Mr. Baylis and the attendants, led me to conclude that those that had died, were all victims of the same disease. During the illness of these cows, their milk had been regularly sent to New York city for consumption. Orders were imme- diately given, under the authority of the Board of Health, as its inspector, that no more milk from the infected herd should be sent to New York city. The remainder of the herd were placed in quarantine, upon Mr. Baylis' farm, under the supervision of Dc. Desault Guernsey, of Amenia, for observation and report, and a copy of the same quarantine order left with him ixs, was given to Mr. Barton. Five more of this dairy herd were subsequently taken sick, making nine head which were put under treatment; all these finally recovered.* August 21st. Returning to New York city, I immediately insti- tuted a thorough inspection of all cattle in the yards of the National drove yard, at One Hundredth street and Third Avenue, and con- tinued such inspection daily as they arrived from any source. August 24:th. Two sick cattle were found at Bull's Head, in a drove belonging to Mr. S. D. Pile. These left Arrow Rock, Selene county, Missouri, on the 3d day of August, 1868, numbering 83 head, and crossed the Mississippi river at St. Louis ; here the two sick ones were said to have been added to the drove, making 85 head in all. From St. Louis they were shipped by railroad to Buffalo, Albany and New York city, and arrived at Bull's Head on the 19th instant. On the 22d, these two were observed to be ailing, refusing food, and continued getting worse; but all knowledge of their illness was carefully kept from me until the 24th inst., when they were seized and placed in quarantine hospital, under obser- * The treatment of these cases showed a remarkable result, viz : out of a herd of thirtj head, eighteen were diseased; nine of these died before any treatment was instituted; the other nine all recovered under treatment. The medical and hygienic treatment was as follows : The sick animals were placed in a small enclosure by themselves. Pure carbolic acid was placed in a large open-mouthed bottle, dissolved in water. This was held to the nostriis, and given by inhalation at short and repeated intervals. The heavy oil of coal tar, containing 70 p. c. of carbolic-acid, was liberally sprinkled upon the j'ard where they were kept, thus presenting the fumes of the carbolic acid constantly. The feeding was low diet, plenty of water, salt, and out-door air. [Ag.] 65 1026 Annual Report of New York vation. Fifty head of this drove had been sold for slaughter, and I have no doubt, from subsequent information, that diseased ones were among them. Thirty-three head now remained. Of these, there were 17 head of Cherokee cattle, which did not exhibit any evidence of disease; they were allowed to be sold for slaughter. The balance of the herd, 16 native cattle, were placed in quarantine pasture, near King's Bridge, on the 25th August, where they were retained for four weeks, when, no further evidence of disease appearing among them, they were released. August Ihth. This day a post mortem examination of one of the diseased steers from Mr. Pile's herd was held. Present, Drs. E. Harris, R. C. Stiles, and B. Howard, Assistant Inspector, — all of the Metropolitan Board of Health. A valuation of $30 having been fixed upon, he was slaughtered:* White steer, killed August 25th, 2 p. m., at One Hundredth street. Been obviously sick thirty-two hours: Temperature rectum, 1071'^ F. ; respiration, 36; pulse, 76; nostrils, profuse mucous discharge, streaked with blood ; anus appears dry and contracted ; faeces almost natural ; urine bloody ; animal balances himself by strongly twisting its head and neck to the left. Post Mortem Observations. — Temperature of blood, 107'' F., reaction neutral; temperature of liver, 17 minutes after death, 106°, and in the middle of this organ, ,19 minutes after death, 1071'*; appearance of subcutaneous surface, healthy; peri- toneal cavity, its fat intensely yellow, cavity contained a large amount of bloody looking serum ; gall bladder, distended; bile, sp. gravity, 1.025, reaction neutral ; urine, sp. gravity 1 009 1, neutral; liver, healthy in color and consistence; weight, 18 pounds ; kidneys, apparently healthy ; weight of one, 1 pound 6 ounces ; of other, 1 pound 7 ounces; spleen, 6 pounds 2s ounces, dashed with large chemoses upon anterior surface, the entire tissue being much engorged and easily broken down ; bladder, especially at the bas fond, covered with ecchymotic spots ; small intestines congested, presenting a general dark blush, no spots; lymphatic glands, in cellular tissue liver-colored, intensely yellow in center, with dark green towards surface. * Regarding the history of the two bullocks of Mr. Pile's drove, -vyhich brought his 16 other native cattle under the suspicion that took them into quarantine, it was ascertained that Mr. Pile had purchased them three weeks prior to my quarantine order concerning the herd. He had purchased these cattle at East St. Louis, for the purpose of filling a oar, as before mentioned, and they exhibited no sign of sickness until two days before I saw them. As they appeared to him ailing, he endeavored to dispose of them surrepti- tiously, but fortunately they were discovered during inspection, and at once placed under quarantine restrictions. The presence of these siek cattle had already depreciated the value and interfered with the sale of the whole herd. Facts which have since been communicated to the Board of Health, warrant the conclu- sion that these two sick bullocks of Mr. Pile's herd received their infection at or near the yards at East St. Louis, where he purchased them; hence, the period of incubation in them could not have been less than twenty days to the first appearance of obvious symptoms at the National drove yards. State Agricultural Society. 1027 The temperature record of the second steer, belonging to Piles' drove, is as follows: August 24th, 105i« F.; August 25th, 105°; August 26th, 104«'; August 27th, 104° ; August 28th, 103° (chewing cud) ; August 29th, 103^° (appeared dull, does not chew cud) ; August 30th, 103° (was bled this day one-half pint from the cer- vical vein); August 31st, 101° ; September 1st, 101°; September 3d, 100|°. August 2bth. This day made report to the president and sanitary committee of the Board of Health, and to the State commissioners, through Gov. Feuton, as follows: New York, Jugust 25th, 1868. To His Excellency Gov. R. E. Fbnton, and the State Commissioners on diseased cattle: Sirs — I have the honor to report that two cattle were found sick with the cattle plague at the National drove yards. New York city, on the 24th inst., belonging to a drove of eighty-five head, which left Arrow Rock, Selene county, Missouri, on the 3d of August inst., owned by Mr. S. D. Pile, of the aforesaid place. The two steers, now sick, were bought in St. Louis ("to fill a car") and came through with the drove by railroad by way of Buffalo and Albany. They arrived in the National drove yards 19th inst. Fifty head were sold immediately upon arrival,- leaving thirty-three head ; of these, seventeen head were Cherokees ; they were selected out and allowed to be sold. Sixteen head of native cattle were removed from the yard to quarantine pasture, which I selected, near King's bridge, on the "Dyckman estate." The yards have been thoroughly disinfected. August 25th. To-day held a post mortem examination upon one of the two sick from Mr. Piles' drove, at which were present Assistant Commissioner Orton, Drs. E. Harris, R. 0. Stiles, B. Howard, all of the Board of Health. The evi- dences of the disease were well marked. In order to prevent the surreptitious movement of suspected and diseased cattle from the National drove yards, I have this day quarantined the whole of the yards, and ordered that no cattle be allowed to leave them without a proper inspection and permit, signed by the Assistant Commissioner. The paramount necessity of protecting the public health, as far as possible, with the advice of the president of the Board of Health and its officers, have induced me to take this decided action with reference to this point. Hoping it may meet your approval, I remain, respectfully. Your ob't serv't, MOREAU MORRIS, Assistant Commissioner. The followmg quarantine order was issued this day upon Messrs. Allerton, Dutcher & Moore, of the National drove yards, New York city: New York, Angust 25th, 1868. Messrs. Dutcher, Moore & Co., National drove yards : Gentlemen — By virtue of the powers conferred upon me as Assistant Commis- sioner of the State of New York, in the act passed April 20th, 1866, chap. 740, and 1028 Annual Report of New York amended April 19th, 1867, with reference to infectious diseases of cattle, I hereby- designate the whole of your yards and enclosures, located between Ninety-seventh and One Hundredth streets, and Third and Fourth avenues. New York city, as quarantine grounds. You are hereby enjoined from allowing any cattle to leave said quarantine grounds, without special permit signed by the Assistant Commissioner. KespectfuIIy, MOREAU MORRIS, Assistant Commissioner for the State of New York. Aitffust 2Qth. Inspected this day, 1,486 head of cattle at Bull's Head, and made report to President Lincoln and Sanitary commit- tee of Metropolitan Board of Health, as follows: New York, August 26th, 1868 Geo. B. Lincoln, Esq., President Metropolitan Board of Health, and Committee on diseased cattle : For your information, with reference to the progress, control and investigation of diseased cattle, I have the honor to present the following statement : Learning the fact that a large number of cattle were expected to arrive at the National drove yards, by way of the Hudson River railroad, at two o'clock this morning, and fearing that some might escape the proper inspection before being slaughtered, a request was made of your president for a suflBcient force from the Sletropolitan police to aid me in securing the inspection. This aid was kindly afforded by that department, and proved of great value, as no cattle arriving either at Hudson River railroad depot, or by Harlem River railroad, or any other inlet, have left the drove yards without a careful inspection. Measures had been taken previous to their arrival, under the authority conferred upon the Assistant State Commissioner, so that no cattle could leave the yards without such inspection and permit. Under this arrangement, I am happy to be able to say, that I believe no diseased cattle have escaped observation. All that arrived at the drove yards underwent a personal inspection, and were found apparently in a sound, healthy condition. These numbered 1,101, and, with 393 which were yet in the yards from last market day, made a total of 1,494 head of cattle inspected this day. These cattle are from Missouri, Illinois, Indiana, Ohio, Kentucky, and this State ; some of them from the Cherokee country. One, which I have reasons for believing had been turned out of a slaughter-house near by, was found on the Third avenue, near One Hundred and Sixth street, very sick. He was placed in the hospital lot attached to quarantine, where he will be retained for observation. The effect of this decided action, in the thorough inspection of all cattle arriving at this large depot for distribution, will be, that more care in the selection of droves, and the exclusion of any suspected of having disease, will be exercised at distant points. It will be very difficult to forward diseased cattle to this market by any of the usual routes from this time forth, as I learn by recent advices that at all the prominent stopping and feeding places competent commissioners and inspectors are constantly on duty. Nevertheless, New York city presents so many exposed points at which cattle may enter and pass to the numerous slaughter houses scattered throughout the Metropolitan district, where unscrupulous persons are ever ready to seize oppor- State Agricultural Society. 1029 tunities, and where it is almost impossible to maintain a thorough system of inspection either of cattle or meats, that I would respectfully and earnestly beg to offer the following suggestion : In order to be able thoroughly and efficiently to certify that no diseased meat either be slaughtered or offered for sale, the business of slaughtering must be confined to fewer points, and at such places as afford the largest facilities for thorough observation ; that no meat be allowed to be sold without proper certificate of inspection. In pursuing investigations with reference to this important subject, as respects the health of the people of this city and Brooklyn, most startling facts appear, and to my own mind afford a reasonable conclusion as to the variations in the death-rates, as furnished by your registrar from time to time. Not only diseased beef, but other meats, as well as vegetables and fruits, must share the responsibility. In order to secure the inhabitants of the ^letropolitan district from the danger of purchasing diseased meats, it is absolutely necessary not only that animals should he inspected upon the hoof, but that a more careful and thorough examination of internal organs, while being dressed for market, should take place* It is a well known fact that a large proportion of the meat slaughtered and inspected under Levitical law for the the use of our Israelitish population, is condemned as respects its use by them, but sold at equally high prices for use by Gentiles. Up to the present moment no new cases have been discovered. Respectfully submitted, MOREAU MORRIS, Sanitary Inspector M. B. H. To-day a red ox was found abandoned on Third avenue, near One Hundred and Third street, evidently dropped out of some drove going to Bull's Head, from the landing place on Hudson River railroad, at One Hundred and Twenty-fifth street. He was placed in quarantine hospital. Temperature 106° F. Very feeble; feverish, with staggering gait; all the white of the eyeballs deeply jaundiced; tongue dry, nostrils dry, horns hot; is uneasy; lies down often. August 21tJi. Temperature 105° F. The animal evidently sink- ing; unable to stand, dying, and at 8:30 he was dead; sent to rendering dock; examined within six hours, and found to present the well defined lesions belono-ing- to the Texas cattle disease. Another ox was taken to the rendering dock this day in a sur- reptitious manner, with the hope of not being discovered. This ox came from a slaughter house in Stanton street. An examination revealed the same cause of death as in the former case. This animal was purchased at Bull's Head on the 20th inst., during my * Such inspection is now pursued at the Communipaw abattoir, under the authority of the State of New Jersey, by a competent and careful inspector, and it will at once tran- quilize the public fear of diseased meat from that point, and secure a healthy supply. 1030 Annual Report of New York absence from the city, and had been kept in a dark shed near the slausjhter house in Stanton street durino^ the interval. To return to the daily record of duties, I need to present in this place the results of post mortem examinations which were made upon the four remaining bullocks of Mr. J. T. Alexander's herd, which had become convalescent at Communipaw. One of the five sick bullocks which had generously been set aside by Mr. Fitch (the agent of Mr. Alexander), for the uses of the Metropolitan Board of Health in studying the disease, was slaughtered on the 17th, and results were observed which have been described in the general report by Dr. Harris. It remains to present in this place the post mortem inspection of the remaining four. They had been about fifteen days apparently convalescent, and had been three or four days very sick, with all the symptoms of the disease. Efforts were made to obtain temperature observations daily, but such observations were made with great difficulty, owing to their restless and wild state; yet on the 9th, 10th and 11th, the tempe- rature was taken once or more daily in the rectum of each one, and was found to average about 105° F.; but in no one did it reach 107° F. The post mortem dissections of these four bullocks com- menced at 2 p. M. These four bullocks were seen to exhibit the usual symptoms of the Texas disease at the first and second visits which the medical officers made to the yards at Communipaw, viz: on the 8th and 9th of August. The lopped-horn steer, which was slaughtered on the 16th, was, at the former dates, believed to be rapidly approach- ing a fatal result, but these four others were only then beginning to exhibit symptoms. They had been carefully fed, and in their drink each of the bullocks had taken a little more than half a drachm of carbolic acid (Calvert's best chrystalized) in two thou- sand pai-ts of water, as before mentioned. Record of Post Mortem Examinations. Steer No. 1. Temperature of blood, 103® ; thirty-two ounces coagulated firmly in twelve minutes. Temperature of liver, 102" in center of right lobe, fifteen minutes after death. Urine, specific gravity 1.009, clear, slightly alkaline; no albumen. Faeces thin, but natural. Lungs healthy. Liver healthy; weight 12| pounds. Gall bladder healthy. Abomasum, over a large space, signs of recent great congestion. All this part had a whitish appearance, as if the congested membrane had been recently acted State Agricultural Society. 1031 apon by carbolic acid. There were two or three superficial ulcers scattered about, having the same appearance, as if almost healed. This whitish appearance was not attributed by the gentlemen present to the action of the carbolic acid which the animal had swallowed while under treatment ; it was considered, rather, to consist of epithelium scales cast off during the progress of the reparajtive process which seemed to be rapidly advancing. Steer No. 2. Temperature of blood, 1031'' F. Temperature of liver, 15 minutes after death, lOl^". Urine, specific gravity, 1.022; alkaline; contained a good deal of albumen. Kidneys remarkably healthy. Heart healthy. Liver weighed 15 5 pounds. Abomasum suffused with a moderate blush, and sprinkled with miliary white patches. Mucous membrane darkly eroded in small patches, but evidently healings iu pyloric extremity . Rectum shows signs of recent congestion, but seems now very nearly natural. Steer No. 3. (A tall, lean animal.) Temperature of the blood at death, 103 5". Temperature of middle of liver, 15 minutes after death, 103 75-100°. Urine, specific gravity 1.025 ; neutral, inclined to alkaline. Kidneys healthy. Liver weighed 13 pounds. Spleen weighed 4 pounds, being engorged and enlarged. Stomach and contents in good condition. Rectum gives evidence of recent congestion of great extent, which now is quite limited. Steer No. 4. Temperature of blood 103 i° ; coagulated in 15 minutes. Temperature of right lobe of liver, 15 minutes after death, 1035°. Urine, specific gravity 1005; neutral, or slightly alkaUne; no albumen. Liver weighed 11 5 pounds. Spleen weighed 31 pounds ; much engorged and slightly softened. . Abomasum shows evidence of recent disease ; the papUae much enlarged at val- vular portion. About three inches from pylorus are seen recent and deep erosions cicatrizing. August 28th, 29th and 30th. Inspected cattle at Bull's Head, as usual. None found sick. Early in the morning of the 30th, Dr. Harris, and Prof. Cope- man, a veterinary surgeon, joined me at the National drove yards, for. the purpose of taking specimens of blood from the cervical veins of the remaining sick ox of Mr. Pile's herd. The temperar ture that morning was 103° Fahr. Four vials, containing two ounces each, were taken. Tjie result of the analyses, as given by Prof Chandler, can be seen in the general report. This animal seemed to improve temporarily after the loss of this small amount 1032 Annual Report of New York of blood, for his temperature on the subsequent mornmg was found to be 2^° lower. Aiigusl ^Ist. The following notice was issued in the morning papers of New York city: To Drovers and Butchers. Under the authority conferred by the laws of the State of New York, enacted April 20th, 1868, chapter 740, section 9, I hereby order and direct, that all beef cattle and cows landing or arriving within the limits of the city of New Yorl^, be yarded at the quarantine yards. One Hundredth street and Third avenue. Eleventh avenue between Fortieth and Forty-first streets, city of New York, there to be properly inspected. All cattle found traversing the streets of this city, without a permit signed by the Assistant Commissioner, will be seized and taken to the quarantine yards for inspection, unless so far diseased as to require other disposi- tion. This order to take effect on and after Wednesday the 3d day of September, 1868. (Signed) MOREAU MORRIS, Assistant Commissioner. The following supplemental order was issued on the 3d Sep- tember, 1868: Notice to Owners op Milch Cows. A temporary quarantine yard is hereby established for milch cows at Chamber- lin's yards, Nos. 70, 72 Robinson street, where they will be inspected daily, and permits given. Blank permits were provided, of which the following is a copy: No New York, 186 . I hereby certify that I have inspected head of cattle belonging to and allow them to leave quarantine yard. jtssistant Commissioner. These were furnished whenever cattle left the quarantine enclo- sures, and proved to have been of the utmost value as time progressed. Finding that cattle were surreptitiously taken to slaughter houses without the proper inspection upon the hoof, on the 31st August, 1868, the following communication was addressed to the President of the Metropolitan Board of Police through the Presi- dent of the Metropolitan Board of Health: Hon. Thomas C. Acton, President Metropolitan Board of Police: f Sir — Deeming it essential to secure the support and cooperation of your police force in order to enforce the provisions of the order herewith enclosed (notice to drovers and butchers), which I find necessary to issue to secure a proper inspec- tion of all cattle entering this city, that the spread of infectious disease among cattle, and the sale of diseased meat for food, may, as far as possible, be prevented, State Agricultural Society. 1033 I would respectfully solicit of your honorable board that an order be issued to its officers, that all cattle found traversing the streets of New York city, without a permit, signed by the assistant commissioner, be seized and brought to the quaran- tine yards for proper inspection. Having found by actual experience during the past week that it is impossible to secure a proper inspection of cattle, arriving at the market, under present circum- stances, and from the well ascertained fact that many diseased animals are taken to slaughter houses without proper inspection, I am compelled, by the great responsibility which is imposed upon me under the law of the State Commission, and by the requirements of the Board of Health, as its oflBcer, to take such mea- sures as will secure, as far as possible, a proper guarantee that no infectious disease shall spread among cattle, and that diseased animals shall not be slaugh- tered for food in this city. Your cooperation to this end is therefore earnestly and respectfully solicited. An early reply is desired, that prompt and decisive measures may be taken. Very respectfully. Your obedient servant, MOREAU MORRIS, Assistant Commissioner for New York State. The Metropolitan Board of Health, on the 2d September, 1868, at a regular meeting, adopted the following: Whereas, Assistant Commissioner Dr. Moreau Morris has found it necessary to establish two quarantine yards in the city of New York, for the purpose of securing the needed sanitary inspection of all cattle arriving within the city limits : Resolved, That the Metropolitan Board of Health hereby expresses its unani- mous approbation of this official action of Assistant Commissioner Morris, and requests the Metropolitan Police Commissioners to enforce strict obedience to the orders and regulations which Dr. Morris has established concerning such quaran- tine inspection. September 1st. At Bull's Head inspected 511 head of cattle. In one drove of 27 head, belonging to Mr. Wm. Thompson, from Illinois, there was a sick ox; he was removed to hospital, and kept under observation for several days, until he recovered and was discharged. September ?>d. Commissioners Gen. M. R. Patrick and J. Stan- ton Gould, and Assistant Commissioner Dr. Manlius Smith, their secretary, met Dr. Harris and myself for conference, and on the 4th visited Communipaw (New Jersey), and the New York Rend- ering Company's dock, and terminated the day at National drove yards. One Hundredth street, where we slaughtered and dissected the remaining ox of Pile's herd. Present at the post mortem exami- nation: Drs. Harris, Stiles, Chandler, Howard, and Mr. Kohler the artist, besides the Commissioners and Assistant Commissioner before mentioned. 1034 Annual Report of New York This animal had. seemed to be but lightly attacked. The bloody' urine, staggering gait, and increased temperature being the main evidences of disease during life, while the chief evidence of dis- ease, as discovered at post mortem examination in this case, con- sisted in the deep discoloration of the muscles and the fat; the presence of extensive erosion and sloughing in the pyloric portion of the fourth stomach, and in the usual conditions which have attended this disease in the lesions of the liver and spleen; and most of all, in the microscopical evidence which had been obtained on the 30th of August, from blood drawn from the cervical vein and examined by Dr. Stiles; also, the blood taken at the time of slaughter. Sejptembet' Wi. There arrived at Bull's Head, a car-load of 19 head of cattle, from Illinois, bought by Baker, at Albany, and shipped to care of Bright & Fagan. The whole lot not appeai"ing well, were placed in quarantine hospital. The temperatures of all were taken. At 3:30 found an ox from this car-load unable to rise, presenting the prominent symptoms of the cattle fever: head drooping near the ground; eyes staring, dull; horns cold, body hot, breathing rapid; pulse very feeble, unable to count it; coat rough, flies adhe- rent, temperature of rectum 106^° F. Killed at 6:30 p. m. same day at rendering dock. Temperature, 105 1°. Temperature of blood at slaughter, 103°. Temperature of liver, 15 minutes after death, 106°. Bladder contained 30 ounces of " black water ;" much distended ; mucous sur- face of neck of bladder odematous ; inflamed. Rectum contained small quantity of hard, rolled dung; the mucous membrane engorged with black blood; rugae striated with blood. Abomasum, whole inner surface a dark purplish color ; pyloric extremity deeply eroded over about one-twentieth part of the surface ; the erosions also found on the larger folds ; the upper part of the intestine in a like condition. Kidneys enlarged ; color very dark ; engorged with dark blood throughout. Gall bladder distended, with thick, dark, ropy bile. Liver weighed 23 1 pounds, without fat or gallbladder; fatty, engorged with blood. Heart large, flabby ; blood extravasated between muscular and mucous surfaces Fat a dark greenish-yellow color, without consistence. Muscular tissue very dark mahogany color ; soft and flabby. On this date (September 9th), temperature observations were commenced upon this herd of Bright & Fagan's. (Mr. Baker, of Albany, is said to be the owner and shipper.) State Agricultural Society. 1035 TEMPERATURE RECORD of nineteen head of Cattle shipped to care Bright Sf Fagan, 5ih September, 1868, by Baker, of Albany, from Buffalo. Arrived at Bull's Head, N. Y., September 9th. No. Sept. 10. Sept. 11. Sept. 12. Sept. 14. Remarks. 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 102 » 1021 1021 lou 102 1021 102^ 102i 103 103 lOli 102^ 1021 102^ 104 102^ 1021 102 e 102 101 1021 1021 102 103 102^ 104 1031 102^ 102 102 I02h 1021 102 102 101 " 102 101 101 101 100 102 102i 101 101 101 ion 101 101 lOU 101^ lOU 104 1011" 1011 101 101 101 101 lOU lOU 101^ 101 101 lOU 101 1001 101 101 101 lOU This lot of 19 head, losing one, were discharged from hospital on the 18th Sep- tember, well. lOlh slaughter. September 11th. Mr. Dayton, the inspector, and myself, found at One Hundredth street, a bullock of the Bright & Fagan herd, with symptoms of the disease, bloody urine, &c. He was slaughtered at 4 p. M. Record of Post Mortem. — Temperature of rectum before slaughter, 107° F. (Temperature at 9 A. M., 1071".) Temperature of blood flowing from aorta, 107*^ ; temperature of liver, nine minutes after death, immediately upon opening the abdo- minal cavity, and plunging the thermometer in the center of the liver, 108" ; weight of liver, 18 1 pounds ; color of this organ, a mottled and ochrey coffee au lait color. Specific gravity of blood, 1.021 ; gall bladder excessively distended, and containing S pounds, 10 ounces of thick flaky bile; specific gravity of this fluid, 1.018. The spleen weighed 5 pounds, 2 ounces, and was ecchymotic in appearance, and almost diffluent in its substance. The kidneys weighed 1 pound, 8 ounces each. Septembe)' 12th. Early in the morning, police officers of the First precinct, telegraphed to Dr. Harris' residence, and to the office of the Board of Health, that twelve cattle had died during the night at Pier 12, East river. Taking Capt. Lord, of the Sanitary squad, Dr. Harris proceeded to that pier, and to the steamer "Fah Kee," which lay on the north side of that pier, and on its outer end, and they there ascertained that fourteen bullocks had died on board or upon the dock, aft&r being taken off the ship, during the night and morning. There were twenty-six remaining alive; these were being disembarked. It 1036 Annual Report of New York was immediately ascertained that this herd of forty fat bullocks had been purchased and driven down from One Hundredth street during the previous day (September 11th), and that they had been care- fully put on board the " Fah Kee" before dark; that the portion of the ship in which they were placed was the main deck, forward of the engine; that they had been purchased by a Mr. Harvey, the contractor who supplies the Bermuda market, for use of the troops, «fec., but that they had undoubtedly come from one or two droves recently arrived from some point west of Toledo via Buffalo. The twenty-six surviving bullocks were ordered to be carefully driven to the Battery to remain until sunset, as the day was exces- sively hot. I inspected these cattle at the Battery, and ordered them to be removed to Bull's Head during the cool hours of Saturday night and Sunday morning, and took steps immediately to discover what- ever could be ascertained concerning the origin of the herd. Found that they came from Illinois in a drove of one hundred and eight head, brought by "Farlow," and the whole lot were bought by Joseph Williams and William Thompson, in Albany. Before night of the 12th, fourteen head were dead, and during the following two days, three more died, making seventeen in all, dead out of the lot of forty head. The remaining twenty-three head were placed in hospital at Bull's Head until the 17th, when they were removed to quarantine pasture near King's Bridge, where they remained until 8th October (three weeks), when they were released, being entirely convalescent, and appearing to b» well. On the 12th October following, they were sent to Bermuda, and arrived in good condition. Post mortem examination revealed the cause of death unmis- takably as being of the Texas cattle disease. The following is a concise abstract of notes made in ten of the post mortem examinations which were held September 12th, 13th and 14th, upon the "Fah Kee" cattle: No. 1. Dissected at 5 p.m., six hours after death. Died at 11 a.m., soon after being taken out of the vessel. The temperature at IO5 a.m., as examined in the presence of Dr. Harris, half an hour before death, at pier 14, was 110° Fahr. On post mortem examination, the spleen was found normal in appearance; weight, 1 pound 7 ounces. Urine, specific gravity 1.019. Weight of hver, with gall bladder, 141 pounds. No. 2. Weight of liver, without gall, 14 lbs. The spleen and kidneys were dis- organized. State Agricultural Society. 1037 No. 3. The paunch and diverticulum moderately filled with undigested materials. The omasum and abomasura nearly empty. The maniplies of omasum have per- fect papulae, but their blood-vessels are deeplj^ injected throughout with extrava- sation of disorganized blood-vessels beneath the mucous membrane in several of these maniplies. The abomasum shows throughout the whole pyloric portion cicatrized ulcerations, but the membranes are so much altered since death that the full extent of these changes are not easily described. No. 4. Exhibits more extensive erosions and recent cicatrices than No. 3. The abomasum was distended with black blood and some of the ordinary contents. No. 5. Resembles No. 4 in every particular. Recent cicatrices covering the tubular portion of the abomasum from the pylorus back to the folds. The kidneys of the whole three were in a state of diffluent decomposition . Two patches of the folding or omasal portion of the abomasum appear to have been gangrenous before death; deep ecchymosed if not gangrenous. No. C. Was like No. 3, in every respect. No. 7. Is the red bullock seen alive by Dr. Harris at the vessel, and whose tem- perature at rectum was 108° in the moribund state, at 101 A. m., yesterday. Post mortem at 11 A. M., 25 hours after death. Stomachs in a fair state of pre- servation. The abomasum contained a small amount of ordinary material, and about a pint of thick, tarry blood. There were recent and partial cicatrizations and extensive erosions throughout the tubular portions of this stomach. The liver and kidneys were of a chocolate color, containing a little blood. No. 8. Is the bullock Dr. Harris saw rescued from the water [into which it fell while being lifted off from the deck of the " Fah Kee "]. This bullock was slaugh- tered at the rendering dock, when in the moribund state. The temperature (immediately upon opening the abdomen), in the fat of the kidney, was lOS'', and in liver, lOSj''; the stomachs were moderately filled. The omasum showed no extravasated blood, but the epithelium peeled oif readily at every point. The abomasum contained but a small amount of its ordinary material, and this was mixed with extravasated blood, or the coloring matter of the blood. The fimbri- ated or folding portion presented upon several of its margins and folds long patches, erosions, and sloughs, and throughout the entire circumference of the upper por- tion of the pyloric, or tubular section, old erosions partially healed or recently cicatrized, studded the surface. Specimens were saved. September \4ih. Slaughter and dissection of two that survived to this date. No. 9. Steer from vessel (that had fallen out of drove at 14th st. at 11 p. m., Sept. 12th), killed at 4:45 p. m. Temperature of rectum just before slaughter IQOhp. Temperature of blood at slaughter, 101|°. Temperature of liver, 15 minutes after death, 101 5*^. The rectum, commencing two inches from the anus, on its inter- nal aspect, presents two deep ulcers; one extending five inches in the direction of the longitudinal rugae ; another extending about an inch. Weight of liver, 223 pounds. Spleen eiigorged and enlarged, weighing 3 pounds. No. 10. The steer from Robinson street (fell out of the drove when being driven up from the Battery, and was allowed to remain until this hour for slaughter). Liver, 223 pounds. The abomasum contained patches of the characteristic ero- sions, some recent, and some nearly healed. The tubular rugae of rectum engorged throughout their whole extent. 1038 Annual Report of New York 8e]ptemher 15th. During the inspection at Bull's Head this day, a sick steer was discovered in the drove belonging to Mr. P. F. Carey. Temperature of rectum, one hundred and seven degrees Fahrenheit. A valuation of eighty dollars, contingent upon condi- tions to be discovered, having been made, he was ordered to be slaughtered. The temperature record of this steer this day, was as follows: i 8 o'clock A. M., 104* Fahr., at 1 p. m., lOS*^, and at 1:30 o'clock p. m., he was slaughtered in presence of several inspectors of the Board of Health, who had been detailed this day to make investigations in the slaughter houses, with reference to diseased animals and meats. Temperature of blood flowing from carotids, 106 1° F. ; of liver, fifteen minutes after death, 1055° F. Post Mortem Appearances : Omental fat, brownish yellow ; other fat, lightet yellow; muscular tissue, dark red. Liver weighed 16 j pounds, and presented excessive fatty degeneration, engorged with blood, softened. Gall bladder distended, with thick, dark flaky bile. Urine normal. Abomasum : upon mucous surfaces, dark, irregular shaped, elongated erosions, some in process of cicatrization, and upon the pyloric portion, several large cicatrices were se«n, where the eroded surface had healed ; spleen enlarged ; weight 21 pounds, congested. Kidneys engorged with blood, color dark; weight of both, 5 pounds. Rectum presented a few points of inflamed rugas. Omasum, papilae contracted; surfaces dry, filled with hard cakes of food. September 11th, ISf.h, 19th, 20lh. Inspected cattle at Bull's Head, and also made examinations at slaughter houses with reference to diseased animals, with the detail of inspectors of the Metropolitan Board of Health. The results of those inspections were reported to the Board of Health on the 22d day of September in detail.* September 2Uh. A dead steer was sent to rendering dock from Bull's Head, that was found dead in the yard, having arrived from Albany the day previous. He was examined on the 25th at the dock. September 2Qth. Quarantined sixty-nine head of Texas cattle at Bull's Head, owned by Henry Livingston, looking badly; some suspicion of disease among them. They were released on the 28th, finding none sick. * This day removed to hospital three steers, one white, owned by Westheimer & Myers; released on the 28th. * An abstract of the report here referred to, is published in the report of the Metropolis tan Board of Health for 1868. See Appendix. State Agricultural Society. 1039 Same day, two more, red and white, belonging to Mr. D. Adler; white, released on the 28th. Slaughtered a red steer at Bull's Head, owned by Mr. V. Samuels, valued at forty dollars. Also slaughtered another steer at same place, owned by David Adler. The first steer had been sick in hospital for several days, and his temperature taken as follows (he had a persistent cough, dullness on percussion over the lungs with submucous rate): Temperature Observations. Morn. Noon. Evening. 23d 105 o 104 o 24th 103|O 104 o I04^o 25th 102|O 104F 103 o 26th 103F Slaughtered. Temperature of blood at slaughter, 105° F. Lungs adherent to pleura; pneumonia in both lungs; pleuro-pneumonia, old phthisis, and also the peculiar lesions of convalescents from Texas disease in liver, spleen, abomasum and rectum. The second case examined was slaughtered in the dying state, and presented typical conditions in all the internal organs. Prof. Law, of Cornell University; Dr. Harris and Dr. E. H. Janes, of the Metropolitan Board of Health; the artist, Mr. Kohler, and many others were present. Bullock No. 1. Killed at Bull's Head, September 26th, at 2:10 p. m. Temperature of liver, eighteen minutes after death, lOSj^; weight, 23^ pounds. Spleen very large, "weighing 8 pounds 14 ounces, and its length 2 feet 6| inches and 8 inches wide. The duodenum inflamed and oedematous through its whole extent, and its mucous membrane soft — so soft that it was scraped off by lightly passing the nail over it. The ductus communis choledicus, on opening, was found to be inflamed through- out, and having longitudinal bloody streaks like fresh ecchymoses of blood ; at one point was found what seemed to be a little ulcer recently sloughed. One kidney weighed 2 pounds 13 ounces; the other, 2 pounds 14 1 ounces. These viscera were sketched, on the spot, by Mr. Kohler. The blood and bile were subjected to chemical analysis. No. 2. Temperature of blood of aorta, at death, 1051°. Temperature of livei, "fifteen minutes after death, 106° ; the liver was but little above the normal size. The spleen weighed 2 pounds and three-quarters. The bile presented only slight characteristics of the disease. The conclusion was that this bullock was conva- lescent when attacked with pleuro-pneumonia. The disease in the chest was very extensive, and would necessarily have proved fatal in the course of a few days, owing to the great effusion in the pleuritic cavity. JSeptember 27th. Visited Communipaw with Professor E. Law, 1040 AnnujLL Report of New York Drs. E, Harris, E. H. Janes, and others, and witnessed the slaughter of several Texan cattle. Dissections of ordinary Texas cattle, at Communipaw, September 27th, that presented an unhealthy appearance while living: Bullock No. 1. Estimated gross weight of bullock, 1,500 pounds. Temperature of blood at slaughter, 100°. Abomasum : folds normal in appearance, presenting a few slight recent abrasions in the lower section of the folds, and a few old cica- trices. The pyloric portion, like the folds, normal in color, soft, marked exten- sively over the whole tubular section with cicatrices and old sloughs, most of them extending longitudinally upon the rugaae. The length of the cicatrices varies from an inch and a half to a quarter of an inch, a few not yet covered with epithelium. The spleen normal. The rectum perfectly healthy. No. 2. Spleen large, but natural in appearance. No. 3. Spleen rather large, though healthy in appearance. The abomasum — color of mucous membrane normal. No. 4. Spleen rather large, and darker than natural. Extensive old cicatrices of the abomasum, about one-sixth of the whole tubular portion marked with these cicatrices. No. 5. The abomasum — the color of the mucous membrane over the folds rather darker than natural ; mucous membrane soft, but untouched by any disease, so fer as its present appearances are concerned. The tubular portion, covered over about one-fifth part of its surface with cicatrices ; only a few of these have yet received an investment of epithelium. No. 6. The abomasum : very similar to that of the others, with congestion of the folds, presenting cicatrices and a few sloughs near the pylorus, one of which had extended down to the muscular structure, much contracted in circumference, heal- ing not yet completed. No. 7. Shows no evidence of having suffered from the disease. The abomasum showing venous engorgement. Spleen smaller than in actual disease. No. 8. Abomasum shows the common erosions with black surface. The pyloric portion exhibits the erosions, but somewhat more convalescent than the others. No. 9. Temperature of blood at slaughter, 102°. No. 10. Temperature of blood at slaughter 99°. The ductus communis chole- dochus was examined and found thickened. The abomasum contained some extensive erosions; some in the pylorus. The spleen vvas contracted in shape and very dark colored. No. 11. Abomasum exhibits highly congested venous engorgement, with exten-~ sive old erosions; extensive cicatrices of the pyloric portion. These eleven post morteras were made for the purpose of wit- nessing the condition of the viscera, etc., in a herd that had arrived by way of Abelene, Kansas, and which had been pastured for two months in Illinois without any discoverable signs of infection of State Agricultural Society. 1041 disease, except that a few of the steers had a sickly and emaciated appearance. September 28th. Inspected cattle at Bull's Head; released 69 bead of Texans, belonging to Henry Livingston, in quarantine for two days. October Qth. In examining cattle at Bull's Head, found a white ox in yard, belonging to S. B. Richardson. He came from near Lafayette, Indiana, in a drove of 174 head bought of Clafner, at Buffalo; 57 head came to New York, and 117 went to Bergen, New Jersey. When found, this ox lay groaning in distress; rectum protruding, very red; making constant and painful efforts to defa- cate, without being able to pass anything; restless, lying down and rising frequently, going to the trough for water every few minutes. Removed to hospital; temperature 1041*^. He was kept under observation; recorded the following temperature, Fahrenheit scale: October 6th 1041° do 7th 104|O do 8th 104|C do 9th 1041° do 10th 103F do 11th 1030 The owner supposing him to be suffering from constipation (he did not chew any cud during the six days), was allowed to treat him as he desired. Injections per rectum of various kinds were resorted to, but without relief. On the 11th October, showing evident signs of collapse, he was valued at $40, and slaughtered, in presence of Drs. S. Smith, E. Harris, E. H. Janes, F. J. Randall, and myself, together with Mr. Kohler, the artist, and many others. The notes upon this case, taken at the time of slaughter, are as follows: Respiration 26 per minute. Temperature of rectum, 1031°. Slaughtered at eight minutes pastil, a.m. Temperature of blood flowing from aorta, 101°; temperature of rectum, 1001°; temperature of liver, 100°. Specific gravity of blood, 1.055. For fifteen minutes after death, the blood from the aorta remained fluid ; began to coagulate twenty minutes after flowing from the aorta. Spleen, 2 pounds 11| ounces. Liver, 18 pounds 4 ounces, divested of the bile and gall bladder. It appeared fatty throughout. (Subsequent examination proved that, like the liver of the bullock that was slaughtered on the 26th September, the inorbid alteration consisted as much in a "waxy" degeneration, as in the fatty deposit.) Minute biliary vessels visible everywhere, the color resembling "cafe au lait" of an ochre hue. This is one of the few chronically diseased cattle that, after ineffectual attempts [Ag.] - JoQ 1042 Annual Report of New York at convalescence, became deeply jaundiced and angemic. The spleen, the liver, the blood, the bile and the fatty and cellular tissues bear unmistakable marks of the disease. Dr. Harris had the artist sketch the morbid appearances. (See plate 23 in General Report.) This was a typical case of the Texas disease, and revealed a large mass of cellular tissue around the rectum, and in which the kidneys were imbedded, which upon microscopic examination revealed an abundance of hfematoidine crystals. October 11th. Three steers found sick; two of Bright and Fagan's, and one of Williams and Richardson's; removed to hospital. TEMPERATURE RECORDS as follows : Date. Lop Horn. —B.&F. Spotted. — B. &F. Crumple Hor^t. W. & R. Oct. A. M. M. p. M. A. M. M. p. m. A. M. M. p. M. 17th 18th 19th 20th 21st 22d 23d 24th 1011° 1001 100 100 101 ° 101 lOOi 100 ° 100 1001 1011° 101 101 100 100 100 100 99 101 ° 101^ 101 i 101^ 101 101 991 100 102° 101 102 "99" 100 98 released. 1041° 1041 104 103 1031° 103i 1031 1001 102 ° 102 103^ released. On the morning of October 17th, a fine fat bullock was abandoned near the National drove yards, and was carried to* the rendering dock, and slaughtered during the afternoon. Tlie animal was slaughtered when in a moribund condition. Temperature of rectum, blood, and of the liver was one hundred and one and a half degrees; weight of liver, twenty-four pounds; gall bladder filled with thick flaky bile; weight of spleen, five and three-quarter pounds, dis- organized; bladder filled with bloody urine; rectum contained a thick, black fluid, resembling black vomit; the fourth stomach was eroded and ulcerated; the kidneys were engorged to seventy-five per cent more than their natural size, and were beginning to be disorganized; lungs were healthy; no coagulated blood was found in the heart or great vessels. From October 17th to- 22d, daily inspections of all cattle arriving were continued; no new eases found. 22d. Commissioner Gould having learned some facts with reference to a dairy herd that had become infected at Hamptonburgh, Orange county, desired me to go with him and prosecute an investigation into the circumstances.* * Dr. Montfort, the liealth oflacer of Newburgh, who had been vigilantly watching the movement of suspected cattle arriving at that city. from Albany, unexpectedly discovered State Agricultural Society. 1043 "We, therefore, proceeded to Newburgh, and were joined by Dr. R. V. K. Montfort, the Assistant Commissioner for Orange county. We then visited Goshen, and from thence went to Hamptonburgh, where the following facts were elicited: On the 25th day of August, there arrived at Hamptonburgh, Orange county, N- Y., forty-four head of native cows and heifers directly from Paiuesville, Lake county, Ohio, on the line of the Lake Shore road, over which Texas cattle frequently travel. They were purchased in BuiFaio for a Mr. Hodge,- a cattle dealer at Goshen, Orange county, N. Y. On the morning of arrival one of the cows was observed to be unwell, and died in a few hours. The symptoms observed were as follows: "The head hanging low down, gait staggering; appeared very weak, and finally fell down, death supervening soon afterward." August 29th (four days after), two cows were purchased of the same lot by Wm. Moul, apparently well. They were driven about six miles, and were turned into the pasture among the dairy cows of Mr. John Moul. Here they remained from ^Saturday, the evening of the 29th, until Tuesday morning, the 1st of September (three nights and two days), when they were removed some miles distant. September 8th, one of these cows died. The other was then taken back to Hamptonburgh, the place of purchase, as under suspicion, and on the 10th of Sep- that the Texas cattle disease had made its appearance on the southwestern margin of that county, near Hamptonburgh. The following is his first account of that outbreak : ''Newbtjegh, September 11th, 1868. •*' E. Harris, M. D., Metropolitan Board of Health: " Dear Doctor — Two ear-loads of cattle (forty in number), said to be from Ohio, were purchased at Montgomery, in this county, on the 28th day of August, and were driven some five or six miles, to Hamptonburgh, the same morning, arriving about 9 or 10 o'clock. Soon after, one of the finest cows in the herd was taken sick, and died before night. Two of ttie herd wer-e ijought by William Moul, a neighboring farmer, and were left three «r four days upon the farm of John Moul, grazing with his dairy cows. They were then removed. Ten days after their purchase, one of these cows sickened, and died in a few hours. Thre« days iater, the second cow also sickened and died in a few hours. Satur- day, September 12th, one of the cows of John Moul was taken sick. She died on Sunday. Monday night another cow of John Moul sickened, and died Tuesday afternoon. Both of these had grazed with the two left for a few days by William Moul. The remainder of John Moul's cattle are still healthy. Fifteen bullocks, out of two car-loads, are yet ia the neighborhood — aU well. Two were purchased by a Mr. Carroll; one is well, the other sick; appears very weak, pants heavily on the least exertion, gives milk, but in small quantities; feeds poorly; had a calf two weeks ago. The owner says she never cleared, and ascribes her illness to that cause. Eleven of the same load were sold to a farmer near Montgomery, and when last heard from were all well. I know nothing of the balance (9). Hamptonburgh is an old cattle stand, where a large part of the farmers of that portion of Orange county purchase their stock. Yours, truly, (Signed) "E. V. K. MONTFORT." 1044 Annual Report of Nmv York tember also died. The symptoms of disease of this cow were recognized as the same as those that had been seen among cattle at Buffalo that had died with the " Texas fever," and were as fol- lows: "Drooping of head and ears; staggering gait; eyes dull and staring; great debility; rough coat, and generally such appearances as are not observed in the ordinary diseases of cattle " with which they had been familiar for years. Upon tracing what had happened from the exposure of the dairy cows upon John Moul's farm, where these two cows had been pastured for a short time, we found that upon the 12th of September (thirteen days after exposure), one of the milch cows was found to be ailing. Her milk had been falling off in quantity for three or four days; she appeared uneasy, fre- quently lying down; very thirsty; would not feed; head drooping near the ground; standing braced with the hind legs; coat rough, dung natural, urine not noticed; no cough, and on the night of the 13th died. On the 14th (fifteen days after exposure), another cow •was observed to be sick, presenting symptoms the same as the former, with the addition that she seemed indifferent to passing objects, remaining alone by herself, and passed bloody discbarges from the bowels, and dark, bloody urine; milk entirely suppressed, although she gave the usual quantity the night before. She had been suffering with hoof distemper three weeks previously, but had entirely recovered from it. She died on the 15th (the follow- ing day). The 18th of September (nineteen days after exposure), the third cow was sick, aiid during that day was found dead in the pasture. Pier milk had been diminishing in quantity three or four days previous to death, and she had presented much the same symptoms as those previously affected. These cows unfortunately were not examined after death, but were deeply buried. The two cows that had died of the original herd were not buried sufficiently deep, as during the process of decomposition after death, the thin covering of earth was thrown off, leaving the carcass of one of them exposed. Two pairs of oxen and two young heifers were allowed to pasture in this field where the dead cows were buried, and one of the pairs of oxen was used in "hauling the dead cow. About two weeks after, one of the oxen was found to be sick, and presented the same symptoms before described, from which, how- ever, he finally recovered. Another ox belonging to the second pair was found dead, on the 21st of September,^ in the field, being twenty-eight days from the burial of the first cow. October 24:th. The two heifers, one a yearling, the other two State Agricultural Society. 1045 years old, which had been pasturing in the same field where Iny the dead cows, and where the oxen were sick also, were found dead. They had not been discovered to be suffering with any illness. A post mortem examination of these revealed the livers enlarged; spleens enlarged more than twice their natural size, engorged with blood, in a state of decomposition; kidneys engorged with blood, softened almost to decomposition; bladders containing a very small quantity of urine of a healthy consistence. All the other organs were found in a healthy condition, except the aboma- sums, or fourth stomachs, which presented several superficial ulcers upon the thick or pyloric extremity, as well as some lines of ulcer- ation among the folds of the thinner portions. The carcases, after examination, were thoroughly burned up. From these investigations, which were carefnlly and thoroughly made by the State Commissioner, J. Stanton Gould, and Assistant State Commissioner, Drs. R. V. K. Montfort and Moreau Morris, there can be no doubt that the drove originally from Painesville, Ohio, had been infected with the malignant poison, either before starting or during their journey, and that they had communicated the disease to the dairy cows and oxen at Hamptonburgh. These dairy cows had not been off from the farm of Mr. John Moul for the past two years, and had not been exposed to any strange cattle at any other time. The oxen had been in the town and county for several years, and had not been exposed in any other manner. That these cattle had the "Texas fever," all the testimony of per- sons who had observed them, and by one who was familiar with the symptoms, having frequently seen cattle suffering with the dis- ease at Bufialo, must convince any candid mind. The remarks of several persons (old dealers in cattle) that these sick ones did not appear to have any disease with which they had been familiar, afforded another proof, that this was an importation of some new and malignant disease among them. Two more milch cows died, one on the 26th and the other on the 28th October. The subjoined letter from Dr. Montfort, gives the history of these cases: ' Newburgh, November 9, 1868. Moreau Morris, M. D. : Dear Doctor — We have had two new cases of Texas fever since I saw you. The first case after you were here occurred on Monday, the 26th of October. She was observed to be sick on Monday, with the usual premonitory symptoms, although they were so slight as readily to escape the observation of a casual observer. She gave a fair quantity of milk at night. She died about 7g A. jr., 1046 Annual Report of New Yojrk Tuesday. A post mortem made about eight hours after death gave the following results: Flesh very dark; fat of reddish yellow color ; lungs perfectly healthy; heart healthy ; spleen enlarged to three times its natural size, engorged with blood and disorganized; liver slightly enlarged and fatty; gall bladder very full, con- tents but little changed ; kidneys natural ; fourth stomach reddened and inflamed, particularly at pyloric extremity, with ulcers ; mucous coat softened, peeling off . readily ; bladder entirely empty and contracted, feeling almost like a ball ; rectum very much inflamed; mucous membrane softened. The period of incubation could not have been less than thirty-five days. Another cow died on Wednesday night, October 28th. She was first seen to be sick in the morning. Nothing particular was observed, excepting the arching of the back, and great restlessness. No post mortem. Yours truly, (Signed) R. V. K. MONTFORT. REMARKS UPON THE CASES IN ORANGE COUNTY. This remarkable group of cases in Orange county justly awakened a profound interest, and induced the most searching inquiries con- nected with the history and exposure of the herd in which these deaths occurred. The exceptional characteristics presented by the sickness in those herds, called for the most exact diagnosis of the nature of the disease. First — Cattle that were supposed to be natives of the Western States, and that had arrived from Paines- ville, Ohio, in the ordinary course of traffic and transportation, began to show symptoms of disease within a week from the time of their shipment from Painesville, Ohio. The true Texas cattle dis- ease, as has been shown in Dr. Harris' correspondence, was at the time prevailing in Summit county, Ohio. That these cattle, which w^ere at least reputed to be native stock, and communicated the disease to the healthy herds of the district with which they were pastured in common, did communicate the same kind of fatal dis- ease that killed several of their own number, does not admit of the shadow of a doubt. In the absence of those exact methods of investigation which the medical anatomists pursued in our cities, we do not hesitate to take the straightforward testimony of expe- rienced herdmen who saw the disease and described it to us. In the two post mortem examinations which Health Officer Dr. Montfort and I made at Hamptonburgh, in the month of October, we were able to recognize the disease by the usual post mortem evidences, and better still, by the particularity and completeness with which the entire history of events and symptoms of these cattle were related to us. Here was the history of eight fatal cases of the Texas cattle disease in three diffisrent herds, in which no ground of doubt existed, that exposure to the Western cattle con- State Agricultural Society. 1047 stituted the starting point and source of the disease; and viewing these eight cases purely upon medical evidence alone, we might safely conclude, reasoning by exclusion, that the Western cattle l)rouo;ht the disease into these herds. The points we would notice specially in these cases occurring in Orange county are: 1st. The evidence concerning the period of incubation, gives an interval from fourteen to twenty-eight days. 2d. From careless and imperfect burial of dead diseased cows, the infection was communicated to other healthy native stock; and 3d. That the evidence of the contagion of the Texas cattle dis- ease being communicated from native to other native cattle in this group, is beyond a doubt. THE INVESTIGATION INTO THE HYGIENIC CONDITION OP BEEF CATTLE OFFERED TO THE METROPOLITAN MARKETS, AS FOUND IN THE SLAUGHTER HOUSES AT A PARTICULAR TIME. Numerous facts having come to the knowledo;e of the Board of Health, concerning diseased meat being oftered for sale in the public markets, a simultaneous inspection at a large number of slaughter houses during the slaughter of cattle, for a limited period, was deemed necessary. On the 15th day of September, the following order was issued to eleven sanitary and assistant sanitary inspectors of the Board: ICopy.-] Metropolitan Board of Health, 1 New York, September 15, 1868. ) To Dr. Moreatj Morris, Sanitary Inspector M. B. H. : Sir — I have called upon the acting Superintendent of the Metropolitan Board of Health, Dr. Horatio Paine, to call together a force of inspectors, twelve in number, viz : Strang, Howard, "Wadsworth, Demainville, Randall, W. V. White, Lee, Janes, Thayer, Fisk and Colton, and Deputy Registrar Stiles, to meet at this office at 11 o'clock to-morrow, September 16th, for special duty of inspection, subject to your special direction, upon the matter of diseased cattle and diseased meat in our midst. You will proceed with this inspection at once, and report. Yours very respectfully, (Signed) GEO. B. LINCOLN, President Metropolitan Board of Health. The following named gentlemen were thus detailed: Inspectors Drs. Janes and Lee, of New York; Dr. Fisk, Thayer and Colton, of Brooklyn ; assistant-inspectors Drs. Howard, Strang, White, Wadsworth, Demainville and Randall, of New York; and were directed under specific instructions and uniform methods, to make 1048 Annual Report of New York examinations at the different butcheries in their respective districts. All proceeded at once to the dock of the New York Rendering Company, foot of Thirty-eighth street, North river, where an animal sick with the Texas cattle disease was slaughtered in their presence, and carefully dissected. Illustrations of the specific lesions of the disease, which had been made from previous dissections of slaugh- tered animals, were also exhibited to them, with explanations, so that their examinations could be made understandingly. The investigation was continued for three days consecutively, with the following results: Two hundred and ninety cattle were slaughtered in their presence, and of these, two hundred and thirty-six presented evidences of dis- eased conditions. The viscera of many others which had been slaughtered upon the same days, but at whose slaughter they were not present, were also examined carefully, and found to present evidences of the same conditions. With two exceptions, all reported findins^ abundant evidences of different conditions of \^ above the natural heat of healthy bullocks — that standard being 100° Fah., or a fraction of a degree below 100° — was not followed within four days by the unequivocal evidences of the cattle disease. The first observations upon this point were commenced on the 8th aiid 9th of August, in Mr. Alexander's infected herd at Commu- nipaw, and on the 11th and 12th, temperature observations were made upon five of the cattle that exhibited symptoms of the dis- ease in Mr. Thomas' herd at Bergen, with the following result: The one least sick in appearance had a temperature of 104°, while one that was staggering and delirious with the disease, had a tem- perature of 109°; another, delirious but not staggering, 107^°; another, lOT^*^; and another, very feeble, 105°. On the 13th of August, the animal that was delirious and staggering twenty-four hours previously, and now unable to walk, had a temperature of 106° in the rectum, and 106^° in the blood of the aorta at the moment of slaughter. The other bullock that had a temperature of 107^°, was found in a dying condition on the 13th, and had, a State Agricultural Society. 1099 moment before slaughter, had a temperature of .107° in the rectum, and 107|° in the blood of the aorta at the time of slaughter; while that bullock which, on the 12th, had a temperature of 105°, was found to be in a dying condition, and had a temperature of 106° in the rectum and the blood of the aorta at the moment the vessels of its neck were severed. Persons who did not witness the disease, might reasonably inquire if this feverish temperature was not the result of inflammatory action or excessive irritation, incident to the hardships of transpor- tation; and this was a question which the committee caused to be thoroughly investigated, with reference to cattle that were arriving under the circumstances, and at the same time obtained in reference to the sick herds; it was proved that the temperature of all cattle, excepting the victims of this infection, gave evidence of but slight increase of temperature under any circumstances, and that an increase above 103° Fahrenheit, was not observed in any other than infected bullocks, and that there were only three or four instances in which the uninfected animals steadily exhibited a temperature above 101°. The average of all the temperature observations taken of the infected bullocks was nearly 105°. The mean temperature of the central part of the liver, taken from ten to fifteen minutes after the animal ceased to breathe, was 104^°.* (2.) Evidences of toxaemia were early observed to be among the very first symptoms of the obvious stage of the disease, constant unrest, a faltering gait, a partial paralysis, occasionally a kind of paraplegia, the sick animal in such cases reeling or actually falling down upon his hind-quarters; and in some instances, the urinary bladder remaining distended and almost continually leaking as by a kind of enuresis, the symptoms in short being those which pertain to failure of innervation, in consequence of some kind of poisoning, or from some fatal change in the condition and chemistry of the blood. But chief among this group of symptoms is the disturbance of the senses, and the occurrence of a kind of delirium. Further details of this class of symptoms need not be mentioned here. The evidence of the operation of a morbid poison is the subject to which attention is invited; and, whether this poison be derived from an external source, as some kind of contagious matter, *The practical utility of thermometrical observations has been strikingly illustrated in the dealings which the sanitary officers have had with cases of the Texas cattle fever. The pestilential type of this fever was unequivocally asserted by this test alone, even in cases in which the obvious symptoms had not yet appeared. 1100 Annual Report of New York for example, or some parasite, or whether it chances to be a pro- duct of morbid changes in the proximate elements of the circu- lating blood, the fact that such a condition of empoisonment occurs, is important and suggestive. (3.) The evidence of dissolution of the proximate elements of the blood appeared in a special group of symptoms as well as in certain general phenomena. The " black water," or hsematuria is the con- stant symptom of the breaking up of the blood globules; while the marvelous increase of temperature in the infected animal, the ecchymoses and engorgement of nearly all vascular organs and tissues, such as appeared in nearly all the cattle that died or were condemned, must be regarded as general symptoms. The bare fact that a destructive disorganization of the blood was not only the invariable result in all the cattle that died or were slaughtered in consequence of the malady, but that wherever the infection was introduced among herds, the farmers and common observers recog- nized the disease by the term "black water," or " bloody water," shows how invariable was this pathological change. To ascertain the causes and the history of these destructive changes in the blood would be almost equivalent to gaining access to the entire line of the facts which are concerned in the causation of the disease. Hence the class of symptoms here mentioned, together with the minute and general changes which the tissues of the infected animal suffered in consequence of the changes in the blood, and especially certain morbid conditions of the liver, the bile and the spleen, that would morbidly affect the blood, became the objects of special study. The researches of the micro- scopist and the chemist were of the highest service here. And there is reason to believe that the very discriminating study which these scientific experts bestowed upon the questions that were sub- mitted to them in regard to the physiological and chemical events concerned in the spoliation of the blood, will be among the most permanently useful labors of the whole investigation. The symp- toms and phenomena that indicated these destructive alterations in the blood were worthy of the distinguishing importance that has been attached to them both by the herdmen and medical men. - (4.) The careful examination of the flesh and all the organs of beeves that came under suspicion in various abattoirs, with regard to the healthful conditions that might be discovered in such meats. This jpost mortem observation very frequently was resorted to by Sanitary Inspector Morris, as a means of verifying or of correcting State Agricultural Society. 1101 opinions or suspicions that were based upon slight or equivocal symptoms in the living cattle, or upon equivocal records of the herds. As will be seen in Dr. Morris' special report, there were numerous instances in which the opportunity for the observation and testing of symptoms in living cattle that were under contract by butchers, was so unsatisfactory, that the post mortem observa- tion of the carcass and its viscera was deemed important. The fact should be stated here, that these post mortem observations — and we now refer to the mere inspection of the carcass and the abdominal viscera — so completely confirmed the trustworthiness of the thermometrical observations and the special symptoms of the advanced or obvious stage of the disease, that Dr. Morris finally relied exclusively upon the self-registering rectum ther- mometer and his own personal inspection, during the most trying periods of his service as Assistant Commissioner for the State. When it is considered that the latent or incubative period of the disease is protracted through several weeks — always more than fourteen days — and that the temperature test never was resorted to in vain when a doubt existed, and that the post mortem inspec- tion of several thousand beeves, by Assistant Commissioner Morris and his aids, lent full confirmation to the conclusion that increased temperature was the first, most constant and sure of all means for ascertaining the existence of the disease at any stage in which its presence and effects can in any manner be ascertained, tlie import- ance of the records of temperature will be conceded. (5.) Lastly, the observation of the symptoms of recovery or con- valesence became important in the study of the disease. The opportunities for such observations were rare indeed. The five sick bullocks that were given up to us by Mr. J. T. Alexander, for observations and medical experimentation, as well as for ultimate anatomical examination, were too wild and timid to allow of satisfac- tory observation of the temperature and other intimate symptoms daily. Greatly as this circumstance was regretted, in these most instructive cases, the general observations upon the progress of those cattle towards recovery will be perused with interest. They are recorded in Dr. Morris' contribution to this report. It will be noticed that the temperature of the first of that group of convales- cents, at the date of his slaughter and on the seventh day of con- valescence, was 103|° Fah. This is precisely 3° less than the temperature observed in the same bullock one week previously, 1102 Annual Report of New York ■when he was passing bloody urine and exhibiting all the symptoms of the advanced or obvious stage of the disease. Thouafh the five infected bullocks here mentioned constituted the only group of convalescent cattle without complications, which were observed throughout the entire period of recovery, or from the commencement of symptoms of recovery until the end or until slaughter, there were numerous instances (in all about thirty cases) in which bullocks were brought under Commissioner Morris' official observation, when in some stage of partial recovery that had become seriously complicated by excessive or incurable lesions, or by fever and fatal prostration, in consequence of the severities of hurried transportation. If the medical reader of this report will turn to Prof. Chandler's tabulated analyses of the blood of some of these convalescents, the state of the blood in the instances here referred to will be seen to account for the fatal results which ensued in convalescent cattle when subjected to the hardships of transporta- tion or. to dry food, etc. • We have referred to the recovery of five cattle under very favor- able hygienic care and antiseptic medical treatment at Communi- paw. And it is proper that we should express the conviction we entertain that every one of them would have died in a very few days if they had been driven to the butchery sheds in the heart of the city and there put upon hay diet and hard usage. We beg leave here to append the latest statement from Dr. Snow, superin- tendent of health in Providence, concerning the ultimate result of his observations in the case of the convalescent and imperfectly cured bullocks that were under his official direction, and concern- ing which we have given some account in a preceding section of this report. The group here referred to fell sick on arriving at Providence, the first week in August, and the owners promised the medical officer that he should see the survivors at slaughter, some time in December, if they recovered flesh by that time, as they had no doubt they would before the expiration of five months. As Christmas week was the time designated for the slaughter and examination, we have waited until the printing of this report has been commenced. Under date of January 7th, 1869, Dr. Snow writes: * * * In relation to those cattle which were sick last summer, I am informed that they have not grown fat, and are unfit for beef. It is, therefore, yet uncertain when they will be killed. The promise is continued, and I presume will be remembered, that when it is proposed to kill them, I shall have due notice and opportuuit}'' to examine them. State Agricultural Society. 1103 It will be seen from these records relating to medical observa- tions upon convalescent cattle in this disease, that like all other observers of the malady, the assistants of this committee came well nigh losing all opportunity of studying the phenomena and history of convalescence. Fortunately we had some rare chances for this class of observations, and they were improved. But had it not been for the unceasing watchfulness of Assistant Commissioner Morris, who permitted no suspected bullock to escape his personal inspection, ^aud the test for the temperature and other symptoms, some of the most instructive illustrations of the disease would have remained unobserved and mirecorded. The explosive suddenness with which the fatal stage of the disease occurs, the rapidity and brevity of that stage, and the readiness with which the dying ani- mals could be, and for a time were, sequestered, or abandoned unclaimed, and — most important of all — the rapidity of the putre- faction that immediately ensued upon the death of the diseased bullocks, rendered it a difficult and vexatious task to carry out the plan of searching investigation we had adopted. Distance, Aveariness, hunger, storms, the rapid transportation, and the quick assembling of all the necessary assistants in each post mortem examination, were very essential means to the successful results that attended these efforts. Such has been the history of our efforts to secure a reliable series of medical observations upon the Texas cattle disease. These efforts were necessarily made under circumstances of very great incon- venience, in open yards or pastures, upon wild and timid bullocks, with no skilled aids to trust, except the few overworked medical officers whom we have here mentioned, and with only an occasional opportunity to continue the observations for more than thirty -six hours in any one case, — so rapidly fatal was the malady in its stage of obvious symptoms. Imperfect and incomplete as the series of observations continued to be, untiring endeavors continued to be put forth to correctly observe the essential symptoms of the disease in each group of infected cattle that came within reach of the medical officers who had undertaken this inquiry: and it was by persistent and unvarying adherence to the original purpose and plan of the observations that anything worth having was ultimately accomplished. The total results of the medical observations may, therefore, be summed up as follows: (a.) The duration of the period of obvious symptoms of the disease is brief, and so far as our observations and other reseai'ches J 2 04 Annual Report of New York can be said to have determined anything in regard to the onset and progress of this short and last stage of the mahidy, it seems not only to be a paroxysmal stage or period of the disease, but like- wise seems to be a single paroxysm. That is, the Texas cattle dis- ease, considered with reference to its obvious symptoms, is a fever of but one paroxysm* (b.) The symptoms come on, at first, in so sudden and violent a manner as to have led to the remark in every group of cases we have witnessed in Northern (native) cattle, that the obvious mani- festation of the malady comes, as the French say, "^ar explosion,''^ or with suddenness and violence. (c.) The symptoms, as well as the observations that have been made in the numerous post mortem examinations at all stages of the disease, plainly declare the fact that the destructive or disor- ganizing changes which occur in the proximate elements of the blood, and in the special degenerations of tissue in the liver and spleen are very rapidly produced, and that the logical evidence is clearly in favor of the hypothesis that the structural lesions which ensue in this malady mainly occur during the obvious brief period of symptoms. But the symptoms do not yet reveal the extent of the congestive and other changes that may be going on in the liver, stomach, spleen and kidneys for weeks previous to the explosive or phenomenal and obvious stage of the fever. Such morbid con- ditions are reasonably inferred by other than the symptomatic evidence. (cL) The symptoms connected with the appearance, posture, res- piration, pulse, successive changes in the progress of the fatal or obvious stage of the disease, as all that i^indicated by the temper- ature changes, and by the phenomena attending the death of the infected cattle, completely harmonize in the conclusion that all these symptomatic conditions indicate the rapid and fatal operation of a morbid poison, or a combination of poisonous agents. And further, it is demonstrably certain that the mvasion of the blood or blood and tissues by that poisonous agency is rapid, and compara- tivel}', that it is sudden; or, that the powers of life do succumb to its morbid power very rapidly and suddenly. So clearly was this * The medical reader of this report need not be reminded that this peculiarity in the type and phenomena of the Texas cattle disease renders it strikingly analogous to yellow fever in man. And it should here be remarked that the observations of Dr. Ranch and Mannheimer, in the infected cows at Chicago, establish the fact that the obvious or last etage of the disease is ushered in by a chill. State Agricultural Society. 1105 fact indicated in our earlier observation of the sjaiiptoms and phe- nomena of the disease, that it led to very scrutinizing search for the morbid came by means of the microscope and chemistry. In other words, the symptoms guided and impelled us to those exact researches which were subsequently made in regard to the patho- logy and causes of the disease. This has been, therefore, a strictly medical and logical kind of investigation, from fii-st to last. THE SLAUGHTER AND POST MORTEM EXAMINATION OF INFECTED CATTLE. This duty was deliberately undertaken, as was noticed in the first section of this report, as soon as permission was obtained. The task was, in all cases, an unpleasant, toilsome and expensive one. It was not a self-imposed task, for it was a duty. Familiar with the history and requirements of the more exact methods of pathological and medical investigation, the Sanitary com- mittee and medical officers of the Board of Health foresaw many diffi- culties which they had reason to fear might prevent success in the -effort to push such investigations as were essential. 1st. The sud- denness of each discovery of the sick bullocks b}^ the Sanitary Inspector and State Commissioner at the herd yards, and the rapidity with which the fatal stage of the disease ensued, rendeved it diffi- cult to make arrangements for a post mortem in season to find the animal alive at a suitable hour for the inspection. 2d. It Ava« deemed essential that everything pertaining to the post mortem investigations should be attended to immediately after killing the diseased animal, and this involved great sacrifices of time and con- venience, besides much cost and vexation. 3d. It would almost certainly be found impossible to make perfect w^ork in all the needed branches of investigation, and some points would necessa- rily be omitted. The importance of the researches seemed to justify the attempt then, and as the medical members of the Board that constituted the sanitary committee, advised the efifort to be made, the duty was plain. But in presenting the chief results of the effort, it is due to all concerned that the fact should here be stated, that the ability or means for prosecuting all this kind of labor depended upon the voluntary labor and sacrifices by two or three persons who greatly desired to see the whole work and responsibility assumed by other hands. From beginning to end this class of investigations required infinite toil, patience and rigid regulations for its execution.* . [Ag.] " 70 1106 Annual Report of New York The various sketches which have been prepared in chromo- lithography, to illustrate and explain this report upon the disease, have been executed with great faithfulness. They are especially valuable as showing precisely what lesions occur, and by what dis- tinctive marks and colors they are distinguished at the hour of the slaughter and death of the sick bullocks. In the selection of examples for these sketches of the pathologi- cal changes in the disease, there was a careful avoidance of all exaggerated cases or excessive alterations. It was deemed useless to attempt to sketch for printed illustrations, any of the excessively marked results of the disease; for example, the cases in which the kidneys had become disorganized, or the spleen had become a mass of diffluent pulp, or, as was occasionally witnessed while the bullock yet lived, the tissues being inflated by the gases of putresence and decomposition. The sketches relate solely to the average classes of cases of the disease. They were all animals in good flesh and full development, excepting only a few convalescents that were, of course, emaciated by the continuance of the disease. The first fact that impressed the medical officers concerning the morbid changes produced by the disease was, that the putrefactive process was in full operation almost immediately after death, whether the death was by the pole-ax and knife, or by natural exhaustion. It was all-important, therefore, that whatever post mortem inves- tigations were made, should be attended to in slaughtered bullocks, and instantly after life had ceased. That this tendency to speedy decomposition was not due to peculiarities of the weather, or to any other cause than disease itself, would plainly appear from the fact that the cattle, horses and other animals that daily died in the Metropolis from other causes, did hot undergo such rapid decomposition, nor, especially, did any of their viscera undergo such putrescent disorganization as was found to be the rule in regard to the kidneys, the spleen, the liver, and the fluid blood of the infected cattle. As mentioned elsewhere in this report, these fer- mentative (zymotic) changes were, in some instances, so fully estab- lished before the dying animals had ceased to breathe, that it was found in the dissection which instantly foUawed the slaughter, that putrescent disorganization was already in progress in the viscera here mentioned, and that gases, resulting from the general decompo- sition, already filled the capillary blood vessels and the surrounding tissues. The second very essential fact revealed in the post mortem State Agricultural Society. 1107 examinations, consisted in the greatly increased size and weight of the liver, the spleen and the kidneys, and in very important patho- logical alterations in the two viscera first mentioned, so important and peculiar indeed, when examined microscopically and with pre- cision, that no ground of doubt now remains that certain of these morbid conditions may justly be regarded as trustworthy guides in discriminating between undetermined causes and kinds of disease in dead beeves inspected at abattoirs, or in cattle when found dead or brought to slaughter. Yet, this kind of pathogmonic evidence found in the liver and spleen by the microscope, is so constantly associated with several morbid changes which are visible to the naked eye and other ready aids to a judgment, that for ordinary- purposes of sanitary and market inspection, the latter can always be relied upon with tolerable certainty. A summary of these con- clusions upon the post mortem inquiries will be found at the end of this chapter. RESULTS SOUGHT BY MICROSCOPY, CHEMICAL ANALYSES, AND THE EXPERIMENTAL TESTS. The practical usefulness of the microscope, however powerful and perfect the instruments employed in the reseai'ches of pathology, is so largely dependent upon the experience, skill, and good judg- ment of the medical observer who uses them, that it is hardly necessary to mention the particular quality of the instrument which Dr. Stiles used in his examinations. But as we have ascertained by correspondence with several good microscopists in Western cities where the disease was being observed, that it has frequently been found impracticable to bring into operation the degree of excellence and power of glasses which Dr. Stiles was employing, we will mention, in his own words, for readers who may desire to be informed on this point, that " the more delicate researches were made with a ' Hartnach immersion system,' magnifying, with No. 4 ocular, one thousand diameters." All who witnessed Dr. Stiles' demonstrations in the field (or the abattoirs) were fully impressed with the remarkable clearness and penetration of his glasses, and with the nicety and skill of his manipulations of the elements that were brought under examina- tion. And as the plan of the pathological researches required that all final conclusions must be based upon results of examinations made of tissues and fluids taken freshly fjom cattle killed and dying in presence of the medical officers directing the investiga- 1108 Annual Report of New York tioiis, there is a trustworthiness in the microscopical and other pathological researches in this inquiry such as has rarely been attained. Numerous cattle that were found dead or that died in the absence of any medical observer, were examined minutely, but the conclusions in this report are based upon none of those exami- nations, though the latter were generally instructive and corrobo- rative in their bearings upon the medical history of the disease. As the microscope had, in skillful hands, during the past few years, revealed the essential character of certain morbid changes that now enable us to determine the nature and name of the fever that has destroyed the life of a person found dead, if the point of inquiry be whether yellow fever or the malignant congestive fever were the fatal disease, and as chemistry had also come to the aid of the physician, in discriminating between various diseases and between different causes of pathological conditions, it was reasonably hoped that some progress towards the ends desired in the cattle disease inquiry would result from the use of these aids. Precisely what results have been reached will be seen in detail in the chapters contributed ])y Dr. Stiles and Professor Chandler. Taken by them- selves, — each fact and each result separately, — the real value and significance of the separate portions of all this work cannot be cor- rectly understood. Therefore we will here present a brief sum- mary of the total results attained in the investigations which have been made. SUMMARY OF RESULTS IN THE PATHOLOGICAL INVESTIGATIONS. I. Concerning the Anatomical Changes or Lesions — Vital Organs that are most Afeected in Structure and Function. — The post mortem inspections showed that the liver, the spleen and the kidneys, the organs which are chiefly concerned in the preser- vation of the blood from destructive agencies, were the most constantly and seriously afiected. No exception was found to the rule that the liver and spleen exhibit morbid conditions and are to be regarded as characteristic evidences of the disease; and the morbid alterations in the kidneys seemed to be incidental to an ■(pssentially pathological condition of the blood. But, as regards the pathological conditions which have been found so constantly as to be justly regarded as attributes of the disease, there were two elements which may not have depended directly upon any primary morbid alteration in the blood; yet it was plain that all these alte- rations should be considered as associated results of some primary State Agricultural Society. 1109 morbid poison, tliat so far iis we could judge by the evidence, ope- rated chiefly upon the blood and the liver in the earliest period of its fatal work. Reasons for this conclusion will appear as we pro- ceed in the pathological records, Avhere the intimate changes that occur in these organs, will be fully described. Gastric Lesions. — The only constant or characteristic lesion of tissues in any portion of the stomachs in the infected cattle was limited to the fourth stomach (^rennet or- cJjomasimi), and this lesion consisted in erosions, sloughs and ulcerations of the mucous lining. These were, in all acute and recent cases, mostly limited to the tubular or pyloric portion of that stomach. Their appearance is correctly shown in plates 6, 7 and 13. The folding and expanded, or omasal portion of the abomasum, though excessively congested and almost purple in appearance in certain cases of the disease, was found sloughed or marked exten- sively by ulcerations, only in chronic or slowly convalescing cases. Plates 3 and 4 show the appearance presented by the cases last mentioned; while plate 4 shows the appearance of the abomasum and omasum in one of Mr. Thomas' Indiana herd, which was slaugh- tered and sketched in the field August 13th, near Hudson City, N. J. It is almost the only instance in which the entire lining mem- brane of the rennet or fourth stomach was wholly unbroken by erosions or sloughs; yet the bullock was in a dying condition when killed. It would appear quite probable that the lesions in the fourth stomach result primarily from intense engorgement and stasis in the vascular structure of that stomach, and that this lesion occurs in the dense fibrous structure of the tubular section, where the sloughing and erosion of mucous membrane have been chiefly observed. Though the constricted or closely adherent relations of the membrane throughout the tubular or " reed " portion of the abomasum may justly be deemed a suflScient reason for its having become the seat of the only characteristic lesion in the stomachs, the normal constriction of the part rendering this mode of slough- ing or breaking down of mucous membrane, when engorged with disorganized blood, a natural and certain consequence, yet it was deemed important to search diligently in that and other portions of the gastro-intestinal lining, to discover if any parasitic or fungus organism might chance to be associated with such a peculiar kind of lesion of the membrane. None was found. But, to the patho- logical anatomist the causes of this lesion cannot appear doubtful, particularly when it has most extensively appeared in those ctises 1110 Annual Report of New York in which the structures and functions of the spleen (as the grand diverticulum for the excess of blood flowing to the stomach), are con- sidered. This class of lesions in th^ fourth stomach was so constant (though greatly varied in amount) in the whole membrane of infected bullocks examined by the Board's officers, that when pro- perly discriminated from the lesions produced by ordinary gastritis, that, as Assistant Commissioner Morris has justly remarked, " th«; ulcerations, or, rather, the peculiarities that were found in the tubu- lar portion of the rennet or fourth stomach, and at the base of the longitudinal folds in that stomach, finally appeared to be a surer guide to a recognition of the disease than was the mere appearance and size of the spleen or the liver; the absolute tests by the minute examination of the liver, bile and spleen-pulp by the microscopist, and the historical and symptomatic history of the animal before death, being, of course, preferred to all other kinds of evidence. Yet to the practiced eye, these ulcerations, sloughs and erosions served as trustworthy guides in deciding the nature of any case in which for the moment, the other kinds of evidence were not accessi- ble." The plates which are given in this report, to illustrate the gastric lesions, present a fair average of them, both in regard to extent and morbid coloration, etc. Intestinal Canal. — The lesions found in the intestinal canal were regarded as being important only as illustrating: 1st. The exist- ence of passive engorgement in the mucous membrane at various sections, principally in the coecal portion (plate 9, fig. 1), and in the rectum (plate 14, and plate 8, fig. 2). The mere congestion which was always found in various portions of the small intestine, seemed to be wholly unimportant, except so far as it showed very happily the nature and universality of the capillary engorgement that occurred in the acute or last stage of the disease. Plates 14 and 15 illustrate this condition of the intestinal mucous membrane. Constipation seemed to be the usual condition of the bowels during a number of days preceding death, in the infected cattle. The intense and deep engorgement of the rectum and the peri- rectal tissues in the sick animals, was a very noticeable fact. So, also, was the presence of bile in the intestinal tract in most cases, even in those that were great sufierers from constipation. The question will naturally be asked, but we cannot answer: "Why was there constipation when an ample quantity of bile was found in the intestinal canal?" But this fact may here be stated, viz: State Agricultural Society. 1111 that in feeding rabbits and mice upon breads and salads saturated with the bile from these infected beeves, diarrhoea was rarely pro- duced, though such feeding, for the purpose of infecting those small animals, was in some instances continued daily for more than a week. Condition of the Lungs and the Areolar Tissue. — The lungs were in all cases found in a healthy condition, or, at least, unaf- fected by the disease, except in a verj' small percentage of the cases in Avhich the infected bullock had been for many hours inca- pable of changing his posture, when hypostatic congestion of a por- tion of the lungs was noticed. The question was often asked: "How is it possible that so great a degree of disintegration of the blood produces so little congestion in the lungs?" The fact is as we here state it, and until analytical chemistry had proved that the blood in the late stages of the disease is watery and thin, it cer- tainly was difficult to comprehend the reason for what we saw. Yet the fact must be borne in mind, in regard to the type of the disease, that it is not an inflammatory malady, and is not charac- terized by fibrinous and phistic exudations in any tissue of the body. It is true, however, that in a few instances there existed a marked degree of infiltration of the areolar tissue with serum and the fluid resultants of blood dissolution; and in reference to this there is an important fact to be stated in another place. The occa- sional occurrence of interlobular emphysema was, in all instances, observed associated with and plainly dependent upon the extrica- tion of putrescent gases in the capillaries and the free areolar tissue. In one instance, every portion of the dying bullock's areolar tissues was thus inflated with gases. General oedema and anasarca were occasionally observed, and copious efiusions also, in the more chronic cases, in which either the period of incubation had been (as we ascertained) unusually protracted, or in which there were inef- fectual and lingering eflTorts at convalescence. The latter class of cases possess peculiar interest, and have proved wonderfully instructive as objects of pathological and hygienic study. Special Conditions observed in the Serous and the Mucous Mem- branes. — The endocardial or lininsr membrane of the heart was found, in certain very acute cases of the disease, to be marked by minute ecchymoses, and, in two instances, the entire endocardial surface was deeply ecchymosed. These marks of blood changes and extravasation beneath the serous linings in the heart and blood vessels, seem to be precisely similar to those often seen in cases of yellow fever. m2 Annual Report of New York The pleuritic cavity rarely contained more than an ounce or two of serum, but the abdominal cavity always contained more or less, and it usually appeared to be blood-stained. Though, with the exception of two bullocks that had suflered extensive complications resulting from extravasations into the areolar tissue pertaining to the intestines and the surrounding fat, there were no traces of inflammation of the serous, or other tissues of the peritoneal cavity, there nevertheless was usually found in that cavity a quantity of bloody serum, as just stated. This varied from a quart to more than a gallon. In numerous instances it wtis deeply tinged with brownish-yellow, like the fat. This effused fluid possessed, in some instances, the property of spontaneous coagulation in the open air. Dr. Stiles describes some curious phenomena exhibited by the fluid, and indicating that it contained some pseudo fibrine. The mucous membrane of the gastro-intestinal tract exhibited no chronic alterations in structure, except in the slowly convalescent or very chronically sick cattle, and in all those cases the lesions were limited to the abomasum (fourth stomach). The softening, the erosion, sloughing, and the blackened patches* of the mucous membrane in the abomasum, in acute cases of the disease, were plainly due to the blood changes; while on the other hand, the peculiar ulcerations and cicatrices in the tubular portion of that stomach, and occasionally at the base of the folds, indicated the fact that some of the sloughs that had occurred during the dis- ease carried away all the tissues, quite down to the muscular structure. This latter class of lesions was found mostly in such diseased auinals as were making ineflectual efforts at convalescence. Plates Nos. 3 and 21 illustrates such a case. Plate No. 22 presents the appearance seen in the first convalescent ox that was sacrificed for dissection in the reserved group of five from Mr. Alexander's herd. This animal was rapidly recovering, and had not passed " black water " for six or seven days. The morbid appearances usually observed to exist in the intes- tinal raucous membrane are shown in Plates 11 and 14. The deep ensforffement in the mucous membrane of the rectum, as seen in Plates 11 and 21, was occasionally wanting, though usually \evy marked. Indeed, the blood-stained appearance of the excremental droppings * The blackened patches and pimcta, when minutely examined, were found to he simply extravasated blood, rendered black by the gastric juice, the mucous membrane at those points being softened and broken. The occasional presence of genuine "black vomit " in this stomach (the abomasum or rennet), only illustrated this pathological alteration of blood and tissue in an extravagant degree. State Agricultural Society, 1113 was one of the means by which the presence of infected anhnals was occasionally detected by Dr. Morris and his yard inspectoi-s, so almost constantly was this symptom present in the sick cattle, before an obviously morbid condition of the animal was discover- able. In only a single instance was the muscular and areolar tissue of the rectum found deeply involved in the engorgement, or in an inflammatory process; nOr was the mucous membrane, color, or any other portion of the intestinal canal, found to be sloughed or ulce- rated. The fourth stomach (abomasum) alone exhibited this lesion. The only instance in which this kind of destruction of mucous membrane Avas not observed, was in the case represented in Plate 4. This exceptional ctise was plainly on the verge of extensive sloughing or erosion of the lining tissues of the abomasum, for it was already deeply ecchymotic. This was a very marked case from Farmer Thomas' herd, and was killed for dissection August 13th, The sketch was made by the artist instantly upon removal of the orofan from the carcass. The mucous membrane and all appearances of the mouth, pharynx, oesophagus and nostrils were normal, with the exception of a jaundiced hue that was noticed in some cases that had con- tinued many days. But in acute cases, as in that from which the stomach last mentioned was taken, the mouth and lips had a clear and somewhat injected appearance. This is shown in plate 8, fig. 1, together with a common accidental ulcer that chanced in this case to be present. 'Post Mortem Appearances of the Brain. — In three instances the condition of the brain was carefully examined, because it was pre- sumed that those particular cases might be found to have suiiered from acute menino^itis or fi'om cerebral congestion. No trace of actual inflammation was found, but there was evidence of congestion of the cerebral vessels in two of the cases. The medulla oblongata was examined in these cases, and suflicient efi'nsion was found in one instance to have produced morbid, nervous and muscular phe- nomena. Yet the observations finally led to the conclusion that all, or nearly all the delirous actions, distorted movements and postures, and the comatose conditions that characterized various cases, were attributable to the toxeemia which constitutes the essen- tial quality of the disease. The Pathological Changes found in vital Organs "\vhich are Chiefly concerned in Depuration and Conservation of the Blood. — The importance of the blood-changes was so manifest and 1114 Annual Report of New York all-pervading in the disease, that it was deemed necessary to search very carefully for whatever structural alterations the liver, the kidneys, and the spleen might exhibit in the various stages of the disease. The fact that the lungs presented no lesions has already been stated, and we may now refer to the three other vital organs upon which the conservation of the blood depends. And for the purposes of this report it will not be needful to encumber the record of mere observations with any statements concerning the normal structure or the functions of these oro^ans. And in res^ard to the • morbid histology of most minute structural changes discovered in each of these organs by means of the microscope, all the conclu- sions that can properly be published are presented in Dr. Stiles' report in the succeeding chapter. The statement we would here make will refer to the grouping and total quantity of results of the morbid alterations in these organs, so far as a reasonable judg- ment may now be expressed concerning them. The Liver. — Increase in weight and volume was a constant fact. Taking the normal standard of weight of the liver to be from eleven to fifteen pounds avoirdupois, the average degree of augmen- tation in weight was found to be equal to about thirty per cent above the normal weight. The most excessive weight was found to be thirty-three pounds, — the steer being one of medium size, estimated at a gross weight of 1,200 pounds, — one of former Thomas' herd, killed in the moribund stage four weeks after the first exposure to the Texas infection. The increase in the size of the liver kept pace with its increase of weight. This increase in size and weight in all cases consisted chiefly in the excessive engorgement of the portal blood vessels, but in the cases that had been long in progress there was such a degree of fatty and " waxy " degeneration as to add largely to the weight and still more largely to the volume of the organ. This was the case with the liver exhibited in Plate 17, which weighed upwards of twenty-three pounds, and Avas taken from a young bullock that was slaughtered in the moribund stage of the disease, and after a long continuance of it, the entire period being probabl}?- not less than forty-five days. The shape of the liver was in some instances, as in this one, distorted by rapid increase in its size. There were some instances in which a waxy condition of the liver was unattended by engorgement with blood, but in no instance was the liver found in the very " dry " condition that occurs in long protracted fatal cases of yellow fever in man, though in several instances that con- State Agricultural Society. 1115 dition was in some cle2:ree established. The later observations in autumn clearly indicated that the " waxy " * change occurred in the animals that suffered long with the disease. This was most strik- ingly illustrated in the ox that was killed for dissection the 18th of October, and some of whose morbid conditions are strikingly represented in the several figures in Plate 23. This liver weighed eighteen and a half pounds, and strongly resembled the " dry" con- dition in persons that die after twelve or fifteen days' suffering from yellow fever.f Before concluding these statements concerning the obvious and essential alterations found in the liver in this disease, it is necessary that we should remark that no special importance is attached to the ordinary and familiar modes of observation and description. The color and consistence of the liver were not in all cases so obviously changed as to attract special notice. The morbid condition of the bile, and especially, a certain quality it displayed when tested upon blood-globules, — dissolving them almost instantly, as described in the next chapter by Dr. Stiles, — rendered it very desirable to have scrutinizino; examinations made in re^^ard to the intimate or inteojral changes that might be found in the minute organization and struc- ture of the liver. The pathological alterations in an organ so elaborately organized and structurally guarded as the largest and most constantly active of all the secreting organs of the animal system, — the liver, — may suffer grave and dangerously injurious pathological changes both in structure and function, and still retain a fair appearance upon its surface. And as regards the discoveries that Dr. Stiles has made in his researches into the morbid alterations ill the liver, and incidentally, into one of the most important elements in its pathological structure, namely, the ultimate distri- bution or reticular structure of the biliary duct system, it plainly appears that no ordinary observations could ever have reached such definite results, or have added such welcome and yerj necessary facts for guides to the proper interpretation of the nature and conse- quences of the malady we are here considering; and important, too, for the more exact understanding of certain most destructive human pestilences. The morbid and morphological changes and abnormal elements •As described by the histologists, or uader microscopical observation, this alteration in structure consists in a thickening of the walls of the secreting cells of the liver. i" The chief pathological changes in this disease of cattle promise to throw so much light upon those of yellow fever that we deem it proper to call attention to such points of resemblance wherever there is an essential and characteristic alteration of structure, kc. Hi 6 Annual Report of New York discovered at the outset in the bile of the diseased cattle, served both as a guide and an incentive to patient researches and experi- mental tests. The next chapter will sufficiently explain the nature of this interesting line of investigations. Eut let it be remem- bered that the first fact that was demonstrated or asserted con- cerning the source or carrier and vehicle of the contagious cause was this, namely, that the excrement of certain Texas cattle is directly chargeable with this unfortunate evil. Hence we came to regard with interest whatever abnormal elements or properties the bile of the diseased cattle possessed, because it is a ready vehicle for carrying into the excremental droppings whatever may pertain to it. The experimental investigations in regard to the fungus organisms found in this morbid bile ' are still in progress. In this branch of inquiry we invited and obtained the cooperation of Prof. Ernst Hallier, of Jena. That gentleman is justlj' regarded as the highest living authority in experimental and analytical researches of this sort in the study and cultivation of the microscopical organ- isms that infest plants and animals. Prof. Hallier's plan of inquiry in regard to the spore organisms that are found in the blood and bile of the sick cattle will be found in a subsequent section of this report. Though this particularly abstruse line of inquiry has been only collateral to the first objects that were to be kept in view in the work, and though the actual relations of the fungus-spores in the blood and bile may not be fully grasped in the present — merely preliminary stage of inquiry — and may not throw any light upon either the source or the essential nature of the disease, at least until naturalists shall have advanced many steps further in the study and analysis of the parasitical fungi, the demands of progressive know- ledge require that whatever facts have been acquired in regard to this collateral, and, probably very essential line of studies, should not be timidly withheld from publication. Therefore the committee has advised that the record of this class of observations should be embodied in this report. And as this parasitical element of th« morbid bile has become an object of special examination, we refer to it now as one of the constant elements found in the bile of th« infected cattle. The Spleen. — The most obvious of all the morbid appearances exhibited upon the mere exposure of the abdominal viscera to exter- nal inspection is that which the spleen presents in most cases of the disease. The morbid changes that occur in the essential and intimate structure of this organ seem to be equally as constant as State Agricultural Society. 1117 those which occur in the liver, but, consideriug the comparatively subordinate fuuctions that are required of the spleen, — so far as its fuuctions are understood — its pathological changes cannot reason- ably be regarded as being so important and far-reaching in their mflueuce, as attributes of the disease, as the structural and morpho- loorical changes in the liver seem to be. But as the grand diver- ticulum or waste-gates to the portal and gastric circulation, the spleen would inevitaby become engorged and swollen to abnormal dimensions so soon as eno:orgements and obstructions in the circu- lation of blood in the liver, or the liver and the rennet stomach occurred. This is an accepted deduction in physiology, and requires no further remark in this place. Yet it is not certain that the mechanical and anatomical disturb- ance which the disease produces in the spleen does not finally induce morbid conditions in it, or, as seems probable, so cripple and overwhelm its special, but obscurely known functions, that the total suspension of those functions may contribute towards the rapid and fatal dissolution of the blood itself. The fact that the spleen is generally believed by physiologists to be charged with some special duty towards the repair of the blood corpuscles, or at least, the duty of completing the normal dissolution of the defective and worn red corpuscles,* gives peculiar interests to the pathological inquiries concerning the share the spleen has in this disease. Dr. Stiles has carefully described the degenerative and other structural changes which the microscope revealed in the cases which he examined. The very constant presence of crystals of hgematoidine in the enlarged cells of the spleen, toge'ther with the peculiar yellow flocculi, such as were found abundantly in the blood and the bile of every infected bullock must be regarded as important circumstances. ♦The difficulty hitherto experienced in all efforts to demonstrate the nature and functions of the spleen and the thymus gland, need not prevent us from adopting the conclusion that notwithstanding the morbid alterations in the structure and functions of the spleen may be secondary to those in the blood and the liver, they nevertheless can contribute important results towards the final fatal end. As that philosophical writer. Dr. John Simon, has said of the thymus gland that " it seems to serve the purpose of a sinking fund in the interest of respiration," so it may be said of the spleen, that it serves as a sort of " sinking fund " in the interest of the worn and expiring red blood-globules, and of a sound state of the circulating blood. And continuing the figure it may reasonably be presumed that the destruction of the "fund" may, in the critical exigencies of disease, contribute to the general disaster which the blood and life itself must suffer. At any rate this illu.-;tration aptly conveys, in a homely way, a correct idea. We would invite attention to the results attained by Dr. Stiles in his study of the changes, — both morbid and conservative, — that .♦ccur in the spleen in this disease. 1118 Annual Report of New York Theories regarding the relation of the spleen changes to the dis- ease or to its fatal termination, are of minor consequence, for physiologists and pathologists will not hesitate to agree with Dr. Stiles in the very reasonable opinion, that all the essential changes in this organ of the infected animals are of a secondary character. The diseased conditions which were uniformly found in the liver and in the fourth stomach, would inevitably be attended by engorge- ment of the spleen. There were four or five instances in which cattle were found dead with this disease in the Metroj)olitan market yards, or aban- doned by the wayside, and dissected at the rendering dock, in which the spleen was said to be found ruptured. The fact is, that in every such case, this organ was also found in a state of total disintegra- tion, a mass of diffluent pulp. Descriptions which have lieen forwarded to this committee of post mortem appearances of the spleen and other viscera found in diseased cattle in various places in the Western States, show that the instances are not infrequent in which the spleen is found in the condition here described, particu- larly if the infected animal lingered to die in the natural way. The sanitary authorities of Chicago, Illinois, — having ascertained through Dr. John H. Ranch, their intelligent sanitary suj)erintendent and registrar, that an increased weight and volume of the spleen were the most readily observed facts to which they could officially direct the attention of butchers and meat inspectors, at the immense slaughter-pens of that city, where Texan and Western beeves are, killed for packing as well as for the city stalls, — ordered that all spleens should be carefully and separately weighed, and that exces- sive enlargement and disorganization of this organ should be regarded as sufficient evidence for the condemnation of particular cattle and herds, so as to prevent sale and slaughter. Though an engorgement and very great enlargement of the spleen may occur from various other causes than the Texas cattle infection, this test which was adopted by Dr. Ranch for convenience sake, and fully approved by Prof. Gamgee, undoubtedly served the practical pur- pose of the sanitar}?^ authorities of Chicago exceedingly well. Dr. Rauch has politely furnished us a transcript of the entire record of the weights of spleens and livers that were inspected under his authority at the Chicago slaughter-pens. The record of the native cattle (Illinois and Missouri stock) shows that 4,918 were killed, and that the average weight of their spleens was 1.35 pounds each; while the record of the freshly arrived Texas cattle shows IState Agricultural Society. 1119 thiit 3,485 were slaughtered, and that the average weight of their spleens was 2.28 pounds. The details of these records show that the spleen in native bullocks rarely exceeded one and a half pounds, excepting in the case of those that were sufiering from Texas cattle disease; also, that in the Texan cattle recently arrived there were particular herds in which nearly one-half of the bullocks had this organ so greatly enlarged that it weighed between two and a half and four pounds, or an average of nearly three pounds. The wood cut, No. 1, on the jDreceding page, is sketched from a photograph presented to us by Dr. Ranch, of a group of healthy and unhealthy spleens. In the second sketch is shown a group, selected by Sanitary Inspector Dr. Janes, at one of our city slaugh- tering houses, the small and natural specimens being from native or State cattle, the enlarged ones being from infected Texas steers freshly arrived from Texas, by way of Illinois. The term " spleenic fever," which has been applied to this dis- ease, and the term " milzbrand " that is applied to a group of authracic fevers in Central Europe, do not convey any correct idea of the essential nature of the diseases to which they are applied, though they thus prominently mention an organ which, from pecu- liarities in its anatomical construction, readily takes on certain very obvious morbid appearances.* •The familiar and expressive terms in which some of the best medical observers of the Texas cattle disease in Missouri and Kansas have described the symptoms, and the patho- logical changes produced by it, serve to convey some important facts which will explain various apparent discrepancies that have appeared in the descriptions of post mortem appearances. The fact that the sanitary officers could make no scientific use of the putres- cent mass of viscera, which was almost invariably found upon opening an infected animal that had been dead more than an hour or two, will explain, also, how different are most of the descriptions of their post mortem dissections from those published elsewhere. For an illustration of the first-rate descriptions which have been given by some Western observers, who have been many years familiar with the disease, we quote the following extract from a report of Dr. Albert Badger, Nevada city, Vernon county, Missouri. Con- oerning post mortem appearances, he says : " In a very close observation of this disease among my own and neighbors' stock for the last thirteen years, I have generally found on opening those that had died but very little blood, and the following results : In those that passed water, mixed with blood, the kid- neys and surrounding parts were entirely decayed, the other parts of the body sound ; those that did not dung at all, or but very little, with manifolds perfectly dry and partly decayed, while the large stomach would be more or less mortified, other parts healthy; those that appeared to dung and pass water naturally, with a liver more or less decayed, the gallbladder always swelled to its greatest tension, other parts healthy; those that were ever on their feet in a watchful attitude, the brain was found more or less decayed. This leads me to believe the disease to be in the blood, which finally becomes congestive, destroying the parts in a fews hours after it becomes seated, and no doubt in many cases could be cured if we knew exactly when and where it had seated itself — blood-letting not being sufficient of itself to check the inflammation. The hollow horn and tail no doubt is caused by the fever destroying the blood in the extremities before it does in the vessels, which it does destroy in a great measure before death." 1120 Annual Report of New York It would be difficult to find, lu the whole category of human diseases, so striking an illustration of the disintegration and ulti- mate destruction of the blood, associated with so extensive and so rapidly-produced fatty degenerations of tissue in the liver, spleen and kidneys. Yellow fever and malignant congestive (intermittent) fever are respectively attended by some of these changes; but we have witnessed no disease previously, in man or the lower animals, that has afforded such an opportunity for demonstrating the mode and the various results of blood-poisoning. The wasted, crip- pled and shrunken red globules; the transudations and ecchymoses resulting from this drainage of the vital fluid; the injurious and obstructive presence of resultants of this damaged blood in the tissues of the liver; the overwhelming of the spleen by the debris of the spoiled blood; the views which the microscope revealed of the condition of this debris and of the spleenic tissues in the fatal stages of the disease, and during successful convalescence; and, lastly, in cases that lingered beyond the acute stage, the presence of crj'stalized hmmatoidine — that beautiful signet and memorial of the destroyed blood-globules and consequent transudations — in all loose tissues and the chief seceruant viscera of the body, presented, together and in their various relations, the most remarkable, the most instructive, and, when studied with all the associated facts, the most conclusive results that could be met with in the phj^si- cian's searches into the nature and consequences of a pestilential disease. It would be impossible, in a mere report of events and particular results in the committee's investigations, to place all of the more interesting and conclusive circumstances on record concerning par- ticular observations in individual cases of the infected cattle. Each case, when carefully dissected and studied, presented striking " me- morial tracings" of the morbid changes, that had occurrd in the blood. For example: An infected bullock was killed for dissec- tion, October 18th, at the National drove yards on Third and Fourth avenues. [This bullock's jaundiced skin, waxy and fatty liver, and partially restored spleen, are represented in Plate 23,] The fat surrounding the kidneys, and, to some extent, that of the omen- tum, was of a greenish and mottled appearance, and the cellular tissue contained some opaque serous fluid. The dissector cut the discolored fat with caution, saying there must be pus in it. But it was simply a mass of hasmatoidine crystals, which remained there as a signet left by the disintegrated red globules of the spoiled State Agricultural Society. 1121 blood. Ill other cases, both lingering and acute, brilliant and dis- colored spots in pelvis of the kidney were found by Dr. Stiles to consist of hsematoidine. Besides this beautiful seal, which the disease impressed upon the glandular and cellular tissues, there always could be traced other series of proofs of the nature and results of the blood changes. [Dr. Wm. Aitkin, in his remarkably instructive chapter upon " Symptoms and Signs of Disease," happily epitomizes the facts relating to the source and significance of hsematoidine crystals found in the tissues and closed cavities of the body, in the follow- ing remark: " Crystals of hgematoidine are the most frequent products of blood-degeneration (Virchow). They are formed spon- taneously out of haematine. * * * If large masses of extrava- sated blood continue to lie for any length of time, this is the substance into which the blood is transformed. An apoplectic clot in the brain, for example, is repaired by a large portion of the blood (the clot) undergoing this transformation, and the color of the resulting cicatrix is due to the crystals of hgematoidine. When a young woman menstruates, also, the cavity of the Graefian vesicle, from which the ovum escaped, becomes filled with coagulated blood, and ultimately hcematoidine crystals are the last memorials of the event (Virchow)."] Hie Kidneys — Dr. Stiles submitted specimens of this organ to microscopical examination from all the cases of which he also had opportunity to examine the liver and spleen. The changes in ■structure are in harmony with those found in the latter organs and in the blood. The kidneys indeed, contained certain very imports ant evidences and signets of the rapid destruction which the red blood-globules had undergone. Nothing could be more significant than the lodgment of crystals of hgematoidine in the tissues of this depurative gland. The average general appearance of the kidneys in the infected bullocks which we slaughtered and dissected for purposes of scientific investigations, is correctly shown in the plate on the next page. This specimen (Plate 19) and its mate (Plate 20, fig. 1) on the page following, were taken from a young bullock slaughtered at the National drove yards. One Hundredth street, September 26th. The two weighed five pounds eleven ounces. The appearance of the kidney during convalesence, at the end of seven or eight days in progress of recovery, is represented in Plate 20, fig. 2. This specimen was taken from the first con- valescent of Mr. Alexander's herd, August 16th. [Ag.] 71 1122 Annual Repobt of New York In man}^ instauces the morbid appearance was less marked than in the examples here represented; but in still more cases there was vastly more alteration in appearance, and with scarcely an excep- tion as is reported by all observers, there is usually a more morbid appearance of the kidneys than that which is here exhibited. But it is not in the mere appeai^ance, but in certain morbid changes which the microscope alone can reveal, that this organ has aided the general inquiry concerning this disease. Often, in the post mortem inspections of cattle found dead, and in slauglitered and allowed to remain a few hours, the kidneys were found utterly disorganized and almost as diffluent or broken down as the spleen in the same animals. A marvelous rapidity of disorganization and putrefaction of this and every other organ that was similarly engorged with blood, will be remembered by all observers as a decided characteristic. But it is a fact to be noted that the kidneys as well as the liver, kept up a remarkable activity of secretion, or at least of evacuation of morbid secretions, until a very late stage of the disease. The source and nature of the "black water," or hasmaturia are correctly illustrated in Dr. Stiles' report [Plate 7], and in the chemical analyses of urine and blood, by Professor Chandler. The loss of blood-albumen by the kidneys in this dis- ease is in all cases enormous, and the blood analysis shows that this loss goes on pari j)assu with the disease, so that in long pro- tracted cases it reaches a minimum percentage of the quantitative results in the table of analysis. * The report of Dr. Stiles which follows in the next chapter, ade- quately sets forth the results of microscopical examination of the three vascular organs that we have mentioned in this section, as being the chief objects of interest in those pathological researches. All other organs and tissues of the body were in turn examined, but it was in these three organs, the most vascular, the most sus- ceptible to morbid alterations in their organic and interstitial constitution, while, also, the respective functions which they seve- rally perform in preparing the blood for its continued flowing as the healthful supporter of life, that distinctly and very peculiarly characterized alterations in structure, most important, far-reaching and fatal in results in the infected cattle were observed. But the * The decrease in the percentage of albumen in the blood manifestly depends upon three eauses, viz., loss by waste through the kidneys; loss by the destructive effect of the fever in which this blood of food has to meet unusual demands; and lastly, the failure of the eick animal to supply by its digestion of daily food. State Agricultural Society. 1123 statement must here be repeated, that it is not in the fortuitous changes of color, size and apparent healthfuhiess of these organs that the question of their healthful or their diseased condition is determined in an acute malady like this of the Texas cattle disease. Devoted to special and vitally important functions of blood pre- servation, each of them containing characteristic marks of morbid conditions induced by the poison of the disease, and each in its own peculiar way, finally becoming embarrassed in function and organic structure, these organs were the subject of daily study by Dr. Stiles and various medical observers for more than three months. The results of that study have been worthy of the labor bestowed, for very important facts have been ascertained which throw light upon the nature and course of the disease that was under investigation, and at the same time contribute to the progress of important branches of medical knowledge. Note on Special Conditions Observed in Convalescent Cattle THAT w^ere Slaughtered for Dissection. — In the report by Dr. Morris will be found an abstract of notes taken at the post mortem examination of the five convalescent cattle belono-ino- to Mr. J. T. Alexander's herd. They will repay perusal. Much might be added to these notes that would be interesting to pathologists, and also would be important to farmers and herdmen that may have to deal with the disease. We will briefly recapitulate the most essential facts observed in the examination of animals known to be convalescent from the disease: IsL External Appearances. — For several days the eyes appear jaundiced, the skin also, in certain cases, was seen to be deeply jaundiced; and this is strikingly shown in the case of a bullock that was slaughtered on the 18th of October, after being at least ten days past the commencement of obvious symptoms. The appearance of this animal is correctly shown in Plate 23, fig. 1. The cases examined late in the autumn, like the one here mentioned, had oedematous legs, and exhibited a very flabby condition of surface. 2d. The Temperature. — Examined per rectum, the first of Mr. Alexander's convalescents (slaughtered August 16th) on the seventh day after last of the hiematuria, gave a temperature of 103^*^ Fah. The other members of that convalescent family, which came to their dissection for scientific purposes on the 26th of August, from twelve to sixteen days past obviously acute sj^mptoms, gave the fol- lowing temperatures: No. 1, 103°; No. 2, 103 1°; No. 3, 103 1°; No. 4, 103|°. In other instances of cattle partially i-ecovered from the 1124 Annual Report of New Yore disease, there usually was some complicating coudition that kept up the febrile temperature, as iu the bullock whose jaundiced skin is illustrated on the preceding page. His temperature, when ten days or a fortnight past the obviously acute stage, but when suffer- ing intensely from inflammation of the rectum and colon, and from the extravasation of his anasmic blood into the cellular (areolar) tissues of the body, was 105 ^'^. In several of the imperfectly recovered Texas cattle, examined by Sanitary Inspector Janes at one of the butcheries — cases quoted by Dr. Morris in this report — ■ the temperature was two degrees or more above the standard of health. 3d. Condition of the Blood. — In all the convalescents it was remarkably deficient in red globules and globuline, and in the per- centage of salts, of albumen, and of total solids. This is shown in the chemical analysis of the blood of diseased bullocks by Prof. Chandler. [See his Tabulated Analyses.] The same fact was con- firmed in the microscopical examinations by Dr. Stiles, in regard to the destruction of the red globules. 4th. Tlie Spleen and Liver. — In every convalescent these organs exhibited evident traces of the disease. The weight and the unnatural appearance of the spleen seemed to be very tardy in the return to normal conditions. The spleen of the first examined convalescent in Mr. Alexander's herd (on the seventh day) weighed five and a half pounds, and was still soft and discolored; while the liver weighed thirteen and a half pounds, and was fatty and fawn colored. In convalescents killed later in the season, the " waxy" conditions were conjoined, and the former was evidently superven- ing upon the latter condition. In Plate 23 a section of such a liver is shown, also a section of the spleen. They evince a tardy return towards the healthy state. 5th. The Abomasum or Fourth Stomach. — ^A rapid tendency to recovery from the common erosions and ecchymotie conditions in the tubular or " reed" portion of this stomach was evinced in the well conditioned convalescents; but the deep sloughs and ragged ulcera- tions recovered slowly. Plate 21 exhibits the appearance of the tubular or "reed" portion of the abomasum in the first bullock killed in Mr. Alexander's group of convalescents, at Communipaw. 6th. The Bile, the Blood, and the vascular organs concerned in blood elaboration, continued to exhibit the yellow flocculi or pig- ment matter and the hsematoidine crystals for some time. But the fungus spores ceased to be found quite early. The completeness State Agricultural Society. 1125 and rapidity of this disappearance of the fungus parasite in the cattle that were medicated with carbolic acid was, at the time, a subject of unexpected satisfaction. It was reasonably presumed to be due to the action of the carbolic antiseptic upon the blood. EXPERIMENTS TO TEST THE SUPPOSED METHODS BY WHICH THE DISEASE MAY BE COMMUNICATED. In the beginning of our inquiries the fact became so unequivocally established that to the excrement of the cattle which introduced the disease was to be attributed the means or vehicle of distribution and propagation of the infectious cause of it, that it was believed there would be a spontaneous demonstration of the possibility or the impossibility of the re-propagation of the poison by Northern cattle which were under observation and dying with the disease in the vicinity of New York. The only instances of such re-propa- gation by sick native stock are related by Assistant Commissioners Drs. Morris and Montfort concerning the herds in Orange comity. Dr. Stiles attempted some experiments by injecting a solution of infected bile into the blood vessels of some of the lower animals, but they gave no other result than that of a speedy termination in fatal convulsions, as soon as the solution mingled in the general circulation. The constant presence of the fungus-spores in the bile of the infected and dying cattle suggested the propriety of instituting a series of experiments and tests upon such herbiverous and carni- verous animals as could readily be made to partake of simple foods garnished with a little of the morbid bile. To Dr. F. J. Randall an Assistant Sanitary officer, the task of conducting the experi- ments was committed. Dr. Stiles followed up the examination of the morbid anatomy and microscopy of the fluids and diseased tissues whenever death ended the experiments upon any of these small animals. The experiment on dogs was inconclusive. Dr. Mackay, the Health officer of Buffalo, had informed us that all his observations in feeding dogs with the flesh of the infected dead cattle ended in poor Tray's vomiting the food. Three dogs were kenneled and fed very sparingly on two of the enormous livers taken from infected cattle that were slaughtered for dissection. Two of them were attacked with an obstinate diarrhoea and one of them died at the end of twelve days. The stomach of the latter was ulcerated, but Dr. Stiles discovered no traces of the essential signs of the cattle 1126 Annual Report of New York disease. It was scarcely presumed that the dog would readily succumb to the poison if any pertaiued to the tissues of the liver and the bile they contained. The facts regarding the pathological results of this feeding and incubation of the bile-poison, if poison it was, are summed up by Dr. Stiles in the second part of his report. He found all the characteristic lesions which the infection induces, and he remarks that the rabbits " died with many of the phenomena of the Texas cattle disease." Dr. Randall states that they died suddenly in every instance, after but a brief period of apparent illness. The only fungus-spores discovered in the dead rabbits were those known to mycologists as the Oryptococcus guitulatus. Eegarding the practical inference to be drawn from these experiments we would not con- sider them absolutely conclusive, because the absorption of morbid bile into the blood would in all probability produce the chief results that were observed by Dr. Stiles and Dr. Eandall. Yet, so far as this series of results has any bearing upon the theory of this fever-propagation, by means of this germ-element, they are regarded by Dr. Stiles as strongly conlirmatory. Experimental tests showing the eifects that would be produced by the transfusion of blood from an infected bullock into a healthy one was scarcely practicable, as every medical observer was already overworked, and no pecuniary means were available for such experi- mentation. That class of tests remains to be made, together with several other experimental observations if the infection ever again crosses the Mississippi river. INDISPENSABLE USES OP THE MICROSCOPE AND CHEMICAL ANALYSIS IN THE INVESTIGATION.— RESULTS. The microscope and the chemist's laboratory are helps to the stu- dent of the causes and effects of disease, but they may as readily prove false guides as true, unless they are themselves directed by skillful and thoroughly experienced hands. The success that attended the labors of Dr. Stiles and Prof. Chandler, in their res- pective branches of investigation, will justly be regarded as among the most satisfactory results attained in the whole range of inquiry. The reports of those two co-laborers follow in next chapters. Divested of the technicalities of such studies, their results may be concisely translated into familiar phraseology, as follows: What the Microscope has revealed concerning the Pathological Characteristics of the Cattle Disease. — (1.) That the red corpuscles State Agricultural Society. 1127 'of the iufected blood are impaired, and, to a great extent, broken up before the death of the iufected animal; and that, immediately after death, the disintegration of this essential and life-bearing con- stituent of the blood, as well as the other constituents, went on with amazing rapidity. (2.) The chief change discovered in the liver, spleen and kid- neys, consisted in the acute fatty degeneration or deposit, and in certain remarkable evidences of embarrassment in the circulation of the blood and of destructive changes in it. The presence of the crystals of hasmatoidine, and of a peculiar yellow matter, in these organs and in the bile, as well as in loose cellular tissue, were so remarkably demonstrated under the microscope, that they came to be regarded as signets of the presence and operation of the disease upon the red blood-corpuscles. The yellow matter here mentioned also associated destruction of the red corpuscles with the presence of the morbid bile; and this circumstance, in the pathological con- dition of the blood, was rendered quite certain by other kinds of evidence. (3.) The diseased distension of the minutest biliary ducts by the morbid bile, revealed a physiological fact regarding the minutest and previously undetermined character of the ultimate arrangement of those ducts and their relations to the secreting cells of the liver. This discovery by Dr. Stiles has served to aid in the investigations and deductions. (4.) The exact nature and causes of the " black water "^ or hsema- turia have been clearly defined by the microscope. (5.) The nature of the morbid changes which occur in the spleen in consequence of the disease is clearly defined, so far as the micro- scope can reveal the altered conditions in that organ. (6.) The presence of fungus-spores or an infinite growth of parasitical organisms, has been revealed as a constant fact in the blood and bile of the infected animals. And to test and develop, by experimental culture, the actual nature and botanical (niyco- logical) classification of this fungus parasite, has been a separate undertaking. Furthermore, without waiting the results of such culture, the microscopical observations upon the bile, the minute tissues of the liver, and the morbid conditions of the blood, &c.,. are finally regarded as warranting the conclusion, that whether it may be an active and propagating el,ement in the Infectious cause of the disease, or only a concomitant of the diseased and feverish blood in the infected animals, it certainly seems to play an important 1128 Annual Report of New York and fatal part in the final morbid changes that occur in the bile, if the bile becomes, as there is no doubt it does at last, a destructive poison to the blood and the nervous centres. (7.) The microscope has enabled Dr. Stiles, and Prof. Hallier (of the University of Jena), to trace the botanical and developmental history of the fungus element or " micrococcus." In these, and in various other ways the pathological investigation.^ of the disease has been aided by the microscope in the hands of a most leai'ned, careful and trustworthy physiologist and pathologist. RESULTS FROM CHEMICAL ANALYSIS. The Blood. — In the eight columns that present the results of the quantitative analysis of blood from fourteen infected bullocks that were slaughtered and carefully dissected for the purposes of our investigations. Prof. Chandler has clearly demonstrated the fol- lowing facts: (1.) The normal relative proportions of the total solid constituents, and the water of the blood in the infected cattle, was found to be changed, the healthful percentage of solids being much diminished, and in the most typical cases of the disease this decrease of solid constituents was excessive. In a fine fat steer that had passed the acute or explosive symptoms, and was (ineffectually) convalescent, this decrease of solids in the blood was found to be equal to fifty parts in the 1,000 of blood, or of the one hundred and ninety of normal solids, that is, this loss exceeded twenty-five per centum of the natural total of solid flesh-forming constituents in the blood. In other instances in which the disease produced extreme symptoms in very fine and full fleshed animals, as in one that was carried to the rendering dock, and in two that were killed and carefully dis- sected September 11th and October 18th, respectively, the loss of solid elements of the blood was found to be nearly seventy parts out of the normal proportion (which is about one hundred and ninety) in the 1,000 parts of blood, or equal to thirty-seven per centum of loss of the substance of the blood. But the loss of solid elements was not an invariable fact, though evidently quite sure to occur ill extreme cases, and in all instances of lingering beyond a few days after the period of hematuria and the acute symptoms. (2.) In every case of the disease there was a very marhed loss of red blood-corjpiLscles. The loss amounted to more than fifty per cent of the total quantity that healthy bullocks' blood contains; and, in the most striking cases, the loss of blood corpuscles and State Agricultural Society. 1129 globuliiie was almost complete. In some examples (one of which Prof. Chandler has placed in his tabulated results) the destruction of this most essential element of the blood could not be estimated, so entire was the destruction and change. (3.) The healthful proportion of salts in the blood was dimin- ished in all the typical cases that had snrvived a few days after the onset of acute symptoms. The causes of this loss, as well as that of total solids were physiologically obvious in the class of animals in which it occurred. (4.) Albumen was quite constantly found below the healthful proportion in most of the cases examined, but it was noticed as in excess of the normal amount in those cases of the disease in which the blood-corpuscles and globuline had undergone such changes as caused the red globule element to nearly or wholly disappear from the list of proximate elements. (5.) The fibrin varied greatly in amount, but in the phenomena of coagulation, &c., never exhibited signs of an inflammatory condition. In some instances the fibrin appeared rotten and imperfectly elabo- rated; but in no specimen examined under the microscope did Dr. Stiles notice any unnatural state of fibrillation. The foregoing five points of departure from the healthful standard of the blood elements are thus specially noticed, because they are very directly associated with the essential cause and course of dis- ease. The Dropsical Effusions {Serum) in the Peritoneal Cavity of the Infected Cattle. — The eflused dropsical fluid possessed the pro- perty of spontaneous coagulation when exposed to the air. Dr. Stiles' description of the peculiar mode of that coagulation shows that a pseudo fibrin was contained in these fluids. Prof. Chandler's analyses show that this fibrin was quantitatively estimated. In the remarkable case that was examined the 9th of September, the spleen was ruptured, accidentally, as we believed at the time, in last struggles, or in the handling of the bullock. [See third analysis of serum and eighth analysis of blood, in Prof. Chandler's tabulations.] Chemical Analysis of the Bile. — The results are recorded with- out comment. There* may be readers of this report who would ask for these results, and the time may come when this class of facts will aid in other inquiries. The Urine. — The albuminous state of the urine was in all cases remarked, and in most instances this wasting of the substance of 1130 Annual Report OF New York blood by the urinary organs was excessive. The morbid changes that were occurring in the blood itself — by damage to the red globules and to the fibrin — would account for this wastins;, even if the kidneys had not been found to be undergoing acute degenera- tive changes, and suffering enormous congestion. And it is worthy of notice that the congestion of the kidneys (usually excessive, but in some cases annoticeable,) did not result in obstruction and sup- pression of urine, but usually in an excessive flow of it. Chemical Analysis of the Liver. — It was not until cold weather arrived that any analysis of this organ was attempted. The speci- mens were not as excessively fatty as livers dissected earlier in the season. They were changing into what is termed the "waxy" condition, in which the minute cell-walls are simply thickened by plastic matter, and, as before remarked, there was far less fatty deposit than in the livers that were not " waxy." Dr. Stiles states that the microscopical examination of the livers thus anal^^zed, contained less than half the proportion of free fat than those that were examined earlier in the season and in the acute cases. But even the four examples presented in Prof. Chandler's analyses, show an excessive percentage of fat. Here we see no less than sixty-two and a half, sixty-six, eighty-eight and a half and ninety parts, by weight, of fat in 1,000 parts of the liver substance, in livers that had, in the lingering stages of the disease, changed to the " waxy" condition. Frerich found only twenty-two parts of fat to 1,000 of substance in a wax}'^ liver, and one hundred, and seventy-two parts in a fatal case of "fatty liver." In pursuing a pathological inquiry upon yellow fever in man, the writer submitted a specimen of a liver from a sea captain that died of that disease, to Prof. Chandler for analysis. The man had died on about the twentieth day from the beginning of incubation of the disease at the port (Vera Cruz) whence he sailed. The liver was the most perfect specimen of the cafe au lait or dry and fawn colored condition of that organ as witnessed in lingering cases of that malady. The following is the result of the analysis: Water, 739.84; total solids, 260.16; fat, 96.31. Dr. Stiles' microscopical analysis of a specimen of the same human liver, pronounced it atypical example, of yellow fever liver, as had also the writer's professional examination of the body and history of the patient the previous day enabled him to do. It seems desirable to place these facts on record here, though they relate to a pestilence in the human family. State Agricultural Society. 1131 EXPEREVIENTS AND TeSTS FOR THE VERIFICATION AND SETTLEMENT OF Questions that have Arisen in the Course of the Investiga- tions. — The chief experiments of this kind relate to the attempts to cultivate the fungus spores that infest the blood and bile of the infected cattle. Though these experiments, and certain collateral inquiries relating to the sources whence they may have been derived, are still in progress, and may be continued a year or more, the chief object of such culture-experiments should be stated here. The design of the effort is not so abstruse as may be supposed. Divested of details, and of the marvelous things that are associated with the several stages of development in the parasite fungi, the object and the art of spore and parasite culture may be stated in ordinary phraseology as follows: The spores or vegetative germ matter found in the blood and bile of the infected cattle, present, in the fresh specimens, certain peculiarities that are sufficiently definite to enable skillful micro- scopists to recognize them with considerable certaint3^ We pre- sented to Prof. Hallier, of Jena, sealed specimens of fresh bile fi'om infected cattle, without intimating to him what results Dr. Stiles had obtained, and his description of what he saw exactly accords with what Dr. Stiles and his associates witnessed. This spore-growth in the fluids of infected cattle is, so far as Dr. Stiles was able to ascertain, invariably of the low or primordial kind of mere multiplication and growth, which is the germ-mass or micro- coccus of Prof. Hallier. Growing and repropagating, away from all direct exposure to the atmosphere, this kind of spore is termed anoeropliytic^ or growing without air. This circumstance of anasro- phytic multiplication and rapid growth is not singular, for the didium lactis, or fungus of milk — also an^rophytic — illustrates this kind of vegetation; but it is manifest that the circumstances of such parasitic growths must necessarily occur wholly at the expense of the constituents of the fluid in which they float and mul- tiply, for they grow without the aid of atmospheric air. As the spore-forms( or as the micrococcus^ cryptococcus, zooglom^ or cylin- drotmnum forms,) of fungus organisms all have relations to the higher and more complex development of plant-like fungi and algas, the planting and cultivation of the micrococcus or spore-matter has become an art that promises important results. The very first con- tributions of the practically useful results of that art were given to hygiene. We refer to the study and development of the fungus- forms that pertain to the excrement of the cholera sick. And as 1132 Annual Report of New York the world is indebted to Prof. Hallier, of the University of Jena, for the chief discoveries and improvements that have been made in this difficult art of studying the progressive stages of cryptogamic development from the spore-matter or micrococcus up to the plant- like stages of growth, we secured the cooperation of that learned naturalist with Dr. Stiles. He has presented his researches upon specimens of fresh bile that we sent to him under seal. The statement of results in this fungus-culture by Prof. Hallier, will be seen in the communication from him, which we append to Dr. Stiles' report in the next chapter. There is much reason to believe that this spore-growth, which both gentlemen are studying, will be found to belong to certain parasite fungi that infest the coarse herbage which covers certain tracts of country over which the Texas cattle are driven before reaching the Osage, the Red, or the Mississippi rivers. Some of the grasses of that region are already under examination by Dr. Stiles and others. No final results can be reached immediately in such an inquiry, but the clear and definite progress already made in this line of researches is sure not to end in barren uncertainties. Yet it must not be supposed that a correct general knowledge of the "Texas cattle disease" will not be attained independently of this promised contribution from the natural history of the fungus- spores of the infected blood and bile of the cattle and of the para- sites which infest the herbage of the cattle trail. These toilsome researches may result in unveiling one of hidden and all-important factors of a class of epizootic and epidemic pestilences that hitherto have defied all attempts to interpret their mysterious origin, and to discover the nature of the virus or germs by which they are propa- gated as spreading pestilences. In the present state of medical knowledge, we can only desig- nate this probable fungus or parasite element in the cattle disease as Q. factor in the sum of causes.* It may be the essential and most * "In the great field of the epidemic and contagious disorders by which the animals that minister to man are afflicted, a rich harvest yet remains to be gathered. * » * ***** A searching investigation into them would open up analogies that could not fail to be of the deepest interest in their bearing on the great group of iindred maladies which are so fatal to man. It is not too much to say that many a vexed problem relating to these last would here find a ready solution. It is, in fact, only by thus extending the survey that it is possible to obtain a just and comprehensive view of the nature and mode of propagation of that great and remarkable brood pf morbific agents which are the material cause of contagious diseases, and which, low as they are in the order of created things — as yet undefined in nature, but snecific in essence — are so destruc- tive to men and animals alike. * * * * . * * State Agricultural Society. _ 1133 important factor, or it may be subordinate td some others; but it now seems probable that the transportation and spreading of the disease by the Texas cattle, would be impossible, if this parasitical element or factor were absent or were controlled. It is not unreasonable to presume that the presence and destructive, as Avell as irritant effects of this fungus parasite in the blood and the liver, would almost necessarily induce the very changes and fatal condi- 'tions which are actually found in the cattle that die of this disease. But science and the art of sanitary prevention of disease will lose nothing by accepting all the facts and possibilities on this subject, in the same cautious and exacting way in which we have ventured to mention it in this report. That the effort to discover the precise nature and source of the infective carrier of the pestilences which are spread by means of excrement, as in the case of cholera, typhoid fever and this disease of cattle^ will, ere long, be successful, and will lead to the extinction or effectual prevention of them, is regarded probable. And there is reason to believe that this disease of cattle will yet furnish a clear demonstration in this line of study into the causation and spreading of this and some other j)estilences. " By ttis and other means so employed, we might, in no long time, succeed in investing our knowledge of whole provinces of disease with much of that precision which is the charm of the physical sciences, and medicine's greatest want. By the same means, we should gradually be accumulating data whereby to make the work of prevention sure, and thus help towards that great consummation to which we may even now confidently look — the ultimate deliverance of man from that vast brood of contagious diseases which afc present seem to mock his power — whose very existence is a humiliation to him, and which, under the form of slighter visitations or of wide spread pestilence, bring every year so many millions to the grave by a cruel and untimely death. — On the Occurrence, of the Malignant Pustule in Man, by William Budd, AI. D., London, 1863. 1134 Annual Report of New York Y. REPORT ON THE PATHOLOGY OF THE TEXAS CATTLE DISEASE. BY R. CRESS ON STILES, 3L D. To Elisha Harris, M. D.: Sir — The following contributions to the pathology of the disease which has recently proved so fatal to the cattle forwarded from the West to the New York market, are based upon microscopical exami- nation of the diseased organs collected at various abattoirs in the vici- nity, and upon experiments upon the nature of the morbid secretions. The uniformity of the elementary alterations of structure, amid a variety of diseased appearances in both solids and fluids, was one of the most interesting and satisfactory features of the epidemic. It establishes the existence of a well-defined group of symptoms and of corresponding pathological changes of structure which it is of the highest importance, both practical and scientific, to record accurately and publish widely. With the etiology, symptomatolog}', therapeutics and prophy- laxis of the disease, this report has no concern. On several occasions I was present at the post mortem examination of diseased cattle, and collected such specimens as I required for study, but by far the greater number were forwarded to me by yourself, or by your friends in Chicago and the West, where the disease has prevailed to a far greater extent than in our neighborhood. From whatever source derived, the same story was told by all; the epidemic which has destroyed thousands of cattle in the West, was identical with that from which the Board of Health has sought to protect our markets for the past three months. State Aqbicultubal Society. 1135 PART FIRST. I. THE FLUIDS. (1.) The Blood. — The blood examined, was usually drawn from the aorta or carotid arteries at the time these were severed in slaughtering the animal. In other specimens it was taken from the jugular vein during life, or from the portal vein after death. In none but the last was there any marked peculiarity by which it was distinguished from the foregoing. It coagulated firmly in a large and deep vessel within fifteen minutes, without a bufiy coat. In no case did the quality of the fibrin seem impaired. It presented invariably a delicate fibrillation when in shreds, and a finely granular appearance when in mass. The red blood-cor- puscles when examined immediately after removal from the body, were shriveled and ci'enated, without artificial provocation, as rep- resented at b b, Plate 1. In one case, many of the discs appeared to have lost a portion of their substance, as if a circular piece had been punched out, the addition of water failing to restore the disc to completeness. In one specimen only, the white blood-corpuscles were in great excess and aggregated in masses. The liquor san- guinis was invariably of a yellower color than natural, and contained minute yellow flocculi or flakes of granular matter of irregular size and shape, as represented at c, c, Plate No. 1. After a clot had formed, the serum was found to present a yellow tinge, due to a difiused coloration. The source of the yellow coloration was indicated by the occasional presence in the serum, after standing for several hours, of rhomboidal-notched plates, such as were found also in the bile, and consisted probably, of cholesterine. In sev- eral instances, defibrinated blood, or serum poured from a clot, which originally abounded in corpuscles, was found after a few hours to be absolutely devoid of the latter, complete dissolution of the red discs having taken place long before putrefaction. The specimen of portal blood abounded in white blood-corpuscles, and in morbid cellular elements from the parenchyma of the spleen. (2.) The Bile. — The bile was, in all the cases which fell under my observation, abundant, distending the gall bladder to its utmost capacity, filling the hepatic duct, and constituting the principal portion of the contents of the small intestines. Instead of present- 1136 Annual Report of New Tobk ing the normal greenish or brownish transparency, it was opaque, thick and grumoiis, nor was its opacity lost on filtration. It con- tained granular flakes and masses of a brilliant yellow or orange tint to transmitted light, reddish brown on the filter by reflected light, as represented at a a, Plate 2. These were in many cases so abundant as to give the bile a semi-solid consistence. They pre- sented, when the bile was most dense, a crimson coloration, and were then mingled with granules and stellate crystals of hsematoi- dine (Virchow), c c, Plate 2. These yellow flocculi abounded in the hepatic duct and its branches, and were found at times impacted so that they might have oflered resistance to the flow of the bile into the gall bladder. Some of the yellow coagula had been molded by the smaller biliary ducts into cylindrical casts, b, Plate 2, and were found presenting this shape in the gall bladder. Plate No. 2 represents the appearance of a drop of bile under a magnifying power of five hundred diameters. It was evident that the source of the yellow flocculi in the bile was an admixture of blood with the bile in the minutest ducts within the substance of the liver. The blood-corpuscles being dissolved, the coagulating fibrin imbibed the bright yellow dye of the mingled coloring; matters of the bile and the red bloocl-cor- puscles. I have preserved specimens of this morbid secretion for nearly three months. They manifest no tendency to decomposition, but give off a sweetish aromatic odor; crystals of oxalate of lime have formed in the yellow flocculi, and micrococcus germs have multi- plied so as to form masses visible to the unassisted eye. (3.) The Liquid Contents of the Small Intestine abounded in the yellow flocculi of the bile. The hardened faecal masses in the large intestine consisted of homogeneous yellow granules (the result of condensation of the yellow flocculi), mingled with epithe- lium and vegetable debris. Constipation was a prominent symptom in most cases. Of the bile, therefore, which was so abundantly poured into the alimentary canal, but a small quantity left the body in fiscal evacuation. The fourth stomach and intestines were occasionally filled with coagula of blood. Specimens of ooagula were sent me, but I did not witness a case of the kind. 4. The Urine. — The urine was opaque, and blaclv, with a crimson reflection. It formed a solid coagulum on boiling. When much ^diluted with water it became of a claret color. Blood-discs were State Agricultural Society. 1137 i-arely found in it, but coagula of granular fibrin, a a, plate 3, enclosing debris of blood corpuscles and dark crimson granules, and molded into ca^ts of the tvbuli urirdfen^ were of frequent occur- rence. The dark red coloring matter of the broken-down blood discs was difiused through the urine. (5.) The Peritoneal Qavity contained a yellow liquid which owed its tint to a diifused coloration, and was spontaneously coagu- lable on exposure to the air. In one case, where a few drops of blood had been accidentally mingled with it, coagulation continued for two days, and until putrefaction commenced. A fresh gelati- nous clot formed in the liquid as often as it was poured from the coagulum previously formed. This was but one among many interesting physiological phenomena revealed by study of this disease. II. THE SOLIDS. (1.) The Liver. — The liver was invariably enlarged and con- gested, its surface marked by yellow patches, or of an uniforn*' yellowish discoloration. The surface of section presented yellow spots on a ground of deep congestion. Under a low magnifying power, a thin section presented the appearance represented in plate No. 4. A translucent center of bright yellow was seen in each acinus, «, plate 4, surrounded by an opaque zone, 5, plate 4, of mingled fatty degeneration and 3^ellovv injection. Surrounding each acinus was the fibrous striation of the capsule of Glisson, c, plate 4. Under a power of five hundred diameters, the yellow color of the center of each lobule was seen to be due to the reple- tion of the ultimate biliary radicles, forming a regular net- work between the liver cells, with bright yellow secretion, a, plate 5. About this, and shading into it, was a zone of fatty degeneration, which affected the superficial or portal portion of each lobule. This fatty degeneration was sufficiently marked to render the liver cells opaque, but the nucleus was still visible in many of them. The injection of the reticulum of bile ducts was the most interest^ ing phenomenon presented by the disease, not only on account of the opportunity it afforded of studying an anatomical structure, which has given rise to much discussion among histologists, and concerning which great difference of opinion still exists, and on account of the beauty and perfection of the anatomical demonstra- tion, but owing to the important relation which this phenomenon bore to numerous manifestations of the disease. The cause of the difficulty in determining the mode of origin of the bile ducts, was I'Ag.] 72 1138 Annual Report of New York seen to consist in their fragility and intimate association with the liver cells, each cell on being separated from its neighbors carrying with it its portion of biliary reticulum. The delicacy of the mem- brane forming the walls of the reticulum, renders its thorough injection impracticable, and its recognition, when empty, impossible. The brilliant tenacious secretion of the liver in this disease distends and reveals every portion of the biliary channels. The larger ducts between the acini can be recognized in every carefully pre- pared section communicating with the intra - lobular reticulum. Immediately after death, the yellow secretion begins to pass out of the reticulum by exosmose, and to tinge the liver cells with a ditfiised yellow coloration, so that it is difficult to preserve the biliary reticulum for anatomical demonstration. Plate 6 represents the liver cells examined several hours after death. In other speci- mens the injection is more permanent, and I have been enabled to save for demonstration portions of diseased liver which still reveal ■ the most marked phenomenon of the disease. The source of the bright yellow coloration of the bile was evi- dently in the hsematoidine (Virchow) of the broken down blood- discs. The coagulating fibrin of the eflEused blood, absorbing this yellow dye, formed the characteristic flocculi of the bile; the same absorbed by the capillaries of the liver gave rise to the yellow flakes circulating with the blood, and found abundantly in the spleen. The mucous membrane of the hepatic duct was always of a bright crimson hue. In one instance, in which the injection of the reticulum of bile- ducts was most marked and most permanent, there was no fatty degeneration of the enlarged liver, but a waxy appearance. (2.) The Kidneys. — The kidneys, in every post mortem that I witnessed, were enlarged, deeply congested, black on the surface and in section, the cut surface giving issue to an abundance of dark blood. The natural distinction of color between cortical and tubular portion was eflfaced. The tubuli uriniferi of both the cortical and tubu- lar portion were rendered opaque by a deposit of granules of fat in their epithelium, and their cavity was occupied, for the most part, by coagula, reddened or blackened by d6bris of blood-corpuscles, and by granules of dark crimson pigment, with occasionally a recognizable blood-disc. Plate No. 7 represents the appearance of the tubuli of the kidney, as affected by the disease. The Malpighian bodies were not affected, but blood was occasionally found effused within their capsule. The tubular presented the same alterations as the State Agricultural Society. 1139 cortical portion. In one instance, in which the projecting cones of the tubular portion presented to the unassisted eye a glittering yellow coloration, it was due to rhomboidal plates and stellate crystals of heematoidine. Minute yellow oily drops were occasionally found scattered through the epithelial lining of the tubes. An interesting alteration in the effused blood was noted in cases of long duration, and during convalescence. The red pigment within the tubuli was changed into melanine, and black pigment- granules filled the epithelium of the tubuli. The transformation of h^ematoidine into melanine was beyond question. Long after every other morbid character had given place to healthy structure through convalescence, the cortical portion of the kidneys retained the black coloration due to granules of melanine. (3.) The Sj^leen. — Increased size and weight of the spleen was an invariable accompaniment of the disease. At the same time the consistence was diminished to such a degree that it gave issue to a soft black pulp on section, in which all trace of structural arrangement was lost. The increased size of the spleen was not due to congestion merely. A remarkable alteration was presented by the nuclear and cellular elements of the parenchyma. The nuclei (nuclear epithelium, Robin), or the same with delicate cellu- lar investmetit, which in the natural state, fill the closed vesicles of the Malpighian bodies and the trabecular interspaces, were replaced by the large cells undergoing fatty degeneration, which have been represented in plate 8. In some instances, yellow flocculi were found free in the splenic pulp; in others, cells filled with black pigment-granules and crystals of h^ematoidine were abundant. The appearance presented in plate 9 always accompanied convalesence. The cellular elements rapidly regained their normal character, but the pulp was filled with minute homogeneous rounded yellow granules, or with spherical or oval aggregations of the same. (4.) The mucous membranes of the fourth stomach and intes- tines, and of the urinary and gall bladders presented a diffused redness, with minute petechial spots, in which coagulated blood was found filling the distended capillaries. The epithelia of these membranes presented no marked alteration. The various states of congestion and ulceration in the alimentary canal offered no reve- lations of interest to microscopical study. (5.) The muscular system presented a darker coloration than in healthy animals, but under the microscope revealed no alteration in structure. 1140 Annual Report of New York (6.) The nervous system was entirely free from discoloration or structural change. (7.) The adipose and areolar tissues were tinged by a diffused yellow coloration. Occasional yellow flakes were found in them, and about the kidney, circumscribed extravasations of blood. Beautiful crystals of hsematoidine were found in old extravasations. (8.) The lungs were remarkably free from acute disease. PART SECOND. CONCLUSIONS IN REGARD TO THE PATHOLOGICAL NATURE OF THE DISEASE. To sum up the results of microscopical investigation, and give the pathological conclusions to which they point, the Texas cattle disease is an acute, infectious, febrile disorder, attended by morbid action of the liver, its most distinctive phenomena being explicable as the results of the hepatic affection. The dissolution of the coloring matter of the blood-corpuscles in the liquor sanguinis, and the hsematuria are consequent upon the entrance of bile into the bloodvessels, in whatever manner efi'ected. In the experiments of Kiihne and Frerichs, the injection of bile or of its salts, into the blood, was followed in the great majority of their experiments, upon the lower animals, by the appearance of blood in the urine. The solvent action of the bile upon the blood-corpuscles, and the consequent liberation of their coloring matter can be readily wit- nessed under the microscope, each disk disappearing suddenly, like a light blown out, and the liquid assuming an orange tint. The blood thus altered in character, becomes liable to extravasation, other haemorrhages than hsematuria being frequent attendants upon attacks of jaundice. That bile is mingled with the blood, is proved by the yellow color of the serum, its yellow flocculi, its crystals of cholesterine, by the yellow drops in the epithelium of the tubuli uriniferi, by the yellow granules in the spleen and by the hsematuria. These results cannot follow the mere accumulation in the blood of the constituent elements of bilej the proximate principles of the bile State Agricultubal Society. 1141 itself are there found. The liver is excited to excessive secretion, the product of which distends to excess the channels and reservoirs of the bile, and fills the intestines. It is not unusual to find cases of Icterus in man thus accompanied by excessive biliary secretion. That the greatest facility exists for admixture of bile with the blood, is shown by the repletion of the reticulum of bile ducts in immediate contact with the capillaries of the liver, as well as by the abundance of bile exposed to absorption by the mucous mem- brane of the intestines. In the experiments of Dr. Randall, under your direction, in which rabbits were fed upon bread soaked in the bile of the Texas disease, death ensued in from one to four weeks, according to the amount of bile consumed. In these experiments the poison was absorbed by the mucous membrane of the alimen- tary canal. The stomach was found ulcerated and containing extra- vasated blood, the liver was softened and fatty, the bile was of a bright claret color, and contained coagula; the kidneys were deeply congested; thus death Avas caused by the absorption of bile, with many of the phenomena of the Texas disease in a chronic form. The only alternative to this admission of the vitiation of the blood by bile, is the hypothesis that the destruction of the blood- corpuscles through another agent — that of the infection, for exam- ple — permits an accumulation of hsematoidine, or of the coloring matter of the bile in the blood, beyond the capacity of the liver to remove it. The yellow flocculi of the liquor sanguinis, and the spleen, would, however, be inexplicable on this hypothesis, while their formation through the agency of the liver is manifest. Quite early in this investigation my attention was attracted to the existence in the diseased bile of minute vegetable germs, which multiplied abundantly in the various specimens of bile preserved for analysis. They existed in the form of spherical or irregular aggregations of micrococcus (fig. 1, plate 10), the nature of which could be determined only by the employment of the highest powei-s of the microscope, and by studying their development. They were found in fresh blood and bile, but with difficulty. In specimens of bile collected in the evening, they would be found abundantly in the morning; the white color of their aggregations contrasting with the yellow hue of the flocculi of the bile to which they were attached, and from which they seemed to be derived, their abund- ance being such as to preclude the idea of their derivation from any other source than the blood, or the bile itself. A magnifying power of over one thousand diameters and a lens of good penetrat- 1142 Annual Report of New York iug power were necessary to their definition. Within a few hours of removal from the body, numerous cryptococcus (or torula) cells, resulting from the development of the former, were found, often containing crimson granules, as represented in fig. 6, Plate 10. Spe- cimens of bile and blood were collected from healthy animals, and carefully examined, but in no instance did the forms described make their appearance. The ordinary attendants on putrefaction were alone descried. Whether these forms of micrococcus and cryptococcus were merely accidental and attendant on a process of fermentation taking place in the bile, or were peculiar to the dis- ease, their presence was an interesting fact, and their nature deserv- ing of careful investigation. Their development was accordingly studied under various conditions. They were planted in solutions of sugar, gum and saliva, which had been boiled in order to destroy whatever germs of a difi'erent nature the solutions might contain, and were kept hermetically sealed at a temperature of 100° Fahrenheit, for several days. The resulting anaerophytic forms (cryptococcus and torula, fig. 4, Plate 10) were planted on slices of apple, etc., and their development was noted, as represented in Plate 10. After a period of two weelis the planted area was found covered with penicillium, as represented in plate No. 12, while the rest of the surface was free from vegetable growth. At the same time cryptococcus guttulatus, from the intestine of a rabbit which had been fed on the morbid bile, was also planted on slices of apple, and the germination, represented in Plate No. 11, noted. This was done for the purpose of comparison merely, cryptococcus guttulatus being constantly found in the rabbit. The cryptococcus from the bile, howevef, manifested very different phenomena, although under precisely similar conditions with the former. After two weeks it had merely increased in quantity, aggregations of spores having been foimed visible to the naked eye, but no fila- ments. These forms of micrococcus and cryptococcus are but grades in the life of higher organisms. Thus, Hallier gives the following forms or " morphen " of Achyla Prolifera: Ripe, form . . Mould jinaerophytic Schizosporangium jierophytic Tilletia caries Oidium lactis Sporidesmium Mucor racemosus Cladosporium C Penicillium I crustaceum I have taken warning from the numerous disappointments of microscopists, whose spores and germs of diseases have sprouted State Agricultural Society. 114S luxuriantly for a while in popular reputation, but have had a mush- room duration only in the annals of science. I am aware that the micrococcus and torula forms of fungi, alike in all, give no evidence of their nature and origin, and that all that can be said respecting those I have had under observation is, that it is possible that these germs, developing luxuriantly in the bile and voided with the faeces, may be the source of the contagion which proves so fatal in the Western pastures where Texas cattle have occupied them in advance of native herds. Whatever may be the bearing of these researches upon the etiology of the disease, they have an abstract interest and value independently of their practical application. The fungus origin of zymotic diseases is now conceded by the highest authorities in mycological research, and the Texas fever is one which points with unusual clearness to this mode of propagation. That Texas cattle should communicate the disease while in a state of apparent health, and that Northern cattle dying from the viru- lence of the infection should be, as a rule, incapable of communi- cating it, can be readily understood on the hypothesis that a definite stage or amount of development is required by the organic germs of the contagion before they became capable of giving ofi" the infec- tious spores by which it is propagated. The history of yellow fever shows how complete may be the immunity acquired by acclimation against a virulent form of contagion, and if the disease we have been studying were denominated " bovine yellow fever," no fault could be found with the designation. It is now admitted that per- sons in apparent health may convey the germs of cholera Asiatica from an infected district, their excreta undergoing a kind of fer- mentation through the multiplication of fungus germs, rendering them highly infectious. According to recent researches, the different stages in the develop- ment of the same fungus possess very different properties and react very differently upon the human system. Thus the best authorities assert that achorion schcenleini, which is known to be the cause of herpes circinatus and of favus, as I have proved also by my own experiments, is but an oidium form of the same plant, which gives origin to penicillium crustaceuin. If so, what limit can be set to the morbid capabilities of the commonest species of fungus? Their capacity for mischief must be as varied as the conditions of their development. So pliable are these low forms of vegetable life, that their injurious influence upon the human system, and upon the animal organism, need not be sought in their specific character, 1144 Annual Report of New York but may be ascribed to a virulence acquired by the circumstances, conditions, direction and degree of their development. This fact has received ample illustration by the researches of Prof. Hallier upon the fungi attendant upon the exanthemata. In the hottest period of summer, when the liver is excited to unusual activity, cases presenting many of the features of the Texas disease in cattle are not infrequent in man. They present the saifie fatty degeneration and boxwood discoloration of the liver, the haemorrhages into the stomach and intestines, albuminuria and fatty degeneration of the kidneys, intense jaundice, yellow grumous, but usually scanty biliary secretion, high fever, softening of the spleen; all these characteristics without the suspicion of yellow fever infec- tion. In some of these cases disorder of the liver is the only recognizable cause of a train of symptoms ending in black vomit and death; in others, Bright's disease of the kidneys is the basis upon which these symptoms are engrafted. In these cases and fn yellow fever, an acute cholasmia or admixture of bile with the blood is the most decided of all the pathological phenomena. The group of symptoms and lesions in the Texas disease is therefore well established, and corresponds to the action of a not unusual combi- nation of causes, as well as to that of the yellow fever miasm. The application of the term yellow fever to the Texas disease of cattle, is warranted both by its pathological characteristics, and by the source of the contagion. From examination of the liver of yellow fever, I am confident that the same injection of the biliary radicles would be found as in the Texas disease, could the liver of the former be obtained under the same conditions that revealed that structure in the latter. The pathological alteration in the liver of yellow fever is not a fatty degeneration merely, as is often asserted. The boxwood color can be derived from the biliary secretion only, and the liver of the Texas disease, and that of yellow fever, present precisely the same appearance when examined a number of hours after death. The yellow coloration in the Texas disease is undoubtedly due to an admixture of blood with the bile at its source, or to a superabund- ance of haematoidine from broken down blood-corpuscles in that secretion, and such may be considered the cause of the peculiar yellow coloration in whatever disease it may be found. State Agricultural Society. 1145 Description of Plates of Microscopic Anatomy. Plate No. 1. a, a, Normal blood discs, h, b, Shriveled and crenated blood- corpuscles of the diseased blood, c, c, Flocculi from liquor sanguinis, d, A crystal of cholesterine ( i) from serum. (1,000 diameters.) Plate No. 2. Bile, a, a, Yellow granular flocculi of bile, b, A cast of a branch of hepatic duct, c, c, Crystals of hasmatoidine. (500 diameters.) Plate No. 3. Urine, a, a, Casts of tubuli uriniferi, consisting of coagulated blood, b, Element of epithelium, c, c, Blood discs. (500 diameters.) Plate No. 4. Section of the liver. (50 diameters.) a, a, Yellow translucent center of acini, b, b. An opaque zone of mingled fatty degeneration and yellow discoloration, c, Capsule of Glisson between acini. Plate No. 4k- Appearance of a fragment of liver, a, a. Portions of retic- ulum of bile ducts, b, b, Hepatic cells, filled with granules of fat. (400 diameters.) Plate No. 5. Reticulum of bile ducts within an acinus injected with the yellow tenacious bile peculiar to the disease, a, Reticulum, b, b, Hepatic cells con- taining globules of fat. c, A separate hepatic cell with its portions of reticulum. (500 diameters.) Plate No. 6. Liver cells several hours after death. The coloring matter has passed from the reticulum into the cells, a, Nuclei, b, Globules of fat. (1,000 diameters.) Plate No. 7. Kidney, a, a. Tubuli uriniferi of kidney (their epithelium filled with granules of fat), containing extravasated blood, b, Fragment of epi- thelium. Plate No. 8. Spleen cells and nuclei of splenic pulp, a, Normal element of nuclear epithelium, b, b, The same enlarged, their nuclei filled with granules of fat. c, c, Cells containing colored corpuscles, like blood-discs. (1,000 diameters.) Plate No. 9. Elements of splenic pulp during convalescence. The cells are regaining their natural size, a, a, Homogeneous yellow granules, b, b, Aggre- gations of the same, c, A muscular fiber-cell, d, Element of nuclear epithelium regaining its normal size, e. Element of epithelium filled with granules of fat. f, Blood discs. (1,000 diameters.) Plate No. 10. Micrococcus found in bile and blood. 1. Appearance in fresh bile. 2, 3 and 4. Development of No. 1 in bile. 6. A variety of cryptococcus containing crimson granules from bile. 5, 7 and 11. Development of cryptococcus planted on a slice of apple ; formation of filaments. (1,500 diameters.) Plate No. 11. a, a, Cryptococcus guttulatus from intestine of rabbit, b, b, Development of the same when planted on a slice of apple. (1,500 diameters.) Plate No. 12. Development of cryptococcus from bile on a slice of apple. Penicillium. (1,500 diameters.) Plate No. 13. Crystals of hsematoidine from diseased kidney — the same existed in extravasations of blood into the cellular tissue surrounding the kidney. (1,000 diameters.) 1146 Annual Report of New York [Note. — The interest that has been awakened by the announcement of the first results reached in this line of investigation by Dr. Stiles, is reasonable, and the importance of the ultimate truths and results to which it relates, warrants the continuance of this investi- gation. The following communications which Prof. Hallier sends to us from Jena, present the first results he has reached, and fully sub- stantiate the conclusions previously reached by Dr. Stiles. As such elements of useful knowledge grow best by accretion and criticism, none of them should be withheld from publication. The litho- graphed figures upon the opposite page, are fac shniles of Prof. Hallier's penciled sketches. In the course of correspondence, this renowned Mycologist of the University of Jena, Prof. Hallier, early in October last, made the following statement to us: I scarcely know of anybody "whom I might entrust with scrutinies of such importance as those mentioned in your letter. ***** ^he method of cultivating these small plants, I discovered by very hard work, by a gi'eat number of researches continued through years, and now I believe myself able to discover the origin of every vegetable cell found in the human or animal ********** If you can send to me bile and blood of the infected cattle, I hope I shall be able to find out the origin of the cryptococci or micrococci. * * * * With my best regards, Most truly yours, (Signed) E. HALLIER. In his second communication. Prof. Hallier writes as follows: Jena, December 5th, 1868 To Elisha Harris, M. D., etc., etc.: Sir — I am very greatly indebted to you for sending to me a vial filled with bile of the infected cattle. I received it safely on the 22d of last month. I immedi- ately examined the contents of the vial, and found two different kinds of vegetable cells. (1.) Micrococcus (of some kind of fungus) in large masses, many of them single and globular (a), others single and long shaped (b), forming mycothrix chains (mycothrix ketten), others in a state of division (c), and sometimes forming large or small colonies (d), (micrococcus kolonin). (2.) Cells of much larger dimensions, and of the shape of crj^ptococcus, or rather, intermediate between cryptococcus and arthrococcus, most of them sprout- ing like true cryptococcus, but sometimes dividing and forming two equal limbs . After this examination, I began a series of cultivations with the vegetable (micro- coccus) cells. (1.) Cultivation upon an object glass (without a covering glass). The food provided for the fungus was composed of boiled spring water, a portion of starch, sugar, and an equal portion of phosphate of ammonium (phosphorsaure ammo- State Agricultural Society. 1147 niak). The object glass was put into a culture apparatus (Hallier, Griihrungs erschcinungen, p. 13, fig. 3). In this apparatus in my room, at a temperature of 20° centigrade,* the micrococcus was in rapid augmentation on the 24th of Novem- ber.! The micrococci were swelling and forming the larger cryptococcus-like cells. In the first days of December, many of the larger cells germinated and formed long filaments with many branches, and of a brownish color. Similar results I have obtained in other cultivations. (2.) Cultivation on a lemon (deprived of its shell) in a similar apparatus. The micrococcus forms large cells in the same manner as in the first cultivation (December 3d). On many spots the micrococcus is augmenting to such a degree as to form large colonies. Near the outline of these lobular colonies the micrococci swell and become large cells of the same kind. In a few days the colonies only consist of these cryptococcus-like cells. These colonies become rather hard, and at last have a diameter of 0.001 m — 0.002 m. They are of a white color, and have the appear- ance, and, according to my opinion, even the function of a sclerotium. As soon as the sclerotium is formed, all the cells in it germinate in the same manner as the single cells. Of course, they form great masses of filaments, or rather forests of filaments, as seen in figure 7, with a low power of the microscope. The filaments are of the same size and shape as in the first cultivation. In the midst of the fit tie forest they form much larger cells, or rather fruits of that kind, which I called " Schizosporangia," divided by sheetsf in one, two or three directions. As you may see by looking at these few figures (No. 8), the shape of the schizos- porangia is very various. The schizosporangia have the utmost resemblance to those whose micrococcus I discovered in the blood of the glanders of horses, and also in syphilis. Only look at the figures Nos, 11, 18 and 21. On the upper surface of the sclerotia are forests of filaments, and these filaments never form schizosporangia, but a cladosporium fruit (see No. 9), also similar to a correspondent form of the glanders and syphilis fungus. As soon as the soil begins fermentation, the cladosporium branches alter and take the form of the same peni- ciUium, which I met with in the syphilis exploration (Figs. 12 and 13.) It is possible that our fungus is no other than the " coniothecium syphiliticum," whose origin till now is unloiown. * * * -^g ^^j^ ^j. ^y^^ conclusion of the diflFerent cultivations. These are: (3.) Cultivation on the surface of a cork, disinfected by submersion in alcohol for an hour. Till now the result is the formation of the same sclerotia, and just now the cells of them begin to germinate. (4.) Cultivation on the surface of a potato (the skin cut ofi"). Till now only vast augmentation of the micrococci. (5.) Cultivation in a solution of sugar and phosphate of ammonium. (The apparatus I have not yet opened.) (6.) Cultivation on albumen of eggs, with a small portion of sugar solution. Great apparatus (Grosser isolation apparatus) [Gahrungserscheinungen, p. 14, Fig. 2.] This cultivation has the purpose of discovering the type form (anserophy- tische morphe§) of the fungus, and may require two months' time. •68° Fahrenheit scale.— E. H. ■j- The second day after Prof. Hallier's reception of this specimen from New York. J Partition faces. § Anserophytic form or mode. — E. H. 1148 Annual Report of New York I have already succeeded in discovering three forms of the fungus : 1. Schizosporangium. 2. ^rophytic spores (ripe), mature. 8. ^rophytic spores (unripe), immature or " mold " form. There still must be discovered three other forms : 1. The unripe form of the schizosporangia (mucor or mold). 2. The anserophytic spores (ripe). 3. The anaerophytic spores (unripe), oidium form. As soon as I succeed in getting any more results I shall write to you. I hope you still succeed in getting the same forms in your cultivations. # * * With my best regards, Most faithfully yours, (Signed) ERNST HALLIER. Manifestly, it is not a common and familiar form of oidium or penicellmm that Dr. Stiles and Prof, Hallier have been studying, or they would quickly have recognized and named these beautiful fungi. The fact is instructive, that in the cool weather of October we were able to send a specimen of the infected bile from New York to Jena — four thousand miles — without change, and with the spores alive, and evincing all the capabilities of higher develop- ment into plant-like forms. It is not the present habit of science to depend upon hypothesis, because true knowledge patiently awaits demonstrations and abso- lute facts; but every reader of Prof. Hallier's letter and Dr. Stiles' report concerning this parasite will not fail to remark how per- sistent and enduring is its own vitality. It survives and flourishes for months after being taken from the gall bladder and the blood of the infected bullock; and there is reason to believe that it would live and grow in muddy streams on various kinds of algae. It is cer- tainly an interesting and suggestive fact that, so far as the researches of Dr. Stiles and Prof. Hallier have extended (to date of this report), the type of fungus which they have found developed from these spores is one that finds its home in the carex, the lolium, and the wheat-like or tilletia grasses. Whatever results may be attained in the researches now in progress, including the examination of grasses, the cultivation of the fungus upon them and in fluids, as well as the study of the development of the fungus in its several stages, will be equally interesting to herd-farmers and to hygienists. The results, whatever they may be, shall be given to the public through the proper channels. E. H.] State Agricultural Society. 1149 [Note — After the manuscript for this report had been delivered to the Board of Health, and arranged for the printer, the follow- ing communication was received January 11th, from Professor Hallier: Jena, December ISth, 1868. Dear Sir — To-day I can give you the results of my cultivations of the fungus which you sent to me. As I mentioned in my last letter to you, the fungus of "which the micrococci and the cryptococcus-like cells take their origin, is a species of the genus coniothecium. This form of coniothecium is the true brande form (anaerophytische morphe) of the fungus, growing only in the interior of the strata, or at least not under the iniiuence of the open air. You get it best by cultivating the bile on a lemon deprived of the exterior portion of the pericarpium. The germinating cells of the fungus form, on most parts of the lemon covering, the penicillium form of which resembles very much the penicillium syphiliticum: On the dryer spots of the lemon you will see filthy masses of a dark greenish color. If you put these masses upon the object-glass, and put a drop of caustic potassa to it, you will very clearly see the coniothecium fruits surrounded by many filaments of ripe cladosporium with long spore chains. Upon dry vegetable matters, like disinfected cork or potatoes, I have seen the cells of the fungus (spores) germinating in the same manner as on the lemon ; but instead of the coniothecium (in every one of my cultivations of these spores), the filaments bore the true schizosporangia of which the following figures give you an idea.* The schizosporangia are formed on the ends of brandies, not interstitial like the coniothecium. The fruits are of very different forms, and of a dark brown color ; they are scarcely to be seen by the naked eye, but with a lens you see black spots on the cork or potato, and these spots are covered with fruit-bearing fila- ments. On the potato the schizosporangiae occasionally do not ripen, and in this case, if the potato is moist, the unripe or mucor-form appears. (See c, c.) Notwithstanding the great similarity of the coniothecium syphiliticum and the species here described, they are entirely different. I tried to cultivate the syphilitis fungus at the same time (on the same days that I was cultivating the spores from diseased cattle), and upon the same substances, but never got the schizosporangia under the same circumstances as those observed in the cultivation of the fungus fi-om the infected cattle in America. Our coniothecium from the bile of the infected animals was unknown till now, and for this reason, allow me to give it the name of Coniothecium Stilesiarium, in honor of the first discoverer of the parasite vege- table-cells in the blood and bile of the infected cattle. Of this coniothecium, we have now succeeded in getting all the ripe (mature) and unripe (immature) forms. • See plate 33, figs. 4 (b), 7, 12 and IS. 1150 Anxual Report of New York 1. Type-form (anserophytic spores) ^ 2. Schizosporangia (Septosporium, ac- [ ripe ] Coniothecium Stilesiarium.* > cording to the ancient system) Mucor [ unripe ] Oidium-like filaments.! ) Coniothecii Stilesiani. 3. Aerophytic form : [ripe], Clodosporium ; [unripe], Oidium-like filaments (according to the system, Coniothecium Stilesiarium). Perhaps you may succeed in finding out the places where this coniothecium grotcs in nature. At all events, it is a parasitical fungus, groioing on plants, and to be looked for in the food of the wild bullocks. I began a new series of cultivations a few days ago, and if the results in any point are different from the first cultivations, I shall write to you another time about this matter. With my best compliments to Prof. Stiles, I remain Most respectfully yours, ERNST HALLIER. Db. E. HabriSj Metropolitan Board of Health, New York.} * See plate 33, figs. 4 (b), 7, 12 and 13. t See plate 33, fig. 4 (a). State Agricultural Society. 1151 n PEOF. CHANDLER'S REPORT UPON HIS CHEMICAL INVESTIGATIONS. School of Mines, Coluimbia College, New Yoek, December 1st, 1868. To E. Harris, M. D.: Dear Sir — I have the honor to report, herewith, the results of my investigations of the blood, bile, etc., of diseased cattle, which you have sent to me from time to time. The analyses are as accu- rate as can be expected of such comj)lex and putrescent fluids, during the warm summer months. The first samples spoiled on our hands, so that the analyses could not be completed. I avail myself of this opportunity to call your attention to the valuable services of my assistants, Dr. Paul Schwitzer, Mr. F. A. Cairns, and M. D. Wheeler, Jr., A. M., E. M., who have been my co-laborers in this investigation. Eesj)ectfully yours, C. F. CHANDLER, Ph, D. 1152 Annual Report of New York Oi O 0-*0 OOO O O O GO lO t^ 000 a (M O O^O OOO O O O 1— 1 O CO 000 o Oi O OOO OOO OOOOOO 000 EH Oi O OOO OOO OOOOOO 000 ■" I— (I— ll— 1 I— (I— IrH I— li-Hi— (t— li— ll-H r-H I— 1 1—1 m O t- O O t— 1 00 C<1 O T-HOt^GOCDrH 1—1 00 1—1 CO «ri 05 00 00 fo «o 00 I— 1 •* oo o t^ oo 02 CO I-H 1—1 Eh CO 00 00 t- 1 as to Tfi 05 05 CI CO -* (N (M Ci t^ CO 0-; (N • • • • ■ • a (N CO t^ -^ CO !>. c CO 00 OS -^ Tfi "5 g^ I— 1 I— 1 (J^ 1—1 1* coco . • 1 00 (B I 1 . a 00 i-tO CO (M C^ • a Ph •* CO 1—1 1— 1 ^ • , 00 0000 Cf5 t^ 00 • n3 2 <-t QC 001 tr- io UO ^ CO J CO (M 00 CO I— 1 01 lO (> 1 1— 1 CO C5 Oi 10 oc* CG 1^ 1—1 ■* CO (M 10 ■— 1 t— C 5 CO CO CO C5 i-H CO oc '^ CO r-H ■* lO oc 3 cq -H CO 00 OS CM 0- ^H I— 1 iC 01 CO ►J D n (M 00 •<# <^ r- ^ (^"l c 5 CO -* CO (35 10 r- lO CO 00 »0 •* ^ ^ t- 00 CO 1—1 t- Oit^Oi ^ 00 oc 00 00 00 oc 000 ) 00 t^ 00 00 00 00 t^oo t— t- 1- 1- -U • 1 " • 1 <1> " C -^ P CO ^ rH m CO 13 C C « m c2 : . . a, f :t3o71,o S^ S . ' — 1 rp ' — 1 r/1 p, CO w EH M ,0 . CO • CO o o to c ^ .^ O) w g -2 > TS • CO CI 7< tC ii \-i -5 '.•^ end "cc^ ^-^ . fc< m 0) -UJ . +J •'- B oj nc! j3 ■♦^ ^ > g CO =S ^ ^ p:< a^^ W H O n PS o u w ■73 c3 -kJ .^ « c ^ c § g^c Oao§^^ CO ■ S h ^--5 5 J .2 • S S fC = ^o: ><-M • CO i^'-^ '^ —< m H K .F,.„cg CJ C3 QJ 2 3 c c g c t^ S a f^ • "S "^ - fa '*-' >C3 '^ . « =2 s- • -S-iij'^ . pq ^ fa pq (X! g a feX) W) bfl-ff "S -^ 3 a BB a|_| 3 -U ^ -W ^ i, O, CLia, &,->:? -w 3 C) (X> aj 03 V W 202 aicoccOO State Agricultural Society. SERUM FROM ABDOMINAL CAVITY. 1153 DATE. Water. Solids. Fibrin, Blood Cor- puscles Albu- men. Fat. Extract- ive mat- ter. Salts. Total. Aug. 30 Sept. 4 Sept. 9 Oct. 11 940.8 963.8 787.7 815.6 59.2 36.2 229.9 184.4 7.7 40.6 27.9 157.6 IfiS fi— "h'.K 3.1 5.9 7.8 2.0 39.1 7.4 1000.0 1000.0 ,1007.6 1005 4 10.7 9.3 21.9 THE BILE. DATE. Water. Solids. Specific gravity. Fats. Mucus. Chelates etc. Salts. Total. August 26 Sept... 4 Sept... 4 Sept... 9 Sept... 11 Sept... 14 Sept... 25 October 1 October 12 928.7 941.9 920.2 915.5 944.8 886.9 865.4 883.5 842.1 71.3 58.1 79.8 80.5 55.2 113.1 134.6 116.5 157.9 2.15 2.44 6.37 1.51 62.8 54.1 'ii'.46* 'i4!76" 13.10 13.70 1000 1000 1000 1000 1000 1000 1000 1000 1000 'ioieio* *i63o!5' 1043.4 1053.6 3.16 11. IC 66.2 1.04 17.05 94.9 THE URINE. DATE. Water. Solids. Specific gravity. Albu- men. Salts. Bile. Reaction. Total. ' 932^5 974.5 953.5 67^5 25.5 46.5 1028.0 1027.0 1014.0 1030.1 none 42.90 7.90 0.06 "5!9' 2.7 0.7 none none none none alkaline alkaline 1000 1000 1000 1000 Sept... 9 Sept... 11 Oct.... 11 THE LIVER. DATE. Water. Solids. Fats. Salts. Total. Remarks. October 11 740.5 766.8 773.1 707.1 259.5 233.2 226.9 292.9 62.5 66.1 90.1 88.6 41.1 1000 1000 1000 1000 October 11 Large lobe. Small lobe. October 11 October 23 [AG.] 73 1154 Annual Report of New York VII. TITLES AND DESCRIPTION OF PLATES. Plate I. ' : Appearance of animals in the acute or obvious stage of the Texas cattle disease. Fig. 1. Sliowing the feeble animal supporting himself by locking his horns in a fence ; back arched, hind legs wide apart, throwing the weight of the body forward, taU retracted, and ears drooping. Figs. 2 and 3. Showing the drooping head, protruded tongue, arched back and yielding hind-quarters. Fig. 4. The fallen animal in the last stages of the disease preventing himself from rolling on his side, by twisting his head spasmodically in the opposite direc- tion. Plate II. Carcass of a bullock in the last stage of the Texas cattle disease laid open, in order to show the color of the muscular and adipose tissues. [This is a sketch of one of Mr. Thomas' herd from Indiana.] Plate III. Sections of mucous membrane of abomasum, showing ulceration and intense con- gestion. Fig. 1. Pyloric portion of abomasum showing erosions of the surface covered with blood, blackened by the action of the secretions of the stomach. Fig. 2. Section of a folding portion of another rennet stomach, showing a more, chronic ulceration, and a higher grade of surrounding inflammation. Fig. 3. Folding portion of abomasum showing chroaic erosions and intense con- gestion. These three figures are taken from Texas cattle. Plate IV. Omasum and abomasum showing slight congestion of the layers of the former,; and intense inflammation of the folds of the latter. a. Omasum ; b, layers or maniplies ; c, abomasum ; d, small intestine. Plate V. Pyloric portion of abomasum and commencement of small intestine, showing inflammation and ulceration of mucous membrane of the former. Plate VI. Sections of pyloric portion of abomasum, showing congestion and ulceration. State Agricultural Society. 1155 Plate VII. The fourth stomach, showing congestion and deep blackened erosions. Plate VIII. Accidental ulcer of upper lip and portion of rectum Fig. 1. a. Ulcer of upper lip; h, b, rami of lower jaw. Fig. 2. a. Mucous membrane of rectum, its longitudinal folds inflamed and covered with minute extravasations ; h, b, adipose tissue. Plate IX- Mucous membrane of coecum and sections of abomasum showing hypertrophy of the follicles. Fig. I. Mucous membrane of coecum, presenting patches and striations of congestion and extravasation of blood. Figs. 2 and 3. Sections of mucous membrane of folds of abomasum showing the closed follicles enlarged and prominent on a surface of congestion. Plate X. Bladder everted, mucous membrane covered with petechise and extravasations. a, Urethral portion inflammed and oedematous; b, fundus marked by deeper congestion and larger extravasations. Plate XI. Sections of inflamed duodenum and rectum. Fig. 1. Mucous membrane of duodenum intensely congested and cedematous. Fig. 2. Mucous membrane of rectum intensely inflamed, its longitudinal rugas cedematous commencing gangrene. Plate XII. Sections of mucous membrane of abomasum inflamed, and recovering from sloughs, &e. Fig. 1. Mucous membrane inflamed and covered with blood that has been extra- vasated upon the surface, and blackened by the gastric secretions. Fig. 2. Mucous membrane of abomasum of a Texan highly inflamed, the edges of its folds sloughed and thickened. Plate XIII. Pyloric portion of abomasum showing extensive slough. Plate XIV. Sections of mucous membrane of ileumj showing congestion of longitudinal and tranverse folds. Plate XV. • Mucous membrane of omasum, abomasum and bladder ; intense congestion and petechial extravasation. Fig. 1. Mucous membrane of omasum, with ecehymosis and papillary projections. Figs. 2, 3 and 4. Mucous membrane of small intestine reddened by congestion. Fig. 5. Bladder in miniature, showing petechia on a ground of diffused conges- tion and extravasation, a, Urethra. Fig. 6. Mucous membrane of No. 5, on natural scale, appearance of petechias. 1156 Annual Report of New York Plate XVI. Posterior surface of liver atid gall bladder (reduced in size), showing distended gall bladder. Plate XVII. Appearance of enlarged and distorted liver; diaphragmatic surface (weight 23 pounds. a. Section showing color of parenchyma immediately upon being cut. Platr XVIII. Spleen entire, reduced, and sections. Fig. 1. Spleen (reduced) showing the mottled greenish color of the peritoneal surface. Fig. 2. Section of spleen (natural scale) and actual appearance of the surface. Fig. 3. Portion of spleen of another animal, showing congestion of capsule, and gashed to show the pulp. Plate XIX. Kidney laid open, in order to disclose the interior congestion and discoloration, and showing cortical portion, tubular portion, and pelvis with surrounding fat; aU these parts blackened and intense congestion. Plate XX. Kidneys entire (reduced) in different stages of congestion. Fig. 1. Same animal as Plate XVII. Plate XXI. Section of pyloric portion of abomasum, several weeks convalescent, and of rectum, showing congestion and ulceration. Plate XXII. A congested and ulcerated abomasum. Plate XXIII. Sections of skin, liver and spleen. Fig. 1. Portion of skin shaved, in order to show its jaundiced hue. Fig. 2. Fragment of liver showing color of surface, and the ramifications of the distended biliary ducts. Fig. 3. Portion of spleen showing congestion of superficial blood vessels and coloration of parenchyma. Plates illustrating the microscopical researches, seven in number, already described. Plate XXXII illustrates Prof. Hallier's study of the fungus parasite of the blood and bile in the cattle disease. State Agricultural Society. 1157 ym. WITH WHAT WELL DESCRIBED DISEASES IS THIS TEXAS CATTLE DISEASE ALLIED ! Having alluded to the fact that the first groups of the diseased animals that arrived at the Metropolitan herd yards exhibited sjmaptoms which led us to believe that the malady perhaps belonged to the brood of contagions known as anthrax fevers, some pains have been taken to inquire carefully into its chiaf points of resem- blance and difference, compared with those fevers, and with the milzbrand and kindred disorders which prevail on the continent of Europe. The very first dissections that were made clearly demonstrated that it was not the intestinal typhus, for the small intestines were in no cases marked by any of the lesions of typhoid enteritis which is prevalent in the lowlands of Holland, Belgium and Hungary. Considered in regard to all the phenomena and pathological changes noticed in the first two groups of diseased cattle, this disease seemed to require a description that had hitherto not been given in any treatise on epizootics. From the Western newspapers the fact was learned, that Prof. Gamgee and others regarded it as similar to the "darn" of Aberdeenshire. Prof. Liautard, with whom we fre- quently conferred during the autumn, did not attempt to give any name to the disease. The same was true of Prof. James Law, the accomplished professor of veterinary science at the Cornell Univer- sity, Ithaca,. N. Y., whose attendance we had the good fortune to secure at one of the last post mortem examinations made at the National drove yards, One Hundredth street The latter gentle- man has, with characteristic thoughtfulness, kindly forwarded to us the subjoined communication relating to the points we are here examining: The " darn" as seen by us in Great Britain [Prof. Law is a native of Scotland] is usually a very mild affection. Its cause is agreed on all hands to be the inges- tion of irritant, resinous and astringent plants, as its common names — in England, 1158 Annual Report of New York wood-evil ; in Germany, holzkrankheit ; and in France, maladie de bois — would indicate. The symptoms are those of intestinal irritation, the colicy pains being often severe, with constipation ; the faeces, if passed, being coated with mucus or even blood, and in bad cases forming a tarry mass evidently due to altered and effused blood The urine, red or black, contains large quantities of blood-coloring matter and albumen. If seen in the early stages, measures directed to the obtaining of free evacuations from the bowels are almost always followed by a speedy restoration to health, so that I have never seen a fatal case. It is worthy of note, that it often prevails on the same lands with the anthrax or carbuncular affections, and appears then to be complicated by this disease, or modified by a similar cause. Roll, of Vienna, says there will sometimes appear " a gelatinous exudation into the sub-cutaneous areolar tissue, and extravasation beneath the serous membranes, showing a complication with anthrax. The malady begins with the appearance of gastro-enteritis, accompanied by renal irritation, scanty, red or bloody urine, great sensibility of the loins and intense fever, mucous and bloody fgeces, foetid and bitter milk, with not unfrequently spasms or convul- sions. The complication with splenic apoplexy (milzbrand) is seen, and may be shown by swelling and emphysema on the surface of the body." Hering and others speak in analogous terms, indicating its close connection with the anthrax affections, though whether only as a complication or a full develop- ment of the original affection, is open to question. Our English form rarely assumes this aggravated type, and seems quite wanting in the malignant proper- ties of carbuncular fevers, having, moreover, no specific virus like these latter. I ought to add, however, that in those European cases that prove so fatal, the autopsy shows points of resemblance to the Texas fever. Hering says there is '' inflammation and petechial patches in the stomach and intestines, the ingesta is dried, the mucous membrane cedematous, the liver and spleen enlarged, sometimes even to rupture ; the gall bladder distended, the kidneys contracted, a turbid effu- sion in the thorax, inflammation and petechige in the pulmonary organs, and a jelly-like effusion into the cellular tissue." The accounts, however, are too meagre, and as you will notice, the means avail- able in the present day have not been brought into requisition in the case of these diseases, so as to furnish data sufl5ciently numerous and accurate for purposes of comparison. I have already mentioned to you the general similarity of the Texas fever and the carbuncular fevers of Europe. I mentioned 'that one great distinguishing feature of the former was the absence of bacteria in the blood, though as these have been found in the blood of animals suffering from influenza and other affections, attended with a typhus diathesis, their presence is probably not an essential condition of the disease. What leads me to make special reference to this again, is the statement by Davaino, in his communication read before the j^cademie de Medicine (July 27th, 1860), that in addition to bacteria, the blood of anthrax patients contained special globular elements. " Globules, of a peculiar kind, are sometimes found ; they are regularly rounded off", and larger than the normal white globules, of which they have the appearance. They are united in small clusters in great abundance, and are composed of an outer cell of a bulbous appearance, reflecting in some a violet tint. In the center of this cell there are found several nuclei, the double outline of which is well marked. In some, these nuclei have degenerated into the sandy or granulous form, peculiar to the nuclei which are pro- State Agricultural Society. 1159 duced by fission, so that evidently we have under our eye an alteration of the elements, which are in a fair way of multiplication." This spore cell production I had altogether overlooked ; but now the question arises :. May not this be the same microphyte as you have so admirably shown in the blood of Texas fever, or, what would probably amount to much the same thing, a fungus, which demands much the same condition of blood for its development ? The want of any testimony to its presence in the bile, and the ignorance concerning the special action of the bile in breaking up the blood globules, affords no pre- sumptive evidence of the non-existence of these conditions, since the presumption is that no test was applied. In contagious properties, again, they agree in some remarkable points. The carbuncular fevers are inoculable, and usually contagious, but the contagium is rarely or never conveyed through any other medium than the blood, tissues and discharges of the diseased animals — rarely showing what the French call a vivius volatil — and evidently requiring some, not well defined conditions, for its trans- taission ; hence, in many cases — indeed, the majority of cases in Great Britain — it gives no evidence of a contagium unless inoculation is resorted to. * * * With much esteem. Yours very faithfully, (Signed) JAMES LAW. To E. Harris, M. D., Metropolitan Board of Health. Plainly enough, it Avill be easy for European medical observers of milzbrancl, and the whole group of ailthracoid diseases of cattle, to ascertain whether these destructive maladies which they witness^ are or are not similar to the Texas cattle disease. Prof. Virchow^ of Berlin, Dr. William Budd, of Bristol, and the ablest pathologists in Europe, think they are able to trace a direct relation between the carbuncular or anthracoid fevers of domestic cattle and the malig- nant pustule in man. Such a relation is now admitted to be the source of this terribly fatal malady. But in reference to the Texas cattle disease, the fact seems well established that it does not pro- duce malignant pustule, and that while it corresponds with the destructive epizootic fevers which Professor Law has carefully described in the foregoing letter, it nevertheless seems to differ in some essential points from them. It is highly desirable that all the anthracic or carbuncular fevers should be studied with the same care and exactness as the Texas fever. Professor Law'^s statement concerning the actual analogy between the milzbrand, of Europe,, and the Texas fever, are eminently suggestive; and we feel greatly obliged to that learned writer for this valuable contribution from his pen. It may yet be found that the marshes of Hungary and the swamps of the Vistula occasionally produce a disease quite- similar to the Texas cattle fever. 1160 Annual Report of New York IX. FACTS AND DEMONSTRATIONS ADDED TO PHYSIO- LOGICAL AND PATHOLOGICAL KNOWLEDGE. First. — Hie demonstration of the rapid dissolution of the red hlood-globules in the last stage of the disease and immediately after death. This was plainly true in the first cases examined by Dr. Stiles; and on the 10th of August, he remarked that after the blood, flowing from the carotids of infected bullocks, had stood for a few hours in stoppered vials, scarcely a trace of blood-globules could be found, excepting such broken and shrivelled as he has described in the first plate of his microscopy of the blood. And, while experimenting with a solution of the morbid bile from the same diseased bullocks, Dr. Stiles noticed the fact that the red globules of the blood were swept into solution almost as suddenly as snow flakes would be when falling into water. Second. — Facts connected with the ultimate reticulum of biliary ducts and the morbid cha-nges in the liver and bile. The discovery that was made by Dr. Stiles (when working in the field with the microscope, on the 13th of August), of the reticulated structure and distribution of the ultimate biliary ducts of the liver, not only added a fact of great interest and importance in progressive physio- logical knowledge, but this discovery was ,from the first associated with pathological conditions, the later studies and better under- standing of which have led to comprehensive, exact and highly important practical conclusions in regard to symptoms and patho- logical changes which had hitherto been most important, but at the same time most difficult, if not impossible, to understand. We refer to the mechanical and pathological conditions which in thit' disease manifestly produce cholsemia, and to certain demonstrations here alluded to concerning the morbid condition and destructive efiects of the bile as witnessed in this disease. The studies which Frerichs and other high authorities have given to this class of facts without such means of demonstrations, have been corroborated State Aqricxiltural Society. 1161 and placed upon a more definite practical footing by the results of these researches. Third. — TJie demonstration of consecutive jpathological changes, and of their relations to the fatal result. No other pestilential or febrile disease, whether epidemic or epizootic, has furnished to medical observers such a complete and consecutive series of demon- strations of the steps by which disease progresses from its incubative beginnings to perilous and destructive changes in tissues and proxi- mate elements to obvious symptoms and exclusive phenomena, until death terminates the pathological record of events. Con- sidered with reference to the progress of medical knowledge and hygienic measures, in regard to epizootics and enzootics, as well as in regard to epidemics and certain of the spreading pestilences that depend upon contingent circumstances that hitherto have not been well demonstrated, the results reached in these investigations may justly be regarded as in the highest degree encouraging and instructive. The successful study of the essential morbid changes that occur during the progress of this disease in the blood, the bile, the liver, the most vascular and constricted portion of the stomach and the spleen, and lastly, the explosive phenomena, the destruction of the blood-corpuscles, the waste of blood elements of the kidneys, and the morbid alterations that occur in those organs, and in conclusion, the phenomena and circumstances of death, together with that impressive, and truth-telling signet which the damaged and broken blood-corpuscles leave in the tissues, cavities and fluids into which the spoiled and stagnant blood has oozed and left crystals of hsematoidine, singly, and in this associa- tion, constitute such a series of consecutive and well coordinated events in the disease as rarely has rewarded the toil of medical researches. And notAvithstanding more remains to be learned than all that hitherto has been demonstrated, it is certain that some substantial progress has been made in that kind of knowledge by which the mysteries of transportable pestilences will ere long be unmasked and exterminated or effectually controlled. And when we consider that, had it been a human pestilence, this disease could not have been studied in this manner without violating the common sentiment of regard for the dying and the dead, the medical men who pursue such investigations upon the food-animals, may justly claim that by such studies as these they confer a three-fold benefit upon mankind; for in addition to the protection of human foods 1162 Annual Report of New Yore aiid myriads of valuable cattle, a correct and controlling knowledge of human pestilences is promoted, as it could be in no other way. Fourth. — The re-demonstration of the so.ine law of ground-incu- hation, or defvelojpment of a contagium deposited upon the soil from the bowels. This very important law or truth concerning cer- tain infective principles or substances was first demonstrated by Prof. Pettenkofer, of Munich; and the demonstration, as the Metro- politan Board of Health very well knows, related to the propagating principle of the Asiatic cholera. Dr. Wm. Budd and Dr. Snow, in England, practically taught this doctrine, without full demonstra- tions, at the same time that Pettenkofer was tracing out the complete evidence upon which this law is now founded. As in regard to the infective cause of cholera, so in regard to the Texas cattle disease, the bowels of the living, and in some instances apparently healthy, individual carrier of the pestilential germs, may evacuate — with excrement, those germs so completely developed that they may at once begin the fatal and incubative work of infecting other indi- viduals; or, on the other hand, the germ development in such excre- ment may be so incomplete or immature ("unripe," as Professor Hallier says of the aneerophytic spores), that the surface of the soil, or the herbage on which the excrement is dropped, must serve as the nursery and " hot-bed " for nourishing them into the advanced or infective and poisonous stage of development (the " ripe " state, Prof. Hallier), before the blood and tissues of the exposed and healthy individuals can become infected. In the present state of advancing demonstrations in regard to the pestilential contagium of cholera, this would scarcely be regarded as theoretical language, much less does it now seem to be merely theoretical in regard to the Texas cattle disease. Upon this subject we need only refer to the abstract of correspondence and of authenticated evidence in preceding sections of this report. In the States of Illinois and Indiana, the proofs upon this point concerning the incubation or maturing of the excrement contagium during an interval of greater or less duration after it was dropped upon the ground, are so abundant and convincing, that many of the farmers seized upon the logical interpretation of their own peculiar experience and classes, and emphatically though, somewhat rudely gave expression to this wonderful yet now easily understood doctrine, that Pettenkofer demonstrated when analyzing the history of cholera in Bavaria in the autumn of 1848. A vast quantity of evidence (experience and record) relating to this anomalous habit of the infective cause of State Agricultural Society. 1163 the Texas cattle disease, is constantly coming into our hands, and it will in due time be analyzed and the results made public. Fifth — Aid in elucidating important physiological and patho- logical questions connected with yellow fever. While summing up and analyzing the results of these investigations concerning the "Texas cattle disease," we have been deeply interested in the con- tribution which these results make to practical knowledge of some of the most essential questions that have, in the past fifteen years, been started by physicians in the study of yellow fever. The com- piler of this report having witnessed and professionally examined several hundred cases of this pestilence, and made dissections of nearly one hundred persons that died of it, was prepared to notice the j)oints at which the results of the present investigations apply to the questions that have arisen in the study of yellow fever. In regard to these questions we will here notice the following points: In 1853, Prof. Alonzo Clark, of New York, discovered and described the characteristics of the fatty change and the peculiar coloration that occur in the liver in cases of yellow fever. He also described the nature and cause of the strange coloration which characterizes the liver in malignant remittent fever. Dr. T. H. Bache and Dr. Stowardson, of Philadelphia, made similar researches and reached similar results. The microscopical investigations by Dr. Lyon in the last epidemic of ^'■ellow fever in Lisbon, and simi- lar studies by Dr. S, Fleet Speir, of Brooklyn, confirmed the medical opinion of the profession that the most constant of any of the anatomical changes in the latter malady, is found in the liver, and in a certain kind of coloration which attends the malady as a resultant of the dissolution of blood globules. Whoever peruses this report, should, if possible, read the Prize Essay of Dr. Speir in the Transactions of the American Medical Association (vol. xv, 1864), and consult the letter from Prof. Clark in the first volume of Dr. La Roche, on yellow fever, and the report on yellow fever in Lisbon in 1858, by Dr. Robert Lyon. These distinguished pathologists found that the pestilential destruction of blood-globules, the presence of the resulting hcematoidine, or of hsematine, from w^hich it is derived, and the acute fatty change in the ultimate structure of the liver, are the most essential pathological events in that malady. But the 0]Dportunity for studying the structural (morphological) alterations in the liver, the blood, the spleen and the kidneys in fatal cases of yellow fever, have not given the facili- ties for precision in results of microscopical inquiry (because 1164 Annual Report of New York not made in every stage of the disease and of convalesence, and before any jpost mortem change was possible) which have been afforded by the infected cattle for the examination of these vital structures. And it is one of the rewards of the latter class of labors that they elucidate and verify the chief deductions that have been made by the learned physicians whose researches in yellow fever are here mentioned. In concluding this brief note upon the aid given to clearer demon- strations in pathology by these investigations, we would not omit to notice the very instructive researches of the late Dr. Daniel Blair, chief medical officer of the British military establishment in Demerara; for when he died in the midst of great efforts to dis- cover the true cause of yellow fever, sanitary science lost its most ardent inquirer into the natural causes of this pestilence. The latest of his observations was so directly in the line of the demon- strations that have resulted from Dr. Stiles' investigations that we mention them in this place. Truly, scientific physicians are jealous only for the truth; and it will be noticed that Dr. Blair reached the verge of that important discovery which Dr. Stiles has made in regard to the actual ultimate structure of the biliary system. It was in a living patient in his hospital, and in some vomited bilious and bloody matter which Dr. Blair believed contained by chance some particles from the diseased liver cells that had floated into the duodenum and into the stomach with the bile. In April, 1856, Dr. Blair wrote to his friend. Dr. John Davy, of London, as follows concerning his microscopical examination of that fancied and but barely possible presence of debris of the liver: It (nitric acid, upon a certain specimen) enabled me to trace some of the tubules into the centre of the specimen; still more important, it enabled me to detect within them liver-cells, with their minute oil globules. * * * I think there can be little doubt that these tubules are the radical secreting ducts of the liver. May not these observations throw some light upon what I believe is still an undecided point in anatomy, viz., the precise manner in which the radicals originate in the lobules? To me, what I have seen seems a demonstration of the induction of Kiernan on this point. . Dr. Blair was describing a substance that his patient had ejected with some bile or vomit; and this observation came near being buried with its author. It was not a demonstration; nor would a thousand such observations have been a worthy basis for belief or assertion; but it has value as an observation, that we mention this fact here, because it belongs to the record of a most important dis- State Agricultural Society, 1165 coveiy and actual demonstration of essential facts in the anatomy and pathology of the liver, and particularly because this curious observation by Dr. Blair shows how difficult and obscure was the kind of knowledge which he sought by the bed of the dying and in the corpse of dead of yellow fever. (For a fuller account of Dr. Blair's latest observations, see his letters appended to the April and July numbers of the Medico Chirurgical Review, 1856.) 1166 Annual Report of New York L CONCLUSIONS. The field in which the investigations have been commenced is too large to admit of final conclnsions upon all the points of inquiry, in so brief a period, for analyzing the results of so numer- ous and varied an .assemblage of facts. Our deductions, therefore, must be regarded rather as landmarks and soundings, than as boun- dary lines, upon the shore of great truths. The conclusions that appear best established have important relations to practical ques- tions in hygiene and to the interests of herd farmers. FiKST. — The nature and jpathologtcal effects of the disease in beef cattle. The investigations prove that the disease is caused by a slowly incubating poison which operates in a fatal way upon the blood, and which also produces important structural altera- tions in the essential organization of the liver, the spleen, and the kidneys. Second. — The precise nature of the diseased sti-uctural altera- tions. The blood sufiers an impairment, and, in the fatal stage, an almost entire destruction of its most vital portion — the red glo- bules. It also suffers in its natural quality and richness, by the loss of albumen through the kidnej^s, and by other very serious kinds of impairment which are not yet understood, but which result iD actual destruction of the blood as a living element of the animal system. This spoliation and death of the blood {necrcemia) appears to be complete. No disease or poison known to medical men has ever presented a more striking example of an incubating blood- poison {toxoemia), and an ultimate termination by necr£emia or death of the blood. The anatomical lesions, or structural alterations in the liver, are unquestionably the first in the order of beginning, and of relation- ship and importance. The particular kind of morbid conditions in the secreting and circulatory organism of the liver would inev- itably contribute to the gradual aud final destruction of the blood, and also would induce the morbid changes that are observed it. State Agricultural Society. 1167 the spleen. Physiological principles seem fully to account for the engorgement, erosion and sloughing which occur in the tubular portion of the fourth stomach or abomasum. The spleen, in its engorged, diseased condition, would necessarily aid in producing the stomach lesion (erosion and sloughing) by its own failure to furnish outlet and relief to the engorgement of the vessels of mucous membrane of the rennet, and it could contribute in several ways to hasten the final dissolution of the blood. The engorge- ment and the acute fatty degeneration or change noticed in the kidneys, is one of the chief causes of the rapid waste of albumen from the blood; but the disease may, and not unfrequently does, go on to a fatal termination without being attended by any consid- erable amount of disease or change in the kidneys. The lesions or changes that have been observed in the other tissues and organs of the infected animals seem to be merely results of blood-changes and impaired vitality. Those lesions which are merely incidental to the really essential changes in the blood and in the liver and spleen, may, nevertheless, be recognized as aids in diagnosis of the disease in certain cases. They are, therefore, worthy of attention and description, such as we have attempted to give in several of the illustrations given in this report. Thied. — The jparasite that is found in the blood and bile of infec- ted cattle. Whether we regard it as a propagating and destructive cause of the disease, or simply as a concomitant, it is necessarily an important attribute of the pathological or destructive agency that operates upon the blood. The prolific brooding and growth of the fungus (micrococcus) is wholly dependent upon the living elements of the blood for its " soil and food " to grow upon. But the real significance and value of the results that have been reached in the researches upon this collateral element of the inquiry into the disease, promise much for practical hygiene as well as for herd farming; for, such complete demonstrations will lead to a kind of absolute knowledge that is much needed concerning the pestilential epidemics, as well as the destructive epizootics, and will lead to their entire prevention. Fourth. — The unfitness of the dying and the infected cattle for human food. If this question is raised by any persons, or on behalf of any commercial interest, it should at once be answered in gene- ral terms, that both the animals that are dying, and those that have lingered under the operation of the infection until the blood and viscera are diseased, are unfit for food. Practically the human XI 6 8 Annual Report of New York stomach can overcome most of the immediately poisonous effects of diseased flesh and animal juices used as food; but experience and teachings of physiology and hygiene unite in pronouncing unfit for food, all the cattle that reach the fatal stage of the ''Texas cattle disease," and all that have incubated the infection until the blood and tissues exhibit the morbid alterations which that poison produces. And as regards certain freshly arrived Texas cattle that are suffering the disease (as we now diagnosticate it by the post mortem evidences in them when slaughtered, and by emaciation, feebleness and their indescribably offensive breath and effluvium while living"), we can best express the conclusion that has been reached by the more precise kind of investigation, without here mentioning the details of evidence on this subject, by simply quoting the remark of an educated observer of the Texas cattle disease in Western Missouri. He says: " Who would knowingly eat the beef of cattle with such a pestiferous breath as these sick Texas cattle have? It can be no favor to the consumers of beef to have that article cheapened in the market by the introduction of such very doubtful, not to say injurious character." In plain words, cattle while suffering either from the chronic or the acute type of this disease ought to be withheld from the meat markets. Fifth. — The period or term of incubation. The term of incuba- tion or latent development of the fever poison in the second or northern groups of cattle that receive the infection, is clearly proved to be a period of variable duration, and that it varies from fourteen to thirty or forty days; but, that in the majority of instances, the full incubation and development of the disease is accomplished in about twenty days.* High temperature manifestly hastens the develop- ment of the disease. And the hunger, thirst and excitement of raihvay transportation aggravates it. But that even where the cattle become infected in good pasture, and under circumstances * This is a little more than four times the average and usual period of incubation of yellow fever in man. The troops that continued to be sent from France to the port of Vera Cruz during the recent occupation of Mexico by the French, were attacked by yellow fever under such exact conditions and periods of exposure by medical observation at the times of their arrival in port, that the medical ofi5cer8 had no difficulty in reaching the conclu- sion that the period of incubation of the infection (contagium) "was never less than forty-eight hours, and seldom more than four days." (Surgeon M. Croullebois on Epi- demic Yellow Fever at Vera Cruz in 1863. Recueil de Memoirs de Medicine, de Chirurge et de Pharmacie Militaire, Paris, December, 1868.) This result of observations by the French military surgeons, accords with observations upon the same pestilence in the harbor quarantine hospitals of New York, with this exception, that in this latitude we find that the period of incubation ranges from three to seven days, and that in cool weather the iaeubation term is longer than iu very hot weather. State Agricultural Society. 1169 that are favorable to the best health, the incubation is certain and aestructive; and, that with such conditions, it requires four weeks, less or more, to bring the malady forward to its stage of obvious symptoms and death. Sixth. — The sascej^tihility of different kinds of cattle. The fact seems well established that well bred and full fleshed cattle are extremely susceptible to the operation of the contagium, and that in them its highest rate of mortality is produced. The fact also is indisputable that in the herds that have the misfortune to bring the disease or contagium from Texas, only a small percentage become fatally sick; but in such herds many that do not die of the disease linger many weeks in an emaciated and diseased condition. Seventh. — Acclimatization and insusceptibility to the cause of the disease. This kind of security seems to be enjoyed only by cattle that have been bred or pastured south of the Osage and Arkansas rivers; but whether this partial security against the malady is due to the peculiarities of wild cattle, or to a gradually acquired physiological power to resist the fatal operation of the primary cause of the disease while grazing at its very sources, does not appear to be proved. Eighth. — Is the disease due to crowding and abuses of cattle 9 Plainly, it does not originate from such causes; but there is evi- dence that the Texas cattle that are crowded upon the "boiler deck " of the Mississippi steamboats, and subjected to thirst and fasting on the voyage up the river, have thus far been themselves the greatest sufferers bj disease, and have proved to be the most frequent carriers of the cause which last summer destroyed native herds in Illinois and Indiana. Nijsth. — 8uscejptibility of other animals than those of the bovine sjpedes to the disease. The fact seems to be well established that several kinds of herbiverous animal do suffer and die from the disease. Tenth. — Is the disease of cryptogamic origin ? With the amount and kind of evidence now in our possession, it seems probable that this malady owes its origin to a species of fungus parasite which has now been demonstrated to infest infected cattle; and that this conclusion rests upon other and much stronger reasons than that such a parasite simply is found in the blood and bile. It also seems highly probable that the actual contagium, or means by which the disease is repropagated by cattle, will ultimately be demonstrated to depend upon this minute spore-growth {micro- [Ag.] 74 1170 Annual Report of New York coccus matter, of Professor Hallier), which is found in the diseased cattle and upon the higher stages of the development when depos- ited with the excremental droppings upon the soil, etc. And, that ultimately it may, and probably will be discovered, that the native habitat and source of this parasite is in limited districts of country south of Missouri, Kansas and Arkansas; and that it is a parasite of the indigenous herbage of those districts. Upon all these points the evidence is cumulative, harmonious and logical; yet, in the more advanced state of knowledge concerning the causation of this and other infectious diseases, it may be found that this or some other essential attribute of the disease and the conta- gium is only an essential factor, the presence of which, with other morbid and unhealthful conditions, insures the production and fatal operations of the malady. Finally, in regard to this exact kind of discrimination concerning the nature and destructive operation of the propagating cause of pestilential diseases, the facts that have been demonstrated concerning the Texas cattle disease add very largely to a kind of knowledge which is of the highest importance to sanitary science and its protective applications in the human family and to the useful animals which the Creator has given to man. ELISHA HAEKIS. PLATE n. Clw*rUtaViinH«nThiwstn\ : PLATE HI SH(!tioii;; {}[' the Ab^ in i'{\\\\/ri\f^o.op .■!un-K-rMV.mBfTLtluTv.s<.w\'^c.nR PLATE A^ AiJ]j«ararLce of 3^''' and 4'J^utumachs, in thetegimiing of die acme stage Sec Plata 1 .Fiq.Z. CK.iik-s Vm> Bcutlvuv.'.ci PI. lit. \ iVloi K ptMlioiiol \l)Oiiiaoiim /.'. lu, /,/,',■ /.■>/ J,ifJi.C\ii/i JtriilJii/l/Te/i ,( Xn/is, .l//„iiit/ ,X )' PLATE VI. -vbomas-um. Charles Vaj\,BpntKiiysei\ fk ^'i- t'LATEA-H Erosions m.Lhe AboiTLcisum. Plate VflJ Fi^ 1 Mucous TJiernliraiie of rectum Accidental ulcer on lip. ff.Jlc/Ur,' /e,, Xi/Ji.f.\'ali //rjiMiyl/sm -f Smix .1//,,,/,,/ . .Y. }'. Plaip. IX. y^. i{o/,/c-,- /^v/ fJtJi .Cl'ttii ttfiii/Mi/Sfii X Snris;/U/injii/,.Y.y. :i^»* t Plate X MuccMis ineiiil:iTane of bladder I r * «*:;.:■ I'a^,.^' 3^ V /?. MaA/r,- /'v/ ,ATE XI Appearances of Duodenum, dn d Rectuin piuATE xn. Fii^.2 R. KbeWer.feclr., Folds of Ab omasum, (Texas Steers.) CJifirlesVan Bemto^eri f*. Sons. PLATE Xni Plate XIV. /.'. /u^/,/r,- /,r (j urtesiine ///A .c'.i '/if J /if/it/ttjt/A-f/t «f S'tt/is, .-i/zj/t/tt/ , . r )' PLATE :w Pig. 4. Sections of Mucous Membrane, nharles V.ui Bemhx^iSi ..r-l-^.'infi-r.r., rl;ffo- HLATK XVI Liver and Gall Bladder, (weighl,18'^lbs.j ChailesVan Beti*viys6Ti & Sojis. PLATE XVn. View of Liver layi! .; i . (waxy, f cLtty,-weigte.2jl:lj)S) RiCoeWei.fecii PLATE XVin . CKarlea VanBentWyseriA. Sw M'spleen«iste5«te, Fig,2, Section of surface ofsameweduced. Fi^-.B. Section of Mp PLATE XK Kidney laid open, (haematoidme stain . and fat .) R.Koehler, fecit Ch-nrlefiV<>n Benthuysen A Sons R.KoeMer, feat Gh-iilesVcUiBenihT^en Sms Fig.l. Kidney (same animal as pla.te 17.) Fig. 2. Kidney of convalescent, (one week convalescent.) PLATE XXI. Fig.l. Secti.011 Ui ryiuiii; ijuiiiuu ui AouiiLdSiiiu (.sevp.ial weeks c(niVdi.e;:c'("iT) h .rl«::V.mBct,Umys.jnir jb'i^'.^ ottoliun of Rectum. i,",pp. plate, 17.) PLATE XXI. Fi^; 1 Gection oi Pyloric; poiuoii or Aboraasuro. (sweral weete conv.-i in;;, ■.mT 'i . .il.j;jV.mBem1\uysoii& ¥i^ Z oBotiurrof Rectum, ^-^ y\l)(iii].i.siiiii one wcciv coi ivnlcscci il f.ll/,'}:\t,il liriil/itil/.yil .< S,r,>ii/..\ i: PLATE XXm. "t- J leotion of Hrcle, Liver and Spleen, m Ox several days after acute sta^e. ChorlesVanBentlixiyseii^. Sans. •. w ^ v- o c o _l ^ C D QQ „ ^ UJ 1^ > c 1- '" < c Z > z i H tl _l < UJ c z c < (X Cf s or O ^ q: a U- c z C LU 4> J C 0. l> CO ^ a> ^ Urine and Liver. 3 4 l.Tth. C.YaE-Be-nth-aysen&SoTis .^bariy .TJ T PleticuiiiiTi of Bile -ducts 4-^a I': Van L'",[,v i.v;"--r, .k 3oiif , All Tiny , "N Y Liver sLiad Kidney. 6 Litli . C , Var^ B enth-ays en & S ons , jM "b any , N , Y Spleen of disease Sc convalescence 8 Litii. C.YaaBenthuysen&Sons , -Albany .U Y Micrococcus o£ Bile 10 n Litli . C . Yan- B enthuys enlkS oris , Aih any ,Ji X Haematoidme Fig, 12 Fig.l3. Liih., CYanBenthuysen&SoTis , Alt any ,15. X PLATE XXXII. J- , Zitho^raphed frovx. Sketches of ConiothecCum hy E . HalLier . ''">.-.•», «lVf?:.d o ,oo No. 5. OO No. 2 No. 5. g <^^ '.'."■^ d>^ No.6.(a No. 6/^1,; '^^- i . **^': m^ .. * ^' ^:^s%: O- ::.:.. W^. --f^ mh ±J^^^'