G^\ A PRACTICAL TREATISE THE DISEASES OE WOMEN. STANDARD MEDICAL WORKS. By Professors LANDOIS and STIRLING. HUMAN PHYSIOLOGY (A Text-Book of) : Including Histology and Microscopical Anatomy, with special reference to Practical Medicine. By Dr L. LANDOIS, of Greifswald. Translated from the Fourth Gennan Edition, mth Annotations and Additions, By WM. STIRLING, M.D., Sc.D., Reg. Prof. Inst, of Med., University of Aberdeen. In Two Vols. , with very Numerous Illustrations^ Royal 8vo, t Handsome Cloth. GENERAL CONTENTS. Vol. I.— Physiology of the Blood, Circulation, Respiration, Digestion, Absorption. Animal Heat, Metabohc Phenomena of the Bod}'. Price i8s. Vol. II.— Secretion of Urine; Structure of the Skin; Physiology of the Motor Apparatus ; the Voice and Speech ; General Physiology of the Nerves ; Electro-Physi- ology ; the Brain ; Organs of Vision, Hearing, Smell, Taste, Touch ; Physiology ot Development. '•■ So great are the advantages offered by Prof Landois' Text-Book from the exhaus- tive and eminently practical manner in which the subject is treated, that it has passed through fom- large editions in the same number of years. Dr Stirling's annota- tions have materially added to the value of the work. . . . Admirably adapted for the practidoner. . . . with this Te.xt-Book at his command, no Student could fail in his examination." — Lancet. " One of the most practical v^^ORKS on Physiology ever written." —Britisk Medical yournal. By WM. AITKEN, M.D., F.R.S., Professor of Pathology in the Army Medical School ; Examiner in Medicine for the Military Medical Services of the Queen. THE SCIENCE AND PRACTICE OF MEDICINE. In 2 vols., Seventh Edition, 42s, " The Standard Text- Book in the Enghsh language. "—£^z«. Med. Journal. OUTLINES OF THE SCIENCE AND PRACTICE OF MEDICINE. Second Edition, 12s. 6d. By a. WYNTER BLYTH, M.R.C.S., F.C.S., Public Analyst for the County of Dei'on. HYGIENE AND PUBLIC HEALTH (A Dictionary of). "With Illustrations, 28s. " A work of extreme value." — Med. Times and Gazette. FOODS: THEIR COMPOSITION AND ANALYSIS. 1 6s. Second Edition. " Should be in the hands of every Medical Practitioner."— T/zf Lancet. POISONS: THEIR EFFECTS AND DETECTION. 1 6s. Second Edition. " A sound and practical Manual of Toxicology, which cannot be too warmly recom- ended. . . . Discusses substances which have been overlooked. "—0(;;«?Va/ A'ew.r. CHARLES GRIFFIN AND COMPANY, LONDON. EROSIONS, GRANULATIONS, AND LACERATIONS OF THE CERVIX UTERI. {After Munde, Croom, and Savage), Xo. 1. The Cervix Uteri, free from disease. „ 2. Slight Erosion of the Cervix Uteri. „ 3. Follicular Cervical Endometritis. ., 4. Granular Cervix, with Laceration and Eversion. ,, 5. Extreme Granulation of the Cervix, with Parenchyinatous thickeiiiut,'. ,, 6. Great Bi-lateral Tearing, Granulation, and Ectropion ; the sides diawn asunder liy Tenacula. Digitized by the Internet Archive in 2010 with funding from Open Knowledge Commons http://www.archive.org/details/practicaltreatisOOthor f: A "flu/ (/iHC PRACTICAL TREATISE DISEASES OF WOMEN.^ PREPARED WITH SPECIAL REFERENCE TO THE WANTS OF THE General Practitioner and Advanced Student. BY JOHN THORBURN, M.D., F.R.C.P., PROFESSOR.OF OBSTETRIC MEDICINE, THE OWENS COLLEGE AND VICTORIA UNIVERSITY, MANCHESTEK. OBSTETRIC PHYSICIAN TO THE MANCHESTER ROYAL INFIRMARY, ETC., ETC. Mitb CbromoslLitbograpb aiiD over 200 Jllustratiotis. LONDON: CHARLES GRIFFIN AND COMPANY EXETER STREET, STRAND. 1885. >^ HIS COLLEAGUES AND TO THE STUDENTS PAST AND PRESENT OF Jlb[c ©wens College Scbool ot /IDet)icine AMONG WHOM HE HAS PASSED MANY OF THE HAPPIEST DAYS OF HIS LIFE THIS WORK J S Co I^D lALLY JnSCI^BED BY Zhc autbor. ISCr 103 .IS PEEFACE. The following work, undertaken at the request of my Publishers, has l^een written with a very definite purpose. It is intended to afford the general practitioner of medicine, or the advanced student, a ^dew of the present state of gynaecological knowledge and practice. Avoiding all personal "hobbies," and, as far as possible, all controversial matters, and using such judicially selective skill as I (iould, without dogmatism, bring to bear upon the discussion of each topic, — 1 have endeavoured to go over the whole gTound in such a manner as should be most practically useful in those emergencies which are daily occurring to every general practi- tioner. 1 trust that a. few years spent in such practice, and followetl by nearly twenty of class-room and clinical teaching, have in some degree fitted me for the task. If I have, on the whole, given such sound, practical, and fairly- judicial advice as will enaljle a few of the rising generation of practitioners to escape the errors and avoid the difficulties of m}- own early career, I shall be more than conipensated for any laboui- involved in the task. My sincere thanks are due to Mr A. H. Young, IMJ.C.S., whose facile pencil lias supplied the original illustrations ; to Mr Albau Doran, for some excellent (original woodcuts from his work on ovarian tumours; to Dr AVilliam Yeats and I)r Arthur liobinsou, for much valualjle assistance in preparing tlie manuscript ; aud to ray son, Mr William Tliorburn, M.B., B.S., for assistuig me ^^J1 PEEFACE. in passing the work through the press, and in various other ways. I have also to thank Messrs Maw, Son, & Thompson, and Messrs Krohne & Sesemann of London, and Messrs Tiemann and Co. of New York, for the courtesy with which they placed their catalogues of instruments at my disposal. J. THOEBUEN. Manchester, May 1, 1885. CONTENTS. CHAPTER I. The Methods and Means commonly employed in Diagnosis. Manual Examination, including Abdominal Palpation, Digital Examination or Vaginal toucher, Bi-manual Examination, Rectal and Vesical Examina- tion, &c. Insteitmental Examination, including the use of Specula, Sounds, and Tents. Inspection of Mop.bid Discharges, CHAPTER II. Diseases of the External Genital Organs of the Female. Aphthae. Herpes. Diphtheria. Lichen. Acne. Eczema. Parasites. Warts. Boils. (Edema. Pruritus. Syphilis. Cancer. Lupus. Noma. Vulvitis. Abscess. Cysts. Varicocele. Thrombus. Hernia. Hjalrocele. Labial Tumours. Hypertrophy. Vascular Caruncles and Degenerations. Fissures. Adhesions. Abnormalities of the Hymen. Coccj'godynia. Ruptured Perineum, &c., ....... 36 CHAPTER III. M KTHODS AND MeANS COMMONLY EMPLOYED IN SuRGICAL TREATMENT. Instruments used in Local Treatment. Methods of Introducing Remedial Substances. General Management of GYNiECOLOGiCAL Operations. Preparation. Antiseptics. After- Treatment. ANiESTHESiA, . . 72 CHAPTER IV. Hygienic and Medical Treatment in their Relation to Female Diseases. Influence of Menstrual Periodicity. Food. Stimulants. Clothing. Exercise. Bathing. Education. Chlorosis, its Nature and Treatment. Neurasthenia in its various Forms, . . .96 CHAPTER V. Diseases of the Vagina. Vaginitis, Acute and Chronic. Leucorrhcca. Tumours and Growths. Foreign Bodies. Wounds, Ulceration, and Fistula;. Occlusion. Prolapse, . . . . . .114 CONTENTS. CHAPTER VI. PAUE Congenital Malformations of the Genital Teact. Ovaries and Fallopian Tubes, Uterus, Vagina, and Vulva. Hermapliroditism. Results of Ati'esia, and Proceedings for its Removal, ..... 135 CHAPTER VII. Ovulation, Menstuuation, and their Disorders. Amenorrlicea. Sup- pressed Menstruation. Scanty Menstruation. Menorrhagia. Metror- rhagia. Dysmenorrhcea. Vicarious Menstruation. The Menopause, . 154 CHAPTER VIII. Diseases of the Uterus. Infantile Uterus. Stenosis of the Cervix Uteri. Uterine Atrophy. Inflammation of the Uterus (Metritis), including Acute and Chronic, Parenchymatous and Mucous, Corporeal and Cervical, Metiitis, ......... 194 CHAPTER IX. Diseases of the Uterus — continued. Ulcerations and Abrasions, Hyper- trophy, and Lacerations of the Cervix Uteri. Chronic Hypertrophy and Subinvolution of the Body or Cervix, ..... 229 CHAPTER X. Diseases of the Uterus — continued. Fibro-myomata or Fibroid Tumours. Uterine Polypi. Fibro-cystic Tumours, ..... 256 CHAPTER XL Diseases of the Uterus — continued. Uterine Displacements. Theu' General Mode of Causation. Prolapse of the Uterus and Vagina. Pseudo-pro- lapse. Elevation of the Uterus. Forward Displacements, Anteflexion and Anteversion. Backward Displacements, Retroflexion and Reti'over- sion. Mobile Uterus. Lateral Displacements, .... 286 CHAPTER XII. Diseases of the Uterus — contimied. Mechanical Supports used in the Treatment of Displacements of the Uterus and Vagina. Belts, Pes- saries, &c., . . . . . . . . 320 CHAPTER XIII. Diseases of the Uterus — continued. Inversion, .... 344 CHAPTER XIV. Diseases of the Uterus — contimied. Malignant Diseases. Cancer of the Cervix. Cancer of the Body. Sarcoma, ..... 357 CONTENTS. XI CHAPTER XV. I'AGK Diseases of the Ovary. Prolapse. Neuralgia. Inilamniation, Acute and Clirouic. Peri-ovaritis. Abscess. A])oplexy. Ovarian Tumours, Solid and Cj-stic, ........ 380 CHAPTER XVI. Diseases of the Ovary — continued. Ovarian Tumours. Their Size, Cover- ing, Consistency, Vascular and Nervous Supply, Pedicle, Contents, Progress, Accidents, and Complications. Their Symptomatology and - Physical Signs. Their Diagnosis and DilFerentiation, . . . 404 CHAPTER XVII. Diseases of the Ovary — continued. Ovarian Tumours. Treatment, by Exploration, Tapping, Drainage, or Piemoval. Ovariotomy and Oophor- ectomy. ......... 440 CHAPTER XVIII. Diseases of the Fallopian Tubes. Congenital Abnormalities, Morbid Growths, Undue Patency. Constriction. Inflammation, Acute and Chronic. Abscess (Pyo-salpinx). Tubal Dropsy (Hydro-salpinx). Hffimato-salpinx. Extra-Uterine Pregnancy, . . . 464 CHAPTER XIX. Pelvic Disorders. Pelvic Inflammation, including Pelvic Peritonitis, Perimetritis, or Peri-uterine Peritonitis ; and Pelvic Cellulitis, .Para- metritis, or Peri-uterine Cellulitis. Pelvic Hematocele. Pelvic Abscess, . 483 CHAPTER XX. . Dysrareunia, Vaginismus, Sterility, . ' . . . 512 CHAPTER XXI. Some Affections of the Female Urethra, Ureters, Bladuei;, and Rectum, ......... 526 APPENDIX. Thr Symptoms and Signs of Pregnancy from the Point of \'ik\v of Diagnosis and Differentiation, ..... .'>56 LIST OF ILLUSTEATIONS. The sources from which these are directly or indii-ectly derived are indicated in ordinary type. The italics refer to illustrated catalogues of instruments. When there is no reference, the figures have either been drawn hy Mr A. H. Young, F.R.C.S., or engraved from the instructions of the author. FIG. 1. Chad wick's Gynacological Table {Coclman &; SJmrtleff), 2. Colin's Reflecting Lamp, 3. Electric Light applied to the Tubular Specirlum, 4. Do. do. Duck-bill Speculum, 5. Diagrammatic View of Douglas's Pouch (Ranney), 6. Bi-manual Examination (Schrceder), 7. Fergusson's Tubular Speculum {Maw), 8. Speculum Forceps {ibid.), 9. Playf air's Uterine Applicator {ibid.}, 10. Barnes's Bi-valvular Speculum (iMt?.), 11. Cusco's Bi-valvular Speculum (i&ifZ.), 12. Meadows's Si^eculum {ibid.), 13. Knott's Speculum (i6zVZ.), 14. Reid's Speculum, closed, . 15. Do. do. open, . 16. Scanzoni's Speculum {Maw), 17. Sims's Duck-bill Speculum (Tie/;ia)Mi), 18. Position for the use of the Duck-bill Speculum, 19. Sims's Vaginal Repressor {Tiemann), 20. Uterine Tenacula {ibid. ), . 21. Fine Uterine Vulsellum {ibid.), . 22. Duck-bill Specukmi and Vaginal Repressor combined {Man:), 23. Emmet's Self-retaining Speculum {Tieriumn), 24. Neugebauer's Speculum {Maw), . 25. Sir J. Y. Simpson's Uterine Sound {Tiemann), 26. Sound recommended by the author, 27. Retroverted Uterus tied down by adhesions (AVinckel), 28. Jennison's Flexible Sound {C'odman & Shurtleff), 29. Sponge, Laminaria, and Tupelo Tents {Mate), 30. Expansion of Tupelo Tent (filunde), 31. Barnes's Tent Introducer {Maic), . 32. External Organs of Generation (Sappey), 33. Follicular Vulvitis (Thomas), 34. Labial Abscess {ibid.), 35. Sims's Glass Vaginal Dilator {Maio), 36. Barnes's Vaginal Dilator {Krohnc d- Sesern PAGE 2 2 3 3 7 10 13 14 14 15 15 16 16 17 17 17 17 18 19 19 20 20 21 21 22 23 26 27 28 29 30 36 49 50 52 52 LIST OF ILLUSTKATIONS. xm FIG. 37. 38. 39. 40. 41. 42. 43. 44. 45. 46. 47. 48. 49. 50. 51. 52. 53. 54. 55. 56. 57. 58. 59. 60. 61. 62. 63. 64. 65. 66. 67. 68. 69. 70. 71. 72. 78. 74. 75. 76. 77. 78. 79. 80. 81. 82. 83. 84. 85. 86. 87. Elephautiasis of the Vulva (Mayer), Ear Scoop, suitable for urethral use {Tiemann), . Wells's jSTeedle-holder {Krohne & Sesemann), American Needle-holder {Maw), . Hagedorn's Needle-holder {Krohne d- Sesemann), Straight Perineal Needle, .... Introduction of First Suture in Perineorraphy, Quilled Suture of Perineum (Baker Brown), Sims's Sponge-holder {Krohne & Sesemann), Emmet's Knife-holder {ibid.), Bozemann's Scissors {ibid.). Laterally Curved Needle in Handle {Tiemann), . Tyler Smith's Tubular Needle {Arnold), . Perineum Freshened, with Sutures introduced, . Aspirator Needle {Maio), .... Rasmussen's Aspirator {Krohne & Sesemann), Growth transfixed by Needle to secure hold for Ecraseur Chassaignac's Chain Ecraseur [Maio), Braxton Hicks's Wire Ecraseur {Krohne & Sesemann), Galvanic Ecraseur {ibid,. ), ... Paquelin's Cautery (Coxeter), Sims's Curette {Krohne & Sesemann), Palfrey's Scarificator {Maw), Silver Wire Twisting (Emmet), . Higginson's Syringe {Maiv), Yaginal Douche {Krohne & Sesemann), Double Nozzle for Vaginal Syringe {Maiv), Instrument for Plugging the Cervix Uteri (Chrobak), Barness's Tampon Introducer {Maiv), Sims's Tampon Extractor {Tiemann), Sims's Sigmoid Catheter {Maio), . The Skene-Goodman Self-retaining Catheter {Tiemann), The Pelvic Viscera in Profile (Houston), . Vertical Section of the Vagina (Hart and Barbour), Section of the Pelvic Viscera (Ranney-Foster), Paring Fistula by Scissors (Churchill et Leblond), Emmet's Curved Scissors {Tiemann), Emmet's Double Carved Scissors {ibid.), . Fi.stula, with Wires inserted (Churchill et Leblond), Rudimentary trace of Uterus (Schrceder), Rudimentary Uterus {ibid.), Uterus Unicornis (i5ic?.), . Uterus Duplex (Thomas), . Uterus Septus (Schrceder), Uterus Bicornis {ibid. ), Congenital Atresia Vaginae, Five Diagrammatic Figures, illustrating the development of the Genito-urinary Organs and Rectum (Schrceder), ) Marie Madeleine Lefort, a remarkable example of Pscudo-hermapliroditism (Churchill et Leblond), ...... PAGE 55 56 62 62 63 63 64 65 67 67 68 68 6b 69 73 74 74 75 75 76 77 77 78 79 80 81 82 84 85 85 93 93 114 115 115 130 131 131 132 138 138 139 139 140 140 142 143 143 143 143 143 144 XIV LIST OF ILLUSTEATIOXS. FIG. 89. 90. 91. 92. 93. 94. 95. 96. 97. 98. 99. 100. 101. 102. 103. 104. 105. 106. 107. 108. 109. 110. 111. 112. 113. 114. 115. 116. 117. 118. 119. 120. 121. 122. 123. 124. 125. 126. 127. 128. 129. 130. 131. 132. 133. 134. 135. 136. 137. 138. 139. Section of Pelvis of the same (Churchill et Leblond), Hfematometra (Schrceder), Hfematokolpos {ibid.), Adult and Adolescent Human Ovaries. Dysmenorrhceal Membrane (Coste), Priestley's Uterine Dilator {2Iaw), Sims's Uterine Dilator [Tiemann), Tait's Uterine Dilator (Tait), Simpson's Hysterotome {Tiemann), Kuchenmeister's Uterine Scissors (ibid.). Glass Intra-uterine Stem Pessarj' {Erolme cfc Sesemann), Uterus Infantilis (Schrceder), Formal and Infantile Uterus, Simpson's Galvanic Stem Pessary {Krohne dc Sesemann), Barnes's Galvanic Stem Pessary {ibid. ), Long Conical Cervix Uteri (Churchill et Leblond), Virgin and Parous Uterus contrasted (Sappey), . Uterine Ointment Syringe {Tiemann), Atthill's Intra-uterine Cannula {Moao), . "Watch-spring Piing Pessary {Krohne & Sesemann), Watch-spring Pessary with perforated Diaphragm, Fissiu'ed and Granular Cervix Uteri (Schrceder), . Ulceration of Prolapsus Uteri (Thomas), . Pallen's Operation for Elongated Cervix, . Stellar Laceration of the Cei-vix Uteri (Emmet), . Unilateral Tear of the Cer\-ix Uteri {ibid.), iDiagi'ammatic Illustration of the steps of Emmet's Operation for Lacerated Cervix Uteri, ..... Lacerated Cervix after Denudation (Emmet), ... Pseudo-prolapsus Uteri. Hypertrophy of the Supra-vaginal portion o the Cervix (Schrceder), ..... Multiple Fibroids of the Uterus (Boivin et Duges), Cavernous Uterine Fibroid (Schrceder), .... Typical foiTas of Fibro-myomata, ..... Cervical Fibro-myoma (Schrceder), .... Fibroid Polypus of the Uterus (ChurchiU et Leblond), . Aveling's Pol33)trite {Tiema/iin), ..... Ordinary Stages of Prolapsus Uteri, .... Prolapsus Uteri with Persistent Eeti'ofiexion (Schrceder), Sims's Operation for Elytrorraphy (Thomas), Emmet's Oj)eration for Elytrorraphy (I'&ic?.), Pseudo -prolapsus Uteri. Hypertiophy of the Intra-vagmal portion of the Cervix (Schrceder), ..... Eemoval of Cancerous Cer\"ix {Hid.), .... Schema of Forward Displacements of the Uterus, Schema of Backward Displacements of the Uterus, Bladder overlapping a Eetroflexed Utenis (Schatz), Incisions in the Cervix rec[uired in Anteflexion (Sims), . Eeplacement of Eetroflexed Uterus by Sound, Perineal Pad, vnth Belt and Straps {Krohne & Sesemann). Ball Pessary of hard material (z'izV?.), .... PAGE 145 148 148 155 180 186 187 187 188 189 190 194 195 197 197 198 198 218 220 225 225 230 231 234 240 241 S247 247 247 247 248 253 257 258 259 277 280 283 292 293 295 296 298 300 302 302 303 307 316 322 323 LIST OF ILLUSTRATIONS. FIG. 140. Gariel's Air Pessary {Kruhne & Sesemann), 141. The Roser-Scanzoui H3'sterophor (Sclirceder), 142. Barnes's Guttajiercha Stem with Bands {Krohne equal, the depth of the student's or praetitiouei's pocket should be con- sidered. The instrument should be capable of being bent into any desired shape with the aid of a little force, and should be easily made to assume its original shape, without persistent angularity. The sound should be neither too thick nor too thin— say No. 6 of English catheter scale. The point shoidd be an olive-shaped bulb, so as to indicate the passage of any obstiiiction ; but this should depend, not on a thickening of the point, but on a thinning of the instrument just below^ it. There should be no deep notches, and certainly no pro- jections, but a slight clearly-cut nick on the convexity, 2| inches from the point, should indicate the normal length of the uterus, and three or four others may be added at intervals of an inch. The nail of the directing finger can easily take cognisance of these, while they do not materially influence the breaking or bending points. For cases of great narrowing of the cervix uteri, a common silver bullet probe is used, the cervix being brought within reach by booklets or tcnacula, with the aid of the duck-bill specvdum. Fig. 26 shows a sound of the most useful pattern, the handle, in Fig. 26. — Form of Uterine Sound recommended by tlie author. accordance with the recognised custom, being rough on the concave and smooth on the convex side of the instnunent. For the ordinary use of the sound, the speculum, in any form, is not only unnecessary, but is a distinct hindrance, and this disposes of one of the objections to the tubular instrument. By a digital or bi-manual examination, the position and the mobility of the iiterus should be care- fully made out, and the instrument should be curved a little more if ther€ is a belief in, or the certainty of, the existence of uterine flexion. It must be remembered, however, that such extra ciu-ving of the instru- ment adds to the primary difficulty of introduction into the cervix. With the patient in the same position as for digital examination, or for the use of the tubular speculum, the left forefinger finds and steadies the cervix uteri, or two fingers are used if there is plenty of room. The right thumb and forefinger hold the sound lightly by the liandle, and pass it up to the os, guided by the palmar surface of the left fore- finger. The direction of the extremity of the cervix, backwards as usual, or forwards in certain cases of version or flexion, indicates the direction in which the point of the sound should at first be passed, and the handle will always assure us how the point lies afterwards, if the gxiiding finger fail to do so. Once introduced for even half an incli into the cervix, the sound 24 MODE OF USING THE SOUXD. assists in steadying it. The instrument is now gently urged onwards in the direction of the cervix until it meets with some obstacle. In ordi- nary cases this will be at the os internum, and it requires only a gentle retraction of the handle towards the perineum, and a little tiring of the obsti-uction, to overcome the difficulty. The point must now be gently turned backwards, however it may have been introduced at first, if it is believed that the uterus is so turned ; and in cases of sup- posed flexion, either backwards or otherwise, the finger of the left hand must be used to tilt up the body of the uterus, thus diminishing the necessity for unduly bending the sound. In no case must any more force be used than in passing the male metallic catheter, and it is far better to fail, and try again and again, than to use any greater force. The fewer tours de mattre the operator uses the less danger will there be of producing mischief In some instances the digital examination may have suggested a uterine displacement w^hich does not really exist, the position of the supposed uterine body being occupied by a tumour or otherwise ; and, as one object of the sound is to correct error of this kind, a gentle attempt at passage must next be made in other directions than that which is supposed to be the right one. No •WTitten directions can confer the requisite tacttis eruditus, and the student or tyro is advised not to abstain from the use of the sound in suitable cases, but to be content with safe and cautious attempts, and, in case of failure, to remember that bi-manual examination can, in many cases, supply nearly all the requisite diagnostic infonuation. No laboured argument is required to dispose of this as an objection to the use of the sound in general. When the sound has passed the os internum, or the bend of a flexed uterus, or any small obstacle, it glides along to the fundus, unless the cavity is obstructed or twisted by morbid conditions. If these are believed to exist, owing to the presence of heemoiThage or increased uterine size, a good deal of " coaxing " in different directions is allowable, but no force. In such cases a thin, flexible, male bougie may be tried ; but for this, as for the use of the probe, in great contraction of the cervix, it is better to exj)ose the parts by the duck-bill specu- lum, and to use the instmment as one would probe any sinus in other situations. The use of the sound is not wdthout danger, even in skilful and cau- tious hands. The most frequent source of danger lies in the induction of abortion, and abortions thus induced are infinitely more likely than those which are spontaneous to be followed by septicaemia or other foiTUS of metria. I fear that I am not alone among those practising gynaecology as the possessor of some sad confessions hereanent. This danger can only be obviated by observing the golden laile — Never pass the sound till you can eliminate pregnancy as a possible condition. FACTS ASCEETAIXABLE BY THE SOUND. 25 The very strictest inquiries are necessary, and in every case where there can be a doubt, in the married or unmarried, pregnancy should have the benefit of it. There is no doubtful case in which a little time will not clear up the difficulty, and either pei-mit the use of the sound or do away with the necessity for it. Perforation of the uterus is another possible accident, and one which has happened in able hands, when the uterus was softened by disease. Most gynaecologists have heard of or seen cases where the sound has passed a great deal further than it should have done, and the charit- able explanation of a dilated Fallopian tube receiving the instru- ment will rarely hold good. Fortunately, if the sound is clean and a-septic, the result is seldom formidable, though none the less to be deprecated. Inflammation of the uterus or of its surroundings is occasionally pro- duced by the sound, even when the manipulation is perfect. Whether it is that sometimes the uterus is so sensitive that no precaution will avail, or whether the sound, like the catheter, conveys septic flixids or living septic germs, it must be borne in mind that this is a real danger, imposing the necessity of absolute antiseptic cleanliness, and of being- sure that the information to be acquired by the use of the sound is worth the risk, however infrequently that may be encountered. What, then, are the diagnostic facts ascertainable by the sound? These may be conveniently given under seven heads. 1st. The patency or otherwise of the cervical canal, especially at its extremities. The patency is diminished by (a) Congenital contraction or complete atresia, or the permanently infantile state of the organ, or the long conical cervix. (b) Contraction from inflammation or other accidents. (r) Small polypi or fibroid growths in the cervix. (d) Flexion of the uterus at or close to the cervix. (e) Spasm of the internal os, which is, however, a condition denied by some authorities. The cervix is unduly patent in many cases of chronic inflammation or sub-involution, when it has been torn during labour, and, to some extent, during a menstrual period. It may be widely dilated by intra-uterine tumours, or less so by lipemorrhages. 2nd. The size, or at any rate the length, of the whole uterine cavity. The normal length is 2^ inches, and the first nick upon the sound should therefore lie close to the os externum when the point is at the fiuidus. The average post-parous uterus is a trifle longer than the average nulli- parous one. The chief causes of increased length arc (a) Pregnancy, in which condition, the soiuul, of course, shovdd nut be used. 26 FACTS ASCERTAINABLE BY THE SOUND. [h) Fibroid uterine tumours, which may twist as well as elongate the canal. (c) Sub-involution after delivery or abortion. ((/) Chi'onic inflammation. {e) Intra-uterine polypi, malignant or other growths (/) Retained products of conception. The lenglh of the cavity is sub-normal in (a) Infantile development. {h) Senile atrophy. {c) Super-involution, not common to a high degree. (c/) Inversion of the uteiiis. 3rd. The direction in which the uterus is lying — forwards, backwards, or to one side. {See Uterine Displacement, Chap. XL) Fig. 27. — Eetro verted Uterus tied dov.Ti by adhesions (after a Pliotograpli by Winckel). 4th. The mobility of the uterus. This is diminished by (a) Exudations of coagulated lymph or blood in its neighbourhood, or old adhesions resulting therefrom (fig. 27). {h) Cancerous deposits in or around the uterine body or cervix. (c) Large tumours of the ntems or neighbouring parts. (d) The sacral promontory or the iitero-sacral ligaments, in some cases of backwards displacement. The uterine mobility is increased by many of the causes which lead to its displacement {q.v.). 5th. The relation of the utenis to neighbouring parts or abnormal gi-Qwths, and its adhesion to them or the contrary. FLEXIBLE SOUNDS. 27 Gth. Tlie form and localisation of growths or substances witliin tlie uterus, more or less approximately. 7th. Tenderness of the internal uterine wall when touched by the sound. Sometimes, though rarely, the only clear evidence of endometritis is obtained in this way, though, when (jncc ascertained, it is prohibitive oi' the further use of the instrument. Of the above conditions, it will be noted that the calibi-e of the cervical canal can only be ascert;ained by the sound ; the length of the cavity may be surmised from bi-manual measurement, but cannot be certainly arrived at, owing to the varying thickness of the fundal wall. The form of intra- uterine growths, and the tenderness of the intra-uterine lining, are be- yond the range of bi-manual examination. The other conditions can be ascertained bi-manually, in some cases more, in others less easily than by the sound. The uses of the instrument as a means of treatment will be referred to when speaking of the methods of replacing the dis- placed litems. I cannot conclude this notice of the sound without mentioning a very ingenious American instrument, patented by Messrs Codman & Shurtleif of Boston as Jennison's (fig. 28). By a skilful use of fine parallel steel Fig. 28. — Jeunison's Flexible Uterine Sound. rods, united at their extremities, and enclosed in an india-rul)bcr sheath, every bend of the instrument which occurs at the intra-uterine end is reproduced in an opposite direction at the other, and thus made visible t( • the eye ; an intentional bending of the outer end produces, on tlie othei- hand, an opposite bending of the intra-uterine extremity and uterus. In its present form it is too mobile, but it contains the rudiments of a usel'ul invention for both diagnostic and therapeutic purposes. Other flexible sounds have been proposed to meet the difticultics when the uterine cavity is twisted as well as elongated ; but in such cases, where it is neces- sary to be precise, the elastic gum bougie, or silver probe, with tlio aid of the duck-l)ill speculum, meets all wants. :28 UTERINE TEXTS. Tents. Another means of diagnosis, invaluable in some instances, though less seldom required than the speculum or sound, is the tent. This is used for the piu-pose of dilating the cer\ix uteri, and so permitting the passage of the finger into the uterus to explore its cavity, or for the introduction of instninients or medicaments which are otherwise unavailable. For this means we are, as in so many other instances, indebted to Simpson, although he admits, or rather \/ exults, in having derived the necessary inspiration from a very remarkable source — Mr John Hall of Stratford-on- Avon, the son-in-law of Shake- speare, who WTOte a medical treatise in Latin, wherein he perfectly forecasts the modem sponge-tent. At his death, his wife, Susannah Shake- speare, sold the Latin manu- script to Mr Cook of the neigh- bouring town of Warwick, who published an English trans- lation in 1637. From this Simpson got the idea — not the only instance in which he tiuiied to jDractical account his favoiu-ite hobb}' of antiquarian research. A tent is a small pencil, capable of being introduced into the cervix uteri. It is composed of materials which, absorbing moistui'e from the fluids about it, expands, and so dilates the canal of the cervix. Compressed sponge was the substance originally used by Hall and Simpson, and this has, as yet, been only partially super- seded by the Lamimiria digitata, or sea-tangle, of Dr Sloan of of Ayi', or by the tupelo wood of Dr SussdorflF of New York. The sponge tent is now made by machinery, and well satiu*ated with carbolic acid or other antiseptic, but it should be less tapering in form than is commonly the case. Fig. 29 shows the usual sponge, laminaria, and Fig. 29. — Uterine Teuts. A, Spouge. B, Laminaria. C, Tupelo. SPONGE, LAMINAItIA, AND TUrELO. 29 tupelo tents. Each kind varies somewhat in the amount of its expan- sile power, but, according to my experience, there is also a great variety in this respect among different specimens made of the same substance. Fig. 30 shows the full expansion of tupelo tents of good construction. All tents should be perforated longitudinally, except at their apex, and in the case of the vegetable tents this adds to their power and rapidity of expansion, and it permits of the easy in- sertion of a probe or wire to guide them into place. They must also be furnished with a strong thread well attached to them, for the purpose of removal. Many instruments have been devised for the introduction of tents. Forceps of every kind are iisually a mistake; the more stead}- their hold, the more liable are they to adhere to the tent, and wholly or partially to with- draw it again. Barnes's instnmient (fig. 31) I find the most useful ; but it is better to have the tubular part of metal than of softer material. The tent is impaled on the wire which projects beyond the tubular sheath, and the whole is then used as if it were a uterine sound. The tent is passed, if pos- sible, nearly i;p to its full lenglh, just pro- jecting beyond the os externum. Some- times, however, one has to be content Avith a less complete inseii:ion, to be followed up afterwards by a second instnmient. While the wire is withdrawn the sheath is pressed against the tent, and so prevents its being retracted in the slightest degree. All forms of tent may be introduced in the same way, but when very small ones of laminaria or tupelo are required, they may necessitate the use of the duck-bill specidimi to allow of the tent being carefully probed in, as it were. In all cases it is well to use the largest size that can be insinuated without force, in order to avoid if possible the necessity for a second dilatation. The free use of antiseptics is necessary in every case. AH profuse secretions should be washed away, to begin with, by injections of carbolised warm water. In place of one large tent, several small ones of tupelo or laminaria may be inserted with advantage side by side ; the action ol)taincd seems to be more equable, but, of course, the Fig. 30. — Expansion of Tupelo Tent (after Munde). Tlie larger figure shows the amount of expansion ol wliicli the smaller is cap- able. The efiect of the con- striction V)y the internal os is also sho\m. so DANGERS OF L'TEEIXE TENTS. introduction is a little more tedions and troublesome. Several hours are usually required to obtain the fuU effect, and it is most convenient, and generally quite sufficient, to aUow twelve hoxu-s— from night tiU morning, or morning till night. During this time the patient must be in bed, and as quiet as possible; this is a sine qua lion. After introduction, a vaginal plug of cotton or tenax, thoroughly soaked in carbolic solution, will tend to prevent slip- ping, and afford the necessary moisture for expansion, if that is deficient. Imme- diately on removal of the tent a free vaginal antiseptic washing is imperative, before any attempt at frirther examination. As there is sometimes considerable pain dru-- iug the process of dilatation, it is well to insert a morphia suppository into the rectum, or to give a subcutaneous injection of moi-phia soon after the tent is introduced. Tf the first tent does not expand sufficiently for the object in view, it must be followed up by a second or a third. Dr Goodell {op. cit., p. 154) calls special attention, however, to what I have long felt to be the fact — that it is not usually, with due precaution, a first tent, but a second, or still more a third, which produces mischief. The reason is obvious enough ; there is much greater danger of sejrtic poisoning in dilating a cervix already somewhat cracked and fissui'ed. The dangers of the tent are real enough to cause every conscientious physician to weigh well the necessity before having re- coui-se to them. Metritis, or inflammation of the siuTounding tissues, occvu'S every now and again, and is, I suppose, almost invariably of septic character. But severe shock, and even tetamis, have been met with as a result of the mere dilatation. The ■old-fashioned hand-made sponge-tents became so hombly foetid in a very short time that it was wonderful how seldom they Avere followed by serious results; the machine-made ones, saturated with antiseptics, ai-c less objectionable. I have never met with any serious inflam- FiG. 31.— Barnes's Teut Introducer. DIFFERENT FORMS OF TENTS, THEIH RELATIVE VALUE. .'ll matory trouble from the vise of teuts in private, though 1 have seen several ver}- severe cases of ix4vic cellulitis in hospital practice, and the danger niaj^, I believe, be minimised to a very great extent if one can depend on the following conditions being strictly adhered to : — The antiseptic washings already mentioned must he matter of invariable routine — the tent itself must be thoroughly smeared with carbolic glycerine or vaseline — or, as Albert Smith recommends in the case of sj)onge-tents, they may be first well soaped and then sprinkled with salycilic acid. If possible, one dilatation must be made to suffice, and, in the event of more being necessary, it is well to avoid sponge for the later ones. One further precaution consists in being esjjecially chary of using tents at all when the patient has pre- viously suffered from uterine or pelvic inflammations. Every consulting phj'sician must often have met with cases where he has been called, perhaps twenty or thirty miles into the country, to pro- nounce upon the nature of uterine disease, which cannot be discovered with certainty until the cervix is dilated and the finger introduced into the uterus. He cannot wait for the process of dilatation, in this manner at any rate, nor return next day without much extra trouble and expense ; it is very desirable, therefore, that the practitioner in charge of the case shoiild know under what circumstances dilatation is required, and arrange to have it previously accomplished. I have so often seen much disappointment from this source that I think it necessary to call special attention to it. Authorities are by no means agreed as to the relative value of the three forms of tent in varying circumstances. My exj^erience of the tupelo tent is not yet of very long duration, but I am inclined to think that it ma}^ in time be substituted for l)oth the other varieties, unless a still superior material is found ; there must be very many suital^le vegetable products yet imtried. The metallic tube, however, with which they are freqviently perforated, is apt to protnide, and might be a source of danger in introduction, but in other respects the}' seem to me to possess the best qualities of both sponge and laminaria. Like the latter they should always be momentarily soaked in hot water before introduction ; this renders them more pliant and easy to introduce, seems to cause them to be less painful, and ensures their speedily commencing to dilate, thereby preventing their slipping. The spongc-tcnt, however carefully made, lias tlie Tuidoubtcd disad- vantage of being more liable to j^roduce foctor, and although foetor or sapros, and sepsis, are not intei'changeable terms, the alliance between them is perilously close. In expanding, the sponge becomes closely associated with the surrounding tissues, interpenetrating them to a certain extent, and thus giving rise to minute hoimorrhages wlicn forcibly removed ; the bearing of this on septicemic risks is obvious 32 INDICATIONS OF THE USE OF TENTS. enough, but there may be some counterbalancing advantages when the tents are used as a curative means. One other disadvantage of the sponge-tent is its Habihty to tear when being withdrawn ; either a small portion only may remain, or the thread may be detached, leaving nearly the whole. Removal by forceps is easy enough in theory, but not always so easy in practice, even with the aid of further dilatation. I use the sponge tent therefore only when the os uteri is already pretty large, or when I am desirous of aiming at absorption of cervical growths, as well as at dilatation. Great antiseptic precautions are, of course, necessary, and I hope ere long to be able to substitute the tupelo or other vegetable form even in such cases. The curative uses of the tent depend on the fact that its pressure within the cervical canal will not infrequently cause the absorption of granulations or small mucous polypi, or even fibroid growths, or chronic thickening of the cervix; so that it is no vmcommon event to pass a tent for the purpose of diagnosing the source of uterine haemorrhage, to find little or nothing, and yet to cure the patient of symptoms which may have lasted a very long time. Other mechanical means than tents for dilating the cervix, will be referred to later on, when treating of dysmenorrhoea or other affections which require dilatation for curative purposes. The diagnostic objects attained by tent dilatation are more important than numerous. There are, however, several aff'ections, especially those accompanied by uterine heemorrhagic discharges, with more or less en- largement of the body of the uterus, which we may suspect, or even diagnose with some amount of confidence, but about which we cannot be absolutely sure, or which we cannot certainly differentiate from one another, unless the cervix uteri will permit its to pass at least a finger into the cavity of the uterus. Among these are — 1. Polypus of the uterus or within the cervical canal. 2. Fibroid growths of the same. 3. Chronic inflammatory granulations of the endometrium. 4. Cancer or sarcoma of the uterine body. 5. Retained products of conception, moles, ttc. 6. Retained non-conceptional clots or decidua. The effect of the pressure of a tent in producing absorption, may also furnish a clue to the differentiation of early cancer of the cervix from chronic inflammatory thickening. My attention was first called to this diagnostic means by Munde {Minor Surgical GyncBcology, p. 68), and I have since been able, on more than one occasion, to satisfy myself of the non-existence of malignant disease, from the fact that very con- siderable absorption took place after the introduction of a tupelo tent, an effect which has I'emained permanently. INSPECTION OF MORBID DISCHARGES. 3S Inspection of Morbid Discharges. This must be included among the general means of diagnosis, although but a cursory mention of tlxe various forms of discharge met with is required here. The information gathered from this source is, for the most part, merely of a pi^imd facie kind, suggesting in most cases the necessity for further investigation, although occasionally we may be called, in the case of young patients or those who are unwilling to undergo further investigation, to act upon the imperfect data thus afforded. Whenever curative means are adopted merely on the ground of the discharges observed, the practitioner must never forget that he is acting entirely in the dark, and that he may be ignoring serious or fatal diseases, during the only period at which any steps could be taken for their removal. The existence of discharges may be recog- nised either by the patient's own description, by inspection of the genitals, or by the use of the speculum. In perfect health there is just sufficient mucous discharge to lubricate the passages, preventing dry- ness or discomfort, but hardly, if at all, appearing externally. This discharge, apart from the menstrual period, may be increased, diminished, or altered in various ways. We may have — 1st. A white, flocculent, or curdy discharge, sometimes seen with the speculum in considerable quantities. This is purely vaginal, and shows increased desquamation, and over-activity of the vaginal glands. 2nd. Furulent or muco-purulent discharge. This may come from the Tulva, vagina, or uterus, or from abscess opening into any of these. If very profuse extei-nally, it is probably from the vagina, or, especially if quite purulent, from abscess. In the latter case we shall have a history of pelvic or other inflammations ; in the former we yxxix.j have one of gonorrhoea or acute vaginitis, or the symptoms may be chronic and of gradual invasion. Acute vulvitis tells its own tale. Vaginal discharge is acid in reaction, and freely mixed with, or almost composed of, the tesselated epithelium of the part, while utei'ine discharge is alkaline, and contains columnar epithelium ; bvit although this is repeated from text-book to text-book, the physician does not rely on his microscope or his test papers for information which he can acquire by the eye, aided when necessary by the speculum. The marked acidity of the vaginal secretion is, however, of importance, • as its influence on the spermatozoa is sometimes a cause of sterility. 3rd. Clear glutinous discharge, like unVjoilcd white of egg. This is seldom met with exteraally, except on the rupture of a cyst, but with the speculum it may frequently be seen oozing from the cervix uteri, and is c 34 SOLID SUBSTANCES OCCASIONALLY DISCHARGED. a sign of one stage of chronic inflammation of the uterine mucous membrane, generally of its cervical part. Each of the foregoing three discharges is generally described as leucorrhcea or " whites," unless pus be present in very large quantities. 4th. Watery discharges are most frequently met with in cancerous dis- ease, and should always excite suspicion of this, whether foetid or not ; but they are also met with during pregnancy, especially in molar preg- nancy, or in the presence of benign tumours, or of that rare affection known as hydrometra. 5th. Foetid discharges may be caused by the want of ordinary cleanli- ness, or by neglected pessaries ; but, especially if of a watery and sanguin- eous character, they should always lead to an examination to ascertain the presence or absence of cancer. I have never been qviite able to satisfy myself as to the specific smell of cancerous discharge, and I have known a case where a retained sponge tent satisfied more than one acute physi- cian that cancer was present. Generally the odour of cancer is dis- tinctive enough, but the retained products of conception, polypi, or in fact anything which keeps back intra-uterine discharges, may give rise to foetor which I at least cannot distinguish from it. 6th. Sanguineous discharge, other than menstrual, will afterwards be treated of as metrorrhagia. Its occurrence from slight causes, or after the menstrual age is past, should never be overlooked. It is an occa- sional symptom of so many diseases that it is hardly possible to attempt their enumeration now. It may occur in the most common forms of chronic uterine inflammation, in slight vascular growths of the vulva, and in other minor affections, and yet it is the most common, and often the earliest indication of the gravest and most fatal disease. The only possible deduction from this is, never to neglect a careful local examination when this symptom is present. The solid discharges which are occasionally met with are, for the most part, either blood-clots or the products of conception, great care being required, as every obstetrician knows, to distinguish between the two. Abnormal conception may furnish either the fleshy mole or the vesicles of the hydatiginous mole. In addition to these we may have the unimpregnated decidvia, afterwards to be referred to when speaking of dysmenorrhoea, or much more rarely, complete blood casts of the uterus, which are independent of pregnancy, or polypi which have become separated and are expelled by the unaided contractions of the uterus, or fibroid tumours which have undergone eniicleation and expul- sion, subseqvient to more or less degeneration of their structure, or casts of the vaginal wall, whose microscopic character is suflicient, if such evidence is required, to attest their nature. Other means or methods not now referred to may occasionally serve OTHER DIAGNOSTIC INSTRUMENTS. 30 diagnostic purposes. The endoscope, for instance, is worthy of mention, but the information derived from its present developments is meagre in tlie extreme. The curette serves the purpose of obtaining substonces scraped from the uterus for microscopic investigation ; but it will be more appropriately described as an instrument for treatment (Chap. Ill), The same remark applies to the aspirator and ej.ploring needle. 36 DISEASES OF THE EXTERXAL ORGAX^S. CHAPTER II. Diseases of the External Genital Organs of the Female. Aphthae. Herpes. Diphtheria. Lichen. Acne. Eczema. Parasites. Warts. Boils. CEdema. Pruritus. Syphilis. Cancer. Lupus. ISToma. Vulvitis. Abscess. Cysts. Yari- cocele. Thrombus. Hernia. Hydrocele. Labial tumours. Hypertrophy. Vascular caruncles and degenerations. Fissures. Adhesions. Abnormalities of the Hymen. Coccygodynia. Ruptured perineum, &c. The diseases of the external organs of generation are deserving of more attention than they sometimes receive from students of gynsecology. I do not so ranch refer to those which, like cancer, compel attention by their dangerous or fatal character, or to those which, like iniptured perineum, have a special interest for the oper- ating surgeon, but to many common ailments which by their chronicity tend to produce much constant and unbearable suffering, and thus embitter the lives of not a few women. This chronicity is not always due to the natiu'e of the affections themselves, but depends also on the fact that many women have a greater reluctance to seek for early advice in such cases, where they know that a visual examin- ation will be required, than they have in the diseases of the internal organs, where there is more of the unkno\vn and therefore of that which is dreaded, and when they hope that a mere digital examination will suffice. This mental condition certainly exists, especially in private practice, and I have known ladies driven almost to the verge of insanity by simple and curable eruptions bcl'ure they would apply for advice. Little need be Fig. 32. — External Organs of Genera- tion of the Virgin Feriude. 1, labia majora ; 2, fourehette ; 3, labia minora ; 4, clitoris ; 5, urethral open- ing; 6, vestibule; 7, vagina; 8, hymen; 9, openings of ducts of glands of Bartolums ; 10, mons veneris. APHTI02, HERPES, AND DIPHTHERIA. 37 said as to the methods of examination necessary in these cases. The ordinary position on the side is most unsatisfactory for a minute inspec- tion of the external organs. If the seat of suffering is very definitely localised by the patient, we may examine in this way in the first instance, but in all cases where there is the slightest difficulty or doubt about the natiu-e of the disease, the patient must be examined in the dorsal position and opposite to a good light. The vixlva can thvis be easily exposed to view by the fingers of the left hand, while the right is at liberty to search for painful points or to use remedies. I have known much tedious suffering result from the neglect of this precaution. A common silver probe and a good magnifying glass are frequently of use to minutely localise pain or to inspect small hyper- asthetic points. Superficial Affections of the Skin or Mucous Membrane. Almost every skin affection may affect the vulva or its surroundings, but it will suffice to mention those of common occurrence, or which have any special characters when here met with. Aphthse are not infrequent on the mucous surfaces of the vulva. They have the same histological characters as those of the mouth, and to the eye present the appearance of one or more, generally many, white raised sjjots, with more or less angry redness surrounding them. They cause much itching and smarting, especiall}- the latter. I have never been able to identify or associate them with any particular condition of system or ill health, having met with them in those who were jDerfectly robust, and who had no irritating viterine or vaginal discharges. They readily yield to treatment by a saturated chlorate of potash lotion, or a weak solution of carbolic acid (1 in 40), or one of hyposul]ihite of sodium (oi. ad gi.). Herpes, similar in character to herpes preputialis, 1 liave seen occasionally in the neighbourhood of the clitoris, and the same care is required, as in the male, not rashly to mistake this for chancre. If the part is kept well smeared with vaseline to prevent friction, or the contact of irritating discharges, the herpes soon disappears. Herpes Zoster of the groin and flank sometimes extends to the labium externum (Tait). Diphtheritic exudation on the vulva and vagina is merely mentioned here as occasionally occurring in coxuiection with the systemic disease of which it is the exanthem. In the post-partum state I have occasionally seen an exudation closely resembling diplitlievia, but not necessarily 38 LICHEN, ACXE, AND ECZEMA. accompanied by fever or prostration. Schi'oeder {Ziemssen's Cydoiyadia,. vol. X. p. 494) speaks of this, and of a diphtheritic affection accompanying wounds of the vagina. I have had no opportunity of microscopically studying it ; but I think it is more allied to aphthse, and it certainly yields to the same treatment. Lichen often occurs on and around the pubes, and is best healed by dusting with a fine powder of starch and boracic acid, kept free from all admixtiu-e with moisture. If acute, as it frequently is, it will require the same constitutional treatment as when occun-ing elsewhere. Acne is very common on the pubes, and extends downwards on the external surface of the labia, even encroaching on the mucous edges. It is often very painful in this position, and simulates or runs into the inflammatory condition of ti-ue frnnincle or boil. I have not found the application of sulphur in powder, or as a glycerole, so useful here as it undoubtedly is in acne of the face or bust. The sufferers are generally out of health and require tonic regimen. I have found eucal}iDtus oil and vaseline (pi. ad si.) of service externally, but probably any antiseptic that was not too irritating would have the same effect in preventing suppuration, and leading to absorption. Eczema is by far the most common of the skin affections which attack the external organs ; and whether it affects the mucous surface of the labia or their outer surface^ or spreads to the abdomen, perineum, nates, or thighs, it is usually a source of intolerable discomfort. The itching it produces is sometimes suflicieut to drive the patient from society ; and when by scratching, which is utterly imcontroUable, and by the drying Tip of the discharges, crusts and cracks are formed, and these again are rendered sodden by fresh discharge from the eczema itself, or from the mucous tracts above, the condition of the patient becomes most pitiable. The diagnosis, when eczema has lasted long, may present some diffi- cxilty, and yet is of great importance ; but fortunately it can always be arrived at by a careful inspection of the outer parts of the diseased sur- face. The centre may be converted into a cracked, bleeding, and even suppurating mass, but the circumference will exhibit the characteristic appearances of eczema. It is, of course, not uncommon to have an eczematous rash suiTOunding any affection of the vulva; but the gradual shading of the outer into the inner parts, and the absence of signs of syphilis or cancer, will prevent mistakes in diag-nosis. When eczema occurs on the pubes, abdomen, or thighs, there are occasionally the same difficulties that meet us in other regions in distinguishing it from lichen or impetigo. Fortxmately, they are frequently difficulties of nomenclature rather than of any more important nature. The treatment of eczema, when developed to any extent in these regions, is often most diflicult ; and the tendency to recurrence or TREATMENT OF ECZEMA PARASITES. 3^ exacerbation is most exasperating, but patience on the part of doctot and patient is ultimately followed by success. The existence of diabetes as a frequent cause should not be overlooked. Above all things, con- stant attention to cleanliness is required. Simple soap and water can do wonders here, as in so many other affections, but the soap must be of the blandest kind that can be procured. Premising that we insist on at least two or three ablutions daily, and more if there is any free vaginal discharge, there are innumerable local remedies recommended for eczema in works on Dermatology, to which I must refer my readers. Here I will mention only those which have especially commended themselves to myself, or to others engaged in the practice of gynaecology. Whatever applications are used, any adherent crusts must first be removed by bathing, poulticing, and softening with olive oil. Lime water applied warm will often aiford the relief which alkalies generally do in eczema elsewhere. Solutions of opium, moi'phia, or belladona may be added to any of the following local applications. Dilute hydrocyanic acid (TTlv.-x. ad 5i.) is also highly comforting to the patient. The glycerole of acetate of lead (gr. x.-xx. ad Si.) will often in a very short time produce a satisfactory change in the appear- ance of the rash, and should have a foremost trial ; any of the glyceroles used should be carefully painted on the surface with a soft brush. Zinc ointment, made with vaseline instead of lard, is another useful and soothing application ; or, still better, Zinci oleat., 5i. ad vaselin. alb. Sii. Oil of stavesacre (1 pt. in 8 of vaseline) has been lughly recommended, but is apt to be too irritating in many cases ; it is of more use in the itching of pruritus. When there is much inflammation surrounding the parts, demulcent lotions, not too thick, of slippery elm or marsh mallow, must prepare the way for more active remedies. One could, of coarse, fill a page with the mere names of remedies which have from time to time been lauded, but the following must suffice : — Vaseline simply ; the glyceroles of the following : tar, boracic acid, carbolic acid (weak) ; salicylic acid ; the oleate of lead or of zinc, diluted as above ; chloral (3ss. - 3i. ad oi. glycerimc) and unguentum acid, chrysophanic. 5ss. ad 5i. It need hardly be said that the same attempt, as in other forms of eczema, must be made to reach any con- stitutional causes by tonics, arsenic, anti-rheumatic or anti-arthritic I'emedics, &c. Parasites — tlic acarus scabici, and the various forms of lice — are not infrequently met with, especially in old people. One form — the pedi- culus pubis — by no means confined to the aged, makes this part its especial seat, and partially buries itself beneath the cuticle. The result of any of these parasites is to produce itching, and they will be referred to again when speaking of pruritus. The pcdieuliis ]iiil)is is speedily 40 WAETS, BOILS, CEDEMA, AIv^D PEUEITUS. destroyed by any mercurial, 3 or 4 grs. of bichloride in the ounce of water being the cleanest. Warts. — Simple warts, independently of gonorrhoea, are occasionally found on the vulva, but they are then usually an indication of great want of cleanliness. The remedy lies in the use of scissors and the refoi-m of the personal habits. Gonoi-rhoeal warts will yield to cleanliness and an occasional touch with the concentrated solution of permanganate of potash or tincture of iodine, or they must be clipped off. Boils. — True furu.ncles are apt to occur on the external genitals. As elsewhere, they not infrequently depend on the inflammation set up in a hair follicle by the avulsion of its hair ; they are occasionally also developed within a spot of acne, spreading from it into the connec- tive tissue. Although poulticing gives relief, there is the usual danger of its spreading the disease to other hair follicles or scratches. Tincture of iodine applied at once seems sometimes to aiTest them, and failing that, a paste of chalk and oil freely saturated with carbolic acid or eucalyptus seems to prevent undiie suppuration. (Edema of the vulva occurs in connection with dropsy of the lower extremities. It is also met with during pregnancy, and, when great, should alwaj^s lead to suspicion of renal disease, and an examination of the urine. During the occun'ence of vulvitis or vaginitis, it is also not infrequently encountered ; and I mention this here especially because some authorities have looked upon oedema of the labia under these cir- cumstances as affording a diagnostic point between gonorrhoeal and simple inflammation. I am satisfied that it occurs more frequently in the former ; but I would strongly advise that too much importance should not be attached to the circumstance, especially when character or any legal decision is at stake. Pruritus. — I have included this among the affections of the vulva, — not as a special skin disease, described by Willan and his followers as prurigo, — but considering it to be, like pruritus ani, a mere symptom, depending on a great variety of causes, though in individual cases the search for the cause is sometimes completely baffled. It is met with at all ages, though most frequently, in extreme degrees, in the old. All that has been said with regard to the misery produced by eczema is applicable to pruritus in a still greater degree ; and the two things are not in- frequently met with together, as cause and effect, or as mutual effects of some other affection, but they should not be confoimded. It should be clearly understood that pruritus may exist, and that for years, with- out the appearance of any eruption of the parts affected. I had such a case in a yoimg lady in whom I tried every remedy that I could f the vaginal wall. Local astringent 42 TEEATMENT OF PRUEITUS. lotions or pessaries, strychnine, or other nerve tonics, and careful atten- tion to the wants of nature are indicated, and the catheter may be temporarily required until a healthier state of the external parts is brought about (see Chap. XXI.). In every case of continuous pruritus the urine should be carefully examined, and sometimes a very little attention to the correction of common abnormalities will be followed by good results. But the state of diabetes mellitus especially produces some of the most troublesome cases of pruritus, and that even in instances where the urine is not materially increased in quantity. Nervoiis erythism is much increased in diabetes, but it would appear to be the saccharine urine which is chiefly at fault, not only by its irritating crystals, but doubtless on account of some degree of fermentation. Add to this the tendency to eczema which it induces, not only locally, but in other parts of the body, and we have no want of causation for diabetic pruritiis. Frequent tepid sjTinging and bathing are the chief resources, and, in aggravated cases, tlie use of the catheter may be required if the urethra is not too tender. The possibility of the existence of external parasites, especially of the pediculus pubis or vestimenti, or of the acarus scabiei, must not be for- gotten. The bichloride of mercury solution will speedily destroy the former source of trouble, but in some old people there is a strong ten- dency to recurrent attacks. Scabies must be treated by sulphur or car- bolic acid in the form of ointment. Ascarides may act by mere reflex irritation conveyed to the superficial nerves, but they may pass into the vagina and vulva, and thus become more direct agents. Infusion of quassia, lime-water, or iron (T. ferr. perchlor., §ss. ad Oi.) injected into the rectum will get rid of these. The vagina itself often harbours the oidium, leptothrix, trichomonas, and various infusoria, which are doubt- less highly irritating, and nearly all the specific remedies which have a reputation in pruritus are antiseptics or parasiticides. Occasionally the presence of stunted or broken hairs around the margin of the vulva has been noted as a cause. Such cases are hardly of frequent occurrence, but would, when recognised, demand the administration of aneesthetics and the careful and complete epilation of all offending hairs. Eczema, lichen, and other eruptions are frequently accompanied by an amount of itching out of all proportion to their extent or severity, and this- symptom, as pruritus, may precede or succeed this appearance. Their treatment has already been referred to. Pregnancy is frequently accompanied by very distressing pruritus, and this may be due either to irritating discharge, to the swollen and varicose state of the pudenda so often produced by it, or to a simple hyper- asthetic state similar to that produced in other organs. Tepid bathing, and syringing with one or other of the lotions given below, and atten- TEEATMENT OF I'itUEITU.S. 43 tion to the bowels, or the vise of an abdominal belt to diminish engorge- ment of the pelvic viscera, are the suitable precautions. Occasionally the menstrual discharge is peculiarly irritating, and gives rise to tem- porary pruritus. I know of no Avay of altering this, or the similar con- dition in pregnancy, by internal remedies ; tepid syringing is the only resource. Chronic metritis is a frequent cause, by the irritation of its discharges ; but, independently of that, it and uterine displacements, and even fibroid tumours, are sometimes the causes, much as pregnancy is, by their effect on the pelvic circulation, or by reflex irritation. A careful examination for recognisable disease of the uterus or its appendages, and corresponding treatment, must therefore precede all but the most simple attempts to cure pruritus. We cannot enter here into the subject of the various diathetic diseases. Gout, or those general states which are recog- nised as belonging to the same class, may be suspected, as in so many other neuroses and skin affections, if there is a family history pointing to it, and its antidotes, medicinal, dietetic, and hydro-therapeutic, may be tried. Do what we will, however, to place the treatment of pruritus on a certain basis by ascertaining its causes, we are driven sometimes, as with jaundice, or dropsy, or menstrual disorders, which are but symptoms, to fall back on piire empiricism. Bromides, chloral, or even opiates in- ternally have their place, but the two latter should only be \ised under a sense of deep responsibility. Everything that is included in the widest definition of tonic treatment is generally in the right direction, and a list of only a few of the local remedies that have been used empirically must conclude these therapeutic suggestions. Some of these will be found useful, even while attempts are being made to get at the disease by removing its cause. For vaginal injections the following sub- stances are recommended, and they may be combined when their chemical nature will allow. The figure attached to each of the first five refers to the quantity to be used per ounce :- — Ac. carbolic, gr. x. and upwards. Liq. plumbi acetat., 5ss. Acid, boracic, ad sat. Acid, hydrocyanic, dil., TTlx. Sulplio-carbolatc of zinc, gv. x. Tobacco I have never used, but it is reconnHonded by many — one drachm in- fused in a pint of water. Borax ad. sat., and sulphurous acid 5i- ad 5!. Glycerine is in some cases found too irritating as a solvent for outward apidica- tions ; when that is found to be the ease, olive oil must be substituted, ami all the above substances may thus be applied to the itching surface fre- quently during the day. Mercurial l(;tions, such as black wash, or a ](jtiou of bichloride (if 44 SYPHILIS CONDYLOMA. mercury and hydrocyanic acid, or chloroform (1 pt. to 10 of olive oil), and 01. Staphisag. ^i. ad. vas. alb. §i., may be added to our list of local applications, which might be almost indefinitely extended, but those substances now named are the most reliable. Syphilis. Few cases of primary syphilis come under the notice of the gynaecologist, nd in general practice, while secondary forms of the disease are by no means rare, primary affections are \incommon in the female. We will therefore follow the example of most writers on gynaecology, and leave those more conversant with the subject to discuss the various forms of chancre, their supposed duality of type, and the like questions concerning them. Even the special syphilologist sees the primary chancre much less frequently in woman than in man ; it has most frequently healed before the case comes under his notice. The site is rarely on the cervix uteri, where it could easily be seen by the speculum. Amid the folds or rugse of the vagina detection is often very difficult, and when a hard chancre occurs on the vulva, it frequently resembles so much to the patient a spot of acne that she waits complacently for its disappearance. The sore may even be at a considerable distance from the vulva, on the mons veneris or thigh — the infectious matter having reached the seat of a scratch or a pimple, or a torn hair follicle. There should seldom be any great difficulty in deciding on the diagnosis of a primai'y chancre when it is seen. Lupus or cancer might for a time be mistaken for the small cup- shaped ulcer with its hardened base, or for the more widely ulcerating or phagedsenic form. But the progress is essentially different ; the soft chancre is frequently multiple, whereas cancer springs usually from one centre, and in case of necessity we can fall back on the test by inocula- tion. A due knowledge of chancre as it occurs in the male, and a little of that mother-wit which is required in all cases where there are motives for concealment, should avoid error. The possible influence of the syphilitic dj'scrasia on all chronic affec- tions, especially those of a hypertrophic character, mxist ever be borne in mind in every branch of practice, and especially by the gynaecologist. Condyloma, or mucous tubercle, is a form of soft flattened warty excrescence without pedicle, met with especially in Avomen of un- cleanly habits. These growths are of a reddish-grey colour, varying according to the amount of their vascularity. Microscopically they are very similar to warts, but less firm in texture — more pajiillary, less fibrous. They may exist as small separate patches, or sprout over the whole vulva, and invade the surrounding skin. Opinions differ as to whether they are always specific ; but setting aside one or two cases TREATMENT OF SECONDAKY AND TEUTIAKY .SVI^HILIS. 45 which might be more properly described as soft warts, I have never seen one where I had any doubt as to its real syphilitic charactei*. Gonorrhoea or uncleanliness will cause warts ; they will also materially aggi-avate, but not alone cause condylomata. These growths are also undoubtedly infectious to the male, probably a much more frequent source of infection than the primary chancre, and I think I can say with almost positive certainty that I have seen both w^hat is termed a hard infecting and a soft non-infecting chancre derived from this source. Considering the strongly infecting properties of these growths, it is astonishing how rapidly curable they are in the majority of cases. Soap and water, liberally and frequently used, act almost like a charm. A little calomel and oxide of zinc, in equal parts, carefully applied to the surface, will usually complete the cure in a very short time. But the constitutional disease is still existent, and must be met by antis}^hilitic treatment, or the affection speedily returns. I may ven- ture here to express my own opinion as to the relative value of iodine and merciiry in the treatment of secondary or even tertiary syphilis, as we meet with it now-a-days. Commencing practice as a pupil of Syme and Hughes Bennett, I Avas opposed to the use of mercury, and thought that I could easily demonstrate the efficiency of a non-merciirial treat- ment. The patients got well, but being for some years in a more or less general practice, I was able to trace their subsequent career, and I had ample evidence that the dyscrasia was left more untouched than in those who were treated by mercury in small and long-continued doses. In secondary, and still more in tertiary syphilis, iodide of potassium in full doses will certainly often produce the most immediate and striking- results, a very important matter when brain or other delicate tissues are involved ; bvit permanent results are still more thoroughly attained by small and long-continued doses of mercury, combined with quinine and iron. In very obstinate cases of condyloma the application of strong escharotics, such as nitric acid, acid nitrate of mercury, or the actual cautery, may be required, but such cases must be very rare. The true condylomata are too extended in their attachments to be amenable to excision by scissors, therein differing from simple warts, which have a firmer basis of connective tissue, constituting more or less of a distinct pedicle. Cancer. Cancer of the vidva almost invariably assumes the form of ei)ithelioma. Other forms when met with are nearly always extensions from the parts above. The clitoi'is is perhaps the most common site of commencement 40 CANCER OF THE VULVA. the disease spreading theuce to the njinphae or labia majora, but it may orio-inate in any part. The first phenomenon is that of a small in'itable tubercle which ulcerates in a very short time. There may be an attempt at scabbing, but in spite of this the sore rapidly extends, and the thick indurated edge, hanging over the angry advancing ulcer, is most diag- nostic. When commencing on the inside of the labia, there is sometimes at the fii-st a condition of the mucous membrane which might be mis- taken for o-ranular or follicular inflammation. There is, however, an indurated base underneath, and after a short time true ulceration shows itself. This form usually occurs in elderly women, and I have kno^Ti it treated for a considerable time as vulvitis or vaginitis. Another form, consistino- of a sort of cauliflower excresence of the labium, with free watery discharge, is occasionally found in old, feeble, women, and has been named " oozing timiour of the labium." In all forms the inguinal and pelvic glands become speedily affected. Continuous pain, hsemo- rrhagic and foetid watery discharges, in time lead to the death of the patient, but this is more often due to the secondary invasions elsewhere and to the general cachexia thus resulting. Treatment, to be of any use, must follow immediately and energetically •on diagnosis. Excision of the whole diseased smface, whenever there is the remotest chance of reaching healthy tissue, must be performed, and the patient should have the benefit of any doubt that may exist on the point. The knife is attended with considerable risk of hsemoiThage, which, though it may he arrested by styptics and pressure, diminishes the already faihng strength of the patient. Chain or ^nre ecraseiu's are too clumsy, and the shai-p cutting heated platinmix wire of the galvanic cautery (fig. 56) is by far the most efficient instmment. The heated knife of a Paquelin's caiitery (fig. 57) is also very effective in excision of such parts. The local application of bromine (1 part in 5 of spirit) or of nitrate of mercury, or of salicylic acid and collodion (3i. ad §i.) may for a time arrest progress and give temporary relief, but in any case where there is the faintest hope of cure or of any long suspension of activity, excision by the cautery knife or ecraseur is to be performed. Lupus {Esthiomeoie). Lupus of the external organs of generation is hardly so common as the same disease affecting the face. It occurs in badly nourished strmnous women, generally between the ages of twenty and thirty. Without attempting here to discuss its pathology, it has always appeared to me to be one of those affections whose careful study would serve to throw lio-ht on the evolution of disease, so gracefully discussed by Sir LUPUS AXD Is^OMA. 47 James Paget in the first Bradshaw lecture. Its resemblance, and also its dissimilarities to syphilis, scrofula, and epithelial cancer, point to a possible intermediate stage in development. The majority of writers, however, consider it to be only a manifestation of scrofula. Clinically we have a sore which alternately ulcerates and heals, creeping around the vulva, and leaving a depressed white scar to mai'k each step in its continu- ■ous progress. The sores are preceded by flattish discoloured tubercles, which are often very slow in ulcerating. As a rule, there is not much pain. Progress, though slow, is only too sure, and large tracts are covered with cicatricial contracted tissues before the disease comes to an end, if it does so during the life of the patient. As regards treatment, tonics, cod-liver oil, iodine, and arsenic appear, under good hygienic conditions, to exert a somewhat favourable influ- ence. They tend to induce, and may perpetuate, the cicatricial stage. Though removal by galvanic cautery, or by the most powerful escharotics, •often fails to aiTest progress, yet it may temporarily check the disease, and give time for constitutional treatment. Of late years, most success- ful results have been obtained by Volkmann, Yeats, and others, by thoroughly scraping off the surface, but I have as yet had no experience of this in lupus of the vulva. Should the cicatrices threaten to occlude the canal, the frequent passage of a large bougie may to some extent •obviate this danger. Noma. Under this name has been described a gangrenous condition which, as Si sequel of the zymotic diseases, or of the septic or pysemic puerperal affections, or as a manifestation of ejoidemic or spoi'adic erysipelas, some- times attacks the external parts of generation, as it may also do the face. Dr Hermann records some cases of each kind in the Ohstetrical Trans- actions, vol. XXV. p. 141. It seems to be a mistake to have given the this affection special name. It is simply gangrene, a sign of low vitality and embolic changes. Antiseptic poultices and liberal nutrition, with wine, as it may be thought desirable, are oiu- only resource. If sufficient vitality can be maintained to permit of separation of the slough before .a vital part is reached, the patient may be saved. Vulvitis. The vulva is not infrequently the seat of acute inflammation, and this may either be simply catarrhal, from cold or injury, or it may ensue from the spreading of va inal inflajnmation downwards, or it may be 48 VULVITIS. gonorrhceal. In each case the symptoms present so much similarity that it is most difficult by these alone to diagnose between the specific and non-specific cases. General redness of surface, with perhaps temporary dryness, heat, tingling, itching, and smarting, speedily followed by swelling and profuse muco-purulent or purulent discharge, constitute the common symptoms. In the adult the acute cases are mostly gonorrhceal, and there are a few points which, though separately insufficient to prove anjrthing, by their combination, render the diagnosis of gonorrhoea moderately certain. Great acuteness and suddenness of onset, the absence of other recognisable causes, much scalding urination, the presence of pus in the urethra, ascertained by forward pressure with the finger, and oedema of the labia as before mentioned, are character- istic of the specific form, while a more free admixture of mucus with the pus points rather to the other. Additional aids to diagnosis are the foetor of the discharge in the specific form ; its transmission -to the male (which may, however, occur in the simple form) ; the greater frequency of abscess of the vulvo-vaginal glands, and of buboes. But no matter how convinced the practitioner may feel, these symp- toms will never justify him in asserting that he has positive proof of gonorrhoea when such a statement must be held as evidence of un- chastity. As an occasional cause of acute, sub-acute, or chronic vulvitis, we may also note irritating vaginal or other discharges. Nearly every one of those circumstances mentioned at page 41 as among the occasional causes of pruritus may also induce vulvitis. Viilvitis is not infrequently met with in young children or even infants, and here there is a necessity for still greater caution. Want of cleanliness alone will suffice to produce the affection, so may injuries of a perfectly innocent character, so may the presence of ascarides, though Matthews Duncan throws doubt on this, and in scarlatina or other zymotic diseases, rather acute vulvitis sometimes occurs. Let the young practitioner beware of such cases, and remember, that however circumstantial the accounts of criminal assault given by the young patient herself, or, at second hand, by her friends, purulent vulvitis is no proof of such assaults, and has most commonly nothing to do with them. The evidence derivable from injury to the perineum, y the author. (.\.) handle, with a large well-bevelled eye near its point (fig. 42). This and its suture wires will be found amply sufficient for the perfonnance of the primary operation, unless in the case of great tearing of the septum. It is much more satisfactory to place the patient on her back than to be satisfied with the left lateral position, and she must be brought to the ^dge of the bed in as good a light as possible. Anassthesia may be used if she is very excitable, and if the uterus is well contracted, but owing to numbness of the parts, caused by the previous perineal stretching, there is usually less pain from the operation than might be expected. A good nurse will contrive to hold up and separate both knees, while the nates and feet rest on the edge of the bed, but a second assistant is very servicable, or the hand and foot of the same side may be tied togetlier. The operator, however, must depend on himself for all else but retaining the patient in this position. The whole torn surface is first wiped as clean as possible, and any extensive bleeding is arrested by pressure or the application of a little carbolised spirit. A piece of clean sponge or 64 PERIXEOKKAPHY. linen is then pushed into the vagina, past the tear, so as to keep back the lochial discharge. This must be removed after the sutures are placed, and before they arc tightened. All this, like every other ob- stetric proceeding, should be rendered antiseptic by the free use of carbolic solution. The left forefinger of the operator is now placed within the vagina, ready to receive and guide the point of the needle. This is inserted on either side first, without wire, fully half an inch external to the torn surface of skin and a little behind its posterior end, and is pushed through the intervening muscular tissues to the extreme pos- terior end of the wound in the mucous wall. A good amount of mus- cular tissue is thus incKided between the rent and the track of the Fig. 43. — Introductiun of First Suture, with Straight Needle, in immediate Perineorraphy. needle, and this is much better done by a straight than by a curved one. The point should emerge as nearly as possible exactly at the torn edge of the mucous membrane. If much of this is included, it will form, by its inversion, when the ligature is tied, an impediment to union, and if it be not caught at all, a raw surface will remain above the suture, a possible source of septicsomia. The eyelet of the needle, guided and guarded by the left finger, is pushed fairly through into the vagina, and threaded there with one of the sections of wire. If the needle is pro- perly made, and the wire is of due thickness, this is easily accomplished, either by sight, or by touch alone if the patient is stout or muscular. Bending back an inch of the wire, the needle is withdrawn, and so draws PEKINEOERAPHY. 65 dowai the suture ou one side. Precisely the same thing is now done on the opposite side, the needle withdrawing, in its track from the vagina, the other end of the wire (fig. 43). Two, three, or four other sutures are similarly passed in front of this, at equal -distances, the foremost being close to the apex of the perineum. The vaginal plug is then withdrawn and the wound again carefully sponged with carbolic solution, cold at this stage, until all bleeding ceases. The stitches must now be tightened, and one pair after another gradually drawn until a finger in the vagina assures tis that there is an even surface on the mucous side of the wound. Simple twisting of the opposite wires is all that is necessary, and shot or other clamps are, in the primary operation at any rate, a needless complica- FiG. 44. — Quilled Suture of Perineum (Baker Browu). tion. The line must be di-awn at that amount of tightness which ensures- very slight traction on the whole wire, allowing for some subsequent swelling of the parts and easy adaptation of the torn surfaces, without forcible sqxieezing of the intervening parts. The wires must be taut, not tight. The twisted ends arc cut off a full half inch from the surface and laid flatly on the sides of the wound. If care has been taken, an inter- rupted suture or two of gut, at gaping points, should be unnecessary. The after-treatment should consist of catheterism, careful^ antiseptic ablution, light nourishing food, and the other steps afterwards more fully described when speaking of the management of vaginal or i: ■66 THE PEIMAEY OPEEATIOJ^T. uterine operations in general (Chap. III.). The stitches may be allowed to remain for about eight days. The patient should lie mostly on her side, right and left alternately. Post-puei-peral exigencies may occa- -sionally require us to depart from the usual dietetic rules. The ques- tion of locking up the bowels for a considerable time, after this and other operations on the perineum, is a difficult one. The immediate advantage of doing so is self-apparent, but the subsequent risk from the passage of large hardened masses, which forcibly distend the recently united stiiictm-es, must have also occun-ed to every operator. On the whole, I am inchned to agree with my colleague, Dr Cullingworth (see paper in Mediad Chronicle, November 1884), that it is advisable to leave matters very much in the hands of nature. In venturing to propose this as the simplest and most satisfactory method of operating primarily on the torn perineiun, I am aware that many still prefer the double or quilled suture, introduced by curved needles, and fastened at either side over pieces of quill, catheter, or ivory. This (fig. 44) is famihar as "Baker Bro-\vn's " method. The single wire is more simple, and quite as effective, and much havoc may be played with the soft parts, in stout patients, by forcing needles, often with shai'p edges, around the necessarily large and sweeping curve. If the tear has completely divided the perineum and gone through the sphincter ani, the operation just described will yet sufl&ce, unless the recto-vaginal septum is ve^'y much affected. The perineal stnictiu'es being restored to their natural position, and firmly held there by the sutures, the torn septtmi is thereby placed with its edges in juxtaposition. But it is often desirable in such cases to apply one or more sutm-es to the septum itself, though, if the rupture be very gTeat, subsequent proceed- ings will probably be required. The best material for these sutures is gut, which may, after insertion, be left to take care of itself. One straight needle, or much better, a small curved one held in a needle-holder, is armed with a gut ligature, and thus passed into the vagina, before any- thing is done to the perineum. A finger of the left hand in the rectum is the guide, and the sense of touch must often replace that of sight. One or more sutures are thus passed through the opposite edges of the torn septum, including only a small portion of its substance, and their ends are tied and cut short within the vagina. The perineal operation is then performed. The more elaborate proceedings recommended for the secondary operation are almost always impossible in primary cases, and I suspect that some of our eminent siu'geons, who recommend and practice these, have had little or no experience of the Ijing-in room, especially among those classes which, in England at any rate, seem to furnish the great majority of such cases. THE SECOXDAEY OPEKATIOX. 67 The secondary operation is, iu one sense, little different from, the prim- ary. It aims at precisely the same object, viz., the bringing together of the opposite raw surfaces by suture ; but it requires to have its raw svir- faces made afresh, and it is conducted under very diflFerent and more favourable surroundings. A choice of time, and a choice of operator are open. There is no excuse for the want of sufficient light, or of assistance, or of anj-thing else that is requisite to ensure success. As in the case of the primary operation, it may be necessary to repair only the perineal substance, or the torn recto-vaginal septum also. The operator, under the conditions of the secondary operation, has another great advantage ; he may, if he think it advisable, as he often will, repair the torn recto- vaginal septum first, and at a subsequent operation proceed to the repair of the perineum. At least four assistants are necessary, or at any rate useful, to perform these operations with certainty and comfort. One of these takes care of the ansesthetic, and two suppoi't the legs of the patient. To do this satisfactorily, she is placed in lithotomy position, the hand and foot of the same side being tied together. One assistant stands on each side, facing the operator, and with one arm keeps the knee of the patient well abducted, while with the other hands they hold open the labia, taking care to keep them exactly in the same position on each side, and making no irregTdar traction in any direction. Small spatuke are more convenient for this purpose than the fingers. The fourth assistant is prepared to assist the operator with sponges, &c., and must be careful in Fig. 45. — Sim.s's Sponge-holder. Fig. 46. — Emmet's Knife-holder. doing so not to obstruct the light. To avoid this the sponge^ should be small and held by forceps or special holders (fig. 45). The recto-vaginal septum, if torn, is first attacked, and, as has been stated, this may often suffice for one operation, where the rent is severe. The opposite edges are to be freshened down to the sphincter, the operator seizing fii*st one and then the other with a fine hook or forceps, and carefully cutting it away. The strips should be removed from the vaginal, rather than from the rectal wall. For this purpose cither a fine long-handled bistoury may be used, or one capable of being set at any angle to its handle (fig. 46), as introduced by Sims for operations on the cei*vix uteri ; but the majority 68 VAEIOUS INSTRUMENTS. of operators will succeed best by using scissors, curved or straight, as may seem most convenient (fig. 47). Those who practise surgery of this kind to any extent will find it necessary to have several pairs curved in various ways. Only a thin strip is required, and its removal is a very dehcate process. As far as possible it is well to remove the whole of one side in one strip, and no islets must be left behind. To ensure the Fig. 47. — Bozemann's Scissors. apposition of raw edges at the upper angle, it is well to lengthen the tear with the scissors for an eighth of an inch or thereabouts. The septum operated upon is so thin that its certainty of adhesion is increased by very carefully separating its two layers, or splitting it to a slight extent, and this, quite independently of any relation to modifi- FiG. 48.— Laterally Curved Needle, for fistula, &c. cations where the slitting is made more thorough, and the vaginal and rectal portions treated separately. Su.tures have now to be apphed— gut when the perineal operation is performed at the same time, silver when it is not. A finer wire is advisable than that used for the thick perineal body. The needle for this purpose must curve laterally in relation to Fig. 49.— Tyler Smith's Tubular Needle. its holder, whether that be free or attached(fig. 48) ; all forms of tubular instmrnent (fig. 49) are apt to get out of order, and the handled needles are seldom sufficiently round and free from cutting edges. About five sutures are required to the inch ; those of gut are tied in the vagina and SECONDARY PEKINEOEEAPIIY. 69 cut short ; those of silver are twisted, and cut off a full half-inch from the mucous membrane, and the stumps are bent over to the right and left sides alternately, to facilitate removal. For the repair of the perineum, a freshening process is required on a larger scale than would at first suggest itself. Two raw surfaces are required, to represent, as nearly as possible, the torn perineal sides, and as the parts have now shrunk, the freshening must extend somewhat into the buttock and vagina, and beyond the new, glazed mucous membrane. We form therefore such a raw surface as represented at fig. 50. The dissection should commence behind, and should first outline the posterior border of the new perineum, then gradually work- ing forwards, a layer of the requisite size and shape is dissected ofi^ on either side. If the dissection were commenced in front, the blood, trick- FlG. Perineum Fresliened, witli Sutures introduced. ling backwards, would greatly obscure the subsequent progress. I have seen the proposed outlines of the dissection previously mapped out with a pencil of nitrate of silver, but it is better to depend on one's observa- tion at the time of operation. The two sides must, however, be vivified as nearly alike as is possible. Many, if not most, operators prefer to denude the proposed surface by snipping with fine scissors rather than by the knife. All bleeding must be stopped by pressure and torsion of the most vascular points ; and continuous oozing, by cold, or by a fine stream of hot water, or by the use of si)irit of wine. A totally different plan of revivifying was proposed by Dr Jeuks of Chicago in the Amerinui Journal of OhstetricK for April 1879, p. 262, and has been tried with success by Emmet, Albert Smith, and others. 70 SECONDARY PEEIXEOEEAPHY. He first makes a small incision with fine scissors, about the centre of the lower border of the proposed raw surface. Through this both blades are insinuated, below and parallel to the mucous siuface, and its separation is now performed subcutaneously by repeated snippings. Discoloration of the smface clearly marks the route the scissors have taken, but there is no external haemorrhage, except a few drops from the opening, and the process is rapid. When the whole required surface is thus separated from its attachments, and clearly indicated to the eye, the flaps are cut away on each side by scissors, with perfect regularity of outhne, and there is no necessity for searching for islets of mucous tissue not separated. I look upon this plan as a most valuable contribution to g}Ti8ecological surgery, and it can be made equally available for those modifications of the operation, where the flaps of mucous mem- brane are, instead of being cut away, utilised, by their apposition, to increase the strength and thickness of the perineum. A probe-pointed tenotomy knife can be introduced, and used in the same w-ay as the scissors, but is more likely to give rise to some troublesome hsemorrhage afterwards. When the freshening is completed by the removal of the necessary surface, and oozing has ceased, the sides are brought together precisely as in the primary operation. The straight needle and silver Avire will in most cases suf&ce equally well in the secondary operation, if care be taken to place the posterior stitch quite up to the posterior angle of the woimd in the vaginal mucous wall. If there is still a small portion of imunited recto-vaginal septum, which has, however, been well freshened, many authorities recommend the use of one posterior stitch, which would certainly requu'e a long and well-ciu'ved needle for its in- sertion. The course of this stitch is as follows : — Entering on one side, half an inch at least external to the lower margin of the amis, it passes, guided by a finger in the rectum, through the muscular tissues, into the cellular tissue between rectiim and vagina, round and above the upper edge of the rent, without emerging, and so downwards on the opposite side. This stitch, if used at all, must be inserted before those in the perineum, and it must be clamped at each extremity, rather than tied, so as not to occlude the anus. The proceeding now given is the one which seems to me to be, on the whole, most capable of yielding good success, in the hands of an operator endowed with a fair ordinary amount of skill. But there are very many modifications, some of which are, I believe, improvements, especially in the hands of the dexterous surgeons by whom they are introduced ; others are, I am sm-e, unnecessary com- plications. In Baker Brown's Surgical Diseases of Women, 1866, the student will find the basis of these operations most carefully laid, the EMMET ON PEKINEORIIAPHY. 7 1 improvements which have since been chiefly of advantage being the introduction of silver wire for ligatures, and the abandonment of the double or quilled suture. A great number of the proposed alterations have also for their object to avoid the removal of any part of the tissues, and instead of entirely removing the dissected flaps, to utilise them for the purpose of closing the rent and rendering its adhesion stronger. This is accomplished by turning them upwards into the vagina and uniting their raw surfaces. The coxcomb-like projection thus formed soon shrinks. In Emmet's Principles and Practice of Gynmcology, (1880), the student will find much recent information on perineorraphy as on all surgical questions in gynaecology. In Schroeder {Ziemssen's Cyclopcedia, vol. x.) he will find a short description of Langenbeck's and Simon's methods. Lawson Tait's ingenious procedure for utilis- ing the flaps {Obstetrical Journal, vol. vii.) I ' have known produce excellent results, but it is not every tyro who will clearly understand it, unless he sees it actually performed. Bantock {Rupture of Female Perineum, 1878) conveys much useful information, and Goodell {Lessons in Gynecology, 1880), in his racy manner, gives much sound practical advice on the subject of perineal repair. No one would, I suppose, undertake the management of a delicate case of this kind without care- fully studying one or more such authorities. It is characteristic, however, of the fluctuating condition of much of gynaecological surgery, to find Emmet recently stating (I quote only from an abstract in the American Journal of Obstetrics, vol. xvi. 1883, p. 1080), that "a simple laceration of the perineum, extending even to the fibres of the sphincter ani, produces no inconvenience after the ]Darts once have healed." Until the inutility of operations for the cure of ills, believed to be due to this cause, is further proved, and the necessity for other or additional oj)erations on the posterior vaginal wall is a little further worked out, I must consider this matter as at least sub Judice. I am, however, certain of this, that although the pelvic fascia, which is per- forated by the vagina and urethra, may be probably shown to furnish the chief outward support for the pelvic viscera, rather than the perineal body, and although it may be the case that this fascia can only be restored to action by paring and stitching together some portion of the posterior vaginal wall, higher than any perineal tear, still the absence of the peri- neal body does, by itself, promote vaginal prolapse, usually followed by uterine descent. We shall therefore remain indebted to Ennnet and others for the care they have bestowed in i)erfecting its repair. 72 insteujVIents used in gynecological teeatment. CHAPTER III. Methods akd Meaxs commonly employed in Surgical Treatment. Instru- ments used in Local Treatment. Methods of Introducing Eemedial Substances. General Management of Gynecological Operations. Preparation. Anti- septics. After-Treatment. Anesthesia. In speaking of the after-treatment of the operations for torn perineum, at the close of the last chapter, I referred to the present for some further details. It would seem that a good deal of unnecessary repeti- tion may be avoided, if, in this section, I introduce a few somewhat discursive remarks on several of the means and methods employed in the surgical treatment of female diseases. Many means of the kind are only applicable to a small number of cases, and only intelligible when these are under consideration. Others have a more general application, and these I propose to mention here. Certain Instruments nsed in Treatment. 1. Aspirators. — Both for diag-nosis and treatment, an aspirator, in some form, is very commonly required. For the former purpose it may be necessary to remove only an exceedingly small quantity of fluid for examination, or perhaps merely to ascertain whether there is any fluid to remove ; and in such cases the ordinary subcutaneous injection- syringe Avill suffice. If full antiseptic precautions are employed, the use of this may be said to be quite free from danger. In order to reach cysts situated high in the pelvis, or in the abdomen, a much longer tubular needle may be employed, furnished with a stop-cock (fig. 51). I prefer to call this form of aspiration "exploration." In the case of very small cysts, those of the labia or vagina, for instance, even Avhen complete emptying is required, this means may also suffice ; but a larger and more complicated instrament is generally necessary, the essentials of which are a good-sized receiver, a strong, well-fitting exhausting syringe, trocars of various sizes, or needles into which the cutting-point can be withdrawn, and a connecting flexible tube, with one or more stop-cocks. The instrument of Rasmussen (fig. 52) fulfils these conditions, though there are several others of more elaborate make. For the diagnosis of ASPIRATORS ECRASEURS. 73 the coutents of ovarian tumovirs from ascitic fluids, or from the fluid of parovarian, renal, hepatic, mesenteric, or other cysts, the aspirator is frequently necessary. Cystic, or apparently cystic, tumours in the pelvis, containing blood, pus, serum, or ovarian or other fluids, may thus be diagnosed, but puncturing of these by any but the very finest needles is very gravely to be deprecated, unless the surgeon is prepared to act at once upon the knowledge thus obtained. The fluid of an extra-uterine foetation may also be removed by a fine aspira- tor, with a view to arresting the growth of the foetus. Ecraseurs. — The ecraseur is another instrument in fi-e- quent use for the removal of tumours which can be encircled by its wire or chain, especially those growths which have more or less of a pedicle of attachment. It has the advan- tage of performing a bloodless amputation ; it can often be applied where the knife or scissors cannot reach, and, if curved, it often avoids the necessity of dragging the parts too forcibly downwards. On the other hand, its incision is less clearly defined than that of the knife, a matter of importance in malignant disease, and if there be not a well- defined pedicle, it may, as it were, scalp the included growth rather than cut clearly through its attach- ment. In some cases this can be avoided by first transfixing the mass with a needle just outside the bite of the wire or chain (fig. 53). The fol- lowing arc the chief forms : — The chain-ecraseur of Chassaignac (fig. 54) and its modifications ; the wire or wire-rope ecraseur (fig. 55), which may also be curved in its shank ; and the galvanic ecraseur. A smaller form of wire-ecraseur is used by Emmet as a tourniquet to constrict the cervix uteri, and so arrest hajmorrhage dur- ing the performance of operations on Fig. 51.— Aspirator Needle. ,■<. , /-. ^^i o ,-i i that organ. Growths of the vulva or vagina, the cervix uteri itself, polj'pi or polypoid fibroids of the utcnis, whether intra- or extra-uterine, are very frequently removed liy the ecras- eur. The pedicle in ovariotomy is also occasionally divided in this way. The chain-ecraseur has undoubtedly very great power, and is there- fore applicable for the amputation of large or solid growths, when it can 74 ECEASEUES, be made to eucircle them. When they are high up in the uterus this is, however, often very difl&cult, owing to the too great flexi- bihty of the chain. Marion Sims had an ingenious appar- atus for keeping the chain loop open, and guiding it over a bul- bous polypus, but in really difficult cases I have not been able to succeed with it, and the same experience has occurred to others. A whip-cord may be passed roimd by means of such an instrument as Belocq's, used for plugging the posterior nares, or by the old-fashioned Gooch's cannulge, or by two gaim-elastic male catheters, through each of which the ligatui-eis passed, unit- ing them loosely at their further extremities, and by this cord the chain may be dra-mi round the pedicle or base. Even then it may be very difficult after- wards to fix the chain properly so that the ecras- eur will work. The wire instru- ments are rather more simply con- Fig. 52. --Rasmussen's Aspirator. structed, and the wires used vary. The best of all is a well-annealed steel wire, which may be had of any streng-th, and of very great pliability at the same time, and there are few intra- uterine growths over which it cannot be manoeuvred. The wires of many strands are useless for very resisting growths, but Messrs Newall & Co., of 130 Strand, London, manufacture a rope for telegraphic pur- poses, which was first favourably men- ^i*^- ^3.— Gro\mi transfixed by Needle, tioned by Mr BarweU at the London to secure the hold of the Ecraseur. ' Chnical Society. It is very strong and very flexible, superior to the ECEASEUES. 75 single wire in flexibility, but slightly inferior in strength. The ^alvanic Fig. 54. — Chassaigiiac's Chain Ecraseur. Fig. 55.— Braxton Ilicks's Wire Ecraseui'. 76 GALVANIC ECEASEUR AND CAUTEEIES. ecraseur (fig. 56), when its platiimm wire is heated sufl&ciently, cuts through as cleanly as a knife. The wire should, while cold, be tightened just sufficiently to hold firmly, and the screw must afterwards be used very slowly, so that it may burn, not tear through. The least over-tension will break it. It is very important to ascertain before operating that the number of cells is sufiicient to heat the thickness of platinum wire used, and it should be remembered that the heat required is much greater when the wire is surrounded by moist tissues, than when free in the air. The galvanic ecraseur is admirably adapted for growths of the vulva or cervix. It cannot be retained in its place by a vulsellum or metal needle, as the electric current is thus wrongly directed, but a bone needle may be used for the purpose. 3. Galvanic or Thermal Cauteries are of service in many other forms beside that of the ecraseur. Whenever any growth can be de- stroyed by the action of heat, and when there are great or insuperable difiiculties in getting beyond it, the variously shaped instruments which are attached to Paquelin's thermo cautery (fig. 57), or which may be adapted to the galvanic battery, may be used for this purpose, and especially the white-heated blunt knife can be used bloodlessly and safely on re- dundancies of the external genitals, or for open- ing cysts or abscesses. Till Faure's or other accumulators of electricity are placed more freely at the disposal of the profession, Pa- quelin's instrument will be found most useful. I have not attempted to describe the detailed action of either it or the galvano-ecraseur. A few minutes' inspection will be more ser- viceable than any instruction in their absence. 4. Curettes. — The curette is an instrument of comparatively recent introduction, of un- FiG. 56.— Galvanic Ecraseur. doubted service, but capable of being, as it has been, very dangerously abused. Recamier's instiniment, introduced in 1850, was a small steel loop, with a very decidedly sharp scraping CAUTEEIES CURETTES SCARIFICATORS. 77 edge, attached to a stiff handle. Since then it has been advantageously modified by Thomas and others (fig. 58), becoming mei-ely a blunt, though not very thick, wire loop, with a handle which is capable of being slightly bent, while the loop is rigid. Simon uses a cup-shaped scoop of steel, of various shapes and sizes. For diagnostic pur- poses, the curette, introduced through the naturally or artifici- ally dilated cervix, may be em- ployed to scrape small portions from any sufl&ciently soft intra- uterine growth, for microscopic examination ; and it has been freely used by S. Moricke in his investiga- tions of the menstrual mucous membrane. For the removal of chronic intra-uterine, inflammatory granulations, it is also as safe and effectual, in thoroughly practised hands, and none else should use it, as the more powerful caustic fluids, and it is a valuable addition to our means of treating retained and adherent products of abortion. For Fig. 57. — Paqiielin's Cautery. Fig. 58.— Sims's Curette. the removal of intra-uterine malignant growths it is also available, although, as it is impossible to hope for cure in this way, it should only be used in the presence of continued wasting discharge, which we hope for a time to alleviate, and there is always some danger of the portions of diseased tissue thus loosened adding to the rapidity of secondary systemic infiltration. Volkmann's spoon may also occasionally be turned to account in uterine practice. 5. Scarificators. — Depletion of the cervix uteri is sometimes of undoubted advantage. For this purpose, leeches used to be freely cm- ployed, but their application is exceedingly troublesome, and many accidents have followed in its wake — dangerous haemorrhages, scptictcmia, hysterical complications, and escape of the animal into the uterus. Their application is xmsuited, for different reasons, to the practitioner or to the ordinary nurse. Some form of scarification is now, therefore, always preferred, though leeches are still occasionally applied to the perineum, for general engorgement of the pelvic viscera. It matters little whether the scarificator is round, spear, or otherwise shaped ; any cutting instru- ment, with a handle long enough to permit of its use with the speculum, 78 SUTURES AND LIGATUEES. "will suffice (fig. 59). Several radiating cuts are made, about an eighth of an inch deep, which -will bleed freely, though seldom profusely. In acute inflammation of the uterus, or its neighbouring parts, scarification of the cervix often gives considerable rehef Among chronic afl^ections, the chief indications are dysmenorrhoea, prior to acute exacerbations, when these can be reasonably foretold, the occasional sub-acute engorgement of fibroid growths or chronic enlargements of the uterus, sup- pressed menstruation with great pelvic fulness, and chi'onic cervical endometritis with folhcular projections from the cervix, in which case as many as possible of these folhcles should be pimctured. I have no experi- ence of scarifying the interior of the uterus except by curette. The pain of scarification, except under condi- tions of acute inflammation, is only trivial, but the operation should never be performed except at home and in bed. One can never be quite sure of not meeting with a special hsemorrhagic tendency, or wound- ing a varicose vein of the cervix. Incision of the cervix uteri, for the purjDose of enlarg- ing its canal, wiU be spoken of under the headings of Dysmenorrhoea, Uterine Flexions, Fibroid Tumours, &c. Dilatation of the same part by various artificial means, for diag-nostic or therapeutic piu'poses, will also be then discussed. 6. Sutures and Ligatures. — So many gynaecological procedures, slight and of every-day occurrence, or severe and within the range of the speciahst alone, involve the bringing together of torn or artificially freshened parts, that it wiU be well to say a few words on the subject of ligatures and sutures, their material, and mode of introduction and removal. As regards material, owe choice is practically threefold — metal, silk, or gut. Metal Sutures are, for the great majority of purposes, the best, wherever they cannot be left for absorption or other disposal by nature alone, without removal. They can be made, and are in their nature absolutely a-septic. They can be retained with impunity for a very long time. They are, if of right material, as flexible and as strong as <;an possibly be desired. An era in gynsecological surgery commenced when the best foi-m of metal sutures was introduced by Marion Sims, and no kind of metallic suture equals pure, or nearly pure, silver. Galvanised iron wire has some advantages, chiefly on the score of expense ; but the Fig. 59.- Palfrey Scarificator. WIRE SUTURES, THEIR MANAGEMENT. 79 requisite degrees of strength, flexibility, and thickness are not in the market. Silvered or electro-plated wires arc an utter snare and delusion ; they break, or they hank, or they otherwise fail one at the most critical periods of an operation. I advise the general practitioner, even one who will never attempt any plastic operation beyond repairing a recently torn perineum, to insist on his instrument-maker guaranteeing him a few yards of silver wire, toughened, perhaps, by a slight alloy, but not electro-plated rubbish. There are several varieties of thickness which may be employed for different purposes. No. 24 is a strong though flexible Avire, suited for stitching the deep perineal tissues, or for bring- ing together the abdominal walls in abdominal section. No. 28 and No. 30 are more suited for vesico-vaginal operations, or stitching the torn cervix, but occasionally a stouter wire is preferable in this latter case, Avhen the parts are indurated and the gaping is persistent. Silk is also spun of very varying thickness, and the medium sizes are still preferred by some, where the majority prefer silver. If made of silk only, and well carbolised, they are certainly available for such purposes, but not so safe as good wire. Some years ago I tried alternate silk and silver sutures for the abdominal walls in ovariotomy, and I had, in the same cases, several small purulent foci around the former and none about the latter. For the pedicle in ovariotomy the strongest makes of pure China silk answer admirably. Gut Sutures, thoroughly carbolised, may be used for tying small vessels within a closed wound, but torsion should nearly always sufiice for these. There are few who dare trust the ovarian pedicle to them ; but either they or fine silk ligatures do well for small adhesions, and are never heard of more. For deep sutures about the vagina, where it would be almost impossible to reach them for removal, without injuring lower and recently united parts, the gut suture answers well, and in time it entirely disap- pea,rs. Lister's chromic cat-gut ligature lasts a considerable time, where that is desirable, and Ban- tock greatly prefers the so-called silk-worm gut. Gut and silk are tied in the ordinary knot, but wire requires to be twisted or clamped. I think there Fig. 60.— Silver Wire Twisting (Emmet), is a strong tendency to abandon the latter procedure in favour of the former. When the wtniiHl is upon the external surface of the abdomen or ])erineuni, twisting can l)c performed by the fingers alone, as well as by any instruments, — the more nimble the fingers, the more is this true ; but when this has to be done within the vaginal or other cavities, two instruments are useful or even 80 VAGINAL INJECTIONS. essential. One of these is a minute fork (fig. 60), through the slit in which both ends are carefully placed, and shouldered together at the right spot, while the twisting is performed by the other, a broad pair of forceps. Removal is effected by gently lifting the twisted portion, snipping one side close to it, and then drawing the twist slowly over towards the cut side, while the edges of the wound are pressed with the closed scissors. The operator will find many minute and valuable suggestions on the whole subject of sutures in Emmet's Principles and Practice of Gynaecology. Introduction of Eemedial Substances. Vaginal Injections. — Vaginal injections are required either for the purpose of introducing remedial fluids to the walls of the vagina, in the various chronic or acute affections of that organ, for washing away hurtful discharges, or for the effect to be produced upon the surrounding organs and tissues. The various substances — astringent, antiseptic, soothing, or alterative — employed for the first of these indications, will be men- tioned in Chapter V. and elsewhere, but their efficacy is often impaired or entirely destroyed by faulty methods and instruments. The classical clyster-pump of Moliere's time is entirely out of date, and the little glass Fig. 61. — Higginson's Syringe. or pewter instruments sold in the shops are almost absolutely useless. Every vaginal injection-syringe should be furnished with a slightly bulbous, hard caoutchouc nozzle, some five or six inches long, and this should be perforated at its sides, and not at its extremity, otherwise there is a risk of performing an involuntary intra-uterine injection. If well made, the lateral orifices should also perforate the tube obliquely in a backwards direction. Fitted with such a nozzle, there is nothing better for ordinary purposes than Higginson's syringe (fig. 61). If the patient is strong, she can, in ordinary cases, use it herself, and it is very easily managed by an assistant. When frequent or continuous irriga- tion is required, it is better, however, to depend on simple gravitation THE VAGINAL DOUCHE. 81 or syphon action, the fluid being placed at a higher level than the patient, and allowed to gravitate downwards by its own weight. Fig. 62 illus- trates the principle of the vaginal douche, and it requires but little inventive genius to extemporise such an one in the cheapest possible fashion, while much more elaborate forms of the same thing are purchasable. Brass pumps and patent winding-up syphons are quite unnecessary. The position of the patient is of great importance. For simple washing, or mild astringent injections, the semi-sitting posture over a hip-bath, chamber iitensil, or hidet, may answer ; but it is very fatiguing, and fails to allow of the full effect of any remedy. To get the full advantage, the patient must lie on her back, with her hips well raised, so that the fluid gravitates back- wards. Some ingenuity is required to place the bed- pan securely under the hips, and to guard the bed with a w^aterproof sheet so that it does not become w^et or soiled ; and this difficulty may sometimes be avoided by attaching to the tube a double vaginal piece (fig. 63), which directs the stream continuously where desired. It is difiicult, however, to secure jjerfect adaptation of this to the calibre of the vagina or vulva. Hot Water Injections. — Dr T. A. Emmet has con- ferred an invaluable boon by introducing into practice the injection of vei'y hot water into the vagina, not for its own treatment only, but for the purpose of removing congestions in every part of the pelvis. Already this is acknowledged on all hands as a most perfect curative measure in many forms of uterine or pelvic disease, though it is seldom carried out quite efficiently. Explain it as we may, it is an undoubted fact that very copious injections of very hot water, with the pelvis well raised, do tend temporarily, and often permanently, to remove that venous congestion which is the most troublesome element and the greatest obstacle to recovery in all utero-pelvic troubles. In all chronic enlar,s-Atlantic homes. The sons of the New World will have to re-act, on a magnificent scale, the old story of imwived Eome and the Sabines." There is hardly an American physician who has specially treated the diseases of women who does not corroborate these words. Dr GaiUard Thomas {Diseases of Women, 1880, p. 44) says : — " Unfortu- nately the restless, energetic, and ambitious spirit which actuates the people of the United States, has prompted a plan of education which by its severity creates a vast disproportion between these two systems (the nervous and muscular), and its efi'ects are more especially exerted upon the female sex, in which the tendency to such loss of balance is much more marked than in the male. The results are, rapid development of brain and nervous system, precocious talent, refined and cultivated taste, and a fascinating vivacity on the one hand ; a morbid impressibility, great feebleness of muscular system, and marked tendency to disease in the generative organs on the other. But the mere existence of this fact is not the most melancholy feature of the case ; it is far more pain- ful to see mothers listening to it, admitting its truth, and yet calmly and dispassionately choosing to make the trial, as we see them doing constantly." Dr Emmet {op. cit, p. 20) says : — "I hold that it is not practicable to educate a girl by the same methods foimd best for the boy, without entailing serious consequences, for the ovaries will always be aiTested in their gi'o-n-th if the brain is forced. Even when the coiu'se of study is comparatively moderate, functional distiu-bances are of too frequent occun-ence to admit a doubt as to the cause I not only endorse Dr Clarke's views as far as he has gone, but my o\w\ experience leads me to believe that the evil is even more serious than he has represented. To enable her to reach the highest physical development, the FEMALE EDUCATION. 101 young girl in the better classes of society should pass the year before puberty, and some two years afterwards, free from all exciting influences. Her dress, diet, and habits of life should be carefully looked after as if she were a child — her mind should be occupied by a very moderate amount of study there should be no night studying under any circumstances. After the menstinial function has become permanent, normal in character, and free from pain, she can begin to increase the number of her studies, but afterwards, at the time of the molimen, she should observe the same rule of rest, mental and physical." Dr Goodell {op. cit, p. 420) says: — " From the age of eight to that of sixteen our daughters spend most of their time within the unwholesome air of the recitation room, or in poring over their books when they should be at play. As a result, the chief skill of the milliner seems to be directed towards concealing the lack of organs needful alike to beauty and to maternity, and the girl of to-day becomes the barren wife or the invalid mother of to-mori'ow. Surely a civilisation that stunts, deforms, and enfeebles, must be unsound." Such is the Cassandra-like tone of every modern American physician. Our own highest authorities, and therefore generally those who have attained a somewhat mature age, say much less on tlie topic, for obvious reasons, but the importance of the subject must justify me for inserting a quotation from a recent English writer. jMr Lawson Tait (Diseases of the Ovaries, 1883) says : — " There has grown up a desire to educate women in exactly the same way and to the same extent as men. It would be easy for me to show, were any charge of obstructiveness or want of liberality to be made against me, that throughout my public life I have ever been in the front rank of those who advocate perfect freedom of every kind of instruction for every one who may desire it ; and I have been particularly strong in the expression of m}- views that there should be restriction of neither class nor sex. But it is useless to disguise the fact that, inasmuch as women have functions to fulfil which men are free from, it is not to be expected that women can, with safety, do the work of men, and at the same time properly fulfil their own special functions as women This is no place to air political crotchets, but I own myself an advanced advocate of women's rights ; at the same time I cannot help seeing the mischief women will do to them- selves and to the race generally if they avail themselves too fully of these rights when conceded To leave only the inferior women to perpetuate the species will do more to deteriorate the Inunan race than all the individual victories at Girton will ilo to l)enefit it. This overtraining of young women is wholly unnecessary in the interests of Imman progress, and it is mischievous alike to thcuiselves and U* 102 PHYSIOLOGICAL DIFFICULTIES IX FE:\IALE EDUCATIOX. humanity Those who advocate the equal treatment of the sexes must bear in mind that great culture in a man does not unfit him for paternity, but, on the contrary T\-ill help him in the struggle for existence to maintain a family. For women, on the contrary, excep- tional cultm-e will infallibly have the tendency to remove the fittest individuals, those most likely to add to the production of children of high-class brain power, from out of the ranks of motherhood.'"'' This is hardly the place to discuss this question further, however, but I will merely endeavour to give as soimd advice as I can on the subject to the 3'oimg practitioner who may be consulted as to the education of a girl say from twelve to twenty years of age, and I may also refer him. to a lecture on the subject published by me in pamphlet form (Cornish, Manchester, 1884). If asked what he thinks of the "higher education " of woman he would be light in saying that there is no field of education tabooed to her by natm'e, that the wider, and above all the more thorough, her education is, the better woman will she become, provided ALWAYS, as the lawyers say, that the conventional period of gh'lhood is prolonged sufficiently, and that she is educated where there is sufficiently inteUigent oversight to acknowledge the fact that, during a portion of every month, rest and relaxation from, severe work or study are required. If he is told that her success or maintenance dm'ing life depends on her working -pari -po.s.su, or along with young men of the same age, it will be his duty to say that the Chinese cram system of the day is playing havoc with oui' young men, in spite of theii* cricket, football, and other antidotes, and in spite of the fact that they are not handi- capped by the household duties which fall to the lot of all our middle class girls. It will also be his duty to say that work of this kind, carried on " week in, week out," will probably, in a large number of cases, entail either the unsexing of the girl or the exaggeration of all the weak- nesses incident to her sex. In oiu' complex civilised life, dangerous occupations must be followed by some ■. the risks involved, and the remuneration held out, must not, however, be concealed. To persuade the Enghsh universities to formulate degrees, and plan coiTCsponding work for women — degrees which -^dll be fitted to acknowledge those types of culture in which women excel, and work which will allow for their physio- logical position as the futiu'e healthy mothers of oui- race, — this must be the work of women themselves. There are better materials for this purpose in England than elsewhere, and I have not the slightest doubt that the common sense of oiu- people will solve the diflicu.lties involved. Mistakes are inevitable at the commencement of all great movements. I leave those remarks on the hygiene of women, which are called for by the special conditions of child-bearing, to the obstetrician. It will, however, be well to say a few words now on two diseased conditions which, CHLOROSIS. 103 though not by any means confined to the female sex, are much more fre- quently met with in its members. I allude to the condition of ansemia or chlorosis, and to that of nervous exaltation, depression, or excitability, ^Yhich I have included under the one term " neurasthenia." Chlorosis. Chlorosis, chloro-anDemia, or, popidarly, green-sickness, is but a form of anaemia, of diathetic rather than depletive character, though it is often apparently aggravated or even commenced by losses of blood. It is not the same as pernicious anaemia, for, under proper treatment, its tendency to death is rare, and its curability is common. Its diathetic origin is rendered probable from its frequent accompaniment by nerve disorders, and by its frequent yielding to treatment adapted to disease of the nervous system, when ferruginous remedies have failed to produce effects such as are usual in ordinary anaemia. It is most common about the age of puberty, though it is by no means absolutely confined to that period ; nor is the greenish tinge which often accompanies the pallor of the affection, and which has given to it its name (;)(Xwpo9, green), confined to that time of life, or even absolutely to the female sex. I am aware that many distinguished authorities, especially of the French school, draw a much wider distinction betAveen anaemia and chlorosis than I have now done. I could not hope to define these differences, however, without an amount of logomachy, or contention about mere verbal dis- tinctions, which is foreign to the scope of our present work. The blood-changes found in chlorosis are — diminution in the total quantity of blood, deficiency in both red and white corpuscles, and diminution in the total as well as relative amount of hasmoglobin, to a greater degree than in ordinary anaemia. Deficiency in the albuminous constituents is not so marked or so frequent as in ordinary anaemia, and the fatty and saline constituents are also foxind in almost normal propor- tion. The fat of the body is sometimes considerably diminished, but very often, and these are the most troiiblesomc cases, it is in excess. Anatomical changes in the tissues, especially the lieart and aorta, may be slight, or may 1)C as considerable, as in the worst forms of anaMiiia. Virchow held that the essential pathological condition was a hy]Kii)lasia of the heart and great vessels, — a theory manifestly inconsistent with the ra])id recovery often observed. For these anatomical or pathological details the student may considt the ai'ticles on "Anaemia," "Chlorosis," and " Blood Changes " in Quain's Dictionary of Medicine, or Bcciuercl's Maladies de V Uterus, vol. ii. Synijnoms. — The affection usually comes on insidiously, but is some- times very sudden in its onset. The most striking symptoms are the 104 CHLOEOSIS, ITS CAUSATION change in colour and complexion, and the pallid mncous membranes ; but these are speedily accompanied by breathlessness, palpitation, dyspepsia, and great debility, and sometimes by serous effusion into the cellular tissue. This last symptom, and even optic neuritis, may occur without any albuminuria ; the urine is generally abundant, pale, and of low specific gravity. A certain amount of cardiac hypertrophy is often present, and loud spaneemic murmurs are rarely absent. The whole of the symptoms bear a striking resemblance to many of those met Avith in Bright's disease, many organic cardiac affections, gastric ulcer, and chronic tubercular peritonitis ; and before we can be certain of our diagnosis, these must in every case be eliminated by the' most careful inquiry and inves- tigation. Menstrual disorder in some shape is rarely if ever absent, but it may take the form of total suppression, of diminution and irregularity, or of passive monorrhagia or nervous dymenorrhoea (see Chap. VII.). Leucorrhoea is an almost constant concomitant. It is surprising how difficult it often is to ascertain whether these conditions were antecedent to the chlorosis, and possibly causative, or succeeded to it, and were therefore possibly its effects. This chlorotic condition may continue unaltered through a comparatively long life, or it may yield to suitable treatment. There is a constant tendency to return, how^ever, which diminishes as full maturity is reached. Neuralgia and neurasthenia, or nerve weakness, in every form, including hysteria, are frequent accom- paniments of chlorosis, and yield to the same treatment ; but it cannot be denied that they may severally exist quite independently of one another. Causation. — Our present knowledge of the patholog}'^ of chlorosis or of ordinary ansemia is so imperfect that it must render us cautious in dogmatically assigning their efiicient causes. The age of commencing, or only partially-established, puberty, is undoubtedly a common, though not a necessary predisposing element. The affection is very frequently hereditary, and is said to occur most frequently in towns, but one often encounters well-marked cases among country girls. In many instances we have no other known causes to guide us in treatment. There is sufficient evidence to show that whatever tends to deprave the nutrition of the body, in the way of deficient food, exercise, air, and light, or what- ever tends to lower the nervous tone, in the way of mental anxiety, loss of rest, over-exertion, — especially mental, abnormal sexual excitement, or the various troiibles which the adolescent girl experiences at home, at school, or in society, may cause or promote the tendency to this affec- tion. Their removal will at any rate materially aid in its cure, and their continuous existence Avill generally be found incompatible with this. Treatment. — The treatment of chlorosis sho\ild, in the first instance, be attempted by prescribing the ordinary remedies for ansemia, espe- AND TREATMENT. 105 cially iron in its most assimilable forms, combined with attention to even- hygienic error which can be ascertained and con-ectcd, under the social conditions of the patient. In a certain number of cases a rapid cure is attainable by this means alone. We know not positively why arsenic oi- the salts of manganese succeed in many cases where iron fails, but this is so often the case in chlorosis, and the patients have so often tried the ferru- ginous treatment in vain before I am consulted, that I have got into the habit of prescribing one or both of these drugs from the first, in almost every case ; and the rapid improvement Avliich has often followed has, I be- lieve, brought to me more kudos than any medication of a less empirical or more scientific character which I have pursued. The arsenic may either be prescribed as Fowler's solution, 3, gradually increased to 5 or 6, drops, in water, after a meal ; or as arsenite of iron, gr. -^ to gr. ^, throe times daily. The manganese should be given separately as the prepared black oxide, 10 to 20 grains in honey or syrup. The connection of chlorosis with diseases of the uterus must be carefully weighed. In tlie great majority of cases, local disease, such as catarrh of the uterus or vagina, or disordered menstiiiation, is the result, not the cause of the chlorotic state ; but a vicious circle of causation may ensue, the catarrhal discharge, or over-abundant mensti-uation, becoming in its turn a source of weakness or impoverished blood. Moreover, when chlorosis occurs during married life, long subsequent to the full establishment of pubert}-, the haemorrhages or discharges, or perhaps even the nervous irritations caused > by chronic endometritis, or ovarian diseases, niptured cervix, oi- even ruptured jDerineum, may be the primary causes of the chlorosis, and their remedy, secundum artem, may prove the only efl&cient means of its cure. To the nature and treatment of such diseased conditions the remainder of this work will be mainly devoted. The form of acute chlorosis which occasionally folloAvs the puerperal state is sometimes in- dependent of severe losses of blood ; and unless there are strong evidences of chronic metritis, or even when those are present, it nuist be considered as allied to, and demanding the same general treatment as the ordi- nary form which is met with during the first estal)lishment of men- struation. The sun treatment of disease, that is, constant exposure in a semi-nude condition to the rays of tlie sun (Heliothorapy), oarricd on at Weldes and some other parts of southern Europe, has been found l)onetioial in some otherwise intractal)lc cases. In many instances a tolerably rajjid cure of the condition is obtainable by a modification of AVeir Mitchell's treatment. That is to say, the treatment, which 1 shall mention more fully by and by, may be employed, with tlie omission t»f the isolation and removal from home of tlie patient, wliicli add so mucli to its diffi- culty and expense, but whicli are indispeiisalilo wlicn it is carried out for the cure of more strictly nervous affections. 106 NEURASTHEXIA. Neurasthenia. I use this term here to express, as far as possible in one word, a very great variety of nervous phenomena which are certainly not confined to the female sex, but which are met with in that sex much more fre- quently and with more prominence than in the other. The condition is closely allied to, and in very many instances quite indistinguishable from that other vast group of symptoms which is usually designated by the term hysteria. Indeed, it is very doubtful whether even the typical paroxysm of hysteria, the globus hystericus, &c., are not mere manifesta- tions of neurasthenia. Nor is the more chronic and continuous state of matters described as neurasthenia to be placed altogether in opposition to the more fitful and evanescent state of hysteria, for in each we may have cases of great evanescence of symptoms, and in each a more or less continuous state of nervous affection. The condition known as hystero- epilepsy, of which the student will find a most excellent description by Dr Mills in the American Journal of Medirxd Science, October, 1881, comes within the same category, and perhaps also some cases of epilepsy. At any rate, the remarks as to the treatment of one will apply equally to all, except in such cases as can be traced to a definite organic basis or anatomical lesion. The remarkable uniformity of symptoms observed by Charcot in hystero-epilepsy has hardly been met with in England, and I think is not likely to be until some experimenter can establish a vast clinique where full play can be given to the mimetic tendencies, or liability to be influenced by imitation, or association, or suggestions of ideas or actions, which is prevalent in all neurasthenic or hysterical patients. Symptoms. — A state of great general debility is common to nearly all cases of neurasthenia, but this may show itself much more prominently in one or another direction. Inability for physical exertion of any kind, constant tiredness, may or may not be accompanied by inability for mental exertion, or what is very common, there may be paroxysmal exacerbations of the one form of exhaustion or the other, or certain sets of muscles, or certain kinds of brain work may be peculiarly affected. The loss of power of taking walking-exercise is the most common and early symptom, and local cramp, or utter general exhaustion, foUow on attempts to enforce its practice. Feebleness of circulation is shown by cold extremities and cardiac disturbance. Sleeplessness is a common and distressing symptom. Morbid sensations, such as neuralgia of every kind, spinal tenderness at certain points, formication more rarely, and the like hypersesthesise, are seldom absent. The patient becomes in- tensely hjqDOchondriacal, exaggerates every symptom, and on the slightest ITS FORMS AND CArSATIOX. 107 suggestion can be made to experience, imagine, or invent — it is often hard to say which — other sj'mptoms. The want of exercise leads to dyspepsia, constipation, and simihxr disorders. Then follow in rapid train, in typical cases, the dreary round of hj^sterical inventions of any or evexy imaginable form of paralysis or spasm, tetany and epileptiform attacks included. Loss of appetite is usual, and may be carried to the extent of voluntary starvation. All the common symptoms of uterine or ovarian disease may be copied in perfection, or may be merely the exaggeration of a slight actual basis of fact. Emaciation, to an extreme extent generally, follows as a natural consequence, or if the patient retains a certain amount of fat it is accompanied by chlorosis or antemia. The emotional conditions commonly called hysterical may be present, or the patient may be simply sluggish, or, what is perhaps worst of all, most amiably and even religiously submissive to the aches and pains, or paralyses and spasms, she is called on to endure. Slight degrees of this neurasthenic condition are very common in the female sex, but with a resolute will, the absence of injudicious pampering, and a little kindly but firm medical advice, they speedily pass away. The same remark applies to over-worked or self-indulgent males. A distinguishing feature in all these cases is that there is never any real loss of mobility or sensation — all the reflex phenomena of health, the " myotatic " contractions of Gowers, are easily elicited, and there is no change in the normal electric reactions. Recovery even in slight cases is usually slow, and relapses ai-e common. It is hardly necessary to speculate here as to the essential pathology of these cases, but everything seems to point to what we, in our ignorance, must term functional disease of the spinal and other nerve centres, as a leading factor. Ansemia of the brain or cord, with perhaps occasional hj^ersemic ebbs and flows, must doubtless produce changes in their nutrition too minute for the anatomist to recognise, and to these we must look for an explanation of most of the leading symptoms. Causation. — The period of puberty or adolescence is by far the most common time for the development of these sj'^mptoms, and one comes therefore to the conclusion that the mental and bodily changes then going on, are at any rate predisposing agents. Not a few cases, how- ever, are met with in middle age, or at the climacteric i^eriod, while in old age they are exceedingly rare. Another strong predisposing element, one which I have seldom seen entirch' absent, is the existence of a heredi- tary neurotic constitution, as evidenced l)y the occurrence of neuroses in other members of the family. A more immediately exciting causation is found in over-exertion, or prolonged emotion, or in circiunstanccs violently affecting the passions. Although minor degrees of neuras- thenia may have previoiisly existed, the occurrence of the more striking 108 NEUEASTHEXIA. phenomena is almost always preceded by one of those causes. Physical over-fatigaie is comparatively seldom the cause in the female sex unless combined with anxiety or care, as in long-continued nursing. Mental over-exertion, especially if experienced during the menstrual periods, is, on the other hand, a too common factor. That sexual excitement, whether suppressed or unduly fostered, is occasionally a cause is absolutely certain. The reticence of the sex on such subjects renders it impossible to say how often this is the case. That the nervous and vascular general and local changes accompanying ovulation and menstruation are often strongly causative may be safely assumed, but I would earnestly caution the young practitioner against assuming too freely that there is always a corresponding or accompanying erotic tendency. Mal-nutrition, in nearly every case, plays a part in the causation sooner or later, whether it is due to insufficiency, or improper character, or faults- digestion of the food ; and almost any departure from strict hygienic laws tends in the same direction. There is nothing which produces such baneful effects in this affection, whether as a primary cause or a fertile aggravation of the symptoms, as the injudicious sympathy of friends or relations, or even medical advisers. Let a young girl, or a young man either, fall into the hands of a fond mother or other relative, who makes it the biisiness of her life to minister to every little want, to magnify every little ache or pain, or to call them into existence by her inquiries and suggestions, and the patient may safely be pronounced a hopeless invahd till he or she is rescued from such unfortunate sim-oundings. One cannot cure these ministering angels, as the patient is apt to consider them, of their mischievous, though well meant practices. The most important question with regard to causation remains for consideration. How far is uterine, or ovarian, or pelvic disease to be considered as a predominant cause of this neurasthenic state ? Few- cases continue long without some manifestations of apj)arent uterine dis- ease, and there are not many in which, after a time at any rate, physical signs of uterine versions or flexions, of chronic metritis or vaginal catarrh, or of other gynic disorders, are not encountered. By the time the patient has run the gauntlet of several physicians, and has reached the gyn£ecologist, this is almost sure to be the case, and the attention of her friends and herself will probably have become riveted upon these symptoms. Now, that real uterine or pelvic disease may be the starting- point, I have no manner of doubt. Its symptoms and signs may have been present long before there were other symptoms of general neuras- thenia, the continued reflex irritation of the spinal and sympathetic nervous system, and the impoverishment of blood thus brought aboxit may be the main etiological factor, and the cure of the local affection may produce a speedy improvement, easily followed i;p to complete NEURASTHENIA. 109 recovery by simple hj'ji'ieuic means. All this lann l)c, and occasionally is, the case. It is the duty of the shrewd physician to put together the history of the various symptoms without bias, and to make sure that he can speedily alleviate the local malady, before he attempts to treat the case from this direction. But for the most part, and especially in the instance of young or unmarried women, the relations of cause and effect are precisely the reverse. It is the anemic or neurasthenic condition which gives rise to local pelvic congestions, to cataiThal discharges from uterus or vagina, to consequent displacements of the uterus even, and to the multiplicity of ovarian, uterine, or pelvic aches and pains. I cannot better illustrate this than by a quotation from Dr Goodell {op. dt., p. 398). "Take, for instance, this too common picture from life. A girl Avho entered puberty in blooming health, and without an ache, is over-tasked and over-taxed at school, and her health begins to fail. She loses her appetite and grows pale and weak. She has cold feet, blue finger nails, and complains of an infra-mammary pain. Headache, and back-ache, and spine-ache, and an oppressive sense of exhaustion distress her. Her catamenia, hitherto without suffering, now begin to annoy her more and more, until they become extremely painful, and at these times dark circles appear under her eyes. Her linen is stained by an exhaiisting leucorrhoea, and bladder troubles soon set in. She is wearied beyond measure by the slightest mental or physical exertion ; a grasshopper is a burden to her, and she finally becomes hysterical. Now, very unfor- tunately, the idea attached to this group of symptoms is that the repro- ductive organs are at fault, and that the unit of resistance lies in the Avomb. A moral rapj is therefore committed by a digital or a speculum examination, and two lesions will be found. Firstly, as a matter of course, a vaginal anteflexion, and, secondly, an endometritis. These are at once seized upon as the prime factors, and she is accordingly sub- jected to a painful, an unnerving, and a humiliating local treatment. Unimproved, she drags herself from one consulting room to another, until finally, in despair, she settles down to a sof;x in a darkened room, and lapses into hopeless invalidism." I wish I could continue the quotation, but what I have already given should be engraven on the memory of the young practitioner before he enters further on the study of the local disorders of women. Not a few of the cases in which it is the fashion now-a-days to excise the ovaries are of this class, and might be cured, at any rate in their earlier stages, by hygienic means. Diagnosis. — Neurasthenia, in ordinary cases, is easily recognised by the symptoms given above, and especially by the fact tliat the nmnerous subjective phenomena are found, on careful examination, to lie unaccom- panied by ol)jective signs. It is chiefly with tubes, or myelitis, or \ \ \ 110 TREATMENT OF NEUEASTHENIA, sclerosis of the cord, or other organic spinal or cerebral affections that it may be confounded, Avhen pseudo-paralytic, or spasmodic, or conviilsive phenomena become developed in its course. I have known very clear- headed physicians deceived in this way, and if I have rarely, though not without exception, been so myself, in the case of females, it is due solely to the fact that where doubt existed, I have ever placed reliance on the age, sex, and surroundings of the patient, on the occurrence of uterine phenomena, and on the other points which have rendered the diagnosis of neurasthenia probable, even when they conflicted with much of the evidence derivable from modern methods of investigating nervous and muscular lesions. Treatment. — The treatment of neurasthenia mainly consists in remov- ing its causes when they can be ascertained. Rest is an important element in all cases, rest from brain work, from wearing anxieties, and from physical exercises beyond the strength of the patient. It is, how- ever, occasionally a most difficult task to determine when a certain amount of enforced exercise is likely to be more serviceable than ab- solute rest. I cannot on this point do better than quote from Dr Weir Mitchell {Fat and Blood, Lippincott & Co., 1884, third edition) : — " Sometimes the question is easy to settle. If you find a woman who is in good state as to colour and flesh, and who is always able to do what it pleases her to do, and who is tired by what does not please her, that is a woman to order out of bed and to control with a firm and steady will. That is a woman who is to be made to walk, with no regard to her aches, and to be made to persist until exertion ceases to give rise to the mimicry of fatigue There are still other cases in which the same mischievous tendencies to repose, to endless tire, to hysterical symptoms, and to emotional displays, have grown out of defects of nutrition so distinct that no man ought to think for these of mere exertion as a sole means of cure. The time comes for that, but it should not come until entire rest has been used, with other means, to fit them for making use of their muscles But between these two classes lies the larger number of such cases, giving us every kind of real and imagined symptoms, and dreadfully well fitted to puzzle the most competent physician. As a rule, no harm is done by rest, even in such people as give no doubts about whether it is or is not well for them to exert themselves I do not think it easy to make a mis- take in this matter unless the woman takes with morbid delight to the system of enforced rest, and unless the doctor is a person of feeble will, and the man who resolves to send a nei'vous woman to bed must be quite sure that she will obey him when the time comes for her to get up again." The degree of mental work permissible must be decided in each case on almost priecisely similar principles. Of course WEIE MITCHELLS SYSTEM. HI the period of rest must bo utilised to the fullest extent in improvino- the nutrition of the patent. The utmost attention must be paid to securing a plentiful supply of wholesome food, such as the stomach will digest, and iron, arsenic, or manganese have here their fitting place. The moderate and judicious use of hydrotherapy suits some cases remarkably well, but early hours, plentiful and regular meals, and very mild amusement, form a part of this treatment. I have already said enough as to the place which special uterine medication occupies in the treatment of these cases. In very many, separation from unwholesome influences and sur- roundings, with the hygienic regimen which will suggest itself to every physician who understands the true nature of the case, will suffice for a cure, if sufficiently prolonged. But in aggravated cases, nothing has been suggested of more value than the combination of several indications in one routine system proposed b}^ Dr "Weir Mitchell. It is almost impossible, in the few sentences at my command, to convey the full drift of this combination, in one systematic course of treatment, of these separate remedial factors — absolute mental and bodily rest, systematic and successful rapid nutrition of the tissues, utilisation of the large quantities of food given for nutritive purposes, and prevention of its otherwise deleterious consequences, by systematic rubbing and electricity, together with perfect seclusion of the i^atient from all influences but those of her medical adviser and trained attendants. Every practitioner who has an extreme case in charge should carefully study Dr Mitchell's book for himself, and decide how far the circiim- stances of the patient permit of the adoption of its recommendations. The absolute rest is necessary for a time, varying in different indi- viduals, to reduce the frequeney of cardiac action, to calm the nervous system, and avoid all tissue changes in excess of what are absolutely required. The feeding is conducted mainly by administering gradually increased quantities of skimmed milk, with the addition, from time to time, of other articles of diet, until enormous quantities of food are con- sumed with avidity. The patient gains fat and blood, and increases in weight, in an incredibly short space of time, while the accumulation of waste products in the system, and injury to digestion, are prevented by daily massac/e, or scientific kneading of the whole surface, and to some extent by the application of the Faradic ciirrent to the muscles. The necessary seclusion can only be secured by removal to an establishment where every detail ordered will be rigorously enforced. I could add several to the list of apparcntl}' almost miraculous cures, related by Mitchell and others, of seemingly lK)})clessly paralytic invalids, or of those 112 DIFFICULTIES IX THE WAY OF in whom muscular, and nervous, and mental power were at the lowest possible ebb.^ There are, however, several drawbacks which have to be somehow overcome, or they will prove prohibitive of the whole system of treat- ment to large nimibers of suitable cases. Having so strongly recom- mended a perusal of Dr Mitchell's original work, I think it is more pro- fitable to mention these drawbacks than to dilate further on its details. The expense necessarily entailed by separate board and lodging, with skilled attendance, and massage, and proper medical siipervision, is great, and the six or seven weeks which are necessary, to set the patient fairly on her legs again involve an outlay of from £40 to £60 at least. It is doubtless well spent money for those who have got it, and true economy in the long run. Fortunately these cases are much less conmion in a severe form among the poor, a proof of how predominating is the influence of mental over physical causation, and of the deleterious influence of luxurious coddling and pampering. But they do occur, and occasionally bring ruin to a poor and worthy family, every farthing beyond what is imperatively required otherwise going to comfort the helpless and exacting member. It would be an interesting fact to determine how many chronic invalids are found in our workhouses who might have been saved by a few weeks' proper treatment, or who might yet be saved, and what would be the comparative cost to the community of curing or permanently housing them. Another great difficulty lies in olitaining the consent of the friends or of the patient to the necessary separation. A little tact will almost always persuade the latter, but the former can hardly be made to see that their fond care and attention are the most deleterious influences surrounding the case. They fight for modifications of the seclusion, which would render it totally ineffec- tual, and only the gradual increase in the symptoms at last overcomes their scruples. Time and familiarity with effective cures thus brought about will tend to diminish this difficulty. Another difficulty, not an imao-inary one, lies in the fact that the treatment is almost necessarily removed from the hands of the ordinary practitioner to a stranger. The patient and her friends feel this, if they have confidence in a long-tried friend and adviser, and it is only human nature to suppose that he may occasionally resent it himself. Yet in many cases the patient has ^ot beyond his power of efficient control, by too long sympathetic associ- ation, and a change is absolutely required. It is hardly the fault of the doctor, for in many instances a mere exchange of advisers between two cases would do all that was necessary. This obstacle will be difficult to overcome in the country, but I have found no difficulty in arranging for 1 Dr Playfair of London and Di* Little of Benrhydding were among the' first to adopt this treatment fully in England. WEIK MITCHELLS TREATMENT. 113 the necessary treatment in Manchester, at Mrs Allsop's excellent nursing home, under my own supervision, or that of any other practitioner, and l)robably most large cities will afford similar opportunities. Before undertaking the systematic treatment of such a case, previously under his own care, the practitioner should, however, feel very sure indeed that he holds the reins firmly, and that the steed has never got the bit between her teeth, as far as his driving is concerned. If he is in en-or here, a lamentable failure will result, and the plan of treat- ment, and the practitioner himself, will be greatly discredited. One thing is absolutely necessary, if medical men are to be expected, at their own temporary loss, and with much risk of offending and alienating the fi-iends of the patient, to urge this system of treatment in suitable cases, there must be no quackery at the establishments selected. The patient goes there on the advice and responsibility of her own medical adviser, who deserves therefore the credit of success, or at any rate should fairly divide it with the temporary executor. I am sorry to say that this has not always been the case, and that I have known very great self-exaltation claimed, and widely admitted, in favom- of the directing phj'sician, and at the expense of the physician to whose skill in diagnosis, thorough appreciation of the treatment, and unselfish zeal in insisting on its adoption, the patient owed her delivery from social death. My colleagTie, Dr Ross, has two admirable chapters on cerebral and spinal neurasthenia, as observed chiefly in the male subject (Diseases of the Nervous System). At first glance there would appear to exist a much greater difTerence between the sj-mptoms observed in the male and the female, than is evident on further study. Paresis is more common in the female, numbness and pain in the male. The change of life is perhaps the more common factor in the male, and puberty in the female, bvit with many exceptions. In the middle aged man we are not so apt to attribute his varied repertorium of symptoms to fanc}-, caprice, or even untruthfulness, as in the hysterical girl — a fact which should make us more lenient in our judgment of the latter. On the other hand, we have just sufl&cient cases, in the young adolescent male, of utter temporary abandonment to the highest degrees of distorted will and moral nature, of false paralysis, and of con\iilsive tetany, to show us the intrinsic similarity of the affection in both sexes, modified liy the special surroundings of each. Dr Ross and I have recently treated together a most remarkable case of the kind in a young man, and we both, I think, were much impressed with the idea that it is a fortunate circumstance, as fiir as treatment is concenied, that these cases of great neurasthenia in the young do occur so much less frequently in the male. I am pleased to note that so competent an authority attaches an im- ])ortance to the "Weir Mitchell treatment, precisely coiTcsponding to Avliat I have above cx])ressed. ii 114 DISEASES OF THE VAGINA. CHAPTER V. Diseases of the Vagina. — -Vaginitis, Acute and Clironic. Leucorrhoea. Tumours and Growths, Foreign Bodies. Wounds, Ulceration, and Mstulte. Occlusion. Prolapse. After the digression of the two preceding chapters, the diseases of the vagina follow next in natural order to those of the vulva. In many instances their pathological characters and their treatment are so similar as to require little more than recapitulation, and in not a few cases the maladies of the one region are sim|)le extensions by contiguity from the other. In acute inflammatory affections of the vagina the introduc- tion of the speculum can hardly be borne, and certainly the smallest sized tubular instrument is often the best for ascertaining the general state of the walls and their secretions ; but Avhen small areas of dis- ease, such as fistulse, have to be searched for, and still more when they have to be operated upon, the duck- bill becomes indispensable, and such an instrument as that of Scanzoni (fig. 16) may be of service. A duck-bill speculum with a long, wide fenestra in its blade is also serviceable for examining or operating on small fistulse or ex- crescences of the posterior vaginal wall. There are two ways of describing the vagina. According to the one, it is a musculo-mem- branous tube, more or less cylindrical in form, though compressed, and extending from the vulva obliquely through the pelvis, till it embraces the cervix uteri. This idea is ty^Dically showai in Houston's well-known and often-copied diagram (fig. 69), and in the more recent and carefully-executed drawings of Sappcy. According to the other, " the vagina is a mere slit in the pelvic floor, although it is often erroneously described as a tube or cavity." This is shown in Hart's Fig 69. —The Pelvic Viscera in Profile (Houston). IS THE VAGINA A TUBE OK AN INTEitSrACE ? 115 druwiug (fig. 70), aud it is, anatomically speaking, tlic more correct esti- mate of what we find in the healthy virgin female. It is very desirable that the student of gyneecology should not fail to realise this fact. At the same time the vagina is, embryologically, a part of the genital tube or canal, and, in its physiological aspects, in copulation, parturition, and even menstruation, it plays the part of a tube ; and in describing its ailments or their treatment, it is almost impossible to use language which does Fig. 70. — Vertical Section of the Vagina Fxc;. 71. —Section of Pelvis (Hart), u., urethra; ■;;., vagina; (Rannej'-Foster). a.l., anterior lip of cervix; p.l., posterior lip ; o.u., os uteri exter- num ; -p-i perineal body. not fall in with this conception. S^^ecula, even the duck-bill, dilators, and many other instruments, are all made and used with this conception in view ; and I see no harm in it, if one does not forget the one form of truth, while acting upon the other. lianney's diagram (fig. 71), modified from Foster, shows very clearly the true relation of the canal to sur- rounding parts. Acute Vaginitis, Acute inflammation of the vagina — vaginitis, colpitis, or elythritis — is, like acute vulvitis, very frequently the result of gonorrhoea, but it may also arise from other causes, and there is the same difficulty in differen- tiating between the specific and non-specific forms. The suddenness of the attack, its acuteness, the urethral and vulvar involvement, the labial oedema, are all characteristic of the gonorrhceal form, but they arc never absolutely conclusive. True gonon-hcual vaginitis may afi'ect only the 116 ACUTE VAGINITIS. lower part of the vagina, but there are cases also where it affects only the npper part. Even the occurrence of apparently gonorrhoea! infection of the male is not certain proof of gonorrhoea in the female, for purulent discharges of a non-specific character in the female may produce in the male an affection hardly to be distinguished from gonorrhoea, except perhaps by its milder character and amenability to treatment. Cmises. — Any traumatic injury, surgical operations, too strong injec- tions, or medicated pessaries ; irritating uterine discharges, diabetic uxine ; cold, especially during a menstrual period, or after delivery or miscar- riage ; the exanthematous fevers ; badly-fitting uterine supports, or their too prolonged retention, have each occasionally figured as exciting causes of acute non-specific vaginitis. The symptoms are those of mucous inflammations generally — heavy, dull, aching pain, or smarting — with tenesmus, " bearing down," spasm of the sphincters of the vulva, anus, or bladder, frequently accompanied, at the outset, by sharp fever, the parts being acutely painful to touch. The mucous membrane is at first red and velvety, perhaps bleeding easily on touch ; the secretion is primarily diminished, bu.t soon becomes increased, the whole affected surface being covered with pus or muco-pus. This secretion is acid, and sometimes very offensive. The squamous epithe- lium is shed in large quantities and washed away with the discharge, so that ra\^mess occurs, and adhesions may take place between opposite surfaces, or between the cervix uteri and vaginal w^all. In old people these attacks, by their frequent subacute occurrence, tend to cause con- traction of the vagina. The acute form may end in resolution in a few days, or a week or two, or it may subside into the chronic fonn, giving rise to endless trouble. There is the same danger as in vulvitis of extension to the bladder, to the inguinal glands in the form of bubo, or to the uterus, Fallopian tubes, or ovaries. Such extensions may give rise to inflammation of these organs, with subsequent abscess or strictures, and consequent sterility, peritonitis, or death. This last result, fortunately rare, may occur from the extension of very subacute or even chronic forms. We have also, in vaginitis, a granular form of the disease, due to the affection mainly of the small vaginal papillae ; indeed, some measure of this is usually seen at the commencement, and, much more rarely, there occur minute pustules, as if the affection involved a glandular rather than a papillary element. Gangrenous cases are also reported, where the vaginal sheath, including the muscular tissue, has come awa}' as a sloughing cast, recovei-y depending on how far the parts below are affected. These casts must not be mistaken for mere epithelial exfolia- tions, which, in a more or less complete form, are frequently thrown off" when there is but little local inflammation or constitutional disturbance. TREATMENT OF VAGINITIS. 117 True diphtheria, of zymotic origin, is sometimes met with, as on the vulva ; and Schroeder, and others, describe a croupous contlitiou dependent on local in'itants, such as urinary fistulee. What I have seen under tliesc circumstances Avas a mixture of epithelium, pus, and urinary salts. Matthews Duncan mentions a rare form of vaginitis, v. emphyseviatoga, where the surface of the vagina is covered with minute air vesicles ; other writers have described them as present in the cellular tissue beneath, but one would in that case expect more extensive spreading of the emphysema. In children, there is the same necessity for remembering the danger of false accusations as in the case of vidvitis, but vaginitis is rare in children, while \ailvitis is common, and in the adult, vulvitis, apart from vaginitis, is comparatively rare. The treatment, when the affection is in its acute stage, should be by complete rest, combined with cooling aperients, antiphlogistic regimen, and avoidance of stimulants. The best local application at first is the injection of warm water, either medicated with laudanum and borax, or acetate of lead, or used alone. The Avater should be as warm as it can be quite agreeably borne. But there is a certain amount of danger in all injections during vaginitis, owing to the possibilit}- of tlicir washing the secretions into the uterus, and for this reason they should be gi^^en slowly, and it should be seen that there is free exit at the vulva. A rectal suppository of morph. acet. (gr. \ ad. 5) and cxt. belladon. (gr. ii.). night and morning, gives great relief. Varioiis demulcents, — slippery elm, marsh-mallow, &c., may be substituted for the above watery injec- tions. As the more acute stage subsides, more stimulating applications become desirable, such as boracic acid, salicylic acid (R acid, salicylic. 3SS., sod. bicax'b 3iii., aqua 5iv., after effervescence ceases, filter, and add a pint of water), or carbolic acid (1 in 60, to 1 in 20). Nitrate of silver (gr. XV. ad. §1.) is not infrequently applied to the surface with a brush, through the speculum, but my experience of it at this stage is unfavour- able. A further stage of stibsidence being reached, the numerous class of astringents comes into use, and these must be relied on more and more as the disease tends to the chronic form. Alum is the most popular of these (oi.-5ii. ad. Oi.), but it is apt to cause very disagreeable curd- ling of the secretions. The boracic and salicylic acid injections arc still useful, and sulphate of copper (gr. xx.), acetate of lead (3i.), acetate of zinc (gr. xx.), sulpho-carbolate of zinc (gr. xxx.), and sulphate of zinc (gr. xxx. to the pint), are all of value in turn, for they nnist be frc(piently changed, rather than increased too nuich in strength. The list <>f astringent or antiseptic substances wliich it lias occurred to various authorities to use is of indefinite length. Sims's vaginal glass dilator (fig. 3.5) has been recommended to be worn, in oi-der to keep asunder the 118 CHEOXIC TAGIXITIS. inflamed siu-faces. I have found it badly borne in cases -svliere it was most required, and woidd reserve it for the most ckronic forms, when there is danger of adhesions. Ermnet's plan of filling the vagina with hot water, while the hips are raised, though invaluable, as we have seen, in certain uterine and pelvic affections, is dangerous in vaginitis, its object being to thi-ow the fluid backwards, and fully dis- tend the vagina, which might favour extension of the disease. "\Mien all febrile symptoms have abated, Edis's plan of injecting through a sj)eculum the giycerole of carbolic acid, 1 in 4, or P. B. strengih, often produces a very good effect, especially in the j^ersisteut granular foiin. It requires a little care, and should be retained for a few hoLU's by a tam- pon soaked in oil, and then gently spinged away. Otherwise, I do not like the use of medicated jjlugs for vaginitis. They are apt to be imtating and offensive. The internal remedies — copaiba, cubebs, and sandal wood oil — are just as effective or ineffective in the non-specific as in the specific forms. In the more chi'onic cases the patience of jDhysician and patient is sorely tried, but the frequent change of these astringent and other local remedies must be continued. I will only add to the number the solution of j)ermanganate of potash (gT. |-, and upwards, to the ounce), and a soothing mistm-e of bismuth in glycerine (gr. xx.-sxx. ad. i.), to be apphed with a biaish. Acute vaginitis has been considered, so far, mainly as a local affec- tion; but undoubtedly many cases, though less freqiiently than with the chronic form, depend entirely on constitutional states which demand our first attention. Among these we may reckon the cases occurring diiring the exanthematous fevers, or in the depressed constitutional state due to chronic alcoholism, struma, tuberculosis, diabetes, tfec. Xo local treat- ment avails mxich while these conditions are unchanged, and their com- plete or partial removal often acts as a charm on the local affection. Chronic Vaginitis (Vaginal Catarrh, or Vaginal Leucorrhcea) . Chronic vaginitis, as a mere stage of the acute form, need not further detain us. But it is, for practical purposes, advisable to speak of that condition of chronic purulent or muco-purulent discharge which is often a sequel of acute vaginitis, but more often commences with little or no febrile disturbance, and creeps on imperceptibly. Clinically we can make no distinction l)ctween chronic vaginitis, vaginal catun-h, and vaginal leucorrhooa. The causes, as witli all other catarrhal affections, arc innumerable. Constitutionally, we have damp, or hot, or very cold climates, anaemia, VAGINAL LEUCORRHCEA. 119 struma, gout, chronic alcoholism, mental or bodily over-work, and the thousand-and-one other causes which depress the vital powers. Locally, we have want of cleanliness, local irritation from frequent coitus, abuse of pessaries, tampons, or other local applications, extensions from the uterus or vulva, uterine displacements, and pelvic diseases. In fact, everything that debilitates the system, or irritates the vagina, or con- gests the pelvis, may show itself by the presence of vaginal leucorrhoea. It may last for weeks, or months, or a life-time,- with occasional exacer- bations or remissions, but that which follows as a sequel to gonorrhoea is especially intractable. In 1873, Dr Noeggerath published a remarkable paper,! in Avhich he showed, to his own satisfaction, that it was hardly possible for a woman in New York to escape infection from gleet after marriage, and that it was almost equally certain that, once infected, she must sooner or later become the subject of incurable chronic uterine, ovarian, or pelvic disease. At the annual meeting of the British Medical Association in 1876, I read a short paper,- in w^hich I endeavoured to disprove the existence of this very alarming state of matters as regards the community here; but the baneful effects of chronic gleet in the male, transmitted to the female after marriage, are nevertheless serious and frequent enough. Symptoms. — Every patient who suffers from vaginal catarrh or leucor- rhoea suffers sooner or later from back-ache, pelvic discomforts, and symptoms of anaemia or general weakness; but these symptoms, even when combined with the characteristic flow, can never be considered as pathognomonic of this affection alone. They may for a time be relied on in the young, but if not speedily subdued, should lead to local examina- tion. I have elsewhere (p. 33) mentioned the characters which differen- tiate uterine from vaginal leucorrhoeal discharges. The purulent secretion in vaginal catarrh is mixed in various pro- portions with the vaginal mucus and tesselated epithelium, and is nearly always acid, the action of the acid \\\)Qi\\ the spermatozoa being a not infrequent cause of sterility. This partly accounts for the well-known infecundity of prostitutes, although that is also partly due to more serious changes in the ovaries and Fallopian tubes, the result of gonor- rhoeal extension. Treatment. — I have already iiiib'catcd fully eiidugli the means of local treatment b}' astringent or antiseptic aj)])lications. Jjut the remedy of constitutional causes at work must, in tlic chronic form, chiefly demand attention, and in man}' instances, in very young girls, ft)r instance, to the total exclusion of local measures. 1 shoidd ntjt, however, omit tt) mention t])at alkaline injections may be occasionally sul)stitutcd for astringents ^ Die, Latentc Gonorrlwi im JFciblichen GesrhlechL Bonn. •- Brit. Med. Jour., 1S77, vol. i. p. 259. 120 CANCER OF THE YACrlXA. with great advantage, either as weak solutions of the alkaline carbonates. or as mineral waters used at their place of origin. The over-grown or over-worked yonng school-girl is as much a victim to chi'onic vaginal leucorrhoea as the too-frequently parturient woman, and there is often a vicious circle of causation. Ansemia, or debility in some form, causes leucorrhoea, and leucoiThoea adds to anaemia or de- bility, and there can be little doubt as to which end of the chain should be cut. Local apjjlications must give place, until it is found impossible to do without them, to iron, strychnia, cod-liver oil, phosphates, and atten- tion to the action of the bowels and skin. But even these will do little, without good, plain, nourishing food at regular hoiu's, early retirement to bed, out-door exercise, avoidance of mental or physical stimulants, and carefully-considered changes of climate for those who can afford them. It should be remembered by every mother, that, in the case of her grow- ing daughters, leucorrhoea may lay the seeds of many futiu'e troubles de- pendent on pelvic relaxation ; and, still more important, that it means in every case something wrong with the hygienic condition, which may or may not be capable of removal. The conditions of food, air, sleep, exercise, and clothing, must be referred to her medical adviser, and his advice must be followed as closely as possible. If of the poorer classes, she must see what can be done to alleviate her daixghter's hours and conditions of work ; if of the middle class, she must not allow her, except under dire necessity, to emulate the system of cram which is sapping the health of oiu- young men who aim at professional life in this country. When the profession of teaching, as now conducted, lies before a young- woman, I feel powerless to advise ; we must look at it as we do at other unhealthy occupations which are to be followed for the good of the com- munity, and mitigate its dangers as we can. But iu all other cases, the highest possible education of woman is only attainable by the prolonga- tion of the period of girlhood, and is irretrievably injured by ignoring the physical necessities for rest and relaxation which the period of adolescence in woman demands. Tumours or Morbid Growths, Caxcer. Cancer of the vagina is not often met with as a primary affection. It is more frequently an extension from the vulva or the utenis. Epi- thelioma is undoubtedly the most common form, although infiltration downwards of other forms is encountered. The original site is, however, sometimes in the vagina itself, the disease assuming the soft papilloma- tous form ; but it is necessary to remember that in the vaginal wall, as (•VSTS. 121 on the cervix uteri, red papillomatous growths are sometimes, though rarely, seeu, which to the eye may seem lualignaut, but which do not appear to have any histological characters of malignancy, and which do not retiim after removal. Sarcoma must be excessively rare, except as an extension from the uterus. Symptoms. — Pain, haemorrhage, and foetid discharge, characterise vaginal cancer, as they do cancer in other parts of the genital tract. Nothing but inspection, however, can make its existence certain. The same remarks as to treatment apply here as in the case of cancer of the vulva (p. 46). If there is any possibility of getting beyond the bound- aries of the disease with safety, immediate removal by cautery, knife, ecraseur, or escharotics, is desirable. If large bleeding excrescences exist, they may be scraped off, and their site treated with one of the strong escharotics, with the hope of temporarily alleviating symptoms ; and such relief often lasts much longer than might be expected. When the disease goes on continuously, especially that form which consists of infil- tration from above, and the patient survives long enough, perforation of the septa between the vagina and bladder or rectum sooner or later takes place, and fistulous openings are formed, which are, of course, not amen- able to surgical repair. There can hardly be imagined any form of more utter misery than that which is thus caused, and if ever " euthanasia " were allowable, it would be in such cases. OiDium and skilled nursing are our only resources. In some cases of malignant rectal fistula, left lumbar colotomy has been performed with considerable temporary relief. Cysts. Cysts of the vagina, like those of the vulva, have various origins. In some instances they may commence as small extravasations or thrombi ; in others they are due to the occlusion of noruuil ducts, and retention t)f their contents, which are more or less changed. The presence of follicles in the vagina is denied by some, while most WTiters unhesitatingly speak of them as soi;rces of cystic growths. The canals of Gartner, also, or rudiments of the original Wolffian bodies, are mentioned as not infreqi;ently the origin of cysts ; Imt inas- much as these rudimentary structiu-es are rarely to be found at all in any other form, this would appear to be at least problematical. The glands of Bartolinus, when their ducts are occluded, may enlarge up- wards, and so appear as vaginal rather than vulvar cj'sts. Occasionally, cysts are developed on the surface of the lower part of the vagina, vary- ing much in strength and thickness of wall, and these may become so pedunculated as to be described as hollow vaginal polypi. Symptoms. — Small vaginal c\'sts may be discovered by accident only ; but when they acquire notable size, they give rise to considerable 122 SOLID TUMOUES. irritation and vaginal cataiTh, and occasionally to heemorrliages. They may completely block up the passage, so as to prevent or impede urina- tion, coitus, or delivery. Mistakes, and very important ones, have been made in the way of diagnosis. These have arisen from forgetfulness that any part of the vaginal Avail itself may bulge forth, and that the soft tumour thus j^roduced contains, not a cyst, but a hernial sac of bladder or rectum, or even, though rarely, of Douglas's peritoneal pouch, with some of the softer contents which we have noted (p. 7) as sometimes occupy- ing it. All such hernial protrusions of the vagina — cystocele, rectocele, enterocele, (fee. — can, with a little care, be easily replaced, though they may speedily return ; and there is no true fluctuation to be obtained in them. Such mistakes in diagnosis must imply carelessness rather than want of knowledge. As regards treatment, puncture, and removal of the contents by aspira- tor, is nearly ahvays the first resource. Refilling may not take place, but it usually does, so that it is advisable, if the boimdaries of the cyst can be made out, to remove a small portion of the wall, and by iodine or car- bolic injections to j)revent refilling, and promote healing with as little suppuration as j^ossible. In deeply seated cysts, the aspirator should always be tried first. Complete removal of the cyst wall by dissection is seldom possible, unless it is small and superfcial. Solid Tumours. These are much more rare in the vaginal wall than cystic growths, but fibroids (fibro-myomata), similar to those of the uteinis, and even solid sarcomata, have been described. The extirpation of such growths, unless small or pedunculated, would be a formidable matter, and would require special study in each individual case. I have only met, five years ago, with one exaniple, which I believed to be a fibroid, nearly as large as a hen's egg, in the posterior wall. It certainly was very hard, it was -not in Douglas's pouch, nor in the rectum, and it had no connection with the uterus. I let it alone, and I feel siu'e that if it had given subsequent trouble I should have heard of it. Tubercular Deposits. These may just be mentioned as occurring, very rarely, in the vaginal wall, in conjunction with similar deposits elsewhere; and, once for all, I may say that I make no pretence, in a work of this kind, to mention every rare pathological curiosity, which a diligent search amongst authorities could unearth. There is such a thing as perspective, applicable to the relation of clinical facts, otherwise the well-known plan of the writer on Chinese metaphysics might be adopted, — look iip the names of all the organs of FOKETOX BODIES, 123 the body, then the titles of every form of nco-plasm, add the two ingi-e- dients, and the description \vo\ild be complete. Foreign Bodies. At one time 1 frequently had ditticulty in removing pessaries from the vagina, and this was due to the common use of hard wooden balls or ovals for the pm-pose of supporting the uterus. The strings attached to them rotted away, the balls jjerhaps gave rise to no immediate discom- fort, and in elderly women might remain for many years. Sooner or later, however, ulceration, or great irritation, and vaginitis, came on, especially if the pessaries were crusted with urinary salts. Deep vilceratiou some- times invaded the bladder or rectum, but this accident is quite as likely to occur from the neglect of a much more scientific instrument, the Hodge pessary. No one should ever introduce one of these, or indeed any kind of pessary, ^vithout warning the patient that every now and again, or on the occurrence of any unusual discomfort, the instrument should be seen to by a competent practitioner. For the extrac- tion of these balls, which happily I now rarely see, a small, straight midwifery forceps was often necessary, — there was no other way of seizing the rotatory substance. Sometimes, from long-continued vaginitis, the canal below them had contracted very much, and great care was required in extraction. Other bodies have been found, from time to time, introduced into the vagina, either maliciously or by the patient herself. A very long list of such articles might be culled from the medical journals, varying from pewter pots {Lancet, 1848, i. 313) to pins. Poisoning, also, has been attempted, and executed, through this channel ; but this hardly conies within our domain. No special rules can be laid down for the removal of such miscellaneous articles. An- aesthesia will often be required for the diagnosis of their shape and relations, and if projecting parts oppose themselves to extraction, they must either be broken by bone forceps and removed separately, or tlie whole must l^e turned into a more fa^•ourable position. Tact, patience, gentleness, and common sense are much needed, especially wlicn the ofTending body is of glass or crockery. Wounds, Ulcerations, and Fistulae. Wounds. Wounds of the vagina, not due to labour or to some operative pro- ceeding, are by no means common, yet they sometimes occur as the result of accident or wilful injiu-y. Thus the pitchfork in the hayficld, 124 WOUNDS •ULCEEATIOXS FISTUL^E. the goring of a bull, sitting upon cracked pottery, the breaking of a glass syringe, "wilful stabbing or kicking, rude attempts at criminal abortion, or even a sudden fall, have all been knoA^Ti to produce iTipture of the vagina. If the rent is considerable, the danger from hsemon-hage is great, and, indeed, very small wounds of the lower part may give rise to speedily fatal results. If the instrument penetrates beyond the walls, we have the further danger of ruptured or prolapsed intestine. The treatment of such Avounds requires the use of ordinary surgical means. The edges are to be brought together while fresh, and united by the in- struments and means which are applicable to the treatment of fistulse. In case of haemorrhage, pressure may be made on the lower parts of tbe vagina by the solid plug of Sims's glass dilator, but not, of course, if there is danger of internal bleeding. Great care must be taken to look for and examine any protrusion, and to return it if uninjured ; but if serious rup- ture of bowel has taken place, or if there is reason to think this highly probable, the sm'geon should not hesitate to open the abdominal cavity, and, with all antiseptic care, to search for the rupture, and repair it by gut sutures, while carefully removing from the peritoneum every vestige of escaped feecal matter. There is a great futiu-e for abdominal surgery on the hues so admirably portrayed by Marion Sims in a series of articles in the Brit. Med. Jour, for 1881, vol. ii. The great fear is that "fools may rush whei-e angels fear to tread," and bring into discredit, for a time, what promises to confer so much benefit on mankind. Ulceratioxs. Ulceration of the vagina, from cancer or other causes, has been already casually referred to. When the disease is inevitably progTessive, there is, of course, nothing to be done in the way of repair ; when such is not the case, as in ulcerations after delivery, openings occur into the sur- rounding hollow viscera, and the whole matter will be best considered under the heading Fistulse. Fistula. Causes. — These may result from clean wounds, such as have been mentioned above, — rarely so, however, if they have been under skilful treatment from the first. Malignant fistulee may be dismissed at once as beyond the reach of art. Abscess in the pelvic cellular tissues may, by burrowing in two directions, connect the vagina with the bladder, the rectum, or the perineum; and the same may be said of those extravasations of blood already described as thrombi, or afterwards to be spoken of as pelvic hsematocele, but only in the event of their suppurating. The idceration produced hj a pessary or other long-retained foreign VAGINAL FISTUL.E. 125 body in the vagina ma}' lay open the rectum or bladder. Syphilitic sores may also perforate the vaginal wall, but it is iisually the urethra that is thus entered. Ulcerative perforation of the vagina may alsc) occur from without, as from the presence of a hair-pin, or a calculus, in the bladder ; and foreign bodies in the rectum, even hardened faeces, may produce the same result. Chronic vesical ulceration, without any foreign irritant, has been traced in some instances as a cause of vesico-vaginal fistulae {Lancet, 1870, ii. 738). Artificial fistvila has also been advocated and performed by Bozemann, Emmet, and others, for the cure of some vesical affections (.see Chap. XXL). Sloughing of the vagina, with sub- sequent fistula, in the course of eruptive fevers, has also occurred ; and, as we shall see shortly, congenital malformations may also cause communications between the various pelvic viscera, which, if they do not produce one great common cloaca, may be so limited in area as to be regarded and treated as fistulte. But all these causes put together, except the malignant ulcerations, do not create a tithe of the number of the fistulee which are due to misfortime or mismanagement in the process of labour. In some instances the par- turient canal gives way, and at once produces a communication of viscera. Such is the case when the perineum yields, and with it a portion of the recto- vaginal septum, although strictly speaking this can hardly be said to produce a fistula till the perineum has healed. ]\Iore rarel}', — fortunately much more rarely, — the upper part of the vagina gives way, either by itself, or following the line of a ruptiu-e in the cervix uteri. But the great majority of vaginal fistulse, of puerperal origin, are not immediately pro- duced, but are due to subsequent sloughing fi-om severe or long-continued labour without skilled help. That the forceps, or still more readily, craniotomy instruments, may, in skilful hands, produce rupture, I am not prepared to deny, but in the great majority of cases it is the delay in using these instniments, or the using strong traction after the head has been allowed to become thoroughly impacted, which is answerable for the result. Fortunately, we are almost all now agreed on this point, but it was not always so. "What unskilled use or neglect of obstetric instniments may do, Emmet and other extensive operators on vesico-vaginal fistula- have taught us. The sloughs produced by prolonged pressure may come away in a day or two, or they may be delayed for a fortnight, or even more, but usiually the mischief is apparent in three or foiir days. The part of the ])arturient canal aftectcd by the pressure, and consequent sloughing, is influenced in various ways, but it is usually that portion which happens to lie between the licad and the pubic symphysis at the time of gi-eatest or longest pressure. Thus the part in rear of the bladder is most frequently affected, but the urethra may be dragged up into this situation, or the anterior lip of the cervix uteri may 126 CAUSES OF VAGINAL FISTULA. be pushed down and caught there. The comparative shortness and inflexibility of the anterior vaginal wall is also not without its influence in determining the seat of rupture. The varying situations of fistulfe, anterior to the vagina, are thus accounted for, but recto-vaginal fistulse are more commonly due to direct rupture than to sloughing. It may be well to shoAv at a glance the various causes of vaginal fistulse— 1. Incised or piuictured wounds. 2. Cancerous ulceration. -3. Pelvic suppuration. 4. Syphilitic ulceration. 5. Pessaries or other foreign bodies in the vagina. 6. Vesical calculi. 7. Foreign bodies in the rectum. 8. Foreign bodies in the bladder. 9. Chronic vesical ulceration. 10. Sloughing during fever. 11. Congenital malformation. 12. Direct tearing in labour. 13. Slouo-hing after labour. It is not necessary to dwell on the symptoms prodviced by these fistulse. The symptom is the escape per vaginam of urine, faeces, or flatus. This may vary in extent, according to the magnitude and position of the fistula. In recto-vaginal fistulse the faeces may continually escape, except when constipation exists in the very highest degree, or this may only occur during diarrhoea, or nothing except flatus may pass. In anterior fistulse the escape of urine is a more constant symptom, even when the aper- ture is small. Especially will this be the case if it is situated just behind the urethra. But there may be some power of retention, as for instance when a portion of the urethra only is involved, and not the bladder, or where the aperture in the bladder is so situated as to be above water mark, either in standing up or in lying down, when the bladder is only partially full. More rarely, the opposite wall of the bladder may bulge through the opening in such a way as to form a sort of plug, until more complete filling of the organ separates its walls. The patient's life is always a miserable one ; and to add to the above-named symptoms, which cause infinite discomfort, there is always some accompanying vaginitis and vulvitis, and the external parts become inflamed and ulcerated, or covered with eczema, and subject to pruritus. The removal of these secondary symptoms, previous to operation, affords no mean element of success in the operation itself. Diagnosis of the exact condition is often more difficult than might be imagined. I have come across more than one supposed urinary fistula which has proved to be nothing more than incontinence, and Avhich has yielded to the use of strychnia and the constant galvanic current. The finder will generally detect and gxiide iis to a fistula of any size ; but in the case of small openings, single or multiple, the most careful and pro- lono-ed, perhaps repeated, examination may be necessary. The tubular and duck-bill specula may i^e used in turn ; but no matter which of these VARIETIES OF FISTUL^E. 127 first shows the opening, the latter will be recj^uircd to bring it fully into view, and within reach. A wide but short tubular speculum, or a duck- bill, with a fenestra an inch wide in its walls, are either of them very serviceable in detecting rectal fistulse, and in inserting su.tures in them. The duck-bill is hardly impaired for its other uses by this fenestra. In small vesi co-vaginal fistulse, or when there is reason to think that the posterior opening is uterine rather than, or in addition to, a vaginal one, the injection of fresh milk into the bladder, while the vagina is exposed, is an excellent aid to diagnosis. The white oozing fluid is at once apparent to the eye. There is hardly any department of surgery in which such great im- provements have been made of late years as in the operative treatment of these affections ; and for this improvement, although many great writers, English, continental, and American, have contributed a share, we are mainly indebted to Marion Sims, who, by the introduction of his speculum and of silver sutures, alone made all the rest possible. Emmet, while giving full credit to his distinguished countryman for these improvements, points out that in mere priority he was forestalled in both ; such was also the case with the introducer of the sound and the tent, and this gives point to Emmet's remark, that "ideas and general principles may be new, but mechanical procedures seldom are." Although I shall have little or nothing to say here of the surgical treat- ment of the more rare forms of fistulae, and will chiefly confine myself to mentioning the principles which guide us in the treatment of the common forms, but which are applicable, with special modifications, to all, yet it may be advisable to place in a tabular form the varieties which such fistulse may assume. The names of the fistvilse are in them- selves sufficiently descriptive of the organs communicating : — 1. Vesico-vagiual. 2. Vesico-uterine. 3. Vesico-utero-vagiiial. 4. Urethro-vaginal. 5. Uretero-vaginal. 6. Uretero-rectal. 7. Vesico-rectal. 8. Recto-vaginal. 9. Entero-vaginal. 10. Recto-labial. 11. Perineo-vagiiial. 12. Pcritoiu'o- vaginal. Of these it will be observed that several (2, G, 7, and 10) arc not fistukc of the vagina at all ; but their mode of origin, of diagnosis, and of treat- ment is so closely allied, that it seems better to include them in one table. Some of these fistula) are also so rare, or their treatment is so exceptional, that they may be at once dismissed. These will include the fistula) into the ureters, the recto-vesical fistulsc, where the vagina has escaped injury, the involvement of the intestine rather than the rectum, and the recto-labial fistula, a mere accidental vai-icty of the recto-vaginal ("), G, 7, 9, 10). The peritoneo-vaginal (12) is a form of fistula which, 128 VAEIETIES OF FISTUL.E. • a priori, one would hardly consider as permanently consistent with life. I had, however, at one time, the opportunity of carefully examining a case recorded by Mr Walter Whitehead (^rjY. Med. Jour., Oct. 1872), and referred to by Barnes (Diseases of Women, p. 461), where no trace of uterus could be found in a multiparous Avoman (it was supposed to have undergone complete super-involution), and where the sound could be passed, and was often passed, through a small orifice at the top of the vagina, and could with ease be moved about in any direction, and for any distance, and felt in close contact with the abdominal walls. Finally, the perineo- vaginal fistula (11) maybe eliminated, as differing from the others in not connecting two canals or internal viscera. In its nature it is similar to fistula in ano, and I have seen them coexistent, and apparently without intercommunication. Nothing but the greater vascularity and com- plexity of the parts about the vulva, and the fact that spontaneous healing can be more readily trusted to, prevents the adoption of similar treatment as in fistula in ano. I will merely indicate here the lines of treatment in a case of ordinary vesico-vaginal fistula, referring also to the occasional involvement of the uterus or urethra, and adding anything which may be required to elucidate the treatment of recto- vaginal fistulse (1, 2, 3, 4, 8). Supposing, then, that a moderate-sized rent is discovered between the vagina and bladder, Avhat are the probabilities of spontaneous cure, or cure without operation? Not very great, certainly, but not entirelj- hopeless. At any rate, the same measures are required for the comfort of the patient as those which give the best chance of spontaneous cure. A small sigmoid catheter (fig. 67), or a Skene-Goodman catheter (fig. 68), should be introduced and retained in the bladder. The vagina must be frequently s}Tinged Avith warm Avater containing 1 in 40 of carbolic acid, and the patient must be kept as quiet as possible AA'hile recovery from jDarturition is going on. As that period passes by, the injection may be used hotter and hotter, and the other means are emjDloyed which are required as preparatory to operating in chronic cases (see Chap. III.). Spontaneous cure may occur in this AA^ay, though it rarely does with acci- dental fistulse. As an aid to cicatrisation, the actual cautery is noAv almost entirely out of date. Very small rectal fistulte may heal under its influence, though stitching is probably better, even in these ; but A^esical fistulse, eveia mere pin-hole apertures, Avould probably heal spon- taneously, under careful general management as aa'cII as AA'ith the use of the cautery. There is a tolerably smart contest between some German authorities — Simon, for instance — and those of the school of Marion Sims and Emmet, as to the A'alue of the metallic suture, of careful preparatory treatment, and as to other and less important points, and it is not for those PREPARATIOX FOR OPERATIOXS ON FISTULA. 129 who ajiproach gynsecology froui the medical rather than tlie surgical side to decide judicially between such eminent disputants, but the humbler function, analogous in some -wayn to that of the jury, is open to us, and on the two points mentioned, the great value of silver wire, and the necessity of very careful prej)aration of the patient, I feel compelled to find an affirmative verdict. In following very closely the lines laid down by Emmet for closing these fistulse, I am only doing what others liave done, not always with similar acknowledgment. The preparation of the patient, then, for operation furnishes an element of success which should never be lost sight of. As a result of the abnormal direction of the urinary flow there very speedily forms a deposit of phosphatic sediment around the fistula and encrusting the vaginal w^all. Hence w-e have concurrent vaginitis, the combined dis- charges causing eczema of the external parts, together with abrasions and ulceration of the vaginal wall, vulva, and thighs. This condi- tion must be removed, if it has been allowed to occur. With a soft sponge all deposits miist be wiped away, at one or more sittings. All raw surfaces should then have applied to them a weak solution of nitrate of silver. For several days the vagina is frequently syi-inged with water, as warm as the patient can comfortably bear it, and the addition of carbolic acid (1 in 40) is advisable. The external parts must be kept free from irritation by the application of vaseline. The urine, generally alkaline, must be restored to its normal acidity, for which purpose Emmet recommends the following formula : — R Ac. Benzoic. 3ii, Sod. Bor. 3iii, Aq. gxii. St. gss. ter die, ex aquae cyatho. This plan of treat- ment must be continued for days, or weeks, until the parts have acquired their natural appearance, an occasional touch of nitrate of silver or tincture of iodine being given to excoriations which are obstinate. There is no doubt that success is often obtainable hj skilful surgeons without these precautions, and it will be infinitely better if, by attention to the patient from the first, they are hardly required. But under this treat- ment spontaneous healing does occasionally occur, as it does in spite of the surgeon, in the case of clean artificial fistula; made for the cure or relief of bladder disease ; and few who have seen a vesico-vaginal fistula in its neglected state, and compared it with one thus attended to, can doubt that the chances of spontaneous healing or operative success are both greatly improved. Another preliminary, not always, but often, required, is the division of cicatricial bands which prevent the edges of the fistula from being easily approximated and united without imduc strain. Such bands, if slight, may be snipped with scissors at the time of operation, but if strong or extensive this should be done as a preliminary operation. The resulting haemorrhage must be stayed ])y hemostatic astringents and the pressure 130 ' THE OPEEATION FOE of one of Sims's dilating plugs, and a week or ten days is allowed to elapse, during which frequent carbolic syringing and the occasional introduction of the glass plug should be employed. For the operation, three assistants at least are required, one to take charge of the anaesthetic, another of the duck-bill speculum, and a third of the other instruments, sponges, &c. This latter must be trained to keep his fingers out of the way and himself out of the light. The patient having had the bowels well cleared, and a dose of opium administered, is anaesthetised, and placed in the lateral prone position. The duck-bill speculum is introduced, and the fistula brought as well as possible into view. The genu-pectoral position is rarely necessary. The lower border of the fistula is then seized with a tenaculum, or a long finely-toothed forceps, and a strip of vaginal mucous membrane, one-fourth to one-sixth of an inch wide, is carefully removed all round the orifice, leaving the vesical mucous membrane intact, but paring close up to it. This freshening should extend well beyond the angles of the wound, in order to pro- vide against the possibility of a small fistula remaining at those points. When the septum is very thin it may be difiicult to obtain a sufii- cient raw surface, and it may be necessary very carefully to split the layers between the vagina and bladder, making the non-mucous surface ot each to play a part in the new cicatrix. Those who have been privileged to see Marion Sims operate with the small razor-like knives, capable of being set at any angle in a long handle (fig. 46), would be tempted to under-estimate Fig. 72. -Paring Fistula by the difficulty of using such an instrument with Scissors (Churchill et pq-xxj- i ^ ■■,. . Lebloud). sutlicient steadniess and skill, bxit m ordmary hands the use of sharj) scissors is preferable (fig. 72). A variety of scissors curved in various ways would form part of the armamentarium of a specialist operating on any large scale, but figs. 73 and 74 show two of Emmet's favourite forms. It will depend on the skill of the operator, and the accessibility and size of the fistula, whether sufiicient membrane can be removed in one long strip, or whether fresh hold will have to be taken and the paring done at several strokes. If the vesical mucous membrane has been cut it is apt to bleed freely. This may be checked by seizing the bleeding edge with a torsion forceps which is allowed to hang for a short time, the delay being otherwise not disadvantageous. If that fails, a ligature of gut may be passed through the vaginal wall into the bladder and out again at a very short distance from the raw edge, so as to encircle the VESICO-VAGINAL FISTULA. 131 bleeding vessel. Such ligatures must uever be placed far, say not more than half an inch, from the middle line, or they may involve the ureter. In the case of a large opening they could never be free from this danger. The wound being now pared, its edges must be united so that the raw surfaces will be in accurate contact. Pure silver wire is certainly the best for this purpose. For their introduction most men could, I think, easily manipulate laterally curved needles with fixed handles (fig. 48), and with their edges rubbed down so as to make them as nearly round as possible. Tubular needles (fig. 49) with a lateral or double curve are apt to fail, from the wire refusing to pass. Emmet, however, and others prefer to use short, round needles, from one-half to three-quarters of an inch in length, slightly curved at the point, which are introduced Fig. 73. — Emmet's Curved Scissort Fig. 74. — Emmet's Double Curved Scissors. by means of a needle-holder, carrying with them a loop of silk. This loop is used to draw back through both sides of the fistixla the end of a silver wire hooked round it. The space between the stitches should be about one-sixth of an inch (fig. 75). All the necessary stitches having been placed, and a little time being given to allow oozing to cease, which cessa- tion may be accelerated by the application of a little pure spirit, tlie bladder should be washed out with a gentle stream of warm water, directed through a catheter, and allowed to escape at the wound, and the edges must now be approximated. Simple twisting of the wire is sufficient (fig. 60). The twisted ends are then cut oft' about half an inch from the wound, and bent over laterally to alternate sides. A small self-retaining catheter is introduced, and the same precautions as to aft-er-trcatment 132 OPERATIONS FOR VESICO-UTERINE, must be observed as in all other operations of this kind — very light nutritious food, and opium to lock the bowels for a very few days, and to keep the patient at rest. The stitches should remain for eight or ten days, and should be removed with the greatest possible gentleness, the catheter being used for some time subsequently. When the vesico-vaginal tear implicates also the cervix uteri, any operation for its closure becomes still more difficult and complicated, but must be conducted on the same lines. It not unfrequently happens, however, in such cases, that partial spontaneous reparation takes place, leaving two separate fistulse, one into the vagina, the other into the uterus, or perhaps one only into the cervix uteri. This can only be reached by freely dividing the cervix up to the fistula, so as to reproduce, to a cer- tain extent, the original tear through it. When the urethra is the part involved in a vaginal fistvila, the facility of repair- ing it is greater than in the case of the bladder, so far as getting at it is concerned, but the intervening tissue to work upon is excessively thin. It is therefore recom- mended, after freshening the edges on the vaginal side, to relieve the tension by a longitudinal incision, paral- lel to the borders of the repaired fistula. The fistula is kept well in view during operation by retaining a full sized gum- elastic catheter in the urethra. I am inclined to recommend, in this case, though from little personal experience, the use of fine gut sutures, which may be left for a longer period than wire ones, or indefinitely. Recto-vaginal fistulfe have been already referred to in connection with the subject of torn perineum. As a result of this accident, with sub- sequent union of the perineal tear, and also as an occasional result of abscess or syphilitic ulceration, they come as frequently imder the notice of the general medical practitioner as vesical fistulse, although in some Fig. 75.— Fistula with Wires inserted (after Churcliill et Leblond). VESICO-URETHRAL, AND VESICO-KKCTAL FLSTUL.^. 133 respects they are more difficult of repair. This is owing to the greater difficvilty of bringing them steadily into view. With the finger in the rectum there is no difficulty in protruding the torn septum into the vaginal space, but to insert a duck-bill speculum with its convexity to the pubes, though it is generally looked upon as our only resource, is certainly not in accordance with the principles upon which the use of that instnxment is based. By this means, and having the labia further held open by spatulse, while the patient lies on her back in the lithotomy position, the fistula is exposed. A fenestrated speculum, through the fenestra in which "the fistula can be got at, is sometimes of service, and it is worth while to have one specially cut for the operation. When the patient has been anaesthetised, a large bougie can be easily passed into the rectum, previously well emptied by injections, and this serves to keep the fistula prominent. The mode of paring the edges and of insert- ing the sutures varies little from that followed in relation to vesico- vaginal fistulse, but the bevelling of the edges, the wider part of the tear being vaginal, is often already very great before any paring is done. In cases where there is difficulty in obtaining a sufficient raw surface, the septum may be carefully split, the vaginal layers stitched together with wire sutures, and the rectal ones with pure gut, which is left to disappear of itself. The rectal stitches should be first inserted. Dr Goodell recom- mends {o}). cit., p. 68) a more complicated process, " a shallow cut is made round the vaginal mouth of the fist\ila, about half an inch away from it, and the mucous membrane dissected up to its rim in a frill. This is next inverted and pushed into the rectum through the opening, which is now closed by rectal and vaginal stitches — the former uniting the raw surfaces of the frill, the latter the raw strip around the vaginal rim of the fistula." In order to insert these rectal sutures it is necessary to previously stretch and paralyse the rectum, and then to introduce a duck-bill speculum within it. Occlusion of the Vagina. Occlusion of the vagina may be congenital, and this state, together with its occasional consequences, will be described in Chap. VI., along with other malformations. Much more rarely it may result from injuries, or from sloughing after labour or otherwise. If complete, and if it occurs before the menopause, there will of course be reten- tion of the menstrual fluids, and operative proceedings will be re- ipiired similar to those for congenital retention. If only partial, it may still act as an inipcdinient to connection, and demand remedy. In all s\icli cases, the maxim is to do as much as ])()ssib]e l)y dilatation, and as 134 ACCIDENTAL AND ARTIFICIAL OCCLUSION. little by cutting. If anaesthesia is used, the parts yield readily and betray the points of greatest tension. These should be carefully snipped with scissors, and the glass dilator used for the pui-pose both of disten- sion and of arresting haemorrhage. In this way it is astonishing how little cutting of the surface enables the vagina to unfold to its former calibre. Artificial occlusion of the vagina is recommended in the case of large or incurable fistulee, and its adoption will, of course, depend, to a very great degree, on the presence or absence of menstruation, and on the marital relations. ]\Ienstn.iation is, however, no absolute barrier, as in such cases the fluids will find their way by the rectum or bladder. The former would be the more satisfactory outlet, owing to the danger of cystitis and accumulation of clots in the bladder ; but I have recently had under notice a case (fig. 82) where the vagina is congenitally absent, the much retroverted uterus opens directly into the bladder, and men- strual life has, so far, about five years, been unattended with any diffi- culty, except for one or two jjeriods after my first diagnosing the case by passing the uterine sound j'jer urethram. As a matter of fact, now-a-days, vaginal rents very seldom indeed de- mand total occlusion of the canal ; and, with the modem improvements in operating on fistulse it should be but a last and rare resource. The surfaces chosen for freshening and attachment will vary, of coui'se, according to the exigencies of the case and the amount of sound tissue remaining ; but, as a rule, it will be foimd better to unite the anterior and posterior walls than the lateral ones. Paring and iniiting of the vulvar surfaces would, a priori, appear to be a comparatively easy matter, but it has been found practically to be almost impossible to avoid some fistulous opening in the neighbourhood of the urethra, which destroys the effect of the whole operation. Prolapse of the Vagina. This has already been mentioned in connection with torn perineum. It seldom exists to any great extent quite independently of that, but may do so. Its causes, its symptomatology, and its treatment are so inti- mately associated with those of the same affection of the uterus, that it will avoid much repetition if we consider them together (see Chap. XI.). CONGENITAL MALFORMATIONS. 135 CHAPTER VI. €oxGENiTAL MALFORMATIONS OF THE Genital Tract. Ovaries and Fallopiau Tubes, Uterus, Vagina, and Vulva. Hermaphroditism. Results of Atresia, and Proceedings for its Removal. It seems advisable to mention in one place the congenital malforma- tions which are met with in the various portions of the genital tract. Many of these abnormalities are, of course, quite incurable, and bear solely on the question of viability, or of marriage or sterility, but others -are of great practical importance, leading to the retention of the pro- ducts of menstruation, and thus causing painful and dangerous affections which are fortunately within the reach of ai't. The Uterine Appendages. Under this heading we include the ovaries and Fallopian tubes, although from another, and perhaps more strictly scientific point of view, the uterus, vagina, and Fallopian tubes might rather be con- sidered as the appendages, or at least the diicts, of the ovaries. Malfor- mations of the latter organs, as a rule, exist only in connection witli malformations of the uterus, but they may exist separately, and are doubtless sometimes the hidden and obscure causes of menstrual and ■other diseases. When the uterus is absent, or practically absent, being- found only in the most rudimentary form, it is rare to have the ovaries present, yet cases are recorded where, in the absence of any recognisable uterus or vagina, there occurred an undoubted menstrual molimen, and the pathological theatre shows that in such cases one or both ovaries may exist in a less rudimentary form than the uterus. The occuirencc «of a monthly molimen imder such circumstances would therefore warrant us in l)elieving in their existence, although we were unaV)lc U> detect them by physical examination, but in tlie absence of an increasing tumour, caused by the accumulation of the monthly secretion, whicli would imply the presence of a uterus of some size, or if there were no signs of intra-pelvic haemorrhage, it would hardly warrant us in any attempt at surgical interference. I can imagine, liowever, thoiigh I have never seen, such an amount of ovarian troiiblc, with complete 136 CONGENITAL DEFECTS IN THE OVAEIES, absence of vagina and utems, as might warrant an attempt to seek for and remove by abdominal section the now redundant and harmful glands. Peaslee operated in a case of this kind, but with fatal result. Independently of absent utems, one or even both ovaries may be ab- sent from foetal disease. Klob and Rokitansky have attributed this in some instances to twisting of the ovarian attachments, whereby the ovary was slowly strangled, atrophied, and completely obliterated. This is somewhat analogous to what occurs occasionally to the mature ovary when the subject of cystic enlargements. In the dissecting-room, a supplementary ovary has also been occasionally found, originating in a mere accidental fissiparous division of that of one side during early development. If the operation of oophorectomy assumes as prominent a position as it at present threatens to do, such abnormal structiires may yet be encountered in the living subject. Hernia of the ovary through the canal of Nuck, the representative of the inguinal canal, and appearing either at the external ring, or in the labium, has already been mentioned, and if not a congenital phen- omenon, the condition of parts which allows of it is so. Its first re- cognition may be due to an attack of ovaritis, and this is apt to become chronic, or recurrent to such an extent as to necessitate the removal of the organ, reduction being then seldom possible, and after a time hardly advisable. Most commonly, however, an operation has been undertaken for hernial obstmction, and the ovarian contents have only then been discovered. Tait gives a fuU summary of such cases as he has been able to trace {Diseases of the Ovaries, 1883). A distinct swelling of such hernial ovaries is noted at the menstrual periods. Hernia of the ovary elsewhere has been described, but chiefly as a post-mortein phenomenon. Prolapse of the ovary into Douglas's pouch will be afterwards noticed (Chap. XV.), and it is usually an acquired and not a congenital condition. The position of the ovary in hermaphroditism or pseudo-hermaphroditism may be very various. The ovary, though existent, may also be an-ested in any stage of its develop- ment, either with or without a similar arrest in the uteiiis, but most commonly this arrest coexists with what will be described as infantile uterus (Chap. VIIL). The combination of these two arrests in develop- ment is a fertile source of menstrual derangement and difficulty, and may lead to nervous affections — hysteria, epilepsy, and hystero-epilepsy. It was for this condition, and to cause by its local irritation a tendency to fuller development of all the organs, that Simpson introduced tlie galvanic stem pessary into the uterus. Of the congenital defects of the Fallopian tubes little is accurately known, although a fuller knowledge of them would be of the greatest value, seeing that the investigations of Lawson Tait have rendered it FALLOPIAISr TUBES, AND UTEKUS. 137 probable that these ducts play a more important part in phj-siology and pathology thau has formerly been assigned to them {Brit. Med. Jour., vol. i., 1881). In his recently published work on diseases of the ovaries he intermingles his remarks on the congenital and acquired abnormalities of these tubes, so as to make it a little difficult to ascer- tain what ftxcts he has personally obtained, or culled from other sources, on the subject of the former. But I gather that congenital tubal abnormalities sometimes do, and sometimes do not, coincide with similar developmental conditions of the ovary, and that a not uncommon defect lies in the relative position of the ovaries and tubes (fig. 78); sterility, and I would suppose tendency to htematocele, therefrom resulting. I cannot ascertain whether he considers that the occlusion of these tubes at both ends, and their consequent distention into cysts, is often a de- velopmental defect, or one nearly always dependent on inflammatory adhesions. Probably it is too miich to ask from any present observer. Closure of these canals at either end is not uncommon from gonorrhoeal or other inflammatory extensions, leading to accumulation of their con- tents, abscess, or hsematocele (Chap. XVIII.). The Uterus. The key to nearly all the congenital derangements of the uterus and vagina lies in the fact that they are formed in early foetal life by the coalescence of the two Mllllerian ducts. Most of the recognised malfor- mations ai'e thei'efore traceable to insufficient, or excessive, or unequal union of the two sides, or to imperfect development of either half or of both. The uterine portion unites later than the vaginal, and the Fallopian portion remains permanently ununited. In the following brief account of these malformations it is their practical bearing upon the health and comfort of the patient which is held in view, rather than the anatomical interest of the matter. Absent Uterus. — Clinically speaking, this is not extremely uncom- mon ; that is to say, a condition of matters exists in which no uterus can be discovered by examination of the living subject. In the dissect- ing-room, however, some trace of the organ can generally be found in such cases (figs. 76 and 77). Menstruation is, t)f course, absent, altlK)ugh we have seen that some moliuicn may be })rcsent, dei)cudent on tlic more or less perfect state of the ovaries and Fallopian tubes. The vagina also is often absent, or exists only as an imperfect canal. Every ex- ternal ajjpearancc of womanlujod may be present, but the finger in the I'ectum, aided by abdominal })rcssure, or by the presence of a sound in the bladder, detects nothing like the usual uterine body. A very small 138 ABSENT UTEEUS UTERUS UNICORNIS. Fig. 76. — Rudimentary Trace of Uterus (Schroeder). u, uteru.s. hardish substance may sometimes be felt centrally, or at either side, but practically it may be set aside as only possibly denoting some rudimen- tary stage of uterine development, of no clinical importance. The traces which are discovered on dissection are found on the posterior surface of the bladder, there being but one pouch of peritoneum between the bladder and the rectum, as in the male (fig. 76). These traces may consist of either a simple transverse band or bow, representing the two conjoined halves of the body, with- out cervix ; or there may be a small substance, hollow or solid, somewhat resembling the uterus in shape, and with or without separate horns (fig. 77). Uterus TJnicornis, or one-sided uterus (fig. 78), depends on the arrest of development of one of the two Miillerian ducts. This condition is compatible with perfect menstrua- tion, and even pregnancy. It is difficvilt and often impossible to diag- nose it during life ; but it may be sur- mised if we meet with certain conditions, VIZ., a narrow vagma (unilateral in develop- ment), a small cervix, and a uterus which is shown by sound and bi-manual examina- tion to be unusu- ally bent to one side, having a somewhat sharply-pointed fundus, and sometimes an unusual length. All other causes of uterine elongation or lateral displacement must be capable of elimination ; and, considering the rarity of the affec- tion, and the many sources of error, the diagnosis must be held subject to revision. How many errors would be avoided if the practitioner would acquire a habit of mentally noting, and carefully remembering, which of his diagnoses were merely provisional ! The undeveloped half may consist of a mere band of fibro-myomatous tissue, or may contain a small cavity, or an elongated tube, opening within the more developed one at any point, or with no outward opening at all. If pregnancy occur in the fully developed side, all may go well ; if in the undeveloped one, early abortion may fortunately occur, or towards the middle of Fig. 77. — Rudimentary Uterus (Schrceder). a, uterus ; h uterine horns ; c, round ligaments ; d. Fallopian tubes e, ovaries. UTERUS DUPLEX. 139 pregnancy rupture may take place, with all the phenomena and gene- rally fatal results of a so-called interstitial extra-uterine pregnancy, or a premature and a perfect foetus being born together, or near the same time, may add to the recorded but doubtful cases of super-fcetation. While these pages Avere going through press, I have met with an interesting case of a Fig. 78. — Uterus Unicornis (Scliroeder). LH, left uteriue horn ; Lo, left ovary ; LT, left Fallopian tube ; LLr, left round ligament. RH, Eo, RT, and RLr represent the corresponding structures on the right side. The relative positions of the ovaries and tubes are abnormal. ladj' attacked since marriage with membranous dysmenorrhoea. She herself (the wife of a medical student) observed that one horn of the decidua was always much longer than the other, and this led me to clearly make out the signs of u.terus unicornis in a minor degree. Uterus Duplex, double uterus, or Hysteros Didelphys, are the terms applied in the case where both Miillerian tubes have become fully developed, forming two almost separate uteri, with little co- alescence (fig. 79). It is of exces- sively rare occurrence, except in the case of non-viable foetal mon- .strosities ; but of late years instances have been fou.nd even in women who have borne chil- dren. They arc often accompanied l)y a double vagina. A typical case of the kind is well reported by my colleague, Dr Cullingworth {Brit. Med. Jour., 1882, vol. ii. p. 387). There is no reason why, in such a case, pregnancy might not occur in cither section, or even in both, and that simultaneously. Menstruation occurs, not at two different periods, but as in the normal condition. The diagnosis, attention once called to it, would be simple if the vagina* were at all jierfcct. Uterus Duplt'x (Thomas). 140 UTEEUS SEPTUS UTERUS BICORNIS. Fig. 80. — Uterus Septus (Schroeder- Kussmaul). Uterus Septus and Uterus Bicornis constitute two varieties of imper- fect coalescence of the two primordial constituents of the organ. In the former (fig. 80) the uterus is divided by a septum, which extends down- wards from the fundus in various degrees, but externally the organ may show little or no sign of malformation ;. in the latter (fig. 81) there is a separation apparent on the outside of the organ, and varying in extent from a mere sulcus at the fundus, which evidences its bi- lateral origin, to a division which practi- cally creates two uteri with a common cervix or os externum. Combinations of these two forms may also exist, the slightly two-horned uterus having also a septum dividing the common cavity. Pathological museums probably show but a small portion of the possible or actual varieties. A single or double vagina may coexist with either of these malfor- mations ; the more complete the double character of the uterus, the greater the probability of vaginal division. Although there may be no arrest of development in the sense now treated of,— that is to say, in the lateral symmetry or central union,— there may be an arrest of developmental growth. Thus, even in the adult, the uterus may retain the- type which it has normally assumed in the infant, or, reach- ing the type of the young virgin, it may retain that, while the size may remain consider- ably under the normal. These two abnormalities, — the infantile uterus and the so-called congenital atrophy of the uterus, — are, together with the same condition of the ovary, of great practical importance, but they will be more fittingly described and discussed, when their resulting consequences are under consideration (see Chap. VIII. ). Fig. 81. — Uterus Bicornis (Schroeder). ABSENT, UNILATEIiAL, AND DOUBLE VAGINA. 141 The Vagina. The vagina, as ^ye have ah-eacly noted, is also affected by the want of due fusion between its lateral halves of origin, and arrest of de- velopment may occur in either half, or both. In the one case we have wholly or partially double vagina, in the other it is narrowed or obliter- ated. Using, as far as possible, the same classification as for the uterus, we have Absent Vagina. — Clinically speaking, this refers to cases where we have nothing to show that any canal exists between the bladder and rectum. Rudimentary structures, discernible only 2yost mortem, may be left out of account. This absence may occur either Avith a fully de- veloped uterus and appendages, or with a more or less corresponding want of development in them. But the absence may be partial confined to a portion of the vaginal canal only, and the undeveloped portion may form a barrier between the uterus and the vulva of very varying extent, from a mere intervening diaphragm to complete oblitera- tion. In all such cases, if the uterine and ovarian functions are active, we have a condition which will demand surgical interference, as we shall just now see. Vagina Unilateralis. — ^This condition certainly exists, looked at from a developmental point of view, especially in connection with the uteriis unicornis, but as the vagina in this state, owing to the distensibilitj'^ of its walls, usually fulfils all its normal functions, it is more interesting moi-phologically than practically. Vagina Septa, or complete Vagina Duplex, may coexist with the uterus septus, bicornis, or duplex, — the septum being only partial, and chiefly affecting the lower end of the vagina ; or, the two lateral organs may be perfect, communicating with their individual cervices and closed by perfect hymens. But double vagina may also coexist with a single normal uterus, one side being in all probability somewhat rudimentary. With double uterus and vagina, one vagina may terminate normally in the vulva, with perfect hymen, and the other may be occluded, so as to ■escape notice until distended witli menstrual fluid (unilateral liajmato- kolpos). The vagina may be abnormally narrow or short, witliout evidence of any other developmental abnormality. In the former case, artificial dilatation may be required sixbsequent to marriage ; in the latter, thei e is danger of uterine inflammation following connection, unless timely warning can be giyen by the ph3'sician. Finally, the vagina, perfect otherwise, may be occluded by a complete condition of the hymen, that structure, nearly always unduly thickened 142 AUTHOES CASE OF UEO-GENITAL DEFOEMITY. under the circumstances, having no orifice for the escape of uterine discharge. In double vagina, the one half is frequently rather in front of the other, and this is attributable to the fact that the left Mtillerian duct lies somewhat in front of the right. But in certain more rare uterine malformations there are traces of an antero-posterior defect in develop- ment, as well as of a lateral one. About two years ago I Avas consulted by a young woman of about twenty-three years of age on account of some vague discomforts, which led to a vaginal examination. Menstnia- tion was said to be perfectly regu- lar ; but, to my astonishment, I found complete absence of the va- gina. It speedily became clear that menstrua- tion could only occur throiighthe urethra, though there had never been any vesical discomfort, nor suspicion of a wrong channel. I had only a uterine sound at hand, but I passed it into the bladder, while I explored the rec- t\im with the left forefinger in search of a uterus above the atresic vagina. In this way the sound undoubtedly passed into a clearly-definable retroverted uterus^ which I could move freely ^jer rectum. There were some clots after this, and more irritation of the bladder than ever before. She declined to allow of a digital examination of the bladder per uretliram, and I have since lost sight of her. In this case (fig. 82), where the cervix or lower portion of the uterus opened into the bladder, it may have resembled, morphologically, the sinus pocularis of the male. And we have a reminder or survival of a former state of development, permanent in birds, where Miiller's tubes open into a common uro- FiG. 82. — Congenital Atrcesia Vaginse, Uterus opening into tlie Bladder (Author's case). DEFORMITIES OF THE VULVA. 14:$ genital canal ; and where, at a still earlier stage, this common duct opens, along with the rectum, into a general cloaca. The English student will find a clear account of the above-mentioned congenital abnormalities of the uterus in Schrceder {Ziemssen's Cyclopedia, vol. x.), who, however, together with nearly all subsequent writers, is mainly indebted to the classic work of Kassmaul (Wurzburg, 1859). The Vulva. In malformations of the vulva the antero-posterior failure in develop- ment is still more frequently apparent. Absent Vulva is found in those cases where no external opening has occurred, and where, therefore, the bladder, genital canal, and rectum have no outlet, common or separate (fig. 83). Such foetuses are non- viable, and generally monstrous in other respects. In other cases (fig. 84) the external opening is present, but the perineal septum has '>^ ^J Fig. 83. Fig. 84. Fig. 85. W^ Fig. 86. Fig. 87. Five Diagrammatic Figures, after Schrceder, illustrating stages in the development of the Genito-urinary Organs and Rectum, referred to in the present text. ALL, the allantois ; M, MuUer's canal ; R, rectum ; A, depression corresponding to future anus ; CI, general cloaca ; C, clitoris ; B, bladder ; U, urethra ; V, vagina ; S, sinus uro- genitalis. not descended between the rectum and genito-urinary tract. In arrest of development at a still later stage, both anus and perineum may be found, l)ut the separation of urethra and vagina may occur high up in the pelvis (fig. 85), both organs communicating with the vulva by a single passage. If the clitoris be large (fig. 86), we have here a sort of female hypospadias. Or the developmental narrowing of the urethra may be entirely arrested, and the bladder and vagina may open into the vestibule together (fig. 87). 144 HEEMAPHEODITISM. Lateral deficiencies or redundancies may exist in any part of the vulva, but not so as to allow of their classification in the same manner as those of the vagina or uterus. The most frequent types of malfor- mation are those which give to the external organs of one sex more or less of the appearance of those of the other, giving rise to what is termed Hermaphroditism. By this term was originally meant the union of both sexes — of Hermes and Aphrodite — in one individual. This condition of things was, previous to the opening up of modern gynaecological studies, not unnaturally supposed to exist with moderate frequency. Cases of true hermaphro- ditism — that is, cases where a real testicle, ' capable of secreting spermatozoa, and a real ovary, capable of secreting ova, have been found to exist in the same individual (for this is the only true definition of a bi- sexual human being), are indeed few and far between ; so much so, that a little scepticism may be considered pardonable even as to those which are best authenticated, although no antece- dent impossibility can be pleaded. For an analysis of such cases, and for a most mas- terly discussion of the whole subject, the reader is referred to the second volume of Sir James Simpson's collected works. Personally, I must plead guilty to being still a sceptic. On the other hand, cases where the congenital modifications of the external organs, in shape and relation, are so great as to render it ex- tremely difiicult, if not impossible, to distinguish the sex, are by no means Fig. 88. -Marie Madeleine Lefort, au uudoubted female (after Clim-cliill et Leblond). FALSE HEKMAPHRODITISM. 145 uncommon ; and such a case of false liermaphroditum may at any time occur to the practitioner, when he may be called on, under great diffi- culties, to determine the sex of an infant. Let him not do so off-hand, or without careful consideration, and more than one inspection. All such cases must be recognised as dependent on arrests or redundancies in the development of individual parts, or on incomplete or abnormal union of lateral pai-ts. Thus, a large clitoris, with completely adherent labia, will give a male aspect to a female ; a very small penis, and a scrotum only partly closed in, will give a female appearance to a male. The closure or non-closure of the central raphe is the most frequent source of temporary or permanent mistakes, the complete closure being the male characteristic. The male organs may resem- ble the female in the smallness of the penis, especially if it be hypo- spadic ; and hypospa- dias, if extensive, in- volves to some degree a separation between the lateral halves of the urethra and scro- tum, or even perineum, thus giving rise to an appearance closely re- sembling the vulva. If the testicles have not descended, an arrest in the developmental pro- cess likely enough to be coexistent, we lose another clue to the real sex ; but even if they are apparently present, the possibility of labial hernia of the ovaries must not be forgotten. The female organs will resemble the male when the clitoris and its prepuce are unusually large, and when adhesion has taken place be- tween the opposite labia. Hernial ovaries would make siich a case peculiarly difficult to decide ; and the difficulty would culminate if the rare condition of the urethra, passing along the clitoris and opening at or near its point, also existed. In all difficult cases, a search per rectum for the uterus would solve this doubt, if it were not that absent or unde- veloped uterus may further complicate the matter. Its evident pre- sence is positive, its absence is only negative, evidence of the sex. A very short time may suffice to render more pi-ominent tlie characteristic Fig. -Section of Pelvis of M. M. Lefort (after Churchill et Leblond). o, ovary ; u, uterus. 146 ATEESIA OF THE GENITAL CANAL. sexual organs of the individual ; and at puberty the general physical development, and the form which sexual desire may assume may assist. The former must not, however, be too much depended upon, as the accom- panying illustrations will show (figs. 88, 89). The occurrence of men- strual or seminal discharges, the latter microscopically examined, is of much higher value. If the judgment as to the sex must be suspended, and as its doubtful nature cannot be publicly recognised, it is decidedly advis- able to bring up the child as a male. This will involve less difficulty in after-life, in case of mistake, than will the opposite course. Atresia, or Occlusion of the Genital Canal. So far, I have said little or nothing of the practical inconveniences which accompany any form of malformation that occludes the genital passage at any part of its course. Occlusion of the vulva or vagina will, of course, offer an impediment to marriage, and will, as well as the occlu- sion of the uterus, prevent the escape of the products of menstruation. Closure of the vulva by slight acquired adhesions has already been men- tioned (p. 57), and need not occupy us any further; and such external closure as is due to considerable congenital abnormality of the external organs, as in so-called hermaphroditism, may also be left out of considera- tion. It is either irremediable, or forms part of a still further closure involving the vagina, which may or may not be amenable to treatment. An imperforate hymen is a not uncommon cause of congenital occki- sion, and it generally leads, at an early period of the menstrual life, to a medical investigation. If accumulation of menstrual secretion has taken place above it, it may be found bulging outwards to a considerable extent ; and the same bulging will probably be found when a mere band of vaginal tissue exists just behind the hymen. It rarely bursts, and thus performs a natural cure ; for when the hymen is complete, it is nearly always also hypertrophied. The vagina may, as we have seen, be congenitally occluded in its whole length, being practically absent, or the occlusion may involve any portion of it. Congenital uterine occlu- sion is less common than vaginal, but may involve either the os ex- ternum alone, or the whole or separate portions of the cervix. Various injuries may give rise to narrowing or stenosis of the vagina and uterus, but this is seldom so complete as to lead to absolute occlusion. The same consequences and symptoms will, however, then arise as from congenital occlusion, and the treatment is conducted on the same principles. In congenital atresia of any portion of the tract, the first suspicion of anything being wrong usually occurs at the period of puberty, say from twelve to fifteen years of age. The patient begins to show HiEMATOKOLPOS AND H^MATOMETKA. 147 signs of menstruation, in the form of back-ache and general malaise; and this is generally accompanied by severe colicky pains and some abdominal tenderness, without the least appearance of any external sanguineous discharge. These symptoms subside in a few days, but are repeated with greater severity at more or less regular monthly intervals. They, by and by, begin to be accompanied by a sense of pressure on the bladder and rectum, which never entirely dis- appears. Sometimes there is distinct fever during the monthly paroxysms, leading to a suspicion of, or actually caused by, local inflam- mations. The general health fails, and the patient falls into a state of hectic, with or without anaemia. Medical advice is now sought, if not previously. In some cases the symptoms are not so characteristic. In one, where I had lately to make an artificial vagina, the patient, a girl under twelve years of age, had had no periodic symptoms, but an almost constant agonising colic for nearly eighteen months ; there were no external manifestations of puberty, but an examination of the' abdomen revealed a large globular uterine tumour, easily reached through the rectum. In another case, the symptoms, although present for several years, were so slight, that it was only after marriage that the state of matters was investigated. Sooner or later, if the uterine and ovarian functions continue, the distention caused by their products leads to a tense but fluctuating tumour, the site of which will depend on the seat of obstruction. If the hymen alone, or only the lower part of the vagina be aff'ected, the tumour will, of course, be vaginal (hsemato- kolpos), will press much on the pelvic viscera, leading to constipation and dysuria, and will be felt bulging towards the vulva or almost occlud- ing the rectum. It is only after a considerable time that, the vagina being incapable of further distention, the uterus begins to dilate also, the two cavities being ultimately thrown into one, pretty much as in the second stage of labour. In occlusion of the upper vagina or cervix uteri, the uterine distention alone exists, and gives rise to a smooth globular tumour (fig. 90) in the hypogastrium (hsematometra), often much inclined towards the right side. Great distention of the vagina alone may also be felt above the pubes, and a careful examination may in this case detect the hard undilated uterus at its summit (fig. 91). If the facts and history of the case be strictly inquired into and borne in mind, and a careful examination made, these tumours can hardly be mistaken for pregnancy or ovarian cystic tumour, except in the case of occlusion of the uterus alone, in later life, and from accidental causes. Much of the menstrual fluid in these accumulations is doubtless directly absorbed, or its more liquid parts may exude through the uterine walls under the inevitable pressure, to be then absorbed by the peritoneum ; the remainder constitutes a dark, treacly-looking fluid, of varying density. 148 IMPEKFOEATE HYMEN. and contains altered blood-cells, mucus, and occasionally some choles- terine. As the uterus continues to distend, danger arises, either from its bursting, or from bursting of the Fallopian tubes, which, later, par- take in the dilatation, or from escape of blood into the peritoneum through their fimbriated extremities. There is strong reason also to believe that blood may accumulate in the tubes to a dangerous extent, independently of any reflux from the uterus. It may therefore be laid down as a general rule that, when this condition of dilated uterus or vagina is discovered, the sooner operative measures for its relief are resorted to the better. Unfortunately, the escape of the fluid externally thus induced is apt to be followed by sudden uterine or Fallopian contraction, which may precipitate the accidents just mentioned ; but this danger has to be encountered, and the longer we wait the more imminent it becomes, Fig. 90. — Hsematometra. Uterus distended with blood (Schroeder). Fig. 91. — Hsematokolpos. Vagina distended with blood (Schroeder). especially as the Fallopian tubes are apt to contract adhesions which render this tearing more probable. To the risk which may thus follow the liberation of the retained fluid, there must be added another, viz., the danger of septic changes in what remains, as soon as the external air is admitted. These two classes of danger point somewhat in oppo- site directions as regards treatment, ^ — to avoid the one, the slowest possible exit should be given ; to avoid the other, the sooner the whole can be evacuated and the passages rendered a-septic the better. There is no use in attempting to ignore either horn of the dilemma, in the face of all past experience. Treatment. — Supposing that the hymen alone is the cause of obstruction, there are two modes of treatment open to us. First, we may make a free incision into the obstruction, and dilate it at once with the fingers or with TREATMENT OF GENITAL ATRESIA. 149 a rectum bougie ; then, when free escape has taken place, we wash out the vaginal or utero- vaginal cavity with copious antiseptic injections. These injections must be frequently repeated, and in the intervals the patient must wear as large a size as possible of Sims's or Barnes's dilator. This serves to prevent fresh adhesion, if it does not also to some extent prevent the admission of septic germs. Secondly, we may let off the fluid much more slowly, and with complete antiseptic precautions from the begin- ning. This can sometimes be done by syphon action. A trocar and cannula, the latter furnished with a long india-rubber tube, are inserted through the centre of the hymen ; the tube, first filled with carbolised water, is allowed to hang down into a basin of the same, and the contents of the abnoi'mal cavity thus gradually drain away. When they have ceased to flow, as a momentary lifting of the tube from the basin will ascertain, the cannula is withdrawn, and the orifice in the hymen is closed by a serre-fine or two, or by a suture, or by collodion, if it can be made to adhere. Next day the free incision may be made, and the case treated by antiseptic injections. Very slow aspiration must be substi- tuted for the syphon action if the fluid is too thick to run without it. These two plans should, in my opinion, be used eclectically. If the case is seen early during menstrual life, and when the absence of a supra- pubic tumour renders it probable that there is little or no uterine dis- tention, or distention and adhesion of the Fallopian tubes, the former plan, by free incision, may be used, and in opposite circumstances the latter. In a doubtful case, the latter — by antiseptic drainage — should be preferred. When the fluid will not flow through a moderate-sized cannula without strong aspiration, incision must be proceeded with at once. Small bands of vaginal adhesion, just within the hymen, and felt to be mere membranous obstacles, are to be treated in the same way. More extensive occlusions of the vaginal canal require careful consider- ation before proceeding to their treatment. Their extent must be made out as thoroughly as possible by careful rectal examination, in combination with supra-pubic digital pressure, and also with a sound in the bladder. In this way the presence of the uterus must be distinctly ascertained. We should be quite clear as to the existence of some menstrual molimen, and of some vaginal or uterine distention. It is doubtful how far one would be justified in risking an operation for the mere purpose of holloAv- ing out a vaginal canal, when everything points to the absence of the utero-ovarian structures and functions. The object of the operation is twofold — to make a permanent vagina, sufficient to permit of marriage, and to allow of the immediate and permanent escape of the menstrual discharge. The latter is the primary and more important one, being essential to the life and health of the patient, and it may sometimes be achieved when the former is impossible ; but it must not be attempted 150 OPEEATIOXS FOE THE by apparently easier methods, such as tapping the utenis ;:>er recUira, when a vaginal approach is at all possible. The process of making an artificial vagina, or of opening up any large occluded portion, is simple enough on paper, but not always so simple in execution. The external opening is made with the scalpel. It can only be made large enough by a transverse cut, which must cross at a short distance in front of the anus. If there is a slight vaginal cul-de- sac, it will serve as our guide, and the incision will cross it. The skin or semi-mucous tissue being thoroughly divided in this way, and torsion of any bleeding point having been made, the rest is all done without cutting instruments, except in cases of traumatic occlusion. In these, any very prominent bands of cicatricial adhesion must be divided by slight snipping with blunt-pointed scissors during the progress of dilatation. The patient being anaesthetised and placed in lithotomy position, a catheter is placed in the bladder and held up against the pubes by an assistant. The left forefinger of the operator is introduced into the rectum and retained there as a permanent guide, while the right is used, after the incision is made, as the vaginal dilator. Taking care to re- tain a distinct septum between the advancing finger and the rectum behind and bladder in front, we slowly tear through the connective tissue, work- ing freely from side to side, so as to insure sufficient space, but always pushing onwards. The handle of a scalpel may give a little occasional assistance ; but if so, we must be sm'e that its edges are not too sharp, and that they are only used horizontally. Gradually a passage is thus opened to the uterus, or we open into the dilated upper end of the vagina, and can feel that we are in a cavity filled with fluid. In this case the finger is withdrawn ; and while the treacly fluid is flowing, the largest possible rectum bougie is inserted, until the finger in the rectum shows that it has reached the cavity, when it is withdrawn again. There is not much choice now between slow and quick evacuation. The greatest danger lies in the absorption of the exuding fluid by the raw surfaces thus made, after air has been admitted. A double catheter is passed into the cul-de-sac as far as it will go without force, then very slightly withdrawn, and the cavity is well washed out. More careful search is now made for the os and cervix uteri, which may be either widely dilated or almost normal. The case is then treated on the same principles as when a hymeneal occlusion is concerned ; but very frequent insertion of the vaginal dilator for weeks or months is required to insure complete vaginal patency. It may happen, however, that we may reach the globular uterus, and yet no escape of fluid occur. The uterus itself is occluded. If the situation of the os uteri is apparent, we are advised to pierce it with RELIEF OF VAGINAL ATRESIA. 151 trocar or scalpel. A silver catheter of small size seems to me a more fit- ting instrument. But, as in a case already referred to (p. 1 47), the globular uterus may apparently be there, but no trace of os or cervix to be found. In such a case the surface must be first scraped with the end of a direc- tor, to ascertain that there is no intervening membrane. There was one in the case alluded to, and the finger passed thi'ough into a distinct extra- utei'ine space, the rudiment of the vagina, but still no perceptible os or cervix was to be found. There is no remedy under such circumstances but to make one. This was done, also with the end of the director, and the finger was forced after it. The gush of retained menses followed its removal. The uterus was now washed out, and a male lithotomy tube was inserted into it and retained by tapes, being removed daily, cleaned, and returned. This patient now menstruated freely, although with some dysmenorrhoea ; but I have vainly endeavoured to have her brought to town again for a more careful examination of the state of the parts. If the vaginal canal has been freely opened and the uterus well discovered, and if the symptoms are not urgent, then it would be well to wait some time before proceeding to the treatment of the uterine atresia. This would diminish the risk of septicaemia, and enable us to act slowly, as recommended below. But on no account should the delay be per- mitted if the symptoms of distention are severe, either at the menstrual period or during the intervals. If kept well dilated for some months, the artificial vagina acqiiires a mucous lining, and serves all the purpose of a natural one, even to the extent of enduring the dilatation of child-birth. I can imagine, although I have never seen, a case where the uterine distention may be so great, and the rectal septum so thin, as to make it advisable to perforate -per rectum before attempting the vaginal dissec- tion. Congenital occlusion of the uterus alone is not common, and unless the whole organ is badly developed it is generally confined to the os externum. But acquired occlusion may follow after pregnancy compli- cated with inflammatory sequelae, or after the abuse of strong local appli- cations to, incision of, and other operations upon the cervix. But even long-continued catarrhal inflammation of the cervix may lead to occlu- sion, especially after the menopause, and in such cases it may give rise to little indication of its existence. However the occlusion is produced, if it is during the period of menstrual life, accumulation of inspissated menstrual discharge within the uterus {hri'viatometra) is the result, and the Fallopian tubes are apt to share in this distention (Jucmatosalpynx). The uterine walls may be either hypertrophied or very much thinned. Occlusion may occur after impregnation has taken place ; in which case, owing to the gradual uterine distention, all trace of os or cervix may ■disappear, giving rise to a very awkward c<)m])licati(Mi of labour. It also 152 VAEIOUS EESULTS OF ATEESIA occasionally happens that, menstruation having ceased, the occluded uterus, continues to secrete a quantity of mucous fluid, more or less watery, which distends the organ, giving rise to the same physical signs as hsematometra {hydrometra) ; and in still rarer cases this fluid is or becomes purulent ipyometra), or decomposes, giving rise to the presence of gases {physo- metra). In the diagnosis of all these tumours resulting from occlusion of the uterus, the first important point is to eliminate pregnancy. In con- genital cases this presents little or no difiiculty, except when there is intentional fraud, and untruthful information on the part of the patient. In the case of very old or very young patients there can also be little doubt; but during the child-bearing age, and Avhen the occlusion is not congenital, it may be essential to wait for the evidence afforded by the rate of growth, although a ver^^ careful consideration of the signs of pregnancy {see Appendix) will generally render this unnecessary after the earlier weeks. The non-fluctuating and hard character of solid or malignant uterine or other growths, and of the solidified exudations of pelvic inflammation or hsematocele, should serve to eliminate them, and an examination by the sound will serve to show the non-patency of the uterine canal ; or, if it overcome this, will give exit to the distending fluids. The danger of mistaking an ovarian cyst is in this way avoided. In physometra the clear percussion note over the tumour is very characteristic, although I have met with the same sign in the case of ovarian cysts, when decomposition and gaseous accumulation had taken place. The higher the point of occlusion of the utero-vaginal canal, the more apt are Fallopian complications to occur ; it is therefore important, in un- complicated hsematometra or extensive hydrometra, to promote slow evacuation when possible. If the cervix be present, it must of course be the point of entry ; if not, the speculum may show a depression cone- sponding to the os externum ; failing this, the uterus should be pierced towards its posterior part. In all these cases a long curved trocar and cannula, furnished with an india-rubber tube and allowed to act syphon- wise, as previously directed, should be used. The uterus must not be forcibly compressed, but a comfortable abdominal bandage is permissible. If the stricture be very slight, a catheter may be used instead of the trocar and cannula. Washing out of the uterus vmder these circiimstances is in- advisable, unless sudden rigors or high temperature point to the occur- rence of septic poisoning, in which case a double catheter must be used, to make sure of free egress for the fluid, and the injection must be slow and devoid of force. The opening now made must be kept patent by the frequent passage of a good sized bougie, increasing the size gradually up to No. 1 2 at least. This is preferable to the iise of tents, or of a stem pessary. 01'' THE GENITAL CANAL. 153 In the presence of uterus bicoriiis or other uterine malformations, along with double vagina, cases are recorded of occlusion and vaginal distention on one side only (lateral hsematometra or liEeniatokolpos), and some of double affection (Schroeder, op. cit, p. 59). In the event of double occlu- sion, the symptoms are similar to those met with in the more common or single form ; but the second tiimour, a first having been successfully treated, or the sole tumour when there exists one patent vagina and uterus, must be carefully differentiated from prolapse of the vaginal wall or from vaginal cysts. The former can only be mistaken through want of careful examination and of attempts at reposition ; the latter may re- quire exploratory puncture for diagnosis. Thrombus of the vagina, or pelvic abscess, or heematocele, have each a clear distinguishing history of their own to guide us in diagnosis. The treatment of hsematometra of a rudimentary uterine horn [see Uterus Unicornis) by abdominal inci- sion belongs to the surgery of the, perhaps, not very distant future. For the diagnosis and treatment of mere narrowing, without complete atresia (stenosis) of the cervical canal, the reader is referred to Chapter VIII. 154 OVULATION, CHAPTER VII. Ovulation, Menstruation, and their Disorders. Amenorrhcea. Suppressed Menstruation. Scanty Menstruation. Menorrhagia. Metrorrhagia. Dysmen- orrhcea. Vicarious Menstruation. The Menopause. From a strictly scientific point of view, the consideration of the so-called "functional" disorders of menstruation should be delayed until we have discussed those uterine or ovarian diseases of which they are for the most part mere symptoms and evidences. But there are certain practical advantages to be derived from an opposite course ; and my experience as a lecturer has taught me that it is preferable to speak first of the dis- orders and difiiculties connected with the function of menstruation, taking every care to avoid the serious error of allowing symptoms of disorder — amenorrhcea, dysmenorrhoea, and the like — to be considered as separate diseases, apart from their often numerous causes. The uterus. Fallopian tubes, and ovaries are all more or less concerned in the function of menstruation, and this function is most intimately, although perhaps not inseparably, connected with the function of the ovaries alone — ovulation. Ovulation. By ovulation we understand the production and expulsion of an ovum or ova by the ovaries, there being still every reason to believe that such expulsion obeys, as menstruation does, a very distinct law of periodicity. Within the stroma of the ovary there are found, from the earliest period of extra-uterine life, microscopic appearances, which indicate the presence of enormous numbers of small follicles, the earliest stage of the Graafian vesicles. Henle estimated these as amounting to 70,000 in one ovary which he carefully examined ; and it would appear from the researches of Bischoff, Fowlis, and others, that at birth the ovaries contain nearly all the ova which are to be expelled in after life, although new ones may be formed for a year or two subsequent to birth. As the time of puberty approaches, some of the Graafian vesicles become more apparent, especi- ally near the surface, and finally one of these bursts and discharges its ovum on to the peritoneal surface. At every subsequent monthly ITS NATL'ltE AND PHENOMENA. 155 period this occurs, and at each, the ovum is received iuto the fimbriated trumpet-shaped end of the Fallopian tube, and is so conveyed to the uterus. This is reached after several days, and if no impregnation takes place, the ovum disappears along with the uterine and vaginal secretions. The cicatrix left in the ovary undergoes the changes which give rise to the corpus luteum, true or false, and finally leaves but a faint puckering. The combination of such puckevings during months and years of sexual life gives rise to the altered appearance of the adult ovary as com- pared with that of the adolescent girl (fig. 92). This is the generally recognised course of matters in ovulation, but there is hardly a single point in it which is not considered as still sub juclice by the physiologists ; indeed, it would be well if some of their number, who are not very sparing in their criticisms of the inexactitudes and discrepancies of practical medicine, would furnish us with a little more exact certainty about a function and a phenomenon deserving of their fullest considera- tion. Strong doubts are thrown by some upon the question of periodicity as affecting ovulation. No one can jet tell us beyond dispute whether 1..'=*^' Fig. 92. — Human Ovary. A, from an Adolescent ; B, from an Adult (Young). impregnation affects the recently discharged ovum, or that which follows a month later. The exact process by which the Fallopian tube grasps the ovary, and attracts the ovum to the uterus, is still not clearly defined. All that we can say is, that vascular erection of the fimbriae occurs at the right time, and that capillary attraction towards the uterus seems to aid the action of the cilia of the tubes. The relation in which ovulation and menstruation stand to one another lies also in the debatable land. That ovulation may exist without menstruation is absolutely certain, for pregnancy has often been observed before any sign of menstruation had occurred, and daily happens in women who are not menstruating, owing to the fact of lactation going on. The converse is also true, although its occurrence may be less common. When both ovaries have been removed, menstniation has gone on for several periods with fair regularity. This may, however, and I think with justice, be fairly attributed to the lingering effect of the acquired habit of periodic engorgement, for, as a i-ule, removal of the ovaries involves speedy cessation of all the symptoms. In women who continue to menstruate many years after the apparent 156 DISORDERS OF OVULATION. cessation of coiiceptional power, and who are not the subjects of disease^ we very probably have this habit continued after the generally supposed periodic stimulus of ovulation has ceased. There is reason to believe, also, that in certain cases of sterility, and of dysmenorrhoea, these are due to arrested, or, as Farre termed it, "disappointed ovulation," from thickening of the ovarian coverings. These pathological causes of dis- sociated ovulation and menstruation need, however, in no way invalidate the law that the occurrence and persistence of menstruation are in the first place due to, and mainly kept up by, ovarian stimulation. No ovariotomist has, so far as I am aware, ever discovered a case where a woman who has never menstruated previous to operation, has done so after the removal of both ovaries. When the Fallopian tubes are occluded by adhesions, ovular expulsion is incomplete, and small and repeated attacks of hsematocele are sometimes undoubtedly due to this cause. Extra-uterine foetation is another result of incompleted ovular expulsion. In considering the subject also of dysmenorrhoea (difficult or painful menstruation), we shall not forget to notice that in some instances it is the ovulation, rather than the menstrual phenomena, w4th which we have chiefly to do. It is not necessary here to attempt to trace the role which the ovum or its surrounding vesicle plays in the formation of certain ovarian tumours. After this brief mention of ovulation as a separate function, and of its disorders, I shall take the liberty of considering it, as we are compelled clinically to do, as only a stage in the series of menstrual phenomena. Menstruation. The ordinary features of menstruation are well enough known, but, with regard to its intimate natvire, physiology leaves us nearly as much in the dark as it does with respect to that of ovulation. That the periodic secretion comes from the uterus, at least mainly, is beyond a doubt, but how, or by what changes in the organ it is accompanied, is still a matter open to discussion. The existence of engorgement of the uterus, including its mucous membrane, may be taken as admitted on all hands, as also may the fact that whatever important changes occur in the mucous membrane are confined to the body of the uterus. This membrane becomes swollen and hypertrophied to a considerable extent at each period. At one time the blood oozing from this source was looked upon as a secretion, then (as by Coste) as a transudation without any breach in the capillary tubes, then (as by Farre) as an escape through certain permanent vascular orifices. Pouchet adopted the view that a consider- able depth of the mucous membrane itself is shed. Tyler Smith and MENSTRUATION. 157 Handfield Jones demonstrated that, in many instances at least, almost all trace of the membrane disappeared from the uterine body during menstruation, blood oozing from the subjacent tissues ; and John Williams has so thoroughly worked out and illustrated this view, that 1 believe it is now generally adopted by gynaecologists as a basis for patho- logical views or thei-apeutic action. But there seems to be no finality in such matters. Kundrat has all along maintained, and still maintains, that only the superficial layer is shed, owing to its undergoing fatty degenera- tion. More recently, Leopold, after careful examination in the dead subject, denies the existence of any fatty degeneration, while Moricke, scraping the uterus of living subjects with the curette, leads us back to where we began, and finds that no portion of the mucous membrane dis- appears at all. No wonder that Thomas expresses concerning this discussion what is felt by a good many other gynaecologists, when he says — " I prefer to avoid it." The difficulties of the whole subject, and the absence of any real solution of most of them, are very thoroughly and recently detailed by Leopold (Archiv fur Gynakologie, xxi. 3). Using such slight powers of deciding in the matter as I possess, I am inclined to accept Williams's views {Ohst. Jour., vol. ii.), based on those of Tyler Smith, as being not far from the truth, and as furnish- ing at any rate the best working hypothesis. I accept also in the same way the general principle of ovarian excitation as a stimulant to menstru- ation. The cause of the periodicity of menstruation, or, if it is pre- ferred,' of ovulation, or of the general condition which accompanies these, is to me as yet an unsolved mystery. The periodic menstrual discharge is a phenomenon which is liable to very serious departures from its normal standard, such departures being often due to general, often to local, disease, and, not infrequently, in their turn, the cause of other general or local diseases. Tait has, I think, fairly proved that ovulation undergoes similar irregularities, from which, however, he draws deductions not yet by any means generally received. Departing from my general plan, I think it will be well to add a few more words as to the phenomena observed in health. At every returning monthly period there is an increase in the nervous and vascular tension of the whole system, the former being shown by an increased liability to all forms of explosive nerve disease, and the latter, not only by the feelings of the patient, but by actual sphygmographic tracings of the pulse. Barnes and Fancourt Barnes have shown that this vascular tension begins to rise some three days before the occurrence of discharge, and subsides in about three days from its first flow. Dr Mary Jacobi had previously described the regular sphygmographic wave, and Stephen- son of Aberdeen also publishes some suggestive observations on the sub- ject, although not quite coinciding with Barnes as to the relation of the 158 MENSTEUATION, discliarge to the height of the pulse tension. A striking example of the general tension occurring at the menstrual periods is met with in periodic fulness of the thyroid gland. I have seen one or two instances in young girls where the appearance of exophthalmic goitre was present, but disappeared on the complete commencement of menstruation. The common symptom of swelling and uneasiness of the breasts shows not only this general vascular tension, but also the special sympathy of these organs with the uterus. The pelvic engorgement existing in all cases doubtless corresponds in time with this heightened systemic vascular tension, and the uterus can be felt per vaginam to be heavier and more swollen than usual, while even the cervix is more puffy and patulous. The Fallopian tubes participate in this engorgement, and their extremities cling to the ovary. Lawson Tait states that this occurs at the menstrual period, and that it does not occur during the inter-men- strual period, whether there is a ripe vesicle or not. These functional changes in the tubes are quite sufficient, I think, to show that "they are most markedly under the same periodic influence as that which pro- duces the menstrual flow," but surely not " that they are themselves its cause." The menstrual fluid consists of red blood mixed with varying quan- tities of acid vaginal mucus, and it is the presence of this mucus which prevents coagulation. Coagula are an indication, therefore, of an abnormal amount of sanguineous discharge, beyond what the vaginal mucus can keep fluid, or of some cause of retention of the flow. In most women there is a slight odour special to this discharge, and in some it is, during the whole of life, marked and offensive. I think I have seen this somewhat diminished by the administration of ergotine (Bonjeans's extract, gr. ii. ter die, in pill). This probably acts by pre- venting retention in the uterus, but should not be used without due consideration. In the commencement and at the close of menstrual life, the mucou.s may predominate over the sanguineous element, and in deli- cate young girls, or where menstruation is temporarily in abeyance, or towards the menopause, it may solely represent the flow ; but it must not be confounded with ordinary leucorrhcea. The duration of the flow varies much, say from two to six or seven days, within the limits of health. The quantity also varies much, say from two or three to eight or ten ounces, but this is difficult to ascertain. If, in a woman of cleanly habits, only one or two napkins suffice for twenty-four hours, the quantity is certainly scanty, while if six or more are required it may be considered over-abundant. From thirteen to fifteen is the average age for commencement in this country, but there are great variations here also. Hot climates, luxurious habits, and precocious experiences tend to promote earlier appearance, but it may occur in the absence of any of ITS NORMAL PHENOMENA. 159 these. Exceptionally early menstruation, and even pregnancy as early as from ten to eleven are recorded. Kussmaul mentions a fcase of im- pregnation occurring at eight years. A discharge of blood in very young- infants has not infrequently been met with. I have seen two instances where this occurred slightly two or three times, with fair periodicity, and then disappeared ; and I believe it has occurred persistently ft-om the age of one year. The time of cessation (menopause) varies also within wide limits. Forty-five is usually considered to be about the mean time, but many healthy women cease ten or more years before this, and others continue with perfect regularity till fifty-one or fifty-two. The periodicity of the discharge, while generally observing the law which imposes a lunar month or twenty-eight days, also varies within certain limits. I can vouch for the fact that some women can, for long periods, reckon the recurrence of the discharge by the calendar month and not the lunar, and this where an entry is regularly made in the almanac. It is probably an instance of mental expectancy influencing a physiological function. When the whole period, from the commencement of one dis- charge to the commencement of the next, falls much below the twenty- eight days, morbid conditions are certainly approached, but, in the absence of any deterioration in health, disease cannot be asserted to be present. Attempts have been made to formulate certain types of periodicity, such as the twenty-one day type, but not, I think, with much success. I can only recognise frequent variations, and do not see what is to be gained by collecting a percentage of twenty-seven day cases and calling it a type. We might do the same, equally fruitlessly, with types of gestation. We have already noted the occurrence of a certain amount of systemic disturbance, as shown by nervous and vascular tension, and this must be considered as part of the physiological state ; hence there are few women who are not somewhat unwell, and do not understand the euphemistic term of "being unwell." Some malaise is experienced from distention of the pelvic vessels and of those of the sympathetic mammoe, or of the nerve centres, rendering the woman, for the time, less capable of sustained mental or physical exertion. These symptoms, lassitude, back-ache, irritability, headache, &c., vary much in degree, up to the point of rendering the ordinary duties of life a burden, and requiring temporary but absolute repose of body and mind. Those few women who are entirely exempt from them, and who endeavour by their example to set the fashion to their sex in the way of disregard of such frailties, in educational or other pursuits, may be fitly compared to those men, mostly of a past or passing generation, who are able to impose an eqiially fallacious standard of alcoholic toleration on tlae male sex. There is a stage, although a very indefinable one, at which the severity 160 DISOEDEKS OF MENSTRUATION. of these symptoms, or changes in the character, or amount, or frequency of the discharge, must be held as bringing the case within the domain, and as requiring the title of disease. And here arises a difficulty involving some sacrifice of scientific propriety to clinical necessity. Nearly all the phenomena which we must describe as disorders of menstruation are mere symptoms of something lying behind, of systemic diseases, or of local affections yet unmentioned. The description of a mere symptom as a disease is highly unscientific, yet in no department of medicine can this be entirely avoided. We no longer have separate treatises on the jaundice, or cough, or paralysis, but we still, and that with propriety, may have them on phthisis, or Bright's disease, or diabetes. We treat them to a certain extent as diseases, and speak of their causes and remedies as we must do of those of menstrual disorders, endeavouring, the while, to bear ever in mind that the nearer we can approach to the behind-lying causes of the apparent phenomena, the more scientific and the more successful will our treatment become. Disorders of Menstruation. The menstrual function, or at any rate its ordinary manifestations, may be absent, deficient, excessive, or accompanied by abnormal symp- toms ; and these four natural divisions of the subject may be further subdivided to some useful extent. Thus we must say something about the following — 1. Amenon-hoea, or entirely absent menstruation. 2. Arrested, or suppressed menstruation. .3. Scanty menstruation. 4. Menorrhagia, or excessive menstruation. 5. Metrorrhagia, or irregular uterine haemorrhage. ^ 6. Dysmenorrhcea, or painful or difficult menstruation. 7. Vicarious menstruation. Amenorrhoea. Absence of menstruation, as a symptom of closure of the genital canal, at any point, has already been referred to (Chap. VI.). Under these circumstances the phenomena of periodic vascular and nervous tension, with more or less of the discomfort commonly accompanying them (menstrual molimen), are met with at or about the usual age. These, instead of being followed by the normal discharge, pass away from time 1 This is not necessarily a disorder of menstruation at all, but while treating of menstrual disorders mainly as symptomatic, it is convenient to notice it here. AMENOERHCEA. 161 to time, vuitil they begin to give place to the symptoms of iiitra-pelvic pressure or abdominal pain and distention already described. There is already a presumption in favour of some mechanical obstruction, by the time that the patient is brought for advice. If there is no doubt as to the existence of molimen, there can be no doiibt also of the necessity for some kind of physical examination. At first the abdomen is carefully palpated to see if there is any perceptible tumour. The discovery of this would compel immediate recourse to further and internal examina- tion, no matter how young the patient, but in the absence of any such swelling it is permissible, if the symptoms are not at all urgent, to wait for a short time, and try the effect of treatment such as is recommended when little or no molimen is present. This failing to produce any I'esult, an examination per rectum is to be proposed. By this means we can at once ascertain the presence of any accumulation of menstrual secretion, and can then proceed, if necessaiy, to the further examination by the vagina. The use of anaesthesia is very desirable, permitting as it does, without pain, a thorough bi-manual examination of the pelvis. The occurrence of atresia being established, it must be treated on the lines laid down in the previous chapter. But in the great majority of cases of amenorrhcea, there is no well- defined, if any, molimen, and nothing to lead to the supposition that there is secretion taking place and mechanically retained. The patient has simply arrived at, or passed, the normal age for menstruation, and for that reason alone, or because she is out of health, a fact always attri- buted by the patient's friends to the amenorrhcea, she is brought for advice. Here an examination must be the exception instead of the rule. If marriage is contemplated, or if the patient is old enough to have acquired the right to ask for accurate information, then it is of course demanded, but otherwise, it must be borne in mind that the cause of such retarded flow is usually constitutional, and that no young girl should, while this is still probable, be subjected to an examination of the kind re- quired for a complete diagnosis. If, by means of examination, we detect a complete atresia, but without distinct molimen, and with no sign of retention, I have already strongly coimselled non-intcrfercncc. Nothing but an approaching marriage and the determination to proceed with it, after all has been explained, would justify the attempt to make a vagina in the absence of all evidence of uterine or ovarian functional existence ; I should personally object very strongly to operate even under these circum- stances. But in complete amcnoiThoea, examination may detect, not atresia, but imperfect development of the uterus, — the infantile uterus, to be afterwards described (Chap. VIII.), — with its usual accompani- ment of undeveloped ovaries. In such a case, also, I would advise that nothing should be done, surgically at least. Menstruation, if established 162 TEEATMENT OF AMENOEEHGEA. under such circumstances, will be fitful, painful, and productive of far more mischief than amenorrhoea. If, however, after a time, nature attempts to carry on the function, and that fitfully, painfully, and scantily, we shall be justified in using such means to assist in the pro- cess as are described when speaking of the infantile uterus or of dys- menorrhoea. In the absence of an examination, or in the event of our finding no mechanical obstruction, or the absence, or rudimentary condi- tion of organs, constitutional treatment must be tried, and will nearly always succeed. The utmost endeavour must be made to promote the mens sana in corpore sano. Early hours, nutritive food, a full but not excessive amount of sleep, thoroughly ventilated homes, or workshops, or school-rooms, avoidance of over-work or over-education, out-door exercise in some form, warm woollen under-clothing and hosiery, daily bathing in water as cold as can be comfortably borne, and when this is followed by good reaction, careful attention to the bowels, without purgation if pos- sible — these, combined with the judicious use of cod-liver oil, iron, man- ganese, arsenic, strychnine, or quinine, constitute the true promoters of menstruation, or emmenagogues, in simple amenorrhoea. It is well when mothers can be persuaded to avail themselves of these alone in the case of their young daughters. There are certain drugs which have the repu- tation of a specific action on the menstrual secretion, but I prefer to re- serve the mention of these imtil we speak of their more fitting sphere of action in arrested or deficient menstruation. The departures from general health which most frequently account for late or absent menstruation will also be more fully mentioned there. The appearance of molimen must be watched for, and its advent shoiild be the signal for the use of a warm or even hot hip bath, or of an injection of warm water into the rectum at bed-time, for a few days, or until the flow appears. Arrested Menstruation {Supjjressio Mensium). Here the flow has been established to some extent, or for a consider- able time, but its regular occurrence is interrupted, and that some- times suddenly, at other times gradually, from some cause, often obscure, sometimes apparent enough. These causes may be classified as follows : — 1. Constitutional delicacy. 2. Diseases of, or leading to, mal-nutrition — phthisis, Bright's disease, prevent adhesion of the cut surface, the tip of the finger, well carbolised and lubricated, should be passed as far as possible into the wound, every second day for a week or more, and a sound should be passed intf) the uterus once or twice previous to the next period. What are the comparative merits of dilatation or incision ? F refer, of course, only to their bearing on cervical narrowing Avith d^'smen- orrhoea. Dilatation I believe to be safer, if conducted with the jire- cautions mentioned above. Only in comparatively rare cases, and to the skilful specialist, would I recommend incision of the os internum. I would therefore advise the use of dilatation first, in most cases where 190 OOPHOEECTOMY IN DYSMENOREHCEA. one of the two courses is indicated. But dilatation is in some cases more painful, more tedious, and more liable to failure by relapse. When therefore dilatation by sound is unusually painful or diflficult, when the effect of one sitting is more than once not apparent at the next, or when the relief obtained by dilatation at one menstrual period is totally lost at the next, I would recommend that incision should be used. The circumstances of patients, especially those in hospitals, must always form an element in such calculations ; a patient with abundant leisure and a comfortable home may often, regret it as we may, be treated in a different manner from one who must choose between a flying visit to a dispensary in the midst of work, or a stay of two or three weeks in the wards. The physician must weigh these points, the patient cannot. However the cervix may have been mechanically enlarged, it should occasionally be explored with a full-sized bougie for some months, or, if the uterus is evidently not very irritable, a glass intra-uterine pessary (fig. 99) may be worn in the interval between the periods. It is very difficult to convey to the reader the fre- quency or infrequency with which such processes are required. The student is too apt to leave college with the idea that ovariotomy, amputation at the hip joint, removal of the tongue or larynx, and the like opera- tions will frequently come across his path to do or to recommend, though he speedily undergoes dis- illusion. To such I would say, dysmenorrhcea is a symptom, a very common symptom, of constitutional states or common female affections. Constriction of the cervix is only one among many, but it is one ; you must therefore avoid the common error of considering it as almost the sole cause, and you must equally be prepared to treat it surgically when you can clearly diagnose its existence. 4. Removal of the Ovaries and Fallopian Tubes. — Eemoval of the ovaries, with or without the Fallopian tubes, is now freely recommended for certain forms of dysmenorrhcea, since Battey brought the opera- tion into prominent notice in 1872. The consideration of oophorectomy, normal ovariotomy, spaying, or whatever the disputants may finally choose to term it, will be best undertaken when the ovary itself is under consideration. Here I need only say that the result of the cases I have seen, or of the many of which I have heard and read, has been to convince me that, for nervous affections, hysteria, epilepsy, hystero-epilepsy, &c., supposed to depend on ovarian or men- strual derangement, it is at best a very doubtful remedy and one involv- FiG. 99.— Glass In- tra-Uterine Stem Pessary. VICAEIOUS MENSTEUATION. 191 ing a grave responsibility which I should rarely be prepared to undertake. On the other hand, in the presence of continued dysmenorrhoeal pain, with undeveloped sexual organs, or with distinct evidence of ovarian or Fallopian induration, enlargements, or displacements, which had resisted the known methods of treatment, I dare not refuse to a woman the relief from suffering which is clearly held out by many successful cases of i-emoval of the uterine appendages under these circumstances. The treatment of metrorrhagia as a symptom of certain local uterine organic diseases, and apart from any special relation to menstruation, will be further referred to under the headings of Uterine Tumours, Cancer, &c. Vicarious Menstruation. Instances of complete vicarious menstruation — that is, of continu- ously periodic discharges of blood from other parts of the body than the uteinis, and entirely replacing the normal discharge — are very rare, mere lusus naturae. Yet they have been sufficiently often recorded to show that nature does thus sometimes relieve its periodic vascular tension through other channels, chiefly through mucous surfaces. Less clearly marked cases of haemoptysis, ha;matemesis, epistaxis, and the like, independent of ascertainable disease of the organs from which they proceed, and accompanying scanty or absent uxenstruation, are not uncommon. The difficidty lies in determining when such hsemorrhages are in any sense vicarious, and when not. In spite of the known general systemic tension at the menstrual periods, it is difficult to avoid the suspicion that there must be some local weak- ness which determines the source of haemorrhage. A sound practical rule is, that whenever a case of supposed vicarious menstruation has been met with, it is wise not to lose sight of the organ from which it pi'oceeded for a considerable time. In the temporary absence of physical signs of disease of that organ the most skilful practitioner may be mis- led, without this precaution. When menstruation in the natural way can be safely promoted, it forms the proper treatment of such a case, and I am not aware that anything more can be said on the matter. After having taken so much pains to impi-ess upon the student the necessity of regarding menstrual disorders as merely symptomatic, 1 should perhaps apologise for devoting so much relative space to their discussion. The only excuse is this, that he who, in a large general l)ractice, ftiithfully studies the causation of these symptoms, and so treats them rationally, will relieve far more human suffering than the most distinguished operator or discoverer can do, apart from his influence <)i\ the practice of others. 192 THE MENOPAUSE. The literature of the physiology of meustiiiation is so scattered, that I cannot refer the English student to any better introduction to it than Williams's ]Daper in the Obstetrical Journal, vol. ii. Its disorders are also discussed in every test-book, but can only be fully studied by one who will take the trouble to consult the various medical periodicals of the last decade. The Menopause. Towards the close of menstrual life — the menopause — the female sys- tem becomes liable, as at its commencement, to many functional dis- orders ; and, as this is also the most frequent period of origin of many organic diseases, especially of cancer, it is very important that they should be known and recog-nised. Cessation may be sudden or gradual, or with several intermittent threatenings. It may be absolutely with- out general symptoms, or it may give rise to many. The key to most of them lies in abnoimal disturbances of circulation and innervation. Painful and otherwise causeless flushings of the head and face, often accompanied by headache, giddiness, or disorders of the special senses, are most frequent. Attacks of menonliagia often occur, but nothing- can be more dangerous to the patient or to the reputation of the practi- tioner than to adopt without examination the popular formula of '' change of life " as their cause. I am afraid to guess how many cases of polypus I have seen allowed to bleed the patient almost to death from such inadvertence. Every form of neurasthenia, neuralgia, hysteria, convulsive disease, melancholia, or other mental affections, is rife at this time. Dyspepsia is constantly met with in its protean forms. Vicarious hsemoiThage is now, if ever, a reality ; and that odd mimetic affection, spurious pregnancy, has to be suspected. While there is a tendency for non-malignant growths, especially uterine fibroids, to become stationary or to be absorbed, there is an opposite tendency in all forms of malignant disease. The woman who has arrived at this period should be as carefully guarded against noxious influences as the young adolescent girl. Her diet and regimen should be carefully attended to, the too free use of alcohol especially being forbidden. Gout, or the tendency to lithiasis, are apt to develop themselves, and must be giiarded against. The bowels must be regularly attended to, and in most cases occasional free purgation is acknowledged by the patient to relieve her symptoms. The uterine haemorrhages, so frequent in some degi-ee, must be carefully diff"erentiated from those of organic disease, and are best controlled by the free use of ergot. The various nervous s^onptoms demand cai-eful regulation of the occupations and amusements of the sufferer, and kindly THE MENOPAUSE. 193 care at this time is the surest j)relude to a green, prolonged, and viseful old age. Too many a woman of forty-five to fifty years of age has her futui-e usefulness and happiness destroyed by sacrificing herself at this time to the whims and exigencies of her growing family ; and society loses incalculably' in all its social and philanthropic aspects when it loses the services of a hale, experienced woman, who has passed safely through the climacteric period. I have little or nothing to say in the way of dnig treatment of this period, further than that the bromides as a non-narcotic sedative, aperients as a species of derivative or temporary substitute for other evacuations, and ergot as a controller of haemorrhage, have now their special value, while the various tonics — iron, strychnia, quinine,