COLUMBIA LIBRARIES OFFSITE HEALTH SCIENCES STANDARD HX641 07280 R488.M221915 The RECAP wtfoeCftpoUfotogork QfriUwj* nf pjjjHtriattH anil ^urgwma L v_-/ JTV : br&.& CANE JBLISHER Y-NINE STREET Y College of Physicians and Surgeons roXinehts„„of J fisher*. Digitized by the Internet Archive in 2010 with funding from Open Knowledge Commons http://www.archive.org/details/goldheadedcaneOOmacm THE GOLD-HEADED CANE. THE GOLD-HEADED CANE BY WILLIAM MACMICHAEL'M'D' WITH AN INTRODUCTION BY SIR WILLIAM OSLER, B. A., M. D., F. R. S. AND A PREFACE BY FRANCIS R. PACKARD, M.D. NEW YORK PAUL'B'HOEBER 1915 . Copyright, 1915 By PAUL B. HOEBER Published April, 1916 Printed in the U. S. A. INTRODUCTION. It is very fitting that a new edition of the Gold Headed Cane should appear just at this time, as a memorial of the life and labours of its first owner, Dr. John Radcliffe. Here in Oxford, where his name is writ large in stone, we had hoped to have ceremonies appropriate to the 200th anniversary of his death, but at present the University has other things to think of. The Radcliffe Trustees have, however, ar- ranged with Dr. Nias and the Clarendon Press to issue a brief life and an account of- the Trav- elling Fellows, with whom his name is associ- ated. When and where he got the celebrated cane is unknown. To the story of his life so well told here by Dr. Macmichael nothing need be added. There is probably no name in our profession with which are associated so many benefactions. The Radcliffe Infirmary, orig- inally erected by his Trustees out of their funds, has become one of the most important vi INTRODUCTION. of the county hospitals in England; but the Trustees no longer have any financial interest in its support. The Radcliffe Observatory was built by them and they pay the upkeep and the salary of the Radcliffe Observer. The Radcliffe Camera or Library, one of the most beautiful buildings in Oxford, was designed for the scientific part of the Bodleian Library. After the laboratories were centred about the museum it was found more convenient to have the scientific books close at hand, and one of the old Guilds, the Draper's Company of Lon- don, put up a beautiful new building in which the Radcliffe Library is now housed, all the expenses of which are paid by the Trustees. Also under Dr. Radcliffe's will £600 a year is paid to St. Bartholomew's Hospital. The property is largely in land not far from Stony Stratford. In addition, he left his Yorkshire estate to the Master and Fellows of University College, to provide for the maintenance of the Travelling Fellows: one is elected each year and holds the appointment, worth <£200, for INTRODUCTION. vii three years, one of the conditions being that he spends half of the time in studying abroad. These splendid benefactions keep alive the name of Dr. RadclifFe in Oxford and in profes- sional circles. In many ways the account of Mead is the best in the volume. Of him Johnson is re- ported to have said that he lived more in the sunshine of life than any man he knew. Dr. Macmichael in this little volume has done more for Mead's memory than his published works. It is a pity that he did not hand over his won- derful collections to the College of Physicians. Now the bibliophile turns the pages of the printed catalogue of his books, which took twenty-seven days to sell, and mourns that the treasures of his lifetime should have been dis- persed. About the next possessor of the Cane, An-^ thony Askew, the memory lingers in connec- tion with the famous Bibliotheca Askeviana, the priceless treasures of which were dispersed in 1775 in a twenty days' sale. Only one of viii INTRODUCTION. the great libraries collected by physicians in the 18th century remains. William Hunter had the good sense to leave his books, coins, manu- scripts and specimens to his native place, and the Hunterian Library and Museum are among the most precious possessions of Glas- gow University. Pitcairn is remembered to-day solely from his association with the Cane. In the rambling section under his name, Macmichael does not tell us much about him, and leaves us a little in doubt when he died, and whether or not his nephew, David, was one of the possessors of the Cane. As a practitioner he appears to have picked up the secret of Sydenham's suc- cess, the free use of opium, as in the book he speaks of his currus triumphalis opii. Baillie, in many ways the most distinguished possessor of the Cane, had caught the inspira- tion from his uncles John and William Hunter, and to him more than to any other man is due that close combination of pathology with clinical medicine, still the distinguishing INTRODUCTION. ix feature of the English school, and of which such splendid use was made by Bright, Addi- son, and Hodgkin. Few books of its kind have been more suc- cessful, and that a new edition should appear from the press of Mr. Hoeber is an indication of the zeal with which the study of the history of medicine has been taken up by the profes- sion of the United States. Oxford, February 26th, 1915. PREFACE William Macmichael, the author of the Gold-Headed Cane, was born at Bridgenorth, in Shropshire, in 1784, and after receiving his education at the grammar school of that town, entered as a student at Christ Church, Oxford, where, after receiving his degree of Master of Arts in 1807, he graduated as a Doctor of Medicine in 1816. In 1811, he was elected to the Radcliffe Travelling Fellowship which owed its foundation to the generosity of Dr. Radcliffe, about whom he writes so delight- fully in his chef d'ceuvre. These fellowships were founded with the purpose of giving their holders the opportunity of travel in foreign lands, and Dr. Macmichael passed several years journeying in Russia, Turkey, Greece and Palestine. That he was an observing and interested traveller is manifested in a little work which he published in London in 1819, entitled " A Journey from Moscow to Con- stantinople, in the Years 1817 and 1818." He was, for a short time, physician to Lord xii PREFACE. Londonderry while the latter was ambassador to Vienna. He settled in London in the prac- tice of medicine in 1818, and was elected a fel- low of the College of Physicians of London in the same year. At the outset of his career as a practicing physician, he had the good fortune to secure the friendship of Sir Henry Half ord, to whom the College was indebted for the gift of the Gold-Headed Cane, which had de- scended to Sir Henry from the distinguished line of bearers about whom Macmichael cen- tered its autobiography. Sir Henry Half ord's influence in professional and social circles in London was immense. His name was really Henry Vaughan. His father was a physician in Leicester, who devoted his entire income to the education of his seven sons, all of whom proved themselves worthy of the parental self- denial by the eminent positions which they sub- sequently obtained in the professions which they respectively adopted. Sir Henry, after graduating from Oxford, secured an advan- tageous social position for himself by his mar- riage to the daughter of Lord St. John of Bletsoe. He inherited a large property on the death of Lady Denbigh, the widow of his PREFACE. xiii mother's cousin, Sir Charles Halford, Bart., and by an act of Parliament, in 1809, changed his name from Vaughan to Halford. In the subsequent year he was made a baronet. He attended in a professional capacity George III, George IV and Queen Victoria, and after the death of Matthew Baillie, he had the larg- est and most fashionable practice in London. Halford was the president of the College of Physicians of London from 1820 until his death in 1844, and it was during his presidency that the College was removed from Warwick Lane to Pall Mall East. Those who envied his position attributed his success to his courtly manners, and he was nicknamed " the eel- backed baronet." The story is told that he galloped from the death bed of George IV out to Bushy Park in order that he might have the honor of being the first to inform William IV of the glad event. He was present at the opening of the coffin of Charles I, in 1813, and published an account of the proceedings on that occasion. J. F. Clarke, in his autobiog- raphy, accuses Halford, amongst other things, of retaining possession of part of the King's fourth cervical vertebra through which the xiv PREFACE. axe passed, and displaying it at his dinner table as an interesting curio. Halford, in the words of Dr. Munk, " at the height of his success, and when his duties at Court were the most onerous, found it neces- sary to have in reserve some physician on whom he could implicitly rely, to act as his representative and substitute when such was needed. His choice fell on Dr. Macmichael, who, through Sir Henry's influence, was ap- pointed in rapid succession Physician Extraor- dinary to the King in 1829, Librarian to the King in 1830, in place of a very eminent physician, Dr. Gooch, recently deceased; and finally, in 1831, Physician in Ordinary to the King?' Halford had been obliged to resign his po- sition as physician to the Middlesex Hospital, owing to the pressure of other duties, as early as 1800; but it was probably due to his influ- ence that twenty-two years later Macmichael was appointed to the same position. Mac- michael was very active in the affairs of the College of Physicians, served among its offi- cers on several occasions, and read a number of communications before it. He wrote vari- PREFACE. xv ous articles on contagion and infection, none of them possessing any great value. In spite of powerful backing and the important posi- tions he held, Dr. Macmichael lacked the am- bition or did not possess the aptitude to acquire a large practice. In 1830 Macmichael published " Lives of British Physicians," of which another edition was published by Thomas Tegg in 1846. Macmichael himself contributed to it the lives of Linacre, Caius, Harvey, Sir Thomas Browne, Sydenham and Radcliffe. The biog- raphies of twelve other English medical wor- thies were contributed by Dr. Bisset Hawkins, Dr. Parry, Dr. Southey, Dr. Munk, and Mr. Clarke. The book is a small volume contain- ing portraits of some of the more famous subjects. It was dedicated to Sir Henry Halford. Although not so happy in its con- ception and execution as the Gold-Headed Cane, this little work is a most valuable con- tribution to English medical literature. The lives are well written, accurate, and contain information much of which is derived from sources inaccessible to the general reader. In 1837, at the age of fifty-three, Dr. Mac- xvi PREFACE. michael suffered a stroke of paralysis which obliged him to retire from professional life and he died two years later at his residence in Maida Vale. Sir Thomas Watson, the fa- mous London Physician, was one of Dr. Mac- michael's friends who knew him many years. In 1878 Sir Thomas Watson wrote of him as follows, to Munk: 1 "Dr. Macmichael was fond of society, and qualified alike to enjoy and embellish it. Having travelled long and seen many cities and the manners of many men, he possessed a large stock of general information, was fertile in various and amusing anecdotes, and was wont to mix, with certain natural ease and grace, in lively and interesting discourse, without making his own share in it unduly prominent. His cheerfulness and equanimity of temper, and kindness of heart, endeared him to a large circle of devoted friends, of whom a very few only, at the time of this writing, survive to commemorate his engaging qualities and to regret his loss." Under Sir Henry Halford's presidency the College of Physicians underwent a great 1 Roll call of the Royal College of Physicians, article on Macmichael. PREFACE. xvii awakening. It acquired, largely through his individual efforts, a splendid new home and he also originated the evening meetings which were henceforth held in the Hall. These were held once a month during the first six months of the year, at nine o'clock in the evening. Tea and coffee were provided. The meetings were attended not only by physicians, but by many persons of prominence in the various walks of life. The papers presented at them were, therefore, as a general rule, adapted to a mixed audience. They were not read by their authors, but by the Registrar of the Col- lege, except in the instance of the President, who was permitted to read such communica- tions as he might wish to make himself. A great part of Sir Henry Halford's success in these innovations was due to the active part taken by Macmichael in seconding his efforts in this as in every other way by which he could show his gratitude and aid his friend and bene- factor. In nothing could he have succeeded better in awakening renewed interest in the venerable College than by directing attention to its past history and to the achievements of the illustrious men who had been connected xviii PREFACE. with it. It was probably this desire which led Macmichael to utilize his erudite knowledge of the subject in the compilation of the fasci- nating book to which he gave the name of " The Gold-Headed Cane." The new College was opened on the 25th of June, 1825. According to its veracious auto- biography, on the previous day the Cane was deposited in a corner closet of the new build- ing, " with the observation that I was no longer to be carried about." The Gold- Headed Cane now occupies a glass case in the Library of the College, where it may have the consolation of feeling that it is gazed on by many visitors who have read its history and been stimulated by it to wish a close view of the author. The Cane was carried successively by Rad- clifTe, Mead, Askew, Pit cairn and Baillie, and bears their various arms engraved upon its head. It was presented to Sir Henry Hal- ford by Dr. Baillie's widow and he in turn placed it in the College. Dr. Macmichael's happy inspiration to write its autobiography was carried into erf ect at the time when the enthusiasm of the Fellows at PREFACE. xix the acquisition of their splendid new hall was at its height. The first edition was published in 1827, and a second edition in the succeeding year. A third edition, edited by Dr. William Munk, was published in 1884, forty-five years after Macmichael's death. The cane in ancient days was regarded as an essential part of the equipment of every physi- cian. Dr. Munk, in the third edition of the Gold-Headed Cane, adverts to this fact and also explains the origin of the custom. The cane usually carried by physicians had for its head a knob of gold, silver or ivory, which was hollow, and perforated so that it served to con- tain aromatic preparations which could be in- haled as a preventive of contagion. The favorite preparation for this purpose was the " vinegar of the four thieves," or Marseilles Vinegar, an aromatic vinegar which, according to the confession of four thieves (who had, during a plague at Marseilles plundered the dead bodies) had prevented them from con- tracting* the disease while pursuing their ne- farious occupation. The Gold-Headed Cane was adorned by a cross bar for a top instead of a knob, a fact xx PREFACE. which Munk explains by the statement that Radcliffe, its first owner, was a rule unto him- self, and very possibly preferred a handle of that kind for his cane as a distinction from that used by the majority of physicians. With its passage from the possession of Dr. Pitcairn into that of Dr. Baillie, the Cane pa- thetically states: "I ceased to be considered any longer as a necessary appendage of the profession, and consequently the opportunities I enjoyed of seeing the world, or even of knowing much about the state of physic, were very greatly abridged, and of but rare occur- rence." With the account of Baillie and the state of physic in his time the Cane ceased its autobiog- raphy and regarded its honorable career as closed. Dr. Munk, in the third edition, pub- lished in 1884, wrote a continuation of the nar- rative in very good imitation of Macmichael's style, which brought the story down to the year 1871. The publication of a new edition of a medi- cal and literary classic such as the Gold- Headed Cane requires no apologia. The three previous editions are now all of them PREFACE. xxi so difficult to obtain, the book so eagerly- sought for, and its perusal productive of so much profit and pleasure, that the demand is obvious. The medical profession in Great Britain and America owe the present undertaking entirely to the unselfish zeal of the Publisher, whose love and admiration for the merits of the Cane prompted him to undertake a venture from which in a commercial point of view no profit can be expected. The present edition follows the text and illustrations contained in the second edition, which was chosen for reprinting because it was revised, added to and published by the author himself. The first edition contained 179 pages. To the second edition Dr. Mac- michael added 88 pages of text, which con- tain much of the very best of his work. The third edition contained no illustrations, and al- though the continuation of the narrative is most interesting, it is not Macmichael's and therefore not the Cane's. It is to be hoped that with the recent great stimulation of interest in medical history which the profession in this country has shown this xxii PREFACE. little volume will achieve the same popularity as its predecessors and add more lustre to the glory of the Cane. Francis R. Packard. Philadelphia, March, 1915. BIBLIOGRAPHY OF THE WRITINGS OF WILLIAM MACMICHAEL. " A Journey from Moscow to Constantinople in the year 1817-18." 4to, London, 1819. "A New View of the Infection of Scarlet Fever; illus- trated by Remarks on Other Contagious Disorders," 8vo, vi, 100 pp. London, T. and G. Underwood, 1822. " A Brief Sketch of the Progress of Opinion upon the Subject of Contagion, with Some Remarks on Quar- antine." 8vo, London, 1825. " The Gold-Headed Cane," 179 pp., 8vo, London, J. Murray, 1827. " The Gold-Headed Cane," 267 pp., 8vo, London, J. Murray, 1828. " Is the Cholera Spasmodica of India a Contagious Dis- ease ? " The question considered in a letter to Sir Henry Halford, Bart., M.D. 34 pp., 8vo, London, J. Murray, 1831. A French translation of this pam- phlet was published in Paris in 1831. " Some Remarks on Dropsy; with a Narrative of the Last Illness of H. R. H. the Duke of York " ; read at xxiv BIBLIOGRAPHY. the Royal College of Physicians, May 25, 1835. 18 pp., 8vo, London, J. Murray, 1835. "The Gold-Headed Cane," edited by William Munk, XVI, 266 pp., 8vo, London, Longmans, 1884. In this edition the editor continues the narrative of the Gold-Headed Cane down to the year 1876, in imi- tation of Macmichael's style. It lacks the quaint il- lustrations which ornamented the first two editions and added so much to their charm. THE GOLD-HEADED CANE. SECOND EDITION. LONDON: JOHN MURRAY, ALBEMARLE-STREET. MDCCCXXVIIT. TO THE HONOURABLE LADY HALFORD, THIS VOLUME IS DEDICATED WITH SENTIMENTS OF THE GREATEST RESPECT AND ESTEEM^ BY HEE LADYSHIP'S MOST FAITHFUL SERVANT, THE EDITOR. NOTICE BY THE EDITOR. A short time before the opening of the New College of Physicians, Mrs. Baillie presented to that learned body a Gold-Headed Cane, which had been successively carried by Drs. Radcliffe, Mead, Askew, Pitcairn, and her own lamented husband. The arms of these celebrated Physicians are engraved on the head of the Cane, and they form the Vignettes of the five Chapters into which this little Volume is divided. CONTENTS PAGE CHAP. I. RADCLIFFE 1 CHAP. II. MEAD . . . . . . .51 CHAP. III. ASKEW 149 CHAP. IV. PITCAIRN 174 CHAP. Y. BAILLIE 225 RADCLIFFE. CHAPTER I. When I was deposited in a corner closet of the Library, on the 24th of June, 1825, the day before the opening of the New College of Physicians, with the observation that I was no longer to be carried about, but to be kept amongst the reliques of that learned body, it was impossible to avoid secretly lamenting the obscurity which was henceforth to be my lot. Formerly the entree of palaces had been open to me; I had been freely admitted into the 2 RADCLIFFE. houses of the great and the rich; but now I was doomed to darkness, and condemned to occupy the corner of a library — spacious and splendid, it must be allowed, but where I was surrounded by nothing but the musty manu- scripts of defunct doctors. The gloom, how- ever, of my present abode was enlivened on the following day by my overhearing the ele- gant oration of the President of the College; and an occasional glance I had of scarlet dresses recalled the decorum and propriety of the days of yore, when, on all solemn occasions of public meeting, the Fellows appeared hab- ited in the doctors' robes of their respective universities. I had passed through so many erudite hands, and had been present at so many grave consultations, that the language of the oration was familiar to me, and I could easily collect, from certain allusions in the speech, that princes of the blood, the legislators of the land, the nobles and learned of England, formed a considerable portion of the audience. The topics upon which the accomplished orator touched were various and interesting; but I listened with increased attention when I heard him speak of the donation of the Radcliffe RADCLIFFE. 3 Trustees *, and every fibre thrilled within me at the consciousness of the heartfelt delight with which my first kind and generous master would have grasped me, could he have fore- seen the liberal spirit of the future guardians of his princely fortune. The low murmur of applause which accom- panied the commemoration of the integrity and honest simplicity of character of the last physician, whose hand I had graced, checked as it was by the reflection, that he was now, alas! no more, marked alike the eloquence of the orator, and the good taste and feeling of his audience. But the speech was too soon finished, and the guests slowly retired from the Library. I was once more left to silence and solitude; never, perhaps, to see the light of day, unless when my closet was occasionally unlocked, that I might be shown as a curiosity to some idle and casual visitor. I had, how- ever, been closely connected with medicine for a century and a half; and might consequently, without vanity, look upon myself as the de- positary of many important secrets, in which * £2000 towards the building of the New College of Physicians. 4 RADCLIFFE. the dignity of the profession was nearly con- cerned. I resolved, therefore, to employ my leisure in recording the most striking scenes I had witnessed. The Doctors had indeed re- sumed their robes; but it was too much to expect that they would again carry the cane, and adopt the use of the full-bottomed wig; though I have not the least doubt that the honour of physic, and perhaps the welfare of mankind, would be greatly promoted by so praiseworthy a practice. These Memoirs are the fruit of my retire- ment; and should the reader feel any disposi- tion to authenticate my narrative by reference to the records of the different periods it em- braces, I feel no fear for the result of his in- vestigation: since if the written documents be correct, they must agree with my story. Of my early state and separate condition I have no recollection whatever; and it may reasonably enough be supposed, that it was not till after the acquisition of my head that I became conscious of existence, and capable of observation. But I shall never forget the first consultation at which I was present; where every thing being strange to me, I was RADCLIFFE. 5 attentive to the most minute circumstances, which then came recommended to my notice as well by the importance and dignity of the patient, as by the novelty of the scene. As in these conferences there is usually much mat- ter of routine, I became afterwards more care- less; and as none of the responsibility of the advice given rested with me, I allowed my thoughts to wander. It was in the autumn of 1689. My master, Dr. Radcliffe, had just then returned from a distant journey in the country, and was much fatigued, when an urgent message reached him at his house in Bow-street, Covent Gar- den. Snatching me up, he hurried into his carriage, and set off with all speed- for Ken- sington House. This irregular edifice, which had recently been purchased by the crown of the second Earl of Nottingham, had under- gone several alterations, and received some additions hastily put together for the imme- diate accommodation of the court. The edi- fice itself was not extensive, having rather the appearance of the neat villa of a nobleman than that of a royal mansion; and the gar- dens were upon a small scale, but kept in the 6 RADCLIFFE. neatest possible order. From the town of Kensington, the approach was by a double row of large elm trees, leading to the north entrance of the house, through an unenclosed field, which was at that time disfigured by a gravel-pit. Here, however, afterwards, the skill of the famous gardeners of the day, London and Wise, was employed; and the cut yew and variegated holly hedges were taught to imitate the lines, angles, bastions, scarps, and counterscarps, of a regular forti- fication. This curious upper garden, known by the name of the Siege of Troy, was long the admiration of every lover of that kind of trim horticultural embellishment *. We were ushered through a suite of several rooms, plainly but handsomely furnished, by Simon de Brienne; and it seemed to me that the Doctor assumed a more lofty air, and walked with a firmer step, and I was con- scious of a gentle pressure of his hand, as he stopped and gazed for a moment on the like- ness of the Founder of the College of Physi- * All this has now disappeared ; the ground being en- closed about forty years ago, and converted into pasture land. RADCLIFFE. 7 cians, Dr. Linacre, painted by Holbein, which was hanging in one of the rooms, amongst the royal portraits of the Henrys, and several other of the Kings and Queens of England and Scotland. On entering the sick chamber, which was a small cabinet in the south-east angle of the building, called the Writing Closet, a person of a grave and solemn aspect, apparently about forty years of age, of a thin and weak body, brown hair, and of middle stature, was seen sitting in an arm-chair, and breathing with great difficulty. The naturally serious char- acter of the King (for it was His Majesty William the Third) was rendered more melan- choly by the distressing symptoms of an asthma, the consequence of the dregs of the small-pox, that had fallen on his lungs. In the absence of the fit, and at other times, his sparkling eyes, large and elevated forehead, and aquiline nose, gave a dignity to his coun- tenance, which, though usually grave and phlegmatic, was said in the day of battle to be susceptible of the most animated expres- sion. " Doctor," said the King, " Bentinck * * Earl of Portland. 8 RADCLIFFE. and Zulestein * have been urgent with me that I should again send for you; and though I have great confidence in my two body-physi- cians here, yet I have heard so much of your great skill, that I desire you will confer with Bidloo and Laurence, whether some other plan might not be adopted. They have plied me so much with aperitives to open my stomach, that I am greatly reduced ; my condition is, I think, hazardous, unless you try other measures." The King seldom spoke so long at a time, his conversation being usually remarkably dry and repulsive; and here His Majesty's speech was interrupted by a deep cough, and he sunk back in his chair exhausted. " May it please Your Majesty," said Dr. RadclifTe, " I must be, plain with you, Sir : your case is one of danger, no doubt, but if you will adhere to my pre- scriptions, I will engage to do you good. The rheum is dripping on your lungs, and will be of fatal consequence to you, unless it be other- wise diverted." — Upon this Dr. Bidloo, who, though expert in the knowledge of some branches of physic, was not always happy or quick in his conjectures, was about to reply. * Earl of Rockford. RADCLIFFE. 9 There was something like an insinuation of mala praxis in the last observation; and being somewhat of an irascible temper, the Dutchman, anxious perhaps to return to his duties of professor of anatomy and surgery at Leyden, was indifferent about giving offence to his royal master. But the King, in a calm and sullen manner, imposed silence, and inti- mated to the physicians to withdraw and con- sult upon the treatment of his malady. The consultation was short, and the result was, that some medicines should be tried that might have the effect of promoting the flow of saliva. This treatment fully succeeded, for the King was so completely restored, that a few months afterwards he fought the battle of the Boyne. Before we left the palace, my master waited upon Her Majesty the Queen; and as it was well known, that Mary grew weary of any body who would not talk a great deal (while her sister the Princess Anne of Denmark was so silent that she rarely spoke more than was necessary to answer a question) , our audience was not soon over. It was said by the ene- mies of the Queen, that whatever good quali- 10 RADCLIFFE. ties she had to make her popular, it was but too evident, by many instances, that she wanted bowels; but on the present occasion the accusation was quite untrue, for on the subject of the King's indisposition, nothing could exceed her anxiety, and it was impossible for the physician to answer Her Majesty's in- numerable inquiries. What was the nature of his complaint? the probable issue? how long a time would be required to complete his re- covery, so that, in the present critical state of affairs, His Majesty might be enabled to return to the management of public business, and take the field against his enemies? In fact, the Queen asked questions which I soon found, by a very little experience, that the con- jectural nature of the art of medicine would not always allow to be answered with preci- sion. The person of the Queen was majestic, and calculated to inspire respect ; and her con- versation (when not under the influence of such feelings as now agitated her) indicated a fine and cultivated understanding, for she had read much in history and divinity. Her Majesty's studies were, however, even now beginning to be interrupted by a course of RADCLIFFE. 11 humours that was forming in her eyes, and which compelled her to employ her time in another manner. But she was ever active; and so industrious, that she wrought many hours a day herself, with her ladies and maids of honour working about her, while one read to them all. Our interview with the Queen took place in a small apartment, afterwards known by the name of the Patch-work Closet, the sides of which were hung with tapesty, the work of her own hands; as were also the coverings of the chairs with which the room was fur- nished. As I shall not have occasion again to speak of the Queen, it may here be mentioned that, five years afterwards, this incomparable Princess fell a victim to the small-pox; and though my master was blamed by his enemies, as having caused her death, either by his negligence or unskilfulness, yet he himself always maintained that he was called too late, and that no remedies that could then be tried had the least chance of doing her good. On this delicate point, any evidence which I could advance would be received with suspicion; and it remains only to observe, that on this 12 RADCLIFFE. melancholy occasion King William exhibited feelings which no one had previously given him credit for. A great politician and soldier, who had been immersed in dangers and calami- ties from his infancy, he was possessed of boundless ambition, which he concealed under a cold exterior, never allowing his speech to betray the wishes of his heart. But during the last sickness of the Queen, His Majesty was in an agony that amazed every one about his person, fainting often, and breaking out into most violent lamentations. When he heard of her death, he was much affected, burst into tears, and for some weeks after was not capable of minding business or of seeing company. Whilst the nation was grieving for the loss of the Queen, an event took place in our domestic establishment, which considerably ruffled my master's temper, and interrupted, for a short space, the usual gaiety of his life. Though it could not be said that our house was ever a melancholy one (in truth, we were little at home, the Doctor living much in so- ciety, whither I accompanied him to taverns and clubs, where the choicest spirits were wont RADCLIFFE. 13 to assemble), yet still the home of a bachelor is occasionally but a dull and stupid residence. The friends of Radcliffe were therefore always urging him to look out for a wife, and he at length listened to their advice. One who was so general a favourite in society, and, besides, who was known to be so well to pass in the world (for at that time he was worth, at the least, £30,000, and daily adding to his wealth) , had no great difficulty in meeting with an ob- ject upon whom to place his affections. A young lady, the daughter of a wealthy citizen, whose name I forbear to mention, in considera- tion of the awkward disclosure which ulti- mately took place, soon attracted his attention. She was an only child, not more than twenty- four years of age, and with a tolerable share of personal charms: the parents readily as- sented to the proposal, and the terms of the marriage were soon agreed upon ; the lady was to have £15,000 down, and the residue of the citizen's estate at his decease. The visits of my master into the city were numerous, but he took me with him once or twice only. To tell the truth, I felt myself, on these occasions, quite misplaced ; not that I was at all unaccus- 14 RADCLIFFE. tomed to female society — quite the reverse; but then the conversations, with which I was familiar, were altogether so different. Here were none of the ordinary questions about health, the last night's repose, the situation of pain, the long detail of complaints, the va- pours, the low muttering with the waiting- woman aside; and at last, when the hurry and agitation occasioned by the doctor's arrival had subsided, the sagacious feeling of the pulse. To all this I was daily habituated; but, in the new scene to which I was now introduced, I was conscious of making an awkward appear- ance, and was glad to be left at home. Mat- ters, however, seemed to proceed prosperously, and every thing promised a consummation of my master's happiness ; when, one evening, he returned late to his home, obviously much dis- composed. He was no sooner alone in his chamber, than he gave vent to his chagrin. "Good God!" said he, as he paced up and down the room, "what a discovery! Well! hanging and marrying certainly go by des- tiny; and if I had been guilty of the last, I should scarcely have escaped the first. What would my acquaintance have said? And my RADCLIFFE. 15 neighbour, Sir Godfrey, how would he have triumphed! He was sarcastic enough the other day about that confounded garden- door * — here there would have been no bounds * The story, to which allusion seems here to be made, is thus related in the life of Radcliffe: " It will not be much out of the way, to insert a divert- ing passage between Sir Godfrey Kneller, the King's chief painter, and the doctor, since it happened near this time; and though not altogether so advantageous to the doctor's memory as the generality of his sarcastical re- plies, yet will be of use to bring in a very happy turn of wit from him that speaks in rejoindre to it. The doctor's dwelling-house, as has been said before, was in Bow-street, Covent Garden, whereunto belonged a very convenient garden, that was contiguous to another, on the back of it, appertaining to Sir Godfrey, which was ex- tremely curious and inviting, from the many exotic plants, and the variety of flowers and greens, which it abounded with. Now, as one wall divided both inclosures, and the doctor had some reason, from his intimacy with the knight, to think he would not give a denial to any reason- able request, so he took the freedom when he was one day in company with the latter, after extolling his fine parterres and choice collection of herbs, flowers, &c. to desire the liberty of having a door made, for a free inter- course with both gardens, but in such a manner as should not be inconvenient to either family. " Sir Godfrey, who was and is a gentleman of extraor- 16 RADCLIFFE. to his mirth; I should have been the laughing- stock of all who know me. " Mrs. Mary is a very deserving gentle- dinary courtesy and humanity, very readily gave his con- sent ; but the doctor's servants, instead of being strict ob- servers of the terms of agreement, made such a havock amongst his hortulanary curiosities, that Sir Godfrey was out of all patience, and found himself obliged, in a very becoming manner, to advertise their master of it, with his desires to him, to admonish them for the forbearance of such insolencies; yet notwithstanding this complaint, the grievance continued unredressed; so that the person aggrieved found himself under the necessity of letting him that ought to make things easy know, by one of his servants, that he should be obliged to brick up the door, in case of his complaints proving ineffectual. To this the doctor, who was very often in a cholerick temper, and from the success of his practice imagined every one under an obligation of bearing with him, returned answer, ' That Sir Godfrey might do even what he pleased with the door, so that he did not paint it : ' alluding to his employ- ment, in which none was a more exquisite master. Here- upon a footman, after some hesitation in the delivery of his message, and several commands from his master, to give it him word for word, told him as above. ' Did my very good friend, Dr. Radcliffe, say so? ' cried Sir God- frey : ' go you back to him, and, after presenting my service to him, tell him that I can take anything from him but physic' " — (The Editor.) RADCLIFFE. 17 woman, no doubt; but her father must par- don me, if I think her by no means fit to be my wife, since she is or ought to be another man's already! " These and other similar ex- pressions escaped him, as he continued to walk to and fro, apparently in the highest degree of excitement. At length he sat down to his table and wrote a letter to Mr. S — d, declin- ing the honour of becoming his son-in-law, and stating his reasons in full for so sudden a change of resolution. The effects of this dis- appointment were visible for some time, but he ultimately recovered his spirits, returned to his former aversion to matrimony, and resumed his usual habits of conviviality and indepen- dence. His practice increased, and there were few families of any note that had not some time or other recourse to his skill and advice. I began now to consider how his superiority over his rivals was to be explained, whence arose the great confidence reposed in him by his patients; to what, in fine, his eminent suc- cess was to be attributed. It was clear, his erudition had nothing to do with it; but though there was something rude in the man- 18 RADCLIFFE. ner in which he frequently disparaged the practice of others, yet it could not be denied that his general good sense and practical knowledge of the world distinguished him from all his competitors. He was remarkable for his apt and witty replies, and always ready in suggesting expedients ; though, to be sure, some of them were homely enough, and occasion- ally sufficiently ludicrous, and such as I never witnessed with the grave and more polished doctors into whose hands I afterwards passed. He was once sent for into the country, to visit a gentleman ill of a quinsey. Finding that no external nor internal application would be of service, he desired the lady of the house to order a hasty-pudding to be made: when it was done, his own servants were to bring it up, and while the pudding was preparing, he gave them his private instructions. In a short time it was set on the table, in full view of the patient. " Come, Jack and Dick," said Rad- cliffe, "eat as quickly as possible; you have had no breakfast this morning." Both began with their spoons, but on Jack's dipping once only for Dick's twice, a quarrel arose. Spoon- fuls of hot pudding were discharged on both RADCLIFFE. 19 sides, and at last, handfuls were pelted at each other. The patient was seized with a hearty fit of laughter, the quinsey burst and dis- charged its contents, and my master soon completed the cure. So much for his humour; but it was the confident tone in which he frequently pre- dicted the issue of diseases, a quality which he possessed in an eminent degree, and often exercised with great success, that chiefly gave a decided advantage to Radcliffe over his rivals in practice. I will relate one of these occasions, which was very striking. Being sent for once, to attend the Duke of Beaufort at Badminton, who was very ill, the Doctor, instead of complying with the request, told the gentleman who brought the message, " There was no manner of necessity for his presence, since the Duke his master died such an hour the day before: " which the messenger on his return found to be true. By the judicious exercise of this foresight a physician acquires the greatest reputation, and when his prognosis is the result of mature experience, he is entitled to be bold. Besides, the fears, the doubts, and anxiety of the 20 RADCLIFFE. friends of the sick ought to be taken into ac- count: they have a right to the consolation of certainty; and the doctor ought not to be over-scrupulous of his reputation, nor entrench himself too much in the security of an am- biguous reply. His duties demand discretion and humanity: in circumstances of danger, he is called upon to give to the friends of the patient timely notice of its approach; to the sick, he should be the minister of hope and comfort, that by such cordials he may raise the drooping spirit and smooth the bed of death. That " the Doctor should go out at one door when the Clergyman enters in at the other," is a quaint conceit, more expres- sive of impiety than humour; for even when the life of the patient is absolutely despaired of, the presence of a man of a compassionate and feeling heart will prove highly grateful and useful to the dying sufferer, as well as to his nearest relations. The health of King William continued toler- ably good till after his return from abroad in 1697, on the ratification of the celebrated treaty of Ryswick, when my master was again sent for to visit his royal patient. After rather RADCLIFFE. 21 jocosely illustrating His Majesty's situation "by an allusion to one of 2E sop's fables, which the King (previously to our arrival) was read- ing, in Sir Roger L'Estrange's translation, I was rather startled at the blunt manner in which Radcliffe told his patient that he must not be buoyed up with hopes that his malady would soon be driven away. " Your juices are all vitiated, your whole mass of blood cor- rupted, and the nutriment for the most part turned to water: but," added the Doctor, " if Your Majesty will forbear making long visits to the Earl of Bradford, (where, to tell the truth, the King was wont to drink very hard, ) I'll engage to make you live three or four years longer; but beyond that time no physic can protract Your Majesty's existence." I trem- bled at the bold and familiar tone assumed by my master, as well as at the positive prognosis which he ventured to give; but his prediction was verified by the sequel. King William died in 1702. The year before this event, Dr. Bid- loo had accompanied His Majesty to Holland, where his treatment of his royal patient at that time, and for some months before his death, was a subject of animadversion with 22 RADCLIFFE. the other doctors attached to the court. In addition to many other infirmities under which the King laboured, he was troubled with boils that formed in different parts of his body; and for these Bidloo directed that his feet and legs should be rubbed night and morning, with flannel covered with powder of crabs'-eyes, flour, and cummin-seed. As to diet, the Doc- tor was exceedingly indulgent, allowing His Majesty to drink cider, ale — in short, all sorts of strong beer ; and to take crude aliments be- fore going to bed. It was in vain that Doctors Hutton, Millington, Blakemore, and Laurence remonstrated. On the King's return to Hampton Court, the dropsical swelling of the inferior extremities extended upwards, for which Bidloo prescribed a vapour-bath, and in- closed the legs of the patient in a wooden box constructed for that purpose. In a constitu- tion so weak, which this treatment was reported to have still more debilitated, an accident was likely to prove fatal. On the 27th of Febru- ary, 1702-3, while hunting, the King fell from his horse, and broke his right clavicle near the acromion. This occurred in the neighbourhood of Hampton Court; but the French surgeon RADCLIFFE. 23 Ron j at was at hand, and soon reduced the fracture. But when he wanted to bleed His Majesty, a new obstacle arose, for it was neces- sary not only to have the sanction of some one of the court physicians, but also the authority of the privy council, for the performance of that operation. Notwithstanding the necessity and advan- tage of rest, the King persisted in his wish to return to Kensington, where he arrived be- tween nine and ten o'clock in the evening : here a discussion arose between Bidloo and the Surgeon as to whether there had really been any fracture or not. Ron j at stoutly main- tained the affirmative; the Dutch Doctor as stoutly denied it. This point was, -however, at length settled, when a new difference of opinion occurred as to the mode of applying the bandages. Bidloo wished himself to apply them, but the Surgeon said no, " You are here either in the character of a physician or in that of a surgeon: if the former, you have nothing to do with bandages, if the latter, c'est moi qui suis le premier chirurgien du Roi." After the death of the King, a paper war took place, and the various arguments and 24 RADCLIFFE. statements advanced by each party were fre- quently mentioned in societies where I was present ; for luckily my master had no share in these disputes. On the one hand Bidloo put forth a pamphlet *, published at Leyden, written in Low Dutch, in order, as his ene- mies said, that few might read it in this country; the year after, M. Ron j at entered the field in a French reply t, published in London by Henry Ribotteau, Bookseller in the Strand, over-against Bedford's Buildings. Of the public and private character of King William, a prince so celebrated in the history of that period, it would be presumption in me to speak. No one can deny that by his talents as a negotiator in the cabinet, he saved his own country from ruin, restored the liber- ties of England, and preserved the indepen- dence of Europe. His great object in accept- ing the crown of this country was to engage her more deeply in the concerns of the Con- * Verhaal der Laatste Ziekte en het overlij den, van Willem de Derde, &c. &c, in Leide, 1702. f Lettre de M. Ronjat, Premier Chirurgien de feu Sa Majeste Britannique Guillaume III.; ecrite de Londres a un Medecin de ses Amis en Hollande. RADCLIFFE. 25 tinent, and thus enable him to gratify his am- bition, the scope of which had always been to humble the French. When he found, however, the year after his arrival in Eng- land, that the spirit of party ran so high here as to thwart all his measures, he re- solved to quit the country altogether, go over to Holland, and leave the government in the Queen's hands. And yet it is singular that William was naturally of so cold and reserved a disposition, that Her Majesty knew nothing of this important determination, in which she was so nearly concerned, till she heard it from Bishop Burnet. It was said also, that the King, though he occasionally put on some appearance of application, was averse from business of all sort, and that it was to avoid company and occupation, that he betook him- self to a perpetual course of hunting. Of his own personal safety he was very regardless, and perhaps his belief of predestination made him more adventurous than was necessary. The most striking feature of his character was, however, as has been mentioned before, the gravity of his deportment; and Burnet used to relate, that on the most critical occa- 26 RADCLIFFE. sion of his life, on his landing at Torbay, in 1688, the King shook him heartily by the hand, asked him if he would not now believe in pre- destination; was, for a short time only, cheer- fuller than ordinary, but soon returned to his usual gravity. I do not vouch for the truth of this story, nor for the scrupulous accuracy of the Bishop in all which he relates, though I have heard that he is the best and indeed the only authority to be met with on many of the subjects he treats of. The repulsive quali- ties of the King were the cause, no doubt, of the coolness that subsisted between the dif- ferent members of the royal family. I recol- lect there was much talk at the time, of the affront put upon the Prince of Denmark, who, on his accompanying the King to Ireland, was not allowed to go in the coach with him, though it was well known that the Prince had put him- self to great expense on the occasion of that expedition. The Princess, afterwards Our Gracious Majesty Queen Anne, was treated even with still less courtesy; for, while she was dining one day with the King and Queen, His Majesty ate up all the green pease, then newly RADCLIFFE. 27 come in, without even once offering that rarity to his royal consort or guest. Of Prince George of Denmark I have little to say, for his physician was Dr. Arbuthnot. His Highness was an invalid, labouring, like the King, under an asthma; and during his illness, which was protracted, his Queen was very attentive to him. He died six years after King William. He had the Danish countenance, blonde, was of few words — spake French but ill, seemed somewhat heavy, but had the character of a good mathematician. He made no figure in politics, and did not understand much of the post of High Admiral, which he filled, though he possessed many good qualities ; was brave, mild, and gentle. - But I must descend from these high mat- ters, and speak again of my master, and, I am sorry to say, of another disappointment which occurred in our house. Two years after the death of Prince George, when Radcliffe was in his sixtieth year, I was somewhat sur- prised, one morning after breakfast, to ob- serve him attired with more than ordinary exactness. His full-bottomed wig was dressed with peculiar care; he had put on his best suit 28 RADCLIFFE. of lilac-coloured velvet with yellow basket but- tons, and his air upon the whole was very commanding. He reminded me strongly of his appearance some ten or fifteen years be- fore. He had an elevated forehead, hazel eyes, cheeks telling of the good cheer of for- This sketch is from an original picture by his friend Sir Godfrey Kneller, which is placed in the Library of the College of Physicians, in one of the closets of which I am now immured. RADCLIFFE. 29 mer days, if any thing a little too ruddy; a double chin, a well-formed nose, and a mouth round which generally played an agreeable smile. When he sat in his easy chair, with his right hand expanded, and placed upon his breast, as if meditating a speech, and clearing his voice for the purpose of giving it utter- ance; his left wearing his glove, and resting on his side immediately above the hilt of his sword, which was a very usual attitude with him, he certainly had a most comely and well- favoured appearance. I love to dwell upon these particulars of my old worthy master; for to him I owe my first introduction into the world, and whatever celebrity my memoirs may hereafter- obtain. When fully equipped, he stepped into a gay gilt chariot, drawn by fresh prancing horses, the coachman wearing a new cockade, and our lacqueys looking with all the insolence of plenty in their countenances. We paraded the streets, passed through Covent Garden, and the most frequented parts of the town; but it grieved me to observe, that our glitter- ing equipage served only to provoke the smiles and ridicule of the malicious. To 30 RADCLIFFE. speak out, it was now notorious that the Doctor was in love, and that all this parade was for the purpose of captivating the young lady of whom he was enamoured. Suffice it to say, he was lampooned, proved unfortunate in his suit, and was styled by the wicked wits of the day " the mourning Esculapius," " the languishing hopeless lover of the divine Hebe, the emblem of youth and beauty." But more sober reflection and the busy duties of his profession soon withdrew his thoughts from these amorous toys, and he continued actively employed for a few years longer, though it was but too evident that his health and spirits were daily declining. About this time that celebrated warrior, Prince Eugene, so distinguished for his cam- paigns in Hungary and Italy, where he had gained such splendid victories over the Turk and the King of France, arrived in England. The object of his visit was to try if it were possible to engage our court to go on with the war, which met with great obstruction. But the juncture was unfavourable to his project; for on the very day before his arrival, his great friend and companion in arms, the RADCLIFFE. 31 Duke of Marlborough, was turned out of all his places. The days of intimacy between the Queen and the Duchess were at an end; and the endearing appellations of the " poor, un- fortunate, faithful Morley," and Mrs. Free- man, no longer marked the extraordinary terms of friendly intercourse which had sub- sisted between Her Majesty and a subject. The Prince was, however, caressed by the courtiers for his own worth; and though his negotiations went slowly on, he was enter- tained by most of the nobility, and magnifi- cently feasted by the city. My master invited His Highness to dinner; and a large party of the nobility, and several topping merchants, particularly some of those who had. formerly contributed to the Silesian loan, were en- gaged to meet him. The enmity of the Prince to every thing French was known, and it had been rendered still more notorious by his admirable reply to an insolent threat of the minister of the Grand Monarque, which was at this time in the mouth of every one. Louvois had intimated to the Prince, that he must not think of returning to France; to which the warrior replied, "Eugene entrera 32 RADCLIFFE. un jour en France, en depit de Louvois et de Louis." To do honour to such a guest was the ambition of Radcliffe; and in giving or- ders for dinner, " Let there be no ragouts," said he; "no kickshaws of France; but let us treat the Prince as a soldier. He shall have a specimen of true English hospitality. I will have my table covered with barons of beef, jiggets of mutton, and legs of pork." At the appointed hour the guests assembled, and the Prince charmed every one by his un- assuming modesty, his easy address and be- haviour. His aspect was erect and composed, his eye lively and thoughtful, yet rather vig- ilant than sparkling: but his manner was pecu- liarly graceful, and he descended to an easy equality with those who conversed with him. The shape of his person and composure of his limbs was remarkably erect and beautiful; still, with all his condescension, and though he was affable to every one, it was evident that he rather suffered the presence of much company, instead of taking delight in public gaze and popular applause. The entertain- ment of my master went off very well; all seemed to be pleased, though some of the RADCLIFFE. 33 courtiers indulged in a little pleasantry at the ample cheer with which the table groaned. The princely stranger expressed himself much satisfied, and was loud in his praise of some capital seven years old beer, which we hap- pened at that time to have in tap. I forgot to mention, that, a few years be- fore the period of which I am now speaking, I saw, for the first time, Dr. Mead, who was then beginning to be known as a man rising in his profession, and into whose hands I was afterwards destined to fall. He lived then in Austyn friers; and we found him one morn- ing in his library, reading Hippocrates; when the following dialogue took place between the two physicians : Radcliffe (taking up the volume of the venerable Father of Physic). "What! my young friend, do you read Hippocrates in the original language? Well, take my word for it, when I am dead you will occupy the throne of physic in this great town." Mead. " No, Sir; when you are gone, your empire, like Alexander's, will be divided amongst many successors." I felt that this courteous reply pleased 34 RADCLIFFE. my master mightily; and although Mead was even then known to be a man of great talent, had already written his treatise on Poisons, published several other works of merit, and was therefore in every respect deserving of the countenance and patronage of the eminent doctor of the day, yet I have myself no doubt that this well-timed compliment to Radcliffe's eminence served to cement the intimate friend- ship of these two physicians. The library of Mead was even at this time considerable. Many rooms of his small house were filled with books; and the two doctors indulged in a long chat. The conversation embraced many topics. Mead was very lively and entertaining; related several anecdotes of things which he had seen abroad; and de- scribed with great animation his joy on find- ing the Tabula Isiaca * in a lumber room at Florence. Upon this subject my master asked * The Tabula or Mensa Isiaca is one of the most con- siderable monuments of antiquity. It was discovered at Rome, in the year 1525. There are represented upon it various figures in bas relief, mixed with some hiero- glyphics, which are supposed to relate to the feasts of Isis. Many speculations have been advanced on the his- tory and date of this curious relic of ancient times. RADCLIFFE. 35 many questions, and appeared much struck with the advantage of foreign travel to a physician. On taking his leave, he again ex- pressed his admiration of the literary attain- ments of Mead, and said in a tone of great earnestness and sincerity — " Some day or other, the Alma Mater where I was bred shall receive from me substantial proofs of the true concern I feel for the welfare of the cause of learning: for as I have grown older, every year of my life has convinced me more and more of the value of the education of the scholar and the gentleman, to the thorough- bred physician. But," added he, " perhaps your friend here (pointing me to a folio edi- tion of Celsus which stood on one of the shelves of the library) expresses my meaning better than I can myself, where he says, that this discipline of the mind, ' quamvis non faciat. medicum, aptiorem tamen medicince reddit.'" Radcliffe, as if unwilling to trust himself with any farther quotation, embraced Dr. Mead, and hastened to his carriage. On the 1st of August, 1714, died Queen Anne; an event memorable in the life of Rad- cliffe. The domestic physicians of Her Maj- 36 RADCLIFFE. esty, assisted by Dr. Mead, had applied various remedies without success. It was reported that the privy council, as well as the Queen, had given orders that my master should be present at the consultation, and that he ex- cused himself under pretence of indisposition. The truth is, he was not in town at that time, but down at his country-house at Cashalton in Surrey, ill himself of the gout, which had seized his head and stomach. Yet notwith- standing this, the enemies of Radcliffe imputed the death of the Queen to his absence, and he was accordingly threatened with assassination. This unpopularity, undeserved as it was, made him keep his house, where, on the 4th of August, three days after the death of Her Majesty, Dr. Mead and his brother the lawyer came down to dine with him at two o'clock. In spite of the ill state of his health, the con- versation of two such good friends afforded him much pleasure and satisfaction. After dinner, his wonted good humour returned, and, taking me in his hand, he presented me, with the following discourse, to Dr. Mead: — " Though my life is, I dare say, pretty well known to you, yet I will mention some of the RADCLIFFE. 37 leading circumstances of it, from which per- haps you may be able to derive some instruc- tion. Since I began the study of medicine, I have devoted myself chiefly to a careful examination of the njost valuable modern treatises. In this particular I differ, I know, from you, who are a profound scholar; but my books have always been few, though I hope well chosen. When I was at the uni- versity, a few vials, a skeleton, and an herbal, chiefly formed my library. By following the dictates of common sense, while I practised at Oxford after taking my bachelor of medicine's degree, instead of stoving up my patients who were ill of the small-pox, as was done by the Galenists of those days, I gave them air and cooling emulsions, and thus rescued more than a hundred from the grave. I have always endeavoured to discountenance the attempts of quacks and intermeddlers in physic, and by the help of Providence I have succeeded most wonderfully. My good Dr. Mead, you must consider this conversation as quite confiden- tial, and if I mention any thing that has the air of boasting, you will reflect that I unbosom myself to a friend, and what I am about to 38 RADCLIFFE. say is for your encouragement. In 1686, I was made principal physician to Her Royal Highness the Princess Anne of Denmark, and soon after His late Majesty King William's arrival in England, he was graciously pleased to make me an offer of being sworn one of his physicians in ordinary, with a salary of two hundred pounds per annum more than any other. At the same time he generously ordered me five hundred guineas out of the privy purse for the cures of M. Bentinck and M. Zulestein. Though I begged to be per- mitted to refuse the post, yet the King was so frequently ill of rheum and asthma, that, for the first eleven years of his reign, I gained, one year with another, more than six hundred guineas per annum by my attendance upon His Majesty. My practice rapidly increased, and I was even credibly informed that Dr. Gibbons, who lived in my neighbourhood, got more than one thousand pounds a year by pa- tients whom I really had not time to see, and who had therefore recourse to him. As my wealth increased, you will naturally ask me why I never married: it does not become me to speak of my good or ill fortune in that RADCLIFFE. 39 line, especially now when I ought to call my thoughts from all such vanities, and when the decays of nature tell me that I have only a short time to live. That time is, I am afraid, barely sufficient to repent me of the idle hours which I have spent in riotous living ; for I now feel, in the pain which afflicts my nerves, that I am a martyr to excess, and am afraid that I have been an abettor and encourager of in- temperance in others. Though by an indis- creet speech I lost the good graces of the Prin- cess Anne, yet His Majesty King William still continued to have confidence in my skill. As a proof of it, I may mention that in 1695 I was sent for to Namur, to cure Lord Albe- marle. After a week's residence in the camp abroad, His Majesty generously gave me an order on the Treasury for £1200; and his Lordship presented me with four hundred guineas, and this diamond ring, which I have' always worn since. As to honours, I have always refused them: a baronetcy was offered me, but of what use would a title have been to me, who have no descendants to inherit it? I have always lived in a state of celibacy, and have uniformly replied to those who formerly 40 RADCLIFFE. urged me to marry some young gentlewoman to get heirs by, that truly I had an old one to take care of, who I intended should be my executrix, as Oxford * will learn after my * By his will he left his Yorkshire estate to the Master and Fellows of University College for ever, in trust for the foundation of two travelling fellowships, the overplus to be paid to them, for the purpose of buy- ing perpetual advowsons for the members of the said College. .£5,000 for the enlargement of the building of Uni- versity College, where he himself had been educated. .£40,000 for the building of a library at Oxford. £500 yearly for ever, towards mending the diet of St. Bartholomew's Hospital. After the payment of these bequests, and some legacies to various individuals mentioned in the will, he gave to his executors, in trust, all his estates in Buckingham- shire, Yorkshire, Northamptonshire, and Surrey, to be applied to such charitable purposes as they in their dis- cretion should think best; but no part thereof to their own use or benefit. The RadclifFe Library, which is perhaps the most beautiful building in Oxford, was finished in 1749, when it was opened in a public ceremony: it has been appro- priated, by a late resolution of the Trustees, to the recep- tion of books in medicine and natural history. But that classical city has to boast of two other edifices which bear the name of the same munificent benefactor, and in RADCLIFFE. 41 death. For, thanks to Providence, I have been very successful, from the very beginning of my professional life; and I had not been settled a year in London, when I got twenty guineas a day by my practice: and even Dan- dridge, the apothecary whom I patronised, died, as I am informed, worth more than £50,000. The liberality of my patients en- abled me to live and act in a generous manner. My fees were good: of which you may form some notion when I mention, that to go from Bloomsbury Square to Bow, I received five their building the Trustees have been equally attentive to the interests of science and humanity. The Observa- tory and Public Infirmary were both erected out of the funds of Dr. Radcliffe, by the Trustees of his will. The first of these edifices consists of a dwelling-house for the Observer, and is amply supplied with astronom- ical instruments: it is one of the buildings first asked for by foreigners who visit the University, and is re- markable for its beautiful staircase. The Radcliffe In- firmary was opened for the reception of patients, 1770. From time to time, according to their means and as opportunities present themselves, the faithful and en- lightened guardians of these funds have ever been found ready (in the exercise of the discretionary power with which they are entrusted) to contribute to every charitable and useful purpose. 42 RADCLIFFE. guineas. I do not tell this to you, my good friend, out of ostentation, but that it may serve as an encouragement to you to hear how the practice of physic has been remunerated." Here Radcliffe paused, and appeared ex- hausted by speaking so long at a time. Dr. Mead — " I feel infinitely obliged to you for your kind and confidential communication. No one in the least acquainted with the liber- ality of your conduct can for a moment accuse you of an ostentatious display of your wealth. The subject upon which you last touched, is one that has often excited my curiosity. I should like of all things to know, what Lin- acre got by his profession; how much Caius, Harvey, Sydenham, and other worthies of medicine received yearly for their professional labour. The honorarium or fee of a doctor, one would suppose, must always have been in proportion to the rarity of professional skill, though we must take into account the greater value of money in former times. There may be notices of this kind to be met with in dif- ferent books, but the only instances that oc- cur at present to my memory are mentioned by that great benefactor of our College, Bald- RADCLIFFE. 43 win Harney. In the valuable and entertain- ing account left by him of his contemporaries, he mentions, that about the year 1644, Dr. Rob. Wright, who died at the early age of twenty-eight years, was very successful in practice. The Latin expression (for his MS.* is written most elegantly in that language), is, I believe, as follows : ' Wrightus viocdum trimulus doctor, mille admodum coronatos, annuo spacio lucraretur/ Now, the coro- natus, usually called a broad-piece, was about twenty-two shillings in value, and the receipt of a thousand of these by so young a physi- cian, who had only been settled three years in the metropolis, is an instance of very singular good fortune indeed. " The next, is an account of a fee received by Harney himself, and is thus related in the MS. life of that excellent man: — " It was in the time of the civil wars when it pleased God to visit him with a severe fit of sickness, or peripneumonia, which confined * Bustorum aliquot Reliquiae. There is a copy of this curious MS. now in the College Library : it was purchased at the sale of Lord Verney's books, and presented to the College of Physicians by Dr. Munro, June 25, 1783. 44 RADCLIFFE. him a great while to his chamber, and to the more than ordinary care of his tender spouse. During this affliction, he was disabled from practice; but the very first time he dined in his parlour afterwards, a certain great man in high station came to consult him on an in- disposition — (ratione vagi sui amoris) — and he was one of the godly ones too of those times. After the doctor had received him in his study, and modestly attended to his long religious preface, with which he introduced his ignominious circumstances, and Dr. Harney had assured him of his fidelity, and gave him hopes of success in his affair, the generous soldier (for such he was) drew out of his pocket a bag of gold, and offered it all at a lump to his physician. Dr. Harney, surprised at so extraordinary a fee, modestly declined the acceptance of it; upon which the great man, dipping his hand into the bag himself, grasped up as much of his coin as his fist could hold, and generously put it into the doctor's coat pocket, and so took his leave. Dr. Harney returned into his parlour to din- ner, which had waited for him all that time, and smiling (whilst his lady was discomposed RADCLIFFE. 45 at his absenting so long), emptied his pocket into her lap. This soon altered the features of her countenance, who telling the money over, found it to be thirty-six broad pieces of gold: at which she being greatly surprised, confessed to the doctor that this was surely the most providential fee he ever received; and declared to him that, during the height of his severe illness, she had paid away (un- known to him) on a state levy towards a public supply, the like sum in number and value of pieces of gold; lest under the lowness of his spirits, it should have proved a matter of vexation, unequal to his strength at that time to bear; which being thus so remarkably re- imbursed to him by Providence, it was the properest juncture she could lay hold on to let him into the truth of it. It may be said," continued Mead, " that this was an extraor- dinary case, and the fee a most exorbitant one, which the patient paid as the price of secrecy: but the precaution was unnecessary (as it ought always to be in a profession whose very essence is honour and confidence) ; for the name of the generous soldier is never once mentioned in the life of Hamey, though 46 RADCLIFFE. I have good reason to believe he was no other than Ireton, the son-in-law of Cromwell." Radcliffe. " These are curious partic- ulars, and I thank you for them. To speak once more of my own good fortune, I found that, even seven years ago, to say nothing of what I have acquired since, upon inquiry into the bulk of my estate, both land and money, I was worth more than £80,000, which I then resolved to devote, all or most of it, to the serv- ice of the public. I hope, however, not- withstanding what I shall leave behind me, no one can accuse im of having been sordid in my lifetime, or in case of the private dis- tress of my friends, not to have instantly relieved them. I have never been such a niggard as to have preferred mountains of gold to the conversation and charms of society. Perhaps there was selfishness in this: for I never recollect to have spent a more delight- ful evening than that in the old room at the Mitre Tavern in Fleet Street, when my good friend Billy Nutley, who was indeed the better half of me, had been prevailed upon to accept of a small temporary assistance, and joined our party, the Earl of Denbigh, Lords Col- RADCLIFFE. 47 peper and Stawel, and Mr. Blackmore. But enough of this affair of money. To one so well skilled as yourself, I have not much to say on the subject of practice; but recollect, I beg of you, the treatment of small-pox. Combat the prejudices of mankind on that point. By insisting upon this, I lately saved the life of the young Duke of Beaufort. You have done much, by showing the advantage of employing aperient medicines in the decline of that distemper; and I much regret that the letter you wrote to Dr. Freind upon that matter, and which you permitted me to in- form him he might publish, has not yet seen the light. Go on as you have begun; and I confidently hope that something more may still be introduced into general practice by a physician of your good sense and liberal views, to mitigate the violence of that most formid- able disease. " But I am now drawing to a close. Last year, upon my being returned member of parliament for the town of Buckingham, I re- tired from practice, and I have recommended you to all my patients. Your own merit and acquirements will insure you success; but 48 RADCLIFFE. perhaps your career may be facilitated by what I have done for you. Recollect that the fame of a physician is subject to the caprices of fortune. I know the nature of attending crowned heads very well. But continue as you have commenced. Nothing could be better than the method you took for the preservation of her late gracious Majesty's health; though the people about her (the plagues of Egypt fall upon them!) put it out of the power of physic to be of use to her. But I was sorry to hear the other day, that your enemies have spread a report that, dur- ing the last days of the Queen's illness, you had pronounced that her Majesty could not live two minutes, and that you seemed uneasy it did not so happen. Tell me, I beg, the real state of the case." " You very well know," said Dr. Mead, "that her Majesty had been long corpulent; and that, in her latter years, the habit of her body became gross and unwieldy. For the most part she had a good stomach, and ate heartily. But by reason of her immoderate fatness, and her weakness, occasioned by the gout, she became so inactive that she used but RADCLIFFE. 49 little exercise. In the beginning of her Ma- jesty's illness, there was a difference of opinion among the doctors as to the propriety of giving the Jesuits' bark; but I will not enter into all the disputes which took place on that occasion. It is enough to state, that after the appearance of the imposthume on the left leg, and the coming on of the doziness which seized her on Thursday the 28th July, there was no doubt about the propriety of cupping her; and blisters were ordered, but not ap- plied, for what reason I know not. The next morning her Majesty was seized with an apo- plectic fit, attended with convulsions. After two hours and a half she recovered her senses, but lost them again next day, and- died the following morning." Radcliffe. " Well, I will inquire no further. I see your own modesty will not allow you to find fault with the injudicious practice and fatal security of your colleagues. I cannot but applaud your good feeling and liberality of sentiment; and wish you most heartily success in your future professional life. Accept this cane. It has accompanied me now for many years in my visits to the 50 RADCLIFFE. sick, and been present at many a consultation. Receive it as a token of my friendship, and prosper. f Te nunc habet ista secundum. 3 " Here a twinge of the gout interrupted the speech of my old master; and Dr. Mead shortly after left for London, taking me with him. Dr. Radcliffe died on the first of November, 1714, three months after the Queen; and it was said that the dread he had of the populace, and the want of company in the country vil- lage where he had retired, and which he did not dare to leave, shortened his life. MEAD. CHAPTER II. From the possession of a physician who was kind, generous, and social in the highest degree, but who was certainly more remark- able for strong good sense and natural sa- gacity than for literary attainments, I passed into the hands of an accomplished scholar. Dr. Mead was allowed even by his antagonists, themselves men of great erudition, to be artis medicce decus, vitce revera ndbilis, and one who excelled all our chief nobility in the en- 52 MEAD. couragement he afforded to the fine arts, polite learning, and the knowledge of antiquity. But though I had changed masters, it was no small satisfaction to me to return to the old House, for Mead not only succeeded Radcliffe in the greater part of his business, but re- moved to the residence which he had formerly occupied in Bloomsbury-square *. My pres- ent master, on commencing his profession, had first settled at Stepney, had then resided in Crutched, and afterwards in Austin Friers, for the purpose of being near St. Thomas' Hospital; but now the distance of his new abode obliged him to resign the situation of physician to that charitable establishment. About six months after the death of Rad- cliffe, I was present at a consultation between Sir Hans Sloane, Dr. Cheyne, and Mead. It was held on the case of Bishop Burnet, the prelate so celebrated for the " History of his own Time," and for the active part he had taken in the great transactions of that event- ful period. He had been taken ill of a violent cold, which soon turned to a pleurisy; and this in- * Afterwards inhabited by Sir John Rushout. MEAD. 53 creasing, and baffling all remedies, his worthy- friend and relation Dr. Cheyne called in the assistance of the two other doctors. Up to this time Burnet had enjoyed uninterrupted good health, which he attributed, not without reason, to his temperate habits. " I will give you," said the venerable patient to Dr. Mead (for the Bishop was now 72 years old), "a short outline of my course of life. In summer I have been in the habit of rising at five in the morning, in the winter at six; and I have always officiated myself at prayer, though my chaplains may have been present. I then took my tea in company with my children, and read the Scriptures with them. I have generally spent six or eight hours- a day in my study. The rest of the day has been passed by me in taking exercise, making friendly visits or cheerful meals. But now, to use an expression of my late gracious master King William, whom I knew well for sixteen years, I feel ' que je tire vers ma fin. J JJ The Doctors listened to the melancholy pre- sage of the Bishop, and having put the neces- sary questions to him, withdrew into the ad- joining apartment, for the purpose of consulta- 54 MEAD. tion. I was now in company with two physi- cians of great eminence, though of very dif- ferent characters. On the one side of me stood Sir Hans Sloane, who had shortly before been created a baronet by His Majesty George the First, being the first physician upon whom an hereditary title of honour had ever been conferred; in his person tall and well made, sprightly in conversation, easy, polite and en- gaging in his manners, by birth an Irish- man. On the other was Dr. Cheyne, a Scotch- man, with an immense broad back, taking snuff incessantly out of a ponderous gold box, and thus ever and anon displaying to view his fat knuckles: a perfect Falstaff, for he was not only a good portly man and a cor- pulent *, but was almost as witty as the knight himself, and his humour being heightened by his northern brogue, he was exceeding mirth- ful. Indeed he was the most excellent ban- terer of his time, a faculty he was often called upon to exercise, to repel the lampoons which * At this time he weighed more than thirty stone, though he afterwards, by changing his habits, and living on milk and vegetables, reduced himself to less than half that weight. MEAD. 55 were made by others upon his extraordinary- personal appearance. Nothing could be more striking than the contrast of the two cele- brated men before me. Sir Hans began by observing, that the age of the Bishop might throw a doubt over the propriety of more bleeding, but he had so often seen the advantage of repeated vene- section, that he had the greatest faith in that mode of treatment. " In one case partic- ularly which I saw abroad " — but here let me interrupt the Baronet for a moment, to make an observation, which in the many consulta- tions at which I have been present, has more than once occurred to me. These delibera- tions are generally proposed either because the attending physician is at a loss what further to suggest, or that he wishes naturally enough to divide the responsibility of the management of a dangerous disease. They are held for the most part upon ailments of a chronic nature, that is upon such disorders as afford time and opportunity to form the judgment, and decide upon a method of prac- tice; for it is lucky that in urgent diseases, or those which are called acute, the remedies 56 MEAD. are simple, and that where delay would be dangerous, the means of relief are obvious. In consultations, there is of course much scope for diversity of opinion, but in the whole range of the plausible reasoning which the conjec- tural science of medicine admits of, there is nothing so imposing as a case; it bears down all before it. One of the consulting Doctors, after hearing the history of the previous treat- ment, advances that he has seen a case similar to the one, now under consideration, in which he did so and so with manifest advantage ; the argument is irresistible — But this by way of parenthesis. " In one case particularly (said Sir Hans Sloane) which I saw abroad, I saved a man's life, who complained extremely of a great pain in his shoulder, or rather inside of his pleura an- swering to that part, which increased on breathing high, sighing or coughing, for the patient was troubled with a short cough. The man was on board a ship bound for England, and it was taken by all for sea sick- ness, but I told them, they were all deceived, and forthwith ordered him to be bled in the arm to about ten ounces, and gave him an MEAD. 57 emulsion, and a pectoral decoction of barley, liquorish and raisins. I immediately found him much better, and ordered him to con- tinue this, and to take of crab's eyes and sal prunellse, of each half a drachm, and to swal- low morning and evening the half on't, drink- ing afterwards a pectoral draught, and in case of relapse I ordered him to be bled again; which was necessary to be done, for the ship chirurgeon, contrary to my desire, gave him a vomit: the patient, poor fellow! knowing nothing of it, till it was down. His pains thus returned, and I bled him twice on two several days, and with an emulsion he was cured. I have found also (added Sir Hans), in similar cases great advantage in applying a hot bag of parched salt to the side; but bleeding is the main remedy. I have bled a patient five times in her foot and arm in twelve hours." Whilst the baronet was speaking, the countenance of Dr. Cheyne un- derwent various changes, and when mention was made of the emulsion, which if I am not mistaken, was a compound of linseed oil, sugar-candy, and decoction of barley, it as- sumed a very decided expression of disgust, 58 MEAD. for he was a bon vivant of the first order. To the further employment of venesection, he was rather averse, and insisted much upon the advanced age of the Bishop. " An old man's body (observed Dr. Cheyne), is like a plant dried by the sun, its fibres are stiff, and juices decayed, and not as in youth able to prepare new nutriment, to repair the loss of solids and fluids. For this decay of the humours, the cure of the cacochymia is necessary; and to renovate the solids, we find no help like warm bathing and unctions, and you yourself (said he archly to Sir Hans) must have remarked, in your own native country, that the Irish live long, who anoint themselves with salt butter." What the remedies were which were ulti- mately ordered for the aged Prelate, I do not now recollect, but his own prediction was soon after fulfilled, and he died on the 17th of March 1715. Of Sir Hans Sloane, I shall have occasion to speak again more than once, and I can do it with confidence, for I had many oppor- tunities of studying his peculiarities, and be- ing in his company, particularly at the con- versaziones which were held at his house in MEAD. 59 Great Russell-street, by Bloomsbury. It was' observed of him, that he was on these occa- sions rather a precise gentleman, and used to go out of temper, when his guests spilled the coffee over his carpets. But he was very lively in discourse, nor did he lack topics, and having been much abroad, loved to talk of his travels. When only in his twenty-eighth year, he had accompanied the Duke of Albemarle *, on his appointment to the government of the Island of Jamaica, in the quality of physician to his Excellency, being chiefly induced by his attachment to natural history, to under- take a voyage, which was not thought at that time of day to be altogether free from danger. As he was the first man of learning whom the love of science alone had led from England to that distant part of the globe, and was be- * During his stay in Jamaica, a vast treasure which had been sunk in a Spanish galleon, about forty-five years before, somewhere near Hispaniola, or the Bahama Islands, was brought into the Downs. It had been weighed up by some gentlemen, who were at the charge of divers, &c. to the enriching them beyond all expecta- tion. The Duke of Albemarle, as Governor of Jamaica, received for his share, about £90,000. A medal was struck on the occasion. 60 MEAD. sides of an age when both activity of body, and ardour of mind concur to vanquish diffi- culties, his travels were eminently success- ful. To say nothing of the other curiosities with which he enriched his native country, he brought home from Jamaica, and the other islands at which he touched, no fewer than 800 different species of plants, a number much greater than had ever been imported into England before by any individual. His stay in Jamaica did not exceed fifteen months, for the Governor died, and the Doctor re- turned home, and settled in London. About seven years before the scene at the Bishop's, he had published the first volume of his Voyage to the Islands of Madera, Barbadoes, Nieves, St. Christophers, and Jamaica, with the nat- ural history of the herbs, and trees, four-footed beasts, fishes, birds, insects, reptiles, &c, illus- trated with the figures of the things described, which had not heretofore been engraved. 3tt large copperplates, ag &ig as tfje life* This was his first contribution to the gen- eral stock of knowledge, and when questioned on the subject of his voyage, he was used to say, that independently of the gratifica- MEAD. 61 tion of a laudable curiosity, he deemed it a sort of duty in a medical man to visit dis- tant countries, for that the ancient and best physicians were wont to travel to the places whence their drugs were brought, to inform themselves concerning them. Speaking of the part of the globe which he had visited, he never ceased to deplore the irreparable loss of fame which this country had suffered, in not being the first to partake in the glory of its discovery. When Bartholomew Colum- bus, said Sir Hans, was sent to England by his brother Christopher, in 1488, to persuade Henry the Seventh to fit him out for this ex- pedition, a sea chart of the parts of the world then known was produced, and a proposal made to the King, but after much delay and many untoward circumstances, both the map and the proposal were disregarded, and the money that had at first been set apart for the purpose, and thought sufficient for the dis- covery of the New World, was ultimately ex- 1 pended in the purchase of a suit of fine tapes- try hangings, brought from Antwerp, and afterwards used for the decoration of Hamp- ton Court. 62 MEAD. The scene I have endeavoured to describe at the Bishop's may serve as a specimen of a consultation of that day, and has given me an opportunity of introducing to the reader a very distinguished person, for such certainly must Sir Hans Sloane be allowed to have been. About four years after the time I now speak, he was elected President of the College of Physicians; on the death of Sir Isaac Newton, was chosen to fill the chair of the Royal So- ciety; and after his own decease gave origin to the British Museum. It is not, however, my intention to follow Mead into all the details of his private prac- tice, but I will point out some of the material improvements introduced by him in his art, and the progress which the science of physic made in his hands. — Mr. Secretary Craggs applied to him, in 1719, to find out the most effectual method to prevent the spreading of the plague, which had proved so fatal that year at Marseilles. My master accordingly published a discourse on that subject, which was so well received as to go through no less than seven editions in a twelvemonth. The kingdom was at this time governed by Lords MEAD. 63 Justices, during the absence of His Majesty George the First, who was then in Hanover. An act of parliament was passed, in conse- quence of the advice given by Mead; but the Opposition of the day, chiefly with the view to thwart the Ministry, caused two of its wisest clauses to be given up the following year. These related to the removing of sick persons from their habitations, and the making of lines of demarcation about infected places. Against the adoption of these prudent pre- cautions an outcry was raised, that persons in office intrusted with such powers might be tempted to abuse them, and exercise their authority in a manner grievous to the subjects of the kingdom. Dr. Mead, on the other hand, contended, that Salus populi suprema lex est; and said that, if the plague should unhappily be brought again into England, he was sure the people themselves would cry out for help, notwithstanding wrong notions of liberty may sometimes overpossess their minds, and make them, under the best of govern- ments, impatient of restraint. A clamour like this will probably be always renewed whenever this subject comes to be discussed 64 MEAD. by the public; the bold and the ignorant will excite it for the purposes of gainful notoriety, and the selfish trader from a short-sighted view of his own immediate interest. " But suppose for a moment," said Mead in conver- sation with a friend, " that the laws of quaran- tine were useless, and that the fears enter- tained of the contagious nature of the plague were without foundation, how can the com- merce of this country be benefited by the abolition of these regulations here, unless the rest of civilized Europe adopt the same meas- ure, and agree, at a sort of general congress, to remove all restraints from their trade with the Levant? But," continued he, in an earnest manner, which had all the air of prophecy, " depend upon it, whenever the doctrine of non-contagion is revived in Eng- land (and it will be, even a hundred years hence), it will always excite alarm among the nations who are more prudent than ourselves, and less eager to entertain every kind of wild and visionary speculation. Incalculable mis- chief will be done by the broaching of this pernicious doctrine * : the speculators who * This anticipation was actually realized not two years MEAD. 65 adopt such opinions should at least keep them to themselves, or if they will continue their experiments, let them make them in corpore vili, and not upon subjects which involve the general welfare of the community." Two or three years after this, my master's attention was called to another matter of equal, or perhaps greater importance than the one just mentioned; and I had the satisfaction of witnessing another prodigious step made to- wards the improvement of physic. This was no less than the mitigation of that loathsome disease the small-pox, a malady more formid- able, and infinitely more fatal than the plague itself. Lady Mary Wortley Montague hav- ing returned to England in 1722, was deter- mined to introduce the practice of inoculating for the small-pox, which she had witnessed in the East, and having before had the opera- tion performed successfully upon her son at Constantinople, desired her family surgeon to ago; for the mere agitation of the Plague question in the House of Commons excited the greatest alarm among the maritime nations of Europe, and for several months vessels sailing from England were put into quarantine at the different ports in the Mediterranean. 66 MEAD. engraft her daughter also with that disease. The process was witnessed by three physicians and the family apothecary; but though the success was complete, the profession still re- mained in suspense, and caution prevented the repetition of the experiment. But Caro- line Princess of Wales, having nearly lost the life of one of her daughters, the Princess Anne, by small-pox, was desirous of having her children inoculated; and obtained from His Majesty George the First, that six condemned felons should be pardoned for the good of the public, on condition of their submitting to be inoculated. Five of the felons contracted the disease favourably; the sixth, who concealed having previously had the small-pox, was not infected — but all escaped hanging. At the suggestion of my master, the Chinese method was practised upon a seventh criminal, who was a young girl of eighteen years of age. He accordingly introduced into her nostrils a tent, wetted with matter taken out of ripe pustules, which nearly approaches to the prac- tice of the Chinese, who take the skins of some of the dried pustules which have fallen from the body, and put them into a porcelain MEAD. 67 bottle, stopping the mouth of it very closely with wax. When they have a mind to infect any one, they make up three or four of these skins (inserting between them one grain of musk) into a tent with cotton, which they put up the nostrils. In the case of the girl whom my master treated as above related, she, like those who were inoculated by incisions made in the skin, fell sick and perfectly recovered. The attention of the medical world was naturally much engrossed by this new method, and every one was discussing the nature of the small-pox, of which the contagious quality was one of the most remarkable properties. " How strange! " said Mead, " that this prop- erty, apparently so obvious, should, not have been noticed by every writer on the subject, from the very first appearance of this danger- ous malady among us. Yet Sydenham, dis- cerning, as he has been called, does not take the slightest notice of it, and perhaps even at this very day, had it not been for the intro- duction of this novel method of communi- cating it, its infectious quality might not have been universally admitted. One would sup- pose that the merest tyro in an apothecary's 68 MEAD. shop could not have seen half a dozen cases of the small-pox without being convinced that one person caught it from another. An addi- tional striking example of what has often been observed before, that the most plain and ob- vious truths lie undiscovered till accident bring them to light. — More than twenty years after this, Dr. Mead published a treatise on the small-pox and measles, which contained many valuable observations on both these diseases, and also strong recommendations of the prac- tice of inoculation. To this treatise, which is written in a pure Latin style, he subjoined a translation of Rhazes' commentary on the small-pox into the same language, a copy of which he had obtained from Leyden, through the assistance of his friend and fellow-student Boerhaave, with whom my master maintained a constant correspondence. The ingenuity of mankind is exercised upon no subjects with so much pertinacity and acuteness as upon those connected with medi- cine, and it has often been disputed whether inoculation has lessened the number of deaths by small-pox. — One thing however is certain, that it has contributed to the comfort and se- MEAD. 69 curity of all prudent individuals and fam- ilies; for though it cannot admit of a doubt that many formerly passed through a long life without the disease, yet such a situation must have proved a constant source of uneasiness to themselves and friends, of restraint from many desirable pursuits, and at times of abso- lute seclusion from the world. The next improvement which Dr. Mead introduced into the practice of medicine was entirely of his own invention, and serves to show that his mind was not only capable of the extended views of philosophy, but was alive to the most minute circumstances that could contribute towards the perfection of his art. For the skill of a physician, though it assume a more exalted character when dis- played in the pursuit of general science, is equally conspicuous, and perhaps more imme- diately useful, when exerted in the discovery and employment of ingenious contrivances for the relief of suffering humanity. My master had often considered what could be the reason that, in cases of persons labour- ing under dropsy, when the water is suddenly drawn off, the patient swoons and frequently 70 MEAD. dies on the spot. A simple expedient oc- curred to him, which was this: during the operation of tapping, to make external pres- sure by the hands, and afterwards to apply a bandage to the belly. I was present when this method was first tried in the hospital, and afterwards frequently saw it used, more especially in the case of Dame Mary Page, wife of Sir Gregory Page, Bart., who was afflicted with this disease, and died March 4th, 1728, in the fifty-sixth year of her age. In sixty-seven months she was tapped sixty- six times and had two hundred and forty gallons of water taken away, without ever once fearing the operation *. This was cer- tainly a most valuable discovery, and shows the advantage derivable from the exercise of good sense and sound judgment; for Mead naturally reflected, that the removal of the pressure of the accumulated water caused the fibres suddenly to lose the extension which they had previously acquired; and it as na- turally occurred to him, that the tendency to * I have heard that all these particulars are carefully recorded on the monument of this dropsical lady, in Bun- hill Fields. MEAD. 71 faint could only be obviated by substituting an external support to the parts. But it is now time, after having related the benefits he conferred upon mankind by en- larging the boundaries of medical science, to revert to some details of a more domestic cha- racter. It has been mentioned before, when speaking of the first experiment of inoculation made in this country, that zeal for his profes- sion had on one occasion brought my master acquainted with the veriest outcasts of society, and in contact with convicted felons : it remains for me to relate how the calls of friendship and generous sympathy led him again within the walls of a prison. In politics Mead was a hearty Whig, but he reckoned amongst his friends many whose sentiments differed widely from his own. Garth, Arbuthnot, and Freind were among his chief associates : with the latter particularly he had always been on terms of the most friendly intercourse. Recently the intimacy of these two distinguished physicians had been much in- creased by a controversy in which they were embarked in support of their own enlightened views on the subject of the cooling treatment of 72 MEAD. the small-pox, against the attacks of the igno- rant and malevolent. About this time Dr. Freind had been elected member of parliament for Launceston in Corn- wall, and acting in his station as a senator with that warmth and freedom which was natural to him, he distinguished himself by some able speeches against measures which he disap- proved. He was supposed to have had a hand in Atterbury's plot, as it was then called, for the restoration of the Stuart family ; and hav- ing been also one of the speakers in favour of the Bishop, this drew upon him so much re- sentment that (the Habeas Corpus Act being at that time suspended) he was, on March 15, 1722-3, committed to the Tower. Here he lay a prisoner for some months, and my master did all he could to procure his liberation: during his confinement his practice fell chiefly into the hands of Mead. As soon as permission could be obtained, which was not till he had been some time in prison, we paid a visit to Freind, and entered that building whose low and som- bre walls and bastions have frowned on many an innocent and many a guilty head. When his room door opened, we found him MEAD. 73 in the act of finishing a Latin letter to my mas- ter, " On certain kinds of the Smallpox ; " and, as he perceived our approach, he came forward with an expression of great delight in his coun- tenance. " I was writing a letter to you, with the permission of the governor of the Tower; and you are indebted," he added in a low whis- per, " to my companion (looking at the warder, who was in the same chamber with his prisoner) for its brevity: for I don't find that his presence assists me much in composition." — During our interview, Freind told Mead that he passed his time not unpleasantly, for that he had begun to write the History of Physic, from the time of Galen to the com- mencement of the sixteenth century; -but that at present he felt the necessity of consulting more books than the circumstances in which he was now placed would give him an opportunity of perusing — " Though I ought not to repine," said he, " while I have this book (pointing to a Greek Testament, which was lying on the table), the daily and diligent perusal of which solaces my confinement. I have lately been reading the Gospel of St. Luke, and I need not point out to a scholar like yourself, and 74 MEAD. one who has paid so much attention to what I may call the medical history of the Bible *, how much nearer the language of St. Luke, who was by profession a physician, comes to the ancient standard of classical Greek than that of the other Evangelists. To be sure it has a mixture of the Syriac phrase, which may be easily allowed in one who was born a Syrian; yet the reading the Greek authors, while he studied medicine, made his language without dispute more exact. His style is sometimes even very flowing and florid — as when, in the Acts of the Apostles, he describes the voyage of St. Paul; and when he has occasion to speak of distempers or the cure of them, you must have observed that he makes use of words more proper for the subject than the others do. It is besides remarkable that St. Luke is more particular in reciting all the miracles of our Saviour in relation to healing than the other Evangelists are; and that he gives us one history which is omitted by the * This subject had long occupied the thoughts of Dr. Mead, although his treatise styled " Medica Sacra, sive de Morbis insignioribus qui in Bibliis memorantur, Com- mentarius/' did not appear till 1749. MEAD. 75 rest, viz. that of raising the widow's son at Nain." My master left the prisoner, with an assur- ance that he would use all the influence he possessed to procure his liberty: " For," said he, smiling, " however much your cultivated mind is enabled to amuse itself by reading and writing, I presume you will have no sort of ob- jection to resign your newly-acquired office of Medicus Regius ad Turrim */ J Very shortly afterwards, the opportunity of effecting this did actually occur; for when Sir Robert Walpole, the minister of the day, sent to consult Mead on account of an indisposition, he availed himself of the occasion to plead the cause of the captive. He urged, that though the warmth and freedom of Freind might have betrayed him into some intemperate observa- tions, yet no one could doubt his patriotic feel- ings and loyalty; that his public services had been great, for he had attended the Earl of Peterborough in his Spanish expedition as an army physician; and had also accompanied in the same capacity the Duke of Ormond into * This appointment was held by Dr. Gideon Harvey, from the year 1719 till 1754. 76 MEAD. Flanders ; that he deserved well of science, for he had done much to call the attention of the world to the new and sound principles of the Newtonian philosophy ; and was besides a man of excellent parts, a thorough scholar, and one whom all acknowledged to be very able in his * From a spirited medallion of Dr. Freind, carved in box-wood. There is a portrait of him in the hall of Christ Church, Oxford, upon which is inscribed the fol- lowing stanza from the pen of Anthony Alsop: Cui suas artes, sua dona laetus Et Lyram, et Venae salientis ictum Scire concessit, celerem et medendi Delius usum. MEAD. 77 * profession: and, finally, the Doctor refused to prescribe for the Minister unless the prisoner was set at liberty. He was almost immedi- ately relieved from prison, and admitted to bail; his sureties being Dr. Mead, Dr. Hulse, Dr. Levet, and Dr. Hale. The evening after this event, there was a numerous assembly at our house in Great Ormond Street, attracted by the hope of meet- * Mead's house, at the corner of Powis Place, now No. 49. There is a good garden behind the house, at the bottom of which was a museum. After Mead's death it was occupied by Sir Harry Grey, Lord Grey's uncle. 78 MEAD. ing Freind, and congratulating him on his lib- eration from the Tower. He came, and every one was delighted to see him once more at large. Besides the number of acquaintances and friends who were there, when it is observed that no foreigner of any learning, taste, or even curiosity, ever arrived in England with- out being introduced to my master ( as it would have been a reproach to have returned with- out seeing a scholar and physician who was in correspondence with all the literati of Europe) , it may easily be imagined that on so remark- able an occasion our conversazione was a crowded one. When the party broke up, and Freind and Arbuthnot were about to take their leave together, as they lived in the same part of the town — the former in Albemarle Street, and the latter in Cork Street, Burlington Gar- dens — Dr. Mead begged Freind to step with him for a moment into his own private study, which was a small room adjoining the library. There he presented him with the sum of five thousand guineas, which he had received from Freind's patients, whom he had visited during his imprisonment. On returning to the great room he wished them both good night, and MEAD. 79 jocosely said to Arbuthnot (who happened to hold the office of Censor of the College that year), "Now I commit our common friend here to your magisterial care and guidance; see that he does not again get into trouble; and on the least appearance of irregularity, re- port him to the President, Sir Hans Sloane. I look to you, Arbuthnot, to preserve har- mony * amongst us." These meetings, of which Dr. Mead was very fond, took place at stated periods, and the visitors assembled in the library, a spa- cious room about sixty feet long, of the rich- ness of which an idea may be formed by re- ferring to the catalogue of the sale of its con- tents, which took place after his death. The books, amounting to about ten thousand vol- umes, were sold in twenty-eight days. The sale of the prints and drawings occupied four- teen evenings, and the coins and medals were disposed of in eight days. But at the time of which I speak, all these literary treasures were * Arbuthnot was a dilettante in the art of music, and occasionally composed sacred pieces. One anthem by him, " As pants the hart," is in the collection of the Chapel Royal. 80 MEAD. collected under one roof; and the assemblage of marble statues of Greek philosophers, Ro- man emperors, bronzes, gems, intaglios, Etrus- can vases, and other rare specimens of antiq- uity, was most choice and valuable. Ranged along one side of the room stood the busts of the great English poets — Shakespeare, Milton, and Pope: they were of the size of life, of white marble, and by the hand of Scheemakers. The corner in which I was usually placed was between a statue of Hygeia * and a cabinet of iron which once belonged to Queen Elizabeth. This cabinet was full of valuable coins, among which was a medal of the Protector which Mead frequently exhibited as a curiosity to his visitors : it had Oliver's head in profile, with this legend, " The Lord of Hosts, the word at Dunbar, Sept. 1650; " on the reverse, the par- liament sitting. Placed in this favourite spot, I often over- * At Mead's sale this statue, three feet and a half high, was bought by Dr. Anthony Askew, for £50. On the same occasion, a magnificent statue of Antinous, of white marble and of the size of nature, was purchased by the Marquess of Rockingham, for £241. 10s. The celebrated bronze head of Homer was sold for £136. 10*. to Lord Exeter. MEAD. 81 heard very interesting discourse. On one oc- casion particularly, I recollect that the conver- sation turned on the condition and rank of physicians in society. The persons who took a leading part in the conversation were, if I remember rightly, my master, Dr. Freind, Dr. Arbuthnot, and Mr. Ward, the professor of rhetoric in Gresham College. The topic was suggested by some accidental allusion to the attack which had been lately made by Dr. Con- yers Middleton on the dignity of medicine, in a dissertation * written by him concerning the state of physic in old Rome. The indignation of the physicians of that day was naturally roused, and they were all up in arms against the author. Dr. Mead began by asking, " What class of men have deserved better of the public than physicians ? How much, for instance, does not this country owe to Linacre, the founder of our College? He was perhaps the most learned man of his time, and on his travels was received by Lorenzo de Medicis with the most marked distinction. That munificent patron of litera- * De Medicorum apud Veteres Romanos Degentium Conditions Cantab. 1726. 82 MEAD. ture granted him the privilege of attending the same preceptors with his own sons, and Lin- acre improved the opportunities he enjoyed with great diligence and success. At Flor- ence, under Demetrius Chalcondylas, who had fled from Constantinople when it was taken by the Turks, he acquired a perfect knowledge of the Greek language. " He studied eloquence at Bologna under Politian, one of the most elegant Latinists in Europe; and while he was at Rome he de- voted himself to medicine and the study of natural philosophy, under Hermolaus Bar- baras. Linacre was the first Englishman who read Aristotle and Galen in the original Greek. On his return to England, having taken the degree of M.D. at Oxford, he gave lectures in physic, and taught the Greek language in that university. His reputation soon became so high, that King Henry VII. called him to court, and intrusted him with the care of the health and education of his son Prince Arthur. To show the extent of his acquirements, I may mention, that he instructed Princess Catherine in the Italian language, and that he published a work on mathematics, which he dedicated to MEAD. 83 his pupil Prince Arthur. A treatise on gram- mar, which has universally been acknowledged to be a work of great erudition, is from the pen of Linacre: Melancthon, indeed, pronounces it to be inferior to none of its kind then ex- tant. In his own style he reminds one of the elegance of Terence, and in his medical * From a Portrait of Linacre by Holbein, in Kensing- ton Palace, a copy of which hangs over the fireplace in the Censor's Room of the College of Physicians. 84 MEAD. treatises very nearly approaches the clear and perspicuous language of Celsus. " Linacre was successively Physician to Henry the Seventh, Henry the Eighth, Ed- ward the Sixth, and to the Princess Mary. He established lectures on physic in both Uni- versities ; and he was the founder of our Royal College of Physicians, of which he was the first President, holding that office during the last seven years of his life. He was indeed," said Mead, " a most accomplished scholar: the Latin style of Linacre is so pure and elegant as to rank him amongst the finest writers of his age ; his friend Erasmus saying of him that he was ' vir non exacti tantum, sed severi judicii/ — Though the medical writings of Lin- acre are only translations, yet we cannot but form a favourable opinion of his professional skill, not only from the general estimation of his contemporaries, but from the sagacity of his prognosis in the case of his friend Lily the cele- brated grammarian, as well as from the ra- tional simplicity of the method by which he relieved Erasmus in a painful fit of the gravel." There was a pause here, and Mr. Professor MEAD. 85 Ward asked my master if it was true that Lin- acre had, in the latter part of his life, changed his profession, and entered into the priesthood. Mead. " Yes, it was undoubtedly true, but he still to his dying day had his thoughts upon physic, for it was towards the close of his life that he projected the College of Phy- sicians, of which he remained President till his death. It was also true that, on first ap- plying himself to the study of divinity, he was a most sincere searcher of the Scriptures, studying the Bible with great avidity; and that on reading the 5th, 6th, and 7th chapters of St. Matthew, he threw the book away, and swore that this was either not the Gospel, or we were not Christians." Freind. " Your account of Linacre is quite correct, and you have certainly not passed upon him a greater eulogium than he deserves. If any other example were required to prove to the world how much some of the members of our body have done to further the cause of learning, there is one very ready to be cited in the physician to whom we owe the 86 MEAD. compilation of the first annals of our College. Though an Englishman, we find Dr. Caius reading lectures on Aristotle in the university of Padua; and afterwards using the influence he possessed at court, where he was Physician to Queen Mary, in behalf of literature: for it was at his instance that a licence was obtained from the Queen to advance Gonvil-hall at Cambridge, and incorporate it under the name of Gonvil and Caius College. This College he endowed afterwards with considerable estates for the maintenance of an additional number of fellows and scholars. He was Fel- low, Censor, and President of the London Col- lege ; and even in advanced life never absented himself from our meetings without a dispensa- tion. He was buried in the Chapel of the Col- lege he had founded at Cambridge; and the simple inscription upon his monument, while it records the date of his death, adds a senti- ment which should reconcile us to the frail and doubtful tenure of our present existence, by the certainty and permanence of well- merited posthumous fame: — ' Fui Caius. Vivit post funera virtus. Obiit 1573, Mi. 63.' " MEAD. 87 Mead. " The zeal displayed by Caius in the cause of literature deserves every com- mendation, but it is perhaps more to our pur- pose to dwell upon the claim he has upon our grateful remembrance as the founder of the Science of Anatomy in England. According to the fashion of his day, he had gone abroad in pursuit of knowledge; at Padua had lived during eight months in the same house with Vesalius, and devoted himself with the same ardour to the studies of his celebrated com- panion: and let it never be forgotten that Caius, on his return from Italy, imbued with the spirit of inquiry and enlightened by the lamp of science lately kindled in that country, taught Anatomy to the Surgeons in their own Hall. Here, beyond the precincts of the Col- lege of Physicians, reflecting great honour upon that body, adding to his own reputation and conferring no small advantage on the Surgeons, he laid that solid foundation for the study of Anatomy, to which may easily be traced the glory and after discoveries of Har- vey. Caius began to lecture to the Surgeons soon after their incorporation (1540), and continued to do so, for twenty years, even 88 MEAD. after he had been elected President of our Col- lege and appointed Physician to the Court. The privilege which about this time had been granted to the Surgeons of obtaining annually four bodies of executed felons for the purpose of dissection, was doubtless the cause why the Hall of the Surgeons was selected for the lectures of Caius: for when in 1564 a similar permission was allowed to the Physicians by Queen Elizabeth, anatomical preelections were held at their own College. Dissections now began to be made frequently here, and the year before the death of Caius, an order is registered in our Annals that three bodies should be procured at the expense of the Col- lege, two sectionis eocperiundi causa, and the third to be made ' a public anatomy of.' But it is not only by reference to our Annals that it appears to have been the merit of Caius to have given the first impulse to these studies, for the fact is mentioned by contemporary writers. — William Bulleine, M. D., in a very curious book *, published in 1579, enumerates * A little dialogue between Soarenes and Chirurgi. — The name of Caius was spelt in many ways — Gauius, GaviuS; Kaius. Anglice — Kaye, Keye, Cay. MEAD. 89 among the cunning men, profitable to the com- monwealth, the learned Doctor, M. John Kaius, as the first who taught by learned lec- tures and the secrete anothomies, the worthy fraternity of Chirurgeons, of the most ancient and famous city of London." Dr. Freind. " I have not lately, as you all know, had an opportunity of consulting any books, but I recollect, some time ago, hav- ing obtained permission to examine the early volumes of our Annals, and being much struck with the importance attached to the study of anatomy by our ancestors, and the labour and assiduity with which they appear to have cul- tivated that science. If my memory does not fail me, it was in 1581, about eight years after the death of Caius, that a Lecture on Anatomy was regularly founded and endowed at the College. It was in that year that the Lord Lumley and Dr. Caldwall, signified their benefactions for that purpose, and the College to show itself worthy of the liberality of those generous patrons, though possessing very scanty funds, immediately voted all the money in their treasurer's hands to enlarge their 90 MEAD. building, render it more suitable to their meet- ings, and more convenient for the delivery of these public lectures. Their poor stock, it would seem, amounted only to <£100, but it must always be kept in mind that the funds of our body have never been replenished out of the coffers of the state, but have been fur- nished solely by the occasional donations of private individuals, or the legacies and con- tributions of its own members. In the time of the Protectorate their treasury was at its lowest ebb, and yet it is a subject of pride that even then the ardour of its members for anatomical research was unabated, for it was during this period that Glisson, whom your friend Boerhaave calls the ' most accurate of anatomists,' published his Lectures on the Structure of the Liver, dedicating his work to the University of Cambridge, ornatissimoque Medicorum Londinensium Collegio, thus avoiding, you observe, all allusion to the regal character of our foundation. But what won- der, when the sour and crabbed Republicans of those days were so cautious on this head, that in reciting the Lord's Prayer, they would not say — ' Thy kingdom come,' but always MEAD. 91 ' Thy commonwealth come.' — To return how- ever to the Lumleian Lectures, two years after their endowment, the College built a spacious Anatomical Theatre in Knight Rider Street, and here Harvey must have given his first public demonstrations of the circulation of the blood, for he was elected Reader * in Anatomy in 1615. The mention of Caius, Harvey, and Glisson, suggests the names of the other great anatomists of that age; and it cannot fail to strike us as a matter of won- der and admiration, that all the important dis- coveries in Physiology were made in a very short space of time. In the fifty years which elapsed from 1620 to 1670, greater strides were made in enlarging our knowledge of the functions of the living animal body, than had ever been made before, or will probably ever be made again. For reflect only, that in this interval the brilliant discoveries of the circula- tion of the blood, of the nature of respiration, * The term Reader (Praelector) seems to have gone into disuse, except perhaps at Oxford, where the " Reader in Anatomy " teaches that Science, in Christ Church, in a small but elegant Theatre, which gives the ill-omened name of Skeleton Corner to a thickly peopled, but very inconvenient angle of that distinguished College. 92 MEAD. of the curious system of vessels called lacteals, as well as of that to which the general name of absorbents has been given, took place. In fact the means by which we live and breathe, by which our bodies are nourished, grow, change, and finally decay, were for the first time pointed out and explained. " In 1622, Aselli discovered the Lacteals. " In 1628, Harvey published his Doctrine of the Circulation of the Blood. " In 1647, The Thoracic Duct and Recep- taculum Chyli were pointed out by Pecquet. "In 1651, The Lymphatics were demon- strated by Rudbeck. And " In 1668, Mayow taught that the oxygen of the air, which had lately been discovered, mixed with the blood in the lungs: in short, published a Theory, in which you will find the germ of all subsequent opinions on the na- ture of Respiration. "It is curious however to reflect that, not- withstanding the gigantic steps which Physio- logy was making at this time here, and in some parts of Europe, it remained stationary in others; in Germany, for instance, it seems to have been about this period pretty much in the MEAD. 93 same state in which it had been left by Galen, when the structure of apes was described as the anatomy of man. So late even as the middle of the seventeenth century, about the very time when Lower was making, at Oxford, the daring and original experiment of transfu- sion *, or causing the arterial blood of one ani- mal to pass into the jugular vein of another (which, by the by, was approved of by the * In 1665, Richard Lower made this experiment at Oxford; by means of long tubes, the blood of the verte- bral artery of one dog was made to pass into the jugular vein of another, and it appeared proved, that there was no reason to fear any mischief, and that the character or nature of one animal was not likely to be changed by inj ecting into its veins the blood of another. An experi- ment similar to this, which preceded it a few years, and which, like it, was founded on the doctrine of the circula- tion of the blood, viz. the injecting of various fluids im- pregnated with remedies into the veins of animals, was originally suggested by Sir Christopher Wren, the cele- brated architect. He was one of the early Fellows of the Royal Society, and being a man of the most universal accomplishments, was fond of the study of medicine, and occasionally employed his talents in the service of anatomical science; in proof of which, it may be men- tioned that he gave the original drawings for the plates which illustrate Willis' Anatomy of the Brain. 94 MEAD. Royal Society, before whom it was made, as an expedient likely to be useful after severe haemorrhages), a grave dispute arose in Ger- many, as to the position of the heart itself. The contest was terminated, at length, by the Professors of Heidelberg, where the question was agitated, having recourse to the delicate experiment of killing a pig in the presence of the Margrave of Baden-Durlach, and clearly proving to his Highness, who then laboured under palpitation of the heart, that it really was situated on the left side of the thorax. The result of this important discovery was fatal to the fortunes of his Highness' physi- cian; who, though he stoutly maintained by a refinement of courtly flattery, that the heart of his master could not have a position similar to that of a pig, was dismissed in disgrace. But it is unnecessary to dwell longer upon the superiority of our English anatomists, or to recapitulate the additions made to this branch of knowledge by the former Fellows of our College, for the Capsule * of Glisson, the Tu- * The general reader may require to be told, that these are terms applied to particular parts of the liver, the heart, and the brain: though the anatomist may be sur- MEAD. 95 bercle of Lower, and the Circle of Willis, are terms incorporated with the science itself, and, like the capes, islands, and bays, which bear the names of our early navigators, will serve to perpetuate the fame of these original dis- coverers. Of Willis, the last of these worthies whom I mentioned, let me observe, before I finish, that, though his Anatomy of the Brain is deservedly praised for the accuracy of re- search with which it abounds, yet it contains some notions rather fanciful, since he lodges sensation in the corpus striatum, memory and imagination in the medullary part of the brain *." The conversation now became more gen- prised, that in the enumeration are not included many other names derived from the discoverers of particular minute structures: more especially that no notice was taken of the claim which Willis has to the honour of having first proposed the classification of the cerebral nerves, now most usually adopted, and given denomina- tions to several of them, which they will most probably always retain. * What is this to the modern quackery of craniology, in which every faculty and feeling has a distinct organ, in which it is generated, which however it deprives of the merit, small as it is, of originality? 96 MEAD. eral: those who had listened to the display of learning and accurate research which Dr. Freind and my master had made, expressed their admiration at the prodigious acquisitions made by the science of medicine, during the first half of the seventeenth century, and each suggested some additional fact relating to that subject. Among others there was one whose name I cannot now recall, but who appeared to have devoted himself more particularly to the study of the Materia Medica, who ob- served, that this sudden and great increase of our knowledge of the animal economy, and consequently of our acquaintance with the true causes of disease, was perhaps not more remarkable than the important additions which were made about this time to our list of remedies. It was within the same memorable period, he said, that some of our most efficient drugs were either first made known to the world, or first introduced into general use. It will be sufficient to mention bark, ipecacu- anha, mercury, and antimony; to which four remedies, if we add opium, it may be ques- tioned whether we should not possess a toler- ably complete Materia Medica. The history MEAD. 97 and fate of medicines is a subject of great curiosity, depending upon the most fortuitous circumstances; for instance, according to the earliest account of the discovery of bark, its use was accidentally learned in the following manner: — Some cinchona trees being thrown into a pool of water in Peru, lay there till the water became so bitter that every body re- fused to drink it. However, one of the neigh- bouring inhabitants being seized with a vio- lent paroxysm of fever, and finding no other water to quench his thirst, was forced to drink of this, by which he was perfectly cured. He afterwards related the circumstance to others, and prevailed upon some of his friends, who were ill of fever, to make use of the same remedy, with whom it proved equally success- ful *. But it was not only the casual experi- ence of an uncivilized people which discovered this valuable remedy, but the first prejudices against its use, which were very strong, were counteracted by the influence of a religious * It is amusing to contrast this first rude natural in- fusion, with the present neat and condensed form of ex- hibiting the bark: for now a grain or two of the sulphate of quinine is the ordinary dose of the remedy. 98 MEAD. sect (the Jesuits), totally unconnected with the practice of medicine; and physicians were ultimately taught how to use it with effect by a man who was vilified both at home and abroad as an ignorant empiric. Sydenham, when speaking of bark, is very contradictory, and seems to have been afraid to employ it efficiently; and it was not till Louis the Four- teenth bought the secret of the method of giv- ing it, that the real virtues of this inestimable drug were jproperly felt and universally ac- knowledged. While Talbor, the person of whom the French King had made this pur- chase, was performing at Paris, about fifty years ago, the cure of Monseigneur, Madame de Sevigne, in one of her letters, describes, in the most amusing manner, the anxiety of every one at court, and the rage of M. D'Aquin, first physician to Louis : — " C'est dommage, que Moliere soit mort, il feroit une scene merveilleuse de D'Aquin, qui est enrage de n 'avoir pas le bon remede, et de tous les autres medecins, qui sont accables par les ex- periences, par le succes, et par les propheties comme divines, de ce petit homme. Le Roi MEAD. 99 lui fait composer son remede devant lui" &c. &c. Sir R. Talbor (for he was knighted) died the year after this triumphant exhibition of his skill, and Louis the Fourteenth then ordered the secret to be published for the bene- fit of the world. The same Monarch also first introduced ipecacuanha into general practice, having induced Helvetius to employ it largely for the cure of dysentery in the Hotel Dieu, about the year 1679. But antimony has had the most inconstant fortune, for though it was known and employed as a remedy as early as the twelfth century, yet Valentine the Monk gave it so indiscreetly, and made experiments with such ill success upon the unhappy brethren of his Convent, that the metal is said to have speedily returned to the mines whence it had recently emerged. Three hundred years afterwards it began to be talked of again; but in 1566, by a decree of the faculty of Paris, confirmed by an arret of Parliament, it was condemned as a poison, and was not al- lowed to be openly prescribed as a remedy till 1650; indeed it is chiefly to Sir Theodore Mayerne that we are indebted for the vari- 100 MEAD. ous preparations of antimony, as well as of those of mercury *. Dr. Mead. " It was fortunate that our knowledge of the means of combating disease kept pace with our more correct views of Phy- siology, and of course more distinct notions of morbid changes of structure. But to return to the subject of anatomy: when I was ap- pointed by the Company of Surgeons to read Anatomical Lectures in their Hall, which I did for six or seven years, I always insisted strongly upon the obligations their branch of the profession was under to the early Fellows of the College of Physicians, and I hope, as in- formation becomes more diffused, and scien- tific attainments more universal, the Surgeons themselves will not be so ungrateful as to for- get or disown it. " It would be easy to go on enumerating * The black wash now so generally used by Surgeons is a prescription of Sir Theodore Mayerne's, by the use of which he performed a great cure upon Sir Kenelm Digby. His formula is this: — 1^ . Aquae calcis % vj . Mellis rosati 3ii. Mercurii dulcis 5i. M. MEAD. 101 the medical men whose names are allied with the history of science and classical literature in England, but your own memories will fill up the catalogue. Our archives contain sev- eral MSS. which, if published, would benefit the republic of letters: I have often regretted that Harney's notes and criticisms upon the works of Aristophanes have never yet been given to the world." Freind. " It was intended that they should have been so. My friend the Bishop of Rochester recommended that they should be sent to Kuster, that learned critic to whom we owe the late excellent edition * of the Greek poet which was done in Holland; but the work was unfortunately too far advanced in the press before the offer was made, so that Harney's MS. still remains in the College Library." Mead. " I have been much amused with the character drawn of Harney by his bio- grapher : it is full of quaintness and antithesis ; and, if I recollect perfectly, is to the following * Called Editio Optima. 102 MEAD. effect. ' He was a consummate scholar with- out pedantry, a complete philosopher with- out any taint of infidelity; learned without vanity, grave without moroseness, solemn without preciseness, pleasant without levity, regular without formality, nice without ef- feminacy, generous without prodigality, and religious without hypocrisy.' — These are a few of the learned physicians who have been the pillars and ornaments of the pr6fession; * From a portrait of Hamey in the dining-room of the College. MEAD. 103 which, so far from having been considered formerly a degrading one, has not only been patronized by royal and noble benefactors, but we boast of some of the latter quality amongst our own body. The Marquess of Dorchester not only left us his library, enriched with the best books, but was enrolled amongst our Fel- lows, assisted at our meetings, and exerted himself in every possible way to promote the study of medicine." — [My master here grew warm, and turning round to Mr. Professor Ward, more particularly addressed himself to him:.] — "Why amongst the Athenians there was a law that no slave nor woman should dare to study medicine. Have not the greatest philosophers of antiquity devoted themselves to it? have not Pythagoras, Democritus, and Aristotle, written expressly upon botany, anatomy, and physic? It is well known that the inhabitants of Smyrna associated upon the coins * of that city the names of their celebrated physicians with the effigies of their gods. I am aware that * Some envious antiquary has lately insinuated that the coins from which Mead drew this inference were struck in honour of magistrates and not of medical men. 104 MEAD. amongst the Romans our art was not held in such high esteem; but it is well known that in the time of Julius Cassar, when physicians came from Greece (the country whence the Romans derived all their polite learning and knowledge of the fine arts), they were com- plimented with the freedom of the Eternal City, a privilege of which that proud people was extremely jealous." Aebuthnot. " What you have said will show the dignity of our art, and who will doubt of its liberality who reflects for a mo- ment on the generous and spirited conduct of our poor friend Garth, whose death we all deplore? To whom but a Physician was the corpse of Dryden indebted for a suitable in- terment? We all recollect how he caused it to be brought and placed in our College, pro- posed and encouraged a subscription for the expense of the funeral, pronounced an oration over the remains of the great Poet, and after- wards attended the solemnity from Warwick Lane to Westminster Abbey, where it was conveyed on the 13th May, 1700, attended by more than a hundred coaches. MEAD. 105 " But Garth was indeed the best-natured of men: besides being a polite scholar-, ever at- tentive to the honour of the faculty, and never stooping to prostitute the dignity of the pro- fession through mean or sordid views of self- interest f." * From a portrait of Garth by Sir Godfrey Kneller, in the Censor's Room of the College. f Will no one erect a monument to Garth? He and his wife are buried under the communion-table in the chancel of Harrow church, with nothing but the following rude inscription to mark the spot: — " In this Vault Lies ye Body of ye Lady Garth, Late 106 MEAD. Mead. " The loss of such a man we shall all long lament: besides there is something in the death of a colleague peculiarly melancholy. His mind has been formed by the same studies, the same motives must have actuated his con- duct, he must have been influenced by the same hopes and fears, and run pretty nearly the same career in life with ourselves; and at his death we are forcibly struck with the futility of all our plans, the emptiness and littleness of all our schemes of ambition. I know not when I have been more affected than in read- ing, a few days ago, the story of the death of Dr. Fox as told by Harney, in his Bustorum aliquot Reliquice. He was a younger son of Fox the martyrologist, and had been a warm friend and active patron of Harney, the great benefactor, and, as I may call him, second founder of our College. In that curious MS. which contains the characters of his contem- porary physicians, statesmen, and other cele- brated persons of his day, Harney speaks in Wife of Sir Samuel Garth, Kt. Who Dyed ye 14th of May, In ye year 1717. Sir Samuel Garth, Obijt jan e : the 18th, 1718." MEAD. 107 the most pathetic terms of the death-bed scene of his friend, and I will endeavour to recollect the precise Latin expressions in which Fox takes leave of him. Mi amice, vale; crastinus dies liberabit tuum ah his angustiis. Et vale diocisse iterum, porrec- tdque quam suspicabar frigidiore mauu } eoc- pressisse mihi lacrymas, meamque illam im- belliam, averso leviter capite, redarguisse et susurrasse. Hoccine est philosophari? et fructum promere tot colloquiorum? Harney adds, Victus ego dolore et pudore, me domum confero arbitratus in ista d^yavla levius fore audire ccetera quam videre. But let us change this melancholy subject. Tell us," ad- dressing Arbuthnot, " are we to expect an- other volume of the Memoirs of Martinus Scriblerus; or are Pope, Swift, and yourself tired of the project? I hope there is not an end of a scheme which was so calculated, by ridiculing the abuse of human learning, to benefit the cause of polite letters." The answer of that brilliant wit and scholar was unfavourable ; and it evidently ap- peared, from the dejected tone in which he 108 MEAD. spoke, that the change in the fortunes of the illustrious triumvirate which had been occa- sioned by the death of Queen Anne, had de- pressed his spirits, and terminated the plan. Most of the party had now assembled round Dr. Mead, to listen to this hasty recital of the merits of the distinguished physicians of former days. Of the names and persons of many of those present that evening, I have now no recollection: but, even at this distance of time, the figure of one who leaned on the arm of Arbuthnot is distinctly present to my imagination. He was protuberant before and behind, and used humorously to compare him- self to a spider; and was so feeble that he could not, as I have heard, dress or undress himself, and was always wrapped up in fur and flannel, besides wearing a bodice of stiff canvas. In this description every one will recognise the form of Pope. He took no part in the conversation; but his fine, sharp, and piercing eye, directed as it was alternately to the different speakers, indicated that he felt no common concern in the subject. But he did not stay long; pleading as an apology for his departure an attack of his old enemy the MEAD. 109 headach, and the intention of returning to Twickenham * that evening. As he passed by the spot in which I was placed, I heard him say to a friend who accompanied him, and who, like himself, had just taken leave of Dr. Mead: " I highly esteem and love that worthy man. His unaffected humanity and benevolence have stifled much of that envy which his eminence in his profession would otherwise have drawn out; and, indeed, I ought to speak well of his profession, for there is no end of my kind treatment from the faculty. They are in general the most ami- able companions and the best friends, as well as the most learned men I know." The party now moved to a little distance to inspect a bust of Harvey, which my master had lately caused to be executed by an excel- * This elegant villa had been recently purchased by the poet, with part of the money he had received for his translation of the Iliad; an enormous sum in those days, between five and six thousand pounds : but what was that in comparison with the hundred and twenty thousand pounds which the great popular author of the present time has received for the various works with which he has delighted and instructed the world? 110 MEAD. * lent hand, from an original picture in his pos- session. " This bust," said Mead, " I intend to present to the College, to replace in some measure the statue of Harvey which was and stood and which was no doubt lost in the great fire. I have long thought it a reproach that we should not at least possess a bust of him who, to use the erected to him during his lifetime, in the hall of our former building, Now placed in the Theatre of the College. MEAD. Ill strong and figurative language of the Latin inscription, gave motion to the blood, and origin to animals, and must ever be hailed by us Stator Perpetuus." Freind. " The skill of the sculptor has been succesfully employed here. The mild features of the old man are well expressed, and exhibit with fidelity his candid and gentle nature. I see him now, in my mind's eye, after the surrender of Oxford to the Parlia- ment, and the loss of his wardenship of Mer- ton College, in his retirement at Richmond. The visit paid him there by his intimate friend Dr. George Ent, is related in so lively and pleasing a manner, that one is almost present at the interview. It was in the year 1651, when Harvey was in his seventy-first year. ' I found him,' says Ent, ' in his seclusion, not far from town, with a sprightly and cheer- ful countenance, investigating, like Demo- critus, the nature of things. Asking if all was well with him, ' How can that be?' replied Harvey, ' when the state is so agitated with storms, and I myself am yet in the open sea? And, indeed,' added he, ' were not my mind 112 MEAD. solaced by my studies, and the recollection of the observations I have formerly made, there is nothing which should make me desirous of a longer continuance. But thus employed, this obscure life, and vacation from public cares, which disquiets other minds, is the medicine of mine.' Who does not admire," continued Freind, " the modest altercation that arose between the great discoverer of the circulation of the blood, and Dr. Ent, about the publication of those most valuable papers containing his Exer citations on the Genera- tion of Animals? One may imagine him re- plying to the importunity of his friend, that though, at his advanced age, it was of little consequence what the world thought of his writings, yet he could never forget, after the publication, at Frankfort, in 1628, of his doc- trine of the circulation of the blood, that such was the general prejudice against him as an innovator, that his practice as a physician con- siderably declined. To be sure, he might look upon himself as recompensed in some degree for the ingratitude of the public by the regard and favour of his royal master Charles I. whose attachment to the arts and sciences MEAD. 113 formed a conspicuous part of his character. For the King, with some of the noblest per- sons about the Court, condescended to be spec- tators and witnesses of his experiments; and, indeed, His Majesty took so much interest in his anatomical researches, that, with respect to these very inquiries about the nature of gen- eration, he had received much assistance from the opportunities afforded him of dissecting a vast number of animals, which were killed in the King's favourite diversion of stag-hunt- ing. " Dr. Ent at last succeeded in obtaining the papers; and concludes the account of their in- terview by saying, ' I went from him like an- other Jason in possession of the golden fleece; and when I came home, and perused the pieces singly, I was amazed that so vast a treasure should have been so long hidden.' " Mr. Professor Ward. " You mention the destruction of a former building; pray, where did the College meet prior to the erec- tion of the present edifice in Warwick Lane? Was it not somewhere in the neighbourhood of St. Paul's?" 114 MEAD. Dr. Mead. " I am glad you have asked me that question, for the vicissitudes in the fortunes of our body will gradually be forgot- ten, and it would be very desirable before they are entirely blotted out from our memory, or misrepresented by traditional inaccuracy, that some more public record should be given of them, than that which is contained in our archives. Though as a narrative of events, which has now been continued uninterruptedly for about two centuries *, it would be difficult to find another of fidelity and interest equal to that furnished by the Annals of the Col- lege. " Its very first meetings immediately after its establishment were held in the house of Linacre, called the stone house, Knight-Rider Street, which still be- longs to the College. " The front of that building was appropri- ated to a Library, of the condition or extent of which it may be difficult to form any tol- erable guess after the lapse of so many years. It would of course contain copies of * Now more than 300 years. MEAD 115 The stone house, No. 5, Knight-Rider Street. The armorial ensigns of the College are placed between the two centre windows of the first floor. Their proper blazon is as follows : — Sable, a hand proper, vested argent, issuant out of clouds in chief of the second, rayonee, Or, feeling the pulse of an arm in fesse, proper, issuant from the sinister side of the shield, vested argent; in base a pomegranate between five demi-fleurs-de-lis bordering the edge of the escutcheon, Or. These arms were obtained in 1546. Johanne Barker, Gartero Armorum Rege. 116 MEAD. Linacre's * own works, and there are records of an early date of donations and bequests made to it of books, globes, mathematical instruments, and minerals. " Rather more than forty years had elapsed from the death of Linacre, before permission having been obtained from Queen Elizabeth, dissections began to be performed 1564. within the walls of the College, and, if I am not mistaken, Dr. Lopus was the first Physician appointed to give a public demon- stration. " As soon as the Lumleian Lectures were founded, a spacious Anatomical Thea- 1 583 tre was built, adjoining the house of Linacre, and here Harvey gave his first Course of Lectures. * In the British Museum there are two copies of Lin- acre's translation of the fourteen books of Galen's Methodus Medendi. They are in the finest possible condition^ and are the presentation copies of Henry the Eighth and Cardinal Wolsey. The title of the King's copy is illuminated with the royal arms; that of Wol- sey's is decorated with the Cardinal's hat. On the bind- ing of his Majesty's are the royal arms and motto im- pressed; the dedication to the Cardinal is in manuscript: they are both on spotless vellum. MEAD. 117 " But about the time of the accession of Charles the First, notwithstanding the con- dition of its treasury, the College removed to another spot, and were enabled by the con- tributions of its own Members, assisted by the liberality of two distinguished individuals, to take a house of the Dean and Chapter of St. Paul's, at the bottom of Amen Corner. The lease of these premises was afterwards, from time to time renewed, a botanical gar- den adjoining was planted, and an Anato- mical Theatre built, which last was rendered not only commodious, but even orna- 1641. mental, by the bequest of one of our Fellows *. " The part of the house not actually re- quired for the College meetings, was let to one of its members, upon certain conditions, one of which was that he should maintain the garden handsomely; and, small as it was, the rent paid by this occupant was the only per- manent revenue at that time accruing to the College; for the fees of admission were of course uncertain. * Dr. Alexander Read gave, by will, £100 to orna- ment the Anatomical Theatre. 118 MEAD. " In the calamities and troubles of the civil wars, it was impossible for the College not to be involved, and when the Parliament, by an ordinance of the two Houses, imposed the heaviest and most un- usual taxes, seizing, wherever they had power, upon the revenues of the King's party, they were reduced to the greatest distress. On the City of London alone, besides an imposition of the five and twentieth part of every man's substance, a weekly assessment was levied of <£l 0,000, of which the portion allotted to the College was £5 per week. In consequence of these exactions they became much em- barrassed, were for a time unable to pay the rent due to St. Paul's, and to add to their distress, when it seemed to be the intention of many leaders in Parliament to admit of no established religion, their premises were con- demned, as part of the property of the church, to be sold by public auction. To prevent their falling into the hands of any illiberal proprietor, Dr. Harney became the purchaser of the house and garden, which two 1649. . years afterwards he gave in perpetuity MEAD. 119 to his colleagues. This he did most oppor- tunely, since the design then entertained by the great Harvey of building a Museum in the College Garden might otherwise have been frustrated. This generous project was an- nounced at one of the meetings, in the follow- ing modest manner: — " ' If (said the President*) I can procure one that will build us a library and a reposi- tory for simples and rarities, such an one as shall be suitable and honourable to the Col- lege, will you assent to have it done or no, and give me leave, and such others as I shall desire, to be the designers and overlookers of the work, both for conveniency and orna- ment ?' " The College, as might be expected, as- sented most willingly to so liberal a proposal, and voted a statue, bearing the following in- scription on its pedestal, to be placed in their Hall, in honour of Harvey, who was the per- son alluded to in the speech of the Presi- dent : — * Dr. Prujean. 120 MEAD. GuLIELMO HARVEIO VlRO MoNUMENTIS SUIS IMMORTALI Hoc insuper Collegium Medicorum Londinense Posuit Qui enim Sanguinis Motum ut ET Animalibus ortum DEDIT MERUIT ESSE Stator Perpetuus The building was now begun, and finished the following year, and when the Fellows had all met on the 2d of February, the doors of the Museum being thrown open, the munificent old man, for he w,as now nearly eighty years old, in the most benevolent manner, and wishing all prosperity to the Republic of Medicine, presented at once the Mansion and all its valuable contents to the College *. He then laid down the office * In March, 1823, the late Earl of Winchilsea pre- sented to the College some anatomical preparations which belonged to his ancestor Dr. Harvey; for the niece of Harvey was married to the Lord Chancellor Nottingham, of whom the late Earl was the direct descendant, and possessed his property. At Burleigh on the Hill, where these curious preparations had been carefully kept, is a fine picture of the illustrious physician. Lord Winchil- MEAD. 121 of Professor of Anatomy and Surgery, which he had hitherto held; when Glisson was sea, in presenting them to the College of Physicians, ex- pressed a hope that these specimens of the scientific re- searches of Harvey might be deemed worthy of their acceptance, and thought that they could nowhere be so well placed as in the hands of that learned body, of which he had been so distinguished a member. The preparations themselves consist of six tables or boards, upon which are spread the different nerves and blood- vessels, carefully dissected out of the body: in one of them the semi-lunar valves of the aorta are distinctly to be seen. When Harvey delivered his Lumleian Lec- tures, he may frequently have exhibited these prepara- tions, and by their help explained some points of his new doctrine of the circulation of the blood. They were most probably made by Harvey himself; and he might have learned the art in Italy, for he studied at Padua in 1602. A few years afterwards, on his return to England, he was appointed anatomical and surgical lecturer to the College of Physicians, and in 1616, read a course of lectures there, of which the original manuscripts are preserved in the British Museum. In the College of Surgeons are some preparations similar to these of Harvey, which orig- inally belonged to the Museum of the Royal Society, kept at Gresham College. They were the generous gift of John Evelyn, Esquire, who bought them at Padua, where he saw them, with great industry and exactness (according to the best method then used) taken out of the body of a man, and very curiously spread upon four 122 MEAD. appointed to succeed him. The garden, of an irregular form, extended as far as the Old large tables. They were the work of Fabritius Bar- toletus, then Veslingius's assistant there, and afterwards physician to the King of Poland. Vide Catalogue or Description of the natural and artificial Rarities belong- ing to the Royal Society, etc. By Nehemiah Grew, 1681. Since the time of Harvey, the method of preserving different parts of the body has undergone many changes, and much improvement; and the history of the art would be a subj ect of curious investigation. In the Philosophical Transactions for May 7, 1666, Mr. Boyle mentions a method he had invented of pre- serving or embalming the embryo of a chick in a glass filled with spirit of wine, to which he sometimes added a little sal armoniack, as he observed it never coagulated the spirit of wine. Ruysch, the professor at Amsterdam, if not the dis- coverer of the use of injections, for the display of vas- cular and other structure, contributed, together with the suggestions of De Graaf and Swammerdam, by his own ingenuity and industry, to introduce that important practice among anatomists. His museum became ulti- mately the most magnificent that any private individual had ever, at that time, accumulated, and was the resort of visitors of every description. Generals, ambassadors, princes, and even kings, were happy in the opportunity of visiting it. It was purchased in 1717, by the Czar MEAD. 123 Bailey to the west, and towards the south reached to the Church of St. Martin, Ludgate, and the Museum of Harvey must have stood very near to the spot upon which Stationers Hall has since been built. It consisted of an elegantly furnished convocation room, and a library filled with choice books and surgical instruments. Every patron of learning has- tened to enrich this edifice ; the Marquis 1655. of Dorchester gave <£100, for the pur- chase of books; the famous Selden * left by Peter the Great, for thirty thousand florins, and sent to Petersburg. Dr. Frank Nicholls, who married a daughter of Mead's, was the inventor of corroded anatomical preparations. He was at one time professor of anatomy at Oxford, and author of a treatise De Anima Medicd. * Selden, styled by Grotius, the " glory of the English nation," died about this time, and is thus noticed by Harney in his Bustorum aliquot Reliquiae. " Johannes Seldenus J. C. Qui res a memoria remo- tissimas revocare mortalibus in memoriam semper studuit; Ipsus omnium oblivisci morte coactus est." — 1 Dec. 1654. This may serve as a specimen of the epigrammatic style of this curious work, which is generally character- ized by great good nature, though occasionally the author 124 MEAD. will some curious oriental MSS. relating to physic, and Elias Ashmole, with other bene- factors, presented us with various scarce and valuable volumes. In the Museum of Harvey were deposited the curiosities of the College, and here also were affixed honorary tablets to the memory of those who had deserved well of the community. The generous Harney was not forgotten, and his kind intervention in support of the declining fortunes of the College was thus recorded in marble. 6 de xatpos oH-ug, Balduino Hammo Med. Doctori, Balduini (in Mos- corum aula Juvenili aetate Archiatri) filio, Socio suo, ac ante annos aliquot opportunuo imprimis Benefactori, hoc Marmor (illius animo oblata statua acceptius) Dedicat. Societas An. mdclviii. " The Museum of Harvey, besides medical books, contained Treatises on Geometry, Geography, Astronomy, Music, Optics, Nat- indulges in a vein of sarcasm; as, for example, when speaking of one of his contemporaries, he describes him as — " Syphar hominis ; nee facie minus quam arte Hip- pocraticus." MEAD. 125 ural History, and Travels, and was under the following regulations: — It was to be open on Fridays, from two till five o'clock in the sum- mer, but only till four in the winter season; also during all meetings of the College and whenever else the Custos being at leisure should choose to be present; but no books were allowed to be taken out. The old li- brary room was henceforth appropriated to the Lectures, and the first public meeting of the College (in novo Triclinio) was held in March. Here also, as in a sort of state apartment, it was the custom to re- ceive distinguished and illustrious visitors: for it was not uncommon in those days for the highest personages in the kingdom to attend our Lectures. When Charles the Second con- descended to be present at the anatomical preelections of Dr. Ent, at the conclusion of the Lecture, the royal party retiring from the Theatre, was received in the Museum of Harvey, and on this occasion His Majesty was graciously pleased to confer the honour of knighthood upon the lec- turer. " This event took place the year before the 126 MEAD. fire of London, which, while it destroyed al- most the whole of the City, consumed our Col- lege, and the greatest part of our Library *." The mention of this memorable event oc- casioned a pause in the conversation, and one of our guests, not of the profession, but who, like all persons of an inquisitive turn of mind, was fond of medical subjects, begged to ask Dr. Mead a question connected with that great catastrophe. This is a kind of curiosity that has often struck me as something very amus- ing; to be sure there can be no considerations * One hundred and twelve folio books were saved fromi the flames. About ten years before this calamity, the College of Physicians had been enriched by the will of Sir Theodore Mayerne, who left his Library to them. This prosperous physician, who enjoyed the singular honour of having been physician to four kings, viz. Henry IV. of France, James I. Charles I. and Charles II. of England, died very rich. It is said he left be- hind him £ 10,000 more than RadclifFe. He was a man of singular address, and distinguished for his knowledge of chemistry and natural philosophy. The famous enamel painter Petitot, when in England, was introduced by Mayerne to Charles I. and was indebted also to him for many valuable hints as to the principal colours to be used for enamel, and the best means of vitrifying them. MEAD. 127 more interesting to all mankind than those which relate to the various conditions of health and disease; but it is astonishing to see the avidity with which people of cultivated under- standings listen to the details of professional lore (provided they be not couched in terms too technical), and how much more easily they are satisfied with explanations, and convinced by specious arguments, than the v ere adepti themselves. " I beg your pardon," said this gentleman to my master, " for interrupting your history of the College, but the mention of the great fire of London unavoidably suggests somehow or other the idea of the plague, from the visi- tations of which we have been free ever since the occurrence of that dreadful conflagration. How do you connect, Doctor, the fire of Lon- don with the disappearance of the plague; in short, what effect has the one had upon the other? The subject of the plague occupied your pen some three years ago, and I should like to hear your opinion upon this matter." Dr. Mead. " The fire began, as you know, upon the 2nd of September, and con- 128 MEAD. sumed about one-fifth of the town of London, burning an extent of about two miles 1666. . . , . _. m length, and one in breadth. But it was the wealthiest and the best part of the town that was destroyed; and it is even said, that had it not been for the opposition of some tenacious and avaricious men, aldermen par- ticularly, who would not permit their houses to be blown up, in order to make a wide gap, the conflagration might have been stopped al- most at its first breaking out. But this was thought too great a sacrifice, and the devour- ing element continued its ravages uncon- trolled. A strong east wind drove the flames impetuously forward; the sky was like the top of a burning oven, and the light of the fire was seen for forty miles round about for many nights. The stones of St. Paul's are repre- sented as flying like granados, and the very pavements of the streets glowing with fiery redness; it was not till noon on the third day, nor till the fire had threatened to cross over towaids the residence of the Court itself at Whitehall, that it was stopped, coming no farther westward than the Temple, nor to- wards the north than the entrance of Smith- MEAD. 129 field. Thus, you see, it spared the Borough, Wapping, Smithfield, and some other of the quarters and suburbs of the city, inhabited by the poorest classes, and consequently the abode of filth and wretchedness. The notion therefore advanced by some that the improve- ments in the rebuilding of the metropolis have been the cause of the disappearance of the plague is evidently unfounded. Besides, I may mention to you, that Bristol, the only town in England, except London, which had formerly much foreign trade, though it has been purified by no fire, has nevertheless re- mained equally free from that disease. On the other hand, dysentery and intermittents, two diseases which we all look upon 'as aris- ing from filth and moisture, increased after the fire. Take my word for it, it is quaran- tine alone, and not any increased cleanliness on the part of the inhabitants, that has kept out the plague." — Dr. Mead then returned to his history of the College, and mentioned that after the fire, on application being made to the Judges who were appointed to settle the dif- ferences which unavoidably arose out of that great national calamity, a new lease was ob- 130 MEAD. tained from the Dean and Chapter of St. Paul's — the College undertaking to rebuild the premises. This scheme how- ever was never carried into effect; the lease was resigned, and on the ground where once stood our College, three fair houses were erected, which are now the seats of the Resi- * Old College. "Warwick Lane. MEAD. 131 dentiaries of St. Paul's. In this interval the meetings of the Fellows were generally held at the house of the President; when shortly- after a piece of ground having been purchased in Warwick Lane, our present College was begun to be built, in four years was completed, and was opened, as it would appear, r 1674. without any particular ceremony, on the 25th of February, under the presidency of Sir George Ent, the physician, of whose visit to the immortal Harvey, Dr. Freind gave us a short time ago so interesting an account. " In concluding this sketch of the various fortunes of our body, I beg only to remind you, that according to the custom of the early ages in England, Physicians united the cleri- cal character with the medical, and being thus learned in Physic and Divinity, were not un- frequently called in to administer the com- forts of both professions. But if, in more modern times, the alliance of the two facul- ties has ceased to exist in the persons of their professors, it is still amusing to observe the continuance of the affinity of locality, if I may so term it, for you cannot cross from the house of Linacre, to the spot where our present Col- 132 MEAD. lege stands, and thence to the site of our sec- ond building, without being struck with the sanctity of the ground. On your right you leave the magnificent structure of St. Paul's, and traversing Creed Lane, Ave Maria Lane, Paternoster Row, you finally reach Amen Corner. All these places are within a stone's throw of one another; whether the spirit of innovation, and the change of fashion, may at any future period overcome the genius loci, re- mains to be proved. I have often heard it observed, that though it is convenient to some of us, who live towards the east, yet upon the whole, it is a pity the College was built so near Newgate Prison, and in so obscure a hole; a fault in placing most of our public buildings and churches in the City, which is to be attri- buted to the avarice of some few men, and to His Majesty Charles the Second not over- ruling it when it was in his power, after the dreadful conflagration." The library of Dr. Mead never witnesseed a more brilliant assembly than this; at least the conversation which I have endeavoured to relate made a great impression upon me. MEAD. 133 I do not mean, as was said before, to dwell upon the details of the private practice of Dr. Mead; for, to tell the truth, I have long been (to use one of our new-fangled French words) rather blase on the topic of medical cases. How, indeed, can it be otherwise with me, who have seen five generations of physi- cians; and must, therefore, have infinitely more experience than any doctor who ever existed? One hundred and thirty years have elapsed since I first became connected with physic; for I am almost coeval with the Col- * Interior of Mead's Library; from an engraving in the British Museum. 134 MEAD. lege in Warwick Lane, having made my first appearance fifteen years only after the com- pletion of that building; and can only be said to have completely retired from the bustle of practice within the last two or three years. With the usual appearance of the symptoms of diseases, the ordinary remedies prescribed, and the common topics of consolation and ad- vice, I soon became, even from the very com- mencement of my career, very familiar; it was therefore only by some very extraordinary case indeed, or by attending some very re- markable patient, that I felt much interested. Of the latter description was the illness of that great and good man Sir Isaac Newton. In 1726, early in the month of March, Mr. Conduitt called upon my master, and carried him, together with Mr. Cheselden *, to Ken- * This eminent surgeon and anatomist was chosen Fellow of the Royal Society at the early age of twenty- three years; and soon justified their choice by a variety of curious and useful communications. He was chief surgeon of St. Thomas's Hospital; was also consulting surgeon of St. George's Hospital and the Westminster Infirmary, and had the honour of being appointed prin- cipal surgeon to Queen Caroline, by whom he was highly esteemed. He was much distinguished for his skill as a MEAD. 135 sington, where Sir Isaac had shortly before taken a house for the benefit of his health. It was my lot often to be in company with the eminent surgeon whose name I have now mentioned; for the public seemed universally to have adopted the sentiment of the popular poet of the day: " I'll try what Mead and Cheselden advise." Pope. Consequently, in most complicated cases of importance, requiring the united skill and at- lithotomist, and added also greatly to his reputation by couching a lad of nearly fourteen years of age, who was either born blind, or had lost his sight so early as to have no recollection of ever having seen. The observations made by the patient, after obtaining the blessing of sight, are singularly curious, and have been much reasoned upon by several writers on vision. Surgery is much indebted to Cheselden for the simplicity which he introduced into it. In his own practice he was guided by consummate skill, was perfectly master of his hand, fruitful in re- sources, prepared for all events, operating with remark- able dexterity and coolness. He was, in the strict sense of the term, a great surgeon ; and, being a man of singular candour and humanity, and fond of the polite arts, was honoured by the friendship and acquaintance of men of genius and taste. 136 MEAD. tendance of a physician and surgeon, these two celebrated practitioners were called in to consultation. On our first interview, it was pronounced that the illness of Sir Isaac arose from stone in the bladder, and no hopes were given of his recovery; and yet, to look upon the great philosopher, though now in his eighty-fifth year, he had the bloom and colour of a young man, had never worn spectacles, nor lost more than one tooth during his whole life. Besides being blessed with a very happy and vigorous constitution, he had been very temperate in his diet, though we did not learn that he had ever observed any regimen. He was of mid- dle stature, and at this time plump in his per- son; had a very lively and piercing eye, a comely and gracious aspect, and a fine head of hair, as white as silver, without any bald- ness, and when his peruke was off, he had truly a most venerable appearance. On inquiry we found, that for some years before his present illness, he had suffered so much from the same disorder, that he had put down his chariot, and had gone out always in a chair; had left off dining abroad, or with much company at home. MEAD. 137 He ate little flesh; lived chiefly upon broth, vegetables, and fruit, of which latter he always partook very heartily. Notwithstanding his present infirmities had been gradually in- creasing upon him, nothing could induce him to absent himself entirely from town, and he had continued to go occasionally to the Mint, although his nephew had for the last year transacted the business there for him. It ap- peared that on the last day of the preceding month he had gone to town, in order to be present at a meeting of the Royal Society: on the next day Mr. Conduitt told us that he had seen him, and thought he had not observed him in better health for many years; that Sir Isaac was sensible of it himself, for that he had told him, smiling, that he had slept the Sunday before, from eleven at night to eight in the morning, without waking; but that the great fatigue he had endured in going to the Society, in making and receiving visits, had brought on his old complaint violently upon him. He had returned to Kensington on the Saturday following. This was the statement we received ; and we found him suffering great pain. But though the drops of sweat ran 138 MEAD. down from his face with anguish, he never complained, or cried out, or showed the least signs of peevishness or impatience. On the contrary, during the short intervals between these violent fits of torture, he smiled, and talked with my master with his usual cheer- fulness. On Wednesday, the fifteenth of March, he seemed a little better; and some faint hopes were entertained of his recovery. On Saturday, the eighteenth, he read the newspapers, and held a pretty long discourse with Dr. Mead, and had all his senses perfect ; but at six o'clock on that evening he became insensible, and remained so during the whole of Sunday; and died on Monday, the twentieth, between one and two o'clock in the morning. To find a successor worthy of filling the chair of science, which Sir Isaac Newton had occupied for twenty-four years, was impos- sible; nor is it at any time an easy matter to select one able to perform all the duties of that distinguished station, and to fulfil the ex- pectations and satisfy the claims of the pub- lic. Even to draw the beau ideal of such a one would be difficult. Perhaps he should be MEAD. 139 a man of literary and scientific attainments, and who, though not a labourer in the field of science himself, is so well acquainted with the history and progress of natural knowledge, as to be capable of judging of the value and im- portance of the contributions of others. Pos- sessed of discrimination and tact in the selec- tion of a council, which would be candid enough to aid him in the difficult task of ap- preciating the merit of others, he should him- self be a man of fortune and character suffi- cient to be above the temptation of making his high office subservient to the purposes of pri- vate advancement, or the gratification of self- ish ambition. To these solid advantages, he should certainly add such an acquaintance with at least one foreign language, as to be able in a becoming manner to do the honours of sci- ence to the distinguished strangers who, in their visits to this country, are likely to be recommended to his care. To find an indi- vidual uniting in his own person all these quali- ties is difficult, perhaps impossible; but it may be said, without fear of contradiction, that the study of medicine is likely to have be- stowed a greater number of these attainments, 140 MEAD. than the discipline to which the mind is sub- ject in the pursuit of any other profession. Among the very founders of the Royal So- ciety, we find the names of many distinguished Physicians, as Ent, Glisson, Merret, Willis, Croone, Needham, Whistler; but the honour was reserved for Sir Hans Sloane to be the first Medical President. He had been chosen its Secretary, in 1693, when he revived the publication of the Transactions, which had been for some years suspended: the first act of his Presidency was to make a present of 100 guineas to the Society, and of a bust of their founder, Charles II. He continued in that office fourteen years, and did not resign the chair till the age of eighty: how fit he was to preside over the interests of science must appear from what has already been said of him: and if I might be allowed to anticipate some fifty years, and allude to another Phy- sician who was raised to the same dignity, there will be no reason to blush for the repu- tation of physic. Sir John Pringle was elected President of the Royal Society in 1772; in which office he continued only six years ; but if the volumes of MEAD. 141 Statue of Sir Hans Sloane, by Rysbrach, in the Apothecaries' Garden, Chelsea. 142 MEAD. Transactions, published during that time, be examined, they will be found to contain many- memorable papers: among others, Dr. Maske- lyne's experiments at Schehallien, with Dr. Hutton's deductions from them — The experi- ments of Sir G. Shuckburgh Evelyn and of General Roy to establish correct formulas for measuring heights by the barometer — The re- port of the Committee to determine the proper method of graduating thermometers — Experiments to ascertain the freezing point of mercury. Pringle was the first President who made a set speech on the delivery of the Copley Medals, and his discourses, which were made on rather celebrated occasions, embrace many topics of interest, and show his acquaint- ance with the history of philosophy. They were six in number, the four first of which were, To Priestley, for his Paper on different kinds of Air. To Walsh, for his Experiments on Elec- tricity. To Maskelyne, for his Observations on Gravitation. To Captain Cook, for his Paper on the MEAD. 143 Prevention of Scurvy amongst his Crew, dur- ing his voyage round the world. But I beg pardon for this digression, and must return to my master. On the accession of George the Second, Dr. Mead was made one of the royal physicians, and was for many years engaged in the constant hurry of an ex- tensive and successful practice. By his sin- gular humanity and goodness of heart he con- quered even envy itself; and it was acknowl- edged by all who knew him, that few princes have shown themselves equally generous and liberal in promoting science, and encouraging learned men. He threw open his gallery in the morning for the benefit of students in painting and sculpture; and was in the habit of even lending the best of his pictures to artists to copy. If any literary work was going on, he contributed all in his power to its perfection. For instance, he accommo- dated the learned Dr. Zachary Grey with the loan of his original picture of Butler, the au- thor of Hudibras, (by Mr. Soest, a famous Dutch painter), for the use of the engraver. He constantly kept in his pay a number of artists and scholars, and scarcely a curious un- 144 MEAD. dertaking appeared during the period of his success, that did not find a patron in Mead. Knowing that Mr. Carte (who was accused of high treason, and for whose apprehension a thousand pounds had been offered) had fled to Paris, resided there under the borrowed name of Phillips, and was employed in col- lecting materials for an English translation of Thuanus, my master perceived that his plan might be enlarged; and satisfying Mr. Carte for the pains he had already taken (pretio haud eociguo, as our librarian Mr. Hocker used to say), he employed Mr. Buckley to complete the work. In the first French edi- tion, passages offensive to the nobility of that nation had been omitted; but these were now restored, and a splendid and complete edition printed at Mead's expense. He was also one of the first subscribers to the Foundling Hospital; that noble institu- tion, which will for ever endear the name of Captain Coram to this country. Guy, the wealthy citizen, was also persuaded by my master to lay out his immense fortune in build- ing that hospital in the Borough which bears his name. MEAD. 145 With respect to science, no discovery was made in which he did not take a lively interest. In the year 1746, the experiments tending to illustrate the nature and properties of elec- tricity were made by Mr. afterwards Sir Wil- liam Watson; and he was present on a re- markable occasion, to witness the effects of the Leyden phial, then newly invented. It was in the house of the ingenious philosopher whose name has just been mentioned, in Al- dersgate Street; and here, amongst a large concourse of people, I saw the Duke of Cum- berland, recently returned from Scotland, take the shock with the point of the sword with which he had fought the battle of Cul- loden. Two or three years after this I witnessed the famous experiments made on the Thames and at Shooter's-hill, in the presence of the President and several of the Fellows of the Royal Society; in one of which the electrical circuit was made to extend four miles, and the result of the experiment was, that the velocity of electricity seemed to be instan- taneous. The hospitality of Mead was unbounded; 146 MEAD. and consequently his housekeeping expenses were very great: for, not content with the re- ception of his own friends and acquaintances, he kept also a very handsome second table, to which persons of inferior quality were invited. The consequence of this was, that notwith- standing the considerable gains derived from his profession (for several years he made be- tween £5000 and £6000, and during one year he received £7000), he did not die so rich as might have been expected. The total amount left at his death, including the receipts of the sale of his library, pictures, statues, &c. (which were between £15,000 and £16,000) was about £50,000: but this sum was ma- terially diminished by the payment of his debts. With respect to his manner of living, when not engaged at home, he generally spent his evenings at Batson's Coffee-House; and in the forenoons, apothecaries used to come to him, at Tom's, near Covent Garden, with written or verbal reports of cases, for which he prescribed without seeing the patient, and took half -guinea fees. The last work he published, which was in MEAD. 147 1751, was entitled Medical Precepts and Cau- tions; in which, with great candour and sim- plicity, he enumerated all the discoveries that long practice and experience had opened to him concerning diseases and their cures; and concluded with many salutary directions for preserving the body and mind perfect and entire to a good old age. This he attained himself; and preserved till within three years of his death his intellectual powers in a state of perfection. Then he became very corpu- lent, and his faculties were visibly impaired. But his kindness of heart never deserted him. I shall never forget a piece of insolence on the part of one of his servants, who doubtless presumed on his master's known good nature and forgiving disposition. Dr. Watson was sitting with Mead in his library, when the latter wishing to read something, looked about for his spectacles, for his eyesight had become very bad; and not readily finding them, asked his servant for them: upon which the man gave them to him with great rudeness, saying at the time, " You are always losing your things." How I longed to have knocked the fellow down for his brutality! 148 MEAD. Dr. Mead died on the 16th of February, 1754, in his eighty-first year, and was buried in the Temple Church. After his death, it was said of him, that of all physicians who had ever flourished, he gained the most, spent the most, and enjoyed the highest fame during his lifetime, not only in his own but in foreign countries. ASKEW. CHAPTER III. Dr. Askew had been in his youth a great traveller; at least he was so considered in those days, for he had been absent from Eng- land three years, and had, during that time, visited Hungary, and resided at Athens and Constantinople. To the latter place he had accompanied Sir James Porter, then ambassa- dor to the Porte. In consequence of these peregrinations, he was regarded on his return to his native country as no ordinary person, 150 ASKEW. but one who had enjoyed most unusual ad- vantages, and very rare opportunities of ac- quiring knowledge. This will perhaps hardly be credited at the present moment, when it is scarcely possible to turn the comer of a street without meeting an Englishman recently ar- rived, either from the borders of the Dead Sea, the cataracts of the Nile, or the ruins of Palmyra. Interviews with the Beys and Pashas of the empire of Mahomet have now-a- days succeeded to the usual presentations at the courts of the Continent; and the camel, the firman, and the Tartar, have been sub- stituted for the ordinary facilities of the poste, the passports, and couriers of the beaten roads of civilized Europe. Nor is this spirit of en- terprise confined to the gentlemen of Eng- land, but pervades alike the softer sex. One lady of rank and great talent has taken up her permanent abode at the convent of Mar Elias, on Mount Lebanon; another has ac- companied her husband and family of young children, nurse-maids and all, across the dreary desert, from Cairo to Jerusalem; while a third, of still more adventurous spirit, has climbed, by the help of a ladder of ropes, to the sum- ASKEW. 151 mit of Pompey's pillar. A few years only have elapsed since an English lady of fashion was confined at Athens, gave to her infant son the name of Atticus, and, when sufficiently re- covered, resumed with her husband her jour- ney through the enchanting scenery of Greece ; the child occupying one side of a pair of pan- niers, while a favourite dog reposed on the other. But these prodigies were reserved for modern days. One of the immediate results of the travels of Dr. Askew was the excellent opportunity it afforded him of gratifying the favourite pur- suit for which he was early distinguished, of collecting books, manuscripts, and inscrip- tions. At Paris, on his way home from his eastern expedition, he laid the foundation of his library, which became afterwards so cele- brated: for, in the love of books, he resem- bled Dr. Mead, for whom he entertained a sort of filial veneration, and to whom he had, when a very young man, and while studying physic at the university of Leyden, dedicated his specimen of an edition of JEschylus. At the sale of my late master's library, he had been one of the most distinguished of the 152 ASKEW. emptores literarii, and, even during his life- time, had purchased all his Greek manu- scripts, for which he paid the sum of five hun- dred pounds. Not content with possessing himself as much as possible of his books, statues, and other curiosities, he did all he could to preserve the lineaments, and perpetuate the memory of * Now in the Censor's Room of the College. ASKEW. 153 the person of his deceased friend. For this purpose he procured Roubiliac to make a bust of him, which he presented to the College of Physicians. No one could be better acquainted with the real features of Dr. Mead than myself; and I pronounce this bust of him to be so like, that, whenever it is before me, it suggests the strongest idea of the original; and, indeed, when the marble came home, Dr. Askew was so highly pleased with its execution, that though he had previously agreed with the sculptor for £50, he offered him £100 as the reward of his successful talent; when, to his astonishment, the sordid Frenchman exclaimed it was not enough, and actually sent in a bill for £108. 2s.\ The demand, even to the odd shillings, was paid, and Dr. Askew enclosed the receipt to Hogarth, to produce at the next meeting of artists. My present master never practised any where but in London: but his father, Dr. Adam Askew, was a celebrated physician at Newcastle-upon-Tyne, where he enjoyed a great provincial reputation, and lived to a good old age. With reference to him, a con- 154 ASKEW. versation which occurred at a literary party in the metropolis excited a laugh at the time, and was to the following effect: Some one of the company having remarked that my master, Dr. Askew, looked very ill — but indeed, from his advanced age (whereas he was not then fifty) he could not be expected to last a long time — "Possibly not," replied a gentleman with a smile, " but I dined with his father about a fortnight since at Newcastle, and he appeared to be in perfect health." From the Library of Dr. Mead, in Ormond Street, I had removed but a short distance, and could scarcely be said to be sensible of any change in the scholastic air of my present abode. Our house in Queen Square was crammed full of books. We could dispense with no more. Our passages were full; even our very garrets overflowed; and the wags of the day used to say, that the half of the square itself would have done so, before the book appetite of Dr. Askew would have been satiated. We saw a great deal of company, attracted as well by the abundant luxuries with which my master's table was furnished, as by the ASKEW. 155 classical conversations and learned accounts of curiosities which he had brought with him from his very interesting travels in Greece. — Among the literary people who were most fre- quently there, I may mention Archbishop Markham, Sir William Jones, Dr. Farmer, Demosthenes Taylor, and Dr. Parr. By these distinguished persons Dr. Askew was consid- ered as a scholar of refined taste, sound knowl- edge, and indefatigable research into every thing connected with Grecian and Roman learning. Indeed, from his youth upwards, he had been distinguished for his love of let- ters, and had received the early part of his education under Richard Dawes the critic. His father, on presenting him to the school- master, marked those parts of his back which Dawes, who was celebrated for his unsparing use of the birch, might scourge at his pleasure, excepting only his head from this discipline; and my master was wont to relate with some humour, the terror with which he surveyed for the first time this redoubted pedagogue. As a collector of books Dr. Askew was the first who brought bibliomania into fashion; and no one exhibited his various treasures better than 156 ASKEW. himself. The eager delight with which he produced his rare editions, his large-paper copies, his glistering gems and covetable tomes, would have raised him high in the esti- mation of the Roxburgh Club. Some, in- deed, were of such great rarity, that he would not suffer them to be touched, but would show them to his visitors through the glass cases of the cabinets of his Library, or, standing on a ladder, would himself read aloud different por- tions of these inestimable volumes *. As specimens of his wealth in this line, I may enumerate — His Platonis Opera, apud Aldum, 2 vol. fol. 1513, Edit Prin. on spotless vellum; the ink of which was of the finest lustre, and the whole typographical arrangement a master-piece of printing. His Boccacio, la Teseide, Ferar. 1475, Prima Edizione, which was then considered an unique copy, and was sold after his death for £85. What it would have fetched under the sceptre of Mr. Evans cannot even be con- jectured! * His Micyllus de Re Metrica was one which he prized highly. ASKEW. 157 His Ciceronis Opera omnia, Oliveti, 9 vol. quarto, 1740; charta maxima. These were amongst many others which I cannot now specify, but which were then re- garded as rare, magnificent, giants, imperial, atlas, elephant, princes of editions!! As no one had enjoyed greater opportuni- ties, possessed more sufficient means to gratify his taste, or had an acuter descrimination, the Bibliotheca Askeviana was well known to all, both at home and abroad, who were in the least eminent for bibliographical research. And as he had expressed a wish that his books might be unreservedly submitted to sale after his decease, the public became ultimately bene- fited by his pursuits, and many a collection was afterwards enriched by an Exemplar Askevianum. The sale (apud S. Baker et G. Leigh, in vico dicto York Street, Covent Garden, Februar. 1775) occupied twenty days. But the library of my present master was not, as I have said before, the only attraction which our house afforded: to many of his guests, the recital of his adventures during his travels abroad was a constant source of 158 ASKEW. * This model is about 12 inches high, is of unbaked potters' clay, and is now in the possession of Sir Lucas Pepys, Bart., whose lady is the daughter of Dr. Askew. ASKEW. 159 amusement; and we saw most foreigners who came to London. Dr. Askew had been in the East, and so vague and magnificent was the opinion formed at that time of an oriental traveller, that I verily believe he was supposed to have been able to speak all the languages of that quarter of the globe. It was from some such notion as this that they brought to him a Chinese, by name Chequa, who (however im- perfect their oral communication might be) seemed so grateful for the attention and kind- ness he had received, that he requested before his departure from England to be permitted to make a model of the Doctor in his robes; which being readily granted, we sat to the stranger: and this is the specimen of his in- genuity, rendered with Chinese fidelity. From what has been said of the pursuits of Dr. Askew, it may be inferred that much of his time was employed in his library, and dedi- cated to the conversation of literary men; but he was not entirely inattentive to professional engagements, and I took of course no small in- terest in watching the progress of medicine, and becoming acquainted with the rising and eminent physicians of the day. Amongst 160 ASKEW. others, there was one who had settled in Lon- don two years before Dr. Askew, and who rapidly got into great business, which he fol- lowed with unremitting attention above thirty years, for he lived many years after the death of the former. Previous to his coming to town, Dr. Heberden had been established at Cambridge, where he gave Lectures on the Materia Medica for about ten years: among his pupils were students who afterwards greatly distinguished themselves, as Sir George Baker, Dr. Gisborne, and Dr. Glynn; the latter of whom was a character long known and valued in Cambridge, both for his virtues and his eccentricities. Of his method of lec- turing, a specimen is preserved in his Essay on Mithridatium and Theriaca, published in 1745, three years before he quitted the university. Treating of this famous medi- cine, which had recently been expunged from our public dispensatory, Dr. Heberden proves, that the only poisons known to the ancients were hemlock, monk's-hood, and those of venomous beasts; and that to these few they knew of no antidotes. That the farrago called after the celebrated King of Pontus, which, ASKEW. 161 in the time of Celsus, consisted of thirty-eight simples, had changed its composition every hundred years, and that therefore what had been for so many ages called Mithridatium, was quite different from the true medicine found in the cabinet of that Prince. This, he states, was a very trivial one, composed of twenty leaves of rue, one grain of salt, two nuts, and two dried figs; and he infers that, even supposing Mithridates had ever used the compound (which is doubtful), his not being able to despatch himself was less owing to the strength of his antidote than to the weakness of his poison. The first accounts of subtle poisons that might be concealed under the stone of a seal or ring, as well as the, stories of poisons by vapours arising from perfumed gloves and letters, he pronounces to be evi- dently the idle inventions of ignorance and superstition. The learning and good sense which char- acterize the whole of this little Essay, will enable the reader to form a judgment of the manner in which he conveyed instruction to his class, and of the loss which the university must have suffered by his removal; but he would 162 ASKEW. probably have settled in London earlier than he actually did, had the encouragement held out to him, to come to the metropolis, not been most unfairly kept from his knowledge. The circumstances attending this want of good faith will be best explained by the following letter from Sir Edward Hulse to Dr. Heber- den, then residing at Cambridge, and Dr. H.'s reply: — " Baldwyn, July 14, 1748. " Dear Sir, " I shall be very glad to embrace any op- portunity of showing you how sincerely I wish your welfare; and I assure you, when I desired to dispose you to come to London, I did unfeignedly mean to serve you, knowing you to be capable of answering any recommendation your friends could give you. then sent me word, you had no in- clination to leave the University. What shall I say to you now? Even what I said to , who at the persuasion of his friends was afterwards inclined to come himself, and try his fortune here, viz. That when I left London I had, as far as I could, recommended ASKEW. 163 Dr. Shaw to my business: so it stands now, except that Dr. Shaw has too much business, more than he can possibly do, upon which ac- count I have endeavoured to assist Dr. Taylor, who came from Newark. He is greatly sup- ported by some noble families, and has already wonderfully succeeded. I have set before you the difficulties that I lie under, of recom- mending any body at present. I don't in- tend to flatter you, when I say, I make no doubt you will be able to support yourself by your own merit ; and as far as shall be consist- ent with honour, jointly with my power, which is now very little, you may depend upon the friendship of, "Sir, " Your most affectionate " humble servant, "E. Htjlse. " P.S. — Since the writing of this, I am cer- tainly informed that Dr. Shaw is gone over to Hanover with the Duchess of Newcastle. I believe you never will have a fairer oppor- tunity of settling in this town than the pres- ent." 164 ASKEW. Dr. Heberden's answer. " August 30, 1748. " I take the opportunity of returning my thanks by Mr. H., for your most obliging let- ter. No one can be ignorant that your assist- ance and recommendation must be of the highest advantage to any person who was be- ginning the practice of physic in London; and I am persuaded they would at any time have determined me to fix there, though I had otherwise no such intention. But I never was rightly informed that I had such a valuable opportunity in my power. By what accident or mistake it happened, I do not know, but the person you mention never acquainted me with it at all, nor indeed any one else with authority from you. I had only heard accidentally, that you had expressed yourself with great civility, on a supposition of my removing to London. There was no reason, when I first heard such reports, to imagine that they amounted to any thing more than your good wishes. As soon as I could believe there was the least proba- bility of your intending to assist me with your interest, I immediately took the liberty of ASKEW. 165 writing to you. I must reckon it among my greatest misfortunes, that this application came too late: though I shall always think myself under the same obligations to you, as if I had enjoyed the benefit of your kind in- tentions. My best acknowledgments are due for the assurances of your disposition to assist me still, where your other engagements have not put it out of your power ; and it is with the highest satisfaction that I find myself pos- sessed of a place in your friendship. I pro- pose seeing London some time in October, in order to consult with some friends about the advisableness of my settling there, when I hope to have the pleasure of paying my re- spects to you." He settled in London the following Christ- mas. The name of the person alluded to in Sir Edward Hulse's letter does not appear, for it was effectually erased from the origi- nal letter, though it shows something indica- tive of a superior mind to be told, that Dr. Heberden afterwards lived on terms of friend- ship with the author of so base a transaction. Not long after he came to reside in town, he 166 ASKEW. met Dr. Mead in consultation at the Duke of Leeds', and observed his faculties to be so im- paired, that he then determined within him- self, that if he ever lived to the same age of seventy-eight, he would give up practice. And this resolution he strictly adhered to, say- ing that people's friends were not forward to tell them of their decay, and that he would rather retire from business several years too soon, than follow it one hour too long. " Plutarch," said he, " has told us that the life of a vestal virgin was divided into three portions; in the first of which she learned the duties of her profession, in the second she practised them, and in the third she taught them to others." This, he maintained, was no bad model for the life of a physician; and when he had passed through the two first of these periods, he addressed himself diligently to the work of teaching others. The motto prefixed to his commentaries was expressive of this his favourite maxim — npmv xai xdfivsiv obxiri Suvafievos, touto to BiftAiov eypcupa. But while in the enjoyment of health, he lived ASKEW. 167 much with scholars and men of science, among whom may be reckoned Gray, Bryant, Wray, Cavendish, Hurd, Kennicott, Lowth, Jenyns, Tyrwhitt, Jortin, and most of the distin- guished men of his time. Of the amusements of this literary coterie, take this as an example. Mr. Stuart, best known by the name of Athenian Stuart, having presented Dr. Heb- erden with a tea-chest made of olive wood from Athens, Mr. Tyrwhitt, who soon after dined with him, inspired by so classical a sub- ject, sent him the next day the following copy of verses. In Attic fields, by famed Ilissus' flood, The sacred tree of Pallas once I stood. Now torn from thence, with graceful emblems drest, For Mira's tea I form a polish'd chest. Athens, farewell! no longer I repine For my Socratic shade and patroness divine. Sir William Jones * afterwards rendered * Translated by Sir William Jones. IIa?,Xa8og tjv nors devhpov en 'EtXcffeoto fiesdpotq Kapizyt ayaXXofievov xatXnzaprj (pexadi, Ts/JLve pap^ 6 yXuTzrr)? xat ano^eae, vuvde 8savou JUL ^ Ql< f> >^e-