COLUMBIA LIBRARIES OFFSITE I',/}' III '■ A MANUAL, OF burst open, discharging their contents. The brain runs out ; the soft parts have either become pulpy or have dis- appeared. The softened flesh falls away from the bones, the skeleton thereby becoming exposed. The sexes finally become undistinguishable, except in the case of the uterus being recognized, the last of the internal organs to putrefy. As a general rule, the order in which the internal organs putrefy is quite a regular one. Inferences from their con- dition as to the time elapsing since death are far more trustworthy, therefore, than those based upon an examina- tion of the body externally. The first part of the body to putrefy internally is the mucous membrane of the larynx and trachea, which becomes in color a dirty red, at the same time that the abdomen becomes greenish externally, as just described. The next organ to decompose is the brain of young infants. Then follow the stomach and intes- tines. In this connection it should be mentioned that the ordinary post-mortem redness of the mucous membrane of the stomach often resembles so closely that due to poison- ing, that the superficial examiner might be readily de- ceived, and attribute such a condition to poison having been taken. The spleen, omentum, and mesentery, and liver, if healthy at time of death, may resist putrefaction for several weeks. The brain in the adult, though a soft structure, does not usually putrefy before the fourth or fifth week. The next organs to putrefy are usually the heart and lungs. Then follow the kidneys, oesophagus, pancreas, diaphragm, and arteries. The last organ to de- compose is the uterus. In certain cases the uterus has been recognized even seven months after death. This fact is an important one, as we shall see hereafter in considering such questions as the possibility of a pregnancy having existed, of a foeticide having been committed, etc. MEDICAL JURISPRUDENCE AND TOXICOLOGY. ?>?> Conversion into Adipocere. — Under certain circumstances, a dead body, instead of undergoing putrefaction in the ordi- nary manner, is converted into the substance known as "adipocere," so called on account of its general resem- blance to a combination of fat and wax. 1 Adipocere, being chemically either ammonium or calcium stearate or oleate, is probably produced through the combination of a fatty acid of the fat with the ammonium resulting from the de- composition of the nitrogeneous tissues, the ammonium being often replaced afterwards by calcium. The forma- tion of adipocere being therefore a saponification, the presence of water, as might be expected, is e.ssential to its production. Dead bodies are, therefore, converted into adipocere only in graves containing water, or in wet or at least very moist soil. Inasmuch as dead bodies lying in water for any length of time may be converted into adipo- cere, it becomes a matter of importance to determine the length of time required for such conversion, since it will enable the medicaf examiner to state, in a general way at least, how long the body has been lying in the water when it was found. As the result of observations and experi- ments it may be said that, on the average, the body of a new-born child will be changed into adipocere after re- maining in water between five and six weeks. An adult body requires, for complete conversion into adipocere, one year if immersed in water, and three years or more if buried in wet earth. 2 Length of Time Elapsing since Death. — Having de- scribed in a general way the signs of death, there still 1 Fourcroy : Annates de Chimie, tome v., 1790, p. 154 ; tome vii. p. 17 ; Ohevreul : ibid., tome xcv. p. 5; Orfila et L&sueur: Tiuiie des Ex- humations juridiques, tome i., Paris, 18ol, p. 351; Schaueustein in Maschka, vol. iii. S. 445. 2 Devergie : Medecim legale, tome i., Paris, p. 97. 3 34 A MANUAL OF remains for consideration the question as to the medical examiner being enabled from such signs alone to deter- mine positively the length of time which has elapsed since death. That it is highly important that the medical examiner should be able to give such testimony has been well shown in cases of murder, such as those in which the defendant proved an alibi, but in which it was also proved by the medical testimony that the wounds causing the death were not inflicted during the period that the defend- ant claimed he was absent. It must be remembered, how- ever, notwithstanding the verdict of guilty in the cases just referred to, that any estimate as to the length of time elapsing since death based upon post-mortem examination alone can only be approximative. In a general way, therefore, it can only be stated in the case of the body being unburied and exposed to the atmosphere, that if the body is only slightly cold and the jaws beginning to stiffen, the eyes glazed and the eyeballs sunken, death has occurred within a period of from fifteen minutes to four hours. If, however, the entire body be cold and rigid, the abdomen has turned green and the odor of putrefaction is perceptible, the body is cold and pliant, and there is cadav- eric lividity, the rigor mortis having passed away, death has taken place within from one to three days in summer and from three to six days in winter. If greenish-brown stains and dark red lines are found extending more or less over a greenish-yellow body, together with relaxation of the sphincter ani muscle, then death has occurred within a period of from eight to ten days in summer, ten to twenty days in winter. If the entire body is green, the chest and abdomen enormously distended, if open blisters are found over the skin, and maggots in the muscles, the nails falling out, the color of the eyes unrecognizable, then MEDICAL JUEI8PRUDENCE AND TOXICOLOGY. 35 death has occurred within a period of from two to three weeks in summer, of from four to six weeks in winter. If the contents of the chest and abdomen have been dis- charged, some of the bones bare, the eyes enormously swollen, death has taken place within a period of from four to six months. Whatever be the remote cause of death in any particular instance, whether it be due to disease, injury, wounds, or fractures, it may be referred approxi- mately, at least, to an arrest of the action of the brain, heart, or lungs. In order to be able to determine the cause of death, the medical examiner should be familiar with the symptoms of death as due to the three causes just mentioned, together with the post-mortem appearance accompanying them. Symptoms and Post-mortem Appearances of Death from Diseases of the Brain, Heart, and Lungs. — The symptoms of death beginning at the brain, or coma, are stupor, insensibility to external impressions, loss of conscious- ness, slow, stertorous, irregular breathing; the respira- tion and circulation ceasing as the medulla becomes affected. The post-mortem appearances presented in the case of death beginning at the brain are effusion of blood into the cavities, due to apoplexy, rupture of the blood- vessels from fracture of the skull, embolism, abscess, con- gestion, and compression. Death beginning at the heart or syncope may be due to a deficiency in the quantity of the blood or anaemia ; or in the quality or asthenia. Death from anremia may be caused by rupture of an aneurism, or from a uterine hemorrhage, or from a division of a large vessel like the carotid artery. The symptoms of such con- ditions are paleness, lividity of lips, dimness of vision, vertigo, slow, fluttering, weak pulse, ringing in the ears, hallucination, with more or less delirium and nausea and 36 A MANUAL OF loss of brain power. On post-mortem examination the heart is usually found contracted and empty, especially if the latter is examined shortly after death. Death due to the asthenic condition occurs in fatty de- generation of the heart, in exhaustive diseases of any kind, starvation, and in poisuning from prussic acid. The symp- toms in such cases are cold hands and feet, lividity of lips, nose, and extremities, great muscular weakness, feeble pulse, senses and intelligence retained usually till the last. After death the heart is found contracted, or its cavities are dilated and flabby, and contain blood. Death beginning at the lungs, or asphyxia, is caused by mechanical obstacles, such as foreign bodies in the air- passages. Respiration may be arrested by spasm of the glottis, due to nervous excitement, or by paralysis of the respiratory muscles. The symptoms of a person dying from asphyxia are lividity of the face, great dyspnoea, vertigo, loss of consciousness, and convulsions. In death from asphyxia the venous system and the right side of the heart and lungs are found filled with dark blood. The left side of the heart and the arterial system, if rigor mortis has set in, are, however, usually found empty. Whatever may be the remote cause of death, the imme- diate cause is then to be looked for in the brain, heart, or lungs. A characteristic set of symptoms precedes death accompanied by characteristic post-mortem appearances in most cases. The medical examiner should be able, there- fore, to usually determine at the least the approximate cause of death. It sometimes happens, however, that notwith- standing that the symptoms are known, and that a most careful post-mortem examination has been made, the cause of death cannot be positively determined. Under such circumstances it may be supposed that there has been a MEDICAL JURISPRUDENCE AND TOXICOLOGY. o*7 sudden stoppage of the heart through reflex nervous in- hibition, as oecurs in persons who have drunk cold water when in an overheated condition, or as the result of sonic violent emotion. In such eases no post-mortem lesion of any kind may be found. It can only be said then that death may be supposed to have been due to some nervous influence. It is not worth while, however, for the medi- cal examiner to guess or speculate about the cause of death. The most prudent course to pursue, in reply to any ques- tions, is to admit that the cause of death cannot be stated. 38 " A MANUAL OF CHAPTER III. Manner of making Post-mortem Examinations in Medico-legal Cases — Identification of the Dead— Coroner's Inquest — Conduct of the Med- - ical Witness in Court. Autopsies. — In cases of sudden death, or death from violence, or death under suspicious circumstances, the coroner views the body, and if not satisfied as to the cause of death, directs his physician to make a post-mortem examination, the extent and thoroughness of which will depend entirely upon his discretion. It is essential that the results of the examination should be recorded at once in a book kept for that purpose, the examiner not waiting until he reaches his home, trusting to his memory for the facts. Neither should the record of the post-mortem ex- amination made in one book at the time be transferred later to another book, since the objection may be made that the two records are not the same. It is needless to add that the coroner's physician should have his name and address distinctly written in his note-book, so that in case it is lost, it may be advertised for, or the opportunity afforded for its return to its owner without delay. Before recording the results of the post-mortem ex- amination, the place, the year, the day of the month, and the hour of the day should be noted by the examiner. The deceased must then be identified from their own per- sonal knowledge, and not from hearsay, by two witnesses who knew the individual upon whom the post-mortem is to be made. 1 The height of the deceased should then be 1 The medico-legal questions as to the importance of the corpus delicti of proving that a death took place are well considered in Wharton and Stille: Medical Jurisprudence, 3 vols., fourth edition, Philadelphia, 1884, vol. iii. p. 613. MEDICAL JURISPKUDKNCE AND TOXK'ODifiV. 39 determined, the examiner being always provided for this purpose with a tape-measure. This may become an im- portant part of the testimony in certain cases, like that of murder, since it may be claimed that the deceased being a taller man, and presumably heavier and stronger than the defendant, the murder was committed in self- defence. The body of the deceased should, therefore, be weighed. In a properly-equipped morgue means are provided for this purpose. In their absence the weight of the body can at least be approximately estimated, and an idea can be obtained as to whether the deceased was strong, well-built, muscular, or weak, sickly, emaciated. The temperature of the body and surrounding atmosphere should be noted ; that of the morgue would usually be constant ; but if the post-mortem examination be made elsewhere — in a bar-room, in a yard, or in a field — the temperature would be variable, according to circumstances, season of the year, etc. If the medical examiner be called upon to make an examination of a dead body in the place where it was first found, it is very important that all the surroundings should be most carefully and critically ob- served. If the dead body be found in a room, for ex- ample, its condition should be noted as to the position of the tables, chairs, china — whether the room was in order or confusion, the latter being probably the state in the case of there having been a struggle. The floor, walls, doors, windows, and furniture should be carefully examined for blood-stains or stains of any kind, foot-marks. The con- dition of the clothing of the deceased should be noted as to whether it was cut or torn, etc. Indeed, no fact of any kind that could directly or indirectly aid in determining the cause of death, or lead to the arrest and conviction of 40 ' A MANUAL OF the murderer, if murder has been committed, should fail to be recognized and recorded by the medical examiner. A thorough examination having been made of the body externally, and the situation, extent, and nature of the external injuries having been noted, if any such be present, the body should next be examined internally. 1 Iu making the internal examination it is best to begin with the head, except in cases of asphyxia, as in such cases if the head is opened first the blood is apt to run out of the right side of the heart. The scalp haviug been divided, and the two parts everted, the skull, after it has carefully been ex- amined, should then be sawed through in such a manner that the calvaria 2 can securely be replaced. The dura mater, having been inspected, should then be divided and the condition of the arachnoid and pia mater be observed. The brain before removal should be examined as to con- gestion of its vessels, laceration of its substance, extravasa- tion of blood, etc. After removal of the braiu the base ot 1 Orth, Dr. Johannes : Compend of Diagnosis in Pathological Anatomy, with directions for making Post-mortem Examinations, translated by F. E. Shattuck, M. D., and G. K. Sabine, M. D., New York, 1878 ; Virchow, Professor Rudolph : Post-mortem Examinations ivith especial reference to Medico-legal Practice, translated by J. P. Smith, M. D., Philadelphia, 1880; Casper: op. cit., vol. i. p. 87. 2 The word calvarium, often used synonymously with calvaria, does not appear, so far as known to the writer, to have been made use of by Latin authors. The neuter plural calvaria was used, however — for ex- ample, by Ennius in his description of certain marine animals: "Poly- pus Corcyrse, Calvaria purgina acarnse, Purpura, Muriculi, Murex. dulces quoque echini'' (Enniarixe Poesis Beliquim, Lipseae, 1854, p. 167). The acarnse mentioned by Ennius are probably the fish referred to under that name by Aristotle and Pliny — the Pagellus acharne of Cuvier. Apuleius also uses the word calvaria, not, apparently, in the same sense in which that word is used by Ennius as parts of the Acarne, but as if the calvaria were distinct animals, the latter being referred to as "Marina calvaria" (L. Apuleii, Opera Omnia, Lipsea?, 1842, pp. 520, 531). MEDICAL JURISPRUDENCE AND TOXICOLOGY. 41 the skull should be carefully examined for fractures. The condition of the brain should be noted as to its consistence, color, the existence of tumors, abscesses. The spinal column should next be opened through its whole extent, and the cord removed, and its condition noted. The thorax and abdomen should then be opened by making an incision extending from the root of the neck to the pubes, dividing the cartilages of the ribs, and the sterno-clavicular liga- ments, and reflecting the sternum. The heart and lungs, larynx and trachea should be at once examined in situ, and after removal, parts of the organ being preserved. The stomach having been ligated at both the cardiac and pyloric orifices, each orifice being secured by two ligatures, should then be removed by cutting between the two ligatures at each orifice, and placed in a clean glass jar. The intestines should be removed and preserved in a similar manner, though separately from the stomach. The condition of the liver, spleen, pancreas, kidneys, and uro-genital apparatus should be noted and portions of the organs preserved for microscopic examination if necessary. WEIGHTS OF ORGANS OF ADULTS. 1 Heart, male 11 oz. " female 9 " Brain, male 49J " " female ' . . . 44 " Spinal cord 1-lf " Liver 50-60 " Pancreas 2J-3J " Spleen 5-7 " Lungs (together), male 45 " Lungs (together), female 32 " Thyroid body 1-2 " Thymus at birth £ " Kidneys (together) 9 " 1 Woodman and Tidy : A Handy-Book of Forensic Medicine, etc., p. 11. 42 A MANUAL OF Weights of Organs of Adults— Continued. Suprarenal capsules 2 dr. Prostate gland 6 Testicles (together) f-1 oz. Unimpregnated uterus • 7-12 dr. The post-mortem examination having been concluded, the calvaria should be replaced in position, the parts of the scalp inverted, and the latter as well as the abdominal walls brought together and securely sewed. 1 Identification. — Ordinarily the dead body submitted for medical examination is either entire or almost so. Not infrequently, however, the body has been purposely muti- lated after death, by a murderer, for example, with the view of escaping detection, or as in cases of death from fire, explosions, railroad accidents. Under such circum- stances, when often only parts of the body or bodies can be recovered for examination, the highest anatomical skill may be requisite for the identification of the remains or the determination of the cause of death. But little diffi- culty, however, should be experienced in determining, for example, whether the bones recovered be human or not, if the greater part of the skeleton, especially if parts of the skull, be submitted for examination. It is only when a bone or a fragment of a bone has been obtained, as from the ruins of a fire, that mistakes as to their true nature are likely to be made by the medical examiner. Inas- much as the bones of the domestic animals have been 1 In this connection it should be mentioned that in cases involving life or death the post-mortem examination should be thorough, lest the defence urge that the true cause of death be other than that alleged. In more than one case through such neglect has the prosecution failed to convict, owing to some organ not having been examined (Taylor, Alfred Swayne : Manual of Medical Jurisprudence, eleventh American edition, by Clark Bell, Esq., Philadelphia, 1892, p. 23). MEDICAL .TURISPKITDENCB AND TOXICOLOGY. 43 frequently mistaken for those of man, even by physicians, if the examiner be in doubt as to the nature of a hone, it would be better for him to submit it to a comparative osteologist for determination, rather than to trust to his own judgment, unless specially qualified by previous osteo- logical studies to give an opinion on the subject. As regards the skull more especially, there is usually no difficulty in determining whether a skull be a human one. The particular race, however, cannot always be indicated, for while there is no difficulty, for example, in distinguish- ing a Caucasian skull (Fig. 1) from that of a typical negro Fig. 1. Fig. 2. The facial angle of Camper; in European crania usually it does not exceed 80° (a, b, c, d, lines forming the facial angle). Facial angle of Camper; in the Ne- gro about 70° (a, b, c, d, lines forming the facial angle). (Fig. 2), it is not only difficult, but often impossible to exactly identify the many forms of skull intermediate in character between the two. In the identification of human remains the sex, age, and stature are usually to be deter- mined. Inasmuch as the skeleton of the male differs from that of the female as regards the size, weight, strength of the bones, in the relative development of the ridges and promi- nences serving for the attachment of the muscles, and more particularly in the size and shape of the pelvis (Figs. 3, 4), all of which peculiarities are fully described in works on anatomy, there is usually no difficulty if the skeleton is 44 A MANUAL OF entire in determining whether it be that of a male or a female. If, however, a single bone or a fragment of a bone be sub- Fig. 3. Fig. 4. Male pelvis. Female pelvis. mitted for an examination it is often so difficult to deter- mine the sex that no positive opinion should be expressed. The age of a body can be approximately at least in- ferred from the development of the teeth and the extent of the ossification of the bones. It is important, there- fore, that the medical examiner should be familiar with the period and order in which the teeth appear and the bones ossify. In the jaw r s of a child at full term there are usually found the rudiments of twenty primary and four secondary or permanent teeth, twenty-four teeth in all. The average date of the eruption or cutting of the primary or milk teeth is as follows : The four central in- cisors appear from five to eight months after birth, the four lateral incisors from seven to ten months, the four anterior molars from twelve to sixteen months, the four canines from fourteen to twenty months, and the four pos- terior molars from eighteen months to three years. 1 At a period of life varying between six and seven years the 1 Bell, T. : Anatomy, Physiology, and Diseases of the Teeth, 1837, pp. 66, 79. MEDICAL JURISPRUDENCE AND TOXICOLOGY. 45 jaws contain forty-eight teeth — twenty milk teeth and twenty-eight permanent teeth situated behind the milk teeth, which they will replace as the former are shed. The order in which the permanent teeth appear is as fol- lows : The four anterior molars appear at seven years, the four central incisors at eight years, the four lateral incisors at nine years, the four anterior premolars at ten years, the four posterior premolars at eleven years, the four canines at about twelve years, the four second molars at about fourteen years, 1 the four posterior molars at from eighteen to twenty-one years of age. As a general rule, the teeth of the lower jaw appear first, but in this respect there are exceptions, as also in the order of the appearance of the teeth. It should be mentioned in this connection, also, that in cases of rickets the cutting of teeth is often delayed, while in syphilis it is premature. 2 In the latter case the teeth have a notched appearance, and often crumble away. With the loss of the teeth and progressive absorp- tion of the alveolar processes due to age, the lower jaw undergoes a marked change in the widening of the angle of its neck, and in the diminution of the width of its body, imparting to the mouth that expression so characteristic of the aged. The degree of ossification of the lower epiphysis of the femur (Fig. 5) is one of the most certain signs of the age of the foetus and of the new-born child. 3 Thus if no os- sific deposit be found in the cartilaginous epiphysis of the 1 Saunders, Edwin : " The Teeth a Test of Age, considered with Refer- ence to the Factory Children/' addressed to the members of both houses of Parliament, London, 1837, p. 42. 2 Woodman and Tidy : Handy Book of Forensic Medicine and Toxi- cology, London, 1877, p. 623. 3 Beclard : Xmtrclle Journal dc Mrderine, Chirvrgie el Pharmaeie, tome iv., 1819, p. 113; Casper: op. cit., vol. iii. p. 23. 46 A MANUAL OF femur it may be stated that the foetus has not yet reached the eighth month of intrauterine life. If the ossific deposit has attained a diameter of about one line the foetus has reached full term. If the ossific deposit measures more Fig. 6. Fig. 5. From a child at birth, showing a nucleus in the lower epiphysis. The natural skeleton of a child about two years old. than one-quarter of au inch the child has lived after birth for some little time. The length of the skeleton of the child at birth is usually about sixteen inches. Ossification begins at the extremities of most of the long MEDICAL JUKISPBUDENCE AND TOXICOLOGY. 47 bones at the end of the first year, and progresses from that time on until ossification is completed. The epiphyses <>l all the long bones are usually found united to their shafts in the male at about twenty-four years, in the female at about twenty-two years. After ossification has once been completed it is extremely difficult, if possible, to deter- mine exactly the age from an examination of the skeleton Fig. 7. Sternum. Sacrum. (Anterior surface.) alone. It may be mentioned, however, that the bones of the sternum (Fig. 7) are usually found ununited until after forty, 1 those of the sacrum (Fig. 8) and os coccygis until sixty years of age. The height of a body may be 1 Guy and Ferrier: Principles of Forensic Medicine, London, 1881, p. 36 ; Wharton and Stille : Medical Jurisprudence, 3 vols., fourth edition, Philadelphia, 1884, voh iii. p. 470, 48 A MANUAL OF approximately estimated from the skeleton, the latter being entire, by placing the bones in position and adding from one inch and a half to two inches to the length to supply the missing soft parts. In the absence of the skull there should be added about ten inches to the height of the spine of the seventh cervical vertebras from the ground. A skeleton may be identified as that of some particular person many years even after death through the presence of deformities, fractures, callus, etc. The production of callus is the result of the reparative process that takes place in the case of fractured bones, and its presence proves that some time must have elapsed between the time of fracture and death. The absence of such callus in cases of death following fractures would clearly indicate that death fol- lowed soon after the injury causing the fracture, and that in the case of fracture of the skull the injury was the cause of death. Under certain circumstances it may become a matter of importance to determine from an examination of the skeleton alone the length of time that the body has been buried. It may be said that ordinarily within ten years after burial the soft parts of a body entirely disap- pear; the bones, however, may resist decomposition for thirty or forty years, particularly if the surrounding soil is dry. It is well known, however, that the skeletons of individuals buried in leaden or in stone coffins have been found in a tolerable state of preservation even after a lapse of more than a thousand years. Medical Witnesses at the Inquest. — After the coroner has held his inquest, and the coroner's physician and the witnesses have given their testimony, and the jury sub- mitted their verdict, the defendant, in case of the verdict being guilty, is then remanded to the district attorney's office. The case then comes up before the grand jury, to MEDICAL JURISPRUDENCE AND TOXICOLOGY. 49 which the coroner's physician slates substantially what he has already said at the coroner's inquest. If the grand jury finds a true bill the case then goes to court; the trial is set for a certain day, is finally held, and the coroner's physician is subpoenaed for the third time to appear in court. If the court is aware that the coroner's physician or any of the medical experts engaged in the case have large practice or are connected as lecturers with any particular medical schools, etc., it is very considerate, as a general rule, arranging its business so as to inconvenience them as little as possible. It is incumbent, however, upon the physician, whether he be the coroner's physician or retained as an expert for the defence, to treat the court with every possible respect, to be always punctual in attendance, and if he be unavoidably delayed by professional exigencies, to send the court word explaining the cause of non-attend- ance. The court, however, will not submit to any of the physicians subpoenaed straggling in at any hour of the day with no excuse to offer for their non-attendance but de- tention by their every-day practice. Conduct of Medical Witnesses in Court. — At the trial, the medical witness, if he be the coroner's physician, is examined first by the prosecution, by the district attorney. Having given testimony, he is cross-examined by the counsel for the defence, and is then usually re-examined by the district attorney, and here as a rule, the ex- amination ends. In giving evidence in court, the medi- cal witness should always maintain a dignified, composed demeanor. He should never be arrogant or show any irritability, still less lose his temper, however much he may be annoyed by the examination or cross-examina- tion. He should never forget that the object of the 4 50 A MANUAL OF prosecution is to elicit all the evidence that will lead to conviction ; the object of the defence to try to rebut, break down all that the prosecution hopes to establish. The medical witness should so answer that he can be heard by the whole court, addressing himself more particularly to the jury. His answers should be brief and given in the simplest language, all technical terms being avoided as much as possible. Finally, the medical witness should never be ashamed of saying in open court that he does not know. The court does not expect the medical witness to know everything. Nothing is more foolish for a witness than to hazard a guess in answer to a question for fear of being thought ignorant. Dying declarations, it may be mentioned in this con- nection, are accepted in law as evidence without being sworn to. It is naturally presumed that all statements made at such a solemn crisis must be sincere, believed at least to be true by the dying person even if subsequently shown not to be so. The attending physician under such circumstances having expressed the opinion that the patient is dying and in sound mind, a magistrate should be sum- moned to take down any statements that the dying person may wish to make. Should it not be possible to obtain the services of a magistrate, then the attending physician can take down the dying declarations. The physician should, however, limit himself to writing down the exact words of the dying person without offering any interpre- tation whatever. The statement should be read over to the dying person and if possible his signature to it obtained. MEDICAL JUKLSritUDENCE ANJ) TOXICOLOGY. 51 CHAPTER IV. Medico-legal Definition of Wounds — Comparison of Wounds with Weapon inflicting them and Clothes of Deceased — Incised, Contused, Penetrating Wounds — Suicidal, Homicidal, Accidental Wounds — Gunshot Wounds — Causes of Death from Wounds. Medico-Legal Definition of Wounds. — A wound, from a purely surgical point of view, is regarded as a solution of continuity of the soft parts occasioned by external vio- lence. The medico-legal idea of a wound is, however, far more comprehensive, embracing all injuries of the body, external or internal, with or without a solution of continuity of the skin, produced suddenly by external violence. 1 As the danger of a wound will depend on the age and constitution of the person, its position, the weapon by which it was inflicted, the amount of hemor- rhage, and numerous other circumstances, it is impossible for a physician to state positively whether a wound will prove fatal or not. Wounds at first apparently trivial have subsequently, in many cases, as is well known, been the cause of death. The medical witness should, therefore, express himself most cautiously if he replies at all to the questions so often asked, " Will such a wound prove fatal?" " Was such a wound necessarily mortal ?" In making a post-mortem examination in cases where death is due to wounds, it is most important that the medical examiner should satisfy himself, not only that the wound was the cause of death, but also that the remainino; organs were healthy, or at least were not in such a condi- tion that death could be attributed in any way to them, or 1 Beck, T. B. and J. B. : Elements of Medical Jurisprudence, eleventh edition, Philadelphia, 1860, p. 282. 52 A MANUAL OF to any other cause than the one assigned. On more than one occasion has the defendant been acquitted owing to such neglect, giving rise in the minds of the jury to the doubt as to whether disease or the wound was the real cause of death. On the other hand, as in a celebrated case, the defendant would have been convicted of murder, it being in evidence that the deceased, a young girl, had received from him a severe beating, had not the true cause of death, the poison taken, been well established by the medical examination. 1 In cases of death from wounds the medical examiner should carefully note their exact situation, direction, and Fig. 9. 'V' ". ~yi m Human hair. 1. The hair of a child. 2. Hair of an adult. 3. Pointed ex- tremity of the hair of the eyebrow. a. Transverse section of the hair showing the cortical and medullary portion, and air-cells in the centre of the cylinder. Human hair with the tubu- lar sheath as torn out by force. extent. If the weapon by which the wounds were known or supposed to have been inflicted has been obtained, it 1 Wharton and Stille: op. cit., vol. iii. p. 216. MEDICAL JURISPRUDENCE AND TOXICOLOGY 53 should bo compared by the medical examiner with the wounds themselves, so that, on subsequent examination, he can positively state whether such wounds as were found could have been inHicted by the weapon submitted. The clothes of the deceased should be carefully inspected, and any rents, cuts, or tears found compared with the wounds in the body and with the weapon by which they were in- Fig. 10. Fig. 11. Microscopic appearance of hairs of various animals. 1. Hair of the span- iel. 2. Hair or fur of the rabbit. 3. Hair of the hare. 4. Hair of the horse. 5. Hair of the goat. 6. Hair of the fox. 7. Hair of the cow. 8, Hair of the fallow deer. 1. Cotton.— a. normal condition: b, portion treated with sulphuric acid and iodine; c, fragment of gun-cotton. 2. Flax— a, normal fibre ; 6, portion boiled with nitric acid ; c, treated with nitric acid, and afterwards with sul- phuric acid and iodine. flicted. Hairs and fibres found upon the weapon supposed to have inflicted the fatal wound, or upon the person of 54 A MANUAL OF the accused, should be examined with the microscope and compared with those of the clothing worn by the deceased. As a general rule, human hairs (Fig. 9) can readily be distinguished from those of animals, or from fibres of cotton, silk, wool, etc. The hairs of the lower animals, some of which are represented in Figure 10, differ in many respects from those of man, being generally coarser, thicker, shorter, and less transparent. Microscopically, the most striking differences in hairs are presented by the cells and linear markings of their cortical portions. The fibres of cotton (Fig. 11, l) are flattened bands disposed in a spiral or twisted manner. Those of linen (Fig. 11, 2) are rectili- near, tapering to a point and presenting pointed markings at unequal distances. Silk fibres are cylindrical in shape, almost entirely free from markings, and refract light power- fully. The fibres of wool are rather irregular in form and unequal in thickness. The importance of making a thorough post-mortem ex- amination in cases of death from violence is well shown in cases of persons crushed to death, as by a heavily-loaded wagon. 1 It is well known that, although the external signs of violence in such cases may be limited to a few abrasions, the internal injuries causing death may be of the most ex- tensive and serious character. Character of Wounds. — Wounds are usually described as being incised, lacerated, contused, punctured, or pene- trating. Incised wounds may generally be recognized by the regularity and evenness of the cut; and it might natu- rally be supposed that they would be made by cutting weapons, penetrating wounds being supposed to be inflicted by pointed instruments, and contused wounds by blunt ones. It must be admitted, however, that in certain cases, as in 1 Casper : op. cit., vol. i. p. 112, case xl. MEDICAL JURISPRUDENCE AND TOXICOLOGY. 55 wounds inflicted by broken glass or china, which resemble exactly incised wounds, it might be very difficult to Bay how the wounds had been made. Indeed, it is impossible for the medical examiner, though often asked, to state positively whether a wound was inflicted with a particular kind of weapon. Suicidal Wounds. — It often becomes important to deter- mine whether a wound was inflicted before or after death. In the case of an incised wound this is not very difficult, since, if made before' death, the edges of the wound are everted and are more or less filled with coagulated blood, principally of an arterial character, or with granulations, pus, or sloughs, if any length of time has elapsed before death. Contused wounds, if made during life, are char- acterized by ecchymoses, suggillation, or the black-and- blue discoloration due to the rupture of small vessels, and the effusion of blood into the cellular tissue under the skin. The progressive changes of color — purple, black, violet, green, yellow — exhibited by ecchymoses serve not only to indicate whether the bruise was made before or' after death, but also as to the length of time elapsing since its production. Thus, for example, within twelve hours after the injury, and in some cases immediately afterward, the color presented by the bruise is that of a purplish-black ; by the third day it has become violet ; by the fifth or sixth day, green ; and by from the eighth to the tenth day, yellow. The latter color grad- ually disappears by from the twelfth to the fourteenth day, the skin reassuming its natural hue and presenting no trace of the discoloration. The situation, extent, and direction of a w T ound and the position in which the weapon was found should most carefully be observed and noted by the medical examiner, as it may become 56 A MANUAL OF essential under certain circumstances to determine whether the wound was suicidal, homicidal, or accidental. 1 In cases of persons taking their own lives, the mouth, fore- head, the region over the heart, etc., are usually chosen if fire-arms were used ; the throat or heart if the wounds were inflicted with cutting instruments. While ordinarily accessible parts of the body are selected by suicides, it must not be forgotten that insane persons, in committing suicide, have inflicted wounds upon themselves in most in- accessible parts, such as the back of the head and neck. It is well known that insane persons have killed them- selves by falling backwards, their heads striking upon some hard substances, or by shooting themselves through the back of the head. The fact of a person being found dead shot through the back of the ear might suggest that the wound was homicidal. It would not, however, prove it ; since it is well known that insane persons have taken their lives in that very way. Incised wounds of the throat, es- pecially if the direction of the wound be from left to right, the deceased being right-handed, are usually regarded as presumptive of the death being suicidal. Homicidal Wounds. — It should be remembered that a very common way of committing murder is by cutting the throat of the victim, the murderer standing behind ; a wound inflicted in such a manner would resemble that committed by a suicide. On the other hand, the irregu- larity of the wound often observed in such cases, and sometimes submitted as a proof that the wound was homi- cidal, and attributable to the resistance offered by the deceased in his struggle for life, might just as well be ac- counted for on the supposition that it was suicidal and due 1 Casper : Gerichtliche Leichen CEffnungen, Erstes Hundert, Berlin, 1853, S. 17. MEDICAL JURISPRUDENCE AND TOXICOLOGY. 57 to the nervousness and indecision of the deceased. A homicidal can usually be distinguished from a suicidal wound by its direction. Tims, for example, if a man were found dead with a wound in the neck of such a char- acter that it could be positively stated that the weapon had been partially turned and withdrawn, and again plunged into the neck in a different direction, as is sometimes done by German butchers, 1 the proof would be strong of the wound being homicidal. Or, if the nature of the wound in the neck indicated that it had been made by cutting from within outward, as is often done by English butchers in the killing of sheep, it would be strong presumptive evidence that murder had been committed. Accidental wounds are usually found in such parts of the body as are exposed. If wounds, the nature of which might otherwise lead to the supposition that they had been made accidentally, are found upon both sides of the body, the presumption would then be that they were homicidal. Gunshot wounds are essentially contusions. Owing, however, to the vitality of the parts struck being destroyed by the projectile, there ensues a process of sloughing. In this respect gunshot wounds differ from ordinary wounds. They differ very much in appearance, according to the nature of the projectile, to the distance from which the piece was discharged, etc. As a general rule the hemor- rhage following a gunshot wound is not very great, unless some of the large vessels are wounded. It should be mentioned, however, that though the external hemorrhage may not be very great, owing to the form and size of the wound, the internal hemorrhage may be so severe as to prove fatal. If the weapon be in close proximity to the 1 Kopp's Jakrbucher, Erster Jahrgang, 180S, S. 143. 58 A MANUAL OF body at the moment that it was discharged, the wound made is large, the skin is denuded, blackened, and partly burned. The hair or the clothes are also usually scorched. The orifice of entrance of the missile, if it be a ball, is depressed and larger than that of the exit orifice. 1 The character of the entrance orifice of the wound will depend upon the shape of the missile, the velocity with which it was travelling, and the distance from which it was fired. Thus, a wound made by a conoidal ball, like that of a minie rifle, is linear in form. Such a wound produces but little external, though considerable internal, injury. On the other hand, the wound made by a rifle ball is ragged and large. A ball after entering the body may, as is well known, be so deflected from its course by striking a bone or a tendon, etc., as to pass entirely around the body and so reach finally the point of entrance. If a gunshot wound be caused by a load of shot, the appearance presented will depend upon the distance from which the shot was fired. If the weapon discharged be within twelve inches of the body, the wound will usually be a single one. Beyond that distance each shot will make a single individual wound. 2 It should be mentioned that a single shot might cause death, as in the case of the wounding of the aorta. Serious, if not fatal, wounds may be caused by wadding and gunpowder alone if the weapon be within three or four inches of the body. Causes of Death from Wounds. — With reference to the committing of suicide by means of fire-arms, it may be mentioned that in fully four- fifths of the cases reported 1 According to some authorities, the exit is larger than the entrance orifice (compare Casper, vol. i. p. 266; Woodman and Tidy, p. 1115; Wharton and Stille, vol. iii. p. 234). 2 Lachese : Annates de Hygiene publique, Paris, 1836, p. 359; Casper: op. cit., vol. i. p. 266. MEDICAL JURISPRUDENCE AND TOXICOLOGY. ■>■> the part of the body selected for the infliction <>f tlic wounds was the head, the mouth being the part more par- ticularly chosen. 1 Under certain circumstances it may become important for the medical examiner to be able to state, in the case of death from wounds, the real cause of Fig. 12. Imaginary lines drawn upon the surface of the abdomen, dividing it into regions. These were, no doubt, devised by reason of the absence of any charac- teristic eminences or depressions upon this extensive surface, principally attrib- utable to the absence of any skeleton, osseous or cartilaginous. 1. Right hypo- chondriac region. 2. Epigastric. 3. Left hypochondriac. 4. Right lumbar. 5. Umbilical. G. Left lumbar. 7. Right iliac. S. Hypogastric. 9. Left iliac. death, whether immediate or remote. The immediate cause of death from a wound is either hemorrhage or shock, the latter being the result of a powerful impression made upon the nervous ceutres. Of the remote causes of death from wounds the most common are tetanus or 1 De Boismont : Du Suicide, deuxieme edition, Paris, 1865, p. 681. 60 A MANUAL OF lock-jaw, erysipelas, hospital gangrene, surgical opera- tions, including the use of ether or chloroform. The danger of wounds depends, to a great extent, upon the parts of the body affected. Thus scalp wounds are not usually dangerous unless followed by erysipelas. It should be remembered, however, in cases of wounds of the head, that a fracture or effusion of blood upon the brain, or con- cussion, may be produced by a blow, even though the scalp be uninjured. It is most important that the effects of concussion should not be mistaken for those of intoxica- tion. Unfortunately in too many instances persons arrested upon the charge of intoxication have died in station-houses from concussion of the brain, when their lives might have been saved had medical attendance been summoned. Wounds of the face are not usually dangerous unless the orbit be involved, as in penetration of the orbital plate by the point of an umbrella thrust into the face. The danger of wounds of the neck is due to the presence of the great vessels, the division of which, in case of the throat, gives rise to severe hemorrhage. The trachea and larynx may be divided, however, without necessarily proving fatal, unless the blood flows into the trachea in such quantity as to cause death. Death from wounds of the chest is usually due to hemorrhage from the heart, lungs, or great vessels. In cases of wounds of the abdomen, involving the liver, stomach, or intestines (Fig. 12, 1 , 2, 3), the cause of death is frequently peritonitis. With regard to wounds of the blad- der (Fig. 12, 8) it must be borne in mind that, if distended, it may readily be ruptured by a blow upon the abdomen, the cause of death being usually peritonitis. Frequently, however, under such circumstances, there may be no signs of external injury. In wounds of the spine the danger is proportional to the extent to which the spinal cord is in- MEDICAL JDE18PRUDENCB AND TOXICOLOGY. 61 volved, death taking place instantaneously if the medulla or upper portion of the spinal cord be wounded. The danger in wounds of the generative organs is due to the severe hemorrhage which usually ensues. In the male sex, in the case of the insane, castration and amputation of the penis arc frequently self-inflicted. 62 A MANUAL OF CHAPTER V. Blood-stains — Chemical, Microscopical, Spectroscopical Methods of Investigation — Coagulation of Blood — Conditions Influencing Coag- ulation. Not unfrequently, in cases of murder, it becomes necessary to determine if certain dark stains, such as are found on a knife, linen, underwear, pieces of wood, etc., were made by blood. The appearance presented by blood- stains will vary according to their size, shape, and color. Usually the stain consists of distinct spots ; it may, how- ever, be a mere streak or film. The color of recent blood- stains is red, that of old ones brown or brownish-red. It will be more or less modified according to the nature of the material upon which the blood has fallen. Thus the color of blood upon soft wood, linen, or cloth is dark ; that upon a polished metallic surface is shining, the spots presenting in the latter case cracks radiating from the centre. There are three methods of examining stains supposed to have been made by blood, the chemical, the microscopical, the spec- troscopical, all of which, on account of the importance of the subject, merit at least a brief description. The chemical method of investigation is based upon the fact that the haemoglobin of the blood is soluble in cold water. If the suspected blood-stain is in sufficient quan- tity and not so old that the haemoglobin has been con- verted into hsematiu, by proper manipulation a solution MEDICAL JUEISPEUDENCE AND TOXICOLOGY. 63 of the coloring matter of the blood can be obtained and then tested. If the article stained be a linen shirt, for example, a small piece should be cut out and suspended in a test-tube containing cold distilled water. In a few minutes, or longer, if the stain be an old one, the color- ing matter of the blood will pass into the water, color- ing it red. If the stained material to be examined is attached to wood or a knife-blade, it must be scraped or cut off and then soaked in water. Should the solu- tion be not complete, a trace of citric acid or a little ammonia may be added, the latter not affecting the color of the solution. The solution so obtained should then be heated in a test-tube over a spirit-lamp. If the solu- tion be that of the coloring matter of the blood, it will coagulate, the red color will disappear, and a brownish- green material will be precipitated. In this way a solution of the coloring matter of the blood may usually be dis- tinguished from other red solutions, such as those of red prints, logwood, kino, madder, cochineal, which do not coagulate when heated, and which change their color when ammonia is added. Stains made by red paint or by lemon-juice on iron, while slightly resembling blood-stains, can be distinguished from the latter through their color becoming a bluish, inky black on addition of tincture of galls, ferro-cyanide of potassium, or by other tests for iron. Another test for blood, that known as the guaiacum test, is based upon the fact that the resin of guaiacum when oxidized assumes a sapphire-blue color, and that this change in the color of the resin can be induced by the addition of blood and per- oxide of hydrogen together, but not by the addition of blood alone. A convenient way of applying the guaiacum 64 A MANUAL OF test, frequently made use of by the writer, is to add a few- drops of a freshly-prepared tincture of guaiacum to a small quantity of water, by which the resin is precipitated. The water holding the resin in suspension is then divided into three portions. To the first portion a few drops of peroxide of hydrogen dissolved in ether are added ; to the second portion a few drops of the solution supposed to con- tain the coloring matter of the blood. In neither case will any change in the color of the resin be observed. Now to the third portion add a few drops of the suspected solution and of the etherized peroxide, and at once the resin will assume a sapphire-blue color. Should the solution be turbid through excess of the resin, a few drops of alcohol will instantly clear it. It should be mentioned in this connection that the resin of guaiacum in the presence of peroxide of hydrogen is oxidized, turns blue by the ad- dition of bile, saliva, red wine, as well as by blood. The color of bile and saliva, however, should serve to dis- tinguish these secretions from blood, while in the case of red wine several hours are required to produce the blue color in the resin. It will be observed that the existence of blood is not directly proved by the chemical tests just described, but is inferred from the presence of its coloring matter or haemoglobin, and in most cases is only pre- sumptively established. The microscopic method of proving the existence of blood depends on the ability of the examiner to treat the material submitted to him in such a way that if it be blood the corpuscles, and more especially the red ones, may be sufficiently restored to admit of identification under the microscope, or at least to enable him to obtain the crystalline forms developed through changes in their coloring matter. The separation of the corpuscles from a MEDICAL JUIUSI'KUDKNCK AND TOXICOLOGY. GO material consisting of pieces of linen, wood, or iron stained witli blood mixed with dirt, etc., is a far more difficult operation, however, than that of demonstrating simply the presence of blood-crystals. If the material submitted for examination is a piece of linen, for example, stained with what is supposed to be blood, a piece of it should be cut out and. placed upon a clean glass slide and moistened with Fig. 13. © ^ Blood-Corpuscles (X 450). a solution consisting of one part of glycerine to seven of water, or with a solution of common salt having a specific gravity of that of the serum of the blood. The specimen should then be covered with a thin cover-glass and examined with the microscope. By this method, if the stain be blood, and not too old, the red blood-corpus- cles and sometimes the white ones as well will be usually brought into view. If the material suspected to be blood is in the form of a clot, on a knife-blade, for example, a small portion of it should be scraped off with a needle on to a perfectly clean glass slide. A thin cover-glass being pressed firmly down on the fragment until it is reduced to powder, the glass slide is then placed upon the stage of the micro- scope. A drop of distilled water being allowed to flow slowly from the margin of the cover-glass toward the powdered material, if the latter be blood the corpuscles will gradually make their appearance, and, although faint and colorless, 5 66 A MANUAL OF are usually sufficiently definite in outline to admit of identification. A red blood-corpuscle of man (Fig. 13), as seen in freshly-drawn blood, may be described as a biconcave disk, a mass or cell of protoplasm without a cell wall or nucleus, and with a diameter in its greatest width on an average of -g-^o^-th °f an inch. Micrometer. — Inasmuch as there are obtained from sup- posed blood-stains certain bodies having the size just men- tioned, and as this is usually regarded as one of the strong- est proofs that such bodies are red blood -corpuscles, the method by which they are measured must be described. The instrument used for this purpose by the microsco- pist-is an eye-piece micrometer, that is, an eye-piece upon the glass of which have been ruled a number of parallel and equidistant lines, which, on being projected upon the field of the microscope, will be seen by the ob- server to cover any objects visible there and to define their limits. To use the eye-piece micrometer, the value of the spaces between the lines must be determined for the par- ticular magnification, since these will vary with the ob- jective 'and the length of tube used. To accomplish this, there is placed upon the stage of the microscope a glass slide upon which have been ruled a number of parallel lines separated from one another by distances of y^th, r ^ ¥ th, and y^g-ffth °f an mcn respectively (Fig. 14). Let us suppose, for example, that the magnifying power used is such that ten lines of the eye-piece micrometer corre- spond exactly to the space between two of the lines upon the stage micrometer that are separated by ygVffth of an inch, the value of the spaces between the lines of the eye- piece micrometer will be then equal to jowoth °f an mcn , and an object covered by four such spaces as a white MEDICAL .lUKLSl'UUDENCK AND TOXICOLOGY. 67 corpuscle (Fig. 14, W) would have a diameter therefore of rTr$"o~o* n ~ tsW^ °^ an ' n<; ^- ft is obvious, however, that with such magnification a red blood-corpuscle, if its diameter be s^V^ 1 °f au inch, will be covered by less than four such spaces, and by more than three, since -^Vo^ 1 °^ an inch is less than ^ q ft q ^ th and more than xTTolTTr^ 1 °^' an inch. As the red corpuscles, in order to be measured, must lie within the space between two lines the value of which is known, and further, as the edges of the corpuscle must be exactly in contact with the two lines circum- scribing it, an object-glass and length of tube must be Fig. 14. R HI W P.l HI! Mill Lines of Eye-Piece Micrometer, projected upon Stage Micrometer, as seen with different magnification. used so that exactly 32 lines of the eye-piece micrometer can be counted within a space of y^-th of an inch, as each space will then be equal to sY^th °f an i ucn > and will exactly cover the red corpuscles (Fig. 14, R). Such a simple micrometric arrangement as that just described (Fig. 14) will suffice for determining whether bodies supposed to be red corpuscles have an average diameter of g^-Q-th of an inch, and, approximately at least, the diameter of larger or smaller bodies. It is obvious, however, that if the body to be measured was 300 Q-th of an inch in diameter, in order to measure it the accurately the magnification (Fig. 14) would have to be so altered that the space of the yFotn of an inch would contain exactly thirty lines instead of thirty-two. To 68 A MANUAL OF avoid the inconvenience of altering the magnification in each case — which alteration would necessitate altering the length of the tube or changing the objective, or both— Fig. 15, l. B a a Fig. 15, 2. B C a B, C, lines upon stage micrometer; A, fixed line in ocular; a, b, movable lines in ocular. microscopists make use of a form of micrometer essentially the same as that used b) r astronomers in measuring the apparent diameter of the heavenly bodies. This con- sists of an ocular (Fig. 15, l) through which may be seen MEDICAL JURISPRUDENCE AND TOXICOLOGY. 69 projected upon the stage micrometer a fixed line A, and two movable lines a, b. The latter < a 1 1 be moved across the field of the microscope by means of a wheel (not rep- resented in the figure), the distance traversed by cither of the threads from the fixed line being determined by the number of divisions through which the wheel is rotated (Fig. 15, 3). As an illustration of the manner in which this is accomplished, let us suppose that the thread b is made to coincide with the fixed line A of the ocular, and the latter is made to coincide at the same time with the line B of the stage micrometer (Fig. 15, 2), and that the wheel is turned through one hundred divisions ; that is, makes one complete rotation. It will be observed that the line b will traverse the space between the lines B and C of the stage micrometer, stopping at and coinciding with the line O. By the turning of the wheel through one hundred divisions the line b has, therefore, been made to traverse the space of the -nnjth of an inch, the space be- tween B and C of the stage micrometer having been so graduated ; consequently, if the wheel be turned through ten divisions, the line 6 will be made to traverse the yoW^ 1 °f au mcn ; an d so on proportionally. The rela- tion between the space traversed by the line 6 of the ocu- lar and the number of divisions through which the wheel is turned having been experimentally determined by means of the stage micrometer, the latter is removed, and the object-glass holding the object to be measured is substituted in the field of the microscope. To determine the size of the latter, it is only necessary then to turn the wheel until the body to be measured (Fig. 15, 3) is exactlv circumscribed by the fixed line A and the movable line 6 of the ocular, and to read oif the number of divisions through which the wheel has been turned to accomplish 70 A MANUAL OF this ; for example, y^-th of an inch : 100 divisions of wheel : : x : 20 divisions : x = 5-g-Q"th °f an mcn = diameter of body. It is evident, however, that if the wheel must be rotated through twenty divisions and a fraction of a division in order to bring the body to be measured between the lines A and b, that fraction might be such that even with a vernier attached to the wheel it would be impossible to get an exact reading, and consequently the measurement would only be approximate. It is a matter, however, of the greatest difficulty with high powers to adjust accurately the divisions of the eye-piece micrometer, whatever form of instrument may be used, to either those of the stage micrometer or to the margins of the objects to be measured, even with all the ingenious accessory contrivances that have been devised to facilitate the operation. Indeed, it must be admitted that the measurement of so small a body as the red corpuscle, even when made by a most skilful micro- scopist and with the best of modern instruments, from the very nature of the case can never be anything but an ap- proximate one. If the measurement of the red blood- corpuscle from freshly-drawn blood and under the most favorable circumstances is at best only approximative, how much more so must such measurement be in the case of a blood-stain where the size of the blood-corpuscle will depend upon the relative amount of the fluid absorbed that was used in its preparation for microscopical examina- tion ? Indeed, one of the greatest difficulties experienced in restoring the form of the blood-corpuscles obtained from a blood-stain is to prevent them becoming distorted, swollen, or even bursting from excessive absorption of the fluid used in their preparation. The size of a corpuscle, MEDICAL JUKI8PKUDENCE AM) TOXICOLOGY. 71 as obtained from a blood-stain, can only bo regarded then as representing approximately the size of the corpuscles of such blood. Further, it must be borne in mind, in this connection, that while about ninety out of every hundred red corpuscles, whether the blood be that of man or other mammals, have the same diameter, the latter depending upon the species; of the remaining ten corpuscles, some are larger, some smaller than the average corpuscle. That being the case, if it just so happened that only the ex- ceptionally small corpuscles were present, the blood, though human, might be erroneously regarded, on account of the small size of the corpuscles, as that of a dog, for example, in which the corpuscles are smaller than those of man. On the other hand, if the blood examined was that of a dog, but only the exceptionally large corpuscles were obtained, such blood, on account of the large size of its corpuscles, might improperly be considered as human. It must be admitted, therefore, that while the red blood- corpuscles of the mammalia can be shown by measurement to differ in size (see table), the blood examined being freshly drawn in each instance, red blood-corpuscles as obtained from blood-stains cannot be positively identified by such a method as human red blood-corpuscles. Any evidence offered as positive proof based upon micrometric methods that blood is human, as distinguished from other mammalian blood, must be regarded as only circumstantial at best, for the following three reasons mentioned above : 1. The micrometric method is approximative. 2. The size of the corpuscle restored is variable, depending upon the amount of fluid absorbed. 3. The size of the cor- puscles varies, even in the blood of the same mammal. 72 A MANUAL, OF Table of Blood-Corpuscles (Diameters in fractions of an inch). Birds. Mammals. Diameter. Manatee 2T0 o Elephant 27V5 Ant-eater ^759 Sloth Whale Camel Man Orang s^sa Chimpanzee 3T12 2865 1 3099 1 312 3 1 3 200 Opossum .... Rabbit Black Rat ... . Mouse Brown Rat . . . Gray Squirrel . . Ox Cat Sheep Goat Pigmy Musk Deer 3TT2 _ 1 3557 i_ 3 607 "375? 1 3 8 l¥ J 3911 _1 ¥000 1 ¥2 6 7 ¥¥o¥ _ 1 _ 5300 1 63 66 1 12325 Ostrich Owl . Swan Pigeon Diameter. 1 ■ • T6¥9 _ 1 • • 1763 1 • ■ 1806 1 _ • ' 1TJ73 Reptiles. Turtle xaVi Viper Lizard 127? 1 1555 Amphibia,. Amphiuma 3^3 Proteus £00 Siren ? |o Menopoma -$\z Fishes. Pike 2^0 Perch 21W Lamprey 2Ts¥ The red blood-corpuscles of man and the mammalia generally can be readily distinguished, however, from those of birds, reptiles, and fishes, the latter being not only relatively of large size, but oval in form and nu- cleated (Fig. 16). It should be mentioned, in this con- nection, that the red corpuscles of the camel and llama are oval, and that those of the lamprey are somewhat circular. No difficulty should arise on account of this circumstance, for, as in the case of the camelidse, the corpuscles are without a nucleus, though ovoid in form ; while in the lamprey the corpuscles are nucleated, even if circular. The fact that the red corpuscle of a bird differs in form MEDICAL JURISPRUDENCE AND TOXICOLOGY. 73 and in size from that of a mammal is important from a medico-legal point of view. As an illustration, let us suppose that in the ease of blood-stains found in a wagon Fig. 16. M AM M A L S, nrrnn £ MUSK DEER CAMEL •3200 I 1-30.99 1 1-2/45 I I-42G8 I 1-4600 I 1-12325 I 1-3123 BIRDS. Blood-corpuscles of vertebrates. in which a person was suspected to have been murdered, the explanation offered by the person accused of the crime was that the blood spilled was that of a chicken which had been killed by him for market. If, after examination, 74 A MANUAL OF the expert testified that the red blood-corpuscles obtained from the blood were round and without nucleus, that testimony alone would prove that the statement of the defendant was false, and would be presumptive evidence of guilt, and might lead to the confession of the crime and to conviction. Fig. 17. Prismatic crystals from human blood. Blood-crystals (Fig. 17), due to the crystallization of the haemoglobin or coloring matter of the blood, consti- tute an important proof of the existence of blood. 1 The blood-crystals can be readily obtained from freshly-drawn human blood by evaporating a drop of the blood to dry- ness on a glass slide, adding a drop of distilled water, and allowing the water to evaporate under a thin glass cover. The glass slide having been transferred to the stage of the microscope, the crystals will soon appear in certain forms x Preyer: Die Blut-Ory stalk. Jena, 1871; Dragendorf in Maschka, vol. i. S. 483. MEDICAL JURISPRUDENCE AND TOXICOLOGY. 75 and sizes, but usually as small prisms. 1 If the blood sub- mitted for examination has, however, undergone changes such as would have occurred in the case of a blood-clot, the following will be found a convenient methoa of ob- taining the crystals : Triturate the substances suspected to be blood in a mortar with a little common salt, add glacial acetic acid, and warm the mixture till bubbles appear ; then set aside to cool. If the substance so treated con- tains hsematin, that is, modified haemoglobin, crystals of hsematin hydrochlorate will appear as rhombic tablets, stars, or crosses. The presence of such blood-crystals may be regarded as proving that the material from which they were obtained was blood, but not necessarily human blood, since the crystals of the blood of certain animals are un- distinguishable from those of man. Therefore, the presence of blood-crystals as evidence that a suspected material from which they have been obtained is blood is even of less value from a medico-legal point of view than the presence of blood-corpuscles, since the microscopist is unable, from the form of the latter at least, to distinguish the blood of the mammalia from that of other vertebrata. The spectroscopic method of investigating blood-stains is based upon the fact that blood interferes with the trans- mission of certain rays of light, and that it gives rise to what are known as the dark absorption bands of the blood spectrum. It is well known that wheu sunlight is trans- mitted through a prism it is decomposed into the seven colors : Violet, indigo, blue, green, yellow, orange, red. If, however, a weak solution of arterial blood be placed 1 Another method is to mix together in a watch-glass a drop of blood with glacial acetic acid in excess, and evaporate to dryness slowlv over a spirit lamp. The mass so obtained, when viewed under the micro- scope, will usually exhibit the crystals in great numbers. 76 A MANUAL, OP Fig. 18. Red, Orange. Yellow. Green. ^4 olB o J> Blue. Indigo. Violet. Oxyhemoglobin, and N0 2 -Haj- moglobin: CO-Haemoglobiiu Beduced Haemo- globin. Haematin in acid solution. Haematin in al- kaline solution. Beduced Hsema- tin. Solar spectrum with Fraun- hofer's lines. I I""'"" l "T / 3 9 10 11 12 IS 14 Spectra of blood. Fig. 19. Layer of blood in a glass vessel through which the light is transmitted. Scheme of a spectroscope for observing the spectrum of blood. A, Tube. S, Slit. m m, Layer of blood with flame in front of it. P, Prism. M, Scale. B, Eye of observer looking through a telescope, r v, Spectrum. MEDICAL JURISPRUDENCE AND TOXICOLOGY. 77 between the souree of light and the prism, two dark bands will appear (Fig. 18) in that part of the spec- trum previously occupied by the yellow ray, and more particularly in that portion of the yellow ray adjoining the orange and green rays, the two dark bands being sepa- rated by that part of the yellow ray still transmitted through the blood. If the arterial blood be now replaced by venous blood, or simply deoxidized, as can be done by appropriate means, the two dark bands will disappear, and in that part of the spectrum where the yellow ray was transmitted there will appear one dark band, while that part of the spectrum lying on either side of the dark band will be occupied to a small extent by the yellow ray. By means of the spectroscope not only can a suspected mate- rial be proved to be blood and arterial distinguished from venous blood, but blood in general can be distinguished from that which has absorbed carbonic oxide gas, as also from solutions of acid alkali and reduced hsematin, the dark bands presented by their spectrum being different in each instance (Fig. 18). The spectroscopic method is the most convenient, reliable, and delicate of the different methods which have been described for investigating- blood- ed o stains. The spectroscope employed in medico-legal examinations is the same as that used in chemical and physical re- searches, the essential parts being shown in Figure 19, or it may consist simply of a spectroscopic attachment to a microscope. The delicacy of the spectroscopic method of investigating blood-stains is such that a solution con- sisting of one grain of haemoglobin, upon which the absorp- tion of the light depends, to a pint of water will interfere with the transmission of strong sunlight sufficiently to render the two dark bands visible. It thus becomes pos- 78 A MANUAL OF sible, by means of a spectroscope, to state positively that stains years old on wood, linen, or iron, even when found in a putrid condition, were made by blood. It is true that the spectra of solutions of the coloring matter of the petals of cineraria, 1 of cochineal, madder, and other red dyes, present dark bands in their spectrum, but their situ- Fig. 20. Fig. 21. Blood before coagulation. Blood-clot floating in the fluid serum after coagulation. ation is either not exactly the same as those of the blood spectrum, or they can be distinguished from those of the latter by the action of ammonia and potassium sulphate. The spectroscopic method of investigating blood-stains, reliable and delicate though it may be, does not enable the examiner to state that a suspected material is human blood, but only blood. By none of the methods, therefore, of examining blood-stains, whether chemical, microscopic, or spectroscopic, can human blood be distinguished positively from that of other animals. Coagulation of Blood. — One of the most remarkable properties of the blood is its power of separating into clot and serum, due to the coagulation and subsequent shrink- age of its fibrin (Figs. 20, 21), the process being com- 1 Of the different menstrua used by the writer to obtain the color- ing matter from the petals of cineraria, glacial acetic acid was found to be the best. MEDICAL JURISPRUDENCE AND TOXICOLOGY. 70 pleted outside the body within a period of from 10 to \'Z hours. BLOOD. Before Coagulation. After Coagulation. f Water, f T . „ . . Albumen, > i Serum. Liquor Sanguinis, -i SaUg) ^ [ [ Fibrinogen^. . "> I Clot. Corpuscles, ^ Conditions Influencing Coagulation of Blood. — While the blood does not usually coagulate in the living body, it almost invariably does so in the dead body, and within a period varying between 12 and 24 hours. There are various conditions which influence the coagulation of the blood within and without the body, some of which are better understood than others. Only those conditions in- fluencing coagulation which may have an importance from a medico-legal point of view need be here considered. Blood flowing from a small orifice coagulates more quickly than when flowing from a large one ; more quickly when it is received into a shallow rough vessel than when in a deep smooth one. The coagulation of the blood is retarded or even prevented when mixed with solutions of sodium sulphate and carbonate. Rapid freezing will prevent the coagulation of the blood ; blood so frozen will, however, coagulate if carefully thawed. A temperature of from 32° to 140° F. favors coagulation. The menstrual blood is kept in a more or less fluid condition by the vaginal secretions. The medical expert is often asked to express an opinion as to how much blood the body of the deceased contained. While it is impossible to state exactly how much blood there is iu any human body, it may be said that on an average there is one pound of blood for every eight pounds of body- weight ; that is, there would be about six- 80 A MANUAL OP teen pounds of blood in the body of a man weighing one hundred and twenty-eight pounds. This estimate is based upon the fact that twelve pounds of blood were collected during the execution by beheading of a criminal weighing one hundred and twenty-eight pounds, and that four pounds of blood were obtained after the execution by washing out the blood-vessels. MEDICAL JURISPRUDENCE AND TOXICOLOGY. <: V. are very apt to imagine that they are having sexual inter- course with their husbands, lovers, or even with the sur- geon or dentist who may be operating upon them. So true is this that it is of the utmost importance for surgeons and dentists to insist upon the presence of witnesses during the performance of operations upon women under the in- fluence of anaesthetics. Indeed, in the absence of witnesses under such circumstances, professional men have been charged and convicted of rape, though without doubt en- tirely innocent of the crime, and, extraordinary as it may appear, even though the women were never at any time examined medically. 1 Unfortunately, in the case of alleged rape upon adult women, the medical examination usually made is postponed so long that even if the crime has been committed all traces of it have disappeared. If the woman has offered much resistance, bruises will usually be found upon the thighs and legs, and sometimes also upon the arms and trunk. The most important proofs of rape upon adult women are, however, derived from the condition of the sexual organs and the hymen, and the presence of blood and semen. Among such proofs may be mentioned the soreness, swelling, laceration of the vulva and vagina, rupture of the hymen, the presence of blood and semen upon the persons and clothes of the woman and man. But it must be remembered that frequently women affected with leucorrhoea or vaginitis, in both of which dis- eases there is a discharge from the vagina simulating that produced by violence, take advantage of their condition to charge innocent men with having committed rape upon 1 Philadelphia Medical Examiner, December, 1854, p. 705. MEDICAL JUKISPKUDENCE AND TOXICOLOGY. 105 them. Further, while the discharge in leucorrhcea is mucous in character, that of intense vaginitis may be so purulent as to make it impossible to distinguish it from that of gonorrhoea. Under such circumstances, the fact that a man has gonorrhoea would not be proof that he had committed an assault upon the woman charging him with rape, since the purulent discharge in the woman might be due to vaginitis rather than to gonorrhoea acquired from the man. In the case of alleged rape upon adult women, as upon children, much importance cannot be attached to the pres- ence or absence of the hymen as disproving or proving a rape, for the reasons already given. If there be, however, other signs of violence, a ruptured or lacerated hymen would be strong corroborative evidence of a rape having been committed. Rape upon the Dead. — Occasionally the medical exam- iner may be called upon to determine whether a woman found dead had been violated before death. In the absence of witnesses, and in view of the fact that the prosecutrix can make no statement, the evidence will be necessarily entirely of a medical character. But in such cases, even if all the signs of sexual intercourse were present, it would be im- possible for the medical examiner to state whether the woman had or had not given her consent. Even on the supposition that the woman had been violated before death, it might be impossible to state positively whether the rav- isher and the murderer were one and the same person. Indeed, a woman found dead and violated may have been murdered first and violated afterwards, and not necessarily by the same person, for, horrible as the thought may be, violation of the dead is less rare than might be supposed. Indeed, it was of such common occurrence in ancient times that classical writers refer to the necessity of undertakers 106 A MANUAL, OF being watched to prevent them violating the bodies of women committed to their charge. In the case of very young girls found dead and violated, the probability is that the child had been ravished and then murdered, the ravisher hoping by that means to escape the consequences of his crime. It would hardly be supposed that a rape could or would be committed by a female upon a male. As a matter of fact, nevertheless, such cases have occurred. Unnatural Grimes. — Though not germane to the subject of this section, crimes against nature, committed either with man or beast, unnatural crimes, sodomy, psederastia, tribadism, bestiality, may as appropriately be considered in their medico-legal relations here as elsewhere. While of frequent occurrence in the East, such practices are rare in America, and are criminal and punishable by imprisonment for a term of years. In cases of sodomy both parties are held to be equally guilty, unless the person on whom the act was committed refused consent, or was a minor, an idiot, or feeble-minded. In recent cases laceration of the sphincter ani, bruises and fis- sures, and blood about the anus may be observed. Un- less, however, the examination be made very soon after perpetration of the act, all traces will have disappeared. Characteristic appearances are presented by persons addicted to such practices. Among the most conspicuous may be mentioned a funnel-shaped condition of the anus, which is usually enlarged, smooth, and destitute of ruga?. 1 Chancres and venereal warts are also not uncommonly present. 1 "Multo magis frequentem tarn nefande coitus usum significare poterit ipsius. Podicis constitutio, qui cum ex Natura rugosus existat, ex hnjus modi congressu laevis, ac planus efficitur, obliterantur enim rugae illse in ani curriculo existerites, ob assiduam membri attritionem " (Zacchias, Pauli: a, Quaestionum Medico-legqlium, Lib. v., Tit. i., Quaest. i., p. 383; b, Lib. ii., Tit. ii., Quaest. ii., p. 288). MEDICAL JURISPRUDENCE AND TOXICOLOGY. 107 CHAPTER IX. Signs of Pregnancy — Uncertainty of Duration of Pregnancy — Preco- cious Pregnancy — Unconscious Pregnancy — Pregnancy in the Dead. The subject of pregnancy is an important one medico- legally, as women, on the one band, frequently deny that they are pregnant, in order to avoid disgrace or to procure an abortion, and on the other hand as often affirm that they are pregnant, having no reason to think that they are in that condition, in order to extort money, to defraud the heir-at-law, to stay capital punishment, to avoid attendance upon a trial, etc. Actions for damages against physicians and others involving questions of pregnancy often arise in cases in which it is claimed that errors in diagnosis were committed, or that slanderous reports were circulated against the character of a virtuous woman. A pregnant female was exempted by the old Roman law from capital punishment, 1 and the law is the same in most modern countries. Hence, the summoning of twelve matrons or discreet women in old times under the writ of de ventre inspiciendo to determine whether a woman was pregnant or quick with child — an office now performed by the city's physician or by a jury of physicians. The signs of pregnancy may be described as being of two kinds : uncertain and certain. The former kind, as the name implies, is, from a medico-legal point of view at least, but of little importance as compared with the latter. 1 "Quod prsegnatis muiieris danmata? poena differatur quoad pariat" (Beck, op. cit., vol. i. p. 250). 108 A MANUAL OF Among the uncertain signs of pregnancy may be men- tioned the suppression of the catarnenia, morning sickness, enlargement of the abdomen, quickening, development of the breasts, kiesteine in the urine, the violet color of the vagina. Suppression of the menses, when occurring after inter- course, only in a woman who had hitherto been regular, may be regarded as a very probable sign of pregnancy. As the menses may continue, however, throughout preg- nancy, as they may only appear during that condition, as they may never appear at all, even in women who bear children, and as they are also absent in certain diseases, it is evident that neither their absence nor their presence can be regarded as a proof of pregnancy or non-pregnancy. But it should be mentioned that not unfrequently women desiring to conceal their pregnancy stain their linen with blood and even with menstrual blood, borrowed for that purpose. Nausea is usually an accompaniment of pregnancy, occurring frequently as early as the second or third week after conception. It generally passes away about the time of quickening, but may continue throughout the whole period of pregnancy. In many cases of pregnancy nausea is absent ; on the other hand, it is of frequent occurrence in many diseases. But little importance can therefore be attached to nausea alone as a sign of preg- nancy. The enlargement of the abdomen in a pregnant woman becomes evident at the end of the third month, the uterus then rising out of the pelvic cavity. By the end of the fifth month the uterus is halfway between the pelvis and the umbilicus, and at the sixth month at the umbilicus. During the seventh month it is at a point MEDICAL JURIS PRUDE NO K AND TOXICOLOGY. 109 midway between the umbilicus aud ensiform cartilage, reaching at the end of the eighth month the ensiform cartilage. During the last month the tumor widens and falls forward. Enlargement of the abdomen may be due, however, to ovarian dropsy and tumors, ascites, flatus of the intestines, impacted feces, enlargement of the spleen and kidney, and distention of the bladder. The medical examiner would certainly not be justified, therefore, in expressing the opinion that a woman was pregnant simply because there was enlargement of the abdomen. Quickening is the first perception by the mother of the movements of the foetus. These movements, which occur usually some time between the sixteenth and the twenty- fourth week, may be due either to the uterus or to the foetus. Nervous, excitable women, especially those want- ing children, frequently imagine, however, they are preg- nant, mistaking the movements of their intestines or the contractions of their abdominal muscles for those of a foetus. Quickening, being entirely a subjective symptom, is, therefore, a very unreliable sign of preg- nancy. The breasts usually develop during the period of preg- nancy, becoming larger and fuller as the secretion of milk increases. Large veins make their appearance, the nipples become more prominent, the areola widens and darkens in hue, especially in brunettes. Enlargement of the breasts, however, is not a proof of pregnancy, inasmuch as it occurs in cases of uterine fibroids, and in various other ovarian aud uterine disorders. Even the secretion of milk would not warrant the statement that a woman was pregnant, since milk is secreted occasionally by unimpregnated women, young girls, and even by men. Indeed there have been cases in which the secretion of milk bv men has been 110 A MANUAL OF so copious that they have been able to perform, for years, the office of wet-nurse. 1 By kiesteine is understood the fatty pellicle which forms on the urine of pregnant women that has been standing some days. It appears to consist of a combination of casein and phosphates. As kiesteine is not peculiar to the urine of pregnant women, being found sometimes in the urine of men, its presence cannot be regarded as a proof of pregnancy. The violet color of the vagina, appearing about the fourth week of gestation, due to venous conges- tion, may be regarded as a valuable sign of pregnancy, but an uncertain one, since it is not invariably present. Ballottement. — Among the so-called "positive signs" of pregnancy are included ballottement, change in the body and cervix of the uterus, the active movements of the child, the pulsation of the foetal heart, the uterine and umbilical sounds. By ballottement is determined the pres- ence of a foetus about the fifth or sixth month of pregnancy. In performing it, the woman is made to stand upright and the finger of one hand is introduced into the vagina up to the os uteri, while the other hand is placed upon the abdo- men, so as to steady the uterine tumor. If the tip of the finger be now suddenly pushed up against the os uteri, a sensation, should a foetus be present, will be felt like that of a body rising and falling in a liquid. This is, how- ever, an uncertain sign of pregnancy, since any floating tumor in the uterus will impart the same sensation to the finger as that due to the foetus. At about the fifth month of pregnancy, the os uteri is directed backwards, and has a velvet-like feeling ; the shortening of the cervix becomes evident at this time and continues until the ninth month, when the cervix ceases 1 Dunglison : Human Physiology, eighth edition, vol. ii. p. 520. MEDICAL JURISPRUDENCE AND TOXICOLOGY. Ill to be distinguishable from tlic body of the uterus. The active motions of the child can usually be felt about the fifth month of pregnancy, or even earlier, by placing a cold hand upon the surface of the abdomen. Intestinal movements must not be mistaken, however, for those of a foetus. It should be remembered also that not unfrequently in cases of pregnancy the movements of the foetus are not perceptible. The uterine sound, a peculiar blowing or whistling sound, synchronous with the maternal pulse, and due probably to the passage of blood through the uterine arteries and placental vessels, can usually be heard over most of the abdomen as early as the middle of the third month of pregnancy, but more distinctly as pregnancy advances. As uterine sounds can, however, be heard in cases of enlargement of the uterus as from tumors, such signs are very unreliable signs of pregnancy, and the same may be said of the umbilical sounds due to the flow of blood through the umbilical vessels. Pulsation of the Foetal Heart. — Indeed, of all the so- called " certain signs " of pregnancy, the pulsation of the foetal heart is the only certain and positive one, and then only when it can be so distinctly heard as to be counted. The foetal sound is not synchronous with the pulse of the mother, the foetal heart beating at a rate of one hundred and thirty-six beats to the minute, and even faster. It resembles the ticking of a watch, and is heard over different parts of the abdomen, but best between the ilium and the umbilicus on either side. It may be heard as early as the middle of the fifth month, but much more distinctly as pregnancy advances. 1 1 Scanzoni: Lehrbueh der Geburtshulfe, Vierte Auflage, "Wien, 1867, vol. i. S. 160. 112 A MANUAL OF Corpus Luteum. — Importance was attached at one time to the presence or absence of a corpus luteum, or the yellow body developed through modification of the lining mem- brane and contents of the Graafian follicle from which an ovum had escaped, as proving or disproving pregnancy. A foetus is not unfrequently found, however, in the uterus where there is no trace of a corpus luteum in either ovary ■ and, on the other hand, a well-developed corpus luteum, undistinguishable from that of pregnancy, may be found in the ovary of a woman who had never been pregnant, and even in that of a virgin. The presence or absence of a corpus luteum cannot then be regarded as having any importance in medico-legal cases involving questions of pregnancy. Responsibility of Mistaken Diagnosis. — As the so-called "certain signs" of pregnancy, with the exception of the pulsation of the foetal heart, are only relatively more cer- tain than the uncertain signs, the medical examiner should be extremely cautious, under any circumstances, in stating positively that a woman is pregnant, and especially if she be unmarried and of previously good character. On more than one occasion has the reputation of a virtuous woman been ruined and the happiness of her family destroyed by a too confident examiner mistaking a condition of disease for that of pregnancy. When once the virtue of an inno- cent woman has been thus impugned, and her previously good character taken away, though in time the injustice of the charge will surely be proved, reparation will come too late, and no atonement can be made for the wrong done the woman or the misery inflicted upon her family. Apart from the injury due to a mistake in diagnosis under such circumstances, the examiner should remember that as Plate l. Fig. 1.— Ovary of woman two days after menstruation, showing earliest stages of trans- formation of a ruptured and bloody Graafian follicle into a corpus luteum. Fig. 2.— Ovary of woman nine days after menstruation: the dark spot is the cicatrice- the surrounding yellow circle is the corpus luteum shining through the transparent tissue" Fig. 3.— Ovary of woman at term of pregnancy, showing corpus luteum with firm white central clot. Fig. 4.— Ovary of woman twenty davs after menstruation: besides laree fresh corpus luteum are seen two smaller old ones, and Graafian follicles of different sizes (Daltox). MEDICAL JURISPRUDENCE AND TOXICOLOGY. 1 L'3 the best obstetricians may be mistaken, his own reputation as a medical expert may be at stake. Cases of supposed pregnancy differ in one respect from other cases demanding the attention of the medical jurist — namely, there is no necessity that a positive opinion should be expressed upon the subject. No harm can result from the medical examiner refusing to state positively whether a woman is pregnant or not. It is far better to give the woman, if unmarried and of good character, the benefit of the doubt, than positively commit yourself to the expression of an erroneous opinion in the case. It should always be remembered that nature will soon answer so positively the question whether a woman is or is not pregnant that there will be no necessity of the examiner weighing the relative value of the uncertain and certain signs of pregnancy. Duration of Pregnancy. — The determination of the dura- tion of pregnancy under certain circumstances, as in cases involving questions of legitimacy and inheritance, may be- come a matter, medico-legally, of the greatest importance. It may as appropriately be mentioned here as elsewhere that the ordinary period of gestation is nine calendar months (270 to 276 days), or ten lunar months (280 days), the physi- ological presumption being that parturition occurs at the period which would correspond to the tenth menstrual pe- riod since the last one. The greatest difference of opinion prevails, however, as to what shall constitute the longest and shortest possible periods of gestation. The difference of opinion in this respect depends to a great extent upon our ignorance as to the exact moment of conception. As conception may take place at any moment of the period intervening between the menses, it is evident that there may be a difference on this account alone of twenty-eight 8 114 A MANUAL OF days in the period of gestation, according as conception was supposed to have taken place immediately before the period at which the menses would have occurred had not concep- tion taken place, or immediately after the last menses which actually did occur. Further, the duration of preg- nancy varies very much in different women on account of personal idiosyncrasies, as well as on account of other causes not understood. Obstetricians have claimed that mature children have been born as early as from 210 to 217 days, 1 and as late as from 313, even to 325, days after sexual intercourse, there being a difference between these very exceptional extremes of as much as 96 days. Cases are not rare, however, in which the difference in the duration of gestation in cases of mature children amounts to as much as 44 days, the two ex- tremes of gestation being 249 and 293 days respectively. It should be mentioned in this connection that while a child born after a period of protracted gestation is neither larger nor better developed than one born after the average period, a child born only seven months after sexual intercourse is always immature and imperfect — readily distinguishable from one born after the average period. 2 It is for this reason that the statement that a mature child is born seven months after sexual intercourse must be regarded as most exceptional. In tropical countries women become preg- nant at a much earlier age than in temperate climes. Thus, in India and Abyssinia it is no uncommon occurrence for girls of only eleven and twelve years of age to bear children. Pregnancy has been known to occur, however, even in children of only eight and nine years of age. On the other 1 Beck : op. cit., vol. i. p. 599. 2 Montgomery : Signs and Symptoms of Pregnancy, second edition, London, 1856, pp. 523, 546. MEDICAL JURISPRUDENCE AND TOXICOLOGY. L15 hand, it is well known that women of from fifty to sixty years of age and even older have borne children, giving birth to twins, in some rare instances, even at that advanced age. Unconscious Pregnancy. — Under certain circumstances it may become a question whether a woman can become pregnant while unconscious. There can be no doubt of the possibility of such an occurrence, as it is well known that women have borne children in consequence of having been ravished when in a state of unconsciousness induced by the use of narcotics or anaesthetics. Pregnancy in the Dead. — It not unfrequently occurs that the medical examiner is required to determine whether a woman was pregnant at the time of her death, as, for exam- ple, in cases where the charge is that of seduction and murder. In considering the subject of putrefaction, it will be remem- bered that attention was called to the remarkable fact that the unimpregnated uterus will resist decomposition longer than any other organ in the body months after burial ; therefore, it becomes possible to say whether a woman died pregnant or not. On the other hand, even after years of interment, if the woman died pregnant and the foetus had reached the period of ossification, traces of its bones will be found among those of its mother. 116 A MANUAL OF CHAPTER X. Foeticide — Development of Embryo — Formation of Placenta, of Moles — Changes Undergone by the Uterus during Pregnancy — Of the Means of Producing Foeticide — Abortion from Natural Causes. The unlawful expulsion of the foetus constitutes foeticide, or criminal abortion. By the term abortion or miscarriage is understood, medically, the expulsion of the foetus before the seventh calendar month of gestation ; that is, before it is viable or would survive. After this period the expulsion is called " premature labor." Legally, however, such a dis- tinction is not made; the unlawful expulsion of the foetus at any period of gestation being regarded as abortion. At one time the law also recognized a distinction between an abor- tion produced before and after quickening, the punishment being more severe in the latter than in the former instance. At the present time the criminality of the act is the same, whatever may be the period of gestation at which the abortion is committed. Foeticide, although an extremely common crime, rarely becomes the subject of trial unless it involves the death of the mother, in which case it is regarded as murder. The proofs that a criminal abortion has been committed are derived from the condition of the foetus or fcetal remains, whether expelled from the uterus or still retained within it, and from the condition of the mother. Development of the Human Embryo. — The human em- bryo, 1 at one of the earliest periods of development yet obtained, that is, about from ten to fourteen days after con- ception, consists (Fig. 26) of a tube, the primitive neural canal, more or less open on top; from the under part of 1 Haeckel : Anthropogenie, Vierte Auflage, Erster Theil, Leipzig, 1891, S. 365. MEDICAL JURISPRUDENCE AND TOXICOLOGY. 117 which hangs a globular-like bag. The latter, through subse- quent constriction, divides into an upper and lower portion Fig. 27. Fig. 26. Human embryo, natural size, fourteen days old (Haeckel). Fig. 28. Human embryo, magnified ten times, about ten days old : a, um- bilical vesicle ; c, b, d, primitive spinal cord ; e, remains of amnion (Haeckel). Human embryo, natural size, three weeks old (Haeckel). continuous with each other, which become respectively the primitive alimentary canal and the umbilical vesicle. The embryo, not longer than the one-twelfth of an inch, and inclosed within the amniotic folds, does not lie naked within the uterus ; but within the zona pellucida (Fig. 27) or the original membrane which inclosed the yelk, or the con- tents of the egg. The zona pellucida being covered, however, with little villous-like processes, is now known and hence- forth as the chorion. By the 21st day of uterine life the embryo (Figs. 28, 29), having attained a length of about the 118 A MANUAL OF one-sixth of an inch, rudimentary eyes and ears, the mouth, three cerebral vesicles, bronchial arches and clefts, umbilical vesicle, allantois and amnion are all developed. At the end of the first month, the embryo, being one-half an inch Fig. 29. Fig 30. Human embryo magnified, three weeks old : a, eye ; m, mid-brain; o, ear; k, visceral arches ; c, heart (Haeckel). Human embryo, natural size, six weeks old (Haeckel). long and weighing perhaps about twenty grains, is still further developed and is provided with rudimentary limbs. By the end of the sixth week the embryo (Fig. 30) has grown larger, and the limbs are better developed, attaining at the end of the second month (Fig. 32) a length of one inch, and weighing about one-eighth of an ounce. The fingers aud toes are also now indicated, and ossification has begun in the lower jaw, clavicle, ribs, and vertebral bodies. At the third month the embryo (Fig. 31) varies in length from 2 to 4 inches and weighs from 1 to 4 ounces ; the sex can usually be distinguished by the ex- ternal genitalia, and the placenta is beginning to be formed. Formation of the Placenta. — It will be observed that the Plate 'J. sa.ss° - •- -. ■- • -. > ; MEDICAL JURISPRUDENCE AND TOXICOLOGY. 119 villous processes of the chorion, which have hitherto cov- ered the latter membrane throughout its whole extent, are now limited to that portion of it in contact with the de- cidua scroti na, or that part of the hypertrophied mucous membrane of the uterus into which the villous process s Fig. 31. Human embryo, natural size, three months old. (Haeckel.) of the chorion still remaining insinuate themselves. The fusion of the two constitutes the placenta (PI. 2, Fig. 1). Of the remaining portion of the hypertrophied mucous membrane of the uterus, that part which ultimately grows around the ovum is known as the decidua reflcxa, and 120 A MANUAL OF that in contact with the wall of the uterus, the decidua vera. The villous processes of the chorion, when examined with the microscope, present so characteristic an appearance (Fig. 33) that their presence may be accepted as positive Fig. 32. Fig. 33. mm.' Human embryo magnified, eight Compound villosity of human weeks old : v, fore-brain ; m, mid- chorion, ramified extremity : from brain; h, hind-brain; n, after-brain; a three months' foetus, magnified c, heart ; /, upper extremity ; b, lower thirty diameters (Dalton). extremity ; s, tail (Haeckel). proof of the existence of the embryo, even if not a trace of the latter be found. 1 The general appearance of a villous process is like that of a sea-weed originating in the cho- rion by a trunk which divides and subdivides into filament- ous branches, swollen here and there, terminating in rounded bulbous extremities, and consisting internally of a finely-granular substance containing nuclei. At first the 1 Dalton, John C. : Human Physiology, seventh edition, Philadelphia, 1882, p. 647. MEDICAL JURISPRUDENCE AND TOXICOLOGY. 121 villou.s processes of the chorion arc without bloodvessels, but with the development of the allautois they become vas- cular through prolongation of the terminal allantoic vessels, which are disposed in loops. The placenta (PI. 2, Fig. 2) or after-birth, consisting essentially of the interlacement of the bloodvessels of the embryo with those of the mother, is a flattened fleshy, vascular, dish-like mass, round or ovoid in shape and with a diameter of from six to eight inches. It is the organ by means of which food and oxygen are conveyed from the blood of the mother to that of the embryo. The process by which this is accomplished is, however, by osmosis, as there is never at any period of gestation an anastomosis of the maternal and foetal blood- vessels. Such being the structure and development of the pla- centa, it is evident that, just in proportion as the foetal and maternal portions of the placenta become more and more intimately fused together, the greater will be the difficulty experienced and risk run in the expulsion of the foetus from the uterus. It is for this reason that an abortion committed after the third month of gestation may be attended with such fatal consequences, the hemorrhage resulting from the rup- ture of the bloodvessels being at times very great. Indeed, at a late period of gestation the maternal bloodvessels become dilated into great sinuses, veritable blood lakes. On the other hand, if gestation has not advanced beyond the third month, the embryo may, under certain circumstances, be expelled entire from the uterus, very much as a glove is removed from the fingers, without any serious conse- quences. Subsequent Changes Undergone by the Human Embryo. — The subsequent changes undergone by the embryo during the last six months of pregnancy are of interest, medico- 122 A MANUAL OF legally, as enabling the examiner to state the probable age of a foetus obtained from a supposed case of abortion. At the fourth month the fcetus is 5 to 6 inches long and weighs about 3 ounces, the umbilical cord measuring about 7 inches in length. At the fifth month the foetus has attained a length of 6 to 7 inches, weighs from 5 to 7 ounces, and is covered with the vernix caseosa ; the hair of the head and body, or lanugo, is quite distinct, and the umbilical cord is about 12 inches long. If abor- tion occurs at this period of gestation, the membranes are first ruptured, and then the foetus is expelled from the uterus. At the sixth month of pregnancy the foetus varies in length from 9 to 10 inches, weighs a pound or more, and meconium is usually found in the intestines. At the end of the seventh month the foetus is usually 14 inches long, weighs two and a half to three pounds, the eyes are open, the membrane of the pupil is disappear- ing, one testicle has descended into the inguinal canal. If the child should be born at this period, the arms and legs will be bent in the position they assumed in the womb, and it will be viable. At the eighth month the foetus is sixteen inches long, weighs between three and four pounds ; the skin has become thicker, and is covered with fine soft hair ; one testicle, usually the left, has descended into the scrotum. At the end of the ninth month, or at full term, the foetus varies in length from eighteen to twenty inches, and weighs on an average seven pounds. The intestines are nearly filled with meconium; the bladder contains urine; both testicles have descended into the scrotum. As aiding in determining the age of the foetus, it may be mentioned that at full term the umbilical cord is usually inserted about eight to ten lines below the centre of the body ; whereas, at an earlier period of gestation, the point MEDICAL JURISPRUDENCE AND TOXICOLOGY. 123 of insertion is at the middle of the body. The general development of the brain, the extent to which the cere- bellum is covered by the cerebrum, the particular fissures that are present will also serve to determine the age of the foetus. The importance of the presence or absence of an osseous deposit in the inferior epiphysis of the femur has already been referred to (p. 45). It should be mentioned, in connection with the subject of the length and weight of the foetus at full term, that these may vary considerably. 1 Thus, for example, it is well known that children have been born at full term who measured as much as twenty-four and even thirty-two inches, and who weighed as much as seventeen and three-quarter pounds, 2 and eighteen pounds and two ounces, 3 respectively. On the other hand, chil- dren at full term not unfrequently weigh only from four to six pounds. There is usually no difficulty experienced in recognizing an embryo in situ, or even amid the contents expelled from a uterus in cases of abortion, unless the latter be committed in the very early periods of gestation. Holes. — Under certain circumstances the medical ex- aminer may be called upon to determine whether peculiar growths, either formed in the uterus or expelled from it, are polypi or membranous in character, as due to dys- menorrhea, or what are known as molesS It is most important that the true nature of the latter, when present, should be recognized, as moles, being due to disease of the 1 As to variability in size and weight presented by the foetus at differ- ent periods of intra-uterine life, compare Casper, vol. iii. pp. 15-17 ; Guy and Ferrier, p. 88; Tidy, part ii. p. 59; Wharton and Stille, vol. iii. p. 75; Woodman and Tidy, pp. 647, 712. 2 Owens : Lancet, December, 1838, p. 477. 3 Meadows : Medical Times and, Gazette, August 4, 1860, p. 105. 4 Montgomery : op. cit., pp. 255, 269, 326, 353. 124 A MANTJAL OF placenta or of the foetal membranes, are as much proof of a pregnancy having existed as the presence of the embryo itself. Moles, when due to disease of the placenta, are either fleshy or fatty. A fleshy mole consists of layers of a fibrinous material inclosing a cavity in which the remains of the foetus are sometimes formed. While the cause of fleshy moles is obscure in some instances, they appear to be due to hemorrhage into the chorion. A fatty mole differs more particularly from a fleshy one, in that a fatty degeneration is an accompaniment of the early death of the foetus. The hydatiform, or vesicular mole, is due to the villous processes of the chorion becoming infiltrated with serum, and hanging in masses like bunches of grapes. A true hydatid — that is, a helminth of the uterus — is exceed- ingly rare ; indeed, it is very doubtful if it has ever been found. The proofs of an abortion having been committed, as derived from an examination of the mother, are not very positive, if the act has been performed at an early period of pregnancy. The hemorrhage and relaxed con- dition of the vagina, for example, and the somewhat dilated condition of the os uteri, might be attributed to menstru- ation. If the pregnancy was, however, far advanced at the time of the occurrence of the abortion, the proofs will usually be sufficiently strong to establish the fact. It is far more difficult, therefore, for a woman to conceal her pregnancy and the fact that an abortion had been com- mitted to save her from exposure, at a late period of ges- tation than at an early one. If death follows within three days after abortion, the post-mortem examination will generally establish the fact that an abortion was committed. If several weeks, however, have elapsed, little or nothing will be learned by the autopsy, as the parts involved will MEDICAL JURISPRUDENCE AND TOXICOLOGY. 125 have usually reassumed by that time their usual con- dition. Determination of Foeticide. — In every case of foeticide the vagina and uterus should most carefully he exam- ined for metritis and marks of violence which might have been produced by the use of instruments. Wounds of the vagina would rather indicate that they had not beeii made by a professional abortionist, but by one who was inexperienced in such work and who had been rendered nervous in attempting to perform the opera- tion. If the neck of the uterus or its fundus be found perforated, or the placenta wounded, the inference to be drawn would be that pointed instruments had been used, though not necessarily, since fatal wounds have been also inflicted by blunt instruments. The most common causes of death in cases of abortion as produced by instru- mental violence are hemorrhage and peritonitis. The stomach and intestines should also be carefully examined in cases of foeticide, as they present, not unfrequently, evidence that irritant poisons have been taken. Remains of cantharides, tops of savin, ergot may be found ; or the oils of savin, tansy, pennyroyal may be recognized by their odor or by appropriate chemical means, such as distillation, etc. The shape and size of the uterus should be carefully noted in cases of foeticide, as they enable the examiner to determine approximately at least the age of the fcetus. The normal uterus in the unimpregnated condition meas- ures about two and a half inches in length, one inch and three- quarters in breadth, and one inch thick. As pregnancy advances, the uterus increases gradually in size — very little change being noticeable, however, during the first month. During the second month, the increase is considerable, By the end of the third month it has attained a length of 126 A MANUAL, OF five inches, including one inch for the cervix. At the end of the fourth month, the uterus is five inches long from the fundus to the beginning of the cervix, and at the end of the fifth, sixth, and seventh month it is six, seven, and eight inches long, respectively. At eight months the uterus varies in length from nine to nine and a half inches, and at nine months from between ten and a half to twelve inches in its total length. While the thickness of the walls of the uterus at full term is about the same as that in the unimpregnated condition, or from one-third to Fig. 34. Fig. 35. Cervix uteri (at about the sixth month of utero-gestation) showing little or no absorption. Cervix uteri (at about six weeks later than Fig. 34) showing evident absorption. two-thirds of an inch within a few hours after delivery, they may become, through contraction, at least two inches thick. The changes in the shape of the uterus presented at different periods of gestation are also very characteristic. From being flat and pyriform, the uterus, after impregna- tion, becomes globular ; the cervix also, as already men- tioned, gradually shortens towards the end of the fifth month, losing about a quarter of its length each succeed- MKDICAL JURISPRUDENCE AND TOXICOLOGY. 127 ing month, until, at the end of the ninth month, it has disappeared entirely (Figs. 34, 35, 36), the form of the uterus being then ovoid. After delivery at full term the uterus begius usually to contract, its size being reduced within two days to six inches in length and four in breadth. Fig. 36. Cervix entirely disappeared and expanded over uterine contents. By the end of the first week it has so contracted as to measure usually from 5 to 6 inches in length. At the end of the second week the uterus is about four inches long and one and a half inches broad. By the end of the sec- ond month it has returned to its normal size. In those cases, however, in which death occurring at full term is due to hemorrhage, no contraction of the uterus will have taken place. If the woman, however, has survived for a few days, the uterus will be found more or less contracted. During pregnancy the round ligaments and Fallopian tubes increase in size and become more vascular ; the broad ligaments are gradually effaced through the great develop- ment. Means of Producing Foeticide. — Among the means first tried by women to bring on a miscarriage may be mentioned the effects of violence, such as submitting to a severe beating, jumping from high places, as tops of fences, gates, etc., venesection, emetics, and drastic ca- 128 A MANUAL OF thartics. 1 As a general rule, however, except in the case of very feeble or weakly women, or in those who are pre- disposed to miscarriage, such measures fail to produce an abortion. The emmenagogues, or the drugs known popu- larly as abortives, are then next resorted to, on account of the power they are supposed to possess of inducing uterine contractions and of thus causing the expulsion of the foetus. Among these the most commonly used may be mentioned ' ergot or spurred rye, cotton-root, savin, or the tops of the juniperus sabina, tansy, pennyroyal, and rue. But large doses may be taken of these drugs without causing uterine contraction, while the oils of savin and tansy have frequently caused death, through gastritis or peritonitis being produced through their irritant properties. All such means having failed to produce an abortion, instrumental violence, as a last resource, is made use of as the only certain means of inducing uterine contractions and of so insuring the expulsion of the foetus. The rupture of the foetal membranes, however skilfully preformed, is a most dangerous operation, always liable to be followed by the most serious, if not fatal, consequences, death being frequently caused, as already mentioned, by either hemor- rhage or peritonitis. When the operation is performed by a professional abortionist, long, narrow, sharp-pointed in- struments are made use of, but when self-inflicted, which is not unfrequently the case, the woman uses any articles that may serve her purpose, such as knitting-needles, pen- holders, long wires, glove-stretchers, etc. Abortion from Natural Causes. — It should be mentioned, in connection with the subject of foeticide, that abortion very frequently results from natural causes. Indeed, with some lr rardieu: Etude Medico-legale sur I' Avortement, troisieme edition^ Paris, 1868, pp. 28, 99. MEDICAL JUE1SPEUDENCE AND TOXICOLOGY. 12!) women it appears to be habitual, abortion occurring at every pregnancy, especially in theearly months of gestation, though every effort has been made to prevent it. As might be ex- pected, the tendency to abortion is most marked at the men- strual periods. Predisposition to abortion appears to be due to causes which affect the mother, such as syphilis, small- pox, albuminuria, etc., or those which affect the child, as death of the ovum, disease of the placenta. Advantage is no doubt often taken of this natural tendency to abort by producing abortion criminally. As natural abortion usually occurs at about the third or fourth month of pregnancy, and as this period is also the one at which a criminal operation is performed, the fact that the foetus comes away entire would indicate that the abortion was due to natural causes, or at least not to instrumental violence. If, how- ever, the foetus be expelled first and the ruptured mem- branes afterwards, the conclusion would be that instruments had been used. Abortion may sometimes be feigned by women, in order to extort money on the charge of seduction and consequent pregnancy. The examination of the woman will usually be sufficient, under such circumstances, to disprove the charge. The criminality of foeticide is not excused by the fact that the woman was not pregnant, or by the fact that the pregnancy was extra-uterine. Under certain circum- stances it may become necessary to perform an abortion, as in cases, for example, where the deformity of the pelvis makes the delivery of a living child at full term a physical impossibility. In all such cases the attending physician should insist upon a consultation being held ; and the patient and her family, should be fully informed as to the nature of the case before so serious an operation is under- taken. 9 130 A MANUAL OF CHAPTER XI. Infanticide — Live Birth — Appearance of Infant Born at Full Term — Means of Determining whether Child has Breathed — Docimasia Pul- monum — Objections to Hydrostatic Test — Docimasia Circulationis — Size of Liver and Contents of Stomach in New-born Child— Exam- ination of Mother — Signs of Recent Delivery — Means by which Infanticide is Committed. By infanticide is meant, medico-legally, the murder of the new-born child, it being immaterial whether the child is murdered immediately or a few days after its birth. The law assumes, until it is proved to the con- trary, that every child is born dead, on account of the fact that so many children are brought into the world who are either dead or die shortly after birth. Inasmuch as this is the law, the prosecution, and not the defendant, must prove that the infant alleged to have been murdered was born alive. For this reason great difficulty is usually experienced in convicting a woman charged with the crime of infanticide. Apart from this difficulty she is often de- livered in the absence of witnesses, or the child is con- cealed or destroyed. The jury also sympathizes to such an extent with a woman accused of this crime that conviction cannot easily be secured. Medico-legally, to be born alive implies complete expulsion of a living child from the mother. 1 A child, for example, is not born alive if any portion of it, except the umbilical cord, is retained within the vulva. By this figment of the law, therefore, the de- struction of a living child, if only partly born, does not constitute murder. 1 Guy and Ferrier: op. cit., p. 101; Tidy: op. cit., part ii. p. 248; Taylor: op. cit., p. 592. MEDICAL JURISPRUDENCE AND TOXICOLOGY. 131 Appearance of an Infant Born at Full Term. — In infanticide the child is generally born at full term. But, inasmuch as children are frequently brought into the world at an earlier period of gestation, either by natural or artificial means, it is important for the medical examiner, in cases of infanticide as well as of foeticide, to be able to state, from an inspection of the infant, its probable age at birth. The general appearance presented by an infant born alive at full term is as follows : Remains of the vernix caseosa or sebaceous matter are usually found be- hind the ears and under the arm-pits ; the hair is dry and clean ; the eyes are half open, and cannot be kept closed ; the ears do not lie close to the head ; the caput succedaneum, or swelling on the back of the head, is well marked ; the thorax is distinctly arched, and the diaphragm much de- pressed. A dead-born child is usually covered with the vernix caseosa ; the hair is agglutinated ; the eyes are closed ; the ears lie close to the head ; the thorax is flat- tened and unexpanded ; the lungs lie in the posterior part of the thorax, are granular, and do not crepitate upon pressure. In case of the death of the foetus some time before birth, the body will be found flaccid and flattened, as if it had been macerated ; the cuticle may be more or less detached, especially upon the abdomen ; the head lies flat, howsoever it may be placed, the cranial bones moving readily upon one another; the cellular tissue is infiltrated with bloody serum. The proofs of a child having breathed, and therefore of having lived, though not necessarilv of having been born alive in the legal sense, are derived from the condition of the respiratory, circulatory, and abdom- inal organs. 3Ieans of Determining whether the Child has Breathed. — 132 A MANUAL OF Wliile the vaulted character of the thorax, the compara- tive depression of the diaphragm, the relation of the larynx to the epiglottis, the situation, volume, color, consistence, absolute or relative weight, the specific gravity of the lungs, may all be important under certain circumstances in en- abling the examiner to determine whether an infant has breathed, nevertheless the hydrostatic test is the only one that can be relied upon, and even that with certain quali- fications, to be presently mentioned. The principle of the hydrostatic test, or the docimasia pulmonum, is based upon the fact that while the lungs of an infant that have been aerated will float when placed in water on account of the inspired air, those of an infant that have not been aerated will sink. To apply the hydrostatic test, the lungs should be removed from the chest of the infant and put in a suf- ficiently capacious vessel containing distilled water at 60° F. If the lungs float upon the surface of the water, that will prove that they have been aerated. It is desirable also that each lung should be divided into a dozen or more pieces, compressed, and then tested separately in the same manner. If after compression all the pieces float, very complete aeration would be indicated. It must be admitted that the hydro- static test, while it serves to determine whether the lungs of the infant had or had not been aerated, does not neces- sarily prove that the child had breathed, still less had been alive in a medico-legal sense, although it may establish a strong presumption of the fact ; since the head of the infant may be retained sufficiently long in the uterus or the vagina, as in certain elbow or breech presentations, for the infant to breathe though subsequently born dead, and, though not probable, it is not impossible that the air found in the lungs of the infant may have been artificially introduced, developed through putrefaction, MEDICAL JURISPRUDENCE AND TOXICOLOGY. 133 or be emphysematous in nature. Apart from the diffi- culty of artificially inflating the lungs of an infant in situ in cases of infanticide, nothing of that kind would be attempted, since it would be the object of the de- fendant to prove that the infant had been born dead, and not alive. As a general rule, there is no great difficulty experienced in determining whether the buoyancy of a lung is due to air inspired or to gases developed within it through putrefaction, since the air in the latter case is not found in the air-vesicles of the lungs, but in the cellular tissue and in the form of large bubbles, which disappear completely under pressure. Moreover, lungs in a state of putrefaction differ in appearance very much from healthy lungs, being greenish-yellow in color, having but little con- sistence, and emitting a fetid odor. It may be mentioned, also, in this connection, that as the lungs of the infant do not putrefy as rapidly as the other organs, if these organs are found undecomposed, then any buoyancy exhibited by the lungs could not be due to putrefaction. As it is very doubtful whether emphysema is ever spontaneously developed in the lungs of an infant, the objection that the air in the lungs could be developed in this way is without foundation. On the other hand, it may be objected that the fact that the lungs sink when immersed in water does not necessarily prove that the infant had not breathed, since the unaerated condition of the lungs might be due to disease. AVhile it is true that the density of the lungs will be so much in- creased by pneumonia or congestion that they will sink in water, these diseases occur so rarely in new-born children that but little importance need be attached to such an ob- jection. Notwithstanding that the value of the hydrostatic test has been questioned, that it cannot be expected to prove absolutely that the child has breathed, still less been born 134 A MANUAL OF alive, medico-legally, yet if the lungs of an infant do float in water, the examiner will be warranted, under ordinary circumstances, in stating that the infant had breathed, and in all probability had been born alive. The test of an infant having been born alive, or rather of having breathed, based upon the changes undergone by the heart and certain bloodvessels, after respiration has been estab- lished, and known as the docimasia circulationis, is of rather limited application, as will become apparent when the differences between the foetal and adult circulations are considered. Foetal Circulation. — The principal peculiarities in which the circulation of the foetus differs from that of the adult are that little or no blood flows through the lungs of the foetus, the placenta being the organ by means of which the blood is aerated, and that the right side of the heart communicates with the left, the blood being, therefore, neither arterial nor venous, as in the adult, but mixed. In the foetus (PI. 3), part of the blood flows directly from the rightauricle through the foramen ovale into the left auricle, instead of indirectly by the right ventricle, pulmonary artery, lungs, and pul- monary veins ; part of the blood from the right ventricle through the pulmonary artery by the ductus arteriosus into the aorta. Further, the blood flows in the foetus from the placenta by the umbilical vein, and its continuation the ductus venosus, to the vena cava and to the right side of the heart, and thence through the latter as just de- scribed, little or none going to the lungs, to the aorta, and so back by the umbilical arteries to the placenta. Such being the main features of the foetal circulation, with the inspiration of air and the separation of the infant from the placenta by division of the umbilical cord the fora- men ovale closes, the umbilical vessels, the ductus arte- p Left auricle. Left ventricle. Liver Portion of small intestine. [Kidney. Diagrammatic View of Foetal Circulation: a, arch of the acta : a', its dorsal part: a", lower end : ws, superior vena cava : vci, inferior vena where it join? the right auri- cle : vci', its lower end ; .".-, subclavian vessels: .;', right jugular vein": <\ common carotid arteries : tour curved dotted arrow-lines are carried through the aortic and pulmonary opening, and the auriculo-ventricular orifices : >la. opposite to the one passing through the pulmonary artery, marks the place of the ductus arteriosus : a similar arrow-line is shown passing from the vena cava inferior through the fossa oralis of the risrht auri- cle, and the foramen ovale into the left auricle : hv, the hepatic veins : vp. vena portse : X to vci, the ductus venosus : >n\ the umbilical vein : ua, umbilical arteries : uc, umbil- ical cord cut short : i, i , iliac vessels. MEDICAL JURISPRUDENCE AND TOXICOLOGY. 135 riosus, and the ductus venosus shrivel up, and, ceasing to be pervious, become fibrous cords. The blood then flows through the heart and lungs, and the adult circulation is established. Under ordinary circumstances, if the foramen ovale, ductus venosus, and ductus arteriosus are found open, the examiner would be warranted in stating that the foetus had not been born alive, and that, therefore, in all prob- ability, if any crime had been committed, it would be that of foeticide, and not of infanticide. Not unfrequently, how- ever, several days or even weeks may elapse before the blood ceases to flow through these vessels, and as the for- amen ovale may remain, under certain circumstances, open through life, obviously too much importance must not be attached to the open or closed condition of the heart and vessels as evidence of the infant having been born dead or alive. The drying- up of the part of the umbilical cord remaining attached to the umbilicus after division, that usually takes place within two or three days after delivery, together with its subsequent separation and cica- trization, may be regarded as proof of the child having been born alive, since, although the cord withers and dries up in a child born dead as well as in one born alive, it always remains attached in the former to the umbilicus, never separating spontaneously. The liver of the foetus is larger than that of a recently born infant, and that of the infant is larger than that of an eight or ten months old child. Liver and Contents of the Stomach in a New-born Cliild. — Too much importance, however, must not be attached to the size of the liver as positive proof of the infant having breathed, since the difference in the size of the liver in a recently born child, as compared with its size 136 A MANUAL OF at earlier or later stages of development, is only relative. The presence of milk or of farinaceous and saccharine articles of food in the stomach or intestine of an infant would be strong evidence that it had lived some time after birth. Unfortunately, the remains of food are not very frequently found in the alimentary canal of infants alleged to have been destroyed. In certain cases of infanticide it may become of importance to determine the age of the new- born child and the time that has elapsed since its death. Its age can approximately be determined by ascertaining if it presents all the characters of a fully-matured foetus that have already been described. It is not often possible to state exactly the time elapsing between the birth and death of an infant, as so many conditions have to be taken into consideration, such as the season of the year, the tem- perature, the character of the place, and the surroundings of the infant. Examination of the Mother : Signs of Recent Delivery. — In all cases of infanticide the reputed mother should be examined as well as the infant. The examination should be made as soon as possible, for, if delayed beyond a week or ten days, the woman may have so recovered as to pre- sent no signs of having been recently delivered. Should the examination be made within three or four days after delivery, pallor of the face and weakness will be noticed ; the skin will be found moist, soft, and relaxed ; the eyes somewhat sunken. The pulse is soft and usually quick. The uterus can be felt through the wall of the abdomen, which feels soft, and presents transverse livid lines, later becoming white and shining, and known as the linece albi- cantes. The breasts are full and knotty, and often exude a watery milk. The external genitalia are swollen, the vagina is capacious, the os uteri is low down, and the MEDICAL JURISPRUDENCE AND TOXICOLOGY. 1 ->7 niuco-sangumeous discharge from the uterus, known as the lochia, and characterized by its peculiar odor, is usually present. No one of these signs can be relied upon as proof that a woman has recently been delivered ; but, if they all be present together, they would constitute a very strong presumption of it. Should the woman have died shortly after delivery, not only would the signs just men- tioned be present, but in addition the uterus would be found enlarged, measuring between nine and ten inches in length ; its cavity lined with remains of the decidua and the point of attachment of the placenta marked by a gangrenous-looking spot. In all cases of infanticide, the mother not only endeavors to conceal the fact that she has given birth to a child, but more especially to conceal the body of the child. The concealment of pregnancy is not an offence in the eye of the law ; but the concealment of a birth, constituting a misdemeanor, renders the woman committing it liable to punishment. 1 As the woman, how- ever, who is convicted upon this charge is punished upon the ground of having concealed the body of the dead in- fant rather than upon that of having concealed its de- livery, she makes every effort to get rid of the child. Means of Committing Infanticide. — Among the different means made use of to destroy the new-born child may be mentioned suffocation, immersion in privies, strangula- tion, drowning, fracturing of the skull, burning, neglect, wounds, hemorrhage of the navel, exposure to cold, and poisoning. In fully four-fifths of cases of infanticide death is due to asphyxia in one form or another. Statis- tics show that fifty per cent, of infants criminally de- stroyed are suffocated, twelve per cent, immersed in privies, ten per cent, strangled, and live per ceut. 1 Tardieu : Etude Medico-legale sur P Infanticide, Paris, 186S, p. 99. 138 A MANUAL OP drowned. Infants are not unfrequently also destroyed by fractures of the skull and by neglect. Death caused by burns, wounds, hemorrhage of the navel, and exposure to cold occurs less often, however, in cases of infanticide, and in frequency in about the order mentioned. MEDICAL JURISPRUDENCE AND TOXICOLOGY. 139 CHAPTER XII. Legitimacy — Inheritance — Protracted Gestation — Premature Delivery — Viability — Procreative Power in the Male and Female — Impotence — Sterility — Tenancy by Courtesy — Paternity — Affiliation — Super- fee tat ion — Doubtful Sex — Hermaphrodism — Presumption of Death — Presumption of Survivorship — Personal Identity of the Living. Cases involving the questions of legitimacy and inherit- ance are not often decided by the testimony of the medical expert alone, the evidence necessary to prove that a child is the offspring of adultery being of another character. In all such cases, however, questions arise relating to the length of time in which gestation may be prolonged or shortened. Protracted Gestation. — The subjects of protracted gesta- tion and premature delivery having already been consid- ered in connection with the signs of pregnancy, it only remains to point out their bearing in relation to cases of legitimacy and inheritance. The law assumes that even- child born in wedlock is legitimate unless it can be shown that the husband and wife had been separated for a longer time than that accepted as the average period of gesta- tion, or that the husband was impotent. The difficulty, however, that would at once present itself in such a case is due to the impossibility of stating exactly what consti- tutes the accepted period of gestation. It is true that the average period of gestation is 280 days ; nevertheless, there are authenticated cases, as already mentioned, in which gestation was prolonged to 313 or even to 325 days, or delivery was premature, as at 210 to 217 days. But it must be admitted that the strongest possible evi- dence would be required to prove the legitimacy of a child 140 A MANUAL OF whose birth was shown not to have occurred until 313 days after the absence or death of the husband. Premature Delivery. — As regards the relation of pre- mature birth to questions of legitimacy and inheritance, there is no doubt that eight, seven, and even six months' infants may survive. 1 It has been stated that in very exceptional instances even a foetus but little over five months old may be viable. In cases, for example, where a living infant acquires the right of inheriting and transmitting property, the point that will have to be established is not whether the infant was viable in the sense that it would survive, but was it alive at the time of its birth, involving in turn the determination of what is meant by the expression being born alive. In a broad sense the foetus must be regarded as alive at any stage of its development ; the ovum, indeed, must be alive, since the embryo or foetus results from the development of a live ovum, not a dead one, impregnated by living sperma- tozoa. Leaving out of consideration, however, what might be regarded as merely metaphysical distinctions, as a mat- ter of fact that which constitutes a live birth will depend upon the significance attached to that expression by the law of the land, whatever that may be. In the United States and in England neither breathing nor crying is considered essential to establish the fact that a child was born alive. It is enough if the whole body has been brought into the world and the heart has throbbed, or if a movement of any kind has been made. In Scot- land and Germany crying, and in France respiration, is requisite. That crying should not be regarded as indispensable in proving a live birth is obvious, since 1 According to Haller (Elementa Pkysiologice, tomus octavus, Lausanne, 1778, p. 423) : "Ante septimum mensem foetus non potest superesse." MEDICAL JURISPRUDENCE AND TOXICOLOGY. 141 a child might be born alive, and yet peradventure it might be born dumb. 1 Tlie term bom alive or viable being so understood, medico-legally, it might be stated with perfect propriety that a foetus but six inches long, weighing only eight ounces, not more than four months old, was born alive, was viable — having moved its arms and legs, opened its mouth, etc. — though it died within half an hour of its birth. 2 The law assumes that a child born in wedlock is legitimate unless it can be proved that the husband was impotent — by which it is meant that he was physically incapable at the alleged period of concep- tion of begetting children. Impotence may be due to masturbation, to the opium and the alcoholic habit, diseases of the nervous system, blows upon the head and back, absence, deficiency, or malformation of the penis, as hypospadias, epispadias, fistula in perineo, castration, cancer or absence of the testicles, absence of spermatozoa from the semen, etc. In connection with the absence of the testicles it should be mentioned that their mere absence from the scrotum does not involve impotence, since such a condition may be simply due, as in cry psorch ides, to the testicles not having descended into the scrotum from the inguinal canal. Of the conditions causing impotence some are susceptible of treatment ; others are not. The procreative power in the male, or the age of puberty, begins at between fourteen to fifteen years of age, with the full development of the testicles, the power of fecundation depending upon the presence of active spermatozoa in the semen. The pro- creative power may continue to an advanced period of life, spermatozoa being found, as already mentioned, in the 1 Coke: Institutes, Philadelphia, 1S53, vol. i. 29b. ma. 2 British and Foreign Medical Review, vol. vi. p. 236. 142 A MANUAL OF semen of very old men. The impotence of old men ap- pears to be due to the sluggishness of their spermatozoa rather than to their absence from the semen. It should be mentioned that there may be impotency without ster- ility, as in those cases in which sexual intercourse is prevented by malformation of the penis; and, on the other hand, sterility without impotency, as in cases of castration. The procreative power begins in the female, as well known, earlier than in the male, at about from twelve to thirteen years of age, and even earlier in tropical countries. In the female, as in the male, unfruitfulness may exist without incapacity for sexual intercourse, and vice versa. Sterility in the female may be due to debility, leucorrhoea, dysmenorrhoea, amenorrhoea, menorrhagia, absence or dis- ease of the uterus or ovaries, imperforate vagina or hymen, occlusion of the uterus, etc. It is an interesting fact that while a woman may be sterile with one man she may be fertile with another, it frequently happening that a woman, married for years without issue, in contracting a second marriage may bear children. As the law regards a child as legitimate, though not conceived in wedlock, the mother marrying afterwards, and her condition being recognized by the husband at the time of the marriage, and as a child born after the death of its mother is legitimate, though the marriage-tie be dissolved by the death of the mother, it follows that a child, though conceived before marriage and born after the death of the mother — that is, neither conceived nor born in wedlock — would nevertheless be legally regarded as legitmate. Grounds for Divorce. — Impotence or sterility may con- stitute grounds for divorce proceedings on the part of hus- band or wife, provided it can be proved that the incapacity for sexual intercourse existed at or before the time of MEDICAL JURISPRUDENCE AND TOXICOLOGY. 1 \'-> marriage. If such incapacity supervened, however, after marriage, as due to disease, there would be no grounds for such proceedings. Tn such cases a medical examina- tion would, of course, be necessary, and while such an examination could not be made compulsory, any refusal on the part of either of the contending parties to submit to the same would certainly be injurious to the cause of the party so refusing. So-called " frigidity of constitution," or unwillingness to submit to sexual intercourse, would not constitute grounds for legal divorce, absolute proof being required of incapacity for sexual intercourse or of severe and intense pain being suffered by indulging in it, as in cases of vaginismus, etc. Tenancy by Courtesy. — In cases where a husband acquires a life-interest in the estate of his wife, a child having been born during the life of the latter, " tenancy by courtesy " as it is called, the medical examiner may be called upon to prove not only that the child was born alive, but also that it was born while its mother was living, in order that the child may inherit. The proofs of a live birth have already been considered. With reference to the legal qualification of a child having been born during its mother's lifetime the only difficulty that might present itself would be in the case of a child removed from its dead mother by the Cesarean section, in which instance, if the letter of the law was car- ried out, the husband would be debarred from inheriting. The interpretation of the clause providing that the child must be capable of inheriting will depend upon what the law chooses to regard as a monster — the latter not being capable of either inheriting or transmitting property. It is very difficult, however, to say what constitutes a monster legally. If a monster be defined as a creature 144 A MANUAL OF which has not the shape of mankind, 1 then a headless or double-headed or double-bodied creature would be excluded from inheriting. On the other hand, difficulty will be equally experienced in disposing of a property if a creature with two heads, with or without two bodies, be regarded as two individuals, and every creature with a single head, whether disomatous or not, as only one individual. 2 Paternity and Affiliation. — In connection with the sub- jects of legitimacy and inheritance, that of paternity and affiliation may as appropriately be considered here as else- where. The question of paternity presents itself under various circumstances, as, for example, in cases of bastardy, where the alleged father is compelled to support the child, or where a bastard child claims to be the heir of an estate, or where a child is born ten months after a second marriage, the woman having married a second time within a month of the death of her first husband. In such cases the paternity is determined by the likeness of the child to the parent, the color, features, attitude, habits, gestures, voice, personal de- formities being taken into consideration. In certain cases, questions of affiliation arise, as in the case of a woman having had intercourse with two men within a few days of each other and giving birth to a child, one of the men being affiliated as the father rather than the other. In connection with such cases, the medical examiner should bear in mind that, in the lower animals at least, the im- press of the first sire may be often seen in the foal begotten by the second one. In cases involving the capability of ^lackstone: Commentaries on the Laws of England, Philadelphia, 1877, Book II. p. 246. 2 St. Hilaire: Histoire general et particulaire des Anomalies de I' Organi- sation chez l' Homme, Bruxelles, 1837, tome iii. p. 331, MEDICAL JURISPRUDENCE AND TOXICOLOGY. 145 inheriting and transmitting property, the' question of superfcetation, or the possibility of a woman conceiving a second time when already pregnant, may present itself. Superfcetation. — In cases of superfcetation either two chil- dren are born at the same time, one of which, however, is immature, or two children are born at different times, both of which are mature cases of superfcetation of the first kind. Superfcetation may be explained on the supposition that there has been a twin conception, one of the embryos, however, developing more rapidly than the other ; or that the uterus was double, as is always the case in the marsupial animals, like the kangaroos, etc. Cases of the second kind can, however, only be explained by supposing that the woman had sexual intercourse with one or two different men and conceived successively. That superfcetation may be due to repeated sexual intercourse and to successive conceptions there can be no doubt; there are well-authenticated cases of a woman having given birth to children of different colors as the result of intercourse with a white and a black man successively. It is also well known that double concep- tion occurs in animals — a mare, for example, covered successively by a horse aud an uss, giving birth to a horse and a mule. Double Sex : Hermaphroditism. — Not infrequently, on ac- count of divorce proceedings, questions in regard to legiti- macy of offspring or capability of inheriting, etc., the atten- tion of the medical examiner is called to individuals in whom the sex is doubtful, or who are said to be hermaphrodites. While, as a general rule, there is no difficulty in distinguish- ing the sex in such cases, nevertheless, on account of the manner in which external and internal generative organs develop in certain exceptional cases, it becomes very difficult, if not impossible, at least during life, to state positively 10 146 A MANUAL OF whether an individual is a male or a female. At an early period of intra-uterine life, at six weeks or thereabouts, it is impossible to determine the sex of the embryo. The external organs of generation are as yet undeveloped, and Fig. 37. Diagram of the Wolffian bodies, Mullerian ducts, and adjacent parts previous to sexual distinction (as seen from before) : sr, the suprarenal bodies ; r, the kidneys ; ot, common blastema of ovaries or testicles ; W, Wolffian bodies ; w, Wolffian ducts ; m m, Mullerian ducts ; gc, genital cord ; ug, sinus urogeni- tals ; i, intestines ; cl, cloaca (Quain). the internal organs consist (Fig. 37) of what may be called two indifferent bodies, the ducts of Muller and the Wolffian bodies. In case of such an embryo developing into a male, the two indiffereut bodies will become testicles, which, in descending, push the abdominal walls ahead of MEDICAL JURISPRUDENCE AND TOXICOLOOY. 147 them, giving rise in this way to the formation of the scrotum, which they ultimately occupy. The Wolffian bodies are transformed into the epididymis, vas deferens, etc., the ducts of Miiller becoming atrophied. On the other hand, should such an embryo develop into u female, the two indifferent bodies would become ovaries and remain in the abdominal cavity, and the ducts of Miiller would be transformed into the vagina, uterus, and Fallopian tubes, the Wolffian bodies becoming atrophied. The penis and clitoris, developing later than the internal generative organs, consist essentially of the same parts, the only difference between them being due to the fact that the two folds of skin which remain distinct, as the labia minora in the female, grow around and underneath, as the skin of the penis in the male ; while the two cutaneous folds constituting the labia majora of the female, in fusing together in the middle line, form the scrotum in the male. Such being the development of the generative organs, it is readily seen, on the supposition that an individual is really a male, that, if the testicles in such a case were to remain in the abdominal cavity, the labia majora and minora failing at the same time to coalesce in the middle line, and the penis to remain undeveloped, such an indi- vidual might be easily mistaken for a female. On the other hand, if the clitoris, a highly erectile organ, was very much developed, and permitted sexual intercourse, such an individual might be considered a male, it being supposed that the testicles had not descended ; the absence of a scrotum being in that way explained. 1 It is obvious, from what has been said, that a true human hermaphrodite, that is a human creature in which a full functionally complete set of organs are united in one 1 Beck : op. cit., vol. i. pp. 169, 170, 172, 175. 148 A MANUAL OF individual, is a physical impossibility. For, even on the supposition that the Mullerian ducts and Wolffian bodies would be simultaneously transformed into vagina, uterus, epididymis, vasa deferentia, etc., one of the indifferent bodies into an ovary, the other into a testicle, a penis would not be developed simultaneously with a clitoris, since being essentially one and the same structure one or the other is alone developed. That the clitoris and the penis are essentially homologous organs is still further proved by the fact that urination is accomplished by the clitoris in the female of certain animals, rodents, and others exactly as by the penis in the male of the same species. It need hardly be added that, while there is no authenticated case proving that a true human hermaphrodite has ever existed, such a disposition of the generative apparatus not unfre- quently occurs among the lower animals, as snails, tape- worms, etc. In cases where an estate descends to the first-born male, if the offspring should be of doubtful sex, the peculiarities constituting the individual a male would have to be de- termined by the medical expert. In such doubtful cases the decision might be postponed until the child arrives at the age of puberty, when the secretion of healthy active spermatozoa would establish the sex. It is important, with reference to the attaining of majority, that the exact day and hour of a child's birth be accurately noted — a person attaining a legal majority the first instant of the day before the twenty-first anniversary of his or her birth-day, though forty-seven hours and fifty-nine minutes less than the com- plete number of days, counting by hours on the principle that a part of a day is medico-legal ly equal to the whole of a day. 1 1 Taylor : op. cit., p. 599. MEDICAL JURISPRUDENCE AND TOXICOLOGY. 149 Presumption of Death. — It not uii frequently happens that a person leaves his home and is not heard of for many continuous years, perhaps never again. The law presuming such a person to be dead, the executor is justified in settling the estate. The length of time usually assumed legally as warranting the presumption of death is seven years from the time the person was last seen or heard of. 1 A woman who had not heard of her husband for that number of years might marry again, therefore, without rendering herself liable to the charge of bigamy, even if it was afterwards shown that the first husband was living at the time of the second mar- riage. In cases where property is inherited, and in life- insurance cases, so long a time as seven years is not usually considered necessary by the courts, settlements being often made in two years of the period within which the person was presumed to have died. The presumption of death is usually determined by a jury on the general evidence submitted. Under certain circumstances, however, as in cases where the person presumed to be dead was suffering from some disease at the time last seen or heard of, medical testimony would be taken as to the probable issue in such a case. Presumption of Survivorship. — When several persons, members of the same family, for example, are lost at sea or are burned in a fire, the law usually assumes that they perished together. But, in the disposition of an estate thus left, it may be a matter of difficulty to de- termine who is the heir-at-law, and medical testimony may be taken to aid in determining what member of the family, if any, survived the others. Suppose that the persons dying were father and son, and that the son 1 Beck : op. cit., vol. i. p. 643 ; Tidy : op cit., part i. p. 385. 150 A MANUAL OF survived the father, even though it were for a moment, the wife would inherit. Suppose that two persons were related to each other as testator and legatee, and that the latter should die first, the legacy would then lapse. If, however, the legatee survived the testator, then his heirs would in- herit. A husband, as already mentioned, inherits from his wife if their child survives the death of the mother, even for only a moment. While no positive statements can be made by the medi- cal examiner in cases involving the presumption of sur- vivorship, there are, nevertheless, certain general probabili- ties that should be taken into consideration. Thus, for example, if a number of persons of different ages perish together, it would be a fair presumption that the very old and very young, other things being equal, would not sur- vive as long as those of middle age. In the case of a man and woman being drowned, it is to be presumed that, on account of greater physical strength, the man survived longer than the woman. Young people and old persons appear to succumb more quickly to the effects of cold than adults. The latter, however, do not resist the effects of heat as well as the former. As regards the effects of cold and heat upon the human system, more particularly in reference to questions of survivorship, the general physical condition, the kind of clothing, the extent to which alcohol has been indulged in, would have to be taken into consid- eration. It is well known that the aged can do without food better than the young. In cases of death from star- vation, the presumption would be, therefore, in favor of the former surviving rather than the latter. Personal Identity of the Living. — In cases involving the inheritance of property, medical testimony is occa- sionally taken in identifying a certain individual as the MEDICAL JURISPRUDENCE AND TOXICOLOGY. 151 rightful heir — the evidence upon which the identification depends being the presence of scars, deformities due to fractures, etc. Similarly, in cases of assault or of robbery, the assailant must be identified. As the identity of a per- son, whatever the nature of the case, civil or criminal, is usually established by the members of the family, friends or acquaintances, and not by a physician, it is unnecessary to dwell upon the subject of the personal identity of the living. In this connection it may be stated, however, that among the more important means of identification may be men- tioned the size of the person, the dress, kind of voice, the presence of moles, scars, deformities, cicatrices, naevi, tattoo marks, etc. 1 In relation to the subject of personal identity, a few words with reference to the distance at which per- sons can be seen and sounds heard do not appear inappro- priate. A man of ordinary height may be seen on a clear day and on level ground at a distance of from two to three miles, though not necessarily recognized. The recognition of a person depends not only upon being seen, but upon the appreciation of the peculiarities afforded by his size, gait, complexion, color of hair and eyes, etc. Even the best known persons are not always recognized at a distance of one hundred and nine yards; less well-known ones not being recognized even though but thirty yards away. Well- known persons cannot be recognized in the clearest moonlight twenty yards away, and by starlight at a distance exceed- ing twelve feet, though the light from a flash of light- ning or from a pistol-shot may enable a person to recognize another as a thief or an assailant. The distance at which sounds cau be heard, such as the report of a gun or a pis- tol, being dependent upon the condition of the atmosphere, 1 Woodman and Tidy: op. cit., pp. C39-641. 152 A MANUAL OF moisture, direction of the wind, is too variable to be posi- tively stated. As well known, however, the velocity of sound being at mean temperature about 1130 feet in a second, if a flash of light is seen and a report is heard afterwards, on the supposition that they were simultane- ously produced, the distance separating the person who fired and the one hearing the report can be calculated. MEDICAL JURISPRUDENCE AND TOXICOLOGY. 1 -h\ CHAPTER XIII. Feigned Bodily Diseases — Hypnotism — Life Insurance — Medical Mal- practice — Medical Registration. Feigned bodily diseases very frequently demand the attention of the medical examiner, especially in the cases of soldiers, sailors, and prisoners, who resort to any and every pretext to shirk their duties ; and of civilians, who hope in this way to avoid serving on juries, appearing as witnesses, or to escape military service. It is almost incredible what malingerers will resort to in order to ac- complish their purpose, indulging in the most disgusting performances : swallowing feces, urine, blood, mutilating themselves as occasion may require. Disease is sometimes simulated by simply lying, or by mimicry, or cunning ; at other times by the aid of trusses, splints, bandages, spectacles, crutches, and such means. The motives in- ducing a person to simulate disease are usually fear, gain, laziness, notoriety. Thus, for example, it is not unusual, especially abroad, where military service is compulsory, for such as are liable to cut off a finger, break a tooth, or put out an eye, to avoid conscription. The hope of gain is a very common motive, as in the attempts so often made to obtain damages for injuries incurred in railroad accidents. Beggars and others, to escape work and to get into hospitals or almshouses, often feign disease. Hysterical persons, especially women, will stoop to every kind of deceit, and submit even to harsh treatment, through a pure love of notoriety. While there is no kind of dis- ease or injury which malingerers will not simulate in order 154 A MANUAL OF to accomplish their purpose, whatever that may be, among the most common of these may be mentioned the feigning of fever, heart disease, consumption, hsematuria, inconti- nence of urine, epilepsy, paralysis, catalepsy, deafness, dumbness, blindness, tumors, wounds, etc. 1 All such cases of malingering demand the greatest patience and tact on the part of the medical examiner. Not only one but several visits may be required before the examiner can be satisfied that the case is one of malingering. The visits should be paid at an hour when the suspected person is least likely to expect them. The parts of the body said to be diseased or injured should be examined unclothed, thoroughly exposed, all dressings and bandages being re- moved. No attention or importance should be attached to the statements of either the person supposed to be ma- lingering, or of his relatives or friends. The prescribing of some disagreeable medicine, or the suggestion of using anaesthetics, and performing a dangerous operation, may sometimes frighten the individual into confessing im- posture. 2 In some obstinate cases, however, all means, even of a severe character, fail to elicit confession. Relation of Hypnotism to Crime. — The question of the possibility of a crime being committed by an individual when hypnotized at the suggestion of another, and the responsibility so incurred by one or both, is still one of discussion. It is true that experiments have been made which show the remote possibility of crime being com- mitted under such circumstances, as in the case, for example, 1 Malingerers appear to have been as common in ancient as in mod- ern times. Even so far back as tbe time of Galen rules were given for the guidance of the physician in detecting such frauds {London Med. Gazette, vol. 17, p. 989). 2 Zacchias : op. cit., Lib. iii., Tit. ii., Quaest. ii., p. 288. MEDICAL JURISPRUDENCE AND TOXICOLOGY. 155 of a hypnotized woman at the command of another plunging a dirk into a manikin dressed up as a woman. But it must be admitted that there is no evidence whatever that a murder has ever thus taken place. 1 In hypnotized persons, women especially, hysteria constitutes so important a factor, and hysteria is so often simulated, that it would become difficult if not impossible for the medical examiner to state positively to what extent a woman acting in the manner just described should be held responsible. Life-insurance. — A life-insurance may be regarded as a contract, the deed being termed a policy, whereby a company, in consideration of a premium paid in instalments or in a lump sum, agrees to pay a definite sum to the heirs of the insured at death, or at some definite period of life. In the case of the former, the amount insured for being pay- able only at death, it becomes incumbent upon the heirs to prove most positively, and to the entire satisfaction of the company, that the insured person is actually dead. For example, in cases of persons who have disappeared, who went to sea and were never heard of again, questions as to presumption of death or of survivorship may demand the attention of the medical examiner. The question as to the general health of an applicant for a policy of insurance, the tendency to disease through inheritance, alcoholism, excessive use of tobacco, or other causes, is that which brings the medical profession in the most intimate relation with the insurance companies. In almost all the lawsuits 1 The attention of the writer has been called to two cases of murder, as reported in the daily papers, in which it was alleged that the defence offered was that the accused had committed the crime, when hypno- tized, at the instigation of the hypnotizer. In one case the hypnotized was adjudged innocent of the crime of murder, the hypnotizer guilty. 156 A MANUAL OP in contested life-insurance policies the points contested are with reference to what was actually meant by certain medical terms, such as diseases, habits tending to shorten life, etc. It is astonishing what a difference of opinion prevails among even intelligent people as to what constitutes a tem- perate person, many an individual who takes several drinks of brandy or whisky a day considering himself per- fectly temperate, and so stating to the medical examiner, utterly unconscious of his health being gradually under- mined, and of his life being shortened by the daily use of alcohol. It is due to such a difference of opinion as to the effect of alcohol upon the system that the question of in- temperance has given rise to so much discussion in cases of life-insurance. While it is undoubtedly true that there have been exceptional instances of individuals enjoying good health and living to a good old age who had been in the habit of drinking, and more particularly whisky, all their lives, nevertheless it cannot be denied that, as a general rule, the habitual use of alcohol in perverting nutrition induces disease of the heart, liver, and kidneys, and so tends to shorten life. It should be mentioned, however, that if the habits of the individual at the time of insurance were temperate, the fact that intemperance was subsequently developed would not debar the heirs from recovery upon the policy. What has just been said of the use of alcohol with reference to the shortening of life applies equally to the influence of the morphia habit. The concealment of the fact that an applicant for a policy of life-insurance was an opium-eater at the time of application would justify the company in refusing to pay the heirs the insurance. There is no doubt that insanity also tends to shorten MEDICAL JURISPBUDENCE AMD TOXICOLOGY. 157 life, and with the view of avoiding future complications which might arise upon this point, every insurance policy should contain a direct question on insanity; the insurance company reserving to itself the privilege of insuring or not, according to the particular circumstances of the case. Litigation in cases of life-insurance not unfrequently arises in consequence of the insured person committing suicide after the taking out of the policy. Under such circumstances a company would certainly be justified in refusing to pay the insurance, if it could be proved that the suicide was committed with the intention of paying off debts or leaving money to the heirs. If, however, the suicide was due to insanity, clearly developed after the policy had been taken out, the heirs would undoubtedly be entitled to the payment of the insurance. From what has just been said of the relationship of the alcohol and opium habit, insanity, suicide, to life-insurance, it is obvious that, for the interest of the company, as well as for that of the insured, a most thorough examination should be made as to the health of the individual at the time of the application for the policy. Not only should all the printed questions of the policy be satisfactorily answered by the applicant, but the latter should be most carefully questioned orally by the medical examiner of the company. It is the concealment of the true state of the health of the applicant, either fraudulently or unintention- ally, at the time that the policy was taken out, which gives rise to most of the lawsuits in cases of life-insurance. Medical Malpractice. — Actions for damages for large amounts are so often brought against physicians on the charge of malpractice, that it is well for the medical pro- fession to realize that the law affords, even to the most dis- tinguished of its members, under such circumstances, no 158 A MANUAL OF especial protection. In order, therefore, to avoid the annoy- ance and loss of time always entailed by such suits, howso- ever they may terminate, it is most important that practi- tioners should never guarantee or contract to effect a cure, even in the simplest kind of cases. Whatever the nature of the difficulties arising in the case may have been, however improbable that they should have occurred, or that they could have been foreseen, is immaterial, the law not accept- ing any such excuses for the failure on the part of the prac- titioner to fulfil his contract to cure. Such being the case, how unwise would it be for a surgeon to promise that he will cure a deformity when the operation involved may be followed by pyaemia and death ! or for the gynaecologist to guarantee the safe re- moval of an abdominal tumor when there is always a risk that a fatal peritonitis may follow the operation ! All that a practitioner can be expected to say is that he will do the best he can for his patient. The law only demands that he will exhibit in the practice of his profession a fair and competent degree of skill. It must be admitted, how- ever, that it becomes difficult, if not impossible, to say, under certain circumstances, just what constitutes legally a reasonable or ordinary amount of professional skill. It is evident that the skill indispensable to the success of a physician or surgeon practising in a metropolis must be far greater than that demanded of one practising in a village. The legal term ordinary skill is, therefore, far from being a definite one, and from the very nature of the case must have a varied application. Not only ordinary skill, such as is demanded in the successful performance of a surgical operation, must be exhibited, but ordinary care and attention in the after-treatment must be paid the patient as well. The bandaging, the dressings, the diet must be all care- MEDICAL JUEISPRUDENCE AND TOXICOLOGY. 159 fully looked after, as neglect of the same, involving possibly the occurrence of secondary hemorrhage, morti- fication, pysemia, or even only deformity, will render the practitioner justly liable to a suit for damages. On the other hand, a practitioner should not be held responsible for not prescribing some particular remedy or for the failure of some one remedy to cure, since the greatest difference of opinion prevails among therapeutists as to the efficacy of all so-called " remedies." It is still a question among medical jurists whether a practitioner renders himself liable to prosecution in deviating some- what from the usual manner of performing an operation, as, for example, in vaccinating on some part of the arm other than the part usually selected for that purpose. As a matter of fact, it may be mentioned, however, that in one instance in which the virus was introduced nearer to the elbow than usual and serious inflammation followed, the court ruled that the attending physician was responsible for all the bad consequences attending the case. As the law recognizes no particular school of medicine, homceopathists, eclectics, botanists, herb doctors have about the same stand- ing legally as regular members of the profession. Every practitioner is supposed, however, to practise according to the system of medicine taught in the school of which he is a graduate. It might be supposed, therefore, that if a vio- lent remedy was administered or a surgical operation per- formed, by an individual who had received no medical education whatever, in the event of serious consequences, death ensuing, the law would hold such a person crimi- nally responsible. But, strange to say, there have been cases, as, for example, when a prolapsed uterus, being mis- taken for a placenta, was torn out by a midwife and a fatal hemorrhage ensued ; and yet the court ruled that 160 A MANUAL OF there was not sufficient evidence to convict the prisoner of the crime of murder, and he was acquitted. It is to be hoped, since the law, in Pennsylvania at least, requires the registration of all physiciaus, that any one convicted of practising medicine without the diploma of a reputable school will be summarily dealt with. Medical Registration. — In this connection, for the benefit of young physicians just beginning the practice of their pro- fession, it does not appear superfluous to quote the full text of the registration law : " It shall be the duty of every prac- tising physician and of every practitioner of midwifery, on or before the first day of July next ensuing (the day on which the law goes into eifect), to report his, her or their names and places of residence to the health officer at the office of the board of health, and it shall be the duty of the health officer to have the same properly registered in index form in suitable books. In the event of any of the persons above specified removing to any other place of residence, it shall be their duty to notify the health officer of the fact within thirty days after such removal, except where the persons removing shall cease to act in such official capacity as makes them subject to the provisions of this act." Suits brought against physicians for malpractice are usually for damages — civil rather than criminal in char- acter. By far the greater number of such cases are purely for the purpose of black-mail, the plaintiff usually securing the services of counsel with the understanding that if he wins the suit, his fee will be part of the damages awarded. Among such cases may be mentioned those in which a shortening of a limb, the stiffness of a joint, a certain deformity are alleged as having been due to the neglect of the surgeon in the treatment of a fracture or of a dis- location. In all such cases it is incumbent upon the MEDICAL JURISPRUDENCE AND TOXICOLOGY. 161 plaintiff to prove that the alleged injury or disease; was due to the attending surgeon, and that the same might have been foreseen and avoided by proper treatment. Malpractiee can only be proved when it is shown that the practitioner has set aside established principles and neglected to make use of means universally held by the profession to be necessary in a given case. It must be shown, however, that in all probability the treatment according to such established principles would accomplish the desired end, that such treatment never proves detri- mental, and that it is sanctioned by the general practice of the profession. It should be mentioned in this connection that gratuitous- ness will not exempt a practitioner from a charge of mal- practice if it can be proved that his treatment was im- proper, or that he neglected the patient. On the other hand, a patient who refuses to co-operate with his physi- cian cannot recover damages for any injury so sustained, unless the latter can be shown to have been due to mal- practice. As it has been decided that a physician who takes with him, to a confinement case, any one except a physician or a student of medicine, renders himself liable for damages; except in cases of necessity, it would be well under any circumstances for him to obtain the consent of the patient before introducing a stranger into the sick- room. In connection with the general subject of medical mal- practice it may be mentioned that apothecaries render themselves liable to suits for damages or even to criminal prosecution, if it can be shown that, through their igno- rance or carelessness, or that of inexperienced clerks in the putting up and selling of medicines, serious or fatal con- sequences ensued. 11 162 A MANUAL OF CHAPTER XIV. Insanity — Varieties of Insanity — Idiocy — Mania — Dementia — Medico- legal Relations of Insanity — Criminal Responsibility — Medico-legal Terms in Insanity — Feigned Mental Diseases. Insanity. — The subject of insanity has so extensive a range as to render it impossible within the limits of this work to do more than indicate its salient features, more especially from a medico-legal point of view. Every practitioner should appreciate the importance of the fact that at any moment he may be called upon to visit a person said to have lost his reason, and should be qualified, there- fore, to express an opinion as to his sanity. Fig. 38. Fig. 39. Idiocy (Feeeiee). Epileptic Mania (Fereiee). Varieties of Insanity. — Systematic writers upon the sub- ject of insanity differ very much in the manner in which MEDICAL JURISPRUDENCE AND TOXICOLOGY. 1 63 they classify the different varieties of insanity. For our present purpose insanity may be conveniently regarded as being of three kinds — Idiocy or Amentia, Mania, and Dementia. 1 Insanity - Amentia ( Imbecility 1 Ic Idiocy Mania Proper Melancholia Partial Intellectual Moral Partial Moral Kleptomania Pyromania Dipsomania Homicidal Suicidal Puerperal Dementia — Paralytic (Paresis) Mania Idiocy (Fig. 38) differs from all other kinds of mental disease in being congenital, depending upon an arrest of cerebral development. There are various degrees of it, vary- ing from a condition in which there is an entire absence of mind to one in which there is a glimmering of intelligence, as in imbecility. Imbeciles are usually docile, and, in some instances, can be taught, by careful management, to talk and even to read. The causes of idiocy are usually syphilis, intemperance (of the parents), consanguineous marriages. Idiots can generally be recognized by the small size of the head (except in the case of congenital hydro- 1 Ray, I. : A Treatise on the 3ledical Jurisprudence of Insanity, fifth edition, 1871, pp. 84, 430, 577 ; Georget : Be la Folie, Paris, 1820, p. 101 ; Mandsley, M. D. : Physiology and Pathology of the Mind, London, 1868, p. 253. 164 A MANUAL OF cephalus, in which the head is very large), thickness of the lips, enlargement of the tongue, salivary glands, and tonsils, vaulting of the hard palate, irregularity of the teeth, with tendency to decay, deficiency of the lobules of the ear, de- fective vision, weakness in the fingers and thumbs. Idiots are not only characterized by the absence or deficiency of intellectual power, but also by undue development of the animal part of their nature, as shown by their filthy habits, gluttony, etc. Upon post-mortem examination, the convolutions and fissures in the brain of an idiot are usually found less numerous and less complicated in their arrangement than in the brain of an intelligent person. Together with the deficiency of the gray matter of the cor- tex, due to so simple a type of brain, important parts of the latter, such as the basal ganglia, corpus callosum, cerebellum, may be undeveloped or even entirely absent. Neither idiocy nor imbecility is likely to be mistaken for mania or monomania, for, although the intelligence in the latter conditions is perverted and irregular, hallucinations being common, there is not that entire absence of it which is so characteristic, of idiocy. However, as we shall see presently, idiocy, in some respects, resembles dementia. It need hardly be added that idiots are entirely irrespon- sible, both from a civil and criminal point of view. Mania (Fig. 39) is understood as a general perversion of the mental faculties, accompanied usually with more or less excitement, which in certain cases may amount even to fury. The reasoning powers are not absolutely lost, but are rather confused, disturbed, disordered. There is no orderly sequence of thoughts; ideas follow each other without any relationship. At one moment the maniac may be tractable, pious in his expressions, singing hymns ; at another ungovernable, abusive, blasphemous. He sings, MEDICAL JURISPRUDENCE AND TOXICOLOGY. 165 (lances, laughs, then cries, tears off his clothes, breaks any- thing that he can lay his hands on, often at such times exhibiting great strength. The skin is dry and hot; the eye has a very characteristic expression, a fixed, wild, bril- liant sort of stare. The pulse and respiration arc usually quick and the temperature high. The appetite is generally voracious. The urine and feces are often voided involun- tarily. Sexual desire is usually increased, and when so occurring in women is known as nymphomania; in men as satyriasis. One of the most striking features of mania is the total alteration wrought in the feelings of one so affected towards the members of his family; the maniac becoming suspicious of and hating those whom he had formerly naturally loved. When haunted by delusions, which is not unfrequently the case, he may become so dangerous as to necessitate physical restraint. Systematic writers upon the subject of insanity consider mania to be of different kinds, distinguishing the varieties, as mania proper or intellectual mania, which we have just described, melancholia, partial intellectual mania, moral mania, partial moral mania, kleptomania, pyromauia, dipsomania, and homicidal, suicidal, puerperal mania. But, whatever views may be held by systematists concerning dif- ferent kinds of insanity, moral, emotional, intellectual, etc., it should be understood that the law recognizes only one kind of insanity — that which affects the mind, the latter being adjudged as unsouud when affected with delusions that cannot be dispelled. Melancholia may be regarded as a variety of mania, differing more especially from the latter in being charac- terized by depression rather than excitement, by the patient refusing food rather than partaking of it eagerly. The face is pale and pinched, the eyelids droop, the pupils are 166 A MANUAL OF dilated. The patient sits for hours at a time doing noth- ing, brooding over melancholy thoughts ; he is often of a religious nature, suspicious of being persecuted, burned, poisoned, etc., often dirty in habits, soiling his clothes and linen, utterly indifferent to his personal appearance. Partial intellectual mania is characterized by the fact that the person who suffers from this form of mental dis- ease is possessed of some one notion contrary to his own experience, as well as to all common sense. He may imagine that his stomach is full of lizards and snakes; or, if the individual be a woman, that her uterus contains hydatids, and that she is pregnant by the devil, as was believed in a well-known case. 1 As it is still a question whether there is any such form of mania as moral mania, that is, of a morbid perversion of the natural affections, temper, and habits of an individual without any noticeable derangement of the intellect, 2 it is only necessary, in this connection, to say that no sudden outburst of this form of mania should be admitted as ex- cusing or palliating any crime. There are no well-authenti- cated cases, for example, of persons becoming suddenly affected with an insane desire to commit murder, and unless it can be clearly shown that, previously to the commission of such a crime, the defendant had given evidence of being insane, the plea of moral insanity should not be enter- tained by the court, but the defendant should be punished to the full extent of the law. Kleptomania, or the disposition to steal, is exhibited so often by persons in good circumstances that this peculiarity cannot 1 Esquirol, E. : Des Maladies mentales, tome premier, Paris, 1838, p. 495. 2 Pritchard: Treatise on Insanity, 1837, p. 16; Pinel: Traite medico- philosophique sur I' Alienation mentale, deuxieme edition, Paris, 1809, p. 155. MEDICAL JURISPRUDENCE AND TOXICOLOGY. 107 be attributed to want, but to some aberration of the intellect. In all trials of kleptomaniacs, it must be proved that the defendant is incapable of appreciating what constitutes the crime of theft; otherwise the plea of this form of insanity would be the favorite defence of all professional thieves. Pyromania, or the insane desire to set fire to anything, barns, dwelling-houses, churches, is a less common form of mania than kleptomania. It appears to be ofteu associated with epileptic insanity. No doubt this form of mania, like the so-called " moral mania," is made a convenient plea for the defence of crime, as in cases of arson. Dipsomania, or the craving for drink, differs from the desire for liquor shown by those who indulge daily in the use of alcohol in the circumstance that it is followed by long remissions in the thirst for it. During these periods there is not only no desire, but often a loathing, for it. With the return of the craving, the individual will literally soak himself with spirits for days and weeks at a time, often secluding him- self and shunning society of all kinds. In this connection, the responsibility of drunkards may be as appropriately considered here as elsewhere. Undoubt- edly, irresponsibility would be inferred by the law in the case of a person whose mind had been weakened by habitual drinking, unless it could be shown that, at the moment of the commission of an act — such as the signing of a deed — the individual was fully conscious of the nature of the contract. A murder committed by a drunken man would not be excused, however, by the law, if he had got volun- tarily drunk before perpetrating the crime. If it could be proved, however, under such circumstances, that his mind had been hopelessly diseased by drink, he would be held irresponsible. In all such trials, an extenuating circum- stance would be the fact that the defendaut had no grudge 168 A MANUAL, OF or malice against the deceased, but Lad committed the murder when under the influence of drink. It may be mentioned, in connection with the responsibility of drunk- ards, that somnambulists cannot be held responsible for their acts, for, in such a condition as that of somnambulism, there can be, from the very nature of the case, no motives to commit crime, the intellect being in abeyance. Homicidal mania is characterized by an irresistible impulse to commit murder. In instances of this kind of insanity, it will be generally learned, from the previous history of the case, that the individual had been injured at some previous period, as by a fall upon the head, in consequence of which he had become more or less morose and melancholic at times. The maniac may murder a number of persons at once, the victims, not unfrequently, being members of his own family, to whom he had been previously devotedly attached ; there is an entire absence of motive to commit the crime. Further, the maniac makes no effort to escape from the consequences of his act, as an ordinary sane murderer would do. He may even boast of what he has done, saying that he had been directly inspired to do what he did. Suicidal mania, known also as monomania, is exhibited in the disposition to take one's own life. While, in most cases of suicide, the verdict of the coroner's jury — the latter actuated, no doubt, by kindly feelings for the family of the deceased — is death by his or her hands while labor- ing under temporary insanity, there can be no doubt that perfectly sane persons commit suicide. In ancient times it was a common custom for persons who were at war to take their own lives rather than take the chances of falling into the hands of their conquerors and run the risk of torture and death. It is a matter of everyday occurrence for MEDICAL JURISPRUDENCE AND TOXICOLOGY. 169 men who have failed in business to commit suicide rather than to face their creditors, disaster, and financial ruin. Indeed, so many suicides are committed, not only intention- ally, but intelligently, that it becomes very often difficult to say that the self-destruction was due to insanity. The disposition to commit suicide is, in many instances, un- doubtedly inherited, inasmuch as it is well known that the members of certain families for generations have been in the habit of taking their own lives. A remarkable feature in suicide is the regularity with which it occurs, and the frequency with which it is committed in the same way. Indeed, under certain circumstances, the perpetration of the act and the uniformity of the means by which it is accomplished may not inappropriately be said to be epidemic. 1 Puerperal insanity, which is one of the most distressing kinds of mania, attacks women after delivery, within a period varying from a few days to several weeks. It occurs usually before the stoppage of the lochia ; albu- min appears in the urine, and the flow of milk is sup- pressed. A woman suffering from this form of mania may be either foul-mouthed or taciturn and pious in her talk, and may often be troubled with religious delu- sions. She may either totally neglect her infant, or take such a dislike to it that she sooner or later destroys it, and frequently in the most horrible manner. It should be remembered, therefore, by the medical jurist, that, in certain cases of infanticide, the mother may have been afflicted with puerperal insanity, and that under such cir- cumstances she should not be held responsible for the con- sequences of her actions. 1 Buckle : History of Civilization in England, chap. i. p. 25 ; Morselli, H. : Suicide: An Essay on Comparative Moral Statistics, Kew York, 188:2. 170 A MANUAL OF Dementia (Fig. 40), beginning with a simple enfeeblernent of the intellect, terminates with an entire extinction of the Fig. 40. Dementia (Paresis) (Ferrier). mental powers. This form of disease is characterized by absence of ideas, accompanied by depression, rather than, as in mania, by exaggerated mental activity, with excitement. It may follow acute mania or melancholia ; is often due to disease of the brain, the result of injury, and is frequently incidental to old age. The countenance in dementia is pale, and the expression is a peculiarly vacant one. A most striking feature is loss of memory, the patient, in an advanced stage of the disease, forgetting even what has transpired within a moment or two. Individuals affected with this disease act in an undecided, silly, childish manner, repeating themselves in conversation, appearing neither to like nor dislike their former friends and associates, moving about in an aimless, listless way. A disposition is often exhibited in this disease to hoard up articles of no value. Paralytic dementia, also known as general paralysis or paresis of the insane, appears to be due more especially to MEDICAL JURISPRUDENCE AND TOXICOLOGY. 171 disease of the gray matter of the convolutions of the brain. This form of disease may be caused by syphilis, alcoholism, excessive mental work. The first symptoms of general paresis of the insane arc a certain fretfulness, irritability of manner, accompanied by carelessness in dress, etc. The patient becomes deluded with the idea of being possessed of great wealth or great physical strength. As the disease advances, the muscular power becomes much weakened, and the gait unsteady. The tongue trembles when protruded, the. lips are tremulous, and difficulty is experienced in pronouncing certain words. Vision becomes affected. A bloody, gelatinous-like swelling of the ear develops, the so-called " hsematoma aims," the contents of which, resembling the extravasations under the dura mater in pachymeningitis, appear to be due to a degeneration of the branches of the carotid artery. The prognosis in general paresis of the insane is always un- favorable, death taking place within a period varying from two to ten years. Medieo-Legal Relations of Insanity. — Having de- scribed, in a geueral way at least, the most important forms of mental disease, it remains now to consider them in their medico-legal relations. Should a per- son be determined to be insane, the first question to be considered is as to the decree of the insanity, and more especially as to the civil and criminal responsibility of the individual. As out of this twofold inquiry arise all medico-legal questions of insanity, there should be no misunderstanding as to what is meant by civil and criminal responsibility. Civil responsibility implies the capability of managing one's own business, taking an intelligent part in the ordinary affairs of civil life, making contracts, wills, etc. Criminal responsibility 172 A MANUAL OF renders the perpetrator of any crime, such as theft, arson, murder, liable to punishment, supposing the person suf- ficiently sane at the time of the commission of the deed to be held responsible. In all cases of insanity the practitioner who assumes the responsibility of giving ad- vice should have had a great deal of experience in treat- ing insanity, and should exercise great caution before he advises that a person should be deprived of his liberty and placed under restraint. Before positively expressing the opinion that the patient is insane, and setting forth the facts upon which such an opinion is based, the physician should satisfy himself, beyond doubt, that the person alleged to be insane is really so. Not only one visit, but several visits may have to be made before all doubts as to the insanity of the patient are removed. In case the practitioner advises that the patient be treated at home, it should be distinctly understood that he is relieved of all responsibility for the restraint, that being assumed by the friends or the members of the family. The form of cer- tificate by which an insane person can be removed to an asylum is fixed by statute, and no other form is valid in America. In Pennsylvania the certificate must be signed by two respectable physicians, who have practised medi- cine for five years, both of whom must have examined the patient within one week of their signing the certificate, and who both must testify under oath that it is absolutely necessary for the safety of the individual and the public that the patient shall be placed under restraint in an asylum. The physicians signing the certificate should not be related by blood or marriage, or be officially connected in any way with the asylum in which the patient is to be confined. Practitioners cannot be too cautious in signing a certificate for the placing of a patient in an insane MEDICAL JURISPRUDENCE AND TOXICOLOGY. 1 7.'i asylum, false commitment rendering them liable to heavy punishment by an action at law. It should be remem- bered that, in many instances, physicians have been de- ceived by relatives interested in the management or dis- posal of an estate, and induced by their misrepresentations of the state of mind of the patient to sign a certificate con- signing him or her to an insane asylum. Judgment and caution must be exercised in signing the discharge of a patient from an asylum by the physician in charge, as well as in signing one of commitment. Patients are usually removed from an asylum by the members of their family or friends at the discretion and with the approval of the superintendent. In America there is no law preventing the liberation of the insane on recovery, except in cases of homicidal lunatics, who have been com- mitted to an asylum by an order of the court. The opinion of the practitioner is occasionally asked as to the capacity of an individual to make a will, to sign a contract, or to many. It should be remembered, strange as it may appear, that less mental capacity is required by law to make a will than to permit the managing of property or the enjoyment of personal liberty. The courts have ruled in many instances that patients, even when confined in iusane asylums, have made good wills, and have held as valid the most absurd wills, it having been shown that such wills were in perfect accordance with the life of the eccen- tric, but not therefore necessarily insane, testator. In order, however, that a will should be valid, the law requires that the testator should be sane, at least at the time of the making of the will. A will made when the testator was under the influence of liquor, or narcotized, or afflicted with the delirium of fever, would not be held 174 A MANUAL OF as valid. A person would not be disqualified, however, from making a will when poisoned by arsenic or strych- nia, provided his mind was clear, and the same may be said of a person suffering from typhoid fever, paralysis, or epilepsy. When a physician is consulted as to the capacity of a person to make a will, the examination of the testator should be made in private, or only in the presence of the nurse, or perhaps of one member of the family. The physician should satisfy himself that the testator is not under the influence of liquor, or of any drug; that he fully realizes the importance and the nature of the act he is about to perform ; that he is not affected by any delusions ; and that no undue influence has been brought to bear upon him. A most delicate question for the physician to answer, and his advice is often asked upon the subject, is that of the propriety of one person marrying another who has been insane, or in whose family insanity is hereditary. While, as a general rule, all marriages of such a character, as well as those in which there is a tendency in the con- tracting parties to inherit any disease, are to be discouraged, any advice to the contrary that may be given by the physician will not prevent their taking place, and nothing will be gained by his opposition. The family physician is often called upon to give advice as to the best means of bring- ing up children begotten by such unfortunate marriages. Hygienic treatment is all that can be recommended in such cases. It ought to be insisted upon, however, that the children should have pure country air, plenty of out-door exercise, plain but nutritious food ; that all ex- citement, especially at the age of puberty, should be avoided ; and, above all, that little or no mental effort MEDICAL JURISPRUDENCE AND TOXICOLOGY. 175 should be required, even though the child should thereby grow up comparatively uneducated. Criminal Responsibility of the Insane. — Of nil the ques- tions which the subject of legal medicine gives rise to, there is none more difficult or more worthy of consid- eration than that of the relations of insanity to criminal responsibility. In nearly every trial for homicide, how- ever brutal or revolting the crime, no matter how out- rageous or aggravated' the circumstances may be, after every other plea has been urged, the defence, as a last resource, attempts to prove that the murderer was insane. It might be supposed that the sophistry, flimsy rubbish, unworthy of being dignified by the name of argument, advanced by adroit counsel, could speedily be disposed of in all such cases by limiting the discussion to simply determining whether the defendant was afflicted with any mental disorder due to disease. The difficulty, however, which at once arises consists in deciding what shall constitute a test of the existence of a mental dis- order. At one time it was universally admitted that an individual was responsible unless totally deprived of his understanding and memory — not knowing what he was doing any more than an infant, brute, or wild beast. The knowledge of right and wrong was later considered as a test of responsibility in criminal cases. This test was afterwards so qualified that the knowledge of right and wrong was to have relation only to the particular act of which the individual was accused ; and it was still fur- ther modified in its being held that the person accused must have a knowledge of the consequences of the act. There can be no doubt, however, that insane persons have not only been fully conscious of the criminality of their acts, but have realized as well their conse- 176 A MANUAL OF quences and the punishment to which they rendered themselves liable. The knowledge of right and wrong, the consciousness of criminality, the realization of liability to punishment being possessed by insane persons, have in recent times led to the claim that only those individuals should be held irresponsible who have lost all power of control over their actions. The test of irresponsibility may be said to be, in this view then, the proof of a want of will-power — the power of choosing between good and evil being de- stroyed by disease. The accused would not, however, be held irresponsible if the crime was committed under the influence, temporarily, of liquor, or of a violent burst of passion, the latter condition being often attributed to im- pulsive or emotional insanity — a form of mental disorder for the existence of which there is no evidence. Not unfrequently, medical experts in insanity are also called upon by the courts to state whether a criminal under sentence of death is insane, in order to stay exe- cution. Medico-Legal Terms Defined. — In connection with cases of insanity certain legal terms are frequently made use of rather loosely, such as illusions, hallucinations, delusions, lucid intervals; but these terms should be defined, in order that the medical examiner may be qualified to answer intelligently in court questions involving their use. An illusion may be defined as a false impression due to a material basis, the impression being, however, distorted through some defect in the avenue of sense, or of the perceptive centre, as in the mistaking a tree for a man at night. Hallucinations differ from illusions in being perverted impressions, but without a material basis, at least immediately. A person afflicted with this MEDICAL JUEI8PEUDENCE AND TOXICOLOGY. 177 disorder imagines lie hears .strange voices, sees people where there are none, etc. Delusions may ho defined as beliefs in something purely imaginary, as when a pauper imagines he has become a millionaire, or when a million- aire believes he lias lost everything. Should a delusion be so strong as to affect the disposal of an estate by will, as when a parent has come to hate, for no reason, his chil- dren, whom he had formerly loved, the capacity to make a will should be disputed. If, however, the delusion with which an individual is affected is not connected in any way with the act about to be performed, the responsibility of such a person would not be questioned. By a lucid interval is meant a temporary intermission of insanity, during which period the individual recovers his reasoning powers. It may last for months, weeks, or only for a few minutes. It not unfrequently occurs in mania, and occa- sionally in dementia, but never in idiocy or imbecility. Duriug a lucid interval the law recognizes the power of a person to sign a contract, to make a will, to exercise civil rights, etc. Feigned Mental Diseases are usually considered by Writers upon medical jurisprudence separately from feigned bodily disorders. The expression mental dis- ease, whether feigned or not, regarded as something dis- tinct from bodily disease, is, however, an unphilosophical one, as there can be no disease, mental or otherwise, without some underlying change in organization. What- ever may be the psychological views held as to the nature of mind, whether it be regarded as an entity, a something independent — superadded to the body — an almost obsolete view now — or as a function of the nervous system, and, more especially in man, of the cerebral por- tion of it, a view accepted by all physiologists, is immate- 12 178 A MANUAL OF rial, at least as far as it affects the view universally accepted that a healthy mind is always found in a healthy body. In connection with the subject of insanity, and as a mere matter of convenience, the subject of feigned mental diseases may be as appropriately considered here as else- where. Mental diseases are most frequently feigned by criminals, in the hope of escaping imprisonment or capital punishment. It is frequently very difficult to prove in such cases that the criminal is malingering, in- sanity in one form or another being so well imitated. The criminal may keep up the deception for months, dur- ing which he may rave, beat the door, tear up his clothes and bedding, indulge in the foulest language and dirty habits, conduct himself in so outrageous a mauner as to necessitate the use of a strait-jacket — and even then not confessing the fraud. In the investigation of these cases it is most important to determine whether the individual has any motive in simulating insanity — such as that of escaping punishment for some crime. Another point to be determined is, whether the particular crime committed was incidental to a life of crime, perhaps the last act of a long series such as a hardened criminal, but not an insane person, might be expected to commit. Another point to be ascertained is, whether the culprit endeavored to escape, it being well known that insane persons exhibit a perfect indifference to the consequences of their acts. It should be also remembered that insane persons never admit that they are insane ; whereas, those simulating insanity are always anxious to impress every one with the fact that they are really insane. Of the different forms of insanity mania is that which is usually feigned by malingerers. As all maniacs are popularly supposed to be violent, the MEDICAL JURISPRUDENCE AND TOXICOLOGY. 17!) malingerer in attempting to simulate mania is particularly so, usually overacting the part; while the impostor, how- ever, usually sleeps soundly, the maniac is as violent by night as by day. Dementia is less rarely simulated than mania, as it is more difficult to imitate, while the fraud is more readily recognized, being at once disclosed by the slightest reasoning power manifested by the individual. 180 A MANUAL OP PART II. TOXICOLOGY. CHAPTER I. Frequency of Death from Poisoning — Definition of a Poison — Mode of Action of Poisons — Influence exerted on Action of Poisons by Habit, Sleep, Disease, etc. — Evidences of Poisoning derived from Symptoms, Post-mortem Appearances, Chemical Analysis, Experiments upon Animals, Circumstantial Evidence — Character of the Evidence the Chemical Expert may be Expected to give in Cases of Poisoning. In most cases of poisoning the duty of the physician making the post-mortem examination is usually limited simply to removing the stomach, intestines, etc., of the deceased person supposed to have been poisoned, and placing them in the hands of the chemist especially employed by the Commonwealth to make an exam- ination of their contents, with the view of deter- mining the cause of death. It is important, how- ever, that every physician should have some knowledge of toxicology ; that is, of the symptoms of poisoning, the nature of poisons, their antidotes, etc., as well as of the medical relations of the subject. The subject of toxi- cology, like that of insanity, is such an extensive one that its thorough consideration would demand a special treatise, far exceeding the scope of the present work. All that the author can hope to accomplish within his prescribed limits is to point out, in a very general way, what his own ex- perience suggests as to the kind of toxicological knowledge the medical expert, who is not an analytical chemist, should possess. MEDICAL JURISPRUDENCE AND TOXICOLOGY. 181 The readiness with which poisons may be obtained, the facility of administering them, the close resemblance which the symptoms and post-mortem appearances of poisoning frequently hear to those due to disease, account for the fact that so many homicides and suicides are committed by this means. Indeed, statistics show that, excepting the casual- ties due to war, poisoning is the most frequent of all the causes of violent death. Poison Defined. — A poison may be defined as a sub- stance which, introduced into the body in a state of health, by the mouth, rectum, skin, lungs, etc., ordinarily causes illness and often death, the injurious effects not being due, however, to purely mechanical action. According to the above definition, a substance would not be a poison which only affected a person when suffering from disease like that of gastritis, rendering him peculiarly susceptible, which is due to personal idiosyncrasy. Nor would frag- ments of glass, or iron, or other hard or sharp substances be classified as poisons, even though they should cause death when swallowed, the injurious effects experienced being due to mechanical action. It need not be added that the particular amount, large or small, of a substance necessary to cause death affords no basis for distinguishing certain substances as poisons from others which are not poisons. Half an ounce of oxalic acid may prove as fatal as half a grain of strychnia. The effects of poisons are both local and remote. In making an impression directly upon the part of the body with which the poison comes in contact, a poison acts locally ; in affecting some distant part of the body it acts remotely. Certain poisons act both locally and remotely — arsenic, for example, affecting the stomach locally, aud the brain remotely. In order that a poison should produce its effects, unless it be a cor- 182 A MANUAL OF rosive, it must be absorbed — pass into the blood. 1 That poisons are absorbed is proved by their being found in the blood, brain, and viscera. The rapidity with which this takes place will depend upon their solubility and the rela- tive fullness of the bloodvessels. Absorption will, there- fore, be favored by bleeding or purging through depletion of the vascular system. The effects of a poison injected directly into the blood are almost instantaneous. Mode of Action of Poisons. — A poison having once passed into the blood is carried by the latter throughout the system, being either eliminated with the bile, urine, saliva, pancreatic juice, and sweat, or deposited in the liver, spleen, kidneys, heart, lungs, brain, pancreas, mus- cles, or bones. Every organ would appear, therefore, to have a peculiar affinity for some one or more poisons, as shown either by the poison being excreted by a gland, as arsenic by the stomach, or by its being retained within an organ for a longer or shorter period, as lead by the brain and spinal cord. The time required for either the elimination or deposi- tion of a poison varies according to the particular poison taken and to the state of the system. Potassium iodide and turpentine may appear in the urine within a few min- utes after being swallowed. Arsenic may be found in the liver in four hours and earlier after it is taken, being usu- ally eliminated from the system within fifteen days if the individual should survive for that length of time. Anti- mony, on the other hand, may be found four months after having been taken, lead and copper over eight months. 2 The phenomena of nutrition would lead us to suppose 1 Christison : Treatise on Poisons, fourth edition, Edinburgh, 1885. 2 Orfila : Annales de Hygiene publique et de Medecine legale, second series, tome iii., Paris, p. 213. MEDICAL JURISPRUDENCE AND TOXICOLOGY. 1 83 that it is probably only that portion of the poison flowing in the capillaries to which its effects arc due. As this boars but a small proportion to that found in the stomach, which is often in large quantity, it is obvious that death cannot be attributed to the latter, which must be regarded as a surplus, a source of supply, should the poison circu- lating through the system be insufficient to produce its characteristic effects. The exact manner in which death is caused by poison must be admitted not to be as yet un- derstood, though the question has given rise to much dis- cussion. The view has been advanced that poisons act in so altering the composition of the blood as to render it unfit to maintain life. Even if this could be proved, it would not be an explanation of the modus operandi of poisoning. In the present state of toxicological knowledge, all that can be said is that opium, for example, causes narcotism by. acting upon the brain ; prussic acid, asthenia through its effect upon the heart ; strychnia, tetanus by its effect upon the spinal cord. As to why these particular sub- stances act in this peculiar way, no satisfactory answer can be given any more than as to why certain poisons are elim- inated with particular secretions, as mercury with the saliva. As a general rule, the larger the dose of the poison the quicker the action, the exceptions being afforded by sub- stances like arsenic, which, when taken in an overdose, induce vomiting, and are therefore rejected from the sys- tem. Certain poisons undoubtedly act antagonistically towards each other, the effect of the one poison being more or less neutralized by the other. Thus, for example, mor- phia antagonizes atropia, and atropia neutralizes strychnia. Indeed, so true is this in the case of the two latter alka- loids that in strychnia-poisoning atropia should be admin- istered as an antidote. On the same principle, digitalis 184 A MANUAL OF might be tried in cases of aconite-poisoning, there being an antagonism between these drugs also. The power of poisons to produce their characteristic effects is very much diminished by their prolonged use, enormous amounts of laudanum and morphia, for instance, being tolerated by confirmed opium-eaters, and arsenic by arsenic-eaters. Sleep, whether induced naturally or by opium, usually diminishes or retards the action of poisons, especially of the irritant kind. Certain animal substances, which, when introduced into the system, are very poisonous, often in- deed fatal, are, however, when swallowed so modified by the digestive fluids as to be rendered innocuous, as shown by the fact that persons are unaffected after sucking wounds made by poisoned arrows, snake-bites, etc. Disease modifies the action of poisons. Persons suffering with apoplexy and inflammation of the brain are very susceptible, for example, to the action of opium. On the other hand, large quantities of opium are tolerated in tetanus and mania-a-potu. The evidences in cases of al- leged poisoning are afforded by the symptoms, the post- mortem appearances, chemical analysis, experiments upon animals, circumstantial evidence. Evidence of Poisoning derived from Symptoms. — In con- sidering the symptoms presented by a person supposed to have been poisoned, it is most important to ascertain whether, at the time of the attack, the person was perfectly well, whether the symptoms appeared shortly after the taking of food or drink, and whether any other persons were affected in a similar manner. The great difficulty experienced by the medical examiner in determining, from the symptoms alone, whether a person has been poisoned, arises from the similarity between the symptoms of disease and those MEDICAL JURISPRUDENCE AND TOXICOLOGY. 185 due to poison. Tims, for example, the symptoms of ma- lignant cholera, cholera morbus, peritonitis, ulcer of the stomach resemble very closely those due to irritant poi- sons. Indeed, eases of arsenic-poisoning have been mis- taken for attacks of cholera morbus. On the other band, the effects of narcotic poisons resemble in many respects those due to apoplexy, inflammation of the brain, certain cardiac disorders, etc. The above examples among many which might be given serve to prove that the symptoms alone in any case would not warrant the medical examiner in stating positively that a person had been poisoned, nor, on the other hand, in warranting him to attribute to dis- ease an alleged case of poisoning. In addition to what has already been said as to the manner of making post-mortem examinations, it is espe- cially important, in connection with poison cases, that the stomach and other viscera should be placed in a perfectly clean glass jar. Otherwise the defence on trial might plausibly argue that the poison found by the chemist was derived from the dirt in the jar, and not from the viscera of the person alleged to have been poisoned. Further, in case the stomach or other viscera are to be submitted to a chemist for analysis of their contents, the physician who makes the post-mortem examination should pack the jar with its contents securely in a box, seal the latter up, and label it. It is desirable, where possible, for the medical examiner to place the box in the hands of the chemist himself. Whoever delivers it, however, should take a receipt for it. The neglect of such precautions on the part of the physician making the autopsy in a poison case may give rise, on trial, to the objection that the stomach, etc., in passing through different hands, may have been tampered with, and the testimony of the chemist who 186 A MANUAL OP fouud the poison may be thereby materially weakened. In opening the stomach in poison cases it will be found most convenient to make the incision along the lesser curv- ature; then, after collecting and measuring the contents, to spread the stomach out upon a clean glass plate, the inner or mucous surface being uppermost; the latter should then be examined most carefully both for lesions and the remains of the poison. Post-mortem Appearances. — Among the post-mortem signs usually presented in poison cases may be men- tioned redness, softening of the mucous membrane of the stomach and intestines, ulceration and perforation. It need scarcely be mentioned, however, that, as the same signs may be due to disease, the medical exam- iner should be cautious in attributing them, even in suspicious cases, to poison. Not unfrequently remains of poison, such as crystals of arsenic, pieces of phosphorus, vegetable leaves, etc., may be found in the stomach and intestines. In cases of poisoning by prussic acid, opium, nicotine, etc., the odor of these substances on opening the body becomes very perceptible. Occasionally the cheeks, mouth, tongue, and dress of the deceased may be stained, as in cases of poisoning by mineral acids. One of the most convincing of the evidences of poisoning that can be adduced is the discovery of the poison. 1 In order to prove that death was caused by poisoning, the law, how- ever, does not require that the poison should be actually discovered, many criminals having been convicted on other evidence, circumstantial and otherwise. Indeed, if the discovery of the poison was essential to conviction, many criminals would escape, as there is no reliable, certain test 1 " Tunc demum res certa, erit, ubi venemum ipsum reperietur facile agnoscendum " (Wharton and Stille : op. cit., vol. ii. p. 44). MEDICAL JURISPRUDENCE and TOXICOLOGY. 187 for many poisons, especially of the animal and vegetable kinds. On the other hand, the mere finding of a poison within the stomach would not necessarily lead to convic- tion if the lesions usually produced by the poison were not present; and if other proof, such as symptoms, circum- stantial evidence, etc., were absent. Indeed, it might be argued, in such a case, that the poison had been introduced into the stomach after death for some malicious purpose, with the motive perhaps of exciting suspicion and of leading to the conviction of some innocent person. The fact that the poison was found in the liver, spleen, etc. would be a much stronger proof that death was caused by the poison than the finding of it in the stomach alone, as in the former case it would be inferred that the poison had been absorbed. It must be remembered, however, that a poison might be introduced into the stomach or rectum after death, and thence by osmosis pass possibly all through the body, for, although the bony cranium and spinal column would prevent osmosis, nevertheless, if the poison were im- bibed by the nerves, it might possibly be transmitted by the latter not only to the cord, but even to the brain itself. Chemical Analysis. — In making an analysis it is import- ant that the chemist should inform himself as to the nature of the symptoms, as well as of the post-mortem appearances presented, inasmuch as these may serve, to some extent at least, to indicate the nature of the poison taken. In every case the analysis should be made as carefully and as thor- oughly as possible. As a matter of precaution only one portion of the suspected substance should be analyzed at a time, the remaining portion being reserved in case an acci- dent should happen, or there should arise a necessity for future investigation. The substance suspected to be poison ought to respond to all the tests. It is also most import- 188 A MANUAL OP ant that the reagents, previous to being used, should have been determined to be pure, so-called " chemically pure " reagents often containing impurities. In many analyses it is of advantage to reduce the bulk of the liquid by evaporation, since the quantity of poison present might be so small as not to respond to the ordinary tests. Not- withstanding, however carefully the analysis may have been made, the chemist fails in many instances to discover any poison. It must be remembered, in connection with failures to find poison in those cases where all the other evidence concurs in showing that poison had been taken, that the latter may have been vomited or have passed out of the system in the feces and urine. The poison, fur- ther, may have been of such a nature as to be unrecogniz- able by any means at present known, or to have been de- composed in the blood or tissues during life or after death. Experiments on Animals. — In those cases where the poison cannot be determined by either the symptoms, post-mortem appearances, or chemical analysis, there remains still another resource — that of experimentation upon animals. For ex- ample, in an obscure case of strychnia-poisoning, some of the suspected matter, found perhaps in the stomach of the deceased, might be injected subcutaneously into a frog, the latter animal, as is well known, being extremely suscep- tible to the effects of that alkaloid. 1 Criminals have been convicted of giving digitalis and aconite in this way, these poisons having been recognized through their char- acteristic effects produced upon animals. It is an interest- ing fact, in this connection, that animals enjoy an immunity from being poisoned by certain plants which, when eaten by man, usually prove fatal ; and, further, that man may 1 Orfila : Traite des Poisons, troisieme edition, tome premier, Paris, 1826, p. 31. MEDICAL JURISPRUDENCE AND TOXICOLOGY. 189 be poisoned by outing an animal that has previously fed upon such plants. Thus, it is well known that the milk of cattle browsing upon the herbage in certain parts of South America, and the meat of the rabbit which has eaten bel- ladonna, will prove poisonous to human beings partaking of them. 1 Circumstantial Evidence. — Although the consideration of the circumstantial evidences of poisoning in a crim- inal case does not constitute a part of the duty of the medical examiner, nevertheless a knowledge of all the circumstances bearing upon the case will be of advan- tage. Among such circumstances may be mentioned par- ticularly : Whether the person accused had any motive for poisoning the deceased. Was there any evidence that the accused had recently purchased the particular poisou found, or that he had had any in his possession for some time? Did he give the deceased always his meals? Was medical advice sought, and, if so, was the medicine always given by the accused ? If any matters were vomited during the illness of the deceased, were they submitted to the physician for examination, or thrown away at once and nothing whatever said about them? Was the burial premature and very quiet ? Was an autopsy objected to? It is needless to say that, if the accused acted in such a way, there would be good reason, indeed, to suspect foul play. Character of Evidence of the Chemical Expert. — In all criminal cases of poisoning the physician or the chemist, or whoever makes the analysis, must be prepared to answer at the trial such questions as the following : Could the sickness or death be ascribed to poison, and, if so, to what particular poisou ? Would such a poison as 1 Guy and Ferrier : op. cit., p. 372 ; Beck : op. cit., vol. ii. p. 414. 190 A MANUAL OF that alleged to have been given produce death if adminis- tered in sufficient quantity ? At what period was the poison given? Could such a poison disappear so entirely from the system as to leave no trace ? Might the poison discovered in the body of the deceased have been derived from some other source than that which was claimed to show that it had been criminally administered? 1 The an- swers to be given by the medical witness to such questions will largely depend upon what particular kind of poison may have been given, as will become more apparent when the different kinds of poisons will have been considered. The effects of poison are simulated occasionally; the imposture will be discovered, however, in time at least, if not by other means. Insane people are frequently deluded with the idea that attempts are being made to poison them, or that they have been poisoned. 1 Tardieu, A.: Etude medico-legale et clinique sur I' Empoisonnement, Paris, 1867. MEDICAL JURISPRUDENCE AND TOXICOLOGY. 1 !) I CHAPTER II. Classification of Poisons — Irritant Poisons — Poisoning by Mineral Acids, by Alkalies and their Salts, Noxious Gases — Poisoning by Phosphorus, Arsenic, Antimony, Mercury, Lead, popper, etc — Poi- soning by Oxalic Acid, Carbolic Acid, etc. — Poisoning by Decom- posed Food, Ptomaines, Neurotic Poisons — Poisoning by Opium, Alcohol, Ether, Chloroform, Chloral, Nux Vomica, Strychnia, Bel- ladonna, Stramonium, Tobacco, Lobelia, Hydrocyanic Acid. Systematic writers upon the subject of Toxicology vary very much in the manner in which they classify poisons. In this manual, however, poisons will be regarded as con- sisting of only two kinds : Irritants and Neurotics. 1 Poisons Irritants f Mineral Acids, Alkalies, Phosphorus, Bro- mine, Iodine, Arsenic, Antimony, Mer- cury, Lead, Copper, Tin, Bismuth, Car- bolic Acid, Trichiniasis, Ptomaines. Opium, Alcohol, Anaesthetics, Chloral Hydrate, Carbon Ox- ide, Carbon Dioxide. r Cerebral Spinal . Neurotics Cerebro- spin , -J Depressants -J . Strychnos Nux Vomica. {Stramonium, Hy- oscyamus, Atro- pa Belladonna. ( Nicotiana Taba- cum, Lobelia, Aconitum. Digitalis, Cocculus Indicus, Acidum Hyd rocy an i cu m . Irritant poisons include substances which, when swal- lowed, give rise to an acrid, burning taste, followed by nausea, vomiting, cramps in stomach, purging, the matters 1 Taylor : op. cit., p. 78. [Asthenics 192 A MANUAL OF vomited and purged being often mixed with blood, these symptoms being due to inflammation of the mucous mem- brane of the alimentary canal, terminating not unfrequently in ulcer, perforation, and gangrene. They may possess simple irritant properties or specific ones, and are derived from the mineral, vegetable, and animal kingdoms. The simple irritant poisons include such substances as the min- eral acids and alkalies. Among those possessing specific properties may be mentioned phosphorus, arsenic, anti- mony, mercury, oxalic and carbolic acids, cantharides, poisoned meat, fish, etc. Neurotic poisons include such substances as have a spe- cific action upon the brain and spinal cord, causing head- ache, giddiness, drowsiness, stupor, delirium, coma, con- vulsions, paralysis. They are derived from the vegetable kingdom and include substances like opium, chloral, strychnia, atropia, Calabar bean, prussic acid, etc. Irritant Poisons. — Poisoning by Mineral Acids. — As a general rule, most cases of poisoning due to mineral acids are accidental in character, suicide being only occasionally committed by such means, and homicides but rarely. As the symptoms, post-mortem appearances, general treat- ment, in poisoning by the different mineral acids, are very much the same, they may be conveniently considered to- gether. The symptoms in cases of poisoning of this kind, which depend more on the degree of concentration than on mere quantity, are a burning sensation in the mouth, fol- lowed by violent pain in the stomach, vomiting of dark- colored coifee-grounds-like matters containing blood, and occasionally portions of mucous membrane. In all cases of poisoning by mineral acids, magnesia, chalk, plaster oif the walls (if nothing better), soap-suds, oil, milk, mucilagi- nous drinks, flaxseed tea, or barley-water may be adminis- MEDICAL JURISPRUDENCE AND TOXICOLOGY! L93 tered. If undiluted acid has been swallowed, however, there is but little hope that the remedies jnsi mentioned or any others will do much good. The smallest recorded quantity of sulphuric acid known to have destroyed life was one drachm, the shortest known period at which death has taken place being within two hours. 1 On post-mortem examination stains and corrosions are found on all parts with which the acid has come in con- tact. The stomach is filled with black, yellow, or brown fluid, perhaps distended with gas, its mucous membrane charred or inflamed, perforation not being uncommon in cases of sulphuric acid poisoning. The skin is stained black or dark brown by sulphuric acid, yellow by nitric acid, white by hydrochloric acid. In cases of sulphuric acid poisoning the contents of the stomach should be fil- tered and then treated with any soluble salt of barium. The dense white precipitate produced, insoluble in acid and alkalies, with charcoal and blowpipe will yield barium sulphide, which in turn with a mineral acid gives sul- phuretted hydrogen, recognizable by the black stain it gives to filtering paper dipped into a solution of lead salt. The smallest quantity of nitric acid recorded as having destroyed life was two drachms, death having taken place within two hours. 2 In cases of poisoning by nitric acid, the matters ob- tained from the stomach should be first filtered. The clear acid liquid so obtained should then be heated and a weak solution of potassium carbonate added. Paper dipped into a concentrated solution of the latter will afterwards burn with deflagration. A few drops of the filtered solu- tion evaporated to dryness on a glass slide will give 1 Christison : op. cit., p. 162. 2 Wharton and Stille : op. cit., vol. ii. p. 179. 13 194 A MANUAL OF crystals of potassium nitrate. On making a solution of these crystals and adding a crystal of ferrous sulphate with a drop or two of strong sulphuric acid, the green color of the crystal will change to reddish-brown, due to the formation of ferric sulphate. Morphina and brucina will serve as tests for concentrated nitric acid, being turned red by the acid. Ruddy brown fumes are also given off when nitric acid is poured on copper. In order to extract hydrochloric acid from the stomach it is only necessary to add silver nitrate to the filtered contents, the white pre- cipitate silver chloride formed being readily recognizable by being soluble in liquor ammonia? and precipitable by nitric acid, blackening upon exposure to light and melting into a mass known as horn silver when heated. The fact that hydrochloric acid dissolves gold leaf in the presence of nitric acid affords a convenient test for the concentrated acid, as also the white fumes given off with vapor of am- monia. The smallest quantity of hydrochloric acid known to have destroyed life is half an ounce, the shortest period within which death took place being two hours. 1 Poisoning by Alkalies. — The alkalies, potassa, soda, and ammonia, are rarely used for homicidal purposes. As potassa and soda are, however, extensively used in the arts, in the manufacture of glass and soap, under the name of pot- and pearl-ashes, soda ashes and soap lees, and ammonia in the form of aqua ammonia? for various household purposes, illnesses and occasionally death have occurred as the result of taking them accidentally. The symptoms of poisoning by the alkalies are an acrid, nauseating taste, followed by a burning heat in the throat and stomach, violent abdominal pains, vomiting and purg- ing. Ammonia, being more irritating than potassa or soda, affects the respiratory organs especially, inducing a chok- 1 Taylor : op. cit., p. 102. MEDICAL JURISPRUDENCE AND TOXICOLOGY. 195 ing sensation. In cases of poisoning by any of the alka- lies, vinegar and water, lime or orange juice, oil, which forms -with alkali soap, should be given, opium being administered to relieve pain. The quantity of potassa or soda or ammonia that may prove fatal is variable, death having been caused by half an ounce of caustic potassa and by forty grains in solution and by two drachms of ammonia. 1 Persons have, however, recovered after swal- lowing over an ounce of ammonia. Death may take place from poisoning by alkalies within a few hours or days, or may be protracted several months. In fatal cases, on post-mortem examination, the mucous membrane of the mouth, throat, and gullet will be found corroded, often blackened, and even completely destroyed, the larynx and bronchi being particularly inflamed and softened in cases of ammonia-poisoning. In examining the contents of the stomach, as a general rule, the organic matters can be removed by evaporation and subsequent heating ; the ash remaining being digested with distilled water and filtered, the potassa or soda will be found in solution as a carbonate. Potassium compounds give a violet color, sodium compounds a yellow color to the smokeless flame of spirit or gas. The presence of these alkalies can be readily recognized also by means of the spectroscope. Potassium can also be tested for by using tetrachloride of platinum, which throws down a yellow granular precipitate consisting of potassio-platino chloride. In making use of this test, the absence of ammonia must be insured. Soda may be recognized from the white pre- cipitate thrown down by the addition of potassium anti- moniate. Ammonia may be extracted from the stomach by distilling about one-fourth of the liquid, the vapor being carried through a bent tube into a well-cooled re- 1 Woodman and Tidy : op. tit., pp. 92, 105. 196 A MANUAL OF ceiver containing a small quantity of water acidulated with hydrochloric acid. If no ammonia should be given off, the contents of the retort should be treated with alcohol filtered and redistilled with lime hydrate, by which free ammonia, perceptible from its odor, will be obtained. As ammonia is one of the products of putrefaction, if the con- tents of the stomach should be found in that condition it will be useless to attempt to make an analysis. A con- venient test for ammonia is -platinum tetrachloride, which gives a yellow precipitate. The alkaline salts and earth, potassium nitrate or salt- petre, used in medicine and in the manufacture of gun- powder, potassium bitartrate or cream of tartar, potassium sulphate, chlorinated soda and potash or bleaching salts, magnesium sulphate or Epsom salts, the salts of barium, strontium, calcium, and even common salt, have all proved fatal when taken in overdoses or in large quantities. As cases of poisoning from such substances were not homi- cidal in character, but resulted from accident, it will not be necessary to describe the symptoms, post-mortem ap- pearances, etc. It may be mentioned, however, that the proper treatment in such cases, generally speaking, is to evacuate the poison by emetics and mucilaginous drinks, and the administration of antiphlogistic remedies. Poisoning by Noxious Gases. — Among the irritant poisons may also be included nitrous acid, sulphurous acid, hydrochloric acid, and chlorine gases. The dele- terious effects of the fumes of such gases are well known, causing irritation and inflammation of the throat, eyes, and air-passages, inducing in some cases even spasm of the glottis. The production of these gases is incidental to various manufacturing processes, nitrous acid gas being generated upon a large scale in water-gilding and brass- MEDICAL JURISPRUDENCE AM) TOXICOLOGY. 107 button-making, sulphurous add gas in bakers' ovens, hydrochloric acid gas in potteries. As such cases of poi- soning arc often of a chronic rather than acute character, and but rarely become the subjed of medico-legal investi- gation, it will not be necessary to dwell further upon the noxious effects of these gases. Poisoning by Phosphorus. — With the description of phos- phorus poisoning wc begin the consideration of that class of irritant poisons which not only act upon the mucous mem- brane of the alimentary canal, or the part of the body they come directly in contact with, but also upon remote parts of the system — the nervous centres being often especially affected. It is true that some of the alkaline and earthy salts just mentioned possess similar properties to some extent ; but, as poisoning is rarely caused in this way, their specific properties were not referred to. Phosphorus is but seldom used for homicidal and not very frequently for suicidal purposes. Most cases of poisoning of this kind are acci- dental in character, caused by swallowing the phosphorus paste used for destroying vermin, or the tops of lucifer matches. Poisoning by phosphorus is much less common than formerly, the red or amorphous form, which is not poisonous, being so much more used than the yellow variety. In acute cases the symptoms vary at the com- mencement, sometimes setting in rapidly, at others being protracted. As a general rule, within from one to two hours, a peculiar, disagreeable taste is experienced, accom- panied with intense warmth in the stomach and bowels, which gradually turns into a violent, burning pain. Eruc- tations having a garlicky odor, followed by nausea, vomit- ing and purging are not infrequent. The matters vomited are usually dark-colored, and have the garlicky odor of phosphorus. The pupils are dilated, the abdomen dis- 198 A MANUAL OF tended, the extremities cold, the pulse weak, the thirst intense. Between the third and fifth day, if the case is a protracted one, jaundice appears, often accompanied with retention of urine and delirium, the patient dying possibly in convulsions or comatose. Recovery is very rare. The most constant symptoms in chronic phosphorus poisoning are weakness and fatigue, pains in the abdomen, with diarrhoea, intermittent toothache, carious teeth, with gums swollen and distended with pus ; the complexion sallow, eruption upon the skin ; falling off of the hair, increase of phosphates in the urine. There is no chemical antidote for phosphorus. The poison should be removed as soon as possible. If the patient is seen shortly after taking the poison, the stomach- pump should be used ; otherwise, an emetic of sulphate of zinc or sulphate of copper should be administered, the latter being given in three-grain doses, well diluted, at in- tervals. Magnesia or chalk, in gruel, should be given. If the poison has had time to reach the intestines, purging should be tried ; on no account should oil be given, as the phosphorus would be dissolved, and its absorption greatly promoted. It is most important, as a precautionary measure, that those engaged in phosphorus manufactories should be extremely cleanly in their habits, changiug their clothes after work, washing their faces and hands, and rinsing their mouths with some slightly alkaline wash. Saucers filled with turpentine should be placed about the factory, the fumes appearing to exert a protective effect. The smallest quantity of phosphorus known to have de- stroyed life was one-and-a-half grains in a man, one-eighth of a grain in a woman. The one-fiftieth of a grain has, how- ever, killed a child. 1 Death in cases of acute phosphorus- poisoning usually takes place within a period of from three 1 Woodman and Tidy : op. cit., p. 71. MEDICAL JURISPRUDENCE AND TOXICOLOGY. 199 to six days. In one case recorded death occurred in half an hour. Chronic cases may, however, last for mouths or even for years. On post-mortem examination the mucous membrane of the alimentary canal is usually found inflamed, softened, and discolored. In chronic cases the most important change observed is the fatty condition of the liver, kid- neys, heart, muscles, etc., the fat being probably derived from the albumen of the tissues. The best way of extract- ing phosphorus from the stomach is that of Mitscherlich. This method consists in distilling the suspected fluid in the dark with a small quantity of dilute sulphuric acid, the object of the latter being to neutralize the ammonia developed during putrefaction. The vapors are made to pass through a tube kept cool by running water into a receiver, a flash of light appearing every time that the phosphorus vapor condenses in the tube. This method is so delicate that one part of phosphorus may be detected by it in one hundred thousand of substance. Bromine and iodine, like phosphorus, are irritant poisons, possessing specific properties as well. Bromine has been used to commit suicide, and iodine in over-doses has caused death accidentally. The symptoms of poisoning by bromine are spasmodic action of the muscles of the larynx and phar- ynx, with great difficulty in breathing, followed by burn- ing pain in the stomach. An ounce of bromine has caused death in seven hours and a half. Iodine in large doses causes a burning heat in the throat, pain in the abdomen, vomiting, purging. In such cases emetics should be ad- ministered. The post-mortem appearances presented are those of an irritant poison. Fatal results have followed from the taking of twenty grains of iodine. Death occurs usually within thirty hours after the taking of the poison. 200 A MANUAL OF It may be mentioned that caution should be exercised by the physician in prescribing iodide of potassium, as some persons are very susceptible to its influence. In such cases, headache, abdominal pain, thirst, inflammation of the nos- trils and eyes, salivation, pustular eruption follow its ad- ministration even when given in small doses. Poisoning by Arsenic. — Arsenic is found in nature in the metallic form, or in combination with other metals, such as zinc, copper, iron, and with sulphur in the form of orpi- ment and realgar. Arsenic is extensively used in the arts, in the manufacture of enamel, glass, composition candles, vermin-killers, fly-powders ; ship-builders protect their tim- ber from worms, farmers preserve their grain, grooms im- prove the coats of horses, and women their skin, by arsenic. 1 Arsenic is so readily obtained and so easily administered, and is so easily suspended in tea, coffee, milk, and soup, etc., that it is of all poisons the most frequently used for homicidal and suicidal purposes. Of the various prepara- tions of arsenic, the important ones, medico-legally, are the white oxide commonly known as arsenious acid, the yellow sulphide or orpiment, the green arsenite of copper or Scheele's green, the liquor potassse arsenitis or Fowler's solution. In whatever form taken, though, whether solid, liquid, or gaseous, or howsoever applied, either as a wash, an ointment, or a plaster, arsenic acts as a poison. Arsenious oxide, or white arsenic, the form of arsenic most commonly, made use of for poisoning purposes, oc- curs in commerce as a heavy white, opaque, or translucent powder, or in masses. It is nearly tasteless, and but slightly soluble in cold water, only one-half of a grain being dissolved by an ounce of water; the solubility is increased by hot water, alkali, but diminished by 1 Guy and Ferrier : op. cit., p. 436 ; Tardieu : op. cit., p. 323. MED1CAJ; .IIJKIsritUhKNCK AND TOXICOLOGY. 2<>| organic matter. As a general rule, the symptoms of arsenical poisoning develop gradually, being usually de- layed for from half an hour to an hour, or even Longer. In certain cases, especially when a large dose has been taken, poisonous symptoms may appear almost immedi- ately. The countenance expresses depression and great suf- fering. A burning pain is experienced in the pit of the stomach, which is increased by pressure; vomiting is in- variably present, the matters vomited consisting of a white gum-like substance or of a brown liquid mixed with bile or blood. Diarrhoea is usually present, accompanied with pains at the anus ; severe cramps are felt in the legs. The throat is hot and constricted, the tongue furred, and thirst is intense. The skin is hot and dry, the head aches, the pulse is rapid and small. The conjunctivas are reddened, the eyes smart, and are suffused, and light is dreaded. Though there are usuallv extreme restlessuess and nervous twitchings, the mind, as a general rule, is clear. Death may occur with convulsions of an epileptiform character, or may resemble, as already mentioned, that of cholera morbus. In some cases death takes place very quickly, as if due to shock. The symptoms in chronic cases of arsenic poisoning, as, for example, where workmen have been ex- posed to the vapors of arsenic, are much less pronounced than in acute ones. The eyes are inflamed and watery ; headache, giddiness, vomiting, diarrhoea may be present ; the skin is affected with an eczema ; there may be some local paralysis ; salivation and even mania have been noticed. In cases of arsenical poisoning, if the patient is seen soon after taking the poison, the stomach-pump should be used. If any length of time has elapsed, however, hot milk and water and emetics of sulphate of zinc and mus- 202 A MANUAL OP tard should be given. If there has been much vomiting, eggs and milk and magnesia, with sugar in milk, should be administered, the latter forming an insoluble compound with arsenious oxide. Stimulants should be given in a state of collapse, and anodynes for nervousness. The anti- dote in most repute in cases of arsenical poisoning is the hydrated sesquioxide of iron, by which the arsenic is con- verted into the insoluble arseniate of iron. It can be freshly and quickly prepared by diluting the tincture of the chloride of iron, adding ammonia in excess, collecting the precipitate on filtering paper, and carefully washing and administering at once when moist, The hydrated sesqui- oxide of iron so prepared should be given in large doses and frequently, followed later by a dose of castor oil. Freshly-precipitated hydrated peroxide of magnesium has also been proved serviceable as an antidote. Nitrate of potassium may be given also in repeated doses in order to promote the elimination of the poison by the kidneys. It appears that, however large the amount of arsenic taken, no more than two grains need be absorbed to cause death. At all events, that amount has proved fatal, though there have been recoveries after much larger doses. Death usually takes place within twenty-four hours, though it may occur within twenty minutes or be delayed ten to sixteen days after taking the poison. On post-mortem examination, the mucous membrane of the stomach will be usually found highly inflamed, present- ing, in some cases, a uniform deep red color; in others only red patches. In some cases the mucous membrane is thickened, in others softened and easily separated. Ulcera- tion of the stomach but rarely takes place. However intro- duced, arsenic appears to have some specific effect upon the stomach. Not unfrequently the small intestine, the cse- MEDICAL JURISPRUDENCE AND TOXICOLOGY. 203 cum, and the rectum arc inflamed as well as the stomach. It must be mentioned; however, that in some cases of arsenic poisoning there is an entire absence of any signs oi inflammation, even though there had been symptoms of inflammation during life. Arsenic is not a cumulative poison, being only tempo- rarily deposited in the liver and other organs, and rapidly eliminated in the urine and other secretions; accordingly, no trace of it is likely to be found after death, should the person have survived two or three weeks after taking the poison. On the other hand, arsenic, as is well known, being a powerful antiseptic, the bodies of persons poisoned by this means may be so well preserved as to admit of the detection of the poison months aud even years after burial. Under such circumstances the absence of cadaveric odor is noticeable, and there will be frequently observed numerous yellow patches on the abdominal viscera, due to the forma- tion of yellow sulphide of arsenic through the action of sulphuretted hydrogen upon arsenious oxide. In examin- ing the contents of the stomach, the examiner should first carefully look for solid particles of arsenious oxide in the walls of the stomach itself, as well as among its contents. The stomach should then be cut up into small pieces with a perfectly clean pair of scissors, and, together with its contents, placed in a clean porcelain evaporating dish. Distilled water, with one-sixth its bulk of pure hydro- chloric acid, should be added, and the whole gently boiled for about an hour, by which time most of the solid por- tions of the mixture will be disintegrated. After cooling, the mixture should be filtered, the filtrate being after- wards concentrated over a water-bath. In order to ex- tract arsenic from the liver, spleen, or other organs, the tissues should be very finely cut up, and, after being 204 A MANUAL OF treated with distilled water and hydrochloric acid, must then be filtered. The different tests for arsenious oxide may be regarded as being of three kinds — solid, liquid, and what may be called special tests. Of the solid tests the three following will be found convenient and easy of application : The first test consists in heating upon charcoal the suspected substance ; if the latter be arsenious oxide, the odor of garlic will become very perceptible. The second test is to slowly heat the substance in a narrow glass tube until it sublimes; if arsenious oxide be present, there will be formed on the cool part of the tube a white ring of octahedral crys- tals (Fig. 41), which can be seen by a good magnifier. It is true that calomel and corrosive sublimate will produce white rings under the same circumstances, but they will not con- sist of octahedral crystals. The third test is to heat the sus- pected substance in a reduction-tube (Fig. 42) about three inches long and an eighth of an inch in diameter with dry sodium carbonate and charcoal, the flux being in the pro- portion of about four to one of the substance examined and intimately mixed with it. If arsenious oxide be pres- ent, it will be reduced, metallic arsenic being condensed as a brilliant steel-gray ring upon the upper part of the tube. That the ring so formed does consist of arsenic is still further shown by the fact that it is entirely soluble in sodium hypochlorite. The liquid tests are the ammonio-sulphate of copper, the ammonio-nitrate of silver and sulphuretted hydrogen. Ammonio-sulphate of copper, when added to a solution of arsenious oxide, throws down a light green arsenite of cop- per, the precipitate being soluble in ammonia and free acids. The characteristic color does not appear immedi- ately if the arsenic is in very small quantities. The am- MEDICAL JURISPRUDENCE AND TOXICOLOGY. 205 monio-sulphate of copper, when used for this purpose, should be freshly prepared by adding to a somewhat dilute Fig. 41. Crystals of arsenious acid by sublimation, magnified 30 diam- eters. Fig. 43. Deposit obtained by Marsh's apparatus : a, metal ; b, mixed deposit ; c, arsenious acid. Fio. 42. Ordinary reduction- tube, with two subli- mates ; the upper, brownish-black ; the lower, the pure metal in an annular deposit. solution of sulphate of copper just enough liquor ammo- nia? to throw down a pale blue precipitate. Ammonio- nitrate of silver gives to a solution of arsenious oxide a canary yellow precipitate of arsenite of silver soluble in an excess of ammonia. The reagent can be freshly pre- pared by adding just enough liquor ammonia? to a solution of nitrate of silver to precipitate the brown oxide of sil- 206 A MANUAL OP ver. It should be mentioned, however, that as various organic matters which might be present in the contents of the stomach will produce similar colors with both copper and silver, the precipitates of arsenite of copper and silver obtained by the liquid tests should be submitted to further tests, such as that by the reduction method just described. The sulphuretted hydrogen test consists in passing washed sulphuretted hydrogen gas through the solution of the suspected substance slightly acidified with hydrochloric acid. If arsenious oxide be present, there will be precipi- tated the yellow tersulphide of arsenic, soluble in alkalies but insoluble in acids. In dilute solutions the excess of gas may have to be driven off before the precipitate is sep- arated. The sulphide of arsenic so obtained should still further be tested by subliming it with a reducing agent. It should be mentioned, in connection with this test, that somewhat similar precipitates are yielded by cadmium, tin, and selenium in the presence of sulphuretted hydrogen. For all practical purposes the cadmium sulphide need only be considered in this respect, and it should not even prove a source of fallacy ; it is distinguished from arsenic sul- phide in being soluble in acids and insoluble in alkalies, and further in forming a brown oxide instead of a ring when dried and oxidized on charcoal. The special tests for the detection of arsenious oxide are known as Marsh's and Reinsch's tests. The principle of Marsh's test is based upon the fact that arsenious oxide is decomposed in the presence of nascent hydrogen, arseni- urettcd hydrogen gas being formed from which the arsenic can be obtained as a brilliant steel or brown-gray deposit in the form of rings. The simplest method of performing Marsh's test is first to generate perfectly pure hydrogen gas and then to add to the materials generating the latter MEDICAL JUKISPKUDENCE AND TOXICOLOGY. 207 the solution suspected to contain arsenious oxide. The hydrogen gas may be generated by putting strips of chem- ically pure zinc and diluted sulphuric- acid into a suitable glass vessel provided with two mouths. Through one of the mouths a glass tube should pass down vertically below the surface of the liquid, and through the other mouth a tube bent at right angles by means of which the hydrogen gas generated may issue. The gas should be dried by al- lowing it to pass through a tube containing pieces of fused calcium chloride or pumice-stone moistened with sulphuric acid, then through a horizontal tube of hard German glass about a foot long, turned up at the farthest end and ter- minating in a small point, so that the gas as it escapes will burn in a jet. It is most essential, before lighting the jet of gas, that all atmospheric air be excluded from the tubes, otherwise a violent explosion will ensue. After waiting a sufficient length of time the gas may be lighted, and it will burn with a faintly luminous, scarcely perceptible flame. The purity of the materials used in generating the hydro- gen gas must now be demonstrated. This is accomplished by applying the flame of a large spirit-lamp to the hori- zontal glass tube until it becomes red hot. Should no stain or deposit occur just beyond the heated spot, or no deposit form ou a piece of white porcelain held over the burning jet, the absence of arsenic is assured (Fig. 43). A small quantity of the suspected solution being now introduced through the vertical tube, any arsenious oxide present will be decomposed, arseniuretted hydrogen will be set free, and will burn with a pale blue flame, white fumes being fre- quently evolved having an alliaceous odor. If the latter be made to pass into a short wide glass tube, they will con- dense as a white powder, sometimes crystalline in form, recognizable as arsenious oxide. If a white porcelain 208 , A MANUAL OF plate be now placed over the flame of the arseniuretted hydrogen, a deposit is formed consisting of three concen- tric rings, the inner ring being metallic arsenic, the middle ring arsenic and arsenious oxide, the outer ring arsenious oxide. It should be mentioned, in connection with Marsh's test, that antimony in the presence of hydrogen will yield a deposit very similar to that due to arsenic. The arsenical deposit can, however, be distinguished from the antimo- nial one, as the former is soluble in a solution of chlori- nated lime, but insoluble in hydrochloric acid, whereas the latter is insoluble in chlorinated lime, but soluble in hydrochloric acid. Further, if the deposit of arsenious oxide be converted into arsenic acid by the addition of nitric acid, and the latter be treated with ammonio-nitrate of silver, the brick-red arsenite of silver will be formed, affording another proof of the presence of arsenic. On placing the flame of a large spirit-lamp just below the horizontal tube, which should have been contracted after heating it in several places, when it becomes nearly red hot a deposit of metallic arsenic will be formed just in advance of the flame, the deposit continuing to increase until it may occupy the whole of the contracted space, or even part of the tube in advance of the latter. This deposit constitutes what is known as the arsenical mirror, and should be exhibited in court as proof that arsenic had been found. Reinsch's test consists in boiling bright strips of copper in a hot solution of the suspected substance previously acidulated by hydrochloric acid. Metallic arsenic being deposited upon the strips of copper, the latter are then withdrawn and placed in a reduction-tube and the presence of arsenic demonstrated in the manner already described. MEDICAL JURISPRUDENCE AND TOXICOLOGY. 209 The freedom from arsenic of the copper strips used in Reinsch's test is shown by the faet that they are not tarnished after having been boiled in hydrochloric acid. As antimony and mercury can be determined in the same manner as arsenic by tin's test, it should be men- tioned that the deposit of antimony is violet, its sublimate amorphous and insoluble in water; that of mercury bright and silvery, its sublimate consisting of bright metallic globules; that of arsenic is steel-gray, its sublimate con- sisting of octahedral crystals slightly soluble in water. Aceto-arsenite of copper or Brunswick green, also known as Vienna emerald or Paris green, not unfrequently causes death by poisoning, this pigment being extensively used in the staining of wall-paper, toys, bonbon papers, in coloring artificial flowers, articles of dress, bonnets, etc. Cases of arsenical poisoning from this pigment are usually chronic in character, resulting from living in rooms whose walls are covered with this green paper, the fine dust from which, getting into the lungs, produces the poisonous ef- fects. Death may also result from overdoses of Fowler's solution or liquor potassae arsenitis, from arsenic acid, Scheele's green or arsenite of copper, and orpiment, or the yellow sulphide of arsenic. Poisoning by Antimony. — Of the different preparations of antimony the potassio-tartrate, or tartar emetic, is the most important medico-legally, though the chloride is not unfre- quently also a cause of death. The symptoms of antimonial poisoning are a strong metallic taste during the act of swal- lowing, heat, soreness, and constriction of the throat, pain in the stomach, followed by nausea, vomiting, and diarrhoea. The pulse is quick and small, the skin is cold and clammy, cramps are often present in the extremities. The urine is often increased in quantity, but voided with pain. Death 14 210 A MANUAL OF may take place during the stage of prostration, which is very intense, or may be preceded by delirium and con- vulsions. Insensibility is sometimes produced by the taking of large doses. Cases of chronic poisoning by anti- mony are characterized by great weakness and exhaustion, accompanied by nausea, vomiting, and purging. In cases of antimonial poisoning, should vomiting not have been induced by the poison, the fauces should be tickled and hot water and milk administered, the stomach-pump being used as a last resource. As soon as the poison has been removed from the stomach strong coffee should be given, followed by opium. The antidotes are any substances that contain tannin, such as cinchona bark, .green tea, infusion of nutgalls, and decoction of oak bark, etc. As well known, infants and young children tolerate large doses of tartar emetic, espe- cially when suffering from diseases of the larynx and lungs. Three-quarters of a grain has nevertheless proved fatal in a child, and two grains in an adult. 1 The recov- eries reported after the taking of large doses were without doubt due to the poison having been rejected by the stom- ach, vomiting having been promptly induced. Death may take place within a period varying from a few hours to a few days, though it may not take place for many months. The post-mortem appearances usually found are inflamma- tion of the mucous membrane of the stomach and intes- tines, and in some cases of the brain and lungs. The liver is frequently enlarged and softened, and appears to have undergone a fatty degeneration. In the extraction of tartar emetic from the stomach the contents of the latter should be diluted with water, filtered, 1 For the different properties of arsenic and antimony, see Wharton and Stille, op. cit., vol. ii. p. 201. MEDICAL JURISPRUDENCE AMi TOXICOLOGY. '211 and acidulated with tartaric acid, and then sulphuretted- hydrogen gas passed through the liquid, by which means the orange sulphide of antimony, which is soluble in sul- phide of ammonium, will he precipitated. Should anti- mony fail to be detected by this method, then Marsh's or Ilcinsch's test should be tried. Antimony is absorbed in the system, and may be found in the viscera, blood, urine, the same methods being made use of as iu the case of arsenical poisoning. If the quantity of antimony sus- pected to be present is very small, a coil of pure zinc- foil wound around a platinum foil may be suspended in a weak acidified solution, when the metallic antimony will be deposited upon the platinum. The deposit so obtained should then be washed and digested in nitric acid until it is dissolved, and the solution then evaporated. The residue, being acidified, should then be treated with sul- phuretted hydrogen. It may be mentioned, in this con- nection, as tartar emetic is very often prescribed medici- nally, that the medical examiner should be very cautious in attributing death to poison in case of finding this salt in the stomach, unless it were obtained in quantity far ex- ceeding that of ordinary doses. The symptoms and post-mortem appearances presented in cases of poisoning by chloride or butter of antimony resemble rather those produced by mineral acids than by tartar emetic. Chloride of antimony when thrown into water yields a copious white flaky precipitate, the oxy- chloride or powder of Algaroth. The latter is soluble in tartaric acid, and turns orange-red when touched by sul- phide of ammonium. Poisoning by Merem*y. — While all the mercurial com- pounds, corrosive sublimate, calomel, red and white precip- itates, red oxide, etc., are more or less poisonous, mercuric 212 A MANUAL OF chloride or corrosive sublimate, from a medico-legal point of view, is the most important. The symptoms in cases of acute mercurial poisoning ap- pear usually immediately after the poison is taken, a burn- ing pain being at once felt extending from the throat to the stomach. The face becomes flushed. The mouth and tongue look white and shrivelled, as if they had been thoroughly painted with silver nitrate. The breathing is difficult, the pulse thready. The abdomen is painful and swollen, the pain being increased upon pressure. The stools are bloody. The thirst is intense, and a white, stringy, or bloody mucus is vomited. The urine is more or less suppressed. The skin is cold and clammy. Sali- vation usually sets in about the third day. Death gene- rally takes place soon from collapse, though it may be pre- ceded by convulsions and coma. The antidotes, white of egg, or wheat flower mixed with milk, should be given at once, and in most cases continued two or three times daily for some weeks. The white of one egg may be considered as sufficient to neutralize four grains of corrosive subli- mate. As the vapors of mercury are poisonous when in- haled, it not unfrequently happens that those who are en- gaged in working mercurial ores, in looking-glass plating, water-gilders, barometer-makers, are poisoned in this way, the fumes being given off from the metal even at ordinary temperatures. Such cases are usually chronic in character. The symptoms begin with nausea and vomiting. Coppery taste in the mouth and pains in the stomach are constantly occurring. The breath becomes fetid and swallowing diffi- cult. A hacking cough sometimes follows, with haemoptysis. Ultimately salivation becomes very noticeable. The mar- gins of the gums sometimes present a blue line like that ob- served in lead-poisoning, the gums being red, painful, swol- MEDICAL JURISPRUDENCE AND TOXICOLOGY. 213 Ion, and eveu ulcerated. Tremors and convulsive move- ments of the limbs finally become well marked, and the patient, soon dies unless actively treated. The smallest quantity of corrosive sublimate known to have proved fatal is three grains. 1 Death usually takes place within a period varying from three to six days, though it has oc- curred within half an hour in some cases, and been pro- tracted in others more than two weeks. On post-mortem examination the salivary glands are found enlarged. The abdomen is usually tympanitic. The mucous membrane of the mouth and throat presents a grayish-white color, at times being exceedingly inflamed or corroded, or even in a sloughy condition. The stomach is often very much inflamed, and is frequently covered with a slate-colored layer of finely-divided mercury, or, in cases of putrefaction, with a black precipitate of sulphide of mercury. The intestines and urinary bladder are often also much inflamed. In order to determine the presence of mercury in the stomach the contents of the latter should be mixed and crushed in a mortar, alcohol being added to facilitate filtration. The mixture, being acidified with hy- drochloric acid aud gently warmed, should then be fil- tered, and the filtrate tested by sulphuretted hydrogen and Reinsch's test. In order, however, to obtain corrosive sublimate from the stomach, the contents should be con- centrated by evaporation, and then shaken with a large bulk of ether, which is a powerful solvent of corrosive sublimate. The ether must then be carefully decanted and distilled at a gentle heat, the residue being then appropri- ately tested. Corrosive sublimate may be found in the urine within two hours and in the saliva within four hours after the taking of the poison. In examining the 1 Taylor: op. cat., p. 141. 214 A MANUAL OF urine about fourteen ounces should be evaporated down to one ounce and acidified and filtered. The filtrate should then be boiled with a piece of bright copper and placed in a reduction tube. The saliva may be tested by observing whether a piece of bright copper becomes tar- nished when placed in saliva acidulated with hydrochloric acid. Among the tests for the mercurous salts may be mentioned liquor calcis, which throws down a black pre- cipitate (black wash). Iodide of potassium gives an olive- green precipitate, chromate of potassium gives a bright red precipitate. With mercuric salts liquor calcis gives a yel- low precipitate (yellow wash). With corrosive sublimate liquor ammonias gives a white precipitate. Iodide of po- tassium gives the scarlet iodide of mercury. From a medico-legal point of view it is important for the practitioner to bear in mind that the symptoms of mercurial salivation closely resemble those due to cancrum oris or gangrene of the mouth, as suits for damages have been brought against physicians by their patients on the charge that they had been poisoned by the mercury admin- istered, when they were really suffering from one or other of the diseases just mentioned. 1 Indeed, suits for mal- practice have been instituted in which it was afterwards shown that no mercury in any form whatsoever had been prescribed. In cases of this kind the chemical analysis of the saliva would at once settle the question. Poisoning by Lead. — The most important salts of lead, from a medico-legal point of view, are the acetate and carbonate, though other preparations of lead are used for medicinal purposes. Cases of acute lead poisoning are very rare, and when they occur result from accident. Soon after swallowing acetate of lead, or sugar of lead, a 1 Christison: op. cit., p. 412. MEDICAL JURISPRUDENCE AM) TOXICOLOGY. 215 metallic taste, dryness in the throat., and thirsi are expe- rienced. The most prominent symptom, however, is severe colicky pain, which is intermittent, but is relieved by pres- sure. Constipation is invariably present, the muscular coat of the intestines being paralyzed. The urine is scanty and red, cold sweats, cramps, paralysis of the lower extremities, appear as the case progresses, followed often by tetanic spasms and convulsions. In treating cases of acnte lead poisoning emetics should be given, and if vomiting should not be induced by these means then the stomach-pump should be resorted to. The antidotes are the soluble alkaline and earthy sulphates ; the sulphate of magnesium is the best, and should be ad- ministered with eggs, opium being given to allay pain. The amount of acetate of lead that would prove fatal, and the length of time that would elapse before death took place, are uncertain. Cases of chronic or slow lead poi- soning or saturnine poisoning are of very frequent occur- rence, owing to the various ways in which lead in one form or another may be introduced into the system. It may be swallowed in drinking-water or applied in the form of cosmetics or hair-dyes, or inhaled in the form of fumes, as by artists, painters, plumbers, aud workmen engaged in the manufacture of white-lead. 1 The symptoms that appear first in chronic cases are col- lectively known as lead colic, among which the blue line at the margin of the gums is very characteristic, aud those later as lead palsy. On post-mortem examination in cases of acute lead poisoning, inflammation of the alimentary canal may be found ; but, not unfrequently, no lesion of any kind is present. In cases of chronic poisoning no special lesion is found, with the exception that the intes- 1 Guy and Ferrier : op. cit., p. 494. 216 A MANUAL OF tines are usually in a contracted condition and the muscles specially affected flabby. Lead, however, is found in the bones, brain and spinal cord, and viscera. In extracting lead from the stomach the contents should be treated with dilute nitric acid in order to form nitrate of lead, the latter being then treated with sulphuretted hydrogen. If the lead has, however, been rendered insoluble by any organic matters normally present, or by the antidotes, then the contents of the stomach should be first incinerated, and the ash treated in the manner just mentioned. The black' precipitate so obtained can be shown to contain lead by reducing it by means of charcoal and the blow-pipe. Poisoning by Copper. — The salts of copper are rarely used for homicidal or suicidal purposes. Most cases of poisoning by copper result from accident, being caused, for example, by keeping food, or cooking, in copper vessels. Green car- bonate of copper, or natural verdigris, is formed under such circumstances, and is very poisonous. All the salts of copper are poisonous. The sulphate, or blue vitriol, and the subace- tate or artificial verdigris, are the most important from a medico-legal point of view. In large doses sulphate of copper is a powerful emetic ; fatal results are often on that account prevented, the poisonous matters swallowed being at once rejected by the stomach. Among the other symp- toms presented are thirst, abdominal pain, purging, sup- pression of urine, jaundice. In cases of copper poisoning, vomiting should be induced, or the stomach-pump resorted to in case the poison has not produced that effect. White of egg, mixed with eggs and milk, should be freely ad- ministered. On post-mortem examination the body will be found to present a yellow color. The mucous mem- brane of the stomach is usually inflamed, and its contents are of a blue color. An ounce of sulphate of copper has MEDICAL JURISPRUDENCE AND TOXICOLOGY. 217 proved fatal ; but the quantity necessary to destroy life, as well as the period at which death occurs, is variable. 1 In extracting a salt of copper the contents of the stomach should be evacuated and treated with dilute hydrochloric acid and filtered; the filtrate being then treated with sul- phuretted hydrogen. The blackish-brown precipitate of sulphide of copper should then be converted into the nitrate by the addition of nitric acid, and the latter salt tested. A convenient test for salts of copper is liquor am- monia?, which gives a blue precipitate; the latter, when dissolved in an excess of ammonia, forms a beautiful sap- phire-blue. Poisoning by Zinc, Bismuth, etc. — Cases of poisoning from zinc are comparatively rare. Of the different preparations, the sulphate and chloride, the latter often used as a disin- fectant, need only be considered. The symptoms of poison- ing by zinc resemble those due to sulphate of copper. Half an ounce to an ounce has proved fatal. In some instances death has occurred within fourteen hours. The post-mortem appearance presented is inflammation of the alimentary canal. The best antidote is albumen. Bismuth, more particularly the subnitrate, deserves mention on ac- count of its being frequently adulterated with arsenic. Indeed, the finding of arsenic, when the cause of death was alleged to be poisoning, has been accounted for on the supposition that it was given in the subnitrate of bismuth administered. 2 With respect to the prepa- rations of chromium, it should be mentioned that not unfrequently fatal cases of poisoning have resulted from persons eating cakes and buns colored yellow by means of chromate of lead. Although the various preparations of 1 Woodman and Tidy : op. cit., p. 175. 2 Wharton and Stille: op. cit., vol. ii. pp. 283, 571. 218 A MANUAL OF tin, iron, silver, gold, and manganese may all prove fatal when taken in large doses, as they are so unlikely to be used for poisoning purposes, and of thus becoming the subject of medico-legal inquiry, their special consideration can be dispensed with. Poisoning by Oxalic Acid. — Of the irritant poisons of vegetable origin, oxalic acid is the most important. Resembling sulphate of magnesium or Epsom salts, for which it is readily mistaken, and being easily procured either as oxalic acid' or as salt of sorrel, salt of lemons, potassium oxalate, it is not unfrequently taken by acci- dent or for suicidal purposes. The symptoms of poisoning by oxalic acid are a hot, burning, acid taste during swal- lowing, followed by pallor, clammy perspiration, extreme prostration, abdominal pain, accompanied with vomiting. If the poison be diluted, the vomiting may be protracted. In some cases, however, there is no vomiting at all ; in others it may continue incessantly until death The nerv- ous system appears to be also remotely affected, as, in cases of recovery from oxalic acid poisoning, spasmodic twitch- ings of the facial muscles, temporary loss of voice, numb- ness and tingling of the legs have been observed In treating cases of oxalic acid poisoning, magnesia, plaster from the walls, chalk or carbonate of calcium, should be given ; the last is the best remedy, as it forms with oxalic acid the inert calcium oxalate. Vomiting should after- ward be induced by an emetic of sulphate of zinc. Alka- lies and their carbonates should not be given, however, under any circumstances, as the salts formed would be as poisonous as the oxalic acid. The mucous membrane of the mouth, tongue, and throat appears as if bleached. The stomach is often black, and even gangrenous, though per- foration is rare. It often contains a dark-brown liquid. MEDICAL JURISPRUDENCE AND TOXICOLOGY. '21 9 One drachm of oxalic acid lias proved fatal. 1 Death may take place very quickly, or may be protracted several days. Through the addition of acetate of lead to the contents of the stomach previously filtered oxalate of lead is precipi- tated; the latter being treated with sulphuretted hydrogen, oxalic acid is set free and the lead is precipitated as sul- phide of lead. A convenient test for oxalic acid is calcium sulphate, which gives a white precipitate of calcium oxalate soluble in mineral, but insoluble in vegetable acids. It may be mentioned, in this connection, that both tartaric and acetic acids have proved fatal when taken in doses of an ounce. In the treatment of such cases, magnesia, chalk, or the alkaline carbonates may be given. Poisoning by Carbolic Acid. — Carbolic acid, sometimes called coal-tar creasote, is so extensively used as an anti- septic and is so powerful a poison that it demands at least brief mention. The symptoms of poisoning are vertigo and intoxication, accompanied by intense burning pain in the mouth and stomach, with vomiting of frothy mucus. The pupils are contracted ; the pulse rapid and intermittent. The urine is frequently suppressed ; what- ever is passed is dark-colored and smoky ; convulsions and coma often supervene. In treating such cases oil and de- mulcent drinks, sulphate of sodium or Glauber's salts may be administered, and the stomach-pump should be used. With any treatment, however, there is but little chance of recovery. Six or seven drops having caused the most dan- gerous symptoms, it is to be expected that death will follow almost immediately after the taking of any large quantity. Indeed, death has been known to take place within ten minutes after swallowing about an ounce of car- 1 Taylor : op. cit., p. 105. 220 A MANUAL OF bolic acid, though life may be protracted two or three days. 1 As a general rule, after death the mouth, oesophagus, and stomach are found white and corroded. The lungs are usu- ally found much congested ; the brain occasionally so. Car- bolic acid can be usually found in the urine by agitating the latter with an excess of ether, removing the ether by means of a pipette and evaporating. The minute oily residue left has the character of that acid. The best gen- eral test for carbolic acid is probably its odor. Poisoning by Vegetable Substances. — There are a number of well-known substances, such as croton oil, the oil of Fig. 44. Fig. 45. Leaf of the Croton tiglium. Colchicum autumnale : a, flower- ing plant ; b, stigmas ; c, leaves and fruit. the seed of Croton tiglium (Fig. 44), ergot of rye, the fool's parsley {JEthusa cynapium), elaterium obtained from 1 Woodman and Tidy : op. cit., p. 516. MEDICAL JURISPRUDENCE AND TOXICOLOGY. 221 the wild cucumber, water dropwort {CEnanihe crocata), castor-oil beans, seeds and wine of colchicum (Fig. 45), cow bane (Ciouta virosa), oil of savin procured from the toys of juniperus sabina, yellow jessamine, veratrum viride, and the other species of hellebore, all of which possess poisonous properties of an irritant character. As cases of poisoning by these substances arc usually accidental in character and unlikely to become the subject of medico- legal inquiry except in the case of oil of savin often used as an abortive, it will' not be necessary to dwell upon their characteristic properties. Poisoning by Eating Fungi. — The symptoms caused by eating poisouous fungi, often resembling those due to poison administered with homicidal intent, demand some consider- ation on the part of the medical jurist. As is well known, while certain fungi may be eaten usually with impunity, there are others which invariably prove poisonous. The symptoms which follow the eating of poisonous mushrooms, and which usually appear within an hour, are giddiness, thirst, abdominal pain, vomiting, purging, sweats, dimness of vision, delirium, convulsions, and coma. 1 Death usually takes place within twenty-four hours. In treating such cases the stomach-pump should be used and an emetic of sulphate of zinc and castor oil should be administered. On post-mortem examination the stomach and intestines are usually found inflamed and may even be gangrenous. The contents of the stomach should be carefully searched for the gills and spores of the mushroom suspected to have been the cause of poisoning, the particular fungus being by these means identified. Poisoning by Decomposed Food. — The irritant poisons of animal origin are cantharides and the poisons devel- 1 Casper : op. cit., vol. ii. p. 61. 222 A MANUAL OF Cantharis vesicatoria (Spanish fly). oped under certain circumstances in food. The symp- toms of poisoning from the powdered Cantharis vesica- toria (Fig. 46), or the tinc- Fig. 46. ture of cantharides, are pain in swallowing, a burning sensation in the mouth and stomach, thirst, vomiting, and bloody stools, priapism, inflammation and swelling of the genitalia, and occa- sionally convulsions and de- lirium. In treating a case of poisoning from such a cause, emetics and thick warm liquids should be administered, opiates should be given in the form of enema, and suppositories and leeches applied. On post-mortem examination the mu- cous membrane of the alimentary canal and urino-genitary tract will be found inflamed. Portions of the wings and wing-cases of the insect, which resist putrefaction for a long time, should be looked for, especially in the large in- testine. An ounce of the tincture of cantharides has proved fatal, death taking place in twenty-four hours. Poisoning by Micro-organisms, Bacteria, etc. — Apart from trichinosis produced by eating raw pork, the mus- cular tissue of which is infested with the minute worm, the Trichina spiralis (Fig. 47), poisonous effects are fre- quently produced by eating food in a state of putrefaction induced by micro-organisms, bacteria, etc., or food con- taining ptomaines or " cadaveric alkaloids," so called on account of the manner of their production and of their effects when introduced into the system. The poison- ous effects frequently produced by eating meat, sausage, MEDICAL JURISPRUDENCE AND TOXICOLOGY. 22-i cheese, fish, mussels, and puff-paste, appear to be due to the presence of either micro-organisms or ptomaines. 1 The symptoms and post-mor- Trichina spiralis, coiled within its cyst (X50). tern appearances in all such Fig. 47. cases are those of an irritant poison — giddiness, nausea, cramps, vomiting, purging — the mucous membrane of the alimentary canal being found inflamed. As to what par- ticular micro-organism should be attributed the changes de- veloped in food, making it poisonous ; as to the exact na- ture of the ptomaines which cause poisoning when intro- duced into the system in some persons, but give rise to no inconvenience whatever in others, considerable difference of opinion still prevails among bacteriologists and. toxicolo- gists. It is to be regretted, particularly from a medico- legal point of view, that so little has been definitely estab- lished with reference to the nature of such organisms and poisonous principles, inasmuch as attempts have been made in cases of undoubted poisoning to account for the latter on the supposition that the person was poisoned by the food eaten rather than by the poison actually adminis- tered with homicidal intentions. Neurotic Poisons. — With opium we begin the consid- eration of neurotic poisons, or that class of poisons which affect more particularly the great nervous centres — the brain and spinal cord. The symptoms produced by neu- 1 Fliigge : op. cit., p. 567. 224 A MANUAL OF rotic poisons are usually headache, giddiness, drowsiness, stupor, delirium, convulsions, paralysis, there being, how- ever, little or no inflammation of the mucous membrane of the alimentary canal, as was seen to be so common in cases of poisoning by irritants. The post-mortem changes in cases of neurotic poisoning are but few, and not well marked — more or less fulness of the cerebral vessels being observed, but rarely accompanied with effusion of serum or blood in the brain. Cerebral Neurotic Poisons. — Poisoning by Opium. — In addition to the different preparations of opium that are used medicinally there are a number of patent medi- cines which contain this drug or some of its alkaloids, among which may be mentioned Godfrey's cordial, Dalby's carminative, Winslow's soothing syrup, Locock's pulmonic wafers, Battley's liquor, etc. It is on this account that so many cases of poisoning are due to opium, the drug being taken, in one form or another, either accidentally or suicidal- ly, or administered to others with homicidal intent. Opium, the concrete juice of the unripe capsule of the poppy {Papaver somniferum ; JFig. 48), is a complex sub- stance containing a number of active principles, the chief of which are morphia, me- conic acid, narcotina, codeia, narceine, thebaine, papaver- ine. From a medico-legal point of view, however, morphia and meconic acid are the most important of these principles, as by their reactions the presence of opium is recognized. Papaver somniferum (capsule of the opium poppy). MEDICAL JUKISPKUDENCE AND TOXICOLOGY. 225 The symptoms of opium poisoning arc giddiness, drowsiness, stupor, profound sleep, flushed face, slow and stertorous breathing, eyes closed and pupils contracted, in- sensible to light, pulse rapid and small or dec and slow, skin moist and cool. The patient, from being aroused and kept awake only with difficulty, soon passes into a completely comatose condition, death taking place from apoplexy, collapse, convulsions, though usually tran- quilly. These symptoms miay appear within a few minutes after taking the drug, or be protracted for several hours, accord- ing to the condition of the system and the mode of ad- ministration; opium, as is well known, acts more powerfully on a full than an empty stomach, when the person is at rest than when taking exercise, and in a liquid rather than in a solid form. The effects of taking opium habitually and for a long time are emaciation, loss of appetite, con- stipation, failure in mental and physical vigor, neuralgic pains, premature old age, and death. The smallest quantity of opium known to have produced death is four grains. 1 The amount that can be taken without producing death, however, by those persons habitually using opium is almost incredible. Indeed, over four thousand drops of laudanum have been taken daily by a person with whom the author is intimately acquainted, and De Quincey is said to have taken as much as nine ounces. Death may take place within an hour or be delayed several hours. If the patient survives over twelve hours, the chance of recovery is good. The post-mortem changes in cases of opium poisoning are neither well-marked nor constant. Occasionally the cerebral vessels are found in a turgid condition, with some 1 Christison : op. cit., p. 713. 15 226 A MANUAL OF sub-arachnoid effusion of serum at the base of the brain or around the spinal cord. In treating cases of poisoning by this substance, the opium should be removed by means of the stomach-pump as soon as possible, or by an emetic such as sulphate of zinc or mustard water. Cold water should be dashed over the face and chest in order to overcome the increasiug lethargy. Strong coffee should also be administered, and the patient, to be kept aroused, must be made to walk between two attendants. Atropia should be administered hypodermat- ically, the effects upon the pupils being carefully watched. Should all such remedies fail, then electro-magnetism may be resorted to. The symptoms of poisoning by morphia, the most important of the principles of opium, differ only from those produced by the drug itself in manifesting themselves sooner and in tending to produce convulsions more frequently. One grain of morphia has in more than one instance proved fatal, and less than a grain when ad- ministered hypodermatically. 1 The external application of morphia has also been followed by fatal results when applied externally to an abraded surface. The post-mortem ap- pearances presented in cases of morphia poisoning do not differ from those already described as being caused by opium. There is no direct chemical test for opium. As every watery solution contains, however, meconate of morphia, if the latter salt can by any means be shown to exist in the contents of the stomach, the vomit, or the tissues, then in this indirect way the presence of opium may be considered as having been demonstrated. The principle of the analy- sis is based upon the possibility of decomposing the meco- nate of morphia that may be present, and then re-obtaining 1 Wharton and Still4 : op. cit., vol. ii. p. 338. MEDICAL JURISPRUDENCE ANJ) TOXICOLOGY. 227 tlio acid and salt constituting the alkaloid ' as meconate of lead and acetate of morphia. The process consists in fil- tering the contents of the stomach — any solid matters being finely divided and well mixed with liquid. If acetic acid be added and then acetate of lead, meconate of lead will be precipitated, acetate of morphia remaining in solution. The mixture is then filtered and tested in the following manner : The solution containing the acetate of morphia is divided into two parts. To one part is added a solution of perch lo- ride of iron, by which a greenish-blue color is produced. To the other part, evaporated to dryness, nitric acid is added, by which a yellow color becoming orange-red is developed. The precipitate containing the meconate of lead is diffused in water, through which sulphuretted hy- drogen is then passed, by which sulphide of lead is pre- cipitated and meconic acid left in solution. To the latter, on the addition of perchloride of iron, a blood-red solution will be formed. It must be remembered, however, that even in cases where there was every reason to suppose that opium had been given, and when the analysis was made with the greatest care, not a trace of either meconic acid or morphia could be found. Poisoning by Alcohol. — The poisonous effects of alcohol are either of an acute or chronic character. The symp- toms of acute alcoholic poisoning are unsteadiness of gait, incoherent talking, stupor, and coma. The features have a vacant expression, or may be suffused and bloated. The lips are livid, the pupils are unusually dilated, bloody froth appears upon the lips, the breathing becomes difficult and then stertorous. In treating such cases emetics should be administered, or the stomach-pump used, cold affusions 1 For a detailed account of the methods of detecting alkaloids in sus- pected matters, see Wharton and Stille, op. cit., vol. ii. p. 35-4. 228 A MANUAL OP employed, and ammonia and coffee given. On post-mortem examination the mucous membrane of the alimentary canal, the lungs and brain may be found congested, with serous effusion under the arachnoid and in the ventricles. Alcoholism, or chronic poisoning by alcohol, as already mentioned, is the proximate cause of numerous diseases, such as cirrhosis of the liver, fatty liver, epilepsy, gastritis, disease of the kidneys. Alcoholism indirectly favors the production of, and the mortality of, disease in general by diminishing the resisting power of the system. The per- ceptions finally become blunted, the moral and intellectual faculties are perverted by its habitual use, until at last the victim becomes a dipsomaniac. Alcohol can be obtained from the stomach by distillation. The contents of the stomach, if acid, having been neutralized by sodium car- bonate, should be distilled. The distillate, having been mixed with calcium chloride, must be then redistilled. The second distillate should then be shaken up with dry sodium carbonate, the supernatant fluid being drawn off for testing purposes. Poisoning by Ancesthetics. — The cerebral neurotics in- clude the anaesthetics ether, chloroform, and chloral hydrate. The symptoms produced by ether are very much the same as those of alcohol. When inhaled, slow, prolonged, ster- torous breathing results, the surface of the body feels cold, the lips become blue, the face pale. The pulse is at first accelerated, but is afterward slowed. The muscles become relaxed. The eyes are fixed and glassy, the pupils dilated. Anaesthesia becomes deep, coma following with entire loss of sensation. Nausea and vomiting frequently occur. In poisoning by liquid ether, the stomach-pump should be employed, emetics being given afterward. When inhala- tion has been carried too far, the patient should have plenty MEDICAL JURISPRUDENCE AND TOXICOLOGY. 229 of fresb air, cold affusions should be applied, and artificial respiration and galvanism resorted to. Congestion of brain and lungs, and the heart-cavities filled with liquid dark blood, are usually found upon post-mortem examination. The mode of extracting ether from the contents of the stomach is the same as that made use of in the case of alcohol. The symptoms produced by chloroform when swallowed are those of an irritant poison, but when inhaled the symptoms resemble those caused by ether, but appear much more rapidly. Death is caused by paralysis of the respiration and circulation, the nerve-centres being prob- ably directly affected, as death in some cases is almost in- stantaneous. In treating cases of chloroform poisoning, if the chloroform has been taken in a liquid form, an emetic should be resorted to, or the stomach-pump used, and stimulants administered. If the chloroform has, however, been inhaled, with the first dangerous symptoms it should be instantly discontinued and fresh air admitted, as a few drops of chloroform may prove fatal in as many seconds. Water should be dashed in the face, the tongue pulled out, artificial respiration practised, and the galvanic current applied. The post-mortem appearances presented in cases of chloroform poisoning are those of death due to as- phyxia. Chloroform can be extracted from the stomach by distillation and tested by passing the vapor through flame, by which it will be decomposed into carbon, hydrochloric acid, and chlorine. The carbon will be recognized by its black deposit, the acid by reddening litmus, and. the chlorine by applying starch-paper dipped in a solution of potassium iodide ; the latter being decomposed and the iodine set free, the starch will become blue. Chloral hydrate, so much used at the present day to 230 A MANUAL OF procure sleep, is on that account not iufrequently a cause of death, over-doses being taken accidentally. In cases of poisoning by it the face becomes flushed ; the pupils, at first contracted, are then dilated ; the pulse is quick ; profound sleep is induced, which passes rapidly into coma through cessation of the circulation and respiration. The action of chloral hydrate may be possibly due to its decom- position in the system, probably in the blood, into an alka- line formiate and chloroform. As thirty grains of chloral hydrate have proved fatal, that amount can hardly be con- sidered a safe dose to begin with. Nevertheless, as much as an ounce has been taken at once with impunity. Among the cerebral neurotics should be included carbon monoxide and carbon dioxide, as the effects of both these gases when inhaled are very similar to those produced by narcotic poisons. Carbon monoxide is produced when charcoal is burned, and frequently collects in pits, cellars, wells, and mines. Carbon dioxide, as is well known, is one of the principal products of respiration. The symptoms of poisoning by both these gases are essentially the same — giddiness, headache, drowsiness, insensibility, and coma being the most prominent. In treating cases of carbon monoxide poisoning vene- section and transfusion of arterialized, defibrinated blood should be tried. In cases of poisoning by carbon dioxide the patient should be given plenty of fresh air, the cold douche, galvanism, and stimulants applied, artificial respi- ration practised, etc. It will be found much more difficult, however, to revive a person affected by carbon monoxide gas than by carbon dioxide, the poisonous effects of the latter being transitory, whereas carbon monoxide in dis- placing the oxygen of the blood and forming a somewhat stable compound with the haemoglobin renders respiration MEDTCAL JURISPRUDENCE AND TOXICOLOGY. 231 very difficult. Suicides are frequently committed, more especially in France, by inhaling charcoal vapor; and death is often caused accidentally in America in the same way, as in those cases where persons have gone to sleep in a room with a charcoal fire burning without a flue. The absorbing effect of carbon monoxide blood upon light transmitted through it has already been referred to in connection with the spectroscopic examination of blood. Spinal Neurotic Poisons. — Poisoning by Strychnia. — Strychnia, one of the most important of poisons on account of being so frequently taken accidentally or suicidally, as well as given with homicidal intent, exists, together with brucia, in the seeds of the strvchnos mix vomica, a tree found in India, The seeds owe their poisonous properties to these two alkaloids, and as the symptoms of poisoning, etc., by nux vomica are the same as by strychnia, we may pass at once to the consideration of the latter — merely mentioning that thirty grains of nux vomica, about the weight of one seed, and three grains of the alcoholic ex- tract have proved fatal. 1 Strychnia is not ouly used medici- nally, but is readily obtainable otherwise, entering largely into the composition of the so-called " vermin-killers," Battley's vermin-killer containing as much as 23 per cent. The first symptoms of strychnia poisoning, appearing usually within from ten to twenty minutes after it is taken, are a general uneasiness and restlessness, followed by a feeling of suffocation. The muscles begin to twitch and the head and limbs to jerk, and then violent tetanic con- vulsions come on, involving the whole body. The legs are stretched out stiffly and separated, the feet arched and turned in, the arms are flexed and drawn across the chest. The head and body are so bent back that opis- 1 Christison : op. cit., p. 201. 232 A MANUAL OP thotonos supervenes, the patient resting upon his head and heels. The respiratory movements are arrested by the muscular spasm, the face becomes livid, the pupils dilated. The muscles of the mouth are so contracted as to give rise to a broad grin, the risus sardonicus, and lockjaw is fre- quently present, though one of the later symptoms. In- tense thirst may be experienced. The paroxysm may last from half a minute to several minutes; subsiding, it is followed by relaxation, the patient being bathed in perspi- ration and utterly prostrated. In a short time, sometimes within a few minutes, the paroxysm returns, being brought on by the slightest cause — a breath of wind, a slight noise, an effort to move. It increases in frequency and violence; death results usually in between five and six hours from asphyxia or exhaustion, the mind remain- ing clear almost to the last. As small a quantity as the one-sixteenth of a grain of strychnia has proved fatal in a child, and one-half of a grain in an adult. 1 It should be mentioned that the action of strychnia, when administered hypodermatically, is far more powerful than when given by the mouth. In the treatment of strychnia poisoning, emetics should be given at once, and the stomach-pump used if the lockjaw permits of it. Lock- jaw can sometimes be overcome by chloroform, the ad- ministration of which is often attended in other respects with good results. The thirst can be relieved by strong tea better than by anything else. Calabar bean, on account of being a spinal depressant, should be tried ; and bromide of potassium in large doses, morphia, atropia, chloral hydrate, nitrite of amyl may also prove efficacious as antidotes. On post-mortem examination the brain and spinal cord 1 Taylor : op. cit., p. 217. MEDICAL JTJEISPRtTDENCE AND TOXICOLOGY. 233 may be found very much congested, with effusion of blood. Rigor mortis may be prolonged for several weeks after death. In extracting strychnia from the stomach the organic mixture should be first acidified with acetic acid, and sufficiently diluted to make filtering easy. The fil- trate, having been evaporated to the consistency of a syrup, should be then heated with eight or ten times its bulk of alcohol, and again filtered, the liquid being distilled off. The filtrate should then be saturated with liquor potassse and shaken up with its own bulk of ether. The acetate of strychnia, previously formed, being now decomposed by the potassa, the strychnia is precipitated and is taken up by the ether. Any coloring-matter present may be re- moved by sulphuric acid. In order to insure the perfect purity of the strychnia the above process should be re- peated two or three times. Strychnia may be recognized by its bitter taste, by the tetanic convulsions that it pro- duces when injected subcutaneously into a frog, and by the play of colors it exhibits in the presence of nascent oxygen. It is probably the bitterest substance known. Indeed, only one grain gives a bitter taste to a gallon or even more of water. In the absence, therefore, of such substances as morphia, quinia, aloes, colocynth, quassia, characterized also by having a bitter taste, a substance possessing this quality and alleged to have caused death should certainly be tested still further for strychnia. The delicacy of the physiological test, that is, of causing convulsions in a frog by the subcutaneous injection of strychnia, may be appre- ciated from the fact that convulsions follow the injection of only T"soUU* u P ar ^ °^ a g ram > The color test is performed by adding a drop of pure sulphuric acid to a small piece of strychnia on a white por- celain surface, the strychnia, if perfectly pure, being dis- 234 A MANUAL OF solved by the acid without coloration. If a little bichro- mate of potassium, or binoxide of manganese, be now stirred into the mixture, a play of colors will be presented, succeeding each other in the following order — blue, violet, purple, pink, and finally red. It should be observed that the value of the color test depends not so much upon any particular color being developed, or upon there being a play of colors, as upon the constant order in which the differ- ent colors manifest themselves. The color test is even more delicate than the physiological one, the TooooTo^h of a grain of strychnia having been detected in this way. It should be mentioned, however, that it has been objected that there are certain substances, like morphia, which in- terfere with the color test, and that there are other sub- stances which exhibit very much the same play of colors on the addition of sulphuric acid. In reply, it may be said that those substances which interfere with the color test can be gotten rid of by using chloroform instead of ether in extracting the alkaloid from the stomach, and that Fig. 49. Fig. 50. Various forms of crystals of strychnia. Crystals of brucia. the change of color manifested by strychnia differs so much from that exhibited by other bodies on the addition of sul- MEDICAL JURISPRUDENCE AND TOXICOLOGY. 235 phuric acid that no real difficulty should be experienced in distinguishing them (Fig. 49). Brucia (Fig. 50), the remaining alkaloid of mix vom- ica, is usually found associated with strychnia. As the symptoms of brucia are the same as those of strychnia, only less intense, and as the mode of extraction from the stomach is the same in the case of both alkaloids, we need not dwell upon its special properties. It may be men- tioned, however, that it turns to a blood-red color in the presence of nitric acid, the alkaloid being speedily dissolved. Cerebrospinal Neurotic Poisons. — Poisoning by Bella- donna. — Belladonna may be considered as the type of a group of poisons the characteristic effects of which are frequently flushed face, redness of the skin, heat and dry- ness of the throat, dilatation of the pupil, illusion of the senses, and active delirium. Indeed, the latter symptom Fig. 51. is so characteristic of these poisons that the entire group is often designated on that account as " deliriauts." The group includes stramonium, hyoscyamus, different species of solanum as well as bella- donna, all representatives of the natural order of Solanaceae, and known therapeutically as mydriatics. The symptoms of poisoning by belladonna, the Atropa belladonna (Fig. 51) or deadly nightshade, ap- pearing usually within two hours of taking the substance, are giddiness, drowsiness, intense thirst, dryness of the Atropa belladonna : a, the berry. 236 A MANUAL OF mouth and throat, difficulty in swallowing, the saliva being suppressed. Vomiting and purging are rare. The action of the heart is increased, pulse rapid and strong. The face is flushed, the eyes sparkle, with pupils invariably dilated. The power of speech is lost, though there is a constant movement of the lips and tongue, as if the patient was trying to articulate. Vision is affected, if not lost, through the loss of the power of accommodation. There is frequently a desire to micturate, with inability to do so. The patient is affected with all kinds of illusions and hallucinations, and finally with delirium, which in some cases may be of a pleasing character, in others so furious as to resemble mania. Death, when it occurs, takes place usually within twenty-four hours. A few berries of belladonna or a drachm of the extract has proved fatal. 1 The symptoms of poisoning by atropia, the active alkaloid of belladonna, are the same as those of the plant itself — only manifesting themselves more quickly and acting more powerfully. One and a half grains of atropia have proved fatal. 2 In treating cases of poisoning by belladonna or atropia the stomach should be evacuated by an emetic or by means of the stomach-pump. Morphia should be administered hypodermatically. As soon as the patient shows signs of getting better, castor oil may be given and strong coffee. The post-mortem appearances presented in cases of poison- ing by atropia or belladonna are neither constant nor well marked. The pupils are dilated. The brain may be con- gested and the stomach inflamed. In cases of poisoning from belladonna, the remains of the leaves and berries should be carefully searched for in the stomach and intes- tines. Atropia can be extracted from the stomach by 1 Woodman and Tidy: op. cit., p. 210. 2 Wharton and Stille : op. cit., p. 423. MEDICAL JURISPRUDENCE AND TOXICOLOGY. 237 acidifying; the contents of the latter with acetic acid and warm alcohol and filtering. The filtrate .should then be treated with snbacetate of lead and sulphuretted hydrogen, by which the sulphide of lead is precipitated. The clear filtrate evaporated to dryness and acidified, and saturated with potassa, can be then treated with alcohol, and the extract tested. A solution of hydrobromie acid saturated with free bromine gives a yellow precipitate which soon becomes crystalline, and is insoluble in mineral acids, acetic acid, or caustic alkalies. Atropia can also be tested by applying a portion of the ultimate extract to the eye of a man or of a rabbit, the smallest quantity producing dilata- tion of the pupil. As the symptoms, treatment, etc. of poisoning by stramonium or thornapple, Jamestown weed, hyoseyamus or henbane, solanum dulcamara or bittersweet, woody nightshade, are essen- tially the same as those of Fig. 52. belladonna, it will be un- necessary to dwell especially upon them. Poisoning by Tobacco. — Among the cerebro - spinal neurotic poisons are tobacco, lobelia (Fig. 52), conia, aco- nite, Calabar bean, often con- sidered together on account of the property they possess in common of depressing the muscular system, although they may differ from one an- other in some respects. Tobacco, or the dried leaves of Xico- tiana tabacum, owes its active and poisonous properties to a Lobelia iuflata. 238 A MANUAL OF volatile liquid alkaloid, nicotina, 1 one of the most rapidly fatal poisons known, existing in Havana tobacco to an ex- tent of only two per cent., but in Kentucky and Virginia tobaccos to as much as seven per cent. The symptoms of poisoning by tobacco are giddiness, much depression and faintness, trembling of the limbs, clammy sweats, frequent vomiting, violent abdominal pains, with occasional purg- ing. The pulse becomes first weak and then almost im- perceptible ; breathing becomes difficult ; vision is affected ; death taking place with convulsions and more or less paralysis. In treating cases of poisoning by tobacco, the stomach should be evacuated as soon as possible, either by emetics or the stomach-pump. Pain may be relieved by opium and the strength should be supported by stimulants. The external application of tobacco leaves and of a decoc- tion of tobacco to the skin, as well as half a drachm given by enema, has proved fatal. Death has resulted from tobacco within fifteen minutes and from nicotina in three minutes. On post-mortem examination the stomach, liver, lungs, and brain may be found congested, but not invariably. The remains of tobacco should be looked for with a lens. The hairs found on the pieces are peculiar. In extracting tobacco from the stomach essentially the same process may be used as that described in obtaining belladonna. A con- venient test for nicotina is corrosive sublimate, which yields a white crystalline precipitate, soon changing to yellow, and soluble in acetic and hydrochloric acids. As the symptoms and post-mortem appearances caused by Indian tobacco, lobelia inflata or its active alkaloid lobelina, are very much the same as those due to the taking of ordinary tobacco, it will be unnecessary to describe them. It may 1 Tardieu : op. cit., p. 778. MEDICAL JURISPRUDENCE AM) TOXICOLOGY. 239 bo mentioned, however, that one drachm of the powdered leaves has proved fatal in about thirty-six hours. On post-mortem examination the brain was found congested and the mucous membrane of the stomach inflamed. Poisoning by conia, the active alkaloid of the spotted hemlock (Convum maculatum; Fig. 53), is generally the re- Fig. 53. Fig. 54. Conium maculatum : a, the fruit ; b, transverse section of the fruit. Aconitum napellus (aconite) : a, the root ; b, the leaf. suit of accident, the fresh leaves being sometimes used in cook- ing in mistake for parsley, which it slightly resembles. The symptoms are dryness and constriction of the throat, mus- cular prostration, pupils often dilated and vision affected, paralysis, and frequently convulsions, delirium, and coma. The post-mortem appearances presented are those of as- 240 A MANUAL OF phyxia, congestion of the brain, and inflammation of the mucous membrane of the stomach. The treatment should consist in the administration of emetics, diffusible stimu- lants, and in practising artificial respiration. Poisoning by Aconite. — The symptoms of poisoning by aconite, obtained from monkshood or wolfbane (Aconitum napettus; Fig. 54), are dryness of the throat, with tingling and numbness of the lips and tongue, followed by nausea and vomiting and abdominal pain. There are ringing in the ears and diminishing, if not loss of, vision. The power of speech is lost. Breathing becomes slow and laborious. Cold, clammy sweats are common, accompanied with great prostration. The numbness of the limbs increases until finally both ex- tremities are paralyzed. Death occurs either from shock, asphyxia, or syncope. Aconitia, the active alkaloid of aconite, is probably the most powerful poison known. In treating cases of poisoning by aconite or its active principle, an emetic of sulphate of zinc should be administered at once, or the stomach-pump used. Mustard plasters may be applied to the pit of the stomach ; and ammonia, brandy, strong tea, or coffee should be given. Digitalis should be tried as an antidote. Twenty-five minims of Flemiug's tincture and one-tenth of a grain of aconite have proved fatal. 1 Death generally takes place within three or four hours ; though it has occurred within twenty minutes, it has been delayed nearly twenty hours. On post-mortem examination there is usually found general venous congestion, especially of the brain, liver, and lungs, as well as inflammation of the mucous mem- brane of the alimentary canal. The different parts of the plant should be carefully looked for. The process of ex- traction from the stomach is essentially the same as that 1 Taylor : op. cit., p. 226; Gny and Ferrier: op. cit., p. 621. MEDICAL JURISPRUDENCE AND TOXICOLOGY. 241 described for obtaining belladonna. The characteristic symptoms produced when given to small animals, such as weakness, staggering', difficult breathing, convulsive twitch- ings, loss of sensibility, etc., constitute the most important tests for aconitia. Iodide of potassium may also be used as a test, giving with the alkaloid a reddish-brown amor- phous precipitate. Calabar bean, the seed of Physostir/ma vencnosum, owes its poisonous properties to an alkaloid, physostigma, or eseriue. The symptoms of poisoning are giddiness, fol- lowed by paralysis of the voluntary muscles, convulsive muscular twitch ings, and invariably contraction of the pupil. Owing to the latter property, atropia should be administered as an antidote. Six of the beans proved fatal in the case of a boy who had eaten them. 1 The cerebro-spinal neurotic poisons include not only the deliriant and depressant kind of poisons, but also such as usually destroy life by causing heart failure, and hence often called "asthenics." The most important of this kind of poisons are hydrocyanic acid, digitalis, and cocculus indicus. Poisoning by Hydrocyanic Acid. — Hydrocyanic or prussic acid is one of the most powerful and rapidly fatal poisons known, its effects being manifested with lightning-like rapidity. It is developed rather than pre-exists in the kernels of the peach, apricot, plum, cherry, and in the leaves and flowers of the peach and cherry-laurel through the action of water upon amygdalin and emulsin, two principles present in the plants. Pure prussic acid, being rarely found anywhere except in the laboratory of the chemist, has but little or no interest medico-legal ly. The medicinal acid, or the solution of the pure anhydrous acid 1 Woodman and Tidy : op. eit. , p. 320. 1(3 242 A MANUAL OF in water, demands attention, however, on account of death being so frequently caused by it. The symptoms produced by prussic-acid poisoning are giddiness, with immediate loss of muscular power, the person staggering and falling to the ground. The breath- ing becomes quick and gasping, the pulse imperceptible. The eyes protrude and are glassy, the pupils being dilated and insensible to light. The extremities are cold. The face becomes livid or pale. The jaws are spasmodically closed. There may be bloody frothing at the mouth, and the odor of the poison may be noticed on the breath. Death may take place preceded by coma, stertorous breath- ing, or by convulsions. Unfortunately, the poisonous effects of prussic acid manifest themselves so quickly that the opportunity is but rarely afforded for treatment. The latter, when practicable, consists in applying cold affu- sions, practising artificial respiration, placing ammonia to the nostrils. A mixture of a ferrous and ferric sulphate of iron with caustic alkali should be administered with the hope of forming the inert ferrocyanide of potassium. Emetics and the stomach-pump should also be used. On post-mortem examination the lungs, liver, spleen, and kidneys will be found gorged with blood. The brain may be found congested, and there may be effusion of serum into the ventricles. The stomach and intestines may also be found congested. The most important, con- stant, and characteristic sign noticed, however, is the dis- tinct odor of prussic acid exhaled when the body is opened and often even before it is opened. Fifty minims of the official acid, equivalent to about nine-tenths of a grain of the anhydrous acid, have proved fatal. 1 Death may occur either instantaneously or within ten or fifteen minutes after 1 Woodman and Tidy : op. cit., p. 457. MEDICAL JUBISPBUDENCE AND TOXICOLOGY. 243 Fig. 55. swallowing the poison, being rarely protracted half an hour. The general method adopted in extracting prussic acid from the stomach is to distil the contents of the latter at a gentle heat, the vapor being collected in a receiver kept cool by being placed in cold water, or to acidify the con- tents of the stomach if alkaline, and place the mixture in a vessel standing in a basin containing water at 60° F., and then testing the rising vapor. The presence of prussic acid can be recognized by the white cyanide of silver formed through application of nitrate of silver, by the white sulphocyanide of ammonium formed with sulphide of ammonium, the latter turning red on the addition of perchloride of iron, the formation of Prussian blue by add- ing liquor potassse, a proto- and per-salt of iron, and sul- phuric acid. As the symp- toms, etc. of poisoning by the cyanides, oil of bitter almonds, cherry-laurel water, the kernels of the peach, apri- cot, and cherry, essence of mirbaue, are essentially the same as those produced by prussic acid proper, only less intense, they need not be es- pecially considered. Poisoning by Digitalis. — The symptoms of poisoning by foxglove (Digitalis purpu- rea; Fig. 55), or its active alkaloid digitaline, are headache, giddiness, nausea, vomit- ing, purging, abdominal pain, dimuess of vision with dilated Digitalis purpurea leaf. 244 A MANUAL OF pupils, slow, irregular pulse. In treating cases of poisoning by digitalis emetics should be given, and infusions containing tannin, such as tea, coffee, oak bark, etc., as stimulants. On post-mortem examination the brain may be found con- gested, and the mucous membrane of the stomach inflamed. Digitalis may be extracted from the stomach by the process used in obtaining belladonna. The most reliable test for digitaline is the effect it produces upon the action of the frog's heart, causing stoppage and irregularity in the beats. Poisoning by Cocculus Indicus. — The symptoms of poi- soning by Cocculus indicus, or the berry of menispermum, or Anamirta cocculus, are gastro-intestinal irritation, accom- panied with lethargic stupor and powerlessness. The poisonous properties are due to an alkaloid, picrotoxine. Of six persons poisoned accidentally on one occasion by a decoction of cocculus indicus, two died within half an hour, the remaining four recovering after several hours. The prominent symptoms in these cases were giddiness, faintness, nausea, dimness of vision, intense thirst, and abdominal pain. 1 In conclusion, it may be mentioned that the laburnum (Qytisus laburnum), the yew (Taxus baccata), the privet (Legistrum vulgare), the Guelder rose ( Viburnum opulus), and the holly (Ilex aquifolium) possess acrid, irritant, nar- cotic properties even when eaten in small quantities. 1 Wharton and Stille : op. eit., vol. ii. p. 499. INDEX. A. Abdomen, enlargement of, 108 wounds of, GO Abortion, criminal, 116 feigned, 129 from natural causes, 128 means employed, 127 proofs of, 116, 124 Abortives, 128 Acetate of lead, 214 Acetic acid, 219 Aceto-arsenite of copper, 209 Acid, arsenic, 208, 209 arsenious, 200 carbolic, 219 hydrochloric, 193 hydrocyanic, 241 meconic, 224 nitric, 193 oxalic, 218 sulphuric, 193 tartaric, 219 Aconite, poisoning by, 240 Aconitia, 240 Aeon i turn napellus, 239 Adipocere, 33 vEthusa cynapium, 220 Affiliation, 144 After-birth, 121 Age deduced from teeth, 44 for legal responsibility, 148 Age of foetus, 121 of new-born child, 46 of skeleton, 47 Air, influence of, on putrefaction, 30 Alcohol, poisoning by, 227 Alkalies, poisoning by, 194 Amentia, 163 Ammonia, poisoning by, 194 Amorphous phosphorus, 197 Anaesthesia in rape, 103 Anaesthetics, poisoning by, 228 Analysis, chemical, 187 Animal food, noxious, 221 irritants, 221 Antagonism of poisons, 183 Antimony, poisoning by, 209 Apparent death, 25 Aqua fortis, 194 Areola of the breasts, 109 Arsenic, antiseptic power of, 203 poisoning by, 200 Arsenious oxide, 200 Arsenite of copper, 200, 209 Arsenites, 209 Arseniuretted hydrogen, 206 Artificial inflation of lungs, 132 Asphyxia, varieties of death by, 83 Asthenia, 36 Atropa belladonna, 235 Atropia, poisoning by, 235 Auscultation in pregnancy, 111 245 246 INDEX. B. Baby-farming, 92 Ballottement in pregnancy, 110 Balls, apertures made by, 58 Barium, salts of, 196 Bean, Calabar, 241 Belladonna, poisoning by, 235 Bestiality, 106 Birth, concealment of, 137 premature, 114, 116, 140 proofs of a live, 131 protracted, 114, 139 Bismuth, poisoning by, 217 Bitter almonds, oil of, 243 Bittersweet, poisoning by, 237 Bladder, rupture of, 60 Blisters from burns and scalds, 82 Blood, animal and human, 72 Blood, coagulation of, 78 Blood-corpuscles, human, 66 measurement of, 66 Blood-crystals, 74 Blood-stains, examination of, 62, 75 Blows, 60 Body, putrefaction of, 29 Bones, age of, 47 human and animal, 42 identification of, 42 Born alive, meaning of, 130, 140 Brain, injuries of, 60 Breasts, change of, in pregnancy, 109 Bromine, poisoning by, 199 Brucia, crystals of, 234 poisoning by, 235 Brunswick green, 209 Bullets, deflection of, 58 Buoyancy of the body, 88 Burns and scalds, 81 Butter of antimony, 211 c. Cadaveric alkaloids, 222 lividity, 29 rigidity, 27 spasm, 28 Cesarean section, 143 Calabar bean, 241 Caloricity, post-mortem, 27 Calvaria, 40 Cantharides, poisoning by, 222 Capacity, testamentary, 173 Carbolic acid, poisoning by, 219 Carbon dioxide, poisoning by, 230 monoxide, poisoning by, 230 Castor-oil beans, poisoning by, 221 Catamenia, suppression of, 108 Certificates of insanity, 172 Cervix uteri, 126 Cheese, poisoning by, 223 Chemical analysis, 187 Cherry-laurel water, 243 Chest, examination of, in cases of infanticide, 132 wounds of, 60 Child-murder, 130-138 Ch loral hydrate, poisoning by, 229 Chloride of antimony, 211 Chloroform, poisoning by, 229 Cholera mistaken for poisoning, 185 Chorion, 117 villous processes of, 120 Chromium, poisoning by, 217 Cicatrices, indentification by, 151 Cicuta virosa, 221 Circulation, cessation of, 24 foetal, 134 Circumstantial evidence in cases of poisoning, 189 Civil responsibility, 161, 171 Clothing, stabs in, 53 INDEX. 247 Clothing, stains of, 02 I loagulation of the blood, 78 ( locculus indicus, 244 Colchieum, poisoning by, 221 Cold, death from, 93 Coldness of the body in death, 26 Colic, painter's, 215 Coma, death by, 35 Compensation of medical witnesses, 20 Concealment of birth, 137 of habits in life insurance, 156 of pregnancy, 107 Conception, date of, 113 Concussion of brain, 60 Conia, 239 Conium maculatum, 239 Contracts to cure, 157 Contused wounds, 55 Contusions on the living and the dead, 55 Cooling of body after death, 26 Copper, poisoning by, 216 Cord, mark of, in hanging, 84 in strangulation, 84 umbilical, in foetus, 122 Coroner, office of, 23 Coroner's inquest, 21 physician, 19 Corpus luteum, 112 Corrosive sublimate, 211 Cotton, fibres of, 53 Courtesy, tenancy by, 143 Cowbane, poisoning by, 221 Cranium, fractures of, 60 Crimes, unnatural, 106 Criminal abortion, 116 responsibility, 161, 172, 175 Cross-examination, 49 Croton oil, poisoning by, 220 Crying, evidences from, 140 Cry psorch ides, 141 Cyanides, poisoning by, 242 ( lytisus laburnum, 244 I>. Date of conception, 113 Dead body, examination of, 24 Death certificate, 21, 24 phenomena and signs of, 24 presumption of, 149 varieties of, 35 Decidua vera, reflexa, and serotina, 119, 120 Declarations, dying, 50 Deformities, identification by, 48, 151 Delivery, concealed, 137 premature, 140 signs of, 136 Delusions, 176 Dementia, 170 Development of foetus, 116-121 of generative organs, 146 De ventre inspiciendo, 107 Diaphragm, position of, 132 Digitaline, 243 Digitalis, poisoning by, 243 purpurea, 243 Dipsomania, 167 Discharge of lunatics, 173 Disease, influence of, in poisoning, 1S4 Diseased flesh. 221 Distance at which persons can be seen, 151 Divorce, legal grounds for, 142 Docimasia circulations, 134 pulmonum, 132 Doubtful sex, 145, 147 Dress, examination of the. 53, 151 Dropwort, poisoning by, 221 248 INDEX. Drowning, death from, 87 resuscitation from, 89 signs of, 87 Drunkards, responsibility of, 167, 176 Ductus arteriosus, 134 venosus, 135 Dulcamara, poisoning by, 237 Dying declarations, 50 E. Eccentricity not insanity, 173 Eczema from arsenic-poisoning, 201 Effusion of blood, 55 Elaterium, 220 Embryo, human, 116 changes undergone by, 121 development of, 116 Emerald green, poisoning by, 209 Emetic, tartar, poisoning by, 209 Emphysema of the lungs, 133 Epilepsy, feigned, 154 Epispadias, 141 Ergot, 128, 220 Erysipelas, 60 Eserine, 241 Essence of mirbane, 243 Ether, poisoning by, 228 Evidence, medical, 49 of poisoning, 186 Examination, cross-, 49 in chief, 49 of blood-stains, 62 of clothes, 53 of hairs, 53 of lunatics, 172 of weapons, 53 of wounds, 52 Experts, medical, 18 Exposure, death from, 137 Extra-uterine conception, 129 F. Face, wounds of, 60 Family likeness, evidence from, 151 Farinaceous substances in stomach of infant, 136 Fatality in wounds, 51 Features, evidence from, 151 Fees, medical, 19, 20 Feigned abortion, 129 bodily diseases, 153 deafness and dumbness, 154 insanity, 177 wounds, 154 Fish, diseased, 223 Flax, fibres of, 53 Flesh, diseased, 221 Foetal circulation, 134 sounds, 111 vessels, changes in, at birth, 134 Foeticide, 116 determination of, 125 means of producing, 127 Foetus, development of, 116 Food, poisonous, 221 Fool's parsley, poisoning by, 220 Foramen ovale, 134 Forensic medicine, 17 Fowler's solution, 200, 209 Foxglove, poisoning by, 243 Fractures, identity from, 48 in new-born children, 137 Frigidity of constitution, 143 Fungi, poisonous, 221 G. Gases, noxious, poisoning by, 196 Gestation, normal period, 113 premature, 114 protracted, 113, 139 Gonorrhoea in rape, 100 INDEX. 249 Grand jury, 48 Gratuitous practice, 161 Guaiacum test, 63 Guelder rose, poisoning by, 244 Gunpowder, wounds from, 58 Gunshot wounds, 57 H. Habit, influence of, in poisoning, 184 Habits, concealment of, 156 Hrematin, 62 Hsemoglobin, 62 Hairs, identification of, 53 Hallucinations, 176 Hanging, death by, 85 signs of death by, 86 Head, wounds of, 60 Heart, wounds of, 60 Heat, cause of death by, 93 loss of, after death, 26 Hellebore, poisoning by, 221 Hemlock, poisoning by, 239 Hemorrhage of navel, 137 Henbane, poisoning by, 237 Heredity in insanity, 174 Hermaphrodites, 145 Hibernation, 25 Holly, poisoning by, 244 Homicidal mania, 168 wounds, 56 Human bones, 43 hairs, 52 Hydatids, uterine, 124 Hydrate of chloral, 229 Hydrochloric acid, 193 Hydrocyanic acid, 241 Hydrostatic test, 132 Hymen, evidence from, 99, 105 Hyoscyamus, poisoning by, 237 Hypnotism, relation of,to crime, 154 I. Identification of the dead, 42 of the living, 150 Idiocy, 163 Idiosyncrasy in poisoning, 181 Illusions, 176 Imbecility, 163 Impotence, 141 Impregnation, unconscious, 103 Imputed wounds, 153 Incised wounds, 54 Indian tobacco, 238 Infant born dead, proofs of, 131 Infanticide, 130 means of committing, 137 proofs of live birth, 131 Infantile leucorrhcea, 100 Inflation of lungs, 132 Inheritance, 139 Inquests, coroners', 21 medical witnesses at, 48 Insanity, 162 feigned, 177 in relation to life insurance, 157 medico-legal relations, 162, 171 puerperal, 169 varieties of, 162 Insensibility of eyes to light after death, 26 Inspection of the body, 38 Insurance, life, 155 Intellectual mania, 166 Intemperance in relation to life in- surance, 155 Interments, premature, 24 Intestines, wounds of, 60 Intoxication distinguished from concussion, 60 Iodine, poisoning by, 199 Irritant poisons, 191, 192 250 INDEX. J. Jessamine, 221 Juniperus sabina, 221 Jury of matrons, 107 K. Kiesteine in the urine, 110 Kleptomania, 166 L. Labor, premature, 116 Laburnum, 244 Lacerated wounds, 54 Laudanum, 225 Lead, poisoning by, 214 Legal medicine, 17 Legitimacy, 139 Leucorrhcea, infantile, 100 License of counsel, 49 Life insurance, 155 Lightning, death from, 95 Likeness, parental, 144 Linen, microscopic appearance, 53 Live birth, 130 proofs of, 132 Liver, wounds of, 60 Lividity, cadaveric, 29 Lobelia inflata, 238 Lobelina, 237 Lochia, 137 Lucid intervals, 176 Lungs, emphysema of, 133 examination of, in new-born children, 132 wounds of, 60 M. Majority, 148 Malpractice, 157 Mania, 164 Mania, feigned, 179 homicidal, 168 intellectual, 166 moral, 166 puerperal, 169 suicidal, 168 Marks of blood, 39, 62 Marsh's test, 206 Maternity, early, 114 Matrons, jury of, 107 Measurement of blood-corpuscles, 66 Meconic acid, 224 Medical evidence, 49 experts, 18 jurisprudence, 17 malpractice, 157 profession and the coroner, rela- tions of, 20 registration, 160 responsibility, 158 Medico-legal terms defined, 176 Melancholia, 165 Membrana pupillaris, 122 Menstrual blood, 79 Menstruation, 108 Mercuric chloride, 211 Mercury, poisoning by, 211 Micrometer, 66 Microscopic examination of blood- stains, 64 in rape, 101 Milk in stomach of infant, 136 Mineral acids, poisoning by, 192 Miscarriage, 116 Moles, identification by, 151 uterine, 123 Monkshood, poisoning by, 240 Monomania, 168 Monsters, 143 Moral mania, 166 INDEX. 25 1 Morphia, 224 Mortality of wounds, 58 Mother, examination of, 124, 13G Motives for crime, 168, 189 Miico-purulent discharges, 100 Muriatic acid, 193 Mushrooms, poisoning by, 221 Mussels, poisoning by, 223 Mutilated bodies, identification of, 42 N. Nrevi, identification by, 151 Neurotic poisons, 192, 223 Nicotina, 238 Nitre, death from, 196 Nitric acid, 194 Notes of autopsy, 38 Nux vomica, poisoning by, 231 Nymphomania, 165 O. (Enanthe crocata, 221 Oil of bitter almonds, 243 of savin, 128, 221 of tansy, 128 Opium, poisoning by, 224 Organs of adults, weights of, 41 Orpiment, 200 Osmosis of poisons after death, 187 Ossification-test of age in new-born child, 45, 115 Ovum, human, 140 Oxalic acid, 218 P. Prederastia, 106 Painter's colic, 215 Pallor of body after death, 26 Palsy from lead, 215 Papaver somniferum, 224 Paper-hangings, arsenic in, 209 Paralysis, feigned, 154 Paralytic dementia, 170 Parental likeness, 144 Paresis of insane, 170 Paris green, 209 Paternity, 144 Personal identity, 42, 150 Phosphorus, poisoning by, 197 Placenta, 118, 121 Plea of pregnancy, 107 Poisoned flesh, 222 Poisonous food, 222 Poisons, absorption of, 182 definition, 181 elimination of, 182 evidences of, 184 examination for, 185 mode of action, 182 post-mortem imbibition of, 187 Policy, life-insurance, 155 Post-mortem examination, 38 Potassium oxalate, poisoning by, 218 salts, poisoning by, 194 Pregnancy, 107 concealed, 107 duration of, 113 feigned, 107 in the dead, 115 precocious, 114 signs of, 107 unconscious, 115 Premature burials, 24 labor, 116 Presumption of death, 149 Privet, poisoning by, 244 Procreative power, 142 Protracted gestation, 113, 139 Prussic acid, 242 Ptomaines, 222 252 INDEX. Puberty, 141 Puerperal mania, 169 Punctured wounds, 54 Purulent discharges, 99 Putrefaction, 29 conditions modifying, 26 order of, 32 Putrescent food, 222 Pyromania, 167 Q. Quickening, 109 K. Rape, anaesthesia in, 104 definition, 97 on adults, 97, 103 on children, 97 on the dead, 105 on the insane, 97 Red phosphorus, 197 Re-examination, 49 Reinsch's test, 208 Respiration, 131 a sign of life, 134 cessation of, 24 Responsibility, civil and criminal, 171 medical, 158 Rigidity, cadaveric, 27 Rigor mortis, 27 S. Saccharine substance in stomach of infant, 136 Salivation, mercurial, 212, 214 Salt of lemons, 218 of sorrel, 218 Saturnine poisoning, 215 Satyriasis, 165 Sausage, poisoning by, 222 Savin, oil of, 128 Scalds and burns, 81 Scalp, wounds of, 60 Scars, identification by, 151 Scheele's green, 200, 209 Schweinfurt's green, 209 Self-inflicted wounds, 55 Seminal stains, 101 Sex, determination of, 147 doubtful, 145, 147 Sexual malformation, 141 Shock, death from, 59 Shot, wounds made by, 57 Signs of deatl), 24 Silk, microscopic appearance, 54 Skeletons, age of, 44 date of interment, 48 identification from, 48 sex of, 44 stature of, 48 Skull, identification from, 43 Sleep, influence of, in poisoning, 184 Smothering, death by, 83 Soda and its salts, 194 Sodomy, 106 Softening of stomach in poisoning, 186 Solanum dulcamara, 237 Somnambulism, 168 Sorrel, salt of, 218 Sound, velocity of, 151 Specific gravity of lungs, 132 Spectral analysis, 75 Spermatozoa, 101 Spine, concussion of, GO Starch, detection of, in stomach of infant, 136 Starvation, death by, 92 Sterility, 142 Still-births, 131 INDEX. 25.' Stomach, mode of examination of 186 redness of, in poisoning, 186 ulceration of, 180 wounds of, 60 Stramonium, poisoning by, 237 Strangulation, death by, 84 signs of, 84 Strychnia, crystals of, 234 Strychnine, poisoning by, 231 Sublimate, corrosive, 211 Subnitrale of bismuth, 217 Subpoenas, 18, 23 Sudden death, 20 Suffocation, death by, 83 of new-born children, 83 Sugar, detection of, in stomach of infant, 136 Suggillation, 29 Suicidal mania, 168 wounds, 55 Sulphide of arsenic, 200 Sulphuric acid, 193 Sunstroke, 93 Su perforation, 145 Surgical operations, death from, 60 Survivorship, 140, 149 Syncope, 35 T. Tartar emetic, 209 Tartaric acid, 219 Tattoo marks, identification by, 151 Teeth a test for age, 44 Tenancy by courtesy, 143 Testamentary capacity, 173 Tetanus from wounds, 59 Time elapsing since death, 33 Tin, poisoning by, 21S Tobacco, poisoning by, 237 Toxicology, 180 Trichina spiralis, 223 Trichinosis, 222 Trichomonas vaginalis, 101 U. Ulceration and corrosion in poison- ing, 186 Umbilical cord, condition of, in live and dead-born children, 135 insertion of, 122 Unconscious pregnancy, 115 Unnatural crimes, 106 Uterine sounds, 111 Uterus, changes of, in pregnancy, 108, 110, 126 normal unimpregnated, 125 putrefaction of, 115 V. Vagina, dilatation of, in rape of children, 99 wounds of, 125 Vaginitis, 104 Vegetable irritants, 218 Ventre de inspiciendo, 107 Veratrum viride, poisoning by, 221 Verdigris, 216 Vertebra?, fractures of, 86 Viability of the child, 116, 140 Vienna green, 209 Virginity, signs of, 99, 105 Voice, identification by, 151 Vulval penetration, 97 W. Wadding, wounds by, 58 Wall-papers, arsenical, 209 Water, influence of, on putrefaction. 29 Weapons, connection of, with wounds, 52 254 INDEX. Wedlock, born in, 142, 143 Weight of new-born child, 122 White hellebore, 221 lead, poisoning by, 215 Wills, capacity for making, 173 Witnesses, ordinary and medical, 17, 18 Wounds, cause of death by, 58 definition of, 51 from gunpowder, 57 made before and after death, 55 Wounds on different parts of body, 60 on new-born children, 138 self-inflicted, 55 variety of, 55 Y. Yellow arsenic, 200 Yew, poisoning by, 244 Z. Zinc, poisoning by, 217 Catalogue the Medical Publications W. B. SAUNDERS & COMPANY PHILADELPHIA ** j* j* Jt j* LONDON 925 Walnut Street Jt Jt <£ £ jt 161 Strand, W. C. Arranged Alphabetically and Classified under Subjects See page 18 for a List of Contents classified according to subjects THK books advertised in this Catalogue as being sold by subscription are usually to be obtained from travelling solicitors, but they will be sent direct from the office of pub- lication (charges of shipment prepaid) upon receipt of the prices given. 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Just Issued VOLUME II Editor, Sir J. W. Moore, B. A., M. D., F.R.C.P.L, of Dublin Professor of Practice of Medicine, Royal College of Surgeons in Ireland CONTENTS Erysipelas and Erysipeloid. By Dr. H. Lenhaktz, of Hamburg. Cholera Asi- atica and Cholera Nostras By Dr. K. von Lieuermeister, of Tubingen, Whooping Cough and Hay Fever. By Dr. G. Sticker, of Giessen. Varicella. By Dr. Th. von Jurgensen, of Tubingen. Variola (including Vaccination). By Dr. H. Immermann, of Basle. Handsome octavo volume of over 700 pages. Just Issued VOLUME VII Editor, John H. Musser, M. D. Professor oj Clinical Medicine, Univet 0/ Pennsylvania CONTENTS Diseases of the Bronchi. By Dr. I. A Hoffmann, of Leipsic. Diseases of the Heura. By Du. RoSENBACH, ■>! Berlin. Pneumonia. By Du. E. AuFKBCHT, oi Magdeburg. VOLUME VIII Editor, Charles G. Stockton, M. D. Professor of Medicine, University of Buffalo CONTENTS Diseases of the Stomach. By Du. F. RlEGEL, of Giessen. VOLUME IX Editor, Frederick A. Packard, M. D. 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Cohen and Eshner— Essentials of Diag- nosis, 1 5 Corwin — Physical Diagnosis, 5 Vierordt— Medical Diagnosis, 14 DICTIONARIES. The American Illustrated Medical Dictionary, 3 The American Pocket Medical Dic- tionary, EYE, EAR, NOSE, AND THROAT. An American Text-Book of Diseases of the Eye, Ear, Nose, and Throat, . . 1 De Schweinitz — Diseases of the Eye, . 6 Friedrich and Curtis— Rhinology, Lar- yngology, and Otology, 6 Gleason — Essentials of the Ear, .... 15 Gleason — Essentials of Nose and Throat, 15 Gradle — Ear, Nose, and Throat, .... 22 Grunwald and Grayson — Atlas of Dis- eases of the Larynx, 16 Haab and de Schweinitz— Atlas of Ex- ternal Diseases of the Eye, 16 Jackson — Manual of Diseases of the Eye, 8 Jackson — Essentials Diseases of Eye, . 15 Kyle — Diseases of the Nose and Throat, 9 GENITO-URINARY. An American Text-Book of Genito- urinary and Skin Diseases, 2 Hyde and Montgomery— Syphilis and the Venereal Diseases, 8 Martin — Essentials of Minor Surgery, Bandaging, and Venereal Diseases, . . 15 Mracek and Bangs — Atlas of Syphilis and the Venereal Diseases, 16 Saundby — Renal and Urinary Diseases, 11 Senn — Genito-Urinary Tuberculosis, . . 12 Vecki — Sexual Impotence, 14 GYNECOLOGY. American Text-Book of Gynecology, . Cragin — Essentials of Gynecology, . . . Garrigues — Diseases of Women, . . . . Long — Syllabus of Gynecology, . . . . Penrose — Diseases of Women, Pryor— Pelvic Inflammations, Schaeffer and Norris— Atlas of Gyne- cology, 17 Morton— Nurses' Dictionary, 10 HYGIENE. Abbott — Hygiene of Transmissible Dis- eases, 3 Bergey — Principles of Hygiene, .... 22 Pyle — Personal Hygiene, n MATERIA MEDICA, PHARMA- COLOGY, and THERAPEUTICS. An American Text-Book of Applied Therapeutics 1 Butler — Text-Book of Materia Medica, Therapeutics, and Pharmacology, . . 4 Morris — Ess. of M. M. and Therapeutics, 15 Saunders' Pocket Medical Formulary, . 11 Sayre — Essentials of Pharmacy, .... 15 Sollmann — Text-Book of Pharmacology, 22 Stevens — Modern Therapeutics, .... 13 Stoney— Materia Medica for Nurses, . . 13 Thornton — Prescription-Writing, ... 13 MEDIC A L P U/i /. ICA TIONS MEDICAL JURISPRUDENCE AND TOXICOLOGY. Chapman — Medical Jurisprudence and Toxicology 5 Golebiewski and Bailey— Atlas of Dis- eases Caused by Accidents 17 Hofmann and Peterson— Atlas of Legal Medicine, 16 NERVOUS AND MENTAL DIS- EASES, ETC. Brower — Manual of Insanity 22 Chapin — Compendium of Insanity, . . . 5 Church and Peterson — Nervous and 5 Mental Diseases, 5 Jakob and Fisher — Atlas of Nervous System, 17 Shaw — Essentials of Nervous Diseases and Insanity, 15 NURSING. Davis — Obstetric and Gynecologic Nurs- ing, Griffith— The Care of the Baby, . . Hart — Diet in Sickness and in Health, Meigs — Feeding in Early Infancy, . Morten — Nurses' Dictionary, . . . Stoney — Materia Medica for Nurses, Stoney — Practical Points in Nursing, Stoney — Surgical Technic for Nurses, Watson — Handbook for Nurses, . . . J 7 OBSTETRICS. An American Text-Book of Obstetrics, Ashton — Essentials of Obstetrics, . Boisliniere— Obstetric Accidents, Dorland — Modern Obstetrics, , . Hirst — Text-Book of Obstetrics, . Norris — Syllabus of Obstetrics, . . Schaeffer and Edgar — Atlas of Obstet rical Diagnosis and Treatment, . . . PATHOLOGY. An American Text-Book of Pathology. 2 Durck and Hektoen— Atlas of Patho- logic Histology 16 Kalteyer — Essentials of Pathology, . . 15 Mallory and Wright— Pathological Technique, 9 Senn — Pathology, and Surgical Treat- ment of Tumors, 12 Stengel — Text-Book of Pathology, ... 12 Warren— Surgical Pathology, 14 PHYSIOLOGY. American Text-Book of Physiology, . 2 Budgett — Essentials of Physiology, . . 15 Raymond — Text-Book of Physiology, . 11 Stewart — Manual of Physiology, . . 13 PRACTICE OF MEDICINE. An American Year-Book of Medicine and Surgery 3 Anders — Practice of Medicine, 4 Eichhorst — Practice of Medicine, ... 6 Lockwood — Practice of Medicine, . . . 9 Morris — Ess. of Practice of Medicine, . 15 Salinger & Kalteyer — Mod. Medicine, ti Stevens — Practice of Medicine 13 SKIN AND VENEREAL. An American Text-Book of Genito- urinary and Skin Diseases 2 Hyde and Montgomery —Syphilis and the Venereal I liseases, 8 Martin— Essentials ol Minor Surgery, Bandaging, and Venereal Diseases, . . 15 Mracek and Stelwagon— Atlas of Dis- eases of the Skin, i>, Stelwagon— Essentials of Diseases of the Skin, 15 SURGERY. An American Text-Book of Surgery, 2 An American Year-Book of Medicine and Surgery, 3 Beck — Fractures, 4 Beck — Manual of Surgical Asepsis, ... 4 Da Costa — Manual of Surgery, 5 International Text-Book of Surgery, . 8 Keen— Operation Blank, 8 Keen — The Surgical Complications and Sequels of Typhoid Fever 8 Macdonald — Surgical Diagnosis and Treatment, 9 Martin — Essentials of Minor Surgery, Bandaging, and Venereal Diseases, . . 15 Martin — Essentials of Surgery, 15 Moore — Orthopedic Surgery, 10 Nancrede — Principles of Surgery, . . . 10 Pye — Bandaging and Surgical Dressing, n Scudder — Treatment of Fractures, ... 12 Senn — Genito-Urinary Tuberculosis, . . 12 Senn — Practical Surgery, 12 Senn — Syllabus of Surgery, 12 Senn — Pathology and Surgical Treat- ment of Tumors ... 12 Warren — Surgical Pathology and Ther- apeutics, 14 Zuckerkandl and Da Costa — Atlas of Operative Surgery, 16 URINE AND URINARY DISEASES. Ogden — Clinical Examination of the Urine, 10 Saundby — Renal and Urinary Diseases, n Wolf — Handbook of Urine Examination, 22 Wolff — Examination of Urine, 15 MISCELLANEOUS. Abbott — Hygiene of Transmissible Dis- eases, 3 Bastin — Laboratory Exercises in Bot- any 4 Golebiewski and Bailey— Atlas of Dis- eases Caused by Accidents, . . . . 17 Gould and Pyle — Anomalies and Curi- osities of Medicine 7 Grafstrom — Massage, 7 Keating — Examination for Life Insur- ance, S Pyle— A Manual of Personal Hygiene, . 11 Saunders' Medical Hand-Atlases, . 16, 17 Saunders' Pocket Medical Formulary, . n Saunders' Question-Compends, . . 14. 15 Stewart and Lawrence — Essentials of Medical Electricity, 15 Thornton — Dose-Book and Manual of Prescription-Writing 13 Van Valzah and Nisbet — Diseases of the Stomach, 13 THE LATEST BOOKS. Bergey's Principles of Hygiene. The Principles of Hygiene : A Practical Manual for Students, Physicians, and Health Officers. By D. H. Bergey, A.M., M. D., First Assistant, Laboratory of Hygiene, University of Pennsyl- vania. Handsome octavo volume of about 500 pages, illus- trated. Brower's Manual of Insanity. A Practical Manual of Insanity. By Daniel R. Brower, M.D., Professor of Nervous and Mental Diseases, Rush Medical Col- lege, Chicago. i2mo volume of 425 pages, illustrated. Gorham's Bacteriology. A Laboratory Course in Bacteriology. By F. P. Gorham, M. A., Assistant Professor in Biology, Brown University. i2mo volume of about 160 pages, fully illustrated. Gradle on the Nose, Throat, and Ear. Diseases of the Nose, Throat, and Ear. By Henry Gradle, M. D., Professor of Ophthalmology and Otology, Northwestern University Medical School, Chicago. Handsome octavo volume of 800 pages, profusely illustrated. Sollmann's Pharmacology. A Text-Book of Pharmacology. By Torald Sollmann, M. D., Lecturer on Pharmacology, Western Reserve University, Cleve- land, Ohio. Royal octavo volume of about 700 pages. Wolf's Examination of Urine. A Handbook of Physiologic Chemistry and Urine Examination. By Charles G. L. Wolf, M. D., Instructor in Physiologic Chem- istry, Cornell University Medical College, nmo volume of about 160 pages. 22 DATE DUE • •**••• tot.. RIES " at the rowing, MAR 2 1997 APR 1 i 997 fe»A*«>^ p i^7 I /^> cial ar- At(^#<~«J t^C *, Tt \11^ rE DUE - j 1 Printed in USA C |»liffilftlHffi RS,TY L| BRARIES 0043058051 RA1051 Chapman C36 1896 m m mm SSntM KeSHS iUnSHraMM m ms wm m a vmm