mtI)fCttpoflfttjg(jrk CoUefie ot ^fjpsiicianfi anb ^urgeoni 7^ S^'T^^ (. Digitized by tine Internet Archive in 2010 witii funding from Open Knowledge Commons http://www.archive.org/details/diseaseofinebrieOOamer THE DISEASE OF INEBRIETY FROM ALCOHOL, OPIUM AND OTHER NARCOTIC DRUGS, ITS ETIOLOGY, PATHOLOGY, TREATMENT AND MEDICO-LEGAL RELATIONS. ARRANGED AND COMPILED BY THE AMERICAN ASSOCIATION FOR THE STUDY AND CURE OF INEBRIETY. NEW YORK: E. B. TREAT & COMPANY, 241-24^ WEST 23D STREET. 1899. $2.00, n«t. CC)PYR]GHT, 1893, By the American Association FOR THE Study and Cure of Inebriety- o Cir: DEDICATED TO THE MEMORY OF DR. J. EDWARD TURNER, THE PROJECTOR AND FOUNDER OF THE FIRST INEBRIATE ASYLUM IN THE WORLD, AT BINGHAMPTON, NEW YORK. ALSO TO THE MEMORY OF THOSE PIONEERS, NOW PASSED AWAY, WHO FAR IN ADVANCE OF THEIR TIMES ORGANIZED THE FIRST SCIEN- TIFIC SOCIETY FOR THE STUDY AND CURE OF INEBRIETY : DRS. JOSEPH PARRISH. THEODORE L. MASON, WIL- LARD PARKER, DANIEL DODGE, JOHN WILLETTS, AND OTHERS. THIS VOLUME IS OFFERED AS A SLIGHT TRIBUTE TO THEIR SUPERIOR DISCERNMENT, AND PRAC- TICAL RECOGNITION OF THE GREAT ONCOM- ING TRUTHS OF INEBRIETY. INTRODUCTION. In 1870 the American Association for the Study and cure of Inebriety was organized in New York City. Its members were composed of physicians connected with asylums for Inebriates and others interested in the scientific study of the drink problem. The following statements were adopted as representing the principles and purposes of the Association : 1. Inebriety is a disease. 2. It is curable as other diseases are. 3. The constitutional tendency to this disease may be either inherited or acquired ; but the disease is often in- duced by the habitual use of alcohol or other narcotic sub- stances. 4. Alcohol has its place in the arts and sciences, but as a medicine it is classed among the poisons, and its internal use is always more or less dangerous, and should be pre- scribed with great caution. 5. All methods hitherto employed for the treatment of inebriety that have not recognized the disordered physical condition caused by alcohol, opium, or other narcotics, have proved inadequate in its cure ; hence the establishment of Hospitals for the special treatment of inebriety, in wliicli such conditions are recognized, becomes a positive need of the age. 6. In view of these facts, and the increased success of the VI INTRODUCTION. treatment in inebriate asylums, this Association urges that every large city should have its local and temporary hospital for both the reception and care of inebriates ; and that every State should have hospitals for their more permanent detention and treatment. 7. Facts and experience indicate clearly that it is the duty of the civil authorities to recognize inebriety as a dis- ease, and to provide means in hospitals and asylums for its scientific treatment, in place of the penal methods by fines and imprisonment hitherto in use, with all its attendant evils. 8. Finally, the officers of such hospitals and asylums should have ample legal power of control over their patients, and authority to retain them a sufficient length of time for their permanent cure. For twenty-two years this association has held annual and semi-annual meetings in which a large number of papers have been presented, read and discussed. In the first seven years, six volumes of transactions were issued, then a society journal was established as the official organ of the association. This was called the Quarterly Journal of Inebriety, which has been published since 1877; the special work of this journal has been to gather and group the scientific literature of this subject and make it available for future study. In addition to this literature, many members of this association have published volumes on this subject. Of these may be mentioned : " Alcoholic Inebriety" by the late Dr. Joseph Parrish, President of the Association ; ** Metho- mania" by Dr. Albert Day, the present President ; ^^ Inebri- is>n,*' by Dr. T. L. Wright, a member of the Association ; "Inebriety," by Dr. Norman Kerr, of London, an honorary member ; " Alcoholism," by M. Magnan, an honorary member, of France ; " The Manifestations of Alcoholism," by Dr. Lentz, of Brussels, an honorary member ; " Alcoholism as a Malady^* by Dr. A. Baer, of Berlin, also an honorary member. INTEODUCTION. Vll III both this country and Europe, a large number of valuable papers and monographs on this topic, have appeared. Among the most prominent who have written on this subject may be mentioned Drs. Mason, Crothers, Mattison, Mann, Hughes, Searcy, Wright, Davis, Shepard, Morris, Day and many others. Abroad, Drs. Peddie, Kerr, Clouston, Carpenter, Ridge, Richardson and many of the most eminent physicians and medical teachers of Europe. A large part of these writings have been published in \.\ic Journal of Inebriety, together with the discussions and criticisms which have grown out of them. This literature has been copied into medical and other journals and become the subject of lectures, sermons and works on temperance ; but in many cases the original ideas have been changed and modified to such an extent as to be unrecognized. As a result, the most confusing uncertainty and conflict of opinion exists concerning the scientific study of inebriety and its maladies. Recently, this subject has attracted renewed attention, growing out of the empiric assumptions of specific reme- dies for its cure. Following this, an increasing demand has appeared for some authoritative grouping of the studies of scientific men in this field, and suggested the value of a volume comprising some of the best papers which have been published in the journal. In accordance with this, the following resolution was unanimously adopted at the November meeting of the Asso- ciation for the Study and Cure of Inebriety. " Whereas, In view of the fact that the demand for copies of the Journal of Inebriety containing special studies, mono- graphs and papers on distinct phases of inebriety is steadily increasing, together with constant inquiry from physicians for facts, statistics and conclusions relating to the disease of inebriety; Vlll INTEODUCTION. " Therefore^ resolved^ that the secretary be authorized to prepare a volume, wliich shall contain the most reliable conclusions and studies of eminent authorities on all phases of the disease of inebriety up to the present time ;" ^^ Resolved, that the secretary, with the publication com- mittee, make all arrangements for the printing and issuing of said volume at the earliest possible moment. This volume is in conformity with this resolution, and simply aims to give the reader many of the best and most suggestive studies of this subject which have appeared. More prominence has been given to heredity, treatment and medico-legal relations, because these phases are dis- puted and the subject of confusing controversy. The fact of disease in inebriety has passed beyond question and is practically settled, hence all moral theories or discussions are of little or no value from a scientific point of view. These various studies are not presented as exhaustive, but rather as outlines suggesting wide stretches of the unknown, inviting the reader to take up this subject and extend its frontiers far in advance of the present. It will be apparent to all that the scientific study of in- ebriety is yet in its infancy, and no student or volume can do more than give a general view of the most probable facts which appear to be sustained by the strongest evidence available up to this time. This volume is intended to represent the work of the Association for the Study and Cure of Inebriety and the cliaracter of the papers and discussions which have appeared in its journal. For over a quarter of a century, this association has studied exclusively the scientific side oi inebriety, and although it has not attracted much attention and is practi- cally unknown, it has been a great silent power, crystalliz- ing and marshalling the many facts constantly appearing from a knowledge of these cases. INTRODUCTION. IX The drink malady, its causes, cure and prevention, are practically an unoccupied field of medicine, and this work is offered as a guide and stimulus to farther study in this direction. These selections have been gathered from over five thousand pages of printed matter, published in the journal iiiid transactions, and are from papers which have not appeared elsewhere and hence will be new to most pliysi- cians. It will be evident to tlie reader that while the facts are very numerous and startling, and fully sustain the principles of the association, tliey are not yet sufficiently studied and generalized to be accepted as absolute truths. Tills volume brings the subject up to the frontier lines, and suggests that the possibility of restoring the inebriate and stamping out inebriety, is onlylimited by our want of knowledge of the laws and means to accomplish this end. It also suggests that a solution of this great problem of the forces and sources which develop the armies of the inebri- ates or halt and disband them, must be along the line of accurately observed facts and their meaning. The purpose of this work will be accomplished, if, in any way, it shall help on this pioneer work. T. D. Crothers, Secretary. Hartford, Conn. March, 1893. CONTENTS. CHAPTER I. PAGE Early history of the Theory of Disease in Inebriety. — Opinions and Statements of authors and writers in Europe and America 17 CHAPTER n. History of disease theory in modern times, — Dr. Turner, New York State Inebriate Asylum. — American Association for the Study and Cure of Inebriety. — Journal of Inebriety ^ etc 22 CHAPTER III. Different forms of Inebriety. — Classes of Inebriates.... 27 CHAPTER IV. Dipsomania and its varieties and manifestations 29 CHAPTER V. Some phases of the philosophy and etiology of Inebri- ety. — The higher ranges of causes 39 CHAPTER VI. Inebriate diathesis, its conditions and relations 47 CHAPTER VII. General and predisposing causes described 55 X'l CONTENTS. CHAPTER VIII. PAGE Special exciting causes. — Traumatism nnd injury 66 CHAPTER IX. Special causes continued, Adversity, Sunstroke, Heat, and other causes 79 CHAPTER X. Inebriety in America. — Some of its peculiarities, etc. .. 90 CHAPTER XI. Prevalence and mortality of Inebriety. — Fatality in epi- demics, etc 100 CHAPTER XII. Relation between Inebriety and Consumption, etc., etc 103 CHAPTER XIII. Effects of alcohol and beer on mental functions, etc. .. 113 CHAPTER XIV. Climatic periods and diagnosis of Inebriety. — Study of social statistics 118 CHAPTER XV. Delirium tremens and associated conditions 131 CHAPTER XVI. General facts of heredity and predisposing conditions. 145 CHAPTER XVII. Heredity continued, views of foreign authors 155 CHAPTER XVIII. Statistics of heredity and other considerations 161 CONTENTS. XI U CHAPTER XIX. PAGE Pathology and general considerations of the nature of Inebriety 173 CHAPTER XX. Some of the pathological changes common to all cases of Inebriety 185 CHAPTER XXI Treatment, some general considerations of the nature and plan 197 CHAPTER XXII. Inebriate Asylums and their nature and work 215 CHAPTER XXIII. Hygiene. — Hot air and other methods of treatment. . . 227 CHAPTER XXIV. Duty of the State in the care and treatment of Inebri- ates 239 CHAPTER XXV. Special care of Pauper Inebriates in cities and towns.. 251 CHAPTER XXVI. Some medico-legal considerations concerning Inebriety. 265 CHAPTER XXVII. Medico-legal questions continued, rulings of judges and the law 277 CHAPTER XXVIII. General questions of irresponsibility in Inebriety 285 XIV CONTENTS. CHAPTER XXIX. PAGE Some special forms of irresponsibility, trance, etc 297 CHAPTER XXX. Practical relations of inebriety, coma, and brain dis- ease 309 CHAPTER XXXI. Opium Inebriety . — Its nature and character 317 CHAPTER XXXII. Opium inebriety continued. — Its special treatment..,. 329 CHAPTER XXXIII. Ether Inebriety. — Its origin and consequence 347 CHAPTER XXXIV. Cocaine Inebriety 357 CHAPTER XXXV. Chloroform Inebriety 363 CHAPTER XXXVI. Inebriety from coffee and tea, and its effects 369 CHAPTER XXXVII On the psychosis caused by nicotine 377 CHAPTER XXXVIII. Eau de Cologne drinking. — Arsenic and ginger inebri- ety 3^3 DISEASES OF INEBRIETY. CHAPTER I. EARLY HISTORY OF DISEASE THEORY. It is a curious fact that inebriety was recognized as a disease long before insanity was thought to be othet* than spiritual madness and a possession of the devil. The fact has escaped the attention of persons who assert that inebriety is always a vice, and the disease theory is only an extrava- grant view of enthusiasts, peculiar to our times. For over a century, the disease of insanity was denied and contested. Inebriety is passing the same ordeal of ignorant opposition and criticism, notwithstanding it has been recognized by a majority of the leading physicians of the world to-day. The following outlines of the early history of inebri- ety will show that this is not a mere theory of our times, but a great truth, outlined and foreshadowed by many of tlie leading physicians and philosophers of the past. This disease was hinted at in an early age of the world, and is by no means a modern idea. On an old papyrus found in one of the tombs of Egypt> dating back to a very ancient period, was the following significant passage, referring to an inebriate who had failed to keep sober . 17 18 DISEASES OF INEBRIETY. " Thou art like an oar started from its place, which is unmanageable every way ; thou art like a shrine without its God, like a house without provisions, whose walls are found shaky." Many of the sculptures of Thebes and Egypt exhibit inebriates in the act of receiving physical treatment from their slaves, such as purgatives, rubbings or applications to the head and spine, Heroditus, five centuries before the Christian era, wrote, " that drunkenness showed that both the body and soul were sick." Diodorus and Plutarch assert " that drink madness is an affection of the body which hath destroyed many kings and noble people." Many of tlie Greek philosophers recognized the physical character of inebriety and the hereditary influence or tend- encies which were transmitted to the next generation. Laws were enacted forbidding women to use wine, and young boys were restricted. Frequent reference is made to the madness which souglit solace in wine and spirits. Such cases are called and urged to give more diligent care to their bodies, a distinct hint of the physical origin of inebriety. In the first century of the Christian era, St. John Clirysostom urged that inebriety was a disease like dys- pepsia, and illustrated his meaning by many quaint reason- ings. This was the first clear, distinctive recognization of the disease, which had been hinted at long before. In the next century, Ulpian, the Roman jurist, referred to the irresponsible character of inebriates, and the necessity of treating them as sick men. His views were embodied in some laws, which referred more distinctly to the physical nature and treatment of inebriety. Many of the early and later writers of Roman civiliza- tion contain references to drunkenness as a bodily disorder, not controllable beyond a certain point, which resulted in veritable madness. Nothing more was heard of this theory until the thirteenth century, when one of the Kings of EAELT HISTORY OF DISEASE THEOKY. 19 Spain enacted laws fully recognizing inebriety as a disease, lessening the punishment of crime committed when under the influence of spirits. One of the laws provided, that when murder was committed during intoxication, the death penalty should be remitted, and the prisoner be banished to some island for a period of not less than six years. In the sixteenth century the penal codes of France and many of the German States contained enactments which recognized the disease character of inebriety. All punishment for crime committed during this State varied according to the conditions of the prisoner at the time. Drunkenness, continued beyond a certain point, was regarded as a condition of insanity and irresponsibility. In many of the medical writings of these ages, drunken- ness and madness were mentioned as synonyms, and curious reflections on the nature and treatment of the evil are detailed. In 1747, Condillac, a French philosopher, wrote express- ing clear views of the disease of inebriety, also that the State should recognize and provide means for its treatment. He asserted that the impulse to drink was like insanity, an affection of the brain, which could not be reached by law or religion. Dr. Benjamin Rush, of Philadelphia, in 1790, set forth the same theory, supported by a long train of reasoning. To him belongs the honor of first elaborating this sub- ject and outlining what has been accepted half a century after. In two essays, entitled, " The influences of physical causes upon moral faculties," and "An inquiry into the effects of ardent spirits upon the human body and mind," he described the disease of inebriety, dividing it into acute and chronic forms, giving many of the causes, of which heredity was prominent, also urging that special measures be taken in the treatment, which should be in a hospital for this pur- 20 DISEASES OF INEBRIETY. pose. Up to tliis time these views were clear and distinct- ive, althougli not published until 1809. They were entirely independent of all previous observations. In 1802, Dr. Cabanis, of Paris, wrote fully indorsing the views of Condillac, that inebriety, like insanity, was a disease which should be studied, and that it was a distinct form of mental disorder, needing medical care and treatment. Pro- fessor Plainer, of Leipsig, published a paper in 1809 (the same year Rush's writings appeared), affirming that ine- briety was like an insane impulse and a form of insanity which should receive medical care and be studied by the aid of science. In 1817, Salvator, of Moscow, a physician of some emin- ence, published a pamphlet called " Ebriosity, its pathology and treatment." He divided drunkenness into two forms, intermittent and remittent, and urged that they be treated by physical means. Esquirol, in 1818, described a condition of the nervous system in which inebriety was sure to follow. In 1822, Buhl Cramner, a distinguished physician of Berlin, wrote a small book defining inebriety as a state of irritation of the brain and nervous system, to be cured by physical means because it was purely of physical origin. In Europe the writings of these four men, Platner, Sal- vator, Esquirol and Cramner, placed the subject on a scien- tific basis, paving the way for a wider and more thorough study. Although Dr. Rush had written on the general subject more definitely than the others, his writings were practically unknown. In 1830, a committee of the Connecticut State Medical Society, appointed the year before to report on the necessity of an asylum for the medical care and treatment of inebri- ates, recommended in an elaborate essay that it was expedi- ent to establish an asylum for the cure of inebriates. This report, written by Dr. Todd, the superintendent of EARLY HISTOKY OF DISEASE THEORY. 21 the insane asylum, strongly urged the recognition of the disease of inebriety and its curability by physical means. Tliis report, wliich may be found in the Transactions of the Conn. State Medical Society, was a remarkable concep- tion of the subject, far beyond the current opinions of that time, only now beginning to be recognized. In 1833, Dr. Woodard, of Worcester, Mass., urged that inebriety was a disease, and curable as other diseases in asylums for this purpose. This attracted attention and was endorsed by many. In 1839, Dr. Roesch, of Tubingen, in a volume on spirituous liquors, urged that inebriety be considered a disease. He elaborated the idea and pointed out the errors of other authors at some length. Dr. Nasse, of Bonn, followed, urging the same view. From this date, the literature has grown rapidly, especi- ally in this country. The opinions and writings of Ameri- can physicians on this subject are now widely sought for in Europe. The English Lunacy Commission, in 1844, urged that inebriates should be regarded as insane, sent to asylums for treatment, and not punished as before. Many other writers timidly followed these advanced theories and, when stoutly opposed, compromised by admit- ting a state of half disease and half vice. CHAPTER IT. HISTORY OF DISEASE THEORY IN MODERN TIMES. The Washingtonian temperance revival, of 1840, seemed to have cleared away man}'- of the old theories and prejudices, and gave clearer conceptions of the real nature and charac- ter of inebriety. The sudden and intense projection of the moral side of inebriety reacted when this reform wave died away, but it had served to fuse and mobilize the tide of oncoming truth, outlined for a long time in frequent statements of the disease of inebriety. The first practical demonstration of this began in a lodging-house for in- ebriates, opened in 1845, at Boston, Mass., called the Wash- ingtonian Hall. This recognized, in a crude way, the phys- ical disabilities of inebriates, and souglit to remove them by physical means. This was tiie first embrio asylum of the world, which has grown into the Washingtonian Home of the present da3\ While physicians and writers were repeating the theories of the possibility of disease of inebriety, Dr. J. Edward Turner, a Maine physician, came forward as the great pion- eer to vitalize and show the practical value of the truth that inebriety was a disease, and curable. In 1846, Dr. Turner became interested in this work from an ineffectual effort to save an early friend who was an inebriate. He recognized the nature of the disease of inebriety and the need of hospital treatment, and began an enthusiastic agitation of the subject. After eight years of most persistent effort, in the face of great opposition, he succeeded in enlisting the attention of many eminent medi- 23 HISTORY OF DISEASE THEORY IN MODERN TIMES 23 cal men, and in forming a company to build an Inebriate Hospital, witli the late famous surgeon, Dr. Valentine Mott, as president. Laws were passed to give power to hold inmates, a charter was granted, and nearly fifty thousand dollars subscribed for tlie grounds and building. Ten years later, in 1864, a magnificent building was completed and opened for patients, at Binghampton, N. Y., the pioneer hospital of the world. Later, a fire destroyed part of the building, which was soon after rebuilt. Then the board of trustees became involved in a controversy with the founder, Dr. Turner, resulting in his retirement, and placing the hospital in the care of the State. Passing into the manage- ment of politicians, its history was a series of misfortunes, until finally it was changed into a chronic insane asylum. Thus Dr. Turner, the founder, who had conceived and built this hospital, giving over a quarter of a century of time and effort, and his own personal fortune, shared the fate of all reformers and benefactors of the world, in the obloquy and disgrace of being driven away from the creation of his own genius. The New York State Inebriate Asylum was the first institution of the kind ever organized. After fourteen years of a most extraordinary history, it was closed and converted into an insane asylum. The same old battle has been waged around and about this institution with which every new truth of science has had to contend. Bitter skeptics and foolish enthusiasts have rushed to conclusions in regard to his work, which could only be determined by a century of accurate study and observation. Literally, this pioneer asylum has been the great " On to Richmond" movement, checked by a Bull Run disaster. During the fourteen years of its existence, two thousand three hundred and forty-four inebriates weie under treatment. A vast majority of these were the most chronic cases. The enthusiasm wliich at first centered about Binghamp- ton Hospital reacted, and the moralists and temperance 24 DISEASES OF INEBRIETY. advocates, who from tlie first liad opposed tliis movement as an " infidel work " to diminish human responsibility, used every means to spread the idea of failure and condemn other efforts in this direction. But a great fact had been recognized, and its practical character had taken deep root in the public mind. The birth of the Binghampton Hospital was followed by the organization of over a dozen different hospitals for this work in different parts of tlie country, some of which are still in existence, doing grand work. Notwithstanding the misfortunes of the first hospital and its founder, a large number of similar places have been organized and managed with success. As in all new enter- prises, many of these hospitals must suffer from non-expert management, and be organized on some theory of the nature and treatment of inebriety not founded in correct study and experience. After a time they are abandoned or changed to homes for nervous and insane cases. Over fifty different hospitals for inebriates have been established in America. More tlian thirty of this number are in suc- cessful operation ; the others have changed into insane asylums, water-cures, etc. Tiiree large buildings or insti- tutions are practically " faith cures," wiiere all physical remedies and means are ignored. Several asylums are called homes for nervous people, to conceal the real cause, and thus protect the patients from the supposed stigma of inebriety. Others are literally lodging-liouses, where the inmates can remain a few days and recover from the effects of spirits. Several places make a specialty of opium cases ; in some the treatment is often empirical. In only a few of these hospitals is inebriety studied and treated on a scien- tific basis. The others are passing through the ordeal of "elimination and survival of the fittest," incident to every new advance of science. In many of the States large pub- lic hospitals are projected, and are awaiting pecuniary aid from the State or from other sources. Most of the inebriate hospitals in America are private HISTORY OF DISEASE THEORY IN MODERN TIMES. 25 and corporate organizations, wliich receive, from time to time, State aid. Some of them have endowments, such as free beds, or incomes from estates, or are given so much of tlie license money. Others depend upon the income from patients, private donation, and charities generally. Very few paupers or indigent poor are received in any of these hospitals. This class appear in the "lodging" and " faith- cure " places. The State of Connecticut has projected a workhouse hospital for the criminal class of these cases, where the commitment is for three years, but want of State aid has prevented practical work so far. In three other States similar projects for the pauper inebriates have been organized, but for various reasons have not gone into oper- ation. In Europe, over sixty hospitals for the physical care and treatment of inebriates are in active operation to-day. There are two in Australia, one in China, two in India, one in Ceylon, three in Africa, and one in Mexico. While these institutions vary widely in plan and methods, the central idea is the physical treatment of the inebriate and his malady. The literature of this subject has grown to enormous proportions, principally in papers, lectures and pamphlets. The exact scientific study of inebriety has revealed facts and conclusions which have aroused bitter controversy from those who should have been first to welcome its truths. A large number of so-called reformers have been from the first denouncers of the disease theory, but unwittingly they have greatly helped on the work by controversy and agitation. In 1870, an association was formed of persons who were connected with inebriate asylums, or interested in the subject, called' the American Association for the Study and Cure of Inebriates. This Association has since met yearly and semi-yearly ; its papers and transactions comprise the first permanent literature on this subject. In 1877, the Journal of Inebriety was issued as the organ of this association, and from that time has been the medium through which most 26 DISEASES OF INEBRIETY. of the literature of the subject from America has been pre- sented. Inebriety, and its curability in special hospitals, has been the cardinal principle of this Association, which it has demonstrated and maintained with increasing vigor. Discussing exclusively the physical side of this subject, amid difficulties which only pioneers in a new field have to contend with, tlie foundation of a scientific literature has been laid which will be historic to future students of this subject. This Association and its journal are great silent powers, crystallizing and marshaling the many facts con- stantl}'^ appearing from a study of tliese cases. Already sev- eral members of this Association liave publislied works on inebriety that mark the beginning of a " new era," and have given great impetus to its scientific study. In 1884, a similar society was formed in England, called the Society for the study and cure of Inebriety. Similar societies have been formed in France, Switzerland, Germany and Sweden. In 1887, an International Congress was held in London for the discussion of the disease of inebriety. Delegates from all the world were present. Numerous committees, scientific and legislative, have made elaborative reports on the disease of inebriety and the means and measures for its prevention and treatment. CHAPTER III. INEBRIETY : ITS CLASSIFICATION AND FORMS. This term more accurate!}' represents the general phenomena called diunkenness tlian any other. There are two great classes, which may be designated Inebriates and Dipsomaniacs. The first class, when studied collectively, seem to divide into several classes from different causes witli different symptoms and termination. One of these classes are the accidental idebriates, persons whose use of spirits are depend- ent entirely on external conditions and environment. They seem to possess a high degree of brain and nerve instability, and have small resisting power, or capacity to adapt themselves to new surroundings and conditions of life, and retain any fixed individuality. Such persons drink or abstain according to the company they are associated with. They are enthusiastic temperance reformers, or abject drunkards, from the mere contagion of surround- ings. In a prohibition community, they are models of sobriety, or types of the lowest drinkers where spirits are free. Their progress and future turn altogether on environment. A second class of these accidental inebriates are con- trolled solely by functional disturbances of the body. Spirits are never used except when some derangement of tlie organism occurs. Attacks of indigestion, chills, over- work, and all forms of minor strains or drains, lead up quickly to the use of spirits, without reason or premedita- tion. After the sedative action of alcohol has taken place a 27 28 DISEASES OF INEBRIETY. few times, the internal resisting force is permanently broken up and tlie person drinks ever after. A second group may be called emotional inebriates. They belong to that class who are always on the borders of hysteria, with feeble and unstable will. Wayward, selfish, fitful, uncertain, out of harmony with every relation of life ; all the time suffering from a constitutional unrest, and emotional struggles to attain the impossible. Spirits afford relief for this physical state, and are alternately used and abandoned until death or insanity comes on. Another class, called solitaiy inebriates, use spirits only at night or alone, and seem morbidly sensitive to conceal this fact. They always deny all use of spirits, and display great cunning and tact to cover up this condition. Tiieir drink- ing seems often to be under control of the morbid reason, and is checked at certain times, and is limited b)' con- ditions and circumstances. These are the most interesting of all cases, and often appear in persons who occupy responsible positions, and involve very important ques- tions of business and science. . A large class of inebriates, appearing in lower levels of life, are found to be literally constitutional paupers, who through heredity and environment are switched off on the side-track of dissolution. They may be termed the pauper inebriates, and are persons with special unfitness for healthy life, who are by the higher processes of nature crowded out in the race struggle. Inebriety is simply another symptom of this condition. The subsidence of the drink craze is followed by other degrees of degener- ation. Criminality, pauperism, prostitution, are all allied conditions. Many other sub-classes of inebriety are found, but they all date from some condition of brain and nerve degeneration, and although the symptoms may vary, the line of progress and growth are practically the same. CHAPTER IV. DIPSOMANIA : ITS HISTORY AND RELATION. Dipsomania is a term used to designate a large class of inebriates, in which the drink impulse comes on suddenly and after a time dies out, and is succeeded by a free inter- val. This has been truly termed a neurosis, which is prac- tically another branch of the same family of epileptics, insane hysterias and paranoic. There are three principal forms : First, the acute, which is not very common, wliere the drink craze comes on sud- denly from hemorrhage sunstroke ; and also convalescence from fevers, excessive strains, as continuous overwork, with mental care and excitement, and also severe drains of the nerve energy, exhaustion and other causes. This variety seems to resemble an attack of mania in its violence and uncontrollability, and good evidence of dipso- mania being an insanity and requiring careful watching and treatment. Th^ periodic is a more common variety. By some authors it is considered the most common form, but in our expe- rience the chronic is more frequent. In this variety are classed those patients who have periodic attacks of drinking lasting for a long or sliort period. In some patients the attack comes on suddenly. That is to say, they take to drinking laige quantities of alcoholic fluids without any premonitory symptom. But more often there is noticed an alteration in character and temper that fore- warns those who have anything to do with the patient. In the case of a married man, the wife can almost always tell 29 30 DISEASES OF INEBRIETY. when an attack is coming on. The length of these attacks vary greatly, more especially according to the duration of the disease in the patient. In the early history of tlie disease, the drinking bouts often last from one to three weeks, and during that time the patient is constantly drinking. When he cannot get the quantities of liquor that he requiries outside, he takes to diinking in his own rooms or house. Nothing will stop him. If his friends or servants try to get him to leave off, he storms and rages, and terrifies tliem into submission to his ways and wants. His excuse for drinking is always that he is excessively weak and nervous and requires support, and that it is abso- lutely necessary for his life that he should have stimulants. His appetite soon disappears, and he only makes vain efforts to partake of any food tliat is brought to him. Great sleeplessness and restlessness comes on, and in fact, the patient is often on the verge of delirium tremens when the disease abates either gradually or suddenly, and he gets fairly well. When it ends suddenly, it is from an attack of acute or subacute gastritis, for which he requires and seeks medical aid. The craving for drink having also disap- peared, he willingly submits to medical direction, and under judicious treatment, recovers. When the attacks go off gradually there are less severe gastric symptoms, and the craving having become less, tliere is a diminution in the gastric and nervous troubles. After patients have lived for several years with these periodical attacks, the duration of attack diminishes in length, and they increase in frequency ; the cause of this being chiefly due to the effects on the gastric system. The stomach much sooner resents the large quantities of alcohol put into it, and consequently the drinking fits are cut short by attacks of gastritis, and often also enteritis. But from the attack being shoiler, the interval of diminution in drink- ing also becomes shorter, so that tlie patient gradually goes on from bad to worse. Once the drinking fit passes ofi, the DIPSOMANIA : ITS HISTORY AND RELATION. 31 patient generally expresses great horror and grief at his propensity and the effects it produces, and will make all sorts of promises to abstain altogether from alcholic drinks. If the case is not a severe one, and the moral surroundings of the patient are good, he will often keep his resolution for a long period. But eventually, from some cause, either of social temptation or mental worry, he again breaks out and becomes wholly ungovernable. We have known cases where a man having recovered from a periodic attack would go for a period of from four to eigiit months without drinking any alcoholic liquor, but the first taste of liquor after that abstinence would bring on an attack. A great many cases are called periodic which are really chronic, but with temporary exacerbations, and we will dis- cuss these under the chronic variety. We only include under the periodic those cases where there are complete periods of a natural condition of mind and body ; and in almost all these the patients are either total abstainers or extremely careful and temperate in their habits in the intervals between the drinking fits. The higher tlie moral nature of the patient, the longer are those tranquil intervals, but the lower the moral nature the shorter are those periods. The reason being that a man of high moral nature, either from culture or inherent preception, gets more control over himself and will battle long against the craving when it is coming on, although eventually he gives way not from any fault of his own, but on account of his being the subject of a mental disease entirely beyond his control. On the other hand, a man of low moral standing will never try to keep himself from the temptations that he knows are dangerous for him, and never makes any attempt to stave off the crav- ing, but yields at once. These last are a much more hope- less set of cases to deal with, and are almost always incur- able, and eventually die from accidents or diseases induced by their habits. Dipsomania that comes on from injury to the head is 32 DISEASES OF INEBRIETY. generally of the periodic variety. Blows or falls on the head are followed at a long or short period afterward by periodic attacks of drinking mania. In surgical and medical practice it is well known that similar blows on tlie head are not infrequently followed by epileptic fits, and both these classes of cases, viz., the accession of periodic attacks of dipsomania after injuries, and the periodic attacks of which we have been treating at length above, tend to point to a relation between epilepsy and dipsomania. Just as an injury to the head by producing some alteration in the nerve- centers brings on epilepsy, so do they at other times bring on dipsomania by no doubt causing also some alteration in the nervous tissues. Again, where there is insanity in a family, in the progeny there is a great liability to a repetition of that same condition of the nerve-centers which produces insanity, or else some modification of it, such as epilepsy or dipsomania, for in almost every case of periodic dipso- mania is there to be found a history of nervous affections. There are cases on record of transitions between these two affections. Either an attack of drinking passing off by an epileptic fit, or patients at one time having an attack of epilepsy and at another time an attack of craving for drink. In fact, the two affections are very much alike in many ways. Judging from cases under observation, the periodic variety seems hardly ever to be induced by acquired habits of drinking alcohol, it being almost always the result of strong hereditary tendency to neurosis of some kind. Our object in laying such stress upon the real insanity of dipso- mania is to get its recognition as such by the legislature. We stated just now the difference in effect upon the course of dipsomania caused by the presence of more or less high moral nature in the patient. All those who have studied insanity have come to the conclusion that very often there is a complete absence of the moral nature — patients not having the slightest conception of any moral obligations due to their fellow beings or themselves. DIPSOMANIA : ITS HISTORl AND RELATION. 33 Very frequenth'^, among dipsomanics, is there this complete absence of any morality. It is not often recognized. Friends and acquaintances of the patient accuse him or her of immorality unjustly. For a man cannot be immoral who has no ideas of morality to start with. Many will think such a state of tilings incredible, but it is really not so. Patients suffering from dipsomania often behave very well for a time, but it is only from the effects of habit from the way they have been brought up. They may do what is right, and often appear to go out of their way to do what is right, but if one could get at the root of their actions, it would be found that they were not guided by any moral feeling or sense whatever. Dipsomaniacs show this perversion, or rather, absence of morals, in almost all their dealings with tlieir friends and relations, and it is on this account that the disease is such a scourge to the friends and relatives. The patient will give the most solemn promises not to take any stimu- lant, but the backs of those to whom he has made the promise are no sooner turned than he violates it, either by obtaining the liquor himself or not refusing the first or any temptation that is set before him. They always have a plausible excuse when taxed with their violation of promise. They will also prevaricate most cunningly until the ques- tion is put directly to them. It is curious that in spite of the absence of moral nature they will rarely tell a deliber- ate lie. Some people might think this was due to a vestige of morality, but it is, we think, due simply to a knowledge of their weakness, and to the power exercised by a stronger mind over theirs. This habit of prevarication, of never giving the lie direct, they are cunning enough to bring for- ward as a plea for tlieir being trusted occasionally. But in our opinion, a dipsomaniac can never be trusted. It is not right that he should be led to suppose so, for that would do iiim inevitable harm, as we shall see presently in discussing moral treatment for dipsomania, but at the same time 34 DISEASES OF INEBRIETY. one would never rely on the promises given by a dipso- maniac, more especially if it is in regard to taking any pre- cautions for guarding against his propensity. As regards the recurrence of these periodic attacks, they do not seem to have any regular intervals. In some patients there is a cessation of the drinking propensity for many montlis, in others, only for a few weeks. In the chronic variety we shall have to mention that where periodic exacerbations occur, they often do so at regular intervals, and the length of time is generally a month. In women, where generative functions are periodic, dip- somania, like other varieties of insanity in women, is apt to recur at intervals corresponding to the menstrual periods. The progress, tlien, of periodic dipsomania is generally an increasing frequency of the recurrence of the attacks which may verge into the chronic variety, but as often as not kills the patient before tiiat stage is reached. Among this class, however, are found some who do appear to be cured by careful and judicious treatment during the intervals. The treatment consisting in eleva- ting the moral nature by every possible means, improv- ing the patient's general health, and getting him to employ his mind and body actively. Tiiere is one drug which ought to have extensive trial for treating the periodic attacks. Bromide of potassium is well known to be of great service in reducing the frequency and force of epi- leptic attacks, and seeing the close relationship of dip- somania to epileps}'', it ought to be of use. We have not had the chance of giving it much trial in the periodic varieties, but in the chronic it is of immense service. In those cases where the moral nature is evidently low, weak, or absent, no hope can be held out for cure, and the patients will be an endless source of misery to them- selves and relatives till they die. It is for these cases that a proper law is so much required. During tiie attacks nothing but restraint can keep them from liquor. dipsomania: its history and relation. 35 Men who suffer from periodic attacks live a little longer than those whose attacks are chronic in their nature. Among women the periodic is more common during the whole of the time of the existence of the generative func- tions. Chronic dipsomania in women more often comes on later in life. Chronic Dipsomania. — We are certain that this is the most common form. Those suffering from it generally commence drinking at an early age, usually 17 or 18, and by 30 years of age most of them have died. They die either from the direct effects of the drink they are continually consum- ing, or else from diseases induced by it, such as absolute insanity or diseases of liver artd kidneys. The disease is not generally recognized in the first few years of its course, as the patient's friends and relatives merely suppose him to be living a little too fast, and that he will pull up soon. However, after a few years it is found that he is never really free from the effects of liquor. He is hardly ever really drunk, but is never sober. As we have said before, cham- pagne is the usual drink during the first years of a dipso- maniac's career. When he takes more than enough, it shows its effects by making him very sleepy, and he will lie down at the most unusual times and places, and fall off into an apparent dead sleep, from which it is very difficult to awake him, and if one does so, he usually manifests a disgusting temper, and will curse and swear at his best friends. This sleep does not rest the brain at all, as when they do wake up voluntarily they are by no means refreshed, and immediately have recourse to another stimulant, which generally freshens them up for a short time, but they very soon require re-stimulating. In the early days of their career, these men often go through a large amount of fatigue, and consequently for a time ward off the mental effects of their drinking. They will hunt vigorously and slioot, walking long distances, but the excitement of horse exercise is what they most delight 36 DISEASES OF INEBRIETY. in, as the fatigue enables them to drink large quantities of stimulants without much apparent effect. But after several years the muscular as well as mental system begins to fail. They cannot go through the fatigue they were formerly capable of. Their will also fails. Overnight they will make engagements and promises for the morrow, but the morrow finds them unable to perform their promises, nor have they the will to carry their project out. Every now and then the patient acknowledges that he is drinking himself to death, and he will slacken in and reduce his quantities of stimulants, but never leave off entirely. He very soon, however, resumes his usual large potations. Occasionally he can be induced to go to a home or inebriate asylum for a time, but he never stays very long, and is no sooner out than he resumes his former habits. It is a fearful existence, the constant craving for fluid, and that fluid must have some taste. All dipsoma- niacs have a complete antipathy to water. They will drink anything but water. If they cannot get stimulants they will drink soda-water, lemonade, or ginger-beer, in enor- mous quantities, so much so indeed that the mere quantity of these apparently harmless fluids which they drink is quite sufficient in itself to ruin their digestive powers. Many people think that it is only necessary to substitute these supposed harmless fluids for alcoholic drinks to pro- duce a cure. The idea is entirely fallacious, as large quantities of those fluids are as likely as not to induce dipsomania itself. There are two classes of dipsomaniacs that are very different from each other in their habits of eating. One set has the most voracious appetite, eating enormous quantities of meat, cooked in all forms. These patients are generally wine-drinkers, and very often claret- drinkers. Another set of patients eat very little, their stomachs being unable to retain or digest the food. In the first class the large quantities of food taken is not properly digested, as is evidenced by their constant call to get rid DIPSOMANIA : ITS HISTORY AND RELATION. 37 of their excrement. In fact some of these patients seem to occupy a great part of their time by evacuating their bladders and rectums of the large quantities of food and drink they ingest. The diet of those who only eat a small quantity is generally a meat one. Tlieir usual routine of life consists in getting up early or late in the afternoon, rarely in the forenoon. But dur- ing the morning they have been taking continual small doses of beer, champagne, hock, or claret, generally diluted with soda or seltzer, and have short snatches of a boozy sleep. Having come out by the afternoon they attempt a dinner in the evening, and with a fair amount of liquor in them, they bring themselves up to the scratcli to play bil- liards or cards, but they soon get tired, as tliey call it, and lie down and go off to sleep. By about one or two in the morning they wake up, and from then till eight or nine is their miserable time. They cannot sleep. The effect of the liquor is passing off and they get frightfully nervous. They often wander about the house, and if tliey cannot obtain any liquor before the general hour of rising of others, they are usually reduced to a state verging on deli- rium tremens. Directly they get some liquor, however, they go and undress and go to bed, and so on till the afternoon, when the repetition of the niglit before takes place. In the early history of dipsomaniacs they have usually had one or more attacks of delirium tremens, but after recovering in a way from them they are never able to drink the large quantities of stimulants they used to do formerly, as they get so mucli sooner prostrated and intoxicated that they never get real delirium tremens again. We have seen patients in whom the disease is of long standing so altered that one or two glasses of beer would make them quite boozy. Also, after the attacks of delirium tremens, they never seem to recover tlieir muscular tone and power, and consequently cannot go tlirough the same amount of exer- cise. The reason of this is of course that they go on drinking. 38 DISEASES OF INEBRIETY. If tlieir liquor was stopped, pliysically they would get quite well. A characteristic sign of the clironic dipsomaniac is a diffuse roseate hue of face and neck and a watery aspect of eye. They are generally full-bodied, but they are always weak on their legs, and late in the disease get into almost a state like locomotor ataxy. Besides the roseate hue of face there is another symptom indicating the determination of blood to the head, and that is a constant recurrence of slight hemorrhages from the nose. The pocket-handkercliiefs of dipsomaniacs always contain secretion mixed with blood. This is only found in old standing cases, and is often alone due to the congestion of the liver, which is constantly pres- ent. The urine in the morning is generally very high col- ored. The pulse in the morning is also always weak, soft, and small. We have already stated our belief in the absence of any moral feeling in these patients. It is hard often to decide whether the drink may not have removed their moral sense by its effects on the brain. For a man may have pos- sibly started in life with a fair proportion of the moral sense, but the physical action of alcohol on his cerebrum may have destroyed his moral appreciations. No doubt this occurs in truly acquired dipsomania. But in these latter, the disease comes on later in life. Where the disease is hereditary, and is an insanity, and begins earlier in life, one generally finds that even in their boyhood they evidently were devoid of moral sensibility. The cunning of these patients in using every artifice to get drink, when they know efforts are being made to keep them from it, is really wonderful. They will hide bottles of spirits among their clothes. They will, in the earlier stage, walk long distances so as not to be seen drinking, will use persuasions and threats to those attend- ing on them, and will eventually beg anybody for drink to satisfy their craving. The symptomology of inebriety is far more familiar to the reader than its philosophy and causation, hence it is omitted for want of room. CHAPTER V. SOME CONSIDERATIONS OF THE PHILOSOPHY AND HIGHER RANGES OF CAUSES. Men in the world can be very readily graded, as they ascend from tlie lowest to the highest types, by two very essential qualifications — the one, their degree of intellectual sense ; the other, their degree of moral sense. By the lowest type of men we mean one both ignorant and immoral ; by the highest type, we mean one both intelli- gent and moral These two qualifications can, to a consid- erable extent, be separated : we often speak of the 7netttal and w^ra/ qualities as distinct; and we recognize the fact that in tlie same individual, frequentl}', the levels of these two qualities do not correspond. For instance, we can have one person, who will grade higher in his morality than in his intelligence, and another, lozver in his morality than his in- telligence. Tlie rule, however, is, — the ability to think is accompanied by an equal ethical ability. In the gradual advance of a race from savagery to civil- ization, their progress is occasioned by and marked by grad- ual improvement in both these particulars. In any man, his intelligence and his ethical ability are raised to a level corresponding with his previous practice in performing these kinds of action. The savage, compared with the more advanced man, is inherently less able to per- form these kinds of thouglit, and as he progresses upwards towards civilization, through generations, there is a gradual improvement in his ability, until as a most advanced man he finally has most capacity to think and to do right. 39 40 DISEASES OF INEBRIETY. The first essential in an advancing man, or advancing race, is activity. An indolent, idle man or race never ad- vances. It is the activity or exercise of the brain that increases its ability. Accomplishments and excellences are acquired only by practice and exercise. The rapid competitions of active society, therefore, ne- cessitate activity on the part of the individual to avoid sup- pression and elimination. Hence, improvement of individ- uals is most rapid in active society. The continuous brain- w^ork, which under such circumstances becomes a necessity, improves the thinking ability of the rising man. In the rising man, because it is a necessity, his intellect- ual (competive) ability antedates to some extent his ethical sense. In a society which is advancing from a savage to a civilized grade, competitive ability is acquired before ^^w^xsX communal interests require the harmonizing of the com- petitions. The safety and the welfare of society soon demand that the competitions of its membership shall be harmonized. This gives rise gradually to the evolution of higher and higher rules of conduct. Public opinion and moral sense, with laws and government to enforce them, thus become of a higher and higher grade, until the highest type is reached. In this gradual improvement of society, the advancing man is more and more practiced in ethical observances, until, as an accompaniment to his improving ability to com- pete, there also grows in him a better ethical sense of the rights of others. A high ethical sense may well be called the capsto7ie of human improvement. In the best communities to-day we find some individuals — in most communities they are few, in no community do they reach a majority — who have a high order of ethical sense inherent in them. These persons are always inherently intelligent, for it takes the highest order of intelligence to so understand the complexities of civilized competitions as to be able to formulate and maintain high rules of con- PHILOSOPHY AND HIGHER RANGES OF CAUSES. 41 duct to suit them. Such a high order of man — highly intel- ligent and highly ethical — is only the result of a long line of generations of this kind of practice. We spake of civilized countries, and of civilized societies as though their membership were uniform. This is not so. Every community, even that graded highest, will furnish examples ranging all the way down from the highest type, just described, to the lowest. In any community, in a so- called civilized country, we can find persons who inherently grade very low in thinking ability and in ethical sense. They are at the savage level. A great many have the sav- age level of moral sense, while they hold a higher level in intellectual sense. This, in my opinion, is particularly the case with deteriorating or degenerating individuals, they have lost their ethical sense in advance of their intellectual, — the latest evolved and most delicate goes off first. We have not yet invented a cerebral dynamometer, by which we can test and record a man's intellectual capacity or his moral strength, but in our associations with others we instinctively recognize such information to be very valuable. It is interesting to note how much we are engaged in this very kind of work. We are continually making estimates of this character, and it is astonishing, in a crude way, how expert we become at it. In making our estimates in society, the position a per- son holds is one to which he has arisen from a lower level or one to whicli he has lapsed from a higher one. Human brain ability is not by any means a constant quality — there is no standstill level. The index rises and falls in the course of the life of the person, and also it varies in the course of the line of descent. In so-called civilized society the lapses probably constitute the large majority of the incompetent. Ability, at whatever height it occurs in an advancing man, is raised to tliat level solely by previous brain practice. The practice is either personal or ancestral. The person 42 DISEASES OP INEBRIETY. receives his ability at a certain level from his ancestry and raises it or lowers it by his habits of thouglit. By far the best and most stable ability is that which is the result of practice reaching through a long ancestral line. While it is true there is only one way of improving brain ability, namely, by activity, there are several ways of lower- ing it. There are several ways in which the /tz/x^^ members of society have reached their levels. Brain inactivity, I have already stated, is ihe^ physiological method of lapsing. There are a number of pathological methods. Our pathology is always injured or impaired physiology, so I have dwelt this long upon the physiology of cerebration, in order more properly to approach its pathology. Whatever injures the structure of the brain impairs its functional action. Tliis impairment is exhibited in altered conduct, in a loss of ability, both intellectual and ethical. We can go tiirough the wards of our insane asylums and find numbers of men, who once ranked higii in intelli- gence and in morals, now lowered in both. Defect, injury, or disease now renders the brain of each of them less able to perform at as high a level as it formerly did. Insanity, indeed, is only a name we give to a certain degree of brain incapacity. As generally defined, it simply means there is such a degree of incapacity as renders the person an tinjit member of society. For this reason, for his own or his neighbor's safety, he has to be placed under for- cible restraint ; his brain is so lowered in intellectual ability that he is unable to compete for his living, so a support has to be given him ; and it is so lowered in ethical ability that he is a nuisance or a danger to others, so he has to be restrained. In society, short of the degree called insane, we have innumerable varieties and kinds of disability, exhibited by the peculiar, the cranky, and the delirious. Besides the long list of diseases, traumatisms, and PHILOSOPHY AND HIGHER RANGES OF CAUSES. 43 defects of the brain, which impair its functional capacity, we also have a long list of drugs, wiiicli, taken into tlie circu- lation, bring down tlie brain's capacity to a lower level. I need not go over the long list, nor point out the pecu- liarities of their actions, but at once mention alcohol ns one of them. This agent, from its general use, brings down more brain capacity in the world — and it certainly does a great deal to produce the lapsed me?nbers of civilized society. If it were not for the fact that alcohol has in the system a special effect upon nerve centers, particularly high brain structure, men would never have used it as a beverage. In seeking and taking it the alcohol drinker is after its brain effect. The brain is the organ of thought and all conscious ac- tion. The partially hardened condition of its delicate struc- ture that alcoiiol produces, renders it less capable of cellular motion or action. Its conscious sensitiveness is lessened thereby. It is less able to feel. The alcoholized man there- fore says he " feels better" or " feels good," and acknowl- edges that this kind of lowered sensitiveness is what he likes. He " feels better" if his brain feels less any discom- fort or pain he may have. Even in health, if he have no special discomfort, the benumbed condition is a more com- fortable one. The well man therefore says he " feels good.** Tiie luxury of alcohol drinking consists in this condition of the brain. I wish to draw attention to the fact, that in order to obtain the pleasant, comfortable condition of lowered sensi- tiveness, the alcohol drinker does not avoid or fail to have.the alcohol effects on his brain — there is a general lowering of function. When the brain's ability to feel is lowered, its ability to think and to adjust conduct ethically are also lowered. The keenness of a high ethical sense is probably ihG first thing blunted. The disability of the alcohol drinker will vary accord- ing to the amount taken; according to the inherent strengt/i 44 DISEASES OE INEBRIETY. of brain structure ; and according to the length of time the brain-abuse is continued. For instance, first, according to the amoutit taken, con- scious sensitiveness lets down from a slightly benumbed, comfortable condition, to that of complete anaesthesia ; intellectual ability varies from being " a little off " to the condition of a temporary dement ; the ethical sense varies from slight indecorum to full viciousness or madness. Secondly, the degree of brain disability under alcohol will vary according to the inherent brain strength of the drinker. Weak brains will be lowered in ability more than strong ones, and low grade savage brains, or defective ones, will exhibit their incapacities in the lines of their deficiencies. Thirdly, the disability will also vary in proportion to the /(?«^/// t*/ //;;;^ the drain-drug abuse is continued. A single debauch can be fully recovered from, but long-continued use produces such an injury the full function is never restored. Sometimes all three of these conditions obtain in the same person ; when this is the case, the degeneracy of brain function is extreme. The inebriates constitute this extreme class, always degenerated to a very low level in intellectual sense and ethical sense. Of course there is a tendency to return to previous capacity when the brain-drug abuse is left off^, but I question whether an inebriate's brain is ever fully restored to its previous capacity, or ever reaches the level it would have occupied without the injury. As society advances from a savage to a civilized level success depends more and more on brain strength. The most advanced society pays the highest premium for brain ability. In active civilized society, the safety and success of the individual depend almost altogether upon this qualifi- cation. In savage society, the muscle strength suppresses the weak, in advanced society it is the brain strength of the more competent that suppresses the incompetent. The drinkine man lets down in business and loses his PHILOSOPHY AND HIGHER RANGES OF CAUSES. 45 money because his thinking capacity is lowered by his habit — his ability is weakened. The drinking man also lets down in mor-dls, /al/s into vicious habits, because liis ethical sense is weakened. In modern society, brain idleness probably puts most men into the eliminating level ; next to idleness comes alco- hol. These two agencies rapidly rid crowded society of their unfit membership. Nothing is so rapid an elimi?iator as alcohol. The least fit, both in the idle wealthy ranks, and in the idle poor ranks, are most given to its use. Under the light of advancing science, the use of alcohol is becoming more and more confined to the class of the weak- brained and the vicious. The intelligent, for the sake of maintaining this intelligence and superior fitness, are learning to leave it off. Society is much interested in the intellectual level of its members, but it is most interested in tiieir ethical level. The safety and survival of tlie individual are most depen- dent upon his intellectual ability ; society, though, is prin- cipally interested in his ethical ability. The safety and welfare of society depend upon the moral status of its people. The good of society demands this. Communities, races and nations, like individuals, are engaged in competitive life. The most successful is the one which has the high intellectual, progressive capacities of its people welded into a harmonious, united whole by a high ethical sense. There is a very satisfactory scientific explanation there- fore to the fact, that the most altruistic persons, those most interested in public good, have always been opposed to alcohol drinking. They recognized the fact that it lowered the intellectual and moral abilities of the people and tended to weaken and disintegrate society. Probably one reason they have never succeeded better in enforcing their opinions upon the attention of the alcohol users, is because they have not had the advantage of recent scientific knowl- 46 DISEASES OF INEBRIETY. edge to back their instructions — the brain has been left out of their philosophy altogetiier. I have often been make impatient in listening to the lec- turer presenting the " scientific aspects of tlie alcohol ques- tion" to an audience, to see him illustrate extensively with charts and spend hours to show the effects of alcohol upon the coats of the stomach, and upon the structure of the liver, the lungs, and the kidneys, and never allude once to the brain, when the fact is, alcohol's principal effect is upon this organ ; and the functions of this organ so far transcend the functions of all the others, that, I might say, there is no comparison. When the individual in society is taught the fact, which he seldom knows, that alcohol incapacitates this very organ upon which his safety and success in the competitive world depend, he will be very much less inclined to use it. And when society recognizes that with alcohol a low-grade, vic- ious man can be made chemically out of its excellent man, and that tliis process is continually going on among all its ranks, it will be more alive to spread scientific instruction upon the subject. CHAPTER VI. INEBRIATE DIATHESIS AND ITS CONDITIONS AND RELATIONS. By the inebriate diathesis is meant that constitutional pro- clivit}^ or neurosis, which impels to the inordinate use of narcotics. This includes the hurtful consumption of opium, chloral, cocaine, etc., as well as of alcohol. The latter, however, will be more particularly the subject of the present inquiry. The peculiar bent of the constitution herein referred to has been classed as a specific mania ; and has been called by Dr. Norman Kerr and otliers tiarcomania. In the interest of brevity, I will begin what I wish to advance on this subject with a homely illustration. We are assured by anatomists that the bones of the skeleton — it matters not what shapes they assume — are, as to form, modifications of a single fixed type. This type is repre- sented by the separate and distinct bones of the spinal column. When we attentively consider the group of nervous maladies known as the neuroses, we perceive that they bear a close relationsliip with one another. We learn that either member of this family may assume the character- istics and features of some other member. We become aware of the fact that, seemingly, one of them may be transformed into the semblance of some kindred neurosis. We see that this transmutation may be effected through the operation of heredity — a neurotic form in ancestry appear- ing as a different form in posterity. We are also impressed 47 48 DISEASES OF INEBRIETY. that this interchange may even take place in the same per- son ; as when epilepsy, or dipsomania, gives way to amnesia, or some other neurosis. While it is reasonable and necessary to study the bones of the skeleton separately and individually, in order to arrive at right conclusions respecting the body as a whole, it is also philosophical, and, indeed, essential to a correct apprehension of the subject, to study with care the distinct type of which these bones may be modifications. It is desirable to examine the spinal bones, so that a proper estimate may be made of the nature of the modifications assumed by various parts of the skeleton — and the reasons of them. The true and perfect type of which the entire assemblage of neurotic maladies is representative, is, it appears to me, simply epilepsy. The varying aspects which this disease assumes, its several grades of intensity, as well as its origin, — so far as that is known — seem to point it out as the great central source of the several neurotic besetments. If this be true, even in a general sense, it follows that in seeking the origin of the inebriate diathesis an examination of the causes and phenomena of epilepsy will be a necessar}' work. Epilepsy has been classified as either centric or excentric. That is to say, it arises sometimes from causes situated within the brain ; and at other times, from causes exterior to the brain, but influencing tlie condition of that organ. These causes, while often attended by pain, may operate without exciting actual pain. In epilepsy there is a con- stant, unrelenting irritation, nagging the great nervous center. This irritation may be simply a morbid impres- sion acting through organic sensibility, or it may be attended by actual pain and distress. Hence teething, indigestion, and worms excite convul- sions in children, which are epileptoid. So, too, tape- worms, affections of the liver, or stomach, or kidneys and the like, may excite true epilepsy in the adult. It is INEBRIATE DIATHESIS AND ITS CONDITIONS. 49 obvious that epilepsy from such causes is more or less amenable to treatment. But the treatment of centric epi- lepsy — frequently hereditary, with its proximate cause within the brain — is more difificult ; and usually the most that can be expected is a certain toning up of the general constitu- tion, by which means the effects of the original evil may be better endured. Through such measures some hope may be entertained, perhaps, that the violence of the epileptic seizure may be abated. In short, some slight possibility may appear, that, instead of true and complete epilepsy, there may be substituted amnesia, or neuralgia, or some other and milder one of the neurotic forms. An educated and refined gentleman — now a retired clergyman — once suffered with repeated and severe attacks of epilepsy. The coma continued many hours. The epilep- tic form disappeared under treatment ; but it was followed by seasons of absent-mindedness (amnesia), lasting for days. No recollection of the life of this neurotic trance was or is retained. The same individual suffered after- wards for nearly two years with excruciating pains. They were referred at first to the stomach, cancer being feared. Subsequently they were located in the pleura. Finally the trouble was attributed to biliary calculi. The "cure" was complete, sudden, and unexpected. No calculi ever put in an appearance. Tlie physician in attendance upon the case in its neuralgic form had no accurate knowledge of the previous history of his patient. Central or centric epilepsy is often hereditary. But that fact does not militate against the idea that irritation is the primum. mobile of the disease. The misshapen head, the undeveloped brain, may readily be supposed to act as sources of unceasing irritation. Injuries to the head pro- ducing epilepsy are too common to call for remark. Know- ing, then, that irritation is an efficient cause of epilepsy in all cases where its cause has been satisfactorily determined, we are justified in assuming that in those cases where the 50 DISEASES OF INEBKIETY. source of the malady does not plainly appear, the high probabilities are that some undiscovered or masked point of irritation is nevertheless operative as the proximate cause of the disease. I sa.y proximate cause — for it is evident from the fact that irritation does not always produce epilepsy, that, after all, there must be some peculiar predisposing constitutional susceptibility in epileptics that is not found in people gen- erally. And here is the key which unlocks at least some of the secrets of heredity. It is the peculiar impressibility of the epileptic constitution, which, being hereditary, makes possible the heredity of the disease itself — circum- stances favoring its full development being presented. It also makes possible the heredity of those neurotic forms recognized as kindred with epilepsy. This constitutional susceptibility therefore explains the heredity of inebriety, hysteria, chorea — epilepsy itself. It explains the heredity of dipsomania, and all the features of the inebriate diathesis. When there is present a peculiar constitutional tendency allied to the epileptic diathesis, then any irritation of nerve — if severe and unremitting — will be likely to develop some form of neurotic disease ; and this will correspond, not with the nature of the irritation itself, but with the nature of the constitutional trend. Dr. Cheyne refers to a case of epilepsy " which was caused by a cartilaginous tumor of the size of a large pea, which was situated on a nerve. Upon excision of the tumor the fits ceased." Why may not inebriety — narcomania — be developed by causes as small and apparently as trivial ? We are admonished to look for the pathological condi- tion provocative of inebriety. Wliy not insist upon some invariable pathological condition in explanation of epi- lepsy ? Very often, indeed, this morbific cause cannot be determined ; but when it does appear, it is always found to consist of some point, or points, of unflagging and INEBRIATE DIATHESIS AND ITS CONDITIONS. 51 remorseless irritation. It may be repletion, or it may be famine and weakness. It may be too much blood, or too little blood. It may be observed in the center of the cir- culation — the heart — or it may reveal itself in irregularities and disturbances of the equilibrium among the arteries, veins, and capillaries. But virhatever else it is, or wherever located, it is irritation worrying and exhausting the nervous powers. Now certain constitutions bear up through the changes of life fairly well, until some serious injury overtakes the physical organization, such, for example, as a blow upon the head, a wound in battle, or even a long and trying ill- ness. Irritation at once begins to do its work. The ordi- nary and natural constitution gives way. It is weak, exhausted, weary. It has become unequal to the require- ments even of ordinary life. It reaches out for aid, or rather for rest and repose. Tlie inebriate diathesis is established, and the anaesthetic — the lethal influence of narcotics, and especially of alcohol — is invoked. The call is not feeble and uncertain, but earnest and reckless. An habitual drunkard "shot a bar-keeper and set fire to a saloon, without the occurrence of any quarrel or dispute. A homicide was hung. A post-mortem revealed a splinter of bone that had pressed upon the brain for ten years, the result of a blow upon the head." The drinkinghabit began shortly after tlie infliction of the injury, A daily paper of Cleveland, Ohio, dated October 13, 1886, contains a pitiless notice of the downfall of the Rev. , a clergyman living in the city, " In the gutter again," was part of the heading. The account says the reverend gentleman was sent to the workhouse, and also contains a notice of the dismissal of the deliquent from his position in the church, with a warning to the Christian public to beware of him. On the 6th of October, 1891, after the lapse of about five years, the same daily journal contains a sympa- thetic account of a. post-mortem held upon the body of the 52 DISEASES OF INEBRIETY. reverend gentleman. This was had in an insane hospital in which the unliappy man had been placed. T\\\% post-mortem disclosed the fact that the man was carrying in his lungs a bullet weighing over one ounce, received w!ii!e bravely fighting the battles of his country in the war of the rebellion. It is evident that the treatment proper for inebriety must occupy a very wide field, as its proximate causes are so varied. It is filled with innumerable facts, requiring the utmost skill, both in observation and discrimination. In its very simplest view, three considerations must be kept before the mind : ist. The causes of inebriety. 2d. The nature of the drunken state. 3d. The functional disturbances and physical degenera- tions that are sure to follow long-continued habits of intemperance. The Diathesis and Cachexia of this affection has never been carefully studied, but, standing on the border, we catch intimations of its vast possibilities, awaiting the future investigator. A diathesis implies a special predisposition to certain kinds of diseased action. A. cachexia is a developed dia- thesis, a real condition of disease of the blood and tissue. A diathesis is a more or less remote cause, but a cachexia is a present part of disease, an influence on the organism. Using these terms together, certain well defined conditions appear to be traced, from which inebriety can be studied and prognosed witii much certainty. The first and most common form seen may be classified as the nervous diathe- sis and cachexia. They may be noted by their spare bodies, light hair, changeable countenances and restless animation. Easily agitated, intense functional activity, so sensitive as to show signs of mental disorder when excited. Mentally their views of life are unreal, visionary and exceedingly changeable ; seldom calm and deliberate, but abrupt, jerking, and when exhausted, prostrate. When INEBRIATE DIATHESIS AND ITS CONDITIONS. 53 this is inherited it is often accompanied by a vain, weak mind, witli boundless self-esteem, always on the verge of eccentricity. The mind dashes from one extreme of emotion to an- other, either showing excitement that is morbid, or degrees of feebleness that are abject. Women are often of this class, and persons from the wealtliier circles of social life. Luxurious habits, indulgence of wliims and fancies in childhood, are active causes of such a diathesis. This is a distinct type of mental defect from which inebriety and insanity are an almost constant sequence. An early diag- nosis and prognosis, with treatment, would furnish the only practical means of escape from this diathesis. An- other condition may be noted, called Strumous Diathesis and Cachexia. Here the patient has diminished vital en- ergy, imperfect nutrition, with mental weakness and perver- sions, unnatural special developments, which have a con- stant tendency to exhaust themselves, as, for instance, in case of extraordinary mental or physical genius, where the body is out of all proportion. Many of the so-called great men of the world belong to this class. They are nearly always anaemic, complain of frequent headaches and have often a tuberculous history, accompanied by a species of degeneration which has a constant tendency to concentrate in some particular organ. Any exposure to cold takes on an aggravated type of symptoms, or injury to any organ assumes the most alarming phase. The nerve centres are always more or less involved, and siiocks or injuries are acutely felt. Inebriety appears as a part of the natural history of this diathesis. Paroxysmal drunkards belong to this class, and of all others they are the most thoroughly demented during the attack. In many cases an Arthritic Diathesis and Cachexia are well marked. Here a chronic state of imperfect nutri- tion, with mental exaltation, or depression existed. In many cases a history of rheumatism and deposits about 54 DISEASES OF INEBRIETY. the heart, with calculi of gall duct and bladder were given. The circulation was weak, and the intellect un- stead\\ A capricious, irregular appetite accompanying these conditions often forecasts inebriety, and generally precedes violent attacks. A Syphilitic Diathesis and Cachexia are known by temporary headaches, amaurosis and flying pains, with mental and moral defects of various grades ; anaemia and affections of the heart are often present. This, with a clear syphilitic history, are evidences beyond ques- tion. In this, diathesis inebriety or insanity develops from the least exciting causes. There is a He77iorrhagic Diathesis and Cachexia^ which is characterized by anaemia, blood deficient in fibrin, suffering from persistent neuralgias, and a constant tendency to copious hemorrhage from the slight- est causes. Inebriety often follows from this condition. Two cases have fallen under my notice where this diathesis ended in uncontrollable drunkenness and death, A Fibri- nous Diathesis and cachexia may be the active cause of ine- briety by the constant tendency of the blood to exudations of unhealthy plasma, and general hypertrophy and indura- tion of the cerebral system, all the functions being lan- guidly performed. In all these cases the normal equili- brium of the nutritive functions is destroyed, and inebriety follows as the first stage of degeneration. These are some of the many conditions of the body coming down from in- heritance, well marked, and so often preceding this affec- tion, as to be called active and predisposing causes. These conditions are not always distinct, but blend into each other, multiplying and diverging. CHAPTER Vir. GENERAL PREDISPOSING CAUSES. A Study and grouping of the general causes will afford data, from which we can understand inebriety in its first manifestations. The first group, called General Causes, are those which frequently produce inebriety in common with other insanities. Of these vicchanical injuries seem prominent, such as injuries or concussion of the brain and spinal cord, and consequent alterations of nutrition. Blows on the head are not uiifrequently followed by violent paroxysmal drunkenness ; railroad accidents, where the concussion and surprise are sudden and overwhelming, causing intense re-action on the nervous system (produc- ing at first insignificant physical lesions), often develop inebriety and mania, A chaplain in the late war, injured in the leg by a shell, although but a simple flesh wound, was several months in the hospital before recovery. From this time he became an incontrollable drunkard, and eventually died. A prominent physician was precipitated from his carriage on the head, and received flesh wounds of a minor character. Very soon after inebriety was devel- oped, and he ended his life a raving maniac in an asylum. The rule in many cases indicates that injuries of the brain, spinal cord, or any part involving numerous nerve trunks may end in cerebral disturbance, of which drunkenness is a very common stage of the lesic^n, the injury being small in comparison to the mental disturbance which follows. Peripheral irritation or reflex excitability has been noticed as a common cause in many cases. In a letter to the 55 56 DISEASES OF INEBKIETT. Psychological Joicrnal, a physician describes two cases where tape-worms excited inebriety and mental liallucina- tions, which disappeared on tlieir expulsion. Several instances are on recoid where the use of pessaries in pro- lapsus uteri and the prolapsus alone, has been the cause of mental disturbances of which drunkenness was the most prominent symptom. The irritation from prolonged lactation, or in dysmenorrhaea, ammenorrhea, nymphomania and functional disturbances of the genital organs, are frequently the beginnings, and in many cases the active causes of this disease. A case of chronic masturbation, which ran into inebriety, came under my notice lately. Numerous cases of puer- peral insanity, preceded or followed by inebriety, are recorded in the English obstetrical journals. Cases of drunkenness during pregnancy, ending at delivery, are not uncommon. A remarkable case was noted at the Dublin Lying-in Hospital, some years ago, of a woman, who during the period of lactation, drank gin to excess. This craving for stimulus began when the child was born and continued until the death or weaning of the child, the former being the most common termination. When lactation ceased the desire died away. Another case of equal interest is reported in a western journal. A soldier, wounded at Pittsburgh Land- ing, previously temperate, became a paroxysmal drunkard. A portion of the shaft of the femor was injured, and con- tinued to exfoliate dead bone until 1873, when it was removed by an operation. From the healing of the wound his drunkenness disappeared, and he is now one of the most enthusiastic of temperance men. Previous diseases are also active causes. Dipsomania, erotomania or monomania often are associated with epilepsy in some of its obscure forms, as natural stages in its progress. Epilepsy, with its disordered fancies, auras and impulses, ending in apparent recovery, only to be followed after time by a repetition, closely simulates the impulsive drunkard. GEJSTEEAI. PREDISPOSING CAUSES. 57 The connection between inebriety and epilepsy is far more intimate than we are aware. Affections of the heart, either organic or nervous, and low chronic hepatitis, predisposing to hypocliondria and melancholy, very often precede this affection. Neuralgia often ends in this way, by disturbing the mind centres and its equilibrium. Gout suppressed has brought on inebriety, but when it returned, drunkenness declined. Intermittent and malarious fevers have been fol- lowed by this disorder, and the medical attendant has been blamed for causing it, by prescribing stimulants. Persons suffering from acute rheumatism, after the severe symptoms have subsided, have exhibited the same affection. Diseases of the skin and renal disturbances have been noted as pre- ceding drunkenness. Diseases of an intermittent character (a hint of nerve complication) may be the primary cause of drunkenness, through the perversion of functions, beginning so obscurely as not to be noticed. Dietetic diseases seem more frequently associated as causes owing to the intimate association between the nu- tritive functions and the nervous system. Dyspepsia, with all its train of perverted sensations and tastes, have often common sequence in this disorder. Excessive hunger and thirst are followed conditions vyiiich are often active causes. Indigestion, inflammation of the stomach and liver often leave a train of predisposing causes. Practically, any disease influencing or breaking up the nutritive functions of the body, has its first effect in perversions and cerebral dis- turbances, of wliicii inebriety is a frequent result. Indi- vidual iiistories of neglect of hygienic care, followed by indigestion, dyspepsia, hypochondria, drunkenness and death, can be traced in every community. Exhaustive intellectual and physical exertion, by break- ing up healthy cerebral action, may develop insane longings. Over stimulation of the brain ends in structural changes and perverted tastes for alcohol or narcotics of some kind. 68 DISEASES OF INEBRIETY Scholars, and tliose who use the mind to excess, and laborers, who only exert the physical system, when exliausted from over work, have unnatural longings for something to restore the lost balance of mind and body. A prominent senator spent thirty hours continuously in tiie preparation and delivery of a speech, and became an inebriate from that time. The proprietor of an ice-house offered some men large wages to continue the work of filling the iiouse ; being expert workmen they continued without much rest for fifty hours. Two out of five became drunkards, and dated it from this time. Instances of similar character are not uncommon. Sud- den excitement and exhaustion acts in the same way, one physiological effect is rapid contraction of the arteries, apparent in the pallor and consequent anaemia of the brain. The shock imparted to the senses through the mind, extends to the brain cells, producing similar commotion, often breaking up their normal action forever. The sudden loss of property, disappoiniment, trouble, unrequited affection, may so depress the vital powers and disturb the circulation, that drunkenness or insanity, or both will follow. Ambition to lead, wliere it becomes a domin- ant passion, filling up every moment of tliought, lowers the nutritive functions and leads directly to perver- sions of taste. Religious activity, where the mind over- flows with sentiment and emotion, may react into violent gluttonness or^inebriety. No class of men are so thoroughly dyspeptic as clergymen and lawyers ; simply the reaction of the mind to restore the equilibrium broken up b}'^ irregu- lar exhaustive labor. In every community large numbers of this class are on the verge of inebriety. The capricious appetites, and the excessive thirst for tea, coffee, cider, soda, lemonade, etc., etc., and the bitters and patent medicines consumed to cure ills that are imaginary, are all early stages of this affection ; a change of surroundings, and they become inebriates in the fullest sense. GENERAL PREDISPOSING CAUSES. 59 Maudsley thinks tliat tlie depraved l:>nging's of inebriates are greater in the morning, particularly if following exhaus- tion and anaemia, owing to tlie contracted blood vessels dur- ing sleep, which have not had time to recover. Confirming this, a case under my care has strong cravings for liquor in the morning, whicii, if broken up, does not return until the next day. This craving for unnutritious fluids, or substances, generally indicates impending brain disorder. Excentrici- ties of character are frequently associated with inebriety. The poets, artists, and scholars, and warriors of the world, who were inebriates, are examples. Their minds, dashing beyond the bounds of normal, mental and physical life, reacts in nutritive excesses. Of this class we might men- tion Alexander, Philip and Nero, among the warriors ; Shakespeare, Byron, Burns and Poe, of the poets ; and John- son, Addison, Pitt, Sheridan, etc., etc., among the scholars. An unbalanced mind resulting from a misdirected educa- tion is the common cause of inebriety. Where the laws of growth and elementary power are untaught, and the child grows up without any purpose or object in life, the facul- ties undisciplined, the appetites and tastes indulged, no system, only the gratification of the physical wants, no par- ticular knowledge, the love of excitement constantly stimu- lated, and self-esteem encouraged, add to all this, predomin- ant passions, extravagant and capricious desires, and drunk- enness is almost sure to follow. The present system of cramming and over-stimulating children, in the study of imperfect text books, in worse surroundings, lays the foundation for both physical and mental dyspepsia, hypo- chondria and dipsomania. Two-thirds of our graduates leave the schools with unnatural and perverted tastes, feeble will-power, and ignorant eccentricities, strongly predispos- ing them to inebriety; all they need is the exciting cause, the fertile field is prepared to receive it. The perpetuity of the race depends upon the education received, from both school and parents. It the child grows up surrounded witli 60 DISEASES OF INEBRIETY. unnatural, morbid, influences and ignorant indulgences, and worse school education, its ruin is inevitable. Under the third group are included all those conditions and circum- ■■* stances which seem to particularly favor the development of inebriety. Of these, age has a controlling influence. It is well understood that the body has various stages of development and decline. These are really physiological eras in the organization, whicii have prominent pathological relations, influencing the nervous system, and markedly controlling its disorders. Statistics of the time of life when inebriety begins, or when the predisposing causes are most active, are wanting. From an examination of a large number of inebriates at the Albany Penitentiary and a comparison of records elsewhere, the following facts seem to be indicated. Inebriety occurs in manhood, or midway between the weakness of infancy and the decline of old age, at a time when the brain has reached its period of fullest activity. The development of the mind and nervous system, from simple conditions to complex stages, is followed by an increase of the range of its susceptibilities and diffusion of its powers, and also greater exposure to morbid influences. In adult life the struggle is at its height, all the faculties are intensely occupied, the fullest capacity of mental and physical energies are exercised. The ambitions, disappoint- ments, and changes are sudden and far-reaching. The over-weaning confidence in the physical and mental powers of recovery, cause recklessness of effects. Inebriety appear- ing in adult life, may be the result of perversions of devel- opment, beginning in infanc)^ Such cases are generally associated with some form of mental disease. The brain power of infancy and youth, cannot bear much irritation without peril, its circulation is more rapid and susceptible to sudden fluctuations, which are intense in their influence. This is apparent in the cases of permanent injury, which follows from fear, anger or sudden emotions that profoundly impress the organism. At this time of life organic changes GENERAL PREDISPOSING CAUSES. 61 take place, which have a correlative mental transformation, the active degree of enervation existing makes the entire body extremely susceptible to commotions, in both the or- ganic and mental developments. I believe tliat future ob- servations will indicate tliat inebriety begins here, although its development may be delayed for years. Sex evidently brings certain influences which bear on the causes of this affection, although the data are wanting a few outline facts indicate an intimate relation. More men are inebriates tlian women, but a large number of the latter are concealed by their friends; also this affection merges into otiier diseases more rapidly than in man. The number of women who have mental perversions is very large, always in excess of men. Generally women suffer more keenly from inebriety than men, because they have feebler organizations, and suffer more from functional disorders and organic degenerations. Men are more ex- posed to the wear and tear of active life, involving accidents, excesses, wasting degenerations, witii larger passions and capacities, and stronger nervous and mental organization. Women, vvitli a less vigorous system, change oftener, and the evolution is earlier ; the absorbent system and circulation are more rapid. In mental diseases women recover rapidly if the sur- roundings are good, but when functional and organic dis- turbances affect tlie organism, the return to health is slower. Both sexes at puberty, pass a period of liigh functional activity, a crisis in the organic and mental growth of the body, wliich is often the beginning of condi- tions resulting in inebriety. At the menapause another revolution comes over women, which predisposes to ner- vous defects. The close sympathy existing between the sexual organs and the encephalic ciiculation, predisposes both sexes to disorders of mental and functional character, of wiiich inebriety is prominent. Social condition has been recognized as an active cause 62 DISEASES OF INEBRIETY. in inebriety ; celibacy predisposes to unnatural and per- verted impulses, which rapidly develop functional diseases. Married people lead more natural and regular lives, and their habits and pursuits are usually fixed and methodical. Home-life furnishes sympathy and outlets for affections which no otlier conditions can give. Inebriates often attempt marriage as a remedy to save themselves ; generally, inebriety, beginning either before or after marriage, predis- poses to celibacy. As a rule inebriates do not marry, nor are they true to their vows after marriage. Statistics indicate a preponderance of married men as inebriates, but a closer examination indicates a large proportion of them leading single lives. Domestic troubles, breaking up the normal quietness of life, and sudden changes of conditions, from affluence to poverty, or vice versa, often bring on this affection by destroying the equilibrium or co-ordinating power. Social changes frequently drive men into un- healthy conditions, whicli bring on perversions ending this way. Fashions and customs develop unhealthy mentality, which lead towards the same affection. In many instances we can exclude every other cause but the latter, but fre- quently social conditions only develop and excite latent tendencies to this affection. Future studies will show that the seasons and weather are agents, influencing more or less inebriety and inebriates. The changes in the organism from these causes are followed by corresponding changes of the mental condi- tions. The increased functional activity of the body in the spring, is supposed to favor the production of mental diseases ; but from the records of police courts, penitenti- aiies and asylums, inebriety appears most common and acute in the season of autumn. This has been explained as coming from moral and physical causes. The former arising from general failures, with blank prospects, loss of opportunities, and depression which follows. The latter from physiological changes, su'ch as thickening of the GENERAL PREDISPOSING CAUSES. 63 arachnoid, shriveling of the convolutions, serous effusions, with general atrophy, and wasting of the functions. Another fact well recognized is that prolonged cold and rapid changes from one extreme to the other particularly predispose to degeneration and morbid mental and func- tional activity. The effect of cold, driving the blood from the surface, preventing proper contraction by congestion of the cerebral capillaries from reflex action explains this. Barometrical changes act in the same way. Sailors, sol- diers, woodmen, teamsters, etc., exposed to these conditions, are generally inebriates, evidently due to similar causes. All unhealthy mental, physical and social surroundings, continuous excitement, and dark, damp, low places of resi- dence are noted for the inebriety which springs from them. Whatever climate or season, combined with external causes, checks or perverts the normal development of mental or physical life, becomes the exciting cause of inebriet}'^, insanity and imbecility. There are many rea- sons for believing that future studies will indicate that certain climates and seasons are more favorable for the treatment of inebriety. The temperature and condition of surroundings are evi- dently active causes. High degrees of heat and cold may so far impair the nutrition of the nerves, or produce paresis of the vaso-motor centres, as to result in inebriety. Sun- stroke, inflammations, congestions and similar disorders of the brain-cells, coming from extremes of heat and cold, are often followed by drunkenness. A fireman while overheated, took a bath which resulted in severe headache, indigestion, and finally acute drunkenness. Here the sudden abstrac- tion of heat so damaged the nerve-centres, as to bring on this affection. The Captain of a South American steamer informed me that the firemen and most of the men em- ployed (for any length of time) in this service, became drunkards ; this he attributed to tlie extremes of climate and heat which they were constantly exposed to. Leaving 64 DISEASES OF INEBRIETY. New York in mid-winter, within a few days they are in a tropical temperature, then bade again, from the literal sum- mer of the Equator to the frequent Polar temperature of New York, Inquiry among the furnace-men of Albany and Troy indicates the same fact ; men exposed to a high heat after a time (to a large extent) became inebriates. The purity of surroundings, particular!}: sleeping-rooms and places of business, (without doubt) influence tlie devel- ment of inebriety. Unsanitary conditions of every descrip- tion react first on the nutritive functions, then on the will- power. I believe further study will show tliat the nutritive perversions of inebriates frequently begin in imperfect oxi- dation of the blood, and the inhalation of noxious impurities. In this respect our reformatories, asylums and prisons are criminally wanting. To attempt reformation or treatment in damp cellars, or rooms badly ventilated, is to ignore the predisposing causes, and fix and intensify the derangement. Cases are on record of men confined for a few montiis in a prison, previously temperate, who, on coming out, became furious drunkards. The New York State Prison Association mentions this fact, and the explanation is evident in tlie poor quality of food and bad unhealtliy surroundings, strongly favoring this termination. The Almsliouses and Poorhouses of the country furnish confirmatory evidence. Children and young people who have by any misfortune been confined in them, may be said to have as a rule decided tendencies to drunkenness. Older people, past the middle of life, who come to these places, go away with the same perversions. Cellar occupants and those of tenement- houses (where nearly all the conditions of health are want- ing), are inebriates as a rule ; separate them from these baneful influences, and reform or recovery follows naturally in many cases. Working rooms, such as factories and shops, are often nuclei for the same causes. Sleeping and living rooms may present conditions which bring on disturbed nutrition, and then the train of causes are put to work. GENERAL PBEDISPOSING CAUSES. 65 The sympatliy between the stomach and brain is so intimate, and tiie changes which take place so obscnie, tliat inebriety may brealv out as tlie result of long and continuous abuses of the surroundings. Mental diseases are found to be largely controlled bv cosmical influences, such as Electrical piienomena, Lunar attractions, velocities and directions of winds, Geoloo-ical formations, elevations above the sea level, etc., etc. A professional man of great intelligence, who is an inebriate, becomes restless, depressed, and has headache and irreo'u- larity of temper when the wind blows from the South, and a storm is impending ; also before a thunder-storm. If he can resist the cravings for liquor until the storm is over he is safe, but if the moon be at a change, and the storm is delayed, he loses all control and lias a paroxysm of drink- ing. At the Albany penitentiary it has been observed, that chronic inebriates, recently confined, show a decided difference in work and temper on the approach of a storm. A clergyman, who was an inebriate in early life, cannot go near the seashore, without feeling an almost irresistible desire to drink again. On two occasions he, was obliged to go back suddenly to the interior to save himself — a few miles back the desire leaves him. These cases indicate a wide field of causes entirely unknown. There are influences wliich control the wants of tiie body which no one has yet solved ; conditions of exaltation and depression, which we all experience, of undefinable longings and tastes, a pres- sure of unknown surroundings, which may perhaps be influenced by cosmical forces. Certain districts of the far West, particularly river-bottoms, seem to present combina- tions of circumstances which end in this affection. The same may be said of certain kinds of labor. The State Board of Charity of New York have in their inquiries found certain rural districts where pauperism and inebriety seemed to flourish as indigenous. Who can predict what a farther study will disclose in this direction ? CHAPTER VIII. TRAUMATISM IN THE CAUSATION OF INEBRIETY. From a clinical study it will be found that the use of alcohol in inebriety is in many cases only as a symptom, or one of the matu^ causes that develop positive disease. It is proposed in the following study to show that physical traumatism is often an active cause of inebriety, which in most cases is not recognized. The early history of drink- ing is often a period of great obscurity, and the patient himself will have no clear idea of the conditions and causes whicli impel him to use spirits. His opinions are often misleading and never reliable unless confirmed by other evidence. If he has been taught to consider inebriety a vice and sin, his ideas of the early causes will be governed by this impression. If he has no fixed theories on this point, he will usually have some notion of misfortune and trouble, and consequent despair, associated with the early periods of drinking. From a clinical study the views of the patient may be of value as intimations of his present mental state, and the possible mental conditions which have obtained in the past. In all cases the tendency to exaggerate and prevaricate, without any ascertainable reason, must be considered in the problem of diagnosis. There are two distinct periods in all cases of inebriety. The first, beginning somewhere in the past, unknown and not noticeable to ordinary observers, and terminating with the first excessive use of acohol. The second, starting from this point and noted by the occasional or continuous 66 _ . . TRAUMATISM IN THE CAUSATION OF INEBRIETY. 67 excessive use of spirits, terminating only in death or recov- ery. This period comes under the observation of friends and relatives, and can be accurately studied, and is supposed to include the entire field of observation. Inebri- ety begins in the first period, and breaks out in the latter. This first period is not studied, it is in the outer circle, the penumbra, or neurotic stage. The second period is the umbra, and inebriate stage. In this first or neurotic stage, the causes and conditions are as varied and complex as that which produces insanity. Notwithstanding their obscurity, they often present distinct intimations of inebriety far in advance. Every case will be found to come from some special condition of change or departure, from healthy activity in the organism, in which both the function and structure are involved. Even in this early stage, a certain progressive march may be noted, often broken by long obscure halts, or precipitous strides, changing into varied forms and manifestations of disease. This neurotic stage will be marked in most cases by nerve exhaustion, instability of nerve force, and nutrient per- versions and disturbances. Not unfrequently delusions and hallucinations about foods and drinks are unmistakable symptoms. Often persons who have never used spirits, and become fanatical in their efforts to reform inebriates, are in tliis stage, and sooner or later glide into the next one. Tliese are the general indications, associated with innumerable minor hints and symptoms, that follow from all the degrees of inheritance, occupation, surroundings, and all conditions which make up physical and mental health. Traumatism may bring the patient into the first stage, or into the second at once. Or it may leave him susceptible to every piiysical state and surroundings. Psychical traumatism, or injury from mental agitation or powerful emotions, as a cause of inebriety, may be con- sidered from two points of view. First, as a direct cause of inebriety, and second, as an indirect cause, by developing 68 DISEASES OF INEBRIETY. conditions which rapidly merge into tliis disorder. As a direct cause tlie following case is a good illustration : A merchant, previously healthy and temperate, forty-five years old, with no neurotic inheritance, was returning from New York City (wliere he had been on business), on an evening train, on tiie Hudson river railroad. Wiiile moving at great speed the cars jumped the track, and ran along on the sleepers for some distance before they were stopped. The sudden alarm, crashing of the windows, and profound agitation from fear of death, produced functional paraly- sis, and he had to be lifted out of the car. He was taken to a farm-house, and after a few days was able to go home, but complained of exhaustion and neuralgic pains all over the body. He began to use alcohol to intoxication and could give no reason why he drank. This continued for three years, until death from pneumonia brought on by exposure while intoxicated. Notwithstanding all the efforts of himself, relatives and family, he drank precipitately to the latest moment of life. He began to drink soon after the injury, calling for it with g'-eat urgency. At first it was freely given, until he was so often under the influence that it had to be removed. The second case of this character was that of a clergy- man who was in good health, a man of strong temperance scruples, and very correct in all his habits. The sudden death of his wife from a railroad accident, threw him into a nervous fever, that lasted for two weeks, after which he began to use spirits in large quantities. He claimed that he needed it for exhaustion as a tonic, and justified his use of it to intoxication. From this period he drank at all times and places, giving no cause or reason for its use except that of a medicine. He was soon discharged from the church, and became an outcast and inebriate of the lowest grade. He is now serving out a sentence for assault in state's prison. His inebriety began directly from the shock following or caused by intense sorrow and grief. TRAinviATrsM: in the causation of inebriety. 69 In both of these cases there was a degree of mental and physical vigor, that gave no indications of tliis sequel, or any neurotic disease. There was no heredity in either case that was prominent, and the inebriety was purely from psy- chical traumatism. There is another class of cases which not only have a general neurotic inheritance, but have hints of defective nerve force long before traumatism brings on inebriety. The following cases bring out these facts clearly : A lawyer, age forty-four, who was a temperate hard- working man, was made unconscious by a stroke of liglit- ning, and from recovery began to use large quantities of spirits at night. He became an inebriate and died three years after from delirium tremens. His grandfather on his mother's side died from inebriety, and two uncles were inebriates. His mother used spirits freely as a medicine for many years. Here it was clear that an inebriate diathesis existed, and was only developed or exploded by the traumatism. A farmer, who was temperate, had suffered some years from nervousness and general liypochondria, was greatly excited at the burning of his barns, supposed to be the work of an enemy. He was laid up in bed for two days, then began to drink brandy, and was intoxicated from this time to death nearly every day. Tiiere was no clear history of heredity, but iiis nervousness and hypochondria seemed to follow from some disorder which began at puberty. Some nerve defect liad lessenea tlie vigor and integrity of the organism, and tlie traumatism followed, bringing out inebriety. Another case has lately cd^ne under my care of a mer- chant, who had been well and temperate up to his business failure. This came upon him unexpectedly, and caused great mental anguish, follow by impulsive inebriety. He could give no reason for his drinking, and simply said it was impossible to abstain. His history, for some years 70 DISEASES OF INEBRIETY. befoie the failure, indicated chronic dyspepsia and general perversion of nutrition, altliough he had conscientiously refrained fi'om all use of spirits, yet liis capricious nutritive impulses exploded readily into inebriet}' from tlie action of traumatism. There are many reasons for supposing that all cases of this character, where dyspepsia and nutrient disturbances exist for some time, are peculiarly susceptible to traumatism, particularly of psychical character. The same may be said of a large class who have inherited unstable brain and nerve forces, either from inebriety, insanity, or any other organic disease. They are all more susceptible to trauma- tism and his results. All these cases proceeded directly from psychical traumatism. Whether the traumatism broke up the co-or- dinating nerve centers, which are supposed to govern the sensation of thirst, or produced some general exhaustion of these and other centers, which found in alcohol a seda- tive, cannot at present be determined. The desire for alcohol in all these cases is only a symptom of some general nerve degeneration, which has been produced by trauma- tism. In the second class of cases, where psychical trauma- tism is the cause of inebriety indirectly, the histor}'' and symptoms are alwavs more or less obscure, and require careful study. Yet these cases are undoubtedly numerous, and will in the future attract much attention. The follow- ing cases are fair illustrations : A banker, in middle life, in good health and strictly temperate, W'as greatly shocked at the death of his father from heart disease while at the table. For several weeks lie suffered from insomnia, tind could not concentrate his mind on anything, was nervous and complained of dull headache. He was under treatment for a long time with- out any positive results. Nearly a 5'^ear after he suddenly drank to intoxication, and from this time went rapidly down to hopeless inebriety. There was no heredity and no TRAUMATISM IN THE CAUSATION OF INEBRIETY. Tl ill-health up to this time. Some shoclc liad been sustained by tlie nerve centers which, from tlie application of unknown causes, burst out into inebriet3\ A lawyer whose fatlier had suffered from general paraly- sis, suddenly became an inebiiate at twenty-four years of age, under circumstances and surroundings that were tlie most adverse. After a long study it was ascertained tliat he had been profoundly agitated from tlie refusal of marriage with a lady, who soon after married a rival. Tliat for a long time he was treated by a physician for threatened brain fever, and that he never recovered liis former vigor and cheerfulness. Three years after he married into a fine family, and had every agreeable sur- rounding possible, when suddenly he rushed into a low saloon and drank to intoxication for the first time. He seemed to try and help himself, but every day sank lower and lower, and was finally divorced from his wife and cast adrift a hopeless incurable. The same psychical causes were at work beginning in the shock from disappointment, and slowly slumbering along until inebriety developed. A farmer with no heredity of nerve disease, temperate from principle and a hale, vigorous man, was greatly pros- trated by grief, while on a visit to tlie army, to find that his son had been killed in battle. For five years after he complained that he did not feel well, could not sleep soundly, was more easily exhausted than ever before, and suffered from neural- gia and changing sensations. One day, in tlie harvest field, he left his work and drove off to a distant city, drinking to intoxication. Ever after he drank all the time, with every opportunity and occasion. His excuse was that he had a tape worm, which had been taken into the system when he was in the army. Like the other cases the effect of grief and consequent shock produced some permanent alteration of both structure and function ending in inebriety. The cases were also noted by the absence of any stage of moderate drinking, and the sudden onset of the excessive 72 DISEASES OF INEBRIETY. use of alcohol. Quite a large class after some form of psychical traumatism have a stage of moderate drinking, which very commonly ends in impulsive inebriety, that comes on unexpectedly. The following are some cases, whose origin and history are very clear in many instances : A strong temperance advocate and lawyer of culture, in vigorous health, was involved in a stock company that ruined his reputation, by an accident in which he was not in any way guilty. He suffered so keenly that he was treated for fever, which lasted some weeks, then he resumed business. Later, he began to use bee*" in moderation for debility, and this in a year or more merged into stronger drinks at night. Another year, and he suddenly began to drink to intoxication every day, soon losing his business and becoming a hopeless incurable. From the time of failure of tlie company and his reputation, a steady decline of mind and body was apparent. No special symptoms could be recognized that pointed to other than general failure of his former vigor and pride of character. Some change had taken place, and something was wanting to make up health and integrity of organism. A second case was an engineer, with no history of hered- ity, and a man of fine health and thoroughly temperate. While at his work in the field, a gun in his hands w^as accidently discharged, killing an intimate friend and brother engineer. He was greatly depressed and melan- choly for months, at times would burst out into tears, and be unable to work ; then he began to use spirits at night to bring on sleep, and a few montiis after he drank to excess and was obliged to give up his business. He died a year later from excessive use of spirits. A third case, equally free from all entailment of disease, and well up to the time of great exposure and excitement from the loss of his mill by a freshet, began to use spirits for exhaustion and debility, and a few months later was a pronounced inebriate, drinking all the time. It may be TRAUMATISM IN THE CAUSATION OF INEBRIETY. 73 asked if these cases gave indications of inebriety following the traumatism ? The answer is that the period of moder- ate drinking showed this tendency clearl3\ It could not be an accident, for all of these cases were men that were fully aware of the danger of such a course, and would not enter upon it unless impelled by a diseased impulse which they could not control. It is exceedingly difificult for tliose not practically acquainted with business life to understand the constant strain and excitement which follows all business and pro- fessional activity. From the poorest laborer to the million- aire and professional man of the widest influence, there is a hurry and excitement, and a want of rest, that is steadily preparing the soil for all forms of nervous diseases. Tiie rivalry and intensity of school life follows the child to the grave. In business, in a profession or farming, it is the same struggle for prizes ; gathering up all the energies of body and mind and concentrating them in one effort ; if they fail, turning to some other field with the same intensity and courage. A prominent professor in a leading medical college and author of note, has been a teacher of languages, a mercliant, an inventor, a mining engineer, all within a career of less than half a century. These extreme changes of life and occupation strongly predispose the person to states of exhaustion, or as the late Dr. Beard wrote : " We are a nation of neurestlienics out of which many and com- plicated nervous diseases are constantly springing." Psycliical traumatism will appear oftener as a promin- ent factor in tiie causation of inebriety here than elsewhere. The following cases are typical of a class that represents one extreme of American life, tlie speculators and brokers : A broker, witli no history of heredity, healthy and temper- ate, who liad made and lost two fortunes, and was rich again, entered into a pool and sunk every dollar. His wife was taken ill, and he was forced to leave his old home, and have her taken to the hospital, wiiere she died soon after. 74 DISEASES OF* INEBRIETY. He began to use spirits to gi-eat excess at once and is now a chronic inebriate. The shock from tlie last misfortune brouglit on inebriety, and although he made many efforts to recover he always drops lower from the struggle. A banker who had made a large fortune, became a speculator and went into Wall street. He was very correct in all his habits of living and was careful of his body. For ten years he both made and lost large sums of money, and was under the usual strain of men who embark their for- tunes in one venture. His son, who was expected to follow in the same business, proved a defaulter, and was sent to state's prison. The father began to drink to great excess at once, and died after three months of extreme drinking. In cases of this character there must be a condition of great exhaustion and general debility which gives way under the last shock of traumatism. The following cases represent another extreme of life in this country. A farmer who had for twenty years worked early and late, eaten poor food, depriving himself of many necessities and comforts of life, that he might own his farm, was plunged into the deepest distress on finding tiiat the title was wrong, and all his labors had been lost. He drank at once to excess, and a year 'after was taken to an insane asylum. He was discharged in a few montiis, but continued to drink. A bookkeeper worked night and day in an absorbing passion for wealth, neglecting to rest and taking but little outdoor exercise. His position and investments were all swept away by a financial storm, and he became an inebii- ate at once. Later he was a bar-keeper, then was sent to prison for some crime. The usual explanation would be that these cases drank from despair and discouragement, but a general study will show a state of psychical pain and agony for whicli alcohol alone acts as a sedative. It very commonly appears in a study of cases of inebriety, that the [latient will refer to some event of life, or disease, from TEATTMATISM IN THE CATTSATION OP INEBKIETT. 75 which he lost some power or force whicli lie lias never re- gained. Such facts are not given as reasons for his diink- ing, but as explanations of his vigor or power of endurance. One man gives a history of overwork under conditions of great mental excitement from which he has never recovered his former vigor. Years after he becomes an inebriate, but he never traces the connection between tlie former overwork and the inebriety. A careful inquiry will show many hints along this interval (which may be years), that refer directly to this event, showing that inebriety is but the result of degenerations whicli begun there. In another case a man suffers from some profound grief and sorrow, which at the time breaks up his health, and for a long time after is felt in general debility and weakness. Years go by, and sud- denly he drinks to intoxication, and is an inebriate at once. No good reason can be given for drinking, and possibly no stage of moderate use of spirits precedes the inebriety. To himself and friends a degree of ill health has been recog- nized from the time of his great grief, and to the physician who can study closely this interval, there will be found nutrient perversions, neuralgia, eccentricities, and nameless indications of a coming storm. A very large class of cases have in the past suffered from some form of disease from which they have recovered with an entailment of debility, and a want of something that cannot be defined. They are fully conscious of dimin- ished power, of change of vigor and force. It may be they do not sleep as naturally, and do not get the usual rest ; or they do not recover so quickly when exhausted, cannot digest food as thoroughly, have dyspepsia from sliglit causes. They are more sensitive than before, emotional and excitable witli every event that is irritating. In one case a man has a severe pneumonia with a tedious, long convalescence. After recovery, a change of disposi- tion and character is noticed, and a year or so after he ^S DISEASES OE USTEBRIETY. begins to drink spirits and soon becomes an inebriate. Or another case where a man recovers from typhoid fever, and for a long time exliil)its marked alterations of liabits and ciiaracter, then suddenly or gradually becomes an inebiiate. There can be no doubt that inebriety originated in the traumatism following the diseases in these cases. Some special exciting cause favored its development, or possibly the injury done to the nerve-centers would only manifest itself in tliis way. The first causes are traumatic, following the diseases or lesions which take place, particularly notable in the complex range of psychical symptoms that are seen. The integrity of tlie organism and function has been impaired, and from this point disease and diseased ten- dencies are developed. These cases are found in every community, and of course do not all become inebriates, but like a large class of eccentrics are on the border line, or inner-circle shading into inebriety or insanity. A large number of persons engaged in the late civil war, who suffered hardship and mal-nutrition, became inebriates years after, following the psychical and physical traumatism received at that lime. The effects of commercial disasters, of bankruptcies, and panics in Wall street, can be seen in inebriate or insane asylums. In the asylum at Binghamton, New York, for inebriates, at one time were eighteen cases, whose inebriety could be clearly traced to a great money panic in Wall street, known as the " Black Friday." Many of these cases were purely from psychical traumatism, others were already in the dark circle close to inebriety, and needed but a slight cause to precipitate them over. Political failures are also fertile fields for the growth of inebriety and the action of psychical influences. Annually a large class after the close of a campaign find themselves literally inebriates, and if they have money go to water-cui-es, inebriate asylums, or to the far west and begin life again. The inebriety is TRAUMATISM IN THE CAUSATION OF INEBRIETY. 77 often of a paroxysmal or dipsomanical type, with free intervals of sobriety, that give renewed energy to the delusive hope tliac recovery will follow the bidding of the will. A class of moderate or occasional drinkers are always more susceptible to these influences than abstainers. This was marked in an instance where three men, two moderate drinkers and one abstainer, partners in business, witli equal capital, lost it all in one night. The abstainer recovered and resumed again, the moderate drinkers both drank to excess after, and died inebriates. It may be stated as a rule tliat moderate drinkers suffer more fre- quently from psychical shocks of every form, and are more likely to become inebriates from such causes. The inebriety that follovvs directly or indirectly from psychical traumatism, differs in natural progress and history from other cases. The physical degenerations are more pro- nounced, the heart and liver take on organic disease quickly, and the mental symptoms are prominent. In some cases the course of the disease is paroxysmal, and the mental degenerations are suspicious of what is called moral insanity. As in the following : A commercial traveler in good health, and a man of character, became an inebriate dating from a steamboat accident in whicli he was greatly alarmed, and barely escaped being both burned and drowned. When not drinking he planned and exe- cuted deceptions, cheated his employers, and engaged in a course of crime and villainy that was without shrewdness, and entirely foreign to all his past history. He was sent to prison and died from consumption. In another case, a merchant, after the onset of inebriety from the same psychical influences, suddenly became a gambler, and frequented the lowest places of this class. In the treatment of these cases, where the previous history has been concealed or not ascertained, the impulsive boasting and foolish prevarications, and efforts to cover up and live a double life by pretending to use all means for 78 DISEASES OF INEBRIETY. recovery, and steadily thwarting them, are often clear hints of psychical traumatism, which a more accurate history confirms. Want of space prevents us from illustrating this subject further. Any general study of inebriety will point out this factor of traumatism as prominent in many cases that are now unknown. The following conclusions may serve as a guide to other studies in this field, or as hints of the rich mines for clinical and psychological investigation awaiting future discovery. 1. The injury to the nerve-centers from psychical traumatism is the literal switch or point of departure from the main line, from which all subsequent disease and symptoms of change and perversion can be traced and studied. 2. The most prominent early symptom is exhaustion or neuraesthenia, which goes on progressively manifest in more complex deviations from health, and general func- tional disturbances. 3. This may explode into inebriety at once, or appear in moderate drinking, which will always end in inebriety. The type of this ci'aving will differ from others in the extreme mental degeneration which follows. 4. The prognosis and treatment will differ materially, depending on a knowledge of these facts, and will present indications that are absolutely necessary to know in the proper management of the case. CHAPTER IX. CAUSES CONTINUED. ADVERSITY, ETC., ETC. The disease of inebriety has in many cases a distinct prodromic stage of moderate drinking. In a certain num- ber of instances the disease never goes beyond this stage. Death follows from some intercurrent affection, always influenced by the state caused by alcohol. Moderate use of alcohol in a healthy man is always injurious, and is the initial stage of inebriety, whether it goes on to full devel- opment or not. All cases of inebriety are either preceded by tills early stage of moderate drinking, or appear sud- denly as the result of certain conditions more or less unknown. In the latter case injuries of all kinds are the most frequent causes. But in the former, the soil favorable for inebriety is already prepared, and slight exciting causes are sufficient to bring on full development. Adversity witli its mental depression and tendency to mel- ancholy, also general lowered mental and physical activity, are among the active causes which precipitate the moderate drinker into full inebriety. Clinical experience brings abun- dant proof of this statement. On physiological grounds it is clear that moderate drinkers have less resisting power to disease or change, which involves exhaustion of the nerve- centers, and changes of brain force. The use of alcohol has intensified the very state of debility which it is sup- posed to remedy, always masking and covering up the real condition. When a special demand is made on the system, this mask is thi"own off and inebriety appeal's. Clinically, a class of moderate drinkers who are intently 79 80 DISEASES OF INEBRIETY. absorbed in some pursuit or ambition, in which great interests are involved, become inebriates as a rule from adversity. They are neuraesthenic both from the use of alcohol and general perversions of tlie nervous system con- sequent upon over-work and mental anxiety. Hence, when the increased strain from the changed conditions of adver- sity comes on, alcohol is taken as a narcotic and gives relief. Another class of persons are noted clinically by their weak, exhausted nerve condition, and general instability of mind and body. Adversity frequently precipitates this class into inebriety. They are always predisposed to this affection, and tlie use of alcohol as a stimulant is so com- mon, and its effects are misleading, that they quickly fall into chronic stages of inebriety. The nerve-centers are in a condition of starvation from over-work and defective nutrition. Alcohol constantly increases tliis state, and hushes the agonized cries of nature for relief. In the observation of every one are found cases who have been moderate drinkers up to some great trouble or adversity, then become inebriates. Anotlier class are noticed of intensely nervous persons, who are not known as moderate drinkers, up to some period of profound shock or adversity, which changes and alters the entire mental or physical life. From this time inebriety springs up suddenly and generally progresses with great intensity. In the former case, adversity was the active exciting cause, kindling into energy conditions whicli may have been gathering for a long time. In the latter, it explodes a state of nerve exhaustion, in the direction of inebriety. Adversity, while depressing some men, destroying all energy and faith in any further exertion, has the opposite effect on others, rousing them to greater endeavors, which if buoyed up on alcohol, must fail in the future. Tiie ph3'sician's frequent prescrip- tion of alcohol in cases of debilit}'' following mental trouble and sorrow, is always full of peril to the patient. At this CAUSES CONTINUED, ADVERSITY, ETC. 81 time the danger of inebriety is very great, and cannot be over-estimated. Those who liave previously used spirits in moderation, should never have it as a medicine for any general disorder marked by nerve depression. Those who liave been temperate, and suffer from great physical and psychical disorder consequent on changes of external conditions, following adversity, cannot take alcohol without great danger of inebriety. Adversity has been recognized for a long time as preced- ing inebriety. The general fact has been often noted, that long-continued adversity in any community will produce more or less insanity. The same condition of adversity is followed more fre- quently by inebriety, which fact can be shown in the history of every community. Inebriety is a common sequel gnd physiological out- growth of adversity. All moderate drinkers are practically inebriates in the early stages, and liable any moment to develop extreme symptoms or stages of this disease. It may be said tliat the use of alcohol in all cases of nerve and brain debility, either from mental or physical depression, is dangerous and likely to bring on inebriety. Neurasthenia is rather the comparatively permanent exhaustion which is the result of prolonged over-strain, mental or physical, or botli, too little rest, insufficient or defective nourishment, long continued, until the substance of the nervous system, and often of the blood which nourishes it, is wasted or worn away far below healthy limits, entailing as a necessary consequence a correspond- ing /c^j'i" ^y /z^rz/^/t'Zf'^r and in most cases morbid exaltation of the seftsibility, not to speak at present of other important though auxiliary elements of such cases. Neurasthenia may be exhibited in the sphere of the mind as in weakness of thought, but especially weakness and vacillation of will, or in other words, loss of control and lack of decision ; in unduly excitable and unhealthy emotions, generally of a 82 DISEASES OF INEBRIETY. distressing or depressing character ; or in the sphere of the simple physiological activities, especially in feebleness and irregularity of muscular action ; exaltation of physiological sensibilities of any or all kinds, but especially reflex excita- bility ; the circulation of tiie blood is also, as a rule, unsteady and fluctuating, the action of the heart and small muscular vessels being easily disturbed by multitudinous causes, mental and physical. Then, again, it may be %^w- eial, extending to the whole nervous system, or it may be strictly localized, involving only limited parts of the nervous system, while other parts do not participate to the same extent or at all. Again, it may be hereditary or congenital, especially the former. People are born into the world daily, to begin, live, and end life, neuresthenic, or at least to be brought early into that state ; persons who have from the beginning weak, tricky nervous systems, either as a whole, or in some of its parts. On the other hand, there are persons to be met with, at all periods in life, and of both sexes, who are naturally healthy, as the phrase goes, who from prolonged over-exertion, mental or physical, or from being under a load of care or distress, or from prolonged loss of sleep or loss of appetite, or from insufficient food, or on the contrar}^ excessive waste, as in hemorrhages or diarrhoeas, or on account of some wasting disease, etc., and suffer a loss of balance in their nutrition, so that waste for a long time predominates over repair, to the exhaustion of the nervous energies, and a great gain in mobility, or " shakiness " of the nervous sys- tem, especially the nervous centers. It may form a disease (as it must be called) by itself, or it may and it does form a more or less conspicuous element in a great variety of diseased states, one which behooves you all to learn and detect and estimate. It is often overlooked or under-estimated, and often is the obscure and all-important element in cases that are widely different in appearance. It is the undertone in the picture CAUSES CONTINIJED, ADVERSITY, ETC. 83 in a vast number of cases of " heart disease," " brain dis- ease," even ** softening" of the brain, of hysteria, epilepsy, melancholia, neuralgia, paresis, mental weakness, feeble circulation, insomnia, etc. It prevails in all periods of life, and in both sexes. Instead of becoming less common, it is becoming more so, as time passes, and as people as a whole become more sedentary in habits, more intellectual in activ- ities, more engaged by occupation or by culture, so as to augment the sensibilities at the expense of the forces or power of the nervous system. I regard the refusal to take proper physical rest, when tired from labor, as one of the most important and power- ful in inducing a love for, and an indulgence in, the use of ardent spirits. Men work till they get so tired that they cannot wait to feel sensibly rested by processes of change going on in their systems from suspension of labor. They either want to work more hours than they are able to do ; or when they have done as much as they feel themselves at liberty to do, they are so tired that they cannot rest. They get rest, therefore, in artificial ways, by resorting to eating and drinking. Some get rested by drinking tea, others by drinking coffee, otliers by chewing and smoking tobacco ; but the great majority of tired people in this country — and the larger share of our people are tired — drink ardent spirits in some or oilier of its forms or preparations. They fall back on stimulants instead of the intrinsic vitalities of their bodies. They therefore are lifted up into false conditions. Accepting these as true, they keep on working till they be- come so functionally impaired as to induce positive inability to work longer, or they become so constitutionally depreci- ated as to be smitten with incurable disease. The hot waves wliich follow each other during the sum- mer months, register their duration and intensity in the police courts, station-houses, and hospitals of all large cities by the sudden increased number of inebriates who come under observation, A sudden rise of the thermometer 84 DISEASES OF INEBRIETY. brings more drunken men to the station-house, and more acute intoxication is noticed on the streets. Why this is so is not clear. Why sliould the nerve and brain debility of inebriates seem more easily affected by extreme heat ? Why should alcohol have more rapid action, causing pronounced narcotic effect? Why should the inebriate use spirits more freely at such times ? These and many more inquiries await an answer from the scientists and future investigation. One view of the subject should be practically recognized everywhere. First, the great danger of confining intoxicated persons arrested on the street in hot weather, inclose, badly ventilated cells; such cases are in great danger of heatstroke. Narcotized with alcohol, and thrust into close, stifling air — all the favoring conditions are present, and the person is found dead next morning in the cell, or in a state of deep stupor from which he dies later. The real cause was not the intoxication, but the heatstroke from the close air of the cell. Close, hot cells should never be used for the pur- pose of confining intoxicated men in hot w^eather. Second, in a number of cases, drinking-men suffer from partial sunstroke in the street or saloons, and are taken to station-houses, as simply drunken men. They are placed in cells, receive no care, and die. They may be temperate, and, feeling bad, take a glass of brandy for relief, fall into a state of coma, the real cause being the sun or heat-rays ; but from the alcoholic breath they are judged to be intox- icated and taken to the cell, only to have an increase of their injury and die. Another class of cases, far more common than is sup- posed, are those who, after a partial sunstroke, take a single glass of spirits, become delirious, and are called ** crazy drunk." They are roughly taken to the station, and, per- haps, hit on the head, with no other idea than that of will- fulness, and next morning are dead, or are taken to the hospital, and supposed to have meningitis, from which they CAUSES CONTINUED, ADVEKSITT, ETC. 85 die. The real cause was the policeman's club, and hemorr- hage from traumatism. Another class drink ice-water, or soda compounds, to excess, then, to relieve the distress from tiiese drinks, take brandy or whisky and become delirious. They are arrested, and thrust into a cell like the others, and if they do not have a heatstroke suffer from injury in their delirium by striking their heads against the walls. Policemen have no other standard except the alcoholic breath for determining the state of the person. An instance came under my observation, of a man, poorly dressed, who was overcome by heat and exhaustion, and was given a glass of whisky by a kind-hearted store- keeper. He became delirious, was taken to the station, and from thence to the hospital, where he died a few days later. The autopsy revealed a fractured skull and a ruptured artery, which came from the struggles in the arrest or self-inflicted injury in the cell. T/ii'rd, jndges who administer so-called justice to these poor victims, often assume that this sudden increase of inebriates demands increased severity of punishment ; and the wrong of arresting every one indiscriminately and sending them to station-houses is still further increased. Justice is outraged, and the burdens of the tax-payer increased, and the danger to life and property made greater by recruits to the dangerous classes — classes diseased and incapable beyond recovery, yet treated as law-abiding citizens and held responsible. Tlie medical men in every town should insist that all men arrested during hot periods for supposed intoxica- tion should come under medical care, and be examined carefully before they are thrust into cells. The community sliould be tauglit that the increased number of acute inebri- ates in hot weather points to ranges of physical causes that require study, and cannot be treated by policemen or police judges. Hot cells, in the ordinary station-houses, are 86 DISEASES OF INEBRIETY. sources of danger that should be avoided. The delirious or comatose inebriate who is placed in such cells over night, is practically murdered. The chances of escape from heat- stroke and traumatism are far less than the hope of recov- er^^ The skill to correctly determine the condiiion of these acute inebriates who are arrested in hot weathei", is far greater than in ordinary insanity, and should not be trusted to policemen and non-experts. Here is a field for tiie ambitious pliysician who would discover new ranges of physical causes, and point out methods of prevention of tlie greatest practical importance. Those who use alcohol in any form, either moderately or in excess, suffer more frequently from sunstroke and heat apoplexies. The fatality of these cases are greater than in those who are abstainers. The brain disturbances following are more serious and prolonged, and in many cases acute manias, various palsies, and dipsomaniac impulses are very prominent. Many of these cases occur in persons who are not thought to be other than moderate drinkers, particularly as they are seldom seen intoxicated, and, although at the time of the sunstroke may have the odor of alcohol about them, yet are not considered to be injured by spirits in any particular way. Tiiese cases suffer from sunstroke in two ways : either from the direct rays of the sun, or from the heat of close rooms or areas. In the latter case it occurs most frequently after sunset and before midnight. Very serious mistakes are frequently made in the diagnosis by physicians. A man will be found in the street in a state of coma, with an alcoholic breath, which, to a superficial observer, points to spirits as a cause. The real cause, sun- stroke, is not recognized, and death follows in a cell at the station-house, or in some other place, and nothing has been done to avert this event. In any case of coma found in the street in hot weather, the diagnosis of apoplexy from heat should be considered, irrespective of all alcoholic odors in CAUSES CONTIlSrUED, ADVERSITY, ETC. 87 the breath. A moderate and only an occasional user of spirits, feeling bad, took a glass of brandy, and soon after suffered from sunstroke and was taken to the station-house, where he had been ordered by a pliysician who made a diag- nosis on the odor of his breath alone. A clergyman who drank only wine at meals, and was' a red-faced man, was struck down by the sun soon after drinking some wine, and was taken to the station as a drunken man, the diagnosis being made on the same grounds. The physician should not forget tliat the odor of spirits, with a tendency to apo- plexy, excited by sunstroke or any other cause, and the circumstance of being found insensible in tiie hot sun, is sufficient to warrant a diagnosis of sunstroke, rather than that of coma from alcohol. In the second class, more difficulty follows. Thus, a man who has drank in moderation, or not at all, will be stricken down in a close room, and if the odor of alcohol is present he is supposed to be intoxicated. Cases of this kind are frequent in bar-rooms, and close, crowded tene- ment-houses in hot nights. The real diagnosis, heat apoplexy, is often overlooked. A man comes home from a hard day's work, takes a glass of spirits, and goes to some close room where the air does not circulate and radiation is imperfect, and soon after has an attack of heat apoplexy ; or, he may go to some close bar-room, and late in the evening be stricken down. These cases occur most frequently in large cities, and close, narrow streets, but will be found in all sections of the country where the conditions of heat and surroundings are favorable. The advice given in India to the English resi- dents and troops is very sensible and correct. First, to abstain from all alcoholic drinks during the hot season ; and, second, to drink large quantities of water, especially in hot days. With this are many directions about the care of the body, namely : to avoid over-work, pressure of 88 DISEASES OF INEBRIETY. clothes, bad food, and so on. Partial sunstrokes are more common where the person has a faint, attended with dizzi- ness, momentary loss of consciousness, followed by severe headache and great prostration. These. attacks have a very serious influence on moderate or excessive drinkers. Often it is the beginning of profound degenerations, which go on rapidly to death. Heat apoplexies are very intimately associated as causes of inebriety, and when occurring in inebriates, lead to the gravest results. The use of spirits in any form undoubtedly favors and predisposes to sunstroke ; and whatever the explanation may be, it is certain that he who uses alcohol has less vigor and resisting power to high degrees of heat. In the comparison of the histories of many cases of inebriety, certain ranges of fact appear in a regular order. Continuous chains of cause and effect run through all the events. What appears to be the free will of the victim is but a narrow channel along which he is forced by condi- tions which he cannot escape. Appeals to his feelings and reason are useless, for these faculties are unable to direct or control the progress of disease. Often the victim is uncon- scious that he has lost his power of control, unconscious of the march of events ; the steady disintegration of brain vigor and health, and never realizes it. Delusions of health and self-control become fixed as the disease goes on. The range of his mental powers steadily narrow and approach the animal in comparison, and are finally lost in a general dissolution. The agents exciting the emotions, and exhausting tlie nerve forces, and so causing inebriety, are everywhere present in the tremendous activities of our American civilization. The atmosphere is full of psychological germs, calcula- ted to infect the nervous system and produce disease. " Hopes and fears, appealing to the deepest motives of our nature ; political excitement, producing tumults of passion CAUSES CONTINTTED, ADVEKSITY, ETC. 89 and bitter feeling ; commercial waves of good and bad fortune, causing alternately intense joy and as intense disr appointment and chagrin ;" these are some of tlie dangers breaking up the healthy mental equilibrium and increasing the perils of every life. It is in this atmosphere that inebriety begins and goes to full development, standing out in lurid relief with our boasted civilization. CHAPTER X. INEBRIETY IN AMERICA AND ITS PECULIARITIES, ETC. Inebriety in America is more impulsive and precipitate than in other countries, the period of moderate drinking is less marked, and the average life of the inebriate is shorter. Among the many reasons for this are the tremendous activity and competition in the ordinary vi^ork of life, the intensity of living, the constant excitement and changes, filling every moment of time, calling out every energy, put- ting them in a constant strain, followed by want of rest, neglect of the healthy functions of the body, etc., etc. Add to this the constant practice of using the stron'gest alcohols at all times and occasions, and it will be seen that the average American must of necessity possess less resting power, and will fall a victim more readily to the action of alcohol. The effects of these influences are marked psychologic^ ally in the character of the inebriety seen in America. When under the influence of alcohol the average American is full of delusions of speculation for wealtli, power, and political achievement ; his ideas flow in a channel of great events, and great schemes for the welfare of the nation and ilie race ; he is rarely a wife-beater or avenger of personal worngs, but may be prominent in a mob to destroy some great evil, or foremost to break up some old order of events which are supposed to be blocking the wheels of progress. The inebriate American will always be found in the van of every new project in politics, social science, religion, and 90 INEBEIETY IN AMERICA. 91 business, and, like Colonel Sellers, is buoyed up with the stimulating hope of " There's millions in it." The records of courts rarely exhibit brutal crime among inebriates who are Americans, but great schemes of companies, frauds, and stupendous swindles, for money or notoriety, etc., etc., are common among this class. The increased con- sumption of all forms of alcoholic drinks, beyond the average gain of population, give indications of the in- crease of inebriety. This is confirmed by the court records of drunkenness in all the large cities and towns, and also from comparative evidence of the mortuary sta- tistics which point to a rapid increase of those diseases which are most common in inebriates : namely, insanit}', paralysis and acute affections of the heart, kidneys and lungs. It may be said, beyond all doubt, that inebriety in America terminates most frequently in acute organic affections of the body. Another fact of great interest is apparent to the psychological student, namely, that ine- briety in America moves in waves and currents, with a decided epidemic and endemic influence. This can be traced to the rapid increase of drunkenness in towns and cities, and after a time a reaction sets in, and a marked decline follows ; the latter is seen following the temperance agitation and revivals. In some cases this is traced to special causes, such as financial depression, great social changes, etc. ; at such times moderate drinkers become pronounced inebriates and weak, nervous organizations fall into inebriety. This increases up to a certain point, then from some unknown psychical force declines, and a revival of temperance efforts follows, with a decline of inebriety to a minimum. These waves and inebriate storms that sweep over large circles of country are always followed by intense revivals of temper- ance interest, and are fields of the most fascinating psycho- logical interest yet to be studied. Alcholic inebriety among American women is undoubt- edly becoming less every year. Although it is more 92 DISEASES OF INEBRIETY. covered up tlian in oilier countries, yet its presence is apparent in the demand for narcotics, and the sale of beer and wine by grocers, also in the divisions of saloons into general and family entrances, with separate rooms for each. Among the better classes of women wine and spirits are less openly used, and social drinking more rare. The same is true of all classes, except those of foreign birth, who still cling to the old custom of public drinking. The same gen- eral causes govern women that are noticed among men, only varying in degree ; hence, while women do not use alcoholic spirits as men do, undoubtedly they consume all forms of narcotics in excess of other classes. Their peculiar sensitive organization demands narcotics as a relief from the strain and exhaustion to vyhich they are constantly subjected, and this is a source of great peril to the future of the American race. In this brief outline of the nature and character of inebriety, it may be said that American inebriety is more often a pronounced form of brain and nerve degeneration, and that it comes from well marked physical conditions, largely controlled by social and psychical states peculiar to America. Its symptomology more nearly resembles that of insanity and general paralysis ; its course is in waves and currents ; its progress is shorter ; and among women the use of narcotics is more prevalent than of other forms of alcohol. At the recent international congress, held in London under the auspices of the Society for the Study of Inebri- ety, brief reference was made to certain factors which con- tribute to make the study of inebriety in America specially serious and urgent. Although there are abiding factors the world over, in America we have elements to study which are peculiar and unique. Bs' America is meant the American Republic, the States and Territories bounded by the seas, the lakes and the gulf. Here sixty millions of people are placed under mEBRIETT IN AMERICA. 93 those physical, ps3xhic, political and social conditions which combine to make life more vividly intense atid exacting than anywhere else on tliis planet, and therefore are more sus- ceptible to the malady of inebriism. This region luis been called " the intemperate belt." " Inebriety may be said to have been born in America and has developed sooner and far more rapidly than elsewhere ; and like otiier nerve maladies is especially frequent here. It is for this reason, mainly, that asylums for inebriates were first organized here." Here also the total abstinence soci- eties of modern days began. Why ? because of the abnor- mal nerve sensibility which the feverish rush of life here has developed, a physiological condition, that will not tolerate stimulants. Dr. Beard says that it is a greater sight than Niagara, which is presented to a European coming to this land, to behold an immense body of intelligent citizens, voluntaril}'- and habitually abstaining from alcoholic beverages. " There is perhaps no single fact in sociology more instructive and far reaching than this ; and this is but a fraction of the general and sweeping fact that the heightened sensitiveness of Americans forces them to abstain entirely, or to use in incredible and amusing moderation, not only the stronger alcoholic liquors, but the milder wines, ales, and beers, and even tea and coffee. Half my nervous patients give up coffee before I see them, and very many abandon tea. Less than a century ago, a man who could not carry many bottles of wine, was thought effeminate. Fifty years ago opium produced sleep, now the same dose keeps us awake, like coffee and tea. Susceptibility to this drug is revolutionized." Dr. Beard makes the ability to bear stimulants a measure of nerves, and asserts that the English are of "more bottle- power than the Americans ;" that it is worth an ocean-voy- age to see how they can drink. A steamer seat-mate poured down, almost at a swallow, a half tumblerful of whiskey with some water added. He was a prominent minister in 94: DISEASES OF INEBRIETY. the Established Church, advanced in years, yet robust. He replied to the query, " How can you stand tiiat ?" that he had been a drinker all his life and felt no harm. Tlie same relative sensitiveness is shown in regard to opium, tobacco, and other narcotic poisons. The stolid Turk begins to smoke in early childhood, when seven or eight ; everybody smokes, men, women, and little ones, yet the chief oculist in Constantinople says that cases of amau- rosis are very few. A surgeon whom I have known. Dr. Sewny, of Aintab, after 3''ears of extensive practice in Asia Minor, has yet to see the first case of amaurosis or ambly- opia due solely to tobacco. But Americans cannot imitate Turk, Hollander, and Chinese. Heart and brain, eyes, teeth, muscle, and nerve are ruined by these vices, yet the frightful fact remains that laterally the importation of opium has increased 500 per cent.! The "tobacco heart" and other fatal effects of cigarette smoking are attracting the attention of legislators as well as physicians, and the giving or selling this diminutive demon to youth is made in some places a punishable offense. Physical, psychic, political, and social conditions com- bine in the evolution of this phenomenal susceptibility. Nowhere, for instance, are such extremes in thermal changes. I have seen in New England a range of 125", from 25° below to 100^ above, in the shade. The year's record at Minnesota has read from 39° below to 99'^ above, a range of 138". Even within twenty-four hours, and in balmy regions like Florida, the glass has shown a leap from torrid heat to frosty chill. No wonder then the greatest fear of some is the atmos- phere ! They dreadeS to go out to face Arctic rigor or tropic fire, and so get in the way of staying indoors even in exquisite weather of June and October. They make rooms small, put on double windows, with list on the doors, and build a roaring furnace fire in the cellar, adding another of bright anthracite in the grate. The difference INEBRIETY IN AMERICA. 95 befween tliis liot, dry, baked air within, and the wintry air without, is sometimes 80°. It is estimated that the differ- ence of temperature inside and outside an English home averages 20", and tliat within and without an American dwelling is 60°. The relation of this to the nervousness of the people is apparent. The uniform brightness of American skies favors evapo- ration. The Yankee is not plump and ruddy like his moist, solid British brother, but lean, angular, wiry, with a dry, electrical skin. He lights the gas with his fingers, and fore- tells, with certainly, the coming storm by his neuralgic bones. Hourl}'^ observations were conducted for five years with Captain Catlin, U. S. A., a sufferer from traumatic neuralgia in care of Dr. Mitchell. The relation of these prognostic pains to barometric depression and the earth's magnetism was certified beyond doubt, and was reported to the National Academy of Science, April, 1879. Even animals in the Sacramento valley and on the Pacific coast are unwontedly irritable while the north desert winds are blowing, and electricity seeking equilibrium, going to and from the earth. Fruits, foliage, and grass, towards the wind, shrivel. Jets of lightning appear on the rocks and sometimes on one's walking stick. "^wl psycJiic and social factors cannot be ignored. Some- one has said that insanity is the price we pay for civilization. Barbarians are not nervous. They may say with the Duch- ess of Marlborough that they were born before nerves were invented. They take no thought of the morrow. Market returns and stock quotations are unknown ; telephones and telegraphs ; daily newspapers, with all their crowded col- umns of horror and crimes, are not thrust upon them ; and the shriek of the steam engine does not disturb their mid- day or their midnight sleep. Once a day they may look at the sun, but they never carry watches. This bad habit of carrying watches is rebuked by a distinguished alienist, who says that a look at one's watch, when an appointment 96 DISEASES OF INEBRIETY. is near, sensibly accelerates the heart's action and is correl- ated to a definite loss of nervous energy. Every advance of refinement brings conflict and conquest that are to be paid for in blood and nerve and life. Now, it is true, that watches are occasional!}' seen in England. Sun-dials are not in common use in Germany and Switzerland. But the "American Watch " is an institu- tion. Not the Elgin, the Waterbury, or any particular watch, but the worry and haste and incessant strain to accomplish much in a little time — all this symbolized in the pocket time-piece, is peculiarly American. It was an Amer- ican who, at Buffalo, I think, wanted to wire on to Washing- ton. When told it would take ten minutes, he turned away and said, "I can't wait." He now uses the Edison telephone, and talks mouth to mouth with his friend. Dr. Talmage says, "We were born in a hurry, live in a hurry, die in a hurry, and are driven to Greenwood on a tro.t !" The little child, instead of quietly saying to its playmate "Come," ner- vously shouts, "Hurry up !" You cannot approach the door of a street car, or railway carriage, but what you hear the same fidgety cry, " Step lively !" Said a New Yorker to me, " I am growing old five years every year." Can such physical bankrupts, whose brains are on the brink of collapse, bear the added excitement of drink? The gifted Bayard Taylor was but one of thousands who burned a noble brain to ashes in a too eager race of life. Reviewing sixteen months he notes the erection of a dwelling-house, with all its multitudinous cares, the issuing of two volumes of his writings, the preparation of forty-eight articles for periodicals, the delivery of 250 lectures, one every other day, and 30,000 miles travel. The same story might be told of other brain-workers who never accepted the "gospel of rest." The emulous rivalries of busitiess life and the speculative character of its venture cannot be paralleled elsewhere. The incessant strain they impose increases mental instability. INEBRIETY IN AMERICA. 97 Bulls and bears, pools, corners, margins, syndicates, and other" words that are dark, and tricks that are vain," rep- resent the omnivorous passion for gambling. Millions may be made or lost in a day. No one is surprised if a Wall Street panic is followed by suicides. Legitimate business may, by its methods, exert a per- nicious influence on the nervous system in still oilier ways, as for example, in tlie depressing influence from specializa- tion of nerve function, as indicated by D!\ Jevy'ell, where one keeps doing one petty thing monotonously year after year and so sterilizes mind and muscle in every other direction. Turning to educational systems in America, we see how unphysiological they are, and calculated to exhaust the ner- vous energy of youth, many of whom have inherited a morbid neurotic diathesis. Of twenty-seven cases of chorea reported by Dr. Hamimond of Bellevue Hospital, eight were " induced by intense study at school." Dr. Treichler's investigations as to " Habitual Headache in Children," cover a wide field and show that continental communities suffer from similar neglect of natural laws. Here it is more notorious. Not to dwell on these points, we may say that the stimulus of liberty is a productive cause of neurasthenia in America. It is stated that insanity has increased in Italy since there has been civil and religious liberty guaranteed. Kpost hoc is not always Sl propter hoc. But it is obvious that the sense of responsibility which citizenship brings ; the ambitions awakened by the prospect of office, position, power, and influence ; the friction and disquiet, bickerings and wranglings, disappointment and chagrin that attend the struggles and agitations of political life, do exhaust men, and more in a land where opportunities for advancement are abundant as in America. While writing these words, news is received of the sudden death of a prominent New York politician, comparatively young, directly traceable to disappointment in carrying out a scheme on which his lieart 98 DISEASES OF INEBRIETY. was set. Chagrin acted like a virulent poison on a system already unstrung by the severe political struggle in which he was defeated. Multitudes contract the full malady of inebriism under the continued pressure of these political campaigns. The patient of a friend of mine had, for two years, been kept in working order. He was living, however, on a small reserve of nerve force. A few days before election, he was drawn into a five minutes eager discussion, and became entirely prostrated, more exhausted tlian by months of steady work. Other nations have their measure of liberty and aspira- tions for social and political eminence to gratify. But nowhere have men the exliilarating possibilities of position, wealth, and influence, that this republican community offers. The history of the last half century, as related to this fact, reads like a romance. But liberty, like beauty, is a perilous possession, and it lias been truly said " the experiment attempted on this continent of making every man, every child, every woman an expert in politics and theology is one of the costliest of experiments with living human beings, and has been drawing on our surplus energies for one hun- dred years." Final Iv, American life is cosjnopolitati. A curious observer noted nine nationalities in a single street car in New York, one day. I repeated the fact to a few of my students who were riding with me througli those same streets. Looking over the ten or dozen passengers on board, one of them at once replied, " Well, here are five nationalities represented here." In one aspect, these importations, particularly English, German, and Scandinavian, are compensative and antidotal. We may hope, with the author before quoted, that " the typical American of the highest type will, in the near future, be a union of the coarse and .fine organizations ; the solidity of the German, the fire of the Saxon, the delicacy of the American, flowing together as one; sensitive, impressible, INEBRIETY IN AMERICA. 99 readily affected through all the avenues of influence, but trained and held by a will of steel ; original, idiosyncratic ; with more wiiiness than excess of strength, and achieving his purpose not so much through the amount of his force as in the wisdom and economy of its use." This hope may be realized in the future and in the highest type of American manhood. It is a bright, optim- istic view of things, but we have to do with the present and the evils of society as they exist. We have to face the fact that our civic life is growing at the expense of the rural ; that our cities are massing people by the hundreds of thousands, among whom, on the grounds of contiguity, association, and psychic sympathy, evil influences become more potent to undermine the welfare of society ; that we have to encounter in America the drink traffic in its belligerant aspects, as nowhere else, not only politically and financially organized most thoroughly, but ready it would seem to use fraud, violence, or assassination if other means fail, and that we have anarchism stirring up discontent and firing the passions of the desperate classes, who understand liberty to mean license, equality to be the abolition of all the diversities of position and property which intelligence, temperance, and industry have made, and will make, to the end of time. We have had a practically unrestricted importation of the refuse population of Europe. Of every 250 emigrants one is insane, while but one of 662 natives is insane. Add to all these facts the conditions of American life already enumerated as related to the development of neuroses, par- ticularly inebriety, and we have material which makes the study, as was stated at the start, serious and urgent. CHAPTER XI. PREVALENCE OF INEBRIETY AND ITS MORTALITY, ETC. Notwithstanding all the advances of civilization and intelligence, and the increasing temperance agitation and effort, the drink evil, or inebriety, is one of the most threat- ening, ominous perils to all social progress and development of to-day. Some idea of its extent may be obtained from the fol- lowing satistics. In 1891 over five hundred tliousand per- sons were arrested in this country charged with being drunk and disorderly, crazed from the effects of alcohol. Nearly twenty per cent, had committed crime of petty character while under influence of spirits. These facts furnish some approximate estimate of the extent of inebriety in this country. It is reasonable to infer that if this number of inebriates have come under police surveillance in one year, at least a third more using alcohol to excess, have escaped legal notice. The statement that there are fully a million persons in this country who are, continuously or at intervals, using alcohol and opium to excess and poisoning tlieniselves, is not an extravagant or improbable one. Of course the mortality from this, both directly and indirectly, is excessive, and the oft repeated assertion of sixty and a hundred thousand deaths a year from alcohol is, after all, only a minimum statement. The physical and mental degeneration, the unsanitary conditions of living and surroundings, predisposing to pau- perism and exhaustion, all strongly favor disease, accident and early death. Dr. Kerr, of London, after a very exhaust- 100 PEEVALENCE OF INEBRIETY. 101 ive Study of the mortality reports of the United Kingdom, concluded that the annual mortality from inebriety could not be less than one hundred and twenty thousand. This statement was confirmed by Mr. Wakel}'', a well known coroner, who found in fifteen hundred inquests held in one year, nine hundred of them were from inebriety. The conclusions of the late Mr. Neilson, tlie eminent actuary, are equally striking. He found that while ten temperate persons from 15 to 20 years of age die, eighteen inebriates of the same age die. Between 21 and 23 years (inclusively) 51 of the intemperate of inebriates die for every 10 of the temperate. Between 31 and 40 about 40 die. In the first group the fatality is raised 80 percent., in the second over 500 per cent., and in the third 400 per cent. Mr. Neilson calculated the cliances of life as follows : A temperate adults chances of life is at 20 over 44 years, an intem- perate 15/^ years ; at 30 a temperate 36/^, an inebriate 13.8 years ; at 40 a temperate's 28.8 years and an inebriates 11.6. In the mortality of Great Britain only between 1400 and 1500 deaths are noted as arising from alcohol annually. But it is well known that these figures are no criterion of the actual number of deaths from inebriety. The present system of death certificates makes it easy to evade the real cause of death, and put down some intercurrent affection or condition that occurs just before death takes place. This is done to save the feelings of friends and relatives, and cover up some state which would only add new pangs of sorrow by exposure. A new system of registration is demanded to ascertain accurately many of such mortality facts. Tiie Harvian Society of London have studied this topic and reached similar conclusions, sustaining Dr. Kerr's esti- mate of one hundred and twenty thousand deaths yearly in the United Kingdom from inebriety. In this country the late Dr. Parker showed from some comparative facts that inebriates had an average of ten years, after the full devel- 102 DISEASES OF INEBRIETY. opment of the drink curse. Dr. Harris indicated that twenty per cent, of all deaths in large cities were due to inebriety. All the life insurance companies find the mortality which dates from heart and kidney disease associated with the use of alcoholics, and many of them refuse to take risks on any one but total abstainers. It is computed that for every death from inebriety there are at least fifty cases of illness. Associated with this are premature deaths, starvation, acci- dents, violence, neglect, until tiie loss and suffering becomes appalling in magnitude and severity. Tlie recent outbreak of cholera, with its extreme fatality, recalls the mortality amonginebriates which has character- ized the march of this and other epidemics in modern times. We select illustrative statistics of the ciiolera epidemic of 1832. In St. Petersburg, out of 10,000 deaths only 145 were known to be temperate ; in Moscow, only 2 out of 6,000 cases were temperate. This fact so alarmed the citizens that nearly all the population ceased to use alcohol ; of 30,000 victims in Paris, nearly every one used alcohol, in some form, to excess ; nine-tenths of those who died in Poland, were of this class. In some towns every inebriate was swept away. In Tififlis, every drunkard died. In the Park Hospital of New York city, only 4 persons were temperate in 200 fatal cases. In Albany, there were only 7 out of 326 fatal cases who were not inebriates. In the late epidemic of yellow- fever in the South, the percentage of victims among inebri- ates was nearly as large. Tiiese are not extraordinary facts, but follow, naturally, tlie degeneration produced by alcohol, and are readily explained by the low vitality and lessened power of resistance to toxic forces and agents present in every inebriate. Most unfortunately, this con- dition is not realized by either the patient or friends until it is too late. The continued use of alcohol keeps up the delusion of strength and vigor ; but with the onset of dis- ease all is thrown off, and only the physician and surgeon can realize their hopeless condition. CHAPTER XII. INEBRIETY AND CONSUMPTION :,, ITS RELATION AND CONNECTION. Any one who studiously watches the evolution and dis- solution of families, some of whose members are addicted to alcoholic excess, must be struck with the frequent occurrence of pulmonary phthisis among tiiem. So on the other hand, it is no less astonishing to find the latter disease suddenly appearing in families who are absolutel}'' free from a phthisical history, and who seemingly live amidst the most healthful surroundings. Why these two conditions should be so closely associated, if in consonance with the current belief, the one is a nervous, and the other a strictly pulmonary disease, is not very clear. The following is an attempt to an elucidation of this intric- ate problem, in which I shall endeavor to show that these two apparently isolated phenomena are naturally interchangeable with each other, and that like two diversi- fied islands cropping out above the surface of the ocean without exposing their connection beneath, they find their common bond of union in a disordered state of the nervous system. In order to make this subject as practical and as intel- ligible as possible, I shall at the very outset endeavor to prove the intimate association between alcoholism and phthisis, how one link may change place with the other in the chain of vital persistence, by citing a number of living, illustrative examples. The first ten of these cases liave been culled from the extensive experience of Dr. Crotlieis, 103 104 DISEASES OF INEBRIETY. and have been placed at my disposal through his kindness ; while the remainder have been obtained from various other sources. Case I. J. B., aged 42 years, began the excessive use of spirits after the death of his wife. He was a merchant, temperate, prosperous, and a man of character. He became a steady drinker, and was practically intoxicated all the time. After an attack of delirium tremens he was placed under my care. During the four months while under treatment, he was alternately depressed and elated. He complained of wandering pains, and changeable appetite, as well as of spasmodic periods of coughing. A few months after he left me, he relapsed and continued to drink until he died a year later. His mother and two sisters died of consumption. His father died from injury, but his grandfather was asthmatic, and used spirits to excess for years. One uncle on his father's side died from excess of drink, and another one died of consumption. One uncle died from phthisis after many years of drink excess. His grandfather on his mother's side drank more or less all his life, and died from some rheumatic trouble. Case II. B. A., aged 35, a mechanic, began to use spirits for insomnia and general debility, and finally became a periodi- cal inebriate. He was under treatment for six months, and recovered. His father, grandfather, and two uncles, died of consumption. His mother was liysterical, and his grand- mother on his mother's side died of some lung trouble. One brother died from chronic alcoholism, and a sister is a drug- taker. Case III. C. H., age 48, an army officer, began to drink during the late war. He is now a dipsomaniac, with dis- tinct free intervals of three months. His mother died of consumption two months after his birth, and his two sisters died of the same disease. His father's family is temperate, but several members have died of consumption. His grand- IKEBEIETf AND CONSUMPTION. lOS father on his mother's side was a sailor, and drank to excess at times. Case JV. D. P., age 38, a farmer. His drinking seems to date from a nervous shock following the burning of a barn by lightning. His two brothers are chronic inebri- ates, one sister is a morphine taker, and the other uses both spirits and drugs to excess for all kinds of imaginary evils. On his mother's side, a grandfather and three aunts and one uncle died of consumption. His mother is still living. His father died of pneumonia, and his grandmother on his father's side died of consumption. Case V. E. J., age 31, a clerk of inferior mental and physical development, began to drink at puberty. Con- sumption has been the common family disease of both parents. On his mother's side both consumption and inebriety have been common. On his father's side con- sumption alone has prevailed. Case VI. P. O,, age 28, is withont business, and drank from infancy. He is now a chronic inebriate and has had delirium tremens. His father and two uncles died of con- sumption. His mother is a woman of wealth and fashion, and she lost her mother and one sister from consumption. Case VII. M. B., a lawyer, 54 years old, who began to drink at fifty from no apparent cause. His father and grandfather died of consumption at fifty years of age. Case VIII. D. T., age 38, a conductor, began to drink after an injury to the spine. A brother, who was injured at the same time, died of consumption. The mother and a sister, the grandfather, and grandmother, on his father's side, all died of consumption. Case IX. D. B., 24 years old, and without business, began to drink at puberty, and is now a chronic inebriate. Both parents died of consumption. His grandfather on his father's side, and two uncles on his mother's side, died of the same disease. Case X. A. H., 34 years old, a physician, took morphia 106 DISEASES OF INEBRIETY. for malarial poisoning, and then used alcohol to great excess. His mother and tiiree uncles on his father's side died of consumption. His older brother became an inebri- ate at about thirty years of age, and one sister is in Colo- rado to prevent consumption. Case XI. {Quarterly Journal of Inebriety, Oct., 1888, p. 390.) "George Ulmercame from England in 1798 and settled at New Haven, Conn. He was a harness-maker, a beer- drinker, and after middle life drank rum to excess, until death at sixty-one years of age. His wife was a healthy woman, and lived to eighty years of age. Eight sons grew to manhood and married. Six of them died of consumption under forty-five years of age. One v^^as killed by an accident, and one died from excessive use of spirits. Two daughters grew up and married ; one died of consumption, the other in childbirth. They left four children ; two were inebriates, and the others were eccentric and died of con- sumption. Of the children of the eight sons only ten grew up to manhood. Four of these drank to excess and died. Three of the six remaining died of consumption, and two others were nervous invalids, until death in middle life. The last one, a physician of eminence, has become an inebriate and is under care at present. He is the only sur- viving member of all this family. The male members of this family were farmers, tradesmen, and men of more than average vigor in appearance. They married women (so far as can be ascertained) without any special liereditary his- tory of consumption or inebriety." Case XII. Father was an inebriate until after he w;is forty years old, at which time a cardiac affection developed itself from which he ultimately died, but which had the power of restraining him from exercising his morbid appe- tite. His brother was a drunkard too. Tliree of his sons became confirmed alcoholics, one daughter died of phthisis, and another son died of general paralysis. Case XIII. Father violent, an alcoholic, and a libertine. INEBKIETY AND CONSUMPTION. 107 Mother is very nervous, and died of cancer of the uterus. Many of patient's relations are drunkards. Her brotlierand sister died of chest disease, and another brotlier is always ill, and coughs a great deal. She was admitted May 3, 1879. One month previously she had a chill, rigors, and feverish- ness, which confined her to bed for four days ; then she began to cough, and had two copious haemoptyses. She sweats profusely at night, is losing flesh, and in a word has all the symptoms of pulmonary phthisis. Physical examin- ation shows evidence of tuberculosis of both apices. The histories of these cases give the most unmistakable proof that alcoholism and phtliisis are not mere coinci- dences, but that they have a relationship so intimate that one may be converted into the other. The problem arises, however, as to the channel through which alcohol produces phthisis ; for if these two conditions are interchangeable, it is obvious that they must possess a common physiological basis, and this I believe resides in the nervous system. I have elsewhere (to which I beg to refer the reader) given good reason for believing that pulmonary phthisis is prin- cipally nervous in character, and by considering it as such, tlie natural association between the two diseases is at once established. For whatever else may be said of the action of alcohol, it is pretty generally understood that it possesses a special affinity for the nervous system, and that it produces its principal ravages in the body by operating on this, and by preference on the peripheral nervous tissue. Dr. James Jackson, in this country, and Dr. Wilks, in England, were I believe the first to point out this form of disease, and they called it alcoholic paralysis. It has since then received the more appropriate name of alcoholic neuritis, and it is charac- terized in its early stages by numbness, tingling, hyperses- thesia in the extremities, and later on by anoesthesia, par- alysis of motion, loss of knee jerk, quickened pulse, short- ness of breath, and frequently by pulmonary embarrass^ ment. The brain and spinal cord remain comparatively 108 DISEASES OF INEBRIETY. normal. The morbid changes occurring in the peripheral nerves under the influence of alcohol are parenchymatous and interstitial, or in other words they are confined to the nerve substance itself, or to its investing membrane. As a rule these changes occur together, tiie latter in many instances depending on the former, but frequently one exists exclusively of the other ; especially is this true of the degeneration of the nerve fibre itself. It being established, then, that alcohol has the power of producing degeneration of the nerve fibres, it does not require a reckless fiiglit of fancy to see how, by operating on the same tissue, it may bring about that peculiar destruction of lung substance known as pulmonary con- sumption. Degeneration of a nerve implies degeneration of the organ which it supplies witii sensation and motion. Thus, degeneration of the sciatic nerve is followed by impairment of sensation and motion in the muscles and other textures of the leg — a condition which is almost con- stantly present in chronic alcoholism, and degeneration of the pneumogastric nerves is just as naturally followed by disease of the lungs, heart, stomacli, and all the other organs supplied by them. This is no more than we may legitimately anticipate ; for it has been amply proven that division of, and protracted pressure of tumors, aneurisms, etc., on the pneumogastric nerves are capable of calling forth all the destructive lesions of pulmonary phthisis. The following cases will serve to illustrate the close anatomical and physiological association of chronic alco- holism and phthisis, as well as other destructive pulmonary charges with degeneration of the vagii, and of the respira- tory center (the latter of which practically amounts to the same thing), and with that of the peripheral nerves. The ditficulty encountered in this research has not been so much in obtaining an abundance of material in which phthisis was evidently the direct result of alcoholic abuse, as it has been in finding the records of cases possessing all the points INEBRIETY AND CONSUMPTION. 109 which I desire to emphasize in this paper, viz.: the coexist- ence of pulmonary disintegration, alcoliolism, and nerve degeneration, well brought out by a tliorough post mortem demonstration. Case XIV. Drs. Oppenheim and Siemerling. Male, addicted to alcoholic excess, was received in hospital Jan. 26, 1886. He was weak and stiff, but had no pain. At the end of the same month he became delirious, and also paretic in both legs and arms. Death occurred in March of the same year. On section it was shown that the heart was normal, and that he had pneumonia ; microscopically it was proven that the radial, peroneus, and saphenous nerve had undergone degeneration. Not stated whether the vagii were examined or not. Case XV. Drs, Oppenheim and Siemerling. A female, ^gs 45 years, suffering from chronic alcoholism, was received Dec. 26th, and died on the 28tli of the same month, in the year 1885. On section there was found chronic exud- ative pleurisy on right side, as well as a caseous broncho- pneumonia and tracheitis. The great saphenous and super- ficial peroneus nerves liad undergone parenchymatous degeneration of a medium degree. No otlier nerves were examined. Case XVI. Dr. T, Dejerine. Female, age 46, a hard drinker, suffered from paralysis of both upper and lower extremities. Had a pulse of 150-160, and her heart sounds were normal. Her death was caused by pneumonia. Sec- tion showed parenchymatous neuritis of the cutaneous and muscular nerves, as well as of both vagii in the cervical region. Case XVII. Prof. Schultze. Male, 39 years old, devel- oped diabetes insipidus in 1882, but had been feeble since childhood. He used alcohol greatly to excess in his younger days. Some time after the year 1882, he began to suffer from nystagmus, trembling in the arms, perversion of sen- sation (paraesthesia) in the legs, and from thoracic constric- 110 DISEASES OF INEBRIETY. tion. In 1886 he became subject to marked attacks of dyspnoea, and death was caused by paralysis of respiration. Section : Degeneration of medulla oblongata and spinal cord, as well as that of tlie root of the vagus and hypo- glossus. No account of the post mortem appearances of the lungs is given, but it is evident that these organs were implicated in the morbid processes, since death was pro- duced through pulmonar}"" paresis. Case XVIII. Striimpbell. Male, aged 47 year, a potator, was received November 25, 1881. His frame is large and powerful. Both of his arms hang helplessly by his side ; hands cedematous, skin and tendon reflexes wanting ; legs weak and powerless ; pulse, 124 ; temp. 38.2° ; deglutition and power of speech impaired ; after a while oedema of lower extremities, cough, diarrhoea, dyspnoea ; bronchial rSles, paralysis of diaphragm, and death, Feb. 13, 1882. Section: Marked tubercular phthisis of both lungs. The radial median, crural, and sciatic nerves were degenerated very decidedly, and Dr. Striimpbell believes that the phrenic and vagii were also involved, but he failed to examine them closely. Case XIX. Drs. Oppenheim and Siemer.ling. Male, 26 years old, a potator, was received in the Charity Hospital Jan. 17, 1881, on account of delirium tremens. He com- plained of headache, giddiness, and formication in the legs. He improved and was dismissed, but was received again on July 28, 1883, on account of marked disturbances in the nervous system. He now suffered from complete impo- tence, lancinating pains and rectal tenesmus. In August, he became subject to polydipsia and polyuria; on the 12th of December, there ivas dullness in left supra clavicular fossa, and infiltration of both apices and tubercle bacilli were found in the sputum. He gradually sank and died in August. Microscopic examination showed degeneration of the medulla oblongata, and of all the peripheral nerves which were examined. INEBKIETT AND CONSUMPTION. Ill Case XX. Dr. Oswald Vierordt. Male, 30 years old, much addicted to alcoliol, and without a syphilitic history, suffered since Marcli, 1884, witli piercing, lightning pains in the lower extremities, as well as with weakness, unsteadi- ness, and formication in the same. He also developed tubercular phthisis and died the following March. Section : extended tuberculosis of the lungs and degeneration of the columns of Goll, medulla oblongata, and the cervical and dorsal portions of the spinal cord. Case XXI. Mr. Siiarkey {^British Medical Journal, 1888, April 21, and Journal of Inebriety., Jan., 1889, p. 67) related a case of alcoholic paralysis of the phrenic, pneumogastric and other peripheral nerves before, and presented specimens of the same to the Pathological Society of London. The patient was a female and addicted to the excessive use of alcohol. She suffered from weakness in her legs, numbness and cramps, and was incoherent in speech. Respiratory sounds were harsh, and in a few days after admission had a rigor, which was followed by a temperature of 102.8^, severe attacks of dyspnoea, paralysis of the diaphragm, and difficulty in swallowing. Respiration 40 per minute, and average pulse rate 140. Spitting of blood supervened, the lung apices began to break down, and she died after having been under observation nearly one montii. Section : tuber- culosis of botli apices and inflammatory changes in the piirenic, pneumogastric, and popliteal nerves. In these examples we have proof that pulmonary phthisis can be produced through the toxic action of alcohol on the nervous system. This is unquestionable in four of the cases, and in so far as demonstrating the mode of tlie action of alcohol on the human lungs is concerned, it is equally true of the other cases ; for I think it is pretty well estab- lished that phthisis is but the legitimate offspring of any persistent catarrhal state of the lungs, and that clironic bronchitis and catarrhal and broncho-pneumonia, are bat 112 DISEASES OF INEBRIETY. the milestones marking the pathway along which the dis- ease travels to its final destination. Such then being the relation between alcoholism and pul- monary phthisis it is very readily understood why these two diseases should so frequently change places in different members or generations of the same family, and why they are so often associated with various other nervous dis- orders. Moreover, alcohol having the potency to produce phthisis de novo in the human subject, either directly or through hereditary influence, or both, as we have seen, it must, in view of its past and present widespread abuse in civilized countries, be a tremendous factor in maintaining the ranks of the hundreds of thousands of those who are annually slain by this terrible malady. To this and to no other conclusion do the premises of this paper point, and if one had the inclination to moralize on this subject it would be very interesting to inquire why the North Ameri- can Indian, and other savages, were practically free from pulmonary consumption until they came in contact with tlie white race ! When we connect the facts that alcohol and syphilis are the greatest curses which the Indian has acquired from his white civilizer, with the evidence which has been brought forward in this as well as in another paper on Syphilitic Phthisis, I think it must be obvious that these two causes are largely responsible for sowing the seeds of pulmonary phthisis among these people. CHAPTER XIII. EFFECTS OF ALCOHOL AND BEER ON MENTAL FUNCTIONS AND THE BRAIN. The effects of a single dose of alcohol differ widely in different individuals, and this lies at the root of all scientific inquiries into the matter. The variety of the effects on the mental faculties of different brains is also extreme. This indicates such different qualities and susceptibilities in dif- ferent brains as regards this agent, that it makes the whole question of the effects of alcohol a most complicated one, not to be explained by a few unqualified assertions. In reply to the question, What are the normal effects of alcohol on the mental forces of the brain ? the scientific man must reply. What k4nd of brain do you mean ? and it is only by a careful study of the qualities, the tendencies, and potential- ities of different brains, that we can answer the first question properly. We need to study the mental qualities of the brain at different periods of life, in the two sexes, in differ- ent temperaments and constitutions, in different races, in different states of healtii and vigor, and with reference to the hereditary tendencies of the organ ; for all these things influence the effects of one single small dose of alcohol. So we find, looking from the point of view of the amount of the doses, the effect is very different. There is, I believe, no other agent known which differs so greatly in different in- stances in the dose needed to produce the same effect on the mental powers as a dose of alcohol, and herein again we find that there must be the greatest difference in the power of resisting the effects of alcohol in different brains. Tak- 114 DISEASES OF INEBRIETY. ing tlie lower animals, that difference is exceedingly small, an ounce of alcoliol given to a dozen dogs of tlie same size will practically have the same effect on them ail ; but an ounce given each to a dozen men has not only the most dif- ferent effects in the mental faculties it stimulates, as we have seen, but in the amount of the effect it causes. Some brains are exceedingly sensitive to very small quantities ; other brains have the power of resisting or tolerating alco- hol in a wondrous degree, this being an innate quality quite apart from the effect of the use and custom. These differ- ences are so great as to compel us to conclude that there are enormous inherent disparities in human beings in this respect, and this is no doubt one of the very great dangers in the use of alcoliol. So we also find at the various periods of life, ordinary small doses of alcohol have very different effects. In a child the effect is extremely great, in a boy or girl it is also great, but it is not so great in a growing adoles- cent. In the two sexes there are also considerable differ- ences, the female having less resisting power, her brain being unusually much more susceptible to 'the influence of this agent. Looking at different races, the differ- ence of effect of the same dose is also extremely great There are some savage races that are so subject to its influ- ence that a very small dose indeed — half an ounce — will have greater effect on them, than two or three ounces will have on an ordinary European. The psychological, the mental effects of small doses of alcohol are therefore exceed- ingly various, and we have not yet discovered the precise qualities of brain which caused these differences. We can not tell beforehand which brain will be susceptible to its effects, and which will not. Looking at the matter next from a point of view of the effects of a much larger dose, these will be found much more uniform. The effect, instead of being stimulating, is then narcotic, and we have a deadening, paralyzing and temporary arrestment of the EFFECTS OF ALCOHOL ON MENTAL FUNCTIONS. 115 mental functions of the brain in every individual if a suffi- cient quantity is taken. But here we find much variety in the way tlie result is arrived at, when carefully studied. In one person we have this paralysis, this deadening taking place first on the intellectual faculties, in another on the emotional, in another on the propensities, and in another on the power of motion. We see a certain kind of mental degeneration of a slight type, which results in those who habitually take an amount of alcohol that is to them excessive. This slow but quite marked type of mental degeneration a doctor of experience soon comes to observe in his patients ; and others a certain change mentally, morally, and bodily, in the man who is taking more than is good for him. The expression of his face and eyes — those mirrors of the mind — you see has changed, and for the worst. The mental condition of the man is lowered all round, and especially one effect is noticed, that his higher power of control is lessened, I am safe in saying that no man indulges for ten years in more alcohol than is really good for him, without this kind of degeneration being observed, and that although during these ten years he was never once drunk, we find him psychologically changed for the worse in his independence of mind, in his spontaneity. After a man has passed forty, such changes are very apt to be faster, and more decided. We see such a man's work and his fortune suffering, but we dare not call him either a drunkard or dissipated, because, as a matter of fact he has never been drunk, and never intends to be drunk. Whether this degeneration takes place soon or late depends upon inherent resistive capacities of his brain cells. In some individuals the resistive capacity against alcohol is so great that for years they may indulge in its excessive use without this degeneration taking place to any great extent, but in other instances we have it very i-apidly developed indeed. Some men pass into a premature old age and become old at fifty, when they ought to have lived on and been young 116 DISEASES OF INEBRIETY. men up to sixty, and this merely owing to tlie excessive use of alcohol. Memory and the power of thinking are affected, but you see the lowering most in the finer faculties, the tastes, the more delicate perceptions of things, and the force of character. This is an effect which, I believe, is especi- ally to be observed in men who have used their intellectual powers constantly and vigorously. We often see this effect on the brains of men in our profession, of medicine, at the bar, and even among the clerical profession, in a very marked degree, without their owners having been once drunk. In such persons, their mental powers having been greater to begin with, and with a finer edge on them, you notice in a more marked way this degeneration in its progress. This, I may say, is the least marked mental effect of alcohol taken, not so as to produce drunkenness, but taken in greater quantity than the physical constitution of the brain can stand over a long period. In some brains a very small quantity indeed, taken daily, will produce this degen- eration. For some years past a decided inclination has been apparent all over this country, to give up the use of whisky and other strong alcohols, using as a substitute, beer and bitters and other compounds. This is evidently founded on the idea that beer is not harmful and contains a large amount of nutriment ; also that bitters may have some medicinal quality, which will neutralize the alcohol it conceals, etc. These theories are without confirmation in the observations of physicians and chemists where either has been used for any length of time. The constant use of beer is found to produce a species of degeneration of all the organism, profound and deceptive. Fatt}'^ deposits, dimin- ished circulation, conditions of congestion, and perversion of functional activities, local inflammations of both the liver and kidneys, are constantly present. Intellectually, a stupor amounting almost to paralysis arrests the reason, pre- cipitating all the higher faculties into a mere animalism ; EFFECTS OF ALCOHOL ON MENTAL FUNCTIONS. 117 sensual, selfish, sluggish, varied only with paroxysms of anger, that are senseless and brutal ; in appearance the beer-drinker may be the picture of health, but in reality he is most incapable of resisting disease. A slight injury, severe cold, or shock to the body or mind, will commonly provoke acute disease, ending fatally. Compared with inebriates, who use different forms of alcohol, he is more incurable, and more generally diseased. The constant use of beer every day gives the system no time for recupera- tion, but steadily lowers the vital forces ; it is our observa- tion that beer-drinking in this country produces the very lowest forms of inebriety, closely allied to criminal insanity. The most dangerous class of tramps and ruffians in our large cities are beer-drinkers. It is asserted by competent authority that the evils of heredity are more positive in this class than from alcoholics. If these facts are well founded, the recourse to beer as a substitute for alcohol, merely increases the danger and fatality following. In bitters we have a drink whicii can never become gen- eral ; but its chief danger will be in strengtliening the dis- ordered cravings, which later will develop a positive disease. Public sentiment and legislation should comprehend that all forms of alcohol are more or less dangerous, when used steadily ; and all persons who use them in this way, should come under sanitary and legislative control. CHAPTER XIV. CLIMATIC PERIOD — DIAGNOSIS OF INEBRIETY AND STUDY OF SOCIAL STATISTICS. " There is a natural tendency in our very life to find a settled cliannel in which its forces may flow. So conscious are we in the earlier periods of our adult life of the exist- ence of strong and opposing passions and tendencies, that we are apt to accept as an axiom the common expression that ' character is not formed until forty.' Physical factors are all the time at work to develop and mature what is in, and of us, and it is not until maturity is reached that a definite and uniform channel is wrought out and established. This age of maturity is not and cannot be determined according to a uniform rule, but just as the sexual instinct has its time of beginning and ending, so other elements have a similar history." Again, " There comes a time in the course of one's life when the forces that have been engaged in structural repair and waste come as to a stand-still, and consult together as to which shall be dominant in the future. Some of the organs may be said to rest entirely after a certain age ; rest by a cessation of function, and become atrophied also ; some, that do not rest absolutely, undergo a modification of functional activity. It is at this slack-water period — at the middle of life — when the molecular deposits in the organic structure are different in quality than formerly, that we look for a different product." The craving for drink is not a craving of childhood, it does not usually declare itself until the demands on the nervous system begin to be exorbitant, and its terminal ii8 CLIMATIC PERIOD. 119 period comes with as much certainty as does its initial stage. That terminal period is the climacteric period. Many years ago Dr. Parrish called attention to this thought, and urged those who had opportunity to observe to note the period of life when the largest number of reform- ations or cures of inebriety were accomplished, and stated that he believed they would be found between the ages of forty and fifty. Subsequent observation has confirmed his view. ''^Between these ages especially do recoveries that are spon- taneous occur, and statistics show that by far the greater number of persons first exhibit the alcoholic proclivity between the ages of fifteen and twenty-five, and though unable to verify the statement by figures, he was convinced that the allowance of twenty-five years of use will, in most cases, close the drinking career, either by exhaustion of the desire, or by the fatal teimination of the individual life. He thought it will be found also, that when inebriates have lived beyond the middle period of life, so as to attain the three or four-score limit, the commencement of the drink- ing career was considerably later in life than the average period named." Dr. Mason from a careful study of six hundred cases in this country and one hundred and fifty-two treated in Eng- land, found the greatest liability to be from 30 to 40, and after 45 or 50 the decline in the drink curse was very rapid. Dr. Kerr found that this period was from 55 to 60. Other observers agree that a time occurs in each case where the possibility of the subsidence of the drink curse is favored by such a period. In the early stage of inebriety the diagnosis of the dis- ease is extremely difficult. There are no physical signs upon vvhicli the examiner can rely. He must draw all the facts on wliich to form his opinion from the applicant him- self or his friends, neither of whom are likely to conscien- tiously confess tlie truth. Tlie applicant himself, as a gen- eral rule, is ignorant of tlie fact of disease, and will account 120 DISEASES OF INEBRIETY. for his personal habits in some other way. Fortunately, if he is not tlioroughly posted in regard to tlie symptoms of the disease, he will unwittingly betray the trutli by the revelation he will make of his habits. First of all, it must be borne in mind that the inebriate is a chronic deceiver, and cannot be depended upon to tell the truth. His testimony is not to be relied on even under oath when there is a motive to deceive, unless there are corrobo- rating circumstances to sustain it. Impairment of the moral perceptions is one of the first symptoms of the disease, and is also an obstacle to a correct diagnosis. An inebriate never sees himself as others see him. If he did there would be more hope in his case. The heredity of the applicant should be carefully inquired into. No man is a good risk if he uses alcohol in any form, or to any extent ; if he has an inheritance of inebriety, insanity, epilepsy, or any other form of neurasthenia, no matter what a man's present habits of indulgence may be, he will not be able to adhere to a temperate use for any great length of time. It is a recognized fact that three-fifths of all the persons who use alchoholic liquors between twenty and thirty become inebriates ; and the inference that per- sons of such a heredity who indulge in alcoholic stimulants will become inebriates, amounts to almost a certainty. Careful inquiry will elicit the fact that such persons use alcoholic drinks because they like them, because the effect, if not the taste, is agreeable, A man may like claret because it relieves his thirst, or he may like beer because it gives him an appetite ; or he may indulge, in a company of friends, for the sake of sociability or hospitality, and it may not be considered a symptom of inebriety. But when it is evident that the man drinks because the specific effects of alcohol are especially agreeable to him, he must become a total abstainer, or it will be only a question of time when he will become a confirmed inebriate. CLIMATIC PERIOD. 121 A positive dislike or aversion to the use of alcoholic drinks at certain intervals, and a strong desire for them at other periods, is often a characteristic of the inebriate diathesis. Wlien an admission is made of an occasional indulgence to excess, it is very important to know why it is occasional, or what tlie occasion is. If it is periodic, or at somewhat regular intervals, it must be regarded as evidence of disease. An abnormal desire for alcoholic drinks, however mani- fested, is an evidence of disease. If the diseased condition has once been establislied, it is always liable to return ; and tlie percentage of exceptions in favor of permanent cure is so very small that a period of abstinence for one or more years does not make the applicant a safe risk. Men who have had alcoholism, dipsomania, or delirium tremens, and have reformed to such an extent as to be total abstainers, for any considerable period, go down very rapidly if they return to their old liabits. Under such circumstances their prospect of life is very low ; not more than four or five years at most in the majority of cases. All cases of inebriety may be classed as persons of unde- veloped, degenerate, and disordered minds. Tlie first class, the undeveloped, represents all grades of defective, retarded growths, sometimes seen in external conformations of head and body. Grades of ancestral defects and brain failures, seen in faulty acts and thoughts. The second class, of degenerate brains, are those who are retrograding both in mind and body. Such cases frequently date from illness, injuries, shock, diseases of all kinds, and diseases of old age, and of the nerve centers. The third class, the disor- dered brains, are those who from ill-health, bad conditions of living and surroundings, have developed inebriety. Such cases cannot bear the strains, drains, or any extreme circumstances, which tax the energies and vigor of the body. In all these cases, inebriety starts from unknown 122 DISEASES OF INEBRIETY. States and exciting causes, and these marked physical conditions are both primary and secondary. Inebriety is always disease and degeneration, and the fact often disputed is, can this disease be traced in any uniformity of symptoms or progress? Dr. Jackson has clearly pointed out, that all disease follows a regular retrograde march, which can be outlined and studied as clearly as growth and development. Inebriety is no exception to the rule. The frequent instances where inebriates in apparent possession of good judgment, go away and drink to great excess, displaying a degree of forethought and premeditation fully characteristic of all the ordinary events of life, are often very confusing to the ordinary observer. When the drink paroxysm comes all unexpectedly upon the victim, in some unforeseen state and circumstance, and he falls, it is dimly apparent that he is suffering from some unstable or diseased brain state, which has burst out from the application of some exciting cause. But when the paroxysm is anticipated and prepared for, and all the surroundings are made subservient to this end, when every facility to procure spirits are increased, when money is secured and business arrange- ments are made in view of this coming paroxysm, the con- clusion most commonly reached by all non-expert observers is that it is deliberate vice and wickedness. When the his- tories of a number of these cases are studied and compared, they are found to be well-marked cases of reasoning insan- ity, with drink paroxysm. These paroxysms are the acute attacks — the deliriums wliich expend thejnselves like storms that gather and burst — and are preceded by long periods of rest. A typical case is that of a banker, who is a man of excellent judgment in all business and social matters. He will prepare for a week or ten days in advance for a drink paroxysm. He is a temperance advocate, yet he will display great cunning to conceal the approach of this "spell." He will become very active in his temperance efforts. His friends realize his danger, and try by every CLIMATIC PERIOD. 123 means to help him, but find tliat all their efforts are turned to aid him in concealing it. He will not begin unless he can find some way to conceal his presence while the parox- ysm is on him. When his friends were vigilant, he has been kept sober for a week or more, but witii the first opportu- nity he disappears, and all tiieir work has been thwarted by his cunning. In another case, the most deliberate reason- ing and planning will mark the paroxysm. In another case, all at once he will rush away and diink in the most suicidal and insane way, only giving as an excuse some real or fancied injury or trouble. This deliberation and cunning is a symptom of mental unsoundness, and is most obviously reasoning insanity, and will be recognized when these cases are better understood. Dipsomaniac and periodical inebri- ety very soon became reasoning maniacs, dangerous bC' cause they are unknown and misunderstood. In a study of social statistics, nativity^ sex, age, tempera^ ment^ climate, occupation, custom, and social conditions, are import- ant factors in the etiology of alcoholic inebriety, outside ot the well-known causes preceding or accompanying dis- ease or injury and heredity, and also, to a certain extent, are to be taken into consideration in the treatment of all cases of inebriety. Nativity of tiie 4,663 cases under care at Fort Hamilton, N. Y., was as follows : United States, 3,186 ; Ireland, 826 ; England, 203 ; Scotland, 77 ; British Possessions, 73 ; Ger- many, 109; other nationalities, 44 ; not recorded, 145. The United States naturally compose a large majority, as we find in asylums of other countries inhabitants of those countries as inmates will be in excess of all others ; but we must acknowledge that the nervo-sanguine tempera- ment of the American is peculiarly susceptible to the evil effects of alcohol, and that, other things being equal, the average American would sooner succumb to inebriety than his transatlantic brother. Ireland takes the lead among foreign nationalities. Next in order we have England, 124 DISEASES OF INEBRIETY. Germany, and Scotland ; tlie lesser nationalities occur in in- significant proportions, and do not call for special comment. As a matter of racial importance I cannot recall a single instance of acute or chronic alcoholic mania in the negro among the several thousand inebriates who have passed under my notice during a period of nearly twenty-four years. In reply to a series of questions, Dr. Edwards, of Rich- mond, informs me " that the negro is rarely the subject of chronic mental or nervous disease arising from alcohol, although it is rare to find a negro, male or female, who does not drink. Alcoholic liquors are preferred, and yet the laboring negro, as a rule, is not a drunkard." He attributes this to the out-door life, simple habits, and low grade of nervous organization of the negro. Climate. — As to the influence of climate on inebriety, we have not any special statistics to show, but it is a popu- lar impression that the inhabitants of low levels, especially near the sea-coast, are more apt to be intemperate tlian the dwellers on the higher plateaus, table-lands, and mountain- ous districts. The influence of certain barometric condi- tions, dependent upon atmospheric changes, in influencing and producing certain conditions of the nervous system, is familiar to all who have made this subject a special study. It is also a well-known fact that in malarious districts the depressing effects of the malarial cachexia are counteracted by the free, habitual use of quinine, strychnine, coffee, and other nerve stimulants, among which alcohol predominates. No one will dispute the fact that an unhealthy, enervating climate is more apt to produce intemperance and conse- quent inebriety, than a climate having just the opposite characteristics. Climate, undoubtedly, is one of the factors in the production of inebriety, as it is of other diseases. Sex. — There were 4,084 males and 579 females. The Fort Hamilton Asylum is intended more especially for males, hence the small proportion of females. It has no CLIMATIC PEKIOD. 125 provision for females of the better class ; the female inmates were from the middle and lower classes of society, but the inference must not be drawn that inebriety does not prevail among females of all classes, or that the above is a fair relative proportion of the inebriates of botli sexes. In this countiy, undoubtedly, the male inebriate far exceeds in numbers female inebriates. But this is not universally the case. In England and Wales the habitual inebriate females already convicted to the habitual inebriate males already convicted are as three to one. In England, espe- cially among the higher classes of society, inebriety pre- vails to a greater extent among females than in the same class and sex in the United States. Social Conditions. — The married male inebriate exceeds in numbers the unmarried male inebriate. There were 2,098 married, 1,744 single, male inebriates ; and especially does the married female inebriate in far greater proportion exceed the unmarried female inebriate. There were 401 mar- ried female inebriates and only 48 single female inebriates. Must we conclude that, other things being equal, the married life predisposes to inebriety > It would seem so, in the case of females at least. The married female has a much greater strain upon both her mental and physical constitution than the unmarried. A fact substantiated in the reports of our Asylum further shows, that unmarried males are more fre- quently subjects for re-admission than the married ; that is, that they are more apt to relapse. The reverse is true in regard to females. Married females are more apt to relapse than unmarried females. The latter are not apt to relapse ; if they do, it is the exception to the rule. The spinster then, is the most temperate member of society. There were 242 widowers and 130 widows also recorded. Approximation of Ages. — The ages of the majority of the cases treated were from 20 to 60, the greater proportion from 30 to 50, and of these considerably over one-half were between 30 and 40 years of age. Below the age of 20 and 126 DISEASES OF INEBRIETY. above the age of 60, comparatively few. The oldest patient w^as 73 years of age, and the youngest 18 years. We must conclude that the great majority are of that period of life which is the most effective for usefulness and attainment under normal conditions. In other words, alcohol cripples and handicaps the majority of inebriates at the most useful period of life. Another fact is, that inebriates may excep- tionally, but do not as a rule, attain to a long life. About one in 385 of inebriates, whom we treated, reached the age of 70 years. Occupatio7t. — Let us now consider the relation of in- ebriety to occupation. Imagine a community of 4,663 adult inebriates, embracing every trade, employment or profes- sion. Excluding 234 males who had no occupation and 562 females, 275 of whom were unemployed, and the balance either domestics or housekeepers, we liave about 3,867 males who were variously occupied, representing two hundred trades, professions, commercial, mercantile, or agricultural occupations. We find directly engaged in the liqtior business 71 bar- tenders and 51 liquor dealers. The indoor trades exceeded the outdoor trades. Among those engaged in the outdoor occupations, inebriety seemed to affect most those whose business especially exposed them to irregular hours and inclement weather, — teamsters, cartmen, coachmen, carmen, conductors, drivers. One hundred such are recorded. Tiie next in frequency were butchers (45) ; next stone-cutters (28) ; next plasterers (26) ; next coopers (19). The other occupations being at or below the latter figure, and run- ning at or about the same average or percentage. Among in-door occupations we find painters (121) in the majority. The painter handles alcohol, turpentine, etc. ; his occupa- tion is not a healthful one ; he is apt to contract diseases incident to it, as turpentine poisoning, lead colic, and ner- vous diseases arising from lead poisoning, as wrist drop, or paralysis of the extensor muscles, etc. CLIMATIC PERIOD. 127 Next in order come printers (58) and pressmen (58). Long hours, extra work, night work, and an employment that demands great rapidity, and probably more mental and physical strain than the average occupation, may account for the fact that the printer and the pressman take the second place. The other trades are in the following order : Shoemakers (45), plumbers (39), tailors (38), hatters (34), tinsmiths (31), waiters (28), photographers (27), carpet-weavers (22), glass- blowers (21) — the remainder of the in-door trades were at or below 20, The greater part of the various occupations were from mercantile or commercial life. At least 1,200 or 1,300, or about one-third of the entire number belonging to one or the other of the above classes in the following order : Clerks (565), merchants (283), bookkeepers (100), salesmen (152), agents (78), brokers (44), the balance being made up of canvassers, contractors, railroad officials, bankers, pub- lishers and superintendents, etc. In agricultural occupations we note, farmers (34), and gardeners (15). Professions. — Four hundred and seventy-seven, or about one-eiglith of the whole number, belonged to the profes- sions, as follows : Physicians (115), lawyers (m), engineers (58), druggists (43), journalists (39), artists ('32), students (21), reporters (19), clergymen (10), actors (9), the balance being in small proportion, architects, accountants, actuaries, notaries public, chemists, assayers, army officers, dentists, editors, etc. Why physicians are in excess of other professions is due to the fact that they lead very arduous lives, both physical- ly and mentally, with irregularity as to sleep and diet, rest and recreation ; but there is another fact also, the physician would be more likely to appreciate and avail himself of asylum privileges for the treatment of his inebriety than any of the professions. 128 DISEASES OF INEBRIETY. In considering the various avocations the usual average relation of the occupation or profession to a normal con- dition of society must be considered. In this way only can we get at the fact as to wliether any one calling exceeds the other in a tendency to lead to inebriety. Results of Treatment, etc. — Total cases, 4,663 ; still under treatment, 1,283 I total cases discharged and to be accounted for, 3,380 ; doing well, 1,465, 43 per cent. ; lost sight of, 662, i9>^per cent. ; unimproved, 555, i63^ per cent. ; re-ad- mitted, 556, idYz per cent. ; died, 81, 2>^ per cent. ; trans- ferred to otiier institutions, 61, 2 per cent. Doing well. — By this we mean the patient is restored to society, to his business and social relations. Exclusive of death and transfer, the percentage will be nearer 45 per cent. It must also be considered that the inebriate on an average is not brought to us for treatment until after his Inebriety has existed ten years, his system broken down, and oftentime the subject of incurable disease, the result of his inebriety or some disease or injury with which his inebriety is compli- cated, and which may have preceded and been the cause of it. Again, not only do inebriates apply at a late period for treatment, but onl}'' about one-quarter of those who do apply remain over six months, while three-fourths remain at periods varying from one to four months, and the large majority less than the legal limit of three months, so thai if we were to apply the same rule that is applied to other diseases which are submitted to us to be cured, that is, hav- ing the patient brought to us at a reasonable period after the disease tendency has manifested itself, and having also the patient remain under our care a reasonable length of time for treatment as each case may demand, it would be easy to see that our ratio of cures would be 75 or 80 per cent., instead of 43 per cent, as they now are, which is neverthe- less a good showing considering the disadvantages we have had to contend with. We are confident that in the future, CLIMATIC PEKIOD. 129 under proper conditions, at least three-fourtlis of the in- ebriates treated in our asylums will be cured. Thirty-six per cent, were lost sight of, or unimproved, but this does not mean they will not be heard of again ; a cer- tain proportion will return to our institution, and of tliese a number will be cured. Some of our most successful cases are those wliich have been in the asylum at different periods under treatment. Of the balance, some will die, others will move away, otiiers go to similar institutions elsewhere located. We shall not make any comments as to deaths except to call attention to \.\\^ remarkably small percentage, which is about equally divided between those who died outside of the asylum and those who died in the asylum. Some 6i were transferred to other insitutions — 30 to the lunatic asylum. We observe the tendency of inebriety toward insanity. The great majority of inebriates caVry unevenly-balanced minds ; they are on the verge of insanity all the time, and not unfrequently pass over the line. In any inebriate asylum it would be safe to assert the large majority of inebriates, at least for the first few weeks after their entrance into the asylum, are in a mental condition that, to say the least, is not normal. The above 30 trans- fers were marked cases of lunacy, acute or chronic mania, which were not suitable for an asylum of our character. The moral effect and the law of association forbid that the inebriate of weakened mind and body should be associated with insane persons. The tendency of every inebriate is that way, and such association would only precipitate the event. This is the principal argument against the incarcera- tion of insane persons and inebriates in the same institu- tion, although there are other arguments equally effective, A certain proportion of persons were brought to the asylum suffering from various diseases or infirmities that rendered them unfit subiects for our asylum. Of these, some 31 were transferred to hospitals or other institutions. We have thus given a few general observations, result- 130 DISEASES OF INEBRIETY. ing from a study of these special statistics. We have not by any means exhausted tlie subject, but we trust we liave added some points of interest and importance, not only to the etiology of inebriety, but also some indications for its more successful treatment. CHAPTER XV. ALCOHOLIC DELIRIUM AND ASSOCIATED CONDITIONS. The existence of certain specially dangerous and hyper- acute forms of delirium tremens has been known and recog- nized by many writers since the days of Magnus Huss, but the first distinct description of this class of cases in which an attempt at their differentiation from the ordinary type was made, seems to have been that of Delasiauve, of his so-called superacute form in 1852. In his cases, however, the distinctive symptom of fever was absent, and it was left for Magnan, in 1873 and 1874, to describe as a distinct variety, his cases of febrile delirium tremens. Although the cases which I am about to report do not agree in all respects with those related by him, I have ven- tured to make use of the title of febrile delirium tremens for them also. One of the predominant symptoms, perhaps we may even say their most striking cliaracteristic, was the presence of fever, and in many points they closely resemble the cases of Magnan. Moreover, there can be little doubt that the different varieties of delirium tremens shade imper- ceptibly into each other and that they are all acute mani- festations of chronic alcoholism modified in their symptoms by the constitution of the patient, his condition at the time, the existing complications and various other attending cir- cumstances. The presence, however, of so important a symptom as fever, affords, in our opinion, a sufficient ground for placing those cases in which it exists to any marked degree, in a separate category from the ordinary simple febrile cases. 131 132 DISEASES OF INEBRIETY. Since, after as thorough an examination as possible of tlie voluminous literature of delirium tremens, we have found no carefully reported cases of this character, since those of Magnan, we feel justified in bringing these to tlie notice of tlie profession more especially as we believe tliat there are certain considerations connected with them of considerable importance both to the specialist and perhaps even more to the general practitioner. A full description of the case is given, of which the fol- lowing is a summary : In this case we have a man of thirty-two, with a distinct predisposition to mental disease, and addicted for a consid- erable period to the excessive use of alcohol. Having con- tinued the abuse of the stimulant after, at least, two attacks of delirium tremens, he finally, four weeks before entering the hospital, and probably much earlier, is perceived to act in a strange manner, to have temporary lapses of memory, and hallucinations of sight and hearing. On entrance, he is found to be much in the condition of a patient recovering from a severe attack of delirium tremens — weak, with decided tremor of face and hands, and mentally affected, unable to realize his surroundings. Very shortly , /ever was detected, and, instead of improving, he grew rapidly worse. The general weakness increased, and was accompanied by v-ery marked and constant subsultus tendinum, and by con- tinual plucking at the bed-clothes. The tongue was cracked, dry, and parched, and the general condition suggested that of typhoid fever. Mentally, he likewise became worse, hav- ing constant, rapidly changing hallucinations, many of them terrifying and horrible, but many also, and the proportion of these increased as the disease progressed, of a not unpleas- ant character. He constantly imagined that he saw friends and acquaintances, who spoke and chatted with him. He talked aloud much of the time, often starting up suddenly and answering some subjective question. This condition of things continued for a montli, being varied by periods of ALCOHOLIC DELIRIUM. 133 semi-coma, when he could with difficulty be roused to answer questions. The fever ceased at one time, to recur later. At the end of a month his strength had improved, and there were no acute symptoms remaining. From this time his mental condition improved until he left the hospital, only to grow worse afterwards, and to necessitate a still longer treatment before final recovery. In this case, there is little doubt that there existed in the beginning that condition of chronic alcoholic poisoning so carefully described by Lentz, under the title of chronic hallucinatory alcoholism. This, possibly due to the with- drawal of stimulants, passed soon into an acute febrile con- dition, recurrent, and lasting about a month, to be followed in its turn by the ordinary hallucinatory alcoholic insanity. The second case was that of a liquor-dealer, thirty-two years of age, a native and resident of Boston. One of the patient's uncles was insane for a time, and at the Worcester Asylum for six months. No record of any other mental or nervous affection in the family obtained. Patient had been healthy, except as follows : He has been a constant drinker for two or three years, and at times has drunk very heavily. Last autumn, he had several epi- leptic fits, and he has fallen down stairs several times. Two weeks before entrance, he stopped the use of alcohol entirely for five days, but then resumed. He was at this time placed under the care of a physician, as he had begun to have hallucinations of sight, and was rapidly growing worse. Finally, being inclined to be violent, he was brought to the hospital. This case was similar to the others. In both the preceding cases we have to deal with patients in whom, we may presume, a certain tendency to mental disease exists. One had already himself been in an asylum; the other had had a near relative in one. In both, the existing affection was undoubtedly induced by addiction to the excessive use of alcohol. The more prominent and 134 DISEASES OF INEBKIETY. noteworthy symptoms in these cases may be resumed as follows : (i) Tlie duration of the disease, followed in both cases by recovery, in connection with (2) the peculiar tem- perature, rising at times to 102^ or more ; (3) the great weakness of the patient, especially in the earlier stages ; (4) the typhoidal appearance ; (5) the constant subsultus tendinum, and the plucking at the bed-clothes ; and (6) which is less uncommon, the long duration of the pecu- liar form of delirium vvh'ich in the beginning, precisely resembled that of delirium tremens, but continued for weeks, with a gradual change to less terrifying hallucin- ations. I will not enter here into the question of the differentiation of these cases from typhoid fever and other diseases, but will merely say that in the cases related tliere did not exist any of the more diagnostic symptoms generally seen in typhoid fever, except the general typhoid-like condition of the patient, and that in both cases the course of tlie temper- ature was unlike that usual in typhoid. The medico-legal importance of such cases as these seems to me considerable. The question to decide is whether the patients were actually insane, and likely to remain so for a considerable period of time, or whether the condition was a more or less temporary one, and the patient had a fair chance of recovery. In the first case, the actual question to be decided was whether the patient should at once be committed to an asylum, or whether it weie advis- able to wait ; in the second, whether the patient was likely to remain in his actual condition so long that it was right and advisable that his property should be put in trust. In both cases the decision was in the negative, and rightly so. I cannot help feeling, for these reasons, that it is very important that this class of cases should be early recognized, not only by specialists, many of whom have, undoubtedly, opportunities for observing them more or less often, but also by the general practitioner, into whose hands they, in ALCOHOLIC DKLIEIUM. 135 the beginning, almost always fall. All the cases of this character that I have seen, or have been able to find accounts of up to the present time, have either been fatal within a few days, or have ended in recovery. At any rate, if death does not occur within ten days, the prognosis is more favorable than one would be led to suppose by simple consideration of the duration and character of the symptoms. In regard to the pathology of these cases, although data sufficient to justify a decided opinion are wanting, certain facts bearing on this subject may be mentioned. Without entering into detail in regard to the pathological changes of the nervous centers and their envelopes in alcoholism, we may refer to a few general results. Four- nier states that autopsies after aaite alcoholism in man show most commonly the following lesions: " cerebral conges- tion, more or less intense ; meninges injected, veins and vessels of the pia mater gorged with blood, cerebral sub- stance dotted with points, roughened (sable), and, on section, permitting the escape of fine drops of blood ; sometimes, also effusion of serum into the meninges." In chronic alcoholism we find two classes of lesions in these organs ; the one, which may fairly be classed as acute, though the result of clironic changes, comprising, for example, hemorrhages, and perhaps some effusions ; the other class, the subacute and chronic. Audhoui, writ- ing in 1868, says : "There is no need, I think, of insisting on the form that the nutritive trouble affects in the nervous centers, thickening of the meninges, the production of false membranes on the cranial dura mater, adherence of the pia mater to the cerebral cortex, hypergenesis of the neuroglia, fatty degeneration of the nerve-cells, of the capillaries, etc. ; all this is perfectly well-known." In regard to tlie superacute form of delirium tremens we may mention two varieties, the " forme suraigne " of Dela- siauve, and the delirium tremens febrile of Magnan. Delasiauve's form is described by Lentz as follows ; 136 DISEASES OF INEBKTETY. *' The forme suraigne of Delasiauve is remarkable par- ticularly for its violence, its agitation, the intensity of the delirium and the gravity of the general condition. The nervous activity is prodigious ; the patient has neither respite nor repose, no part of his body is free from move- ment ; liis face bloated, red, even violet, is contorted through the quivering of the muscles ; his eyes roll in their orbits ; his skin is hot and burning, is moist with a profuse and sticky sweat, whicli sometimes emits an alcoholic odor. The tongue may preserve its natural moistness ; more often it is dry along the edges, and its surface as well as the edges are covered with fuliginous crusts. Usually the thirst is excessive, unquenchable ; the respiration more or less labored ; the alteration of the features indicates a profound prostration. As to the pulse, sometimes rapid and feeble, at other times it contrasts by its almost normal rhythm with the other symptoms. The mind is assailed by hallu- cinations whose rapid succession causes an incessant change. The words crowd each other so in the patient's mouth, that several demand utterance sim.ultaneously and escape with difficulty in jerky, interrupted, often unintellibible sen- tences. In constant agitation (jactitation), the head and hands are moved abruptly in all directions whejice the imaginary impressions seem to arise." Magnan's form differs but little. Its principal distinctive feature is the rise of temperature which is apt to run high and reach 40° C. {104'' F.), or even 42° C. (107.6° F.). This lasts without remission for two or three days or perhaps longer, and if not followed, as is usual, by a fatal result, gradually descends to the normal limit. This form also is marked by the constant presence of muscular movements, subsultus tendinum, jerkings and contractions of the muscles all over the body, and by the extreme muscular weakness which eventually results from this incessant activity. Lentz considers that the only symptom by which this form can be differentiated from that of Delasiauve is the possibility of ALCOHOLIC DELIEIUM. 137 prolonged remissions in which the consciousness may for a time become quite clear. The presence of a high and continued fever during an attack of delirium tremens, is always a symptom of most serious import. It denotes either the presence of some severe and dangerous complication, as pneumonia or menin- gitis, or it implies, as is thought to be the case at times, by certain authorities, an affection of the cerebral heat-centers, and thereby a wide-spread and dangerous condition of the cerebrum. In ordinary cases of delirium tremens, there is no rise of temperature whatsoever. Nacke says : " In a series of examinations of a small number of cases (eleven), a slight feverishness could be deter- mined in one-third of them. The maximum was 38.8° C, loi^ F. Any temperature above this pointed to some inter- nal inflammation, more especially pneumonia. In our cases a slight fever appeared in the evening only, as a slight rise of the physiological evening exacerbation of the tempera- ture, never in the prodromal stage, commonly only on the first, rarely on the second day of the true delirium. Pulse and respiration were commonly only slightly increased in rate." The cause of the fever in febrile delirium tremens is still doubtful. Magnan gives the results of five autopsies in which little definite was found beyond the injection and oedema of the cerebral meninges and a similar condition of the meninges of the spinal cord with injection of the gray substance of the latter. He himself says, that besides the hyperaemia, which sometimes ends in hemorrhage and thus attests the very violent irritation of the nervous centers, we scarcely find at the autopsy anything except the more or less advanced alterations of ciironic alcoholism. That delirium tremens may be complicated by menin- gitis, is, of course, well-known, and many instances have been published, of which, however, I will only refer to the cases of Bonnemaison. 138 DISEASES OF INEBRIETY. Wliether such complication exists in any special case, can, of course, only be decided after a careful consideration of all the symptoms. Whether in the febrile cases ending in recovery, the fever is due to complications meningitic or otherwise, or whether it is simply due to the violence of the cerebral irritation and the affection of the cerebral heat-centers has not yet been proved. The evidence in favor of tlie latter condition is up to the present time wliolly negative. Con- sidering the existence of heat-centers, as shown by Dr. Ott and others, proved, since no other cause of the liigli tem- perature is apparent, and since cerebral irritation evidently exists, it is assumed that the fever is due to the irritation of these centers. It must be remembered, however, that this is only a theory with some plausibility in its favor. Nacke is in favor of this view. As in Magnan's cases the temperature cannot be simply dependent on increased muscular action " since now at the autopsy of such patients, beyond the more or less marked hyperaemia of the central nervous apparatus, and tlie clianges produced in the system by chronic alcoholism, notiiing was found which could explain the violent fever, we must in tliese cases regard tlie fever as directl}' dependent on the action of the lately intro- duced masses of alcohol upon the heat regulators." We, however, do not believe that this question can yet be decided without further evidence. Anotlier form of delirium tremens has been noticed as coming from traumatism. This nervous affection, characterized by muscular tremor and a peculiar restless delirium, not infrequently follows the receipt of injuries in those accustomed to alcoholic stimulation. Some writers describe, under the terms traumatic delir- ium and nervous delirium, a condition frequently very similar to delirium tremens, wliich is said to occur in patients free from the alcohol habit, and to depend upon ALCOHOLIC DELIRIUM. 139 nervous prostration, often associated with shock and hem- orrhage. It is possible that failure to investigate previous habits with judicial acumen has allowed to arise a confusion between delirium dependent simply upon traumatism and delirium induced by traumatism in alcohol drinkers. The muttering delirium and muscular twitching that supervene in asthenia, from surgical as from medical causes, and the noisy delirium after injury that is exhibited by quick, rapid, and full pulse, and by febrile reaction, are two very differ- ent conditions to which the name traumatic delirium might with propriety be applied. These forms of mental disturb- ance, in my opinion, better called asthenic and inflamma- tory delirium respectively, arise without reference to per- sonal habits. The group of symptoms which I propose describing as traumatic delirium tremens, however, is found especially, if not exclusively, indeed, in those whose nervous systems have undergone, prior to injury, the deterioration due to absorption of alcohol, I have not been convinced by my experience, nor by my reading, that such a concatenation of symptoms can occur after traumatism in the absolutely abstemious. The amount of drinking requisite to induce the predisposition vai'ies with the individual. The repeated ingestion of quite small quantities of alcohol may give rise to the delirious susceptibility. It is possible that a similar deterioration of constitution, and a consequent liability to trembling delirium, may be caused by the opium, chloral, and tobacco habits ; but it is difficult to differentiate these because of their frequent association with alcoholic excess. Traumatic delirium tremens may follow even slight in- juries, but compound fractures and burns seem to have a special tendency to develop this serious complication. Its occurrence should not be ascribed to the restraint imposed upon the patient's habits by the injury, but to a traumatic disturbance of a previously unstable nervous equilibrium. 14:0 DISEASES OF INEBEIETY. Medical authorities vary in tlieir appreciation of the causa- tive influence exerted by sudden deprivation of accustomed stimulants in exciting attacks of ordinary delirium tremens. It is probable, however, that in a vast majority of such cases tlie directly exciting causes are tlie deficient assimila- tion of food, the anxiety, and the nervous strain which go hand in hand with a period of debauch, and which persist after the ingestion of alcohol is stopped. Neither is the occurrence of the malady to be imputed to the directly poisonous effect of a large amount of consumed alcohol, since acute alcohol poisoning, in persons unaccustomed to the use of alcoiiol, gives rise to stupor and death, but not to delirium. Traumatic delirium tremens occurs because chronic changes in the nervous tissue or blood, or perhaps in both, have rendered the alcohol drinker susceptible to such an outbreak upon the application of any disturbing influence. The receipt of injury is a sufficient perturbing force, especi- ally if tlie patient be on the verge of an idiopathic attack. It has been thought that the use of beverages containing amylic alcohol (fusel oil) especially predisposes to delirium tremens. The alteration in nerve structure or blood, which is the essential pathological factor of delirium tremens, is unknown to us. At autopsies, an abnormal amount of serum is usually found in the substance, and within the ventricles of the brain ; meningeal congestion and hemorrhage are often seen ; the cells of the gray matter, the cerebral connective tissue, the lymph spaces and the vessels may show sclerotic or fatty changes ; and the liver, kidneys, and digestive tract may exiiibit the characteristic lesions found in chronic alcoholism ; but there is nothing to which we can point as the distinctive lesion of delirium tremens. The initiatory symptoms of traumatic delirium tremens are sleeplessness at night, and slight tremor, which is readily noticed by ordering the patient to hold out the hand with ALCOHOLIC DELIRIUM. 141 widely-separated fingers. Subsequently, restlessness, insom- nia, and tremor increase, and delirium is. shown. The delirium, wliicli is often first exhibited at night, is peculiar. Tlie patient sees numerous small animals or insects creeping over the bed and about liis person, or is pursued by some hideous spectre. Hence, he is constantly endeavoring to eject the vermin from his clothing, or trying to escape the persecutions of his tormentor. I have now under my care a patient with traumatic delirium tremens, after an open fracture of the leg, who imagines tliat ele- phants are moving over his bed and tramping on his legs. He may, in his efforts to get rid of these disgusting and dis- tressing annoyances, leave his bed and fall from a window or down a flight of steps. The mental condition is one of depression, trepidation, and great activity. He is exceed- ingly restless, and is constantly chattering in a low tone, but, thougli he may cry out because of fear, he shows little or no maniacal excitement. He is good-natured, not prone to violence, and can often be aroused, by emphatically spoken words, to an understanding of his surroundings: but he soon relapses into the previous incessant chattering and motion. Very often a single idea recurs again and again to his delirious fancy, and not infrequently the delirium has a comical or tragedo-comical aspect. The muscular tremor is not like the twitching of tendons seen in asthenic conditions, but resembles the sliakiness, from want of coor- dination, seen in cerebro-spinal sclerosis. Often there is hurry in movement, and the limbs or tongue will then be thrust forward with a jerk. The tremor of delirium tremens reminds me much of the movements that would be expected in an association of chorea with sclerosis of the nervous centres. During these symptoms, the patient is unable to sleep, is incessantly in motion, and has a bright eye with dilated pupils, and an unsteady, restless look. He exhibits a moist, flabby, tremulous tongue with a whitish fur, desires 142 DISEASES OP INEBRIETY. no food, has constipated bowels, and passes a scanty, high- colored urine. In idiopathic delirium tremens of moderate severity there is no great acceleration of tlie pulse, and the temperature does not rise much above ioo°, except during active muscular exertion. In tliose graver cases, vi'liich Magnan calls febrile delirium tremens, the bodily heat is apt to remain in the neigliborhood of i02"-i25°, though there is no inter-current affection to keep up the temper- ature, and the pulse rate is also increased. In traumatic delirium tremens the constitutional disturbance, due to the wound, affects the pulse and temperature. The patient will often remove the dressings from his wound, or subject the injured limb to violent motion without appearing to experience pain. Traumatic delirium tremens arises, as a rule, within two or three days after the receipt of injury, and lasts usually not more than five or six days. The illusions are apt to continue during the night, even after the patient has become convalescent and quite rational in the daytime. The peculiarity of the tremor and delirium renders the diagnosis easy. If my view of its causation be correct, the existence of the characteristic symptoms is evidence of previous liabits of stimulation ; but it is not always well to mention this suspicion, nor to call the disease delirium tremens, since the patient's friends may be unaware of the existence of such habits. Death may occur from exhaustion, coma, or some inter- current affection, and is sometimes inexplicably sudden. Tlie character of the traumatism may determine the mode of death. Pneumonia is frequently associated with idiopathic delirium tremens. It is often, in fact, the exciting cause of the delirious outbreak, and, of course, in traumatic cases greatly diminisiies the chances of recovery. When the tem- perature shows a tendency to remain high without a suffic- ient traumatic cause, and especially when the tremor affects all the muscles of the trunk, as well as those of the head and ALCOHOLIC DELIKIUM. 14:3 extremities, and is not arrested during sleep, the prognosis is bad. A history of previous attacks of the disease renders the outlook more grave. In considering treatment, it is important to bear in mind that delirium tremens is an asthenic condition. There is action, but it is the activity of weakness, not of power. Depressants are therefore injurious. Five or ten grains of calomel, or one or two seidlitz powders, may be administered in the beginning of the disease, or when its occurrence is feared, because of the anorexia and gastric derangement. Concentrated liquid food, bitter tonics, and capsicum add to the patient's strength, and tend to give tone to the im- paired digestive organs. Bathing and mild diuretics may be employed, in the endeavor to eliminate the alcohol that has entered the system. Ciiloral hydrate (gr. x-xx) with potassium bromide (gr. xxx-xl) should be given every two or three hours, as soon as sleeplessness and slight tremor are noticeable ; no visitors should be allowed in the room. If the development of the attack is not prevented, the same treatment is continued, but the doses may be increased. The object is to quiet the nervous system and induce sleep. In this endeavor an occasional dose of morphia (gr. 1-4 to 1-3,) may be combined with the chloral and potassium bro- mide. The excessive use of opiates is undesirable, for it is not narcotism that is desired, but sleep; cerebral conges- tion is induced by overdosing witli morphia. If fatty heart exists, opiates should be pushed, perhaps rather than the chloral and potassium bromide. Tiie com- bination treatment with the three hypnotics allows the sur- geon to diminish or increase each element according to indications. Tincture of digitalis (m. x-xxx) every two or three hours, is valuable in cases of weak but not fatly heart, where there is pallor and cyanosis with probable anaemia of the brain. Strychnia also has been recom- mended in delirium tremens. Meclianical restraint, with the straps and the straight jacket, is only to be adopted 144 DISEASES OF INEBRIETY. when efficient watching and soothing by attendants is impracticable. All such apparatus excites the patient and is very liable to interfere with respiration. The best appli- ance is a loose but strong garment, consisting of trowsers and shirt, in one piece, with loops attached for fastening the patient in bed. Fractures should be dressed with plaster of Paris bandages, because ordinary splints will probably be displaced by the patient. If failure of vital powers is to be feared, alcoholic stimulants in small amounts, administered only when food is given, are judicious, because in chronic drinkers digestion will sometimes not go on sufficiently without the aid of alcohol. Such failure of assimilation in delirium tremens may turn the scale against the patient. Whiskey or brandy (F. i§-F. iv§ during the twenty-four hours) in the form of milk punch or egg-nog, is probably the best form of administration. Many pStients will not require any stimulants. Vomiting occurring in delirium tremens, is to be treated by milk and lime-water, cracked ice, effervescing drinks, bismuth sub-nitrate, pep- ain and carbolic acid mixtures. CHAPTER XVI. GENERAL FACTS OF HEREDITY AND PREDISPOSING CON- DITIONS. Alcoholic Heredity, or the transmission of a special ten- dency to use spirits, or any narcotic, to excess, is much more common than is supposed. In the study of a large number of cases, several distinct groups will be apparent. First will appear the direct heredities. Those inebri- ates whose parents and grandparents used spirits to excess. The line of tiie inheritance will be from father to daughter, and motlier to son ; that is, if tlie father is a drinking man, the daughter will inherit his disease more frequently than the son. While the daughter may not, from absence of some special exciting causes, be an inebriate, her sons will in a large proportion of cases fall from the most insignificant exciting causes. About one in every three cases can be traced to inebriate ancestors. Quite a large proportion of these parents are moderate or only occasional excessive users of spirits. If the father is a moderate drinker, and the mother a nervous, consumptive woman, or one with a weak, nervous organization, inebriety very often follows in the children. If both parents use wine or beer on the table continuously, temperate, sober children will be the excep- tion to the rule. If the motiier uses various forms of alco- holic drinks, as medicines, or narcotic drugs for real or imaginary purposes, the inebriety of the children is very common. Many cases have been noted of mothers using wine, beer, or some form of alcoholic drinks, for lung 146 DISEASES OF INEBRIETY. trouble or other affections, and the children born during this period have been inebriates, while others born before and after this drink period have been temperate. The second group of these alcoholic heredities are called the indirect. They are cases wljere the inebriety of some ancestor has left a stream of diseases, such as minor forms of insanity, consumption, and various nerve defects, whicii may have run through one or two generations, tlien suddenly develop into inebriety, with or without any special exciting cause. In such cases the moderate or excessive drinking parents will be followed by nervous feeble-minded, consump- tive, or very precocious children, or eccentric and odd people who are born extremists in every relation of life. They are persons who die early, and leave a large progeny, who suffer from nerve and nutrient troubles, and neuralgia, and find in alcohol and opium a most seductive relief from all their troubles. About one-fourth of all cases of inebriety are examples of this form of indirect heredity. A third group of heredities in these cases of inebriety, are the complex border-land cases. They are persons whose ancestors have been insane, epileptic, consumptives, criminals, pau- pers, and had other forms of degeneration. Victims driven along by a tide of degenerate heredity, which burst out in varied forms and phases of diseases. This class are seen among the very wealthy and the very poor. Fully one- fourth of all inebriates are of this class, and their inebriety is only another stage of profound degeneration in the march to dissolution. In these cases there seems to be in certain families a regular cycle of degenerative diseases. Thus in one generation great eccentricity, genius, and a high order of emotional development. Extreme religious zeal, or un- reasonable skepticism, pioneers or martyrs for an idea, and extremists in all matters. In the next generation, insanity, inebriety, feeble-minded, or idiots. In the third generation, paupers, criminals, tramps, epileptics, idiots, insanity, con- sumption, and inebriety. In the fourth generation, they die GENERAL FACTS OF HEREDITY. 147 out, or may swing back to great genius, pioneers, and heroes, or leaders of extreme movements. In the study of a large number of cases of inebriates, a physical and mental heredity will appear. Thus the children of inebriates for one or two generations will be found to have, as a rule, physical defects and deformities. Bad shaped heads and bodies, an inharmonious development, retarded or excessive growths, club feet, cleft palate, defec- tive eyesight, great grossness of organization, or extreme frailty of development. This can be seen in the observation of almost anyone, and indicates the defective nutrition and cell growth caused by injuries from alcohol transmitted to the children. The mental heredity from inebriate parents is equally clear and apparent to any close observation. Mental instability, and mental feebleness are common signs. Impulsive, excitable, emotional persons, who are on the two extremes, either buoyed with great faith and hope, or depressed to the verge of despair. Extravagant self-esteem, boundless faith in the most absurd schemes of politics, religion, and science. Men and women who are called " border-liners," mean- ing those whose good judgment and reason alternate back and forth over the line where sanity and insanity join. They are found in the great army of the irregulars, the intellectual and moral quacks, the badly-balanced, and weak, unstable mentality. Genius and precocity often appear in these persons. They frequently come into prominence like blazing comets, dazzling for a time, then disappear in some cloud of insanity, inebriety, or other disease. This mental heredity will be often seen in the per- verted nutrient tastes of children, the impulsive appetites, and dominant animal desires. With the very wealthy and very poor, these signs of alcoholic heritage are prominent. One of the reasons is the excessive nutrient stimulation from excess of quality and quantity of food, among the 148 DISEASES OF INEBRIETY. wealthy, and the opposite among the poor ; also the under- work and overwork of those classes. These are only hints and intimations along the shore of a great continent of facts, which some future explorer will reveal. It will be of interest to point out some of the results which follow from alcoholic heredity. First, the longevity is di?ninished. It is impossible for a generation with' this entailment to have the same vigor to resist disease and death. Exhaustive physical and intellectual exertion is not repaired and overcome so readily, and death from slight causes are more common. Thus exposure merges into pneumonia, and other fatal conditions, more quickly than in others without this entailment. In epidemics of fevers and other diseases these children of alcoholic parents, and inebriates themselves, die first. The}^ die from injury, shock, strain, worry, and care. In brief, this alcoholic legacy from ancestors means a short- ened life, an early death, from varied insignificant causes and general incapacity to bear the strains and drains of the ordinary activities of life. Second, by a wise limita- tion of nature the race with this heritage must die out. Only by a prudent ingrafting and marriage with a healthier stock can it be continued into the future. A family with this heritage is on the road to extinction, it is switched on a side track, and is moving on a down-grade of rap- idly increasing degeneration. Nature seems to often make an effort to put on the brakes and check the speed in some remarkable fecundity. Thus in these degenerate families you will often see a great number of children who, as a rule, exhibit many of the defects of the parents, and are short lived. The large families of children in inebriate parents may be taken as a hint of the approach of extinction for that race. In the same way, great genius in certain directions, as for instance a poet, an orator, an inventor, or a reformer, starting far away above the levels of his ancestors and sur- GENERAL FACTS OF HEREDITY. 149 roundings, are often the last members of families far down towards tlie rapids that precede the final plunge into obliv- ion, like the flicker of a lamp bursting into full blaze before extinction. Third^ where this alcoholic heredity is re- tarded or accelerated by the union with different currents of heredity, very strange compounds are the result. Thus, if to this alcoholic heredity are united a heritage of insanity idiocy, or any other pronounced defective influence, all grades of criminals, paupers, and mixed insanities follow. While most of these defects are apparent to ordinary obser- vation, yet there is a class of defectives springing from tliis soil which may be termed moral paralytics, which will be the subject of bitter controversy in psychological circles in the near future. Along this frontier line the great questions of free will and moral responsibility must be settled. The injury from alcohol first numbs, then finally paralyzes the higher brain forces, which includes all the moral elements. This paralysis goes down into the next generation as a con- genital deformity, a retarded growth, in the same way tliiit in some families cross-eyes, hare-lip, defective hands or legs, are seen in every generation. This form of heredity produces criminals of tlie most dangerous type ; men and women born without any consciousness of duty, of right and wrong, of obligation to live a moral, consistent life. From these mixed heredities some central brain region has become malformed and degenerate, and tlie victim is with- out power to change or comprehend the normal relations of mental or moral life. Many of these persons occupy places of wealth and influence in societ\\ holding positions of honor and respect, by force of surroundings and absence of opportunity to reveal their incapacity to follow lives of truth and justice. . . . If this subject is seen liigher up, other and more start- ling conclusions appear. First, this heredity from alco- hol is intensijied and increased by the misapplication of the educational forces of to-day. The highest culture of the best 150 DISEASES OF INEBKIETT. colleges, applied without regard to the natural capacity of the individual, and along unphysioiogical lines, must clear- ly unfits and destroys him. Often this higiier culture is abnormal stimulation and growth, particularly for the entailments of past generations. First of all, the educational systems do not alwciys build up healthy brain and nerve force. Seco?id, they ignore all heredity, and influences of food, climate, surround- ings, and natural capacity and the result is that abnor- mal impulses are intensified in certain directions, and the power of control is diminished in a positive substratum of exhaustion from which chere is no relief. The highest modern culture applied indiscriminately to children of inebriates, will result in tlieir ruin as positively as any degree of ignorance. This is seen in the inordinate self- esteem, feeble common sense, unstable will power, extrava- gant idealities, and general mental dyspepsia of many col- lege graduates. In actual life the college graduate who has an alcoholic heredity, and is an inebriate, is more incur- able than his brother who has never had a college culture. It has been truly said that ignorance will give more promise of longevity, and a final triumph over this heredity than the highest indiscriminate culture of to-day. Another view reveals the fact that the present legal methods to restrain inebriety, and the result of alcoholic heredity, pro- duce results exactly opposite. Thus the army of inebriates and irregulars of this family group are held accountable as healthy, responsible beings, and confined in most dangerous mental and physical surroundings, actually intensifying their defects and removing them farther from all hope of recovery. The police courts and jails are to inebriates literal training stations, for mustering in armies that never desert or leave the ranks until crushed out forever. A Chinese law, enacted a thousand years ago, and in force to-day, contains a flash of truth. When a criminal comes before the courts, careful inquiry is made into his ancestry. GENERAL FACTS OF HEREDITY. 151 If they are found to have any of the traits common to the prisoner he is killed and they are punished. His death ends all possibility of transmitted crime, and their punishment and recorded history puts a clieck on any farther propaga- tion of the evil. Common law and public opinion are far behind the march of science in a practical knowledge of this evil and the means to correct it. Not far away in the future this terrible shadow will vanish before a larger, clearer intel- ligence, and all our blind efforts of to-day will be found to be but a repetition of history — the stage of empiricism, quackery, and superstition, which precedes every great advance of humanity. From a highet' ;point of view, civiliza- tion and the increasing complexities and changing conditions increase this heritage. Thus every new^ invention which changes the direction of human activities, brings greater strain on the brain and nerve force, demanding new ener- gies, which the alcoholic heredity victim cannot give. He is unfitted and crippled for these new conditions of life by his forefathers, left dismantled and without strength for the race, and by that great law of our being is crushed out, driven out, and crowded out in the struggle and survival of the fittest. One great fact comes out prominently in this outline re- view, namely, that alcoholic heredity or a predisposition to inebriety, and many other nerve and brain degenerations, will certainly follow in the next generation from the moder- ate or excessive use of spirits. Parents who do not recog- nize this fact, practicall}', are committing unpardonable sins, by crippling the coming generations and switching them on the side-tracks, away from the main line of devel- opment. Another fact appears : education and marriage should be governed by a knowledge of heredity. Education should be detemined by the family physician, aud have for its ob- ject to control and antagonize all the predisposition of he- redity. Marriage sliould be under control of law, and from 152 DISEASES OP INEBRIETY. the judgment of the family pliysician. The time is coming when every family will have its scientific medical advisers, and these vital questions of heredity and practical life will be determined from a scientific basis. Still another fact comes up prominently. The great armies of the insane, inebriates, criminals, and paupers are largely the doomed victims of the sins of our forefathers. Our duty to them is to house them, to protect them from perpetuating their defects and injuring others. Science tells us that this army of hereditary defectives are wards of the State, and should be housed, quarantined, made self-supporting, and forced into conditions of healthy living. The present indis- criminate freedom of this class is a sad reflection on the intelligence of this century. The study of alcohol heredity furnislies not only the strongest reasons for total abstinence in each person, but reveals the laws and forces which gov- ern its march in each individual, revealing a wider range of the subject. Along this line of heredity will be found the practical solution of many of the mysteries and remedie-s of this great drink problem. In regard to the transmissibility of inebriety from parents to offspring through different branches and gener- ations, and its correlation with insanity, epilepsy, and other nervous diseases, there is far less known, in spite of all that has been written on the subject, than is needed to be known. It is not the disease, it is the tendency to the dis- ease that is inherited ; and this tendency is not transmitted to all the children, but is liable to be transmitted to some of them, and one form of nervous disease, as inebriety, in one or both parents, may, in some of the cliildren or more remote descendants, re-appear as epilepsy or insanity, or hypochondriasis. There is a general tendency to disease of the nervous system developed and fostered under our modern civilization and institutions, which I call the nervous diathesis, and which subdivides itself into various phases of nervous disease, such as neuralgia, sick headache, spinal GENERAL FACTS OF HEREDITY. 153 and cerebral irritation, hysteria, and hypochondriasis, as the hand brandies out into a tiiumb and fingers. A pliilosophic study of the transmissibility of inebriety requires tliat these otlier and allied disorders be studied in connection with it, and studied in this way it would be proved that in nearly all cases of inebriety, as in nearly all cases of other and allied forms of nervous disease, there was an inheritance of the nervous diathesis on one or on both sides, and usually also an inheritance, through near and remote relatives of some one of the various forms of nervous disease that spring out of the nervous diathesis. A similarly thorough investigation of nervous diseases of an allied character would show if not as marked, yet a very decided hereditary tendency in them all, and a con- stant tendency likewise to interchange, reversion, and cor- relation of the different manifestations of the nervous diathesis. Thus hay fever in a parent may appear as sick headache in one child, as epilepsy in another, as insanity in another ; in a grandchild as inebriety, in a nephew or niece as simple nervous exhaustion. CHAPTER XVII. FURTHER CONSIDERATIONS OF HEREDITY. Alcohol does not alone affect those who abuse it, but afflicts more or less grave disorders upon their children. Many books have been written on this topic, but heredity in nervous diseases resembles so closely the symptoms of alcoholic heredity, that the latter cannot always be distin- guished. Another cause of obscurity is owing to tiie fact that alcoholic excess does not necessarily come from alco- holism, and that alcoholism can exist apart from alcoholic excess. Alcoholism by itself in the ancestors does not neces- sarily predicate heredity in the descendants. This requires a whole group of symptoms. Many families in which excess have happened escape alcoholism, for the reason that a sufficient number of predispositions did not exist to take on a morbid form. Historically, alcoholic heredity was known since the days of mythology. We are told that Vulcan lame was conceived by Jupiter drunk. Diogenes, addressing a stupid child, said : "Thy father was drunk when thy mother con- ceived thee." Aristotle declared " that a drunken motlier would produce drunken offspring." The legislation of Ly- curgus promoted drunkenness in vanquished nations, that it might extinguish patriotism. The Carthagenian law prohibited any drink but water on the day of cohabitation with one's wife. Numerous ancient and modern authorities have repeatedly called atten- tion to the serious and varied effects of parental drunken- 156 DISEASES OF INEBRIETY. ness in the offspring. The first serious study was by the celebrated alienist Morel. He first defined the foundations of alcoholic heredity. His successors have done no more than develop what he had discovered. There are admitted to be two general forms : First, the homologous hereditary, or that of similitude. Second, heredity of transformation, or eccentric heredity. In the first form the progenitor gives to the descendant his ten- den, y to alcohol, or symptoms of his alcoholism. In the second form the alcoholized mental state of the progenitor becomes transformed into the varied nervous disorders of wiiich the body may develop. No alienist of to-day denies this direct heredity. The examples are too frequent and striking; but it must be remembered that heredity will appear under the most varied forms. There is but little agreement among authors about the frequency of its trans- mission. Dr. Dodge claims that fifty per cent, of all inebri- ates were hereditary. Dr. Bare believes that twenty-five per cent, are inherited. Dr. Kerr thinks over fifty percent. Dr. Magnan claims eighty per cent. Dr. Parrish eighty per cent. Dr. Crothers eighty per cent. Dr. Day seventy per cent. Dr. Mason sixty per cent. The mere appetite for drink transmitted from the par- ent to child presents so many varied aspects that it is diffi- cult to define any exact law for its manifestation. It is not rare to see it reproduced in the child with the same charac- teristics as exhibited in the parents. As a general law, it may be stated that hereditary alcoholism begins early, aug- menting, reaching its climax, and showing its greatest activity at manhood and at the menopause. Notwithstand- ing what we have said, heredity does not always reveal itself by this disordered appetite for drink. Heredity not unfrequently shows itself by irritability instability, and a vicious moral disposition, which seems to place the sufferer under some burden to find an excitement which will relieve him from his suffering. The laws of FUETHEK CONSIDERATIONS OF HEREDITY. 157 nerve and psycliopathic heredity govern heredity drunken- ness. For this reason it may be mediate or immediate, coming direct from parents or skipping several generations in their descent. Apart from the question whetlier strong drink produces alcoholism or alciiolism produces a desire for strong drink, it is certain that a variety of mental and nervous disorders engenders a desire for strong drink. Unfortunately the control of these cases is wholly unknown to us. Tiiis con- stitutes the first variety of heredity of similitude, which is the simple transmission of the defect from parent to child. A second variety of the same form is more discussed. This exhibits in the descendant symptoms of chronic alcoholism witliout any accompanying alcoholic excess. It is well ascertained that the drinker does not transmit the vice of drinking, but tlie disease of alcoholism. Sensibility is di- minislied in their descendants, and they have varied and complex symptoms of complex nervous disorder. The author cites two cases of the homiietic type, in which various nervous symptoms were present, but does not deem them marked typical cases. The heterotype form is more easily defined. Numerous observations render it cer- tain that epilepsy occurs under a reflex excitability produced by alcoholic heredity. The same mother with a sober man gives birth to healtliy children, and with a drunken man to epileptic cliildren. Statistics prove tlie presence of epilepsy in the children of drinking parents. Of eighty-tliree epilep- tics, sixty have been traced to drinking parents. Youthful convulsions are not less infrequent than epilepsy. In the families of sixty alcoholics, there were one hnndred and sixty-nine survivors, forty-eight of which experienced con- vulsions in childhood. In the case of twenty-three non-al- coholic families, having seventy-nine survivors, only ten had convulsions in youth. Another form of the heterotype order is seen in the hys- teria and sensitive states of women. In men, under the 158 DISEASES OF INEBRIETY. name of nervosisme, it offers an infinite variety of symptoms. A certain number of tliese nervous symptoms leave no doubt of their alcoliolic origin. The digestive function is especially the seat of these disorders, prominent of wliicli is nervous dyspepsia, vomiting, hyperaesthesia, insomnia, dreams, enfeebled muscular force, capricious character, and so on. The following clinical observations make this class more clear : A laborer, witii alcoholic father, mother, and sister, died of lung disease. He had convulsions in youth, is neu- ralgic, has headaches, stomach troubles, and is weakly. His character is unrestrained, imperious, and he has fears of becoming insane. He drinks but little wine, because it dis- agrees with him. B, a woman with an alcoholic father. She has vomitings every few days, although her menses are regular. For several years tliis dyspepsia is more pro- nounced at the menstrual period. Goes often without eat- ing, and has cramps of the stomach. Laughs and cries, and is very emotional at times. Has a nervous laugh, and neuralgia and analgesia all over the body. Sensibility to heat and cold is gone, and the sense of taste and smell greatly diminished. These cases give only some symptoms of the varied nerve troubles which follow from an alcoholic origin. Tliese states represent a continual progression from a simple neuro- pathic temperament to the most pronounced nervosisme. With women this nervosity is revealed by more or less pro- nounced symptoms of hysteria, unaccompanied by convul- sive attacks. A third manifestation of alcoholic heredity is impulsive madness, more rare than others. These are not explained apart from hereditary taint. Often it is the expression of an extended neuro-psychopathic condition. The moral perversions and atrocious crimes often seen can only be accounted for by the alcoliolic inheritance. In addition to this and opposed to it is another form of mania, consisting of a delirious obsession, which completely con- FURTHER CONSIDERATIONS OF HEREDITY. 159 trols the idea of the person, despite all his efforts to prevent it. Its approach is known to the sufferer, but he cannot deliver himself from it. It has only recently been described, and should be considered a consequence of alcoholic ances- try. Krafft-Ebing describes two cases of this kind, both of which had alcoholized fathers. One of these cases was a work-woman. She was hysterical from youth ; once had slight loss of consciousness ; the obsession approached gradually and consisted of melancholy and religious terror, with perplexities about dogmas. These culminated in a conviction to abstain from all food and drink. From simple mental weakness to absolute idiocy there are grades of degeneration which can be ascribed to hereditary alcoholism. These affections may be congenital and primitive, or con- secutive, in the sense that the slightest cerebral derange- ment will result in irreparable mental weakness. Lunier thinks fifty per cent, of tiiose who exhibit moral imper- fections are traceable to alcoholic forefathers. Beyond the definite cerebral and psychical derangements which we are acquainted with, there are many moral and intellectual perversions which alcoholic ancestry fully explains. These persons are the prey of moral degeneration inherited direct from their parents. From youth they exhibit the worst instincts, are cruel, vindictive, and quarrelsome. Their delights are in witnessing suffering and tormenting others. Later they are lazy, undisciplined, and vagabonds. Usually it is impossible or very difficult to educate tliem, and the period of puberty is the sign for throwing off all restraint. Idleness, indecision, vagabondage, moral perversion, rest- lessness, drink, and venereal impulses are their principal characteristics. These persons exhibit a wonderful precocity in develop- ing the drink habit, resulting in alcoholism more danger- ous from the fact of previous disposition to degeneration. They end by falling into the instinctive moral manias, the 160 DISEASES OF INEBRIETY. existence among criminals, which has been so much dis- cussed. These subjects usually pass through many jails and prisons before ending in asylums. Alcohol is even worse in its inflictions on the physical nature than on the moral. Children of alcoholized parents are nearly always timid, feeble, pale, bad nutrition, and lessened vitality, making them an easy prey to attacks of sickness. The muscular sytem is but little developed, and they suffer from general imperfect growth in all directions. One of the consequences of alcoholic heredity is the partial and unequal development of the brain, amounting to gen- eral or partial atrophy, unilateral, and accompanied by cranial malformations. With the microcephalus the organic development is incomplete, the cranium and superior region of the head is asymetrical, the body hemiatrophical. Another consequence of alcoholic degeneration is hydro- cephalic, and also infantile paralysis. In another order of observation it is found that alcohol heredity diminishes fecundity and birth. Lippich has demonstrated that alco- holized marriages produce two-tliirds less children than among those who were temperate. There can be no doubt that alcoholism affects the generative function of both sexes. The testicles undergo degeneration in alcoholized persons. The spermatic fluid shows this in the well-marked changes it exhibits, robbing it of the vitality indispensable to con- ception. The alcoholic cachexia, after it has attained suffi- cient intensity, will produce this, although the organs may not be themselves diseased. Many examples of women are noted who have had chil- dren by their first marriage, whose subsequent union was barren with an alcoholized husband, and also the reverse. Women may become sterile by alterations of the ovaries and matrix, and abort before maturity. From this point of view alcoholism in the mother is a more serious trouble than in the father. CHAPTER XVIII. STATISTICS OF HEREDITY AND OTHER CONSIDERATIONS. Dr. Matthews gives the following statistics of heredity : " The passion for alcoholic stimulants, if not reproduced in the immediate descendants, may show itself in the suc- cessive generations, and in all cases is the most prominent factor in insanity, epilepsy, idiocy, hypochondria, hysteria, neuralgia, nervous degeneration, and its kindred ailments — often manifesting these maladies in a vicious circle — with the effect of exhibiting insanity in one, epilepsy in another, intemperance in a third, idiocy in a fourth, hypoq^iondria in a fifth, hysteria in a sixth, and so on until the circle is completed, each generation increasing in numbers, and contributing in a direct ratio to the filling of our jails, pen- itentiaries, inebriate asylums, insane retreats and poor- houses. That this is not a conjectural statement the fol- lowing facts will abundantly prove : In a Swedish asylum it was found that 50 per cent, of the patients had been addicted to the use of alcoholic beverages. After the removal of the heavy tax on alcoholic drinks in Norway, the percentage of increase during eleven years was : In mania, 41 per cent. ; melancholia, 69 per cent. ; dementia, 25 per cent. ; and idiocy, 150 per cent. Of the last, 60 per cent, were the children of drunken fathers and mothers. In the insane hospital at Vienna, Austria, probably one of the largest in the world, the superintendent informed me, personally, that from 50 to 60 per cent, of the insanity was due to spirituous liquors. This percentage in a country 161 162 DISEASES OF INEBRIETY. where it is claimed alcoholic drinks do no harm, is well worth noticing. In our own State insane asylum, of the now present in- mates, numbering 364, 75 per cent, can be ascribed to habits of intoxication, either on their part or that of their ancestors. 1 am also authorized in making the statement that fully two-thirds of those persons requiring aid from city and Slate are descendants of inebriate parents. In one of our promi- nent lunatic asylums 637 cases were traced to intemperance as the assignable cause of their insanity. The statistical accounts of the State of New York give the following facts : In the poor-house of Ontario county there were 113 inmates. These, together witli their ancestors for three generations, living and dead, represented 90 families, and in these fam- ilies there were 168 dependents, 26 insane, 12 idiots, 103 inebriates. In Columbia county, 118 inmates, representing 114 families, had 143 dependents, 12 insane, 32 idiots, 127 inebriates. In Yates county, 32 inmates represented 26 families, of whom 59 had been dependent, 4 insane, 2 idiots, and 31 inebriates. In Kings county, 1,876 inmates repre- sented 1,668 families, 2,039 dependent, 755 insane, i-3 idiots, and 973 inebriates. Herkimer county had 77 inmates, rep- resenting 67 families, 128 dependents, 21 insane, 12 idiots, and 64 inebriates. The total in the alm.s-houses of the State was 12,614 inmates, who represented 10,161 families, whose members for three generations, living and dead, had among them 14,901 dependents, 4,968 insane, 844 idiots, and 8,863 inebriates. In round numbers, here are 10,000 families who have produced 15,000 paupers, or 3 paupers for every 2 families — of insane, about i for every 2 families ; of insane, inebriates, and idiots combined, about 15,000 or 3 to every 2 families." Dr. Wright asks : Is there a form of inebriety allied to those neuroses which mark a constitutional defect in nerve balance, a defect, the conditions of which are transmissible by heredity ? Some noted gentlemen deny the reality of STATISTICS OF HEREDITY. 163 the dipsomanical diathesis, and especially deny that such a constitutional proclivity can be handed down from ancestry. The real importance of the subject causes one to inquire with a good deal of interest: "What do the highest authorities say on these points ? The testimony of such eminent physicians as Hughes, Parrish, Crothers, Mann, Mason, and others in this country ; and Clouston, Mitchell, Kerr, Peddie, Cameron, Carpenter, and a host of others in Great Britain, any one of whom is fully competent to decide on the merits of the question, and who have con- scientiously studied inebriety for some years, will not be taken. Their great interest in the subject might expose them to the imputation of prejudice in viewing the facts. Authorities who are supposed to contemplate scientific principles through an atmosphere pure and uncolored by sympathy, are the only ones who will be questioned. The attempt will be made to show that if epilepsy, spasmodic asthma, prolonged neuralgia, hysteria, suicidal melancholia and the like, are constitutional diseases, then dipsomania, or as it is called by some, inebriety, is also a constitutional disease. Morel, when speaking of the degeneration and final extinction of a neurotic family strain, gives a history from his own personal observation thus : " First generation — immorality, depravity, alcoholic excess, and great moral degradation in great-grandfather who was killed in a tavern brawl. Second generation — hereditary drunkenness, mania- cal attacks ending in general paralysis in grandfather. Third generation — Sobriety, delusions of persecution, and homicidal tendencies in father. Fourth generation — defective intelligence, mania at sixteen ; transition to idiocy ; gener- ative functions feeble ; sisters imbecile ; wife had a bastard child of good constitution." When treating of heredity, Maudsley divides the subject into three branches : ist, heredity of the same form ; 2d, of allied form ; 3d, with transformation of neurosis, as when the ancestral defect was 164 DISEASES OF INEBRIETY. simply a nervous disease. Of heredity of tlie same form, this author says : " That is, when a person suffers from the same kind of mental derangement as a parent, whicli he sel- dom does, except in cases of suicide or dipsomania."' Dr. M. says in another place : " This mingling and transformation of neurosis which is observed sometimes in the individual, is more plainly manifest when the history of the course of nervous disease is traced through generations." The book of inebriety is open everywhere and to everybod}'. But to study its pages aright, particularly in respect to its habits of descent through individuals and generations, the observer himself must abide for a long series of years amongst one and the same community of people. It is obvious that in this way only can he study the facts respecting the influence of alcohol upon individuals and upon families. In the work already cited it is written : "With respect to an individual's legacy from his parents, he inherits not only their family nature . . . but something from their individual characters, as these have been modified by their sufferings and doings, their errors and achievements, their development or their degradation." Dr. Blandford {Insanity and its Treatjnenf, p. 139), speaks as follows : "As I have said, the particular cliaracter of the mania or melancholia depends on the constitution of the individual, , . . and the same person may at one time be maniacal and at another melancholic. It is true, we fre- quently see the same form in successive generations, e. g., suicidal melanchol}^ and hereditary drunkenness. He teaches that- there is a vast number of cases whei'e the descending form is different from its parent ; and that the same form may, or may not, appear in posterity. The idea that the hereditary transmission of different but inter- changeable neurotic form is an indication of the insane temperament is universal amongst alienists. Tliat "alco- holism is more liable to produce epilepsy, or idiocy, than to repeat itself," places alcoholism (or inebriety) at once STATISTICS OF HEREDITY. 165 amongst the hereditary and insane neuroses. " Hence, I believe springs the ever renewed insanity inebriety of our lower classes . , . My opinion is, that amongst the lower classes of our countrymen, insanity is on the increase. . . . There is a degree of drunkenness among the lower classes of this country that is not found in the higher. . . . The amount of drunkenness is enormous, and is almost confined to the lower orders — below the shopkeeper class." This is placing habitual drunkenness, or rather the neurotic mood which craves intoxication, very closely in alliance with those neurotic states which immediately inter- change with true insanity, it does indeed classify them together as one family. The intense desire for intoxication which is distinctive of the dipsomaniac, appears to issue from some unstable or abnormal state of the brain, as other lawless and unmanageable nervous symptoms frequently do, speaking of the influence of parentage in impressing a morbid diathesis upon posterity, uses this language : "The causes of insanity may come into operation at the period of conception. We should expect this a priori, and experience appears to prove it. We allude more especially to the case of a parent begetting children when drunk." " When mental disease is transmitted, does the form of insanity descend ? Very frequently this appears to be the case," says Dr. Tuke. The doctor then proceeds to give examples from various authorities of the direct descent, from ancestry to posterity, of hallucinations, monomania, melancholia, mania, general paralysis, and idiocy ; and then he adds upon his own authority : " Of dipsomania, the cases are so common that it is not necessary to detail any examples." Dr. Tuke gives a table " Exhibiting the proportion of hereditary cases /;/ the different forms of insanity, observed in the Cricliton Institution, as reported by Dr. Stewart." Mania descends as such in 51 per cent, of cases ; melaneholia, 57 per cent. ; monomania, 49 per cent. ; moral insanity, 50 per cent. ; idiocy and imbecility, 166 DISEASES OF INEBRIETY. 36 per cent. ; dipsomtuiia, 63 per cent. ; general paralysis, 47 per cent. ; dementia and fatuity, 39 per cent. Dr. Wynter says : "Among the more special forms of moral perversity, or as the alienist physician would say, insanity, which are transmitted by an insane parent, may be mentioned dipsomania." Again, tiie same author speaks of " the known fact that persistent drunkards plant the seeds of insanity and the other allied diseases in the offspring. Once planted there, the fruits may be diverse ; in one, there may be persistent neuralgia ; in another, the ancestral drunkenness may assume the form of dipsomania ; while another may be affiliated with partial paralysis or with epilepsy." Dr. Forbes Winslow declares : " I maintain, and facts clearly demonstrate my position, tiiat there is a vast amount of crime committed by persons who occupy a kind of neutral ground between positive mental derangement and mental sanity. I do not support the dangerous opinion that all crime is referable more or less to aber- ration of mind, but I do affirm that in estimating the ^w^i^/z/ of puJiishment to be awarded, it is the dut}'^ of the judge, not only to look at the act itself, but to consider the physical condition of the culprit, his education, moral advantages, prior social condition, his early training, the temptations to which he has been exposed, and, above all, whether he has not sprung from intemperate, insane, idiotic, and criminal parents." Dipsomania is declared by authorities to be one of the hereditary transmissible neuroses, wliich is interchangeable with other neuroses that are undisputably allied to insanity. Dipsomania is an aptitude for intoxication, but it is an apti- tude that is not subject to rules or laws. It is pathological for it is insatiable, unmanageable, in fact, an outlaw. Dr. Elam asserted : " The offspring of the confirmed drunkard will inherit either the original vice or some of its count- less protean transformations^ STATISTICS OF HEREDITY. 167 Dr. Anstie affirms : " In the course of a large experi- ence of alcoliolism among hospital out-patients, I have been greatly struck witli the number of drinkers who have informed me that their relatives eitlier on the paternal or maternal side have been given to drink ; my own experi- ence has led me to a firm conviction that particular causes of nervous degeneration affecting individuals, do very fre- quently lead to the transmission to the offspring of those persons of an enfeebled nervous organization which ren- ders them peculiarly liable to the severer neurosis and which also makes them facile victims of tlie temptations to seek oblivion for their mental and bodily pains in narcotic indulgence. I believe that things often work in a vicious circle to this end, and that the nervous enfeeblement pro- duced in an ancestor by great excesses in drink, is repro- duced in his various descendants with tlie effect of produc- ing insanity in one, epilepsy in another, neuralgia in a third, alcoholic excesses in a fourtli, and so on. Among the higher classes, where it is easier than in the case of the poor to obtain tolerably complete family histories extending over two or three generations, careful inquiry elicit facts of this kind with surprising frequency. So strong is the im- pression left on my mind by what I have observed in this direction, that I am inclined to believe that the great ma- jority of most inveterate and hopeless cases of alcoholic excesses among the higher classes are produced by two factors, of which the least important is the circumstance of external momentary temptation, in which the person has been placed where the more momentous and mighty canse is derived from an inherited nervous weakness, which renders all kinds of bodily and mental trouble specially hard to be borne. Dr. Wright says : " Observation teaches no lesson more clearly, unmistakably and universally, than tlie absolute certainty of heredity. Nothing escapes it — neither the slightest physical formation or movement, nor the faintest 168 DISEASES OF INEBRIETY. hint of a mental or moral impulse. Race propagation is simply the handing down of the salient features of one gen- eration to succeeding ones. There is no necessary progres- sion, deterioration, or change. But heredit}^, in its highest sense, is particularly concerned and exact in transmitting an immense number of personal cliaract^eristics derived from the innumerable associations, good, bad and indiflfer- ent, that have been connected viMth individual existence. " The main features of humanity are one and unvarying ; but the acquired " peculiarities " of families, and especially of individuals, are the reflections of the possibilities of human life. They measure the capabilities and the defects of man's nature, as they are susceptible of development by personal contact with the ever-changing situations, and the endless accidents of time. To the descent by heredity of the acquired characterics of individuals in varying forms, and by unnumbered vicarious substitutions, we owe the strength as well as the weakness of the race. The poten- tialities of humanity, exhibited in the beauty of one, the eloquence of another, the artistic genius of another, the fortitude and patriotism and unselfishness of others, illus- trate and also demonstrate the existence in the human race of qualities far greater and more glorious than the highest achievements of minds merely symmetrical can possibly evince. These potentialities are the outcome of personal traits formulated in individuals by contact with the experi- ences of life, and transmitted in endless variety of combina- tion and form by the power of heredity." Dr. Kerr : " This heredity may be regarded as two-fold. There is the direct alcoholic inheritance. That drunkards beget drunkards is an axiom dating from very early times. There are also large numbers of children born with an inherited and extremely delicate susceptibility to the narcotizing action of alcoholic intoxicants, whose parents were not in the habit of getting drunk, but drank regularly STATISTICS OF HEKEDITr. 169 and freely, physiologically intemperate, though considered by the world to be models of sobriety. " There is also the indirect inheritance of alcohol. Under this category are ranged individuals who have no special proclivity to excess, who have no direct though latent proneness to inebriety, but who are weighted from their birth by a controlling power too feeble to stay the advances of alcohol within their very being. Alcohol, if it gain an entrance into such constitutions by however tiny an inlet, slowly yet steadily widens the aperture by increasing in volume, as the dykes built to resist the encroaches of the ocean, till all the defenses are swept away by the over- powering and overwhelming flood. In no inconsiderable proportion of cases this defective power of control is the product of alcoholic indulgence on the part of one or both parents. " I have seen the alcoholic habit in the parent bear diverse fruit in the persons of the offspring, one sister being ner- vous, excitable, and inebriate, a second consumptive, a third insane ; one brother an epileptic and a periodic inebriate, the second in an asylum, the third a victim to chronic inebriety. In another instance, where all the four children have become habitual drunkards, the grandfather had also been addicted to excess. " The heredity is sometimes crossed. The daughters of a drinking father, and the sons of a drinking mother may be the only children affected with the inebriate taint, " The heredity may be either insane or inebriate. As inebriate parents not unseldom beget insane offspring, so from insane parentage we sometimes get inebriate children. The heredity may be of some other type. Any transmitted disease or effect of disease which increases nervous sus- ceptibility, unduly exhausts nerve strength, and weakens control, may bear a nervine crop, in the form of asthma in one child, hysteria in another, epilepsy in another, idiocy in another, and inebriety in another," 170 DISEASES OF INEBRIETY. Dr. Dacaiene concludes an exliaustive study as follows: " ist. Under tlie name liereditary alcoholism is included the totality of tlie pathological manifestations transmitted to a child by one or the other of his parents who are drink- ers, and sometimes both. " 2d. The inheritor of this taint, as well as the drinker himself, can hand down not only his own vice, but a special morbid tendency, a particular neuropathic state, which can always be charged to inebriety. "3d. The alcoholic inheritance may at first be dormant. When it exists it shows itself in infancy, or later, or in another generation. It shows itself as congenital paralysis, convulsions, epilepsy, hypochondriasis, idiocy, etc. * 4th. The increase in the number of the insane, of the number of suicides, of crimes and misdemeanors, such are the results of hereditary alcoholism. "5th. It is in hereditary alcoholism that can be found the explanation of certain monsters who come from time to time to horrify society and scandalize the courts of law. " 6th. These degenerate beings are smitten with sexual impotence. T!ie female inebriate is apt to abort, and lastly the mortality of the newly-born among drinkers reaches a figure truly frightful. " 7th. It has often been proved that in the case of drink- ers, there is a loss in stature and physical force. " 8th. To sum up hereditary alcoholism as well as the acquired, determines an enfeeblement of the species, the destruction of the family, and the degeneration and abase- ment of the race. "9th. From amedio-Iegal point of view, the hereditary inebriate, in particular the dypsomaniac, should be regard- ed most of the time as irresponsible, or at least his respon- sibility should be regarded as very limited. He is a sick man, who should be cared for, remembering that he presents an undeniable propensity to sickness, that he possesses a defective intellectual organization, in a word that he is a STATISTICS OF INEBEIETY. 171 degenerate. If the moral sense has not completely disap- peared in his case, at least its use is not accurately regula- ted. The judge then ought to take into account this moral state in appreciating Iiis acts. Dr. Lykke, Copenhagen, has shown clearly that heredity is a powerful factor in the origin of dipsomania. He indicated that psychical abnormities in the parents are developed in the next generation, and that if an improve- ment of the morbid condition is not attained by inter- marriage, the result will be complete degeneration. One of the prominent symptoms of such degeneration is a lack of moral capacity, and the preponderance of ungovernable instincts and dipsomaniac tendencies. Hence he supposes dipsomania to be a symptom of hereditary degeneration or insanity. Briihl Cramer, from a long examination of this subject, concludes that drunken parents are seldom prolific, and when so, the children are stupid, malicious, and full of mental defects. Skae and Thompson have both made deep researches into the hereditary disposition. The cases which they examined were largely of the mixed form of dipso- mania, and all sliowed decided tendencies to insanity. Skae found in eighty-two, thirty-two cases of inherited dipsomania. In the parents of the cliildren of the collateral branches, he found drunkenness, dipsomania, suicide, and other mental diseases. Thompson found in twenty cases, nineteen in which inebriety was clearly inherited. Many of these families containing two, four, and eight members, were all either drunken, epileptic or insane. In three families which I have studied, where both parents were drunken and insane, every single member following suf- fered from mental defects, of which epilepsy, dipsomania, and suicide were most common. All authors agree tiiat heredity is the prominent cause in the etiology of dipsomania ; but they disagree as to the place it should occupy in the nosology, and whether it 172 DISEASES OP INEBRIETY. should be considered as a principal disease or only as a symptom. It is clear that insanity and nervous diseases develop into dipsomania in the next generation, and vice- versa. The intimate relation between these diseases is evi- dent. CHAPTER XIX. GENERAL CONSIDERATIONS OF THE PATHOLOGY OF INEBRIETY. When a considerable portion of alcohol is consumed at one time by a person perfectly sober, certain characteristic appearances will usually be observed to follow immediately. There is a decided shock throughout the whole system. The face will often be very pale. This will be more notice- able in nervous and sensitive persons. The muscles of the face will be drawn, and fixed in position. The eyes will be bright and glittering, while their movements will be quick and constrained. The mouth will be firmly shut ; but when an effort is made to speak, the lips will be spasmodically affected. The breath will be short and panting, the pulse accelerated, and the articulation interrupted and difficult. The entire body will be affected by a trembling movement and a sensation of shivering. In fact, there will be a brief nervous chill. All these features appear at one and the same time. The period of their duration is very short, how- ever. After the lapse of five or ten minutes at most, the second stage, characteristic of heavy drinking, will come into view. Movements will appear unnatural, and very quickly will seem absolutely distorted and staggering. Intellectual activity, also, will speedily appear both irregular and unsteady. The voice very likely will be elevated, and an incessant chatter of speech, laden with absurd boasting, will din the ear. The brim of the hat will perhaps be 173 174 DISEASES OF INEBRIETY. thrown upward, or the hat itself placed upon the side of the head, or thrown backward, revealing the noble forehead. Indeed, the conditions are now all present for a full display of aggressive vulgarity and foolishness. The ruffianly instincts being aroused by alcohol, the garb of the ruffian is put on. For truly it is a fact, that when a man, being sober himself, arranges his attire like that of a rowdy, as thrusting his pantaloons inside his boot tops, turning upward the brim of his hat both in front and behind, and tying a handkerchief loosely about his neck — he will begin to feel like a rowdy, and to act like one. He will, perchance, stick his fists down deep into his pockets, while, possibly, he pours forth profanity and tobacco-juice in equal volumes. This description, of course, is not of universal applica- tion. In different persons there are considerable modifica- tions in these particulars, owing partly to peculiarities of individual constitutions, and partly to the kind of alcohol contained in the liquor that has been taken. But, let the constitutional disposition be what it may, the full drink of alcoholic liquor will induce displays in movement, mind, and morals, that are unwortiiy of the individual : and, the liquor being the same, these displays will, in a given indi- vidual, always be practically the same. Differences in the kind of alcohol will doubtless occasion considerable difference in the conduct of those who indulge in the alcoholic habit. Dr. Norman Kerr, in his very able work on Inebriety, says : "All alcohols are poisonous. The least poisonous are the alcohols of wine. More poison- ous are the alcohols of beet-root. Still more deadly are the alcohols of corn (all kinds of grain) ; and the most potent and pestiferous are the alcohols from potatoes. Cider inebriates are usually more heavy and stupid than alert and offensive. Amylic alcohol is nearly four times as poisonous as ethylic." Amylic alcohol quickly brings on muscular tremors and delirium tremens — whereas the PATHOLOGY OF INEBRIETY. 175 ethylic does not readily produce such effects, if it does at all. It is therefore perceived that while there is a sameness in the physiognomy of conduct under the influence of alco- hol, tliere is likewise a certain difference in details, in accordance with the particular kind of alcohol that is taken, A drunken man will not be of so unruly and satanic tem- per after partaking of wine, or of stronger drink derivetl from wine, as he will after partaking of beet or potato whiske}' ; and he will come out of his drunken state more quickly, and witli less distress in the former than in the latter contingency. There are many persons who drink alcoholic liquors with- out any driving impulse to intoxication. It is a common belief tiiat alcohol adds to the natural powers of the organ- ism ; and hence, alcohol is frequently taken in order that, tiirough an intensified capacity, ends may be secured that would otherwise be impossible. In this respect, the occa- sional drunkard is to be distinguished from the spasmodic or impulsive drunkard, whose whole aim is to secure intox- ication for its own sake, and also to secure it quickly and completely. Drinking fro7n association. — There are many persons who drink alcoholic liquors only as accidental contingencies and opportunities offer. They do not purposely seek the means of intoxication. The motives which actuate them in drink- ing are wholly derived from circumstances external to themselves and which are truly fortuitous. Yet the occa- ssional drinker cannot be said to be devoid of even strong motives for his indulgence. Sometimes a man will drink alcoholic liquor simply because he happens to be in com- pany with others who are drinking. The natural, but occa- sionally idle sympathy, which is so apt to bind men together in a common course of conduct, is sufficiently powerful to lead to a community of action, even in the matter of drink- ing liquors. Such cause for drinking may be operative on public days, or in companies that are engaged in enterprises 176 DISEASES OF INEBRIETY. wherein there is unity of feeling and purpose — and, of course, good fellowship — as, at log-rollings, barn-raisings, and the like. Drinking from this cause is not apt to lead to very seri- ous consequences. It is true, however, that if there is any considerable constitutional irritability of nerve in an indi- vidual, even an accidental indulgence may ignite a flame tliat can never be extinguished ; and in this way the occa- sional drinker ma}'^ become an habitual drunkard. The pleasurable sensations of early drunkenness are not so pronounced in the occasional drinker as they are apt to be in tlie spasmodic inebriate. This migiit be expected when it is remembered that an exquisite sense of mental and physical delight is one of the ruling inducements to frequent intoxication — that is, to intoxication for its own sake. In a stolid mind, rage and hate are not unlikely to be aroused by alcohol, instead of generosity and good temper. Misfortunes^ either domestic or in business, often lead to drinking. The benumbing influence of tlie alcoholic potion renders callous the distressed mind and quivering nerve. It is not always for excitement that alcohol is taken into the system. It is sometimes taken to secure repose ; and tliis repose is simply paralysis, more or less complete. In the paralysis of sensation, pain is abated ; in the paralysis of the co-ordinating nerve centers, moral and sympathetic afflictions no longer harass the mind. Alcohol is a com- plete remedy ; for the paralysis of alcohol extends through- out the whole body. It is seen in the motor system through the staggering gait, the imperfect articulations, the distorted countenance. It is perceived in the organs of sensation through the general numbness and the absence of the sense of feeling. The intellectual powers exhibit the paralyzing properties of alcohol, through confusion of mind, distortions in ideas, and in the irregular operations of the imagination. The same paralysis is seen in the PATHOLOGY OF INEBRIETY. 177 moral sense through the loss of that sense, and the inflow of untruthfulness, deceit, and prevarication. A deatli in the family is followed sometimes by deep potations on the part of the survivors, with the object of inducing a forgetfulness or partial unconsciousness of trouble. Yet the time thus consumed is expended in vain. It cannot serve to shorten the period which truly is requisite to assuage the intensity of sorrow. In truth, when this drunkenness has passed away, the poisoned nerves are in a pitiable state of excitement and tremor, much greater than oppressed them in the first place. With renewed distress and intensified grief, the mind is compelled to await all the longer for consolation and repose. It is in this condition of mind and nerve — after drinking is abated — when some- times suicide is invoked to vanquish once for all the com- bined horrors of grief and intemperance. Alcohol iniwked to increase the power of physical endurance. — ■ The casual drinker takes alcoholic liquors oftentimes with the view of increasing the powers of bodily endurance. The acuteness of the feelings being subdued by the nervous tor- por superinduced by alcohol, the sensations of cold and heat are not keenly presented to the mind. Yet this fact does not give the physical organism any immunity from the extreme effects of changes in the temperature. Experience has shown that persons exposed to cold, wet, and fatigue, sustain themselves much better without alcohol than with it. The truth is, that alcohol reduces the temperature of the human body, as the thermometer fully demonstrates. Therefore, the drunken man perishes from cold more readily than the sober man. For, not only does alcohol abstract oxygen, the source of heat, from the blood, and thus reduce the fires of ordinary physiological combustion, but it benumbs and paralyzes certain nerve centers, whose office it is to preside over the regulation of animal heat. As a remedy in violent fevers, alcohol is extensively used for reducing the dangerous heat of the blood. As a trickster 178 DISEASES OF INEBRIETY. and fraud, nothing can exceed alcohol, if indeed, it can be equaled. He who relies upon alcohol to warm him when cold is cheated and deceived. Alcohol as sustaining muscular efficiency. — Men frequently take ardent spirits with the notion that it will increase the bodily strength. The professional athlete, however, who understands the subject, will carefully avoid alcohol when upon the verge of action. There are several sound reasons for this, (a) The benumbing effect of alcohol upon the nervous powers is universal. It includes the muscular sys- tem in common with all others. The readiness of muscular contraction — its exact concord of action throughout the whole of its substance, and the completeness of its move- ment, all depend upon the natural strength, quickness, and sharpness of the nervous influence whicii is brought into play. But this influence is dwarfed and minimized by the paralyzing impression of alcohol, (b) The heart in intoxi- cation is thrown into increased action to the extent that the additional duties which very great muscular effort would impose upon it, are too great for its capacity, (c) The lungs refuse the breath requisite to extraordinary muscular effort when a man is drunk ; for in drunkenness they have a double duty to perform. They are busy, not only in exhaling the alcoholic poison, but also in disposing of the deleterious material ordinarily thrown out by them. Consequently, when uncommon muscular effort throws upon them an excessive volume of blood, they are unable properly to dispose of it. The man speedily gets out of breath, and is compelled to moderate his efforts. The base ball player is sadly deficient when under the influence of liquor. He cannot judge correctly with respect to distance, nor tell the true direction or velocity of a fly- ing ball. He can neither catch nor throw with his usual accuracv. His eyes are wanting in alertness of action, if not in correctness of vision. His movements and his judg- ment are equally at fault. The disabling powers of the PATHOLOGY OF INEBRIETY. 179 alcoholic potion are plainly displayed in the destruction of the normal relationship whicli should exist between the great divisions of human nature — mind and body. The perceptive faculties, as observed through the operations of common sensation and the sense of sight, are benumbed, while the muscular alacrity answering the calls of volition and judgment is absent. In brief, the atlilete has not vol- untary control of his muscular powers when under the dominion of alcohol, for paralysis, in whatever degree it exists, withdraws function in a corresponding degree from volition. Yet alcohol is wonderfully complicated as well as positive in its activities — volition itself being dull and paralyzed as well as the muscular system. Similar considerations are applicable to almost all ath- letic or muscular exercises. The swordsman and the pugilist must possess not only a steady but a correct nerve. It is indispensable to success that the eye and the hand be untrammeled and alert, but they should also be in exact harmony with each other in quickness of perception and movement. The details should be right, and the great movements of the system, which combine the details, should be unimpeded. The prize fighter knows the fact that the universal dullness of nerve wrought upon the organism by alcohol is fatal to his efforts for victory. It is amazing to see the absolute confidence with which a person under alcoholic influence views his powers, when the knowledge of the disabilities imposed by it are not recognized. In him, all the nagging asperities of nervous activity have dis- appeared. Nothing seems impossible to the transcendent egoism of a drunken man. The very suggestion of unfit- ness or mistake is scouted by him. Equally unable to fore- see, or appreciate difficulties, he has no faith in their existence. One A , a physician of ability, while considerably intoxicated, was handling a pistol, and accidentally dis- charged it. The ball flew near his wife's head, and shat- 180 DISEASES OF INEBRIETY. tered a looking-glass behind her. He was astonished exceedingly, and, with respect to this matter, he remains so to this day. His confidence in the absolute infallibility of his care and caution was simply impregnable — as it is, indeed, in every man who is drunk. Yet in this very thing he was terribly deceived and beguiled by alcohol. The sense of feeling in his hand was benumbed. He grasped the pistol with more force, and pressed upon the trigger more firmly, than he had any idea of, by reason of his impaired sense of feeling. The truth is, the confident approach of a drunken man is always amazing. His sense of feeling is dulled, and he seizes the person of another in a rude manner. His grasp is painful because it is vio- lent. The inebriate unconsciously exerts considerable force in his movements, in order to feel that he is really in con- tact with tilings or persons exterior to him. In the case of A , in whose liands the pistol was discharged, the har- mony of action between the eye and hand was deranged, through deadening of the nervous sensibility. The con- sequence was that, what he supposed was a normal com- munity of action between distant, but auxiliary parts, was an unnatural and inharmonious relationship. It was in obedience to that unrecognized condition, affecting alike mind and sensation, that the explosion took place, and not from a condition thoroughly regular and under the control of volition. How often has a drunken man had cause to bless his "good luck," when a gun went off without dealing death, while in his hands ; and how often again, has regret and remorse followed him through life, because some weapon has been accidentally fired by his awkward and trembling movements — maiming, or possibly killing some friend or companion. A young man, Samuel L , recently shot a female companion through the head, killing her instantly. They were both partially intoxicated. The pistol was of cheap PATHOLOGY OF INEBRIETY. 181 pattern, and was very unreliable about the trigger. The shooting was claimed to be an accident. The young man was no doubt in a state of more or less muscular incapacity. Testimony was given that in handling a pistol by a person drunk, it would more likely to be accidentally discharged than it would be in the hands of the same person when sober. Although in this case other facts pointed to mur- der, yet such a plea in defense might have been perfectly good and proper. A drunken man cannot dance. It does not require a very considerable degree of intoxication to disable a person for dancing. Anything which requires a community of action amongst a number of muscles — an3'tliing which is in the line of auxiliary aid, or help in muscular actions, is an utter impossibility for the individual who is intoxicated. Yet, if there is a person in the world who thinks he can exhibit the consummation of grace, ease, and eclat in danc- ing, it is the man who is drunk. In consequence of the inequality of alcoliolic paralysis, even on the muscular system itself, the really drunken indi- vidual moves as though he was about to fall in pieces. The inebriate dancer would probably miOve off in sections or separate parts, were it not that his physical body is securely fastened togetiier in spite of himself. The want of l)armony between mind and body, often present, also, no doubt, dis- ables the drunken dancer. Sometimes the muscles act tolerably well in the intoxicated individual, while his mind and will may be in a state of sad confusion. At other times hi5 mind may be fairly clear, while he is limp and helpless on his legs. The musician and the actor likewise fail in the exercise of their callings when intoxicated. The actor is totally unable to depict character by facial expression. The muscles of his countenance are withdrawn from voluntary control. The feature he wants to supply will not come at his bidding — it is something else, something quite different, 182 DISEASES OF INEBRIETY. and yet he is not conscious of the fact. He is deceived by the power of alcohol, and resents the obtuseness and unfair- ness of his critics. The effects of alcohol upon the body of even the casual drinker are always those of a traitor — they always betray. The steadiness and tone of nerve which seem to follow from its use aie only indications of paralysis and insensibility which, deceiving the mind, lure the unwary drinker into danger and disgrace. The late Dr. Jewell gives the following description, which applies in many cases of inebriety : " There is a real, pervasive nutritive lesion of nerve structure in neurasthenia. Waste has morbidly preponderated over repair. The nerv- ous system becomes lean. This involves, necessarily, loss of power and undue sensitiveness or "shakiness " of the nerv- ous system. It is more easily excited than when healthy, and the excitement when once produced radiates farther, and endures longer, than in health. This state or physical condition of the nerve structures differs in degree in various cases or at different times in the same case, from a very slight exhaustion to that which is the most profound. It may extend to the whole nervous system or to only a small part of it, or, if to all parts, unequally so to different parts. It may be in part hereditary, or it maybe acquired. It may affect chiefly the bodily functions, or it may affect chiefly the mental functions, as in some cases of melancholia, or it may involve both at the same time in varying ways and pro- portions, as often happens. There is another condition of neurasthenia which I wish tp place distinctly before you. It consists in a morbidly fluctuating blood-supply to tlie affected parts of the nervous system. The nutritive lesion described seems always to involve an unsteady circulation of blood in the part which has suffered. Especially is the blood-supply likely to fluctuate rapidly, from a too free and tumultuous supply for healthy nutrition, down to a partial anaemia. Nutrition in PATHOLOGY OF INEBRIETY. 183 the part in question is therefore irregular and unreliable. Hence nervous action is unsteady and unreliable. The condition of the walls of the blood-vessels themselves, and of the local vaso-motor mechanisms which control them, in the diseased nervous centres, is much the same as that of the worn nerve elements in the midst of which they are. The local vaso-motor apparatus become worn and ex- hausted, and the muscular walls of ttie vessels in the seat of disease lose their tonus in a measure, and give way before any increase in the blood-pressure with abnormal ease, and this is one of the cliief conditions of a fluctuating circulation of blood in the diseased nervous centres. When it is known how sensitive are the higher nervous centres to changes in the pressure and quantity of the blood circulating in them, it will not be difficult to understand how rapid and extreme fluctuations in blood-suppl}' may give rise to many symptoms, varying according to the function of the part which is the seat of the disorder. CHAPTER XX. PATHOLOGICAL CHANGES IN ALCOHOLIC INEBRIETY. If we consider the serum of the blood in the habitual drunkard as an alcoholized fluid, and that alcohol existing in a certain percentage in the serum acts not only upon the serum of the blood but also upon its anatomical elements, we have a condition that modifies nutrition, producing met- amorphosis and degeneration of tissue. If, in connection with this, we add the fact that alcohol, J>er se, is anarcothie irritant, producing modification as well as degeneration of tissue independent of blood changes, we have an additional reason to regard alcohol as a disease-producing agent. We have, then, to study the pathological effects produced by alcohol on the blood from two standpoints : First. — As to its effect on the blood itself. Second. — The direct effect of the alcohol in the alcohol- ized blood or serum upon the tissues of the body. It would be of interest to determine to what extent the serum of the blood can take up alcohol. That it does so, in common with the other fluids of the body, there can be no doubt. Blood taken from an habitual drunkard, and exposed to heat, will give off the fumes of alcohol. At autopsies on drunkards, the fluid in the ventricles of the brain has been ignited with a match. There is good reason to warrant the conclusion that not only the serum of the blood, but also the fluid of the ventri- cles and the cerebro-spinal fluid, in the case of habitual drunkards, contain alcohol to a greater or less extent, in some cases probably as much as is compatible with life. A 185 186 DISEASES OF INEBRIETY. series of chemical analyses, to determine the average per- centage of alcohol in the blood of habitual drunkards, would be of extreme interest. The blood in such a con- dition has not only its nutritive qualities very much impaired and its oxygenation and circulation retarded, but as a build- er up of tissue it must be very inferior to normal blood ; in fact, it is a disintegrator of tissue. The urine of the habit- ual drunkard contains a certain percentage of alcohol. The application of heat or the proper chemical tests for alcohol, if applied, prove this. Indeed, if we test tlie urine of an abstainer within a reasonable time after he has taken alco- hol, the chromic acid test will show the characteristic reac- tion. The effort to prove that the milk of nursing mothers using beer or other alcoholic beverages did not contain alcohol, has resulted in failure. The toxic effect on the infant is shown in the moderate alcohol coma it experiences after nursing, and where the mother was intoxicated, the convulsions that ensued. The experience of M. Lallemand, Duroy, and Perrin seemed to demonstrate that alcohol received into the body was eliminated by the lungs, the kidneys, and the skin, com- pletely and as alcohol, and that if it was retained in the tissues it was not transformed. The experiments of Anstie, on the other hand, disprove this. "While a certain propor- tion of the alcohol injested is excreted by the lungs, kidneys, and skin, a certain proportion is broken up in the blood and transformed into some otlier substance, prob- ably aldehyde," just as aldehyde shortly after its adminis- tration is transformed in the blood into acetic acid. But this does not weaken the practical fact that alcohol is present in all the fluids of the body, passes through all the excretory organs, acts directly upon the nervous system and other tissues of the body, producing its delete- rious effects either as alcohol or some transformation of it equally pernicious. The degeneration and alteration of tissue in chronic alcoholism is due to the following causes : PATHOLOGICAL CHANGES IN ALCOHOLIC INEBRIETY. 187 First. An impoverished, alcoliolized blood, imperfect in its oxygenation and retarded in its circulation, and, con- sequently, producing mal-nutrition. Second. The direct irritating effects of alcohol contained in said blood. Third. Tlie degenerating effects of alcohol on the nerv- ous centers, producing vaso-motor paralysis and impaired reflex action. The latter is regarded by some writers as the primal and most potent cause of general alcoholic degeneration. The principal tissue changes in chronic alcoholism are falty, fibroid, and atrophic. The most marked examples of alcoholic fibrosis are found in the lungs, kidney, and liver. In the lungs, as alcoholic phthisis, a chronic interstitial pneumonia ; in the liver is cirrhosed, gin, or hobnail liver ; in the kidney as cirrhotic, hard, or contracted kidney. These fibroid changes are slow, may take years to form, but they are rapid in the latter stage. In syphilis we may resolve a gumma or modify the lesions of the tertiary stage. In pulmonary tuberculosis we may be fortunate enough to secure cicatrization of cavities, or hold the disease in check; but the lesions of chronic alcoholism are progressive, and, when once fully established, irremediable, whether in the lungs, kidney, or liver. The effect of chronic alcoholism on the generative func- tions in both sexes is instructive and interesting. " Lippich has demonstrated that alcoholized marriages 1 roduce two-thirds less children than among those who were lemperate. There can be no doubt that alcoholism affects the generative function of both sexes. The testicles undergo degeneration in alcoholized persons. The sper- matic fluid shows this in the well marked changes it exhibits, robbing of the vitality indispensible to concep- tion." "The alcoholic cachexia after it has attained sufficient 188 DISEASES OP INEBRIETY. intensity, will produce this, although the organs themselves may not be diseased. Many examples of women are noted who have had children by their first marriage whose subse- quent union was barren with an alcoholized husband, and also the reverse. Women may become sterile by altera- tions of the ovaries and matrix, and abort before maternity. From this point of view alcoliolism is a more serious trouble in the mother than in the father." Drs. Mairet and Combernal recently presented some experiments on the hereditary influence of alcohol before the Academy of Sciences of Paris. A healthy bitch was made a chronic alcoholic, and gave birth to twelve puppies ; two were still-born, three died b}'^ accident, and the remaining seven died of epileptic attacks, enteritis, pulmonary and peritoneal tuberculosis. The lesions found at the post-mortems were thickening of the bones, fatty degeneration of the liver, adhesion of the dura- mater, and other marked alcoholic changes. A strong bitch was kept intoxicated on absinthe the last three weeks of gestation. Six puppies were born ; three died at birth ; two were of defective intelligence ; one grew up, but was defective in intelligence and nervous organiza- tion. This one was coupled with a healthy dog ; of this union three puppies were born ; one died of marasmus, the other two were congenitally defective, having atrophy of hind legs. One of the conclusions drawn was that the degeneration from alcohol was more prominent in the second generation than the first ; also that alcohol used by the mother always produced defective offspring. A point of interest in this connection is the etiology of dipsomania. The best authorities now agree that, while exceptionally dipsomania may arise from traumatism or alcoholism, the great majority of cases are traced to an insane or intemperate parent or parents. It is a hereditary, not an acquired neurosis. It will be of interest to record further the results of PATHOLOGICAL CHANGES IN ALCOHOLIC INEBKIETT. 189 chronic alcoholism in the lower animals, produced by experimenters with the view of determining the pathologi- cal lesions of alcohol. And none have been more zealous than the French in this direction ; and of these investigators none more prominent or painstaking than M, Magnan, " M. Tardieu has found meningeal haemorrhages in per- sons dying in a state of intoxication. These are less fre- quent in animals, and this is the reason why pachymenin- gitis due to the prolonged action of alcohol is rarer in ani- mals than in man." Magnan. — "That in dogs, even at the end of two months of alcoholic poisoning, the liver undergoes fatty degenera- tion. A microscopic section shows the cells have lost form, are swollen, round, infiltrated with granules and drops of fat." M. Pupier notes the effect on a fowl to which absinthe had been given as a drink ten months. " The liver is hard, resistant, lessened in volume, has irregularities on its two surfaces, numerous whitish depressions, the intermediate parts of a reddish brown color. The microscope shows dilatation of vessels at periphery of lobules, filled with gran- ules ; extreme compression and degeneration of hepatic cells." In another experiment a fowl was subjected to the action of red wine for ten months. " The liver is of a clear yellow color, soft, pasty, and oils the blade of the scalpel. Microscope shows cells enlarged and rounder than normal, filled with granules resembling those in parencliymatous inflammation at its beginning ; here and there large fat drops." A fowl was given white wine under similar conditions. "The liver is of good color, but is shriveled on its lower surface and borders. Microscope shows dilatatiorfi of vessels, which appear three or four times the normal size when compared vvitli the cells which have undergone atrophic degeneration. A rabbit was subjected to alcohol. The 190 DISEASES OF INEBRIETY. liver shows nothing as regards capillary net-work ; the cells are altered and contain two or three nuclei ; around bile ducts there is an increase of connective-tissue nuclei. M. Pupier concludes that absinthe affects primarily the stroma without producing new connective tissue or sclerosis of walls of vessels. This marked new growth has not been con- firmed. As for red and white wine and alcohol, their injurious effect is seen rather in the plasma and hepatic parenchyma," Alcohol would seem to produce hepatic steatosis, but not to the exclusion of sclerosis. A prolonged period of alcoholic intoxication, and conse- quent irritation, might provoke sclerosis. In the same ani- mal, with fatty degeneration of liver, are found irritative lesions, such as pachymeningitis, sclerosis of posterior col- umns of spinal cord, thickening and opacity of arachnoid and pia mater, milky patches in pericardium — all these at the same time. "The kidneys, like the liver, undergo beginning fatty degeneration. The surface is smooth and even ; the cortical substance and prolongation between the pyramids of Malphigi show a well-marked yellowish tint, with small striations of a deeper color. The microscope shows tubuli, slightly swollen, cloudy, filled with granular and fatty epithelium." M. Ruge mentions adhesion of capsule to renal substance in four cases ; in three cases fatty degeneration of the heart. Magnan has seen traces of pericarditis : " The coats of the stomach in dogs who take alcohol mixed with food are not ^ensibly thickened ; but the mucous membrane is injected, rarely ulcerated." When alcohol is taken without food, and directly injected by oesophageal tube or by fistula, traces of violent gastritis are seen ; in one case the stomach was shriveled and thick- ened, and the surface of the reddish-brown mucous mem- brane was H-ned with a layer of thick, sticky, glairy mucus, PATHOLOGICAL CHANGES IN ALCOHOLIC INEBRIETY, 191 Streaked with blood. On cleansing with a stream of water, small ulcerations with irregular borders were seen ; in some places cicatrices appeared as irregular grayish plates. In the mucus were found infiltrations of blood, some in layers, others in small spots. In the same dog, the cord is not in- jected and appears normal ; a grayish tint is seen on the posterior columns, more marked on lower third, where it has the form of a triangle with the base directed backwards on each side of the posterior median fissure ; in the same locality a slight grayish tint in the anterior columns on each side of commissure ; Magan lias noted the same con- dition in a man where chronic alcoholism terminated in general paralysis. Kremiansky, in dogs who were given alcohol four weeks, noticed pachymeningitis. M. Neumann observed the same fact, but also that it did not exist sometimes in a more prolonged use of alcohol. Magnan found slight infiltration and slight thickening of arachnoid and pia matei', but no false membranes of dura mater. Others, slight dilatation of vessels of dura or simple injection or oedema of pia. This diversity is explained by Magnan as due in some cases to a meningeal haemorrhage during drunkenness, a haemorrhagic pachymeningitis ; but while this accounts for the existence of new membranes in some dogs, Magnan asserts " that pachymeningitis may come on without pre- existing haemorrhage in certain nervous affections and chronic alcoholism." We have thus quoted extensively from these French experimenters that others may be encouraged to follow similar researches with regard to the " pathological effects of alcohol " in animals, with the advantage of improved pathological knowledge and modern appliances ; for these investigations demonstrate not only that researches as to the effects of alcohol can be satisfactorily conducted in the lower animals, but they also corroborate what has been 192 DISEASES OF INEBRIETY. demonstrated to be the effects of clironic alcoholism on pro- creation in the human species, as well as its other patholog- ical effects. Alcohol acts not only indirectly through the blood as an irritant, provoking fibrosis or other tissue changes, "but on tlie alimentary canal, particularly the stomach. The local effects of habitual doses of concentrated alcohol are seen in the permanent congestion of the blood vessels, exaggerated or vitiated secretions from tiie gastric glands, and ulti- mately a degenerative change in the structure of the sub- mucous tissues, which consists in the disappearance of characteristic secreting structures and hypertrophic exagger- ation of fibrous tissues." The effect of alcohol upon muscular or other tissue, pro- ducing fatty degeneration, is similar in this respect to the action of phosphorus, arsenic, or other poison. Fatty de- generations of the pancreas from alcoholism shows " the glandular parenchyma has partially or entirely disappeared ; _it may be replaced by adipose tissue, which is developed in the fibrous stroma of the organ around its vessels and glandular ducts." In some instances the acini or charac- teristic gland structure is lost entirely and replaced with fatty tissue. But the most marked evidence of the deteriorating effects of alcohol is seen in its action on the nervous system. "It is clear that the nervous centers, independently of the ill effects on their nutrition of the blood changes, have a certain chemical attraction for alcohol, which accordingly is found in their tissue. "The characteristic changes which have been observed in the brain, medulla oblongata, etc., of confirmed drinkers, consists essentially of a peculiar atrophic modification by which the true elements of nervous tissue are partially re- moved ; the total mass of nervous matter wastes, serous fluid is effused into the ventricles and the arachnoid, while simultaneously there is a marked development of fibrous PATHOLOGICAL CHANGES IN ALCOHOLIC INEBRIETY. 103 tissue, granular fat, and other elements which belong to a low order of vitalized products." From these conditions arise vaso-motor paralysis, with all the results that follow a defective supply of blood and an impaired circulation, tending to local stasis. Moreover, if we exclude traumatism, there is not any disease of the nervous system resulting from other causes than alcoholism, at least with few exceptions, that alcohol cannot produce — alcoholic neuritis, alcoholic anaesthesia, general paralysis, serous apoplexy, etc., and those cerebral conditions from which arise the acute and chronic forms of mental derange- ment. The nerves of special sense are not exempt. " The abuse of alcoholic stimulants has been said to be the cause of amaurosis, and, as a proof of this, tlie fact has been adduced that the affection has been arrested, or even cured, by completely giving up the habit of drinking. Tliis much is certain, that amblyopia occurs in great misproportiun among habitual drinkers. It is generally first seen as night- blindness, but soon becomes constant, and gray atrophy of the nerve is recognized by the ophthalmoscope." (Pagen- stecher.) " One point of interest in this connection, relating to the action of alcohol on the nervous system, is the theory advanced by writers on this subject, and it is a very plaus- ible one : that the degeneration of all tissue in cases of alcoholism is due primarily to the action of alcohol on the nervous centers, and through these, by vaso-motor disturb- ance or impaired reflex action, upon the organs or tissues which these nerve centers, or vessels influenced by them, supply." But it would seem, while regarding this as the prime cause of alcoholic degeneration, we could not ignore the fact that the blood itself was a chronic alcoholism much deteriorated as to its quality and retarded as to its circula- tion, and, moreovei-, tiiat it contained a chemical irritant. The limits of this paper will not permit us to consider in detail all the pathological changes due to alcohol. It affects 194 DISEASES OF INEBRIETY. all the tissues of the body ; even the bones are not exempt. We have therefore generalized our statements and taken a view over the whole field, rather than endeavored to carry out and elaborate any special line of thought. Our object has been to demonstrate that there is abundant material for the pathologist and the microscopist to investigate, and a neglected but nevertheless a rich field for medical research. How little progress has been made in the study of the path- ology of chronic alcoholism and the diseases incident to alco- holism. A general principle may be laid down that, whatever tends to innutrition aims directly at that strength and bal- ance of its forces, that coordination, so to speak, between its peripheral and central portions, that it is needful for the equable discharge of its multitudinous functions. Innutri- tion, by lowering the vitality of the brain-cells, and dimin- ishing the store of power held by the central ganglia from the steady and well-timed responses to all the demands upon them, into spasmodic, irregular, and insufficient sup- plies of the force which it is tiieir province to furnish. But alcohol especially promotes innutrition, and the very stimu- lation which it produces is the surest evidence of its drain upon those reserve forces, that exubei-ance of tlie central nervous fund, that wealth of power which is indispensable to the maintenance of the full vigor, of the constitution during those brief and rare occasions when unforeseen circum- stances shall make unusual demands upon them. Nor is this exhaustion and innutrition all the evil which alcohol works in the constitution. The blood and secre- tions are vitiated and loaded with material foreign to their normal constitution, and there is a universal departure from that almost infinite delicacy of balance, resiliency of the organization, which in the natural healthy state charac- terizes its various portions, to say nothing of that depri- vation of the higher spiritual nature which is the inevitable PATHOLOGICAL CHANGES IN ALCOHOLIC INEBRIETY. 195 concomitant of the habitual deviation from natural metliocls which is forced upon it. Nor is this all of the evil. How unreasonable it is to suppose that children begotten of a parent during such exhaustion of the gangli- onic force — during such prolonged vitiation of the blood and secretions and the perversion of the intellectual and moral forces — should not carry in their physical and spirit- ual natures evidence of the outrage done to natural laws ! CHAPTER XXI. GENERAL CONSIDERATIONS OF TREATMENT, PPfOGNOSES, RESULTS, ETC. Four conditions of cure must be observed. The first condition of cure and reformation is abstinence. The patient is being poisoned and the poisoning must be stopped. Were it an arsenic instead of an alcohol no one would dis- pute this ; so long as the drinking of intoxicants is indulged in, so long will the bodily, mental, and moral mischief be intensified and made permanent. Abstinence must be absolute, and on no plea of fashion, of physic, or of religion, ought the smallest quantity of an intoxicant be put to the lips of the alcoholic slave. Alcohol is a material chemical narcotic poison, and a mere slip fias, even in the most sol- emn circumstances, been known to relight in the fiercest intensity the drink crave which for a long period of years had been dormant and unfelt. The second condition of cure is to ascertain the predisposing and exciting causes of inebriety, and to endeavor to remove these causes, which may lie in some remote or deep-seated physical ailment. The third condition of cure is to restore the physical and mental tone. This can be done by appropriate medical treatment, by fresh air and exercise, by nourishing and digestible food given to reconstruct healthy bodily tissue and brain cell, aided by intellectual, educational, and other influences. Nowhere can these conditions of cure be so effectually carried out as in an asylum where the unfortun- ate victim of drink is placed in quarantine, treated with suitable remedies until the alcohol is removed from his sys- 197 198 DISEASES OF INEBRIETY. tem, then surrounded by elevating influences, fed with a nourishing and suitable diet, and supplied with skillful medical treatment. His brain and nervous system will then be gradually restored to its normal condition, and, after a period of from six to twelve months in most cases, he will be so far recovered as to be able to return to his usual avocation and successfully resist his craving for drink. In the cttre of inebriety there is probably more agitation and interest than ever before. The efforts of societies and parties, of the pulpit and rostrum, with the increasing books and papers from the press, have never been more active than to-day. Yet reports show that inebriety is increasing, and that more spirits are made and consumed every year. All the temperance efforts and legal means for the cure and prevention of inebriety are based on the theory that it is a moral disorder which the victim can control at will, or a wicked habit that he can continue or put away at his own pleasure. This theory of inebriety is theoretical, and embodies the same error which follows every new advance of thought, namely, explaining all human action from some moral or theological standpoint. Thus the phenomenon of insanity was explained as a possession of tiie Devil, and the victims were supposed to enter into a compact with evil spirits, voluntarily. The remedy was severe punishment. Public attention was occupied for ages in persecuting and punishing the insane and epileptics on this tiieory of the causation. Law, religion, government, and public senti- ment, all failed in the cure and prevention by this means, and these diseases went on unchecked, simply because the real causes were unknown. Inebriety is regarded in the same way as wickedness, and the same means are urged as a remedy. Over five liun- dred thousand inebriates were sent to jail in iSgi.and pun- ished as willful and voluntary drunkards. Armies of moralists and temperance people are pledging and praying GENERAL CONSIDERATIONS OF TREATMENT. 199 the inebriate to stop drinking, and exercise his will, and be temperate and well again. Yet all such efforts fail, and often tend to increase the very condition which they seek to remedy. They fail because they are based on a false assumption of the causes, and not on any accurate study of tlie history or real con- dition of the patient. A new era is dawning for the inebri- ate. His diseased condition, and the need of special medical care in special surroundings, is a truth that is spreadingslowly and surely in all directions. Not faraway in the future inebriety will be regarded as small-pox cases are now in every community. The inebriate will be forced to go into quarantine and be treated for his malady until he recovers. The delusion that he can stop at will, because he says so, will pass away. Public sentiment will not per- mit the victim to grow into chronic stages ; the arhiy of moderate and periodic drinkers will be forced to disappear, and the saloons which they have supported will close in obedience to a higher law than any prohibition sentiment. Public sentiment will realize that every inebriate is not only diseased, but dangerous to society, to himself, and all his surroundings, and demand legal guardianship and re- striction of personal liberty until he recovers. When these poor victims realize that society will not tolerate their presence or allow them personal liberty in this state, they will seek help and aid before they reacli extreme stages. This is the teaching of all modern science, — to check the disease at the beginning, to seize the poor waif on the street and the rich man's son, who are just at the beginning of inebriety, and force them into conditions of health and sobri- ety, to save the one from becoming a prey on society and a burden to the producer and tax-payer, and the other from destroying society and himself and leaving a tide of misery and sorrow that will continue long after. When society shall realize and act on these facts, the great centers of pau- perism and criminality will be broken up. This will be 200 DISEASES OF INEBRIETY. accomplished by the establishment of work-house hospitals, where the inebriate can be treated and restrained. Such places must be located in the country, removed from large cities and towns, and conducted on a military basis. They must have all the best appliances and remedial means to build up and restore the debilitated victim. They should be military training hospitals, where all the surroundings are under the exact care of the physician, and every condi- tion of life is regulated with steady uniformity. Besides the medicinal and hygienic treatment, there should be educational and industrial training, and each one should be 'employed, both in body and mind, every day. He should be placed in a condition for the best culture and building up of the entire man. Every defect of body and mind should be antagonized and remedied as far as possible. Each case sliould be an object of study to ascertain the real state and the means to strengthen and improve it. These hospitals should be built and conducted entirely from the license fund or the taxes on the sale of spirits. They should, in a large measure, be self-supporting from the labor of the inmates, and independent of the tax-payers. These places would most naturally divide into three distinct grades. The first class of hospitals should be for recent cases, where the inmates can be committed by the courts, or voluntarily com- mit themselves for one or two years. The second class should receive chronic cases for longer terms of treatment — from one to three years. The third class should be for the incurables, or those who give no reasonable promise of restoration. The time should be from five to ten years and life. The latter class should be thoroughly organized into military habits of life and work, and kept in the best con- ditions of forced healthy living. Employment and mental occupation should be carried out literally as a stimulus to strengthen the body and mind. Where it was possible the rewards of his labor, beyond a sum to pay for care, should GENERAL CONSIDEEATIONS OE TREATMENT. 201 be turned over to his family and friends or held in trust for him. He should be encouraged to healthy work and living by all possible means and surroundings. The semi- chronic cases should be treated substantially the same way, only occupation and training of the mind and body should be more suited to the wants of each case. The amusements should also be of a sanitary character. The recent cases should have the same exact discipline, filling the mind with new duties and new thoughts, and suited to build up the exhausted, overworked man, as well as the gormand and under-worked idler. All persons should pay for their care if possible, and be required to render some service which would be credited on their bills. These hospitals should be literally quarantine stations, where the inebriate can be housed and protected and society saved from the losses following his career. If ten thousand poor chronic inebriates could be taken from New York and placed in such hospitals, and made self- supporting, who could estimate the gain to society, to morals, to the tax-payer, and to civilization ? This can and will be done in the near future. If ten thousand semi-chronic cases of inebriety could be taken from New York and quarantined two or five years in such military hospitals, and made to pay for their care by labor, who could estimate how many would be returned to health and temperate liv- ing again ? — who could estimate the relief from sorrow, misery, wretchedness, and losses ? This will also be a reality a little fartlier on. If ten thousand recent cases of inebriety could be taken out of their surroundings in New York and placed in these hospitals, where forced conditions of the highest degree of health and vigor are maintained, a large percentage would recover. The gain to society and the world would be beyond all computation. Now each one of these propositions and the practical working of a military hospital is a reality, based on evidence constantly accumulating. Every prison, penitentiary, or hospital, every 202 DISEASES OF INEBEIETT. asylum or home where inebriates come under care and restraint bring such evidence. They show that such a method of treatment, combining the varied experiences of all these institutions can be made practical and is the only scientific way of solving this problem. To banish the still and saloon does not prevent inebriety or cure the inebriate ; it only changes the direction of the drink current. But quarantine the inebriate in a hospital, as one suffering from contagious disease, and the victim is cured, the spread of the disease is prevented, and a knowl- edge of the causes ascertained, from wiiich the remedies can be known and applied. To punish the inebriate as a criminal cannot cure his inebriety, but it always unfits him for living a temperate, healthy life hereafter. To attempt a cure by faith and prayer is to depend on false hopes, the failure of which is followed by increased degeneration. To attempt any form of treatment without knowing any other fact except that the victim drinks to excess is always to blunder and fail. The time has come to recognize the physical conditions which enter into all cases of inebriety, and to apply exact remedies along the line of nature's laws and forces. The late Dr. Bellows, in an address delivered in 1858, said : " Inebriates, like criminals and insane, will all be eventually restrained in hospitals, and treated with medical and psychological skill the moment their liberty becomes dangerous to society. The terms of their confinement will be limited only by the possibilities of cure and tiie con- ditions of their disorder. Society gains nothing by holding prisoner for an hour any man who is fit to be at large. Liberty and human rights gain nothing by allowing anv man to be at large for a moment who is destroying himself, his family and his neighbors. What we need is what we are fast gaining, namely, a possession of the tests and gauges of the fitness and unfitness, and we shall be able to GENERAL CONSIDERATIONS OF TREATMENT. 203 treat the inebriate successfully the same as in other dis- eases." Sorne general idea of the details of treatment will be of interest. In a hospital conducted on scientific common- sense principles the patients are received for periods of not less than three or six months. The patient signs a commit- ment paper, and is examined by the physician, and all the facts of his present and past condition noted. If intoxi- cated he is placed in charge of a nurse and baths and remedies given for his special condition. If sober he is given a pleasant room and placed upon a regular diet, exact conditions of living, and required to take such medicines, baths, exercise, and general treatment as may be needed in his case. Mental occupation, amusement, change of thought and life in every particular are sought for. He is treated as one u'ho has a profound disease of the brain and nervous system, requiring rest, care, and removal from every source of irritation and excitement. The question of responsibility to aid the efforts of the hospital in his behalf is urged as a S5'mptom of his capacity or incapacity to recover. The asylum is a quarantine where he can recover, and his liberty or restraint is governed by his condition. Wherever congenial work can be added to the amusement it is done as a medical aid. Every condition of life is controlled and regulated, and every surrounding arranged to aid recovery. Daily religious exercises, rides, walks, Turkish baths, and exact methodical living, most naturally result in a degree of strength and vigor that is very promising for the future. To accomplish this the asylum must be pleasantly located, the building must be cheerful and sunny, and adapted to the work. The surroundings must be free from all sources of irritation and unpleasantness, such as noise, excitement ; and the management must seek to apply remedies to meet the wants of every case. Thus, in some instances, sharp restraint is a tonic remedy of value ; in others it is depress- ing. In some cases nerve rest and regularity of living is of 204 DISEASES OF INEBRIETY. more value than all other things. The physician finds from a study of each case a most bewildering complexity of causes, beginning with heredity and including every- thing which produces distinct strain or drain on the nerves and brain. The great object of all inebriate asylums is to practi- cally quarantine the inebriate, where all the exciting causes are removed, and every predisposing cause is antagonized, and where the most favorable conditions for rest and build- ing up can be secured. The remedies to aid in this work are indicated by the special condition present, and include all the nerve and brain tonics, the common property of the profession. The physical remedies, are diet, baths, exercise ; and the mental remedies, including mental occu- pation, amusement, change of thougiit and mind, growth out of the past, are all essential and equally valuable. Restraint and freedom, rewards and punishment, appealing to the will and ignoring it, etc. Rules and regulations for every act of life ; few rules, which the patient applies him- self, and so on, using the most diverse means which would apply to the special need of each case. The condition or disease to be treated is a profound physical disordei", and the toxic use of alcohol is always a symptom as well as a cause. The best efforts of science is to break up this cause, and change the symptoms. The defects continue, the man is permanently impaired. He may go back to active life and do well, but ever after, as a rule, the same range of causes will produce the results. In a certain number of cases the drink impulse or symptom seems to be permanently exiiausted after a time like the exhaustion of the germ soil of some diseases, and no exciting causes will develop the drink symptoms again. Other defects may appear, but he never again uses spirits. The germ soil has gone, it may be forever, or after lapse of years it will return. A period of six or twelve months in an asylum will re- GENERAL CONSIDERATIONS OF TREATMENT. 205 move the states of delirium which have kept up the use of alcohol, and reveal an exhausted brain and nerve soil that will not tolerate alcohol in any form after. The person sud- denly realizes that alcohol is both poisonous and repelling to his system. This may be so intense that should he take any form of spirits by mistake it will produce intense nau- sea and depression. In other cases the drink exhaustion dies out after long years of abstinence, and should the pa- tient relapse late in life, death follows soon after. A care- ful study in an asylum often reveals these cases, and the expert can safely predict a total or partial cure of the drink symptoms and disorder, or its temporary suppression, only to break out again. Another fact, not generally known, appears to the asylum physician, namely the great uniform- ity of the symptomology and progress of these cases. Be- ginning at a certain point, or from certain range of causes, they follow a uniform line of progress, which can often be seen, traced, and predicted with certainty. In an asylum the stage of progress can frequently be seen, and means for its prevention or diversion can be applied. In an asylum all tlie conditions of life can be reg- ulated ; the food, the surroundings, the pei'iod of rest and activity ; the mental states can be antagonized or prevent- ed ; the local condition from which irritation is produced can be removed ; the physical irritation which keeps up the drink impulse is changed. The asylum treatment, like the quarantine for contagious disease, isolates the victims from all exciting and predisposing causes, and thus places him in the best possible condition for returning health. Asylum and medical treatment for the inebriate are most impera- tively demanded, not only to save the victim, but to enable us to understand some of the great underlying causes which are active in precipitating so many men into this terrible disease. Primarily in the treatment we have shattered constitu- tions, and broken-down nervous systems to deal with. We 206 DISEASES OF INEBEIETY. have a disease eminently marlced by weal^ening of the will- power, and seclusion from society, rest, judicious restraint, and enforced abstinence from ail alcohol stimuli are car- dinal points of treatment. I always let patients, applying to me for treatment, distinctly understand that a permanent recovery depends largely on allowing sufficient time for restoration of nerve-power, mental tone, and physical vigor, and I think, in most cases, six months is the least time nec- essary for a complete recuperation of the will-power. Dip- somania is a disease that requires the most perfect disci- pline, both moral and physical, if we expect a cure. Peri- odical insanities are notably difficult to cure so that there is no chance of a relapse, but we may reasonably expect an ultimate cure if there is but little structural change in the brain which has resulted from the course of inebriety. The heart's action in dipsomaniacs is weak, often irreg- ular, accompanied by palpitation. There is a loss of tone in character, blunting of moral perceptions, impairment of intellectual discrimination, and generally impairment of all the mental faculties. There is very often an utter inability to fix the mind on any one subject, or to follow up a train of thought consecutively. We see periods of abnormal cerebration ; an instantaneous abeyance of reason and judgment ; a condition resembling an epileptic state, dur- ing which period the inebriate may be actuated by mad, ungovernable, or eccentric impulses ; a condition in which disease has deprived him of the power of choice, and during which states, in my opinion, the inebriate is as little respon- sible for his actions as is a person suffering from any other phase of mental disease. I knew a gentleman of high social standing in this city who has these mental blanks, during which time he rides up and down New York in a horse-car, aimlessly, and has no recollection afterward of having done this at all. These are very interesting cases from a medico-legal point of view. In these cases the healthy coordination of GENERAL CONSIDERATIONS OF TREATMENT. 207 ideas is destroyed for the time, and tlie patient need not be alcoholized to liave such states occur. In cases of inebriety or dipsomania we liave to deal with the results of a toxic poison, and we may have various complications proceeding from the abuse of alcoliol, such as cirrhosis of the liver, gastritis, epilepsy, various forms of dyspepsia, and in some cases with Bright's disease. We may also find a simple hypertrophy of the left ventricle of the heart, and degen- erated arteries. Our patient must have cheerful, tranquil, and pleasant surroundings ; all cerebral excitement must be repressed ; sleep must be procured ; plenty of nourishing, easily digested food administered at sliort intervals, and an abundance of fresh air and exercise. I am not in favor of much meat in tlie diet list. Certainly none at all, except at dinner, and I think a strict diet list, so that the work of the liver and kidneys is diminished by lessening the amount of highly nitrogenized food and of the hydro-carbons, gives decidedly the best result. Fish, oysters, and fruits that con- tain sugar, the green vegetables, bread, wheaten meal, and oatmeal are all permissible. Potatoes should be eaten somewhat sparingly, and eggs also. Poultry and the white meats are well borne. Beef and mutton are not so well borne, and are contra-indicated, except at dinner. Exercise in the open air is indispensable. The action of the skin must be stimulated, and systematic skin friction w^ith cold sponge or shower baths do much good. Also the Turkish bath is useful. The natural saline mineral waters are the best to stimulate excretory action by the abdominal organs. The Hunyadi-Janos, Friedrichshall vi^ater, and Saratoga Congress water are the best, while foi' diuretic waters, Saratoga Vichy and Apollinaris water arc the best. We have a worn, irritable condition of the nervous system in inebriates, an unstable condition as regards its nutrition, its solidity, and its perfection of structure. We must supply the greatest amount of nutritive material to the 208 DISEASES OF INEBRIETY. brain and nervous system to repair the existing nutritive lesion. We must supply the phosphates in some way, the many eligible preparations containing them being familiar to you all. All abnormal nervous excitability must be quieted, and our patient kept calm and tranquil. A pro- longed warm bath at night, followed by the administration of one teaspoonful of the ammoniated tincture of lupuline, or of a pill of camphor, ext. hyoscyamus, and pulv. digitalis will often quiet the nervous excitability. Care must be given to the excretory functions of the skin, kidneys, and bowels. If there is headache and drow- siness, such diuretics as the liq. ammoniac acetat., w'ith spt. nitric ether are indicated. Indian hemp has proved itself in my hands a valuable adjunct, in doses of X gr. of the extract, as required. A very valuable sedative mixture is one composed of 30 grains of bromide of sodium and 30 minims of tinct. of cannabis indica prepared with water, at the time required. It induces calmness and tranquility, and can be repeated thrice daily, if required, without the loss either of flesh or appetite. One of our most valuable remedial agents in inebriety is phosphorous, which I always give in i-ioo to 1-25 gr. doses in cod liver oil after meals. Cod liver oil is one of the best nutritive remedies, as fat must be applied to the nutrition of the nervous system if this is to be maintained in its organic integrity. The general effects of phosphorous are those of a stimulant, but it pos- sesses a special power over the exhausted nervous system. It is perhaps evanescent in its effects, but is never followed by a stage of depression wdiich is noticable. It should never be ordered upon an empty stomach. A pill of iron, phosphorous, zinc, and strychnia is also very useful, and combinations are often more beneficial than the medicines when taken singly, A large percentage of all cases of inebriety, before admission into our institutions for the cure of inebriety, have passed through the primary and acute stages, and liav^ GENERAL CONSIDERATIONS OF TREATMENT. 209 probably been subjected to medical treatment. This fact must never be lost sight of in forming our opinion, not only of the nature of the disease itself, but of the medical treat- ment necessary for its cure. We often discover that the dipsomania has been allowed to exist and slowly progress for a considerable period, no treatment, either medical or moral, having been adopted for its removal. The most simple classification of inebriety, the one best adapted for useful and practical purposes, is its division into the acute, periodic, and chronic forms. The acute form is the rarest, and is ushered in by exhausting diseases, or excessive sexual excess. The periodic form is much more frequent, and it is to this form of inebriety that I would recommend the term dipsomania to be restricted. It is frequently hereditary, like all insanities, and strictly periodic in its paroxysms. These patients — dipsomaniacs — may abstain for weeks or months, and may during this interval positively dislike stimulants. The last or chronic form of inebriety is very incurable, as the patients are incessantly under the desire for alcoholic stimulants, and will get them if any opportunity occurs, whereas the dipsomaniac have only the irresistible craving for stimulants periodically. It is in these cases of chronic inebriety that we find hallucinations of sight and hearing, very painful moral impressions, confusion of thought, suicidal tendencies, tremors of the facial muscles and tongue, and very often paralytic symptoms, ending in gen- eral paralysis. It is here, in chronic inebriety, that disease of tlie brain may destroy all apparent consciousness of pain, and keep in abeyance the outward and appreciable mani- festations of the important indications of organic mischief. Extensive disease of the stomach, lungs, kidneys, bowels, uterus and heart have been known to have progressed to a fearful extent without any obvious recognizable indication of the existence of such affections. The most essential preliminary matters for inquiry 210 DISEASES OF INEBRIETY. relating to the treatment of inebriety, have relation to the age, temperament, previous occupation and condition in life of the patient. It will be necessary to ascertain the character and duration of the attack, to ascertain whether it has resulted from moral or physical causes ; if of sudden, insidious, or slow growth ; whether it has an hereditary action, or is the effect of a mental shock or of mechanical injury ; whether it is the first attack, and if not, in what features it differs from previous paroxysms. It will also be our duty to inquire whether it is complicated with epilepsy, insanity, suicidal or homicidal impulses. If any prior treat- ment has been adopted we must learn its nature ; whether the patient has suffered from gout, heart disease, rheuma- tism, skin disease, or syphilis. It is important in cases of females to obtain accurate information in relation to the condition of the uterine functions. We should also inquire whether the patient has been suspected of habits of self- abuse. Having obtained accurate information upon these essen- tial points, our own personal observation will aid us in ascertaining the character of the inebriety. The configura- tion of the head, chest, and abdomen ; the gait of the pa- tient ; the degree of sensibility and volitional power mani- fest ; the state of the retina, the pulse, the temperature of the head and body ; the condition of the skin and chylopoie- tic viscera ; the action of the heart, lungs, and nature of any existing disease of the uterus should be noticed. Onv prog- nosis in cases of inebriety will mainly depend upon the dura- tion of the attack, its character and origin, and the diathe- sis of the patient. The prognosis is unfavorable if the disease is hereditary. Age materially guides us in forming a correct prognosis. The greater proportion recover be- tween the ages of twenty and thirty-five. When a patient has youth and a good constitution, and remedial measures are promptly applied to the patient while he is secluded GENERAL CONSIDERATIONS OF TREATMENT. 211 from all occasion of temptation, the prognosis is favorable. I have seen patients after forty and fifty recover. The prognosis is unfavorable when inebriety is associ- ated with organic disease of the heart or lungs, or when great impairment of mind, associated with paralysis, is pres- ent. Prolonged hot baths are of the utmost service in the treatment of inebriety. Among the therepeutic effects of these baths I would mention a diminution of the circulation and respiration, relaxation of the skin, alleviation of thirst, the introduction of a good deal of water into the system, an abundant discharge of limpid urine, a tendency to sleep, and a state of repose. It is most useful in acute and chronic inebriety. The preparations of hyoscyamus, conium, stra- monium, camphor, hops, aconite, ether, chloroform, and Indian hemp are all of great service if given with judgment. The best plan in practice would seem to be to judiciously combine various kinds of sedatives. Milk heated almost to boiling is very valuable. It allays irritability of the stomach and craving for stimuli, and two glasses at night have a very sedative effect. If there are decided signs of cerebral congestion the occasional application of a leech behind the ear is good practice. If symptoms of softening of the brain appear they will often yield to the persevering use of the prepara- tions of iron, phosphorous, zinc, and strychnia, with gener- ous living. Strychnia antidotes, it appears to me, slight impairment of the mind, loss of memory, defective power of attention in inebriety very perfectly, and may be combined with two gr. doses of quinia thrice daily. If inebriety is associated with suicidal tendencies it will be important to ascertain whether any cerebral congestion exists, and if so, a few leeches applied to the head, followed by an active cathartic, will relieve the local irritation. In the absence of any positive active cerebral symptoms, the prolonged warm bath and the continued exhibition of morphia will be the best treatment until the suicidal idea disappears. 212 DISEASES OF INEBRIETY. We need both State and national hospitals for the cure of inebriety, places of detention or asylums, under the care of medical officers well trained by preliminary educa- tion for their vocation, and acquainted thoroughly with inebriety. One of the best remedial agents whicli can be employed in inebriety is electricity. Both the constant and induced currents, or galvanic and Faradic electricity, may be used. Electricity is a true nerve tonic, and it is an agent which furnishes us with the means of modifying the nutritive con- dition of parts deeply situated, and of modifying the circula- tion to a greater extent, I think, than by any known agent. By the judicious employment of the constant and induced currents we have it in our power to hasten the processes of nerve growth and nerve repair, and thereby hasten the acquisition of nerve power. The use of electrictity does not, I think, act by contribut- ing anything directly to the growth or repair of nerve tissue. Its action is to stimulate and quicken those pro- cesses on which the material and functional integrity of the nervous system depends. The use of electricity in inebriates is always followed by an increase of strength and nerve force, and the results gained are gradual and permanent. Dipsomania or periodical inebriety is characterized by abnormal nervous excitability, conjoined with cerebral exhaustion, and the two indications which are urgent are, primarily, for increased rapidity and effective- ness as regards the process of nerve nutrition, and second- arily, to secure freedom from excitement, and diminution of nerve activity, and thereby to check the waste of nerve structure and of power. These indications we can fulfill by the judicious use of electricity and nerve tonics more cer- tainly than by any other means, there being no other such combined sedative, restorative, and refreshant to the central nervous system. To give the brain the direct nutriment it GENERAL CONSIDERATIONS OF TREATMENT. 213 needs in inebriety, I Iiave before stated, can be accomplished by rest, cod liver oil, phosphorus, the phospliates, etc. Every intelligent person who has observed the march of human thought into the recently explored realms of Psycho- logical medicine and the treatment of mental diseases, will get new views as to modes of treatment, more especi- ally of that class for whom institutions were organized. The favorable results of each succeeding year, only confirm and demonstrate the truth of the humane and wise idea that led to the organization of institutions, viz. : that intemperance in all its stages may be not only checked and mitigated, but in many instances permanently cured, and the subject fully restored to his normal condition of health and sobriety. Such results may not be reached by the final and utter extinction of the morbid desire for alcohol, so much as by a development and cultivation of opposite and ennobling qualities, which by their vital action, hold the depraved mental tendencies of the subject in constant and absolute subjection, so that they become as inoperative as if they did not exist. This is as near an absolute cure as we can hope to reacli, as the testimony of all inebriates concurs in the fact that the appetite for intoxicating drink never dies, though it may be put to a life-long sleep. It cannot be expected that the final and complete results of the treatment of our patients, so variously circumstanced and conditioned, can be fully known. From this common center of reform, hundreds have struck out in new and divergent paths, and are lost to our view in the general whirl of business and laudable enterprise. Whenever any one does fall into his previous habits, we are certain to be informed of the fact, as few things travel so fast and so sure as ill-tidings of man's vices and misfortunes. We can congratulate ourselves on the fact that thousands who have been under hospital care are now in active life 214- DISEASES OF INEBRIETY. all over the country, of wliose doings we are cognizant, and it is a source of pleasure to us to know that their correct and consistent conduct is productive of liappiness to them- selves, and does iionor to the institutions and the humane work which it has in hand. CHAPTER XXII. ASYLUMS AND THEIR WORK IN THE TREATMENT OF INEBRIETY. Asylums and hospitals for the treatment and cure of inebriates are only modern applications of truths asserted centuries ago. Ulpian, tlie Roman jurist, in the second cen- tury of the Cliristian era, urged the necessity of treating inebriates as sick and diseased, in special surroundings, with special means. Other authorities indorsed these views, and asserted that the State sliould recognize the veritable mad- ness of drunkards and treat tliem as such. In 1747 Condillac, of France, wrote that the State should provide special hospitals for drink maniacs, and urged a change of law and public sentiment to this end. Dr. Rush of Philadelphia, in 1790 ; Dr. Cabanis of Paris, in 1802 ; Prof. Platner of Leipsic, in 1809 ; Salvator of Moscow, in 1817 ; Esquirol of France, in 1818 ; Buhl Cramner of Berlin, in 1822, all urged the need of physical restraint and treat- ment of the inebriate as sick and diseased, in places espec- ially provided for this class. In 1830 the Connecticut Medical Society appointed a committee to report on the need of an asylum for the medical treatment of inebriates. In 1833 Dr. Woodward, of tlie Worcester Insane Asylum, in Massachusetts, urged that inebriety be recognized as a disease, and special hospitals be provided for its treatment. In 1844 the English Lunacy Commission urged that inebri- ates be regarded as insane, and sent to asylums for special treatment. These are only a few of the more prominent references to inebriate asylums, although many other 215 216 DISEASES OF INEBRIETY. writers urged the same views in different ways. The men- tion of tlie disease of inebriety roused a bitter opposition, and the question of asylums was put aside until the former could be settled. In 1846 Dr. Turner began an entliusiastic agitation, which culminated in the first asylum at Binghamton, New York. The opposition to this work was very intense, and came from moralists, who urged that it was a purely " infidel work " to diminish human responsibility. Tlie asylum at Binghamton began on the most advanced principles, of receiving no one for less than one year, and having abso- lute restraint over them during this time. It asked no pledges or promises from the patient ; it aimed to give each one positive protection and medical treatment. The patients were locked in at night, and only allowed out under the strict care of attendants. Each case was consid- ered a suicidal case of insanity, requiring long medical care and restraint. These methods were far in advance of that time, and even to-day are just beginning to be recognized as the latest teacliings of science. The patients themselves, after the immediate recovery from the effects of spirits, protested against the confinement and doctrine of disease, and sought in every way through their friends to break up the methods of treatment. The points of difference were these : The asylum and management insisted that each case was more or less diseased, and should be under absolute control and restraint for long enough time to effect a permaraent cure. The patients and their friends insisted that, while the case might be diseased, his recovery depended largely upon his liberty and promise to get well ; that restraint was irrita- tion and injury; and that appeals to his honor and man- hood were the real agents for final cure. In brief, one plan proposed long restrain ; the other, no restraint except nom- inal care at first, then persuasion and advice. ASYLUMS AND THEIR WORK. 217' The board of management changed, and the central object was to make the asylum popular with the patient. Political controversy followed, and the State changed the asylum to an insane hospital, and a political governor, in justification of the act, called the inebriate asylum a failure. , The asylums in this country for the treatment of inebri- ates may be divided into three classes. ist. Those hospitals which have been established by cor- porations receiving State aid, or by private enterprise, and incorporated, having the advantage of the laws, where the inebriate is regarded as diseased, and treated on broad sci- entific principles. 2d. Hospitals, both corporate and private, wnere the inebriate is admitted with other cases of mental disease ; mild maniacs, and eccentrics of all degrees of debility, of both mind and body. Here the inebriate is treated from some mixed theory or half disease and half vice ; when he has recovered from the acute symptoms, is held as fully sane and responsible. The third class of hospitals ignore all question of disease except that which comes from the direct use of alcohol, which from their theory can be quickly remedied. The treatment of the case is by the pledge, prayer and promise. The first class of hospitals endeavor to apply real scien- tific means of treatment and study of these cases, much the same as in other cases of insanity. The second class combine and treat these cases with other mental diseases, without any special study or recogni- tion of tiieir nature or character. The first persons who come to these asylums are the in- curables. They clamor most importunately for help. They are the credulous, emotional incurables, who have signed pledges, joined churches, and tried every means known, and now expect from the asylum some miraculous power of restoration. In a few weeks they believe themselves fully recovered, and go away only to relapse again and become 218 DISEASES OF INEBRIETY. bitter enemies of the institution. This class appear every- where as examples of the failure of the liospitals. An- other class of incurables come from the better ranks of society, often for the purpose of accomplishing some object, consent to go anywhere and do anything that promises relief or restoration. These moral paralytic inebriates rouse the highest expectation and greatest enthusiasm in the grand work of asylum-cure among their friends, and pose as examples of " brands rescued from the burning," then suddenly relapse and condemn the asylum and man- agement as the cause. The humbug of the asylum, its frauds and deceptions, are themes of great relish and pleas- ure to them, A second class of persons are coming in greater numbers every year to these asylums. They are the cuiable cases, — the nerve and brain-exhausted men and women, the large and ever-increasing class of business and professional men, who have broken down from overwork, worry, and irregu- larity of life and living, and who find alcohol a narcotic of most seductive nature. The still laiger class seen in every city of the land, who from brain strains and drains incident to the rushing, grinding civilization of to-day, also to the struggle for position, wealth and power, and tiie effort to adapt themselves to the new conditions of life, to the new demands, thus prepare the soil by exhaustion, and encourage the growth of inebriety and its allied diseases. This class often represents the highest talent and genius, and, as a rule, are the active brain-workers of the times. An ine- briate hospital to this class is almost an " el dorado." It brings rest, restraint, seclusion, building-up, and is literally a place for repairs and restoration. In this class the use of alcohol, opium, or any other nar- cotic is often more of a symptom of exhaustion and debility, for which rest and medical care are essential. There are many thousands of this class who could be saved and perma- nently restored to temperate life and living if they could ASYLUMS AND THEIE WORK. 219 be placed in inebriate hospitals and treated early. Later, they become clironic and incurable, and are ever after a burden and heavy loss to the world. To-day they cannot go to an insane asylum, and tlie public hospital is unfit for them, and no place is open adapted to reach tiieir wants. A large army of tliese curable cases are scattered in ever)^ community, and in almost every home; and are the skeletons which haunt and peril the peace of many house- holds. They are tlie secret and moderate drinkers. They are those who have secret or open drink paroxysms, and who recover only to relapse again whh steady increasing frequency. Both men and women in all circles of life are found in this army of dissolution. Moral remedies fail, religion fails, they go steadily down and soon all fears of publicity are thrown aside, and the march to death is rapid and distinct. Not far away in the future, asylums and hospitals will be opened to save these cases, and public sentiment will demand that they be placed under treatment early in the progress of the case. Of this class a very large number are curable, and all are benefited by hospital residence. A third class comprises the erratic border liners, or per- sons who alternate up and down the line of sanity and insanity, whose genius attracts by its glitter, and bewilders by its weakness. They sound the praises of the asylum far and near, exaggerate its power, and claim the most extra- ordinary results, then rush to tiie other extreme on relaps- ing, exliibiting a malice and pleasure in destroying what they so lately praised. Others who are less incurable appear, but always wish to decide the lengtii of tiieir treatment, then go away only to relapse and attribute the failure to the asylum. In addition to all this, public sentiment often gives credit to these statements of incurables, and hence withholds the sympathy and aid wiiich should be given. In many cases the State refuses to give only limited authority to the man- 220 DISEASES OF INEBRIETY. agers to hold patients. And in other cases the clergy and temperance reformers insist tliat prayer, conversion, and the pledge shall be made prominent in the treatment. Thus tlie most extraordinary misrepresentations, extrav- agant credulity, and ignorant criticism follows every movement of the institution. The superintendent and the managers are never able to carry out their plans fully, or bring out the real object and methods of obtaining it with these cases. The results of treatment in a few scientific hospitals for inebriates are most encouraging. The first statistical study was made at Binghamton Asylum in 1874. The object was to find out how many persons who had been under treat- ment continued temperate years after. Accordingly, over a thousand circular letters were addressed to friends of patients who had been under treatment five years before, asking the present condition of the patient. The answers indicated sixty-two and a-half per cent, as yet temperate and total abstainers. This result, after an interval of five years, was clear evidence that a large per cent, would remain cured during the remainder of life. Dr. Day, of Washingtonian Home, made a similar study of eight thousand cases who had been under treatment ten to eighteen years before, and found over thirty-eight per cent, yet sober and temperate. Dr. Mason, of King's County Home, examined two thousand cases who had been away from the asylum for ten years, and found thirty-six per cent, of all cases yet cured. Other observers have made studies of a smaller number of cases with similar results. Not less than two thousand inebriates are under treat- ment in hospitals in America. Over a thousand of this number are in special hospitals. They represent most largely the incurable cases ; persons who have tried every means found in the pledge, prayer, and by moral suasion, and exhausted every resource of home and friends, and come as a last resort, expecting extraordinary change and ASYLUMS AND THEIR WOKK. 221 cure. Tliey have been victims of this disease from five to thirty years, and present tlie most complex and varied de- grees of physical and mental degeneration. Yet, notwith- standing this fact, the experience of the few scientific hos- pitals in the results of treatment is exceedingly promising. Statistics of over three tliousand cases, wliich have been under treatment at different hospitals, indicate nearly forty per cent, restored and temperate after a period of six to eight years from the time of discharge from the hospital. The best authorities unite in considering thirty-five per cent, of all who remain under treatment one year or more as permanently restored. In view of the chronic character of these cases, and the imperfect means of treatment, these statistics are encouraging, and indicate great possibilities in the future from a better knowledge and control of these cases. Legal Control of Inebriates. — The legal control of the ine- briates in America, and legislation, are very imperfect. In Connecticut the best laws are in force, giving power over inebriates to voluntarily commit themselves, or be com- mitted by tiieir friends, without the formality of appearing before a judge or court. In other States they are com- mitted to asylums in about tlie same way as the insane are. In the hospitals they are controlled legally the same as the insane, only with more difficulty, and the constant intrusion of disputed questions of authority which cannot be settled. Nearly all the leading hospitals have special powers of control, which they exercise with caution in most cases. But generally both legislation and legal authority are not far ahead of public sentiment, and hospital managers are unwilling to go beyond this. Most of the hospitals have power to control patients a certain specified time, agreed upon when admitted to the hospital. But apart from the view tiiat special retreats are neces- sary for the sake of inebriate patients, I would urge their estabiisiiment in order to relieve the families of such 222 DISEASES OF INEBRIETY. patients of the burden of maintaining them. I know of many instances where tlie wife could provide for herself and children, but an attack of inebriety in the husband tlirows all back. He must be watched day and night while tlie attack lasts, medical attendance and medicines must be procured, the siiop or the sewing which would otherwise bring in enough to keep them is necessarily neglected, and slie is obliged again and again to appeal to friends, who begin to get weary of giving assistance. The poor wife says: " Something must be done; he must be put some- where ;" but the prospect of prison or of the lunatic asylum deters her from taking any action, and she says : "Well, I will give him another trial." Tiiese poor women have bitter lives, and many of them make noble sacrifices for the sake of their families. The State ought to afford them a ready means of relief from the consequences of a physical and mental disease in their husbands for which they are in no way responsible. I would then propose the establishment of hospitals for the care and cure of inebriates, such hospitals to be either supported by the State, or else under State inspection and control. That persons suffering from inebriate disease should, if the outbreak of the disease be recent, on the rep- resentation of their friends to a magistrate, and after due examination by medical men and proper certificates being signed by them, be committed to one of the hospitals for nervous diseases for a j'ear. That the period of detention in such hospital might be lessened on the recommendation of the medical ofiiceis. That during the patient's residence in such institution he should be obliged to do sufficient work to pay the expenses of his living, and the surplus to be lianded to iiis friends for his support on his discharge. The object of the work would not be merely to pay expenses, but to give healtiiy mental and bodily occupation ; to sub- stitute healthy nerve-work for unhealthy impulses, and thus to act curatively. In cases where such seclusion and abstin- ASYLUMS AND THEIR WORK. 223 ence from alcohol for a year had been tried without effect — that is, in cases of presumed incorrigible drink-mania — the patient should, on each outbreak, if not under proper care and control, be admitted for treatment until the attack should be over, and he should be detained as long as the medical officers thought fit with regard to his safety. I have explained what proper care and control means, but will do so again. It means such care as will prevent the patient getting alcohol during the attack — an exceed- ingly difficult measure to carry out in private houses. I would avoid the use of the word " asylum," and name an institution for the treatment of inebriates " Hospital for Disease of the Nervous System." It could easily by speci- fied in the rules of the hospital for which particular nervous disease it was intended. Such a name would be less repug- nant to the patient than the word " asylum," and would serve to educate public opinion. The establishment of such State hospitals might be objected to on the score of cost, but it must be evident that the community pays far more heavily by the present system, or want of system, than it would do if special hospitals were established. We should then be saved the expense of maintaining such patients in prison ; and such special hospitals could be made self-sup- porting to a very great extent, rendering the estates of those who were able to pay liable for their maintenance, while the others should work for their support. Inebriates who might be allowed to live out of the retreat on parole, could, if they broke their parole, be treated in the nearest public hospital and discharged when the fit was over ; but if they again broke out they could be committed to the retreat for the full time on the recommendation of the medical officers, without option of leaving until their time should have expired. Dr. Day, of Washingtonian Home, makes the following clear and positive statement of results. Twenty-two years of experience in this work has demonstrated that the task 224 DISEASES OF INEBRIETY. is neither hopeless nor thankless ; nor would it be if the measure of success had been lessened one-half from the known rate of percentage of cures. I know of no hospital, infirmary, or reformatory institution in the country — and I may as well say, in the world — in which the proportion of cures to the number of patients treated is greater than it has been annually in this Institution, from the date of its origin down to tiie present time. A variety of circumstances beyond our control prevents us from making a fair and just exhibit of our success to the world. A man will go to the hospital or infirmary with a disease or a broken limb, and when healed, or made whole, there is no hesitancy or delicacy on his part, or with his friends and relatives, in making the fact generally known ; sometimes, especialh'^ when the patient is of sufficient conse- quence, the community will acquire this information from the public prints. But it is different with the recovered ine- briate, who, for his own or family reasons, shrinks from a confession of his case, and while he rejoices, and is thankful and grateful for his cure, has a natural repugnance to ac- knowledge tliat he actually needed the treatment he received. Hence it is, that numbers of men are reformed at the " Home" who return to their families and to their busi- ness, giving joy to friends and neighbors, not one in ten of whom know how or where the sudden change was wrought. As a rule, failures occur with persons who are willing to be cured if it can be done without making any sacrifice or concession themselves towards effecting such a consumma- tion. However honest their desires may be to live soberly, they have not strength of will sufficient to resist strong and repeated temptation. Is not this the case with transgres- sors of every physical, moral, and Christian law ? . , . But even such cases are not without hope. Proper medical and dietary treatment may do much to build and strengthen their physical system, but what they need most is medicine for a diseased and weakened mind, and that is a ASYLTJMS AND THEIR WORK. 225 curative agent not to be found in a drug store or a physi- cian's medical case. In most cases a longer lapse of time is required to efTect a cure than the patient thinks he can spare from liis busi- ness, or afford to pay for. The deaf, the hime, the blind, and the sick, who satisfy themselves with one or two visits from tiie piiysician, when their several cases require a patient and lengthened treatment, have just the same right to declaim against the efficacy of medicine and surgery, as the public have to charge us with failure in cases where we liave been permitted to treat only for days, when we should have had weeks, and weeks when months were fairly re- quired. CHAPTER XXIII. HYGIENIC AND HOT AIR TREATMENT OF INEBRIETY. There are two classes of drunkards to be found in the United States — one class are drunkards because of their training and education ; the other class is born with a ten- dency to drunkenness. Let me call attention first to begot- ten drunkards. These are peculiar. At the time of their conception the father and mother were habituated either in their foods or drinks to the use of some form of stimulants ; not necessarily were these alcoholic or fluid in their nature. Stimulants are substances which contain in their constituent elements properties that when taken into the human stom- ach by eating or drinking have a specific effect on the nerv- ous system, exciting the heart to undue action, and through it the whole circulatory system, insomuch that the person thus affected takeS on an unnatural condition of the vital organs, by which he is subjected to extraordinary activity of such organs. This condition, continued long enough, becomes habit- ual, and under it no person can go into the procreative act without carrying over to the offspring a constitutional dia- thesis or habit of body, or, in other words, a tendency or predisposition to the use of stimulants. The child thus made up has in him a need for stimu- lation in order that the vital organs may perform their work to the best advantage, and there will be failure in their action unless this need be supplied. The child maj linger along, being feeble ; but, if his habits are such as are common to the children of our country, he will die unless help is given him through stimulation. A physician, if 227 228 DISEASES OF INEBRIETY. called to such a child, would almost surely discern the need of extrinsic aid being furnished, in order that the vital organs might perform their functions with sufficient direct- ness and vigor to result in good iiealth and continued life. Under such circumstances, how is a person to be kept from becoming a drunkard ? That is a problem which science and morality, separate and together, have been unable to solve hitherto, and will be unable so long as persons permit themselves, wliile under habitual stimula- tion, to beget and give birth to children. It is not at all necessary, in order that a child's organization shall have such idiosyncrasy as to call for and require stimulants, that either of the parents shall be drinkers of alcoholic liquors. It is enough that through food eaten or medicines taken, stimulants are constantly introduced into their circulation. Nature, in her great organic processes, knows nothing of, nor cares anything about, the particular substances a person uses whereby his whole system is extraordinarily excited. It answers all evil purpose that this excitement of the nerv- ous svstem is created and constantly kept up. A married pair can give birth to children in whom shall inhere a tendency to demand stimulation to that degree that a clamor for it is set up in the very center of their bodies, just as surely by the eating of stimulating food as by the drinking of stimulating drinks. Of begotten drunkards the numbers in this country are larger by far than are the numbers of trained and educated drunkards. There are but very few children now-a-days who have not in them a natural desire for stimulants. Denied these in every form, they put forth but feeble growth, and in many ways show inefficiency in the perform- ance of those bodily functions which must be fully and fairly exercised in order to the production of good health. Here, then, is an evil of great magnitude which is not touched at all by any temperance movement yet inaugurated, and herein lies the secret of the imperfect success of all HYGIENIC AND HOT AIR TREATMENT. 229 such movements. Little or nothing is gained as respects the arrest and overthrow of intemperance while the cliildren who come into the world have not only a natural liking for liquor, but have also what may be called a natural need for it. Every generation repeats the story of its predecessor. As the child grows up his liking for stimulants takes on the form of a need for them. When puberty is reached, the boy, whose activities are tlien drawn upon more largely and decidedly than at any previous period, finds that to answer to the simple nutrient wants of his system, so far as muscu- larity is concerned, does not meet his necessities. He may be in good muscle and so of good size of body, but there is a defect in him not to be overcome by force of will when he is called upon to show large, well-directed, and successful energy. He lacks just at this point the agency by which energy alone can be developed, and if he cannot have aid he fails. It is this cry in his body for stimulation, for something to innervate him and make him feel strong, that sets him to drinking ; and this clamor is just as likely to be manifested if his father and motlier are total abstainers from all intoxi- cating drinks as though they indulged habitually in them. Total abstainers from these drinks, who do not abstain from other stimulants, may use them to a degree and in a measure that will produce quite as deleterious effects on the nervous system as would be produced by drinking alcoholic bever- ages. So the cliild born of parents who are pledged to the entire disuse of intoxicating liquors, may have a natural desire or need for alcoholic stimulants, as truly as the child born of parents whose nervous systems have been habitually excited by alcohol. The object tlien to be sought must be, not the exchange of stimulants, but tlie abandonment of them altogether. Then cliildren will be brought to birth with no tendency in them to the use of stimulants, and then they can be trained up and reared along a line of sobriety and abstinence from 230 DISEASES OF INEBRIETY. all Stimulants, which will make it quite out of the question that they should ever use intoxicants in any form. There is a process by which a child with an inborn need for stimulants, in order to make his organs perform their natural functions, can be reconstitutionalized. That pro- cess involves freedom from taxation of tlie nervous system for years after his birth. The child lias to be cared for and looked after like a young animal. The developments that need to be made in him are such as affect tlie nutritive nervous system. He should be kept free from all cerebral excitement. He needs to be cared for by judicious and wise nurses. He cannot be permitted to eat or drink, nor do or be, as children usually are. If he were thus related to life he would die ; but if he can be kept free from all unnecessary excitement of brain and be handled with close watclifulness for the first three or four years of his life, his relations to vital development will become greatly changed, and from that point on, the reconstructive processes, so well begun, will proceed to com- pleteness. He will ultimately reach a condition of his nervous organization where he will no longer need stimula- tion. Till that is accomplished, attention must be given to him or, with no stimulants administered in his food or drink, he will fade away and die. It is most unfortunate that a child should be made up in a state of dependency upon factitious aids, but where such dependency exists, reconstructive meas- ures can be instituted and made effectual. This I have proved on tiiis Hillside to the satisfaction and joy ofagieat many parents. The better way, however, is to forestall such an issue as this, and not have children begotten when the parents are under a bodily habitude of subjection to stimu- lation. For a long time I have been convinced that the present temperance reformation is radically inefificient. Theunphilo- sophical aspect of it will have to give way before a broader HYGIENIC AND HOT AIR TREATMENT. 231 and more effective effort, or we shall liave to keep it up for- ever, having in each succeeding generation as many or more persons becoming drunkards as in generations preceding. The second class of drunkards — those who are made so by education and training — are persons not born with a constitutional necessity for the use of stimulants. As chil- dren they do not in our country constitute a very large class. They never need be drunkards. Tiie temptation to drink is not in their bodily constitution. It lies in society in some or other of its forms of associations. Thrown into good and upright relations from childhood, they will not become drunkards. They will not even drink liquors moderately. As they develop into intelligence and moral sense, they will see that the use of stimulants for purposes of exiiilaration, or of innervation of the nervous system, is not good for them. They will be ready to join the total abstinence ranks, and when they have joined them, they will stand true. But out of this class there is a certain number who do become drunkards. These lack the early training and right association and proper surroundings. They eat highly stimulated foods and drink stimulo-narcotic drinks, like tea and coffee, until they have created in them an abnormal desire for things that are exciting. No person can habitu- ally eat largely of the indiscriminate foods used in most families, and drink such beverages as are there daily imbibed, without after awhile coming to have a longing for stimulation. Young persons come to have a want for some- thing stronger than tea or coffee, and many of them have opportunity at the home table to indulge in the milder forms of alcoholic drinks. So they go on from bad to worse and from worse to worst. Out of this class a certain proportion become drunkards and once they are habitually inebriated, their restoration to permanent sobriety is as dif- ficult as though they belonged to the first class. This cure does not lie with certainty in any movement 232 DISEASES OF INEBRIETY. which simply makes its appeal to the moral sense. A drunkard may be said to have no moral sense. He has a physical sense and he has a social sense. His physical sense tends directly to keep him a drunkard. His social sense may work for his recovery. He may be so situated that social influences shall operate to induce him to sign a pledge that he will not drink any more, and here and there may be found one out of a great many who will keep such a pledge, not by reason of any inherent strength which he himself has whereby to keep it, but by reason of the outside influences which affect him and the watch-care which is had over him. If thinking men and women will take pains to investigate this matter as thoroughly as I have done, they will see that a very large proporiion of the whole number of drunkards in this country is made out of the class which is born with a liking for, with a tendency to, and with a need of, the use of stimulants. It is now coming to be recognized that inebriety is a disease, but its treatment has heretofore been too much relegated to the moralist instead of the physician to whom it properly belongs. The moralist has given us theories as to its cause and cure, but the theories have brought us no advancement ; the disease still remains to vex their patient souls. The medical profession, however, place this subject in its true ligiit, and give aliope to the world that in a short time there will be a better way to handle this whole matter. Dr. Wright most forcibly says : "Drunkenness is in every essential particular a condition of civil death, and it would seem best that it should be so construed by the law of the land." Society should be protected from the habitual drunkard, and especially should he be protected from him- self. To my mind the bane of the age is excessive alimen- tation, leading up to a desire for stimulants, which is ' naught but a morbid craving, and in ignorant hands stim- ulation is supposed to ward off its consequences. On the contrary, and in reality, the use of stimulants at HYGIENIC AND HOT AIR TREATMENT. 233 such times induces a condition of internal inflammation that increases the desire for further stimulation, and also the inability to properly dispose of whatever aliment may be present, thus effectually rendering a bad matter worse. We well know that nothing will so speedily subdue the nervous storm as the ever convenient and alluring alcohol. It is sought to give insensibility to nerve agony, and secures for a time, rest and repose, but the wear and tear of this oft repeated nerve strain is frequently shown in paralysis and sometimes insanity. Perliaps the most serious effect of alcohol is its direct tendency to interfere with nutrition, and by promoting growth of cellular tissue to compromise the integrity of the brain tissue where the poison is not readily thrown off, and where it soon destroys not only its co-ordinating power, but degenerates the brain substance. Inasmuch as the mental and moral character of the individ- ual depends upon the action of the brain itself, we cannot look for good results when there is any impairment of its substance ; on the contrary, we often see the worst results from such a condition. The impairment of consciousness is only one of the many forms by which the influence of alcohol is felt, and suggests the question whether we have any process whereby its elimination may be successfully secured. We also know that with tlie inebriate thei-e is a lack of fine moral sense, not infrequently amounting to obtuseness, and that this condition is far reaching, affecting even the progeny, thus making it hereditary. If there is a process whereby the blood itself can be purified, we may, witli every reason, expect tlie brain tissues to participate in the advantages derived tlierefrom, and consequently we will have greater clearness of perception, followed by a quickened moral sense. The irresistible impulse of our modern civilization, from infancy to old age, is push, and the mental and physical powers alike suffer in tlie long run. The free use of alcohol is accountable for a large measure of this condition. Can 234 DISEASES OF INEBRIETY". we not teach the people to give more time to rest and recuperation and less to stimulation ? If it is wished to place tiie inebriate in the condition most favorable for cure, it is important that there should be institutions created for that purpose. Granting that inebriety is a disease, our efforts should be to eradicate that disease, and in order to do so, there must necessarily be desirable sunoundings as well as con- trol over the patient. The model institution is yet to be built, wherein the hot-air bath shall hold a pre-eminent po- sition, where narcotics shall be entirely disallowed, even though it may be an improvement on inebriism to have one's system saturated and senses blinded by narcotism, and when there shall be enough control to prevent any dallying with the tempters. The theory of the action of the hot-air bath is very simple. Like the action of the sun's rays upon Bunker Flill Monument when shining upon one side and causing it to lean toward the other, so does this agent act gently and yet powerfully. The primary action of heat, which is the one essential thing of the Turkish bath, is to relax the tissues of the body and thus invite a more perfect circulation to every part of the system ; by a more active circulation every sense is quickened — the secretions are more thorough, the excretions more perfect, the blood is better supplied with oxygen — the skin assumes its natural roseate complexion, indicative of the improved condition, and each and every function, whether it be that of the lungs liver, spleen, or bowels, comes in for its share of the general benefit — in a word, it opens every pore of the skin, and hence, the most perfect sewage to the body The secondary action is tiiat of profuse sweating — where water from the blood and debris or used-up tissue and poison held in solution are rapidly thrown out of the body. According to recorded observation, "the quantity of blood in the body is lessened by tlie free excretion which takes place through the skin and lungs ; the body weight is HYGIENIC AND HOT AIR TREATMENT. 235 reduced, and the work of tlie heart in this way liglitened, at tlie same time that its substance is better nourislied by the improved quality of tlie blood supplied to it. The peripheral arterioles of the body, too, become dilated and filled with blood, thus affecting a corresponding emptying of the blood vessels of the internal organs. Lastly, as a result of the alternate warm and cold douching, the vaso motor energy of the vessels is increased, thus rendering them more capable of resisting any strain thrown upon them." Thus it will readily be seen how quickl}'^ congestion, wherever it may be located, is broken up and the offending material thrown out through the pores of the skin. Under such conditions absorption and elimination have their most perfect oppor- tunity and equalization crowns the work. It must be apparent that alcohol is soon eradicated from the system under such favorable conditions, and that torpidity gives place to activity. Furthermore, no living tissue or vitality can be abstracted by the process — nothing is thrown off but what the system is better without. One bath has been fre- quently known to relieve an intermittent pulse, giving a smooth, regular action to the heart, indicating a well bal- anced circulation. What known drug can do this in the space of half an iiour? And another great advantage in favor of this treatment is, that there is no poison left in the system to work its way out, as is sometimes the case when drugs are administered; per contra, the individual is left in a calm and quiet frame of body, which necessarily reacts upon the mind. It could not be maintained that the hot- air bath would renew brain or other tissue where there has been actual lesion, but it will place under most favorable condition for repair what is left, and then adjacent or collat- eral parts will do their best to carry on the work of the injured part. By placing the patient in an institution of the kind men- tioned, we at once completely remove the cause of the disease, and then with the bath we have only the effects to 236 DISEASES OF INEBRIETY. treat. In the instance of insanity the hot-air batli has in a large number of cases brought relief to deranged conditions and given harmony to disturbed mental functions, and this where tiie cause was present, for we know that this disease obliterates the patient intellectually, and leaves the physi- cian in the dark in reference to the cause or the effect of the malady. It must, therefore, be evident to every medi- cal mind, that the remedy which will effect every organ and create in it an action to throw off diseased conditions, is the only one to meet sucii cases. With how much more reason must we expect even better results in cases of inebriety, where the cause of the disease is eliminated and the advan- tages of treatment are more perfect. The mucous surfaces of the inebriate, and, in a minor degree, tliose of the mod- erate drinker, are in a chronic state of inflammation. The effect of the hot-air treatment is to reduce that inflamma- tion by purifying the blood, thereby relieving that immod- erate craving for stimulants, tliat only perpetuates and increases the disease instead of giving relief. During my long experience in the administration of the Turkish bath, many persons who had been more or less under the influ- ence of alcohol, have expressed to me in most unqualified terms the benefits that they had derived from its use, par- ticularly those who came after a debaucli. In fact, this has been thoroughly demonstrated, as tiie experience of all bath establishments will testify. Place man or boy in a clean suit of clothes throughout, and he will not only take good care of the clothes, but also of himself, and behave more discreetly than before. In like manner, if you thoroughly purify a man, as is done by one of these baths, he at once realizes that he is a cleaner man and on a higher plane, his senses are more acute, he is in his best condition, he respects himself so much the more, and is less liable to return to his base practices. It is stated as a fact that in no country has inebriety been found co-existent with the bath. Temperance and clean- HYGIENIC AND HOT AIE TREATMENT. 237 Hness are its handmaids. This treatment lias had but a limited trial in this countr\% though it has been successfully- used in a multitude of cases in Great Britain, particularly at Dr. Barter's establishment, near Cork, in Ireland. The only demonstration in this country was at Binghaniton, during tlie first three years of it administration, in which time not a death occurred among the patients. Dr. Lees, says: "In the case of persons having latent cravings for drink, we know of few things more efificacious than a short course of that peculiar method of cleansing, which, bor- rowed from the Orientals, has been recently introduced into many cities — we mean the Turkish bath. Who, suffer- ing from morbid accumulations incident to town life, that has ever tried these processes, has not felt a wonderful increase in the vital elasticity of his frame ! It is as though a heavy weight had been lifted from the bent spring of life, permitting fuller and freer play to the vital machinery and creating a feeling of sympathetic purity in the soul." The true physician stands before the community in the light of a teacher as well as a healer, and his opportunities for usefulness are large and often far reaching. Probably no class do more charitable work than the men of this pro- fession. In no way can they do more good than in encour- aging both by example and precept, those institutions that have for their object the welfare of the community, and no institution of modern times promises so much to the mass of the people as the genuine hot-air bath. Sanitary science is of incalculable value to each and every one of the com- munity, for it deals with that which is vital to the well- being of the whole, but the hot-air bath is sanitary science, refined and brought to the individual ; indeed it is the per- fection of sanitary science. As a prophylactic, it stands at the head of all remedies. As a disinfectant, none with it can compare. The more it is popularized, the nearer it will come within the reach of everybody, and the more widespread, necessarily, will be its blessings. CHAPTER XXIV. DUTY OF THE STATE IN THE CARE AND TREATMENT OF INEBRIATES. The State assumes the right to license reputable men to seii alcoliolic liquors to those who are in tiie habit of using them, to those who would like to experience their effects, and to those who wish to treat their friends to sometliing uncommonly good. This the State does in accord with tlie laws made to suit public opinion. If tliis " opinion of the public" would demand it, the State could very properly assume the right to license opium dens, or saloons of euthanasia, wiiere a fellow could shuffle off this mortal coil according to the most approved methods. In other words, public opinion forms laws, whether just or unjust, and it is the duty of all good citizens to acquiesce in a state of affairs brought about b}'^ the decision of the majority. In a study of this topic I enquire, Firsts Has a man the right to become a drunkard, and after he is a drunkard has he the right to be one ? The laws of the State permit the drunkard to be made, because tlie State licenses reputable men to sell alcoliolic liquors ; and the laws of the State concede the right to be- come a drunkard to every citizen, because the State says that personal liberty sliould not be interfered with. On the other hand, tlie laws of the State direct tiiat the drunkard be fined and imprisoned for being what his personal liberty entitles him to be. It is, therefore, logical to say, tiiat 239 2J:0 DISEASES OF INEBRIETY. according to the laws of the State, a man has a perfect right to become a drunkard, but that after lie is a drunkard he has no right at all to be one. Science claims that the inebriate does not exercise his free will to remain or to be a drunkard, for the simple reason that he no longer has a free will to exercise, but that lie is the involuntary slave of an uncontrollable desire. Science also claims that the drunkard may have never exer- cised his free will in the matter. He may not be a drunk- ard from choice, but he may have inlierited a predisposition to become a drunkard, and necessity, opportunity, and circumstances may have made him what he is, an habitual drunkard. Science further claims that it has demonstrated that ine- briety is a disease ; that the State licenses the making of this disease, and that the State does not judiciously recog- nize inebriety as a disease. Science further claims that no man has a right to become a drunkard, because, as a rule, every man has a choice in the matter, and he ought to choose what is best for the individual and for society. Science further claims that " Punishment is no cure for the Disease of Inebriety." The State and science, therefore, differ in their ideas about "becoming" and "being "a drunkard. The State considers "becoming a drunkard" a personal riglit, and " being a drunkard " a crime. Science holds " becoming a drunkard " to be a sin, and "being a drunkard " a disease. Second. Is drunkenness a disease? The laws of the State sanction moderate and temperate drinking. The men who made the laws did it in accord with the wish of the public. And the public, no doubt, is satisfied tliat the State cannot legislate its people into tem- perate habits. The people must be educated to be temper- ate through the press, the pulpit, the school, and the lecture. DUTY OF THE STATE. 241 There are men who are said to get drunk by accident. These are indiscreet and sliould not be judged harslily. They ouglit to beware of accidents lest they become habitual drunkards. Tlie habitual drunkard, however, suffers from a disease called dipsomania. Habitual drunkenness or dipsomania maybe inherited or it may be acquired. "Dipsomania is a mental alienation due to a morbid con- dition of the nervous structures, generally hereditary. The strictly periodical form of this type of dipsomania, the ten- dency to gradually shorten the intervals as the years pass, and the peculiar mental condition preceding the debauch, are a proof that dipsomania is a disease of the cerebral ner- vous centers analogous to recurring neurosis, such as epi- lepsy, etc. This disease is nothing but an attack of uncontrollable drunkenness, always kept up until the stomach refuses longer to tolerate the alcoholic drinks. Then the attack stops as suddenly as it came, the sufferer recovers his usual health and spirits and enters into his business in a way as if nothing had happened. As a general thing these attacks recur at intervals of from one to six months, and the end is, some disease of the renal, hepatic, or gastric organ carries off the patient. Earnest resolutions or pledges do no good to ward off the attack. When the time comes the patient succumbs. An indescribable feeling of weakness of the nervous system is generally the first sign of an attack. This may be brought on by over-work, over-study, anxiety, worry, trouble, anger, etc., and the patient thinking himself proof against a debauch by his long interval of sobriety, yields to the temp- tation, and then nothing can head him off. Friends, family, duty, rank, morality, resolution, and pledge are all forgotten, and the patient will drink as long as his stomach will bear it. So strong is this desire for drink, while the 242 DISEASES OF INEBRIETY. attacks last, that the patient will drink as long as he has money, or rather as long as he can get the liquor, though he may have to beg, borrow, or steal it. Such people are the despair of their friends, the tor- ment or ruin of their families, the scandal of their com- munity. Seventy times seven they fall and are lovingly raised up. They express contrition, they make firm prom- ises of amendment, but they always fall. From the researches of many authors it appears that inebriety is a nervous disease closely allied to insanity, which manifests itself either periodically or constantly. It may commence suddenly as a consequence of some severe shock to the brain. The disease may also have its origin in the social habits of the patient, who from a simple con- vivial drunkard may become transformed into a regular inebriate. It may be produced by the action of other poisons besides alcohol, so that there may be as many varieties of inebriety as of narcotics. There must, how- ever, be a predisposition to inebriety in order to effect its evolution. Healthy men without neurotic predispositions may drink voluntarily in moderation without thus breaking down ; but an inter-current disease may turn the tide even against such individuals, and if they do not themselves suffer the penalty of indulgence, their children will be found far on the road that leads to inebriety. Hereditary influ- ences are among the most potent that determine this dis- ease and they follow the usual course. Thus, in mixed families, the male children of an inebriate mother, or the female children of an inebriate father, may alone exhibit the morbid tendency. There is another type of drunkenness which goes under the name of ebriosity, and by which is understood the con- dition of continual half-way intoxication. This, necessarily, occurs only among saloon-keepers and those engaged in the liquor traffic, having access at all times to alcholic drinks. This is a very fatal form of drunkenness, and may be called DTTTT OF THE STATE. 243 incurable. It is the form of drinking which life insurance companies especially fear. Habitual drunkenness is, therefore, a disease brought on by the excessive use of alcoholic drinks, though this use may or may not have been continual, and the victim is an involuntary slave of an insane propensity. He knows what is right, but cannot choose it ; and he knows what is wrong, but cannot shun it. There is no loss of the power to judge of right and wrong nor any disturbance as to facts, but the mind is powerless to control conduct according to knowl- edge. This state which the drunkard is in may be called criminal irresponsibility. Third. Can the drunkard cure himself or be cured under the existing circumstances ? In the early stages of dipsomania, inherited or acquired, something can be done for the patient, but the cures are the exception. As to chronic cases of drunkenness a reformation is improbable and very nearly impossible under the existing circumstances. The temptations are too great and the opportunities are too many, and though the drunkard may have a desire to reform or to cure himself, his will-power is enfeebled and he cannot resist the demands of his habits unless he be removed from temptation and it be made absolutely impossible for him to get a drink. The drunk- ard is an object of contempt and disgust as a drunkard, and an object of pity and danger as a man, as a father, as a son, and as a brother. He is pitied by all good men, but they are powerless to help him. He cannot help himself. He cannot reform while he is in the midst of tempta- tion. The licensed liquor houses are easy of access, and indiscreet friends are not wanting to tempt him to go into such places and to take but one drink, which is the spark that lights the attack. Dr. Kerr says, " The struggle of the intemperate for free- 244 DISEASES OF INEBRIETY. dom is a combat more terrible tlian any other figlit on earth." It is a hopeless figlit, I add, if unassisted. Dr. Parrish sa3^s, "The temptation with which they are tempted is within. It is subjective. It circles in the stream that gives them life. It may be likened to a battery that is hidden somewhere in the cerebral substance — connected by continuous fiery wires, with a coil in every ganglion, from whence they continue to extend — attenuating and distribu- ting as they go, reaching after the minutest nerve fibrils, which need only a throb from the inborn impulse to trans- mit a force that quivers in every muscle and burns in every nerve till the victim is suddenly driven to debauchery." Tell me now, is not the condition of the drunkard a deplorable one ? In fact, is it not a blot on civilization ? Should not something be done to prevent the increase of drunkenness and to diminish what there is of it.-* Fourth. If the drunkard cannot cure himself, has he a right to be protected against himself and against those who are licensed by the State to sell him the wherewithal to remain a drunkard ? It is true that there are a great many private institutions throughout the country for the cure of inebriates, and they do a great deal of good, but the charges for treatment in these institutions cannot be met by the majority of drunk- ards. Taking into consideration that less than a year's treatment will do no good, it is quite plain that the majority of these unfortunates have, under tlie circumstances, no chance whatever offered to them to become cured of their malady. This is a serious matter to those afiflicted with the drinking habit, and it is in their behalf that I make this appeal to the citizens of Indiana, relying on their feelings of justice, charity, mercy, and humanity that my efforts in behalf of the habitual drunkard will not be without success, I ask for these unfortunates nothing but what is just. There is no hope for these poor creatures until they are withdrawn from temptation and placed under restraint. DUTY OF THE STATE. 245 Fifth. After a man becomes a drunkard is he a danger- ous man to society ? and, if so, has society a right to be protected against the drunkard ? The State protects society against the drunkard in the following manner : 1. The law assumes that he who, while sane, puts himself voluntarily into a condition in which he knows he cannot control his actions, must take the consequence of his acts, and that his intentions may be inferred. 2. That he who tlius voluntarily places himself in such a position, and is sufficiently sane to conceive the perpetra- tion of the crime, must be assumed to have contemplated its perpetration. 3. That as malice in most cases must be shown or established to complete the evidence of crime, it may be inferred from the nature of the act, how done, the provoca- tion or its absence, and all the circumstances of the case. 4. The law has not yet judicially recognized inebriety as a disease. The State does in every way trj' to prevent the making of robbers, thieves, burghirs, and murderers, and criminals in general, but it licenses men to make the drunkard. The State protects society against the murderer and the robber by imprisoning him, but it allows the drunkard to con- stantly menace the well-being of society. Would you say that the poor wife, who supports herself and her children by sewing and washing, has no right to be protected against the evil habits of her husband ? Would you siy that tlie drunkard's children have no right to be protected against the evil influence, the bad example, and the burden of drunkenness of their father, which threatens to blight their whole lives ? Would you say tliat the friends of the drunkard have no right to have an asylum provided, wherein they may place their unfortunate son or brother or sister or father or mother or friend, in order that they may 246 DISEASES OF INEBRIETY. be cured of their malad3% which is a curse to ail coming in daily contact with tiie habitual drunkard ? These are questions that can have but one answer. Yes ; society should be protected against the drunkard, who is made by consent of the State in accord with public opinion. Sixth. If society has a riglit to be protected against the drunkard, if the drunkard has a right to be protected against himself, and if the drunkard has a riglit to be protected against those who are licensed by the State to sell him the wherewithal to remain a drunkard, does it not follow that the State should afford the protection ? In answer to this question I read you several extracts : " From the very nature of the malady it is scarcely to be expected that the inveterate drunkard will voluntarily sub- mit to control, or continue under it for a sufficient length of time to receive lasting benefit ; and therefore it seems essential, as in the case of other insanities, that legal power, with, indeed, the neglect of law^ to provide such a check and remedy, seems inconsistent, unjust, and inhumane when we consider that while it permits the insensate drunkard to endanger his life, to waste his property, and deprive liis family of that which they are justly entitled to expect from his hands during life, or to fall to them at his death, it holds him responsible for any criminal act he may commit. No doubt the law assumes that he drinks voluntarily, and with his eyes open to all the consequences, and that his practices therefore form an aggravation of his guilt ; but such is not the case, for he drinks involuntarily, and he is unable to exercise his reason aright or govern his will." " All experience has shown that little progress or none can be made toward the permanent recovery of a dipso- maniac so long as his business places him in more or less contact with alcoholic drinks, or in frequent association with drinking comrades. Consequently, both physician and friends should combine their influence to separate as far as possible the patient from such associations. And if DUTY OF THE STATE. 247 it cannot be done in any other way, let him be induced to take a residence for six or twelve months in a well-regu- lated asylum for inebriates until the paroxysmal tendencies have been broken. Enforced seclusion in a proper asylum, with no possibility of obtaining any kind of alcoholic drink, but where good air, good food, kind treatment, and some suitable employment can be furnished, on the same prin- ciple that applies to the treatment of insane persons, will save them from early destruction." "For the permament cure of inebriety, however, nothing avails but special treatment in hospitals provided for this class of patients. Of these the number is increasing as the public becomes informed regarding the nature of the dis- ease and the appropriate means of combating its ravages." Dr. Carpenter says : " However responsible he may have been for bringing the disease on himself, his responsibility ceases as soon as he comes under the influence of the malady. The disease, however, may not be brought on by the act of the individual, and then it is clear at once that neither directly nor indirectly can he be deemed responsible. But, suppose that it were the result of his previous conduct, I repeat that, however culpable he may have been for that, he is not a responsible being while afflicted with the malady ; for I can see no distinction between this form of the disease and any other which has been induced by the habits or acts of the individual. " The only chance of a cure or alleviation is from atten- tion to the health and abstinence from intoxicating liquors. Neither can he be cured so long as the patient is at large, and no amendment can be depended on, unless he has undergone a long course of discipline and probation. Con- sidering, then, that the individual is irresponsible and dangerous to himself and others, and that his disease can be treated only in an asylum, it is not only merciful to him and to liis relatives, but necessary for the security of the public, that he be deprived of the liberty which he abuses 248 DISEASES OF INEBRIETY. and perverts, and that he should be prevented from com- mitting crimes instead of being punished — or, I should rather say, being the object of vindictive infliction — after he has perpetrated them. " Of the chronic form I have seen only one case com- pletely cured, and that after a seclusion of two years' dura- tion. In general, it is not cured. Paradoxical though the statement may appear to be, such individuals are sane only when confined in an asylum." The insane asylums cannot and ouglit not to be used as a home for inebriates. Only those in the last stages of alco- holism, that is, only those who are actually insane, are sent there. Special attention cannot be paid to cases of inebriety in the insane asylums ; besides, no one would voluntarily apply for admission into an insane asylum, and if he were to do so, it were questionable whether he would be admitted. Therefore, the insane asylums offer no aid to the inebriate. Seventh. If the State should afford the drunkard a chance to be cured of his malady, how can it be done ? The only way in which the State, under the existing cir- cumstances, can provide a protection for the drunkard, so that he may be cured of his malady, is by erecting and maintaining homes for inebriates. The sending of confirmed drunkards to these homes should be made compulsory by laws in the same manner as the insane are sent to the asylums. Voluntary entering into the homes by confirmed drunkards should be encouraged, but only allowed after a proper examination by two physicians, who should certify as to the condition of tlie patient. A complete history of the case would also help the medical superintendent and his medical assistants in treating the patient. The inebriate must remain at the home at least a year, when the medical superintendent, under the advisement of the board of trustees, may let the patient out on trial until he has proven himself able to govern his will. The friends should not be allowed any control over the patient after he DUTY OF THE STATE. 249 becomes an inmate of the home to which, according to cir- cumstances, lie is assigned. It is not my object to direct just how these homes should be built and afterwards carried on ; all this is subject to the decision of those who make the laws ; but I feel that in order to make this paper of sufificient worth to merit attention, I must give a general outline of what can be done for the inebriate. With this object in view, I will suggest that the money derived from the licenses issued and from the fines collected from those who are not yet confirmed drunkards, and from those who transgress the law by selling to minors, by selling on Sundays, by selling without a license, etc., be used for erecting a home for inebriates of the male sex, and another for the female sex, and for the sustainment of these homes. The homes, after they were once in good working order, could be made self-sustaining under efficient management. Indeed, the inmates should be employed in labor, in order to learn discipline and improve their bodily health. They should also be afforded recreation and amusement to pre- vent discontentment with the situation in which the}' are placed, and to convince them that there are other ways of enjoying life besides sitting in a saloon and becoming drunk. These homes should be erected in the country, away from temptation. Proper rules and regulations should gov- ern the inmates as well as those in attendance. The super- intendents should be medical men, who ouglit to be under the control and advisement of a board of directors or trus- tees, one of whom should be the President of the State Board of Health. The salaries of the officers should be regulated by law, and they ouglit to give a bond. Politics would necessarily have something to do with tlie appointing of these men, which, undoubtedly, would be for the best. The drunkard who is out on trial should be considered as belonging to the institution until he has kept sober for 250 DISEASES OF INEBRIETY. the time of one year. Should he show signs of return of his malady before the year is up, he should immediately be brought back to the home. It is presumed that the person who can keep sober one year is no longer to be considered an habitual drunkard. CHAPTER XXV. CARE AND CONTROL OF PAUPER INEBRIATES IN TOWNS AND CITIES. A certain proportion of the population of towns and cities are composed of what are called the " Criminal Classes " — those that require the constant espionage of the police, and the adjudication of justice. Intermingled with these in no small proportion is tlie pauper inebriate — friendless, home- less, — appearing in varions roles on the public stage as drunkard, tramp, or vagrant, many times entered on the blot- ter of the police station as an " habitual drunkard," or "rounder," — appearing at the various hospitals and dispen- saries with disease or injury incident to his habits — finally we find him in the wards of the charity hospital or among the chronic insane of the insane asylum, if perchance sudden death from natural causes or suicide has not intervened — and whether his career terminates on the street or in the hospital, or the cell or asylum, the trench in " Potter's Field " receives him, and thus the story ends. During the year 1887 the department of police and excise of the city of Brooklyn report 23,912 arrests ; of these arrests 13,862 were for intoxication ; of these, 108 are stated as habitual — we presume this to mean that they were known to the police as "habitual "drunkards, but it will at once be seen that this is entirely out of proportion to the number arrested. It would be no risk to say that of the 13,754 intoxicated persons arrested, many, if not the larger proportion, were habitual or periodical users of alcoholic stimulants, and that to intoxication. 251 252 DISEASES OF INEBRIETY. The English testimony as to the relation which alcohol bears to the so-called criminal classes is very conclusive. In the "testimony of chief constables and superintendents of police," taken before " The Committee on Intemperance for the Convocation of York," in 1874, in reply to this ques- tion — " What proportion of those who have come under your cognizance as criminals have been the victims of drinking habits and associates." A. " If by the term criminal is meant persons convicted of any offence against the law, sixty-five or seventy per cent." B. " Nearly all." C. " Fully nine-tenths." D. " Quite nine-tenths." E. "Twenty per cent, of the summary convictions of one year are absolutely for drunkenness — exclusive of a large proportion of the residue attributable to drunkenness." F. " Nearly half the entries," G. "About three-fourths." H. " During the past twelve months in this division there has been 283 persons apprehended for serious offences. I can safely state that 200 apprehensions were directly caused from the effects of drink." Question — " What proportion of those taken into custody are under influence of liquor ?" A. " 25 per cent, in country, 70 per cent, in town." B. "Those directly arrested and those summoned, all cases, 90 per cent." C. " 70 out of every 100 persons when arrested are drunk." D. " 161 persons arrested in this district in one year, 75 were under influence of liquor." E. "50 per cent, are apprehended as drunks and disor- derly independent of any other offence." F. " The majority of persons arrested and charged with drunkenness. I should say 70 out of every 100." We then have the testimony of chief constables, superin- CAEE AND CONTROL IN TOWNS AND CITIES. 253 tendents of police, governors of goals, and chaplains, that at least two-thirds if not three-fourths of all arrests made by the police, the persons were addicted to the use of alcohol, and that a large proportion of these were intoxicated when arrested. If we were to consult the police and criminal records of any of our large cities, New York, Philadelphia, or Boston, we might not equal but we should certainly approximate such testimony as that given before the " Convocation at York," We cannot then shut our eyes to the fact that in every city and town a certain proportion of the population are more or less continually under the influence of alcohol, and that to a degree often dangerous to the community at large. Intoxication, with or without overt criminal acts, continually occurs, rendering it necessary to arrest and imprison this class. The question now before us is whether the present method of dealing with the inebriate is the best, and if not, what are its disadvantages. Those who have given thought to the subject confidently assert, that the present method of arrests, fines, and short term imprisonment (or occasional six months) is not the proper and scientific way of dealing with the inebriate. By this method, on regaining his liberty the individual simply repeats his act of intoxication and is again subject to arrest, fine, or imprisonment ; after this has been repeated several times, he is known as the " repeater," or " rounder." Instances are on record where one person was subjected to arrest for intoxication over one hundred times, a period, of course, extending over some years, A female is reported as having been convicted forty- eigiit times for various offences, at all times committed through drink. She paid ^200, or $1,000, as fines for drunk- enness. The large majority in English prisons of re-com- mittals are due to intemperance. If crime be associated with the intoxication, as assault, grand larceny, tlien the 254 DISEASES OF INEBRIETY. clironic inebriate, strange to assert, will get the best treat- ment ; tlie law will give him the full benefit of his criminal act. Restraint, and a long continued period of total abstin- ence will be enforced during his term of imprisonment, and when his sentence expires, he will often leave greatly benefited, and practically a sober man. Instances aie on record where the inebriate has requested that he might be placed in prison and thus secure restraint, seclusion, and the discipline of prison-life, and thus attain habits of sobri- ety. The testimony from English prisons is singularly unan- imous on this point as well as conclusive. Question — " Do you consider the health of patients would be affected by total abstinence from intoxicating drink ?" Governors of jails testified " prisoners are universally bene- fitted ; there are cases where it might be occasionally used, as in feeble and broken-down prisoners — but these occasions were rare." As a rule, men who have served long periods of imprisonment, and who have been habitual drinkers, go out heavier and better in health than they came in. Their general improvement in health is due to cleanly habits, warm bath, good ventilation, regular rest, systematic exer- cise, connected with prison discipline, and total abstinence from liquor of all kinds. This result incidently points out clearly, we think, the general plan and method by which we ought to control and treat the pauper inebriate. He ought to have all the advantages that prison discipline may secure to him with- out the necessity of a criminal proceeding on his part. Undoubtedly, the law, in dealing with the inebriate, simply as an inebriate, is faulty or only partial in its effect upon him. "It practically does this, it arrests him, and fines or imprisons him for a short period — too short for any benefit to be derived from it," — and then lets him go. The law is like an incompetent physician : it first makes a wrong diagnosis, and then prescribes an inert and therefore inef- CAKE AND CONTROL IN TOWNS AND CITIES. 255 fectual remedy. It reprimands the inebriate, it does not treat his case at all. It looks upon the inebriate as an indi- vidual who has the knowledge of right and wrong, and full power of volition ; it regards the act of inebriation as deliberate and voluntary, and therefore it proceeds by fines and imprisonment to lash back into moral decency and rectitude the offender. But do we not recognize the value of restraint ? Would we permit the brawling drunkard to make night hideous, or the insane drunkard to scatter ruin right and left ? Cer- tainly not. What plan would then have all the advantages of the present system of dealing with the inebriate, and none of its disadvantages ? In the first place, as to arrest and restrahtt. The inebri- ate should be arrested if found intoxicated upon the street or any public place, or upon a warrant issued on due complaint of his family, or in case they failed to do their duty, by a committee of reputable citizens of the ward in which the inebriate was a resident, or the officers of said ward. A warrant should be issued on complaint from any of said parties, by the proper justice, and the inebriate arrested. Proper testimony sliould then be secured as to facts concerning his inebriety from reputable medical and other sources. He should then be sent to an inebriate reformatory, hospital, or work-house, for the institution should include all these features ; we are dealing with a diseased person, not a criminal, but as a pauper inebriate, without friends, or if he has friends, without means. There are abundant provisions for the wealthy inebriate. Private asylums are numerous, and the appointments are very complete for his treatment both here and abroad. It is the pauper, his more unfortunate brother, whom we are considering. The pauper inebriate is now duly arrested ; he must be restrained and controlled for some definite time in some 256 DISEASES OF INEBRIETY. institution. The period should be not less than one year, made longer if necessary by recommittal. The institution to which he is committed should be placed in the suburbs of the city or town, with convenient access to it. Abundant grounds should surround the building, or, better still, a farm should be the site of its location. Out-door occupa- tion, so beneficial in the treatment of the chronic insane, would be no less so in the case of the inebriate. A compe- tent medical superintendent, with suitable assistants, could readily conduct such an institution. Its inmates would be chronic inebriates ; all insane persons, or those incurable from other diseases, should be sent to their proper asylums or hospitals. Such an institution, with properly appointed work-shops, a farm under cultivation, well-stocked and planted, with a practical farmer at the head to regulate the labor of the inmates, would be almost self-sustaining, for the inmates would not be like those in an insane asylum, mentally inefificient, or those in a charity hospital, physi- cally helpless, but many would be skilled workmen who outside would command good wages. Then, also, a system of payment for extra work might be made, so that when they left the reformatory something would be due them, and they would not be turned out paupers. If this plan were adopted, a large body of chronic inebriates that now drift about in the community would not only be restrained but made to a certain extent self-supporting, and in a cer- tain proportion of cases cured. The inebriate Home at Fort Hamilton is based on some such plan, and demonstrates on a moderate scale what might be accomplished on a larger one. Every large town and city should have such an institu- tion of sufficient size to meet its wants, containing a farm, a work-house, and suitable medical care. It should be readily accessible, although the price of land would regulate somewhat the site of its location. The locality should be healthy, and the internal and sur- CARE AND CONTROL IN TOWNS AND CITIES. 257 rounding sanitary conditions good. The dietary should be generous, of good quality, and the food well-cooked. This is essential. Specialists in lunacy have found that a certain way to precipitate acute or sub-acute lunacy into the ciironic forms is to put the patient on low and innuiritious diet. Out-door exercise and occupation, as well as those measures that will eventually appeal to his better nature, lead him back to thoughts of home and family, develop his higher tendencies, prompt his aspirations, and raise him above the mere animal life he has led so long. To deprive such a one of religious privileges, or the intellectual enjoyment he may crave, is a refined species of cruelty that no true form of philanthropy would be guilty of or tolerate. This is no sentiment, it is practical fact and truth, for among these pauper inebriates are found lawyers, editors, physicians, clergymen, writers, artists, and skilled artizans, men who have fallen from high estate. It is natural, then, with returning and improved physical and moral perception they should begin to crave that which feeds the intellect and administers to the improved moral tone. So much, then, for the Reformatory, the work-house, the hospital, where we would place the chronic inebriate with- out friends and without means. But while the above institution will care for the chronic inebriate, it does not, and cannot, fill a want severely felt and long needed — how shall we deal with intoxicated persons arrested on the streets by the police? The usual metiiod is to arrest them, take them to the nearest police station, prefer a charge of intoxication, with or without disorderly conduct, record the case on the blotter, and commit the accused to a cell, to await the sentence of the justice. The following morning he is brought before the police court — if a first offence, and not paiticularly ag- gravating, sentence may be suspended — usually a fine is in- flicted — and if this cannot be paid, ten days in jail is the penalty. If the prisoner is an " old offender" and *' incorri- 258 DISEASES OF INEBRIETY. gible who has appeared before the justice probably several times, lie or she is sent to the "penitentiary" or the " Island " for a period not exceeding six months. To this method of dealing with intoxicated persons arrested on the street or other public place there are several objections ; in the first place, the average policeman is not a good diagnostician. Every case where the person is found stupid, dazed, or un- conscious, is to him a " drunk," and must be " run in." Hence, persons suffering from stupor, partial or complete, arising from certain cerebral conditions resultant from head injury, uraemic disease, or narcotics of any kind, unless these conditions are accompanied by marked evidence of assault, or other severe injuries, are apt to be mistaken for alcoholic intoxication. This is not the fault of the police — they are not diagnosticians, neither, indeed, can be — these cases oftentimes puzzle the experienced physician. The system that allows such a state of affairs to exist is at fault, not the policeman who fails to make a proper diagnosis. Certainly, to place such cases in a cell, and allow hours to elapse before the true condition of affairs is apprehended, is a grave and serious error. But even if the stupor is alcoholic, and the ar»-est there- fore legitimate, we maintain that the cell is an unfit place for such a person seriously intoxicated. Richardson, in his " Cantor Lectures," thus writes : " Whenever we see a person disposed to meet the effects of cold by strong drink it is our duty to check that effort, and whenever we see an unfortunate person under the influence of alcohol, it is our duty to suggest warmth as the best means for his recovery. " These facts prompt many other useful ideas of detail in our common life. If, for instance, our police were taught the simple art of taking the animal temperature of persons they have removed from the streets in a state of insensi- bility, the results would be most beneficial. The operation is one that hundreds of nurses now carry out daily, and CARE AND CONTROL IN TOWNS AND CITIES. 259 applied to our police-officers at their stations, it would enable them not only to suspect the difference between a man in an apoplectic fit and a man intoxicated, but would suggest naturally the instant abolition of the practice of thrusting the really intoxicated into a cold and damp cell, which to sucli a one is actually an ante-room to the grave." In view of this, in the " London Metropolitan District " the cells in whicli intoxicated persons are received are properly warmed in cool weather. In addition to this we maintain that every case of alco- holic coma or stupor should come under medical supervis- ion, that the police surgeon should make the diagnosis, — not the policeman who made the arrest — and appoint the proper remedial agencies. Too often the cell door has been shut and the prisoner allowed to " sleep off " his intoxication, and "the sleep that knows no waking" has come to him before morning. It has been suggested that in every large city there be established a central hospital, convenient of access, where all seriously intoxicated persons, or persons found dazed or stupid upon the streets from other causes, can be taken and receive prompt medical aid, and from thence, after they are sufficiently recovered, sent to their own homes, or if friend- less and homeless, assigned to the insane asylum, the ine- briate asylum, the charity hospital, or such institution as seems to be most appropriate for their condition. There is still another class, not directly coming under police supervision, to whom such central reception hospital would be a great boon — those who through alcoholic ex- cesses develop delirium tremens or acute alcoholic delirium, those living in boarding-houses whose means are limited, who cannot command nursing and medical attention. The regular city hospitals refuse such cases, except special arrangements are made and high rates are charged ; then only cases of acute alcoholism are taken — of course, chronic alcoholics are peremptorily refused. There is good reason 260 DISEASES OF INEBRIETY. for this; general hospitals have no special provision for cases of contagious disease, insane persons, or cases of alcoholism ; no padded rooms, no extra attendance, none of the appointments necessary for the care of such cases. The suburban inebriate hospital outside of the city is already tested to its full capacity with chronic cases of inebriety. It is at some distance from the city, and to enter a patient in its wards requires certain legal formalities, and therefore, time. Such a central hospital in the city, accessible at all times, especially to this class of cases under consideration, for which no provision is made at the general hospitals, would provide at least temporar}' care and treatment for insane or intoxicated persons found upon the street. It would be a channel through whicli the inebriate asylum, the insane asylum, or the general hospital, would receive its proper class and quota of patients. It would, as a " bureau of distribution," save much trouble now experienced in assigning insane persons to inebriate asylums, and alcoholic to insane asylums, as well as persons to either of these who might need the care of a general hospital. While not directly established for this work, it would in- directly do considerable of it. Besides this, the establishment of sucii a special hospi- tal mainlv for the treatment of such cases, would afford excellent opportunities to study alcoholism in its more acute forms. The capacity of such a hospital need not exceed fifty beds, as from it would be constantly sent out all cases not appropriate to it, and all cases assuming a chronic character. It would not be altogether dependent on the city for its support, as the friends of many would gladly pay for the privilege of having cases treated in its wards ratiier than in their own homes. Acute cases of alcoholism, after recovery from the immediate attack, should their cases warrant it, CARE AND CONTROL IN TOWNS AND CITIES. 261 could be assigned or committed to the inebriate asylum for *' chronic inebriates." Fortunately, we are not without precedent in this matter. The establishment of a special city hospital devoted to the care of "acute cases of alcoholic delirium," to which the police are directed at all times to bring persons found upon the streets seriously intoxicated or stupid from other cause, and all others who may desire to have their friends treated for acute alcoholism. " The Bureau d'Admission," of the department of the Seine, at St. Anne Asylum in Paris, of whicli Dr. Magnan is one of the two physicians, is an insti- tution to which no exact parallel exists in England or in this country. To it are brought all the cases of insanity pre- vious to their admission to the various public asylums, and all cases of acute delirium or mania whicii fall under the care of the police in Paris. It is here that they are exam- ined, and their admission or rejection decided upon. If admitted, they are drafted to the one or other of the asylums which is most suited to the class of the patient, or the form of his malady. The Bureau d'Admission is quite distinct from the St. Anne Asylum itself, and under altogether different admin- istration. In order to provide accommodation for the tempo- rary lodgment of patients on their way to other asylums, and also for the reception of the more acute cases, it is pro- vided with about fifty beds, and is fitted up in every way as a small asylum. Here there are brought all the cases of delirium tremens and "simple alcoholic delirium " which fall under the notice of the police, and a large number from the lower and middle classes, and here they are treated until tiieir recovery. Hence, it comes to pass that a very large proportion of all the cases of delirium tremens occur- ring in Paris and its vicinity come under observation here, and this not only in one attack, but again and again, and when at last by repeated attacks they have become mentally 262 DISEASES OF INEBRIETY. deranged or greatly weakened, they again come under notice for transference to asylums. The results of such opportunities of observation could scarcely fail to be productive of an increase of our knowl- edge, and their value is necessarily augmented by the fact of their being utilized by experienced alienists, and seen side by side with other forms of acute delirium. In addi- tion to the hospital wards there is an out-door department, where discliarged patients and others return for treatment of the various nervous disorders induced by their habits. This hospital does excellent work, but there should be a large suburban hospital for the control of the more chronic forms of inebriety, and persons treated for an acute attack "should not be allowed to return again and again, until their minds were weakened and they became thus fit sub- jects for the insane asylum." Such asylums, for long periods of commitment of chronic inebriates, exist in America, in England, in Australia, in New Zealand, and in Germany. Much interest is now manifested by the public and the legislatures of States on this all-important topic. It is nec- essary, therefore, that legislative effort be directed in the proper channels, and the inebriate, who constitutes so large a proportion of our population, should be laid hold of and dealt with systematically and scientifically — not as criminals, but as those deprived of their reason and their volition — those automatic in their actions, vicious in their propensities — a curse to the community in which they dwell. Restrain, control this class, and you reduce prodigality, want, disease, to a minimum, and produce the best sort of political economy, based on science and common sense. Allow this class their liberty, and you foster these evils, and encourage and prop- agate their results. Imprisonment, punishment — all punitive laws — have failed to abate or even mitigate the evil. Any effort directly based on fear of punishment or moral persua- CAKE AND CONTROL IN TOWNS AND CITIES. 263 sion will fail. We must place the evil on its true basis, — that of DISEASE, — and treat it accordingly. Yellow fever, cholera, small-pox we quarantine. We investigate the causes of epidemics, and we endeavor to remove that cause ; so with alcohol and its attendant evils. Punitive and restrictive laws should be directed against the manu- facture and sale of alcohol, not against its victim, the inebriate. How we shall care for the homeless, friendless, pauper inebriate, as he is presented to us in the acute and chronic forms of his malady, it has been the province of this paper to point out. CHAPTER XXVI. SAME MEDICO-LEGAL CONSIDERATIONS. It has become a maxim in law that drunkenness is no excuse for crime. The interpretations of phenomena by theology and medicine are undergoing modifications in con- sonance with the advancement in science and discovery, which distinguishes the age in which we live. Similar in- terpretations- by the law, however, are not so impressible. The movements of the law are necessarily cautious and de- liberate. The legal principle which denies to drunkenness any liberty with respect to crime, must have its reason in some presumed expediency, in the absence of exact knowl- edge. For the true principles which underlie the several and distinct varieties in motive and intent, inciting the inebriate in the gratification of his unnatural appetite, are even now undergoing study and analysis. The law has been unable, hitherto, to offer a comprehensive and satis- factory explanation and definition of drunkenness ; and its dictum, therefore, that inebriation is no excuse for crime, must be open to suspicion. It is certain that a man indubitably drunk is not in his right mind, and that he can not, by any power within him- self, either mental or physical, conduct himself as he would do when not intoxicated. It is also certain that his departures from the lines of right reason are fundamental and not frivolous. But drunkenness is a state of mind and body usually of brief duration. The sober mind has means within itself of study- ing the nature of drunkenness between spells, as well as 265 266 DISEASES OF INEBRIETY. observing it in others. It is capable of perceiving that the use of alcoholic liquors will induce a condition of the men- tal faculties wherein motives and intent? are unusual and unsound, as well as beyond volitional control. But the questions arise : Are there not radical differences in the motives which impel to drunkenness ? Is not intoxication, very frequently indeed, the result of the demands of a disease or of an urgency in the feelings which an attending imbe- cility of mind is unable to control or overcome ? If these interrogatories really fore-shadow actual facts, then it must be that there are important exceptions to the proposition that drunkenness is no excuse for crime ; for the inebriate may then be not merely irresponsible, abstractly, when drunk, but he may be irresponsible for the imbecility of will which so readily yields to the demands of the neu- rotic constitution. In the neurotic constitution even slight intoxication is often succeeded by an utter blank in the memory. This withdrawal of the mind from the direct line and knowl- edge of conscious life implies radical disabilities in the assumption of responsibility for conduct. Drobisch ex- plained clearly the general nature of the law of association in psychology in the language following : Psychology shows that not only memory and imagination, but judgment, reasoning, conscience itself, and, in general, all higher activity and all development of the mind rest upon the association and reproduction of states of consciousness ; that this explains also the different variations of feeling, emotion, desire, passion, and rational will. But these explications are supported by generalities that have always an indeterminate character. This arises from their lack of quantitative determination. Whatever, therefore, is con- ceded or permitted to a congenital infirmity of mind in its relations with the world at large, must also be accorded to constitutional incapacity in any special direction. The well-defined neurotic or spasmodic drunkard is an imbecile SOME MEDICO-LEGAL CONSIDEKATIONS. 267 in respect to his desire for intoxication ; for, in the con- genital inebriate, the association and reproduction of states of consciousness neitlier are, nor can they become, witli respect to his special besetment, eitlier normal or manage- able. In general terms it may be said that inebriety is origin- ally — that is, anterior to its hereditary descent in varying forms — the outcome of very serious bodily injury, but more especially injury to the head. The history of the late civil war abounds in exemplifications of this fact. Certain physi- cal wounds affect directly portions of the brain, or they may withdraw from normal correspondence and relationship with the brain to important parts of the body elsewhere. The means, and measure, and quality of consciousness, through many channels of sensation and association, are thus perma- nantly destroyed. Thus there are produced radical defects in consciousness, which in respect to inebriety prevent those conservative mental operations and associations upon which all higher activity and all development of mind rest. I have said neurotic inebriety is primarily occasioned by some physical injury, possibly in remote ancestry. This includes, of course, such injuries to nervous integrity as may arise from any adequate cause, perhaps not technically, yet in reality physical, as prolonged grief, great nervous shock, excessive study, protracted and profound disease, malaria, and many other recognized sources of that peculiar state of nervous instability and inadequacy which goes under the general designation of the neurotic constitution. Absence of function begets incapacity to act through sheer debility of nerve, or even through atrophy of substance. Dr. Livingston, after years of absence amongst the black tribes of Africa, says that upon coming into the presence of his countrymen he was at home in everything except his own mother tongue. He seemed to know the language perfectly ; but the words he wanted would not come at his call. It is difficult to divest the mind of the idea that the 268 DISEASES OF INEBRIETY. inebriate is really capable of mastering his morbid proclivity at will. And that there may be — in view of the lack of quantitative determination in the character of the nervous disability in the neurotic inebriate — certain instances wherein the defect is not overmastering, seems probable. Yet this very qualification may doubtless include innumer- able instances in which voluntary restraint is impossible. No man by taking thought can add one cubit unto his stature. Neither can a man by any process of reasoning, or any effort of will, change the functions appertaining to physical defect or pathological deterioration into the ways of normal and physiological life. It is impossible to discuss the exact time when the brain becomes diseased by alcohol and its victim loses self-con- trol, or what quantity of that stimulant a person can use before becoming a dipsomaniac. This point of time can be no more satisfactorily arrived at than the true time required for the production of yellow fever by the application of its exciting cause. Some constitutions would be affected in five minutes. In others it would require weeks or perhaps months of exposure to miasmata before the individual would discover the premonitory S3'mptoms of the disease. So it is with different individuals who are in constant use of alcoholic stimulants. It is impossible for the physician to state when the con- stitution is first affected by disease. The dividing line between health and disease has never been determined. Nor can it ever be defined. The physiologist has never been able to draw the dividing line between sanity and insanity, or to determine how much of the exciting cause it requires to produce a morbid condition of the brain. These nice distinctions in regard to the pathology of dis- ease do not enter into the discussion in reference to the im- portance of asylums for the control and medical treatment of dipsomaniacs. Neither can we point out the dividing line where the SOME MEDICO-LEGAL CONSIDERATIONS. 269 moral responsibility ceases, and the irresponsibility begins in the use of alcoholic stimulants. The time, when an institution can reach the dipsomaniac is when he has lost self-control, and the law regards him as a dangerous citizen, or when he can be induced to enter the asylum voluntarily. We contend that when the brain is diseased from defect- ive nutrition, by any animal or vegetable poison, by any great shock on the nervous system impairing the nervous fluids of the body, there will be a corresponding disease of mind, which disease will develop all tlie peculiar types, stages, and phases of insanity, from the most inoffensive to the most furious and dangerous. It matters not how this disease may have been induced, wliether by stimulants pre- scribed in sickness, or by the influence of social friends ; whether under extenuating circumstances, or in full view of the terrible penalty which this malady inflicts on its victim ; the State is equally bound to protect society against the in- sane acts of this dipsomaniac. He should be committed to an asylum for restraint and treatment adapted to his physical and mental condition. All the laws and penalties which a State can enact against crime committed by the dipsomaniac will never prevent him, while at large, from committing murder, arson, or theft, or from taking his own life. Why, then, should our State allow its citizens to go at large, when they have lost self-control, and when daily experience shows that it is not compatible with private and public safety for them to remain at liberty ? Does the State bring to life the murdered family by simply going through the accustomed forms of judicial procedure, in order to punish the man for what he cannot be responsible, or place him as a criminal at the bar, when his testimony would not be received in the witness box, or find out, too late, that he really is a maniac, and send him at last to an asylum as a criminal lunatic. 270 DISEASES OF INEBEIETT. The only true and enlightened policy for the State is to provide asylums for tliis class of insane. What IS it ? is the question of the hour. To find the answer, let it first be determined what or who are inebriates. That there are thousands of persons who consume intoxi- cants habitually and constantly, who are never visibly intoxicated, is a very obvious truth. It is nevertheless true, that there are many who, by nature and constitutional bias, are inebriates, who have never taken an inebriating draught, but who, knowing theijiselves, and their morbid tendency, avoid the danger of excess by absolute and perpetual abstin- ence. Not a few such persons may be found among intelligent and careful people, with whom each day is a day of conflict — of conflict with themselves and their environment. Tliey are a multitude of heroes, whose battles with self will never be known, and the record of whose conquests will never be made. Such cases have their analogues in various forms of morbid inheritance, only two of which need now be men- tioned, insanity and pulmonary consumption. The natural history of insanity and inebriety is so simi- liar that it is sometimes difficult to draw the line cf separa- tion. Indeed, they are so near to each other as to admit in some cases of an equal place in nosology, as, for example, in the use of the terms '* insane drunkenness " and "drunken insanity," both representing kindred pathological conditions. The relationship is so patent even to the unprofessional observer, that I need dwell no longeron this point than to allude to a striking inconsistency in the law, as viewed from a medical standpoint. If I understand its meaning, the law discriminates between common drunkenness and dipso- mania, but fails to recognize the likeness between dipso- mania and insanity, or, in other words, it does not see a similarity between insanity from drink and insanity from other causes, though the manifestations may be similar. It assumes that the dipsomaniac is a voluntary demon or SOME MEDICO-LEGAL CONSIDERATIONS. 271 drunkard, and if he will, he may avoid the paroxysms that characterize the disease. Science, however, declares a dipsomaniac, or an inebriate in the medical sense, to be what he is from an impaired or defective will, that is unable to resist the " nerve storm" which assails him at intervals, that he cannot always antici- pate, as is the case in hysteria, epilepsy, etc. In consequence of this error, the law provides in the same statute for habit- ual drunkenness and insanity, making a criminal act com- mitted by an insane person so far different irr its results from the same act committed by an inebriate, as to warrant the commitment of the former to an asylnm, while the pen- alty inflicted upon the latter may be imprisonment for life in a penitentary, or it may be hanging by the neck till he is dead. The analogy presented by pulmonary consumption may not, in the view of some, be so decided, and hence I invite attention to the early symptomatology and hereditary signs of tiie two disorders. Thousands are being born with a decided and well-marked consumptive diathesis, but who, knowing tliemselves and their family history, adapt them- selves to such hygienic and climatic methods of living as tend to counteract the progress of the disease, and thus avoid its fatal ravages. Such persons, however, are con- sumptives by natural descent, who would go steadily on to a consumptive's lingering death, but for the knowledge of their tendency to it, and their ability to avail themselves of means to resist its approaches. While it is interesting to observe these analogues, and while the very fact of likeness serves as confirmatory evidence of disease, there is ample testimony from distinguished sources to fix the fact of dis- ease independent of any likeness to other morbid condi- tions. Dr. Quain defines disease to be " any deviation from the standard of health, in any of the functions or com- ponent materials of the body." Dr. Norman Kerr says in his recent work on inebriety, 272 DISEASES OF INEBRIETY. "In drunkenness of all degrees, and every variety, the Churcli sees only sin ; the world, only vice j the State, only crime. On the other hand, whatever else any intelligent medical practitioner beholds in such cases, he generally dis- covers a condition of disease," In our own country, the current medical opinion favors the same view, and I am convinced that it is gaining a firmer hold on the public mind in all departments of our social and civil life. It remains for the legal and the judicial sentiment of the land so to classify alcoholic intoxication as to remove it from the do- main of morals, not even regarding it as a species of moral mania, but to accord to it its legitimate place as a physical disease. For our present purpose, at least, it is assumed that we are agreed as to the abstract question of disease as applied to inebriety, but it becomes us to extend our inquiries a little further, that we may ascertain to what class of disor- ders it belongs. By common consent it is assigned to the realm of neurotic disorders. It affects most immediately and seriously the nervous system. Here, again, we may pause a moment to notice a fact concerning the complicated nervous system, which I think is not fully appreciated out- side the medical profession. I refer to the sympathetic system of nerves as distinct and largely independent of the motor system. In order to apprehend the ravages of alco- hol upon the sensitive nature of man, it is essential that we understand the functions of the vital, as distinct from the mechanical or automatic forces and movements of the body. I take it to be an admitted principle of law that to consti- tute a criminal act, the will must consent to the perform- ance of the act, and in the study in which we are now engaged it is highly important that we discriminate as I have suggested ; that we appreciate the difference between the nervous system, which has to do with vital forces and functions, and the other nervous system, which does not control or influence vital forces or functions. SOME MEDICO-LEGAL CONSIDERATIONS. 273 The inhibitory, restraining power resides in the series of nerves which is specifically assailed by alcohol, when taken into the body, and this is the prime fact in the whole matter of responsibility, to which the law of the land does not seem to attach importance. I read in my Blackstone that "all the several pleas and excuses which protect the committer of a forbidden act from the punishment which is otherwise annexed thereto, may be reduced to this single consideration — the want or defect of will. Indeed, to make a complete crime cognizable by human law, there must be both a will and an act." In the time when this wholesome doctrine was proclaimed, the dogma of disease, as applied to in- ebriety, was not considered. Intoxication was taken to be a voluntary act, and hence it was said of an inebriate that " what hurt or ill soever he doeth, his drunkenness doth aggravate it." This doctrine may be to-day orthodox in law, but in med- icine it is not, and herein lies the difference between law and medicine. Occasions or opportunities like the present are meant to reconcile the two professions to the acceptance of this wiser doctrine and a more humane practice. But the question arises here, and is submitted from the legal side. If inebriety is not to be punished, how will society be protected from the assaults of the drunkard ? Judge Davis says : " No disease excuses any man for the commission of crime. A man in the last stages of consump- tion is to be hanged for a murder as surely as though he was in perfect health, and no disease by reason of its own existence can, under any circumstances, excuse any man for the commirsion of crime. Hence, to establish that it is a disease is only to put it on the exact footing on which all other diseases stand in respect of violation of law and their punishment." If, then, insanity being considered a disease, and inebriety be taken by law to be also a disease as well defined and understood, we should gain all that we ask for. Then I sliould hail this utterence from such a distinguished 274 DISEASES OP INEBRIETY. source as the keynote of a new doctrine, which should be taken up by the courts of law and sounded with accumulat- ing force and rhythm till the jurisprudence of the whole range of disease and crime in their joint relation shall be infused by its healthy tone. While it proposes that society shall be protected from the voluntary and deliberate criminal by punishment, be it hanging or what else, it will protect society from the invol- untary and unconscious criminal by isolation in a hospital or asylum provided by the State for its unfortunate citizens who have come into this world with an organization that is out of harmony with the ethical and civil relations which the law sanctions and provides for. When the philosophy of law and the science of medicine shall join hands together to create a jurisprudence founded on such a basis, it will be a step toward a state of society that is much to be desired, and will be doing more in the direction of relief from the blight of intoxication than can, in the very nature of things, be done by the methods so ineffectually put forth at this time. When alcohol enters into the human body in excess, its affinity for nerve structure is manifest in its grasp upon the inhibitory forces as among its very early influences. The will is the citadel of the soul, by which life and conduct are guarded and guided, but when it is seized and made captive, to obey only the behests of this destructive force, the victim is lost to himself, and acknowledges that he is enslaved. The relation of the human will to the nervous system is sadly misjudged. The wonderful network of nerves known as the sympathetic system acts independently of the will. It presides over vital functions. It has to do with the forces of life with which the will has nothing to do. The heart beats, the stomach digests, all the vital organs fulfill their respective offices without any reference to the will. It works while we sleep, and the vital functions are performed SOME MEDICO-LEGAL CONSIDERATIONS. . 275 in our unconscious rest. By its side the will is powerless. If it presides over appetite, its behests are absolute. The inebriate, with inherited or acquired passion for stimulants, or for their hypnotic effect, cannot control his longing when it asserts itself. The hungry man who is starving for bread cannot, at his will, bid his hunger depart. The true inebriate, when his restless nerves and sinking spirits and burning desire demand repose and satis- faction, must obey the call. He obeys though his will, his conscience, his judgment, his past experiences, his moral sense, all join in earnest protest. Is it depravity of his nature or infirmity of his will ? A wide distinction exists between depravity and pravity of will. Depravity signifies a state of natural debasement, with- out any cause. The idea of a cause is precluded. It is natural. Pravity signifies a departure from a right purpose, for which a cause is implied which is generally subjective. Indeed, an impaired, feeble will is frequently the first symp- tom of an approaching debauch. CHAPTER XXVII. MEDICO-LEGAL QUESTIONS (CONTINUED) — LAW AND RUL- INGS OF JUDGES. In a discussion in which the question is to be considered by such able medical men from the medical side or stand- point, it has seemed to me that it would be of interest to both professions, as well as to laymen, to have the inquiry made as to those relations which attach by law to inebriety, as well in the civil and domestic relations of the inebriate, as in regard to crimes committed by persons while acting under the influence of intoxicants, or while in a state of intoxication. What, then, is the present legal status of the question ? I shall briefly state (but have neither opportunity nor space to discuss) wliat I believe to be the law upon the sub- ject ; citing and grouping authorities — the civil side first, and the question of criminal responsibility second. I. Civil Relations, i. Intoxication was regarded by the common law, when complete and characterized by un- consciousness, as a species of insanity. Lord Coke's fourth manner of " 7ion compos mentis " was " 4. By his own act as a drunkard." Deliriutn tremens, which results directly from habits of intoxication, is in law considered to be a form of insanity, and this has been repeatedly held by the courts. It has always been a well-settled rule of law that no per- son can make a contract binding upon himself while he is wholly deprived of his reason by intoxication. This would 277 278 DISEASES OF INEBRIETY. be true as to deeds, wills, all instruments and obligations of every kind. This rule is not changed where the intoxication was not procured by the other party to the contract, but is voluntary on the part of the drunkard. By tlie common law, as well as by the New York stat- ute, a testator must, at the time of the execution of a will, bj of ^^ sou?id niind and memory," and it is as requisite to have the presence of a '''disposing memory," as a *' sound mind." {b) By common law and by statute law an intoxicated person is thereby rendered incompetent as a witness. The statute law usually classifies sucli intoxicated persons as lunatics, and the provisions frequently apply similarly to each, and' to both. (<:) In the marriage contract, which in some is treated on different grounds from all other contracts, from the neces- sity of the case and consequences upon consummation, the sound general rule has been, that if the party was so far intoxicated as not to understand the nature and consequences of the act, this would invalidate the contract. 2. The analogy between lunacy and total intoxication, or even habitual drunkenness, is doubtless most marked in the statutes of the various States, regarding the care and custody of the person and estates of lunatics, idiots, and habitual drunkards. (a) By English law the Lord Chancellor, as the direct representative of the Crown, has always exercised the right of assuming the custody and control of the persons and estates or all those who, by reason of imbecility or want of understanding, are incapable of taking care of themselves. Writs de lunatico inquirendo were issued in cases to inquire whether the party was incapable of conducting his affairs on account of habitual drunkenness. The Supreme Court of every American State would doubtless have the right which the Court of Chancery exercised under the law of England in the absence of any LAW AND KULINGS OF JUDGES. 279 Statute law. This must be so in the nature of things in American States ; the principle has been exercised and adjudicated on in Kentucky, in Maryland, Illinois, Indiana, and North Carolina. The Legislatures of the various States have vested this power by statutory enactments in various tribunals, for example in New York, by the old law in the chancellor ; in New Jersey, in the Orphans' Court ; in South Carolina, equally in the law and equity side of the courts, and now in New York, where the distinction between law and equity has been abolished, in the Supreme Court, which exer- cises it. It will be observed that in many of the American States the habitual drunkard, even, is classified and treated under the same provisions, and in the same manner as the lunatic and the idiot, notably in Pennsylvania, New Jersey, Mary- land, Illinois, New York, and many other States. Taking New York as a fair illustration of the principle, it has been held by the courts, that all contracts made by habitual drunkards who have been so adjudged in proceed- ings de lunatico inquirendo are actually void. And that the disability of the habitual drunkard continues after the committee has been appointed, even when he is perfectly sober and fully aware of the nature and consequences of his acts. It has also been held that habitual drunkenness being established, it x'?, prima facie evidence of the subject's inca- pacity to manage his affairs. We may then assume, in considering the medical juris- prudence of inebriety, that the law has always regarded and treated intoxication as a species of mental derangement, and has considered and treated the habitual or other drunkard as entitled to the special care and protection of Courts of Equity, in all matters relating to his civil rights, his domestic concerns, his ability to make contracts, his 280 DISEASES OF INEBRIETY. intermarrying and disposing of his property, by deed, gift, or devise. The law has gone farther, for it has thrown round him its protecting arm and shield, when it is satisfied that he has become so addicted to drink as to seriously interfere with the care of his estate, and the courts have then come in and taken absolute control of both person and estate of drunkards, in their own interest and for their presumed good. Medical men should keep in mind the distinction run- ning all through the law between insanity and irresponsi- bility. The medical view, that irresponsibility should follow where insanity exists, has nowliere been conceded by the law, and this distinction must be borne in mind in the sub- ject here under consideration. II. Criminal Relations. This brings us to the second question : The relation of the inebriate to the criminal law for illegal acts, committed while intoxicated, which seems more harsh in its practical effect than the principles which govern him in his civil and social relations to society and the State. This seeming hardship, however, is due to the capacity of the drunkard, considered objectively, for wrong-doing. In the one case his position as a civil agent is that of a unit of society merely — one who is, as it were, to be "saved from himself"; in the other case, the criminal aspect of the drunkard, it is the weal of society which is to be conserved and protected. I. That form of intoxication which results in the total or partial suspension of, or interference with, the normal exercise of brain function, is regarded, at law, as mental unsoundness, and sometimes amounts to a species of in- sanity. It has been held at law to be a voluntary madness, caused by the willful act of the drunkard, and the decisions have been uniform, that where reason has been thus sus- pended, by the voluntary intoxication of a person otlierwise LAW AND KULINGS OF JUDGES. 281 sane, this condition does not relieve him from the conse- quences of his criminal acts, or, more carefully stating it^ from acts committed by him in violation of law, while in that state. (a) There are decisions which go to the length of hold- ing that the law will not consider the degree of intoxica- tion, whether partial, excessive, or complete, and even tiiat if the party was unconscious at the time the act was com- mitted, such condition would not excuse his act ; and, in some cases, judges have gone so far as to instruct juries that intoxication is actually an aggravation of the unlawful act rather than an excuse. But the better rule of law now undoubtedly is, that if the person, at the moment of the commission of the act, was unconscious, and incapable of reflection or memory, from intoxication, he could not be convicted. There must be motive and intention to constitute crime, and in such a case the accused would be incapable from intoxication of acting from motive. [d) The reasons upon which the rule of law rests, may, with great propriety, be considered, and should be carefully studied, before any attempt at criticism is made. 1. The law assumes that he who, wliile sane, puts him- self voluntarily into a condition, in which he knows he cannot control his actions, must take the consequences of his acts, and that his intentions may be inferred, 2. That he who thus voluntarily places himself in such a position, and is sufficiently sane to conceive the perpetra- tion of the crime, must be assumed to have contemplated its perpetration, 3. That as malice in most cases must be shown or established to complete the evidence of crime, it may be inferred, from the nature of the act, how done, the provoca- tion or its absence, and all the circumstances of the case. In cases where the law recognizes different degrees of a given crime, and provides that willful and deliberate inten- 282 DISEASES OF INEBRIETY. tion, malice, and premeditation must be actually proved to convict in the first degree, it is a proper subject of inquiry whether the accused was in a condition of mind to be capable of premeditation. Sometimes it becomes necessary to inquire whether the act was done in heat of passion, or after mature premedita- tion and deliberation, in which tlie actual condition of the accused and all the circumstances attending his intoxica- tion, would be important as bearing upon the question of previous intent and malice. () gradual reduction ; {c) rapid reduction. 329 330 DISEASES OF INEBRIETY. Under the first the sufferings are intolerable, the pros- tration great and dangerous and it does not offer any great security against relapse. In the majority of instances tlie rapid reduction is the wiser means between the two extremes. The rapidity should vary with the case, and should be such as not to involve extreme suffering or great prostration. 3. We have to deal in all cases of long standing with an emaciated body and starving nerve centers. At the same time we have complete anorexia and feeble digestion, perhaps nausea and vomiting. The feeding of the patient becomes, therefore, one of the most important, and perhaps most difficult parts of the treatment. Often it is well to begin with exclusive milk diet (pep- tonized, if necessary). Systematic feeding of small quanti- ties at frequent intervals is usually best. Confinement to bed during early part of treatment will promote the nutri- tion. At the same time it reduces to the minimum the tax upon the shattered nervous system. For the same reason, as well as for the sake of preventing the clandestine supply of the drug, seclusion is best until convalescence is well estab- lished. The good results of the "rest treatment," as advocated by Mitchell, /. e., seclusion, confinement to bed, forced feed- ing, massage, and electricity, with gradual (usually rapid) reduction of the drug, are permanent. 4. The use of various mechanical agencies for the relief of pain, quieting" tlie nervous system, inducing sleep and pro- moting nutrition — massage, electricity (both faradism and galvanism), hot baths, Turkish baths, tlie cold shower-bath. Dr. Jennings recommends the hammock for the restlessness and desire for constant motion, so often a distressing symp- tom. 5. Medicinal agents to meet the various indications of each case. The observations of Drs. Jennings and Ball, of Paris, OPIUM INEBKIETT (cONTINDEd). 331 upon the sph3'gmographic tracings of the pulse of habitues we believe, have laid the physiological basis for a rational system of medication. These observations, which have been confirmed by others, show, " that the pulse of a morphine habitue in a state of privation .... caused by want of cardiac impulsion, together with a resistance to the passage of the blood in the vessels. A hypodermic or morphia given at this moment restores the normal state of the circulation The study of these tracings suggested the use of cardiac tonics and stimulants as substitutes for the morphia during the progressive reduction." The drugs chosen were : " Spar- teine, on account of the facilities it offers for hypodermic injection, and producing thus a rapid and evident effect ; and trinitin, because of its congestive effect on the head and its calorific effect upon the body generally." D«'. Jennings uses these remedies in the gradual suppres- sion of the drug when the reduction has reached such a degree as to bring on the symptoms of deprivation. It is not to be understood that these drugs take the place of morphia, i. e., that it can be at once omitted without the usual suffering ; tliey are but aids in mitigating that suffer- ing by counteracting some of the circulatory disturbances upon which it largely depends. The evidence of clinical experience is largely in favor of heart tonics and stimulants rather than of sedatives. In the case reported, no sedatives were given, yet after the first few nights, sleep was good. The glonoin had certainly a good effect, being given at the time when the symptoms of the craving came on. Quinia was used as a stimulant to the heart and the cerebral circulation. Strychnia was given as a heart tonic after complete withdrawal of morphia. When nervousness is great, or insomnia does not yield to other means, drugs may be necessary. In these instances, cannabis indica in large doses {}i to i drachm of fl. ext.)^ 332 DISEASES OF INEBEIETT. sulfonal, chloralamid or bromides will often render good service. Chloral is used by Erlenmeyer, condemned by Aurleck and others. Dr, Jennings seems latterly to have usually substituted digitalis /^r^.y forspartein hypodermati- cally, Quinia has seemed to me in many cases of distinct value. Strychnia is one of the best heart tonics in the pharmacopoeia. Obersteiner is almost the only w^riter of note who now speaks well of cocaine. If used at all, it should never, of course, be placed in the hands of the patient himself. The f^uid extract of coca has been highly spoken of by several writers to relieve restlessness and depression. Valerianate of ammonia has been a common favorite since the time of De Quincy. This method, which, so far as we are aware, is original with and peculiar to Dr. Mathison, is merely a new applica- tion of a well-established principle, for the power of the bro- mides to subdue abnormal reflex irritability is so constant that it may be looked upon as an invariable sequel of such medication. Dr. Ed. H. Clarke, in his valuable treatise on the bromides, says : " Diminished reflex sensibility, however different physiologists may explain the fact, is cne of the most frequent piienomena of bromidal medication that has been clinically observed, and is, therapeutically, one of the most important." The testimony of other distinguished observers is to the same effect — Gubler, Guttman, Laborde, Voison, Damourette, Eulenberg, Claude Bernard, Brown- Sequard, Echeverria, and Hammond all giving evidence as to the power of these agents to impair the control of the spinal cord over reflex manifestations, and, at the same time, exert a marked influence over the general nervous system. Admitting that the symptomatology of opiate abandonment pertains almost exclusively to the functions over which the bromides exert so decided a control, we have in the treatment of opium inebriety a new field pre- sented for the exercise of this valuable property, and the OPmM INEBRIETY (cONTINTJEd). 333 fact, proven conclusively by our experience, that it ^(^^j- exert this happy effect, fully supports the idea advanced as to pathology of this disease. In speaking of the bromide of sodium, let it be under- stood that we refer entirely to the influence of the continued dose, by which we mean its administration three times in the twenty-four hours, at regular intervals, so as to keep the blood constantly charged with the drug. A most important difference, physiological and therapeutical, exists between the effect of this mode of exhibition and that of the single dose, or two or three doses so nearly together as to form practically one. for in the former case the system is constantly under the bromide influence, while in the other, the drug being largely eliminated in a few hours, the blood is nearly free from it a large portion of tlie time. Results obtainable from the continued use cannot be gotten from the single dose, and, as a consequence, its value is far greater in the disease under consideration. Again, the action of the continued dose being somewhat remote, three to five days usually elapsing before there is decided evidence in this direction, much more desirable results are secured by its employment for several days/r/^r to an entire opium abandonment, meanwhile gradually reducing the opiate, than if the withdrawal be complete and then reliance placed on the bromide to control the result- ant irritability ; for, in one instance, the maximum sedative effect is reached at the period of maximum disturbance from the opium removal, and its counteracting and con- trolling effect is far in excess of that to be had from its employment subsequent to the lighting up of the nervous irritation. What, then, we style preliminary sedation forms a peculiar and most valuable feature in our administration of the bromide, and it is this particular point we commend to you, our experience having convinced us we have in it an unequaled means of obviating the suffering incident to the treatment of this disorder. v 334 DISEASES OF INEBRIETY. The value of the various bromides depends'on their pro- portion of bromine. Bromide of potassium contains 66 per cent., sodium 78, and lithium 92 per cent. We should, therefore, expect a more powerful influence from the latter agent, and, according to Wier Mitchell, it has a more rapid and intense effect. Bromide of sodium being richer in bro- mine, and pleasanter to the taste, we prefer it to potas- sium. Either of the bromides, in powder or concentrated solu- tion, is somewhat irritant, sometimes provoking emesis, and, in any event, delaying its absorption. A practical point, then, is that it be given largely diluted. Dr. Clarke says, " There should be at least a drachm of water to each grain of the salt." We give each dose of the sodium in six or eight ounces of cold water, and have never known it to cause vomiting. Another important feature relates to the time of its employment. We usually administer it at 10 a. m., 4 and 10 p. M., or half an hour before each meal. Given thus, largely diluted, it is probably absorbed in half an hour, and the effect of tlie continued dose rapidly secured. To produce the requisite degree of sedation within a limited period, it is essential that the bromide be given in full doses. I am convinced that failure in its use, in any neurosis, is very often due to a non-observance of this point. Our initial dose of the sodium is 30 grains, twice daily, time and mode as stated, increasing the daily amount 30 grains each day, i. e., 40, 50, 60 grains and continuing it eight days, reaching a maximum dose of 100 grains twice times in the twenty-four hours. It is then discontinued, but its sedative effect persists and somewhat increases for two or three days following, and then begins to decline. This period may last a week or more depend- ing on some state of the blood and power of elimination. During this week of bromidal medication, the usual opiate is gradually reduced, so tliat oa the seventh or OPIUM INEBRIETY (oONTINDEd). 335 eighth day it is entirely abandoned. A decrease of one- third or one-half the accustomed daily quantity is made at the outset, experience having shown that habitues are almost always using an amount in excess of their actual need, and this decided reduction occasions little or no in- convenience. Subsequently, the opiate withdrawal is more or less rapid according to the increasing sedation, llie object being to meet and overcome the rising nervous disturbance by the growing effect of the sedative — in other words, maximum sedation at time of maximum irritation. Having secured the sedative effect desired, the object is to eliminate the bromide as rapidly as possible, and as the skin and kidneys form the only outlets, recourse is had at once to diaphoretics and diuretics. Of the former, hot and steam baths are to be relied upon. And, of the latter, digi- talis, in infusion, or, if bulk be objectionable, Squibb's fluid extract combined with potass, acet. and spirits aether nitrosi. The bromide itself increases renal secretion, and, aided by the others, it passes from the system in a few days. The bromide and opiate having been discontinued, restlessness, more or less prominent, from 20 to 56 hours, invariably sur pervenes. It is controlled by codeine, i to 3 grains sub- cutaneously, or by mouth, every 2 to 4 hours, and this is continued, decreasing the dose or increasing the interval till no longer needed, but is greatly relieved by hot — not warm — baths, temperature 110° to 112°, 15 to 30 minutes duration, repeated as required. They are often signally effective. We have known a patient fall asleep, snoring vigorously, while in a bath. Sleeplessness is always more or less prominent after opium abandonment. During the first six nights, sulfonal or trional in 30 or 40 grain doses is given. Afterward, such hypnotic as seems best suited to the case ; cliloral is most effective, in 20 or 30 grain doses at bedtime. Often smaller doses may be given at intervals of two hours until sleep follows, with good results. 336 DISEASES OF INEBRIETY. A peculiarity of this insomnia is, that it is most marked in the early morning. Slumber comes readily enough at niglit, but patient awakes at two, three, or four oclock, and finds further sleep impossible. Often it is well to defer the sleeping draught until this time. This wak- ing tendency gradually diminishes, and ultimately dis- appears. Chloral, given during the early opium abstinence, has, with us, not acted kindly as a hypnotic, but produced a peculiar intoxication, though we have never noted the wild, maniacal delirium mentioned by Dr. Levenstien as occur- ring during this period in his cases. As soon as possible it should be discontinued, and sleep secured by a fatiguing walk, a half hour's warm bath, a light lunch, or glass of milk — one or all, before retiring. For three or four days following the opiate withdrawal, the diet should be exclusively of milk combined with lime- water — one or two ounces, with one or two drachms respect- ively — every hour or two. It is very seldom rejected, and is preferable to beef tea, or anything else. Afterwards, a full, solid diet may be resumed, soon as practicable. While diarrlicea is the decided exception under this plan of treatment, we still deem it best to keep the bowels in good condition, and administer the first night, a mercurial cathartic sufficient for several full evacuations, followed, during the bromide giving, by daily laxative enemas, or doses of Hunyadi water. Debility, of varying d egree, due to the opium abstinence, and bromide relaxation, is among the sequelae. It decreases with the increasing bromine elimination, aided most effect- ively by general faradization, twenty minutes morning seances daily, after the restlessness subsides, and strychnia I-20 gr. thrice daily, combined with iron, quinine, phospho- rus, digitalis, or cod liver oil, as most required. The following formulae are valuable : OPIUM INEBRIETY (CONTINUED). 337 Be. Strychnine, two grains ; Muriated Tinct. Iron, five ounces ; Tinct. Digitalis, and Glycerine, of each, two and one-half ounces. M. Dose — One to two drachms, three times daily. 5. Strychnine, four grains ; Dialized iron, five ounces. M. Dose, one-half drachm, ter in die. R. Strychnine, two grains ; Dilute Phosphoric acid, and Syrup of Ginger, of each, two and one-half ounces. M. Does — One drachm thrice daily. R. Pyrophosphate of Iron, 5 to 10 grs., Quinme, 2 grs. at a dose. M. Pill, or solution, three times a day, if the appetite be slow in returning. 'Be. Comp. Tinct. Quassia, one drachm ; Tinct. Capsicum, ten drops. M. For one dose, diluted, 20 minutes before each meal. Strychnia is not advisable during the bromide adminis- tration. Being decidedly antagonistic — one causing relax- ation and deficient reflex excitability, the other, just the reverse — the desired sedative effect may be materially delayed if they be given together. Subsequently, it is the most valued general tonic at command, and may be con- tinued in varied combination for weeks. With the strictly medicinal course are to be employed a full nutritious diet, out-of-door exercise, especially walking, and varied social enjoyments — in fact, anything that can exert a roborant effect on mind or body. Surprise may be expressed, and objection made regard- ing the extent of the bromide doses, but the fact must never be overlooked that we are not to be governed in the giving of any remedy by the mere numerical amount of drops or grains, but by the effect produced. Again, I am led to think that one effect of opium addiction is a peculiar non-suscep- tibility to the action of various nervines, necessitating their more robust exhibition to secure a decided result. More, and most important of all, under the influence of certain 338 DISEASES OF INEBKIETY. abnormal conditions, doses which ordinarily are toxic be- come simply therapeutic. The annals of medical literature abound with illustrations in support of this statement, and among the most striking may be noted the following : Dr. Southey read before the Clinical Society of London notes of a case of idiopathic tetanus, which occurred in a boy ten years old. The first symptoms of trismus were observed two days after a severe fright and drenching due to the up- set of a water-butt. They steadily increased up to the date of liis admission to St. Bartholomew's hospital, upon the eighth day of his illness, when the paroxysms of general opisthotonos seized him at intervals of nearly every three minutes. Each attack lasted from fifteen to thirty seconds* and although between the seizures the muscles of the trunk became less rigid, those of the neck and jaw were maintained in constant tonic cramp. The patient was treated at first with chloral, ten grains, and bromide of potassium twenty grains, every two hours, and, afterwards, with the bromide alone in sixty grain doses every hour and a-half. When about two ounces were taken in the twenty-four hours, the attacks became less frequent, but at first each separate seiz- ure was rather more severe, and upon the evening of the eleventh day, he was able to open his mouth better. On the thirteenth day the bromide was decreased to twenty grains every three hours, and on the fourteenth day, was discontinued altogether. When the bromide had been omitted for twenty-four hours, the attacks returned at inter- vals of an hour, and the permanent rigidity of the muscles of the neck was re-established. His condition now steadily became worse, so that on the eighteenth day of his illness it became necessary to resort to the previous large doses — one drachm — every hour and a-half. After three such doses, the expression became more natural, and he was able to open his mouth again ; but it was not till the twenty-fifth day of the disease that it was possible to discontinue the remedy. The patient remained in a state of remarkable OPIUM iNEBRiETy (continued). 339 prostration and drowsiness, sleeping the twenty-four hours round, and only waking up to take his nourishment for eight days, and passed all his evacuations under him. He subsequently steadily and rapidly convalesced. The bro- mide produced no acne or other disagreeable symptoms, and certainly appeared to exert marked inhibitory influence upon the tetanus. Surely, under ordinary circumstances, no one would think of giving such extensive doses of the bromide, but liere, under the antagonizing influence of the intense reflex irritability, their effect was vastly beneficial, conducing, unquestionably, to the patient's cure. Given, as we recommend, no effect is usually produced by the bromide before the third day. From the third to the fifth, an unpleasant taste is complained of ; the bromic breath begins ; the patient is disposed to drowse, and there is a growing indisposition to muscular exertion. From the fifth to the seventh, these symptoms increase — the tongue begins to furr ; the odorous breath is marked ; the drowsi- ness deepens into sound sleep, more or less prolonged, and the inaptitude for physical exercise becomes so decided, that patients generally take to bed on the last day. The follow- ing two or three days — during the period of maximum dis- turbance from the opium withdrawal — are characterized by a persistence of the symptoms alluded to. Patient remains, more or less restlessly, in bed; general relaxation is decided; the pulse is less frequent — usually about 60 : the voice somewhat weakened ; pupils dilated ; the renal secretion augmented — though, sometimes, diminished ; the saliva increased and rather viscid, and mild hallucinations of sight and sound — almost always of sight — occur, occasionally, for tliree or four days, accompanied with a peculiar aphasic tendency, as shown by substituting one word for another — Mediterranean for Mississippi; Brown, instead of Iowa, etc. This curious symptom may occur at increasing intervals for several days. 340 DISEASES OF INEBRIETY. Dr. Clarke refers to such instances. He says: "They are hints of a distinct organ of hmguage, and suggest the notion that, inasmuch as the drug we are considering para- lyzes reflex, before it does general sensibility, language may be the expression or correlation of a peculiar reflex power." After the ninth or tenth day, the bromidial manifesta- tions gradually disappear, so that within two weeks from beginning of treatment, patient is generally up and the only prominent symptoms remaining are the debility and insomnia. Tonics, hypnotics, and vis medicatrix naturae effect speedy convalescence, and — where treatment is begun on entrance — patients are usually dismissed, cured, within a month. More than one week's employment of the sodium is not advisable lest the hallucinations become unpleasantly pei"- sistent ; and cases will present in which a minor degree of administration — five or six days — will suffice. Marked general debility contra-indicates the bromide, and a tonic course should precede it. Granted a case suitable for treatment, tliis method may- be summarized as follows : Opiate reduced, at once, to one-half or two-thirds usual quantity. Subsequent grad- ual decrease and entire withdrawal in seven or eight days. Mercurial cathartic, first night, followed by daily laxative enemas, or Hunyadi water. Bromide of sodium, 30 grain doses, increased 30 grains daily, in six or eight ounces water, on empty stomach, continued 5 to 7 days. Restlessness following opium abandonment met by hot baths, 100'' to 110°, ten to thirty minutes each, often as required. Bromide eliminated by diuretics — digitalis and nitre, and diaphoretics — hot and steam baths. Insomnia relieved by chloral, combined, if need be, with Indian hemp or hyoscyamus. Diet exclusively milk and lime- water first three days of opium abstinence. Full diet resumed soon as possible. Debility removed by generous OPIUM INEBRIETY (cONTINTJEd). 341 living, general faradization, strychnine, iron, quinine, etc., with out-of-door exercise and varied social enjo3'ment. For relief of neuralgic pain varied measures suffice. Leading the list are electricity and the local use of ether. As to the value of the galvanic current in migraine and other neuralgias, so common in opium habitues, and the manner of using it, tlie reader is referred to papers by the writer. The same agent is effective in relieving limb and lumbar pains, tliough here a much stronger current is required than can be used with safety about the head. Sometimes a faradic current acts well, and when one fails, trial should always be made with the other. Local hot baths are often of great service. Regarding the ether, those who have never used it will, we think, be surprised at its pain-easing power. In either way applied — spray, drop, or lavement — it is potent for good. These three — electricity, ether, hot water, are valued anodynes, and one special point in their favor is entire free- dom from unpleasant gastric, or other result. Other remedies relieve, at times, of the coal-tar salts, phenacetine, or phenocoll, lo to 15 gr. doses are best. It has often a hypnotic effect. A valued external anodyne is menthol, i part ; chloroform, 10 parts ; ether, 15 parts ; used as spray. Under this plan of treatment marked disorder of stomach or bowels is rare. Our rule is to give a mercurial or other cathartic at the outset, if there be alvine torpor, and then secure regular action by such laxative as seems best. If restraint be needed, large enemas of hot water may be used. Tills failing, i to 3 grs. sulpho-carbolate of zinc, 10 to 20 minim doses of fluid extract of coto, in capsules, or 40 to 60 grains of subnitrate of bismuth every four hours. If, however, it persists, the best thing is a full opiate — tinct, opii, per mouth or rectum, at bedtime, preferred. This promptly controls, gives a full night's sleep, and the trouble 342 DISEASES OF INEBRIETY. seldom returns. Fear of a bad effect on convalescence is unfounded. Diet is not restricted, unless tlie condition of stomach or bowels demands. We have again and again seen patients recover who did not vomit once, or wlio liad only two, three or four movements daily, Tlie excessive vomiting men- tioned by Levinstein and Obersteiner — abrupt disuse — we have never noted. Tiie former thought tlie collapse — which we have never seen — in several of his cases was due to vomiting and purging. More likely the largest factor in causing it was tlie exhausting mental and physical suffer- ing which his metliod entails. If the stomach rebels, entire rest for a time, or milk and lime-water, ale and beef, malted milk or bovinine, in small amount, may act well. If not, sinapisms, ether, faradism, or chloroform, alcohol and ice are of value. All failing, a full opiate hypodermic will promptly suffice. Twenty-four hours after the opiate-quitting, patients are directed to bed, and kept there two to four days, for we are convinced that rest is an aid of great value. Erlen- meyer says, "The best remedy is rest in bed. The import- ance of quiet, rest in bed, and warmth in promoting restoration during the abstinence struggle, cannot be overestimated. I order every patient to bed at the start, and can state with confidence that those who submit to this till I allow a change will get along more easily and satis- factorily during the treatment than others who do not obey, but who insist on moving about or having the run of the premises." Having thus crossed the opiate Rubicon, treatment per- tains, mainly, to the debility and insomnia. For the former, coca leads the list. Of fluid extract, 2 to 4 drachms, or cocaine, i to 2 grains, with other tonics, 3 or 4 times daily, decreasing as need lessons. As a rule, its use is ended in a fortniglit. To remove the mental and physical depression, the minor neuralgias, and the desire for stimu- OPIUM INEBKIETT (cONTINUEd). 343 lants sometimes noted nothing equals it, and full doses of tincture of capsicum often add to its value. Another agent of much service is general faradization, twenty minute stances daily. This imparts a feeling of exhilarating comfort, but care must be taken not to overdo, for a current too strong or long makes mischief, overstimu- lating and exhausting to the extent, it may be, of several days' discomfort, which nothing but time will remove. Faradism also acts kindly in easing the peculiar unrest — " fidgets " — and the nagging aches in legs during con- valescence. It may be applied in the usual way, or througli the special electrodes we have devised. Galvanism is another general tonic of value. Our method is positive pole to nape of neck and negative to epigastrium for five minutes, then the former behind tiie angle of each jaw for a minute or two, making entire stances seven to nine minutes. Another valued tonic is the cold shower-bath. With many it is a great invigorator, and patients who dread it, at first, came to appreciate it highly. Internal tonics have a place in the roborant regime. Most habitues are below par, and it is our custom to give such, from the start — phosphorus, strychnine, arsenic and quinine, combined. After the opiate-quitting, coca, in some form, can be added. If anaemic, ferri tincture, or Blancard's pills. Caffein is of value. It is stimulant, tonic and diuretic. We sometimes give it with codeine and cocaine. Digitalis is often useful. In some cases, cod- liver oil is of service — with pepsine and quinine, with malt, with phosphates, or plain — and may be given for months. Some anorexia is usually present, yet it may not prevent the regular meal, and need never occasion anxiety, for it will likely give place to a vigorous appetite, whicli may be encouraged to fullest feeding siiort of digestive disaster. If it be slow in returning, half grain doses of cannabis, an hour before meals, often have a marked action. 344: DISEASES OF INEBRIETY. Regarding the insomnia, Levinstein said : " Sleepless- ness, which is generally protracted up into the fourth week, is very distressing." Our record differs. Wakefulness is an invariable sequel, but usually not so marked nor pro- longed, and in ordinary cases recovery can generally be promised, without the loss of a single entire night's sleep. We have known a patient able to dispense with hypnotics in five, others in eight, and the average, in a series of cases, was eleven nights. The insomnia is of two kinds. Most patients secure sleep on retiring, but waken early — 3 or 4 o'clock — and fail to get more. Others remain awake nearly all night before slumber comes, and these usually require soporifics the longer. For relief of this, cannabis indica will often suffice. The hemp is given in 40- to 60-minim doses, in capsules, or mixed with glycerin, or ginger syrup, two hours before bed- time. There may be noted, in some, laughing and talking during the first hour, tending to sleep in the second. Many require nothing else. At the end of a week it is less- ened, and usually, ended in ten or twelve days. Other hypnotics — chloral, chloralamid, trional, sulfonal, paraldehyde, hypnal — in full doses, often work well. Chloral, during the first 5 or 6 nights of opium abstin- ence, fails as a soporific, often causing a peculiar excite- ment or intoxication — patients talking, getting out of bed and wandering about the room — followed after several hours, by partial sleep. Later, in full doses — we prefer 40 grains at once, rather than two 20 grain doses — alone, or with a bromide, it can be relied on. If, as rarely happens, the sleepless state is so pronounced or prolonged as to distress patient, we never hesitate to give a full opiate, by mouth, and with good result. Erlen- meyer says: "In such cases there remains nothing to do but to resort to morphine. I give, then, the alkaloid inter- nally on two consecutive evenings ; a certain cumulative effect takes place. The first night in the dose of Yi grain, OPIUM INEBRIETY (cONTINUEd). 345 there is usually no sleep ; but on the second night, after giving the same dose, a sound sleep of six hours' will ensue. I have not observed any special danger from these resumed doses of morphine, although I feared it ; but after I was constrained in several bad cases, when every other medicine had failed, to resort to this, I was convinced that my fear was groundless." In all cases drugs should be dropped as soon as pos- sible, and sleep secured by a walk or other exercise — an electric seance, a Turkish or half-hour's warm bath, a light meal, a glass or two of hot milk, one or more of these before retiring. Patients, whose slumber ends early, often note a peculiar depression on waking, and if so, a lunch, hot milk, cocoa, coffee, beef, or bovinine should be at com- mand. It may be well in passing to refer to certain minor sequelae and their treatment. If dyspnoea or palpitation, a stimulant — coca with capsicum or Hoffman's anodyne with aromatic spirits of ammonia — will promptly control. If aching pains in the calves, strong galvanic or faradic currents, hot water, massages, or ether will relieve. If a peculiar burning in soles, mustardized foot-baths. If marked hysteria, ether inhalations. Belly pain may be eased by hot fomentations, or full doses of ether in hot water, or camphor with capsicum. The latter, with atropine injection, act happily in ovarian irritation. Very seldom unrest and insomnia compel hyoscine. If so, hydrobromate i-ioo to 1-20 grain, hypodermically, or, double, by mouth. CHAPTER XXXIII. ETHER INEBRIETY — ITS HISTORY AND PROGRESS. Ireland has in the nineteentli century presented to the world two interesting and remarkable series of inobrio- psycliological piienomena. In 1838, a simple-minded Roman Catliolic priest, Fatiier Matliew, adopted and be- gan to advocate the practice of abstinence from all intoxi- cating drinks. So amazing was the impression made by him that, in three years, the roll of the teetotal pledges which he had administered exceeded 5,000,000, in Ireland, in aiddition to large numbers in England, Scotland and America. The reality of this epidemic of temperance was attested by the statement of the Chief Secretary, in 1840, that "the duties of the military and police in Ireland are now almost entirely confined to keeping the ground clear for the operation of Father Mathew." Though this great wave of sobriety has gradually receded, till now the extent of drinking in Erin is simply terrible, I am every now and again meeting professionally with sons and daughters of Hibernia, who glory in their steadfastness to the pledge which they so long ago took at the hands of the Irish apostle of temperance. An accurate study of this unique crusade would, in psychological results, amply repay the labors of any earnest student of mental science. Curious to relate, the other series of inebrio-psychologi- cal phenomena is an experience in an opposite direction — an experiment, so to speak, not, as in the former case, in tem- perance, but in intemperance. 347 348 DISEASES OF INEBRIETY. The disease of inebriety or narcomania (a mania for intoxication by any kind of narcotic or anaesthetic), may besides other phases, assume a form correspondent to the particular inebriating substance. It may, therefore, be interesting to glance at the origin and growth of this new mode of inebriate indulgence, as this is the first opportu- nity afforded to us of observing the rise and progress of such a process in a community. The centre from which etlier drinking spread was the town of Draperstown (with a population of some 300), in the southern part of the County of Londonderry. Before Father Mathew's abstinence propaganda, etiier drinking was there unknown. Between 1842 and 1845 a local medical practi- tioner, in response to a request from a few newly-pledged abstaining converts for something tlie taking of which would not violate their vow, gave them a drachm of ether in water. So far as I can ascertain, this was the /o/is et origo viali. A desire for more frequent doses grew upon the ether drink- ers, and the practice spread in and around Draperstown till there was a shop for the sale of ether, in one town, to every twenty-three of the population. In the session of 1855-6, an Act was passed by the British Legislature allowing spirits of wine to be used dutv-free in arts and manufactures provided it was made nasty as a drink (which the Govern- ment, in their innocence, supposed would prevent people from drinking it) by the addition of a minimum 1-9 of methy- lated spirit. As ether prepared in this way is much cheaper than ordinary sulphuric ether, this cheap production of "methylated ether " caused the consumption to increase ** by leaps and bounds." The present ether area was, from its mountainous fea- tures, a central locality for the illicit distillation of whiskey. Owing to the activity of the police and the making of roads, this illicit traffic was effectually stamped out. The disap- pointed cheap whiskey drinkers found a cheap unintoxicant in ether. Mr. H. N. Draper first called attention to Irish ETHER INEBRIETY. 349 ether drinking in 1877, followed by Dr. B, W. Richardson, about 1879, and by Mr. Ernest Hart in 1890. Ether drinking was in a year or so gradually introduced from Draperstown into the neighboring town of Mtighera, and soon extended its sway till it occupied an area of some- where about 295 square miles, with a population of nearly 79,000 souls. This area may, in general terms, be said to comprise the mountainous districts, especially of Derry and Tyrone, and to some extent, of Armagh and Antrim. Cases of ether intoxication have occurred in Dublin and ottier parts of Ireland, in Glasgow (Scotland), in Lincoln- shire in England, and I have seen several in London. All the cases which I have seen in England have been persons of education and refinement, who had first been al- cholic inebriates and gradually developed into devotees of these twin poisons. Nearly all of these English cases have been females, the only males having been members of the medical profession. In Ireland, women assert the equality of the sexes by taking their fair share of this form of intem- perance. Small farmers and agricultural laborers make up the bulk of the Irish ether tipplers. Workmen, too, are well to the front. But the practice is by no means confined to these classes. Members of the learned professions have their representatives. Etherists are to be found at almost all ages from puberty onwards. Sturdy Irish lads and beautiful Irish lasses, brimful of Hibernian wit, as well as "60-year olds" of both sexes, are slaves to ether drunken- ness. The mother may be seen with her daughters, and maybe a neighboring Irishwoman or two, at a friendly ether " bee." The habit has become so general that small shop- keepers treat the children who have been sent to purchase some article, with a small dose of ether, and schoolmasters have detected ether on the breaths of children from 10 to 14 (or even younger), on their arrival at school. Some critics have endeavored to lay the blame of this new development of inebriety on the Roman Catholic 350 DISEASES OF INEBRIETY. religion. Nothing could be more unwarrantable and unfair. The disease has spread principally among Roman Catholics, simply because this is the creed of the greater part of the population. One Protestant village, Tobermore is as bad as any other place. All my cases have been Prot- estants. The amount swallowed at a draught varies mainly with the stage of education in ether consumption. A novice will find a drachm (a teaspoonful) sufficient. Gradually the wished-for effect demands an increased dose, till X of an oz. may in time become the ordinary "peg" of an accomplished drinker, to use the phraseology of Anglo- Indians. These are average quantities of a so-call5d "moderate" drinker. More ''seasoned casks" have a higher capacity, many toping off a half a wineglassful as unconcernedly as an average Englishman would drink a glass of claret, or an average American a glass of cham- pagne. The amount of ether consumed in a day is often remark- able. A confirmed ether inebriate will take a much larger dose than any I have just enumerated, and repeat the dose three, four, five, or even six times in the twenty-four hours, when " on the spree." Indeed, in some cases, half a pint has been the regular daily allowance of constant (or habit- ual) inebriates. In England I have known an ether inebri- ate use a pint of ether by inhalation every day. In Ireland, many persons keep themselves intoxicated pretty well dur- ing the day for the sum of sixpence — taking two penny- worth at lo o'clock, I o'clock and 4 o'clock. What a para- dise for drunkards ! Drunk three times a day for 13 cents ! In England, in my own practice, the majority of ether drinkers have inhaled the poison. In Ireland the universal method is drinking. By the latter mode the ether is taken "neat." Owing to an idea that ether, like whiskey or brandy, should be drunk diluted with water to sheathe the ETHEK INEBRIETY. 351 virulence of the poison, the uninitiated and ignorant Eng- lisliman, when in Ireland, sometimes mixes his ether " peg" with water, "just to try the stuff, you know." Ludicrous failure awaits him, for, unlike ardent spirits, ether is but sparingly soluble in water. The pungency of ether, except to those who have "finished their education," generally calls for an "overture" to the "act" of ether swallowing. Scene I. — The mouth is washed out with cold water. Scene II. — A draught of cold water is drunk. Scene III. — The ether is swallowed " neat." Scene IV. — The perform- ance closes with a second and final drink of cold water. The preliminary draughts of water are to cool the mouth and throat, and the post-ether draught is " to keep the ether from rising." The washing of the mouth is soon omitted. By-and-by the preliminary draught of water follows the same fate, the ether dose and the succeeding draught of water being the commonest method. As his education advances, the etherist dispenses with water alto- gether. He may for a while, especially when drinking an unusually large dose, hold his nose with one hand, but probably ends by despising all precautionary safeguards, and by simply drinking his mouthful of ether at a gulp. Ether purus of the British Pharmacopoeia was at one time affected by my inebriate patients. This pure ether (02^15)20, which is free from alcohol and water, has been in my hands the only ether preparation which has proved tO' be without complicatory drawbacks when used as an anaesthetic (Brit. Pharmacopoeia, 720 ; U. S., 725). Ether of the B. P. (sulphuric ether) was, however, the article gen- erally used for purposes of intoxication. It contains 8 per cent, of alcohol and water with 92 per cent, of ether purus ^ and is soluble in all proportions with rectified spirit, but in only I in 10 with water. The specific gravity should be (B. P.) .735 ; (U. S.) .750. It is a swift, potent, diffusible stimulant, narcotic, anaesthetic and antispasmodic, of great 352 DISEASES OF INEBRIETY. value in medicine. It has a strong, penetrating odor, is sweetish, hot, burning and pungent to the palate. To America the whole world owes a deep debt of grati- tude for ^he introduction of ether as an anaesthetic by Dr. Morton, in Boston, in 1846, and any saddening misuse of this grand mode of alleviatiug human suffering ought not to lessen our appreciation of tliis splendid boon to humanity. By the Act 18 and 19 Vict., the use of spirit of wine, free of duty, was permitted in the arts and manufactures, on the addition of a minimum of 1-9 of wood-naphtha (methylic alcohol or spirit from the destructive distillation of wood, after rectification ; specific gravity .803 B. P.) with a view to prevent this fouled liquid from being drunk as a bever- age. Ether prepared from this fouled duty-free spirit is, of course, much cheaper than ether prepared from spirit of wine on which duty has to be paid. Tlie intention, how- ever, was defeated, inasmuch as in the process of manufac- ture of ether from the fouled spirit, the fouling ingredients (/. e., the methyl products) are destroyed. Thus, contrary to tlie general belief in what is commonly called "methyl- ated ether" being as nasty as the methylated spirit which is used for lamps and for polishing purposes, " methylated ether" is to the taste hardly discernible from pure sulphuric ether. This so-called " methylated ether " is practically undistinguishable from ether (B. P.) at the specific gravity of .717, /. ^., when purified. At any other specific gravit}'^, an odor is given off after evaporation. Practically, one cannot discriminate between the ethylic and methylic productions. Price. — The ether thus prepared from the duty-free spirit (sp. vin. rect. cum methylic alcohol), can be produced at as low as one-seventh of the cost of ether prepared from the duty-paid spirit, the latter being bought wholesale at $1.25 per lb., and the former at as low as 16 cents. Ether is imported mostly from England, partly from Scotland, by larger chemists and druggists in the principal towns of Cookstown, Magherafelt, and Maghera. The ETHER INEBKIETY. 353 large dealers supply small shopkeepers, and also cottagers, who sell in "drauglits " (rather less than 2 teaspooiifuls) for one penny. Tlie small shopkeepers also supply the hawkers (who are very often women), who attend fairs and other festive gatherings to dispense the "draughts" of the liquid poison. These "draughts" are also to be had from the surgeries of some medical practitioners, and in cottages or ether shebeen, where the cottager keeps a pig or two, and sells ether, the country people frequently giving potatoes, meal, or other produce in exchange. Tlie hawkers carry about a bottle of ether, and do not scruple at selling to any one, however young, bartering a little for one or two eggs. In this way the children may procure the ether on their way to scliool. Intoxication by ether presents one distinguishing feature as compared with alcoholic intoxication. Tlie phenomena are practically alike, but in rapidity of manifestation, alcoiiol is " nowhere." Indeed, in this respect, ether beats the record. There is the exhilarative stage of morbid exalta- tion, when the fun and exuberant merriment, the latent and ineradicable impulse of one " spoiling for a fight " of the genuine Irishman stands revealed in the twinkle of the eye, and the flourish of the shillelagh. The pleasing but quickly vanishing whirl of enjoyment is followed by an evanescent episode of brain disturbance and mental riot, with muscular paralysis and incoordination. To these succeeds the concluding comatose stage, when the patient is said to be " dead drunk." The shortest period in which I have seen this inebriate panorama move on till it swung round to recovered sobriety has, with alcohol, been six hours. With ether, I have witnessed the entire revolution in less than two hours. In my observation an alcoholic inebriate career, from start to a fatal finish, has in America been, on an average, one-third of the duration of a corresponding career in Britain. So, curious to say, has the length of an ether 354 DISEASES OF INEBRIETY. intoxicative paroxysm been one-third the length of an alcoholic intoxicative paroxysm. Thus the etherist can have three thorough "drunks "for one of the alcoholist. Herein, in addition to the greater cheapness, lies the supe- rior claim of ether to the " greedy for intoxication," the true " narcomaniac." Intoxication by ether may be described as "hysterical," and intoxication by ether ^«;;/ alcohol as "maniacal." A man arrested while drunk on ether alone, would probably be quite sober by the time the constable had him at the police station, which might be very awkward for the con- stable, though the arrest had been made when the man was in a frenzy of boisterous excitement. Several deaths from ether, and ether cunt alcohol, have occurred. Little is known of the pathology of ether. The habit has been too young to afford opportunities of much post- mortem examination of ether inebriates. Premature old age, an antedated shriveling up of the living frame, attests the poisonous influence of the destroying agent. Gastritis (acute and chronic), debility, dyspeptic distress, epigastric pain, pallors, tremors, timidity, moroseness, suspicion, nerv- ous prostration, chilliness, a cyanosed or lemon skin, and an intermitting heart-beat, with exaggerated reflexes, are prominent symptoms. I have one such victim in my mind's eye now. Fawning, cunning, terror-stricken, this wretched medical colleague is the incarnation of utter misery. Not yet 40 years of age, he shuffles about like a worn-out old man of 90 after a wasted and mis-spent life. It has been urged by some medical authorities that ether is guiltless of producing any pathological lesion, from the almost light- ning rapidity with which its inebriating manifestations appear and fade away, and from no serious morbid after- death appearances having been observed. This conclusion is, in my judgment, premature. Judg- ing from the symptoms from which I have seen ether inebriates suffer, I have not the slightest doubt that ether ETHEK INEBRIETY. 355 has a pathological influence on various organs and tissues, and that, if ether drinking could boast of as venerable an antiquity as alcohol drinking, unmistakable lesions would have been but too manifest. Wliat are the forty years of ether consumption by a hundred thousand persons, to the thousands of years of alcohol consumption by at least as many millions of human beings ? Happily, this new form of inebriation is but in its infancy, so there is some hope that its growth may be " nipped in the bud." As, in the conversion of methylated spirit into ether, the nauseous methyl products are destroyed, something might be done towards making the liquor loathsome to the palate by the compulsory addition of the wood spirit after the completion of the etherification before the sale of the liquid. This, however, would be but a palliative, for I have had patients under my care who drank methylated spirit (some even from jars with anatom- ical preparations) and in Edinburgh and Glasgow, Sun- day drinking of tiiis nasty beverage recently flourished apace. In a certain locality in the north of Ireland, the drinking of methylated spirit was introduced seven or eight years ago. At first confined to the very poor in a hilly district, it has spread rapidly, till now farm laborers and farmers are daily indulging in it, Tliere are many inebriates who hate and abhor the taste of the intoxicant which, in their narcomaniac madness, they would barter their salvation to procure. Another remedy would be the abolition of the retail sale. This would help by putting difficulties in the way of the drinker, but would only mitigate the mischief. Still more effectual would be the scheduling of ether as a poison, the sale of which is restricted to druggists under certain safeguards. This course was so readily adopted for Ireland by the British government in January last, that I have j'et hope the dav will come when the more deadly allied poi- son — alcohol — will be placed in the same category, and so 356 DISEASES OF INEBRIETY. dangerous a drug vviVl be relegated to the shelf of the apothecar}'', its sale hedged in with as stringent precautions as is now the sale of arsenic or prussic acid. But tliis hal- cyon era of prohibition will only be attained after a pro- longed struggle, amid the howls and groans of an enraged liquordom, whose indignation is concentrated on all who attempt to " rob a poor man of his beer."' It is too soon yet to foretell the ultimate result of the bold step taken by our Government in scheduling ether as a poison, but it has made the procuring of ether for drink- ing purposes so difficult that for the present the sale lias diminished by at least 75 per cent. I fear, however, that the cupidity of some wlioiesale dealers will incite them to risk the penalties of the law by surreptitious sales, which will speedily be ferreted out by the marvelous cunning of the diseased and demoralized inebriate. The lines of sound treatment of ether inebriety, and of its prevention by law, must alike be based on an intelligent appreciation of the true character and etiology of ether drunkenness. This is, in reality, but a new manifestation of an underlying morbid condition which renders certain of the sons and daughters of men peculiarly liable to plunge into intoxication. We can never hope to succeed in the cure and prevention of any disease, until we first recognize the presence of tiie disease itself. The malady of narcoma- nia, as subtle as it is far-reaching in its influence on body, brain and mind, and morals, is a legitimate outcome of natural law, and we will not be adequately equipped for the fight till we are thoroughly conversant with the laws under which every form of the disease of inebriety is developed and propagated. CHAPTER XXXIV. COCAINE INEBRIETY. The dangers to be apprehended from the abuse of cocaine are probably hardly yet quite realized, at least in this country. A great deal of harm has undoubtedly been done of recent years by the use of cocaine as a help to break off the morphia habit. An exaggerated estimate of the assist- ance to be obtained from the former drug has been formed by such writers as Freund, and although Elwin and Erlen- meyer have warned us not to fly from Scylla to Charybdis, still it is to be feared that the notion lingers that cocaine may be used advantageously and safely for this purpose. Nothing can be more mistaken. Cocaine is more seductive than morphia. It fastens upon its victim more rapidly, and its hold is, at least, as tight. Cocaine solutions are probably somewhat too freely prescribed in cases of diseases of the nose and naso-pharynx. Patients who use the drug in this way become very soon acquainted with its agreeable effects. Several cases have been recorded by American authors of cocaine habit arising thus. That cocaine has not been even more extensively misused is probably due to its being still a comparatively new drug, and also in part to its costliness. Up to the present time the largest number of its victims appear, unfortunately, to have been medical men. Cocaine owes its special dangers to three causes. First, it is particularly treacherous. Secondly, it produces early mental breakdown both in the moral and intellectual spheres. Thirdly, it is intensely toxic, bringing about destructive tis- 357 358 DISEASES OF INEBRIETY. sue clianges after a comparatively short period of abuse. Taking the last first, we know tliat aicoliolic poisoning is usually a slow process, while morphia may be taken even in very large quantities for years without producing any serious structural changes in the nerves. In fact,' we recognize no distinct pathological results of morphia poisoning. On the other hand, the marasmus of chronic cocaine poisoning, appearing early and developing with extreme rapidity, is but one indication of the serious organic changes that are produced. Convulsions similar, as Richet points out, to those of cortical epilepsy, have been noted in a great number of cases. In at least one recorded case, death occurred in an epileptiform attack. In animals, poisoned with cocaine, remarkable rise of temperature has been observed by Mosso Reichert and otiiers. Acute poisoning in animals kills by asphyxia ; clironic poisoning, as Zanclievski shows, is accom- panied by albuminous degeneration of the ganglionic cells in the medulla oblongata and spinal cord, as well as of the nerve cells of the heart ganglia and of the liver cells. In other more advanced cases this author has found atrophic changes with vacuolation in the cells of the medulla and cord, fatty degeneration of the muscular fibres of the heart, and atrophy of the liver cells. Degenerative changes also occurred in the arterial coats, particularly in the spinal cord Perhaps organic changes similar, but less in degree, account for the slowness and difficulty in recovering from the cocaine habit, and the liability to dangerous collapse which exists during the process of withdrawing the drug. The treacherous and insidious character of cocaine results from the fact that when taken in small doses it pro- duces at first apparently nothing but a slight degree of ex- altation, a sense of well being, a feeling of mutual and bodily activity, of general satisfaction and of good humor that is most agreeable. There is no mental confusion which the consumer of cocaine is conscious of, and the only overt symptoms he betrays at this stage is more than natural COCAINE INEBRIETY. 359 talkativeness. The hypnotic effects, when they appear, are not overwhelming, and there is no headache, no nausea, no confusion next day. This cocaine is probably the most agreeable of all narcotics, therefore the most dangerous and alluring. It is to be feared that these peculiar qualities may, indeed, conduce to raise this drug in the future to the bad eminence of being as Erlenmeyer says, the third great scourge of the human race (alcohol and opium being the first and second). Like several other observers, I have sat- isfied myself by experiments on healthy persons, that the agreeable results described actually follow the ingestion of small doses of cocaine, and this fact impresses one strongly with the feeling of how seductive this drug would be to the neurotic or debilitated. Of course, as is the case with all narcotics, small doses soon lose their effect, and hence a rapid increase is necessary. The rapidity with which mental symptoms of a grave character appear is remarkable in cases in which increasing quantities of cocaine are taken. Within three months marked indications of degeneration, loss of memory, hallu- cinations, and suspicion deepening into persecutory delusions have been found. The following is a characteristic clinical picture : on the one side in the cachexia or bodily ruin, on the other side in the moral impairment and pronounced mental affection. Patients who use cocaine alone — and those who have endeav- ored to wean themselves from morphine by its aid, and so added cocainism to the morphine habit — appear marasmatic. The skin is of a pale yellowish, almost cadaveric tint and withered feel ; the extremities are cool and covered with cold sweat. The eyes are deeply sunken, glistening, and surrounded by a dark ring ; the pupils widely dilated. Appetite is lost ; digestion disturbed. Salivation with dry- ness of throat may be complained of, and further, partial sensory disturbances or total analgesia. From the paralyz- ing action of cocaine upon the blood-vessels, patients com- 360 DISEASES OF INEBKIETY. plain of palpitation and breathlessness, troublesome sweat- ing and noises in the ears, and also syncopal attacks and dyspnoea. The pulse is more frequent and easily compres- sible. They suffer from a want which must be satisfied ; they become nervous, trembling, and fall into a wretched condition of neurasthenia. Speech is disconnected and can scarcely be understood ; impotence and incontinence of urine may appear. Sleep- lessness sets in early. One of the most characteristic effects of this habit is the occurrence of muscular twitching, tonic and clonic convulsions, and finally epileptic attacks in which the patient may die. The mental symptoms may take the form of hallucinations, usually of general sensa- tion, but not infrequently of sight as well. General mental weakness may set in rather early, to be observed in a loss of memory and unusual prolixity in conversation and corres- pondence. When the drug is withdrawn, besides the vaso- motor symptoms there may be seen depression, impairment of will-power, weeping, etc. The chronic form does not protect from acute intoxication. The treatment of a cocaine inebriate is practically the same as that of opium and alcohol cases. There is a degree of brain-degeneration apparent in the morbid impulses and strange, uncertain mental action of these cases that approaches very near to insanity. Abrupt withdrawal of the drug is the safest plan, and reliance is to be placed on bromides, foods, and baths to relieve the irritation and depression which follow. In the method of gradual with- drawal it has been found that small doses may result in collapse. In one case, in which lo grains a day had been previously taken, and by gradual withdrawal the amount had reached 3 grains, symptoms of heart failure and paral- ysis suddenly came on. The dose was increased and the patient recovered. In another case, complicated with alcoholism, the daily allowance of 7 grains was reduced to 4, when a violent collapse set in, which was cliecked by giv- COCAINE INEBRIETY. 361 ing the usual dose. The case finally became an alcoholic, but eventually recovered. The treatment of these mixed cases requires great care and watching, as they are especially liable to fatal collapse or to develop some form of acute brain disease. Strychnine and the mineral acids are useful. Because of its rapid stimulant action strychnine, given hypodermi- cally, 1-40 grain every three hours, will often prevent col- lapse when the cocaine is withdrawn. Mineral acids, chiefly phosphoric, may be given in i drachm doses three times a day as a general tonic, unless contraindicated by an acid stomach. In these cases mental conditions approaching delirium are present. The functional disturbance of the heart and the emotional changes that are so prominent in the latest stages, and the uncertain co-ordination of both the higiier and lower brain and nerve-centres, all indicate the most serious disturbance. Some of the forms of iron, quinine, and strychnine may be very useful at the beginning of the treatment. Water containing bromide of sodium, 40 grains to the ounce, and charged with gas, can be given freely for some time with good results. The therapeutics must be governed by the conditions of the case. AH cases should be treated in an asylum, wliere the physician can have the full control of the conditions and surroundings of the patient. Home treatment is dififi- cultand unsatisfactory. The patient is always hypersensitive to pain and suffering, and will use deception and intrigue t© avoid it. The will-power is of no assistance, and the success of treatment will depend on accurate study and observation of the case. Drugs are of little value ; foods and hygienic care, including baths, will give the best results. In all chronic drug-maniacs the pliysician should be on the lookout for cocainism. When cocainism is present a sudden addiction to opium, alcohol, chloral, or chloroform may arise, and in all cases the piiysician should be prepared for a sudden fatal termination of the case at anv time. CHAPTER XXXV. CHLOROFORM INEBRIETY. The following history of a case is so graphic and full of suggestions as to give the reader a good idea of sucli cases. He says : "With me the chloroform infatuation was a case of love at first sight. I had been always temperate, almost a total abstainer from stimulants of all kinds. Once or twice I had smelled chloroform, and thougiit its odor pleasant. I was a young man just finishing my education, and fond of study. I had had some curiosity to know what it was like to be put to sleep with chloroform, and one night I happened to see a one-ounce bottle of chloroform wiiich was bought for the toothaciie. I took the bottle home with me, and when I went to bed put a little of the chloroform on a handkerchief, and for the first time felt the deligiitful sensation of being wafted through an enchanted land into Nirvana. Those wiio know nothing of intoxication, except in the vulgar form produced by whiskey, have yet to learn what power there can be in a poison to create in a moment an Elysium of deligiit. It is a heaven of chaste pleasures. What I most remember is the vivid pictures that would seem to pass before my eyes — creations of marvelous beauty — every image distinct in outline, perfect in symmetry, and brilliant in coloring. The enjoyment is purely passive ; you have only to watch vision after vision ; but why each vision seems more wonderful and charming than the last you can- not tell, and you do not stop to question. "I suppose that it was an unfortunate circumstance for me that I had never been drunk before in my life, and I 363 364: DISEASES OF INEBRIETY. never thought of comparing my blissful condition with that of the wretches I had sometimes seen staggering through the streets. I liad made a great discovery. I iiad found a golden gate into dreamland — dangerous indeed to approach, I knew that, but who would heed any danger where the prize to be obtained was so great ? — and guarding jealously my secret, I took care night after night to have by me the key to tliat golden gate. Probably I inhaled from half a drachm to a drachm or two each time. Generally I did not waken again until morning, and my sleep seemed to be just as refreshing as usual, only now and then I would wake with a trifling headache and feel disposed to lie a little longer in bed than common. My bodily condition did not seem to sufier in the least, and my faculties all seemed as keen as ever. I felt no craving for my pet intoxicant during the day — did not give it a thought often until bed-time came, and then it would occur to me for a moment to try and see how it would seem to go to sleep in the ordinary way, the conclusion always being that — to-morrow night I would make the experiment. So, before I knew it, I was a slave. I would say to myself, ' It does not hurt me ; it seems to have no more effect than the cigar my friend smokes after dinner. Really I believe it is a positive benefit. It seems to keep my bowels regular, and it certainly makes me sleep soundly all night.' "But after a while I found that I was using a larger quantity of chloroform than at first. I would take a two ounce bottle half-full of the stuff to bed with me, and inhal- ing directly from the bottle would forget at last to cork it, and in the morning it would be empty. Sometimes I would wake after midnight, or partially wake, to take another dose. I found that there was a bad taste in my mouth all the time, keeping me in mind of chloroform. I was often nauseated in the morning, and sometimes at intervals dur- ing the day. I began to feel a longing for chloroform whenever I had a little headache, or was dispirited from CHLOEOFOKM INEBEIETT. 365' any cause, and I sometimes yielded to what I already knew was a morbid craving. I began to be indifferent to the things that personally had interested me, avoided society, and became depressed in spirits. My complexion became sallow, whites of the eyes yellow, the bowels sometimes windy and unnaturally loose, skin dry and seemingly bloodless, and injuries of the skin did not heal rapidly. In winter there was a tendency to chapping, that had not before been noticed, " Meanwhile I had ceased to have visions, or they came rarely. I began to realize that my pet habit was becoming my tyrannical master. I had no special cares to drown, but it became my insane pleasure to draw over my senses the veil of oblivion. I loved the valley of the shadow of death. I knew there was danger that some night I should pass over the line, into a sleep from which there would be no waking ; but death had no terrors for me. Nay, to bring all my faculties and powers and ambitions into tlie sweet oblivion of transient death was the one pleasure for which I cared to live. I was conscious of a profound moral deterioration ; I became materialist ; I had no soul ; immortality was a dream of the ignorant ; I, who had a thousand times anni- hilated my own soul with my senses, knew that the dream had no corresponding reality. ** Yet all this time I continued faithful in my daily duties, and resisted successfully the temptation to hurry through my evening so as to get the sooner to my chloroform, I did not admit to myself that I was a slave to the habit, or even that the habit was an injury to me, as yet ; but I began to be afraid, and the more when I found, when I resolved (as often I did), to omit my nightly indulgence, just for a week, how impotent my will was in the matter, "This was my condition at the end of two years. I was still only using a moderate quantity of chloroform, about three drachms daily, exceeding that quantity only by acci- dent. An opportunity offered for a change of occupation 366 DISEASES OF INEBRIETY. and surroundings, which I eagerly seized in the hope that it might enable me to break my fetters. For about three months, under the new surroundings, I abstained from chloroform, and found it really not difficult to do so. I began to think that I had greatly over-rated the power of the habit. At all events, after the first week I had no crav- ing for the stimulant. But one day I came across a bottle of chloroform. When I saw it I smiled to myself to think that I had imagined myself a slave of any such thing. Night came, and when I was ready for bed the devil of appetite gave me his commands, and I obeyed. Just one smell to see whether I really wanted it ; I would not take the bottle to bed with me. So I inhaled, standing, directly from the bottle — a full pound of chloroform — and with the first breath of the vapor came back, with renewed force, all the old appetite, keener than ever from long abstinence. Once more I saw the old-time visions, as beautiful and as vivid as at first. One peculiarity of these visions I may speak of right here. Objects would appear with wonderful sharpness of outline just as they would be seen with the eyes, only reduced to micoscopic size like objects seen through an inverted microscope. "To go on with my story. What happened after I got the bottle in my hands I do not know. The next morning I found the bottle corked and in its place, but only half full of chloroform, and I was told that I had been lying in some kind of a fit ; some thought I was drunk — as indeed I was. From this time I realized myself a slave, but not now a willing one. I did not again commence at once the use of the chloroform, but at intervals of from three to eight weeks would indulge in a regular spree, lasting from one to three days, during which I would keep myself as nearly as possible dead drunk, and would consume from four to eight ounces of chloroform. All this time I kept my habit a secret, and continued to do my ordinary work CHLOKOFOKM INEBRIETY. 367 with the usual zest in the intervals between my sprees. At last discover)^ came. You well remember how I was found apparently lifeless, and how by the active use of restora- tives you brought me to myself. How my moral percep- tions were quickened the moment I saw myself througli the eyes of another ! " You know that it was not in a week or a year that I was placed morally on a firm foothold again. Indeed, you did not know how often, after I had given you and myself my word and pledge to abstain wholly from chloroform, I relapsed, taken unawares by the tempter. For more than two years I kept up the conflict, too often thinking the final victory won, only to find there was one imperative command it was useless for me to attempt to disobey, and that com- mand came to me whenever the least whiff of chloroform entered my nostrils. Once or twice I tried tlie expedient of returning to my first practice of a regular moderate use of the stimulant, but I found that moderation was now almost impossible, if I went to sleep under the influence I would awake again, and find myself then unable to sleep, distress- ingly wide awake and nervous, until I courted again my 'dearest foe.' Symptoms like those of delirium tremens several times developed. I saw ' things,' not now beautiful visions, but shadowy images, that filled me with nameless, irrational horror. Appetite was capricious. I was fre- quently nauseated, but food seemed to relieve this condi- tion ; vitality was low, the blood ran sluggishly in my veins, and seemed especially to desert the surface of the body. I suffered particularly in cold weather, and it was during cold weather in winter, especially, that I found it almost impos- s-ible to resist my besetting temptation. "At last I prevailed by sheer force of will. I had recov- ered enough faith in the soul to assert my freedom, and I now look back upon those years of conflict with a kind of self-pity, to think I could have been so weak. But I do not to-day court temptation. I am not conscious of a lurking 368 DISEASES OF INEBRIETY. appetite, but I dare not put my virtue to any severe test. -I am sure, however, that the chloroform habit is one that can be broken by steady determination. I have no faith in any process of tapering off. It is just as easy to quit once for all as to prolong the agony, and the suffering is often purely imaginary. It took many months for me to recover. If doctors only knew the fascination of this drug, they would seldom or never prescribe it. The danger of the wine cup is nothing to that of the chloroform bottle." CHAPTER XXXVI. COFFEE AND TEA INEBRIETY AND THEIR EFFECTS. Most physicians are doubtless able to recall numerous instances in which coffee has induced more or less serious symptoms. It seems that personal idiosyncrasies often determine the extent of the evil. The evils upon the eyes and ears of people are more frequent from coffee than from tobacco or alcohol. It does not absolutely destroy vision or hearing, but it induces functional troubles very annoying to their possessors. That coffee is the efficient agent appears from the fact that upon the entire discontinuance of the use of coffee, the symptoms complained of disappear. Dr. Guelliot has published twenty-three cases of chronic caffeism. Of these cases seventeen were women. The following are the principal symptoms : Anorexia, disturbance of sleep, trembling of the lips and tongue, attacks of gastralgia, different kinds of neuralgia, dyspepsia, and leucorrhoea, often profuse. In the twenty- three cases, he found in eighteen, anorexia ; in sixteen, disturbance of sleep ; in sixteen, trembling of the lips and tongue ; in twelve, leucorrhoea ; in eleven, gastralgia ; in ten, dyspepsia ; in ten, neuralgia of various forms ; in eight, cephalalgia ; in four, vertigo and convulsive attacks ; in four, obstinate constipation ; and in three, constipation and diarrhoea alternating. The patients had pinched, pale, wrinkled faces, a weak, rapid pulse, and the sleep was disturbed by anxious dreams. The following is the account of a typical case : A woman 369 370 DISEASES OF INEBRIETY. in middle life kept her pocket full of coffee, which she ate constantly. Her skin was of an earthy tint, constipation was obstinate, sleep very irregular, and her mind restless, anxious, and full of forebodings. She wasmucli emaciated, and both the nervous system and digestion suffered severely at times. The lips and tongue were tremulous, dry, red, and cracked. The appetite was very irregular, and vertigo, prolonged headache, and epigastric pain were present most of the time. She was placed under treatment and became delirious. Beef-tea, milk, baths, and a mild galvanic current were used for several weeks, and these were followed by bark tonics. She was discharged restored six months later. The evil effects of coffee are especially observable in children. Tlie coffee drunkard is described as thin, pinched features, pale, wrinkled face, and a grayish yellow complex- ion. The pulse is weak, frequent, and compressible. The sleep is troubled with anxious dreams. Although coffee does on the whole far more good than evil, it is important to bear in mind the evils that it is able to produce under favoring circumstances. In a general way it may be said that indoor brain workers do not bear coffee as well as outdoor muscle workers. Persons of nervous temperament bear coffee badly. The effects of coffee when pushed to an excess may be to some extent confused by the alcohol and tobacco which often accompany it, but they can be studied more accurately in women, especially in those who do not drink coffee, but eat it. As a rule both nervous system and digestion suffer in these cases. The appetite fails, there are attacks of sliarp epigastric pain, much vertigo, and prolonged headache. There is less insomnia than might be supposed by those who know the weakening power of a single cup, but much dreaming and restlessness of a non-aphrodisiae type. The pulse is weak and quick, there is often an anaemic mur- COFFEE AND TEA INEBRIETY. 371 mur. The muscles waste quickly. The coffee inebriate is always thin. He may be a mere skeleton ; his eyes are bright and quick in movement, their pupils large ; and may be mistaken for a tea-drinker. In the insomnia wliich follows, when the coffee is removed, the only remedy is the old poison. As with tea-drinking, coffee addiction is followed by the employment of spirits and other drugs. Many inebriates and opium-takers have a history of excessive use of coffee before the other drugs were taken. The recognition of addiction to coffee is important in many cases of neurotics, especially in children and young persons, and unless promptly checked will be followed by serious results. The excessive use of coffee in all cases is a very significant hint of nerve-exhaustion and disorder of the motor nerves. In the late war many cases of delirium from coffee were noted where the food-supply was scant and coffee was abundant. Some of these cases came under special treat- ment, and yielded readily to baths, mineral waters, and strong foods. When coffee seems first to have been used for insomnia, the treatment must depend on a careful study of tlie etiology, and from the removal of the causes the cure may be expected. I have also noted a number of cases in young children of inebriate and neurotic parents who developed a morbid impulse for coffee. Such cases require active treatment, and milk, mineral waters, and baths are prominent remedies. Neurotic disturbances and diseases from coffee are but little known. Dr. Mendel, of Berlin, has lately published a clinical study of this neurosis, which is growing rapidly in this country. His observations were confined to the women of the w(;rking population in and about Essen. He found large numbers of women consumed over a pound a week, and some men drank considerable more, besides beer and wine. The leading symptoms were profound depression of spirits, and frequent headaches, with insomnia. A strong 372 DISEASES OF INEBRIETY. dose of coffee would relieve this, for a time, then it would return. The muscles would become weak and trembling, and the hands would tremble when at rest. An increasing aversion to labor and any steady work was noticeable. The heart's action was rapid, irregular, and palpitations and a heavy feeling in the precordical region were present. Dys- pepsia of an extreme nervous type was also present. Acute rosacea was common in these cases. These symptoms con- stantly grow worse, and are only relieved by the large quan- tities of coffee, generally of the infusion. In some cases the tincture was used. The victims suffer so seriously that they dare not abandon it for fear of death. Where brandy is taken only temporary relief follows. The face becomes sallow, and the hands and feet cold, and an expression of dread and agony settles over the counten- ance, only relieved by using strong doses of coffee. In all these cases, acute inflammations are likely to appear any time. An injury of any part of the body is the starting point for inflammations of an erysipelatous character. Melancholy and hysteria are present in all cases. In this country the coffee-drinker after a time turns to alcohol and becomes a constant drinker. In otlier cases opium is taken as a substitute. Coffee inebriates are more common among the neurasthenics, and are more concealed, because the effects of excessive doses of coffee are obscure and largely unknown. Man}'^ opium and alcoholic cases have an early history of excessive use of coffee, and are always more degenerate and difficult to treat. A very wide field for future study opens up in this direction. Dr. Slayter describes a case of delirium in a girl who chewed large quantities of tea. It appeared that masses of tea leaves had lodged in the bowels, and the delirium was in some measure dependent on the irritation and reflex actiofi which followed. Trembling delirium, and delusions of injury from others, gave it a strong resemblance to delirium tremens. The amount of tea chewed daily was TEA AND COFFEE INEBRIETY. 378 over one pound. The patient recovered by the use of free cathartics and the witlidrawal of the tea. In 1881 I saw a boy wlio had delirium and trembling that had existed at intervals for two months. The fact that his father had died an inebriate seemed to be a sufficient reason for his symp- toms in the minds of his friends. It was ascertained that he had for years drank large quantities of tea. Having been employed in a tea-store, he had chewed it freely. He was literally a tea inebriate. He had inherited an inebriate diathesis, and the early and excessive use of tea was a symptom of it. He had all the symptoms of one who was using alcohol to excess. He recovered, and a year later used coffee to great excess, until he became unfit for work ; then was under medical care for a time, recovered, and finally became an opium-taker. Another case came under my observation in the person of a little girl, twelve years old, the daughter of a patient under my care for inebriety. She had gradually and stead- ily become excessively nervous. Could not sleep, had mus- cular twitchings and delusions of fear ; would burst into tears, and complain that she was going to be turned out into the streets. She heard voices at night, and could not keep still. She also imagined that her fatlier was being burned. It was finally found that she was a tea inebriate, and botli drank and chewed it at all times and without any restraint. A physician consulted me about a singular stage of trembling and mild delusions which had appeared in a family of three old maids living alone in the country. It was found to come from excessive use of tea, and to be tea inebriety. When this was stopped they recovered. My observation leads me to think that these cases are not un- common among the neurotics. They are of such a mild character at first as to escape special observiition, and hence are supposed to be due to other causes. Such cases, after beginning on tea, take other drugs, and become aico- 374: DISEASES OF INEBRIETY. hol, opium, or chloral takers, or develop some form of neu- rosis, which covers the real and first causes. Theine is the active principle of the leaves of Cliinese tea, and is generally reputed to be identical with caffeine, both in chemical composition and in physiological action. My experiments show that it differs very markedly in physi- ological action from that of caffeine. Caffeine principally affects the motor nerves, while theine chiefly influences the sensory nftrves, and clinically proves itself a most valuable analgesic, surpassing morphia in promptness and permanency in relieving pain in some affections, without producing any, or at least very little, disturbance of the general nervous system. It paralyzes sensation before motion ; it impairs sensibility from the centre to the periphery and not, like brucineand cocaine, from the periphery to the centre ; it produces convulsions which are spinal and not cerebral ; it has a more powerful action on the sensory nerves, and less on the motor nerves than caffeine. From the results of theine in these cases it will be seen that it is a powerful anodyne without producing any intoxication of the higher nerve centres, which is so common with morphia and all other agents belonging to this class. Its influence is both quick and persistent, and it manifests an almost exclusive affinity for the sensory nerves. It relieves pain by acting from the centre toward the periphery and showing its effects but very seldom above the seat of injection. In i-io, 1-5, and even lA, grain doses it is entirely free from dangerous consequences — the only inconvenience which it causes is a slight, but transient burning at the point of introduction. I use a one percent, watery solution of Merck's preparation — ten minims of which equal one- fifth of a grain of theine. Larger doses are required in some individuals in order to bring out its characteristic action. TEA AND COFFEE INEBEIETT. 375 EFFECTS OF TEA DRINKING ON THE NUTRITION OF THE EYEBALLS. Dr. Wolfe has described the first effect as one of soften- ing of the vitreous humor, which became filled with floating particles of pigment. It had come under his notice in per- sons who at first sight seemed to have very little in common. He had found it among — i. The mining population, who pass a deal of time underground. 2. Washerwomen. 3, Middle-aged laborers, masons, and out-door workers. 4. Siiop and factory girls. 5. Not a few belonging to the upper classes. His attention was specially directed to the affection by its frequent occurrence among Australians who came to consult him. He could discover no assignable cause for the disease, either in the tissues themselves or in the history of the patient ; and it was only on directing his inquiries to their diet, and finding that ikey all agreed in consuming large quantities of tea, that he came to suspect its agency. A comparison of the numerous cases of opacity of the vitreous humor occurring among tea-drinking popula- tions, with its less frequency in France, Germany, and America, and its rarity among the Turks, tended to confirm his suspicions. Physiology did not suggest an explanation, but chemistry pointed to theine and tannic acid as most likely to cause disease. Theine might be left out of con- sideration, being identical with caffeine, which was innocu- ous ; so there only remained tannic acid. This precipitated albuminoids from their solutions ; hence it probably acted injuriously by precipitating some of the most important constituents of the food, and also by affecting the mucous membrane of the stomach and alimentary canal, and thus preventing digestion and assimilation. Some observations had been made as to the effects of tea-drinking on the healing of wounds and ulcers, by a Glasgow surgeon, wlio had noticed that, in persons addicted 376 DISEASES OF INEBRIETY. to this habit, they took on a sort of scorbutic character. Pliysicians also ascribed numerous cases of rebellious dys- pepsia to the use of tea. The disease of the vitreous humor above alluded to, could hardly be an isolated pathological fact, but must be associated with deleterious changes in other parts of the economy, and probably only made its appearance in organs which had a predisposition to be so affected. Without venturing upon any theory as to the action of tea on the vitreous humor, he would point out that the first expression of acute irritation of the fifth nerve in sympathetic ophthalmia was opacity of the vitreous humor and detachment of pigment from the whole uvular tract. So it was possible that chronic irritation of the same nerve might give rise to such changes in the nutrition of the eyeball as to brings about the condition under con- sideration. He commended this subject to the notice of general practitioners, who had better opportunities of judg- ing of it than he had. CHAPTER XXXVII. ON PSYCHOSIS CAUSED BY NICOTINE.- Nicotine is the most important chemical substance con- tained in tlie West Indian plant, nicotiana tabaciim ; when pure, it is a colorless, easily soluble fluid, of strong tobacco odor and very acrid, burning taste, is easily dissolved in water, alcohol, and ether, its reaction being strongly alka- line, and it forms simple crystallizing salts. It is said that Virginia tobacco contains the largest quantity of nicotine. Nicotine acts on the human organism as one of the most powerful poisons ; the action of tobacco differs only in degree. From experiments instituted in Professor Schroff's laboratory it results that the effects of nicotine on the healthy organism are as follows : Taken in doses of i to 3 milligrams, the alkaloid produced first an acrid burning sensation on tlie tongue and in the throat, with increased salivation, and a sensation of heat in the stomach, in the extremities, and in the whole body. Soon after this the phenomena are headache, vertigo, drowsiness, impaired vision and audition, accelerated and oppressed respira- tion. They were succeeded within half or three-quarters of an hour after ingestion of the poison by an extraordinary feeling of relaxation and weakness, the face became pallid artd the whole body as cold as ice ; fainting fits and vomit- ing made their appearance. The symptoms increased to tumultuous and chronic spasms of the respiratory muscles. After three hours the symptoms commenced decreasing, but secondary effects continued for several days. 377 378 DISEASES OP INEBKIETY. Subsequent experiments demonstrated tliat tlie first action of the poison is excitation, the ulterior action is depression and paralyzation. In the beginning the func- tions of the brain and of tlie spinal cord are enhanced, but this excitation is followed by relaxation and debility. The whole voluntary muscular system is subjected to tiiis influ- ence, which gradually extends to the heart, and finally to the vasomotor system. Such are tlie effects of this redoubt- able poison on the healthy organism, when taken in small doses of I to 3 milligrams. Wiiat may be the effects of the 1,200,000 kilograms of the same alkaloid, constituting the present amount produced on the whole surface of the globe.? It is impossible to ascertain in an exact manner the num- ber of men using tobacco, but it is asserted tliat approxi- mately they number 800,000,000. Each of them consumes on an average 1% grams nicotine ever}' year, or 4 milligrams every day, some of them less, others considerably more. The fact that large doses of this amount are supported by man proves once more the adaptability of the human nerv- ous system to injurious habits. The first contact with the tobacco poison is always felt by the cerebral nervous system as painful and hostile, and its repetition requires a certain violence against nature. By not heeding this warning of the attacked nervous cell, and by repeating the essays with tlie necessary perseverance, the repulsive sensation gradually vanishes and the excita- tion remains as a stimulus, which soon becomes indispen- sable. At last the irritation and debilitation of the cerebral nervous system reaches a degree in which privation is deemed a real suffering, and the same longing for renewed enjoy- ment of the poison manifests itself as is noted in alcoholists and morphinists. The action of nicotine differs considerably, not only ac- cording to the different classes of tobacco, but also accord- ing to its different applications. Smoking only allows the products of decomposition connected with it to exercise an ON PSYCHOSIS CA.USED BY NICOTINE. 379 influence, although several cases are known, not only of nerv- ous erethism, but even of perfect psycliosis, caused by excessive tobacco smoking. Kjellberg had several oppor- tunities of convincing himself that even a too abundant use of tobacco for snuflfing may originate psychic phenomena. But the greatest danger lies in the use of tobacco for chewing. The ordinary sliape for this application is to- bacco in rolls. It is true that small doses of it may be taken without causing psychic injuries. But as soon as the daily use exceeds lo to 12 grams of genuine and good tobacco, the field of pathologic phenomena is approached, and the sensation becomes an abnormal one. This transition is effected more rapidly in case pulverized snuff is used for chewing. In the last decades the use of snuff for cliewing has considerably increased in various northern countries, especially among mariners, manufacturing laborers, etc. From a number of cases observed by him, and in which a continued daily use of from 20-27 grams of tobacco in rolls, or in snuff, had been ascertained, Kjellberg has reached the conclusion that the similarity of symptoms points to a specific psychosis caused by the use of tobacco, ^^ nicotinosis mentalis," a real primary mental disease with its own peculiar symptoms, wliich are clinically distinguish- able, and which give it a place among mental intoxications. "■ Nicotinosis mentalis" is described by Kjellberg as follows : Among general symptoms a painful sensation of weak- ness and impotence is to be noted, accompanied very soon by hallucinations, maniacal ideas and suicidal inclination. Tlie disease has a prodromic stage and three distinct stages differing from each other. Prodromic stage — The patient has felt unwell for some lime, his general disposition changes, he shows an unusual uneasiness whicli may pass to a transient state of anguish. He sleeps little, and the ordinary occupations are repugnant to him. He is disposed to indulge in somber reflections, is tormented by palpitations of the heart and unusual anxiety. 380 DISEASES OF INEBRIETY. This condition continues for one and one-half and three months, when psychosis sets in. First stage. — The patient's attention is seized by lively hallucinations, and he is entirely occupied witli these new and surprising perceptions. He hears voices, visions appear to him, he lias a sensation as though something dif- ferent from himself was inside his body, and strange notions take hold of his conscience, from which he can't free him- self. False, fixed ideas often combine suicidal tendencies ; his mood is always gloomy ; the patient feels tired and exhausted, inclined to loneliness and rest ; at times he has short fits of fright. Otherwise he is quiet and obedient, talks little, and never without being previously requested to do so, but then what he says is logical and shows good per- ception. He complains of painful sensation in the heart, of wearisome insomnia and of voices that give him no peace. Nutrition is not impoverished, for the patient usually eats plenty, although he often speaks of bad appetite and spoiled food. After six or seven months the disease enters anew stage. Second stage. — The mental disposition improves, and we find the patient talks hilariously of his perceptions. He relates the visit of angels, he has seen heaven, but also hell and the evil spirits. He sings and talks to himself without interruption in a low voice ; motions become more vigorous, and he moves about with a certain agitation. The halluci- nations of brain and vision are on the increase, and the patient is constrained to execute involuntary motions. This condition is periodic, the periods usually lasting from two to four weeks with intervals of indefinite length. In such times the patient lays down prostrated and lazy, his mood is gloomy and discontented, his attention diminished, his per- ception very slow, his language distinct and logical, but hesitating. This stage may continue for a long time, but unless convalescence sets in, it passes gradually into a last stage. ON PSYCHOSIS CAUSED BT NICOTINE. 381 Third stage. — The intervals pass each other and periods of raised disposition disappear by degrees ; the mental dis- position remains quiet, perception is very limited. Hallu- cinations continue, and the patient gradually sinks into a state of general psvcliic debilit}^ while his physical condi- tion improves, and lie may even be partially serviceable for ordinary occupations. With regard to prognosis, it is not entirely bad during the first and second stages. But in the third stage recovery is not to be expected any more. Therapeutic treatment requires, first of all, absolute deprivation of tobacco, with the under- standing that it should be enforced by degrees, the patient being otherwise subjected to very painful sensations and much suffering. With this, substantial diet, motion in the open air, and use of mineral waters are to be recom- mended. CHAPTER XXXViri. EAU DE COLOGNE DRINKING AND ARSENIC TAKING. The use of cologne as a substitute for spirits is very common among inebriates ; generally when no other form of spirits can be procured. Recently attention has been turned to the rapidly increased consumption of cologne, both in large cities of Europe and this countr}^ and the conclusion reached by several authorities is that cologne is becoming a drink in many circles in preference to other forms of spirits. To many persons this odoriferous com- pound is very attractive, and especially when the cologne is made with methylated spirits its spirit strength is equal and exceeds many of the stronger alcoholic drinks in market. The factories for its manufacture in Cologne use the following general recipe : Twelve drops of the essential oils neroli, citron, bergamot, orange and rosemary ; one drachm of malabar cardamons to one gallon of rectified spirits. In this country cheap wood spirits are used, which gives greater alcohol strength at half the expense. In England many women and men in the better walks of life begin by taking a few drops of this perfume on sugar in the morning for some debility. This increases until they come to depend upon it the same as any other spirit com- pound. It can always be purchased with ease and without exciting suspicion, and can be used with great secrecy. American cologne is most often made from wood spirits, and is a very fiery, nauseous mixture, which cannot be taken in water, but used on loaf sugar or lozenges is endurable. 383 384 DISRASKS OF INEBRIETY. In one instance a wine glass of cologne was taken tliree or four times a day for a long time ; tiie patient finally died from delirium tremens. It appears tiiat the effects of tiiis drink vary but little from ordinary strong spirits, except, perhaps, tliere maybe more profound nutrient disturbances, insomnia, and tendency to delirium. If the cologne is made from wood spirits, the brain and nerve degeneration is both intense and profound, and delirium is very sure to follow. It has been asserted that melancholia and insomnia in a case suspected of using spirits in secret is an indication of the use of cologne. Usually the cologne-drinker will have a strong odor of this perfume about his body and breath which cannot be mistaken. Such cases usually use this per- fume externally in excess to divert suspicion from its internal use. Undoubtedly there are, in this country, an increasing number of cases where cologne is used secretly and exclusively. These cases, no doubt, become morphia, chloral, and cocaine inebriates after a time, and in some instances from a physician's prescription which contains these drugs, that are often fascinating substitutes. The alcohol and opium inebriates turn readily to cologne, and use it freely and with great satisfaction. The American inebriate, if a man, is not likely to use this perfume very long as a drink, but if a woman, it may be taken for years in secret. Obscure and complex nervous disorders in a woman that uses cologne externally should always suggest the possibility of its internal use. Inebriates who use it externally and recover rapidly, or make sudden changes of habits and living may be sus- pected of substituting it for other spirits. Cologne, both German and American brands, contains a large and vari- able per cent, of alcohol, and are always dangerous for use among neurotics, even externally. Its internal use is very likely to follow if the person has a great liking for this per- fume. In hospitals for the treatment of alcohol and opium cases cologne is found to be as dangerous as alcohol and is ARSENIC INEBRIATES. 385 Hot allowed. In private practice among neurotics the pos- sibility of this danger should always be considered. It is asserted tiiat the sale of cologne has increased enormously in certain sections of this country. Statistics on this point would be very interesting. We trust the coming census will throw some light on this, and the extent of the use of bitters in this country. ARSENIC INEBRIATES. In the highlands of Styria the prevalence of inebriety is limited, if not directly counteracted, by the strange habit of arsenic eating. Beginning with a minimum quantity, the devotees of the baneful drug gradually accustom their organism to a dose that would prove promptly fatal to any non-habitue, and persist in excusing their practice by all sorts of sophisms. Arsenic counteracts the raw air of the bleak uplands, it enables travelers to resist the fatigues of mountain-climbing, it stimulates digestion, etc., etc. " South of this city " (Gratz), writes an Austrian physi- cian, " arsenic eaters are found in nearly every village; there are families where the drug is used by every male adult, and often by white-haired patriarchs of seventy or eighty years, for it must be conceded that the habit is not incompatible with longevity. As a rule, I have been able to recognize a poison-eater by a certain moody appearance, contrasting strangely with the jovial disposition of the high- landers in general. A sallow, though clear and wax-like, complexion, is another characteristic symptom, and, in large doses, the use of the drug often involves serious digestive dii^rders. "It must be admitted, however, that arsenic never pro- duces anytliing like intoxication in the uglier sense of the word. The poison-eat^' directly after a large dose, feels elated ; his habitual moodiness gives way to a more buoyant disposition, but he does not become quarrelsome 386 DISEASES OF INEBRIETY. or maudlin-sentimental ; he can keep his temper in a lively controversy and the clearness of his intellect is not visibly affected. Nor are his financial circumstances apt to be imperiled by the habit. At retail rates, half a florin (twenty-five cents) worth of wliite arsenic will keep a whole family in stimulants for a couple of months. Very few inveterate poison-eaters can use up a florin's worth in tlie course of a year, while brandy drinkers often waste the wages of a week's hard work in the mad revels of a single night. And while one such night incapacitates or indis- poses the toper for work during the next forty-eight hours, an arsenic eater, under tlie full influence of his tonic, and for hours after, can follow his usual occupation as if noth- ing had happened." INEBBIETY FROM GINGER DRINKING. The increasing demand for ginger extracts and drinks is a very significant hint of a new phase of the morbid drink impulses of the age. Several large proprietary establish- ments are devoted exclusively to the preparation of ginger extracts, essences, and drinks, which are extensively adver- tised as medicines and preventive drinks for the diseases of the different seasons. It is a well-known fact that all these preparations are made with the poorest, cheapest spirits, and contain from thirty up to eighty per cent, of alcohol. In some instance wood spirits are used on account of the clieapness, and the intoxicating qualities of this mixture are far worse than any alcoholic drinks of commerce. The demand for these ginger drinks is due to the alcohol they contain, the ginger in itself having but little influence on tlie body, altliough some entliusiastic writers assert that ginger taken in large quantities produces a distinct form of inebriety, marked b}' stupor and melancholy. In two cases which have been reported where extract of ginger was taken in large quantities, profound nutrient GINGER INEBEIETT. 387 disturbances, and inanition were present. The intoxication was less maniacal, and attended with profound depression. This would undoubtedly depend on the alcohol more than the ginger. From inquiries it appears that there are a large number of persons who buy extract of ginger regularly, apparently using it as a common drink. The probability is that after a few months or years they abandon this drink for some stronger alcoholic drinks, or narcotics. A New York druggist writes : "That the sale of ginger extracts to women are rapidly increasing ; that he has over a dozen regular customers, who buy from two quarts to one gallon of ginger a week." The sale of ginger in Maine was so great, that it was declared by the courts to be an intoxicant, and placed among the alcoholic drinks prohibited. From a variety of evidence there can be no doubt that ginger drinking in this country has reached a dangerous magnitude, and those who use it any length of time are almost certain to become alcoholic or opium inebriates. The extracts of ginger on the market are without excep- tion dangerous, because of the dangerous alcohols they con- tain. Neuraesthenics and neurotics should avoid them as poison, and inebriates of every form will always find them treacherous remedies for every condition. For all the vari- ous functional disturbances they are supposed to relieve, pure alcohol is far safer, and less injurious. The following item is of interest : An officer of a church accused the pastor of being a ginger inebriate. A trial followed and Dr. Day was called as an expert. The peculiar conduct of the clergyman, with the great number of extra ginger bottles found in his pri- vate study, with other evidence, pointed to the conclusion that he was a secret ginger inebriate. Dr. Day said that for a long time he was convinced that the use of alcohol, plain and simple, was being superceded by a preference for new- fangled nerve tonics that possessed substantially the essen- 388 DISEASES OF INEBRIETY. tial properties of alcohol, without the disagreeable repu- tation, and to discover what peculiar forms this new manifestation was taking. For thirty-one years he had been treating nearly one hundred cases yearly that displayed all the symptoms of alcoholic delirium when the cause of disease was not, strictly speaking, alcoholic indulgence. Besides chloral and cocaine inebriates, of which we always have more or less, I had a man who used to get furiously drunk on quinine. He'd stagger about and yell like a regular whiskey drunk, and he'd go tiirough all the successive stages of a common intoxication. He'd get jovial and pleasant first, and then cross and savage, and finally maudlin. He was a very interesting case. I have seen some cases suffering from the effects of the use of patent medicines ; for instance. Many of these nerve-tonics and so-called patent foods are cultivators of an intemperate habit that results in mental and physical manifestations very similar to the indications of excessive alcoholic indul- gence. A well-known proprietary food was nothing better than an alcoholic stimulant. In regard to Jamaica ginger: " It takes tlie strongest kind of alcoliol to preserve Jamaica ginger, and the tinc- ture of this substance is extremely inebriating when used even in small quantities. I knew a patient who used to get drunk on a spoonful or two of this stuff, and there isn't any doubt that a great many people use it as an intoxicant. Anything almost acting as a stimulant to the nerves may he" used as an intoxicating agent. I knew a man who gol quite drunk on a strong cigar, and I've had several case? of physical derangement of pronounced alcoholic appear, ance from excessive smoking. Tobacco and alcohol seem to have a very close identity. Many a drunkard will rest comparatively content when deprived of his liquor, if a good supply of tobacco is fuinished him, and many an inveterate tobacco user falls into drink when he is deprived GINGEK INEBKIETY. 389 of the favorite weed. I knew a confirmed tea-drinker who was badly sliattered from tlie excessive indulgence in what the poet calls " the cup that cheers, but not inebriates," and there are instances of mild intoxication resulting from too much tea-drinking. " The tendency of these days seems to be toward new forms of inebriety, and the effect of alcoholic indulgence now is much more injurious, because the practice of adul- teration has become so extensive. Then the odium which attaches to the use of alcohol has led many people in high places to cultivate a habit of secret tippling, and such people frequently devise an original method of securing the effect of inebriety without subjecting themselves to the charge of using alcohol. Consequently the use of out- landish and sometimes deadly drugs is clearly on the in- crease." APPENDIX. DRUNKENNESS AS A DEFENSE. BY CLARK BELL, ESQ. The law as now settled in England and the American States ma}"^ be stated as follows : While drunkenness is not per se a defense upon a charge of crime, yet mental unsoundness, superinduced by exces- sive intoxication and continuing after it has subsided, may excuse ; or where the mind is destroyed by a long-continued habit of drunkenness ; or where the long-continued drunk- enness has caused an habitual madness, which existed when the offense was committed, the victim would not be respon- sible. For if the reason be perverted or destroyed by a fixed disease, although brought on by his own vices, the law holds him not accountable : Rex v. Meakin, 7 Car. & P., 297 ; Reume's Case, i Lewin, 76 ; Reniger v. Fogassa, Plow., I ; I Russ. on Crimes (9th ed.), 12 ; i Bishop Cr. L. (6tii ed.), 406 ; i Wharton Cr. L. (8th ed.) sec. 48 ; McDon- ald C. L. of Scott., 16 ; I Hale, 4 ; Black. Com., 26 ; Beasley V. State, 50 Ala., 149 ; Peo. v. Odill, i Dak. Ter., 197 ; Estes V. State, 55 Ga., 30 ; Baily v. State, 26 Ind., 422 ; Roberts V. People, 10 Mich., 401 ; s. c, 19 Mete, 402 ; State v. Hundley, 46 Mo., 414 ; State v. Thompson, 12 Nev., 140 ; 391 392 APPENDIX. Lanergan v. People, 50 Barb. (N. Y.), 266 ; Maconnehey 7>. State, 5 Ohio, 77 ; Com. v. Green, Ashm. (Pa.), 289 : U. S. V. Forbes, Crabbe (D. C), 558 ; Stuart v. State, 57 Tenn., 178 ; Carter v. State, 12 Texas, 500 ; Bell's Med. Jurisp. of Inebriet}^ p. 10, and cases there cited). The rule of law is well settled that evidence of intoxica- tion is always admissible to explain the conduct and intent of the accused in cases of homicide, although the rule does not apply in lesser crimes, where tlie intent is not a neces- sary element to constitute a degree or phase of the crime. Bell's Med. Jur. of Inebriety, p. 10, and cases there cited. In cases where the law recognizes different degrees of a given crime, and provides that willful and deliberate inten- tion, malice, and premeditation must be actually proved to convict in the first degree, it is a proper subject of inquiry wiiether the accused was in a condition of mind to be capable of premeditation : Gray. J., in Hopt v. People, 104 U. S., 631 ; Buswell on Insanity, § 450 ; Penn v. McFall, Addison, 255 ; Keenan v. Commonwealth, 44 Pa. St., 55 ; Jones V. Com., 75 Pa. St., 403 ; State v. Johnson, 40 Conn., 136 ; Pirttle zk The State, 9 Humph., 663 ; Haile v. State, 11 Humphrey, 154 ; Smith v. Duval (Ky.), 224 ; Bosswell v. Com., 20 Gratt., 860 ; Willis v. Com., 32 Gratt., 929 ; People ZK Belencia, 21 Cal, 544; People v. King, 27 Cal., 507; People V. Lewis, ;^6 Cal., 531 ; People v. Williams, 43 Cal., 344 ; Farrell e;. State, 43 Texas, 508 ; Colbath v. State, 2 Tex. App. 391 ; State v. White, 14 Kan., 538 ; Schlacken v. State, 9 Neb., 241 ; 104 U. S. The reason of this rule of law rests upon the fact that intoxication is a circumstance to be weighed in connection with the other circumstances surrounding the commission of the act in determining whether it was inspired by deliber- ate and malicious intent, and whether immediately before and at the time of his act the intoxication of the accused was so great as to render him incapable of forming a design or intent, which the jury must find from the facts in the APPENDIX. 393 case, without regard to the opinions of others: Buswell on Insanity, § 452 ; Marshall's Case, i Lew. Cr. Cas., 76 • Thacher, J., in Kelly v. State, 3 S. & M., 518 ; Armor v. State, 63 Ala., 173 ; People v. Belencia, 21 Cal., 54. And because, since he who voluntarily becomes intoxi- cated is subject to the same rules of law as the sober man, it follows : that where a provocation has been received whicii, if acted upon instantly, would mitigate the offense if committed by a sober man, the question in the case of a drunken man sometime is, whether such provocation was in fact acted upon, and evidence of intoxication may be con- sidered in deciding that question : Buswell on Insanity, § 423 ; State v. McCants, i Speer, 384. The New York Penal Code defines precisely this ques- tion of responsibility in that State in such cases as follows : "§ 22. Intoxicated persons. — No act committed by a per- son while in a state of intoxication shall be deemed less criminal by reason of his having been in such condition. But whenever the actual existence of any particular pur- pose, motive, or intent, is a necessary element to constitute a particular species or degree of crime, the jury may take into consideration the fact that tiie accused was intoxicated at the time, in determining the purpose, motive, or intent, with which he committed the act." DELIRIUM TREMENS AND THE LAW. The rule of law is well established both in Engand and the United States, that insanity produced by delirium tre- mens is a good defense to a ci'iminal charge. Even if induced by intoxication, the victim is no more punishable for ills acts than if the delirium had resulted from causes not under his control : Regina v. Davis, 14 Cox C. C, 563 ; Bell on Med. Juris, of Inebriety, 9, and cases there cited ; J. Crisp Poole, Med. Leg. Jour., vol. 8, p. 44 ; U. S. V. 394: APPENDIX. McGIue, I Curt., i ; Wharton's Crim. Law (8th ed.), sec. 48 ^ People V. Williams, 43 Cal., 344 ; U. S. v. Clarke, 2 Cr. C. C, 758 ; Lanergan v. People, 50 Barb. (N. Y.), 266 ; s. c, 6 Parker, Cr. R. (N.Y.), 209 ; O'Biien v. People, 48 Barb., 274 ; State V. Dillahunt, 3 Harr. (Del ), 551 ; State v. McGonigal, 5 Harr. (Del.), 510 ; Cluck v. State, 40 Ind., 563 ; Bradley V. State, 26 Ind., 423 ; O'Herrin v. State, 14 Ind., 420 ; Dawson v. State, 16 Ind., 428 ; Fisher v. State, 64 Ind., 435 ; Smith V. Com., i Day (Ky.), 224 ; Roberts v. People, 10 Mich., 401 ; State v. Hundley, 46 Mo., 414 ; State v. Sewell, 3 Jones (N. C), L., 245 ; Corn well v. State, Mart & Y. (Tenn.), 147 ; Carter v. State, 12 Tex., 500 ; Boswell v. Com., 30 Gratt. (Va.), 860 ; U. S= v. Drew, 5 Mason C. C.» 283. INDEX. Page Accidental Inebriates 27 Adversity in Inebriety 80 Alcoholic Delirium and its associated conditions. .. . 131 Alcoholic Heredity 145 Alcohol as a Paralizant. . . 181 American Association for the Study and Cure of Inebriety 5, 25 Anstie, Dr 167 Arsenic Inebriety 383 Asylums, History of 22, 215 Asylums in America 24 Alchol and Beer on the brain 113 Beard, Dr. G. M 73-93 Beer Drinking in this Country 116 Bellows, Dr 202 Bell, Clark 277,285 Blandford, Dr 164 Binghampton Asylum, 24, 76, 216 Carpenture, Dr 247 Cholera in Inebriety 102 Page Chronic Dipsomania, 35 Chloroform Inebriety 363 Clouston, Dr 113 Climatic period in Ine- briety 119 Classification of Inebriety. . 27 Climate in Inebriety. .65, 93, 124 Coma in Inebriety 306 Cocaine Inebriety 357 Consumption in Inebriety. . 103 Conditions favoring Ine- briety 39 Connor, Dr 363 Cofifee Inebriety 369 Cologne Inebriety 383 Connecticut State Medical Society 21 Crothers, T. D., 17, 55, 66, 116, 145, 316, 297 Criminal Inebriates 289 Cure of Inebriety 198 Day, Dr. Albert, 213,223, 374, 387 Dacaiene, Dr 170 398 INDEX. Page Delirium Tremens, Febrile. 137 Delirium Tremens Trauma- tics 142 Details of Treatment 203 DeZouche, Dr. 239 Disease theory, History of 17 Disease theory in Modern Times 22 Dipsomania, its History and Relation 29 Disability of Alcoholized Cases "]"] Diathesis Inebriate 52 Dietetic diseases in Ine- briety 57 Diagnosis of Inebriety 118 Differentiation of Inebriety. 309 Drinking from Association 175 Duty of State in Treatment of Inebriates 239 Dyspepsia 57 Early history of Dipsomania 3 1 Education in Inebriety 59 Emotional Inebriates 28 Elliott, Dr 209 Epilepsy, its relation to Inebriety 48 Ether Inebriety 347 Exhaustion in Inebriety... 70, 80 Fort Hamilton Inebriate Home 123, 256 Head Injuries in Inebriety. . 31 Heredity, Opium 319 Heredity, Alcoholic 145 Heredity, Psychical 147 Page Heredity, History of 155 Heredity, its Extent and.. Statistics 156 Hughes, Dr. C. H 317 Hospitals in Europe 25 Inebriety and Coma 309 Inebriety from Opium 317 Inebriety from Ether 347 Inebriety from Cocaine.... 357 Inebriety from Chloroform 363 Inebriety from Coffee and Tea 369 Inebriety from Tobacco. . . . 377 Inebriety from Cologne. .. . 383 Inebriety from Arsenic 385 Inebriety from Ginger 386 Inebriate Asylums. .24, 203, 217 International Congress for the Study of Inebriety. 26, 92 Insanity of Inebriates 242 Inebriety, Predisposing Causes 55 Inebriety among Women.. 61 I nebriety from Heat 63 Inebriety and Sun-stroke. .86, 87 Inebriety among many American Women 92 Inebriety in Epidemics.... 102 Inebriety and Consump- tion 103 Insanity and Inebriety. .242, 271 Inebriate Asylums, History of 22, 217 Inebriates in Asylums 246 Inebriate, Legal Control of, 221, 253 Inebriates, Criminal 302 Inebriate's Responsibility.. 283 IHDEX. 899 Page Inebriety, Law and Rulings of 276 Irresponsibility of Inebriates 297 Jackson, Dr..... 83,227 Jewell, Dr. J. G 182 Journal of Inebriety. .... .vi., 25 Kemp, Dr. E.J 187 Kerr, Dr. Norman, 168, 174, 243,271, 277, 347 Law and rulings of Judges in Inebriety 277 Lett, Dr. Stephen 222 Lentz, Dr. F 260 Legal care of Inebriates. 221, 253 Lykke, Dr 29, 171 Maudsley Dr 59 Mays, Dr. Thos. J 103 Mason, Dr. L. D., 118, 123, 220, 251 Mann, Dr. E. C 206 Mattison, Dr. J. B. .232, 329, 340 Marriage and Heredity 152 Matthews, Dr 161 Mendel, Dr 360 Mental Heredities I47 Military Hospitals 200 Morris, Dr. John 309 Morel, Dr 163 Mortality of Inebriety 100 New York State Inebriate Asylum 23 Neursesthenia in Inebriety, 81, 1S2 Nicotine 377 Page Occupation of Inebriates. . . 123 Opium Inebriety 317 Opium Neuroses 313 Opium Diathesis 321 Opium Classes 319 Opium allied diseases 317 Opium Special Treatment. . 329 Opium Heredity 331 Opium Medical Treatment. 329 Parrish, Dr. J 119, 244 Pathology of Brain Feeble- ness 39 Pauper Inebriates 28, 251 Pathology of Inebriety. 173, 185 Periodic Dypsomania 29 Politics in Inebriety 76, 98 Philosophy of Inebriety 41 Predisposing Causes of Ine- briety 55 Premeditation in Inebriety, TJ, 122, 146 Prognosis of Inebriety. . 197, 209 Psychical Traumatism in Inebriety 73 Psychological Forces in Ine- briety 90 Punishment does not deter Inebriates 198 Quimby, Dr. I. N 241 Rest in Inebriety 182 Results of Treatment.. .128, 183 Responsibility of Inebriates. 2S3 Richardson. Dr. B. W 258 Roberts, Dr. John B 139 Rush, Dr 19 400 INDEX. Page Searcey, Dr. J. T 39 Shepard, Dr. C. H 234 Slayter, Dr 372 Solitary Inebriates 28 Special Hospitals for Inebri- ates 220 Statistics of Heredity. ..156, 161 State Hospitals for Inebri- ates 248, 260 Syphilitic Diathesis 54, 377 Temperature in Inebriety. . 84 Tea Drinking on the eyes. . 375 Tea Inebriety 376 Thwing, Dr. E. P 90 Theane Inebriety 372 Tobacco Inebriety 377 Treatment, General Princi- ples 197 Transmissibility of Inebriety 168 Tuke, Dr 165 Treatment by Hot-air 234 Treatment by the State 239 Trance in Inebriety 297 Treatment, Failure of, 85, 150, 240 Page Treatment, Duration of, 306, 248, 256 Treatment, Form of 215 Treatment by Restraint 255 Treatment by Medicines. 206, 21 1 Treatment, Results of. . 128, 197 Treatment, Hygienic 227 Traumatic Delirium Tre- mens 142 Treatment of Delirium Tre- mens 143 Treatment of cases of Heredity 150 Traumatism in Inebriety.. 66 Turner, Dr. J. Edw 22. 216 Types of Inebriates 29 Washingtonian Movement. 22 Washingtonian Home 22 Women Inebriates 61 Wolf, Dr 375 Winslow, Dr. Forbes 166 Woodard, Dr 21,215 Wright, Dr. T. L., 47, 162, 173, 179. 270 Wynter, Dr i66 THE INTERNATIONAL MEDICAL ANNUAL. A Complete Work of Reference for Medical Practitioners. By a Corps of Thirty-Seven Specialists and De- partment Editors, widely known in Europe and America. THE MEDICAL ANNUAL brings to the Practitioner, in a form for rapid reference, every advance in medical knowledge, worthy of record or preservation, It differs from a Retrospector Difjest; in tlielarfcie number, and scope of its original and special papers, ils Practical Hints and Suj^gestions. Each review and contribution being credited to its respecti^e author thus giving merit, character and increasing value to i he production. Its 6000 or more references to Diseases and their Treatment is comprised in : — FIRST.— A DICTIONARY OF NEW REMEDIES; such as have recently come to the notice of the roedi<;al professinii in Europe and America and the result of experiments with, and new uses of many ^alu- able dru^s that have lost the charm of novelty; with an index of the diseases to which a given remedy may apply, including a review of the general Thera- peutics of the year. SECOND.-A DICTIONARY OF NEW TREATMENT; a remarkably full resume of the medical progress of the year, giving the new methods of treatment in Medicine and Surgery contribuitd from all parts of the world, such as have been tested, recommended and found worthy of a place among the archieves of Medical literature. The whole arranged in encyclopsefiia form under the name of the disease; by specialists and editorb in charge of the several departments. THIRD. — APPENDIX, comprising Special Contributions such as Sanitary Science; Progress of Pharmacy; New Inventions and Ap- pliances ; Books of the Year, etc., etc. ITS YEARLY ISSUES since 1883 form a complete and permanent Library of Medical Rt-ference of great value to the dispensing chemist as well as the Medical Practitioner. In one large octavo volume, illustrated. Nearly 700 pages. $2,75* Back Volumes can be had only of 1889, 90 91,92,93, post-paid, $2.75 each. E. B. TREAT, Publisher, 5 Cooper Union, N. Y. Surgical Handicraft. -A MANUAL- OF Surgical Manipulations, Minor Surgery, and other matters connected with the work of House Surgeons and Surgical Dressing. By WALTER PYE, F.R.C.S., Surgeon to St. Mary's Hospital and the Victoria Hospital for Sick Children , late Examiner in Surgery at the University of Glasgow. UPWARDS OF 300 ILLUSTRATIONS ON WOOD, FIRST AMERICAN EDITION, From the Third London Edition, Revised and Edited toy T. H. R. CROWLE, F.R.C.S., Surgical Register to St. Mary's Hospital, and Surgical Tutor and Joint Lecturer on Practical Surgery in the Medical School. " The subjects cover the whole range of surgery. The book is an exceedingly i^ood guide for those for whom it seems to be intended, and it furnishes not only "-liem but the geneial medical practitioner with an excellent book of reference for any emergency which may ariae. The matter is well chosen, the style is clear and pleasant, the illustrations are many of them new, and the methods of treatment described are fully up to date. It is different in its scope from any book on minor •surgery with which we are acquainted, and it compares favorably with them all." — The New York Medical Journal. Edinburgh Medical Journal says: — "Such a rapid sale of the first edition is in itself a strong testimony to the favour with which the work has been received by the profession. The book can be recommended as a really useful one, containing much practical information, described in a clear and interesting way. Recent authorities have beea consulted, so as to bring the matter well up to date. The illustrations are excellent, and have all the vividness of gond life portraits. The presence of special chapters on subjects not usually treated of in works of this kind is a distinct advantage." The Therapeutic Gazette says: — "In the main it is thoroughly reliable, covers the principal points intended by its author, is clearly expressed, is excellently illustrated, and is a useful addition to the surgeon's library," British Medical Journal says: — " We had occasion to notice favourably the first edition of this manual. The work is a very practical and useful one, and the author is to be congratulated upon its success. The book is certainly worthy of its author's repufaii m, nnd can be safely recommended." New England Medical Monthly says: — "As a book of minor surgery it seems t > be complete in every respect, covering the whole range of varied subjects. Its sale when it was first issued abroad was phenomenally rapid and it received the general commendation of the profession The illustrations are grand, the paper is perfect and it is typographically splendidly gotten up." In One Octavo Volume, 600 pages, and upwards of Three Hundred Illustrations. Cloth, $3.50 net; Sheep, $4 net. E. B. TREAT, Publisher, 5 Cooper Union, N. Y. PHOTOGRAPHIC ILLUSTRATIONS OF 5KIN DISEA Upwards of One Hundred Cases from Life. By GEORGE HENRY FOX, A.M., M.D., Clinical Professor of Skin Diseases, College of Physicians and Surgeons, New York; Trof.of Diseases of the Skin, Post Graduate Medical School and Hospital, New York ; Physician to the New York Skin and Cancer Hospital; Fellow of the American Academy of Medicine : Member of the New York Dermatological Society, the Ameri- can Dermatological Association, etc. The extensive sale of this work, and the acknowledged appreciation and prestige by the Profession of the first Edition of Dr. Fox's " Photographic Illus- trations of Skin Diseases," proved conclusively the value of photography in accurately portraying the various phases of cutaneous disease, and the con- tinued demand for these plates is ample evidence of their merits and adapta- tion to the wants of the general practitioner. The second series is a complete remodelling of the subject, in which a new and better class of illustrative cases are presented and the total number in- creased fifty per cent., including several important affections, omitted in the f rmer work, are now beautifully illustrated, making the series as complete as possible. In place of the few pages of descriptive matter, which accompanied the original plates, a notable enlargement of the text, fully one hundred per cent, is a leading feature of the present edition. The diagnosis and the treatment of skin diseases are especially considered, and the text, consisting of upwards of two hundred quarto pages, is designed as a complete work on Dermatology. In its present form the work appears as a combined Atlas and Text Book. As heretofore, the plates are made from photographic negatives taken from life, the cases having been carefully selected from the large number which have come under the author's observation in private and hospital practice and the contributions of his collaborators in Dermatology. The Artotype repro- ductions of these negatives — by a process rendering them indelible, and, unlike photographs, will not fade by age or exposure — are made by Mr Ed- ward Bierstadt, the widely known art printer, and the hand-coloring of the plates, giving the lifelike effect of the disease, an important feature of the work. The work is complete in Twelve Parts, $2 Each, and com- prises upwards of loo cases, printed from the original photographic negatives, by the Artotype process, on fine steel-plate cardboard, 10x12 inches, colored by hand; with upwards of 200 quarto pages of text, including treatment. The complete work, fully Indexed, substantially bound in Half Morocco, hinged plates. Price, $26.75. Cutaneous Syphilis; a companion volume, Seventy Cases from Life, by the same author, same style and price. AGENTS WANTED. E. B. THE AT, rub,, S Cooper Union, K. Y, Tie Jml Bl lirie Published Quarterly by the American Asso- ciation for the Study and Cure of Inebriety. This Joiirna] was established in 1876 and is devoted ex- clusively to the scientific study of Inebriety, Nar'^omania and all toxic diseases. Its special object is to point out the physiological and psychological laws which underlie alcohol and inebriety in all its forms, and indicate the methods of cure and prevention. It seeks to solve practically the problems, " What shall we do with the Inebriate ?" " What is the position of Alcohol in medicine?" and to furnish such hints and facts that will enable the prac- titioner to both understand and apply remedies in the early stage, and thus save many from chronic, incurable conditions. It is the only journal published coniined entirely to the medical study of this the most difficult scientific and social problem of the century. This journal will bring to the reader the rapidly accu- mulating facts along this new field of study from all parts of the world and by all the leading students and writers. Subscription price, only $2.00 a Year. Address all cotnmunications, T. D. CROTHERS, M.D., HAKTFORD, CONK DATE DUE UES r at the wing, as ent with Demco, Inc. 38-293 C28(946) MlOO o„«P RC565 Ain53 American Association for the Study and Cure of Inebriety, The diseases of inebriety.