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NOSE, THROAT AND EAR. Illustrated. P. BLAKISTON'S SONS 6 CO., PHILADELPHIA ?QUIZ COMPKNDS? No. 13 A COMPEND OF DENTAL PATHOLOGY AND DENTAL MEDICINE CONTAINING THE MOST NOTEWORTHY POINTS UPON THE SUBJECTS OF INTEREST TO THE DENTAL STUDENT AND A SECTION ON EMERGENCIES BY GEO. W. WARREN, A.M., D.D.S. PROFESSOR OF PRINCIPLES AND PRACTICE OF OPERATIVE DENTISTRY, PENNSYLVANIA COLLEGE OF DENTAL SURGERY, PHILADELPHIA FOURTH EDITION. ILLUSTRATED PHILADELPHIA P. BLAKISTON'S SON & CO No. 1012 Walnut Street 1903 FEB^ 8 1947 ut^'^^fL/'CuG^G^ Copyright, 1903, by P. Bi^akiston's Son & Co. Prkss of Rkpokt Publishing CoMPAiSv Lebanon, Pa. iil 'St cr> TO MV FRIEND PROFESSOR C. N. PEIRCE, D.D.S. NOTE. One of the first, and sometimes most difficult, les- sons the student has to learn is how to study, and many of our text-books are so voluminous that they prove a source of embarrassment to one just begin- ning his professional studies. Compends are de- signed to facilitate these labors, and if properly used as aids to more elaborate works, they have a special value. The author hopes that it will be found useful to students as a guide and help in giving a systematic view of the subject to be studied in larger works and as a book for review giving a thorough outline of work which has been done. CONTENTS. PAGE Anatomical and Physiological iNTuoDrcTiox ^ Development of the Teeth, ^ Structure of the Teeth 14 Anatomy of the Teeth !•' Decalcification of the Temporarj^ Teeth '^^ Dental Pathology and Therapeutics ^'-^ Inflammation, ; ^^ Diseases of the Dental Pulp and Membrane, ^^ Diseases of the Hard Dental Structure, 4*.> Injuries and Diseases of the :Maxillary P.ones 57 Defects of the Palatine Organs ^5 Extraction of Teeth, ^'^^ Deposits upon the Teeth, "^ Dental Medicine, ^4 Narcotics and Hypnotics ^4 Analgesics or Anodynes, *^ Anesthetics, '•' Stimulants, -^^ Tonics, 1^^ Sedatives, H-^ Antipyretics, H**^ Irritants 120 Astringents, 123 Styptics and Hemostatics, 126 Escharotics or Caustics, 12'i' Antizymotics (Antiseptics and Disinfectants), 131 Cathartics, 143 Emergencies, . 14^ Weights and Measures, ' l'if^2 Index, l'*^^ vii ABBREVIATIONS. ABBREVIATION. LATIN. aa Ana (G.), Ad saturand., . . .Ad saturandum, . Ad lib., .... Ad libitum, Aq., . . . . ^ Aqua, .... Aq. dest., .... Aqua destillata, . Comp., Compositus, Ext., Extractum, . F. or Ft., . . . .Fiat vel flant, Garg., Gargarysma, . Gr., Granum, vel giana, Gtt Gutta, vel gutt^, . Infus., Infusum, . M., Misce Mist Mistura, . . . 0-. Octarius, Pil Pilula, vel pilulae, Pulv., Pulvis, vel pulveres, Q- s., Quantum sufficit, IJv Recipe, S., Signa, .... Spts., Spiritus, ss., Semis, .... Syi., Syrupus. Tinct., Tinctura, . It) Libra *. Uncia, .... 3» Drachma, . 9. Scrupulus, iE Fluid uncia, f3, Fluid drachma, T(\^, , , . , . . Minim, ENGLISH. . Of each. . Until saturated. . At pleasure. . Water. . Distilled water. . Compound. . An extract. . Let there be made. . A gargle. . A grain, or grains. . A drop, or drops. An infusion. . Mix. . A Mixture. . A pint. . A pill, or pills. A powder, or powders. . A sufficient quantity. . Take. . Write directions. . Spirits. . The half. . Syrup. . A tincture. . A pound. . An ounce. . A drachm. . A scruple. . A fluid ounce. . A fluid drachm. . A drop. Vlll DENTAL PATHOLOGY AND DENTAL MEDICINE. ANATOMICAL AND PHYSIOLOGICAL INTRODUCTION. DEVELOPMENT OE THE TEETH. A Tooth. — It is sometimes difficult to give in a few words a satisfactory definition to a term. This it seems has been the case with the word tooth. Some writers say "a tooth is a hard substance situated in the anterior portion of the alimentary canal;" others define it as "a papilla of the raucous membrane of the gum, which has undergone a characteristic development." Again it is described "a bony structure implanted in the alveoli along the margins of the jaw." Broomell, in his excellent work on Dental Anatomy and Histology, says "a tooth is a specialized organ for the seizure and mastication of food, placed at the entrance of the alimentary canal." But as a little fuller and more satisfactory explanation of the term we might accept the following : "A tooth is a small organ, bony in character, which normally occupies an alveolar cavity of the upper or lower jew. Collectively the teeth are the hardest portion of the body and are the principal organs of mastication." The developmen^" of these organs is a most curious and interesting process, com- mencing very early in fetal life. The Enamel Organ. — During the seventh week of fetal life there appears on the border of the jaw a ridge of epithe- 9 10 DENTAL PATHOLOGY AND DENTAL MEDICINE. lium, known as the dental ridge; from this the epithelial folli- cles are deflected inward, and later on form what is known as the Enamel Organ. Each follicle represents an individual .a Fig. 1. Fig. 2. Figs. 1 and 2. — Theee Stages in Developing Enamel Organs. a. Dental ridge, c. Infant layer of cells, d. Epithelial cord. e. Stellate reticulum, f. Dentinal papilla, g. Inner tunic, h. Outer tunic, i. Transverse section of vessel. 7c. Forming bone. tooth. The cells active in the formation of the enamel are known as enamelblasts or amelloblasts.. The Dentine Organ. — A papilla arises in the dermal tissue, DEVELOPMENT OF THE TEETH. 11 at a point immediately in contact with the rounded portion of the enamel organ — ^that is, from below in the lower jaw, and from above in the upper Jaw. Simultaneously, the bottom of the enamel organ is rendered concave, in correspondence to the form and size of the dentine papilla, covering it like an in- verted cup : this dentine bulb begins to assume the form of the tooth from the ninth to the tenth week. (See Figs. 1 and 2.) By the end of the twelfth week the follicles of the first, or deciduous, set of teeth are completed. Fig. 3. a. Outer layer of mucous membrane. 6^ 6. Calcifying bone. c. Epithelial cord. d. Dentinal papilla, e. Calcifying enamel, f. Enamel germ. h. Permanent tooth germ. When the follicle is completed, it is developed by vascu- lar tissue, forming the dental sac; this is about the fourteenth week. During this process of dentification there appears in the jawbone a groove within which the dentinal follicles rest. Follicular Development of the Permanent Teeth. The follicles of the permanent teeth begin to develop about the seventeenth week of embryo life; of these, the first to become completed are those of the four first molars, at ahout the twentieth weeh; these are followed by the follicles of the teeth anterior to them, which are completed before birth. 12 DENTAL PATHOLOGY AND DENTAL MEDICINE. The ten anterior teeth originate from the necks of the primitive follicles, while the hud of the follicle of the first per- manent molar originates from the epithelial lamina, as do the deciduous teeth, and back of all the follicles of the temporary- set. The follicle of the second permanent molar originates from the neck of the follicle of the first molar, and begins to Tooth sac of Per- manent Tooth. Periosteum and Mucous Mem- brane from Hard Palate. Gubernaculum. Tooth sac for Per- manent First Molar. Fig. 4. — Tooth-sacs of Deciduous Teeth. form about the twelfth week after birth. This budding process is illustrated in Fig. 3. It is also very clearly shown in Fig. 4 which represents a dissection made by Prof. Broomell. The follicle of the third permanent molar begins to develop about the third year after birth, budding from the neck of the follicle of the second molar, and is in its follicular evo- lution about three years, thus loosening its connection with the epithelial band at about the sixth year. It is then from DEVELOPMENT OF THE TEETH. 13 twelve to fifteen yeai's coiuing- to such maturity as to emerge from the giim. Calcification. The Calcification of the Enamel. — The deposition of lime salts., which gives the teeth their characteristic hardness and is termed calcification, commences at the surface of the dentine and proceeds outward, each enamel rod taking the form of the cell, which in their compactness take on various shapes, usually, however, hexagonal, and the lime salts from each are depos- ited in close contact with each contiguous cell; there being but a very small amount of animal matter, the cement material be- tween them. When it is completed the enamel organ disappears and nourishment to the enamel can only be had through the surface lying nearest to the dentine, which is accomplished through osmotic action. The calcification of the dentine commences on the surface next to the enamel organ, and progresses from without inward, this being the point where mineralization begins in the tooth structure. The working cells of the dentine, the odontoblasts. throw out processes around which the lime salts are deposited, the processes leng-thening with the thickening of the cap of dentine; thus forming the tubular structure of dentine. The processes occupying the tubules of the dentine are simply pro- toplasmic prolongations. As age advances, both the tubuli and fibrilli decrease in size, and in old age the extremities are nearly or wholly obliterated. The Cementum. — The cells active in the formation of the Cementum are termed Cementohlasts. This structure is formed from the pericemental membrane, remaining as the residue of the dental sac, and becomes adherent to the previously calcified dentine. Calcification commences about the seventeenth week of fetal life, in the temporary incisors, and in the remaining temporary teeth during the seventh month; in the first permanent molars 14 DENTAL PATHOLOGY AND DENTAL MEDICINE. during the eighth month; during the first year in the perma- nent incisors and cuspids; the third year in the bicuspids, the fifth year in the second molars, and during the eighth year in the third molars. It requires about two years for calcification to become com- pleted in a deciduous tooth, and about ten years in a perma- ment tooth. The progress of calcification is shown in Fig. 5. STRUCTUEE OF THE TEETH. Physiologically, the teeth are divided into the enamel, den- tine, cementum, pulp, and pericemental membrane. The enamel covers the crown portion of the dentine. It is the hardest and most dense of all organic substances, hence it serves as a protection to the dentine from abrasion, and forms a greater resistance to mechanical force and the action of acids as well as to beautify the teeth. The dentine gives the typical form of the teeth. The chief characteristics which adapt it to constitute the main body of the tooth structure are its density and vitality. While it en- closes within it the pulp, it is itself enclosed on the crown by the enamel and on the root by the cementum. Frequently im- perfect dentine formations occur, known as interglobular spaces; these are found near the surface of the enamel and are due to malnutrition during the period of calcification. Pits in the enamel will very often be found accompanying these interglobular spaces, and are due to the same causes. The cementum, a somewhat dense substance, covers the root portion of the dentine. Its special use is, by being inter- mediate in the density of its structure, to form a union of the soft tissue of the root membrane with the dentine, thus aiding the pulp in nourishing the tooth, and preserving, in a measure, the vitality of the tooth after the pulp may have been de- vitalized. O) CO d o o o '■*-> c3 O U li U U o o o 3 3 P fi ja ?? e:?£? i) ID c4 9) 3_ a a/ aa 03 IB to <. 82 DENTAL PATHOLOGY AND DENTAL MEDICINE. Full anesthesia, profound, or surgical anesthesia as one may choose to term it, is marked by complete relaxation of the muscular system, and an absence of reflex irritability which is usually tested by touching the cornea or conjunctiva of the eye. With muscular relaxation full and regular respiration fol- lows, accompanied by stertor or snoring largely due to vibra- tions of the relaxed soft palate. The fourth or paralytic stage should always be guarded against. It is the danger ground and may result in paralysis of the heart or respiration. The principal general anesthetics are ether, chloroform, nitrous oxide gas, and bromide of ethyl. Local anesthetics are agents whose action is limited to the circumscribed parts to which they ar^ applied. They paralyze the nerves of the part, thus temporarily destroying sensation. They act similarly to the local anodynes, except that while the anodynes diminish the sensibility of the parts, the local anes- thetic destroys sensation entirely for a time. The principal agents of this class are cocaine, eucaine, ethyl chloride, and absolute ether. Ether^ C^HjqO. Derivation. — Sulphuric ether (improperly so called) is ethylic ether, or oxide of ethyl. It is obtained "by the distilla- tion of ethylic alcohol and sulphuric acid, the acid dehydrating the alcohol and remaining in the retort. (C^IIgO)^ — 11,0= C,H,„0. Medicinal Properties and Actions. — Ether is a colorless, volatile, and inflammable liquid. It is an anesthetic and ano- dyne, a diffusible stimulant, and a narcotic poison. Adminis- tered internally, it is one of the most powerful secretion stimu- lants known. The action of the heart, and hence the circulation is increased, flushing and warmth of the surface soon follow. The senses are tnore keen, and the phenomenon of alcoholic in- ANESTHETICS. 83 toxication results, which is less protracted, however, ether being quickly eliminated, chiefly by the lungs. The first effect of ether, that is the increase in arterial pres- sure due to heart and vaso-motor stimulation, is soon followed by a fall in blood pressure and lowering in force and frequency of the heart movements. Principal Preparations: — Ether Fortior, stronger ether, ethyl oxide, "C^H^^O," con- tains about six per cent, of alcohol. Sulphuric Ether, ethyl sulphate, C^H^^SO^. Nitrous Ether, ethyl nitrite (sweet spirit of nitre), C.,E[.!IsrO,. The well-known antipyretic and diaphoretic. Dose, TUv-3ij. Dental Use.— Ether is employed as a general and local anesthetic, as a local anodyne in neuralgia and odontalgia, and as a counter-irritant, evaporation being prevented. Ether as an Anesthetic Agent. — The practicability of producing anesthesia by the inhalation of ether was first demonstrated by Dr. Horace Wells, of Hartford, Conn., and Dr. W. G. S. Morton, of Boston, Mass., during the years 1844-'46. Ether, though less prompt in its action, is much safer than chloroform. It has its necrology, however ; a number of fatal cases (about thirty) have been reported. The Administration of Ether. — The operator should be well assured, before administering an anesthetic, that the pa- tient is not laboring under any serious disease of the heart, brain, or lungs, as ignorance in this direction might lead to fatal results. The clothing about the neck and chest should always be loose, lest it act as an impediment to respiration, and if artificial teeth be worn, they should be removed before the administration of the anesthetic. For the inhalation of ether and chloroform a number of instruments have been devised, but the simplest and probably 84 DENTAL PATHOLOGY AND DENTAL MEDICINE. the best method is from a sponge, napkin, or handkerchief, placed within a cone, formed of a towel or stiff paper, with a small opening at the apex for the admission of air; or a small piece of lint can be held in the palm of the hand and on these pour the anesthetic agent. The inhalation should be commenced cantionsly, the pa- tient should be directed to breathe quite naturally, and to obey any instructions given, as the rasing of the hand, etc. The towel or napkin should be held six inches from the patient's face, aproaching it gradually, thus overcoming the irritating effect and a sense of strangulation, which follow when the agent is placed at once to the mouth and nostrils. Action of Ether. — The first stage of anesthesia is stimulant, the second is tetanic or convulsive, the third, complete relax- ation. During complete anesthesia the face is cool, there being a profuse perspiration; the eyes are closed, insensible to the touch, and the pupils are somewhat contracted. The respiration and pulse are somewhat slower than normal, as shown in the following table : — Normal pulse, 72 a minute. Pulse on administration of ether: — 1st min. 2d min. 3d min. 4th min. 5th min. 92 109 110 94 69 Normal respiratory movements average about 20 a minute. Respiration on administration of ether: — 1st min. 2d min. 3d min. 4th min. 5th min. 23 24 26 18 15 Order in Which Nerve Centers Are Acted Upon.— First, the cerebrum; second, cerebellum; third, the spinal cord, fourth, the medulla oblongata. ANESTHETICS. 85 The Quantity o£ Ether Required. — Largest quantity, 9 ozs. ; minimum, 2^2 ozs. ; average quantity to produce anesthesia, 5 ozs. The Time Required for Full Anesthesia. — Longest time required, 24 minutes; shortest time, S^/^ minutes; average time, 8 minutes. The Dangers of Anesthesia. — There are conditions ren- dering general anesthesia dangerous, and the practitioner, whether medical or dental, should be well assured, before ad- ministering ether or chloroform, that none of these are present. They are fatty degeneration of the heart, valvular lesions, kid- ney disease, brain tumors, respiratory obstructions from en- larged tonsils, thoracic tumors or aneurism, and chronic alco- holism. It should be born in mind that ether is irritant to the air passages and kidneys, lessening the elimination power of the latter. An anesthetic should never be administered on a full stomach, as sickness would likely follow that would inter- fere with the operation, and anesthesia of the glottis prevents the expulsion of vomited matter in case it enters the larynx by regurgitation; neither should it be given after long fasting, as an absence of nutrition would tend toward cardiac paralysis; excitement should be avoided, instruments should be kept out of sight, and too many spectators should not be present. A painful operation should not be commenced before the stage of complete anesthesia is reached, or it may cause death from shock, as the result of peripheral irritation. Treatment of Dangerous Symptoms. — In case of the sus- pension of the heart's action, the agent should be withdrawn, the body placed in a reclining position, and, if need be, inverted, and air freely admitted. The failure of respiration requires the drawing forward of the tongue, by a finger being thrust deeply into the mouth; the inhalation of a good stimulant, nitrite of amyl, gtt. ij to gtt. v; but care is necessary in its use, and not jnore than two or three drops should be administered to patients 86 DENTAL PATHOLOGY AND DENTAL MEDICINE. who have never inhaled it. The inhalation of ammonia is pos- sibly as efficient, and can be used with more freedom than nitrite of amyl. Galvanism, too, has been successfully employed as a cardiac and respiratory stimulant, "the positive pole being; placed to the nostril and the negative pole over the diaphragm, to excite a reflex action between the fifth pair and the pneumo- gastric, or the poles may be applied directly over both phrenic nerves, or on a line with the fourth cervical vertebra, in order to stimulate respirations; or one pole may be placed over the upper dorsal spinous process and the other pole over the apex of the heart, to induce cardiac contraction."* And if necessary, artificial respiration should be employed (see Appendix) and warmth applied. The extremities should also be rubbed briskly, rubbing upward. Note. — It should be remembered that ether vapor is heavier than air, and forms therewith a highly explosive mixture. Therefore, if a light must be in the room, it should be high above the patient. A grate fire, gas stove, etc., in the vicinity are very dangerous. CHLOROFORM;, CHCI3. Derivation. — Chloroform (Ter-chloride of Methyl, or Meth- ylic Ether) is obtained by distilling alcohol with chlorinated lime. It was discovered in 1831, by Samuel Guthrie, of Sack- ett's Harbor, N. Y. The form for medicinal use is Chloroformum Purificatum, or Purified Chloroform. Medicinal Properties and Action. — When inhaled, chloro- form is an anesthetic, and when administered internally, it is an anodyne and antispasmodic. If swallowed undiluted, it excites great inflammation of the mucous membrane and causes violent gastritis. *Gorgas' "Dental Medicine." ANESTHETICS. 87 Its effects are similar to those of ether, but more rapidly produced, and it is more powerful in its action; hence requiring more care in its administration. When first administered (internally) it causes a feeling of warmth in the stomach, which is soon followed by a sense of coldness. It increases the action of the heart, producing excite- ment of the brain, followed by depression and deep, heavy sleep. In large doses it causes stupor and insensibility, and has caused death. Therapeutic Uses. — Chloroform is used for the same pur- poses as is ether, and is much employed locally in liniments. Administered by inhalation, it is a general anesthetic, and when administered internally, in substance, it is an anodyne and antispasmodic, and is used as such in cases of nausea, sea sickness, sick headache, and in cases of cholera. In the last named it has probably proven more efficacious than any other single remedy. Dose, nij-^ss, diluted, internally. Spirit of chloroform (chloroform, Bj; diluted alcohol, Sij), 3ss-3j. For inhalation, ^j-Bj. Average, 3iij. Dental Use. — Chloroform is employed by some in dental practice as a general anesthetic; its use, however, is growing less every year, in favor of ether and nitrous oxide gas. It is also used as a local anesthetic; in this case it is generally com- bined with other substances, as aconite, alcohol, ether, opium, etc. For administration as an anesthetic, treatment of dan- gerous symptoms, etc., see Ether. ® Chloroform Narcosis. — Shortest time, 2 minutes 30 seconds. Longest time, 14 " 30 " Average time, 6 "24 " Chloroform mortality is 1 in 3,000; over 500 fatal cases are reported, none of which, however, were in obstetrical prac- tice. The apparent safety of chloroform in obstetrics has been 88 DENTAL PATHOLOGY AND DENTAL MEDICINE. explained by the theory that death from chloroforra is due to vasomotor paralysis, and as pregnancy increases the vasomotor tension, pregnant women are in consequence less liable to fatal results. Compared with ether mortality, 1 in 16,000. The physiologic action of ether and chloroform compared is as follows : Organs, Tissues, etc., affected. Arterial tension ( and blood-pres- < sure, ( Heart, Lung-s, Mouth, ncse and pharynx, Stomach and in- r testines, I Liver, i Kidneys, Temperature, Pupils and corneal f reflex, ' Ether. Greatly increases both. Followed by fall. Stimulates and large doses paralyze. Zone between these quite large. Has slightl.v direct ir- ritating effect, caus- ing increased tracheo- bronchial secretion. Stimulates respiratory center and large doses paralyze. Zone very large. Greatl.T increases all se- cretions, f^arge doses paralyze muscles of tongue, epiglottis and palate. Both above favor aspiration. Considerable nausea and ^ vomiting. I No effect. In normal kidneys ] transitory effect | (casts and traces of albumin). decreased | amount of bio d and ) secretion. In diseased i kidneys has a bad ef- I feet, may cause anu- ! ria and uremia. J Lowers it. Pupils contracted some "] and respond. Corneal reflex of some value. Chloroform. Gradually decreases both. Depresses and large doses paralyze ; zone between these two, small. Slows respiration and large doses paralyze. Zone small. Scarcely any effect on se- cretions. Large doses also paralyze tongue, etc. Less nausea than ether; in large doses causes some fatty degeneration of muscles. Prolonged administration causes fatty degenera- tion with decreased gly- cogen, icterus, and in fatty liver may cause acute yellow atrophy. In ordinary administra- tion and normal kidneys but slight transitory ef- fect. In prolonged ad- ministration causes con- siderable fatt.v degen- eraiion. Lowers it less than ether. Pupils somewhat con- tracted but respond. Sec- ondary dilation of pupil, bad sign. Corneal re- flex of li**!* vnlnp. ANESTHETICS. 89 Nitrous Oxide Gas, NgO. History. — Nitrous Oxide, or "Laughing" Gas, was discovered by Dr. Priestly in 1776, and its respirability demonstrated by Sir Humphry Davy, though the results v^ere not published until some twenty years afterward. In 1844 Dr. Horace Wells prac- tically demonstrated the value of its anesthetic property for the relief of pain during surgical or dental operations. Nitrous oxide gas is manufactured by slowly melting and boiling the salt nitrate of ammonia in a glass retort, dissolving it into a vapor of water and a permanent gas (NH^NOg+Heat =N20+2H20). The gas should pass through three wash bottles, the first containing a solution of the sulphate of iron or caustic potash, and the other two pure water, for the purpose of purifying it before it enters the receiver, from which it is administered to the patient through an inhaling tube. A pound of the salt will generate about thirty gallons of the gas. It is perfectly fused at 226° F., white fumes are emitted at 302° F., and gas begins to evolve at 460° F. If the temperature is raised to 500° F., a dangerous impurity, nitric oxide, is given off; this need not be generated, however, if the proper care is observed, not allowing the temperature to rise above 480° F. Liquefied Nitrous Oxide. — The most convenient form for use is the liquefied gas, it being liquefied and solidified under intense cold and great pressure. It is then secured in strong iron cylinders, from which it is allowed to escape into an in- haling bag when needed for use. The advantages of this form of gas are its purity, con- venience for use, the large supply which can be kept on hand, and its comparative freedom from deterioration, notwithstand- ing its age. Properties and Actions. — ^Nitrous oxide gas is an elastic, colorless gas, with a very slight and agreeable odor. It will freeze into a beautiful, clear, crystalline solid, at about 15° F. below zero. 7 90 DENTAL PATHOLOGY AND DENTAL MEDICINE. "By the evaporation of this solid, a degree of cold may be produced far below that of carbonic acid bath in vacuo, or lower than 17° F."'^" Nitrous oxide gas supports combustion with nearly the same promptness as oxygen. As an Anesthetic. — Nitrous oxide gas is the most pleasant and the safest general anesthetic known. The shortness of the anesthetic stage is the greatest objection to its administration for surgical operations, though its rapid action, comparative safety, and the transient nature of its effects on the system render it the most useful anesthetic agent for all minor opera- tions, such as the extracting of teeth, removal of nerves from the teeth, where the tooth substance is lost to such an extent that a devitalizing agent could not be retained, for the lancing of abscesses, etc. The administration of nitrous oxide gas for dental oper- ations, should be conducted with the same care that is given to ether and chloroform, though it is a comparatively safe anesthetic. The patient should be seated in an operating chair which will admit of the back being lowered to such a degree that the patient could at once be placed in a horizontal position. The dress about the throat and waist, if tight, should be previ- ously loosened, and the patient should not have partaken of food for at least two hours previous to the inlialation of the gas. A mouth prop, of which there are several patterns manu- factured, should he placed between the teeth, to prevent the closure of the jaws, as the muscles become rigidly contracted during the administration of this gas. The most suitable prop is one made of India rubber — the ordinary lead-pencil eraser, cut in proper lengths, answers the purpose very nicely — or a firm cork, as it prevents injury to the teeth or fillings, which sometimes occurs when a mouth prop of a hard substance is *Gorgas' "Dental Medicine." AXESTHETICS. 91 used. The patient is then directed to take full, regular, and deep inspirations of the gas, the nose being held or covered, to prevent the admixture of atmospheric air. Its anesthetic effects are soon made manifest by strong, involuntary respira- tions, accompanied by snoring, this being caused by the relax- ation of the nuiscles of the pharynx, and paralysis of the tongue, causing it to fall back toward the throat, interfering with breathing, and a livid appearance of the lips, cheeks, and finger nails, due to the discolored blood in the capillaries. Bu1 the most delicate test for complete anesthesia is, as in ether and chloroform, the loss of sensibility to the touch in the conjunctiva of the eye. The amount of gas required to produce complete anesthesia varies, from five to fifteen gallons being the usual amount. Out of several administrations the writer has had one case where 65 gallons were required, and another where SO gallons were in- haled before the anesthetic stage was reached. The first stage under nitrous oxide gas is muscular activity. The second stage is muscular rigidity. It can not be con- tinued until complete muscular relaxation, lest the patient die of- asphyxia. Nitrous Oxide Gas Mortality. — There is about one death to each 125,000 administrations. Dangerous Symptoms, with Treatment, etc. — See Ether. Bromide of Ethyl^ C^H^Br. Derivation. — Bromide of ethyl, or hydrobromic ether, is obtained by distilling bromide of potassium and sulphuric ether, and redistilling with chloride of lime. Properties. — It is a colorless, volatile fluid, possessing an agreeable ethereal odor and a pungent taste. It is not inflam- mable, caustic, nor irritant; in this respect it is preferable to chloroform or ether as an anesthetic agent. The Administration. — Bromide of ethyl is administered as is ether or chloroform, or in a folded starched napkin, so as to 92 DENTAL PATHOLOGY AXD DENTAL MEDICINE. cover the face, as directed by Prof. Gorgas. A soft linen hand- kerchief is placed inside the napkin, and upon this the agent is poured; one drachm should be used at first, directing the pa- tient to take deep, full inspirations. At the end of two minutes the second drachm should be added; this should be repeated at intervals of two minutes, until complete anesthesia is produced. The quantity differs according to the susceptibility of the patient. Action. — The administration of bromide of ethyl is attended with some danger, and clinical experience has not demonstrated to careful operators that it is as safe as some other and older agents of this class. It has a toxic action on the centers of respiration. The heart force is decreased and its action is more frequent, which contributes to the paralysis of the respiratory centers. Several deaths occurred in a very limited number of administrations of this agent. Precautionary measures in administering anesthetics: That respiration may in no way be hampered, the operator should see to it that the respiratory tract is not encroached upon either by a collar at the throat, or by corset stays about the chest. It is quite as important to test the freedom of respira- tion before administering an anesthetic as it is to take the pulse or listen to the heart's action. Where enlarged tonsils are noted and post-nasal growths indicated or enlargement of the glands of the neck, goitre, severe bronchitis or any other local trouble which might interfere with respiration, or where there is apparent existence of serious disease of the vital organs, as indicated under the dangers of anesthesia, a general anesthetic should not be administered without consulting the family physi- cian, and possibly securing his co-operation. The neurotic patient may be at first misleading. Mental dis- quietude frequently causes an accelerated action of the heart, or such a patient may at first hold the breath or breathe ap- parently with much effort. These should be noted and not ac- cepted as normal conditions. ANESTHETICS. 93 Some operators prefer the admixture of ether and chloroform, or alcohol, ether and chloroform, while others adhere strictly to the separate drug; and claim that the various mixtures are to be depreciated owing to the uncertainty as to the exact propor- tion of the separate ingredients the patient would appropriate. Cocaine. Source. — Cocaine is the active crystalline alkaloid of Ery- throxylon coca, a small Peruvian shrub. The leaves resemble those of Chinese tea, and in South America thy are used by eight millions of people much as we use tea or coffee. In the preparation of the alkaloid, it is necessary that the leaves be carefully gathered, as the best quality only should be used. They should be dried, and not injured by age or exposure to the air, as moisture deprives them of value. Preparations of Erythroxylon : — Extractum Erythroxyli Fluidum, fluid extract of ery- throxylon. Dose, 3ss-ij. Salts of cocaine. Cocaine Hydrochlorate, C^_H2iN0^. — Dose internally, gr. Vg-ij ; most commonly used as a local anesthetic in aqueous so- lutions, 2-5 per cent. Cocaine Oleate, cocaine and oleic acid, 5-20 per cent, solu- tions for external use. Cocaine Hydrobromate, cocaine and hydrobromic acid, 2-10 per cent, as a local anesthetic. Cocaine Wines, Pastes, Lozenges, etc., are made in great varieties. Medicinal Properties and Action. — Cocaine, when applied locally, acts as an anesthetic ; when taken internally in small doses, it is a general stimulant, improving digestion, stimulating the respiration, circulation, etc. It produces wakefulness and a marked diminution of the sense of fatigue and hunger., ^ov 94 DENTAL PATHOLOGY AND DEKTAL MEDICINE. this reason the leaves are chewed by the Peruvian Indians to sustain them during long journeys or arduous labor. A toxic dose, or long-continued use (cocaine habit) pro- duces insomnia, decay of the moral and intellectual powers, hallucinations, insanity, and death. Dental Use. — The salts of cocaine have proven very efficient for their local anesthetic and anodyne effects; their power as a local anesthetic is very great over a limited area, and hence it is of special value to the dentist, for operations upon the sub- mucous tissues and the extraction of teeth, where it should be used by hypodermic injection, or applied to the gum on either side of the tooth to be extracted^ the latter method being the safer; two or three applications should be made at intervals of about two minutes each, when a painless operation is generally secured. It has been found to act very happily, also, in connec- tion with arsenious acid, for the devitalization of dental pulps, the pulp dying without giving the patient any discomfort. But as for its use as a pain obtundent in hypersensitive dentine, its practical benefits are questionable. A warning, however, should be given, that a potency for evil lurks in this most valuable drug. In many cases where it has been injected into the gum tissue for extraction of teeth, toxic results of an alarming nature have occurred and patients have been rendered ill for several weeks. This, however, is not apt to follow when the patient is of a sanguine temperament and in good health. The writer has made a record of many cases where toxic results have followed the use of this drug, and finds them all to be of a nervous or hysterical temperament, or preg- nant women. The lesson is that we should use judgment and discrimination in its application. Dangerous Symptoms. — The extremities usually become cold and rigid, the eyes staring and glassy, and the face pallid, while the pulse is weak, the heart beats faint, and respiration slow and weak — the symptoms of an impending collapse. ANESTHETICS. 95 Treatment of Dangerous Symptoms. — Fresh air should be admitted and some good stimulant administered, such as brandy, or aromatic ammonia and nitrate of amyl — ^by inhala- tion, or ether in case of convulsions, and if need be the battery. As soon as the patient is able, assist him to stand up and promenade. Chloride of Ethyl, C^HgCl. Properties. — Chloride of ethyl is a colorless liquid possessing a strong ethereal odor, and is very volatile and inflammable in ordinary temperature. Its boiling point is about 50° F. It is due to this low boiling or vaporizing point that it is so exactly adapted to the special requirements of a local anesthetic. It is put up in convenient glass tubes, drawn out to a fine point, and hermetically sealed. The point of the tube is marked by a file scratch at its smallest part. Hero the point is broken off when ready for use, either by the fingers or the forceps. Immediately the chloride in a gaseous state escapes from the small opening, and if the tube is partially inverted, a small jet of the liquid is projected; this is further accelerated by allowing a good portion of the tube to come in contact with the hand, the warmth of which hastens the vaporization of the liquid. The preparation of chloride of ethyl, as spoken of above (in glass tubes), is a patented process. As the chloride evaporates in ordinary temperature and is very inflammable, the point has to be drawn out and sealed while the tube and its contents are immersed in ice water. The Application and Action. — ^When about to apply, the parts to be anesthetized should be thoroughly dried, by means of absorbent cotton or napkin, then the point of the tube should be broken, or the screw-cap removed as the case may be, as pre- viously directed, and the fine jet of chloride directed upon the surface. 96 DENTAL PATHOLOGY AND DENTAL MEDICINE. If teeth are to be extracted, a napkin should be placed in the mouth back of the teeth to be operated upon, and the patient directed to breathe entirely through the nose; the liquid should then be projected upon the mucous membrane around the tooth or root and upon the cheek over the track of the inferior maxil- lary nerve for the lower, and on the temple over the emergence of the fifth nerve for the upper teeth. This application upon the face, however, need not be made unless the teeth are very difficult to extract, and prolonged anesthesia is desired. It is seldom necessary to use the entire contents of a tube for a single operation; one-quarter of it will usually produce complete anesthesia of the parts. The opening in the tube can then be closed and the contents preserved for a subsequent operation. The writer has employed chloride of ethyl in over three hun- dred minor surgical operations with uniform success. It is a most satisfactory local anesthetic in the extraction of teeth, lancing of abscesses, removal of small tumors, opening the maxillary sinus, extraction of the tooth pulp, and in the prepa- ration of roots of teeth and the fitting of bands and caps in crown- and bridge-work. EucAiNE Hydroohlorate^ "A." Derivation. — Eucaine hydrochlorate "A" is obtained by the action of one molecule of ammonia upon three molecules of aceton which forms triacetonamin. This is then transformed into dry triacetonamincyanhydrin by hydrocyanic acid. This compound when saponified becomes triacetonall?;amin- carbonic acid, ammonia being given off in the process. When benzylated and methylated we get n-methyl-benzoyl- tetramethyly-oxjrpiperidincarbonic acid-methylester, or eucaine. As will be apparent from this synthesis, eucaine is not a coal-tar product. ANESTHETICS. 97 Properties and Actions. — Eucaine (A) is a white, neutral, crystalline powder, soluble in ten parts cold water, making about nine per cent, solution. This solution is stable and may be boiled without suffering deterioration. It may be employed in all cases where cocaine is used and in similar strength or stronger, since the two drugs are quite similar as regaras the rapidity, intensity, and duration of anesthesia; eucaine, how- ever, being much less toxic. Therapeutics. — Eucaine is employed as a local anesthetic for minor surgical operations, and, as has been indicated, the only important difference of this drug and cocaine, physiologi- cally or therapeutically, is the difference in their toxic effects. It is claimed, after many careful experiments, that the pulse is not materially affected by the use of eucaine, either in rate or character. Some writers have stated that unpleasant disturb- ances of sensation follow the use of this drug, particularly when used upon the pharynx. These disturbances, however, are less unpleasant and less marked than those produced by cocaine, and are more transient, and, speaking generally, after the lapse of an hour from the time of application, the subjective sensa- tions may be described as normal. Dental Uses. — In dental practice, eucaine, from two to five per cent, solution, is employed as a local anesthetic in the ex- traction of teeth; it is applied locally, by freely bathing the parts, for lancing painful abscesses; is injected hypodermatically in minor surgical operations in the mouth, such as the removal of small tumors, necrosed bone, and in operations upon the antrum of Highmore. Eucaine may also be employed, cata- phorically, for the obtunding of sensitive dentine, the removal of the dental pulp, etc. The writer has secured very satisfactory results with a ten per cent, solution of the drug, both as a local anesthetic in operations upon the antrum, and in conjunction with cataphoric instruments in the usual dental operations. 98 DENTAL PATHOLOGY AKD DENTAL MEDICINE. STIMULAE^TS. Stimulants are medicinal agents whicli increase organic activity. The most powerful and rapid in action, though tran- sient in effect, are termed diffusible stimulants, while the local stimulants, which are of a vegetable nature, containing a vola- tile oil, are termed aromatic. Among the first class are such agents as the alcoholic prep- arations, ammonia, camphor, ether, nitrite of amyl, myrrh, nor- mal saline solution, coca, caffbae, etc. The principal members of the class of aromatic stimu- lants are capsicum, oil of cloves, peppermint, etc. Heat and cold also act as local stimulants. Alcohol, C2HgO. Derivation. — Alcohol is obtained by repeated distillations from the product of fermented grain or starchy substances, easily converted into grape sugar, which in the presence of and by the growth of low vegetable organisms (the yeast plant, etc.) splits up into alcohol and CO^. Commercial alcohol contains about 90 per cent, of absolute alcohol with 10 per cent of water. Properties and Action. — Alcohol is a colorless, inflammable fluid, wholly vaporizable by heat, and unites in any proportion with water and ether. It possesses a pungent odor and burning taste. All of the alcoholic preparations are powerful diffusible stimulants, causing general exhilaration of spirits. In large doses, however, it is a depressant, producing mus- cular inco-ordination and the effects of narcotic poisons, ending in delirium, coma, and death. The Most Important Alcohols are: — Methylic Alcohol, C^Ufi, methyl hydrate, wood spirit. Ethylic Alcohol, C2HgO, ethyl hydrate, grain spirit. Amylic Alcohol, C-H^oO, amyl hydrate, potato spirit, also occurs with the ethylic alcohol, in excessive distillations of fer- mented grain. STIMULAA'TS. 99 Principal Preparations of Alcohol: — Absolute Alcohol, rarely obtainable in the shops, however, stronger than 98 per cent. Alcohol contains about 91 per cent, of absolute alcohol. Alcoholis Dilutum contains equal parts of alcohol and water. Spiritus Frumenti, whisky from rye, corn, barley, and potatoes, contains from 45 to 50 per cent, of alcohol. Rum, obtained by the distillation of fermented molasses. Wines — ^port wine, sherry white wine (made by fermenting the juice of the grape without the seeds, stems, or skins) ; red wine (from the juice of grapes with their skins) ; champagne, claret, Hhine, etc. These contain from 5 to 40 per cent of alcohol. Beer by slow fermentation, contains 2 to 3 per cent, alcoliol. Ale, by rapid " •' 2 to 6 " " Porter and stout '• 4 to G " " Therapeutic Uses. — The alcoholic preparations are most val- uable agents in disease, for appropriate cases; they are em- ployed as stimulants in acute inflammations, such as pneu- monia, pleurisy, bronchitis, phthisis, and in the last stages of typhoid fever, diphtheria, acute neuralgia, etc. In insomnia from cerebral anaemia, small doses of some alcoholic stimulant at bedtime are found beneficial. In poisoning by cardiac de- pressants and snake venom, alcohol, freely sustains the heart. In chloroform anesthesia, an ounce of whisky beforehand will sustain the heart and prolong narcosis. Dental Uses.- — In the administration of nitrous oxide gas, a small quantity of wine taken beforehand will often be found beneficial, increasing the heart's action at about the time the effects of the anesthetic are passing off. In painful operations upon the teeth, I have found small doses of sherry or brandy to be verv beneficial. 100 DENTAL PATHOLOGY AND DENTAL MEDICINE. As a styptic, it arrests hemorrliags by coagulating the blood by its effects "upon albumin, and contracts the mouth of the vessels by its astringent properties. For suppurating wounds it is a useful antiseptic dressing. For the treatment of soft and sensitive dentine, and for drying cavities preparatory to filling, absolute alcohol is generally an efficient agent; after drying the cavity with cotton or bibulous paper, it should be bathed v^ith alcohol, which evap- orates rapidly and causes the almost perfect absorption of moisture from the dentine. Treatment of Acute Alcoholism. — ^Evacuate the stomach, administer ammonia cautiously by inhalation, apply warmth to the extremities and cold affusion to the head, and, if need be, artificial respiration. * . Ammonia. • Medicinal Properties and Action. — It exists most com- monly in the form of ammonia gas, NHg; which, dissolved in water, is the aqua ammonise of conunerce. It is intensely alki- line, and is an irritant to the mucous membrane. When inhaled it. acts as a stimulant, especially as an antagonist of cardiac de- pressants. Prolonged inhalation induces spasmodic coughing, a sense of suffocation, and inflammation and oedema of the glottis; when swallowed, the aqua sets up violent inflammation of the passages and stomach. The salts of ammonia, in medicinal doses, are stimulating expectorants, and stimulate the heart's action; while in large doses or continued use they produce rapid emaciation, by im- pairing digestion and increasing tissue waste. In large doses they also injure the red blood corpuscles. Principal Preparations: — Aqua ammoniae, water of ammonia, containing 10 per cent, of the gas in water. Dose, "niv-xxx, diluted. STIMULANTS. 101 Aqua ammoniae fortior, containing 28 per cent, of the gas in solution. Ammonium carbonate. Dose gr. ij-x. Ammonium chloride, sal ammoniac. Dose, gr. j-xx. Ammonia spirits (a 10 per cent, solution of aqua ammoniae in alcohol). Dose, "nix-Sj, diluted. Aromatic spirits of ammonia, the carbonate with aro- matics (oil of lemon, lavender, etc., and alcohol and water). Dose, TTLx-^ij. Ammonia liniment, aqua ammonias, 30 per cent., and cot- ton-seed oil, 70 per cent. Ammonium nitrate, used in preparing nitrous oxide gas. Ammonium sulphate, used in preparing other ammonium salts, etc. Camphor^ CjoH^gO. Source. — Camphor is a white, concrete, and translucent gum, obtained from the volatile oil of the camphor laurel, an ever- green tree indiginous in China, Japan, Formosa, etc. Refined camphor is prepared in large circular cakes, one to two inches thick. Properties and Action. — Camphor is slightly soluble in water (about 1 to 1300), but freely in alcohol, ether, chloroform, oils, and mill^. Alcohol forms a 75 per cent, solution. It has a penetrating, fragrant odor, a bitter, pungent taste, leaving a slight sense of coolness. It is a stimulant, anodyne, diaphoretic, antiseptic, and irritant. In medicinal doses it temporarily increases the heart's action, stimulates respiration and mental activity, promotes perspiration, and allays pain and spasm. Large doses depress the heart and excite narcotic symptoms, and have proved fatal. 102 DENTAL PATHOLOGY AND DENTAL MEDICINE. Principal Preparations: — Aqua camphorae, camphor water (8 parts of camphor to 1000 of distilled water, with 16 parts of alcohol to aid in the suspension of camphor). Dose, 3j-iv. Spiritus camphorae, spirit of camphor (camphor, Siv, alco- hol, Oj). Dose, TTLv-xx. Linimentum camphorae, camphor liniment (camphor 1 part to olive oil 4 parts). Linimentum saponis, soap liniment (soap 10 parts, cam- phor 5, oil rosemary 1, alcohol 70, water 15). Is an anodyne and mild irritant for sprains, rheumatic pains, etc. Dental Use. — In dental practice the spirit of camphor is sometimes employed by local application to allay the pain of sensitive dentine, and that which sometimes follows the ex- traction of teeth, and the wounding of pulps of teeth. Cam- phor is also employed in the treatment of putrescent root canals of teeth. It is also one of the ingredients of the celluloid base for artificial teeth. Nitrite of Amyl, C.H^^NOg. Derivation. — Nitrite of amyl is produced by the action of nitric or nitrous acid upon amylic alcohol. Properties and Action.— Nitrite of amyl is a clear, yellow- ish, oily liquid. It has an ethereal odor, and is very volatile and inflammable; it is insoluble in water, but soluble in alcohol, ether and chloroform. It is used by inhalation, causing great cardiac activity, vascular dilatation, flushing of the face, a sense of fullness of the brain, and complete resolution of the muscular system. It is a muscle poison, and when the vapor is applied directly to the muscular or nervous tissues it arrests their functional activity. Dental Use. — Nitrite of amyl, being a powerful stimulant to the heart, is employed in syncope and chloroform narcosis. It is also used in epileptic attacks and other convulsive or spas- STIMULANTS. 103 modic diseases. Cases are reported where nitrite of amyl has restored the patient after artificial respiration had failed. Care, however, must be observed in its use, as it is a powerful and dangerous agent. Dose of nitrite of amyl by inhalation is from TTLij to TTLv. JSTot more than two or three drops should be administered to weak and nervous patients who are susceptible to its influence. Myrrh. Source. — Myrrh is a resinous exudation from a small tree grown in Arabia and the northeastern coast of Africa, known as the Balsamodendron myrrha. It is a spontaneous exuda- tion from the stems of the tree, which collects in small masses upon the bark. Properties and Action. — Myrrh is brittle and is easily pul- verized. It is of a reddish-yellow color, translucent, with an aromatic taste and a peculiar fragrant odor. When pulverized the powder is of a light yellow color, if pure. In medicinal doses, myrrh is a stimulant and astringent. It stimulates the digestive organs and improves the appetite, but in larger doses it acts as an irritant to the gastro-intestinal membrane. It is employed externally as a local application to inflamed, iilcerated, and relaxed tissues, for stimulating and astringent effect. Dose — Powdered myrrh, gr. x to ^ss, in pill form or sus- pended in water. Tincture of myrrh, ^ss to j (myrrh Biij, alcohol Oij). Dental Use. — The tincture of myrrh, diluted, forms an ex- cellent gargle and mouth-wash, and a stimulating lotion for spongy and inflamed gums. The powder is employed as an ingredient of many dentifrices for its astringent properties. Capsicum. Source. — Capsicum, or Cayenne Pepper, is the fruit of Cap- sicum fastigiatunfhj a plant of tropical Africa and America. Its 104 DENTAL PATHOLOGY AND DENTAL MEDICINE. pungent odor and hot taste are due to its very acrid and volatile principle, called capsicine. Medicinal Properties and Actions. — Capsicum in medic- inal doses is a powerful stimulant. It produces a sensation of warmth in the stomach, and a general glow over the body; it stimulates the circulation and digestive process, but in ex- cessive doses it acts as an irritant poison. Preparations : — Tincture Capsicum. Dose, "niv-Sj. Powdered Capsicum. Dose, gr. v-x in pills. Emplastrum Capsicum. A most excellent plaster. Dental Use. — Capsicum in tincture or plaster form, pre- ferably the latter, is very serviceable in dental periostitis, as it aids in establishing resolution or hastens suppuration. It is also an excellent stimulating gargle, tin«t. capsicum, 5ss to rose water, Sviij. Oil of Clo\^s. Source. — The oil of cloves is obtained from the dried, unex- panded flowers of the Eugenia caryophyllata, an evergreen tree of the myrtle order, a native of the Indies. Properties and Actions. — The oil of cloves, when fresh, is a clear and colorless preparation; it has a pungent, spicy taste, and a fragrant odor. Is an aromatic stimulant, irritant and antiseptic. It is sometimes administered to relieve nausea, and prevent griping when combined with purgatives, also to modify the action of other medicines. Dose, TTtj-v. Dental Use. — The oil of cloves is employed in dental prac- tice to relieve odontalgia, by introducing two or three drops into the carious cavity of the aching tooth, relieving the pain by its stimulating effect upon the pulp. It is sometimes used for the same purpose in combination with other agents, and has the effect of rendering carbolic acid more pleasant, without in- terfering with its action. It is used also by microscopists to clarify preparations for mounting. STIMULANTS. 105 Eugenol (C^qHj^oO.O is an active principle of oil of cloves. It is sometimes called an acid, as it possesses some acid quali- ties. It is a clear, colorless oil, and its odor and taste resemble those of the oil of cloves. It is an excellent antiseptic for dental uses. Peppermint. Source. — ^Mentha piperita, or peppermint, is grown every- Vfhere, and as a plant is familiar to every one. The leaves and tops are used for medicinal purposes. Properties and Actions. — The properties of peppermint are due to a volatile oil, in which form it is generally used. It is an aromatic stimulant, carminative and antispasm.odic, and local anodyne and anesthetic when evaporation is prevented after being applied to the surface. Preparations : — Oil of Peppermint (consisting largely of menthol). Dose, mj-v. Peppermint Water (2 parts of the oil to 1000 of distilled water). Dose indefinite. Essence of Peppermint (10 per cent, of oil with 1 per cent, of the powdered herb in alcohol. Dose, trtx-xxx. Dental Use. — Local anodyne and anesthetic. Sodium Chloride. Normal saline solution (0.6 per cent, sodium chloride). In emergency cases it is sometimes necessary to inject a stimulant directly into the vein, and as this saline solution correspends so closely in salinity to the blood serum it is regarded today one of the most important means of stimulation. Serious loss of blood, and extreme depression or collapse would indicate its use. Normal saline solution is prepared by dissolving 6 parts so- dium chloride in 1000 parts of sterile water, and as has been indicated is injected intravenously. 106 DENTAL PATHOLOGY AND DENTAL MEDICINE. TONICS. Tonics are agents which give healthful activity and vigor to the functions, gradually imparting strength and tone to the system, that is, without preternatural excitement. They are divided into vegetable and mineral tonics. Principal among the vegetable tonics are cinchona, nux vomica, digitalis, cimicifuga, and eucalyptus. While the principal mineral tonics are the preparations of iron, arsenic, zinc, sulphuric acid, nitric acid, muriatic acid, etc. Cinchona (Peruvian Bark). Source. — Cinchona is the bark of any variety of cinchona. The different species of this tree are natives of the mountains of western South America, especially in Peru and Bolivia, though they have been planted and are grown in Indi% Ceylon and Burmah. The medicinal properties of these barks depend upon the alkaloids they contain, which are in varying proportions, usu- ally from 3 to 4 per cent., at least 2 per cent, of which is quinine, this being the most important. Principal preparations of cinchona and its alkaloids are as follows : Powdered cinchona. Dose, gr. x-3iij. Tincture cinchona (strength 20 per cent.). Dose, 3j-,^ss. Extract cinchona (in pill). Dose, gr. j-x. Sulphate of Quinine. Dose, gr. j-xx. Sulphate of cinchonidine (one-half the strength of qui- nine). Dose, gr. ij-xxx. Much used in hospital and dispensary work. Properties and Actons. — The different varieties of cin- chona are named according to their color. Yellow cinchona — cinchona flava; pale cinchona — cinchona pallida; red cinchona • — cinchona rubra. The powder from the yellow bark is of an TONICS. 107 orange color; has a more bitter taste than the other barks, con- taining more of the alkaloid quinine. Cinchona is a bitter tonic, astringent, antipj'^retic, and antiseptic. The alkaloid quinine is preferable for ordinary use, as a much larger quan- tity of the powdered bark is necessary to obtain the full effects, often causing derangement of the stomach, headache, and con- stipation. Dental Uses. — In dental practice quinine is employed in from five to ten grain doses as a tonic, and in the treatment of neuralgia when due to malaria. Cinchona is also used as an antiseptic. "The powder dusted over unhealthy wounds will arrest putrefaction and promote healthy cicatrization. Quinine will destroy minute organisms, and preserve substances from decomposition."* Cinchona is also employed for its antiseptic and tonic properties as an ingredient in certain dentifrices. Nux Vomica. Source. — Nux vomica is the seeds of the Stryclmos nucis vomica, a tree of the family Strychnoides, which grows in India. These seeds have been long sold in the shops under the names of nux vomica, bachelor's buttons, poison nuts, etc., and for a long time were used only for such purposes as poisoning rats. Medicinal Properties and Actons. — Nux vomica contains two all'^ialoids, strychnine and brucine, to which its medicinal properties are chiefly due. Brucine has only y^,, the strength of strychnine, but they are otherwise identical, physiologically and therapeutically. In small doses nux vomica is a bitter tonic, exciting the secretions and stimulating the functions of the body. In full doses (strychnine gr. Y^q) the function of the spinal cord is exalted, causing tetanic spasms of the extensor muscle, *Gorgas' ''Dental Medicine." 108 . DENTAL PATHOLOGY AND DENTAL MEDICINE. the lower jaw is stiff, the pupils dilated, and the face wears an unmeaning smile. In toxic doses (strychnine gr. ^^2) the function of the spinal cord is paralyzed, respiration is arrested, death following from asphyxia; consciousness is preserved, however, until CO2 nar- cosis takes place. Treatment of Strychnine Poisoning. — The antidote is tannic acid, which forms an insoluble tannate ; then the stomach pump should be employed or emetics administered, after which the patient should be kept perfectly quiet. The antagonists are chloral, chloroform, and potassium bromide; the last named, though, is rarely used, on account of its being so slow of action. The bladeer must be evacuated frequently, lest a reabsorp- tion of the poison take place. Preparations : — ^ Abstract of Nux Vomica. — Dose, gr. V2 gradually in- creased to gr. j. Tincture of Nux Vomica (20 per cent, of the drug). Dose, TUJ-x. Extract of Nux Vomica. Dose, gr. i/g-j. Fluid Extract of Nux Vomica. Dose, nij-v. Sulphate of Strychnine. Dose, gr. yioo"V2o- Dental Uses. — Where a cardiac or nerve tonic is required, nux vomica and its chief alkaloid hold the first rank. Digitalis. Source. — Digitalis, or foxglove, is the leaves of Digitalis purpurea, or purple foxglove; the leaves of the second year's growth are considered the best. The plant grows wild in Europe, and is cultivated in this country, where it is sometimes seen in private gardens, grown for its beautiful spike of purple flowers. The Shakers cultivate it quite extensively for the drug market. TONICS. 109 Medicinal Properties and Actions. — Digitalis is chiefly used in disease for its tonic and diuretic properties, its tonic effect upon the heart, principally; though the heart is slowed by its action, its force is at the same time increased. For the full cardiac effects the recumbent posture should be maintained. When the doses are large, severe gastric disturbance is caused. In toxic doses, the muscles and peripheral nerves are paralyzed; respiration is first slowed and then becomes rapid and feeble; coma and convulsions followed by death from the sudden paralysis of the heart. Preparations and Doses: — Digitalis (the leaves). Dose, gr. ss-iij. Abstract of Digitalis. Dose, gr. %^-j (strength 200 per cent.). Extract of Digitalis. Dose, gr. ^ / ^.-]. Fluid Extract of Digitalis. Dose, Tixj-iij. Tincture of Digitalis (15 per cent.). Dose, iilv-xx. CiMICIFUGA. Source. — Cimicifuga, or the black snakeroot, is the root of the Cimicifuga racemosa, a common plant in the United States. Medicinal Properties and Actions. — Cimicifuga has a bitter and nauseous taste, somewhat resembling that of opium. It is an efficient cardiac tonic, antispasmodic, diaphoretic, and diuretic. It is feebler in its action than digitalis, and should be used more frequently when the latter drug is indicated. Preparations and Doses: — Fluid Extract of Cimicifuga. Dose, tiiv-xxx. Tincture of Cimicifuga (20 per cent, in strength). Dose, TUxx-lx (3j). Eucalyptus. Source. — Eucalyptus is obtained from the leaves of the Eucalyptus globulus, or "blue gum tree," a native of Australia, but is now grown in Northern Africa, Southern Europe and in the United States. 110 DENTAL PATHOLOGY AXD DEKTAL MEDICINE. Properties and Actions. — The leaves are the only portion of the tree which possesses medicinal qualities, the fresh being more active than the dried leaves. Their medicinal properties are due to a volatile oil, called oleum eucaljTpti, which contains three oils, eucalyptene, turpene, and cymol, which distilled over at different temperatures, the first product being the most im- portant. Eucalyptus promotes appetite and digestion, and in- creases the heart's action. In large doses it causes indigestion, nausea, diarrhoea, and great muscular weakness, and if continued will cause irritation and congestion of the kidneys. It is eliminated by the skin, bronchial mucous m.embrane, and kidneys, the secretions of which become strongly odorous, owing to the presence of the oil. Eucalyptus is also an antiseptic, disinfectant, sedative, and diaphoretic, "and has anti-malarial properties, absorbing noxious germs, as well as enormous quantities of water from the soil, and by its emanations purifying the atmosphere in the vicinity. It is largely cultivated in malarial districts for these properties, and has rendered habitable a portion of the deadly Koman Campagna."* Preparations of Eucalyptus: — Extract. Dose, gr. j-xv. Fluid Extract. Dose, ttLxx-3j. Tincture. Dose, f^ss-ij. Oil. Dose, niv-xx in emulsion or capsules. Dental Use. — In dental practice the oil of eucaljiptus is employed either alone or combined with iodoform, for its antiseptic properties, in the treatment of putrescent pulps of teeth and chronic alveolar abscesses. This combination has also proven very efficient in the treatment of necrosis and caries of the bone of the jaws. ♦Potter's "Materia Medica." TONICS. Ill By taking- advantage of tlie solvent effects of eucalyptol upon the giitta-percha, it will be found of great benefit in the insertion of fillings of this material. Iron. Ferrum, or ironj, is a metal of a bluish-gray color, fibrous in texture, is hard, ductile, malleable, and magnetic. Chemical analysis demonstrates the presence of iron in the blood, 1 part to 230 of red corpuscles, also in the gastric juice, chyle, bile, lymph, urine, milk, and pigment of the eye. Properties and Actions. — Iron taken into the stomach in the metallic state, meeting with the acids of that cavity, is dissolved, which causes an evolution of hydrogen gas, and gives to the iron molecular activity. Given tnedicinally in small doses, the salts of iron act through and upon the blood, improv- ing its quality and increasing the number of red corpuscles; they also promote the appetite and improve digestion, and hence it is recognized as one of the most efficient tonics. In large doses these salts cause nausea and vomiting and act as irritants. Or the prolonged administration of small doses exhausts the gastric glands by over-stimulation. Monsel's preparations of iron are principally used exter- nally, for hemorrhage, and are considered to be among the very best styptics in use. When internally employed it is for their hemostatic effect in hemorrhage from remote organs. In admin- istering iron care should be exercised, as nearly all the prepara- tions are more or less astringent, and act injuriously on the teeth. Contra-indications. — Iron should never be given when plethora (a superabundance of blood) exists, especially when accompanied with a hemorrhagic tendency. Principal Preparations : — Tincture of the Chloride of Iron. Dose, niv-xx. 112 DENTAL PATHOLOGY AND DENTAL MEDICINE. Powdered Sulphate of Iron, Monsel's Powder. Dose, gr. ss-iij, in pill; used also as a styptic. Solution of Subsulphate of Iron, or Persulphate, Monsel's Solution. Possesses powerful astringent properties; used only as a styptic. Dental Uses. — ^In dental practice the chief indications for iron are where hemorrhage follows the extraction of teeth, or from any other cause, such as wounds of the gums and mucous membrane. IVTonseFs solution or powder is employed for this purpose. See chapter on Extraction of Teeth. AeseniC;, As. Properties. — Arsenic is a brittle, granular metal, of steel- gray color, is very combustible, and volatilizes before melting, the vapor having an odor like that of garlic. It is a powerful poison, not of itself, however, but by virtue of the facility with which it absorbs oxygen. It is generally found in cobalt ore. It is not employed as medicine in its native state. Preparations : — Arsenious Acid (?), White Arsenic, "Ratsbane." Dose, gr Veo to Vio- Solution of Arsenious Acid, 1 per cent, solution (strength, Vioo) with hydrochloric acid and distilled water. Dose, TTLij-x, after meals. Solution of Potassium Arsenite, Fowler's solution (strength y^oo). Dose, TTlij-x, after meals. White Oxide of Arsenic (AsgOg), Arsenious Acid, is in the form of irregnilar solid lumps, having a chalky appearance externally, though it is often perfectly transparent internally. It is usually furnished in the shops, however, in the form of a fine white powder, and is often adulterated with chalk or lime. It is odorless and has a faint sweetish taste. Physiological Actions. — In small doses, arsenic is a gen- eral tonic, promoting the appetite, digestion, and cardiac action, TONICS. 113 stimulates mental activity, and causes rotundity of form and ■ clear skin. In large doses it becomes a violent corrosive poison, creates skin eruptions and itching of the eyelids, nausea, dysentery, and an irritable and feeble heart, death following from narcotism. Externally, it is a powerful escharotic. Toxicology. — The antidote to arsenic is the hydrated oxide of iron. After the prompt evacuation of the stomach this should be administered, the dose being eight times the quantity of the poison taken. This should be followed by mucilaginous or oily drinks, to protect the mucous membrane, and iodide of potassium or alkaline mineral waters, to promote elimination. Tests for Arsenic. — There are a number of tests for arsenic, the following being considered the best : If in a solid state, place the suspected material on burning charcoal, when the arsenic, if present, will become deoxidized and emit the garlic odor spoken of above. When in an aqueous solution, it may be detected by adding sulphide of ammonium, which produces a yellow sul- phide of arsenic, or the addition first of ammonia, then a small quantity of nitrate of silver, will produce a light yellow arsenite of silver. Again, the addition of potassa and sulphate of copper produces a light gTeen arsenite of copper. Marsh's Test. — The most delicate test for arsenic consists in subjecting the material to the action of nascent hydrogen.* The arsenic is deoxidized and forms with the hydrogen arseni- uretted hydrogen gas; this also has the peculiar odor of garlic, burning with a bluish-white flame, which deposits metallic arsenic in the form of a black spot on the surface of a cold plate if held directly in the flame. Reinsch's test consists of boiling the material suspected of containing arsenic with hydrochloric acid and copper foil, when, if arsenic is present, it will manifest itself in the form of a coating of gray metallic arsenic upon the foil. ♦Nascent hydrogen is evolved by the action of diluted sulphuric acid on zinc. 114 DENTAL PATHOLOGY AJSD DENTAL MEDICINE. Dental Uses. — Arsenic is employed in dental practice for its devitalizing power in destroying the vitality of the pulps of teeth. It is generally combined with other agents, in the form of paste or fibre, for this purpose. But I have found the white arsenic alone to act very happily when applied to the pulp and retained by a small pledget of cotton which had been 'previously saturated with cocaine. The cavity should be completely se- cured, that none of the arsenic come in contact with the part outside of the tooth. The quantity to be used for this purpose is about the ^ /^^ of a grain, and the time required is usually about 24 hours, though there are instances where 48 hours or more are required to thoroughly destroy the vitality. ZiNC^ Zn. Properties. — Zinc is one of the metallic elements — it is very hard, has a bluish-white color, and the fresh surface has considerable lustre, but is soon dulled, from the facility with which it oxidizes. Principal Preparations: — Zinci Oxidum. Dose, gr. j-x, insoluble in water. Zinci Acetas. Dose, gr. i/4-ij; as a lotion, gr. ij to Sj of water, in which it is very soluble. Zinci Sulphas. Dose as a tonic and astringent, gr. Yio-j. As an emetic, gr. vj in §iv of water, in tablespoonful doses, re- peated every few minutes until emesis takes place. Zinci Carbonas Praecipitatus. As ointment, or dusted over wounds as a protection. Zinci lodidi. Dose, gr. ss-v, in the form of a syrup. Zinci Chloridum, tonic and escharotic. Dose, gr. ss-ij, well diluted. Zinci Chloridum Liquor, solution of chloride of zinc, 1/2 to 1 per cent, in strength. TONICS. 115 Physiological Actions. — The salts of zinc are more or less poisonous, the soluble salts, the acetate, sulphide, and chloride being" corrosive poisons. In small doses they are tonic and astringent, while in larger quantities they are strong emetics. The sulphate is a specific emetic, acting without much depression. The chloride is a powerful and penetrating escharotic. It is also a useful deodorizer and disinfectant. "When applied to malignant and indolent ulcers, it promotes healthy granula- tions, and when topically applied it not only destroys the dis- eased structure, but excites a new and healthy action of sur- rounding parts." The antidotes for zinc poisoning are, the white of an egg, carbonate of soda, magnesia, etc. Dental Uses. — In dental practice the chloride of zinc (ZnCl.J is a valuable agent. It is employed as an obtunding agent for sensitive dentine — the sensitive surface being pre- viously bathed with chloroform, which will modify the painful action of the chloride. It has also been employed as a styptic to arrest superficial hemorrhage from a wound of the gum during the filling of the teeth. It induces union of the wounded parts by first intention, by its effect upon the glutinous matter, also as an injection for chronic alveolar abscess, and in diseases of the antrum of Highmore. It is also used in the recession of the gum and the absorption of the alveolar process from the necks of the teeth. The application can be conveniently made by means of a piece of orange wood, so shaped as to permit of its being introduced beneath the gums. The chloride of zinc, in solution, is also used as one of the ingredients of the filling material known as the oxychloride of zinc, the other ingredient being the oxide of zinc. The combination of these two forms of zinc makes an ex- cellent capping material, and is probably one of the best mate- rials for root filling. 116 DENTAL PATHOLOGY AND DENTAL MEDICINE. The oxide of zinc, ZnO, is sometimes employed, combined with carbolic acid, in the form of a paste, for capping exposed pnlps; it is also one of the ingredients of the zinc filling materials, and of the celluloid base of artificial teeth. The sulphate of zinc, ZnSO^THgO, is sometimes employed in disease of the antrum of Highmore, and ulcerations of the mucous membrane, for its stimulant and astringent properties. Sulphuric Acid^ HgSO^. Properties. — Sulphuric acid, or oil of vitriol, is a dense, inodorous, colorless, oily, and corrosive liquid. It consists of not less than 96 per cent, sulphuric anhydride and about 10 per cent, of water. Preparations: — Sulphuric Acid. Used as an escharotic or caustic. Diluted Sulphuric Acid (10 per cent, of the acid to 90 per cent, of water). Dose, niv-xv, well diluted. Aromatic Sulphuric Acid (Elixir of Vitriol). Sulphuric acid diluted with alcohol and flavored with ginger and cinna- mon (strength 20 per cent.). Dose, Tltv-xxv, well diluted. Action. — The action of sulphuric acid in its different forms is as follows: Aromatic sulphuric acid, tonic and astringent; diluted sulphuric acid, tonic, astringent, and refrigerant (in fevers) ; sulphuric acid, escharotic. Treatment of Sulphuric Acid Poisoning. — Being a cor- rosive poison, sulphuric acid causes death from asphyxia (the suspension of vital phenomena, from the non-oxygenation of the blood — an excess of carbon dioxide). Administer alkalies, as washing soda, magnesia, lime water, soapsuds, etc., to neu- tralize the acid, and mucilaginous drinks freely, to protect the mucous membrane. Stimulants, opium, aramonia intraven- ously, to combat the depressed condition of the vital powers. Dental Uses. — The concentrated sulphuric acid is employed in dental practice as a caustic; in the laboratory, in a diluted TONICS. 117 state, for the cleansing of metals before and after soldering ("the acid bath"). It is also used in the manufacture of pyroxylin — gun cotton. Aromatic sulphuric acid is more agreeable for use in the mouth, while its action resembles that of diluted sulphuric acid. It is a valuable agent in the treatment of pyorrhoea alveolaris and necrosis of the maxillary bones, stimulating the parts to healthy action. It is also employed in the treatment of chronic alveolar abscesses, in combination with a few drops of tincture of capsicum. Nitric Acid, HN0„. Properties. — Nitric acid, or aqua fortis, is a highly caustic liquid, very volatile, its fumes being corrosive and suffocating, and in the pure state is colorless and transparent, but that usually found in shops is of a yellow color, owing to the pres- ence of nitric peroxide. Strong nitric acid is never given in- ternally; it is used in the form of the diluted nitric acid, 10 per cent, absolute acid. Dose lUiij-x, well diluted. Action. — Pure nitric acid is a powerful caustic and escha- rotic, and is rarely used except as an application to foul, indo- lent ulcers, or to warts. The diluted acid is a tonic, alterative, and refrigerant, used as a drink in fevers. It is, as are most mineral acids, injurious to the teeth; hence, care should be taken in its use. It should be taken through a glass tube or quill, and followed by an alkaline mouth wash. It is not as agreeable to the stomach as diluted sulphuric acid. The antidotes for nitric acid poisoning are magnesia or soap and mucilaginous drinks. Dental Uses. — ^Nitric acid is employed in dental practice as a caustic for malignant ulcers of the mouth, and has been used for devitalizing pulps of teeth when nearly exposed by mechanical abrasion. It is also used in combination with hydrochloric acid (aqua regia) as a solvent for gold. 118 DENTAL PATHOLOGY AND DENTAL MEDICINE. Phosphoric Acid, HgPO^. Properties. — Phosphoric acid is a solid, colorless compound, soluble in water and vitrifiable by heat (converted into glass). It is obtained from bones, where it exists in combination with lime. Diluted phosphoric acid is the form in which phosphoric acid is usually employed in medicine. It contains 10 per cent, of the absolute acid. Dose, "niv-xx. Action. — Phosphoric acid is tonic and refrigerant, and in large doses an irritant poison. It has been employed externally in the treatment of osseous tumors and caries of the bones. Glacial phosphoric acid, HOPO-, is obtained from calcined bones. They are first treated with sulphuric acid, "which pro- duces an insoluble superphosphate of lime, then dissolving out the latter salt and saturating it with carbonate of ammonia, which generates phosphate of ammonia in solution, and, finally, obtaining the phosphate of ammonia by evaporating t^ dryness, and then igniting it in a platinum crucible. The ammonia and all of the water, except one equivalent for each equivalent of the acid, are driven off, and the glacial phosphoric acid remains. It is a white, transparent, fusible solid, generally in the form of sticks, inodorous, and sour to the taste. It slowly deliquesces, and is sparingly soluble in water, but freely soluble in alcohol."* Dental Uses. — Phosphoric acid has been employed in dental practice as a local treatment of osseous tumors and caries of the maxillary bones. Glacial phosphoric acid is employed as one of the ingre- dients of the plastic filling material, known as oxyphosphate of zinc, the other ingredient being the white oxide of zinc. Hydrochloric Acid, HCl. Properties. — Hydrochloric or muriatic acid is nearly color- less when pure, but that usually found in the shops is of a pale yellow color, being contaminated with chlorine, iron, and other *Gorgas' "Dental Medicine." ANTIPYRETICS. 119 substances. It is volatile, emitting a dense white and suffocat- ing vapor; taste very acid and caustic. Actions. — Hydrochloric acid is caustic, escharotic, and dis- infectant. The diluted acid administered internally is tonic, refrigerant, and astringent. Diluted Hydrochloric Acid (ten per cent, solution of absolute acid and water). Dose, TTLv-xx. Dental Uses. — It is sometimes a useful application for treatment of ulceration and inflammation of the mucous mem- brane and gums. "The strong acid is employed in the labora- tory for dissolving zinc, in the preparation of a flux for solder- ing certain metals." SEDATIVES. Sedatives are agents which exert a soothing influence — -that is, diminish pain — by lessening the functional activity of organs. The principal agents of this class are opium and aconite (see Anodynes), digitalis (see Tonics), alcohol (see Stimu- lants), chloroform (see Anesthetics), etc. ANTIPYRETICS. Antipyretics are agents which reduce the temperature of fever. They act either by lessening heat production or by radiation of heat. The most prominent of this class are antipyrine, quinine (see Tonics), aconite, alcohol (by increasing heat radiation), also cold bath, ice to the body, etc. Antipyrine, C2oIIj^gN402. Derivation. — Antipyrine is an alkaliodal product of the destructive distillation of coal-tar oil. Properties.— It is a whitish, crystalline powder, soluble in water (one-half its weight of hot and its own weight of cold 120 DENTAL PATHOLOGY AND DENTAL MEDICINE. water) ; less soluble in alcohol, chloroform, and ether ; is slight- ly bitter and odorless. It may be administered hypodermically ; IS non-irritant to the stomach or the tissues. When combined with ferric chloride it gives a bright-red' color, and with nitric acid a beautiful green color. Actions. — Antipyrine is a powerful and popular antipyretic, a general anodyne, haemostatic, and also possesses mild anes- thetic and hypnotic powers. A full medicinal dose (gr. xxx) produces a stimulant stage of short duration, which is soon followed by profuse sweating, coolness of the surface, slowed pulse, and more or less depression. The temperature in fevers is reduced from 2 to 10 degrees in from 1 to 5 hours, according to the size and continuance of the dose. In health the reduction of the temperature is very slight, and it gives rise to slight nausea and depression. It is eliminated by the kidneys, appear- ing in the urine a few hours after taking. ♦ "In toxic doses its principal influence is exerted upon the blood, altering the shape of the red blood corpuscles, separating the hsematin, and causing decomposition of that fluid."* Dose, for adult, gr. v-xxx; children, gr. j-x. Dental Uses. — Antipyrine may be employed in dental prac- tice for its haemostatic, anesthetic, and anodyne powers. lEEITANTS. Irritants are agents which produce more or less vascular ex- citement or inflammation. They may be either chemical, me- chanical, or nervous. Chemical irritants are those which act by virtue of their atfinity for organic tissue, exciting the action of the capillaries, and causing an afflux of vascular and nervous power to the part to which they are applied. Included in this class are ♦Potter's "Materia Medica." IRRITANTS. 121 iodine, capsicum, (see Stimulants), turpentine, ammonia (see Stimulants), etc. Mechanical irritants are agents or means that cause lesions or inflammation by mechanical operation. Filling material or other foreign substances being forced through the apical fora- men of the root of a tooth will cause sufficient irritation to produce an abscess; and cuts, contusions, etc., are included in this class. Nervous irritants act through the medium of the nerves, as nervous shock, depression, or sympathetic inflammation. Iodine. Derivation. — Iodine is obtained principally from marine plants, though it occurs in cod-liver oil and shell-fish to a limited extent. Properties. — ^Iodine is -a non-metallic element, is usually in the form of bluish-black crystalline plates or scales, having a metallic lustre, a peculiar odor, hot, acrid taste, and is of neutral reaction. It volatilizes at a low temperature, giving off a beautiful purple vapor, is slightly soluble in water (1 in TOGO), readily soluble in alcohol and ether (1 in 12), also in a solution. of chloride of sodium and iodide of potassium. Principal Preparations : — Tincture of Iodine, 8 per cent, in alcohol. Dose, lUj-v. Compound Tincture of Iodine (iodine, 5 per cent., potas- sium iodide, KI, 10 per cent., and water 85 per cent.). Dose, nij-x diluted. Potassium Iodide. Dose, gr. v-xxx. Iodoform, CHI3. Dose, gr. j-v, in pill form. Actions. — Iodine in its elementary state is an irritant to the skin, and is much used in the form of tincture to produce counter-irritation. Internally in small doses it is a stimulant and tonic; it excites a sensation of heat or burning in the stomach, and in 122 DENTAL PATHOLOGY AND DENTAL MEDICINE. large doses acts as an irritant poison. If continued for any length of time, iodine induces great waste and rapid elimina- tion of waste products, causing anaemia and depression. The local irritant effect is diminished when combined with potassium; hence, potassium iodide (aqueous solution of potassa and iodine) is usually employed for internal use, which allows the administration of larger doses and for a greater length of time. Toxicology. — The antidote for iodine is starch, forming an iodized starch, which should then be evacuated from the stomach. Colorless Iodine. — There are a number of methods for bleaching iodine; among them are the following: 1st. Add to a drachm of tincture of iodine six ounces of hot water and twelve grains of phenol; stir with a glass rod. 2d. Iodine is bleached by mixing with carbolic acid; this, carbolate of iodine, combines all the advantages of both agents. Dental Uses. — Iodine is a very valuable agent in dental practice, the tincture being employed locally in the treatment of periostitis, inflarmnation and ulceration of the gums, fun- gous growths, suppurating pulps of teeth, alveolar abscess, and for ulcerations of the mucous membrane; it is often combined with carbolic acid, and for dental periostitis it is generally combined with tincture of aconite; this combination forms an excellent treatment for the incipient stages of this affection, as well as those of alveolar abscesses. Turpentine. Derivation. — Turpentine is a concrete, oleo-resinous exuda- tion from various species of pine, but principally from the "yellow pine." Properties. — Turpentine is in the form of tough, yellowish masses, more or less transparent, inflammable, having a strong, unpleasant odor, and warm, pungent taste. ASTRINGENTS. 123 It is composed entirely of resin and the essential oil known as oil of turpentine, Cj^H^gO. It is soluble in alcohol. The oil is the form mainly used. Actions. — Turpentine is a stimulant, diuretic, antispas- modic, and rubefacient (counter-irritant), and antiseptic ex- ternally. Principal Preparations : — Oil of Turpentine, Spirits of Turpentine, a volatile oil dis- tilled from turpentine. Dose, TTtv-xv in emulsion as a stimulant. Turpentine Liniment. — Resin cerate (a composition of wax, oil, or lard), 65 per cent., oil of turpentine, 35 per cent. Pitch is a resinous exudation from the stem of certain pine, fir, and spruce trees. It melts at the boiling point of water, and softens by the heat of the human body. It is of a dark-brown color, and possesses a well-known odor and taste. It is used principally as the base of plasters. Dental Uses. — Turpentine may be used in dental practice for its rubefacient and antiseptic properties. ASTRINGENTS. Astringents are agents which produce contraction and con- densation of organic tissues, with a tendency to remove morbid affections, arrest hemorrhage and excessive secretions from the mucous membrane. They are divided into two classes, known as vegetable and mineral. The principal vegetable astringents are tannic acid and gallic acid, the chief elements of these being tannin, while the mineral astringents are persalts of iron (see Tonics), alum, sulphuric acid, nitric acid, etc. Tannic Acid, 02^11220^^. Derivation. — Tannic acid is obtained from nut galls. Galls are the excrescence on the twigs of the Dyer's oak, grown in 124 DEXTAL PATHOLOGY AND DEKTAL MEDICINE. Asia Minor and Persia, caused by the punctures and deposited ova (egg) of an insect. Properties. — Tannic acid is obtained in the form of thin, yellowish crystals, inodorous, very soluble in water, less so in alcohol and ether. Actions. — Tannic acid is the most powerful of all vegetable astringents and styptics. It is especially active upon albumin, gelatin, and fibrin, forming therewith insoluble tannates, thus protecting the parts beneath until resolution occurs. Dose, gr. j-xx, in pill. Dental Uses. — Tannic acid is a very valuable agent to the dental practitioner. It is used locally in the treatment of hemorrhage following the extraction of teeth, wounds of the mucous membrane, fungous growths of the tooth pulp, hyper- trophy of the -gums, and to many it has proven beneficial in the treatment of sensitive dentine, a strong solution of tannin being mixed with alcohol. In mercurial salivation, the powdered tan- nic acid, moistened with water, will check the tendency to absorption and the consequent loosening of the teeth, and will render the gums firmer and more comfortable. Glycerite of Tannic Acid (tannin, Sij; glycerin, Sviij), for external use. Ointment of Tannic Acid (tannin, 3j; lard, Sj), for appli- cation to ulcers, etc. Gallic Acid, C^HgOg. Derivation. — Gallic acid is prepared from nutgalls. The powdered galls, in water, are left to the action of the atmos- phere, when the acid, in the form of fine, almost colorless, crys- tals are deposited. Properties. — Gallic acid is obtained in the form of very fine, silky, and almost colorless crystals. It is slightly soluble in cold water (100 parts), and rapidly so in hot water, glycerine, or alcohol. It has a slightly acid and astringent taste. ASTRINGENTS. 125 Action. — Gallic acid is a powerful astringent, styptic, and disinfectant. It is given directly for internal hemorrhage pro- fuse perspiration (night sweats), and excessive expectorations of phthisis and chronic diarrhoea. Dose, gr. v-xx, in pill form. Dental Uses. — in dental practice gallic acid may be used as a styptic in superficial hemorrhages; it is not so efficient, however, as tannic acid. It is employed in the form of a gargle, in acute inflammation of the mucous membrane, etc. For hemorrhage following extraction of teeth. Dr. Bartholomew claims that a tea spoonful of gallic acid in a glass of water, in- ternally administered, is very efficacious. Alum. Source. — Alum is found native in Italy, in the neighbor- hood of volcanoes. It is also obtained from aluminous slate or shale by roasting and exposure to the air. Formula. — The official alum (potassic-aluminic-sulphate) has the formula K2AL24SO4+24H2O. Dried or "burnt alum" has the water of crystallization, 24II2O, driven off by gentle heating, which leaves it in the form of a soft, white powder. Properties. — Alum is a white, transparent salt, crystallizing easily in octahedrons (having eight equal and equalateral tri- angles). It dissolves easily in hot water, and by about fifteen times its weight in cold water; is insoluble in alcohol. It pos- sesses an astringent and sweetish taste. Actions. — When taken internally in large doses, it causes vomiting, purging, and inflammation of the gastro-mucous membrane. As an emetic, powdered alum, in teaspoonful doses is very efficient. Applied locally, it is an excellent astringent to relaxed or bleeding parts. Dose, in powder or solution, gr. x-xl (2®). Dental Uses. — In dental practice, alum is employed as a styptic in alveolar hemorrhage, superficial hemorrhage of the mucous membrane, ulcers of the mouth, etc. It also serves an 126 DENTAL PATHOLOGY AND DEXTAL MEDICINE. excellent purpose as a gargle in ulceration and sponginess of the gums. STYPTICS AND HEMOSTATICS. Styptics are agents which arrest hemorrhage by local appli- cation. They are divided into chemical and mechanical, ac- cording to their action. Chemical styptics coagulate the exuding blood, and at the same time stimulate the tissues to contraction. The principal members of this class are, tannic and gallic acids (see Astringents), persulphate of iron — solution, subsul- phate of iron — powdered (see Tonics), alum (see Astringents), and adrenalin. Mechanical styptics are agents which promote clot forma- tions in the mouths of bleeding vessels. They retard the flow by detaining the blood in their meshes, or absorb it^ until it coagulates. The principal mechanical styptics are spider's web, plas- ter-of -Paris, sandarach varnish, cotton, etc. Adrenalin. Derivation. — Adrenalin is the active principle of the adrenal or suprarenal gland. Adrenalin chloride, 1 : 1000, is a definite product, composed of 1 part adrenalin with 999 parts normal saline solution, and may be diluted to any degree desired by the adding of this solution. This preparation is practically permanent if kept in well stoppered bottles. Under continued exposure to air the liquid becomes brown in color and a sedi- ment is thrown down, when it should be discarded. The raanu- facturers say that adrenalin is about a thousand times as pow- erful as adrenal or suprarenal gland, making the 1 : 1000 solu- tion of the chloride approximately the same strength of the original gland, but freed from all inert matter. Dental Uses. — The adrenalin chloride solution, applied locally is an excellent styptic, and astringent. Its action is ESCilAROTlGS OR CAUSTICS. 127 local upon the muscular tissue of the small blood vessels. It does not coagulate albumen. Its use is indicated in the treat- ment of persistent hemorrhage following the extraction of a tooth, or the removal of a pulp; and in the fitting and setting of crowns, etc., to render the field bloodless. Adrenalin has more recently been recommended for the extirpation of pulps, but extended clinical experience must determine just what value it has in this direction. Hemostatics are agents capable of arresting hemorrhage by internal administration, such as ergot, antipyrine (see As- tringents), the diluted m.ineral acids (see Tonics), etc. Ergot. Source. — Ergot is obtained from a parasitic fungi replacing the grain of rye. It is a diseased state of the grain, occasioned probably by a hot summer succeeding a rainy spring. Corn ergot is obtained from a similar growth upon the Indian corn. Principal Preparations : — Fluid Extract of Ergot. Dose, 3ss-ij. Extract of Ergot. Dose, gr. j-xx. Medical Properties and Actions. — Ergot is a hemo- static, aiding coagulation by slowing the blood current. It is also used to stimulate the contraction of unstriped muscular fibre, particularly those of the uterus, causing continuous labor pains. It has been much used for this purpose in obstetrics, and very often injuriously, causing laceration of the perineum and paralysis of the foetal heart, the natural intermitting con- traction being the most desirable. Dental Uses. — Ergot may be used in dental practice for its hemostatic properties in alveolar or other hemorrhages. ESCHAROTICS OR CAUSTICS. Escharotics or caustics are agents which are capable of de- stroying the life of the tissue with which they come in contact, producing an eschar or sloughing of the tissue. Fire itself is 128 DENTAL PATHOLOGY AND DENTAL MEDICINE. the actual cautery, while the potential cautery (caustic sub- stances) is reijresented by silver nitrate, arsenious acid (see Tonics), carbolic acid, zinc chloride (see Tonics), and the mineral acids (see Tonics), etc. Nitrate of Silver^ AgNOg. Derivation. — ^Nitrate of silver, or "lunar caustic," is made by dissolving silver in nitric acid, and evaporating the solution. The reation being Ag3+4H]Sr03=3AgN03+2H20+NO. Properties. — Nitrate of silver is in the form of colorless, shining crystals, but is readily blackened by mixing with or- ganic matter or by exposure to the light, is very soluble in water, and has a strong metallic and styptic taste. It is often cast in sticks, by first being melted (fusing at 426' F.) and then poured into suitable moulds. Actions. — Nitrate of silver is a powerful caustic and astrin- gent, a heart and nerve stimulant, antispasmodic and sedative. When applied locally to the mucous membrane, ulcers, etc., it first turns the surface white, owing to its union with the coagu- lated albumin, but finally turns to a black color, which is due to the partial reduction of the silver by the sulphuretted hydro- gen contained in the atmosphere. Continued use of nitrate of silver will cause a peculiar blue line in the gums, similar to that from lead poisoning; this is followed by a blue appearance of the skin. The remedy should be discontinued at once when this discoloration is observed. Dose of nitrate of silver, gr. y^ gradually increased to gr. 3, in pill form. Never should be given with tannin or a vegetable extract ; an explosive compound may result. . The fused or solid form is used externally. The antidote for nitrate of silver is chloride of sodium (common salt) freely; it precipitates it in the insoluble chlo- ride of silver; also acts as an emetic. ESCI-IAROTICS OR CAUSTICS. 129 Dental Uses. — Nitrate of silver is employed in dental prac- tice for obtunding sensitive dentine, especially where the cause is mechanical abrasion, or from the fracture of a tooth, expos- ing the healthy and sensitive dentine, the stick form being em- ployed, or the end of a silver wire may be immersed in nitric acid and carefully applied. It is also a valuable application for ulcerated conditions of the mucous membrane of the mouth, also as a treatment for caries in deciduous teeth. Carbolic Acid^ CgH^O. Derivation. — Carbolic acid, phenylic alcohol or phenol, is obtained as an alcoholic product of the distillation of coal tar, between the temperatures of 338° and 370° F. Carbolic acid, though the universal name, is inappropriate. It does not be- long to the acid series (it will not turn blue litmus paper red), being neutral in its reaction. Properties. — Carbolic acid, when pure, is in the form of colorless or pinkish acicular (needle-like) crystals. It becomes an oily liquid at 95° F., or, if exposed to the air, the crystals readily absorb moisture and are thus liquefied. Five per cent, of water liquefies it; any further addition simply forms a mechanical mixture. It is freely soluble in alcohol, ether, chlo- roform, glycerine, and the essential oils. It has a strong aro- matic odor and taste, resembling creasote somewhat. Actions. — Carbolic acid in its pure state is escharotic; when diluted, it is a powerful antiseptic, germacide, rubefacient, and is a violent poison; internally, it is a sedative and carminative, allaying vomiting and gastric irritability. It resembles creasote closely in many of its medicinal prop- erties, but is probably more efficacious, and its odor is surely less objectionable. Dose, gr. y^, for relief of nausea, etc. Dental Uses. — Carbolic acid is a valuable agent in dental therapeutics, it being one of the best escharotics, styptics, anti- 130 DENTAL PATHOLOGY AND DENTAL MEDICINE. septics, sedatives, etc. It is used to obtund sensitive dentine, to relieve odontalgia, when caused by the exposure of the tooth pulp, by applying it to the exposed surface; it arrests putrefac- tive changes, is a valuable agent in the treatment of alveolar abscess; is also used to bathe cavities in the teeth, both for its obtunding effect upon the sensitive dentine and to destroy any low organisms that may be in the softened dentine. In a form known as phenol sodique, carbolic acid is very useful as a styptic for the treatment of superficial hemor- rhage after the extraction of teeth, and forms an excellent anti- septic mouth-wash. "Combined with glycerine (1 part to 12 of glycerine) it will stimulate the mucous secretion, and hence has been applied to the palate, in cases of deficiency of this secretion, to promote the suction of the upper dentures."* • Acetic Acid^ C^Kfi^. Derivation. — Acetic acid is produced from wood by de- structive distillation. Properties and Actions. — The purified acid contains about 28 per cent, of anhydrous acetic acid. The dikited acid, the only form employed internally, is composed of one part acetic acid to seven parts distilled water. It is a stimulant, astringent, diaphoretic, escharotic, etc. The strong acid, when applied to the skin, causes considerable redness and pain, which rapidly results in a blister (vesication). Dose. — Acetic acid, dilute, 3j-ij. Therapeutic Uses. — Acetic acid is sometimes employed in fevers, night sweats, hemorrhage of the lungs or stomach. Ex- ternally, the strong acid is used in the treatment of cancer, corns, warts, or fungous growths. The dilute acid is sometimes employed externally to gangrene, ulcers, and sprains or bruises. *Pi-of. Gorgas. ANTIZYMOTICS. 131 Dental Uses. — Acetic acid is sometimes applied to indolent ulcers of the month, and to fungus growths of gum or dental pulp ; for the latter the concentrated form is employed. Gorgas gives the following formula for indolent ulcers, cancrum oris, etc. : Acetic acid three fluid ounces to distilled water five fluid ounces; apply with camel's-hair brush. Trichloracetic Acid. Derivation. — Trichloracetic acid is formed from acetic acid, three atoms of the hydrogen of which is, in the new acid, re- placed by chlorine. It is one of a group of three acids, having similar properties; the difference in their composition is due to the proportion of chlorine they contain. The others referred to are monochloracetic and dichloracetic acids. Properties and Actions. — Trichloracetic acid is in the form of colorless, deliquescent crystals, having an agreeable odor, and is readily soluble in water and alcohol. Its concen- trated solutions are powerful caustics, while the weaker solu- tions make a good antiseptic. Therapeutic Uses. — As an antiseptic it is used in putrid and indolent wounds and erysipelas. Diluted with water to a 3 per cent, strength it is an effective stimulant and astringent. Dental Uses. — It is used in dental practice as an escha- rotic; 10 per cent, solution is often employed in the treatment of pyorrhoea alveolar is, acting, it is claimed, as a solvent on calculi upon the roots of teeth. A one per cent, solution is reconunened as a mouth-wash, owing to its astringent and stimulating qualities. ANTIZYMOTICS. Antizymotics are agents which arrest or prevent fermenta- tive processes; they are divided into antiseptics and disin- fectants. 132 DENTAL PATHOLOGY AND DENTAL MEDICINE. Antiseptics are those agents whicli prevent or retard septic decomposition, either by destroying the bacteria upon which putrefaction depends, or by arresting their development. The most important of this group are bichloride of mer- cury, peroxide of hydrogen, carbolic acid, (see Escharotics),. potassium permanganate, iodoform, phenal sodique, alcohol, eucalyptol, etc. Disinfectants are those agents which destroy the germs of infectious diseases. The principal members of this group are carbolic acid (see Escharotics), zinc chloride (see Tonics, Zinc), potassium per- manganate, iodine (see Irritants), aromatic sulphuric acid (see Tonics, Sulphuric Acid). Bichloride of Mercury^ HgCl2. Derivation. — Bichloride of mercury, mercuric chloride, or "corrosive sublimate," is obtained by distilling* a mixture of sodium chloride and mercuric sulphate; a double decomposition takes place, forming mercuric chloride and sodium sulphate. Properties. — Bichloride of mercury is in the form of col- orless crystalline masses. It is inodorous, fusible, soluble in 16 parts of water, 7 parts of alcohol and ether, and has an acrid, styptic taste. Actions. — Bichloride of mercury is one of the most active salts of mercury. It is one of the most efficient of all the anti- zymotics in the strfength of 1 part to 2000 parts of water. It is internally employed in chronic diarrhoea, dysentery, and syphilis. Dose, gr. Vsq-Vio i^ piU form. Antidotes to bichloride of mercury are albumin, wheat flour, milk, etc. ♦The double process of vaporization and condensation of the vapor. ANTIZYMOTICS. 133 Dental Uses. — For prophylactic treatment of the oral cavity, particularly of the teeth, bichloride of mercury, 1 to 10,000, is most effective. It should be carefully used, however, on account of its poisonous character. It is also used extensively in dental practice, in treatment of alveolar abscesses, and in diseases of the antrum of High- more, in a solution of 1 to 2000, to 1 to 5000. Peroxide of Hydrogen^ 112^^2- Derivation. — Peroxide of hydrogen is obtained by combin- ing an extra molecule of oxygen with hydrogen monoxide, H^O (water), the result being a water-like liquid, H2O2. "As when barium dioxide is dissolved in dilute hydrochloric acid : — BaO^+SHCl+H^O-BaCl^+H^O-fH^O^."* Properties. — Peroxide of hydrogen is in the form of a col- orless, transparent liquid, is inodorous, and almost tasteless. Actions. — Peroxide of hydrogen is one of the most efficient and at the same time the least harmful of all antiseptics and disinfectants. The second molecule of oxygen, spoken of above, is very loosely combined, and the mixture is always on a strain to break up into water and oxygen; for this reason it should be kept in a cool and dark place, and it is owing to this fact (that peroxide of hydrogen generates "ozone," O3) that pus and the bacteria of diseased surfaces, when treated with this agent, are at once destroyed. "As soon as ozone has accom- plished its cleansing effects upon the infected surface, it is readily transformed into ordinary oxygen, owing to its insta- bility." It is employed as an internal remedy in fevers, whoop- ing cough, bronchitis, consumption or phthisis, diphtheria, dys- pepsia, catarrh of the stomach, etc. LfOcally Employed. — Peroxide of hydrogen may be em- ployed for its antiseptic and pus-destroying properties in the *Leffmann's "Chemistry." 134 DENTAL PATHOLOGY AND DENTAL MEDICINE. treatment of abscesses, ulcers, carbuncles, wounds, both fresh and putrid, catarrh of the nose, hay fever, diphtheria, etc. It is also the base of most hair-bleaching solutions. Dose of peroxide of hydrogen, 3ss-ij. Dental Uses. — It is one of the most valuable remedies in dental therapeutics, being especially valuable as a cleansing agent, and is employed also in the treatment of alveolar abscesses, pyorrhoea alveolaris, inflammation and ulceration of the oral mucous membrane, fungous growths, etc. Pyrozone. Derivation. — ^Pyrozone solutions are aqueous or ethereal fluids, containing exact percentages of hydrogen peroxide. The solutions are prepared in two strengths, aqueous 3 per cent, solution, and ethereal 25 per cent, solution. Properties and Actions. — Pyrozone 3 per cent, solution is a rapidly acting, harmless antiseptic, which can be employed externally or internally without danger of toxic effects. It may be used in all cases where carbolic acid or other disinfect- ant is indicated. The 25 per cent, solution is a bleaching agent, and when applied to diseased parts acts as a powerful caustic, bringing about resolution in a short time. Therapeutic Uses. — The 3 per cent, solution is used in cer- tain forms of indigestion or dyspepsia, ulcers of the stomach, and gastritis; 25 per cent, solution is applied to ulcers, syphil- itic patches, pus-generating surfaces, and for chronic eczema. Dental Uses. — Pyrozone is used in the 3 per cent, solution as a mouth-wash; it is non-poisonous, and in cases where the micro-organisms of the mouth threaten septic invasion of the stomach, it forms a perfect gargle or spray. It completely de- stroys pus and mucous secretions, and renders the mouth aseptic. The 25 per cent, solution is, as has been indicated, employed principally as a bleaching agent, and is proving a most valuable drug for that purpose. antizymotics. 135 Peroxide of Sodium. Derivation. — Sodium peroxide is obtained by adding hydro- gen peroxide to an excess of caustic soda, 20 per cent, solution, which is then poured into alcohol. Properties and Actions. — Sodium peroxide is the chemical analogue of hydrogen peroxide, and is dispensed as a yellowish white powder, which is soluble in water, which action produces an increase in temperature and evolves a certain arflount of oxygen. It is a strong caustic alkaline, which properties it re- tains after the loss of part of its oxygen, becoming Na20, which in combination with water, is ordinary caustic soda. Dental Uses. — It is used in dental practice as a bleaching and sterilizing agent. It is claimed that sodium peroxide re- moves more completely than any other drug, the dental tubular contents; and it is further claimed that the normal translucency of the tooth is more fully restored. Permanganate of Potassium, KgMn^Og. Derivation. — Permanganate of potassium is prepared by fusing the black oxide of manganese with chlorate of potassium and caustic potassa. Properties. — It is in the form of dark purple crystals; it is very soluble in water, forming a beautiful lilac-colored solution ; inodorless, and has a sweetish, astringent taste. Actions. — Permanganate of potassium taken internally is a stimulant, and is given with benefit in dyspepsia; is a mild escharotic, and a powerful disinfectant and deodorizer. The solution is decomposed by organic matters, sulphides and sul- phites, yielding up its oxygen readily (on which property its use depends), and is coilverted into a colorless solution. . The most important uses for this agent are external, where it is employed as a deodorizer and disinfectant in abscesses, ulcers, cancers, caries of the bone, etc., in the form of a lotion and spray, while the powder may be sprinkled on gangrenous 136 DENTAL PATHOLOGY AND DENTAL MEDICINE. surfaces, acting as a local stimiilaiit as well as a deodorizer. Dose, for internal use, gr. ^-j. For external use, i^ to water, fSv-x. Dental Uses. — It is employed in dental practice in the treat- ment of foul abscess, in diseases of the antrum, necrisis of the maxillary bones, ulcers of the mouth attended with fetid dis- charges, offensive breath, etc. Iodoform^ CHI3. Derivation. — Iodoform is a preparation of iodine. It is "obtained by the action of chlorinated lime upon an alcoholic solution of iodide of potassium, heated at 104° F., the product being iodoform and iodate of lime, the iodoform being separated by boiling alcohol." Properties. — Iodoform is in the form of small yellow crys- tals, which are soft to the touch, of a sweetish taste; is volatile, and has a very unpleasant odor (which may be covered with oil of rose, etc.) ; is insoluble in water, but is soluble in alcohol, ether, chloroform, and the essential oils. Actions. — Iodoform is an efficient antiseptic, inhibiting and destroying the microbes of putrefaction and suppuration; it has also slight local anesthetic properties. Internally in small doses it is a tonic, alterative, anodyne, and antiseptic. In large doses it causes a form of intoxication, followed by convulsions, collapse, and death. Dose, gr. j-v, in pill form. . Dental Uses. — In dental practice iodoform is a valuable agent; it is an excellent antiseptic for the treatment of alveolar abscesses, putrescent pulps, especially when combined with oil of eucalyptus. Prof Peirce recommends iodoform ground with equal parts of oil of cloves and oil of eucalyptus, a portion of which may be introduced to the inflamed part on the point of a small broach. ANTIZV3L0T1CS. ±0 i Iodoform is also serviceable as a packing for the pockets of pyorrhoea alveolaris, and as a dressing or packing for wounds, where it may be used in the powdered form or in the form of a gauze wliich is prepared for the purpose. Aristol. Derivations. — Aristol is a preparation of iodine, and has gained a position in recent therapeutics as a perfect substitute for iodoform. It is a thymol iodide, and is ''produced by treating an aqueous solution of iodine in iodide of potassium with an aqueous solution of thymol in the presence of caustic potash." Properties. — Aristol is in the form of a reddish brown pow- der; is volatile, and has a slight aromatic odor, though when compared with iodoform we may say it is practically inodorous. The quantity of iodine contained in it is from 45 to 50 per cent. Aristol is insoluble in water and glycerine, slightly soluble in alcohol, but is readily soluble in ether, chloroform, collodion, and the fixed and ethereal oils. Actions. — Aristol is an efficient antiseptic; it is particularly applicable as a dressing for wounds, ulcerations, and abrasions of the skin and mucous membrane. It may be dusted over the wound, or applied in the form of aristol ointments (compounds of vaseline or cold cream) or in combination with collodion. All of these are excellent and easy of application. Its efficiency as an antiseptic and alterative is largely due to the fact that it slowly gives off its iodine, and it is also due to this fact that it does so decompose, when exposed to the light or undue heat, that it should be kept in a colored bottle or a closed box and in not too warm a place. If this is not done, the loss of iodine will be readily noticed by its grad- ually becoming paler in color. Dental Uses. — Aristol is a welcome addition to our cata- logue of therapeutic agents. I have found it an excellent agent 10 138 DENTAL PATHOLOGY AND DENTAL MEDICINE. for treating root-canals from which putrescent pulps have been removed and for alveolar abscesses. It can also be used advan- tageously in combination with root-filling materials; it may be used by mixing the powder with chloro-percha, or, where gutta- percha cones are to be used, the cone may be dipped in a solu- tion of aristol and chloroform and immediately carried to position. Dr. Kirk says of it in this connection: "I have made use of aristol in connection with root-filling materials by an- other method. A strong solution of aristol is made in the oil known to house-painters as 'Japan dryer,' sufiicient of the drug being added to make the liquid somewhat thinner than glycer- ine; into this is worked with a spatula freshly calcined oxide of zinc until the mass is like putty, in which condition it is to be worked into the root-canals. The mass becomes quite hard, and seems to fulfill admirably the requirements of a root-filling." Formalin. • Derivation. — The name formalin has been given to a 40 per cent, solution of chemically pure formaldehyde in water. Formaldehyde (CH2O), as is well known, is a gaseous body which is prepared by subjecting methyl-alcohol to oxidation. It is readily absorbed by water; for this reason it is put on the market in the form of an aqueous solution termed "forma- lin." It mixes with water in all proportions, making it easy, therefore, to prepare any dilution required. Properties and Actions. — Formalin can be used either in a gaseous or liquid form ; it is non-poisonous, of a peculiar, penetrating odor. When brought into contact with the animal skin, undiluted formalin exerts a kind of tanning effect, mak- ing the skin impermeable and finally brings about necrosis. The tissue is destroyed with suppuration or formation of a wound. Therapeutic Uses. — Formalin is an ideal germicide, disin- fectant, deodorant, and antizymotic, possessing the same germ- icidal power as corrosive sublimate, without its toxicity. It is ANTIZYMOTICS. 139 used in aseptic and antiseptic surgery, for inhalations, in oph- thalmic practice, in bacteriology, as a hardening and preserving medium, and in the recognization of the typhoid bacillus. Dental Uses. — It may be used in dentistry for destroying the nerves of teeth, and as an antiseptic agent. Gaultheria. Derivation. — Gaultheria is obtained from the leaves of the gaultherise procumbens (Ericaceae), a small plant common to North American woods. These leaves contain tannic acid, urson, arbutin, ericolin, a volatile oil, etc. Properties and Actions. — Gaultheria has an aromatic, bit- ter, and astringent taste. The volatile oil is composed princi- pally of methyl salicylate and gaultherilene, which produce pure salycilic acid. Therapeutic Uses. — The oil of gaultheria is antipyretic and antiseptic, and is used in wounds, and administered internally for auricular rheumatism. The spirit of gaultheria is used as a flavoring extract. Dental Uses. — Gaultheria, being one of the essential oils, is useful to the dentist for its antiseptic properties, either alone or combined with other medicines for the treatment of alveolar abscess and putrid root canals; it is also an ingredient of local anesthetic mixtures. Creasote. Derivation. — Creasote is one of the products of the distilla- tion of wood-tar, and consists principally of such phenols as phloral, creasol, methyl-creasol, and guaiacol. It can also be obtained from crude pyroligneous acid. That made from beech- wood, however, is the better form for medicinal use. Properties and Actions. — Creasote is a colorless, oily fluid, with an odor somewhat resembling carbolic acid, and has a burning taste. It is a stimulant, antiseptic, styptic, sedative. 140 DENTAL PATHOLOGY AND DENTAL MEDICINE. and rubefacient. In large closes it is a narcotic poison, causing death by coagulating the albumen of the blood, preventing its circulation through the arteries. It is used in small doses, gen- erally, for its astringent qualities. Therapeutic Uses. — Internally, creasote is administered for pulmonary consumption, chronic bronchitis, vomiting and gas- tric troubles, diarrhoea, diabetes, etc. Externally, applied to hemorrhages from wounds, etc., diseases of the skin, eruptions, ulcers, etc. Dental Uses. — Creasote has for many years been employed in dental practice for relieving odontalgia, as an obtundant, for alveolar abscess, ulcers of the mouth, etc. Its antiseptic powers render it valuable for offensive purulent discharges; and its styptic properties are sometimes taken advantage of in the treatment of hemorrhage after extraction of teeth. Naphtiiol. Derivation. — Naphthol is derived from naphthalene (C^qH^) which is a coal-tar product and in the form of white crystals, having a strong, unpleasant odor; soluble in alcohol, but not in water. This alcoholic solution is known as naphthol. Properties and Action. — There are two forms of .naphthol, a-naphthol and /S -naphthol; the latter, owing to its less irri- tating effects, is generally employed medicinally. It is a light- brown crystal, soluble in hot water. Therapeutic Uses. — Owing to its antiseptic properties it is used in parasitic diseases of the skin ; it is given internally, and applied externally as an ointment. Dental Uses. — ITydronaphthol, supposed to be a form of ,'3-naphthol, is most generally used in detal practice for treating canals and pulpless teeth, pericemental inflammation of septic jrigin, especially in early stages before pus has formed. Pro- fessor James Truman recommends a solution of 1 : 1000 of water for injection into pulp canals. It is also recommended as an AXTJZYMOTICS. 141 ingredient for a mouth- wash for diseased gums and mucous membrane. Campho-phenique, C^Hj^O. Derivation. — Campho-phenique is obtained from the chemi- cal union of carbolic acid and camjihor. It is prepared as fol- lows : Nine parts of carbolic acid to one part of alcohol are mixed with twenty-five parts camphor. The clear oily solution is the result. Properties and Actions. — Campho-phenique is a limpid, volatile fluid, having an aromatic taste and the odor of camphor. It is an antiseptic, a mild local anesthetic, and germicide; is non-irritant, non-poisonous; insoluble in water or glycerine, but will mix in all proportions with alcohol, ether or chloroform. Dental Uses. — As a dressing in the treatment of putrescent pulp-canals it has given quite satisfactory results. It has been employed hypodermically as a local anesthetic, causing no con- stitutional disturbance. It is also recommended for the relief of pain following the extraction of teeth, in which case it is introduced into the sockets upon pledgets of cotton. Cinnamon (Cassia Bark). Source. — The commercial cinnamon is the prepared bark of a tree of the natural order Lauraceae. The best varieties of this bark are obtained from Ceylon. It contains a volatile oil, an acid peculiar to itself — cinnamic acid — a trace of tannic acid, mucilage, etc. Properties and Actions. — Cinnamon is placed upon the market in the form of long, thin, cylindrical pieces, having a yellow-brown color, a fragrant odor, and a sweetish, aromatic, and mildly-astringent taste. It is more powerful as a local than as a general stimulant. Its medicinal virtues, however, reside in a volatile oil, oleum cinnamomi, or oil of cinnamon. 142 DENTAL PATHOLOGY AND DENTAL MEDICINE. Therapeutics. — Cinnamon is sometimes employed to allay nausea and vomiting, and in combination with chalk and with other astringents it is used for the treatment of diarrhoea. The oil of cinnamon is often employed to conceal the taste of other medicines, and is a strong local stimulant. Oil of Cassia. — Oil of cassia is prepared from the bud of the same order of tree, and the oil of cinnamon from the bark. The oil of cassia is preferred by many as an antiseptic for local treatment. Dental Uses. — Oil of cinnamon and oil of cassia are em- ployed by many as antiseptics in dental practice. In the treat- ment of putrescent root-canals the writer has secured very sat- isfactory results from both these drugs. Applied to exposed and inflamed dental pulps, they will give temporary relief, and have been recommended for the treatment of pyorrhoea alveo- laris, combined with iodoform. Dr. Black's "1, 2, 3 mixture" is composed of oil of cinnamon, 1 part; carbolic acid (crystals), 2 parts; oil of gaultheria, 3 parts. This is employed in the local treatment of pyorrhoea alveolaris, and for alveolar ab- scesses, etc. Electrozone. Derivation. — Electrozone is the product of sea- water speci- ally treated by electrolysis. It has been so named from the fact that it is manufactured with the aid of the electric current, and the oxidizing agent being ozone. The result of electrolysis thus performed is the formation of new compounds, consisting of the hypochlorites, hypobromites, etc., and, it is claimed, the substitution of free oxygen and peroxide of hydrogen for the air between the molecules of water. Properties and Actions. — It is a clear, colorless liquid, hav- ing an unpleasant, salty taste, and an odor resembling chlorine. It is a non-poisonous and efficient antiseptic, germicide, and disinfectant. CATHARTICS. 143 Therapeutic Uses. — It is much used for diphtheria, catarrh^ and fevers, and is applied to burns, scalds, and wounds of any nature. Dental Uses. — It is valuable to the dentist for its antiseptic and germicidal qualities, and is very efficacious in the treat- ment of acute pulpitis, giving almost instant relief. The writer has also found it very valuable in the treatment of root- canals, as a mouth- wash, and wherever a harmless germicide and deodorizer is desirable. CATHAETICS. Cathartics, or purgatives, are agents which hasten the intes- tinal evacuations; they comprise such substances as magnesia preparations (Epsom salts), senna, rlnibarb, fruits of various kinds, etc. Magnesia^ MgO. Derivation. — Magnesia, or magnesium oxide, is obtained by subjecting magnesium to a red heat in the open air, when it will burn with a bright light and produce MgO. Properties. — Magnesia is a very light, white powder, odor- less, has an earthy taste, is freely soluble in water — more so in cold water — and neutralizes acids. Actions. — Magnesia is an efficient aperient (mild purga- tive), is antacid — whence an excellent remedy for great acidity, of the stomach — and is the antidote for poisoning by mineral acids. When it is desirable to administer magnesia in large doses and for a considerable length of time, it may be given in connection with lemonade, which will render it more soluble, avoiding its accumulation in the bowels. Chief Preparations: — Sulphate of Magnesia, "Epsom salts," "salts." Dose, 3j-§j, in water, a popular purgative. 144 DENTAL PATHOLOGY AND DENTAL MEDICINE. Liq. Citrate of Magnesia (magnesium carbonate), citric acid, potassium bicarbonate, and water. Dose, 5iv-vj. Dose of Magnesia as an aperient, gr. x-3j. As an antacid, gr. 20(9j). Dental Uses. — The form of magnesia usually employed in dental practice is known as magnesium hydrate, or milJc of magnesia, and consists of precipitated magnesium hydrate held in suspension in water, and is employed for counteracting the injurious action of acid secretions, especially in cases of erosion. It is applied in the same way that lime-water or precipitated chalk is used for the purpose of bringing about an alkaline condition of the oral fluids, by neutralizing the excess of acids present. A teaspoonful of the preparation taken into the mouth and allowed to float about the teeth coats them with a slight alkaline film, which protects the tooth surface from the acid action for several hours. MISCELLANEOUS DEUGS. GLYCERm. Derivation. — Glycerin is a production of the saponification of fijied oils and fats; it also contains a small percentage of water. Properties and Actions. — It is a colorless, syrupy liquid, having a sweet taste but no odor; soluble in water or alcohol. It is a solvent, preservative, emollient, and nutrient. Therapeutic Uses. — It is used to dissolve iodine, iodide of potassium, borax, tannic acid, creasote, carbolic acid, etc. It is much used in poultices and for roughness of the skin, as one of the ingredients for dressings for wounds and ulcers, erysipelas, and small-pox (to prevent pitting). Glycerin is used in cases of earache and deafness. It should be mixed with a little water before applying to abraded or cut surfaces to prevent smarting. Dental Uses. — Glycerin is much used in dotal practice as a solvent and emollient. It is used in the treatment of diseases M ISCMLI.AM^ors DKl'CiS. 145 of the mucous membrane of the mouth, such as ulcers, stoma- titis, alveolar abscess, etc. Combined with lime-water, rose- water, gum tragacanth, etc., it forms ointments and emollients. Combined with atropine, acetate of lead, morphine, etc., it is used as an anodyne and emollient. Collodion. Derivations. — Collodion is a solution of pyroxylin, stronger ether, and alcohol, in the proportion of 4, 70, and 26 respec- tively. Pyroxylin, or common gun-cotton, is a mixture of nitric and sulphuric acids added to cotton freed from im- purities. Properties and Actions. — Collodion is a colorless, inflam- mable liquid, of the consistency of syrup, with an ethereal odor. It is used to protect abraded or cut surfaces from the air, by means of the film which it forms. Owing to its astringent ten- dencies it draws together and holds in apposition divided parts. Therapeutic Uses. — It is applied to ulcers, abraded surfaces, fissures, and is also used in skin diseases and erysipelas. Dental Uses. — Combined with carbolic acid it is applied for odontalgia. With iron, etc., it forms a styptic preparation. When a number of layers are applied, it will sometimes prevent an alveolar abscess from discharging on the face, causing it to open in the mouth. It is useful in the dental laboratory for coating plaster models, protecting the surface. Should it be- come too thick, dilute with a solution of ether and alcohol, 3 to 1. Sandaraoh. Derivation. — Sandarach is derived from an evergreen tree common to Northern Africa. Properties and Actions. — Sandarach gum is in the form of small, irregular drops, of a light yellow color, occasionally brown; brittle, and slightly transparent. It has an agreeable 146 DENTAL PATHOLOGY AND DENTAL MEDICINE. odor and a resinous, acrid taste. It is inflammable, and when melted by heat throws out a strong balsam odor. It dissolves readily in alcohol or ether. Dental Uses. — The alcoholic solution of sandarach is much used in dental practice as a varnish for coating plastic fillings, etc.; and applied on cotton as a temporary stopping, and for a coating for cotton used for separating purposes. ANTACIDS. Bicarbonate of Soda, 2NaIIC03. Sodium bicarbonate is a white powder, having a mildly aUva- line, cooling taste. It is soluble in water, insoluble in alcohol. Alkaline in reaction. Dental Uses. — Sodium bicarbonate is used in dental prac- tice to counteract the actions of acids, and is sometimes em- ployed as an antacid ingredient of dentifrices, etc. Borax, Na22B202. Borax, or sodium borate, is a white powder having an alka- line taste and reaction. It is both alkaline and antiseptic and may be used in a saturated solution where these qualities are desired. Dental Uses. — It is sometimes employed in mouth-washes, particularly in the treatment of stomatitis or thrush. The latter trouble occurring usually in the mouths of infants, a saturated solution of glycerin has been suggested for the treat- ment of same. Borax is also useful in blow-pipe analysis, as a flux in soldering metals, in solution for hardening plaster casts, etc. Lime Water. A saturated solution of calcium hydrate in water. It is a colorless, nearly odorless liquid, alkaline in reaction. Lime ANTACIDS. 147 water is readily prepared by treating freshly slaked lime with distilled water. Dental Uses. — ^Lime water may be used freely as an antacid mouth-wash and gargle. It may also be used to correct acidity of the stomach, and is frequently added to the food of infants for this purpose. Magnesia (see Cathartics). Prepared Chalk^ CaCOg. This substance is a form of calcium carbonate. It is a white powder, sometimes moulded into small blocks or cones, almost tasteless, very slightly soluble in water and insoluble in alcohol; it is antacid, absorbent and astringent. It is prepared by freeing chalk from impurities and gritty substances by elutriation (e-lu-tre-a'shun) . Dental Uses. — The insolubility and antacid property of prepared chalk gives it special value as a basis for tooth powders and as a packing between teeth over night where there is a strong tendency to acidity. It is employed by some dentists to Telieve sensative dentine in cavities of decay or erosion. In such cases it is employed for several days before operating. It is used in the laboratory for polishing purposes. APPENDIX. EMERGENCIES. Preliminary Remarks. Nothing, of course, can take the place of the advice and service of an experienced physician in time of emergencies; but the physician is not always at hand, and accidents of various kinds may occur in the dental office, or patients in distress present themselves to the dental practitioner for im- mediate relief; or some one may be burned, cut, poisoned, or suffocated, where, if we possess presence of mind and sufficint knowledge, it may be our privilege to save an endangered life. It is, therefore, expedient that the dental student should have a more thorough knowledge of what to do in case of such emer- gencies; it is for that purpose that this chapter of practical suggestions is prepared. Apoplexy is the rupturing of a blood-vessel in the brain. The symptoms are stupor, heavy snoring breathing, slow pulse, flushed face, followed by paralysis usually of one side, this being marked by the drawing up of one side of the face. Treatment. — Loosen clothing about the neck, make cold ap- plications to the head, and keep the patient in a sitting posture until the physician arrives. Burns or Scalds. — Not infrequently does some one's cloth- ing take fire, usually that of women, on account of the charac- ter of their clothing. The first thing to do in time of such an accident is to have the patient lie down, but if she loses her presence of mind and will not obey instructions, she must be quickly placed upon the floor or ground and then covered or enveloped at once with the first article you seize that will ex- 148 APPEADJX. 149 elude the air and smother the flame — a breadth of carpet, rug, blaiilvet, or coat will serve the purpose. After the fire is extinguished, or after an extensive scald, if there is m.uch of a burn or blister, the clothing-, as much as need be removed, should be carefidly clipped away, so as not to break the blisters that may have formed. These may be punc- tured at one edge and their contents discharged, when the outer skin will fall back in place. Then a dressing of pure sweet oil or castor oil should be carefully applied on strips of soft linen. When the skin is destroyed, the air may be excluded by apply- ing at once any of the following : sweet oil, linseed oil, collodion, vaseline, etc. Dr. Charles Dulles, in his manual on accidents and emergencies, says : "In case of a person severely and ex- tensively burned, the entire body may be immersed in a bath, which shall be kept, as long as necessary, at a temperature of 100°. Where the shock of a burn is great some stimulant should be given, and laudanum, in twenty-droi:) doses to an adult, and half as much to a child, to allay the suffering." For Slight Burns or Scalds, an excellent dressing is to quickly sprinkle the parts with bicarbonate of soda and cover same with wet cloth, or they may be painted with white lead, or covered with the white of an egg or carron oil (equal parts of linseed oil and lime water) — in fact, anything that will ex- clude the air and prevent friction, and will not prevent after- examination, may be used. Aristol ointment (aristol in cold cream or vaseline) is also being used with good results, while for small burns on the hand, arm, leg, etc., immerse instantly in cold water, and let it remain for some length of time. Burns with Acids or Caustic Alkalies, such as soap lye, should be deluged with water, and followed by an application of bicarbonate of soda for the former and vinegar for the latter, to be followed by an application of oil. Catalepsy in appearance somewhat resembles death. The patient becomes unconscious, the muscles rigid, and the skin 150 APPENDIX. pallid. In itself it is by no means dangerous, and it affords time enough to summon a doctor, which is the only sensible thing to do under these circumstances. Choking is usually caused by the lodgment of some foreign substance in the trachea or oesophagus. When the body is lodged in the trachea, there is great irritation and coughing, though it does not materially interfere with deglutition. While, on the other hand, when the oesophagus is closed, it is usually impossible to swallow, and there is little or no coughing. Treatment. — Hold the head low and slap the back quite forc- ibly. Blow into the ear, which will excite a reflex action that will aid the patient in expelling the foreign body. The re- moval of pins, needles, splinters, fish bones, etc., from the throat is usually an extremely delicate operation. They should be grasped with a small pair of forceps or tweezers, or a blunt pair of scissors may be used for the same purpose. Convulsions are usually caused by some irritation of the digestive apparatus, or hy some interference in the eruption of the teeth. Treatment. — When the physician's coming is delayed, the child should be placed in a hot bath; the head at the same time should be kept cool by cold applications. This should be con- tinued for about ten minutes, when the child should be wrapped in warm blankets and put to bed. If there should he one or more teeth endeavoring to erupt at this time, the gums should, he freely lanced. Dislocations can be easily detected. There is always de- formity, pain, and stiffness of the joint affected. Dislocation of the lowerjaw, with treatment for same, is fully treated upon pages 62 and 63. Dislocation of the fingers can easily be corrected by strong pulling and at the same time pressing the parts into place, where they should be retained for several days by a splint and bandage. Dislocations of other joints had better be left for the sur- geon's hands. "The risk of doing injury by injudicious efforts APPENDIX. 151 to set a joint is greater than that of waiting until a surgeon can be summoned." The patient, however, should be placed in the most comfortable position and hot fomentations should be applied. Drowning. — It is important to remember that the body as a whole, is a very little lighter than water; therefore, a person who is in danger of drowning should lie flat on the back and keep the entire body, with the exception of the mouth and nose, under water. The arms should be stretched at full length above the head, and the lungs should be kept filled with air as much of the time as possible. This would very materially aid both the one in danger and the rescuing party. Resuscitation. — Avoid delay. Do not wait to carry the patient to a house or hospital, but treat him on the spot. "Re- member that the patient is suffering from two things, want of air, or oxygen, and loss of heat from the body." The first thing to do, then, is to free the body from any clothing that may in- terfere with respiration — that is, about the neck, chest, and waist. If natural breathing has ceased, artificial respiration should be commenced as soon as possible. First, hastily make a roll from clothing, blanlvets, or anything that may be at hand, place the patient over this, face doivnward, allowing his fore- head to rest upon one hand to keep the mouth and nose clear of the ground. Place the hands, well spread, upon the patient's back, over the stomach and base of thorax. Then, with a for- ward motion, throw all the weight upon them that the age and sex of the patient will justify. Repeat this three or four times, which will cause the water and mucous to run out of the mouth, throat and trachea. (See Fig. 29.) Wrap a handkerchief around the forefinger and pass it into the mouth and remove any mucus that may remain. Turn the patient on his back, grasp the tongue and draw it forward and down onto the chin; lay a strip of the handkerchief or other material across the tongn.e and pass the ends behind the neck and tie, or have some 152 APPENDIX. APPENDIX. 153 one to hold the tongrie to keep it from falling back and closing the throat. Then begin artificial respiration. Howard's Method. — The patient is placed upon his back, his arms extended backward and outward, where they should be held by an assistant. A roll of something (clothing, a folded blanket, coat, or stick of wood, if nothing better is at hand) is then placed under the false ribs so as to throw them prominently forward. The operator should then kneel astride the patient's abdomen, placing both hands so that the fingers will press into the intercostal spaces on each side, and the base of the thumb rest upon the anterior margin of the false ribs. The operator should then place his elbows firmly against his sides, and throw himself forward, bringing his weight to bear upon the patient's false ribs, forcing them inward and upward toward the dia- phragm, then suddenly let go and return to the erect position. Repeat these movements ten to twelve times a minute until natural breathing begins, which may gradually take the place of the artificial. Fig. 30 illustrates this method. Sylvester's Method. — After the patient has been placed upon his back, with folded clothing under his shoulders, the operator should kneel behind his head and go through the following manipulations : — First, to induce inspiration : Grasp both arms just below the elbows and swing them around horizontally until they nearly meet above the head, with the back of the hands or elbows touching the ground; hold them there for three or four seconds. This draws the ribs up so as to expand the chest and allows the air to enter the lungs. (See Fig. 31.) The second movement is to induce expiration. Bend the arms at the elbows, and carry them down so that they rest upon either side of the chest. Bring the weight of your body upon them, pressing forcibly and steadily, which pressure, if con- tinued for a few seconds, will force the air out of the lungs. 11 154 APPENDIX. APPENDIX. 155 (See Fig. 32.) These movements should be continued alter- nately twelve to fifteen times a minute. When natural hreathing is attempted, it may be stimulated by applying smelling salts or anmaonia to the nose, or by slap- ping the chest. When the patient is able to swallow, some stimulant should be given every few minutes until the danger- point is passed — such as a teaspoonful of whisky or brandy, or double the quantity of hot water. After the patient is resus- citated he should be wrapped in warm blankets and carefully carried, with the head low, to a warm bed. Epileptic Fits are characterized by sudden loss of conscious- ness and power of co-ordination of motion; there is a rigidity of motion which is followed by violent convulsions of short duration, usually accompanied by more or less foaming at the mouth. There is also a peculiar cry that accompanies these attacks, caused by laryngeal spasms. Treatment. — There should be no struggling with the patient, but an effort should be made to regulate the movements so that the patient will not do himself any harm. A folded napkin or towel or a soft piece of wood should be placed between the teeth to prevent biting the tongue. As soon as the convulsions are passed, the patient should be allowed to rest quietly in bed for some time. Dr. Dulles says: "It would be a good plan if every one who is subject to epileptic attacks had his or her name and address placed inside the coat or in some place where it could be seen at once when the clothing is loosened to give relief, as is almost invariably done when such attacks occur. Epileptics should not, except where it is absolutely unavoidable, go about alone, or go into crowded places. They have no right, on their own account and for the sake of others, to incur risks involved in such conduct, except under stress of necessity." Exhaustion, Heat. — This is not a serious illness. It is usually caused by physical overwork in hot and badly ventilated rooms or in the heat of summer, — the latter is apt to be con- founded with heat or sunstroke. In heat exhaustion, however, 156 APPENDIX. APPENDIX. 0* Hi > «2 158 APPENDIX. there is a cool, moist skin, while in sunstroke the bodily tem- perature is raised and the skin is quite dry. Treatment of heat stroke is very simple. The patient should have complete rest, plenty of fresh air, and a mild stimulant — hot soup, milk, tea, or coffee, or a small dose (one or two tea- spoonfuls) of wine or brandy. Fainting is caused by the cutting off of the supply of blood to the brain, which is due to a temporary weakening of the heart's action. Treatment. — If, for any reason, the patient does not fall to the floor or couch so as to bring the head low, the body should be placed in such a position. This is to aid the heart in sending the blood to the brain, and if the head is placed a little lower than the body, the force if gravity will aid very much in sending the blood where it is needed. At the same time the clothing should be lossened and plenty of fresh air admitted. Cold water may be sprinkled upon the face, and ammonia or smelling salts applied to the nose tend to excite the nerves of sensation and rouse the heart to renewed activity. Fractures. — Fractured bones may be recognized by the de- formity and abnormal mobility of the parts affected. It is also usually accompanied by crepitus, — a clicking or grating sensation at the point of fracture. The treatment of fractures should not be attempted by any one who has not surgical training, and as there is no great haste necessary, an effort should be made to simply place the patient in as comfortable a position as possible until the physician ar- rives. The following notes and illustration (Fig. 33) are taken, with permission of the author, from Dr. G. R. Butler's "Emer- gency Notes" : — "If patient must he moved^ or travel some distance, apply temporary splints or dressings to prevent further injury from movement. APPENDIX. 159 Ed O P5 C3 . H O a H CO CO 160 APPENDIX. "In city or country one of the following list of materials may usually be found, and, by the aid of a little ingenuity, utilized for temporary dressings : — ''^For splints — Cigar boxes, pasteboard (boxes, book-covers), folded newspapers, shingles, barrel-staves, umbrellas, walking- sticks, rulers, paper-cutters, branches, twigs, straw, fence-pal- ings, spoons, tongs. "For padding — Cotton, flannel, towels, flax, jute, oakum, hay, moss, pieces of blanket, coat-sleeves or stockings stuffed with grass, hay, straw, or leaves. "For bandages — Handkerchiefs, stockings, garters, suspend- ers, sheets, blankets, and patient's clothing torn into strips. "The temporary treatment of the following special fractures should be studied and personally practised. Some of these im- provised splints and their application are shown in Fig. 33. ''Jaiv-hone — Four-tailed bandage. "Collar-hone — Broad bandage around chest and a^jm of in- jured side. Broad arm-sling. "Upper arm-hone — Two splints. ^Narrow arm-sling. "Foreariyi and wrist hone — One splint reaching to base of fingers. Broad arm-sling. "Rihs — Broad bandage around chest, applied during expira- tion — i. e., chest emptied of air. "Thigh-hone — Preferably a long posterior (back) splint reaching from waist to heel. If this can not be secured, simply tie limbs together. "Leg and anJde-hones — Internal (inside) splint, or tie limbs together." (See Fig. 33 for illustrations.) Freezing of the ears, nose, hands, or feet sometimes takes place in such a deceptive manner that much damage is done before it is recognized, for one may go sometimes with a part of the body frozen and not be aware of it, on account of the absence of sensation in the part, which is due to the freezing of the nerves. APPENDIX. 161 Treatment. — Warmth and circulation is the first demand, and this should be restored gradually until normal (98° Fahren- heit). This is best accomplished by applying snow or cold water to the part, to which gradually add warm water; gentle friction, too, is found beneficial. The after efi^ects, if serious, should have similar treatment to that of a burn. If the whole body or a large part of it is frozen, after tiie normal tempera- ture is restored the patient should be wrapped in warm blankets and given some internal stimulant, as tea or coffee, until the physician arrives. Hemorrhage. — There is no accident where a little accurate knowledge and a level head is of more value than in case of hemorrhage, whether it be from some external wound or from the rupture of a blood-vessel internally. Hemorrhage may occur from three sources, the arteries, veins, or capillaries; and its source can usually be determined by the color and manner in which the blood flows. Arterial : Hemorrhage from an artery is very dangerous, and life is often quickly lost; here it is that knowledge, judgment, and coolness is called for. The blood from an artery is bright red and flows' in jets, each jet or spurt corresponding to the beating of the heart. Venous or Capillary Hemorrhage is marked by the slow, steady flow of blood, it being darker than the arterial blood. Treatment. — The first thing to do in all cases of hemorrhage is to elevate the bleeding part, whenever possible, above the level of the heart. If in the hand or arm, raise above the head. In this position the blood has to travel up hill, and therefore reaches the wound with less force, which means slower escape of blood, and a greater likelihood of forming a clot at the mouth of the wound. Cold water or ice applied to the parts assists, especially in wounds of small arteries, by contracting the ves- sels. Styptics should be applied to contract the bleeding sur- 162 APPENDIX. face* and to aid in forming a clot. Probably the best remedies for this purpose are tannic acid, subsulphate of iron, or a mix- ture of vinegar and water, about one part of the former to four of the latter. Pressure on the artery at the wounded point or above the wound is a very simple expedient and will, in nearly all cases, prove of very great value in controlling the flow of blood until more permanent means can be employed. Several methods follow: Pressure with the fingers is made by placing one finger just above and one below the wound, and crowding the edges to- gether firmly. Pressure by compress and bandage consists of making a com- press of some soft material, such as muslin, linen, cheese cloth, etc., folded into suitable shape and bound securely upon the wound with a bandage. Pressure above the wound may be made by the finger, or when the wound is in a limb a tourniquet may be 'employed, which is readily made by tying a handkerchief around the limb loosely, with secure knots, then pass a pencil or knife through the handkerchief and twist in such a manner as to tighthen it sufficiently to stop the bleeding. This may be con- tinued until a surgeon has ligated the artery, which, if neces- sary, should be as soon as possible. Hemorrhage from the Nose is not infrequent and is usually not dangerous. It is generally due to the rupture of some of the capillaries of the lining membrane of the nose. But there are times when the bleeding is due to the rupture of a small artery, possibly from ulceration, when it is so profuse as to threaten life. In some cases, which are very rare, medical aid should be summoned at once. Treatment. — Have the patient to sit upright, and to hold the hands above the head, at least the one on the bleeding side. *See page 126. APPENDIX. 163 Take a towel and wring out of ice water or place in it finely cracked ice, and wrap it around the neck. If bleeding con- tinues, have patient snuff up from the hand or inject into the nostrils, with a small syringe, ice water and alum, a teaspoon- ful of alum to a half -glass of water. Vinegar, too, used in the same manner, will usually stop the flow of blood. But if these means should fail. Dr. Butler's plan will be found very good. He says: "Take a piece of cotton wool as large as the first joint of the thumb, tie a thread around its middle, soak it in alum water, or, if that is not at hand, oil it with sweet oil or vaseline and plug the nostril. This is best done by pushing the cotton with a screwing or twisting motion until firmly lodged. The thread serves to draw it out when required." Hemorrhage from the Gums can usually be controlled by syringing the mouth or sockets (if teeth have been extracted) with warm water to remove clots, then rinse the mouth freely with ice water and alum. If this should fail, some good styptic should be applied. (See page 69, "Hemorrhage after Extrac- tion.") Hemorrhage from the Stomach may be caused by inflam- mation, cancers, corrosive poisons, etc., or may occur without any apparent cause. It is, however, not a very frequent occur- rence. The blood in such cases, when vomited, is usually of a dark brown color, resembling coffee grounds, unless it has very recently and suddenly escaped into the stomach, when it is of a bright red color. Bleeding from the stomach should not be mistaken for bleeding from the lungs. It is therefore impor- tant to remember these facts : that blood from the stomach is usually of a dark brown color and is vomited and not frothy, while blood from the lungs is of a 'bright red color and is frothy, also that it is coughed up, not vomited. Treatment. — Hest in bed should be insisted upon. Keep the patient calm, as excitement increases the heart's action and the amount of blood; for the same reason stimulants should not be administered. The patient should be given small pieces of ice 164 APPENDIX. to swallow, and teaspoonful doses of vinegar may be given every ten minutes. Also ice-cold cloths may be placed over the stomach. PIemorrhage from the Lungs is usually caused by consump- tion and is rarely if ever fatal, except sometimes in the last stages of the disease. It is, therefore, not necessary to appre- hend immediate death, as is so often done. Treatment. — The best treatment to pursue until a physician arrives is to place the patient in a reclining position, but not with the head low, give small lumps of ice to be swallowed, and let him eat a teaspoonful of salt with the same quantity of vinegar. Salt absorbs water from the blood, and thus tends to relieve hemorrhage by thickening the blood. Also, if patient is not too weak, cloths wrung out of ice water may be applied to the chest and neck. Intoxication is usually caused by an excessive use of alco- holic beverages. It sometimes resembles apoplexy? and great care should be taken in determining the disease, as this mistake has been made with very embarrassing results. It should be remembered that in drunkenness there is a helplessness on both sides alike, but no paralysis; that there is usually some sensa- tion displayed by touching the eyeball, and that the patient can be aroused from the stupor; also, that the odor of liquor can be detected upon the breath, though this might be the case in apoplexy. Treatment. — A teaspoonful of aromatic spirits of ammonia in a half or two-thirds of a glass of water is a useful corrective and stimulant. If this is not at hand, a large draught of vine- gar often does much toward sobering an intoxicated person. In an extreme case, where respiration has ceased, or where there is evidence of collapse, artificial respiration should be resorted to, heat should be applied to the body, and copious draughts of hot coffee should be administered. Nausea, if caused by slight indigestion, can usually be cor- rected by taking a teaspoonful of baking soda and the juice of APPENDIX. 165 one lemon in a half of a glass of water; stir and drink while foaming-. Or take a teaspoonfnl of aromatic spirits of ammonia in a third of a glass of water. If the nausea is due to some- thing objectionable to the stomach, the soda and water will usually give relief by causing vomiting. Poisons. — The old maxim, ''an ounce of prevention is better than a pound of cure." is surely applicable to the subject of poisons. In the first place, all dangerous articles should be kept out of the way of chiA-ven; then, all bottles, etc., contain- ing anything of a toxic nature should be distinctly marked "poison." A very good plan is to have such bottles marked by a ball and chain, which may be procured at the drug store; this will give warning in the dark as well as in the light. When it is discovered that a poison has been swallowed, some one should be dispatched for a physician at once; meanwhile, treatment must be directed toward getting rid of the poison before it takes effect. First admi)uster a, prompt emetic. Some poisons, by their irritating effect, naturally produce vomiting, so that with a little encouragement the stomach will be thoroughly evacuated. Where this is not the case, the emetic will provoke expulsion of the matter. A very good emetic for such an emergency is luke- warm water in quantity, or a tablespoonful of mustard or salt to a pint of warm water. As this is no occasion for fastidiousness, any water that is at hand may be used ; if soapy, and the hands have been washed in it, use it, as by its very repulsiveness it may act more quickly than anything else; the patient should be urged to drink freely until he can contain no more, and be made to vomit over and over again. This sometimes leaves the patient much depressed in body, and mind, showing signs of collapse. In such a case, some mild stimulant may be given; hot tea is probably one of the best, as it is also a chemical antidote to many poisons. Strong, hot coffee is also good. To either of these a teaspoonful of brandy may be added. The patient will, of course, be in bed, and it 166 APPENDIX. should not be forgotten that warm coverings are indispensable. Hot bricks and hot-water bags or bottles, may be brought into requisition. Again, where it is known that poison has been taken, and especially if it is one of the more active and corro- sive, an antidote to counteract the action of the poison should be administered before or after the emetic. The following list of the more common poisons, with their antidotes, etc, will be useful for ready reference. SPECIAL POISONS AND READY ANTIDOTES. Poison. Acids — Sulphuric, Nitric, Aco- tic. Oxalic, Muriatic, or Hy- drochloric, Alkalies — Potash, Lye, Soft Soap, Strong Ammonia or Hartshorn, Arsenic, Carbolic Acid, -■ Chloral, Chloroform, Ether, etc., Iodine, Lead — Sugar of Lead { Mercury — Bichloride of Mer- cury or "Corrosive Subli- mate," Opium — MorpDine, Laudanum, Paregoric, Phosphorus, Prussic Acid, C I Silver — Nitrate of Silver, j- "Lunar Caustic," | Strychnine | Treatment. Give an alkali, such as powdered chalk, plaster, lime-water, as much as patient can swallow; or lime scraped from the plaster or white-washed wall, stirred in a cup of water. A tablespoonful of strong soapsuds, etc. Give an acid — vinegar, lemon-juice, sour Cider, etc. Acids and alkalies neutralize each other — that is, combine to form harmless salts. Milk or raw eggs, or flour and water, or lime-water and oil, and after patient has vomited freely, follow with a dose of castor oil. There is no chemical antidote, but the stomich should be protected and vomiting encouraged by giving mucilaginous drinks, flour and water, and oil freely — olive, lin- seed, or castor. Treatment same as opium. Loosen clothing; sprinkle cold water on the face; suspend the patient by the legs; artificial respiration, as for drowning. Starch and water; boiled or baked potatoes. Epsom salts; after vomiting freely, give dose of oil. Albumen, uncooked white of eggs, wheat flour, milk, etc. Induce vomiting first. There is no chemi- cal antidote, but strong coffee, pain, mo- tion, counteract its effect. In extreme cases, in addition to above treatment, cold water should be dashed on the face and chest, and artificial respiration and the battery resorted to. Provoke vomiting. Teaspoonful doses of turpentine, mixed with magnesia; but no oil, it favors the action of phosphorus. Induce vomiting first, and give teaspoonful of ammonia in water. Large teaspoonful or salt in a glass of water ; vomiting. Induce vomiting first; give a purgative; secure absolute quiet in a dark room. APPENDIX. 167 There are other poisons, such as Alcohol, Aconite, Bella- donna, etc., which need not be classified here, as vomiting thoroughly, followed by a mild stimulant and rest, is all that is needed. Poisonous Bites. — By this we mean bites of rabid or ven- omous animals and the stings of insects. Snake Bites. — Tie a cord, or a handkerchief twisted into a cord, tightly around the part just above the wound. Enlarge the wound by making a cross cut through the center of the bite with a pen knife. This will encourage bleeding, and will ex- pose the wound more thoroughly for the later steps in treat- ment, which are as follows: Draw the poison from the wound by means of suction with the mouth, unless the mouth be sore, or by taking a wide-mouthed bottle, and after saturating a piece of cotton or paper with alcohol or benzine, set it on fire and dip it into the bottle. As soon as the flames begin to die out, quickly invert the bottle over the wound and press tightly against the skin to prevent the admission of air. This will ex- tract the venom and blood from the exposed vessels. Then heat a knitting needle, a piece of wire, or small blade of a knife to a white heat, and thrust it into the wound. At the same time large doses of whisky or brandy should be given and the patient kept under the influence of the stimulant until medical aid can be secured. Some, however, prefer to use aromatic spirits of ammonia instead of whisky, one drachm to a wineglassful of water. Mad Dog Bites. — There are some physicians who claim that there is no such disease as hydrophobia; one author puts it in this way: "So-called hydrophobia exists exactly in proportion to the common belief in it," that is to say, the trouble is alto- gether mental. There is no doubt but that a great many deaths have been caused by fright and anxiety, but that all cases are spurious we are not prepared to believe, and think that prompt and heroic treatment should always be given. 168 APPENDIX. As dogs are, with many i^ersons, daily companions, it is im- portant to know the various symptoms of madness. The fol- lowing is a resume of the instructions issued by the Council of Hygiene, of Bordeaux. Signs of Madness ix Dogs. — "1. A short time after the dis- ease has been contracted, the dog becomes agitated and restless, and turns continually in his kennel. If unchained, he roams about aimlessly; he seems to be seeking something; then stands motionless, as if waiting; he starts, snaps at the air, as if catching a fly, and dashes himself, barking and howling, against the wall. The voice of his master recalls him and he obeys, but slowly, with hesitation and seeming regret. "2. He does not try to bite, is gentle, even affectionate, and eats and drinks ; but gnaws his litter, the ends of the curtains, the padding of cushions, bed-coverlids, carpets, and anything which happens to be in his reach. "3. From the movement of his paws along the ^des of his open mouth, one might suppose him trying to free his throat of a bone. "4. His voice is changed so markedly that it is impossible to overlook it. "5. He becomes surly, and begins to fight with other dogs." The symptoms, however, vary in different cases, and a change in the habits or manner of a pet dog should always be looked on with suspicion, and the animal should be chained for a while. The probability of hydrophobia being communicated to per- sons bitten by a mad dog varies with the location of the bite. If it be in a part unprotected by clothing, inoculation is almost certain ;• in other parts, the chances depend on the thickness of the clothing, which wipes the virus from the teeth. Treatment. — The treatment in case of mad dog bite must be altogether preventive, as after the specific symptoms manifest themselves the only thing to do is to keep the patient quiet by the administration of hypnotics, until death ensues. But this, APPENDIX. 160 of course, belongs to the physician. When one is bitten by a rabid dog, the same course should be pursued as directed for snake bite, excepting the stimulants. Then start at once for a hospital, where the patient can receive Pasteur's treatment 'by inoculation. Bites and Stings of Insects. — Despite the current belief that the bite of a tarantula, centipede, and other insects are dangerous to life, experience proves that they are in nearly all cases comparatively harmless, causing only temporary pain and annoyance. Treatment. — They may be treated with cold, wet applications; if nothing better is at hand, wet earth is good. The application of a few drops of hartshorn at the point where the sting entered will also give relief. It sometimes happens that a wasp or bee is swallowed in taking a drink of water hurriedly in the dark. In such cases the fauces swell rapidly from the moment the sting enters the throat, which places the patient in danger of suffocation. This should be treated by the free use of a gargle of hot water and salt, pending the physician's arrival. Sea-Sickness. — Sickness occasioned by the motion of a vessel at sea is often most distressing. The most efficient pre- ventive or treatment is to take a seat near the center of the vessel (if inclined to keep up) and, as the ship descends, take a full breath; wear a wide firm belt around the stomach, eat lightly, plainly and often; if the stomach is much disturbed, take the juice of one lemon in half a glass of water, with one tea spoonful of baking soda; stir and drink while foaming. Sprains. — A sprain is a sudden overstretching and tearing of the ligaments which enter into the formation of a joint, as w^ell as the tendons and muscles about the joint. Treatment. — The joint should be soaked in water as hot as the patient can bear for twenty minutes or more, then rub gently with cosmoline, and apply a snugly fitting, but not tight, flannel bandage, and give the part as near perfect rest as possible. 13 170 APPENDIX. ' Starvation. — When a person is found exhausted from starv- ation, he should be placed in a comfortable position and given stimulating, fluid food. Warm milk, soup, and hot coffee are among the best, given a little at a time, but often. Strangulation. — In cases of strangulation — ^that is, com- pression of the windpipe from the outside, as in hanging, etc.— the treatment to be pursued is to remove the pressure at once, and re-establish the respiration, as in drowning. Suffocation. — Suffocation from foul air, noxious gases, etc., is caused by a poisonous gas known as carbonic acid. When it is desirable to enter a cellar, well, mine, etc., where there is a suspicion of foul air, a thorough examination should be made. Man can not live in an atmosphere where a candle will not burn, animal life and flame being both supported by oxygen. The best test, therefore, is to lower an unprotected light where foul air is suspected; if the flame flickers and goes out, by no means enter. # Carbonic acid gas, being heavier than air, can readily be re- moved by the use of a pump, but if this is not at hand, quick lime (lime freshly burned), scattered about in large quantities, will accomplish the purpose. Treatment. — In case of asphyxiation from noxious vapors the patient should be removed as soon as possible to fresh air, and natural respiration re-established, as directed for drowning. Sun Stroke does not necessarily arise from undue exposure to the direct rays of the sun, but may proceed from a prolonged elevation of the bodily temperature, or from excessive heat en- countered when the vital forces are near the point of exhaustion. It is generally preceded for some time, usually from one to three days, by pain in the head, a feeling of weakness, disturb- ance of the sight and nausea. This attack, however, culminates, usually after the third day, in a loss of consciousness. The skin is intensely hot and dry, the temperature rising as high is 112. In fevers, if the temperature rises to 105 or 106, it is considered APPENDIX. 1 7 ] a severe case. It is, therefore, apparent that the patient is suf- fering from an excess of heat in the body. The thing to be done, then, is to lower the temperature as soon as possible. Every minute being valuable, the following treatment should be pursued: — Treatment. — Send some one for a physician. Remove as much of the clothing as possible, and place the patient in a cool and airy place, indoors or out. Cold must then be applied to the head and body, not dashed or sprinl^led, as that would only cause a needless shock; but towels wrung out of ice-water, and frequently renewed, should be placed upon the head, cracked ice placed in the arm-pits, and the body may be wrapped in cold, wet blankets. Continue this treatment until the physician arrives or the patient shows signs of consciousness, then discon- tinue, unless consciousness should again be lost or the surface of the body becomes very hot. Never in such cases administer a stimulant. Wounds. — In surgery, wounds are divided into three classes according to their cause, namely, incised^ lacerated and con- tused. There is a subdivision of this classification, of course, but this is all that is necessary for our present purpose. Incised Wounds are those made by sharp-cutting instru- ments, making what are called clean cuts; that is, there is no tearing or bruising, but the -edges are clean cut and the surface smooth. Treatment. — If the wound is simple and small, the only treatment that is required is to cleanse the edges and apply ad- hesive plaster and perhaps a bandage. But where the wound is more extensive and serious, the edges should be brought firmly together,- if possible, and held in that position by adhesive plas- ter and bandages. But when this will not answer, hold the parts together with the hands until the physician arrives. Dr. Dulles says : "In case an entire part be cut off, as an ear, or a nose, or a toe, or a finger, it should be cleansed with lukewarm water 172 APPENDIX. and put in its place, leaving to the surgeon the decision whether or not it would be worth while to try to save it. Some very remarkable cases of reunion of such parts are in record, and an attempt to save them is not to be lightly rejected." Lacerated Wounds are made by blunt tearing instruments, such as dull tools, pieces of machinery, nails, hooks, etc. These wounds are rough and ragged and usually bleed but little. They should be given surgical skill, but until this can be secured the torn parts should be cleansed by a stream of lukewarm water, then brought as near to their natural position as possible and covered with a cloth soaked in lohenol sodique, tincture of mari- gold, or laudanum, and wrapped lightly. If no good remedy is at hand, wrap in cloth wrung out of cold water. If the patient seems much depressed, administer a little brandy or wine. Contusions are what are commonly known as bruises; they are usually caused by some blunt instrument or a fall; the skin is not torn through, but is often discolored, which is dfue to the rupture of the capillaries, allowing the blood to escape into the surrounding tissues — the familiar black and blue appearance of a bruise. Treatment. — Such wounds are best treated by directing upon the wounded part a stream of water, as hot as the patient can bear it, for several minutes. This will favor the carrying off of the escaped blood. Then, after bathing the part freely with phenol sodique or laudanum, wrap in hot, wet cloths. WEIGHTS AND MEASUKES. APOTHECARIES' WEIGHT. 20 grains (gr.) make 1 scruple, sc. or 9 3 scruples make 1 drachm, dr. or 3 8 drachms make 1 ounce, oz. or § 12 ounces make 1 pound, lb. or It) SCALE OF COMPARISON. Xb oz. dr. sc. gr. 1 = 12 =: 96 = 288 = 5760 1 = 8 = 24 = 480 1 = 3 = 60 1 = 20 APPENDIX. 173 APOTHECARIES' OR WINE MEASURE. 60 minims ci]-^) make 1 fl. draclim fl. dr. or tc 8 Jl. drachms make 1 fl. ounce, fl. oz. or fg 16 fl. ounces make 1 pint. O. S pints make 1 gallon, C. SCALE OF COMPABISON. Gallon. Pints. Fl. ounces. Fl . drach ms. Minims. C. 1 0. 8 = 128 _ 1024 _ 61440 1 = 16 =r 128 — 7680- 1 = 8 1 =^ 480 60 TROY WEIGHT. 24 grains (gr.) make 1 pennyweight, dwt. 20 pennyweights make 1 ounce, oz. 12 ounces make 1 pound, lb 3% grains make 1 carat (diamond weight), k. m- 1 SCALE OF COMPARISON. OZ. dwt. 12 z= 240 1 20 1 Ik. gl". 5760 480 24 3% AVOIRDUPOIS WEIGHT. 16 drachms idr.) make 1 ounce, oz. 16 ounces make 1 pound, lb. 25 pounds make 1 quarter qr. 4 quarters make 1 hiindredweight, cwt. 20 hundredweight make 1 ton, T. 100 pounds make 1 cental, C. SCALE OF COMPARISON. T. cwt. qr. lb. oz dr. 1 = = 20 =: SO = 2000 = 32000 — 512000 1 = 4 = 100 = 4000 ■ — 25600 1 ^ 25 1 = 400 16 ] — 6400 256 16 A gallon contains eight pints. A pint contains sixteen fluid ounces. A fluid ounce contains eight fluid drachms. A fluid drachm contains sixty minims (Tn)- 174 APPENDIX. APPROXIMATE MEASUEEMENT, A wineglass contains two fluid ounces. A teacup contains four fluid ounces. A teaspoon of powder contains one-half drachm. A tablespoon of powder contains two drachms. One drop of essential oils contains one-half minim. One drop of water contains one minim. From Oould's Medical Dictionary. The following table of approximate and exact equivalents of the metric and common weights and measures may prove serviceable : Unit of Measurement. 1 inch, 1 centimeter 1 yard, 1 meter (3D. 37 1 foot, 1 kilometer (1000 meters), 1 mile, (Vioo meter), inches). Approximate Equivalent. 2 ^2 cubic centimeters, 0.4 inch, 1 meter, 1 yard, 30 centimeters, % mile, 1% kilometer. Accurate Equivalent. 2.539 0.393 0.914 1.093 30.479 0.621 1.609 SUEFACE. Unit of Measurement. 1 hectare 1 acre. (10,000 sq. meters). Approximate Equivalent. 2% acres, Yg hectare. Accurate Equivalent. . . 2.471 . . 0.404 WEIGHT, Accurate Approximate Equivalent. Equivalent. . 151/2 grains, 15.432 . 0.064 gramme, .... 0.064 . 2y. lbs. avoirdupois, . . 2.204 % kilogramme, .... 0.453 ounce, Troy or apothecary (480 28^/3 grammes, .... 28.349 grains), 31 grammes, 31.103 Unit of Measurement. gramme, grain, kilogramme (1000 grammes), pound avoirdupois, . . . . ounce avoirdupois (437% grains) BULK. Unit of Measurement. Approximate Equivalent. 1 cubic centimeter 0.06 cubic inch, . 1 cubic inch, l^y^ cubic centimeters, 1 liter (1000 cubic centimeters), . 1 IT. S. Standard quart, 1 United States quart, ... 1 liter, .... 1 fluid ounce 29% cubic centimeters, Accurate Equivalent. 0.061 16.386 0.946 1.057 29.570 INDEX. Abbreviations, 8. Abrasion of the teeth, 50. Abscesses, 34. Alveolar, 34, 63. of the antrum of Highmore, 62. Absorption of roots, 27. Acetic acid, 130. Acids, antidotes for. 166. burns from, 148. their effect upon the teeth, TA. Aconite, 78. Acute inflammation, 30. Adrenalin, 126. Alcohol, 98. Alkalies, 166. antidotes for, 106. Alum, 125. xVlveolar abscesses, 34. Alveolaris pyorrhoea, 43. Amelloblasts 10. Ammonia, 100. Amyl nitrite, 102. Anesthesia, treatment of dangerous dangers of, 85. symptoms in, 95. stages of, 80. Anesthetics, general, 79. local, 82, 93. Analgesics, 76. Anatomy of the teeth, 19. Anemia, 29. Angel's method of fixation, 59. Anodynes, 76. Anomalies of the teeth, 28. Antacids, 146. Antidotes, 166. Antipyretics, 119. Antipyrine, 119. Antiseptic mouth-washes, 45. Antiseptics, 131. Antizymotics, 131. Antrum of Highmore, diseases of, 62. Apoplexy, 148. Aristol, 137. Arsenic, 112. Articulation of the teeth, 23. Artificial palates, 67. respiration, 153. Astringents, 123. Atropine, 78. B. Bandages, 158. Belladonna, 78. Bicarbonate of soda, 146. Bichloride of mercury, 132. Bites, dog, 167. serpent and insect, 169. Bleeding, 161. Blood stasis, 34. Borax, 146. Bromide of ethyl, 91. Bromine, bromides, 75. Bruises, 172. Burns, 148. c. Calcareous deposits, 69. Calcification of the pulp, 16. of the teeth, 13, 15. Campho-phenique, 141. Camphor, 101. Capsicum, 103. Carbolic Acid, 129. Caries in relation to sex, 52. of the teeth, 49-55. Caries, relative location of, 55. therapeutics of, 56. Catalepsy, 149. Cathartics, 143. 175 176 INDEX. Caustics, 127. Cementoblasts. 13. Cementum, 13, 14. Chemical irritants, 120. Chloral, 76. Chloride of ethyl, 95. of zinc, 114. Chloroform, 86. mortality, 87, 88. physiological action, S8. therapeutic uses of, 87. Choking, 150. Chronic inflammation, 30. Cimicifuga, 109. Cinchona, 106. Cinnamon, 141. Citrate of magnesia, 143. Classification of tue teeth, 19. 20. Cleaning teeth, 72. Cleft palate, 65. Cloves, oil of, 104. Cocaine, 93. Collodion, 145. Congestion, 33. Contusions, 172. Convulsions. 150. in teething, 25. Corn ergot, 127. Corrosive sublimate, l'o2. Creasote, 139. Crowns of teeth, 21. Cuts, 171. Cystic tumors, 38. D. Dangers of anesthesia, 85. Deaths from teething, 25. Deciduous teeth, decalcification of. 25. germination of, 10, 11. Defects of the palatine organs, 65. Dental Abrasion, 56. caries, 49-55. relative location of, 55. Dental caries, therapeutics of, 56. erosion, 46. medicine, 74. pathology, 29. periostitis, 42. pulp, 16, 17. therapeutics, 29. Dentinal fibrils, 13. Dentine, 14. calcification of, 13, 14. formations, 40. organ, 10. Dentition, 23. lesions incident to, 24. second, 27. third, 28. Denture, permanent, 17. temporary, 17. Deposits upon the teeth, 69. Development of teeth, 9, 10. Devitalization of pulp, 39. Digitalis, 108. Disease. 29. Diseases of dental pulp and meip- brane, 38. of hard dental structure, 49. of maxillary bones, 57. Disinfectants, 131. Dislocation of the inferior maxil- lary, 61. treatment of, 62. Dislocations, 150. Dover's powders, 77. Drowning, treatment of. 151. Drugs, miscellaneous. 144. E. Electrozone, 142. Emergencies, 148. Enamel, 9, 14. calcification oi, 12. formation of. 9, 11. organ, 9. Enamelblasts. 10. Epilepsy, treatment of, 155. Epithelium, 9. Epsom salts, 143. Epulis tumors, 33. Ergot. 127. Erosion, dental, 46, 4 4'. Eruption of the teeth, 23, 27. Escharotics, 127. Ether, 82. action of, 82, 84. administration of, 83. mortality, 88. physiological action, 88. INDEX. 177 Ethyl bromide, 91. chloride, 95. Etiology of dental caries, 50. Bucaine hydrochlorate, '"A," Uil Eucalyptus, 109. Eugenol, 104. Exhaustion from heat, 155. Exostosis, 47, 48. Exposed pulp, 39. Extraction of teeth, 07. hemorrhage following, GO. indications justifying, 07, OV. F. Fainting, 158. Ferrum, 111. Fistula, 34. Follicles of the teeth, 11, 12. Foreign bodies in the throat, 150. Formalin, 138. Formula of permanent teeth, 20. of temporary teeth, 19. Fowler's solution, 112, Fractures, 158. of alveolar process, 57. of maxillae, 57. treatment of, 58. Freezing, 160. gum before extracting, 95. G. Gallic acid, 124. Gangrene of the pulp, 42. Gas, administration of, 89. liquefied, 90. Gas, mortality of, 91. nitrous oxide, 89. Gases, noxious, 170. Gaultheria, 139. Germination of the teeeth, 9. Glacial phosphoric acid, 118. Glycerin, 144. Green stain, 09. H. Hard dental structure, diseases of, 49. Heat-stroke, 155. 14 Hemorrhage, IGl. after extraction, 09, 103. from lungs, 1G4. from nose, 162. from stomach, 1G3. Hemostatics, 12G. Hutchison teeth, 54. Hydrochloric acid, 118. Hydrogen peroxide, 133. Hydrophobia, 1G7. treatment of, x^6. Hypercementosis. 47, 48. Hyperemia, 29. Hypertrophy, 31. of the pulp, 40. Hypnotics, 74. Incised wounds, 171. Induration, 32. Inflammation, 29. acute, 30. chronic, 30. of the pericemental membrane, 42, 43. of the pulp, 38. of the temporo-maxillary artic- ulation, 61. Injuries and diseases of maxillary- bones, 56. Interdental splints, 58, 59. Interglobular spaces, 14. Intoxication, 164. Iodine, 121. Iodoform, 130. Iron, 111. Irritants, 120. Irritation of pulp, 17. Ischemia, 29. L. Lacerated wounds, 172. Lancing of gums, 25. Laxatives, 142. Lime Water, 146. Lunar caustic, 128. M. Magnesia, 143. Materials used for splints, 160, 178 INDEX. Maxillary bones, diseases and inju- ries of, 56. Mechanical irritants, 120. Medicine, dental, 74. Membrane, pericemental, 17. Miscellaneous drugs, 144. Monsel's solution, 111. Morphine, 77. Mouth-washes, 56. Mucous deposits, 70. effects of, upon the teeth, 70. Myrrh, 103. N. Naphthol, 140. Narcotics, 74. Nausea treatment of, 164. Necrosis of the jaws, 59. Nervous irritants, 121. Nitrate of Amyl, 102. Nitrate of silver, 128. Nitric acid, 117. Nitrite of amyl, 102. Nitrous oxide as an anesthetic, 89. manner of preparation of, 89. mode of administering, 70. mortality of, 91. Nodular dentine, 41. Nut-galls, 123. Nutrition of the teeth, 18. Nux vomica, 107. 0. Obturators, 68. Occlusion of the teeth, 23. Odontalgia, 56. Odontoblasts, 13. Oil of cloves, 104. of eucalyptus, 109. Opium, 77. Organ, dentine, 10. enamel, 9. Osteodentine, 41. Oxychloride of zinc, 115. Oxyphosphate of zinc, 115. Pain after filling, 40. Palates, artificial, 67. I'alatine organs, defects of, 65. Pajiilla, dentinal, 10. Paralysis, 148. Pathology, dental, 29. Peppermint, 105. Pericementitis, 42, 43. Peridental membrane, 17. Permanent denture, 19. tooth follicles, 12. Permanganate of potassa, 135. Peroxide of hydrogen, 133. of sodium, 135. Persulphate of iron, 11. Peruvian bark, 106. Phenol sodique, 130. Phosphoric acid, 113. Physical effects of anesthesia, 84, 88. Physiology of the teeth, 14. Pitted teeth, 53. Plethora, 29. Poisons and their antidotes, 165, 166. Polypus, 40. Prepared chalk, 147. Primary dentition, 23. - Prophylaxis, 56. Proximal surfaces, 5o. Pulp, calcification of, 16. devitalization of, 39. diseases of, 38. exposure of, 39. gangrene of, 42. hypertrophy of, 40. inflammation of, 38. irritation of, 17. nodules, 41. structure of, 16, 17. Pulpitis, 43. Purgatives, 137. Pus and pus formation, 31. Pyorrhoea alveolaris, 43. Pyrozene, 134. Quinine, 116. R. Removal of temporary teeth, 25. Resolution, 31. INDEX. 179 Kespiration, artificial, 153. Resuscitation from drowning, 151. Rhubarb, 143. S. JSaliva, 70. ISalivary calculus, 69, 70. composition of, 70. Sandarach, 145. Sanguinary calculus, 72. Scalds, treatment of, 148. Sea-sickness, 169. Second dentition, 27. Secondary dentine, 40. Sedatives, 119. Senna, 143. Shedding of temporary teeth, 215. Silver nitrate, 128. Snake bites, 167. Sodium chloride, 105. Sodium peroxide, 135. Splints, 59, 160. Sprains, 169. Staphylorrhaphy, 66. Starvation, 170. Stimulants, 98. Stomalitis, 37. Strangulation, 170. Structure of the pulp, 16. of the tfeth, 14. Strychnine, 107. Styptics, 126. Suffocation from gas, 170. Sulphate of iron, 112. of magnesia, 143. Sulphuric acid, 116. aromatic, 116. Sun-stroke, treatment of, 170. Supernumerary teeth, 28. Suppuration, 31. Surface of teeth, 21, 22. T. Tannic acid. 123. Tartar of salivarj' calculus, 69. Teeth, anatomy of, 19. articulation of, 23. calcification of, 13, 15. cementum of, 14. classification of, 19, 20. crowns of, 21. decalcification of, 25. dentine of, 14. development of, 9. enamel of, 9, 13. eruption of, 23, 27. extraction of, 67. follicles of, 12. germination of, 9. occlusion of, 23. permanent, eruption of, 27. primary, eruption of, 23. pulp of, 16. relative proportion of roots and crowns of, 21. structure of, 14. supernumerary, 28. surfaces of, 21. temporary, 23. absorption of, 25. Teething, 24. convulsions in, 25. deaths from, 25. treatment during, 25. Temporary denture, 19. Therapeutics, 29. of caries, 56. Third dentition. 28. Tonics, 106. Tooth powder, 56. pulp, 16. Trichloracetic acid, 131. Tumefaction, 33. Turpentine, 122. U. Ulceration, 34. I'se of tooth-brushes, 56. 180 IMjEX. Vascular tumors, 33. Velum, artificial, 67. Vomiting, to allay, 164. to produce, 165. W. Weights and measures, 172, 173. Wounds, contused, 171. incised, 171. lacerated, 172. Z. Zinc, 114. chloride, 114. oxychloride of, 115. oxyphosphate of, 115. FOR MEDICAL STUDENTS WEBSTER'S DIAGNOSTIC M¥J^ np U 1^ -pi Q CHEMICAL. BACTERIOLOGICAL, Jl^ M, n KJ KJ \3 AND MICROSCOPICAL By Ralph W. Webster, m d.. ph.d. , Ass/. Professor of Pharmacologic Therapeutics, and Instructor in Medicine, Rush Medical College ( University of Chicago): Pathologic Chemist, Cook County Hospital. Fourth Edition, Revised, Enlarged, xxxvi -\- 738 pages, with 37 Colored Plates and 171 other Illustrations. Cloth, ^554.50 MONTGOMERY'S PRAC- TICAL GYNECOLOGY By Edward E. Montgomery, m.d., Professor of Gynecology in Jefferson Medical College ^ Philadelphia ; Gynecologist to the Jefferson and St. Joseph'' s Hospitals, etc. Fourth Edition. Rearranged. I'horoughly revised and in part rewritten. With 589 Illustrations, many of which are new. 3 in colors. Octavo. 879 pages. Cloth, ^6.00 EDGAR'S OBSTETRICS FOURTH EDITION By J. 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