'W^^^I^^S, HX64151530 C872 •R42 C'Q^"^^' f^°^P^°'°9y ' RECAP "RC«12 "RM-Z. College of ^fjpsiciansi anJi burgeons! Htbrarp Digitized by the Internet Archive in 2010 with funding from Open Knowledge Commons http://www.archive.org/details/cloacalmorphologOOrick Cloacal Morphology in its Relation to Genito- Urinary and Rectal Diseases. (With 54 Plates and 93 Illustrations.) BY BENJAMIN MERRILL RICKETTS, Ph.B., M.D., LL.D., F.A.C.S. Member American Medical Association; (House Surgeon N. Y. Skin and Cancer Hospital, 1S84-5); Ohio State Medical Society; Western Surgical and Gyneco- logical Association; International Medical Congress, 1887; International As- sociation Railway Surgeons; Mississippi Valley Medical Association; Cin- cinnati Academy of Medicine; Honorary Member Medical Society State of New York; Honorary Member St. Louis Medical Society; Fellow New York State Medical Association; Member Societe Internationale de Chirurgie; American Urological Association; American Proctological Society; Cincinnati Society of Natural History; Pan-American Congress; Honorary Professor of Surgery of the Tliorax and its Viscera; Barnes and American Medical Colleges; National University of Arts and Sciences, St. Louis, Missouri, and Clinical Congress of Surgeons of North America; Author of Volumes What to Do in Case of Accident; Surgery of the Prostate, Pancreas, Diaphragm, Spleen, Thyroid and Hydrocephalus, Surgery of the Ureter, Surgery of the Heart and Lungs and Surgery of the Thorax and Its Viscera; Founder and Director of the B. Merrill Ricketts Experimental Surgical Research Laboratory, Cincinnati, Ohio, etc., etc., etc., etc., etc., etc., etc. CINCINNATI 1916 Published by the Author MCMXVI. (1916.) Copyright, 1916, by Benjamin Merrill Ricketts This work is dedicatea to HOWARD AYERS, B.S., Ph.D., L.L.D., Morpholo- gist and Advocate of Scientific Research. Everything has a beginning, an existence, and an ending, with changes of equal interest and importance. It is therefore necessary to become famihar with creation that existence and dissolution may be better understood. The thing created should be more perfect than its creator, its existence superior and its dissolution more natural, but there are errors and variations evidenced upon every hand, among them changes in the cloaca which are herein considered. (B. M. R.) INTRODUCTION. For fifteen years the anatomical relation of the perineum, coccyx, uro-genital and rectal tracts has been attractive to me, especially symptomatology, which so much con- cerns them and which is so much in doubt. But not until a more recent time, when the importance of the pudic nerve and its many changes in distribution resulting from changes in the cloaca to 4orm the perineum were suggested, was I convinced of the great similarity of physiologic symptoms due to their anomalies, diseases and injuries, and now at the con- clusion of this research, I find this thought crystallized into one more certain and enduring. Especial attention has been given to the pudic nerve, lymphatics. Glomus coccygea, coccyx, Cowper's and Bartholin glands, because they play a more important role in symptomatology than has ever been ascribed to them. With the exception of the Glomus and Coccyx, no form of treatment is considered throughout this work. I have quoted freely from many authors, not only in histology, but in the general text, because I felt my incompetency and because time would not permit of a more general research. If therefore, I have been permitted to reflect only a delicate ray of light upon this suggestion, the purpose of this work will have been served. I desire to thank Dr. D. D. DeNeen for his assistance in preparing the work on the lymphatics, Miss Gladys Ayers and Hawley Zwick for photographic illustrations. Miss Ayers for copy, my students Miss Nevada Hannah and Mr. R. A. White for assistance in the preparation of the copy, Drs. Sappy, Cuneo, and Marcille, Deaver, Piersol, Kelley, Schumacher, Jakobsson and others for permission to use illustrations and quote text. I also want to express my deep appreciation to Mr. Howard Ayers for his contribution, valuable suggestions and encouragement in this research, and to the A. R. Fleming Print- mg Company for producmg the book m a form so pleasing. Benjamin Merrill Ricketts, February 14th, 1915. N. W. Corner Fourth and Broadway, Cincinnati. Page Five CONTENTS Chapter I. Chapter II. Chapter III. Chapter IV. Chapter V. Chapter VI. Chapter VII. Chapter VIII. Chapter IX. Chapter X. Chapter XI. Chapter XII. Chapter XIII. Chapter XIV. Chapter XV. Chapter XVI. Chapter XVII. Introduction. A Summary of Development of the Rectum and Urogenital Sinus from the Cloaca. Illustrated. Perineum. — Anatomy, Anomalies Diseases, Injuries and Symptoms. Illustrated. Definitions. — Of Etiology, Symptoms and Diagnosis. Blood Vessels. — Anatomy, Anomalies, Diseases, Injuries and Symptoms. Illustrated. Nerves. — Anatomy, Anomalies, Diseases, Injuries and Symptoms. Illustrated. Ly^mphatics. — Anatomy, Anomalies, Diseases, Injuries amd Symptoms. Illustrated. Glomus Cocc^gea. — Anatomy, Anomalies, Diseases, In- juries and Symptoms. Illustrated. Bibliography. Coccyx. — Anatomy, Anomalies, Diseases, Injuries and Symptoms. Illustrated. Bibliography. Urethra. — Anatomy, Anomalies, Diseases, Injuries and Symptoms. Illustrated. Bladder. — Anatomy, Anomalies, Diseases, Injuries and Symptoms. Illustrated. Ureters. — Anatomy, Anomalies, Diseases, Injuries and Symptoms. Illustrated. Kidneys. — Anatomy, Anomalies, Diseases, Injuries and Symptoms. Illustrated. Erectile Body. — Anatomy, Anomalies, Diseases, Injuries and Symptoms. Illustrated. Prostate Gland. — Anatomy, Anomalies, Diseases, Injuries and Symptoms. Illustrated. CoTvper's Glands. — Anatomy, Anomalies, Diseases, In- juries and Symptoms. Testicles. — Anatomy, Anomalies, Disecises, Injuries and Symptoms. Illustrated. Spermatic Ducts. — .Anatomy, Anomalies, Diseases, Injuries and Symptoms. Illustrated. Page Sevin Chapter XVIII. Scrotum. — Anatomy, Anomalies, Diseases, Injuries and Symptoms. Illustrated. Chapter XIX. Vagina. — Anatomy, Anomalies, Diseases, Injuries and Symptoms. Illustrated. *^ Chapter XX. Bartholin Glands. — Anatomy, Anomalies, Diseases, In- juries and Symptoms. Illustrated. Chapter XXI. Clitoris. — Anatomy, Anomalies, Diseases, Injuries and Symptoms. Illustrated. Chapter XXII. Uterus. — Anatomy, Anomalies, Diseases, Injuries and Symptoms. Illustrated. Chapter XXIII. Ovaries. — Anatomy, Anomalies, Diseases, Injuries and Symptoms. Illustrated. Chapter XXIV. Fallopian Tubes. — Anatomy, Anomalies, Diseases, Injuries and Symptoms. Illustrated. Chapter XXV. Rectum. — Anatomy, Anomalies, Diseases, Injuries and Symptoms. Page Bight CHAPTER 1. A Summary of the Development of the Rectum and Urinogenital Sinus from the Cloaca. CLOACAL-COCCYGEAL HISTORY. By HOWARD AYERS. N VERTEBRATE anatomy the term cloaca is applied to the common chamber into which, in many forms, the intestine, the ureters and the genital passages discharge. Reptiles and birds all possess a cloaca generally well de- veloped. Since both birds and mammals are descended from the reptilian stock by divergent paths of development we would expect to find traces of such an important organ as the cloaca in the mammals also. Living in Australia today, we find two primitive mammalian forms, the duck-bill (Ornithorhynchus paradoxus) and the spiny ant-eater (Echidna hystrix). Both of them are egg-laying mam- mals — laying eggs like a reptile or bird and after hatching the eggs in their abdominal pouches, nourishing the young with a milk secretion from rudimentary or better — primitive milk glands. They are clearly transitional forms between the reptihan stock and the mammalian stock. These two forms are classed as Monotromes because they have only one external opening for voiding the contents of intestine, ureters and genital tubes. They are cloacal mammals and the cloaca is preserved in reptilian per- fection. While none of the higher mammals normally possess a cloaca in the adult state, all of them pass through a stage in embryonic growth in which the cloacal apparatus is fully developed. However, before the permanent condition is reached the cloaca is generally obliterated as a common chamber and it becomes separated into two tubes, one for the reception of the intestine, the other for the ureters and the genital canals. This separation always occurs, except when the developmental processes are in- terrupted or inhibited. Such inhibitions do occur and that not infrequently. They may occur at various stages in the growth of the parts — such individuals we call abnormal — we can only mean that there has been an arrested or thwarted development of the parts. For example, in the human female we occasionally find a double vagina — a normal marsupial condition or again we may find the ancient and normal reptilian. In the human male we not infrequently find a condition of the erectile organ which we term hypospadia. Hypospadia is nothing more or less than the normal condition of the erectile organ in the Monotromes. Various other conformations which we call deformations when we find them in man are simply due to the persistence of normal con- ditions of the parts as found in ancestors of the stock. The persistence is due to some check in the evolutionary growth of the human individual. Let us now examine the embryology of the cloacal region in man. Page Nine In the human embryo of fifteen days' growth, the cloaca is well formed. The opening of the urinogenital sinus and the intestine are still confined to the common cham- ber. The cloacal tubercle is prominent and lies in the center of the quadrangle formed by the leg pads, the coccygeal tubercle, and the umbilical cord. Soon, however, changes €t£ctac ^Ureter ■OVi'iu.d'- Cloa£ctl \ rtMettWl Plate 1 . — Evolution of the Cloaca. begin in the cloacal aperture into the definitive anus and the urino-genital sinus or pore. Two folds of the lateral walls of the cloaca grow towards each other, until they meet and coalesce, thus forming the perineum. The proctodaeum breaks through into the lumen of the gut, and the cloaca, as such, is no more. These changes are completed ' oviciujcT . S. Cloacal Plate 2 — Evolution of the Cloaca. Page Ten about the end of the fifth week. I here is, however, a short time during which the human embryo possesses a true cloaca. We have spoken only of the walls of the cloaca. Of course all other structures such as blood-vessels, nerves, and muscles are involved in these transformations, so that in the study of the cloacal region of the adult human we must bear in mind that all the structures have an ancient pedigree. For example the old-time Musculus Sphincter Cloacae is separated into M. sph. Ani. Ext. and M. sph. Urogenitalis. The nervous pudendus breaks up into branches supplying the lower rectum and anus and urethra and erectile organs, each branch receiving an appropriate name in the ter- minology of human anatomy. 1 Tall. Fig. 2. —Tailed Man. Jk- ■ |i\^>V*s'-^- Fio. 3 Cloaca of Rabbit. Fig. 4. — Showng tail extended. {Johns Hopkins Bulletin.) ( ]. M. Sph. Ani. Ext. M. Sph. Cloaca ', "> a. M. bulbo cavernosas j j (a) M. transversus perinei. ^ 2. M. Sph. Urogenit. ' (b) M. urethralis. b. M. ischio cavernosas. In the rabbit for example, we have an intei mediate stage in the separation of the cloacal muscle into its parts — for here the division is not complete and neither sphincter forms a ring — but the two together an open-jointed figure eight. Page Eleven The cloacal muscles are fastened more or less strongly to the coccygeal vertebrae and thus these skeletal parts play an important part in the functionmg ot the cloacal organs. Coccpx.— In the mammals the tail vertebrae range m number from 49 (Mams Macrura) to 3 to 5 as in the anthropoids and man. ^u, , 1 However, in embryonic stages (4 to 1 2 M. M.) man has as many as eight tail segments with the notocord projecting beyond them, mdicatmg a still larger number Fis. 3. — Ventral surface of tail. {Johns Hopkins Bulletin.) Fig. 6. — Showing contracted tail. {Johns Hopkins Bullelin.) in the ancestral stock from which the human species has descended. They form a true external tail. _ , , . , ^ ,. The coccyx is not a stable group of bones but is on the way to disappearance. This is vividly shown by the reduction of the typical external tail of the human embryo so that by the time adult Ufe is reached there is ordinarily no trace of the ex- ternal tail and the internal tail is a mere rudiment attached to the tip of the sacrum. Now and then the external tail is not reduced and we have a genuine tailed man. Pasre Twelve From an examination of the coccygeal bones in the adult we might suppose that they represented the bodies only of the caudal vertebrae but embryology shows us that is not the case. During development they possess membranous, and in the case of the first and second coccygeal vertebrae, cartilaginous neural processes. The articular and transverse processes are incomplete or entirely lacking. Although separate centers are developed for the rib rudiments they do not mature as such. Even the haemal processes appear in membranous form (3rd to 5th month) Fig. 7. — Front- al section of tail, showng the ar- rangement of the muscle fibers (M). a. Place from %vhlch the cross- section represent- ed in Fig. 5 was taken. X3. Fig. 8. — Cross-section through the middle of the tail (Fig. 4, a). M, muscle; M', degenerat- ing muscle; A, artery; A^, nerve; L is placed on the left and R on the right of the appendage. X 9. Fig. 9. — Caudal region of embryo of 14 mm. (No. 144 of Dr. Mall's collec- tion), combined from several sagittal sec- tions. An., anus; Ao., caudal aorta {A. sacralis media); Ca. fil., caudal filament; Ch., notochord; Med., medullary cord; 5. u§., sinus urogenitalis ; V. 32, third coccygeal vertebra; 36, seventh coccygeal vertebra; V. c. i., caudal portion of vena cava inferior (F. sacralis media). X91. to disappear — leaving no trace in the adult. From these bare facts we can recognize the true vertebral nature of the coccygeal bones as vestigeal structures — the remains of com- plete vertebrae in the ancestral stock of the human species. The facts set forth in this brief sketch point unmistakably to the conclusion that the cloacal-coccygeal territory has suffered extensive transformation in its descent to the human condition and to the further conclusion that it is still undergoing change and reduction. The practitioner as well as the surgeon, should have a thorough knowledge of the phylogenetic as well as the ontogenetic history of the region in order to deal intelligently with the normal and abnormal structure and functions of the parts. Page Thirteen CHAPTER II. PERINEUM. ANATOMY. "■-.BUcldt. 1* \ci,n',,-. IU«M. J D.j.itl .,CT cfcl.t;-.! I,mi.<, lu.... I Fig. 10. — Female pelvis and perineum — sagittal section Fig. II. — Male pelvis and perineum — sagittal section (Deaver). (Deaver). Anatomy of the Perineum. Superficial and Deep Tissues of the Perineum. Superficial. Cutaneous. Fat. Fascia, superficial and deep. Blood vessels. Nerves. Lymphatics. Page Fourteen Deep. 1 . Sphincter ani externus. 2. Transversus perinei superficialis. 3. Bulbo cavernosus — or Erector penis and clitoris. 4. Ischia cavernosum. 5. Compressor Urethrae, beneath the triangular Hgaments. Fig. 12. — Superficial fascia of male perineum (Deaver). HE PERINEUM is of recent origin in the history of animal life and found only in mammals, being absent in fish, reptiles and birds and as has been stated, absent in a few mammals, for ex- ample the rabbit. The perineal body lies between the vagina and rectum with the base pointing downward, one inch antero-posterior in diameter and one one-half inches in height, but it may vary in size in individuals of the same kind. In the male it is sup- plied by the internal pudic and inferior hemorrhoidal vessels; while in the female the blood supply is from the iliac artery. It is inhibited by the pudic and small sciatic or pudendal nerves and its lymphatics empty into the inguinal glands. There is no part of the body possessing so great a variety of organs and tissues as the perineum and its intimately asso- ciated structures. Tissues and organs entering into the structure of and most concerned in the forma- Page Fifteen tion of the perineum, anj' one of which by reason of anomaly, disease or injury, may cause subjective symptoms alone or combined, because of insult to one or more branches of the pudic nerve, are classified as follow^s : Perineum Coccyx Urinary Genitalia Rectum Cutaneous Fat Fascia Bone Periostium Glomus-Coccygea Urethra Bladder Ureters Male Penis Prostate Sphincter ani Rectum Sigmoid Muscles Kidneys Cowper's glands Tendons Ligaments Bones Blood vessels Testicles Spermatic ducts Scrotum Nerves Lymphatics Female Vagina Bartholini glands Clitoris Uterus Ovaries Tubes Cutaneous structures reveal as objective the presence of induration, tenderness, color, and subjective such as pain, location, temperature, loss of appetite, general depression and reflected pain, distal to the perineum. Fat is deposited within the integument and external to the superficial fascia and more or less about the muscles. The fascia in the perineum is both superficial and deep. The superficial is a continuation of the superficial fascia of the abdominal wall, thigh and buttocks and extends over the pelvis and scrotum. In the scrotum it is in- termingled with involuntary muscular fibers and forms the dartos muscle which assists in suspending the testicles and corrugating the skin of the scrotum. It also forms the septum of the scrotum which separates the testicles. The fascia over the posterior portion of the perineum fills up the ischio-rectal fossae in the form of two pads of adipose tissue on either side of the rectum and anus, while the fascia of the anterior part of the perineum resembles the same fascia in the groin. The deeper layers are attached to the pudic arch posteriorly to the base of the triangular ligament and in the middle line to the root of the penis (bulbus and corpus spongioseum) and median line of the scrotum. The fascia is continued anteriorly over the spermatic cords to the anterior abdominal wall, and its function is to prevent pus and extravasated urine passing backwards into the ischio rectal fossa or laterally into the thigh. It is directed forward into relation with the scrotum and penis and along the spermatic cord to the anterior abdominal wall. The septum of the scrotum being incomplete, fluid ex- travasated on one side according to Cunningham can pass across the middle line to the opposite half of the perineum and scrotum. The deep fascia of the perineum is only a delicate aponeuroses of the muscles. The superficial perineal arter}) arises in the anterior part of the ischio rectal fossa, pierces the base of the triangular ligament, and divides into long slender branches (scrotales in the male, labiales posteriores in the female) which are continued forward in the urethral triangle, beneath the superficial perineal fascia, to the scrotum. It anastomoses with its fellow of the opposite side, with the transverse perineal and the external pudic arteries, and supplies the muscles and subcutaneous structures of the urethral triangle. The superficial transverse perineal muscle is not always present in the form of a small delicate bundle of fibres arising from the ascending ramus of the ischium and the fascia over it, and forms the base of the triangular ligament. It is directed inwards and Page Sixteen forwards to be inserted into the central point of the perineum and conceals the base of the triangular ligament. The transverse perineal artery is a small branch which arises either from the internal pudic or from its superficial perineal branch. It runs inward along the base of the triangular ligament to the central point of the perineum, where it anastomoses with its -Mijl Fig. 13. — Superficial dissection of the perineum (Kelley), f \y Fig. 14. — Deep dissection of the perineum (Kelley). Page Seventeen fellow on the opposite side, with the superficial perineal branch and with the interior hemor- rhoidal arteries. It supplies the sphincter vaginae, and the anterior fibers of the levator ani. The nerve supply is from the perineal branches of the pudic nerve and its function is to assist the deep transverse perineal in fixing the central tendon of the perineum during the contraction of the bulbo cavernosi. The transverse perinei profundi muscle arises from the ascending ramus of the ischium just below the compressor urethra and is inserted into a median raphe, continues with that of the compressor urethra in the form of two separate bundles of fibers one below and the other behind the compressor urethra. Its function is to fix the central tendon Fig. 15. — Triangular ligament and superficial perineal Fig. 16. — Ischio-rectal fossae and fascia of colles of male interspace of female (Deaver). perineum (Deaver). of the perineum during the contraction of the bulbo cavernosus. Some of its fibers unite with those of the superficial transverse perineal muscle. Its nerve supply is by a branch of the pudic which breaks up into many fine twigs, branches of the fourth sacral nerve. Deep muscles of the pelvic floor. 1. Levator ani. (See rectum.) 2. Obturator internus. 3. Pyriformis. 4. Coccygeus. (See coccyx.) Obturator Internus arises by fleshy fibers on the pelvic aspect of the hip bone and posteriorly opposite the small sciatic notch and, like the obturator externus, is fan-shaped. Page Eighteen 0«ncl * tf ^*<>\ Supflifkial laysr af tr, smaller nerve trunks, which extend to various parts of the body. In the make-up of those that supply both muscles of sensory surfaces (integument or mucous membranes) three sets of fibers are included : 1 . The efferent axones of motor neurones, whose cell bodies are situated in the spinal cord or brain; 2, the af- ferent dentrites of sensory neurones withm the spinal and other sensory gamglia; and 3, the efferent axones of neurones within the sympathetic ganglia that accompany the spinal fibres to the periphery and serve for the innervation of the involuntary mus- cles of the blood vessels, and of the skin and glands. These fibers are grouped mto bundles (funiculi). Each funiculus is surrounded by a definite sheath of connective tis- sue, the perineum, which is directly contmuous with the delicate fibro-elastic tissue prolonged between the individual nerve fibers as the endo neurium. (The perineurium may contain lymph spaces.) When, as is usually the case, the nerve is composed of several funiculi; these are loosely bound together and the entire Bim^l*. A^MrffMl .*B.'.A . Fig. 22. — Diagram of the lumbar and sacral plexuses (Deaver) . Pag-e Thirty-One Fig. 23. — Diagram of sacral perineum (Deaver). trunk so formed is invested by a general envelope, the epineurium, in which course the blood-vessels and lymphatics. The envelopes of the nerve trunks are continued over its branches even into its smallest subdivisions. The last representative being seen on the individual fibre as the sheath of Henle. The perineral and sympathetic nerves, the epithelium of the anus and the imme- diately adjacent parts of the rectum and the epithelium of the vagina and urethra are formed from the ectoderm, while the urinary and generative organs except the epithelium of the urinary bladder and urethra are from the mesoderm. The whole of the vascular and lymphatic systems and connective tissues are also from the mesoderm. From the endoderm are to be found the rectum and epithelium of the urinary bladder. The pudic nerve which supplies the perineum, the uro-genital and rectal tracts is both motor and sensory, and derived from the second, third and fourth sacral nerves. It was split mto many branches when the perineum was formed, which was the beginning of the mammalian period. One branch was for the purpose of supplying the uro-genital, the other the rectal tract and while the nerve has been divided into two branches, their functions are iden- tically the same and their impulses more or less the same, because the central nervous system receives impulses from the two alike. Irritation of one, often produces irritation of the other. Sometimes that of one dominates that of the other profoundly. This is often demonstrated when irritation of the sphincter ani produces greater sexual excitement than irritation of the sexual organs themselves, and vice versa. The pudic nerve and its branches, sometimes vary slightly in their course, but it usually passes forward in the outer wall of the ischio-rectal fossa, divides into the perineal and dorsalis penis nerve and accompanies the pudic artery. Deaver states that nerve terminals like blood vessels and lymphatics, are found in each muscle fibre, that each tissue of the body may be brought under the control of the central nervous system, motor and sensory fibers being alike influenced. T op graphically the relation of the pudic nerve, its branches, lymphatic channels, glands and blood vessels, have been materially changed to meet the requirements incident to the passing from the cloacal to the mammalian type of the lower pelvis. Nerves travel Page Thirty-Two under the endothelia, chiefly in bundles, sometimes in net work and all nerves, blood vessels and lymphatics anastomose that they may be more perfect in function. Among the many branches of the pudic nerve for consideration are the 1. Sacro-coccygeal. 10. Scrotal. 2. Sacral (posterior division). 11. Spermatic ducts. 3. Coccygeal (posterior) . 12. Uterine. 4. Perineal. 13. Vaginal. 5. Penis-clitoris. 14. Fallopian. 6. Urethral. 15. Ovarian, each of which is described 7. Prostatic. with the tissues which they inhibit, 8. Rectal. namely : 9. Testicular. 1. Integument. 7. Glomus Coccygea. 2. Fascia. 8. Coccyx. 3. Muscles. 9. Cowper's glands. 4. Organs. 10. Bartholin glands. 5. Blood vessels. 11. Rectum. 6. Lymphatics. The multiplicity of nerve trunks and fibers supplying the perineal structures and immediate associated organs and structures, must necessarily be the cause of a great variety of symptoms. Nerve centers and nerve fibers are distributed in the walls of all blood and lymph vessels, especially in their deeper layers and are wound around them by the finer nerves. The adventitia and muscularis contain two layers of these small fibers which penetrate the intima. Fig. 24. — The lumbar plexus (Deaver). Ganglion cells are found in the superficial layers of the arteries of organs, but not in their deeper layers. Page Thirty-Three ETIOLOGY. Anomalies, Diseases and Injuries. Anomalies. p^. f Benign. Diseases i a/t i- . (^ Malignant. Injuries. ANOMALIES. Anomalies may be congenital or acquired, primary or secondary, single or multiple, vary in size, shape, length, course and location, or be entirely absent. DISEASES. Benign. Malignant. BENIGN. Neuromata may be congenital or acquired, primary or secondary, single or mul- tiple, vary in size, shape, extent, location, remain quiescent, or continue to grow, but probably never disappear spontaneously. Sy^philis may be congenital or acquired, primary or secondary, single or multiple, acute or chronic, vary in size, shape, location and degree, in one or more nerves or sheaths. Tuberculosis may be primary or secondary, acute or chronic, single or multiple, vary in location and degree, in any nerve or sheath. Cysts may be congenital or acquired, primary or secondary, single or multiple, acute or chronic, in the sheath or body of one or more nerves, contain blood, pus or serum (usually serum), vary in size, location, rate of growth, remain stationary, continue to grow, or disappear spontaneously, without loss of function when the sheath alone is involved. Fistulae may be congenital or acquired, single or multiple, primary or secondary, remain open, close permanently, appear periodically, open upon the cutaneous struc- tures, into the rectum, vagina, urethra, bladder, uterus or peritoneal cavity. MALIGNANT. Carcinomata may be primary or secondary, single or multiple, in any nerve or sheath (usually the sheath). Sarcomata may be primary or secondary, single or multiple, in any nerve or sheath, vary in size, location, rather of growth and usually in the sheath. INJURIES. Lacerations, incisions, punctures, may be the result of accident or design, primary or secondary, single or multiple, vary in extent, location, irregular in form, partial or com- plete, sharply defined, through the perineal body into the urethra, rectum, vagina, bladder or peritoneal cavity. Nerves are subject to injury cuid disease such as inflammation, acute and chronic, simple and infectious, therefore must necessarily play one of the most important roles in the category of symptoms such as are connected with the perineal body and its intimately associated tissues and organs. The resistance of the nerves in this region to disease, would seem greater because of the uro-genital and rectal tracts possessing a greater variety and number of bacteria. Page Thirty-Four This rule should obtain alike with blood vessels and lymphatics which are also the distributors to muscle, fat, fascia, tendons, ligaments, periosteum, bone, cutaneous struc- tures and organs. Nerve sheaths probably have less resistance, but whether they can be inflamed to any degree without more or less irritation to the nerves is uncertain. Nerves like lymphatics and blood vessels undergo degenerative changes due to senility, injury and disease. Then why should such changes not be earher in the perineal region which is inhabited by so many infectious bacteria? Is it not possible to have such changes appear locally and earlier in this region be- cause of their presence? If so, the manifestations would be atrophy, resulting in pain, discomfort, loss of function or formation of concretions and new growth, such as are found to exist with incontinence, calculi and prostatic hypertrophy. SYMPTOMS. Local. Tenderness is elicited by the sense of touch which may cause pain varying in degree when a nerve is injured or pathologic. A nerve may be sensitive with or without pressure at the point of lesion and though a nerve throughout its course may be sensitive and painful when its distal libers are primarily involved, the pain and sensitiveness may be limited to such an area or general nervous irritability may exist with severe pain, con- stant or periodic in character throughout the pelvis and thighs, especially the genito-urinary and rectal tracts. Severe pain may be associated with, or followed by chill, headache, shock and per- spiration. Pag-e Thirty-Five CHAPTER VI. LYMPHATICS. ANATOMY. N ATOMY of L^mph-Vesseh. The structure of the lymphatics is very similar to that of the veins, the largest ones having the three coats, mtima. media, and adventitia. The lymphatics aris- ing from any network come together to form larger vessels, just as do veins, but they are more uniform in caliber, while a lymph vessel may be the same size as a vein at its origin, it will be much smaller than the vein at its termination. L))mphatics are numerous and generally distributed through- out the perineal structures and organs, and their function probably more important during the period of gestation. ETIOLOGY. Anomalies, Diseases and Injuries. Anomalies. f Benign. \ Malignant. Injuries. ANOMALIES. Anomalies may be congenital or acquired, primary or secondary, single or multiple, vary in size, length, location and number of glands and channels or entirely absent. D iseases DISEASES. Benign. Malignant. BENIGN. Lymphomala may be congenital or acquired, primary or secondary, single or mul- tiple, in suF>erficial or deep structures, vary in size, shape, disappear, remain quiescent or continue to enlarge. Tuberculosis may be primary or secondary, acute or chronic, single or multiple, vary in size, extent and location, remain quiescent, continue to grow, or disappear spon- taneously. Syphilis may be congenital or acquired, primary or secondary, acute or chronic, single or multiple, vary in size, extent and location, remain quiescent, continue to grow, or disappear spontaneously. C^sts may be congenital or acquired, primary or secondary, acute or chronic, single or multiple, vary in size, shape and location, contain blood, pus or serum, rupture ex- ternally, through the perineal tissues, internally into the rectum, vagina, urethra, bladder, uterus, or peritoneal cavity. Page Thirty-Six Fig. 25. — Lymphatics of the blad- der in the new-born infant (Cuneo- Marcille). a. External iliac gland (external chain). b. External iliac gland (middle cham). c. External iliac gland (internal chain), d. Deep in- guinal glands. e. Left juxta-aortic gland. /. Gland of the promontory. §. Lateral vesical glands, h. Prae- vesical glands. Fig. 27. — Lymphatics of the pros- tate (Cuneo and Marcille). Fig. 26. — Iliopelvic glands (Cuneo- and Marcille). Fig. 28. — Scheme of the ileo-pelvic glands (Cuneo and Marcille). MALIGNANT. Carcinomata may be primary or secondary, single or multiple, in any of the lym- phatic structures within the perineal body. Sarcomata may be primary or secondary, single or multiple (usually single) , in any of the lymphatic structures of the perineal body. INJURIES. Incisions, Lacerations, Contusions, are acquired by accident or design, primary or secondary, single or multiple, through the perineal body, rectum, or vagina, and vary in degree. Pag-e Thirty-Seven SYMPTOMS. L})mphatic duds and channels supplying the perineum subject to anomalies, diseases and injuries, offer symptoms which are manifested by enlargement, tenderness, redness, pain, chill, temperature, nausea, headache and vomiting, and the presence of serum, Tblood or pus, depending upon the degree of infection which may be acute or chronic, primary or secondary. Pain is not always localized because it may be reflected to adjacent healthy tissues and may also be influenced by the degree of mfection. Induration is a determining factor in the symptomatology of all structures even to the slightest degree, but its importance increases with degree especially in lymphatic struc- tures. Rarely are the lymphatics of the inguinal or pelvic regions unpalpable. This en- largement of the lymph nodes is associated with tenderness and pain which necessarily causes nervous exhaustion and a symptom complex that space to describe would fill volumes. Again referred pain or reflexes to the knee, heel and back are marked. The necessary combined intoxication with a slight febrile rise has frequently associated head- aches, general malaise, loss of appetite, and a general weakness, all of which causes in- validism. Ulcers of the rectal wall may cause a marked lymphangitis and enlarged lymph nodes. Vascular influences upon the lymphatics are so slight in the begmning that they cannot be recognized, but as the pulse rate increases and becomes uniformily rapid and feeble, irregular or intermittent, from any cause, the lymph ducts and glands may justly be con- sidered inactive. // the temperature is high, lymphatic involvement is at once considered, though this does not always obtain. Tenderness is one of the first memifestations of glandular affections, and the degree of pain increases with the amount of involvement until it becomes a distinct characteristic. It may be local or general, acute or chronic, without local or general disturbances, color, infection, or induration, but these are exceptions. Lymphatic glands being without many sensory nerve fibers must necessarily be without much sensation, and for this reason direct pressure upon the glands does not elicit much pain; it is the surrounding structure, when involved, the nerve supply of which is greater, where pain is produced. Normal glands are not sensitive to touch, but when infected, chill followed by headache and febrile, disturbances may vary in degree and the temperature may be local or general. Headache may, however, result from the slightest degree of infection, without other symptoms even to the degree of severe cephalalgia, but this seldom occurs without the more severe forms of infection. When they occur, nausea and vomiting and even shock may be present and vary in degree. Page Thirty-Eight CHAPTER VII. GLOMUS COCCYGEA. ANATOMY. ISTORY. — A small reddish-yellow body situated about the tip of the coccyx was first discovered by Luschka, 1 859, since which time it has been known as Luschka's gland though it has long since been discovered not to be a gland because it does not possess glandular tissue. Walker, 1904, suggested that this small body might be a gland of internal secretion but it can not perform such a func- tion if it does not possess glandular tissue. Much has been written pertaining to the anatomy, func- tion and pathology of this most interesting mass of cells without revealing anything definite concerning its physiology. Until such a discovery, continued interest will be manifested with this in view. It is a vascular plexus, a rete mirahele and not a gland. The human coccygeal gland (so-called) or Glomus coccygea, is a reduction product due to the decrease in size of the caudal region. In man it usually is found as one ovoid body attached to the arteria sacrahs media, lying on or near the ventral side of the distal end of the coccyx. Sometimes it is separated into several pieces or distinct glomeruli. It is descended from the glomeruli caudales of the lower mammals. In the adult human it is an arterio-venous plexus of varying complexity and size. The plexus takes the form of a nodule inclosed in a fibrous sheath. The vessels com- posing it may be divided into the afferent artery, the efferent vein and the connecting anastomosing channels. Although sparsely innervated by the sympathetic it has no special relation thereto. Besides the sheath and the vascular channels, the principal his- tological element which forms a considerable part of its mass, are the endotheloid cells, which are numerous and appear to be derived from the transformed muscle cells of the arterial walls and which remain intim.ately associated with the walls of the vascular channels. Other than these, there are no structural elements entering into the make-up of this organ. Non-striated muscle cells are distributed throughout the stroma. It is not known what function the glomus serves in the human physiology. Phylogeneticall]) the human Glomus coccygea is the descendant of the numerous Glomeruli caudales of the lower mammals, which, due to the shortening of the tail, have become condensed into the usually single and much larger Glomus coccygea of man. The s})mpathetic nerve trunk accompanying the A. sacralis media is often enmeshed in the substance of the glomus, but this is purely a mechanical relation as the innervation of the tissues of the glomus is not in such cases increased. However, single and clusters of "nerve end" bodies somewhat resembling Paccinian bodies, are found in juxtaposition to the glomus. The glomus occurs as one or man^ nodules lying near the anterior aspect of the tip of the coccyx. If often appears pedunculate owing to the elongation of the artery and vein connecting it with the median sacral vessels. Page Thirty-Nine The glomus develops within a mass of embryonic cells, by the branching of the median artery and vein, and first appears caudad of the actual tip of the last coccygeal segmen^. ^^^ ^^^ ^^^ Glomeruli Caudales exist as a chain of knots extending fronvthe 8th or the 9th caudal vertebra, caudad, to the tip of the tail increasmg m size backward, the largest glomus occurring at the tip of the tail. The anatomical and histological struc- ture is similar to that of man. • i -ru In the Macacus monkey as many as ten glomeruli occur in one animal. 1 hey are all closely attached to the A. sacralis (caudalis) media and increase in size from the Fig. 29.— Tail of Macacus Monkey, showing a Glomus at each bony segment (Schumacher). anterior caudal vertebrae caudad to the tip of the tail. They usually occur one in each segment They constitute a series of segmental plexuses inserted between the artery and the vein and afford a direct connection between the two without the mediation of capil- laries. The largest of them is only a few millimeters in length. Glomerulus cocc^geus. Glomeruli caudales. . r i i i i . l Among mammals the glomeruli occur in that section of the tail where the vertebrae lose their ventral arches but still retain the haemal arches. Page Forty Glomeruli have been found in Beginning at the Macacus cynomolgus — common Macacus. Macacus rhesus Felis catus cat 8th caudal vertebra Canis vulpes fox Canis familiaris dog 8th to 9th caudal vertebra Lutra vulgaris otter 1 2th caudal vertebra Scuirus vulgaris squirrel 1 0th caudal vertebra Lepus canniculus rabbit Mus rattus rat, mouse 1 4th caudal vertebra Sus scropa pig Bos taurus ox Equus caballus horse Cynocephalus hamadryas Pavin. DESCRIPTION OF FIGURES. S. V. Schumacher-GIomus Coccygea and Glomeri Caudales. 1. Section of Gl. coccygeum of executed criminal. A., anastomosing vessels with epitheloid wall. M., muscle bundle entering Glomus. S., con. tissue stroma. V., outgoing vein. X70. 2. Closed anast. vessel of Gl. c. of 3-year-old child. E., endothel EZ. epitheloid cells. S., stroma. X 460. 3. Anast. vessels of Gl. c. executed g P. perimysium internum inclosing Epitheloid cells. E. S. stroma. X 460. 4. Transition of artery with anast. vessel in Gl. c. new born babe. M., nonstriated muscles and transition stages into epitheloid cells eZ. E., endothil X460. 5. Transition of anast. vessels into vein of Gl. c. 22-year-old man, shows that epitheloid cells disappear as vein is approached X460. 6. Same as 5 from 5-year-old child X460. 7. Same as 5 and 6 from executed woman X460. 8. Three nerve end bodies lying near Gl. c. lumen foetus 34 cm. long. X460. 9. Same as 8 from new born. L., lammellated bodies. K., capsule. G., location of Gl. c. X 170. 10. Anlage of Gl. c. human emb. 52 cm. long. A., art. sacralis media showing thickening of media. M., cells of media becoming epitheloid. V., vein. E., endothel. X460. 11. Section Gl. caudale Cynocephalus hamadryas. A. C. branch of art. cm. entering Gl. c. 12. Artery of Gl. c. of dog. Ac. wall of art caudalis media, showing muscular layers. X70. 13. Section of anastometic branch of vessel of Gl. c. of Cynocephalus hamadryas. E., endothel. I h. inner longit. muscle. Z. M., circular muscle. A 1., outer long muscle. S., stroma. X460. 14. Section anastimolic vessel of dog. M., epitheloid muscle cells. E., endothel. S., stroma. X460. 15. Section anaslomol. vessel Gl. c. executed woman. E., endothel. E z. Epitheloid cells. S., stroma. X460. 16. Two small Gl. c. 55-year-old woman, artery red, vein blue, anastomotic vessels violet. X57. 17. Vessels of tail of Macacus rhesus ventral vein. A c m., arteria caudalis media. V c m.. Vena caudalis media. V c 1. Vena caudalis media. A v.. Anastomotic veins between V media and V lateralis. G., Glomeruli caudales. 18. Vessels from distal section tail of Macacus rhesus. G., large Glomerulus. K., Small one. 1. J. H. Jakobsson. Glomus coccygea. X40. Sagittal section embryo 1.8 cm. long. ar. arterio sacralis media. bl. glomus. bp. vascular papila. c. central canal. ccg. glomus coccygea. ch. chorda dorsalis. d. gut. ep. epidermis. ft. fllum terminale. kaps. capsule of stroma. m. non-striated muscle. mv. medullary tube. n. nerve. par. cartilage parenchyma. str. stroma. su. caudal appendage. sy. sympathetic anlage. • tb. terminal vesicle of nerve tube. Paae Forty-One -:y <;»Q>'b >. /I 5^ '.^■^.. -r-^ ;-^r Fig. 30. Page Forty-Two ,;-.-i>;^ f3i«* Fig. 31. Fig. 32. Page Forty-Three ■1 \ .*' ' Fig. 33. Fig. 34. Fig. 35. Page Forty-Four 2. X20. Sagittal section embryo 7.5 cm. long 3. Xl5. Sagittal section embryo 1.5 cm. long 4. X 15. Sagittal section embryo 6 cm. long. 5. X65. Transverse section embryo 8.1 cm. long. 6. X90. Section of Glomus coccygea. 7. X3(X). Sagittal section of Glomus and med. tube. 8. X300. Transverse section of Glomus. 9. X 55. Transverse section of Glomus of adult. 10. X350. Transverse section of Glomus of adult. Page Forty-Five Fig. I. Fig- 3 Fig. 36. Page Forty-Six 7*i?v Fig. 4. Fig. 5- -56 Fig. 37. Page Foi-ty-Seven Fig- 7- ^vi^' M. j ., 3, s, ii, 1-16, 1 pi., 1867. Sertoli, E. Ceniralb. f. d. med. IVissensch., Berlin, v. 449, 1867. Brezzi, D. Cicr. di. med. mil. Firenze, xv, 3-9, 1867. Monod. Une piece anatomique provenent d'un enfant ne avec une queue. Bull. Soc. d'anthrop., Paris, 2, s, IV, 407-411, 1869. Philipeaux, J. M. Experieces sur la glande de croupion faite sur le canard. Comp,. rend. Soc. biol, Paris, 5, s, iv, 49-52. 1874. Sayre. Congenital Malformation of Coccyx, Operation. Med. Rec, New York, ix, 242, 1874. Vinogradof, K. Malformation in the Region of the Coccyx. /. J/pa normal i patrol, gistologii, S. Petersburg, x, 506-524, 1876. Ecker, A. Ueber gewisse Ueberbleibsel embryonaler Formen in der Steissbeingegend beim un- geborenen, neugeborenen und erwachsenen Menschen. Arch. f. Anihrop., Braunschweig, xi, 281-284, 1878-9. Bastian. Ueber geschwantzte Menschen im indischen Archipel. Verhandl. d. Berl. Cesellsch. f. Anthrop.. BerUn. 412, 1879. Bartels, M. Arch. f. Anthrop., Braunschweig, xiii, 1-41, 1 pi. 1880-81. MacDonald, A. Backward Projection of Coccyx with Anchylosis of Sacro-Coccygeal Joint. Edinh. M. ]., xxxi, 318-320, 1885-86. Gruber, W. Ein seltener Curvator Coccygis Accessorius bei gewissen Menschen Homolog deni constanten Depressor Candae Longus bei gewissen Saugethieren vorher nicht gesehen. Arch. f. path. Anal, Berlin, cix. 1-4, 1887. Jacobi, F. H. Arch. f. Anal. u. EntiDcklngsgesch., Leipzig, 353-364, 1888. Fry, H. D. The Function of the Coccyx in the Mechanism of Labor. Am. J. Ohst., New York, xxi, 1257-1265, 1888. Farr, F. W. Case of Rigid Coccyx. Guy's Hosp. Gaz., London, ns, iii, 173, 1889. Torngren, A. Ett fall af kongenitalt coccyxkystom. Klns^a lal( salls}( handl., Helsingsfors, xxxii, 388-394, 1 pi., 1890. Fere, C. Une anomalie du coccyx chez un epileptique. A^. inconog. de la Salpetriere, Paris, v. 89-91, 1 phot. 1892. Biancha. Sulla interoretazione morfologica della prima vertebra coccigea nell'uomo. R. Accad. D. fisioerit. in Siena, Proc-verb, 9, 1895. Hlrschberg, R. Un cas se mal perforant coccygien. Rev. neurol, Paris xii, 792, 1904. Lindquist, S. Some Remarks on Obstetrical Coccyx Ankylosis. Page Pifty-Six Fig. 43. — Posterior view of coccyx of Chimpanzee (Pat Roony the First, Cincinnati Zoo). Nord. Tidsskr. f. Terpi, Kobenh., vii, 103, 129, 1908-9. Sappy. On the Lymphatic System. A Volume Frequently Referred to and Freely Quoted. Hyrtl. Sitzungsbericht der Wiener Accad. Moth, watern. Kl. Bd. liii. Rosenberg. Morphol. Jahrbuch, Bd. L. Page Fifty-Seven Fig. 44. — Lateral View of the Coccyx of Chimpanzee (Pat Roony the First, Cincinnati Zoo). ETIOLOGY. Anomalies, Diseases and Injuries. r Anomalies. Diseases < Benign. [^ Malignant. I Fractures. Injuries - Ankylosis. f Luxations. Page Fifty-Eight ANOMALIES. Anterior v.ev Antfirio Postener Curve LiUra^l view Personal Cases of Abnormalities. (Ayers Arrist.) Anterior viev tjlrcmi Antciior Lutve llm Sei^mciiUd. Coccyx. A-ntcrior viev An Attcmpl. J>1 Seimcntalio Fig. 45. Anomalies of the coccyx being of such a diversity, especially in shape, must play a certain role in general symptomology. Any variation from normal to total absence must be determined before considering the subject in a general way. This may be done by palpation with the finger except in a few instances where segments are wanting, then it is difficult to define the hmitations of the lower portion of the sacrum. The sacrococcygeal line may never be determined with the existence of such a condition. Congenital def ects of the coccyx 1. Length. 2. Diameter. Shape. 4. Flexibility. D. Ankylosis. 6. Absence. Paee Fifty-Nine Length may vary from long to short. When long it may be due to increased length of the segments or sacrum, or both. Sometimes though infrequent, the segments may be increased to six or more in number. Excessive length more frequently causes inconveniences than excessive shorteess, which is due to the segments being diminished in length or number. Diameters of the segments of the coccyx vary considerably from large to small. Any one or all may be excessive in the lateral or anterior-posterior measurements. Shape may be regular or irregular, smooth or rough, sharp or blunt on the edges, or at the point. Flexibility varies in degree and direction. It may be unilateral, bilateral, anterior, posterior or movable in all directions, and occasionally displaced downward by traction, a type referred to as floating coccyx. Ankylosis may be partial or complete, straight, angular or curved laterally, anterior or posteriorly. Absence. Several instances have been cited where the coccyx was congenitally Wcuiting in part or its entirety, thus indicating that it is on the road to disappearance and that it is not an anatomic or physiologic necessity. Anomalies. Post. Ne-w York M. /.. xxx, 517, 1879. Imlach. Brh. Gpnec. /., London, i, 319, 1885. Whitehead. Lancet, London, ii, I 12, 1886. Odell. Lancet, London, 1088, 1887. Evans. Phila. Med. Times, xviii, 35, 1887-88. Dunn. Cu^'s Hosp. Rep., London, xxx, 191, 1889. Darrach. Boston M. & S. J., xxviii, 36, 1893. DISEASES. Benign. Malignant. Neoplasms niop be congenital or acquired, of many kinds and varieties, primary or secondary, vary in size, shape, number cind location, develop in any direction, involve by extension any of the soft or bony structures of the lower pelvis and perineum. History. Zeddler, 1 834, reported a case of steatoma of the coccyx, the first of its kind to be recorded. Heschel, 1 860, reported simple hypertrophy, and Clemantais, 1 883, one of simple growth with fistulae. Erass, 1883, a congenital tumor, Jewett, 1884, an angioma. Barber, 1910, a tumor in the coccygeal region of an infant six months old, and Bod, 1910, a ccLse of hernia of the spinal cord in the coccygeal region operated upon by Zenenk's method. BENIGN. Benign diseases of the coccyx may be congenital or acquired, primary or secondary, acute or chronic, remain small or assume a considerable size, of many varieties, and asso- ciated with angioma of the spinal cord and various other types of new growth to com- plicate their differentiation. Coccygitis may be the result of injury or disease of the coccyx, tissues overlying or indirectly associated with the coccyx. Chondromata may be congenital or acquired, primary or secondary, single, vary in size, shape, location, usually in the lower segments, slow or rapid in growth, remain quiescent, increase in size or disappear spontaneously, though this seldom occurs. Osteomata may be congenital or acquired, primary or secondary, single or multiple, originate in any one or more of the segments or their periosteum and vary in size. The Page Sixty secondary growths extend from the sacrum and the primary growth of the coccyx may in turn become secondary in the sacrum. Degeneration of one or all segments of the coccyx may be in the form of caries or necrosis due to tuberculosis (Caubet) syphilis, osteomolitis (Monnier) or injury. Kuss, 1909, reports a case of retro-anal fistula due to tuberculosis of the segments of the coccyx. Such degeneration may be secondary to disease of the sacrum or the soft tissues im- mediately surrounding the coccyx. Tubercular degeneration may be acute or chronic, mvolve one or more segments, primary or secondary rupture into the rectal cavity, externally through the cutaneous struc- tures, or extend into the sacrum and rupture in any direction. Syphilitic degeneration may be congenital or acquired, primary or secondary, acute or chronic, occasionally destroy the coccyx without manifestations elsewhere, or the over- lying soft structures posteriorly, laterally or anteriorly into the rectal cavity. Osteomyelitic degeneration rarely occurs in the coccyx, but when it does occur, it is subject to the same rules concerning the destruction of its overlying soft structures. It, too, may be primary or secondary to the sacrum, which it usually involves when primary. Etiology. Cummenus, A. H. Misc. Acad. net. curios, 1672, Lips, el Francof, iii, 1672, 209. Faye, F. C. Norsk- Mag. f. Laegevidensk, Christiana, ii, 591-593, 1848. Boyer, L. Rev. med. chir., Paris, xi, 246, 1852. Cleaveland, C. H. New Jersey M. Reporter, Burlington, vi, 171-1853. Hersher, D. W. Boston M. & S. /., liv, 516, 1856. Roeser. Luxalio ossis coccygis. Memorabillien, Beilbr. 1856, i, No. 18, 1, also (Abstr.) Noliz. f. prakl. Aerzte, etc., Berlin, 1858, n, F. i, 415, also Trans. Brit. & For. M. Chir. R., London, xx, 544, 1857. Uhde, C. W. F. Fraclura. Deutsche Klinik, Berlin, ix, 108, 1857. Bonnefont. Luxation. Union Med., Paris, 2, s, i. 136-138, 1859. Mouret. Rec. de. mem. de. med. mil., 3, s, i, 350-376, 1859. Faye, F. C. Norsk J^og. f. Laegevidensk, Christiana, xv, 137-146, 1861. Barrt de la Faille, J. Nederl. Tijdschr. v. Heel-en Verlosk, Utrecht, xxi, 537-541, 1861-2. Sky, Lancet, London, ii, 326, 1861. Belts. Memorabil., Heiibronn, x, 58, 1865. Warren, J. M. Injuries. In his Surg. Obs., Boston, 593-597, 1867. Macdonald, W. Glasgow M. /., 3, s, li, 171-173, 1867-8. Denuce, P. Des fistules ossifluentes de la region anale. De la resection du coccyx et des ses indications, Paris, 1874. Bellamy, W. J. H. Nort. Car. M. /., Wilmington, 1, 151, 1878. Blockwood. Proc. Phila. Med. Soc, ii, 56, 1880. Couraud, J. Contribution a I'etude des depressions fistules congenitales cutanees et kystes dermoids de la region sacrococcygienne, Paris, 1883. JoUv, W. J. Med. Rec, New York, xxxii, 762, 1887. Baiiey, W. W. J. Med. Soc, A.kansas, Little Rock, iv, 108, 1893-4. Jackson, Pausdale. Lancet, London, i, 209, 1896. Le Ray. Echo Med., Toulouse, 2, s, x, 61, 1896. Dieulafe and Giles. Toulouse Med., 2, s, v, 248-250, 1903. Necrosis. Shidsgaard Hosp. Tid. Kjobenh., vi, 121, 1863. Braune, W. Monaischr. f. Cehurtsk. u. Frauenkr., Berlin, xxiv, 1-10, 1 pi, 1864. Dunn, L. A. Guys Hosp. Rep., London, 3, s, xxxi, 191-196, 1889. Darrah, R. E. A. Boston M. & S. /., cxxviii, 36-38, 1893. Raymond, F. N. Iconog. de la Salpetriere, Paris, viii, 65-106, 1 pi., 1895. Monmer, L. Rev. d'orthrop.. Pans, xxx, 201-396, 1904, xxxi, 643, 1905. Villemin, P. Tubercul. inf., Paris, ix, 97-100, 1906. Marro, G. Arch, di pschiat. Torino, xxviii, 445-454, 1 pi., 1907. Kuss, G. Bull, el mem. soc. anal., Paris, Ixxxiv, 645, 1909. Cysts may be congenital or acquired, primary or secondary, acute or chronic, single or multiple. When primary they originate from the articulating surfaces of the long segments, while those secondary may originate from the sacrum or the soft structures sur- rounding the coccyx. They may be tubercular, syphihtic, dermoid or hydatid, and con- tain serum, blood, pus, echinococci, or epithelial structures such as hair, teeth and some- Page Sixty-One times bone known as teratoma or dermoid. Either of these forms may be congenital and all with the exception of the dermoid variety may be acquired. Cysts may result from degeneration of osteomata or other benign or malignant neo- plasms. Indeed, these are quite frequently their origin. They may rupture externally, into the vagina, uterus, urethra, bladder, peritoneal or rectal cavity, usually into the rectum, remain open indefinitely to close spontaneously, or continue to form a permanent fistulous tract. History. Fistulae have been reported by Macdonald, 1867, Denuce, 1874, Couraud, 1883, and Jolly, 1887, the last named having seen a case in which the coccyx passed per anum, after having been subjected to fracture. Gehrung, I 888, reported a case of dislocation of the coccyx and Bailey, 1 893, one of fracture in \vhich an incorrect diagnosis was made. Le Roy, 1 896, one of coccygeal fistula, and GiUes, 1 903, of retro-expulsion of the coccyx. Sinuses in the overlying soft structures almost invariably result from any injury or disease of the coccyx. Fistulae may be congenital or acquired, primary or secondary, single or multiple, acute or chronic, connect any part of the uro-genital, peritoneal or rectal tracts or coccyx, their strutcures, or the structures of the perineum. The fluids passing through these fistulous tracts may be fecal, urinary, seminal, peritoneal, blood, pus or serum, from the uterine cavity, any bony tissue about or near the pelvis, or from a lesion within the soft structures of the perineum independently. MALIGNANT. Sarcomata. Carcinomata. Malignant Neoplasms of the coccyx aie numerous in variety and probably grow as rapidly as when other tissues or organs are similarly affected. History. Heretaux, 1882, reported a case of sarcoma of the coccyx and Raingeard, 1884, observed a case of sarcoma originating at the sacro-coccygeal junction with complete degeneration of the coccyx. Many such cases have been observed before and since the time of these reports. Sarcomata may occur in many varieties, develop slowly or rapidly and become of considerable sizes. They may be primary or secondary, involve the sacrum or secondary to the sacrum, originate in the segments, their synovial linings, periostial or other soft tissue coverings and in the form of teratomata. Carcmomata are probably of rare occurrence in the coccyx but as its overlying soft structures are frequently its origin it is necessary to consider it especially in secondary involvement. 1 hey may be primary or secondary, vary in size, shap)e and location. Neoplasms. Zedler. Cen. San. Ber. v. Schlesien, fur das Jahr. 1832, Breslau. 334, 1834. Lepellepetries. Lancet, London, 4-11, 158, 1883. Stanley. Med.-Chir. Trans., London, xxiv, 1841. Chibb. Med. Times, London, xvi, 274, 1874. Johnson. Lancet, London, ii, 35, 1847. Herschl, I. Oesterr. Ztschr. f. prakl. Heilk.. Wien, vi, 221-224, 1860. Baune. Das Doppelbild und Geschw. d. Krenzbein Geg., Leipzig, 1862, Ang. Steissbeingeschen. Monatschrift filr Ceburishilfe und Frauen}(ran}(heiten, xxiv, 1864. Ellis. Boston M. & S. J., ixxii, 417, 1865. Buck. Coccyx Cysts. l\. Y. Med. Record, 96, 1866. Holmes. Brit. M. J., London, 315, 1867. Mason. Trans. Path. Sac, London, xxv, 194, 1874-5. Cabot. Sacral Teratom. Boston M. & S. J., xcviii, 112, 1878. De Rothschild. Bull. Soc. d'obst., Paris, ii, 112, 1878. Shattuck. Trans. Path. Soc, London, xxiv, 197, 1880-1. McDowell. Med. Press & CiVc, London, xxxiii, 271, 1882. Hertaux, /. de Vouesl. Nantes, xvi, 377, 1882. Paae Sixtv-Two Chenantais. /. de med. de I'ouesl, N antes, xvii, 457, 1883. Eross, G. Orvosi helil, Budapest, xxxix, 973-979, 1883. Jewetf, F. A. N. A^en; York M. /., xxxix. 612, 1884. Raingaard. /. de Med. de I'ouesl, Nantes, xviii, 281-284, 1884. Favel & Jackson, Lancet, London, i, 843, 1885. Leriche. Cong, franc, de. chir., proc-verb., 1886, Paris ii, 519-525, 1887. Owen. Trans. Path. Soc, London, xxxi, 425-7, 1887-8. McCarthy. Lancet, London, i, 920, 1888. Bowlby. Coccygeal Tumors. Brit. M. J., London, i, 663, 1890. Vincent, E. Mem. el compl. rend. soc. d. sc. med. de Lyon, (18S9) xxix, pt. 2, 180-182, 1890. Borst. Die angie Geschwulst der sacr. Region. Centralb. f. Allg. path. u. path., Jena, ix, 449, 1896. Jahr. d. Basn. Herzegovina, landespil in Sarjeno, 1894-96, 787-90, Wien, 1898. Alezais-Peyron. Compl. rend. Soc. de. Biol, Paris Ixvi, 1121, 1909. Barbarin, P. Paris Chirurg., ii, 229-231, 1910. Brod, I. S. Khirurgia. Mosff., xxviii, 31-33, 1910. INJURIES. Fractures. Injuries of this character in the male are usually caused by direct force applied from below or behind, while in the female, the pressure from the foetal head during delivery is an added cause. History. Fractures of the coccyx have been of many varieties and due to many causes. Cummenus, 1672, reported on its luxations, Faye, 1848, fracture, Boyer, 1852, fracture with reduction, and Cleaveland, 1853. on fracture due to difficult labor. Herschey, 1856, observed a case of simple exfoliation of the coccyx, Mouret, 1859, an incomplete luxation, Faye, 1861, one of fracture resulting in ankylosis, and Bellamy, 1878, one of gunshot wound of the coccyx and perforation of the rectum. Fractures of the coccyx are due to injury or disease, and are classed as acquired causes. They too will produce sjanptoms which are associated with the uro-genital and rectal tracts tractures. a. Simple. b. Compound. c. Comminuted. d. Compound comminuted. ' Simple fractures may occur in one or more segments, transverse, oblique, lateral or perpendicular, or they may be associated with fractures of the sacrum. Simple fractures of the coccyx may be associated with a simple fracture of the sacrum, such a case having been observed in a woman 38 years of age as the result of a fall, the force of which was directed perpendicularly through the sacrum from below. This is the only case found recorded. The fracture apparently was transverse through the sacrum, while that of the coccyx was transverse through the articulating surfaces of the third and fourth segments. The pain resulting from the fracture was excruciating and only relieved by excision of the coccyx by local anesthesia. The pain and tenderness, however, continued for several months thereafter in the region of the sacral fracture. Compound fractures may occur in one or more segments, even to being associated with that of the sacrum, and the laceration of soft tissue, extend laterally, posteriorly through the cutaneous structures, or anteriorly through the wall of the rectum. Comminuted Fractures may involve one or more segments alone or be associated with that of the sacrum. Compound Comminuted Fractures may occur in one or more segments alone, or with that of the sacrum and involve the soft structures laterally, posteriorly, or anteriorly through the wall of the rectum. Either of the foregoing fractures may result in infection, and abscess which may Pag-e Sixty-Three rupture into the bladder, uterine or peritoneal cavity, the vagina or rectum, which is the most common course. Ank})losis may be of any degree from slight movement to complete mobility, and in many positions from straight to curve, or angular, laterally, emteriorly or posteriorly. Flexibility is more frequent in the female and ankylosis in the male. The latter probably being due to hardship and a smaller pelvis. Ankylosis is also produced by prolonged sitting posture. Luxations may occur in one or all joints, even to complete separation from the coccyx, anteriorly, posteriorly or laterally, and such conditions are very much inclined to cause considerable irritation and pain. Their degree being influenced by occupation. SYMPTOMS. {Coccyalgia. Coccygalgia. Coccygodynia. The coccyx having not escaped the influences wrought by the anatomical changes in the perineum, should be considered an important factor in the causation of symp- toms and surgical conditions, which are many times extremely complex in character and their relation to the rectal and uro-genital systems. Sensory impulses pass upward, motor impulses downward, indicating that the coccyx plays the role of a disturber more than that of the disturbed. It is an offender, not defender, therefore must be the cause of complex symptoms especially because of its relations, attachments and exposed position. The congenital or acquired absence of the coccyx does not interfere in the least with the function of muscular fibers which are attached to it normally. The periosteum enveloping the coccyx may be primarily or secondarily affected by disease or injury or their consequences and for this reason must be considered independently in the causation of symptoms, though it may not have received proper recognition. History. Pain neuralgic in character, in the coccyx, has been recognized for many years but little was written about it until after Nott, 1 844, of New Orleans, delivered an address upon the subject. Since then much has been said about the coccyx being a causa- tive factor. Scanzoni, 1861, Jenks, 1873, Worms, 1876, and Rockwell, 1877, each reported a case of pain due to injury. Hale, 1 888, also had one due to disease of the segments. Goodall, 1883, Sutton, 1888, Montgomery, 1895, Fletcher, 1897, and Courtois- Suffit, 1 904, and 1910, reported coccygodynia of traumatic origin. Many others have contributed most excellently to the sum total of our knowledge of this subject. Pain and tenderness are probably the most common symptoms and they may be due to many causes direct or indirect, primary or secondary, such as injury or disease of the coccyx or nerves associated with it. It may be mild or severe, acute or chronic, constant or periodic, and appear at any age, in either sex, but more frequent in the female before fifty years of age. It is rare in the very young and old, and any degree of pain may exist with or without infection of any character or degree and when a deformed coccyx pulls on muscular fibers that are out of their normal position. The coccyx when diseased or deformed quite frequently produces irritation of the rectal and urinary system in part or in general, and frequent urination and defecation as- sociated with or without pain or tenesmus and general nervousness are quite commonly associated with its abnormal conditions. Tenderness is usually pre-ent with all and any irritation resulting from such a condition may result in infection and abscess with all of their sequellae at any point within the genito-urinary or rectal tracts. Page Sixty-Pour Rcclal or uro-gcnital pathology of any kind or degree may produce coccyalgia vary- ing in severity and resuil in general or sexual neurasthenia, especially when severe in either the acute or chronic form. COCCYALGIA. Bibliography. Coccyalgia. Nott. Aem Oilcans M. /.. i, 1844. von Scanzoni, F. W. Ueber coccygodyn. IVurzburg mcd. Zbcbr., 820, 1861. von Scanzoni. Ueber coccydynie, Wiirzburg, 1861. Gosselin. Coccyodynie. Caz. J. hop., Paris, xxxiv, 489, 1861. Faye, F. C. Coccyodynie Resulting from Fracture. Norsf;. Mag. f. Laegc\>idensk< Christiana, xv, 137-146. 1861. von Frangui. Ueber Coccygodynie. McmoTabilien, Heidelberg, viii, 109, 1862. von Scanzoni. Memorabilien, Heilbronn, vii, 40, 1862. von Franque, A. Memorjbilien, Heilbionn, vii, 105-107, 1863. Am. I. ObsL, New York. 243, 1869. Coccyigodinia. Barth. Malta., i-iii, 213-219, 1871-5. Jenks. E. W. Tr. M. Soc, Michigan, Lansing, vi, 118-128, 1873. O'Reilly. J. Am. PracL, Louisville, ix. 327-334, 1874. Worms, J. Did. Encyclop. d. sc. med., Paris, xviii, 174-179, 1876. Jenks, E. W. Med. Rec, New York, xvii. 417-421, 1880. Goodell, W. Clin. News, Philadelphia, i, 219, 1880. .Aschenborn, O. Arch. f. k^in. Chir., Berlin, xxv, 174, 1880. Laub, H. Cynael. eg. obsl. Medd., Kjobenhagen, 3, R. iii, 29-37, 1881. Woodward, A. T. Med. & Surg. Reporter, Philadelphia, xlv, 398. 1881. Goodell. W. Phila. M. Times, xiv. 756-758, 1883-4. Madelung, O. Cenlralh. f. Chir., Leipzig, xii. 761-764, 1885. Ferouson. A. H. Canad. Pracl. Toronto, xi, 233-235, 1886. Morion, A. E. Med. Reg., Philadelphia, iv, 126, 1888. Hale, E. M. Homeop. ]. Obsl., New York, x, 9-26, 1888. Grafe, M. Ein Beitrag zur Astiologie and Therapie der Coccygodynie. Ztschr. f. Ceburlsh. u. Cynak; Stuttgart, xv. 344-353. 1888. Sutton, R. S. A new and reliable remedy for coccygodynia and puntis am. Med. & Surg. Reporter, Philadelphia, Ixiii. 563. 1888. Kuezora. W. Ueber Coccygodynie und ihre Behandlungsweise. Wiirzburg, 1888. Peyer. A. Centralb. f. Klin, med., Leipzie, ix, 657-662. 1888. Cooper. H. P. Atlanta M. & S. J., ns, vii. 1-10, 1890-91. Carriere. La sacro-coccygod. Echo. med. du nord. Lille, ii, 315, 1892. Cooper and Edv/ards. Diseases of the Rectum and Anus. 315, 1892. Phocas. G. Arch. prov. de chir., Paris, i. 407-412, 1892. Kasack. M. R. Ueber Coccygodynie. Berlin. 1892. Harris. A. H. North. Car. M. J., Wilmington, xxxi. 261-263, 1893. Barwell, R. Med. Week., Paris, ii. 149. 1894. Tilmann. Charite-Ann., Berlin, xix. 361. 1894. Montgomery, E. E. Charlotte N. C. M. J., vii, 711, 1895. Elliott. C. S. Med. Arena, Kansas City. iv. 257-262. 1895. Brenner. W. Med. Rec, New York. 1, 154. 1896. Rohleder. W. Ueber Coccygodynie. Berlin. 1896. Schaffer, O. (Pseudococcygodynie). Centralb. f. C\^nakol., Leipzig, xxi, 1249-1254. 1897. Fletcher. W. B. Indiana M. /.. Indianapolis, xvi, 301-304, 1897-98. Borst. Die angeb. Geschwulst. d. sacr. Region, Centralb. f. ailg. path. ii. path. anat.. Jena, ix, 449 501, 1899. Van Lennep, W. B. Hahneman Inst., Philadelphia, x. 136, 1902-3. Courtois-Suftt. Ann. d'hvg., Paris, 4. s, ii, 66-69, 1904. Ferrari, G. Policlin. Roma., xii, sez, prat. 1190-1193, 1905. Sutton. J. B. Clin. /.. London, xxxiii. 97-100. 1908-9. Courtois-Suffit & Bourgeous, F. Caz. d. hop., Paris, Ixxxiii. 1945-1949. 1910. SURGERY OF THE COCCYX. {Coccygectomy. Coccygogectomy. Tenotomy. The propriety of removing a part or all of the coccyx for anomalies, diseases and injuries can not be disputed, nor can any question arise for doing so when pain or tender- ness exists without these conditions. Pag-e Sixty-Five Historv. Coccygeciomy has been done for deformity, disease and injury without danger or inconvenience. Nott, 1 832, was first to report the removal of the coccyx. Thomas, 1835, removed it for parasitic infection, and Nott again, 1844, and Simpsofr, J. Y., 1861 , were among the first to call attention to pain, disease and deformities of the coccyx. Todd, 1874, cured neuralgia of the coccyx and pelvic viscera by coccygectomy. Blackwood, 1879, wrote on the necessity of accurate diagnosis of fractures at the sacro- coccygeal junction, drawn inward and the lemoval of the coccyx, and Stcuiford, 1879, and Burt, 1881, cases of pain cured by removing the coccyx. Garretson, 1 881 , applied the surgical engine for the purpose of removing the coccyx. Guillet, 1882, reported a case of dermoid cyst removed from the ano-coccygeal region and Cottrell, 1 883, reported having performed Garretson's operation (surgical engine) for the removal of the coccyx without disturbance of the perineum. Imlach, 1885, removed the coccyx for caries, and Welch, 1886, for neuralgia, Evans, 1887, cured mental symptoms by removing a necrosed coccyx. Bowlby, 1 889, reported three cases of coccygeal cysts, and Davis, 1 892, one of extirpation of the coccyx in which was located a congenital cyst. Kasley, 1 893, records a case of irreducible luxation of the coccyx which was cured by extirpation, and Coe, 1 895, one of dermoid cyst of the coccyx. Adler, 1895, cured by excision of the coccyx constant pain resulting from an un- united fracture, while Brewer, 1 896, states that the knife for coccygodynia is a failure, Liell, 1897, excised the coccyx in four cases of fracture and necrosis. Hirst, 1897, one for ununited fracture and Lange, 1897, one for dermoid cyst, de Vesian, 1907, injected alcohol (60 per cent.) about the coccyx for rebellious pain. Courlois-Suffit & Bourgeois, 1910, interpretated the medico-legal question of sur- gical intervention in pain due to injuries to the coccyx, thus showing that there are many medico-legal phases concerning this bony appendage. Berber in 1910 ablated successfully a hernia of the spinal cord in the region of the coccyx in an infant as was also done by Brad during the same year. Until within the last ten years coccygectomy was done more frequently for neuralgia than for all other causes combined, but this operation grows rapidly in favor for fractures, ankyloses and flailed conditions, especially when they excite great general irritability without pain, neuralgic in character. Technique. Coccygectomy — Complete — Incomplete. Complete. Removal of all the coccyx may be easily accomplished, with local or pul- monary anesthesia, preferably local, through a median incision extending from the first to the fifth segment, after separating the soft parts from the coccyx with a periosteome and dividing the bone with sharp forceps. The hemorrhage is usually insignificant, but drainage should always be instituted, because of the great possibility of infection of tissues so in- timately related to the anus and vulva. The same methods should be followed with partial excision of the coccyx, care always being observed in both instances not to injuie the rectal wall. Sutures when possible, should be avoided because of the distress caused by their presence. They should when necessary be inserted close to the edges of the incised skin, but many such incisions will close by the infold of the cut edges without suture. Gant, 1902, Diseases of the Rectum and Anus, second edition, pp. 168-1 72, tab- ulates 37 cases operated for injuries and tumors. Personal Coccygectomies (Acquired) . 3 Sarcoma, one 5|/2 lbs., one 7 oz., and one 2|^-^ lbs. 2 Necrosis ; one syphilis, one tuberculosis. 1 Fractures ; four males, six females. 1 1 Neuralgia; six females, five males. 6 Ankylosis; four males and two females. Two right angle (males), one right angle (female). Pag-e Sixty-Six Cocc\)gectom^ (Congenital). 1 long, sharp and flexible, (male). 2 long, sharp and flexible, (female), also 9 of recent date. Total, 44. TENOTOMY. Tenotomy, suggested by J. Y. Simpson, 1861, is done by dividing subcutaneously the soft structures along the lateral borders of the coccyx. This method has received high commendation by quite a number of operators but the results observed after three such operations upon as many subjects, by as many operators, are not commendable. Technique for tenotomy may best be accomplished by a posterior lateral incision ex- tending through the cutaneous and other soft tissues overlying the coccyx, the incision being upon one or both sides, as necessity may require. With the left index finger within the rectum and upon the coccyx for a guide, the danger of incising the wall of the rectum may be avoided, as the tendons are divided at their attachments along the lateral bony borders. The point of a narrow bladed knife may be made to pass from the tip of the coccyx upward, or from its sacral border downward, there being no special advantage with either course, but the incision should extend about one and one half inches downward from the tip of the coccyx. There may be difficulty in palpating the entire rectal surface of the coccyx, but this IS only when it is very short or when the subject is extremely fleshy, or of great height. This difficulty is more frequently encountered in the male subject, because these con- ditions may be overcome by an examination of the female coccyx, with the finger in the vagina. The after care of such posterior incisions is the same as for coccygectomy already de- scribed. Trans rectal tenotomy is a method not to be recommended because the incisions are made through the rectal wall along the lateral borders of the coccyx, wath a knife upnan a long handle inserted through a speculum, thus being more difficult and dangerous because of the possibility of infection and hemorrhage, sufficient causes for condemnation. Novocain or cocain injected subcutaneously will suffice for anesthetic purposes, the pulmonary method being seldom indicated for either excision of the coccyx or incision of its tendon. BIBLIOGRAPHY. (Surgical.) Excision : Thomas. Prov. San. Ber. d. Med. Coll. v. Pommern, i&34, Stettin. 79-81, 1835. Nott, J. C. Nerv Orleans M. /., i, 58, 1834-1844. Simpson, J. Y. Med. Times & Caz., London, i, 317, 1861. Kidd, G. H. Med. Press & Circ, Dublin, 1867, 111, 596-598, also Dublin Q. /. M. Sc, xliv, 477-481, 1867. Bourillion. Neciose du coccyx paralysie generale procedee d'un affection de la moelle symptoms de paralysis agitans autopsie. Rec. d. trav. Soc. med. d'obs., Paris, 1866-70, 2, s, li, 455-464. .Also in Caz. d. hop., Paris, xliii, 198, 202. 1870. Amann, Aertzll. Int. hi., Munchen, xvii, 394, 1870. Adams, Z. B. Rec. Bost. Soc. M. Improve., 1866-74, vi, 140; also Boston M. & S. /.. v, 458, 1870. Plum. Hasp. Tid., Kjobenhagen, xiii, 33-35, 1870. Simpson. J. Y. In his Works (Dis. of Women) Edinburgh, iii, 202-224, 1871. Betz, F. Memorabilien, Heilbronn, xvi, 40, 1871. Seelismuller, .\. Coccygodynie seit zwolf Jahren bestehend, geheilt durch den faradischen Strom. In his Neuropathol. Beobacht., Halle, 25-27, 1873. Todd, S. S. Med. Herald, Leavenworth, 1874-5, viii, 99; also Kansas Ciip M. J., iv, 138. 1874. Svenson, I. Upsala Lakaref, Fori}., xi, 337-339, 1875-6. Irish. J. C. Boslon M. & S. J., xcii. 613, 1875. Mursick. G. A. Am. J. M. Sc, Philadelphia, clxi, 122-124, 1876. Broca. Sur un cas de traumatisme frave du coccyx ayant necessite la resection. Tribune med Paris, xii, 112-114, 1879. Pag:e Sixty-Seven Blackwood, W. R. D. Ptoc. Phila. Co. M. Soc, Philadelphia, 1880, ii, 56, also PhUa. M. Times, X, 295, 1879-80. Stanford, F. A. A'en> York M. J., xxx, 400, 1879. Burt, W. J. Mississippi Valley M. Month., Memphis, 1, 1-4, 1881. Garretson. Phila. M. Times, xii, 303, 1881-2. ^ Guillet. /. de Med. de I'Ouest, Nantes, xvi, 240, 1882. Binzer. Gl;nae^. og obsL Medd. Kjobenhagen, iv, 1, 2, Hft. 52-61, 1882. Browne, B. B. Maryland M. J., Baltimore, ix, 284, 1882. Marr, L. Hosp. Tid., Kjobenhagen, 2, R, ix, 284, 1882. Ward. yVen> Yor^M. /., xxxvi, 70, 1882. Werner, Marie. B. Med. & Surg. Reporter, Philadelphia, xlviii, 287, 1883. Cottrell, 3. P. Independ. PracL, New York, iv, 8-10, 1883. Dawson, B. F. Am. ]. Obst., New York, xvi, II 89, 1883. Harrison, G. T. New York M. J., xxxvii, 268, 1883. Macdonald, A. Tr. Edinb. Ohsl. Soc, x, 183, 1884-5. Goodell, W. Med. & Surg. Reporter, Philadelphia, 1, 588, 1884. Browne, B. B. Maryland M. J., Baltimore, xiii, 26, 1885. Tilaux. Practicien, Paris, viii, 293-295, 1885. Imlach. Brit. Gpnec. /., London, i, 319, 1885. Welch, C. T. Tr. M. Soc., New Jersey, Newark, 288. 1886. Whitehead, W. Lancet, London, i, 112, 1886. Odell, W. Lancet, London, i, 1088, 1887. Evans, Z. H. Phila. M. Times, xviii, 351, 1887-8. von Swiecicki. Wien. med. Presse, xxLx, 1136, 1888. Bowlby, A. A. Tr. Path. Soc, London, xli, 284-289, 1889-90. Post, A. Boston M. & S. /., cxxiii, 300, 1890. Sutton, B. Med. Presse & Circ, London, ns, liv., 607, 1892. Lucy. Lancet, London, ii, 1046, 1892. Davis, E. P. Am. Gijnec. & Pediat., Philadelphia, vi, 542, 1892-3. Pine, Aleinda A. Northwest Lancet, St. Paul, xii, 180-182, 1892. Early. T. B. Med. Ball., Philadelphia, xv, 138, 1893. Coe, H. W. Pacific M. Rec, Portland, Ore., i, 78 1893. Adler, L. H.^ Jr. Med. News, Philadelphia, Ixvii, 348, 1895. Jackson, J. N. Langsdale's Lancet, Kansas City, i, 299, 1896. Bremer, L. Med. Rec, New York, 1, 154, 1896. Liell, E. N. Med. News, New York, Ixx, 382, 1897. Hirst, B. G. Am. J. Obst., New York, xxxv, 794, 1897. Lange, K. Eira, Stockholm, xxi, 352, 1897. De Vesian. Rev. Prat, de g\^nec. d'obst. el de pediat., Paris. Ixxxii, 206-263, 1907. Irwin, J. R. Charlotte (N. C.) M. J., Iviii, 170, 1908. Pons. Kyste dermoide de la region coccygienne. Marseille med., xlvl, 167-169, 1909. Cortois-Suffit & Bourgois, F. Soc. de med. leg. de France Bull., Paris, xhi, 239-255, 1910. MISCELLANEOUS BIBLIOGRAPHY. (Coccyx.) Miscellaneous Bibliography. Krimer, W. Bruch des Steissbein's, Ursache langjahrner Nervenleiden. Med. ConVers. Bl., Hud- burgh, 1, 93-96, 1830. Godfrey, A. Am. J. M. Sc, Philadelphia, ns, xhi, 576, 1860. Broers, H. J. Bijeen Jong meisie. Nederl. Tifdschr., v, Heelen Verlosk, Utrecht, xiii, 595-601, 1862-3. Horschelmann. St. Petersb. med. Ztschr., iii, 117-120, 1862. Betz, F. Ueber den wahrend der Geburt entstehenden Steissbeinbruch. Memorabilien, Heilbronn, X, 58-62, 1865. Arnold, J. Zur Steissdriisenfrage. Arch. f. path, anal., Berlin, xxxiii, 454-456, 1865. Arnold, J. Ein weiterer Beitrag zu der Steissdriisenfrage. Arch. f. anal., Berlin, xxxv, 220-223, 1866. Fox, W. R. Chicago M. Exam., xl, 76, 1870. Gilette. Courrier med.. Pans, xxiv, 235, 1874. Lanz, E. Ueber die Beweglichkeit des Steissbeines und ihre Beziehung zu der Geburt. Bern, 1878. Greve. Ein Fall von Schwanzbildung beim Menschen. Arc. f. path, anal., Berlin, Ixxii, 129, 1878. Ornstein. Schwanzbildung beim Menschen. Verhandl. d. Berl. Cesellsch. f. AnthropoL, Berlin. 303-305, 1 pi, 1879. Post. Disease of coccyx. A^eD; York M. J., xxx, 517, 1897. Bartels, M. Eine schwanzahnliche Neubildung beim Menschen. Arch. f. path, anal., Berlin Ixxxiii 189-192, 1 pi., 1881. Virchow, R. Schwanzbildung beim Menschen. Arch. f. path, anal., Berlin, Ltxxiii, 560, I pi., 1881. Schmidt, M. Zwei Falle von Geschwiilsten in der Gegend des Schwanzbeines. Arb. a. d chir Univ. Poliklin., zu Leipzig, 2 Hfte., 15-22, 1892. Blum, F. Die Schwanzmuskulatur des Menschen (Freiburg i. B.) Wiesbaden, 1894. Page Sixty-Eight CHAPTER IX. URETHRA. ANATOMY. ITH THE exception in length of the urethra, the urinary apparatus in the male and female are similar, especially alike from the lower portion of the bladder to and including the kidneys. The urethra m the male is of two portions, approximately less than 2-3 cm. long from the bladder to the opening of the ducts of reproduction, the membranous portion 1 cm. and the distal or spongy portion terminating with the external meatus, I 4 cm. long and is lined with a mucous membrane throughout. It contains much fibrous tissue with the muscular coat of circular and longitudinal fibers, intermingled with many lymphatic glajids. Stripped muscle fibers are present in the outer aspect of the muscular coat of the urethra, forming a complete ring or sphincter in the upper part, while the lower fibers form the uro- genital sphincter. An imperforate urethra, when complete in the unborn, is said by Deaver to always cause death before delivery, but two personal experiences do not bear out this statement. Urethral blood supply is from the spermatic or ovarian internal iliac, visceral vessels, inferior renal arteries, inferior vesical and middle hemorrhoidal arteries. Urethral nen>es are from the pudlc which carry sensory fibers to the mucous membrane and motor fibers to the striped muscle, and from the hypogastic and renal plexus of the sympathetic by way of the prostatic, cavernosus plexuses and pelvic sympathetic plexuses. The compressor urethra is also dominated by branches of the pudlc nerve. Its function is to constrict the membranous urethra in the male and flatten the walls of the vagina in the female. The lymphatics of urethra in the male (Sappy) arise from a network attached to the mucous membrane from the utricle to the meatus urinarlus. Posteriorly, the network formed by these vessels and by the anastomosis which unites them, is con- tinued on the vesiculae semlnales and the vasa deferentla. In front it is continuous with the tortuous branchlets on the surface of the gland. This network has an exceptional arrangement; the larger and smaller branches which form It, follow the direction of the urethral walls by many transverse and oblique anastomoses; they unite very frequently and are grouped in parallel and unequal bundles, separated by longitudinal ridges. From this network emanate several collecting trunks which may be divided into four groups. The onl\) collecting trunks which Sappy mentions, are those which come from the mucous membrane covering the glands. They transverse the Inferior wall of the urethra at the level of the fraenum, unite with the lymphatic trunks coming from the glans, ^^ of folds of mucous membrane when the ureters do not enter di- rectly into it, or directly when they enter the bladder. It is largest at its base and varies in size and shape, very distensible, located in the extreme lower pelvis and richly endowed with blood, lymphatic vessels, glands and nerve fibers. It varies in thickness because of being distended and is composed of mucosa within, a serosa without, and muscular fibers between the two layers. Its blood, lymphatic and nerve supplies are alike in the male and female. The blood suppl); is from the superior middle and inferior vesicle, obturator and internal pudic arteries and branches of the uterine and vaginal arteries in the female. The venous plexus about the organ is larger at its base and communicates with the prostatic plexus from the vesico-prostatic plexus which empties into the internal iliac vein. Its fundus or base, spermatic ducts, and recto-vesical pouch are directed toward the rectum, and in the female, is attached to the anterior vaginal wall. The arteries are chiefly the inferior and superior vesical from the anterior division of the internal iliac, reinforced by branches from the middle hemorrhoidal and twigs from the internal pudic and obturators. Nerves include sympathetic and spina] fibers; the sympathetic follow the arteries and join the vesical branches from the sacral plexus which is derived from the 3rd and 4th and possibly the 2nd sacral spinal nerves. The larger nerves divide in the outer fibrous coat of the bladder, into small fibers that are connected with ganglia especially near the ureters. The bladder in general is but a trifle sensitive, but it is very sensitive about the entrance of the ureters into the bladder at which point nerve fibers predominate. Fibers from the pelvic plexuses of the sympathetic and third and fourth sacral nerves supply the urinary bladder, while fibers from the sympathetic plexuses supply the ureters and fibers from the hypogastric plexuses of the sympathetic with central fibers mingled with Pacinian corpuscles, inhibit the prostate gland. Tlie lymphatics of the bladder. The only network of origin which exists in the bladder is an intramuscular one. The emergent vessels of this network end in a second network placed on the outer surface of the vesical muscle, under the peritoneum of the umbilico-praevesical fascia. The course and termination of the collectors of this net- work vary according to their situation on the anterior or posterior surface of the bladder. Anterior surface. The collecting trunks coming from the anterior surface form two groups. The trunks coming from the inferior segment of this surface run almost transversely outward, and pass into a gland placed on the lateral surface of the pelvic cavity, between the external iliac vein and the obturator nerve, a few millimeters behind the cervical ring. The trunks which come from the superior part of the anterior surface are remarkable for their sinuosities. They run upwards and outwards, cross the hypo- Page Seventy-Three gastric artery, passing either above, or not frequently below it, and eventually terminate in the middle gland of the middle chain of the external iliac group. In the course of these lymphatic trunks are placed small glands, which are only visible after injection, they belong to the group of interrupting glomular nodules. Some of these glaftds are placed in front of the bladder (pre-vesical glands) , they maj' become hypertrophied in cer- tain pathological conditions (Bazy) and may form the starting point of certain prae-vesical phlegmons. Others are placed at the spot where the lymphatic vessels cross the hypo- gastric artery, (latero-vesical glands. Waldeyer, Gerota). Posterior surface. The trunks which come from the posterior surface, also form several groups. The trunks which come from the superior portion of this surface run outwards describing several curves. They cross the hypogastric artery, where they traverse some small lateral-vesical glands, and terminate in the external iliac gland in which the superior lymphatics of the anterior surface also end. Other trunks pass backwards following the course of hypogastric artery, and end in a gland which is situated like the preceding, on the external iliac vein, but more posteriorly to it, immediately in front of the bifurcation of the common iliac artery. Other trunks which come from the middle segment of the posterior surface, end in the hypogastric glands. Others finally arising from near the neck of the bladder run directly backwards, and crossing the lateral surface of the rectum, ascend onto the anterior surface of the sacrum and terminate in the glands situated in the angle of bifurcation of the abdominal aorta, in front of the promontory. The vesical lymphatics end in the glands of the bifurcation of the aorta. We may add that the prae-vesical network is continuous with the network which surrounds the prostate, the vesiculae seminales, the vasa deferentia, and the terminal parts of the ureters. Etiology. Anomalies, Diseases and Injuries. Anomalies. Injuries. ANOMALIES. Anomalies may be congenital or acquired, primary or secondary, inverted, ex- ceedingly large or small, entirely absent, open upon the abdominal wall, (exstrophy), abnormally placed in the pelvis, partially or completely septinated, or contain two or more cavities, when the urachus is present. Ectopy is evidenced by the bladder protruding through a cleft in the abdominal wall. DISEASES. Benign. Malignant. BENIGN. Cystitis may be primary or secondary, acute or chronic, local or general, mild or severe. Atrophy may be congenital or acquired, primary or secondary, local or general. Usually in all of the structures. Pag-e Seventy-Four H^perlroplt^ may be congenital or acquired, local or general in any one or all of the structures, usually all, primary or secondary. Ulcers may be congenital or acquired, primary or secondary, single or multiple, vary in depth, due to trauma or infection, acute or chronic, in any tissue or portion of the bladder wall, cease or continue in size or disappear spontaneously. Fissures at the neck may be congenital or acquired, usually acquired, acute or chronic, single or multiple, primary or secondary, usually in the mucosa, sometimes the muscularis. Papillomata are probably the most frequent forms of new growth in the bladder. They may be congenital or acquired, single or multiple, upon any portion of its inner surface, develop to considerable size, remain quiescent or disappear spontaneously, though such a resolution seldom occurs. Ader\orr\ala frequently found in the bladder, may be congenital or acquired, single or multiple, (usually multiple), upon any portion, small or large, cease to develop but seldom disappear spontaneously. Polypi may be congenital or acquired, single or multiple, large or small, pedun- culated, vary in shape and location. Fibromata may be congenital or acquired, single or multiple, usually single, in any portion of the muscularis, where they originate, remain small, become large, cease to grow, or disappear spontaneously. Myomaia may be congenital or acquired, primary or secondary, vary in size, shape, number and location. Angiomala may be congenital or acquired, primary or secondary, acute or chronic, vary in size, number and location and disappear spontaneously. Liponiata may be congenital or acquired, primary or secondary, vary in size, shape, location and number. Chondromala may be congenital or acquired, primary or secondary, vary in size, shape, location and number. Tuberculosis may be primary or secondary, single or multiple, acute or chronic, involve any part or all of the bladder, or disappear spontaneously. Syphilis may be congenital or acquired, primary or secondary, single or multiple, in any portion or all of the bladder. Parasites may be congenital or acquired, primary or secondary, without or within, become encysted, or remain in the bladder cavity, the most common being cysticircus. Any form may be temporary or become permanent. Concretions may be congenital or acquired, primary or secondary, single or multiple, vary in size, location, encysted in any portion of the wall of the bladder, especially in its lower extremity, originate in the kidney or ureter, and pass into the bladder. Foreign Bodies may be introduced by accident or design, be single or multiple, enter from ^vithout or within, through the urethra, surrounding soft structures, ureters, uterus or peritoneal cavity and escape from the bladder into any one or more of these cavities or tissues. Cysts may be congenital or acquired, single or multiple, large or small, in any portion of the bladder wall, contain pus, blood, serum, urme or parasites, such as ecchinococci, or other forms, rupture into the rectum, vagina, uterus, peritoneal cavity, bladder, urethra, or soft structures externally. Fislulae may be congenital or acquired, single or multiple, primary or secondary, acute or chronic, vary in size and length, through any portion of the bladder wall, open externally through the soft structures into the rectum, vagina, uterus, peritoneal cavity, urethra or seminal vesicles. MALIGNANT. Carcinomata may be primary or secondary, usually primary and single, in 2uiy portion of the bladder wall and of slow or rapid growth. Page Seventy-Five Sarcomata may be primary or secondary, usually primary and single, upon any portion of the bladder wall and slow in their development. INJURIES. Herniae of the bladder, usually in the groin, may be congenital or acquired, into the rectum, vagina, through the inguinal canal or abdominal wall, of rare occurrence, but sufficiently frequent to require consideration. The inguinal variety is almost always unilateral, the perineal usually due to pregnancy, the urethral is the inversion of the bladder, occurs only in the female, the crural form exceedingly rare. Ruptures may be by accident or design, primary or secondary, complete or incom- plete, single or multiple, due to force applied from without or within, in any portion of the bladder wall, extend into the peritoneal, uterine, rectal or vaginal cavities, complicate ureters. Fallopian tubes, bloodvessels, nerves, lymphatics, intestines, cutaneous structures or abdominal wall. Incisions may be by accident or design, single or multiple, penetrating or non- penetrating, from without or within, to the same degree as rupture. Punctures may be by accident or design, single or multiple, penetrating or non- penetrating, without or within, through any of the overlying structures, involve any of the associated organs, through the rectum, vagina, urethra, or peritoneal cavity. SYMPTOMS. Symptoms pertaining to the urinar^) bladder are quite varied and uncertain, especially because of the great variety of conditions found within its structures, and the adjacent soft tissues, and because of their inhibition being from the same source, and similar in both sexes. Any one of the conditions herein ascribed, involving the bladder, may cause subjective symptoms identical in character. It is inhibited by both motor and sensory fibers from the pelvic plexus of the sympathetic, and third and fourth sacral nerves, and therefore must be a source of great general disturbance within the uro-genital and rectal tracts, especially as their fibers coalesce with the motor and sensory fibers of other nerves. The bloodvessels and lymphatics alike coalesce with their associates, adding greatly to this general disturbance. Local manifestations in the bladder such as tenderness and pain may or may not vary with the degree of involvement as may those that are general, which are indicated by increased sensibility, pain, chill, headache, shock, with added nausea and vomiting. The effect of neuroses of any character upon the urinary system and its associated structures or organs, is shown by the frequent desire to void urine. Incontinence or reten- tion may also occur as may tenesmus or the sensation of burning be induced by nervous irritability. Page Seventy-Six CHAPTER XI. URETER. ANATOMY. >^ ^-^ ^^ jr> HE URETER is composed of mucous, muscular and fibrous coats ^ I^ Sf w rather thick and white. C/^/^ >^\^^ ^/ic mucous membrane has many layers of epithelial cells, and the muscular coat is composed of unstriated muscle fibers in bundles which are separated by connective tissue and arranged longitudmally and cnxularly. The fibrous coal varies in thickness at different levels, the lower part blending with the connective tissue which lies among the muscle fibers forming the sheath of the ureter. In the female about three inches can be palpated through the vagina. The ureters extend from the bladder backwards, outward and upward to the base of the broad ligaments and toward the lateral walls of the true pelvis. The ureters are behind the peritoneum covering the psoas muscle and in front of the common iliac arteries, and in the true pelvis in front of the in- ternal iliac arteries, entering the bladder about one inch apart. Blood supp/l; is from the renal and spermatic arteries in its abdominal portion and the superior vesical and the middle hemorrhoidal vessels in its pelvic portion. Nerve supply is through the renal, the spermatic and hypogastric plexuses. Lymphatics of the Ureter. Our knowledge of the lymphatics is still imperfect. Sappy was able to inject them only in the horse, and met with them only in the muscular coat. In the course of his injections of the vesical lymphatics several times he has seen the subserous network of the bladder extend itself a few millimeters round the ureter. The lymphatics of the ureter end in multiple collecting trunks which pass to the neighboring glands. ETIOLOGY. Anomalies, Diseases and Injuries. Anomalies. ,g f Benign. 1^ Malignant. Injuries. Di ANOMALIES. Anomalies may be congenital or acquired, primary or secondary, single or multiple, vary in length, size, origin, entrance into the bladder, course and relation to other structures, one or both absent, the right enter the bladder upon the left, the left upon the right side, or anywhere upon the surface. Page Seventy-Seven DISEASES. Benign. Malignant. BENIGN. Urethritis may be primary or secondary, acute or chronic, and involve any part or all of the mucosa. Tuberculosis may be acute or chronic, primary or secondary, in any portion, in the mucosa or any of the fibers w^ithin the wall. Primary tuberculosis, however, is much less frequent than the secondary form, which is usually from the kidney or bladder, especially the kidney. Syphilis may be congenital or acquired, primary or secondary, single or multiple, acute or chronic, in any portion of the ureter, but more frequently near the extremities, in which instance it is usually secondary. Papillomata may be congenital or acquired, usually acquired, primary or secondary, single or multiple, in emy portion, but most frequently at the extremities, destroy the lumen, cause the formation of concretions, strictures or general destruction. Adenomata may be congenital or acquired, single or multiple, not pedunculated, in any portion, but most frequently at the extremities, destroy the lumen, cause concretions, strictures or general destruction. Fibromata may be congenital or acquired, single or multiple, large or small, originate in the muscular tissue of the ureter, destroy the lumen, and cease to grow at any stage of development. Prolapsus may be congenital or acquired, acute or chronic, into the bladder, vagina, through the inguinal or femoral ring. Concretions may form within or enter through the kidney and foreign bodies through the peritoneal cavity, or from without through the overlying structures, single or multiple, primary or secondary, remain or pass into the kidney, bladder, peritoneal, rectal, vaginal, uterine cavity, or exterior through the overlying soft structures. C})sts may be congenital or acquired, single or multiple, primary or secondary, parasitic or non-parasitic, within the lumen, muscular coat of the ureter, rupture into the ureter, kidney, bladder, vaginal, uterine, rectal, peritoneal or intestinal cavities, through the cutaneous structures. Fallopian tubes or blood vessels. Strictures may be congenital or acquired, single or multiple, primary or secondary, partial or complete, vary in size, shape, and in any portion. Fistulae may be congenital or acquired, single or multiple, primary or secondary, acute or chronic, in any portion of the ureter, open into the rectum, vagina, uterus. Fallopian tubes, peritoneal or alimentary cavities, or through the overlying soft cutaneous tissues. MALIGNANT. Carcinomata may be primary or secondary, single or multiple, in any portion or structure. Sarcomata may be primary or secondary, single or multiple, in any portion, especially the muscularis, slow or rapid in growth, depending upon their character and origin, the result of accidental or induced injury, the presence of concretions, foreign bodies, or the introduction of sounds, and of myxomatous, rhabdomyomatous, or other varieties. Page Seventy-Eight INJURIES. Ruptures of the ureter may be primary or secondary, single or multiple, partial or complete, longitudinal or circular, lateral, posterior or anterior, into the peritoneal, uterine, rectal or vaginal cavities, bladder, surrounding soft structures, or kidney. Punctures may be induced from within, primary or secondary, through the kidney or bladder, result from foreign bodies, concretions or introduction of sounds, through the peritoneal, uterine, rectal, or vaginal cavities, or overlying soft structures, and in any portion of the ureteral vv^all. Incisions may be accidental or induced, primary or secondary, longitudinal, or circular, in any portion of the ureteral wall, kidney, bladder, through the rectal, vaginal, uterine, or peritoneal cavities, or through the overlying soft structures when induced for extra-peritoneal ureterotomy. SYMPTOMS. Symptoms pertaining to ureteral conditions herein described too frequently fail in diagnosis, especially the symptoms of pain and tenderness, two of the prominent and constant mdications, because the sensitive nerve fibers which supply the ureter are intimately associated with those of the kidney and bladder and their adjacent structures, thus permitting similar impulses due to nregular conditions within them to be transmitted through their nerve fibers. This difficulty obtains with the existence of occlusion which greatly aggravates all others and becomes the most prominent factor. Pain and tenderness in the ureter predominate in local manifestations but un- fortunately they are not diagnostic, especially in the female, but when they persist with general disturbances such as chill, headache, shock, perspiration, nausea and vomiting, sufficient evidence is deduced to suspect ureteral conditions. There is probably no part of the genito-urinary tract so difficult to determine symptomatically. Tenderness may indicate many conditions or none at all because its degree varies with the closeness of the ureteral lesion to the bladder which increases intensity. Bladder symptoms of every kind, especially those due to irritation, frequent urination and tenesmus are very confounding. The lower male ureter may sometimes be palpated through the rectum, but the point of lesion is not then made certain. Page .Sevoiit\-Nim CHAPTER XII. KIDNEYS. (Male and Female.) ANATOMY. Fig. 46. IDNEYS exceed in weight that of the other urinary tissues com- bined, bmt their consideration will be but slightly more than passing because their blood, nerve and lymphatic systems are independent of the other portion of the urinary apparatus and far distant from the pelvic tissues. It might be said that there is no physiologic relation of the kidneys to the other portion of the urinary tract, except that of a mechanical character, because of their independent relation. Blood Vessels. There should be one renal artery for each kidney, but there may be two or even more and the right is greater in length. Vessels supplying the kidney do not anastomose with each other as each end artery provides for a particular area of renal substance (Piersol). The nerves of the kidney are derived from the renal plexus Page Eighty formed by contributions from the solar and aortic j^lexuses and the least splanchnic nerve. The plexus accompanies the renal artery which it surrounds. Within the latter is formed a well-marked perivascular network from which a number of twigs are given off to supply the walls of the pelvis and ureter, while the majority accompany the vessels into the kidney. Because of the almost total absence of sensory nerve fibers in the kidney tissue, very little if any pain, can be produced within from any cause except obstruction. I he lymphatics of the l(idney)s arise from two networks, one superficial and the other deep. The superficial network, which was observed by Mascagni, has not been seen by Ludwig and Kolliker. The new classical researches of Leichmann and Stahr, however, leave no doubt as to its existence; but it is extremely difficult to infect. Immediately under- neath the capsule, it is remarkable for the tenuity of its meshes. This network tw^o systems of collecting trunks arise which, following Sappy, we may divide into convergent and divergent. The convergent empty themselves into the collecting trunks of the deep network either by immediately sinking into the depth of the kidney, or by running under the capsule only to join the deep collecting trunks near the hilum, the divergent trunks perforate the fibrous capsule, and pass into the network which vv^e shall describe further on when dealing with the fatty capsule of the kidney. The ar- rangement of the deep network eventually gives origin to large collecting trunks, varying in number from four to seven, which leave the kidney at the hilum. These trunks course around the artery and the renal vein. They are usually satellites of the vein, some running on into anterior, and some on its posterior surface. The mode of termination of the renal lymphatics varies on the two sides. On the right, we may divide the vessels into anterior and posterior. The anterior trunks run in front of the renal vein, and pass downwards and inwards and terminate in the pre-venous mass of right juxta-aortic glands. They usually terminate in the group of the above mentioned glands, which is situated on the anterior surface of the vena cava, immediately below the opening of the renal veins into the inferior cava, but one of them may often be seen to end in a gland belonging to the same group, placed much lower down, close to the bifurcation of the aorta. It is equally common to see one of these trunks end in a gland of the pre-aortic group. The posterior trunks are shorter than the preceding, and are placed behind the vein and renal arteries. They terminate in two or three large glands situated behind the inferior vena cava, in front of the right pillar of the diaphragm. These glands belong to the retro-venous group of the right juxta-aortic glands. Their different vessels pass through the right pillar of the diaphragm traversing it through the same orifice as the great splanchnic nerve, and ter- minate in the thoracic duct. On the left, the collecting trunks, which leave the kidneys at the hilum terminate in four or five glands which belong to the juxta-aortic group of the corresponding aorta. The highest of these glands are situated in front of the left pillar of the diaphragm, through which their efferent vessels pass on their way to join the thoracic duct. To sum up, the lymphatics of the kidneys end principally in the juxta-aortic glands of the corresponding side and accessorily in the pre-aortic glands. In any case it is, if not absolutely incorrect, at least insufficient, to state that the lymphatics of the kidneys terminate in the glands placed at the level of the hilum of these organs. At the level of the hilum, however, we may meet with some small glandular nodules, but by reason of their contiguity and their small size, they should be regarded as belonging to that variety of gland which we have described above as the interrupting glandular nodule (Schalt- driisen) and which it is important to distinguish from the regional glands which are much more constant in their presence and situation (Stahr). One of these nodules is, however, distinguished by its relative frequency and by its fairly constant situation beneath the right renal vein, in the angle which this vessel forms with the inferior vena cava. The fatt^ capsule of the l(idne^ possesses a rich lymphatic network which has been recently described by Stahr. The efferents of this network end in the same glands as the collective from the kidney itself. The network of the fatty capsules communicates, as Page Eighty-One we have seen, with the lymphatics of the kidney, and it is not rare to find during the progress of epithehal cancers of this organ, lines of new growth in the fatty capsule. Lymphatics of the Suprarenal Capsule. — The lymphatics of the suprarenal capsules, whose mode of origin will be studied together with the structures of these organs, end in four or five collecting trunks, which emerge at the same point as the large centre^^ vein, and terminate in the juxta-aortic glands of the corresponding side. In several subjects, these collecting trunks have been seen to perforate the pillars of the diaphragm and end in the glands placed between the posterior surface of these pillars and the vertebral column. ETIOLOGY. Anomalies, Diseases and Injuries. Anomalies. Diseases | Bf^/.^"- (^ Malignant. Injuries. ANOMALIES. Anomalies may be congenital or acquired, vary in shape, size, position, number and relation to other structures. One or both may be absent, which last event would preclude the possibility of life existing after birth for any great length of time, but the absence of one does not prevent the continuance of life. One or both kidneys may be ex- cessively lobulated, large or small, and functionate normally in amount and frequency. One or more ureters originate in the same kidney and the proverbial horseshoe kidney, probably exists as one kidney. DISEASES. Benign. Malignant. BENIGN. Nephritis may be congenital or acquired, primary or secondary, unilateral or bilateral, acute or chronic, local or general, mild or severe. Tuberculosis may be primary or secondary, acute or chronic, single or multiple, more frequently primary, infected simultaneously, at different times, or one alone affected, ap- pear in any portion, disappear spontaneously, or continue to its destruction. Syphilis may be congenital or acquired, primary or secondary, single or multiple, in any portion of one or both simultaneously. Papillomata may be congenital or acquired, primary or secondary, involve any por- tion or all of one or both, usually both. Adenomata may be congenital or acquired, primary or secondary, unilateral or bilateral, single or multiple, vary in size, shape, number and location. Lipomata may be congenital or acquired, primary or secondary, vary in size, shape, number and location. Rhahdomyomata may be congenital or acquired, primary or secondary, vary in size, shape and location. Concretions may be congenital or acquired, primary or secondary, single or multiple, remain in the pelvis, escape into the cortex, and vary in size (from sand-like grains, to several ounces) , shape and number. Fistulce may be congenital or acquired, single or multiple, primary or secondary, acute or chronic, originate in the pelvis, or cortex, appear in the peritoneal cavity, upon the Pag-e Eighty-Two cutaneous surface, through the overlying soft structures, pleural cavity, stomach, intestinal tract, rectum, vagma, bladder or Fallopian tubes. Floating l(idne^ may be congenital or acquired, primary or secondary, unilateral or bilateral, vary in degree; it is usually the right kidney and is more frequent in the female. Cysts may be congenital or acquired, primary or secondary, single or multiple, vary in size, shape, in any portion, the pelvis alone, contain blood, pus, serum, occeisionally ecchinoccocci, or dermoid material, rupture into the ureter, peritoneal, alimentary or pleural cavities. Fallopian tube, uterus, bladder, rectum, vagina or overlying soft structures. MALIGNANT. Carcinomata may be primary or secondary, usually primary, and single, and extend into the ureter before involving the surrounding structures. Sarcomata may be primary or secondary, usually primary, seldom multiple, and extend into the adjacent soft structures. INJURIES. Rupture may be accidental or induced, single or multiple, primary or secondary, from causes without or within, longitudinal or circular, each varying in extent, partial or com- plete, into the pleural or peritoneal cavity or overlying soft structures. Lacerations may be accidental or induced, primary or secondary, single or multiple, complete or incomplete, from without or within, in any direction, involve the peritoneal, pleural, or alimentary cavity or organs. Punctures may be accidental or induced, primary or secondary, single or multiple, in any part of the organ, from without or within, through the peritoneal cavity or the overlying soft structures, the result of instrumentation, through the ureter or pelvis of the organ. Incisions may be accidental or induced, single or multiple, primary or secondary, penetrating or non-penetrating, from without or within, in any portion of the organ, longi- tudinal or circular and involve the surrounding tissues. SYMPTOMS. Symptoms of f(idney irregularities are highly intensified because of its size, function and intimate association with organs of equal importance, namely the liver, pancreas, stomach, duodenum, biliary tract, and diaphragm, each of which is supplied with numer- ous sensitive nerve fibers, many of which are from the same origin, but few of which have even slight association with the perineal group. It is thus observed that nephritic symptoms are almost independent of those found in the uro-genital tract which is so thoroughly dominated by the sympathetic and sacral plexuses. For this reason nephritic symptomatology cannot be placed in parallel lines with that of the pelvic organs and perineum. But as all kidney secretions, both normal and abnormal, naturally drain through the ureters into the bladder to make their exit through the urethra, primary symptoms are produced within these organs and tissues which cause symptoms of all combined. The general influence of renal pathology is usually severe, and local manifestations, such as pain, and tenderness, are fair indications of beginning renal disease, but when these exceptions are increased in severity, and associated with chill, headache, shock, per- spiration, nausea, and vomiting, their intensity is lost. rage Eishty-Three CHAPTER XIII. ERECTILE BODY. (Penis Clitoris.) ANATOMY. Fig. 47. — Male urethra cleft dorsally (Deaver). "^OV Q/^ HE ISCHIO-CAVERNOSUM, also named erector penis, and w ji\ if Cy erector clitoris, represents the lateral portion of the sphincter S^/^ RxV-y^ cloacae. The two muscles occupy the lateral parts of the super- ficial perineal interspace, each arising from the base of the tu- berosity of the ischium enclosing the base of the crus penis- clitoris as in a sheath and passing forward to be inserted into the corpus cavernosum. The muscle in the female differs from that in the male only in size. Its function is to compress the corpus cavernosum and thus assist in producing or maintaining erection of the penis or clitoris. The artery of the corpus cavernosum (profunda penis in the male, profunda clitoris in the female) is usually the larger of the two terminal branches. Immediately after its origin it enters the crus penis and runs forward in che corpus cavernosum which it supplies. Bulbo Cavernosum differs in its relations in the two sexes, being in the male the ac- Page Eig'hty-Four celerator urinae, the two muscles of the opposite sides being united in a median fibrous raphe which extends forward from the central tendon of the perineum over the bulbo and corpus spongiosum. Arising from this raphe the fibers are directed laterally and forward over the bulb and corpus spongiosum to become inserted into the under surface of the inferior layer of the uro-genital trigone and into the fibrous sheath of the corpus caver- nosum, some of the more anterior fibers being continued dorsally to be inserted mto the fascia covering the dorsum of the penis and forming what has been termed the muscle of Hauston, or compressor venae dorsalis penis, and sphincter vaginae in the female. The arler}) to the bulb, a branch of which is usually of relative large size, is given off between the layers of the triangular ligament. It runs transversely inwards along the posterior border of the compressor urethra, and then turning forwards a short distance from the outer side of the urethra, pierces the anterior layer of the triangular ligament amd enters the substance of the bulb. It passes onwards in the corpus spongiosum to the glans where it anastomoses with its fellow and with the dorsal arteries of the penis. It supplies the compressor urethra muscle, Cowper's gland, the corpus spongiosum, and the penile part of the urethra. In the female this artery supplies the bulb of the vestibule. The dorsal artery of the penis passes forward between the layers of the suspensory ligament, and runs along the dorsal nerve immediately to its outer side, whilst it is sepa- rated from its fellow of the opposite side by the median deep dorsal vein. It supplies the superficial tissues on the dorsal aspect of the penis, sends branches to the corpus cavernosum, and its terminal branches enter the glans penis, where they anastomose with the arteries to the bulb. It also anastomoses with the external pudic branches of the femoral. The nerve supply of the bulbo cavernosus is from the perineal branches of the pudic nerve and its purpose to compress the bulb and corpus spongiosum and to assist in ex- pelling the fluid contained in the urethra. The muscular fibers which pass to the dorsum of the penis or clitoris may aid slightly in their erection either directly or by compressing the dorsal vein. The integument of the root of the penis is supplied by the ilio-inguinal and inferior pudendal nerves and the body and prepuce by the branches of the dorsal nerves. Branches of the pudic supply the bulbus urethra and mucous membrane of the urethra and each corpus cavernosus by a deep branch from the dorsal nerve. Perineal branches of the pudic, ilio inguinal, and sympathetic nerves from the hypo- gastric plexus control the erection of the penis and clitoris. Lymphatics of the Clans Penis. — The collecting trunks of the glands arise from a fine network which partly drains the network of the prepuce and the balanitic portion of the urethra. These collecting trunks are two or three in number. The exact point of origin is at the frenum, since a series of finer collecting trunks drain and converge at this point. Two or three trunks which drain the mucous membrane of the urethra also empty into the main collecting trunks. The course of the main collecting trunks is around the corona of the glands and from two to four collecting trunks and anastomose with those of the opposite side, which run parallel with the dorsal vein of the penis, and terminate in the pre-symphysical at the penile root. The cutaneous lymphatics of the penis are divided into two sets the lymphatics of the sheath, and the lymphatics of the prepuce. Lymphatics of the sheath have four or five collecting trunks. They differ in length. Those most anterior are longer. These collecting trunks take their origin from the dense lymphatic network of the prepuce. The collecting trunks pass around the lateral surface of the penis to the dorsal surface; after which they pass to the penile root, where they make a sharp turn outwards to the inguinal glands. Lymphatics of the prepuce originate from the fine network in the plicature of the skin of the preputial fold. They are also continuous from the lymphatics of the glands in the balanitic portion. The collecting trunks vary in number from, one to two, to a mul- tiplicity of collecting tmnks. Their course is along the dorsum of the penis, near the superficial dorsal vein. When more than one trunk exists they give off anastomosing branches along their course, at the Page Eishty-Five penile root. If only one trunk is present it may divide into two trunks, which are equal in size or it may continue without division to its limitation which is an inguinal gland. When several trunks exist they form two at the penile root. They usually terminate in the supero- internal group. Yet, however, they may also terminate in other glandular groups of this region. The collecting trunks are located just beneath the integument. ETIOLOGY. Anomalies, Diseases and Injuries. Male Erectile BodV- Anomalies. D"l Benign. iseases ^ ^;, ,•* J Malignant. Injuries. ANOMALIES. Anomalies of the erectile bodies may be congenital or acquired, primary or secondary, vary in position and relation to other tissues, the blood, nerve, and lymph supply more or less than normal and any one or more of its structures, wanting in part or their entirety. Shape may be regular or irregular, smooth or nodulated, curve upward, down- ward, to either side, taper excessively from the proximal or distal end. Blind Pouches may be congenital or acquired, single or multiple, vary in size, shape and location and contain mucus or serum. Shape may be excessively long or short, diameter vary greatly from end to end, single or multiple, position to the right or left of the median line, high or low, concealed in part or its entirety, within the scrotum, perineum, groin or upper thigh. DISEASES. Benign. Malignant. BENIGN. Ulcers may be congenital or acquired, primary or secondary, single or multiple, acute or chronic, due to trauma or infection in any tissue or portion of the erectile body, continue, cease to grow or disappear spontaneously. Syphilis may be congenital or acquired, acute or chronic, primary or seconda^y^ in the form of chancre, chancroid, gumma, single or multiple, vary in size, shape and location. Tuberculosis may be acute or chronic, primary or secondary, single or multiple, vary in size, shape or location in any tissue. Fibromata may be congenital or acquired, single or multiple, primary or secondary, in any portion of the gland, originate in any tissue and extend into the adjacent structures. Lipomata may be congenital or acquired, single or multiple, primary or secondary, round, oblong, smooth or lobulated in any of the fatty structures, vary in size, remain dormant, increase or diminish in size or disappear spontaneously. Adenomata may be congenital or acquired, primary or secondary, single or multiple, vary in shape, location, usually without pedicle, and in any tissue. Concretions may be congenital or acquired, primary or secondary, single or multiple, soft or hard, usually between the gleind and prepuce, vary in size, shape, and number in the body. Bon^ deposits may be congenital or acquired, primary or secondary, single or mul- tiple, hard or soft, vary in shape, size and location, involve a part or all of the organ, the walrus, raccoon, many monkeys, dog and many members of the negro race being examples. Page Eighty-Six Horn^ g;olP//is may be congenital or acquired, primary or secondary, single or mul- tiple, vary in size, shape and location, continue or cease to grow, or disappear spontaneously. Lymphangitis may be congenital or acquired, primary or secondary, acute or chronic, mild or severe. Lupus may be primary or secondary, vary in shape, size and position. Gangrene may be mild or severe, in any portion, with partial or complete loss of the organ, always acute. Elephantiasis may be congenital or acquired, primary or secondary, acute or chronic, from slight to enormous in size, usually general. Cysts may be congenital or acquired, single or multiple, primary or secondary, con- lain blood, pus, mucus or serum, originate in any of the structures, especially externally, rupture into the rectum, urethra, bladder, perineum, scrotum, vagina, uterus or peritoneal cavity. Fistulae may be congenital or acquired, single or multiple, primary or secondary, extend from the urethral canal through the cutaneous structures, connect with the rectum, vagina, bladder, peritoneal or uterine cavities or through the perineal body, several chan- nels existing at the same time. Phimosis may be congenital or acquired, primary or secondary, acute or chronic, partial or complete, with or without adhesions. Paraphimosis may be congenital or acquired, primary or secondary, acute or chronic. MALIGNANT. Carcinomata may be primary or secondary, usually primary, and single, in any tissue, especially the prepuce corona or distal end of the gland. Sarcomata may be primary or secondary, in any tissue amid portion of the glauid. INJURIES. Ruptures, lacerations, punctures, incisions and contusions may be the result of acci- dent or design, penetrating or non-pentrating, primary or secondary, smooth or irregular, longitudinal or circular, in any portion of the body. Fractures may be congenital or acquired, usually acquired, single or multiple, by accident or design, complete or incomplete, in any portion of the body. Dislocations may be congenital or acquired, forward, backward or to either side. SYMPTOMS. Symptoms pertaining to the erectile body in the male and female are very similar physiologically, tenderness, pain and general nervous disturbances being most prominent. Pain of any degree may be acute or chronic, primary or secondary, and sometimes due to conditions far distant to the erectile body. Adhesions and furuncles about the clitoris are not uncommon causes, but any disease or irritation may cause erection of this body, or it may be purely psychical, \vith or without frequent desire to urinate and the amount of urine increased. Cardio-vascular disturbances resulting from abnormal conditions of the male repro- ductive organs are more or less in evidence, especially with infections and advanced pros- tatic conditions. Those affecting the erectile body, testes, spermatic ducts and scrotum being not so highly manifested. Vascular symptoms of the male erectile body are induced by severe and prolonged pain, the pulse-rate varying from slow to rapid as the result of these causes but the rate and quality may change from time to time without any perceptible irregularity in the organ. Urinary disturbances are always present with any pathology or trauma that may exist in the erectile body of the male. The amount of urine may be greatly increased' or diminished and contain blood, pus, concretions or necrotic tissue and cause severe burning or tenesmus, or it may escape through one or more of the many forms of artificial openings. Page Eighty-Seven CHAPTER XIV. PROSTATE GLAND. ANATOMY. open into the prostatic Fig. 48. HE PROSTATE GLAND normally is composed of two lateral and a m.iddle lobe, the three combined being about the size and shape of a large horse chestnut, in the adult, and weighs about '/2 ounce. The middle lobe which is about the size of a pea is frequently absent while the lateral lobes vary in shape and size, one of which may be also absent. The three lobes are enclosed m a thin, firm, fibrous, capsule and the urethra and seminal ducts pass through the gland but often vary in their course. The two small yellow bodies about the size of a pea which lie beneath the anterior part of the membranous urethra close behind the bulb and are enclosed in the transverse fibers of the compressor urethra muscle, were discovered by Cowper for whom they are named. The prostate gland is composed of many fcllicles and muscular fibers in such a number as to form fifteen to twenty channels designated as secretary ducts lined with columnar epithelian and urethra. Page Eig-hty-Bight The prostatic muscle is supported upon the anterior wall of the bladder by fibers of the levator ani, which are also called levators of the prostate on the sides. Leuckhart states that in women there exists a true rudimentary prostate, consisting principally of mucous follicles and situated between the beginning of the urethra and the reflection of the vagina. Flodgson also states that Virchow admitted the existence of this body, found at the neck of the bladder, especially in old women. Most observers have held that the glandular portion of the prostate originates from the urethra and the stroma of the organ develops from a thickening of the genital chord, but Griffiths and Richardson who have made a detailed study of this gland say that no part is developed from the genital chord. The blood suppl]; is from the middle hemorrhoidal, inferior vesical and internal pudic artery while a large venous plexus surrounds it. Into this plexus veins of the penis open and communicate with the vesical plexus and drain into the iliac veins. These veins which become larger with advanced age, besides draining the dorsal veins, also drain those of the Fig. 49. — Bladder, prostate, seminal vesicles, vasa deferentia (Deaver). bladder, seminal vesicles and the rectum, and are continued as the prostatic vesical plexus, tributary to internal iliac veins. Nerve supply is from the hypogastric plexus in the form of sympathetic fibers asso- ciated with small ganglia along their course. Pacinian corpuscles are said to be con- nected with the sensory fibers (Piersol). Lymphatics of the prostate arise by fine capillaries arranged in the form of a net- work around each glandular acinus. From these periacinous networks, run larger ves- sels which pass towards the periphery of the gland, and form at its surface a second network, the peri-prostatic network, from which the collectors start. The latter which are symmetrically arranged on each side of the gland, may run in four different directions. A primary trunk starts from the posterior surface of the prostate, and runs on to the bladder in the triangle between the vasa deferentia. It ascends as far as the middle part of the postero-superior surface of the bladder, where it curves sharply outward, across Page Eighty-Nine the hypogastric artery, and terminates in the middle gland of the middle chain of the external iliac group. In its retro-vesical course, this trunk describes numerous curves; it may pass through some small interrupting glandular nodules (Schaltdriisen) close to the spot where it crosses the hypogastric artery. This ascending channel frequently consists of two trunks which then terminate in the middle and superior glands of the middle chain. A second collector arising like the preceding from the posterior surface of the pros- tate, accompanies the prostatic artery. Like the latter, it runs upwards, outwards and backwards, and terminates in one of the middle glands of the hypogastric group. In the neighborhood of the prostatic origin of this trunk, two or three small glandular nodules are almost constantly found. Ttpo or three other collecting trunks also start from the posterior surface of the gland, and run at first downwards, and then backwards. They enter the sacro-recto- genital aponeurosis, cross the lateral surface of the rectum, and then ascend on the an- terior surface of the sacrum. They do not all terminate in the same manner. The shorter and more external end in the lateral sacral glands, which as we have already seen, are usually situated internal to the second sacral foramen, the longer and more internal pass as far as the promontory to terminate in the glands situated there. Finally, from the anterior surface of the prostate may be seen a descending trunk which runs towards the pelvic floor, where it unites with the vessels coming from the membranous portion of the urethra. In company with the latter, it embraces the artery of the corpus spongiosum, and then runs with the internal pudic ; it finally terminates in a gland of the hypogastric group, situated on the intrapelvic portion of the trunk of the internal pudic artery. The descending prostatic channel, which was observed in the dog by Walker, has also been found in man by Marcille (three times in fifteen subjects). ETIOLOGY. Anomalies, Diseases and Injuries. Anomalies. P^. / Benign. Uiseases. S iv/r r . ^ Malignant. Injuries. ANOMALIES. Anomalies may be congenital or acquired, single or multiple, primary or secondary, vary in shape, number, position, size and relation to other tissues, or none at all but doubt exists about the total absence of prostatic tissue. DISEASES. Benign. Malignant. BENIGN. Adenomata may be congenital or acquired, single or multiple, primary or secondary, usually primary, in any portion of one or more glands, vary in size, shape, location, cease to grow, continue to increase in size, disappear spontaneously, undergo cystic or malig- nant chcinges. Papillomata may be congenital or acquired, single or multiple, primary or secondary, usually primary, in any portion of one or more glands, vary in size, shape, location, cease Pag-e Ninety to grow, continue to increase in size or disappear spontaneously, and are usually pedun- culated when upon the surface. Tuberculosis may be primary or secondary, acute or chronic, vary in size, shape and location in any tissue. SypInUs may be congenital or acquired, primary or secondary, acute or chronic, vary in size, shape, location, in any tissue in the form of gumma. Cysts may be congenital or acquired, primary or secondary, single or multiple, acute or chronic, contain blood, pus, mucus, serum, seminal fluid, dermoid material, eccliinococci, rupture into the bladder, urethra, rectum, perineum, peritoneal cavity, or through the over- lying soft structures anywhere upon the surface about the pelvis or upper thigh. Concretions may be congenital or acquired, primary or secondary, single or multiple, large or small, soft or hard, escape from the bladder into the prostate, rupture to pass into the rectum, urethra, perineum or peritoneal cavity. Foreign bodies may enter the gland through the bladder, rectal wall, urethra, peri- neum, skin, the overlying soft structures become encysted or pass into the rectum, urethra, bladder, perineum, peritoneal cavity or overlying soft structures. Fisiulae may be congenital or acquired, single or multiple, acute or chronic, open into the bladder, rectum, perineum, urethra, peritoneal cavity or soft structures and skin, vary in size, shape, and number. MALIGNANT. Carcinomaia may be primary or secondary, usually primary, single, or multiple in one or all of the three lobes and involves by extension one or all of the surrounding tissues. Sarcomata may be primary or secondary, single or multiplle, almost invariably single, usually originate in the body of the gland, and extends into the surrounding structures. INJURIES. Ruptures, punctures, incisions, may be primary or secondary, in the gland through the urethra, bladder, rectum, perineum or peritoneal cavity, by accident or design, and involve a part or all of the adjacent soft structures. SYMPTOMS. S]^mpioms, prostatic in character, are pronounced when extreme irregularities are present especially when the flow of urine is obstructed. They are often difficult to define because the gland is concealed within a capsule and because of the relation of the capsule to other important structures richly supplied ^vith nerve fibers, blood vessels and lymphatics. The earlier symptoms are especially difficult to de- fine but those advanced are more definite. Pain becomes more severe with advanced conditions but pain in the prostate may be reflected from sources far distant from the gland. The pain may be dull and heavy, of a bearing down character, at times resembling the sensation of burning with more or less urethral and rectal tenesmus. There is always local tenderness and when far advanced it may be general throughout the pelvis asso- ciated with general irritability, emaciation and exhaustion. Pain may be suprapubic, in the lumbar region, at times of urination or defecation, retention, tenderness, frequent urina- tion, all of which resemble those pertaining to stone in the bladder. All of these symptoms may indicate conditions other than prostatic. Page Ninety-One CHAPTER XV. COWPER'S GLANDS. it/Ov^T^i - Fig. 50. (Ayers.) OWPER'S GLANDS are situated between the two layers of the triangular ligament, anteriorly to the prostate gland. Normally there are two in number, but there may be only one. Discovered 1696. They are ovoid in shape just beneath the membraneous por- tion of the urethra, close to the mid-line on each side. They are the size of an ordinary pea, irregular and somewhat knobbed in shape. They are of a pinkish hue, firm imbedded in the fibers of the compressor urethra muscle. The ducts are 1 .5 mm. in diameter, 3.4 mm. in length. They open by small slit-like orifices on the lower wall of the bulbus urethra near the mid line. The ducts sometimes open into the urethra by a common orifice. They are homologous with the Bartholin glands in. the female and are accessory organs. TliQ blood supply are twigs from the arteries of the bulk, and the veins are tributary to those returning the blood from the bulbus spongiosum, which empty into the internal pudic. The lymphatic are afferents to the internal iliac lymph nodes. Besides anomalies (which is probably of little importance), the various forms of disease and growths may be found involving these glands. If so, they must play a Page Ninety-Two prominent role in symptomatology, especially mflammation due to gonorrhea, the most common form of disease. ETIOLOGY. Anomalies, Diseases and Injuries. Anomalies. Diseases | P,^"'^"- l^ Malirnant. Injuries. ANOMALIES. Anomalies may be congenital or acquired, primary or secondary, vary in size, shape, number and location or entirely absent. DISEASES. Benign. Malignant. BENIGN. Inflammation (Cowperitis) may be primary or secondary, acute or chronic, unilateral or bilateral, usually the result of gonorrheal infection, more frequent than suspected, and of more importance as an etiologic factor than accredited. Adenomata may be congenital or acquired, primary or secondary, vary in size, shape, number and location. Papillomata may be congenital or acquired, primary or secondary, vary in size, shape, number and location. Tuberculosis may be primary or secondary, acute or chronic, local or general, cease to grow or disappear spontaneously. Syphilis may be congenital or acquired, primary or secondary, acute or chronic, become arrested, continue to destruction or disappear spontaneously. Cysts may be congenital or acquired, primary or secondary, single or multiple, acute or chronic, vary in size, shape and rupture mto the urethra (its natural course), rectum, bladder, perineum or peritoneal cavity. Fisiulae may be primary or secondary, usually acquired, single or multiple, vary in size, shape and location, open into the urethra, bladder, prostate, rectum, perineum or peritoneal cavity. MALIGNANT. Carcinoma may be primary or secondary, single or multiple, vary in size, shape and location. Sarcomata may be primary or secondary, usually primary and single, vary in size, shape and location. INJURIES. Lacerations and contusions may be by accident or design, primary or secondary, single or multiple, through the urethra, or rectum and usually caused by the introduction of sounds. SYMPTOMS. S})mptoms of conditions within Cowper's gland have not been given due considera- tion because of their size and inaccessibility. Their exposure to infections is equally as great if not greater than the spermatic ducts beyond them, but their concealment in the deeper structures prevents any definite conclusions whatever bemg devolved from symptoms which they produce. They are no doubt similar to those resulting from genito-urinary and rectal conditions in general, but especially of the prostate and posterior urethra. It is therefore impossible to ascribe to Cowper's glands at this time, any definite symptomatology. Pase Ninety-Three CHAPTER XVI. TESTICLES. ANATOMY. held together by delic Fig. 51. (Deaver.) HE TESTES are two glandular organs which secrete the semen. They are slightly compressed ellipsoidal bodies, suspended in the scrotum by the spermatic cord, the left lower than the right. They each measure about 4j/2 cm. in length, 2 J/2 cm. in width and 2 cm. in thickness. In early foetal life they are in the abdomen, post-peritoneal. Before birth they descend into the scrotum through the inguinal canal, carrying along the various layers, nerves, blood vessels, etc. The framework proper consists of a stout capsule, the tunica albugima, which gives form to the organ and protects the sub- jacent glandular tissue. From the greatly thickened posterior portion of the tunica albuginea, numerous septa arise which pass forward and divide the organ into separate compartments (or lobules) each of which contains from one to three greatly convoluted seminiferous tubules ate vascular, intertubular connective tissue. Pas-e Ninety- Four Blood supply is from the spermalic artery which is a branch of the aorta. It is a long slender vessel entering upon the posterior border of the testis, where it imnnediately breaks up into many branches which enter the diastinum testis to become distributed along the septa and on the deep surface of the tunica albuginea. The veins issuing from the posterior border of the testis, form a dense plexus called the plexus pampiniformis, which finally pours its blood through the spermatic vein, on the right side, into the vena cava, on the left side the spermatic vein joins the left renal vein. (Cunningham.) Nerve supply for the testis accompanying spermatic artery and is derived through the aortic and renal plexuses from the tenth thoracic segment of the spinal cord. The afferent fibers from the epididymis appear to reach the spinal cord through the posterior roots of the eleventh and twelfth thoracic and first lumbar nerves. The arteries and nerves of the testis communicate with those on the lower part of the vas deferens, namely, with the artery of the vas and with twigs from the hypogastric plexus. Gerald Maichant laid great stress upon the sinuosities of these collecting trunks. They are caused by the penis alternating between the erect and flaccid state. Lymphatics of the testicles anastomose with those of the epididymis, and those of the visceral layer of the tunica vaginalis. They pass along the spermatic cord, in intimate relation with its blood vessels. The former are more superficial than the latter. In the lumbar region the lymphatics leave the spermatic cord and vessels, and as they do so they make a regular curve or an acute angle. On the right side they terminate in the juxta-aortic glands. One or two afferent trunks are received by the lowest gland, which is located just above the bifurcation of the inferior vena cava. One or two of these lymphatics also terminate in one-third of the cases, in the pre-aortic glands. On the left side these lymphatics terminate in three or four of the juxta-aortic glands. The latter are arranged in rows below the renal vessels. Sometimes, however, some of these lymphatics also terminate in the pre-aortic glands. The terminals of the left testicle are on a higher level than those on the right, except in one-third of the cases, when they are on the same level. ETIOLOGY. Anomalies, Diseases and Injuries. Anomalies. Diseases ^ P,^";^"- ( Malignant. Injuries. ANOMALIES. Anomalies may be congenital or acquired, single or multiple, primary or secondary, vary in size, location, shape and structure, partially or completely concealed within the abdominal wall, between the outer inguinal ring and scrotum, or one or both entirely wanting. DISEASES. Benign. Malignant. BENIGN. Orchitis may be congenital or acquired, primary or secondary, acute or chronic, local or general, unilateral or bilateral. Tuberculosis may be primary or secondary, single or multiple, acute or chronic, in one or both simultaneously, in any of their tissues, especially in the earlier statues, in the Payo Xinet\-Fi\-( primary form, confined to the gland or glands, or extend into their surrounding soft structures. Sy^philis may be congenital or acquired, primary or secondary, single or multiple, in- volve one or both glands, continue in its destruction, remain stationary, disappear spon- taneously or involve the overlying soft structures. ^^ Fibromata may be congenital or acquired, primary or secondary, single or multiple, vary in size, shape, and involve either one or both glands, in any tissue. Lipomaia may be congenital or acquired, primary or secondary, single or multiple, vary in size, shape, location and extend into the surrounding structures. Retraction may be congenital or acquired, primary or secondary, partial or com- plete, temporary or permanent, unilateral or bilateral. Hemorrhagic infarct may be congenital or acquired, primary or secondary, usually acute, vary m size, location and seventy. Cysts may be congenital or acquired, primary or secondary, acute or chronic, single or multiple, in one or both glands, originate in the cortex, the ducts, connect with the peritoneal cavity into w^hich they may discharge, rupture through the external and cutaneous structures, seldom if ever into the urethra, occasionally into the rectum, more frequently into the perineum, contain blood, pus, serum, dermoid material, or echinococci, one or more simultaneously. Fistulae may be congenital or acquired, primary or secondary, single or multiple, con- nect with the peritoneal cavity, urethra, rectum or perineum, one or all, at the same time, become closed spontaneously, remain indefinitely, vary in size or course or rupture through the soft structures. MALIGNANT. Carcinomata may be primary or secondary, usually epitheliomatous and vary in size, shape and number. Sarcomata may be primary or secondary, vary in location, and in any tissue. INJURIES. Foreign bodies invariably enter the gland through the overlying soft structures. They may be single or multiple, vary in size, location and character, become encysted, remain permanently, escape into the scrotum where they may remain, or through which they may afterward escape. Ruptures, punctures, lacerations, incisions, and contusions may be the result of accident or design, primary or secondary, single or multiple, involve any portion of one or both glands to the degree of functional disturbance or destruction. SYMPTOMS. Symptoms associated with testicular variations are simple in character, therefore easy to determine when compared to the deeper structures and organs of the perineum. Pain is not always confined to these glands because of their inhibition being by branches of the pudic which supplies so generally the perineum. The milder forms of testicular conditions usually produce local symptoms, while the more aggravated forms cause both local and general symptoms, severe in character because all of the reproductive and urinary organs are likewise disturbed, especially with the acute form of disease. Page Ninety-Six CHAPTER XVII. SPERMATIC DUCTS. Epididymis. Vas Deferens. Seminal Vesicles. Ejaculatory Ducts. ANATOMY. 0-tti drtpry of rij> Cefprerrs. LRllCAi SECTION Of TCSTICLl SHOWING THE A)!fiANG[M[Nrt)r THE DUCT3 "fSTtiE AND ihOj'Mii Fig. 52. (Deaver.) PERMATIC DUCTS are two tortuous canals, one on either side, that connect the epididymi \vith the urethra and thus provide channels for the escape of the products of the sexual glands. Each of these ducts is divided into the vas deferens and its am- pulla and the ejaculatory duct, at the upper end of the latter the spermatic duct is connected with the seminal vesicles. The spermatic ducts described by Deaver are pale and as- sociated with pale medullary fibers from the hypogastric plexus of the sympathetic nerve, for involuntary muscle fibres accompany a greater part of the duct as a differential plexus, and the nerves of the testis and epididymis are sympathetic fibers for the walls of the blood vessels which they accompany as the spermatic and the differential plexuses that surround the corresponding arteries. They have been traced into the muscular tissue and the mucosa. Within the muscles they form the dense myospermatic plexus. I'iige Ninety-Seven Epididymis. The greatly convoluted beginning of the seminal ducts, covers the entire posterior border and outer surface of the testis. Blood Supply. Principally the deferential vessels, the spermatic emd the cremasteric arteries. ^ Nerve Supply. Spermatic and deferential plexuses which surround the correspond- ing arteries. Vas Deferens. This tube extends from the epididymis to the ejaculatory duct and includes almost the entire length of the spermatic duct. The ejaculatory duct is formed by the union of the ducts of the corresponding seminal vesicles and vas deferens, and empties into the urethra. Blood supply of spermatic ducts is chiefly the deferential from the internal iliac. It also receives a branch from the middle hemorrhoidal. Lymphatics of the P'as Deferens. The origin of the collecting trunks of the deferens is supposed to be from two net works, viz. : the muscular and mucous. Some doubt, how- ever, exists since the latter has never been injected. These collecting trunks terminate in external retro-crural gland and in the middle chain of the external iliac glands. Lymphatics of the seminal vesicles arise from a network, which is formed by the anastomosis of two networks. One originates in the mucous coat, while the other takes its origin in the muscular coat. There are Two Collecting Channels. They anastomose with those of the urinary bladder, and also vary much from those from the prostate. A posterior gland of the ex- ternal iliac group, and a hypogastric gland are the terminals. Anomalies, Diseases and Injuries. Anomalies. Df Benign. iseases -I ,,, ,. t_ Malignant. Injuries. ANOMALIES. Anomalies may be congenital or acquired, single or multiple, primary or secondary, partially or completely absent, long, short, large, small, sacculated, patulous, partially or completely closed, for a short or long period, or they may never become patulous. DISEASES. Benign. Malignant. BENIGN. Inflammation may be primary or secondary, acute or chronic, involve a part or all of the duct. Tuberculosis may be acute or chronic, primary or secondary, single or multiple in any portion, cease, or continue to develop, disappear spontaneouslj% or become perma- nently destroyed. Syphilis may be congenital or acquired, primary or secondary, single or multiple, involve any portion, continue to develop or disappear spontaneously. Cysts may be congenital or acquired, acute or chronic, primary or secondary, single or multiple, gradually or suddenly disappear by draining into the urethra or rupturing into the surrounding soft structures to become absorbed, or through them, externally upon the skin, into the perineum, scrotum, rectum, bladder or peritoneal cavity. Page Ninety -Eight Fistula may be congenital or acquired, primary or secondary, single or multiple, acute or chronic, through the external soft structures, into the perineum, rectum, urethra, or peri- toneal cavity and several channels connect two or more organs or cavities. Fibromata may be congenital or acquired, primary or secondary, single or multiple in any portion of the lube, vary in size, shape and number. Lipomata may be congenital or acquired, primary or secondary, single or multiple, remain stationary, continue to grow or disappear spontaneously. Concretions may be congenital or acquired, primary or secondary, single or mul- tiple, semisolid or hard, vary in size, shape and location, remain or escape into or through the surrounding soft structures. Strictures may be congenital or acquired, primary or secondary, single or multiple, anywhere in the ducts, remain temporary or permanent (usually permanent) with loss of function. MALIGNANT. Carcinomata may be primary or secondary (usually primary) single or multiple, vary in location, involve any portion of one or both at the same time, though it is exceedingly rare to have the two affected simultaneously. Sarcomata may be primary or secondary, single or multiple (rarely multiple) and affects any portion of the duct. INJURIES. Injuries may be contusions, lacerations, incisions, or punctures, by accident or de- sign, partially or completely destroy function and vary in degree and location. SYMPTOMS. Symptoms. Seminal Vesicles. Local. Inflammatory, functional, neurotic, reflex. General. Fuller says : Tenderness is referred to the lateral hypogastric region over the sac, to the lower back or to the deep perineum. Pain intensified by acts of urination and defecation, upright positions and exercise, when severe. Pain along cord, into testicle, along the urethra, down the thighs, up toward the kidneys or into the rectum at onset, sexual function is excited, strong and persisting erec- tions, often painful chordee, the latter suggesting anterior urethritis. Frequent painful emissions, occasional bloody ejaculations. Frequent micturition and tenesmus suggesting involvement of bladder. All of these may exist without cystitis. Rectal tenesmus and straining at conclusion of the act of defecation or urination. Bladder disturbances become increased with partial or complete retention all due to distention of the duct because symptoms gradually subside with drainage. Symptoms of spermatic duct involvement are not altogether determined because of their concealment within the deeper structures and because of their intimate relation with the prostate, urethra and bladder above, and in front, rectum behind and perineum below. Neurotic sensations with the penis, testicles and scrotum may exist in the form of pain and retraction. General symptoms are neurotic and mental to the degree of insomnia increased or de- creased sexual desire. Symptoms of conditions involving the vas deferens like other external genitalia may not be easily defined. Page Ninety-Nine CHAPTER XVIIl. SCROTUM. ANATOMY. "v ^^ fe^ y\ ^^ SCROTUM, sac-like in appearance, is composed of muscular W Is. fl ^ fibers known as the dartos muscle, situated in the superficial .^^^ h^>i^>, fascia and skin, containing sweat and sebaceous glands with their ducts and areolar tissue, in all of which there is an absence of fat. The tissue within the median line known as the raphe is more dense and capable of contraction. Blood supply is from the superficial perineal branches of the internal pudic arteries from behind and the external putic branches of the femoral artery above and in front. Nerves. The scrotum in the male and labia in the female aie sup- plied with nerves (Deaver) from the lumbar plexus, which go to the front and sides of the scrotum including cutaneous from the genital branch of the genito-crural nerve usually reinforced by branches from the ilio-inguinal that end in the skin in the vicinity of the root of the scrotum, emd the sacral plexus which supplies the posterior surface of the scrotum and are from the perineal or inferior pudendal branches of the small sciatic nerves, and the anterior or external superficial perineal branches of the pudic nei'ves, sympathetic fibers accompanying the cutaneous nerves for the dartos muscle. Deaver also states that scrotal and labial pain may be due to pressure upon the trunk of the inferior pudendal nerve, the small sciatic or that portion of the sacral plexus or spinal cord from which the filaments arise; while on the other hamd, pressure upon the terminal part of the inferior pudendal may give rise to pain referred to the back of the thigh. External L'^mphaiics in the Male. Collecting trunks of the scrotum are divided into the superior, and inferior. There are ten or fifteen trunks on each side which form a dense network. Superior collecting trunks originate on that part of the scrotum which is a continuation of the penile raphe. They pass upward in a vertical direction to the root of the penis, where they turn obliquely outwards, running parallel with the collecting trunks of the penis. After they cross the spermatic cord they tenninate in the supero-internal super- ficial inguinal glands. Inferior collecting trunks originate below and posterior to the superior collecting trunks. They pass to the lateral parts of the scrotum in an upward and outward direction to the lateral part of the scrotum, from whence they enter and follow^ the cruro-scrotal groove for a brief distance, and then pass outwards, terminating in the inferior internal glands. Within the pre-symphysical plexus are several glandular nodules. This plexus is drained by a number of collecting trunks, which pass into the inguinal and crural canals. One inguinal collecting trunk passes into the spermatic cord, and terminates in the external retro-crural gland, as the inguinal collecting trunk enters the inguinal canal, it usually gives off a small glandular nodule. Page One Hundred The crural collecting lrunl(s are three or lour in number. They pass transversely outwards under the femoral aponeurosis and anterior to the pectineus muscle. At first they are in a single bundle, but after a short distance they diverge in a vertical direction, and terminate at three different points. The lowest terminates in the deep inguinal gland, which is in the crural canal and internal to the femoral vein. A second terminates in the gland of Cloquet, while a third terminates in the internal retro-crural gland, which is on the external iliac vein within the pelvis, ETIOLOGY. Anomalies, Diseases and Injuries of the Scrotum. Anomalies. Diseases { ^5";.§"- l^ Malignant. Injuries. ANOMALIES. Anomalies of the scrotum may be congenital or acquired, primary or secondary, large or small, short or long, unilateral or partially or entirely absent. DISEASES. Benign. Malignant. BENIGN. Ulcers may be congenital or acquired, primary or secondary, single or multiple, acute or chronic, vary in size and shape, in any tissue or locality, become arrested, con- tinue to grow or disappear spontaneously. Lipomata may be congenital or acquired, primary or secondary, single or multiple, vary in size and shape, in any portion of the scrotum. Fibromata may be congenital or acquired, primary or secondary, single or multiple, anywhere in the scrotal tissue, vary in size and shape, remain stationary, continue to grow or disappear spontaneously. Papillomata may be congenital or acquired, primary or secondary, single or multiple, vary in size and shape, anywhere upon the cutaneous surface, remain stationary, continue to increase in size and number, or disappear spontaneously. Tuberculosis may be primary or secondary, acute or chronic, single or multiple, con- tinue to grow, disappear spontaneously, and appear anywhere in the scrotal structures. S\)philis may be congenital or acquired, primary or secondary, single or multiple, anywhere in the scrotal tissues, in the form of chancre, eruption or gumma. Foreign bodies enter from without, vary in number, character and extent of penetra- tion, encysted, remain indefinitely without causing serious trouble, infected and expelled, complicated with injury to the testicles or spermatic ducts. C^sts may be congenital or acquired, single or multiple, acute or chronic, primary or secondary, contain blood, pus, serum, sebacious matter, dermoid material or echinococci, vary in size, rupture externally through the cutaneous structures, into the perineum, rectum, bladder or into the soft structures of the upper thigh, perineum or groin. Fistula may be congenital or acquired, primary or secondary, single or multiple, acute or chronic, penetrate the cutaneous structures, the perineum, urethra, bladder, sper- matic duct, rectum or peritoneal cavity. Pase One Hundred One MALIGNANT. Carcinomaia may be primary or secondary, vary in size, shape and location and be in any of the structures usually within the skin. Sarcomata less frequent, primary or secondary, vary in size, shape and location and originate in any of the structures. INJURIES. Lacerations, punctures, incisions, and contusions are the result of accident or design, primary or secondary, vary in number, degree and location, sharp or ragged in any tissue or location. SYMPTOMS. Symptoms scrotal in character are pain, tenderness and induration, mild or severe, local or general or both, but pain and tenderness may exist in scrotal structures free from disease or injury, because of their richness in sensitive nerve fibers and intimate relation with other structures equally well supplied. Each of these symptoms may be primary or secondary to conditions within the struc- tures contained within the sac or tissues far distant to it, especially the prostate, urethra, bladder or rectum. Page One Hundred Two CHAPTER XIX. VAGINA. ANATOMY. ^V >-^ ""^^ /^ HE VAGINA originally the cloacal chamber, contains the clitoris, ^1^ \l ^ external urinary meatus and the cervix uteri with its opening sur- C>y> 5^S— ^^ rounded by mucous membrane, deeply folded to form the major and minor labiae which form its outlet. The hulho cavernous in the female has been termed the sphincter vaginae, the two muscles of opposite sides are v/idely sepa- rated from each other by the vagina which they surround. They arise from the central tendon of the perineum, pass forward invest- ing the bulbi vestibule and are lost in the fascia covering the cor- pora cavernosa and the dorsal surface of the clitoris. Vaginal mucous membrane has a stratified scaly epithelium and is corrugated by a number of transverse ridges called rugae vaginales. There is also a transverse rugae on the anterior and posterior wall of the vagina especially seen in young subjects in the lower part of the vagina. Within the mucous coat, nodules of lymphoid tissue are found, and the vaginal wall is surrounded by loose vascular con- nective tissue, containing many large communicating veins. The blood supply is mostly from the branches of the vesico-vaginal artery, vaginal branch of the uterine artery, vaginal branches of the middle hemorrhoidal and internal pudic arteries. The veins surrounding the vaginal wall drain their contents into the internal iliac vein. Nerves supplying the vagina, according to Piersol, are from the hypogastric sympa- thetic plexus through the pelvis and from the second, third and fourth sacral nerves. The immediate source of the sympathetic fibers is from the cervical ganglia at the side of the neck of the uterus from which in association with the sacral branches, twigs pass to and from each side of the vaginal plexus that embraces the vagina and filaments chiefly for the involuntary muscle of its walls and blood vessels. Sensory fibers are few in the vaginal mucous membrane so that the upper vagina has but slight sensibility though it is greatly increased as the vaginal orifice is approached by the pudic fibers which supply the mucous membrane and which send motor fibers to the striated muscle surrounding the entrance. Lymphatics of the Female. The female sexual organs are external and internal, and have their corresponding lymphatics. Therefore, the lymphatics of the external and internal genitalia are considered separately. The lymphatics of the vulva arise from a net- work which is arranged in several planes and which covers the forchette, meatus urinarius vestibule, labia minora, labia majora and clitoris. Drainage of this meshwork is accom- panied by collecting trunks which take an upward and forward direction to the mons veneris where they change abruptly into a transverse direction towards the superficial inguinal glands. The collecting trunks arising from the posterior two-thirds, take an up- ward and outward direction before reaching their tenninal glands. The termination of the vulva glands is the superior-internal group, inferior-internal group or one of the ex- ternal groups. They usually, however, terminate in the former group, rarely in the latter group. Page One Hundred Three Lymphatics of the Vagina. Two kinds of tissue are drained by the vaginal lym- phatics: mucous membrane cind muscular respectively. Those which drain the mucous membrane are beneath the epithelium, and are com- posed of a very fine and dense network. The muscular lymphatics are the coarser ftf the two. The collecting trunks of the vaginal lymphatics are divided into three groups, viz. : the superior, middle and inferior group. The superior group drains the upper third of the vagina. Two collecting trunks arise from this group. One arises anterior to the cervix, while the other arises posterior to the cervix. The anterior collecting trunk, after passing upward, outward and anterior to the ureter, receives several cervical trunks and terminates in the middle gland of the middle chain of the external iliac group. ■ The posterior collecting trunk takes an upward and outward direction and ter- minates either in the middle gland of the middle chain of the external iliac group, or in the posterior gland of this group. The middle group drains the middle third of the vagina. Its direction is upward, backward and outward, and corresponds to the direction taken by the vaginal artery. The termination is a gland of the hypogastric group, which is located in the hypogastric space at the origin of the vaginal artery. The inferior group collecting trunks arise in the third of the recto-vaginal septum. first — These collecting trunks descend, then pass outward and backward, after which they pass upward into the cavity of the sacrum, internal to the sacral foramen and terminate usually in the glands of the promontory group. Occasionally they terminate in the lateral sacral glands. ETIOLOGY. Anomalies, Diseases and Injuries. Anomalies. T-N- r Benign. Diseases | ^^^^^^,^ Injuries. Anomalies. A part or all of the vaginal tissues may be absent. The cavity large or small, irregular in shape, entirely absent, septinated, deep, shallow or narrow and have one or more external or internal openings- those internal entering the rectum, bladder or peritoneal cavity. DISEASES. Benign. Malignant. BENIGN. Vaginitis may be primary or secondary, acute or chronic, mild or severe and involve a part or all of the vaginal mucosa. Ulcers may be congenital or acquired, primary or secondary, single or multiple, acute or chronic, vary in size, shape and depth, in any tissue or portion of the vaginal wall, cease, continue to grow, or disappear spontaneously. Papillomata may be congenital or acquired, single or multiple, primary or secondary, in any portion of the mucous membrane, especially upon the muco-cutaneous border, vary in size and shape, usually pedunculated, cease, continue to grow or disappear spon- taneously. Page One Hundred Four Adenomata may be congenital or acquired, primary or secondary, single or multiple, vary in size, shape and location, have a broad ba^e or pedicle, cease, continue to grow or disappear spontaneously, though such a resolution seldom occurs. Fibromata may be congenital or acquired, primary or secondary, usually primary, single or multiple, vary in size and shape, in any portion of the vaginal tissue, especially the muscularis. Lipomata may be congenital or acquired, usually primary, single or multiple, vary in size, shape, anywhere in the vaginal tissues. Cysts may be congenital or acquired, single or multiple, primary or secondary, acute or chronic, in any tissue or portion of the vaginal wall, rupture into the vagina, rectum, perineum, urethra, bladder, uterus or peritoneal cavity, remain undisturbed, contain blood, pus or serum, urine, echinococci or dermoid material. Fistula may be congenital or acquired, primary or secondary, single or multiple, acute or chronic, enter the vagina, rectum, urethra, bladder, uterus, peritoneal cavity, pass into or through the perineal body or soft structures of the upper thigh. MALIGNANT. Carcinomata may be primary or secondary, single or multiple, usually primary ajid single, originate in any tissue or portion of the vaginal wall. Sarcomata may be single or multiple, primary or secondary, vary in size and originate in any tissue or portion of the vaginal wall. INJURIES. Lacerations, incisions, punctures, may be by accident or design, single or multiple, primary or secondary, longitudinal or circular, partial or complete, in any portion of the vaginal wall. Foreign bodies may be by accident or design, single or multiple, enter through the vaginal outlet, rectum, perineum, bladder or peritoneal cavity and escape through their outlets. SYMPTOMS. The many conditions that may exist within the vagina render it productive of a great many local and general physiologic symptoms, very similar in character. Local pain, tenderness and induration and general nervous disturbances are of the greatest consideration and probably more definite in this than the other reproductive organs of the female. It is only the milder forms of vaginal conditions that produce local symptoms alone, but they often produce rectal or urinary disturbances of an aggravated form, but these two tracts seldom escape the influences of the more severe conditions, especially when they are in close proximity. Page One Hundred Five CHAPTER XX. BARTHOLIN GLANDS. ANATOMY. J^tl^7tc^.£J^ ^cuu^<^. Fig. 53. ARTHOLIN GLANDS in the female are the homologues of Cowper's glands in the male. They are a small pair of organs situated one on either side of the vaginal orifice, behind the bulbus vestibuli and about the middle of the base of labium major. The duct merges from the anteromedial border of the gland. It is a small tube about 2 mm. in diameter and about Yl cm. long, and opens into the vaginal orifice between the nymphae cind the hymen. Its structure corresponds to the mucous tubo-alveolar type, the small component lobules however, being separated by fibro- muscular tissue, the terminal compartments are lined by columnar epithelium and contain numerous goblet cells. The main duct sometimes has ampulary enlargements. The secretion of the gland is whitish in color and viscid. Blood Suppl]). The arteries supplying this gland are twigs given off from the bulbar branch of the internal pudic. The veins are tributaries chiefly to the internal pudic but also communicate to the trunks of the vestibular bulb and the vagina. Page One Hundred Six Nerves are very numerous and include sympathetic fibers and twigs from the pudic. Lymphatics. The lymphatics join those of the vagina and rectum that are afferents of the internal iliac nodes. ETIOLOGY. Anomalies, Diseases and Injuries. Anomalies. Diseases ! P5";.g"- ( Malignant. Injuries. ANOMALIES. Anomalies. The glands of the two sides often vary in size and may be asym- metrically placed. The ducts may be double and the lobules so separated that the usual gland mass is replaced by isolated divisions or sometimes seemingly wanting on one or both sides. DISEASES. Benign. Malignant. BENIGN. Inflammation may be primary or secondary, acute or chronic, unilateral or bilateral and vary in degree. Papillomata may be congenital or acquired, primary or secondary, vary in size, number, shape and location. Adenomata may be congenital or acquired, primary or secondary, vary in size, shape, number and location. Fibromata may be congenital or acquired, primary or secondary, vary in size, shape, number and location. Cysts may be congenital or acquired, primary or secondary, acute or chronic, contain blood, pus, or serum, vary m size, shape, number and location, rupture through the cu- taneous structures, their natural course, into the vagina or rectum. Fistula may be congenital or acquired, primary or secondary, acute or chronic, single or multiple, vary in size, shape, length, open through the skin into the vagina or rectum. MALIGNANT. Carcinomata may be primary or secondary, vary in size, character, shape, location and rate of growth. Sarcomata may be primary or secondary, vary in size, shape, character, location and rate of growth. INJURIES. Incisions, punctures, contusions may be accidental or induced, primary or secondary, vary in degree and severity. SYMPTOMS. Symptoms such as pain, tenderness, redness and induration are most prominent. They may vary in degree and severity, local or general in their manifestations, and when gen- eral, are difficult to recognize. Page One Hundred Seven CHAPTER XXI. CLITORIS. ANATOMY. ^JLijbsyi^ Fig. 54. VS. (^ rJ) j\ ^^ ERECTILE BODY (clitoris in the female) , is the analogue jpj I J. Ji W of the penis in the male and is therefore to be considered much S-vfH K^\^^ in the same manner symptomatically. It is buried in such a manner beneath the labia that only its small conical anterior end and the lower vertical ridge of integument over the body appear when the labiae are separated. Blood Supply. The vessels supplying blood to the clitoris correspond with those of the penis but are smaller and the same arrangement is found with the veins. Nerve supply in its derivation and distribution is the same as found in the penis, being from the sympathetic system for the walls of the blood spaces and from the pudic nerves. The dor- sal nerve is relatively larger and supplies the integument of the glans and prepuce with fibers connected with special sensory end organs (Piersol). Clitoris. The lymphatic glands of the prepuce terminate in the superficial inguinal glands. Those of the glands clitoris resemble the lymphatics in the male. Their origin is composed of a network which empties into several collecting trunks. They pass along the dorsum of the clitoris to a point anterior to the symphysis, where in their union the pre- pare One Hundred Eight symphysical plexus is formed. Two collecting find their origin in this plexus. One made up of a small chain of glandular trunks passes along the canal of the neck, beneath the round ligament to the retro-crural glands. The other trunk runs towards the canal of the neck and terminates in the gland of Cloque, the retro-crural and deep inguinal glands. The clitoris has five times as many nerves as the penis and is supplied with sympathetic nerves which are freely anastomosed with the cerobrospinal nerves. S\)mf}toms such as pain, tenderness and general sexual irritability are most common and important. The existence of pathology of any kind within or about the clitoris will cause irritation of the sensory nerve fibers which it contains and consequently many ag- gravated general disturbances, such as headache, nausea, vomiting and sexual desire (See Chapter Male Erectile Body.) Page One Huiulreil Nine CHAPTER XXII. UTERUS. ANATOMY. f^ ^rnm^ ^^ j^ HE UTERUS constitutes in weight a larger amount than all of ^^ 1^ f / (^ ^^^ other reproductive organs in the female, and because of this \^j^ 5x0^, ^^ ^^ probably more frequently the seat of pathology, especially with the addition of pregnaint conditions. It must, therefore, play a prominent role in symptomatology. Blood supply is from the two uterine, each a branch of the internal iliac that accompanies the ureter along the pelvic wall, behind and below the ovarian fossa, to the attached border of the broad ligament beneath which it passes in its course to the ureters. As it is not necessary to describe in further detail the blood supply of this organ the subject will be concluded by reference to its intimate blood relation to the entire uro-genital and rectal tracts. (See Piersol, pp. 2009-2010.) Uterine nerves are large and for involuntary muscles and derived from the sympathetic system, the (utero-vaginal subdivisional) of the pelvic plexus, but directly from the second, third and fourth sacral spinal nerves. The utero-vaginal plexus divide into two parts, the smaller for the posterior, and the lateral parts of the uterus. The larger consists of a chain of small ganglia along the cervix and vaginal vault. Sympathetic nerves supply involuntary muscular walls of the uterus and tubes so that irritation from the generative organs travels to the abdominal brain by way of the ovarian and hypogastric plexuses. Uterine and tubal neuralgia is thus explained. Lacera- tion of the cervix pathologic in character for five years has been described by Sutton as being the cause of confirmed neurasthenia. Lymphatics of the Uterus. The uterine lymphatics originate in the mucous mus- cular and peritoneal coasts respectively. A network is formed by their anastomosis in the sub-peritoneal cellular tissue. The collecting trunks number four or five. The networks which originate at the cervix or corpus uteri are continuous, yet the cervical or corporal collecting trunks are considered separately. Cervical collecting trunks number from four to eight. They form the large lymphatic knot after leaving the cervix. This knot is called the juxta-cervical knot, it is often absent in the new-born, but alv/ays present when pregnancy exists. The cervical collecting trunks are subdivided into three groups, viz. : primary, secondary and lateral sacral groups. Primary Croups. There are two or three collecting trunks in the primary group, they converge towards the lateral portions of the corpus-uteri. They usually pass upward and anterior to and above the ureter. Occasionally their course is posterior and sub-ureteral. After accompanying the uterine artery for a short distance, the lymphatics leave the uterine artery and pass up the lateral wall of the pelvic cavity internal to the hypogastric artery in the adult, cross it in the foetus. They terminate in the middle and superior gland of the middle chain of the external iliac group. The juxta-cervical gland was first discovered by M. Lucas Championniere. It is occasionally found as an interrupting glandular nodule by the side of the cervix. Revnier Page One Hundred Ten "is of the opinion that the juxta-cervical gland is an hypertrophied gland due to a patho- logical process." Secondary) or hypogaslr'ic group originates on the same level as the primary group. It passes posteriorly to and below the ureter after which it passes upward, backward and outward terminating in a gland of the hypogcistric group on the anterior surface of the hypogastric artery on a level with the uterine and vaginal arteries. The lateral sacral group is composed of two or three collecting trunks which originate on the posterior cervical surface, after which they pass backward and continue across the lateral part of the rectum through the utero-sacral ligaments, from which they pass upward into the cavity of the sacrum. 1 wo terminals, the lateral sacral and the promontory glands. The former receives the external or shorter collecting trunks, while the latter receives the internal or longer collecting trunks. Collecting trunks of the corpus uteri are three in number, one primary and two ac- cessory collecting trunks. The primary collecting trunk subdivides into four or five small collecting trunks which originate below the uterine cornu. From their origin their course corresponds to the termmal segment of the uterme artery, after which they pass beneath the ovary to be joined by the ovarian ligament. As they continue in an upward direction towards the lumbar region, they pass around the blood vessels and with them cross the hilum of the kidney, then turn acutely and descend to the juxta-aortic glands. Some how- ever, may terminate in the pre-aortic group. Accessory trunks are two in number, viz. : primary and secondary. The primary trunk may be composed of one trunk or be subdivided into two trunks. Just below the uterine cornu is their point of origin. They pass outward and terminate in the middle chain of the external iliac group. This chain therefore receives cervical and corporeal lymphatics. Secondary collecting trunlf is difficult to trace to its termination, which is the super- ficial gland of the supero-internal group. Infections are carried upward by the retro-peritoneal glands to the thoracic duct frorn the uterus. ETIOLOGY. Anomalies, Diseases and Injuries. Anomalies. Diseases f P/^/.S"" ■\ Malignant. Injuries. ANOMALIES. Anomalies may be congenital or acquired, single or multiple, primary or secondary, vary in form, number and position, number of cavities or the entire absence of a cavity. The cervix may be long or short, small, irregular in shape, diameter, position, septinated, contain more than one canal, entirely absent (uterusacoulis) , open into the bladder, urethra, rectum or peritoneal cavity. [(See Anomalies of the Uterus) (Ricketts) Cin. Lancet Clinic (xlvii., page 554.)] DISEASES. Benign. Malignant. BENIGN. Endometritis may be primary or secondary, acute or chronic, local or general, mild or severe. Ulcers may be congenital or acquired, primary or secondary, single or multiple, acute or chronic, vary in degree, in any tissue or portion of the uterus, cease or continue to grow or disappear spontaneously. Fibromata may be congenital or acquired, primary or secondary, single or multiple. Page One Hundred Eleven pedunculated, hard or soft, vary in shape or size, in any portion of the uterine wall, at- tached to any of the abdominal viscera or abdominal w^all, become cystic, rupture into the uterine or peritoneal cavity, rectum, vagina or bladder. Papillomata may be congenital or acquired, primary or secondary, single^or mul- tiple, vary in size or shape, with or without pedicle, anywhere upon the external or in- ternal surfaces. Adenomata may be congenital or acquired, primary or secondary, single or multiple, vary in size and shape, with or without pedicle (usually without), anywhere upon the external or internal surface. Pregnancies may be normal or abnormal, single or multiple, become attached any- where upon the mucous surfaces or upper cervical canal, escape through the cervical canal, uterine wall into the rectum, intestinal canal, bladder, peritoneal cavity, Hfe of the foetus become extinct during any period of development, and the body remain indefinitely within the uterine cavity. Procidentia may be congenital or acquired, primary or secondary, vary in degree from slight to complete, return spontaneously to the normal position where it may remain indefinitely, or descend to ciny degree at any age and remain without ever having been impregnated, C^sts may be congenital or acquired, primary or secondary, single or multiple, acute or chronic, contain blood, pus, serum, urine, feces, echinococci, dermoid or colloid material, rupture into the uterus, bladder, rectum, peritoneal cavity, intestmal canal or externally through the skin or perineum. Fistula may be congenital or acquired, primary or secondary, single or multiple, acute or chronic, enter the bladder, uterus, rectum, peritoneal cavity, intestinal canal, perineum or pass through the external cutaneous structures. MALIGNANT. Carcinomata may be primary or secondary, single or multiple, in any tissues of the uterine body, especially the cervix. Sarcomata may be primary or secondary, single or multiple, hard or soft, in any of the tissues of the uterine body. INJURIES. Lacerations, punctures, and ruptures may be complete or incomplete, the result of acci- dent or design, from within or without, single or multiple, longitudional or circular, pene- trate into the peritoneal cavity, bladder, vagina, rectum, the overlying soft structures, or indirectly into the intestinal canal, blood vessels, ureters or Fallopian tubes. Foreign bodies may be by accident or design, single or multiple, vary in character, enter through the vaginal and cervical canals, bladder, rectum, or peritoneal cavity, the overlying soft structures or make their exit through these structures. SYMPTOMS. Symptoms ascribed to the uterus highly dominate the adjacent organs and soft struc- tures because of richness in sensory nerve fibers from the pudic and their coalescence with sensory fibers from the same source. The same group of symptoms are manifested with all and probably to the same de- gree throughout their existence whether they be mild or severe. This organ normally being the largest of the perineal and pelvic structures, and varying so greatly in size during pregnancy and disease, and possessing such a great blood, lymphatic and nerve supply, places it first in variety of pathology and symptomatology. It must also be the greatest factor in their complications. Local manifestations such as pain and tenderness are most prominent and may be more readily defined than other pelvic organs when involved without the manifestations of chill, headache, shock, perspiration, nausea and vomiting. The various forms of uterine pregnancies are without doubt the more common ex- citing causes of these manifestations. Next in frequency are accidents incident to preg- nancy, but uterine pathology of any kind may cause similar manifestations. Page One Hundred Twelve CHAPTER XXIII. OVARIES. ANATOMY. '>^ vr''^ Fig. 55. — Ovary and Blood Vessels (Kelley). ^(il (T) A\^^ normal ovary is about the size of a large almond ^)1. 4v 7 ^^-^^'' ^^ connected with the broad ligament by peritoneal folds - />H K\N-/, though not firmly fixed in any definite place. The upper end of the ovary is termed the tubal pole as it is more intimately con- nected with the Fallopian tube. The lower end is termed the uterine pole because it is connected with the uterus by a fibrous cord known as the ovarian ligament. The anterior border is termed the hilum of the ovary. Ovarian is the only tissue capable of regenerating itself or any other tissue of the body. It has been known to reproduce functional ovarian tissue, muscle, fat, tendon, cartilage, bone, teeth and hair and parts of various organs. It is, therefore, important that all ovarian tissue should be removed when menstruation is to be prevented, or regeneration of such tissue is to be avoided. The benefits to be derived from the knowledge of the absence of any ovarian tissue whatever are great from a symptomatic point of view, because their symptoms cannot then exist. Blood vessels correspond to the spermatic arteries of the male, springing from the anterior aspect of the aorta below the level of origin of the renal vessels, each gaining the pelvis in the fold of the peritoneum forming the suspensory ligament of the ovary, and enters the ovary at its anterior border. These arteries anastomose freely near the hilum with vessels derived from the uterine arteries. Page One Hundred Thirteen The blood is returned by communicating veins similar to the pampiniform plexus in the male. Nerves are from a plexus which accompanies the ovarian artery and which is con- tinuous above with the renal plexus. Other fibers are derived from the lower part of the aortic plexus and join the plexus on the ovarian artery. The afferent impulsfe from the ovary reach the central nervous system through the posterior root fibers of the tenth thoracic nerve. Ovarian lymphatics form a dense plexus, which when infected overshadows the sub- jacent venous plexus. After the plexus becomes smaller, four to six collecting trunks are formed. They take an upward course with the ovarian vessels, pass anteriorly to the common iliac vessels and ureter accompanying and then anastomose with lymphatics from the Fallopian tube and uterine fundus at the fifth lumbar vertebra, after which they terminate in the lateral aortic glands. One vessel passes downward and slightly outward into the superior part of the ligament and terminates in one gland of the middle chain of the internal iliac group. Marcille, Zeissl and Horowitz have one of the testicular lym- phatics end in the same gland of the abdomino-aortic group. ETIOLOGY. Anomalies, Diseases and Injuries. Anomalies, Diseases | ^f^"- ^ [ Malignant. Injuries. ANOMALIES. Anomalies may be congenital or acquired, primary or secondary, single or multiple, in form, size, shape and position. When single they are invariably of horse-shoe shape. DISEASES. Benign. Malignant. BENIGN. Fibromata may be congenital or acquired, primary or secondary, single or multiple, vary in size, shape and location. Papillomala may be congenital or acquired, primary or secondary, single or mul- tiple, vary in size, shape and location, with or without pedicles and disappear spontaneously, though this is a rare occurrence. Adenomata may be congenital or acquired, primary or secondary, vary in size, shape, number cind location, with or without pedicles, usually without, and seldom disappear spontaneously. Pregnancies of the ovaries are of rare occurrence, with considerable doubt as to the possibility of multiple ovarian pregnancies. They may mature without rupture, become encysted and remain indefinitely, or rupture at any period during development into the peritoneal or intestinal cavity, bladder, uterus, rectum or vagina. Adhesions may be congenital or acquired, primary or secondary, single or multiple, with or without disease, to the uterus, Fallopian tubes, bladder, intestines, appendix, rectal or vaginal wall. C'^sts may be congenital or acquired, primary or secondary, acute or chronic, single or multiple, contain blood, pus, serum, echinococci, fecal, colloid or dermoid material. Page One Hundred Fourteen rupture into the peritoneal cavity, Fallopian tube, uterus, bladder, intestinal tract, rectum or vagina. Hernia of the ovaries may be congenital or acquired, primary or secondary, uni- lateral or bilateral, through the femoral or inguinal ring, into the labia, bladder, rectum or vagina. Fisiulce may be congenital or acquired, primary or secondary, acute or chronic, single or multiple, open into the peritoneal cavity. Fallopian tube, uterus, bladder, intestinal canal, rectum, vagina or perineum. MALIGNANT. Carc'inomata may be primary or secondary, usually primary, involving one or both ovaries, rarely both, in any portion of the gland and extend into the surrounding structures. Sarcomala may be primary or secondary, usually primary, involve one or both ovaries and extend into the ovarian ligament first, broad ligament tube, uterus and sur- rounding soft structures like carcinoma. INJORIES. Ruptures, incisions, punctures and lacerations may be by accident or design, primary or secondary, single or multiple, penetrating or non-penetrating, in any portion of the ovary, extend into the peritoneal cavity. Fallopian tube, uterus, bladder, vagina, rectum, peri- neum, appendix, intestinal canal or externally into the soft structures or through the skin, anywhere about the pelvis. SYMPTOMS. Symptoms such as obtain with ovaries even when aggravated by profound pathology are very indefinite. This is especially so with the earlier manifestations, which are so often slight in character, and because the nerve fibers are from the same source and intimately associated. Pain having its origin in one would be reflected to the other and thus involve the uterus and surrounding structures which are also dominated by branches of the pudic. This being so, primary pain of one structure would become secondary with others, especially the Fallopian tubes and uterus. Local disturbances in the ovaries are in the form of pain and tenderness, sometimes induced by the sense of touch. Like their analogue the testicles, they are more sensitive than any other tissue in the uro-genital tract, and their sensitiveness increases with pathology. Their irregularities, therefore, are more readily reckoned with and defined, especially when general disturbances are manifested. Pressure upon a normal ovary will Induce tenderness, pain, chill, headache, shock, nausea and vomiting. It is therefore apparent why they are so greatly influenced by pathology within them or their adjacent structures or those far distant within the pelvis or perineum, that possess the same nerve supply. The very great variety of conditions to which the ovaries are subjected, produce symptoms Identical in character thus rendering It impossible to identify any one of them. Page One Hundred Fifteen CHAPTER XXIV. FALLOPIAN TUBES. ANATOMY. fig,. 56. — Fallopian tube and blood vessels (Kelley). ALLOPIAN TUBES are composed of the muscular, mucous and submucous coats, lined with epithelium and covered with peri- toneum. The circular muscle fibers are more numerous near the uterus. The mucous coat is covered with ciliated epithelium, arranged for driving the contents of the tube toward the uterus with which the epithelium is continuous, and extends to the fim- briated end of the tubes where they join the peritoneum. Blood vessels are from the uterine artery and branches of the ovarian artery and the veins connect with the uterine and ovarian veins. Nerves are derived from the plexus that supplies the ovary and that which connects with the uterus. Afferent fibers appear to belong to the eleventh and twelfth thoracic and the first lumbar nerves. The lymphatics join the lumbar group of glands. ETIOLOGY. Ai Diseases and Injuries. Anomalies. Benign. Malignant. Injuries. D { Page One Hundred Sixteen ANOMALIES. Anomalies may be congenital or acquired, primary or secondary, single or multiple, in form, size, length, relation to other structures, entrance into the uterus, blood, nerve and lymph supplies, or one or both entirely absent or imperforate. DISEASES. Benign. Malignant. BENIGN. Inflammation may be primary or secondary, acute or chronic, local or general, mild or severe. Tuberculosis may be primary or secondary, local or general, single or multiple, acute or chronic, in any of the tissues or portion of the tube, become arrested, disappear or con- tinue to destruction. Syphilis may be congenital or acquired, primary or secondary, single or multiple, local or general, arrested, disappear spontaneously or continue in its destruction. Papillomala may be congenital or acquired, primary or secondary, single or mul- tiple, with or without pedicle, in any portion of the tube, remain quiescent, disapp>ear or continue to grow. Adenomata may be congenital or acquired, primary or secondary, single or multiple, usually without pedicle, in any portion of the tube, remain quiescent, continue to grow, or disappear spontaneously, though this seldom occurs. Fibromata may be congenital or acquired, primary or secondary, single or multiple, vary in size, shape and location, continue to grow, remain quiescent or disappear spon- taneously. Pregnancies may be primary or secondary, single or multiple, in any portion of the tube, develop to about the sixth week before which time they invariably rupture to escape into the peritoneal cavity, broad ligament, uterus, bladder, intestinal canal, rectum, or vagina, become encysted in the broad ligament where they may die and remain indefinitely or develop to maturity, and then die, and remain indefinitely. Cysts may be congenital or acquired, primary or secondary, single or multiple, acute or chronic, vary in size, contain blood, pus, serum, echinococci, colloid or dermoid ma- terial, rupture into the broad ligament, peritoneal cavity, uterus, bladder, rectum, vagina, perineum, intestinal tract or soft tissues, through the cutaneous structures anywhere about the pelvis. Fislulcs may be congenital or acquired, primary or secondary, single or multiple, open into the uterus, peritoneal cavity, bladder, vagina, rectum, perineum or through the ex- ternal soft structures. Prolapse may be congenital or acquired, primary or secondary, single or multiple, behind the uterus, into the vaginal vault, with other tissues, or complicated with various inguinal, femoral and ventral herniae the same as ovaries. MALIGNANT. Carcinomata may be primary or secondary, usually primary, in any portion of the tube, unilateral or bilateral, and extend into the broad ligament, uterus, or ovaries. Sarcomata may be primary or secondary, usually primary, single or multiple in any portion of the tube, unilateral or bilateral, usually unilateral. Page One Hundred Seventeen INJURIES. Incisions, punctures, ruptures may be primary or secondary, single or multiple, vary in size and location, by accident or design, complete or incomplete, extend into th»v peri- toneal cavity, uterus, bladder, rectum, vagina, or the overlying soft structures. Foreign bodies, though small, may enter the Fallopian tube through the uterine canal, the w^all of the tube by v^^ay of the peritoneal cavity, the rectum, vagina, or through the overlying soft structures. SYMPTOMS. Sy^mptoms due to Fallopian tube disturbances are very similar in character to those of the ovaries and uterus because of their close proximity and intimate relation of nerves. Their similarity is so great that instances are few where they can be defined, the element of doubt always existing. Local tenderness and pain are the earlier manifestations and while they may grad- ually increase in severity until the general manifestations assert themselves they are not definite. Symptoms are alike with all conditions of the tubes and their adjacent structures and for this reason cannot be made specific, nor can they be differentiated from conditions in their adjacent structures except in a few instances when their symptoms predommate Page One Hundred Eighteen CHAPTER XXV. RECTUM ANATOMY. Fig. 57. — Pelvic organs seen in dissection of male perineum (Deaver). HE RECTUM is seven inches long and extends from the sigmoid to the external sphincter ani, and its first portion ending in front of the tip of the coccyx and bending somewhat backward. In front of the upper portion of the rectum are the perineum, blad- der, seminal vesicles, vasa deferentia emd prostate in the male and vagina in the female. The second portion extends from the tip of the coccyx and is almost entirely encircled by the internal sphincter am muscle, and not covered with peritoneum. The distance from the interna] sphincter to the meso-sigmoid is four inches. The cylinder in the upper portion though about two inches in diameter may be distended to four or five inches with feces or the hand without rupture. External sphincter ani muscle arises from the coccyx and extends to the anus, sometimes to the bulbocavernosi muscle. It Page One Hundred Nineteen is composed of striated fibers which lie directly beneath the skin and its purpose is to open and close the anal orifice and to fix the anterior tendon of the perineum during contraction of the bulbocavernosi, some fibers completely surrounding the anus. In the female a few decussate with those of the sphincter vaginae and nearer the outside circles than the internal sphincter. The anterior fibers pass along the sides of the prostate and vagina. The middle fibers blend with the longitudinal fibers of the rectum and extend to the sphincter ani and the posterior fibers join the other lavatori to become inserted at the tip of the coccyx. Blood supply is the superficial perineal artery which is a branch of the internal pudic, given off just before it enters the space between the layers of the triangular ligament of the perineum. It is sometimes termed the transverse artery of the perineum. The fourth sacral and inferior hemorrhoidal nerves supply the external sphincter ani muscle. Some fibers coming from the pudic and inferior mesenteric and pelvic plexuses, arise from the fourth sacral and inferior hemorrhoidal branch of the pudic and they in turn connect with the small sciatic, pudic and fourth sacral nerves. The inferior hemorrhoidal nerve usually branches off the pudic after it peisses through the lesser sacro-sciatic foramen and supplies the external sphincter, cutaneous filaments to the perineal integument and communicating branches of the inferior pudendal and super- ficial nerves. It is thus seen that it has three important branches, the inferior hemorrhoidal, perineal and dorsal nerve of the penis and clitoris, the main trunk having passed forward in Al- cock's canal in the obturator fascia. With the change from cloacal to the true mammalian condition, the pudic trunk was necessarily split into many twigs, it no longer answering the purpose for which it was first intended. Levator ani muscle is composed of three sets of fibers. Anterior, pass along the side of the prostate and vagina. Middle, blend with the longitudinal fibers of the rectum and extends to the sphincter ani. Posterior, join the other levator ani to be inserted into the tip of the coccyx. The entire muscle is supplied by the inferior hemorrhoidal and fourth and fifth sacral nerve, and its function is to raise the pelvic floor and fascia. Blood Supply. The levator ani, obturator internus, pyriformis and coccygeus mus- cles are in part supplied by the gluteal. The pyriformis and coccygeus also receive tranches from the lateral sacral artery. The sciatic artery also sends branches to the pyriformis, levator ani and coccygeus muscles, and the obturator receives a branch from the internal pudic artery. The recto vesical fascia's principal function is to prevent pus and extravasated urine from passing from the perineum to the pelvis. Blood supply of the rectum is from three hemorrhoidal and middle sacral arteries, the m.ost important of which is the superior hemorrhoidal, which is the prolongation of the inferior messenteric trunk, which after reaching the rectum from the meso-colonic root, divides into two chief branches which course around the sides of the rectum anteriorly. Many of its small branches then perforate the rectal muscular fibers to supply their mucous membrane. The superior and middle hemorrhoidal anastomose both externally and internally to the rectal wall. The inferior hemorrhoidal artery pierces the inner wall of Alcock's canal, and runs obliquely forward and inwards. It soon divides into two or three main branches, which sometimes arise separately and pass across the space to the anal passage. The artery anastomoses in the walls of the anal passage with its fellow on the opposite side and with the middle and superior hemorrhoidal arteries. It also anastomoses with the transverse perineal arteries and supplies cutaneous twigs to the region of the anus, and others turn around the border of the gluteus maxims to supply the lower part of the buttock. Nerve supply is from the sympathetic twigs which are derived from the inferior mes- senteric and hypogastric (sometimes called pelvic plexus) and cerebrospinal system, fibers of which arise from the second, third and fourth sacral nerves. Fibers of the inferior hemorrhoidal branch of the internal pudic nerve (third and fourth sacral) are also dis- Page One Hundred Twenty tributed to the lower part of the anal canal and external sphincter. The second, third and fourth sacral nerves convey motor impulses to the longitudinal fibers but also inhibits im- pulses to the circular muscular fibers. Fibers from the sympathetic also convey motor impulses to the circular muscle and inhibitory fibers to the longitudinal muscles of the rectum. The reflex center which governs the action of the sphincter and the muscular fibers of the rectum (defecation center) is situated m the lumbar region of the cord and appears to be capable of carrying out the whole act of defecation even when separated from the brain. Lymphatics of the rectum pass to the glands on the front of the sacrum and some in the lower portion of the anal canal join the lymphatics around the anus and pass with them to the oblique set of the superficial inguinal glands, a few from the lower portion of the rectum are said (Quenu) to jom the iliac glands but these are not constant according to Gerota. ETIOLOGY. Anomalies, Diseases and Injuries. Anomalies. Dr Benign, iseases - i\ ^r i • ( Malignant. Injuries. ANOMALIES. Anomalies may be congenital or acquired, primary or secondary, single or multiple, in any portion, vary in length, diameter and uniformity of lumen, position and relation to other structures, a part or all of the rectum absent, and the anal opening behind, in the vagina, bladder, urethra, uterus, peritoneal cavity or absent. DISEASES. Benign. Malignant. BENIGN. Benign diseases are of many kinds and varieties and may occupy any portion of the cylinder. They may be congenital or acquired and vary in size and rate of growth. Proctitis may be primary or secondary, acute or chronic, local or general, mild or severe. Ulcers may be congenital or acquired, primary or secondary, acute or chronic, single or multiple, result from infection or pressure, necrosis, extend partially or completely through any portion of the rectal wall especially in the lower third of the cylinder. Fissures may be congenital or acquired, primary or secondary, acute or chronic, sin- gle or multiple, vary in depth, length and width in one or all of the tissues of the wall, location, almost invariably external or between the sphincters. Their most frequent cause is the passage of such a mass through one of normal tension, or the presence of cicatricial tissue. Fistulce may be congenital or acquired, primary or secondary, acute or chronic, single or multiple, extend into and through the perineum, posterior soft structures, urethra, blad- der, prostate, vagina, uterus, or peritoneal cavity, vary in size, length and location, straight or tortuous. Page One Huiulivil T\vent\-One Varicosities such as hemorrhoids, angiomata and aneurysms may be congenital or ac- quired, primary or secondary, acute or chronic, in one or more vessels or any portion of the rectum, vary in size and sometimes disappear spontaneously. ^ Papillomata are of the more common varieties found within the rectum and they may be congenital or acquired, primary or secondary, single or multiple, usually multiple, located anywhere upon the mucous membrane and develop to a considerable size, usually with pedicle. (See Papillomata and Adenomata of the Rectum, A^. Y. Med. Jour., Vol. LXXX, 1907, also Papillomata and Adenomata, Hist. Review, Amer. Jour. OF Dermatology, March 1, 1908. (Ricketts.) Adenomata may be congenital or acquired, primary or secondary, single or multiple, upon any portion of the inner surface of the rectum, vary in size and shape, remain quies- cent, continue to grow or disappear spontaneously. They usually have a broad base and appear most frequently in the lower half of the cylinder. Tuberculosis may be primary or secondary, acute or chronic, single or multiple, vary in size, be upon any portion and in any tissue, but usually in the lower third of the cylinder and extend into the surrounding tissues. Syphilis may be congenital or acquired, primary or secondary, acute or chronic, single or multiple, vary in size, in amy tissue or location and usually in the lower third of the cylinder, sometimes disappears spontaneously or cause total destruction of any part or all of the rectal wall in the form of gumma. Fibromata may be congenital or acquired, primary or secondary, single or multiple, vary in size, shape, location, in any tissue, usually in the lower half of the cylinder. Lipomata may be congenital or acquired, primary or secondary, single or multiple, vary in size, shape, location, in any tissue but usually about the middle of the cylinder. Prolapsus may be congenital or acquired, primary or secondary, acute or chronic, one of four degrees. Hyperexertion to stool when the lumen of the rectum has been lessened by any cause and when the sphincters have relaxed unduly are the most common causes. Infection may be primary or secondary, bacterial or parasitic, local or general, mild or severe, acute or chronic, and result in abscess within the rectal wall or any of the adjacent tissues or organs. Cyds may be congenital or acquired, primary or secondary, acute or chronic, single or multiple, in any portion or tissue, contain blood, pus, serum, echinococci or dermoid ma- terial, rupture posteriorly through the soft structures, into the vagina, rectum, perineum, urethra, uterus or peritoneal cavity. Strictures may be congenital or acquired, primary or secondary, acute or chronic, partial or complete, single or multiple, in any portion of the rectal wall. Parasites may be congenital or acquired, primary or secondary, single or multiple, re- main indefinitely with or without producing inflammation, encysted or within the open cavity. Foreign bodies may enter from without or within, through the anus or mouth, vagina, bladder, uterus, peritoneal cavity or external soft structures. Feces may be hard or soft in consistency and either form cause great rectal or con- stitutional disturbances. If the normal diameter of a mass normal in consistency, is less- ened from any cause at a given point distant to the sphincters, the pressure upon them will not be normal in uniformity or degree because the line of perpendicular will have been changed. Thin or watery stools are probably exceptions to this rule and an empty gut significant of quietude. These remarks apply to both sexes but because of the difference in. their anatomical relations the same rules for classification do not obtain. In the male the fecal mass is pushed forward against the prostate, seminal ducts and urethra while in the female this force is forward against the vaginal wall and uterus. MALIGNANT. Malignant diseases are of two kinds with their respective variations. Those sar- comatous in character are less frequent and usually of secondary origin. The carcinomata are more common eind as a rule primary in origin. Either variety may occur upon any Page One Hundred Twenty-Two portion of the rectal wall or mucous membrane, always smgle and more frequent m the lower half of the rectum and more often in the male in whom ulcer is more common. Carcinomala may be primary or secondary, single or multiple, in any tissue or portion of the rectum, usually single, and appear most frequently on the mucous membrane imme- diately overlying the tip of the coccyx. Sarcomata may be primary or secondary, single or multiple, usually single, in any tissue or portion of the rectal wall. INJURIES. Ruptures. Laceration. Incision. Puncture. Rupture of the rectum may assume one of three varieties, laceration, incision and puncture and each vary in extent, number and position, partial or complete, through the rectal wall or when complete, extend into the surrounding soft structures, vagina, uterus, bladder, peritoneal cavity, urethra, seminal vesicles or prostate. SYMPTOMS. Rectal Reflexes and Neuroses. (By H. C. Von Dahm, M. D.) The consideration of rectal reflexes and neuroses leads to anatomical fields sometimes far removed from the rectum, and again to fields so intimately associated with that organ, not only anatomically, but from symptomatic and pathologic standpoints, that the subject becomes a vast one and of no little importance. The close association of the rectum with the genito-urmary system makes the success- ful study of either one necessarily lead to a consideration of the other. Especially is this true as to the neurotic manifestations of their pathology. A review of the nerve supply of the rectum shows its innervation derived from both the sympathetic and spinal systems with a predomination of the sympathetic. This system supplies numerous filaments from the hypogastric, sacral and mesenteric plexes, while the spinal element is derived from the third, fourth and fifth sacral nerves. In their distribution the two nerve elements become intimately interwoven. The spinal nerves in their course to the rectum, pass through the sacral plexus of the sympathetic and are dis- tributed to the striated muscles, the levator ani and external sphincter, thence to the peri- neal skin and the modified epithelium of the anorectal region as far up as the anorectal line. Above this line we find only sympathetic distribution, the voluntary control of the rectal function ceases and becomes an automatic one, entirely under the control of the sympathetic. The perineum, prostate, urethra, bladder and vagina receive a great part of their spinal and sympathetic nerve supply from the same source as the rectum and anus, \\'hich fact accounts for the various reflexes between the rectal and genito-urinary systems. Any pathological condition of the rectum may give rise to genito-urinary symptoms, while many times genito-urinary lesions have their symptoms referred to the rectum. This rule obtains with both sexes though more frequently and numerous in the male and of a more severe and complicated character because the genito-urinary system of the female is less complicated in its arrangement. Rectal disturbances are factors that always necessitate consideration, especially when the male reproduction organs are disturbed. They are so intimately associated and com- plex, that it is often impossible to discover their cause or origin, but such a difficulty is not so likely to be encountered when the rectum in the female is primaiily disturbed, because for want of so close a proximity of the two tracts as exists in the male. The same might he said about the urinary apparatus in the female because of the absence of complexity. While symptoms of rectal conditions are quite significant, those of the sigmoid are intimately associated because their distinction is but imaginary, one being an extension of the other. Page One Huiulred Twenty-Throe From the studies of various investigators and anatomists, we draw the conclusion (a) that the innervation of the pelvic viscera is derived chiefly from the sympathetic or is greatly controlled by it.