" T^C TL.^ F L^ /d&3 Ctriuntbta (Mntttewttp College of ^fipfi^ictanig anb burgeons; Hihxavp A MANUAL OP Auscultation and Percussion; EMBRACING THE PHYSICAL DIAGNOSIS OF DISEASES OF THE LUNGS AND HEART, AND OF THORACIC ANEURISM. BY AUSTIN FLINT, M.D., PROFESSOR OF THE PRI^X•IPLES AND PRACTICE OF MEDICINE AND OF CLINICAL MEDICINE IN THE BELLEYUE HOSPITAL MEDICAL COLLEGE, ETC., ETC. THIRD EDITION, REVISED. PHILADELPHIA: HENRY C. LEA^S SON & CO. 1883. Entered, according to Act of Congress, in the year 1880, by HENRY C. LEA, In the office of the Librarian of Congress. All rights reserved. SHKUMAN & CO., riMNTERS. PREFACE TO THE THIRD EDITION. In the revision of this manual for a third edition, it has been deemed advisable, as in the previous editions, to restrict its scope to auscultation and percussion con- sidered chiefly with reference to their practical applica- tion, and to present these with as much condensation as possible. In the present edition, the modes by which pulmonary signs may be reproduced in the lungs re- moved from the body, and by artificial illustrations, have been briefly stated. The author has also intro- duced some practical points kindly suggested by his friend and colleague, Professor Janeway. The speedy exhaustion of the second edition may, perhaps, be fairly regarded as evidence, not alone of the usefulness of the work to the medical student and practitioner, but of an increasing appreciation of the importance of the study of auscultation and percussion, as well as of the analytical method by which the study is facilitated, and knowledge of the physical signs made readily available in diag- nosis. New York, March, 1883. PREFACE TO THE SECOND EDITION. This work contains the substance of the lessons which the author has for many years given, in connection with practical instruction in auscultation and percussion, to private classes composed of medical students and prac- titioners. In his courses of practical instruction his plan has been, 1st. To simplify the subject as much as possible, avoiding all needless refinements ; 2d. To consider the distinctive characters of the different physical signs as determined, not by analogies, nor by deductions from physics, but by analysis, and as based especially on variations in the intensity, pitch, and quality of sounds ; 3d. To impress the fact that the significance of physical signs relates to certain physical conditions, and the im- portance of a familiar acquaintance with these conditions, as well as with the distinctive characters of the signs by which they are represented ; 4th. To enforce the neces- sity of sufficient study of the physical conditions and the signs of health, as a sine qua non for success in the study of the physical diagnosis of diseases; and, 5th. To waive discussion of the mechanism of signs, when- Vlll PREFACE TO THE SECOND EDITION. ever this is open for discussion, taking the ground that our knowledge of the significance of signs rests solely on the constancy of their connection with the physical con- ditions which they represent. This plan, of which the utility has been confirmed by continued experience, has been followed throughout the present volume, and the favor with which the work has been received has seemed to show that no radical changes were required. In revising it for a second edition, there- fore, the author has confined himself to such additions as seemed likely to render it more useful not only to stu- dents engaged in the practical study of the subject, but also to practitioners as a hand-book for ready reference. New York, January, 1880. CONTENTS. CHAPTER 1. INTRODUCTION. PAGE Definition of percussion and auscultation — The sounds obtained by these methods representing healthy and morbid physical con- ditions — Definition of signs— The basis of our knowledge of signs the constancy of association of certain sounds with certain physical conditions in health and disease — The present state of perfection of our knowledge of signs furnished l)y auscultation and percussion — Requirements for the successful study of these methods of exploration — The anatomy and physiology of the chest — An enumeration of the points relating thereto which are of especial importance — The physical conditions incident to the different diseases of the chest ; the conditions relating to the res- piratory system stated, and a summary of them — The distinctive charactersof healthy and morbid signs ; variations in intensity, pitch, and quality, considered as the chief source of the char- acters distinguishing the signs of disease from each other and from those of health — Other distinctions than those of intensity, pitch, and quality — The analytical method of the study of aus- cultation and percussion — The significance of the signs as re- gards the physical conditions which they severally represent — " Morbid conditions, not individual diseases, represented by the morbid signs — Regional divisions of the chest — Anatomical re- lations of the regions severally to the parts within the chest, . 13 CHAPTER II. PERCUSSION IN HEALTH. Percussion with the fingers or with a percussor and pleximeter — The normal vesicular resonance on jiercussion ; its distinctive characters relating to intensity', pitch, and quality — Variations in the characters of the normal vesicular resonance in different CONTENTS. PACE persons — Relation of the pitch of resonance to the vesicular quality — Tympanitic resonance over the abdomen — Variations of the normal resonance in the diflferent regions of the chest — Enumeration of the regions in which the resonance on the two sides varies, and those in which it is identical in health — Influence of age on the normal resonance — Influence of the acts of respiration on the resonance — Eules in the practice of percussion, 38 CHAPTER III. PERCUSSIOX IN DISEASE. Enumeration of the signs of disease furnished by percussion — Re- quirements for practical knowledge of these signs — The dis- tinctive characters of, the morbid physical conditions repre- sented by, and the difierent diseases into the diagnosis of which enter, these signs, severally, to wit, 1. Absence of resonance or flatness ; 2. Diminished resonance or dulness ; 3. Tympanitic resonance ; 4. Vesiculo-tympanitic resonance ; 5. Amphoric re- sonance; 6. Cracked-metal resonance — Sense of resistance felt in the practice of percussion, as a morbid sign, .... 54 CHAPTEE IV. AUSCULTATION IN HEALTH. Importance of the study of the auscultatory sounds in health — Immediate and mediate auscultation — Advantages of the bin- aural stethoscope — Rules to be observed in auscultation — Di- visions of the study of auscultation in health — The normal laryngeal and tracheal respiration — The normal vesicular mur- mur ; its distinctive characters, and the variations in the differ- ent regions on the same side, and in corresponding regions on the two sides of the chest — The normal vocal resonance — The laryngeal and tracheal voice and whisper — The normal thoracic vocal resonance and fremitus ; the distinctive characters of each ; the variations in difierent regions on the same side, and in corresponding regions on the two sides of the chest — The normal bronchial whisper, with its variations in different re- gions on the same side, and in corresponding regions on the two sides of the chest, 65 CONTENTS. Xi CHAPTEK V. AUSCULTATION IN DISEASE. PAGE The respiratory signs of disease: — Abnormal modifications of the normal respiratory sounds: — Increased vesicular murmur — Diminished vesicular murmur — Suppressed respiratory sound — Bronchial or tubular respiration — Broncho-vesicular respira- tion — Cavernous respiration — Broncho-cavernous respiration — Vesiculo-cavernous respiration — Amphoric resinration — Short- ened inspiration — Prolonged expiration — Interrupted respira- tion. Adventitious respiratory sounds or rales : — Laryngeal and tracheal rales. Moist bronchial rales, coarse, fine, and subcrepi- tant — Vesicular or crepitant rale — Cavernous or gurgling rale — Pleural friction rales, metallic tinkling and splashing. In- determinate rales — The vocal signs of disease : — Bronchophony — Whispering bronchophony — ^gopbony — Increased vocal re- sonance — Increased bronchial whisper — Cavernous whisper — Pectoriloquy — Amphoric voice or echo — Diminished and sup- pressed vocal resonance — Diminished and suppressed vocal fre- mitus — Metallic tinkling. Signs obtained by acts of coughing or tussive signs, 85 CHAPTEK VI. THE PHYSICAL DIAGNOSIS OF DISEASES OF THE RESPIRATORY ORGANS. Affections of the larynx and trachea — Bronchitis seated in large bronchial tubes — Bronchitis seated in small bronchial tubes, or capillary bronchitis — Collapse of pulmonary lobules — Lobular pneumonia — Asthma — Pulmonary or vesicular emphysema — Pleurisy, acute and chronic— Empyema — liydrothorax — Pneu- mothorax — Pneumo-hydrothorax — Pneumo-pyothorax — Acute lobar pneumonia — Circumscribed pneumonia — Embolic pneu- monia — Hsemorrhagic infarctus — Pulmonary apoplexy — Pul- monary gangrene — Pulmonary oedema — Carcinoma of lung — Tumor within the chest — Acute miliary tuberculosis — Pulmo- nary phthisis — Fibroid phthisis, interstitial pneumonia, or cir- rhosis of lung — Diaphragmatic hernia, 136 Xll CONTENTS. CHAPTEE YII. THE PHYSICAL CONDITIOKS OF THE HEART IN HEALTH AND DISEASE. THE HEART-SOUNDS AND CARDIAC MURMURS. PAGE Physical conditions of the heart in health : — Boundaries of the prsBcordia — Normal situation of the apex-beat — Boundaries of the deep and of the superficial cardiac space — Relations of the aorta and the pulmonary artery to the walls of the chest — The heart-sounds — Characters distinguishing the first and the second sound — Mechanism of the production of the heart-sounds — Aus- cultation of the pulmonic and the aortic second sound separately — Movements of the auricles and ventricles in relation to each other. Physical conditions of the heart in disease : — Enlarge- ment of the heart — Hypertrophy and dilatation — Abnormal im- pulses of the heart, and modifications of the apex-beat — Valvu- lar lesions — Roughness of the pericardial surfaces — Liquid with in the pericardial sac — Abnormal modifications of the heart- sounds — Reduplication of heart-souuds — Cardiac murmurs — Normal and abnormal blood-currents within the heart, and their relations with the heart-sounds — Mitral direct murmur — Mitral regurgitant murmur — Mitral systolic non-regurgitant, or intra-ventricular murmur — Aortic direct murmur — Aortic regurgitant murmur, and an aortic diastolic non-regurgitant murmur — Coexisting endocardial murmurs — Tricuspid direct murmur — Tricuspid regurgitant murmur^Pulmonic direct murmur — Pulmonic regurgitant murmur — Facts of practical importance in relation to endocardial murmurs — Pericardial . or friction murmur, 181 CHAPTEE VIII. THE PHYSICAL DIAGNOSIS OF DISEASES OF THE HEART AND OF THORACIC ANEURISM. U Enlargement of the heart by hypertrophy and dilatation — Val- vular lesions, mitral, aortic, tricuspid, and pulmonic — Fatty degeneration and softening of the heart— Endocarditis — Peri- carditis — Functional disorders— Thoracic aneurism, . . 217 MANUAL OF AUSCULTATION AND PERCUSSION. CHAPTER I. INTRODUCTION. Definition of percnssion and auscultation — The sounds obtained by these methods representing healtliy and morbid physical conditions — Definition of signs — The basis of our knowledge of signs the con- stancy of association of certain sounds with certain physical condi- tions in health and disease — The present state of perfection of our knowledge of signs furnished by auscultation and percussion — Ee- quirements for the successful study of these methods of exploration — The anatomy and physiology of the chest — An enumeration of the points relating thereto which are of especial importance — The phys- ical conditions incident to the difl'erent diseases of the chest : the conditions relating to the respiratory system stated, and a summary of them — The distinctive characters of healthy and morbid signs; variations in intensity, pitch, and quality, considered as the chief source of the character distinguishing the signs of disease from each other and from those of health — Other distinctions than those of intensity, pitch, and quality — The analytical method of the study of auscultation and j)ercussion — The significance of signs as regards the physical conditions which they severally represent — Morbid con- ditions, not individual diseases, represented by the morbid signs — Eegional divisions of the chest — Anatomical relations of the regions severally to the parts within the chest. Physical Exploration. The physical exploration of the chest embraces six different methods, namely : auscultation, percussion, in- spection, palpation, mensuration, and succussion. Of these, auscultation and percussion, dealing with sounds, involve the sense of hearing. In percussion, the sounds 14 INTRODUCTION. are produced by striking upon the walls of the chest ; in auscultation, they are caused by acts of breathing, speak- ing, and coughing. The sounds in auscultation and percussion are, 1st, normal or healthy sounds, being produced when there is no disease of the chest; and, 2d, abnormal or morbid sounds, being produced when the chest is the seat of dis- ease. The sounds, healthy and morbid, constitute what are known as physical signs. Frequently, for the sake of brevity, the terms signs, without the word physical, is used to denote these sounds. Conventionally, physical signs, or signs, are terms employed in a sense of contra- distinction from the term symptoms. The signs are dis- tinguished, of course, as normal or healthy, and abnormal or morbid. The sounds which constitute signs represent certain physical conditions pertaining to the chest. The normal or healthy signs represent physical conditions existing when the organs are not affected by disease; the abnormal or morbid signs represent physical conditions which are deviations from those of health, being incident to the various diseases of the chest. The physical conditions represented by signs may be distinguished as normal or healthy, and abnormal or morbid conditions. The representation of healthy and morbid physical conditions by certain healthy and morbid signs is estab- lished by having ascertained a constancy of association of the siffus with the conditions. This constancv of as- sociation is ascertained by observation or experience. The sounds which are constantly obtained by percussion and auscultation in health are thereby establislied signs of healthy conditions, and the sounds which are only obtained in cases of disease are therebv established siffus PHYSICAL EXPLORATION. 15 of m()rl)i(l conditions. Our knowledge of certain sounds as the signs of certain physical conditions can have no reliable basis other than the constancy of the connection of the former with the latter. This constancy of connec- tion is determined by the study of the sounds during life and examination of the organs after death. The exist- ence of certain conditions is not to be inferred from the characters of certain sounds until the connection of the sounds with the conditions has been ascertained by ex- perience ; then, and then only, are the sounds to be reckoned as signs of these conditions. So, also, it is not to be inferred from certain physical conditions found after death, that certain sounds must have been produced during life, until the connection between the conditions a!id the sounds has been ascertained by experience. In other words, our knowledge of signs as representing physical conditions, can rest on no other than a purely empirical foundation. Our knowledge of the signs representing the physical conditions in healtli and disease, thanks to the labors of Laennec and of those who have followed in his footsteps, has been brought to great perfection. The practical ob- ject of this knowledge is to determine by means of aus- cultation and percussion, together with the other methods of exploration, the existence of either healthy or morbid physical conditions, and to discriminate the latter from each other; that is to say, the practical object is diag- nosis. The signs now known to represent physical con- ditions, healthy and morbid, taken in connection with symptoms and pathological laws, render, for the most part, the diagnosis of diseases of the chest easy and positive. Hence, it becomes the duty of the medical student and practitioner to give to auscultation and per- 16 INTRODUCTION. cussion attention sufficient, at least, for their practical application to the diagnosis of the diseases commonly met with in medical practice ; and this duty is the more imperative because it involves neither peculiar difficul- ties nor great labor. In entering upon the undertaking it is important to consider the requirements for the suc- cessful study of this })rovince of practical medicine. These requirements relate to : 1st,, the anatomy and physiology of the chest; 2d, the morbid physical condi- tions incident to the different diseases of the chest; 3d, the distinctive character of healthy and morbid signs, and 4th, the signiticance of the signs as regards the physical conditions whicii they severally represent. Anatomy and Physiology of the Respiratory Organs. The necessity of a certain amount of knowledge of the anatomy and physiology of the chest, as a requirement for the study of auscultation and percussion, together with the other methods of physical exploration, is too obvious to need any discussion. The physical condi- tions of health must be known as preparatory for aj)pre- ciating the piiysical conditions of disease. It would be absurd to think of studying the latter until the former are known. The student, therefore, who is not acquainted with the anatomy and physiology of the chest, must defer entering upon the study of physical diagnosis until this requirement is fulfilled. Familiarity with the morbid physical conditions is necessary ; and for the advanced medical student or the practitioner, it is advisable to re- fresh the memory with a reviewal of certain anatomical and physiological points before beginning the study of auscultiition and percussion. These points, relating es- pecially to the physical conditions of health, cannot be ANATOMY AND PHYSIOLOGY OF GUEST. 17 considered in this work. A simple enumeration of thcni can only be introduced, the reader being referred for details to treatises on anatomy and physiology. Important anatomical conditions relate to the bones of the chest, namely, the general conformation of the thorax; the differences in respect of the obliquity of the ribs, from above downward ; the direction of the costal cartilages, the connection with the sternum, and the angles formed by the junction of the ribs and cartilages; the differences in width of the intercostal spaces in the upper, middle, and lower portions of the anterior, lateral and posterior aspects of the thorax, together with the re- lations of the scalpula and clavicle. The relative thick- ness of the muscular covering of the chest in different situations is to be considered, and, in women, the varying size of the mammce. The attachments of the diaphragm to the thoracic walls, and its relations to the organs be- low, as well as above it, are points of importance. Important physiological conditions relate to the parts -which the ribs, costal cartilages, sternum and diaphragm severally play in the movements of respiration. The differences, in respect of these movements, in tranquil and in forced breathing ; the contrast between the two sexes, and between early and advanced life are points to be studied. Other points are, the frequency of the respirations in health, and the relative duration, rapidity, and force of the respiratory and the expiratory move- ments. Certain anatomical and physiological points pertain to the organs within the chest. The more important of these, relating to normal physical conditions, are the fol- lowing : 1st, as regards the lungs, the connections of the pleura, and the smoothness of the pleural surfaces in 1licable to the vocal fremitus. Jntcr-^capular Rajion. — The intensity of the reso- nance here is nearly or quite as great as in the sterno- clavicular extremity of the infra-clavicular region. The resonance has in some |)ersons in this region the charac- ters of bronchophony. The intensity is always greater on the right sitle. The fremitus is more or less marked, and always more marked on the right than on the left side. Infra-scapular Region. — As a rule, the resonance in this region is stronger than over the scapula. It is always characterized by diffusion and distance. As in all the regions, it varies niuch in different persons, and is stronger, on the right than on the left side. These statements are also applicable to fremitus. Mammary and Infra-mammary Region>>. — The reso- nance is notably less than at the summit of the chest. The characters of bronchophony are never present. The intensity is greater on the right side. The same is true of fremitus. Axillary and Infra-axillary Regions. — The resonance in these regions, and especially in the axillary region, is greater than over the mammary and infra-mammary re- gions. It is, of course, stronger on the right side. The characters as contrasted with those of bronchophony, namely, distance and diffusion, are marked. Fremitus 82 AUSCULTATION IN HEALTH. is more or less marked, and, of course, more marked on the right than on the left side. Normal Bronchial Whisper. Prior to the publication of the author's work on the "Physical Exploration of the Chest," in 1856, signs in heaUh and disease relating to the whispered voice had received but little attention. In that work, and more fully in the second edition, published in 1866, a series of signs accompanying whispered words were described and named. As a point of departure for the study of the morbid signs thus obtained, of course the signs in health must first be studied. The sounds which are heard over different parts of the chest in health I have embraced under the name, the normal bronchial whis- per. The pertinency of this name is derived from the fact that the conduction of the sound produced by the whispered voice must be chiefly by the air contained in tlie bronchial tubes. The sound heard over the trachea and larynx may be distinguished as the laryngeal or tracheal whisper, the characters of which have been already stated (vide page 77). It will facilitate the study of the normal bronchial whisper, as well as of the morbid signs, to consider that the characters of the sounds produced with the whispered voice are identical with those produced by the act of expiration in all respects save intensity. Whispered words are produced, as a rule, by an act of expiration, the sounds being more intense generally than those which accompany even forced breathing. Curiously enough, there are exceptions to this rule. Some persons insist upon whispering with the act of inspiration, and there are some persons who have never acquired the ability to NORMAL BRONCHIAL WHISPER. 83 whisper. It will be at once evident that the pitch and quality of sounds produced by whispered words with the act of expiration, must be the sanae as those of the sounds of expiration in breathing. Selecting for the study of the normal bronchial whisper the same situations as in commencing the study of the normal respiratory murmur, and the nor- mal vocal resonance, namely, the middle of the chest in front, on the right side, and the infra-scapular region be- hind, with the whispered voice in these situations is heard, in most persons, a feeble, low-pitched blowing sound, these characters corresponding to those of the expiratory sound in forced breathing. The normal bronchial whis- per in these situations is not in all persons appreciable. In the infra-clavicular region, the bronchial whisper is heard, with variable intensity, in most persons. It is somewhat higher in pitch than the whisper below this reoion. It is louder and hioher in the sterno-clavicular than in the acromial extremity. In the former situation it has not infrequently a tubular quality. It is louder on the right than on the left side of the chest. It is sometimes heard on the right when it is inappreciable on the left side. When heard on both sides the pitch of the sound is higher on the left than on the right side. It will be observed that these variations correspond to those of the sound with expiration in the infra-clavicu- lar region [vide page 75). Occasionally w' hispered w^ords are partly transmitted, constituting incomplete wdiisper- ing pectoriloquy. In the scapular region the bronchial w^hisper is not infrequently wanting. It may be present on the right and not on the left side, and if present on both sides, it is ahvays louder on the right side. 84 AUSCULTATION IN HEALTH. In the inter-scapular region, as a rule, it is nearly or quite as marked as over the site of the primary bronchi in front. The pitch is more or less high, and has a tubular quality. It is louder on the right and higher in pitch on the left side, and in this situation there may be incomplete pectoriloquy. In the infra-scapular region, it is not infrequently -wanting. When present it is generally feeble, the pitch being low and the quality non-tubular or blowing. It is oftener wanting on the left than on the right side, and, if present on both sides, it is louder on the right side. In the mammary and infra- mammary regions it is not infrequently wanting, and the statements Just made with reference to the infra-scapular region arealike applicable to these, as, also, to the axillary and infra-axillary regions. AUSCULTATION IN DISEASE. 85 CHAPTER Y. AUSCULTATION IX DISEASE. The respiratory signs of Disease : — Abnormal modifications of the nor- mal respiratory sounds : — Increased vesicular murmur — Diminished vesicular murmur — Suppressed respiratory sound — Bronchial or tubular respiration — Broncho-vesicular respiration — Cavernous res- piration — Broncho-cavernous respiration — Vesiculo-cavernous res- piration — Amphoric respiration — Shortened inspiration — Prolonged expiration — Interrupted respiration. Adventitious respiratory sounds or rales: Laryngeal or tracheal rales — Moist bronchial rales, coarse, fine, and subci'epitant — Vesicular or crepitant rale — Cavernous or gurgling rale — Pleural friction rales, metallic tink- ling and splashing — Indeterminate rales. The vocal signs of dis- ease : Bronchophony — Whispering bronchophony — ^gophony — In- creased vocal resonance — Increased Bronchial whisper — Cavernous whisper — Pectoriloquy — Amphoric voice or echo — Diminished and suppressed vocal resonance — Diminished and suppressed vocal fremi- tus— Metallic tinkling. Signs obtained by acts of coughing or tus- sive signs. The importance of becoming perfectly familiar with the signs of health before entering upon the study of mor- bid signs, cannot be too strongly enforced. The aus- cultatory signs of disease, which are to be considered in this chapter, should not be studied until the student has made himself complete master of all the characters be- longing to the normal signs obtained by auscultation. Auscultation in disease embraces the signs produced by respiration, by the voice, and by acts of coughing. The respiratory signs will be first considered. 8 86 AUSCULTATION IN DISEASE. The Respiratory Signs of Disease. The signs produced by respiration may be classified as follows : 1st. Those which are abnormal modifica- tions of the normal respiratory sounds. 2d. Those which have no analogues in health, being entirely new or adv^entitious sounds. The latter are embraced under the name rale^. Abnormal Modifications of the Normal Respiratory Sounds. In order to appreciate the distinctive characters of the signs embraced in this class, the characters which distinguish the normal vesicular murmur must be kept in mind. The abnormal modifications which character- ize these morbid signs relate to intensity, pitch and quality of sound, together with certain alterations in rhythm. Twelve modifications or signs are included under this heading, namely : 1. Increased vesicular murmur; 2. Diminished vesicular murmur; 3. Suppres- sion of respiratory sound ; 4. Bronchial or tubular res- piration ; 5. Broncho-vesicular respiration ; 6. Cavernous respiration ; 7. Broncho-cavernous respiration ; 8. Ve- siculo-cavernous respiration ; 9. Amphoric respiration ; 10. Shortened inspiration; 11. Prolonged expiration; and, 12. Interrupted inspiration or expiration. These signs are to be studied, first, with reference to their distinctive characters severally, each being con- trasted, as respects these characters, with the other mor- bid respiratory signs as well as with the normal vesicu- lar murmur; and, second, with reference to the morbid physical conditions which they represent, that is, the diagnostic significance which belongs to each. MODIFICATIONS OF NORMAL SOUNDS. 87 Increased Yes'iGular Murmur. — This sign has but a single distinctive character, nanjely, increase of intensity. The murmur is abnormally loud, the characters of the normal vesicular murmur being in other respects not materially changed, that is, the pitch is low and the quality vesicular as in health. Now, it has been seen {vide page 73) that the intensity of the healthy murmur varies much in diiferent persons ; there is no ideal stand- ard of normal intensity by reference to which an abnor- mal increase is to be determined. Yet the increase under certain conditions of disease is such that the fact is suf- ficiently evident. It occurs on the healthy side of the chest when the respiratory function on the other side is annulled or much compromised by disease. This takes place in cases of pleurisy with large effusion, pneumonia, especially if more than one lobe be affected, obstruction of one of the primary bronchi, and pneumothorax. The sign does not possess great diagnostic importance, inas- much as the nature and extent of the disease are ascer- tained by the signs obtained on the affected side. The sign has been called supplementary and puerile respiration. If the murmur be much intensified, it may possibly be mistaken for other morbid signs, namely, bronchial or broncho-vesicular respiration. This error, howev^er, can never be made if the distinctive characters of these signs relating to pitch and quality have been correctly studied. Diminished Vesicular 3Iurmur. — The intensity of the vesicular murmur may be on the one hand diminished, when it is evident that in otiier respects there is no material change, and the murmur, on the other hand, may become so feeble that characters aside from the intensity are not determinable. From the latter fact it 88 AUSCULTATION IN DISEASE. follows that the murmur must sometimes be considered as only weakened, when, were the diminished intensity not as great, morbid changes in pitch and quality might be appreciable. The murmur is more or less weakened in cases of dila- tation of the air-cells, or vesicular emphysema, the sign, in these cases, being often accompanied by changes in rhythm, namely, a shortened inspiration and a prolonged expiration. Simple weakness of the murmur may also be incident to partial blocking of the air-vesicles with blood or serum in cases of j)iilmonary extravasation and oedema. A deficient expansion of the chest, either on one side or on both sides, occasions weakness of the re- spiratory murmur. Deficient expansion of one side, or of both sides, may be caused by paralysis, bilateral, or unilateral, of the costal muscles. A similar effect is caused by paralysis of the diaphragm. The incomplete descent of the diaphragm from pain, as in peritonitis, or from mechanical obstacles, as in peritoneal dropsy, preg- nancy, and abdominal tumors, weakens the respiratory murmur, the increased action of the costal muscles not being fully compensatory. Unilateral deficiency of ex- pansion of the chest is caused by pain in intercostal neu- ralgia, pleurodynia, acute pleurisy, and pneumonia; it is also caused by the presence of a stratum of liquid, air, or a thick layer of lymph between the lung and the chest- wall in pleurisy, hydrothorax,and pneumothorax. Swell- ing of the bronchial mucous membrane in bronchitis affecting the larger tubes, must diminish somewhat the intensity of the murmur. In primary bronchitis the murmur is diminished on both sides. In bronchitis affect, ing the smaller tubes, the murmur is greatly diminished, if not suppressed, on both sides. Incomplete obstruction MODIFICATIONS OF NORMAL SOUNDS. 89 of bronchial tubes from the presence of mucus, serum, blood, or pus, has this etfect over an area corresponding to the size of the tubes obstructed. Spasm of the bron- chial muscular fibres in paroxysms of asthma, diminishes, if it do not suppress, murmur on both sides. Another cause of diminution, unilateral, or within a limited space on one side, is the pressure of a tumor on bronchial tubes, as in cases of aneurism. A permanent contraction or stricture of bronchial tubes is another cause. Not in- frequently the pressure of an aneurismal tumor or an enlarged bronchial gland on a primary bronchus, occa- sions notable weakness of the murmur over the whole of one side; and the pressure of a tumor on the trachea weakens the murmur, more or less, on both sides. A foreign body in one of the primary bronchi w^eakens it on one side. Diminution of the calibre of the trachea or larynx from morbid growths, the presence of foreign bodies, fibrinous exudations, accumulations of mucus, submucous infiltration, spasms of the laryngeal muscles, and swelling of the mucous membrane, weakens, in pro- portion to the amount of obstruction, the murmur on both sides Avithout any material change in its quality and pitch. Weakened murmur at the summit of the chest, with- out other appreciable- abnormal characters, occurs in some cases of phthisis, due to obstructed bronchial tubes from coexisting circumscribed bronchitis, or to deficient superior costal movements of the chest, as well as to the presence of exudation in the air-vesicles. Diminished intensity of the vesicular murmur is thus seen to be a respiratory sign entering into the diagnosis of a considerable number of diseases, namely, emphy- sema, paralysis affecting the respiratory muscles, asthma, 90 AUSCULTATION IN DISEASE. abdominal affections interfering with the diaphragmatic movements, intercostal neuralgia, pneumonia, hydro- thorax, bronchitis, aneurismal and other tumors, per- manent constriction or stricture of bronchial tubes, lar- yngitis, oedema of the glottis, spasm of the glottis, the various lesions which occasion obstruction of the larynx or trachea, and phthisis. In determining a slight abnormal weakness of the re- spiratory murmur at the summit of the chest on the right side, the normal disparity between the two sides in this situation is to be borne in mind. The vesicular murmur is normally less intense on the right than on the left side. This sign occurring in so many diseases, it is obvious that, taken alone, that is, independent of other signs, it has not any special diagnostic significance. It is, how- ever, often of value in diagnosis, when taken in connec- tion with other signs. It is chiefly useful when it exists either over the whole or in a part of the chest on one side. Suppressed Respiratory Sound. — This sign is easily defined, namely, absence of all respiratory sound, as the name signifies. It cannot, of course, have any charac- ters relating to intensity, pitch, and quality. Su|)pression of respiratory sound represents the same physical conditions as diminished vesicular murmur; the physical conditions represented by the latter sign, existing in a greater degree, occasion absence of all sound. It suffices, therefore, to recapitulate the various conditions and diseases in connection with which the murmur may cither be diminished or suppressed. Sup- pression over portions of the chest may be due to dilata- tion of the air-cells in cases of emphysema. It occurs from the exclusion of air from the vesicles by the pros- MODIFICATIONS OF NORMAL SOUNDS. 91 ence of blood and serum in cases of pulmonary extrav- asation and cedema. Respiratory sound is sometimes wanting over lung solidified in cases of pneumonia and phthisis. Paralysis of tiie muscles concerned in respira- tion may possibly involve feebleness of the respiratory acts sufficiently to render the murmur inappreciable. In intercostal neuralgia, pleurodynia, acute pleurisy, and pneumonia, the movements of the affected side may be so much restricted as to abolish the murmur. In pleu- risy with much effusion, empyema, hydrothorax, pneumo- thorax, the murmur is suppressed over either a part or the whole of the affected side, the extent of the suppres- sion corresponding to the quantity of serum, pus, or air within the pleural cavity. Swelling of the mucous mem- brane in cases of bronchitis affectino; the laro;er bronchial tubes is never sufficient to suppress the murmur, but plug- ging of more or less of the tubes with mucus or other morbid products may have this effect. In cases of bron- chitis, the murmur is sometimes found to have disap- peared over a certain area, and to return after an act of expectoration. In bronchitis affecting the smaller tubes, suppression of the murmur is not infrequent. It occurs from spasm of the bronchial muscular fibres in cases of asthma. The pressure of a tumor, morbid growths, or deposits upon bronchi within the lungs, may abolish re- spiratory sound over a portion of the chest, and perma- nent stricture or obliteration of bronchial tubes may have this effect. Respiratory sound may be suppressed over the whole of one side from the pressure of an aneurismal or some other tumor upon one of the primary bronchi. If the tumor press upon the trachea, the obstruction may be sufficient to suppress the murmur on both sides. A foreign body lodged in a primary bronchus may suppress 92 AUSCULTATION IN DISEASE. the murmur on one side, and, lodged in the larynx or trachea, the murmur may be suppressed on both sides. The different affections of the larynx and trachea which, in proportion to the amount of obstruction, weaken the murmur, may render it inappreciable. Bronchial or Tubular Respiration. — The analogue of this sign is the normal laryngeal or tracheal respiration {vide page 70). The characters which distinguish the latter normal sign from the normal vesicular murmur, are those which are distinctive of the bronchial or tubular respiration. These characters, relating to the inspiratory and the expiratory sounds, are as follows: The inspira- tory sound is of variable intensity. Intensity does not enter into the distinctive characters of this sign ; the sound may be either louder or weaker than the inspira- tory sound in health. The })itch of the inspiratory sound is high. The quality is expressed by the term tubular; it is like the sound produced by blowing through a tube, this quality taking the place of that ex])ressed by the term vesicular in the normal respiration. The expiratory sound is prolonged ; it is as long as, or longer than, the sound of expiration, and is* usually louder. The pitch is still higher than that of the inspiratory sound. The quality, like that of the inspiratory sound, is tubular, thi.squality taking the place of the simple blowing quality of the expiratory sound in the normal vesicular murmur. With the normal rhythm of the respiratory acts there is a very brief interval between the sounds of inspiration and expiration, due to the fact that the inspiratory sound ends a little before the end of the inspiratory act. The morbid physical condition represented by this im- portant sign is either complete or considerable solidifica- tion of lung. Whenever the chest is auscultated over MODIFICATIONS OF NORMAL SOUNDS. 93 lung solidified, if there be not absence of respiratory sound, the sound is tubular. This significance renders the sif^n of diagnostic value in the diseases which involve solidification. The sign per se denotes simply this mor- bid physical condition ; the particular disease which ex- ists is ascertained by means of the associated signs and the symptoms. Solidification of lung is incident to several different diseases. In lobar })neumonia it is due to a fibrinous exudation within the air-vesicles. In phthisis it is caused by an exudation in the same situation. In chronic or fibroid pneumonia the lung is solidified by an interstitial growth. The compression of lung from either pleuritic effusion, an accumulation of air in the pleural cavity, or the pressure of a tumor, causes solidification by conden- sation. Collapse of pulmonary lobules also solidifies by condensation. Coagulation of blood within the air-vesi- cles (hsemorrhagic infarctus), and cancerous infiltration or growth, are other causes of solidification. In these different affections, if the solidification be complete or considerable, this sign is usually present; it is always present if there be not suppression of respiratory sound. It is sometimes the case that either the inspiratory or the expiratory sound is wanting. The characters of the sign suffice for its recognition if either the inspiratory or the ex[)iratory sound be alone present; the pitch and the quality are distinctive. Both sounds are often so intense that they are diffused more or less without the limits of the solidified portion of lung. The expiratory sound, being more intense than the inspiratory, is trans- mitted further tlian the latter. This ex])lains the con- junction sometimes of a vesicular inspiration with a tubular expiration ; and a cavernous inspiration may be 94 AUSCULTATION IN DISEASE. conjoined with a tubular expiration, showing the prox- imity of solidified lung in the former case to healthy lung, and, in the latter case, to a pulmonary cavity. The sound may seem near the ear or to come from a certain distance. The latter is appreciable in some cases of large pleuritic effusion ; the tubular respiration is more or less distant, and it is sometimes diffused over the whole of the side which is filled with liquid. Broncho-vesicular Respiration. — This name was intro- duced by me in 185G to denote the combination, in vary- ing proportions, of the characters of the bronchial or tubular, and of the normal vesicular respiration. The name expresses such a combination. It embraces modi- fications to which have been applied the terms, rudcj rough, and harsh respiration, ajid those included by Ger- man authors under the name indeteiininate respiratory sounds. The sign represents the different degrees of solidifica- tion of lung, between an amount so slight as to occasion only the smallest appreciable modification of the respira- tory sound, and an amount so great as to approximate closely to the degree giving rise to bronchial or tubular respiration. In other words, all the gradations of re- spiratory modifications, caused by incomplete or an in- considerable solidification, which fall short of bronchial or tubular respiration, are embraced under the name broncho-vesicular. The gradations correspond to the amount of solidification, that is, tlieyshow the solidifica- tion to be either very slight, slight, moderate, or nearly sufficient to be considered as considerable or complete. The sign is therefore important as evidence, first, of the existence of solidification, and second, of the degree of solidification. MODIFICATIONS OF NORMAL SOUNDS. 95 Analyzing tliis sign, the nnost distinotive feature is the combination of the vesicular and the tubular quality in the inspiratory sound. These two qualities niay be combined in variable proportions. The pitch of the sound is raised in proportion as the tubular predominates over the vesicular quality. The expiratory sound is more or less prolonged, tubular in quality, and the pitch is raised. The prolongation of this sound, its tubular quality, and the highness of pitch, are proportionate to the predominance of the tubular over the vesicular quality in the inspiratory sound. If the solidification of luncr be slio^ht, tlie characters of the normal vesicular respiration predominate ; that is, the inspiratory sound has but a small proportion of the tubular quality, and is but little raised in pitch, the expiratory sound being not much prolonged, its tubularity not marked, the pitch not high. If, on the other hand, the solidification of lung be almost enough to give a bronchial respiration, the inspiratory sound has only a little vesicular quality, the tubular quality ])redominating, the pitch proportionately raised ; and the expiratory sound is prolonged, tubular, and high, nearly to the same extent as in the bronchial respiration. The less the solidification the more the characters of the normal vesicular predominate over those of the bronchial respiration, and, per contra, the greater the solidification the more the characters of the bronchial predominate over those of the normal vesicular respira- tion. Daily auscultation in a case of lobar pneumonia during the stage of resolution, affords an opportunity to study all the gradations of this sign. After resolution has made some progress, the inspiratory sound is no longer ])urely tubular, but the ear ap])reciates a little admixture of the vesicular quality, and the pitch is 96 AUSCULTATION IN DISEASE. sliglitly lowered. As resolution goes on, the vesicular quality increases, the pitch is correspondingly lowered, until, at length, no tubularity remains, and the pitch becomes normal. Meanwhile, as the vesicular quality increases in the inspiratory sound, the expiratory sound is less and less prolonged, high and tubular, until it be- comes, as in health, short, low, and blowing. The broncho-vesicular respiration is an important diagnostic sign in all the affections which involve partial solidification of lung. In lobar pneumonia, as just stated, it denotes the progress made from day to day in resolu- tion. It is found also in an earlier stage, before the solidification is sufficient to give rise to a purely bron- chial respiration. It is a valuable sign in phthisis, afford- ing evidence, not only of the fact of solidification, but of its degree and extent. The sign enters into the diag- nosis of interstitial pneumonia, hsemorrhaglc infarctus, condensation of lung from the pressure of either liquid, air, or a tumor, and from collapse of pulmonary lobules. It may be stated with respect to this sign, that it is always present if the lung be partially solidified, pro- vided there be not either suppression of respiratory sound, or such a degree of feebleness that the distinctive characters are undeterminable. As with the bronchial respiration, so with the broncho-vesicular, either the in- spiratory or the expiratory sound may be wanting. The characters of the sign are then to be determined as they are manifested in the sound which is present, namely, the combination of the vesicular and the tubular (juality, with more or less elevation of pitch, if only an insj)ira- tory sound may be heard, and the amount of prolonga- tion, tubularity, and elevation of pitch, if there be only an expiratory sound. MODIFICATIONS OP NORMAL SOUNDS. 97 In deteriiiininf^ the presence of this morbid sign, at tlie summit of tlie chest on the right side, it is to be borne in mind that the respiratory murmur on this side has, in health, as compared with the res})iratory murmur at tlie summit on the left side, more or less of the char- acters of the broncho-vesicular respiration (^Me Normal Broncho- vesicular Respiration, page 94). Caver-nous Respiration. — The modifications which con- stitute the distinctive characters of this sign, are ])roduccd by the entrance of air into a cavity with the act of inspi- ration, and its exit from the cavity with the act of expi- ration. This passage of air into and from a cavity can only take place where the walls of the cavity collapse more or less in expiration and exj)and in inspiration. Pulmonary cavities occur chiefly in cases of phthisis. They occur, but with com|)arative infrecpiency, as a re- sult of circumscribed abscess and gangrene of lung. A well-marked cavernous respiration has characters which are highly distinctive when this sign is contrasted, on the one hand, with either the bronchial or broncho- vesicular respiration, and, on the other hand, with the normal vesicular murmur. These distinctive characters relate both to the inspiratory and expiratory sound. The inspiratory sound is neither vesicular nor tubular in quality, and the pitch is low as compared with the bron- chial respiration. As regards quality, we may say of it, as of the expiratory sound in the normal vesicular respi- ration, it is simply a blowing sound. The expiratory sound has the same quality as the inspiratory, and it is lower in pitch. Its duration is variable. The intensity of both the inspiratory and the expiratory sound varies; intensity does not enter into the distinctive characters of this sign more than into those of the bronchial and the 98 AUSCULTATION IN DISEASE. broncho-vesicular respiration. These distinctive char- acters of the cavernous respiration, as regards pitch and quality, especially of the expiratory sound, were first pointed out by me in 1852.^ Prior to this date the bronchial and the cavernous respiration were considered as having identical characters, or, at all events, as not distinguishable from each other. Following Skoda, these two signs are still considered as essentially identi- cal by German authors. With a practical knowledge of the foregoing characters distinctive of the cavernous respiration, there is no difficulty in discriminating this sign from the bronchial respiration. The sign is more likely to be confounded with the normal vesicular mur- mur, inasmuch as it differs from the latter only in the absence in the inspiratory sound of the vesicular quality. Against this error the student is to be cautioned. It is most likely to be made when the inspiratory sound is much weakened, and, consequently, the vesicular quality less distinctly appreciable than when the sound is more or less intense. A cavernous respiration is limited to a space more or less circumscribed, the area corresponding to the site and the size of the cavity. Occurring, for the most part, in cases of phthisis, it is much oftener found at the summit than elsewhere over the chest. It is not constantly found where there is a cavity witii flaccid walls. It may be temporarily suppressed by the presence of liquid within the cavity, and by obstruction of the orifices communi- cating with bronchial tubes, or of the latter. It may be wanting at one moment, and an act of expectoration may 1 Prize Essay on Variations of Pitch in tlie Sounds obtained by Percussion and Au-;cultation. Transactions of the American Medi- cal Association, 1852. MODIFICATIONS OF NORMAL SOUNDS. 99 cause it to reappear. Hence absence of cavity cannot be predicated on the absence of tlie sign at a single ex- amination. Moreover, if a cavity be not situated near the pulmonary superficies, and solidified lung intervene between it and the walls of the chest, the cavernous sign may be drowned in a loud bronchial respiration. For this reason, while the cavernous sign is positive evi- dence of a cavity, the absence of the sign is not proof that a cavitv does not exist. In some cases of perforation of lung with pneumo- thorax, the passage of air to and fro through the perfor- ation may give rise to the cavernous respiration. As a rule, however, under these circumstances, another sign is produced, namely, the amphoric respiration. Broncho -cavernous Respiration. — In this sign, as the name denotes, the characters of the bronchial and the cavernous respiration are combined. These characters may be combined in different ways, as w^ell as in varia- ble proportions. If a cavity be situated in proximity to solidified lung, the quality and pitch of the inspiratory and the expiratory sound may show an admixture of the characters of the two signs, and to a practiced ear, the combination is distinctly recognizable. This is one of the forms of broncho-cavernous respiration ; the sounds are not sufficiently high and tubular for bronchial, nor sufficiently low and blowing for cavernous respiration. Another form consists of an inspiratory sound, the first part of which is tubular, and the latter part cavernous. Examples of this form are not extremely infrequent. This form has been recently described by Seitz under the name, " metamorphosing respiration.''^ Still another form is a cavernous inspiratory, with a bronchial or tubular expiratory sound. In the latter form, the bron- 100 AUSCULTATION IN DISEASE. chial expiration proceeds from solidified lung situated near tlie cavity, the intensity of the sound being suffi- cient to drown the cavernous expiration. When, as often happens, a cavity is situated in close proximity to, or, it may be, surrounded by solidified lung, the cavernous and the bronchial respiration are, as it were, in juxtaposition, and such instances offer an excellent opportunity to study the points distinguishing these signs from each other; and, generally, at a short distance the normal vesicular murmur may be found, so that both morbid signs may be compared with the latter. Within a circumscribed area, sometimes, are exemplified the characters of the normal murmur, and of the two morbid signs just mentioned, together with those of the broncho- vesicular respiration. Vesiculo- cavernous Respiration. — It is sometimes evi- dent that the vesicular and the cavernous quality are combined in the inspiratory sound. This occurs when a cavity is surrounded, not by solidified, but by healthy lung. Under these circumstances, over the site of the cavity, the inspiratory sound may be as loud as, or louder than that around the cavity, but the quality is not purely cavernous; some vesicular quality is appreciable. A vesiculo-cavernous respiration, then, is a cavernous res- piration plus some vesicular quality derived from the air- vesicles which are proximate to the cavity. This sign is corroborated by other associated signs showing the ex- istence of a cavity and its localization. Amphorie Respiration. — The term amphoric has a significance when applied to auscultatory sounds, analo- gous to that which it has in percussion ; it denotes a musical intonation which may be compared to the sound produced by blowing upon the open mouth of a decanter MODIFICATIONS OP NORMAL SOUNDS. 101 or pliial. Whenever the respiratory sound has this in- tonation, it denotes a space containing air which is not expelled with the act of expiration. Air in the pleural cavity, with perforation of hin^, is the physical condition most frequently represented by this sign. It is a valu- able diagnostic sign in cases of pneumothorax ; but it is not always present in that affection, certain accessory conditions being requisite, namely, perforation above the level of liquid, and an unobstructed communication of the bronchial tubes, through the opening, with the pleu- ral space containing air. While, therefore, its presence is significant of pneumothorax, its absence is by no means sufficient to exclude this affection. Not infrequently, it is a sign of phthisical cavity with rigid walls which do not collapse with the act of expiration. The same con- tingencies affect its production here as in cases of pneu- mothorax. Whenever amphoric respiration is present, if pneumothorax be excluded by the absence of the other signs which are diagnostic of this affection, the sign is proof of the existence of a pulmonary cavity, the walls of which aie not flaccid. The sign then takes the place of the ordinary cavernous respiration which has been described. The amphoric sound may accompany either respira- tion or expiration, or both. Slwrtened Inspiration. — The inspiratory sound is somewhat shortened in bronchial or tubular respiration. This modification enters into the characters of that sign, the quality of the sound being tubular;, and the pitch high. The shortening is due to the sound ending before the inspiratory act ends ; the sound is said to be unfinished. Shortening of the sound occurs, however, when it is not an element in the bronchial respiration. The shortening 9 102 AlfSCULTATION IN DISEASE. is then due to tlie sound not beginning with the inspira- tory act; this is distinguished as deferred inspiratory sound. A deferred inspiratory sound not tubular in quality, but more or less vesicular, and not notably raised in pitch, is a sign of pulmonary or vesicular emphysema. It is a sign of value in connection with the diagnosis of that disease. The student should note the distinctions just stated which relate to pitch and quality. Suppose an inspira- tory sound to be present without an expiratory sound: if the sound be shortened at the end of the inspiration, the pitch high and the quality tubular, it is bronchial respiration, denoting complete or considerable solidifica- tion of lung, but if the shortening be at the beginning of respiration, the pitch comparatively low, and vesicular quality be appreciable, the sign denotes emphysema. The differential points thus are, the inspiratory sound either unfinished or deferred, the pitch either high or low, and the quality either tubular or vesicular. Attention to these points is essential in order to avoid error in the interpre- tation of the sign. Prolonged Expiration. — The length of the expiratory sound in health varies in different persons. The sound is sometimes considerably prolonged ; it may be nearly as long as the sound of inspiration. There is no diffi- culty in recognizing this as a normal peculiarity, from the fact that the murmur has the pitch and quality of health. An unusual length of the expiratory sound, within the range of health, is usually observed at the summit of the chest, and especially on the right side. It is important to bear in mind that at the summit of the chest on the right side, and sometimes also on the left side, a pro- longed expiratory sound, more or less raised in pitch, and tubular in quality, may be a normal peculiarity. It fol- MODIFICATIONS OF NORMAL SOUNDS. 103 lows that a prolonged, and even a high and tubular ex- piration at the summit of the chest, must not be reckoned as a morbid sign unless it be associated with other signs denoting disease. The laws of the disparity between the two sides of the chest at the summit are to be taken into account {vide p. 74). If the expiration be longer on the left than on the right side^ it is abnormal ; so, also, is a high-pitched tubular expiration heard on the left and not on the right side. The significance of an abnormally prolonged expira- tion depends on its pitch and quality. If it be high and tubular, it denotes solidification of lung. It is, in fact, bronchial respiration. As already stated, in bronchial or tubular respiration, the inspiratory sound is some- times wanting, and the presence of the sign is then to be determined by the characters, relating to pitch and qual- ity, of the expiratory sound. The same statement holds true with respect to broncho-vesicular respiration, when this approximates to the bronchial. At the summit of the chest, the characters of the inspiratory sound, and associated morbid signs, always enable the auscultator to determine whether a prolonged high and tubular expira- tion be, or be not, abnormal. A prolonged expiration, which is low in pitch and blowing in quality, that is, with the characters of health, aside from length, may belong to a cavernous expiration. This is to be deter- mined by the characters of the inspiration, and by other associated signs. Exclusive of cavernous respiration, an abnormally prolonged expiratory sound of low pitch and non-tubular, denotes vesicular emphysema. It is asso- ciated then with a weakened and deferred inspiratory sound. A prolonged expiratory sound, in cases of emphy- sema, is invariably low and non-tubular. If it have 104 AUSCULTATION IN DISEASE. not these characters, it is not a sign of emphysema, but belongs to bronchial or broncho-vesicular respiration. Attention to these differential points is to be enjoined upon the student. A prolonged expii'ation at the summit of the chest on the right side is sometimes incorrectly considered to be evidence of phthisis. It is to be recollected, in the first place, that prolongation of this sound with a normal pitch and quality, is never evidence of solidification of lung either from phthisis or any other disease; and in the second place, even if the pitch be high, and the qual- ity tubular, that it is not to be regarded as abnormal, provided the inspiratory sound is unchanged, and other signs of disease are not present. At times in bronchitis there is a prolonged expiratory sound which may be dis- tinguished as a sonorous expiration, not amounting to a rale. This is liable to be mistaken for broncho-vesicu- lar breathing. Interrupted Respiration. — To this sign have been ap- plied other names, such as jerking^ wavy, cogged icheel, and by French writers the names entrecoupee and sacca- dee. The modification is either of the inspiration or of the expiration, or of both. The inspiratory, however, much more frequently than the expiratory, sound is in- terrupted. Tlie sound, instead of being continuous, is broken into one, two, or more parts. This is the char- acteristic of the sign. If at the same time there be altera- tions in pitch and quality, the interruption is merely incidental to other signs ; namely, the bronchial, broncho- vesicular, or cavernous respiration. To constitute it a distinct sign, the interruption must be the only appreci- able change. As a distinct sign it has but little diag- nostic value. MODIFICATIONS OF NORMAL SOUNDS. 105 Interrupted respiration is sometimes found in healthy persons. It is confined to the summit of the chest, and oftener on the left tiian the right side. Existing without anv other signs, therefore, it is not evidence of disease. It is of value only in the diagnosis of phthisis. Associ- ated with other signs, when the latter are not marked, it is entitled to a certain amount of weight in the diagnosis. Interrupted respiratory sounds, of course, occur when there is interruption in the respiratory movements. This happens in cases of pleurisy, pleurodynia, or intercostal neuralgia. Owing to the pain caused by the movements in respiration, the })atient may breathe, not continuously, but with a series of jerking movements. Sometimes in- terrupted breathing is observed in persons who are ex- cited or agitated when auscultation is practiced. In all these instances, interruption in the respiratory sounds is found over the ^vliole chest, whereas, when it is an ab- normal sign in cases of phthisis, it is limited to the sum- mit on one side of the chest, and there is no interruption manifested in the mode of breathing. Reviewing the foregoing signs, they may be distributed into three classes, as ibllows : 1st. Signs, the distinctive characters of which relate to either the absence or the intensity of sound. This class embraces, (a) increased intensity of the vesicular murmur; (b) diminished in- tensity of the vesicular murmur; and (c) suppression of respiratory sound. 2d. Signs, the distinctive characters of which relate especially to pitch and quality. In this class belong, (a) bronchial or tubular respiration ; (b) broncho-vesicular respiration ; (c) cavernous respiration; (d) broncho-cavernous respiration ; (e) vesiculo-cavern- ous respiration, and (f) amphoric respiration. 3d. 106 AUSCULTATION IN DISEASE. Signs, the distinctive characters of which relate especially to rhythm, namely, (a) shortened inspiration ; (b) pro- longed expiration ; and (c) interrupted respiration. Adventitious Respiratory Sounds, or Rales. Adventitious respiratory sounds, or, adopting the French term, rales, are distinguished from the morbid signs already considered, by the fact that they have no analogues in health ; in other words, they are not normal sounds abnormally modified, but wholly new sounds. A convenient classification of these signs is based on the different anatomical situations in whicli they are pro- duced. This classification is as follows : 1st. Laryngeal and tracheal rales ; 2d. Bronchial rales ; 3d. Vesicular rales; 4th. Cavernous rales; 5th. Pleural raies; and 6th. Indeterminate rales. Compared with each other, as regards their characters, they admit of being divided into dry and moist rales, the latter being evidently due to the presence of liquid. Laryngeal and Tracheal Rales. — The rales produced within the larynx and trachea may be either moist or dry. The moist or bubbling sounds are produced when mucus or other liquid accumulates in these sections of the air-tubes. This occurs frequently in the moribund state, and the sounds are then known as the '^ death rattles.^' When not incident to this state, they denote either insen- sibility to the presence of liquid, as in coma, or inability to effect the removal of the liquid by acts of expectoration. The sounds are heard at a distance. They exemplify, on a large scale, moist or bubblingauscultatory sounds which are produced within the bronchial tubes. The dry rales j)roduced within the larynx or trachea are caused by spasm of the glottis, and by diminution of the calibre, MOIST BRONCUIAL RALES. 107 either at or below the glottis, from oedema, exudation, the presence of a foreign body, or the pressure of a tumor. The dry sounds are distinguished as whistling, wheezing, crowing, whooping, etc. They are heard at a distance, and they also exemplify auscultatory sounds representing analogous conditions in the bronchial tubes. Characteristic sounds produced at the glottis by spasm enter into the diagnosis of certain aifections, namely, laryngismus stridulus, [)ertussis, croup, and aneurism involving: excitation of the recurrent larvno-eal nerve. Other sounds are due to paralysis of the laryngeal muscles. Again, dry sounds, called stridor, produced by stenosis of the trachea from the pressure of an aneu- rismal or other tumor, cicatrization of ulcers, and morbid growths, are of diagnostic importance. Although audi- ble without auscultation, these different sounds, with reference to the precise situation at which they are pro- duced, may sometimes be studied with advantage by means of the stethoscope. Moist Bronchial Rales. The moist bronchial rales are bubbling sounds pro- duced in diiferent branches of the bronchial tree. They are sounds of which the "tracheal rattles^' are an ex- aggerated type. They may be imitated by blowing into liquids through tubes differing in size. They may also be produced in the lungs of the sheep or the calf, after removal from the body, by injecting into the bronchi glycerin or some other liquid, and imitating the respi- ratory acts by means of a pair of bellows, auscultation being practiced with the stethoscope ap])lied upon the lung, or with several thicknesses of cloth intervening. The bubbles seem to be laro;e or small, accordino; to the 108 AUSCULTATION IN DISEASE. size of the bronchial tubes in which they are produced. Apparent differences in the size of the bubbles are dis- tinguished by the names coarse and fine. In the primary and secondary bronchial branches the moist sounds are relatively quite coarse; they are less so in tubes of the third or fourth dimensions; in smaller tubes they be- come fine, and in those of minute size they become ex- tremely fine. Extremely fine bubbling sounds consti- tute what is known as the subcrepitant rale, so called because it approaches in character to the crepitant rale produced within the air-vesicles and bronchioles. We may thus judge of the size of the bronchial tubes in which the rales are produced by their comparative coarseness or fineness. Frequently, however, coarse and fine rales are intermingled, and generally those which are either coarse or fine are not uniform, but appear to be of unequal size. In all the varieties of the moist bronchial rales, tne bubbling character of the sounds is sufficient! V distinctive for their recognition. The differ- entiation of the subcrepitant from the crepitant rale alone involves some nice points of distinction. Coarse bubbling rales sometimes occur in acute bron- chitis affecting the larger bro.ichial tubes. Their occur- rence is exceptional, because, in general, the mucus within the tubes does not accumulate sulficiently and is too consistent for the production of bubbling sounds. These rales occur in cases in which the mucus is un- usually thin and either more abundant than usual or an accumulation takes place in consequence of inability to expectorate freely. These conditions are wanting in the majority of the cases of ordinary acute bronchitis. A muco-purulent liquid in cases of chronic bronchitis is better suited for the production of bubbling sounds than MOIST BRONCHIAL RALES. 109 simple mucus. Moreover, coarse rales are heard oftener in children than in adults, because the former do not voluntarily expectorate as freely as the latter. Serous transudation (bronchorrhoea) into tubes of large size may give rise to coarse bubbling rales, and also the presence of blood in some cases of profuse haemorrhage. In bron- chitis and bronchorrhoea the rales are heard on both sides of the chest. The bubbling rales, whether coarse or fine, are heard cither with the act of inspiration or of exj)iration, or with both acts. Fine bubbling sounds and the subcrepitant rale occur in various pathological connections. The charac^ters of the subcrepitant rale are to be borne in mind with refer- ence to the discrimination from the crepitant. The most distinctive character is the moist sound or bubbling; this is sufficiently appreciable. Other characters are, their occurrence frequently, but not constantly, in expi- ration as well as in inspiration, and the inequality of the fine bubbling sounds. The subcrepitant rale, existing over the chest on both sides, is diagnostic of bronchitis affecting the smaller bronchial tubes (capillary bronchitis), when taken in connection with other signs and the symptoms. The rale exists on both sides, because this, as well as bronchitis affecting the larger tubes, is a bilateral affection. The sign is of great j)ractical value in the diagnosis of that variety of bronchitis. The rale also occurs on both sides, and is more or less diffused in pulmonary oedema. The connection with the latter affection is shown by the associated j)hysical signs, together with the symptoms. In so-called capillary bronchitis, the bubbling is due to the presence of thin mucus, and in pulmonary oedema 10 110 AUSCULTATION IN DISEASE. to serous transudation within the small bronchial rami- fications. Fine bubbling or a subcrepitant rale has other patho- logical connections, as follows: 1. It occurs in lobar pneumonia during the stage of resolution. Here it is due to the presence of mucus from a bronchitis limited to the aifected lobe or lobes, and, in a measure, to liquefied pneumonic exudation. It is con- sidered as denoting commencing and progressing reso- lution in pneumonia. Sometimes it is intermingled with rales which are more or less coarse. 2. In circum-cribed pneumonia, hsemorrhagic infarc- tus, and pulmonary apoplexy, the fine or subcrepitant rale, often associated with those which are more or less coarse, denotes the presence of mucus or of blood within the bronchial tubes. The rales are localized in space, or in spaces, corresponding to the situation and extent of the affection. 3. During and shortly after a haemoptysis, fine rales limited to a particular situation are sometimes heard, proceeding from blood in the small bronchial tubes, and indicating the situation of the haemorrhage. 4. A purulent liquid admits of bubbling much more readily than mucus ; hence, in cases of chronic bron- chitis with an expectoration of pus, fine and coarse bron- chial rales are more frequent tlian in acute bronchitis. Pus, also, may be present within bronchial tubes of small size, not as a product of bronchitis, but from the evacua- tion of an abscess of either the pulmonary parenchyma, of the liver or some other adjacent part, and from per- foration of lung in some cases of empyema. 5. In the different stages of phthisis, moist bronchial rales are usually present. The liquid in the tubes, if the MOIST BRONCHIAL RALES. Ill disease be advanced, is derived, in part, from associated bronchitis, and, in part, from liquefied tuberculous ex- udation. The bubbling sounds may be more or less coarse or fine, and both are often intermingled. Early in the disease, before softening of the exudation has taken place, fine bubbling, or the subcrepitant rale, lim- ited to the summit of the chest, is an important diagnostic sign. It belongs among the accessory physical signs on which the diagnosis may depend. Here the liquid is derived from a coexisting circumscribed bronchitis. In cases of fibroid phthisis, or cirrhosis of lung, moist rales, coarse and fine, are generally more or less abun- dant and diffused over the whole, or the greater part, of the chest on the affected side. In the foregoing account of the moist bronchial rales, the subcrepitant rale is not reckoned as a sign distinct from fine bubling sounds. Inasmuch as the mechanism and the significance are the same, and it is not easy to draw a line of demarcation between the two, the distinc- tion is unimportant. It is sufficient to bear in mind that very fine bubbling sounds are called subcrepitant, be- cause they are somewhat analogous to the crepitant rale, The points which distinguish the latter are, however, w-ell-marked, as will appear when the characters of that sign are considered. The moist rales are often called mucous rales. This name is obviously inappropriate, since, not only are the sounds produced by other liquids than mucus, but other liquids are best suited for their production, especially in the large and medium-sized tubes. The several varieties of the moist bronchial rales may be produced by the injection of a liquid in varying quantity into the bronchi of the lungs removed from 112 AUSCULTATION IN DISEASE. the body of an animal of sufficient size, e. g. of the sheep or calf. The moist bronchial rales, whether coarse or fine, vary in pitch accordingly as the lung surrounding the tubes in which they are produced is, or is not, solidified. If the lung be solidified, the pitch is high ; if there be no solidification, the pitch is comparatively low. Tims, the pitch of the rales is high in the second stage of pneu- monia and in phthisis with considerable solidification, whereas the pitch is low in bronchitis and pulmonary oedema. If, therefore, the respiratory sound be sup- pressed, it is easy to determine by the pitch of these rales whether the lung be solidified or not, and to judge measurably of the degree of solidification. Attention to the pitch in connection with these rales is sometimes of value in diagnosis. Dry Bronchial Rales. All adventitious sounds which are not moist, produced within the air-tubes below the trachea, are embraced under the name dry bronchial rales. The sounds are many and varied in character. They are often musi- cal notes. Frequently they are suggestive of certain familiar sounds, such as the chirping of birds, the cry of a young animal, snoring in sleep, cooing of pigeons, humming of the mosquito, the note of the violoncello, etc., etc. They are often heard at a distance, and characterized as wheezing sounds. An interrupted or clicking sound is not uncommon. All these varieties are practically unimportant, and it would be a needless refinement to consider particular varieties as distinct signs. The only distinction which it is desirable to make is into the sibilant and sonorous rales. This dis- DRY BRONCHIAL RALES. 113 tinction is based on difference in pitch ; sibilant rales are hi^^h, and sonorous rales are low in pitch. As a rule, the sibilant rales are produced in the small and the sonorous rales in the larger sized bronchial tubes. The sounds may accompany either inspiration or expiration, or both. The sibilant and sonorous rales are often in- termingled. There may be sibilant rales with inspira- tion, and sonorous rales with expiration, within the same situation. Moreover, these rales are found often to vary from minute to minute, being at one instant sibi- lant and at another sonorous. Students are liable to confound sonorous rales with bronchial breathing and sometimes friction- sounds. The ])hysical condition represented by the dry rales is diminished calibre of the air-tubes at certain points, and especially in consequence of spasm of the bronchial muscular fibres. The latter constitutes the essential pathological condition in a paroxysm of asthma; and in this affection the dry rales are always marked. Their diagnostic importance relates chiefly to asthma. Both sibilant and sonorous rales are present and diff'used over the entire chest. Wheezing sounds with expiration are heard by the patient, and by others at a distance. A single paroxysm of asthma affords an opportunity for the student to observe all the varieties and fluctuations of these rales. Taken in connection with other signs and the symptoms, the rales are pathognomonic of asthma. More or less spasm of the bronchial muscular fibres occurs in certain cases of bronchitis, without being suffi- ciently great and extensive to give rise to a paroxysm of asthma, or even any embarrassment of respiration. Under these circumstances the rales are less marked and diffused. An asthmatic element may be said to 114 AUSCULTATION IN DISEASE. enter, more or less, into these cases. Narrowing of bronchial tubes by tenacious mucus which gives rise to no bubbling sounds, and, perhaps unequal swelling of the mucous membrane, may also occasion sibilant and sonorous rales. Dry rales at the summit of the chest are not infrequent in cases of phtiiisis, due to spasm, the presence of mucus, or to swelling of the mucous membrane. They are some- times quite annoying to phthisical patients. Clicking sounds are suggestive of the sudden separa- tion of tenacious mucus from the walls of the bronchial tubes. These are sufficiently common in bronchitis and in phthisis. Vesicular or Crepitant Rale. This is the only vesicular rale. It is usually con- sidered to be produced within the air-vesicles, but prob- ably, the terminal bronchial tubes or bronchioles par- ticipate in its production. It is to be distinguished from very fine bubbling sounds, or the subcrepitant rale. The points of distinction are as follows : The sounds are not moist but dry ; they are crackling, not bubbling in character. They may be de- fined to be very fine, dry, crackling sounds. This point of difference is very distinctive. There are, however, other differential points. The crackling sounds are equal, whereas, fine bubbling sounds are unequal, that is, they give the impression of bubbles of unequal size. The crepitating sounds are heard at the end of the inspira- tory act, and especially at the end of a forced inspira- tion, the subcrepitant rale, on the other hand, being heard often with or near the beginning of inspiration, and, per- haps, ceasing before the end of the inspiratory act. An- other distinctive feature is the abrupt development of VESICULAR OR CREPITANT RALE. 115 tlie crepitant rale; there Is a shower of crackles, as it were, at the end of a forced inspiration. Finally, the rale is never heard in expiration. The apparent excep- tions to this statement are instances in which the crepi- tant and the subcrepitant rale are associated. This is not very infrequent, and, with a practical knowledge of the characters of each, it is by no means difficult to ap- preciate the combination of the two signs. In fact, the combination affords an excellent opportunity to illustrate the distinctive characters of each ; the fine bubbling at or near the beginning of inspiration, followed by the fine crackling at the end of this act, and the former perhaps reproduced in the act of expiration. There are various modes in which the crepitant rale may be irnitated; for examples, rubbing together a lock of hair near the ear, throwing fine salt upon live coals or into a heated vessel, igniting a train of gunpowder, and alternately pressing and separating the thumb and finger moistened with a solution of gum arable and held near the ear. A perfect representation is afforded by squeezing a piece of an artificial preparation known as the india-rubber sponge, and observing the sound pro- duced by the separation of the walls of the interstices when the piece expands from its elasticity. This pre})a- ration exemplifies the true mechanism of the sign as described, first, by the late Dr. Carr, of Canandaigna, N. Y., in an article published in the American Journal of 31edical Sciences, in October, 1842.^ Expansion of the lungs of the sheep or calf, after removal from the body, the stethoscope being applied to the lung-surface, gives, in certain situations, a well-marked crepitant rale. "• Vide article by the author in the New York Monthly Med. Journ. for Feb., 1869. 116 AUSCULTATION IN DISEASE. The crepitant rale is the diagnostic sign of pneumonia. It very rarely occurs in any other })athological connec- tion. Of all respiratory signs, this is most entitled to be called pathognomonic. It belongs especially to the first stage of acute pneumonia. It is not invariably present, but it occurs in the majority of cases of acute pneumonia. In the second stage, or tiie stage of solidifi- cation, the rale generally disappears. It not infrequently is rej)roduced in the stage of resolution, and it is then called the returning crepitant rale. In the latter stage it is often found in combination with the subcrepitant rale. The practical value of this sign relates chiefly to the diagnosis of pneumonia. It is stated that the crepitant rale is sometimes found in cases of pulmonary oedema, and during or directly after an attack of haemoptysis. If it ever occur in these cases, the instances must be extremely rare. The state- ment is perhaps based on the occurrence of the subcrepi- tant, this being confounded with the crepitant rale. It occurs transiently under the following circumstances: A patient wlio has been confined for some time in bed, lying on the back, and much enfeebled with any disease, if suddenly raised to a sitting posture and auscultated, a crepitant rale is often found on the posterior aspect of the chest at the end of a forced inspiration. The rale disappears after a few forced inspirations. It is heard, not on one side only, but on l)oth sides. The explana- tion is, that during the recumbent posture continued for some time, and the patient breathing feebly, enough of the air-vesicles and bronchioles become agglutinated by means of a little sticky transudation to give rise to crackling sounds in a few forced inspirations. It may be CAVERNOUS OR GURGLING RALE. 117 of use to mention that if the stethoscope be applied to the anterior surface of a cliest much covered with hair, the movements of the pectoral extremity of the instru- ment in the act of inspiration may produce a sound iden- tical with the crepitant rale. A crepitant rale at the summit of the chest, within a circumscribed space, is one of the accessory signs of phtliisis. It denotes a circumscribed pneumonia which clinical experience shows to be generally secondary to phthisis; hence the diagnosti(3 significance of the sign. Cavernous or Gurg^ling Rale. A pulmonary cavity of considerable size, containing a certain quantity of liquid, and communicating freely with bronchial tubes, furnishes a rale which is characteristic. The character of the sound is expressed as fully as possible by the term gurgling. The sound is produced by large bubbling and the agitation of the liquid within the cavity. It may be compared to the sound produced by the boiling of a liquid in a flask or large test-tube. The sound is sometimes high pitched and amphoric, but generally it is low in pitch. It is heard with more or less intensity within a circumscribed space almost in- variably at or near the summit of the chest; but, if intense, the sound is diffused, and it may be sometimes heard at a distance. Its diagnostic importance relates to the advanced stage of phthisis. The rale is heard chiefly or exclusively in the act of inspiration. It may be produced by the act of coughing sometimes with greater intensity than by respiration. 118 AUSCULTATION IN DISEASE. Pleural Rales — Friction-Sounds — Metallic Tinkling — Splashing. The signs embraced under the name pleural rales are, 1st. Sounds produced by the rubbing together of the pleural surfaces, and hence called friction-sounds ; 2d. Metallic tinkling; and 3d. Splashing or succussion sounds. Friction- Sounds. — Movements of the pleural surfaces upon each other take place in inspiration and expiration; but in health these movements occasion no sound. Sounds are produced when the surfaces are covered with a recent fibrinous exudation which prevents the normal continuous, unobstructed movements, and when the sur- faces are roughened with dense lymph or other morbid products. The sounds are generally interrupted, that is, two, three, or more sounds occur during the act of inspiration or expiration, or during both acts. The intensity of the sounds varies much in different cases. A slight grazing sound only may be heard, or, on the other hand, the sounds may be so loud as to be heard by the patient and by others at a distance. The character of the sounds is variable. The slight rubbing or grazing character may be imitated by placing over the ear the palmar surface of one hand, and moving over its dorsal surface slowly the pulpy portion of a finger of the other hand. In some instances, however, the rough character of the sounds is expressed by such terms as rasping, grating, and creaking. In these instances the sounds denote density of the morbid product which roughens the pleural surfaces. In connection with very rough sounds, vibration of the walls of the chest, or fremitus, is some- times perceived by palpation. Aside from the character of the sounds as just stated, FRICTION-SOUNDS. 119 they are distinguished by their apparent nearness to the car; they seem sometimes to be produced upon the sur- face of tlie chest. They are sometimes intensified by firm pressure of the stethoscope upon the chest. After a little practical knowledge of these sounds they can hardly be confounded with any other rales. Pleuritic friction-sounds generally denote pleurisy. In cases of pleurisy with effusion, slight rubbing or grazing is sometimes heard before much liquid accumu- lates within the pleuritic cavity. The physical condi- tions, however, after the effusion has been removed, are much morefavorable for the production of friction-sounds, and they are often now rough in character. They may be transient, or they may continue for a considerable period, their duration depending on the arrest of the movements of the pleural surfaces by means of either agglutination with lymph, or adhesion from the growth of areolar tissue. Pleuritic friction-sounds occur not infrequently in cases of pneumonia, denoting, in this connection, coex- isting pleurisy. Slight rubbing or grazing at the summit of the chest is one of the accessory signs of phthisis. It denotes a circumscribed, dry j)leurisy, which, as clinical experience show^s, is generally secondary to phthisis, and hence the diao-nostic sio;nificance of the siirn. In the foregoing instances in which friction-sounds are stated to occur, their significance relates to pleurisy. In some rare instances the sounds are produced by miliary tubercles or carcinomatous nodules projecting beyond the plane of the visceral pleural surface, without pleuritic inflammation. 120 AUSCULTATION IN DISEASE. Metallic TinhUng. — This is a vocal as, well as a re- spiratory sign. It is also produced by acts of coughing, and sometimes by the act of deglutition. The name ex- presses the distinctive character of the sign. It consists in a series of tinkling sounds of a high-f)itched, silvery, or metallic tone. The number of sounds varies from a single sound, to two, three, or more sounds, during an act of either iufspiration or expiration. Tins sign may be imitated in various way<«, by means of an india-rubber bag of considerable size. Forcing a liquid into the bag with Davidson's Syringe, tapping the bag with the finger, or shaking it, will produce tinkling sounds. The best mode of artificial representation of the sign is to connect the bag with a flexible tube, the latter containing a few drops of liquid, and blowing into the tube so as to pro- duce bubbles at the communication of the tube with the bag. In this latter experin)ent it is not necessary that the bag contain any liquid. It occurs irregularly, that is, it is not ])resent in every act of breathing, but is heard at variable intervals. It may sometimes be produced by forced, when it is not heard iu tranquil, breathing. It can only be confounded with tinkling sounds sometimes produced within the stomach. The latter, however, are easily discriminated by their situation, and the absence of associated signs denoting the affections of the chest in which the sign occurs. Metallic tinkling is the sign of pneumothorax with perforation of lung. In the great majority of the cases in which it is found, it is diagnostic of this aifection. It is, however, always associated with other physical signs corroborative of the diagnosis. It is a rare sign, in cases of phthisis, of a large pulmo- nary cavity, the conditions for its production being analo- INDETERMINATE RALES. 121 gous to those in pneiimo-hydrothorax, namely, a space of considerable size containing air, the space communicating with bronchial tubes. Splashing, or Succussion Sounds. — This sign is pro- duced by succussion, which is reckoned as one of the different modes of j)hysical exploration. Sounds thus produced are not infrequently heard at some distance; generally, however, succussion is practiced while the ear is a})plied to the chest, so that properly enough the sign may be embraced among the auscultatory signs, although not produced by respiration. Splashfng is pathognomonic of either pnenrao-liydro- thorax or pueumo-pyothorax. It is especially valuable as a sign of these affections because it is almost invariably available. The instances are extremely few in which the sign is wanting when air and liquid are contained in the pleural cavity. It is obtained by jerking the body of the patient with a quick, somewhat forcible movement, the ear being very near to, or in contact with, the chest. The sound is like that produced when a bottle par- tially filled with liquid is shaken. The sound is often high-pitched and amphoric in quality. The only liability to error is in confounding with this sign, splashing pro- duced within the stomach. Attention to other signs will always protect against this error. Indeterminate Bales. — Under this head may be em- braced some sounds sufficiently recognizable, but inde- terminate as regards the rationale of their production and the physical conditions which they represent. They may be designated crumplingand crackling sounds. The former are probably due to pleuritic rubbing, and the latter to the separation of some slightly adherent air- vesicles or bronchioles. Their diagnostic value relates 122 AUSCULTATION IN DISEASE. only to the early stage of phthisis. In conjunction with other signs, any indeterminate rale, if limited to the summit of the chest, and especially to one side, has some weight in the diagnosis. Crumpling and crackling sounds, however, are not uncommon in healthy persons at the end of forced inspiration. The fact of their presence at both summits, and the absence of other morbid signs, are the grounds for not considering them as evidence of dis- ease. They are found in health especially if the binau- ral stethoscope be employed. Their diagnostic signifi- cance, thus, depends on limitation to the summit of the chest on one side, and association with other signs point- ing to incipient phthisis. The Vocal Signs of Disease. The vocal signs of disease, with the exception of metallic tinkling, which is a vocal as well as respiratory sign, may all be considered as abnormal modifications of the normal vocal resonance and of the normal bronchial whisper. The student must, therefore, be familiar with the distinctive characters of these two normal signs before he is prepared to enter upon the study of the abnormal modifications {vide pages 77 and 82). He must bear in mind the facts which have been presented in relation to the normal vocal fremitus {vide page 77). The rules given for auscultation of the voice are also to be observed {vide page 7G). Embracing the abnormal modifications of the loud voice, the whisper and fremitus, the following are the signs to be considered: Bronchophony; Whis- pering Bronchophony ; ^Kgophony ; Increased Vocal Resonance; Increased Bronchial Whisper; Cavernous Whisper; Pectoriloquy; Amphoric Voice or Echo; Diminished and Suppressed Vocal Resonance; Dimin- BRONCHOPHONY, 123 ished and Suppressed Vocal Fremitus, and Metallic Tinkling. Bronchophony. Bronchophony has the same import as bronchial or tubular respiration. Like the latter sign, it represents complete or considerable solidification of lung. Gene- rally the two signs are associated, but either may be present without the other. The characters which are distinctive of bronchophony, as compared with the normal vocal resonance, are these: The vocal sound seems concentrated, in most cases near the ear, and the pitch is more or less raised. These characters are in contrast with the diffusion, distance, and lownessof pitch of the normal vocal resonance. The intensity of the sound is variable; it may be greater or less than the intensity of the normal resonance. A con- centrated, high-pitched sound, however feeble, is not less a sign of complete or considerable solidification of lung, that is, it is not less bronchophony, than when the sound is intense. Vocal fremitus is always to be discriminated from vocal resonance. The fremitus associated with broncho- phony may, or may not, be greater than the fremitus of health. Not infrequently the fremitus is less than in health. It is to be borne in mind that in some healthy persons bronchophony exists at the summit of the chest, espe- cially on the right side, over the primary bronchus. Existing alone in this situation, it may not be abnormal. Representing complete or considerable solidification of lung, this sign occurs in the different affections in which bronchial or tubular respiration has been seen to occur [vide page 9fS), namely, lobar pneumonia, phthisis, 124 AUSCULTATION IN DISEASE. chronic or fibroid pneumonia, condensation of lung from either pleuritic eifusion, the accumulation of air in the pleural cavity or the pressure of a tumor, collapse of pulmonary lobules, coagulation of blood within the air- vesicles, and carcinoma of lung. For the production of bronchophony, a less degree of solidification is requisite than for the production of bron- chial or tubular respiration. Hence, bronchophony may be associated with a broncho- vesicular, as well as with a purely bronchial respiration. This is illustrated in the resolving stage of pneumonia. When resolution has pro- gressed sufficiently for the bronchial to give place to the broncho- vesicular respiration, well-marked bronchophony is often found to continue, ceasing at a later period in the resolving stage. The apparent nearness to the ear of the vocal sound in bronchophony is wanting if a certain quantity of liquid intervene between the solidified lung and the w^alls of the chest at the situation auscultated. The voice under these conditions seems to be more or less distant. This difference is readily appreciated, ^¥ith this apparent distance of the bronchophonic voice, in some instances is associated the modification which is characteristic of another sign, namely, legophony. Whispering Bronchophony. The characters of this sign correspond to those of the expiratory sound in the bronchial or tubular respiration {vide page 93). The sound is more or less intensified, high in pitch and tubular in quality. If the patient pronounce numerals in a forced whisper, the characters are generally more marked than in the expiratory sound in forced breathing. The significance of this sign is the ^GOPHONY. 125 same as that of the bronchial or tubular respiration, and of bronchophony with the loud voice. JEgophony. This sign is a modification of bronchophony. As regards concentration and pitch, it has the characters of bronchophony, the distinctive features being apparent distance from the ear, and tremulousness or a bleating tone. From the latter the name is derived, the term signifying the cry of the goat. The characters which distinguish the sign from bronchophony are readily enough appreciated, and it represents a physical con- dition added to solidification of lung. This physical condition is the presence of liquid effusion. The sign is rarely present in cases of large effusion. It occurs usually when the chest is about half filled with liquid, and the lung at the level of the liquid is sufficiently con- densed to give rise to bronchophony. This condition, under these circumstances, involves agglutination of lung above the portion condensed by pressure. The sign also sometimes occurs in cases of pleuro-pneumonia, the solidification in these cases being due to pneumonic exudation. As a sign of liquid eifusion it possesses diagnostic value, although, owing to the fact that the existence of eifusion is easily determined by other signs, it may be said to be superfluous. When the person examined speaks with the teeth approximated, broncho- phony has somewhat of the character of liegophony. Increased Vocal Resonance and Fremitus. The distinctive character of this sign is an increase of the intensity of the resonance without notable change in other respects. The resonance may be more or less 11 126 AUSCULTATION IN DISEASE. intensified, but it is distant, diffused, and comparatively low in pitch ; in other words, the characters of broncho- phony are wanting. The differential points between bronchophony and increased resonance should be clearly apprehended, bearing in mind that the intensity of the sound in bronchophony may, or may not, be greater than the normal resonance. Increased vocal resonance occurs when the lung is solidified, the solidification not sufficient in degree to produce bronchophony. Lung slightly or moderately solidified gives rise to an increase of intensity ; if the solidification become considerable or complete, broncho- phony takes the place of the simple increase of intensity. Thus, at an early period in pneumonia, increased vocal resonance precedes bronchophony ; and in the stage of resolution the reverse of this takes place, namely, in- creased vocal resonance follows bronchophony, the lat- ter ceasing when resolution has progressed to a certain extent. Contrary to what would perhaps be anticipated in the instances just cited, the intensity of the sound when bronchophony is present may be not only not increased, but diminished below that of health ; that is, in the first stage of pneumonia the increased intensity may cease when bronchophony occurs, and return when broncho- phony disappears. Increase of the vocal resonance occure in connection with pulmonary cavities. Over a cavity of considerable size situated near the superficies of the lung, the vocal resonance is sometimes extremely intense without any bronchophonic characters. The latter, if present, denote considerable solidification either around the cavity, or between it and the walls of the chest. From the pres- INCREASED VOCAL RESONANCE AND FREMITUS. 127 ence or tlie absence of bronchoi)lionic characters with greatly increased intensity of resonance, the auscultator can judge whether the cavity be, or be not, in proximity to considerable solidification of Itmg. Irrespective of the cavernous stage of phthisis, the sign is of diagnostic importance in the different affections which involve moderate or slight solidification of lung, namely, pneumonia early in the disease and in the stage of resolution, phthisis, over the compressed lung in pleu- risy with moderate effusion, collapse of pulmonary lob- ules, hsemorrhagic infarctus, and carcinoma of lung. Into the diagnosis of all these affections, both bronchophony and increased vocal resonance enter; the former when solidification is considerable or complete, and the latter when it is slight or moderate. IncreavSed vocal resonance is especially valuable in the diagnosis of early or incipi- ent phthisis. An abnormal resonance, however slight, at the summit of the chest on one side, is an important sign in that affection. In determining an abnormal resonance on the right side, either at the summit or elsewhere, al- lowance must always be made for the normally greater resonance on this side. Increased vocal resonance has the same import as broncho- vesicular respiration. These two signs, how- ever, are not always in the same proportion ; that is, the characters of the latter maybe marked out of proportion to the amount of the increase of the vocal resonance, and vice versa. Increased vocal fremitus generally accompanies in- creased vocal resonance, and it denotes solidification of lung. Fremitus, however, and resonance are not always in equal proportion, that is, either may be increased more than the other. An increased fremitus is some- 128 AUSCULTATION IN DISEASE. times of value in the diagnosis of phthisis. The greater fremitus on the right side of the chest is always to be borne in mind, and due allowance is to be made for this disparity in determining that the fremitus is increased. Increased Bronchial Whisper. The significance of this sign is the same as that of increased vocal resonance and the broncho-vesicular respiration; it represents the same physical condition as the two latter signs, namely, solidification of lung, greater or less, but below the degree requisite to give rise to bronchophony and bronchial respiration. Its diagnostic application is, therefore, involved in the same pulmonary affections. The characters of the sign are those which belong to the expiratory sound in the broncho-vesicular respira- tion. They consist, therefore, of increase of intensity, a quality more or less tubular, and the pitch raised, these modifications of the normal expiratory sound varying in degree between the slightest appreciable morbid change and a close approximation to the bron- chophonic whisper. The modifications in degree cor- respond to the degree of solidification. To appreciate the characters of this sign, it must be studied in com- parison with those of the normal bronchial whisper in different portions of the chest. The most important of the diagnostic applications of the sign is in cases of phthisis in its early stage. In this application, the points of normal disparity between the two sides of the chest at the summit are to be borne in mind, and due allowance made for them {vide page 83). A greater intensity of the bronchial whisper at the right than at the left summit is not evidence of disease; PECTORILOQUY. 129 but greater intensity at the left summit is always abnor- mal. As a rule, the |)it('h of the normal bronchial whisper at the left, is higher than that at the right, summit; if, therefore, with a greater intensity of the whisper at the right summit, it be a matter of doubt whether it denote disease or not, when the pitch is higher at this summit, it is to be considered as morbid. Cavenioiis Whisper. — The characters distinctive of the cavernous whisper are those of the expiratory sound in the cavernous respiration, namely, lowness of pitch, and the quality blowing, that is, non-tubular. The in- tensity of the sound is variable. It is limited to a cir- cumscribed space corresponding to the situation and size of the cavity. Not infrequently the characters of the sign are brought into contrast with those of whispering bronchophony, or increased bronchial whisper, these latter signs existing in close proximity, and representing solidification of lung in the immediate neighborhood of the cavity. The diagnostic application of this sign is chiefly to advanced phthisis. Pectoriloquy. — In pectoriloquy, not merely the voice, but the speech, is transmitted through the chest; the auscultator recognizes words uttered by the patient. The student, however, must not expect to be able to carry on a conversation with the patient by means of the stethoscope. Often single words only can be recognized. To make sure that these are transmitted through the chest, care must be taken to exclude their direct trans- mission from the patient's mouth, and the auscultator should not know beforehand the words which are to be spoken. If these rules be not observed, the auscultator may err in supposing that the words are transmitted 130 AUSCULTATION IN DISEASE. through the chest. When auscultation is practiced with one ear, the other should be closed. Tiie speech with either the loud or the whispered voice may be transmitted, the latter, distinguished as whisper- ing pectoriloquy, being much more frequent than the former; moreover, in determining whispering pectorilo- quy, there is less liability to error in mistaking the per- ception of words coming directly from the mouth for the transmission through the chest. In the production of this sign, much depends on the distinctness with which words are articulated by the patient. Normal pectorilo- quy at the anterior superior portion of the chest is some- times observed. Pectoriloquy belongs among the cavernous signs ; but it is by no means exclusively the sign of a cavity; the speech may also be transmitted by solidified lung. It is easy to determine in any case whether the sign denotes a cavity or solidified lung. If, with transmitted speech, the voice have the characters of bronchophony, the sign represents solidification of lung; if, on the other hand, the characters of bronchophony be wanting, the sign represents a cavity. These statements apply equally to the loud and to the whispered voice. Of course, asso- ciated signs will be likely to show whether a cavity exists or not. It is to be added that a cavity and solidification of lung existing together, may conjointly be concerned in the production of the sign. Amphoric Voice or Echo. — This sign is identical in character with am])horic respiration, with which it is usually associated {vide page 100). The am])horic into- nation may accompany the loud voice and the whisper; generally, it is more appreciable or marked with the latter. Its significance is the same as that of amphoric DIMINISHED VOCAL RESONANCE. 131 respiration. As a rule, it rcj)rescnts the conditions in pnenmothorax, namely, a large space filled with air and perforation of hint^. In this affection it is associated with other signs which suffice for a prompt and positive diagnosis. It is not invariably fonnd in pneumothorax, and it may be present in a case at one time and wanting at another time, its production being dependent on the perforation being above the level of liquid, if the latter exist, and on the bronchial tubes leading to the perfo- ration being unobstructed. When not associated with other signs which are diagnostic of pnenmothorax, or pneumo-hydrothorax, it denotes a phthisical cavity of considerable size. It is not infrequently a sign of a phthisical cavity with rigid walls and communicating freely with bronchial tubes. It has this significance whenever pneumothorax can be excluded; and the asso- ciated signs in the latter affection are such that its ex- clusion is always practicable. The amphoric sound sometimes is observed to follow the oral voice; hence, the name amphoric echo. Diminished and Suppressed Vocal Resonance. — Diminution and suppression of the normal vocal reso- nance occur especially when the pleural cavity contains either liquid or air. Whenever the lungs are not in con- tact with the walls of the chest, the vocal resonance, as a rule, is either notably lessened or wanting:. The siartng.) ESMARCH (FRIEDRICH). EARLY AID IN INJURIES AND ACCIDENTS. In one small 12mo volume of 109 pages, with 24 illustrations. Cloth, 75 cents. (Just ready.) TiARQUHARSON (ROBERT). A GUIDE TO THERAPEUTICS. •L Third American edition, specially revised by the Author. Edited, with ad litions.embracingthe U S. Pharmacopoeia, by Frank Wood- bury. M. D. In one royal 12mo. volume of 624 pages. Cloth, $2 25. {Just ready.) fENWICK (SAMUEL). THE STUDENTS' GUIDE TO MEDICAL DIAGNOSIS. From the third revised and enlarged London edi- tiim. In oneroyjil 1 2mo. volume of 32S pages. Cloth, $2 25. FINLAYSON (JAMES). CLINICAL DIAGNOSIS. A Handbook for Students and Practitioners of Med;cine. In one handsoiue Svo. vol. of 540 pages, with 85 woodcuts. Cloth, $2 63. HENRY C. LEA'S SON & CO.'S PUBLICATIONS. 5 FLINT (AUSTIN). A TREATISE ON THE PRINCIPLES AND PRACTICE OF MEDICINE. Fifthedition, thoroughly revised ;in