COLUMBIA LIBRARIES OFFSITE HEALTH SCIENCES STANDARD HX64146812 RC61 .W24 The student's guide RECAP Columbia ^ntbn^tt|) tntI)e(Citp0tUttogork (taiU^ of Phgstrtana anb ^urg^anH G. L. PEABODY THE STUDE^S'T'S GUIDE TO CLINICAL MEDICINE AND CASE-TAKING BY FKAXCIS WARXER, M.D. Lond., F.RC.P. ASSISTANT PHYSICIAN, LECTURER ON BOTANY, AND LATE MEDICAL REGISTRAR TO THE LONDON HOSriTAL; LATE PHYSICIAN TO THE EAST LONDON HOSriTAL iOR CHILDREN EXAMINER TO THE UNIVERSITY OF ABERDEEN SECOND EDITION PHILADELPHIA P. BLAKISTON, SON & CO. 1012, WALXUT STREET 1885 INTKODUCTIOX TO SECOND EDITION FuRTHEE experience gained since the publication of the former edition, has shown that students commencing clinical work need to be taught to think, and reason for themselves, as well as to observe. It is hoped that the plan of this work tends to give such training if properly used. The size of this work has not been increased, but new material has been added, and corrections have been made in accordance with the advances of clinical medicine, especially in the chapter on diseases of the nerve-system. A special scheme for taking notes of children has been added, and the index has been made more complete. F. W. 24, Harley Street, W. December, 1884. miKODUCTIOX TO FIRST EDITION. DuEiNG the three years that I held the office of Medical Registrar to the London Hospital, I saw that the student, on commencing his duties as clinical clerk, required some guide as to the method of arranging the history of his case, and the facts observed. A card of "instructions for case-taking" was provided, almost similar to that given at page xi. It was further evident that with each case the student needed, when taking his cases, to be told what special points to note iu the history, and what special points to look to under each of the heads of the "instructions." Further, zeal was much stimulated in the thoughtful student by telling him why these special points should be enquired for, and their presence or absence noted. Such points, with regard to the more commonly recurring diseases, have been put together, and presented in the following pages. The object has been to provide, in a small space, a guide for the student to use at the bedside, when wanting to know what to look for, and what to note. Pathology and treatment are not touched upon, and for this reason, independent of the general incompleteness of this little work, the student is recommended to read, in some text-book, all about his case in hand. Much attention has been given to the special conditions met with in disturbance and disease of the nervous system. vi INTRODUCTION. To encourage enquiry as to the origin of disease, the principal causes in each case are indicated under the heading "causation," which will usually be found on the left-hand page, sometimes on the right-hand ; thus the student may find his enquiries directed on reasonable grounds. As to the scheme of the work, as far as possible the facts indicated as specially to be observed are arranged under the ordinary heads of a case on the left-hand page, and on the corresponding right-hand page are given explanations, characters of the special disease, or points of interest in its natm'al history, etc. This plan could not in all cases be adhered to, and general convenience and the necessities of printing had then to take precedence of the original scheme. Names printed in the text in thick type are heads of chapters contained in the work, which may be found on reference to the index. Thus, in taking a case of fever, look for "Signs of Fever," and if Vomiting or Jaundice be present look up these heads by means of the index. F. W. 24, Harley Street, W. 1881. CONTENTS. TAVrV. Instructions for Case-taking .... xi — xiii Additional Instructions for Children's Cases xiv, xv Table Showing Healthy Development of an Infant xvi General Diseases — Class I. Common bad Hygienic Conditions — Signs of Fever — Table of the Specific Fevers : Enteric Fever ; Typhus ; Scarlet Fever ; Measles ; Variola ; Varicella — Erysipelas — Diphtheria — Pyaemia — Puerperal Fever — Ague — Hooping-cough — Syphilis, inherited ; Syphilis, acquired 1 — 17 General Diseases — Class IL Signs of Defective Development — Anaemia ; Pernicious Anaemia — Cancer — Rickets— Emaciation — (Edema or Anasarca — Amyloid Degeneration — Scrofulosis : General Miliary Tuberculosis — Table of Differences and Resem- blances between Enteric Fever and Tuberculosis — Diabetes Mellitus — Addison's Disease — Purpura — De- velopmental Defects — Senile Degeneration . , .19 — 33 Arthritic Diseases. Arthritis — Rheumatoid Arthritis — Table of Joints for Description — Rheumatism ; Gqaiorrhceal Rheumatism — Gout 34-39 Vni CONTEXTS. Diseases of the Nervous System. PAGE General Conditions of the Xervous System — Intel- ligence — Speech — Sleep — Head-pain — Headache — Vomiting — Coma — Vertigo — Delirium — Typhoid State — Paralysis — -Tendon Reflexes — Skin Reflexes — Table of Diagnosis of Functional from Organic Paralysis — Elec- tric Tests — Convulsion — Spasm — Laryngismus — Tremor - Athetosis — Motor Power — Sensation — Muscular Anses* thesia — Special Senses — Cranial Nerves — Bell's Paralysis of the Face — Brain Disease — Ophthalmoscopic Appear- ances — Pupils — Signs of Spinal Cord Disease — Minor Para- lyses : Progressive Muscular Atroph}' ; Pseudo-hyper- trophic Paralysis ; Paralysis of Extensors of Forearm ; Cross Paralysis ; Bulbar Paralysis ; Paralysis of Face — Neuralgia : Sciatica ; Intercostal Neuralgia — Hemiplegia - — Chorea — Table of Diagnosis of Chorea from Sclerosis — Hysteria ; Epilepsy ; Table of Diagnosis of Epilepsy from Hysteria — Cerebral Tumour — Cerebral Meningitis — Chronic Hydrocephalus — Table of Diagnosis of Hydro- cephalus from Rickets— Alcoholism- —Acute Alcoholism — Delirium Tremens — Insanity— General Paralysis of the lasane— Paralysis Agitans — Sclerosis of the Cord — Te- tailus — Locomotor Ataxy— Infantile Paralysis — Graves' Disease — Plumbism — Diphtheritic Paralysis — Herpes Zoster 40—101 Diseases of the Vascular System. Physical Examination of the Heart : Pulse ; Passive Congestion — Important Anastomoses — Table of Signs of Valvular Lesions, Mitral Regurgitation and Obstruc- tion ; Aortic Regurgitation and Obstruction ; Hj'per- trophy and Dilatation of the Heart — Cardiac Displace- ments — Valvular Disease — Heart Disease — Table of Diagnosis of Functional from Organic Palpitation — Angina Pectoris — Pericarditis — Congenital Defects of the Heart — Tricuspid Regurgitation — Thoracic Aneurism — Disease of Vessels .,,,,,,. 102—123 CONTENTS. Diseases of the Respieatory System. PAGE Clinical Regions of tlie Chest — Physical Examination of the Chest — Auscultation — Cough — Sputum — Hemo- ptysis ; Table of Diagnosis of Heemoptysis from Hiema- temesis — -Dyspnoea — Pulmonary (Edema — Contraction of Lung — Solidification of Lung — Table of Diagnosis of Pneumonia from Pleuritic Effusion — Pleurisy; Em- pyema ; Hydrothorax — Phthisis — Pneumonia — Em- physema — Bronchitis — Asthma — Laryngeal Diseases. 124 — 149 Diseases of the Digestive System. Signs of Digestive Functions : Appetite — Intestinal Worms — Examination of the Mouth and Throat : Tongue ; Palate ; Tonsils ; Pharynx ; Teeth ; Gums — Diarrhcea — Vomiting — Acute Abdominal Pain — Dys- phagia — Htematemesis — Meltena — Obstruction of the Bowels — Gastric Ulcer — Typhlitis — Abdominal Cancer : Cancer of Stomach ; Cancer of Intestines — Ulceration of Bowels : Dysentery ; Tubercular Ulceration — Abdominal Tumours : Ovarian ; Kidney ; Spleen ; Abdominal Aneurism; Tumours arising from the Pelvis — Faecal Accumulations — Phantom Tumour — Intussusception — Examination of Abdomen — Fluid in Peritoneum — Dia- gnosis of Ovarian Tumour from Ascites — Peritonitis . 150 — 173 Diseases of the Liver. Jaundice ; Table of Causation ; Jaundice from Ob- struction or Independent of Obstruction — Large Livers : Lardaceous, Fatty, Hydatid — Cancer of the Liver — Small Livers — Acute Yellow Atrophy — Cirrhosis of the Liver — Syphilitic Disease of the Liver — Gall-Stones ; Biliary Colic— Hydatid of Liver .... 174—18^ CONTEXTS. Diseases or the Up.inary System. PAGE Bii^t's Disease — Uraemia — AlbtuaiiLiiria — Hsma- tmia — ^Paroxysmal Haematuria — Acute Briglit's Disease — GiamilaT Contracted Eidneys — Fatty Kidneys — Amy- loid and Laige White Eidneys — Briglit's Disease, Acute or Chroiiic — ^Disrases of the Bladder — Renal Calculus ; Benal Colic — ^Description of Urine ; Examination of the Deposit, ChemieaUj and Microscopically — Normal Con- stitn^Lts of the Urine ; Abnormal Constituents j Albu- men, Sngar, Bile, Leucine, Tyrosine — ^Urinarj'^ Calculi —Mnrexide Test for Uric Acid . . . . 184—203 SlGXS OF PBEGlfAJfCY — COESrCIDENT SiGXS AXD Symptoms ....... 204, 205 I>-DEX . 206—211 INSTRUCTIO]S"S FOR CASE-TAKING. I. Enter name, age, occupation, address, date of admission to hospital, and date at which the notes were taken, II. State what the patient complains of, as far as possible using his own words. With children say what the friends complain of, III. Family History. — Number and condition of health of those living. Ages and diseases of those dead. Specially enquire as to points in the inheritance bearing on the case and its causation. Personal History. — Habits, occupations, residences, previous illnesses and diseases. Indications of scrofula, gout, rickets, syphilis, etc. Give dates. History of Present Illness. — Date and manner of com- mencement ; date when last at work. Order of the occurrence of symptoms, with date. Indicate the day of illness on the temperature chart. In taking this history look up the causation and course of the disease as given in the text. Probable causes. IV. Present Condition. — General condition. Intelligence; mental state ; sleep ; complaints of pain, etc. Nutrition ; emaciation ; anaemia ; oedema ; complexion ; any specially obvious abnormal condition or source of distress, etc. Position of patient in bed ; orthopnoea ; dorsal decubitus ; etc. Pulse = ; Temperature = ; Respirations = ; Weight = . Xll INSTRrCTIOXS FOE CASE-TAKING. Lymphatic Glands in neck, axilla, groins ; size, hardness, mobility ; tendency to suppuration. Locomotor System. — State of bones, muscles, joints, scars, nodes. Skin, dry or moist ; bed-sores. Y. l^ervous System. — General Condition. Intelligence ; sleep ; speech. Vertigo ; head-pain. Delirium ; paralysis ; convulsion ; tremor ; coma, etc. Motor Foiver. — Ability to stand or work ; movements of extremities ; gait in walking ; co-ordination of limbs. Eeflezes, Sensibility. — Tactile sensibility of skin ; sensibility to beat and cold, also to pricking. Anaesthesia ; hyper- ffistbesia ; dyssesthesia. Special senses. Cranial Nerves. — Movements of eyes, tongue, palate, face. State of pupils. Ophthalmoscopic examination. YI. Vascular System. — Pulse, frequency and other characters ; condition of the vessels, especially the arteries. Cyanosis. Heart ; palpate, auscultate, percuss. ^STote precordial dulness if normal. Palpitation, pain or signs of heart disease. YII. Respiratory System, — Dyspnoea, frequency and charac- ters of the respiratory movements. Cough ; expectoration ; hsemoptysis. Physical Exariiination. — -Inspection; palpation; percus- sion ; auscultation. Signs of bulging or contraction of chest or solidification of lungs, etc. Larynx. YIII. Digestive System. — Tongue; teeth; throat. Appetite ; thirst. Vomiting ; haematemesis ; melaena. State of bowels ; tenesmus ; griping ; piles. Fulness or pain after food .; flatulence ; pyrosis ; colic or other disturbance. Abdominal pain or tenderness, INSTP.rCTIOXS FOR CASE-TAKING. Xlll ii ye /'.— Size and general characters as determined by percussion and palpation : whether tender or not, Jaundice. Spleen. — Size as determined by percussion and pal- pation. Abdomen. — Physical examination. Whether tender, dis- tended, retracted. Ascites. Tumour. IX. Urinary System. — TJrine, quantity, colour, reaction, Sp. gr. Albumen, bile, sugar. Deposit, its general, chemical, and microscopical characters. Frequency of micturition ; if accompanied by pain ; heematuria. X. Generative System. — Menstraation : frec|uency ; duration ; quantity increased or otherwise ; whether painful ; other discharges. Conditions of uterus and pelvic organs. XI. Treatment. — Prescriptions and diet, etc., should be entered in the notes, and all alterations noted, with the dates. XII. Diagnosis. — Should enumerate the principal disease, secondary lesions, complications and specially important conditions, symptoms or points in the treatment. ADDITIONAL INSTRUCTIONS FOR CHILDREN'S CASES. II. State complaints made concerning the child, or obvious conditions of disease. III. Family History. — Number and condition of health of those living. Ages and diseases of those dead. Specially enquire as to the inheritance bearing on the case. History of mother's health during the intra-uterine life of the child. Note any miscarriages, Avith dates. Personal History. — Whether healthy at birth ; how brought up ; if suckled ; if farinaceous food has been used. Previous illnesses, and diseases. IV. Present Condition. — General condition: plumpness; skin elastic, clear or muddy looking, with aged appearance. Condition of Development. — Anaemic ; hsemorrhagic flea bites ; sweating. Bones, feel them all while the child is stripped. Signs of syphilis, rickets, etc. Note Avarmth of the limbs ; whether the child sheds tears in crying. T. = ; P. = ; R. = ; "W. = . Signs of defective development. V. Nervous System. — General condition. Note the amount of movement of limbs, hands, and feet, or whether this is absent. Intelligence, as indicated by movements of face and eyes directed towards objects noticed. Sleep ; making noises ; consciousness ; exhaustion ; coma. Paralysis ; examine each limb. Spasm ; tremor ; contraction. ADDITIONAL INSTRUCTIONS FOR CHILDREN S CASEUS. XV Motor Power. — Reflex action on tickling hands, putting finger in mouth, etc. Playfulness ; ability to laugh. Power over large joints, small joints, movements of fingers, etc. Cranial Nerves. — Movements of eyes and face. Head. — Its shape and circumference. Fontanelle is patent, prominent, or depressed. State of other sutures. Ophthalmoscope. VI. Vascular System. — Pulse : frequency and character. Cyanosis. Heart : palpate, percuss, auscultate. VII. Respiratory System. — Dyspnoea; frequency of respiratory movements ; laryngeal stridor, spasm, or obstruction. Warmth or coldness of breath. Cough. Physical PIxamination. — Inspection ; signs of collapse at bases and clavicular regions. [To examine back, let child be held leaning over nurse's shoulder.] Palpation ; rhonchi may sometimes be felt. Percussion. Aus- cultation. In children, and especially infants, the feeling of resistance of lung, or its elasticity beneath the finger struck, gives valuable information as to its consolidation or clearness. VIII. Digestive System, — Tongue, lips, throat ; state of den- tition. Appetite and liking for food ; how it is fed. Vomiting. State of bowels. Abdomen : whether full or empty ; palpate ; note size of liver and spleen. State of umbilicus. Pain after food ; flatulence ; abdominal ten- derness ; griping of bowels. Test milk used for cream and acidity. ' In examining an infant, it is necessary to determine if it be well developed. See Developmental Defects. The child should be weighed, and the circumference of the head, at its longest, should be measured. XVI ADDITIONAL IX.STIiUCTlON.S FOR CHILDREN" S CASES. Tlw fulloicing Table is for a licalthy well-developed infant of good-class : — Infant at birth -weighs six to ten pounds ; head circum- ference, 11 "15 — 12'5 inches. S« I Points indicating Stage and Progress of M s i Development. I. II. III. lbs. j ins. j 7tolOj 14 "5 I Power to suck; regular succession of feeding and sleeping ; hand reflex. 11 "0 15*25 ' Hair in eyelashes and eyebrows ; may be occasional strabismus. 13-5 16-5 Capability of shedding tears ; no strabismus. IV. 15*0 I 17"0 Constant movement while awake. V. j 15*5 I 17"0 Turning head to a light or sound. t ! VI. I 16*0 1 17 "25 Pi.ecognizing objects, as mother, nurse. VII. ! 17*5 j 17"5 Holding object in hand, and carrying it to mouth. VIII. ! 18 "5 ; 17 '75 Various sounds made ; commencing dentition. IX. 19"5 \ IS'O Some power to hold up head Avhen lying do-^^Ti. X. i 19'6 18'25 Holding an object without dropping it. XI. I 19'7 i 18"4 ' Power to transfer object from one hand to the other. j I XII. 20"0 18*5 i Commencing to crawl or stand with assistance. THE STUDENT'S GUIDE TO CLINICAL MEDICINE. GENEKAL DISEASES— CLASS I. Specific diseases caused by semie poison received by tJie patient from without, andj in many cases communicable from one patient to another. COMMON BAD HYGIENIC CONDITIONS. Drawing drinking-water from a cistern over w.c. Overflow pipe from a cistern opening into a sewer or soil-pipe instead of into open air. Drain from a kitchen sink opening direct into a sewer or cess- pit instead of into open air over a drain. Want of proper traps cutting off house-sewer from street-sewer, and each soil-pipe from house-drain. Want of ventilation of house-drains and soil-pipes, with arrangements for access of air into them, and exit of sewer- gas from them, may cause foul smells. 2 CLINICAL MEDICINE AND CASE-TAKING. FEVER, SIGNS OF. General condition. — Temperature raised ; respirations and pulse frequent ; skin diy and hot, or sweating ; rigors ; fever: pains ; acMng in back and limbs ; prostration of muscular power ; face presents depressed look. P, = ; T. = ; R. = . Mode of onset. — Sudden, with rigors, headache, pains in back and limbs ; gradual, with anorexia and thirst, loss of strength. Digestion. — Anorexia ; thirst ; bowels confined or relaxed ; describe the motions passed. Tongue furred, dry, or moist ; papillse may be enlarged. State of gums ; teeth. Throat ; tonsils. Vomiting, Spleen may be enlarged. lAver, see Jaundice. Vascular system. — Pulse frequent, soft, may be dicrotous and intermittent. Heart's action quick ; note strength of impulse and first sound. Tendency to capillary con- gestion. Respiratory system. — Respirations frequent ; tendency to con- gestion of the lungs. Pulmonary (Edema; Bronchitis; Pneumonia; Pleurisy. Nervous system. — Mental condition, see general condition of Nervous System. Sleep ; Headache ; Delirium ; Typhoid State. Urine. — Scanty. Sp. gi". high. Commonly a deposit of Lithates. It may be jaundiced or albuminous. Urea may be in excess. Look for rash and the characters of the Specific Fevers ; local and general complications. GENEKAL DISEASES — GLASS I, FEVER, SIGNS OF. General condition. — An exanthematous fever does not often recur in the same individual. The date and mode of onset are important, so also whether sudden or gradual, with or without rigors. Digestion. — Sordes and accumulations of mucus may occur on lips and teeth. Note any inability to take food or to swallow. Jaundice is common in relapsing fever, and may be present with Pyaemia, Typhus, etc. Vascular system, see Pericarditis. — Danger may arise from failure of heart's action, and weakness of the circulation. Note complexion of the lips and face, fulness and tension of pulse. Pkespiratory system. — Note fulness or shallowness of respirations. Examine lungs fi'equently, even if there be no symptoms of their disturbance. Note cough or Expectoration. Nervous system. — Mental condition disturbed ; delirium not necessarily of bad prognosis. Hyperpyrexia and ady- namia dangerous. Urine. — Albuminuria may be temporary, or it may lead to chronic Bright' s disease. Look for causation ; cold, contagion in case of specific fevers, bad hygienic conditions. Causation. — Contagion ; concurrent or previous illness in same house ; smells from sewers ; water supply ; date of exposure to contagion ; infection by clothes. CLINICAL MEDICINE AND CASE-TAKING, SPECIFIC ERUPTIVE FEVERS. DAYS OF FEVER AND RASH. ENTERIC FEVER.— Onset gradual ; temperature slowly rising, falling at end of 3rd or in the 4tli week with exacer- bations at night. Small oval hypersemic spots on abdomen in successive cro^^s in 2nd and early in 3rd weeks. SIGNS AND SYMPTOMS. Abdominal pain and ten- derness; gurgling over cae- cum. Bowels usually relaxed. Spleen large. Temperatm'e may be excessive. Occasion- ally sudamina. Bronchitis common. Bowels may be constipated. TYPHUS FEVER. — Onset severe, with rigors and pains in back and limbs. Temperature rises rapidly 4 to 5 days, falling about 14th day. Mul- berry-coloured maculae, at first slightly raised, then dull mottling, appear in 1st week, disappear end of 2nd week. SCARLET FEVER.— Onset rather sudden, with chilliness. Temperature rising rapidly. Rash 2nd day on neck, chest, and trunk, extending to the limbs ; minute red points, quickly becoming a diffused erythema. Rash passes off about 7th day, leaving desquamation of skin. Tem- perature falls about same time. Headache and nervous symptoms prominent ; de- lirium usual. Much tendency to heart failure and hypo- static congestions. Bron- chitis. Bowels not usually relaxed. Tongue thickly coated, with enlarged red papillae protruding ; tip quickly be- coming red. Fauces inflamed ; tonsillitis. Desquamation specially seen on hands and feet. Occasionally there is no rash. Delirium. GENEEAL DISEASES — CLASS I. SPECIFIC ERUPTIVE FEVERS. COMPLICATIONS. ENTERIC FEVER.— Signs of heart failure. Delirium. Typhoid State. Hypostatic congestion of lungs. Albu- minuria. Hsemorrliage from bowels ; perforation of intes- tine. Profuse sweating, see Tuberculosis. Phlebitis. Se- quential abscesses. Tendency to relapses of fever and other symptoms. TYPHUS FEVER.— Active Deli- rium passing into the Typhoid State. Hypostatic pneu- monia. Albuminuria. "Weak action of ventricles, and very soft pulse. CAUSATION. Impure water. Sewer gas. Probably not con- tagious, but by the evacua- tions. Note occupation ; residence, and its hygienic condition ; sources of milk supply. Contagious from the sick to the healthy. Its spread is favoured by over-crowding, bad hygienic conditions, and starvation. SCARLET FEVER.— Albumi- nuria and ansemia with ana- sarca from Acute Bright' s Disease. Inflammation of the throat may be excessive, with ulceration. Arthritis. Scarla- tinal rheumatism. Inflam- mation of the middle ear. Glandular abscess in neck. Hyperpyrexia. Pleurisy or empyema rather than pneu- monia. Convulsions. Scarlet Fever. — Rheumatic symp- toms often commence at the beginning of the 2nd week with swelling in sheaths of tendons, and some redness, tenderness, and moisture of skin. Subsequently stiff" neck not uncommon. Highly infectious, especi- ally through the dust of the skin. The type varies greatly in diff'erent epi- demics ; in some, greater tendency to complications or death. CLINICAL MEDICINE AND CASE-TAKING. SPECIFIC FEVERS. DAYS OF FEVER AND RASH. MEASLES. — Rash appears about 4th day ; begins on face, spreading to the trunk aud limbs. Fine red points, becoming flat and forming crescentic patches. Tempera- ture begins to fall two or three days after rash appears. SIGNS AND SYMPTOMS. Specially common in chil- dren. Onset with chills or rigors. Sleepiness. Catarrh ; conjunctivee watery ; coryza. If rash is full, desquamation mav follow. VARIOLA.— Rash appears 3rd day, fii'st on forehead as red papules, soon becoming vesi- cles, feeling hard as shot ; 5th day they become umbili- cated and purulent ; 8 th day pustules mature, then scab. Temperature rises rapidly ; falls as rash appears ; secon- dary fever vith the suppura- tion. Incubation after inocula- tion, 7 days ; after infection, 12 days. Onset with great pains in limbs and back. Rigors. Vomiting'. The pustules may become con- fluent or remain distinct. VARICELLA.— With onset, small red spots appear on trunk, face, scalp, becoming resides, but these are not cellular or umbilicated ; they crust. Temperature not high. Very little constitutional disturbance. GENEEAL DISEASES — CLASS I. SPECIFIC FEVERS. COMPLICATIONS. MEASLES.— Mostly in respi- ratory system. Bronchitis. Acute broncho - pneumonia, which, may become chronic. Laryngitis may be severe ; it precedes the rash. There may be vomiting and diarrhoea. Delirium. Rarely cutaneous haemorrhages. Occasionally Albuminuria. CAUSATION. Very infectious, especially during the eruptive stage. VARIOLA. — Mucous surfaces frequently affected, especially conjunctivae, throat, nose. Bronchitis ; Pneumonia ; Pleurisy ; diarrhoea ; Albu- minuria ; abscesses. Cuta- neous haemorrhages and bleeding from the mucous surfaces, Typhoid State. Very infectious. Inocul- able by pus of vesicles, also by scabs. VARICELLA.— Ifone are usual. Infectious. CLOnCAI. MEDIdSTE AlO) CASE-TAKING. ERYSIPELAS. Tj., -:i:: :: ::^ /;-'_rr mncli swollen, red, i:o"iis , "rViiti^ei ZL.^ i_.i:^:r.5 of the i nfl aTned part rimed or diffiiaed. 3^::^ :-.-r-- Tesieles or buBsB. ::; ralaiged tymphalic glands. I^ote signs and mi of Fever. CemfiiMa&m&. — CeUnliiis ; alisoess; gangvene. Ddirinn.; the Ijrplioid State; ADbaniKiiria; FBeuuniiB; FletoiBy; FUeUtis; FeiietiriitiB; tedeaiia of lazynx; infamina- tioM of £aiiD^u Diaxdioea. ; relapses of the disease. DIPEIHEEIA, Q<- :; :Lr : 2.7:t:.: . i';.!:?;" to swallow, strengtli of voiee, Djspaicea, 3 '-it.::. : : body. P. = ; T. = ; R.= . "Rya. ^ 2£:-j.iii and Throat for redness and sweDing of Uit :i: r- soft palate, nvnla, pharynx; paibGlies of meii- : i :. : : - ^r^idation, wMtisli or greyish, oflbeaa mnlltiple : i:.t"_i. i^i-t id ay be peeled off, leaving smrfeffle of imac:'i.? iiTi_::i"-:-r raw, but not ex<^vated. Zxi-iir.-^ Ir; = : It -"_•:-, r:;::-^. .-'.ir. is Hinder the Jaw. Note igeal Bisease. - T ,. . iMrymt^ooA sym^^wis. — CommeiMaiig with a short eongh, and -■_i:lt li:^:"i'— ' ::" ^'r. h^^i:sL2 : "':reathii!g noisy, stridnlous, — :1 1, iir'illi-v-: ;:. l::.^- : : : ^-.i : weak voice; straggling : : ::riT'_ l... - i::;:;;^!- : :'...t~: c-oHapsing ; pnlse weak; i^It ':'_:.:-':. : rrTiri-^Lnes cold ; sweating. Note if trache- iTiii"'.' .: ■: :_i_ 11 ::_-::. or not. — Faenumia; Flemisy; Mbaadnnxia; adynamia il^raae on oomjnnctiva and ^in ; Faralysis. GENERAL DISEASES — CLASS I. ERYSIPELAS. An acute febrile disease characterized by local diflFiised inflamma- tion of skin and cellular tissue with bullse and vesiculation. Idiopathic erysipelas usually attacks the face, commenc- ing about the eye. Causation. — Epidemic and endemic causes. Exposure to cold, and bad hygienic conditions ; contagion. It may follow injury or operation. Those once attacked by the disease are liable to recurrence. DIPHTHERIA. A febrile contagious disease, characterized by the formation of membranous exudations on the fauces and respiratory mucous membrane, frequently obstructing the larynx, often attacking the mucous membrane of the nose and causing an acrid discharge. It is asthenic in its course, and attended by gi'eat debility, frequently proving fatal through Laryngeal Obstruction or by pneumonia. The period of incubation is various. It may commence with lassitude, febrile disturbance, sore -throat ; or those pre- liminary symptoms may be absent, laryngeal stridor being the first symptom noticed. Sometimes swelling of the glands under the jaw first attracts attention. There may be membrane in the larynx, and none on the fauces. There is less pain on attempting to swallow than with quinsy. Fever not prominent ; rarely runs high. When paralysis follows, it is usually after convalescence. Causation. — Communicable from the diseased to the healthy by secretion of mouth, vomits, expired air. Bad water ; sewer gas, and bad hygienic conditions. Most common in children. It may be epidemic or endemic. 10 CLINICAL MEDICINE AND CASE-TAKING. PYEMIA. Examine the body all over for any wound, local inflammation, or suppuration. A very slight wound may produce the disease, e.g., a thorn under the nail, etc. See Signs of Fever and General Condition of the Nervous System, prostration. Coma, Typhoid State. Causation. — Suppui'ation connected with diseased bone ; whit- low ; Phlebitis ; softening clots ; ulceration from tertiary syphilis ; Periostitis. Occasionally it is secondary to internal suppuration or ulceration, e.g., enteric fever, gastric ulcer, abscess of kidney, etc. ComjMcations. — Occasionally a cutaneous erythema. Jaundice, without signs of obsti-uction ; Albuminuria ; haemorrhages in skin or from mucous membranes. Low forms of inflammation ; Pericarditis ; Pneumonia ; Pleurisy ; em- pyema ; Peritonitis. PUERPERAL FEVER. GeTieral condition. — General signs of Fever. Patient usually assumes the dorsal decubitus. There is much tendency to adynamia and the Typhoid State, with sweating and Delirium. Ahdoriicii. — Usually distended and tympanitic ; bowels often costive. There may be local tenderness over the uterus or in either iliac fossa. Genito-iirinary system. — Xote pain or difiiculty on micturition or defsecation. Lochial discharge, its amount, if off'ensive ; any clots or pieces of placenta or membranes passed. Albuminuria. Breasts, if milk is secreted ; condition of the glands, tenderness. Causation. — Epidemic at periods. Endemic in a house or hospital ; due to inoculation by nurse or attendant, e.g., from. a case of erysipelas, or another puerperal case. Infection with an acute specific fever, e.g., scarlet fever. Local septic poisoning from metiitis, decomposing clobs, or portions of placenta. Bad hygienic conditions. GENERAL DISEASES — CLASS I. 11 PYJEMIA. Usually commences by an insidious onset, or with chilliness or rigors, and fever with sweating and great prostration. It is characterized by the formation of multiple abscesses, and arthritis with a tendency to suppuration in or around the joints. The tendency is to death by exhaustion, the patient passing into the typhoid state, or by its com- plications. It may be mistaken for Eheumatism or Enteric Fever, or ma}^ be confounded with broncho- pneumonia, which often accompanies it. Any source of suppuration may lead to the disease, whether the pus be discharged, as from an open abscess, or retained in deep parts, as from periostitis and acute necrosis. PUERPERAL FEVER. An acute febrile disease, probably of septic origin, following shortly after confinement, and incommunicable to those not in the puerperal state. The onset occurs about 2nd or 3rd day after confinement, with chilliness or rigors, and the signs- of Fever. Usually this is attended with scanty and offensive uterine discharges. The secretion of milk is often suspended, but what is formed does not hurt the infant. Complications. — Pleurisy. Empyema. Pneumonia. Pericarditis. Albuminuria. Pelvic cellulitis or parametritis. Peritonitis. Mammary abscess. Phlebitis, or phlegmasia dolens. Arthritis. Varieties of Fever. — It may be specially characterized by Peritonitis ; by pelvic cellulitis ; metritis, with much abdominal pain and tenderness. Simple fever, with alteration of secretions, but no other local manifestations ; the fever tending to exhaustion, adynamia, and the Typhoid State. 12 CLINICAL MEDICINE AND CASE-TAKING. AGUE. Enquire as to the periodicity of the paroxysms. Describe ar attack, giving, if possible, the duration of the stages. Note conditions of health in the inter-paroxysmal period. Paroxysms may occur daily — quotidian ; with one-day interval — tertian ; mth two-days interval — quartan. Note general appearance and condition ; whether Anaemia or cachexia. Examine optic discs : sometimes hsemorrhages are seen in the retina. Urine. T. = ; R. = ; P. = . Also note condition of Spleen and liver. General condition of the Nervous System. ComjMcoMons mul Sequelce. — Enlargement of spleen and occasionally liver ; digestive organs disturbed. Dysentery ; jaundice ; Anaemia ; melansemia (pigment granules in blood) ; retinal hemorrhages ; cachexia ; Neuralgia ; brow-ague. Causation. — Endemic, in low and ill-drained districts. Symptoms may follow in a few hours after imbibing the poison, or may be delayed. HOOPING-COUGH. Geiiera.l condition. — State of nutrition ; look for signs of Rickets. P. = ; T. = ; R, = ; W. = , Enquire for signs of catarrh preceding the development of hooping ; simple cough, with expectoration, running at nose, etc. Respiration. — Physical examination of lungs ; the chest, its shape and movements, signs of collapse. Cough ; paroxysms, describe them, their frequency, duration, and mode of subsidence ; note the amount of asphyxia and venous congestion. Complicatimis. — Pulmonary collapse ; specially in cases of Eickets, which usually do badly. Bronchitis and broncho- pneumonia ; Convulsions ; Diarrhoea. Epistaxis ; blood often ejected from mouth. GENERAL DISEASES — CLASS I. 13 AGUE. Characterized by feverish paroxysms, recurring at regular intervals, the patient being well between the paroxysms. Paroxysm. — 1. Cold stage: Lassitude, headache, malaise, chilli- ness, shivering, passing on to rigors, the teeth chattering and limbs trembling ; muscular pains ; epigastric discom- fort ; goose-skin ; face dusky, pinched, shrunken. Pulse small ; respirations quick ; temperature rising rapidly. 2. Hot sta.ge : Rigors and chilliness disappear, succeeded by a comfortable warmth ; face less shrunken. Patient then feels hot ; flushes ; there may be mental excitement. Skin dry and frequently hot ; pulse full and strong ; respirations more rapid. Headache. Temperature rises higher. Urine abundant. 3. Sweating stage : Feeling of heat diminishes ; temperature falls. Skin becomes moist and sweating profuse. Pulse and respiration fall in frequency. Headache passes off. Patient feels easy and sleeps, awaking feeling well. Urine scanty, depositing lithates. Temperature may rise without a developed paroxysm. HOOPING-COUGH. Characterized by paroxysms commencing with a series of expiratory coughs, followed by deep, full inspiration with loud laryngeal spasm. Frequently vomiting and expecto- ration with paroxysms. Child may be comparatively well in intervals. Asphyxia in paroxysms very great ; this may lead to ecchymosis under conjunctiva. Sublingual ulcer often results from stretching the fraenum over the lower incisors during paroxysms. Ejection of blood not a bad symptom. Look for any spasmodic signs, such as Tetanus or chronic spasmodic conditions of muscles of one extremity ; this is almost entirely confined to Rachitic children. Enquire as to a source of contaffion. 14 CLI>:iCAL MEDICINE AND CASE-TAKING. SYPHILIS— Inherited. General condition. — Unhealthy aspect ; dull earthy complexion ; old and shrivelled appearance. Rash on skin ; erythe- matous patches with abrupt margins ; coppery tint. Squamous skin lesions about mouth, chin, limbs, soles of feet. Sometimes a scab or a pustular rash with bullse ; there may be much desquamation. The skin about nates and mouth mostly aifected. Nails may be unhealthy and chippy. Mucous membranes. — Mucous tubercles or condylomata at anus and at angles of the mouth ; diffuse stomatitis ; inflamma- tion of gums and tooth-sacs. Thrush. Discharge from nose, often excoriating the lip ; snuffles. Laryngitis ; voice or cry hoarse. Viscera may be affected : spleen large ; liver. Bmies. — Periostitis may be very extensive, causing much deformity of limbs and thickening of the skull. Skull thick ; forehead prominent ; craniotabes. Swelling of ends of long bones just above epiphyses. Nervous system. — Deafness (nerve disease) and amaurosis more common than with the acquired disease ; palsy of a single nerve less common ; occasionally epilepsy or imbecility. GENERAL DISEASES — CLASS I. .15 SYPHILIS— Inherited. This may lead to deposit of gummata. Eyes. — May be early the seat of iritis, later of keratitis, which occurs towards adult life and is usually symmetrical. There may also be choroiditis. Nose. — Mucous membrane swollen ; this leaves nose sunken and flattened. Occasionally, in severe cases, the skin disease is obvious at birth, but usually child appears perfectly healthy till about six weeks old ; the thrush and the rash, etc., then appear. Marks left in adult. — Bridge of nose sunken in ; linear scars near angles of mouth and about anus. Interstitial keratitis ; iritis ; choroiditis. Prominent forehead* Nerve deafness. — Often only slight and temporary ; in some absolute and permanent. Teeth. — All the incisors may be dwarfed and malformed. The upper central incisors are most reliable, dwarfed, usually narrow and short, with atrophy of the middle lobe, leaving a single broad vertical groove. 16 CLINICAL MEDICINE AND CASE-TAKING. SYPHILIS — Constitutional and Acquired. Stages : — Incubation ; efflorescence ; decline ; relapse ; sequelae. General condition. — Tendency to emaciation ; debility ; vague pains. Anaemia. Look for scar of primary sore. Digestion. — Mucous tubercles of lips ; sores, leaving scars, at angles of mouth. Tongue, Soft Palate, pharynx ; ulceration on tonsils. Superficial and symmetrical ulcers in first stage ; deep, destroying parts, when tertiary ; destruction of these parts. Ulceration and condylomata of anus. Liver, perihepatitis ; gummata. Besjiiration. — Laryngeal Disease with ulceration and tendency to contraction. Lung disease of chronic character. JVervotis system. — Disease of Brain or Spinal Cord. Gummata, forming tumour in brain. Palsy of Cranial Nerves, especially nerve iii. and nerve vi. ; disease of auditory nerve. Iritis ; choroiditis ; retinitis. Meningitis ; pre- disposition to Ataxy. Locomotor system. — Nodes and thickening of bones ; Periostitis. Skin : syphilides, psoriasis, serpiginous tubercular patches, ulcers with ragged edges, etc. Lymphatic glands. — Generally enlarged in neck and groins, without tendency to suppuration. Special phenomena. — Gummatous masses in viscera and skin, etc. Condylomata and mucous patches on mucous membranes, or ulceration with tendency to contracting scars. Disease of testes. GENERAL DISEASES — CLASS I. 17 SYPHILIS* — Constitutional and Acquired. These phenomena may be considered as occurring in the second and third stages. SecoTid stage. — Follows six weeks to two months after inocula- tion. Rash on skin, scattered coppery eruption ; or it may be scaly, papular, pustular, rather on flexor than dorsal aspect. On mucous membranes symmetrical ulcers, tonsils especially, with abrupt edges ; condylomata may form anywhere. Iritis usually symmetrical. Occasionally slight periostitis. Third stage. — Tendency to unsymmetrical ulceration of skin and mucous membranes, with great tendency to relapse. Scars tend to contraction and pigmentation. Tendency to sloughing. Bone disease. — Periostitis, nodes, chronic thickening, destruction of nasal and palatal bones. Gummata may form in any viscus. In liver they may be felt during life ; in brain may cause signs of tumouk ; in skin may lead to extensive sloughing. Arteries often diseased. This may lead to aortic Aneurism, minute arterial aneurisms in brain, and haemorrhage, Thrombosis, and gangrene. * Mr. Hutchinson's Article— Reynolds' "System of Medicine." GENEEAL DISEASES— CLASS II. Diseases often inherited, frequently arising from some internal changes in the patienf s tissues or organs, hut often due to causes acting from ivithout. SIGNS OF DEFECTIVE DEVELOPMENT. Search for accompanying congenital defects of development. Defect of heart ; cleft palate ; deformity of hands or feet ; supernumerary fingers and toes ; epicanthic folds in excess ; unusual shapes of the ears, and asymmetry between the two ears ; coarse or ichthyotic skin ; hair on forehead. Abnormal conditions of head ; size and shape ; fontanelle and sutures, whether open. They are sometimes pre- maturely ossified, and the forehead prow-shaped. Eye : Coloboma ; congenital defect of sight. Undescended testicle ; hydrocele ; hernia. Skin : Coarse, ichthyotic ; deficient in elasticity ; increased areolar tissue ; extremi- ties blue ; chilblains. Description. — But little spontaneous movement ; dirty habits ; fits ; paralysis ; inability to hold head up, to talk or walk. In low-class cases repetitive movements are com- mon, e.g., continuous movement of one arm, purposeless and rhythmical ; absence of intelligence ; not attracted by light or sound. Lungs. — Liability to bronchitis. Nervous system. — Defective in intelligence ; convulsions ; defective motor power ; insuf&cient power of co-ordina- tion. Causation. — Syphilis ; drunkenness in parents ; relationship between the parents. Most common in first member of a family. 20 CLINICAL MEDICINE AND CASE-TAKINQ. ANEMIA. Pallor of skiu and mucous memlDranes, lips, aud conjunctivae. When the fingers are held up to the light the redness of the borders is seen diminished. (Edema of feet ; possibly puffiness of face. ^ Circulation. — Examine arteries and veins in the neck ; condition of heart. See condition of the blood and its microscopical characters. Look for Diseases of Vessels. Breathlessness. Nervous system. — Headache; Neuralgia, especially spinal; intercostal nem-algia ; drowsiness ; mental weakness and irritability ; muscular weakness ; pains in back. Examine optic discs. Me7istrv^Mo7i. — Disordered ; usually lessened, or absent. Look for Pernicious Anaemia, leucocythsemia, enlarged glands, cancer, hsemori'hages from mucous membranes or under skin ; heart disease ; chronic lung disease ; Bright' s Disease. Examine urine. Examine liver and spleen. T. = : P. = : R. = : W. = . PERNICIOUS (Progressive) ANEMIA. Look for general signs of anaemia, and the ordinary causes. See amount of redness of the fingers held before a strong light. Examine optic discs ; there may be retinal haemorrhages. Note condition of the joints and general power of the patient ; also state of digestion. CANCER. Geiural conditio7i. — Anaemia; cachexia; Emaciation; loss of muscular strength. Temperature not raised. Disturbed functimi of ^jar^s affected. — Pressure signs from growth of mass, e.g. — (1) Glands in transverse fissure of liver obstructing the vena portse and causing Ascites, or the duct, causing jaundice ; (2) Mediastinal tumour ; (-3) Pressure on veins, e.g., vena cava or iliac veins ; (4) Intra- cranial tumoui' ; (5) Annular stricture of intestine. GENERAL DISEASES — CLASS II. 21 ANiEMIA. Circulation. — Over jugular vein, especially on the right side, a thrill may be felt with the fingers, particularly in children ; but this does not necessarily indicate anaemia. A con- tinuous humming sound heard, Bruit de Diable, over jugular like wiind among trees, varying with the pressure of the stethoscope. Systolic blowing over the carotid or subclavian artery on very slight pressure. Over the pulmonary (2nd left) costal cartilage a systolic bellows, the second sound being often sharp and accentuated. Heart's action quick ; easily excited to palpitation. Pulse soft and frequent. Causation. — Haemorrhage ; menorrhagia. Sequent to acute disease. Defective hygienic surroundings. Hot rooms. Want of good food regularly taken. Dyspepsia ; chronic gastric disease; Alcoholism; Plumbism; mental exhaus- tion ; fright ; Malaria ; heart disease ; Cancer ; often due to over-long lactation ; general delicacy ; disturbed nights as well as lactation ; re-establishment of menstruation during lactation. Coincident disease ; Bright's disease sequent to pregnancy ; rapid development of phthisis, which was quiescent during pregnancy. PERNICIOUS (Progressive) ANiEMIA. Profound increasing aneemia, accompanied by increasing debility and prostration, tending to death in many cases. Haemorrhages ; spongy gums ; epistaxis ; breathlessness ; palpi- tation on exertion. Fat of the body not absorbed ; the subconj unctival fat yellowish . Excretion of urea diminished . There may be irregular pyrexia. CANCER. Causation. — Hereditary ; declining period of life ; sequent to blows. Organs commonly affected — uterus, mammse, liver, stomach, peritoneum, other abdominal sites, lungs. Secondary deposits. — In liver, from the rectum, sigmoid flexui'e, stomach, etc. In lymphatic glands next to the organ affected. Complications. — Serous effusion ; adjacent inflammations ; thrombus of veins. 22 CLINICAL MEDICINE AND CASE-TAKING. RICKETS. Eaquire as to conditions of feeding ; ability to stand or walk ; age at "wMch walking commenced ; previous health, especially as to symptoms and complications of rickets. Examine bones, head, abdomen. Anaemia. Bo>ie$. — Ribs beaded ; enlargement of ends of ribs at their junction with the cartilages. Sternum thrust forward by the falling in of the ribs at side of chest ; hypochondriac regions depressed. Spine may be bent backwards, but is capable of being sti'aightened on suspending the body, lifting the child by the arms. Shaft of long bones often bent, especially in tibiae if child has walked ; epiphysis enlarged, particularly in radius. Skull may remain patent long after the first year ; the head is large, wide, and flat on the vertex. See diagnosis from Chronic Hydrocephalus. Head may be small and not ill-shapen. Craniotabes, or soft spots viith deficiency of bone, can be felt sometimes in the occipital bone. EMACIATION. History as to probable causation. Emaciation, whether gradual or sudden, or coincident -with other signs of disease. Dis- tribution of the emaciation, especially in children. The emaciation often afiiects the body and extremities more than the head and neck. Examine all the organs and urine. Kote weight of patient, and record it once a week. Specially enquire as to histoiy of phthisis. Look for Anaemia, and the signs of any disease supposed to have pro- duced the emaciation. When a muscle is stinick, e.g., biceps, note its irritability, longitudinal contractions, and ti'ans- verse knotting. Kidritioii indicated by the relation of age, height, weight, etc. W. = . Spare, thin, emaciated, stout, fat, good muscular development, strong, weak. Growth rapid, moderate, slow. GENERAL DISEASES — CLASS II. 23 RICKETS. Thickening and deformity of bones. The child may be fat or ill-nourished. Much tendency to sweating, especially about the head ; throws off the clothes at night ; head much rubbed on the pillow, so that hair is worn from occiput. Dentition late ; the teeth often devoid of enamel — soon decaying. General tenderness, so that child cries on being moved. Late in walking. Late signs : Head large, flat, square ; figure too small in the legs. Complications. — Tendency to catarrh of intestines ; diarrhoea; abdomen large and prominent ; Spleen and liver large. Bronchitis ; collapse of base of lungs. If Hooping-Cough supervenes, it runs an unfavourable course with bronchitis ; Convulsions and Laryngismus. Causation. — Ill-feeding during infancy, especially with farina- ceous food ; intestinal catarrh ; bad hygienic conditions : premature birth. Digestion. — Teeth late in appearing, and often deficient in enamel ; abdomen large, prominent, tympanitic, partly owing to weak condition of its muscles. Nervous system. — Liability to convulsion; laryngismus; tetany, or chronic contraction of muscles of extremities. EMACIATION. Causation. — Chronic lung disease ; Phthisis ; caseous bronchial glands. Cancer. Chronic stomach disease ; Diarrhoea ; Vomiting. Starvation and ill-feeding, especially in infants. Defective hygienic conditions. Senile Degenera- tion. Sequent to acute disease. Fever. Diabetes. General Tuberculosis. Disturbance of the general condition of the Nervous System. In infants often called Marasmus. Look for signs of Congenital Syphilis ; collapse of lungs ; Rickets. See state of skin ; fulness or retraction of abdomen. State of bowels ; con- stipation or chronic diarrhoea. State at birth, if suckled ; how fed, and nature of foods. Thrush. 24 CLINICAL MEDICINE AND CASE-TAKING. (EDEMA OE ANASARCA. Anaemia. Signs of disease of heart or vessels. Look fox Cardiac Dilatation or degeneration. Lungs. — Especially empliysema or phtliisis. Urine.— See signs of Bright's Disease. If anasarca be thought to be due to passive congestion, look for the signs of passive congestion, and note if the oedema lessen or increase •with such other signs ; e.g., note if oedema lessen with the disappearance of pulmonary oedema, etc. If anasarca be due to Bright's disease, note if it lessen with lessening Albuminuria, and increase of the quantity and sp. gr. of the urine. AMYLOID DEGENERATION. Pasty, anaemic appearance. Anasarca. Liver. — Large, firm-edged, uniformly enlarged, smooth. Usually no jaundice or ascites. S^ileen. — Large, firm, smooth. Kidneys. — Urine very albuminous. Anasarca. Intestines. — Diarrhoea. CoALsaMon. — Syphilis. Chronic suppuration. Phthisis, with suppuration of bronchi. Chronic disease of bone, see Scrofula. GENEKAL DISEASEg-^CLASS II. 25 (EDEMA OR ANASARCA. Causation — Obstruction at heart. — Passive (Cardiac) Congestion. Cardiac valvular disease ; failure of the ventiicles ; fatty heart ; dilated right ventricle. Adherent pericardium. Obstruction at lungs. — Emphysema. Chronic bronchitis. Conditions obstructing circulation in one lung, e.g., chronic pleurisy, empyema, collapse of one lung. Local pressure on veins. — Pressure on vena cava or iliac veins in abdomen from enlarged glands, Cancer, Aneurism, pregnancy. Abdominal Tumour, pelvic effusion ; pres- sure from ascites. Pressure on subclavian vein from thoracic aneurism or mediastinal tumour. Changes in blood or vessels. — Bright's Disease. Anaemia ; extreme debility from chronic disease, e.g., cancer, Phthisis, diarrhoea in children, Phlebitis, phlegmasia dolens, varicose veins. SCROFULA. General condition. — W. = ; T. = ; R. = ; P, = . Intelligence dull ; phlegmatic temperament. Coarse, flabby, ungainly children, outlines of body ill-marked. Features plain, complexion pasty. Liable to ophthalmia ; tinea tarsi ; otorrhcBa, eczema, lichen, lupus, chilblains, blue hands. Forehead and back hairy. Respiratory system. — Liability to bronchitis and chronic pneu- monia passing on to Phthisis. Digestive system. — Abdomen full ; liability to diarrhoea. Teeth, no distinctive condition, liable to decay, may be devoid of enamel. Upper lip thick. Gums unhealthy. Tonsils large. Locomotor system. — Bones thick ; joint disease frequent. Skin easily inflamed. Glands enlarged and suppurate, specially in neck. 26 CLINICAL MEDICINE AND CASE-TAKING. GENERAL MILIARY TUBERCULOSIS. General condition. — Look for signs of strumous disease in bones, joints, spine ; enlarged glands ; Emaciation ; state of skin. P. = ; T, = ; R. = . Look for Signs of Fever. Respiratory system. — Signs of Consolidation of Lung or Phthisis ; enlarged bronchial glands ; cough. Digestive system. — Vomiting; state of bowels, see Ulcer ation of Bowels ; ability to take food. Nervous system. — Signs of Meningitis ; signs of Brain Disease. Ophthalmoscopic examination may show optic neuritis or tubercles in choroid. Tubercle in choroid indicates tuberculosis, not meningitis ; optic neuritis with tubercle indicates probable tubercular meningitis. The onset may be insidious, with a previous period of emaciation and lassitude, and after a few days or weeks may be followed by the somewhat sudden onset of a special complication, as Pneumonia ; Meningitis. The general symptoms are mostly prostration, Emaciation, sweating, cough, moderate fever — this may be absent. Some of the complications are usually present, and frequently there are the signs of old strumous disease. The disease tends to death by exhaustion or by complications. The presence of miliary tubercles in the lungs does not necessarily cause any abnormal physical signs. GENERAL DISEASES — CLASS II. 27 ENTERIC FEVER resembles GENERAL MILIARY Diarrhoea from typhoid ulceration of Payer's patches. I. Evening exacerbations of fever, mostly in 3rd or 4th Aveeks. III. Profuse sweating, with great debility and prostra- tion. IV. Bronchitis and pneumonia common complications. V. Emaciation from fever. VI. Mental dulness from fever. TUBERCULOSIS. Diarrhoea from tubercu- lar disease of intestines. Remittent hectic fever common, with caseous lung or glands, etc. Profuse sweating a part of the natural course of the disease. Chronic pneumonia may set up general tuberculosis. Emaciation from tubercu- losis. Commencing Meningitis. DIAGNOSTIC DIFFERENCES. I. Characteristic rash on the abdomen, etc. II. Diarrhoea and abdominal symptoms prominent. III. Spleen often large. IV. Lung symptoms late in appearing. V. Delirium and exhaustion, proportioned to height and duration of fever. VI. Occurs in those previously healthy. VII. Profuse sweating less common. VIII. High fever. IX. History of individual and family healthy. X. Any age. No exanthem. Skin may be erythematous ; or suda- mina. Bowels usually consti- pated. Spleen usually normal size. Lung symptoms appear early. Definite signs of menin- gitis. Usually previous lung disease. Sweating usual. Fever not high. Individual or family scrof- ulous. Usually young. 28 CLINICAL MEDICINE AND CASE-TAKING, DIABETES MELLITITS. General conditimi. — Emaciation; weakness. Skin harsh and dry. Mental aberration ; low spirits. See Nervous System. Digestion. — Appetite gi'eatly increased ; intense thirst. Tongue frequently devoid of epithelium, raw and cracked. Bowels costive ; sometimes diarrhoea. TJrine. — Quantity usually greatly increased ; greenish colour ; high sp. gr. ; sugar abundant. Micturition frequent. Causation. — Most common in males and middle-aged adults ; frequent in phthisical families. Exposure to cold. Alcoholism ; excessive use of sugar ; violent emotional disturbance ; organic Brain Disease ; over mental Avork or anxiety. It may be associated with Gout. ADDISON'S DISEASE. General condition. — Debility, faintness, pigmentation. Antemia. Frequently tubercular tendency. Shallow, feeble breath- ing ; breathlessness, sighing, gasping, especially on any effort. T. = ; usually subnormal. If not compli- cated, no emaciation. Feeble heart action, faintness, pulse thready. Death by asthenia, sudden or preceded by incoherence, delirium, convulsions. Digestion. — Nausea, retching, Vomiting, epigastric pain. Examine buccal mucous membrane and that of lips. Hiccough ; anorexia. Nervous system. — Its general condition. Pains and sleeplessness. Loss of nerve -muscular power ; extreme depression. GENERAL DISEASES — CLASS II. 29 DIABETES MELLITUS. Characterized by excessive tliii'st, excessive hunger, emaciation. Urine saccharine, dense, and greatly increased in quantity, as a constant occurrence. Saccharine urine may be tem- porary, as after a convulsion or administration of chloro- form. Diabetes is the more permanent condition of glycosuria, with constitutional symptoms and a tendency to certain complications ; it usually has a fatal tendency. Onset of symptoms may be insidious or sudden, with nervous disturbance. Sugar may be detected in sweat, tears, saliva. Urine. — The quantity of sugar usually greatest after food. Glucose may temporarily disappear ; so also, not uncom- monly, shortly before death. CoonpUcaticms. — Broncho-pneumonia ; Phthisis ; Pleurisy, Serous inflammation of low type. Head-pain; sudden Coma ; cataract ; Albuminuria, Skin disease, boils, carbuncle, psoriasis, diarrhoea. ADDISON'S DISEASE. Characterized by pigmentation of the skin ; attacks of syncope and extreme debility ; Anaemia, often without emaciation. Vomiting, nausea, or epigastric pain. Discoloration is a bronzing colour, specially marked in face, hands, neck, groins, axillae, penis, scrotum ; areolae very dark ; buccal mucous membrane stained ; conjunctiva always free. Tendency to advance to death by asthenia. Sometimes termination is sudden. 30 CLIXICAL MEDICINE AND CASE-TAKING. PURPURA. Skin. — Description : Hseniorrliages into skin may occur in semTy, typhus, measles, variola, or from injury. Ecchymoses occur on forehead and under conjunctiva from asphyxia as * in epilepsy, if stage of tonic spasm is prolonged, and after severe paroxysms of hooping-cough. It comes out in successive crops in aggi'egations of spots. Note their size, situation ; whether separate or confluent. They do not fade on pressure, do not enlarge ; but others may occui' near those first produced, and become confluent with them ; they soon absorb, undergoing changes like a bruise. Some fade, while others appear. They occur mostly in dependent parts, and are apt to occur in the legs in cardiac or other obstruction. The spots may be small, "petechia," or elongated patches, "vibices," or in irregular patches, "ecchymoses." The colour is violet, purple, or blackish. At first the margins are abnipt, but these soon fade. Rarely the cuticle is raised, forming "blebs." Development of spots favoured by standing. Causation. — Hepatic disease ; rheumatism ; syphilis ; heart disease ; any debilitating conditions ; too restricted a diet. Not uncommon in old age, and accompanying insanity. Look for htemon'hages of gastro-intestinal canal. Albuminuria and signs of heart disease : albumen may be temporary. See Heart and state of Vessels. General condition of lassitude, with pain in limbs and joints. GENERAL DISEASES — CLASS II. 31 DEVELOPMENTAL DEFECTS. Head,. — Ill-shapen ; narrow, prow-shaped forehead ; hyper-ossi- fication in various parts. It may be too large or too small. lU-shapen in the anterior or posterior segments. Forehead overhanging. Face. — Hare-lip ; epicanthic folds in excess. Mouth. — Cleft palate and uvula. Eyes. — Coloboma of iris or choroid, i.e., a deficiency or cleft ; mall-shaped eyeball. Ea.rs. — Asymmetry ; one or both may be more or less rudi- mentary ; helix partly unrolled, with rudiment of third lobe ; frequently are deformed with ichthyosis. Skin. — Ichthyosis ; hair in excess on forehead, arms, back in children; eyelashes too long ; fine or coarse. Fingers. — "Webbed; supernumerary fingers or two thumbs, etc. ; inspect feet and toes. Heart. — See Congenital Defects. Special abnormalities. — Patency of abdominal rings , non- descent of testicle ; long prepuce ; imperforate anus ; nsevus. 32 CLINICAL MEDICINE AND CASE-TAKING. SENILE DEGENERATION. General condition. — Nutrition ; atrophy, or fatty growth. Goitre occasionally. W. = . Skin, hair, colour ; abun- dance. Involution of generative sj^stem. Locomotor system. — Power to move about; state of joints; power to walk. Nervous system. — Look for tremors and Paralysis Agitans. Sleep ; pains ; mental power ; memory ; neuralgia. Eyes. — Arcus senilis ; cataract ; presbyopia ; hearing and special senses. Vascular system. — State of Vessels; heart-force. Look for varicose veins ; purpura. Respiratory system. — Emphysema ; dyspnoea on exertion (cardiac). Digestive system. — Teeth, gums, jaw ; feeble digestion ; flatu- lence, constipation. Urinary. — Albumen. GENERAL DISEASES — CLASS II. 33 SENILE DEGENERATION. Sjjecial degenerative and 2Mthological tendencies. — The degene- ration may be simply atrophy, the skin becoming wrinkled, or there may be fatty growth generally under skin. Skin loses elasticity, becomes wrinkled and pigmented ; it loses transparency and brilliancy. Hair grows on chin in old women ; cancer. Nervous system. — Brain may be perfectly sound with an atrophied body. Prognosis as to life. — Soundness of the organs. The degree of senility not being greater than the age of patient indicates. Longevity is often inherited. Adaptation of patient's life to state of his body. 34 CLINICAL MEDICINE AND CASE-TAKING. ARTHRITIC DISEASES. ARTHRITIS. Note pain, tenderness, swelling, lieat, redness, effusion in joints, periarthritis. Deposits or enlargement of ends of bones or out-growth therefrom. Position of joints ; mobility or anchylosis. P. = ; T. = ; R. = . Look for signs of Rheumatism and its complications ^Gonor- rhcEal Rheumatism ; Gout and its history ; Rheumatoid Arthritis, especially when the arthritis has a chronic course with much stiffness and but little fever. Tabulate the joints affected, indicating the condition of each — "effusion," "swollen and painful," "tender and red," etc. RHEUMATOID ARTHRITIS. Joints. — Arthritis may be acute or subacute. There may be effusion, or only stiffness and pulpy feeling on manipula- tion. The hand, when made into fist and squeezed, is tender if finger joints are affected. Enumerate joints affected ; it may attack temporo-maxillary articulation, or stiffen cervical spine. Every joint in the body may be anchylosed. Dislocation of affected joints may occur. Causation. — Debilitating causes, haemorrhages, mental depres- sion, starvation , dampness, and possibly heredity. It may occui" at any age. ARTHRITIC DISEASES. 35 ARTHRITIS. JOINTS. EIGHT. I Shoulder. — Shoulder. — Elhow. — Elbow.— Wrist.— Wrist.— LEFT. Hand. — Note separately the Hand. — metaearpo-phalangeal joints and internodes. Hip. — Hi}). — Ankle. — Ankle.-^ Foot. — Specially note meta- Foot. — carpo-phalangeal joint of great toe. Temporo- maxillary and vertebral joints. RHEUMATOID ARTHRITIS. Small joints commonly first affected, but large joints may be equally attacked. The attacks last longer, are less severe ; less pyrexia and constitutional disturbance than with Gout and acute Rheumatism; more thickening left, with deformity of joints. No deposits of urate of soda ; no sweating. More commonly commences in fingers than toes, and not with a sudden short attack of single joints. Complications and accompaniments. — Any organic disease. Anaemia ; Neuralgia. 36 CLINICAL MEDICINE AND CASE-TAKING. RHEUMATISM. Histoiy of rheumatism ; heart disease ; chorea in family and in collateral relations. Previous attacks in patient. Present condition. — General signs of Fever. P. = ; T. = ; R. = . Skin moist, sweating, sudamina. Note any erythema. Joints. — Whether tender or painful on movement ; swollen with effusion, with or without cutaneous redness. Enumerate the joints affected, specially noting whether large or small joints are mostly affected. Vascular system. — Development of cardiac bruits from valvular disease ; pericarditis, with or without effusion. Always map out area of cardiac dulness. Pulse, regularity, etc. Eesjnra.tor]/ system. — Pleurisy, single or double ; extensive effusion common. Pneumonia, usually at base ; it may occur without special acute symptoms. Nervous system. — Rheumatism may alternate with chorea, one follo\^ing the other, near or at distant intervals. Occasion- ally delirium. Sleep. Urine. — Usually a deposit of pink lithates during fever. Rarely a trace of albumen. IthcumaMsm in children. — Symptoms often less severe than in adults ; less pain, but little fever ; skin often dry ; great tendency to heart disease, even when able to walk about ; often thought to be "growing pains ;" duration of fever a very few days, or it may be absent. Noddies wwdiQY skin not uncommon, even without arthritis or pain ; most common on prominences of bones or tendons, about elbow, knee, ankle, spine. They are usually accompanied by progressive heart disease. Minor sym,2ytoms.' — Liability to swollen joints on over-exertion ; stiff neck ; effusion in sheaths of tendons. Purpura. — Great liability of serous inflammations without arthritis. Erythema. ARTHRITIC DISEASES. , 37 RHEUMATISM. A febrile disease, characterized by pyrexia and arthritis with effusion, the inflammation changing from joint to joint and attended with great pain. Skin moist, often sweating ; this may be excessive and produce miliaria. Great tendency to serous inflammations attended with great effusion, usually quickly absorbed and not leading to suppuration. Tendency of all these conditions to relapse after convales- cence. Subacute attacks often succeed the acute. In children pain and fever often slight, but still tendency to heart damage very great. Nodules. — Small masses of fibrous growth from size of a pin's head to an almond, often felt better than seen ; painless, usually movable. Complications. — Inflammatory conditions ; endocarditis ; Peri- carditis; Pleurisy; Pneumonia; Bronchitis. Relapses of fever and arthritis. Erythema. Hyperpyrexia ; Delirium ; Chorea. Albuminuria occasionally. Tonsillitis is frequent at the onset with fever, or it may precede it by a week or two. At same time there may be stiff" neck. Causation. — Exposure to cold and wet. Inherited tendency. Tendency to recurrence, especially in early years. Exciting causes. — Exposure, over fatigue. Xote recent ante- cedents ; scarlet fever, tonsillitis, pharyngitis. 38 CLINICAL MEDICINE AND CASE-TAKING. GONORRHCEAL RHEUMATISM:. Joints. — Wrist and knee affected by preference. Pain and effusion ; much stiffness, often causing a considerable amount of anchylosis, No tendencj^ to suppm-ation, but infilti'ation and thickening around joint. Generative system. — Muco-purulent or gleety discharge from urethra. GOUT. Joints. — Enumerate joints affected. Note periarthritic inflam- mation and infiltration, deposit of concretion, or thickening of bones. Examine bursse for tophi. Take the history of previous joint affections. See Arthritis. Vascular system. — When gout has lasted many years the vascular system often degenerates ; Heart becomes dilated and hypertrophied, especially with Granular Kidneys. Pulse, force and tension. Digestive system. — General signs. These functions are often disturbed. Teeth much gi'ound. Liver disease common. Enquire for piles. Urine. — Often albuminous with signs of chronic Bright's disease. Amount of TJric Acid deficient. AETHRITIC DISEASES. 39 GONORRHEAL RHEUMATISM. Seldom seen in females. The disease runs its course through weeks or months. After slightly affecting many joints it becomes confined to one or two. No great pyrexia ; but little tendency to inflammation of internal organs. GOUT. An acute attack usually commences in early morning in one great toe. Severe pain, followed by swelling around the joint ; local oedema ; skin red and glazed, exquisitely tender. Attacks tend to recur at shorter intervals. Tophi or concretions of urate of soda may form around joints, in bursse, or in the external ears. Causation. — Most common in males at middle life. Hereditary tendency marked. Habits of intemperance ; exposure to weather. Plumbism. Any depressing circumstances or injury may excite an attack. Complications aind accompaniments. — Chronic Bright's Disease. Heart changes and Disease of Vessels. Skin affections ; psoriasis, eczema. Diabetes. Liver disease. Thrombus in veins. Tophi may discharge, forming sinuses. 40 CLINICAL MEDICINE AND CASE-TAKING. DISEASES OF THE NEEYOUS SYSTE:M NERVOUS SYSTEM. General conditions. — Intelligence ; Speech ; Sleep ; Head- pain ; Vertigo ; Coma ; Vomiting ; Paralysis ; Convul- sion ; Spasm ; Tremor ; Rhythmical Muscular Move- ments ; Delirium. INTELLIGENCE. — Giving good clear answers to questions. Memory : Memory for past events, or those of recent occuiTence ; power to perform easy calculations. The face may temporarily or permanently lose the expression of intelligence. SPEECH. — Stammering. Slow, jerky. Using inarticulate sounds only. Mute. Aphasia. SLEEP. — Easily falling asleep ; sleeping soundly and waking up refreshed in the morning. Wakeful ; disturbed by dreams ; remembering dreams. Insomnia, i.e. , loss of sleep. Raving at night. Somnambulism. Tooth gi'inding. HEAD-PAIN. — 1 . Its situation, whether general or local. 2. Its characters — heavy, dull, aching, throbbing, shoot- ing, darting, sense of fulness. Whether constant, inter- mittent, recurrent, or periodical. Its intensity and variability. 3. Effects of movement and change of position, of light and sounds, etc. 4. Its mode of onset. If previous attacks, note periodicity. 5. If accompanied by soreness or tenderness at particular spots, see Neuralgia. 6. Look to state of Special Senses, especially Sight ; Inquire for dysesthesia of sight. 7. If accompanied by Vomiting, note its relation to pain. 8. Look for signs of Brain Disease, Convulsions, Paralysis, Hysteria, Condition of Sensation. Examine Optic Discs. Look for Neuralgia. 9. Examine urine for sugar and albumen. 10. Character of pulse ; temperature. History of neurosis in individual or family. History of phthisis or strumous affections. DISEASES OF THE XERVOUS SYSTEM. 41 NERVOUS SYSTEM. Oeneral conditions. — Note all departures from the physiological condition. The muscular power should be such as to enable ordinary work to be performed. INTELLIGENCE may be naturally dull or mental power may be lost from disease, e.g., senile decay, dementia, general paralysis, epilepsy. Mental delusions may arise in sane people. Intelligence is proportioned to age, education, and surroundings. Ask as to school- work in children. SPEECH. — Aphasia = loss of faculty to speak words, though he can recognize them when written or spoken. Amnesia — loss of faculty for the memory of words, but can repeat them if suggested to him. SLEEP. — Restless tendency to turn the body may prevent sleep even if drowsiness is present ; frequent in Alcoholism, Insomnia may be caused by heart disease or over mental exertion. Muscular tmtching and cramps not uncommon from fatigue. Pain may prevent sleep. HEAD-PAIN. — The first thing to decide is whether the case be one of organic or functional disease ; in the latter case, the attacks, when recur^-ent, are commonly spoken of as headaches. HEADACHE may be pericranial, frontal, occipital, or diffused, or bilateral. Headaches may recur periodically ; in women frequently at the menstrual period. After an attack there is a certain amount of immunity. Attacks may be excited by over-work, sleeplessness, want of food, errors of diet, constipation, etc. With the attacks disorders of sight are common : sparks, coloured stars, zig-zags Avith coloured bright margins; hemiopia (seeing only half of any object looked at). Other senses may be disordered. Vomiting frequently terminates the attack. Accompanying the attacks, or alternating with them, may be much mental depression, mental weakness, and perverted ideas of things. Such recurrent headaches are common during pregnancy. Such attacks, accompanied by vomiting and coloured vision, are often spoken of as " bilious attacks." History. — Look for signs of Meningitis and Brain Disease. 42 CLINICAL MEDICINE AND CASE-TAKING, VERTIGO. I. Feeling of giddiness experienced by the patient, objects appearing stationary. II. External objects appear to move, e.g. , up and down, horizontally, approaching and receding. Vertigo may be increased or relieved by movement and position. Test hearing and sight. Examine for diplopia. Look for signs of Brain Disease. Anaemia. Examine Vascular System. Urine. COMA. History ; onset ; previous signs of Brain Disease ; Convulsions ; Vomiting. Causation. — 1. Injury to head. 2. Examine urine generally, and for sugar and albumen ; also for alcohol and poisons. 3. Cerebral Heemorrhage. See signs of Bright' s Disease. Vascular Degeneration. 4. Coma sequent to Convulsion. 5. Coma may occur during fevers. 6. Meningitis and coarse brain disease. 7. Heart failure. Examine pulse and heart's sounds. 8. Delirium frequently ends in coma. 9. Alcoholism and poisons. Circulation. — Xote pulse, small and soft in syncope, often hard in ursemia. First sound in heart failure. LooJc for signs of Brain Disease. State of Intelligence and Sensation. Test poAver to perform certain acts, e.g., protrude tongue, swallow food, move fingers, etc. Condition of sphincters. Note condition of sleep. Delirium. Subsultus tendinum. Position of body, e.g., dorsal decubitus. Character of respiration, whether stertorous. Examine for signs of Brain Disease and Paralysis. Examine urine ; lungs ; heart, its strength and sounds ; pulse ; condition of arteries. Smell breath for alcohol. (Edema. Temperature. Action of sphincters. Eyes : strabismus ; Pupils. Ophthalmoscope. Reflexes. DISEASES^ OF THE NEEYOUS SYSTEM. 43 VERTIGO. May occur during sleep or on waking. It is common at climacteric period with degeneration of vessels, Emphysema, Bright' s Disease. Vertigo may be due to diplopia dependent upon weakness of an ocular muscle or to some error of refraction as hypermetropia. Meniere's disease of ear ; Alcoholism ; excessive smoking ; mental or physical exhaustion ; dyspepsia ; anaemia; heart disease ; exposure to the sun. It may accompany simple recurrent Headaches . COMA. History. Coma may result from old-standing brain disease. There may be history of chronic disease capable of producing coma. Causation. — 1. Injury may produce compression of the brain. Collapse ; shock ; syncope. 2. See Uraemia. In Diabetes glycosuria may disappear before coma sets in. a. Extensive cerebral hsemorrhage may cause deep coma. Haemorrhage into pons causes universal powerlessness and contracted pupils, resembling opium poisoning. 4. Any severe exhaustion may cause coma. 5. Exposure to great heat, as summer sun. 6. Almost any brain disease may end in coma. 7. Arterial Disease may lead to cerebral haemorrhage ; heart disease to Embolism. 8. This is a great danger in fevers. Look for — Coma may be partial or complete, constant or remittent. Signs of motor power may be partially or wholly lost. It may be a sign of the Typhoid state, with delirium ; then the pulse is usually very soft. "Wandering at night in febrile diseases may pass on into Delirium and coma. The lungs are usually congested, with pulmonary oedema or hypostatic pneumonia. ExamiTie for Alcoholism; smell breath and test urine. The vomits or washings of the stomach may be smelt and tested for poisons — opium, alcohol, hydrocyanic acid. Urine may be obtained by the catheter. Stomach-pump may be used in poisoning cases. Avoid mistaking brain disease for poisoning. 44 CLINICAL MEDICINE AND CASE-TAKING. VOMITING. Describe vomits ; containing undigested food, frothy like yeast ; look for sarcinse ; watery ; smell ; containing blood or bile. See State of Tongue and bowels ; Abdominal Pain ; signs of dyspepsia. Look for reflex causes, e.^., pregnancy, Ovarian Tumour, disease of liver, Gall-stones ; Renal Calculus. Examine urine. Causatiaa. — Stomach disease or derangement. ffisophageal obstruction. Obstruction of Bowels. Poisons. Alcoholism. Uraemia. Hepatic disease. Pelvic disease. Pregnancy. Ovarian disease. Addison's Disease. Brain Disease or disturbance. Migraine. DELIRIUM. Its characters ; if attended with illusions and purposeless muscular movements, e.g., subsultus tendinum, picking of bed-clothes, etc. Test consciousness by speaking to patient and requiring an ansAver to a question, or that he shall protrude his tongue, etc. Causation. — Plumbism, Alcoholism, and such causes as may produce Coma. Belladonna. Camphor. TYPHOID STATE. Asthenia or adynamia. Temperature not high. Tongue tends to dryness, with crusting and formation of sordes on teeth and gums ; lips cracked and dry ; deglutition difficult. Pulse very soft, compressible, dicrotous, irregular. Heart's action weak ; first sound hardly heard. Tendency to pulmonar}^ congestion, cedema, and hypostatic pneumonia. Drowsiness ; Delirium ; Coma ; subsultus tendinum ; picking bed-clothes. Paralysis of sphincters or retention of urine. Dorsal decubitus complete. DISEASES OF THE NERYOUS SYSTEM. 45 VOMITING. If of cerebral origin it is — 1. Purposeless, not specially after taking food, and not relieving symptoms. 2. Tongue clean ; no special signs of Digestive Disturbance. 3. General absence of premonitory symptoms or nausea before vomiting ; contents of stomach ejected easily without retching or much effort. 4. Yomiting frequently aiTested by the horizontal position, recurring on becoming erect. 5. Concomitant signs of disturbance of the Nervous System or signs of Brain Disease. If vomiting appear to be of cerebral origin use Ophthalmoscope. Take temperature ; look for other signs of Brain Disease. Intermittent pulse is an early sigu of Meningitis in children. DELIRIUM. May be active ; violent ; low muttering. It usually commences at night with talking and wandering of the mind. AVhen moderate in degree temporary consciousness may be restored by speaking loudly and clearly, Is usual in the course of fevers. It may be due to simple exhaustion ; as from hsemorrhage after labour, etc. TYPHOID STATE. A prostrated condition, nervous symptoms, heart failure. An unfavourable termination of Delirium, Coma, delirium tremens, and acute febrile diseases. Note at each observa- tion strength of heart sounds, force of pulse, and the mani- festation of any further nervous symptoms. Dorsal decu- bitus is usually complete, i. e. , the patient lies flat in the trough of the bed ; muscular power is prostrated. If pro- longed, bed-sore may form. Albuminuria and hypostatic pneumonia frequently coincident. 46 CLINICAL MEDICINE AND CASE-TAKING. PARALYSIS. See Hemiplegia ; Palsy of Cranial Nerves ; Minor Paralyses. Test Motor Power. See signs of Brain Disease ; signs of Disease of Spinal Cord. View the part paralysed, and examine as to Motor Power. Note the parts paralysed and the muscles affected, stating whether the fine and general movements of the limb are wholly lost. Kote state of nutrition of the part, contrac- tions, rigidity, etc. Test reflex action by tickling, pricking, etc. See Sensation. Electric Tests. Examine Optic Discs. Look for signs of Syphilis. Vascular Degeneration. ELECTRIC TESTS. If one muscle contract to a lesser force of the cuiTent than another, it is said to be more irritable, To ascertain the irritability of a muscle reduce the strength of the current to the lowest point at which it will produce action. A full power of current simply shows the strength of the muscle. If in hemiplegia there be a well-marked difference in the reaction of the two sides the paralysis is not feigned. Diminished contractility may be due to disease of brain, cord, motor nerve, morbid condition of the muscle. The faradaic current may be applied over the muscle to be tested, or the galvanic current to the nerve supplying it. Loss of electric contractility is a sui'e sign of disease. Faradization is sometimes useful to prove the presence of muscle in a fat limb in which it is suspected that tissue is wasted. Functional aphonia may be from hysteria or exhaustion. Some- times the fauces, palate, and pharynx are anaesthetic. Laryngoscope shows healthy, motionless, white true cords, and a larynx otherwise healthy. Histoi'y — Often sets in suddenly. Liable to relapses. Look for Hysteria, Phthisis. Signs of mediastinal pressure. DISEASES OF THE NERVOUS SYSTEM. 47 PARALYSIS. Paralysis may depend upon disease of nerves or nerve-centres, or may be only Functional Paralysis. "When a muscle is paralysed, it usually atroj)hies in a short time, and on regaining strength regains its nutrition. In pseudo- hypertrophic Paralysis, the flexor muscles of the lower extremities become weak, but greatly enlarged. In paraplegia, see Spinal Cord Disease. Paralysed muscles often become rigid, e.g., hemiplegia, Infantile Paralysis. General muscular weakness, not dependent on simple debility and not secondary to disease of viscera, is seen in General Paralysis and Diphtheritic Paralysis. See Minor Paralyses. FUNCTIONAL. ORGANIC. Age and sex. — Most frequent at Most common in degene- onset of puberty and climac- ration ; sexes more equally teric period ; almost confined to females. Hysteria. — Present more or less. No signs of organic disease. ^ trophy of palsied iKtrt. — Palsied part well nourished. No bed-sore. Sensation. — May be lost, hy- persesthetic, or perverted. Reflex action. — Not obliterated. Electric tests. — Reaction readi- ly obtained. Palsy of Cranial Nerves. — Not seen. Aphonia. — Common ; may be the only palsy. Part paralysed. — Frequent change. Often partial of one limb or part. Sphincters not paralysed. Urine often re- tained. affected. No signs of Hysteria of Epilepsy. Disease of heart, kidneys, etc. Atrophy follows paralysis. Sacral bed-sore frequent. If lost temporarily, usually returns before motor power. In very many cases lost. Lost in disease of cord. Common ; specially of face and tongue. Rare from organic nerve disease. See Aphasia in right hemiplegia. 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M 03 O r-; o -^ g O M c Ol -O 2S S M «o 72 02 P^ Ph Gj ?-» ^ S <3i rt o 6 o ti- es OC 50 CLINICAL MEDICINE AND CASE-TAKINa. CONVULSION. Par oxy 3771. — Note the order, progress, and kind of spasm ; whether mostly Tonic or Clonic Spasm, Commencement, whether general or local ; commencing on one side, e.g., one hand or finger. Note suddenness of onset, whether attended with asphyxia and marked cyanosis ; its duration. Face pale or flushed ; fulness of veins ; whether distortion of face ; head retracted. Eyes : their position ; strabismus ; state of Pupils. Condition of consciousness. Premonitory symptoms. — Aura Epileptica; muscular twitches; dilatation of pupils. Causation. — Brain Disease ; Rickets ; Syphilis ; Bright's Disease ; Epilepsy; Hysteria. Acute diseases — (1) Cerebral ; (2) Febrile ; (3) Exanthemata ; (4) Pulmonary. Reflex exciting causes, e.g., indigestion, w^orms, teething, ear disease. Examine heart, urine, temperature. Sequelce. — Paralysis ; amaurosis ; strabismus ; defect of speech ; mental disturbance ; mania ; drowsiness ; sleep ; Coma. SPASM. 1. Tonic Spasm = continuous muscular contraction during a longer or shorter interval. 2. Clonic Spasm = alternate contraction and relaxation of muscles. racial Spasm is usually one-sided only. The successive clonic spasms are of equal extent and severity, so that successive grimaces resemble one another. In many cases it is chronic in duration and unaccompanied by other spasms. In these particulars it differs from Chorea. Writers' Cramp. — On attempting to wTite, the muscles ordinarily used in the act are thrown into a state of tonic spasm ; this subsides on discontinuing the act of WTiting. Other dissimilar acts may be performed without spasm. DISEASES OF THE NERVOUS SYSTEM. 51 CONVULSION. Paroxysm. — Usually commences wdth tonic spasm and pallor or cyanosis, followed by clonic spasms. One side or one limb may be primarily or chiefly affected ; then, occasionally, the eyes and head turn to that side, and there may be a few one-sided jerks of the head. Pupils usually dilated. Premonitory sym,ptoms. — In children, frequently, fist is clenched, with thumb turned in. Laryngismus may precede convulsion. Causation. — In children convulsions are very easily produced by slight causes. Ill-feeding, teething, worms, and Rickets very common predisposing causes. Pyrexia may be due to an acute disease or to continued tonic spasm. Urine may be albuminous from Blight's Disease, or may contain albumen or sugar consequent upon the convulsion. Sequelce. — Convulsions may be symptomatic of brain disease, which may subsequently advance. SPASM. Tonic Spasm is frequently attended by pain, and may be preceded by hypersesthesia. It is seen in the first stage of an Epileptic convulsion ; trismus, or lock-jaw ; tetanus ; spasmodic talipes ; spasmodic torticollis. Clonic Spasm may be increased by effort or mental excite- ment, and may subside during sleep and under chloroform, e.g., epilepsy. It causes movement or displacement of the limb or part affected. It is seen in chorea and muscular tic. Causation. — Look for signs of Hysteria. Reflex exciting causes, e.g., pregnancy, intestinal worms, teething. Dyscrasise, Ursemia, fevers, spinal irritation, and menin- gitis. Hydrophobia. Hysteria. Brain Disease. 52 CLINICAL MEDICINE AND CASE-TAKING. LARYNGISMUS. Look to Nervous System. Convulsion. General convulsions often follow. It may occur in hysterical women, but is most common in infants. Paroxysms may be brought on by excitement or fatigue. Look for Rickets, teething, constipation. There may be tonic contretction of muscles of limbs. TREMOR. L Tremor absent when at rest, but of various intensity when executing a more or less co-ordinated movement, e.g., raising a glass of water, picking up a pin. IL Tremor continuous and permanent. Purposive movements exaggerate it, but it does not disappear on repose. K'ote the sets of muscles affected ; whether head is moved ; whether muscles supplied by Cranial Motor Nerves are affected. Test Patellar Tendon Reflex, Take sample of patient's writing. RHYTHMICAL MUSCULAR MOVEMENTS. Athetosis = gliding movements, frequently repeated in the same order. Generally accompanies epilepsy, and usually: hemiplegic in situation. DISEASES OF THE NERVOUS SYSTEM. 53 LARYNGISMUS. Characterized by paroxysmal convulsion of the laryngeal muscles and noisy inspiration ; no specific catarrh or special lung trouble, as in Hooping-cough. Muscles of chest and abdomen may be involved. Most common in young boys, and on waking from sleep. It may become almost continuous crowing, the veins being distended and face distressed. Child rarely dies in an attack. TREMOR. In Paralysis Agitans, tremor continues when at rest. In Sclerosis, ti'emor is increased by movement, ceasing during repose ; so also in mercurial tremor. In paralysis agitans, the face, head, and cranial nerves usually escape. Sleep arrests ti'emor temporarily. Tremor may be general, affecting the head, or not ; it may be localized to a limb. Tremor is a simple vibratory repetition of purposeless movements, not displacing a limb greatly. Fine movements are those through small arcs. Muscular tremor is a characteristic symptom in paralysis agitans. Disseminated sclerosis ; Alcoholism ; mercurial tremor ; General Paralysis of the Insane. RHYTHMICAL MUSCULAR MOVEMENTS. Athetosis may be a congenital or an acquired disease ; it may be hemiplegic or both-sided. 54 CLINICAL MEDICINE AND CASE-TAKING. MOTOR POWER. Ability to stand, -walk, walk up stairs, work, etc. State some act the patient can or cannot perform ; how far he can Avalk. Power over large joints, small joints, finer movements of fingers, e.g., writing. Movements of upper mid lower extremities. — Test power of simple movement, and power to overcome resistance. Test movements of larger joints and muscles ; and power over individual digits. Movements of head and trunk. — Patient lying on his back, let him erect trunk -without use of hands. Examine spine. Respiratory movements. — Note respiratory rhythm ; movements, whether principally thoracic or diaphragmatic. Co-ordinaMon of the limbs. — Gait in walking ; walking well and firmly with head erect ; also walking straight with eyes shut ; walking stiff, one joint being kept immobile from pain ; hip movements much restrained in Sciatica. Circumducting one leg, s\vinging it round, not moving it forward as the other, seen in Hemiplegia. Staggering, moving trunk over place where the legs are. Lifting legs inordinately high, then bringing them suddenly down. Walk with eyes shut. Test for Muscular Anaesthesia. DISEASES OF THE NERVOUS SYSTEM. 55 MOTOR POWER May be lessened from general weakness or be lost in one or two extremities only, or in a certain group of muscles. See Paralysis. Movements of upper and lower extremities. — Palsy of upper extremity, if of cerebral origin, is usually accompanied by weakening of lower extremity. Let patient move limbs to order ; lift weights ; pick up a pin, etc. Movements of head and trunk. — Motor power over spine may be lost from caries of spine. Pseudo-hypertrophic Paralysis. View spine ; feel for curvatures. Respiratory tnoxiements. — Cheyne's respiration. = a series of respirations hurried and deep up to a certain point, then subsiding to a dead pause. Go-ordination of the limbs. — If defective, examine joints. Sciatica. Spasms. Tremors. Paraplegia. Chorea. In Paralysis Agitans there is a tendency to propulsion or retropulsion. In General Paralysis, stumbling and staggering, or tottering. In Ataxy, muscular power in the legs is not lost ; the patient may walk, feeling the ground with a stick. In Hemiplegia the patient in walking swings round the leg, and then keeping it stiff balances the trunk upon it. 56 CLINICAL MEDICINE AND CASE-TAKING. SENSATION. Objective sensibility (ascertained by examination). — Tactile sensibility of skin. Examine separately the flexor and extensor surfaces, face, trunk. Test tbe least distance at Avbich two points can be distinguished in various regions. Sensibility to heat and cold. Apply to various parts two test tubes, one containing hot water, the other cold. Or apply a hot and cold sponge alternately. Subjective sensibility (sensations experienced by patient). — Localized pain in the area of a certain cutaneous nerve, constant or periodical, suggests enquiry as to Neuralgia. Sensibility may be lessened, anaesthesia ; exalted, hyper- esthesia. Sensation may be perverted, the patient ex- periencing altogether abnormal sensations, dyssesthesia, e.g., numbness, "pins and needles," a sense of burning, heat and cold. If subjective sensations are complained of, examine for an objective cause, e.g., local tenderness, local inflammation or disease, periostitis. Reflex causes, gasti'ic, uterine, etc. See Head-pain, Vertigo, Hysteria, Neuralgia, Muscular Anaesthesia. MUSCULAR ANESTHESIA. Let patient carry his hand to his mouth, and repeat the act with his eyes shut ; let him state the position of his limbs A^-ith his eyes shut ; let him distinguish between diff'erent weights. In all such attempts he fails. Test reflex action, and electric excitability (usually diminished). Note what muscles are aff'ected ; state of muscular nutrition ; presence or absence of pain. Test cutaneous sensibility. DISEASES OF THE NERVOUS SYSTEM. 0/ SENSATION. Anaesthesia, loss or diminution of sensibility ; hypersesthesia, exaltation of sensibility. Both these conditions frequently met with in Hysteria. Hemianaesthesia is usually functional ; it may paralyse the special senses of side affected ; it is frequent in hysteria. Analgesia is the loss of sensibility to pricking, pinching, etc. It may be temporarily removed or transferred to the other side of the body. Subjective sensibility may be ansesthetic, hypersesthetic, or dyssesthetic, i.e., sensibility may be lessened, exalted, or perverted. The brain centres of the organs of special sense may be altered in any of these ways ; so also the sense of touch. As sensations of physical life we may speak of "organic sensations," or those due to the changes occurring in the organs of digestion, circulation, respiration, etc. ; the "appetites," a group of uneasy feelings produced by the recurring wants or necessities of the physical system, as sleep, exercise, repose, thirst, hunger, etc. Special dysaesthesise are the epileptic aura, the lightning pains of ataxy, the sensation of girthing frequent in spinal cord disease. MUSCULAR ANESTHESIA.* ' ' A loss of the feeling of muscular action, attended by irregularity, sluggishness, and diminished force of volun- tary movement ; but unattended by any necessary loss of cutaneous sensibility or by distinct paralysis." A condition frequently seen in Hysteria. Usually there is no pain in the limbs, but pain is common in Locomotor Ataxy. It may be local. It often precedes paraplegia. Usually impaired or lost in General Paralysis. Some muscular anaesthesia may accompany attacks of migraine. See Headache. * Dr. Reynolds' " System of Medicine." 58 CLINICAL MEDICINE AND CASE-TAKING. SPECIAL SENSES. Sight. — Test acuteness of vision witli test-type. Examine for perception of colour. To completely examine the sense of sight, further test poAver of accommodation, refraction, action of ocular muscles separately and in the combined movements of the eyes. Examine the field of vision. See Pupils. Ophthalmoscopic Appearances. Hearing. — Test hearing with a watch held at the greatest distance at which it can be heard from each ear. If watch cannot be heard thus, test auditory power of the nerve for sounds conducted through the skull, i.e., place watch on forehead or between teeth. Look for otorrhoea ; examine throat ; use ear speculum. Taste. — For acids, bitters, sapid substances ; determine each separately at anterior and posterior portions on either side. Smell. — For pungent substances, e.g., ammonia; aromatic substances, e.g., oil of cinnamon. CRANIAL NERVES. Observe movements of eyes, tongue, face, lips, palate, muscles of mastication and deglutition. Pupils. Test Special Senses ; sensibilit}'" of head and face. Nerve I.— Olfactory, See Smell. Nerve II. — Optic, see Sight, Pupils, Ophthalmoscopic appear- ances. Nerve III. — (Palsy). — Ptosis or drooping of the upper eyelid ; permanent external strabismus ; dilated pupil ; loss of accommodation for near objects. Nystagmus = purposeless vibratory movements of the eyes ; usually the movements are in the horizontal plane. Nerve IV. — Superior oblique muscle. Palsy produces no appreciable deviation of the axis of the eye, but diplopia results and the diagnosis generally depends upon the relative position of the two images. Nerve V. — Motor to temporals, masseters, and pterygoid muscles. Examine condition of its separate branches. See Neuralgia, Trigeminal. Examine power of Taste. Look for tooth grinding. . DISEASES OF THE NERVOUS SYSTEM. 59 SPECIAL SENSES. Sight — Defects may occm- from errors of accommodation, myopia, hypermetropia, or astigmatism, from changes in the optic nerve or other parts. Illusions may represent an aura preceding an epileptic fit ; common in delirium and insanity, not uncommon with recurrent Headache. Hearing. — Deafness may result from obstruction of the Eusta- chian tube from pharyngeal catarrh, or tonsil disease ; wax in ear ; disease of tympanum. The nerve may be paralysed from disease, e.g., Syphilis; rarely from cerebral tumour. Tinnitus common with and without ear disease. Taste. — Taste may be lost on one side only. It is impaired in some cases of palsy of Nerve YII. Smell. — Test either nostril separately. CRANIAL NERVES Are some sensory, others nerves of special sense, while others are purely motor. The condition of the parts that they supply, as found on examination, often throws much light on the condition of the brain. Paralysis of an ocular muscle or the tongue would indicate intra-cranial disease. Nerve III. — Paralysis often partial, e.g., ptosis only. Accom- modative power alone may be lost, e.g., in Diphtheritic Paralysis. This nerve is frequently paralysed from Syphilis. Nystagmus. — A chronic condition, usually congenital, and dependent upon deeply-seated brain lesion. Nerve V. — Sensory branches give sensibility to the lateral and anterior parts of the head and the eyeball, and common sensibility with taste to the anterior two-thirds of the tongue. It is the afferent nerve in reflex winking on touching the eyeball ; if palsied, the eyeball becomes insensitive and the cornea ulcerates and sloughs. See Neuralgia, Trigeminal. €0 CLINICAL MEDICINE AND CASE-TAKING. CRANIAL NERVES. Nerve VI. — External rectus of the eye. Nerve VII. — Examine movements of face in natural expression, in forced voluntary movements, e.g., to giin and show teeth, to frown, to elevate the forehead, to whistle. See respiratory movements of alee nasi. Facial movements, are they symmetrical ; compare the two sides of the face. See position of the angles of the mouth, and slope and curve of the upper and lower lips. The depth of the naso- labial groove. Orbicularis oris, its power of holding air in the mouth with the cheeks blown out. Orhiciilo.ris oculi^ its action in closing the eyelids, in producing similar folds of the eyelids on the two sides ; a similar width of palpe- bral fissure on the two sides ; a firm application of the lower eyelid to the globe, with the punctum applied to the conjunctiva. Note action of Occipito-frontcdis and Cwru- gatoT. Test reflex actions of the eyes. Note pronunciation. Examine with care the movement of the soft palate and tongue. Test Hearing, Sight, Smell, Taste. Look for dryness of mouth from want of saliva. Nerve VIII. — Pneumogastric ; Glosso-pharyngeal ; Spinal Accessory^ Pneumogastric. Not pui-ely a cerebral nerve ; partly spinal, and receiving branches from the sympathetic. Motor braiiches. — To larynx, pharynx, oesophagus. Pharyngeal, concerned in reflex act of deglutition. Sujjerio^' laryngeal. — Mostly sensory, but motor to arytenoid and crico-thyroid. Its stimulation inhibits inspiration, e.g., when opening of larynx is irritated. DISEASES OF THE NERVOUS SYSTEM. 61 CRANIAL NERVES. Nerve VI. — It is opposed by Nerve III. Nerve VII. — Motor to muscles of face, these muscles being used in expression, respiration, eating ; certain reflex actions, e.g., eyelids, mouth. Intra-cranial branches. — Ch'eat petrosal through Michel's gang- lion to levator palati and azygos uvulae. Small 2)etrosal through otic ganglion to tensor palati and tensor tympani and parotid gland. Tympanic branches to stapedius and laxator tympani. Chorda tyr)i2Kini to submaxillary gland and lingualis. Bell's Paralysis of the Face differs from the facial paralysis produced by brain disease in being more complete and general in distribution ; in the latter the muscles about the angles of the mouth are mostly affected as seen in grinning. Bell's paralysis affects all the muscles on the side of the face ; the eyelids, however, retain a little power. The creases of the face are obliterated, as seen on the forehead and in the naso-labial groove ; the eye remains more or less permanently open, and the tears overflow. The patient cannot distend the mouth with air, and food accumulates in the cheeks. Causation. — Cold, disease of ear, syphilitic disease of temporal bone, pressure of glands on facial nerve. Nerve VIII.— Pneumogastric nerve. — Is concerned in certain reflex actions, e.g., deglutition, reflex movements of glottis. Pharyngeal branches. — Palsied in Diphtheritic Palsy, in Bulbar Paralysis, and much dulled in the Typhoid State. Con- cerned in reflex throat cough. Sicjjerior laryngeal. — Afferent nerve in reflex movements, closing larynx in deglutition or when irritated. 62 CLINICAL MEDICINE AND CASE-TAKING. CRANIAL NERVES 2{erve VIII. — Continued. Recurrent laryngeal. — Chiefly motor ; supplies all the muscles of the larynx except the crico-thyroid. Cardiac hranclies. — Inhibitory ; pulse may be irregular from brain disease, and small from mental depression. Pulmonary branches. — Afferent fibres convey the feeling of the necessity to breathe. Motor fibres supply the bronchi. Gastric branches. — Regulate the peristaltic movements, and the secretion of gastric juice. Abdomviud branches. — Supply liver and are connected with the renal plexus. Glosso-pharyngeal nerve. — Gives common and gustatory sensi- bility to the tongue, supplying circumvallate papillse at back of tongue. Spinal accessory nerve. — A motor nerve closely associated with the pneumogastric and giving it motor fibres, some of which go to larynx. Nerve IX. — Principally motor to the tongue and depressors of the larynx and lower jaw. DISEASES OF THE NERVOUS SYSTEM. 63 CRANIAL NERVES. Nerve VIII. — Continued. Recurrent laryngeal. — Left winds round arch of aorta, right round innominate artery. When paralysed glottis is passively narrowed on inspiration, and passively dilated on expiration. It may be paralysed by thoracic Aneurism or mediastinal tumour, and thus lead to palsy of cor- responding vocal cord. Tulmonary hranclies. — Concerned in spasmodic Asthma, Hooping-cough, Laryngismus Stridulus. When para- lysed leads to congestion of the lungs, e.g., in Typhoid State. Gastric branches. — Afferent in cerebral Vomiting. Dyspepsia may result from brain disturbance. Ahdominal branches. — Mental shock may excite Diabetes. Anxiety causes flow of pale urine of low sp, gr. Glosso-pharyngeal nerve. — It is concerned in reflex deglutition Spinal accessory 7ierve. — Motor to sterno-mastoid and trapezius ; fibres pass to the larynx and control the voice, not respira- tory movements. Nerve IX. — Concerned in articulation, mastication, and the commencing act of deglutition. Each function may be separately lost. 64 CLINICAL MEDICINE AND CASE-TAKING. BRAIN DISEASE, SIGNS OF. Head-pain ; Vertigo ; Cerebral Vomiting ; Convulsion ; Paralysis ; Hemiplegia ; palsy of Cranial Nerves ; sti-abis- mus ; palsy of Special Senses. Mental or intellectual disturbance : Coma ; Aphasia. Changes in Optic Nerve. Pnlse, interniittence of. Pupils. See general condition of the Nervous System ; Sensation ; Hysteria. ExoAnirmtion. — Look for history of neuroses ; previous signs of Brain Disease. Indications of acute diseases, e.g., take temperature and look for other signs of Fever. Examine vascular system and urine. OPHTHALMOSCOPIC APPEARANCES. Test sight and examine Pupils previous to using ati'opine. Some of the principal conditions of the fundus that may be observed are — Optic Neuritis ; Optic Atrophy, (1) primary, (2) secondary to neuritis or consecutive atrophy ; over-fulness of veins ; emptiness of arteries ; Haemor- rhages ; Choroiditis ; Tubercle of Choroid ; retinitis albumin urica. OPTIC NEURITIS. — Disc blui'red, outline indistinct ; vessels on disc in parts covered with effusion ; veins large. Yision may be perfect. ^Neuritis is very indicative of coarse intra-cranial disease, e.g., Tumour. This condition may subside, leaving but little change noticeable, or it may leave consecutive atrophy. See signs of Brain Disease. OPTIC ATROPHY.— May he sec|uent to neuritis. It differs in appearance from primary atrophy in having more disturbance of the choroidal pigment around the disc, a less sharply-defined margin, and sometimes thickening of the sheaths of the vessels remains ; it looks dull. Primary optic atrophy gives a more clearly-defined margin ; it is clean cut, and its general appearance brighter. Vessels atrophied or obliterated. DISEASES or THE NERVOUS SYSTEM. bD BRAIN DISEASE, SIGNS OF. The condition of the brain may be judged of by observation of the optic discs and retina, as expansions of nerve matter in connection with the circulation of the brain. Also by the condition of parts supplied by nerves having their centres in the brain. Special signs are found in conditions of the muscles, paralysis, spasm, convulsion, want of co-ordination, etc. See Motor Power. Exami nation. — Onset of acute febrile disease may cause cerebral symptoms. Cerebral symptoms with pyrexia contra-indicate a purely functional disturbance. OPHTHALMOSCOPIC APPEARANCES. HiEMORRHAGES in the fundus are usually situated in the retinffi. They are common in Pernicious Anaemia ; in Retinitis Albuminurica — here they are accompanied by white shining spots. They may be seen in ague and leucocythasmia. Haemorrhages, even if considerable, may be quickly absorbed, and may recur. CHOROIDITIS.— Dull yello^vish patches over fundus ; there may be subsequent atrophy, the shining sclerotic showing through. Around the patches the choroidal pigment is much disturbed, forming black rings or patches. It may be disseminated or marginal. It is often syptilitie. TUBERCLE OF CHOROID.— Small circular spots, more or less circumscribed, reddish or greyish-white in colour. They may be elevated above the level of the choroid with retinal vessels passing over them ; adjacent choroid may be normal. Their growth in size may be watched. See General Tuberculosis. TUBERCLE IN CHOROID is rather a sign of general tuberculosis than a sign of meningitis ; but coincident optic neuritis indicates probable tubercular meningitis. Tubercle in choroid in a case of continued fever suggests tuberculosis as its cause. F 66 CLINICAL MEDICINE AND CASE-TAKING. PUPILS* Let a full light fall upon the face. Keep one eye covered and test the other ; letting light suddenly fall upon it, observe its reaction. Partially screening one eye, let light fall suddenly upon the other, and observe the reflex effect upon the first eye. This reaction involves the optic nerve on side exposed to light, corpora quadrigeniina, and Nerve III. on the side shaded. Note contraction of pupil on near accommodation. Observe. — 1. Its shape, regularity, and outline ; adhesions may cause irregularity ; shape when dilated. 2. Size ; may be measured by reference to the holes of catheter gauge. 3. Activity to light and on near accommodation. 4. Any differences between the two pupils. 5. Colour of iris, distinctness of muscular bundles. Mydriasis = great dilatation of pupil. 1. Artificial, by atropine. 2. Paralytic, from palsy of Nerve III. 3. Spasmodic. Myosis =■ contraction of pupil. * See Mr. Hutchinson's article on " States of the Pupil." " Brain," Vol. i. ii. DISEASES OF THE NERVOUS SYSTEM. 67 PUPILS. Large in Anaemia and debility ; dilated during rigor and Convulsion. May be exceedingly mobile in debility. Sluggish pupils indicate defect of vaso-inotor nerve, and then the pupil is rather small. A pupil sluggish to the direct action of light may respond immediately when the other eye is acted on by light, thus — (1) Irido-motor appa- ratus is sound ; (2) Peripheral structures of the second eye are sound ; (3) There is a defect in the percipient structures of the first eye. Pupils may remain active with optic atrophy. The movements upon accommodation (Xerve III.) may be good though reaction to light (vaso-motor) be lost, e.g., in Ataxy. Precise symmetry in size of the eyes is not common. Iridoplegia — palsy of pupil to light, but not to drugs. Cyclojylegia = absolute loss of accommodation. Ophthahyiojjlegia interna = both the radiating and circular fibres of iris and the ciliary muscle are paralysed. Pupil is motionless and accommodation lost. Iritis may be a sign of previous Syphilis. 68 CLINICAL MEDICINE AND CASE-TAKING. SPINAL CORD DISEASE, SIGNS OF. Paraplegia, partial or complete ; Spasms ; Tremors. Dysaesthesia, principally confined to the lower extremities ; Paralysis of Sphincters ; sacral bed-sore ; atrophy of optic nerve. Motor poiver. — See power of co-ordination of the limbs ; their state of nutrition. Enquire as to the state of sphincters. Test reflex action of extremities and patellar tendon reflex.* If there be paralysis, state what groups of muscles are involved, and which escaped ; gait in walking. Sensation. — Objective sensibility ; examine the muscular sense. See Muscular Anaesthesia. Subjective sensibility ; dyssesthesia of lower extremities. Look for Ophthalmoscopic appearances; condition of spine. See Pupils. Causatimi. — Exposure to cold ; over-exertion ; functional para- j)legia in hysteria ; heredity ; reflex paraplegia, from urethral stricture, sequent to confinement ; spinal menin- gitis ; spinal hsemorrhage ; injury to back ; Syphilis ; Alcoholism. * Dr. Gowers: "Med.-Chir. Trans." 1879. DISEASES OF THE NEEVOUS SYSTEM. 69 SPINAL CORD DISEASE, SIGNS OF, Muscles supplied by spinal nerves are alone paralysed. See if signs of Brain Disease and Palsy of Cranial Nerves are absent. Paraplegia may be purely functional. Motor power. — If there is paralysis of a special gi'oup of muscles, see Minor Paralyses. Specially note the power of Co-ordination of the Limbs. Sensation. — Sensation of girthing round abdomen, frequent in spinal cord disease. *' Lightning pains," darting, burning, or pricking; common prodromata of Ataxy, often mistaken for rheumatism. Look for sacral bed-sore, very apt to form in myelitis, probably as the direct effect of the nervous lesion. Ko bed-sore in Hysteria. Test reflexes. Causation. — Reflex paraplegia seldom complete, less widely- spread, and less defined than paraplegia from myelitis. See Paralysis, Functional or Organic. 70 CLINICAL MEDICINE AND CASE-TAKING. MINOR PARALYSES. Paralysis of isolated muscles, or groups of muscles. Spinal (Infantile) Paralysis. Onset sudden ; most common in infancy ; frequent in liealthy children ; occurs but once ; large muscles principally aflected, e.g., deltoid rather than. muscles of fingers. PROGRESSIVE MUSCULAR ATROPHY.— A chronic disease causing atrophy of certain muscles, with corresponding loss of power, attacking shoulder and ball of thumb by preference, gradually involving more muscles ; no pain. PSEUD 0-HYPERTROPHIC PARALYSIS.— Enlargement of muscles paralysed ; usually attacks calves, thighs, buttocks, erector spinal muscles ; mostly seen in children — male children ; several children in same family may be affected. PARALYSIS OF EXTENSORS OF FOREARM.— Usually due to plumbism. CROSS PARALYSIS.— Palsy of face on one side, and hemiplegia of the opposite side. LABIO-GLOSSO-LARYNGEAL PARALYSIS (Bulbar para- lysis). — Paralysis of muscles of tongue, palate, pharynx, orbicularis oris ; death by asphyxia. PARALYSIS OF THE FACE.— See Bell's Paralysis. Paralysis of muscles of deglutition frequently due to Diphtheria. NETTRALGIA. Symptoms. — Onset, whether sudden or gradual, whether pre-; ceded by general or local disturbance ; the paroxysms, whether severe, their frequency, the character of the pain. The effect of heat and cold upon the pain. Look for tender points in the course of the nerve affected, and its branches. Examine cutaneous sensibility at the seat of pain. Causation. — Age, sex, heredity, injury to neiTe, frequent move- ment of the limb, or pressure upon a nerve. Malaria, Syphilis, Gout, Rheumatism, Alcoholism, Anaemia, Hysteria, cold, mental anxiety, carious teeth. Reflex causes, e.gf., from pregnancy, pain in eyeball from caries of a tooth. Conditions cTiaroAAerised hy neuralgia. — Locomotor Ataxy, lower extremities ; Herpes Zoster, a long area of skin supplied b; nerve affected ; Herpes Labialis. DISEASES OF THE NERVOUS SYSTEM. 71 MINOR PARALYSES. Paralysis of isolated muscles, or groups of muscles. See Infantile Paralysis. PROGRESSIVE MUSCULAR ATROPHY.— Enquire for injury to nerves ; lead poisoning ; the nature of the employment, as to its using one particular set of muscles. Electric tests. Irritability of muscles when struck. Cutaneous sensibility, PSEUDO-HYPERTROPHIC PARALYSIS.— Test reflex action, and electric tests. See motor power. PARALYSIS OF EXTENSORS OF FOREARM.— Supinator longus and extensor carpi rad. longior usually escape. CROSS PARALYSIS.— May be due to disease of pons. LABIO-GLOSSO-LARYNGEAL PARALYSIS.— Often accom- panies hemiplegia and chronic brain disease. PARALYSIS OF FACE.— May be due to lesion of brain, or Bell's Paralysis. NEURALGIA. Symptoms. — Pain localized, almost invariably unilateral ; in recent cases paroxysmal or distinctly intermittent. Gradual formation of tender points, where nerve-branches become superficial, passing through bone or fascia, the points of Valleix. * Absence of local causes of pain, sucli as inflammation, periostitis, new growth. Absence of fever or local heat. Causation. — Most common in females at puberty ; when developing at forty years or older, is very intractable. Malarial neuralgia, usually in supra-orbital nerve. Injury to a nerve may cause neuralgia of branches communicating with it. Conditions characterized by neuralgia. — The subjects of hysteria and epilepsy are very liable to neuralgia. * See Anstie on " Neuralgia." 72 CLINICAL MEDICINE AND CASE-TAKING. NEURALGIA. TRIGEMINAL.— Tender points. 1. Supra-orbital. 2. Palpebral, iu upper eyelid. 3. Nasal, at junction of nasal bone and cartilage. 4. Ocular, a point in the eyeball. 5. Trochlear, at inner angle of orbit Superior maxillary division. — 1. Intra-orbital. 2. Malar. 3. A point in the line of the upper jaw. Iiiferior division. — 1 . Temporal, a little in front of the ear. 2. Inferior dental (mental), towards front of lower jaw. 3. Lincrual, at side of tongue. SCIATICA. — Is a neuralgia of the sensory fibres of the sciatic plexus. Note gait in walking ; the muscular power of the limb ; the state of its nutrition. Look for tender points — along the com'se of the nerve and its branches, e^g., superficial cutaneous branches in gluteal region ; down back of thigh, calcanean and malleolar branches ; also behind trochanter. INTERCOSTAL NEURALGIA.— There is pain and tenderness in the course and distribution of the nerve or nerves afiected. It is most common in the left infra-mammary nerve. Pain is constant, at times shooting. Painful points. 1. Vertebral. 2. Lateral, along outer margin of trapezius. 3. Sternal. DISEASES OF THE NERVOUS SYSTEM. NEURALGIA. TRIGEMINAL. — Causation : Any cause of neuralgia, especially malaria ; dental or maxillary disease ; cerebral tumour. It mostly occurs in conditions of low nervous depression. Some severe cases are associated with, hereditary insanity. With disease of trigeminal nerve there may be profound disturbance in the eyeball, as in cases of herpes in this region. Ulceration of Cornea, iritis, suppuration, and disorganization. SCIATICA. — CaiisaMon : Rare under twenty years. Cold ; peripheral irritation, e.g., tight boots. May arise from pressure on the sacral plexus, e.g., pelWc tumours, ovarian, hard fseces. Examine hip-joint. Pain is more constant and less paroxysmal than in other neuralgia ; motor as well as sensory fibres often affected, diminishing muscular strength ; the limb may emaciate and become somewhat ansesthetic. In walking, the foot on side affected is planted carefully, so as to avoid any jar which would increase the pain. 74 CLINICAL MEDICINE AND CASE-TAKING. HEMIPLEGIA. State side affected. Give history of the onset, whether sudden, gradual, with convulsion or loss of consciousness ; whether preceded by abnormal sensations ; whether first attack. p, (7, —General condition of Nervous System. Look for palsy of Cranial Nerves. Examine limbs affected as to Motor Power, coarse movements, e.g., power to raise limb from the bed, to move large joints, pronate and supinate ; to lift weights. As to finer movements, e.g., use of fingers, to pick up a pin, button shirt, point with index and little fingers, etc., to write. Note power of tongue and face. Palsied limbs, their temperature, atrophy, or rigidity, condition of Sensation. Look for signs of Brain Disease. Special Senses. Condition of cranial nerves. Sight, examine for limitation of the field of vision. Facial Palsy from cerebral disease. Examine Optic Discs. Look for bed-sore. Causation. — Examine heart, and look for signs of Vascular Degeneration. Look for signs of Bright's Disease. Look for signs of Syphilis. Hysteria. Superficial reflexes diminished on side of palsy. Rigidity in part paralysed later on. If involuntary movements of parts palsied. DISEASES OF THE NERVOUS SYSTEM. - 75 HEMIPLEGIA* Right hemiplegia commonly associated with Aphasia. Hemi- plegia from Embolism most commonly right-sided. Onset sudden in embolism, and in cases of extensive haemorrhage. Sometimes premonitory warnings are experienced in the head or limbs. P.C. — Nerve YIL, when affected, is usually partially paralysed, muscles about mouth being most weakened. There may be the following phenomena : — 1. Head turned to side of lesion. 2. Conjugate deviation of the eyes, both being turned to the side of lesion. 3. Muscles of chest and belly weakened on side opposite to lesion. 4. Paralysis of muscles passing from the trunk to the limbs paralysed. 5. The face paralysed on the side of hemiplegia. 6. The tongue protruded to side of hemiplegia. 7. Arm and leg paralysed on the side opposite to the lesion. Nos. 1 and 2 are very temporary. Those parts suffer most and longest which have the most voluntary uses. Sensi- bility is usually restored before motor power. Causation. — Valvular Disease of the Heart may lead to em- bolism, Atheroma to cerebral hsemorrhage or thrombus. Bright's disease, being associated often with disease of vessels and hypertrophy of heart, frequently leads to cerebral haemorrhage. Syphilitic disease of arteries. * Dr. Hughlings- Jackson : Reynolds' " System of Medicine." CLINICAL MEDICINE AND CASE-TAKING. CHOREA. If there have been previous attacks, say whether one-sided, and state side affected. The manner of commencement. Previous history as to the general condition of the Nervous System. History of school-life, Headaches. F. H. 0/ Neuroses, headaches, hysteria, chorea, fits in infancy epilepsy. Rheumatism. p. (7. — Xote state of nutrition ; general condition of the ner- vous system. Look for signs of Brain Disease. Specially note condition of Intelligence, Speech, Sleep. Motor Power. — Whether muscles supplied by cranial and spinal nerves are alike affected. Examine face, tongue, soft palate, movements of eyes, movements of head, respiratory movements, movements of trunk and head. Examine the extremities in detail, e.g., right upper extremity. Is the shoulder much moved ? in which direction principally '? by the action of what muscles ? The elbow, is it more or less moved than the shoulder ; what are the principal movements — flexor, extensor, pronator, or supinator ? The hand ; movements of wrist, fingers, thumb. Fingers may tAvitch with extensor-flexor or adductor-abductor move- ments ; some digits may move more than others. Postures of hands when held out, also of trunk and spine. Complicatioois.— Onset of Rheumatism, Pericarditis, Endocar- ditis. Mental symptoms. Look for Rheumatic Nodules. EoMmine heart, its sounds, regularity. Look for signs of Anaemia. Examine urine for urea and uro-hfematin. Causation. — The most distinctly demonstrated lines of causation are in connection with Rheumatism, Heart Disease, and sudden mental impressions. Reflex causes, e.g., intestinal worms, pregnancy. Enquire for arthritis with enlargement, attended with feverishness or not ; over-work, or complaint of school lessons. DISEASES OF THE NERVOUS SYSTEM. 77 CHOREA. S2)ecial character of the tnuscular movements. — Are the move- ments due to mere clonic jerks of certain muscles, repeated in a meaningless manner (muscular tic), or are they of the character of gesticulations, wriggling, testing movements, flinging the limbs about ? Do the movements greatly displace the limbs, or after the movements do the limbs always fall back into their previous position ? Are the movements independent of voluntary efforts ? are they increased by voluntary efforts ? are they equal on the two sides ? Accompanying muscular weakness. Urine often of high sp. gr. and loaded with urea. SCLEROSIS.* CHOEEA. Rhythmical oscillations. In The main direction of lifting the arm, the main motion is disturbed from the direction of the movement outset by contradicting move- persists in spite of the obsta- ments which cause the goal to cles caused by the jerks of the be missed. Movements sud- tremors, and it reaches its den, and unexpected when the goal. limbs are at rest, and apart from the action of the will. Complications. — In pregnant women miscarriage is frequent and attended with danger. Examine. — Mitral bruits, very common. Urine often scanty and very dense, being loaded with urea ; uro-hoematin often in large amount. Causation. — The connection with rheumatism is shown by its occurrence before, after, or with the chorea. The frequency of cardiac bruits has suggested that the disease is due to embolism. If pregnancy excites chorea, there has usually been chorea in childhood. Chorea most common in females, and in childhood near puberty. Exciting causes — fright, falls, etc. , over- work at school, imitation. Enquire for symptoms before occurrence of acute movements ; whether fidgety, frequently dropping things, clumsy, nervous. * Charcot ; New Syd. See. Trans. 78 CLINICAL MEDICINE AND CASE-TAKING. HYSTERIA. Describe briefly patient's complaints. State if able to perform ordinary work ; if not, say why. Enquire if any "attacks, fits, or Convulsions occur ; " if they do, note time and cir- cumstance. Note general condition of Nervous System; signs of Brain Disease. Motor Power. — General character of movements, whether active or sluggish. Test reflex excitability. Setisation. — Should be examined carefully. Globus (sensation of a ball rising in the throat and choking). Headaches. Neuralgia, specially Infra-mammary Neuralgia, and of Nerve V. Look for Muscular Anaesthesia. Note mental condition and Intelligence. Causation. — Almost exclusively in female sex ; common in early life ; may be very persistent. EPILEPSY. A condition of disease characterized by convulsive paroxysms with loss of consciousness. Look to the general condition of the Nervous System, and signs of Brain Disease. See Convulsions. Note history of onset, frequency of paroxysms, their periodicity and characters, condition in intervals of the paroxysms. Paroxysms. — Note state of consciousness, whether persistent, partially or wholly lost. Note carefully the degree, kind, and range of Spasm, whether Tonic or Clonic. The amount of fixation of respiratory muscles and signs of cyanosis. Whether head is drawn to one side, face distorted, or signs of opisthotonos. Position of eyes and state of pupils. Look for spasms in muscles supplied by cranial nerves, and one-sided, local, or repeated movements. Condition of sphincters. Temperature, pulse, heart. Next passed urine. Starting points. — (1) Hand, usually index finger, thumb, or both ; (2) face, usually near mouth, or tongue, or both ; (•3) foot, usually great toe. Note range of spasm. DISEASES OF THE NERVOUS SYSTEM. ,79 HYSTERIA. The will is defective ; all voluntary movements are usually sluggish and wanting in energy, but movements excited by emotion may be in excess. The condition is most common in young females, and is frequently associated with disordered menstruation. A special character is the liability to attacks of convulsive nature. Disturbance of Sensation is very common, sometimes assuming the form of hemi- ansesthesia, one half the body having lost sensibility, or hypersesthesia. Functional Paralysis is common in this condition ; it may be paraplegic, hemiplegic, or of a single extremity — functional aphonia. Spasm of Muscle, more or less continued, is not uncommon, thus causing contraction of a joint, talipes, or a phantom tumour in the rectus abdominis. Among signs of disturbance of organic nerves are Vomiting- and Angina Pectoris. Causation. — Inherited tendency to neuroses. Disordered men- struation. Depressing mental circumstances. EPILEPSY.* Symptoms of the Attack. — Stage I. Sudden loss of consciousness ; tonic rigidity of muscles ; arrested respiration, often with a cry due to forcing air through closed glottis. Pallor or duskiness. Pupils dilated. Stage II. — Unconsciousness continues ; clonic convulsion ; laboured breathing and foaming ; profuse sweating. Stage III. — Partial return of consciousness and voluntary power. Glasses of Paroxysms. — I. Loss of consciousness without evident spasm. II. — Loss of consciousness with local spasm. III. — Loss of consciousness with general tonic and clonic convulsion. IV. — "Without complete loss of consciousness, convulsion being general or partial (abortive epilepsy). Le petit mal — classes I. and II. * Dr. Reynolds' " System of Medicine." 80 CLI^'ICAL MEDICINE AND CA.SE-TAKIXG. "ETlLEPSY—contimced. FremonitoTy symptoms. — Mental condition, excitability, dul- ness, vertigo, dyssestliesia. Aura epileptica stiictly implies a sensation of wind blowing upon a limb. An aui'a may commence in a limb, or the epigastrium, or in tbe pharynx, in each case passing upwards towards the brain. An aura may commence in an organ of special sense, e.g., the vision of a shape or colom", a "nasty taste," a sound, a smell, a mental sensation. The aura is immediately followed by loss of consciousness. Sequelce. — Pennanent impairment of intelligence and mental capacity. Vertigo. Corii2)lications. — Post - epileptic mania may succeed the paroxysm ; in this state acts of violence or homicide may be unconsciously performed. In a condition after the paroxysms termed " reduction " the patient may perform unconscious acts, e.g.. place things in sti'ange places. - Causation. — Age, sex, psychical causes, and heredity. The commonest antecedents are reflex causes, teething, in- testinal worms ; physical causes, e.g., blows on head, exposure to great heat. Commonest in female sex and from thirteen to sixteen years of age ; may be secondary to other organic changes ; heart disease is common. DISEASES OF THE NERVOUS SYSTEM. 81 CONVULSIONS. EPILEPTIC or Onset. — Sudden, often with an aura. Loss of consciousness usually complete. Prodroma. — Aura epileptica. Asphyxia — Often very complete. i^ace.— Features distorted. Coma. — Usually profound, with stertorous breathing. Con- junetiva insensible. Subsequent state. — Coma ; stu- por ; drowsiness. Subjunc- tival haemorrhages. P'lfi'exia. — May arise if much tonic spasm is present. Sleep. — Common during sleep and when falling asleep. Tongue. — Often bitten. General condition. — Signs of epilepsy. Urine. — Occasionally contains albumen or sugar. HYSTERICAL. Less sudden, with emo- tional disturbance. Loss of consciousness, more pro- tracted, or very apparent. Globus hystericus. Flushed, not asphyxiated. Not distorted. Insensibility complete. Re- flex movements of eye usually continue on touching it. Exhaustion. Temperature normal. Usual during day-time when others are about. Not bitten. Signs of emotional dis- turbance. Copious, limpid, light- coloured, sp. gr. low. G 82 CLINICAL MEDICINE AND CASE-TAKING. CEREBRAL TUMOUR. Special syinptoiiis. — Vomiting, Head-pain, Paralysis of Cranial Nerves, palsy of Special Senses, Optic Nerve changes, Convulsions, Hemiplegia, or other form of Paralysis. Temperature sometimes very higli, witliout any inflammation. Look for Syphilis, Scrofula, Phthisis, Cancer, or new growth in other parts. See Motor Power, and gait in walking. Examine urine for sugar and albumen. Causation. — Syphilis. Scrofulous diathesis leading to tuber- cular mass. Tubercular tendency. Cancer. Tumour may be caseous mass, gumma, glioma, cancer, growth of pituitary body, cyst, hydatid, aneurism, blood-cyst in membranes, exostosis. CEREBRAL MENINGITIS. Xote sj'mptoms, with date and manner of commencement. Special synvptoms. — See general condition of Nervous System, signs of Brain Disease, vomiting, paralysis of Cranial Nerves, intermittent pulse. Look for signs of General Tuberculosis, Phthisis, strumous disease. Ophthalmoscopic examination may show tubercles in the choroid. Note eyes, their movements, strabismus, state of Pupils, photophobia ; general state of nutrition. Take temperature. Examine lungs as to phthisis and recent pneumonia or pleurisy. Examine urine, and note whether it be retained. Look for Head-pain, Vomiting, ear disease, Syphilis. Take temperature. DISEASES OF THE NERVOITS SYSTEM. 83 CEREBRAL TUMOUR. Head-pain may be localized, and permanent, or intermittent with exacerbations. Vertigo is common. Hearing is not commonly palsied. Urine may be saccbarine. Convulsions, partial, clonic, or tonic, not uncommon ; tbey may resemble epilepsy, but usually differ from such attacks as follows : — 1. Irregular in development, with less loss of consciousness and no asphyxia or subsequent coma. 2, Not specially a disease of female sex or early period of life. 3. Less tendency to mental disturbance. 4. No special inheritance of neurosis. 5. Characteristic symptoms of tumour develop. The course of the disease is generally slow. Hemiplegia, if present, usually develops slowly ; if on the right side may be accompanied by aphasia. Preceding death the temperature often rises high. Causation. — Cerebral tumour may cause ventricular efiiision, resembling Hydrocephalus. CEREBRAL MENINGITIS. Onset often insidious ; poorliness and loss of appetite, with head-pain and vomiting. Temperature is a very uncertain sign ; vomiting, though important when present, is frequently absent throughout. Intermittence of the pulse and paralysis of a cranial nerve are very important signs. Tubercles may occur in the choroid, independently of meningitis. Causation. — Miliary Tuberculosis. Disease of ear. Syphilis, Injury to head. Cerebral Tumour. 84 CLINICAL MEDICINE AND CASE-TAKING. CHEONIC HYDROCEPHALTJS. History of family ; of tie pregnancies and labours of the mother. State of the head at birth, or date at which symptoms were first observed. Enquire for Convulsions. iSTote general Motor Power. Sensation. Nutrition ; power to hold head up. Eyesight. Hearing. Intelligence, whether child notices sounds and colours, and plays with toys, or is backward for age. Head. — Is it held well up, well shaped ; its circumference, measurement from ear to ear, over the vertex, and from the nose to the occiput. State of sutui'es and fontanelles, whether patent or ossified. Take tracings of skull with cyrtometer. Eyes, whether of normal direction ; condition of optic nerve. Dentition. Look for signs of Eickets. Look f 01' signs of Defective Development. DISEASES OF THE NERVOUS SYSTEM. 85 CHRONIC HYDROCEPHALUS. Must not be mistaken for the large head of rickets. Con- genital hydrocephalus usually causes difficult labour. Head may be normal at birth, subsequently enlarging. Sometimes accompanied by spina bifida. Tendency to enlargement of the head is progressive. HYDROCEPHALUS. EICKETS. No signs of Rickets, but Signs signs of Brain Disease. Rickets. and symptoms of Head has a tendency to glo- bular shape ; eyes depressed ; often strabismus ; optic nerves atrophied. Cranial bones thin. Cannot hold head up. Para- lysis common, or a contracted limb. Head large, tending to broadness and squareness ; there may be irregular thick- ening of bones. No paralysis, head held up, child playful. Tendency to increase of relative size of head to body, indicated by measurements. Progressive enlargement ; pa- tency of fontanelle continuing. Usually imbecile. Optic atro- phy. As signs of Rickets pass away the relative size of the head less noticeable. May have good power. 86 CLINICAL MEDICINE AND CASE-TAKING. ALCOHOLISM. See Nervous System. See Motor Power. Tendency to tremor ; tongue tremulous, coated, glazed. Muscular weakness and want of muscular co-ordination. See co-ordination of the limbs. Muscular inquietude ; muscular fidgetiness. Look to Muscular Sense (usually diminished). Paralysis, Paraplegia. See signs of disease of Spinal Cord and General Paralysis. Flushing and congestion of the face and eyes. Vomiting, especially in the morning. Conditions of Sleep. Neui-algic pains. Anaemia. Mental disturbance. — Deterioration of mental power, restlessness, loss of memory, hallucinations, delusions. Mental altera- tion, e.g., inaptitude for business, avoidance of friends. Sensation. — Cutaneous sensibility, dyssesthesia, muscse voli- tantes, buzzing in ears, vertigo. Note state of nutrition. <''omplications. — Look for signs of disease of liver, kidneys, vascular system, emphysema. Acne rosacea of nose. Bronchitis. Pneumonia. Delirium and symptoms of delirium tremens. ACUTE ALCOHOLISM. Excessive dose may produce Coma ; breathing stertorous ; breath smelling of alcohol. Appearance of face. Examine urine for albumen and alcohol. Look for signs of general condition of Nervous System. Vomiting. Paralysis. See causes and examination of cases of coma. Examine heart and condition of blood-vessels. Look for — Injury to head. Uraemia. Simple exhaustion. Meningitis. There may be Albuminuria from acute renal congestion. Complications of chronic alcoholism. DISEASES OF THE NERVOUS SYSTEM. 87 ALCOHOLISM. Principally produces nervous symptoms ; affects next the diges- tive system. Nutrition may become much, impaired. In chronic cases, kidneys and liver often become cirrhotic. Vascular system degenerates. Emphysema. Chronic Cases. — In advanced stages, the lower extremities may become unsteady, hands and fingers tremulous, so also the tongue. At first the tremors may be restrained by voluntary eS'ort. Acne rosacea. Diagnosis from — Commencing General Paralysis of Insane, mind depressed. Paralysis Agitans. Plnmbism, with tremor and delirium. Locomotor Ataxy. Paraplegia, from Disease of Cord. Senile Degeneration. Sclerosis. Hysteria. Nervous malaise, from simple dyspepsia. Complications. — Cirrhosis of Liver and Ascites. Chronic Bright's Disease. Atheroma or Degeneration of Arteries and small vessels. Chronic gastritis. Fatty degeneration of heart and liver. ACUTE ALCOHOLISM. Acute symptoms may be due to Delirium Tremens, or to an excessive dose causing toxic efiects, e.g., coma, etc. When drunk — Coma, face livid, breath smelling of alcohol, ten- dency to vomit. Vomits or washings of stomach contain spirit. In very deep coma there may be strabismus. There may be great excitement in place of coma. Cerebral haemorrhage may occur during intoxication. Alcohol in urine. -CLINICAL MEDICINE AND CASE-TAKING. DELIRIUM TREMENS. Delirium, delusions, illusions of Sight and hearing. Vomiting, inability to take food. Intense restlessness. Look for the degenerative changes of chronic alcoholism. Specially examine lungs, urine, heart, and pulse. ISTote muscular condition, general strength, and power of movement. Tremor, subsultus tendinum. Sleep ; degree of con- sciousness. Complicatwiis. — Typhoid State. Subsultus. Coma. Heart failure and pulmonary congestion. Syncope. Albuminuria. Pneumonia. Rapid development of phthisis. INSANITY. 1. Mania. 2. Monomania. 3. Melancholia. 4. Puerperal mania. 5. Moral insanity. 6, Dementia. 7. Idiocy, including imbecility. 8. General Paralysis or Paresis. Causation. — Heredity of primary importance ; enquire back to the third generation in the families of each parent. See also as to collateral relations. Alcoholism. Habits and mode of life. Mental anxiety. Injuries to head. Signs of Insanity. — Talking to self, fantastic dress, refusing food, squandering property, kleptomania, self-injury, violence, delusions, melancholy, incapacity for business, avoiding friends, delirium. See signs of Brain Disease. Illusions of the senses. Sight ; they may be coloured, moving forms. Hearing, smell, taste, touch. The perception of the sense is mistaken, and the impression made is false. Complications. — Phthisis, fragile bones, heart disease, Epilepsy. Attacks of partial coma. Examination of Patients. — Test Motor Power, Pupils, Muscular Sense, Nervous System, Sensation, heart and lungs. DISEASES OF THE NERVOUS SYSTEM. 89 DELIRIUM TREMENS. Usually the efiFect of long-continued drinking, witli dyspepsia and deprivation of food. Commences with disturbance of general condition of the Nervous System ; diminished motor power. Insomnia, night-wandering, and horrors, with delusions, passing on to delirium with violence and suicidal tendency. Delirium may be busy, low muttering, or talkative. Complications. — Sudden syncope during violent struggling in the delirium may lead to sudden death. GENERAL PARALYSIS OF THE INSANE. Characterised by progressive diminution of mental power, followed by paralysis, involving the whole of the muscular system. Pupils show want of symmetry of size, and want of mobility. Mental condition characterized by an exag- gerated feeling of power, extravagant exalted ideas, loss of memory, attacks of excitement and violence. Hallucina- tion ; delusion. Motor Power. — Failure first seen in tongue ; inaccurate articu- lation, fibrillar trembling of the tongue. Pupils unequal. Automatic and reflex actions lessened ; electric contracti- lity of muscles retained. Teeth-grinding. Late in disease, SDhincters lose their control, and there is tendency to choking. Bones may be very brittle. SeTisation. — Cutaneous sensibility usually diminished, and later lost. Muscular Sense lost. Attacks of excitement and violence ; epileptiform convulsions. Face becomes ex- pressionless. Diagnosis from Alcoholism. — Ideas of exaltation ; pupils un- equal : effect of removing alcohol ; paralysis of sphincters. Caicsation. — Inheritance, intemperance ; most common in men. 90 CLINICAL MEDICINE AND CASE-TAKING. PARALYSIS AGITANS. State principal sites of tremor ; hemiplegic type, paraplegic, or confined to one extremity. Examine Motor Power ; whether movements of liead, face, tongue ; if speech be affected. Expression of face- Power to walk ; gait in walking. Note any tendency to involuntary forward or backward move- ment, or dragging of limbs, etc. Ability to perform certain acts, walk, bold out limbs, pick up a pin, or write ; keep specimen of writing. Let bim bold a glass of water, and carry it to bis moutb. Note efi'ect of emotion on tremors. Describe tbe Tremor. SCLEROSIS OF CORD. Examine condition of tbe Motor Power and reflex excitability. Tremors ; see wbetber tbey cease during repose and are increased by voluntary acts. Let patient raise a glass of water to bis moutb, and describe tbe result. Let bim stand and walk ; tben close bis eyes and again perform tbe same acts. Note wbetber tremors are fine or coarse. Note tbe extent of parts affected by tremor ; wbetber bead, trunk, and all tbe extremities are aflected. Examine for Brain Disease. Ankle clonus. DISEASES OF THE NEEVOUS SYSTEM. 91 PAEALYSIS AGITANS. Characterized by muscular tremor, constant even in repose ; muscular power diminislied. Head not tremulous, but may be shaken by movements of the body. Tremor con- sists of jerks, more regular and rapid than in Disseminated Sclerosis. 'No real difficulty of speech, but the utterance is slow and with jerk-like effects. Respiratory movements not affected. In advanced cases muscular rigidity may lead to deformity ; this is specially seen in the hand. There may be a subjective sensation of heat. No Nys- tagmus. Face stiff, expression still. SCLEEOSIS OF CORD. Characterized by muscular tremor, increased in direct pro- portion to the extent of any movement executed. It is only manifested by voluntary movements of some extent, and ceases when the muscles are in complete repose. The oscillatians are larger than in Paralysis Agit'ans, and more resemble the gesticulations of Chorea. Yoluntary acts may be performed despite the tremors. Closing the eyes does not affect the tremors, as in ataxy. Movements are not seen, independent of voluntary efforts, as in chorea. The head is usually affected with tremor ; Nystagmus is common. Patellar tendon reflex is exaggerated in sclerosis, obliterated in Ataxy. 92 CLINICAL MEDICINE AND CASE-TAKING. TETANUS. General condition. — T. = ; sweating. Occurs in the robust rather than in the weak. Special condition of muscular system. — Tonic spasm. Trismus (lock-jaw). Opisthotonos, i.e., body drawn backwards, or emprosthotonos, body drawn forward. Eyes may be retracted from spasm of recti muscles. Face set hard with sardonic grin. Tetanic convulsions frequently repeated. Modes of onset. — Commencing about six days or sooner after injury, may be two to four weeks after injury. Injury may have been overlooked, and the wound healed. The earlier the commencement, the more rapid the case and the more certainly fatal the result. There is a gradual progress of the symptoms. Tonic contraction commences with trismus, extending to throat, back of neck, abdomen. Causation. — Injury, blows, burn ; forcing bodies under skin or under nail. Excited by exposure to cold ; war ; opera- tion. Injury to nerve. Males rather than females. Idiopathic cases due to exposure to wet and cold : this not common. May occur spontaneously in infants within eight days of birth. Diagnosis. — From hysterical opisthotonos. Strychnia poisoning. Hydrophobia. DISEASES OF THE NERVOTJS SYSTEM. 93 TETANUS. STEYCHNIA POISONING.* 1. Period of onset ; not con- nected witli food. 1. Onset soon after food. 2. Stiffness first perceived in jaws ; it tlien progressively extends downwards, attacking the body and limbs, the hands not being commonly affected till the last. Progressive in- vasion, with somewhat gradual increase. 2. Sudden and violent onset of symptoms : commences with shivering, gasping for breath, trembling ; the body and limbs are then simultaneously af- fected, hands clenched, feet curved; at a later date the jaw becomes fixed during a paroxysm. 3. Duration of the case rarely less than twenty-four hours. Seldom fatal in idio- pathic cases. 3. Rarely survive two hours after a fatal dose. 4. Discovery of nux vomica, strychnia, brucin, or other poison in food, vomits, or washincrg of stomach. 4. Absence of wound, ulcer, or traumatism to account for tetanus ; exposure to cold, or special nervous susceptibility. 5. Muscular rigidity almost without intermission. 5. Intervals or remissions of rigidity of muscles. See Taylor on the Poisons. 94 CLINICAL MEDICINE AND CASE-TAKING. LOCOMOTOR ATAXY. Examine condition of the Motor Power ; especially the gait in walking, and co-ordination of the limbs. Let him walk ■with his eyes open, then shut ; let him walk with slight assistance or using a stick. Also test power to keep knee flexed or extended. Test upper extremities, e.g., precision with which he can touch an object, his eye or nose, or execute definite movements. Reflexes, and patellar tendon reflex. Electric Tests. Setisation. — Tactile sensibility ; sense of heat and cold. Sub- jective sensibility ; consciousness of ground in walking ; perverted sensations in lower extremities. Sight, reaction of Pupils, Ophthalmoscopic Appearances. Examine the joints and skin. Look for signs of Disease of Cord. Temporary defects of third nerve common. Bowels and action of bladder sluggish. This disease is often associated with Syphilis. Occasionally gastric crises or attacks of vomiting. DISEASES OF THE NERVOUS SYSTEM. 95 LOCOMOTOR ATAXY. Characterized by difficulty in walking, especially with the eyes shut ; there being no motor paralysis and no loss of nutrition of the lower extremities — patient still having voluntary power to keep the limb flexed or extended with good force. Commonest in males, and at ages thirty-five to fifty years. In walking there is exaggeration of the movements ; the feet are lifted too high and the heel brought suddenly down. The lower extremities are the most afi'ected, but there may be want of co-ordination of the upper extremities also. Electric irritability not im- paired. Patellar tendon reflex obliterated more or less completely. In early stages "lightning-pains" in legs and back are usual ; they may last for years and cause much distress. Pupils usually small, inactive to light (vaso-motor palsy) ; contraction for near accommodation intact, i.e., ciliary muscle sound — ^it is supplied by Nerve III. ; ptosis some- times. The optic nerves sometimes become white from atrophy. Large joints may be the seat of efiusion and chronic absorption of the cartilages. It is distinguished from disseminated sclerosis by the marked increase of symptoms produced by closing the eyes ; this does not so modify the rhythmic jerks of sclerosis. Perforating ulcer of foot ; deafness from atrophy of nerve — some- times found. Urine may be retained. 96 CLINICAL MEDICINE AND CASE-TAKING. INFANTILE PARALYSIS. History. — General condition of healtli. Look specially for Eickets. Test general strength of motor power. State whieli extremity is affected ; note its state of nutrition. Examine tlie separate muscles. Test reflex action and sensation. Electric Tests. Observe temperature of the paralysed limb, and the condition of the skin. Upper extremity. — Can he move the fingers separately ? point with index and little fingers, etc. ? Movement of wrist ; power of pronation and supination ; hold out the limb from the shoulder ; put his hand to back of his head. Measure length and circumference, and compare with opposite side. Lower extremity. — Can child walk, stand, move toes, flex ankle and knee, or hold out the limb 1 When sitting down can he get up ? Catisation. — Age six months to six years. Equally in both sexes. Sequel to exposure to cold or an exanthematous fever. Possibly due to dentition. Rigid contraction frequently causes talipes in leg ; such de- formities much less common in upper extremity. Oc- casionally the bones do not grow in length, and a shortened limb results in after life. DISEASES OF THE NERVOUS SYSTEM. 97 INFANTILE PARALYSIS Occurs during ages from six months to seven years, attacking a certain muscle or gi'oup of muscles. It is unattended by pain or signs of brain disease. It often occurs in children apparently perfectly healthy. The attack of paralysis is never repeated. Invasion. — There maybe premonitory symptoms two or three days, or more ; then the limb may be found paralysed. Such premonitory symptoms may be wholly absent. Onset not usually attended with much distiu'bance of the general condition of the nervous system. Paralysis may be noted without any premonitory symptoms. Course of disease. — Usually the general health remains good. Most of the muscles first paralysed usually regain power in two or three weeks, leaving some muscles, or a single muscle, e.g., deltoid, permanently weakened. In regaining power the order of recovery is the reverse of that seen in paralysis from brain disease ; the finer movements are first regained, e.g., movements of fingers and toes before the wrist and ankles. The muscles permanently paralysed atrophy. The growth of the limb may be checked, espe- cially in the lower extremity. Permanent paralysis may be in one leg only. The palsied limb becomes cold and bluish. Sensation not affected. Reflex excitability impaired or abolished, and electric excitability lost. 98 CLINICAL MEDICINE AND CASE-TAKING. GRAVES' DISEASE (Exophthalmic Goitre). Exophthalmos. — Frequently eyelids cannot close over eyeballs, the eyes remaining open even during sleep. The degree of prominence of either eye is usually equal, but may be more marked on one side. Eyelids tremble on endeavouring to cover eyeball. Eyes appear staring, bright, and glistening. Test sight and optical refraction, and move- ments of eyes. Ophthalmoscopic appearances. Examine pupils. Goitre. — This sign may be absent. Enlargement usually moderate, "with a thrill felt and heemic murmur on auscultation. It is very rarely cystic. Thyroid enlarge- ment usually first seen on the right side. Vascular system. — Throbbing in arteries of neck, and in thyroid. Hfemic bruits over goitre and vessels in neck. Tiolent and frequent action of heart even without exertion. Left ventricle may be dilated. Valvular lesion not very common. Com2JilicaMons. — Dilatation of heart. Asphyxiating attacks. Diarrhoea. Vomiting. Bronchitis. Paraplegia. Head- ache. PLUMBISM. General condition. — Anaemia ; emaciation ; gout. Digestive system. — Attacks of colic and constipation, may be with vomiting, nausea, loss of appetite. Blue line on margin of gums, especially opposite the teeth. Abdomen retracted. Breath foetid. Nervous system. — Paralysis usually of extensors of forearm, attended with atrophy and loss of electrical reaction. Usually paralysis is preceded by attacks of colic Look to the general condition of the Nervous System. Motor Power. Sensation. See Optic Discs. DISEASES OF THE NERVOUS SYSTEM. 99 GRAVES' DISEASE (Exophthalmic Goitre). Mainly cliaracteiized by prominence of the eyeballs. Pulsating goitre. Palpitation. Usually there is Anaemia and disordered menstruation. Emaciation. Mental irritability and want of sleep. See Motor Power. There is a tendencj- to intercurrent attacks of diarrhoea ; appetite capricious. Occasionally enlargement of liver, spleen, and mammae. Frequently there is increase of the symptoms at the menstrual periods. Pupils. — No alteration from the normal ; natural size and activity ; accommodation normal. Ccmsation. — Usually develops in females above age of puberty ; rare in men. May date from a mental shock or period of over-work. It is connected with anaemia and disordered menstruation. PLUMBISM. Characterized by colic, anaemia, blue lines on gums. Paralysis of extensors of forearm, and brain disturbance. Nervous system. — There may be profound disturbance of the brain , Optic neuritis. Delirium. Epileptiform convulsions. General Tremors. Palsy of the extensors of the forearm, principally marked on the right side ; the supinator longus and extensor longior carpi radialis escape palsy. Sensation may be at fault ; numbness in limbs, neuralgia, headache. Complications. — Crout ; Bright's Disease ; optic nerve changes ; paralysis. 100 CLINICAL MEDICINE AND CASE-TAKING. DIPHTHERITIC PARALYSIS. History. — Previous attack of sore-tliroat. Possible source of infection ; evidence as to the diplitlieria. General condition. — W. =. ; nutrition; T. = . Month. — Condition of mucous membrane as indicating previous inflammation. Movement of palate ; fauces ; tongue ; pharynx. Nervous system. — Speech, whether nasal or twangy, under- standable or voiceless. Pain, giddiness. Motor poiver. — Ability to stand and walk ; gait. Eyes, their movements ; vision, accommodation, pupils. Sensation. — Dyssesthesia, with numbness and formication, may precede palsy in limbs. Urine may be albuminous. HERPES ZOSTER. History of illness ; date of onset of symptoms, and of the appearance of rash. Enquire as to recent use of arsenic. Look to general condition, debility. Anaemia, etc. Look for signs of Neuralgia, condition of skin at seat of pain, sensibility, subjective pain, etc, tenderness, tender points along the course of the nerve supplying area afl'ected. Note any nutritional effects on parts affected, ulceration, scars (with Nerve V. see Iritis) ; note subsequent state of Sensation. DISEASES OF THE NERVOUS SYSTEM. 101 DIPHTHERITIC PARALYSIS. Histm^y. — Palsy follows the sore-throat in two to six weeks. Primary illness rarely attended with laryngitis. Complains usually as to motor power, sight, speech, deglutition. P. C. — Area of muscular weakness may be limited to fauces and accommodation of eyes. The limbs, if much weakened, emaciate proportionally. Respiratory muscles may be involved. Palsy is usually symmetrical ; lower extremities often palsied more than upper. Eye -muscles, and tongue and face may be palsied. Prognosis. — Cases usually recover. Danger from heart failure, choking, paralysis of respirator}'' muscles. HERPES ZOSTER. Commonly occurs in young subjects ; it has been noted as common in persons taking arsenic. The disease does not return. Pain precedes the eruption ; it may be severe and last for days. The rash is vesicular, vesicles appearing along the area of a cutaneous nerve ; the vesicles contain a clear watery fluid, and may have inflamed bases. The patches seldom cross the median line, Vesicles dry up and scab ; in debilitated subjects ulceration may follow. 102 CLINICAL MEDICIXE AND CA.SE-TAKINU. DISEASES OF THE VASCULAR SYSTEM. HEART— PHYSICAL EXAMINATION. riis]3ectlon. — See front of cliest. Look for and define apex- beat ; it should be seen in iiftli space an inch below, and internal to, left nipple. Look for other sites of pulsation. Pulsation of left auricle may be seen in third space. Palimtion. — Feel the general force of the cardiac impulse, indicating strong or weak action, Hypertrophy or Dila- tation. Determine area of impulse and site of apex-beat. Search for a thrill, especially towards apex ; feel first with tips of fingers, afterwards mth ends of metacarpal bones. Look for friction fremitus. See pericarditis. See Displacement of Heart. Auscultation. — Listen for 1st and 2nd sounds ; each should be clear "lub-dub. " 1st Sound. — Systolic, coinciding Avith the impulse. Loudest towards apex ; to be traced upwards to the base, towards epigastrium and to axilla. Note character of sounds, sharp, clear, feeble, dull, prolonged, or short, or much resembling 2nd sound (tic-tac). Accompanying bruits are termed systolic. 2nd Sound. — Diastolic, coinciding Avith subsidence of cardiac impulse. Loudest, at level of second costal car- tilage ; aortic valves to the right side (aortic cartilage), pulmonary valves to the left (pulmonary cartilage). Trace the sound to the apex. The whole 2nd sound may be accentuated, or either the aortic or pulmonary only. It may be reduplicated. Accompanying bruits are termed diastolic. Cardiac Mimnurs, — The fact of a cardiac mm'mur being decided, determine its periodicity — systolic, diastolic, or presystolic ; the site of maximum intensity ; and relative conductivity in various directions, towards base or apex, to axilla or along sternum, or along the vessels at the base. Observe if audible by spine or at angle of left scapula. Character of murmurs — plain bellows sound, musical, rasping. DISEASES OF THE VASCULAR SYSTEM. 103 HEART— PHYSICAL EXAMINATION. liispcction. — May detect a diffused wave of impulse, e.g., Pericarditis. Hypertropliied left auricle may be seen pulsating in mitral stenosis or contraction of left lung. Abnormal site of pulsation from Aneurism, usually in right third space. See bulging of precordium. Palpation. — Pulsation may be detected in epigastrium in dila- tation. Thrill systolic over aortic cartilage (second right) in aortic stenosis or aneurism ; at apex in mitral regurgita- tion. A diastolic thrill in base at aortic regui'gitation ; at apex just before the systole in mitral stenosis. Strong heaving impulse with hypertrophy. Auscultation. — Determine if heart's sounds are healthy and in due rhythm ; if accompanied b}^, or replaced by, abnormal sounds (bruits or murmurs) which are generally due to pathological conditions of the valves. jSTote they may be due to Anaemia or Aneurism. 1st Sound. — Indicates the muscular condition of the heart, and how it is working ; strong in Hypertrophy, weak in degeneration of the walls. It may be reduplicated ; may be masked by Emphysema. Ansemic bruit at base common. 2nd Sound. — Due to closure of semilunar valves, aortic and pulmonary ; each should be examined separately. Pulmonary 2nd sound not often accompanied by a bruit unless from ansemia ; it is accentuated in recent pulmonary congestion, as from recent mitral regm'gitation. Aortic 2nd sound accentuated in obstructed arterial (systemic) circulation, as in Bright' s Disease. Cardiac Murmurs. — If the normal heart's sounds are heard, and the other physical signs and the pulse are healthy, we may conclude that the heart is healthy. If a bruit be heard, look for all the Signs of Heart Disease and the presence or history of some cause likely to produce val- vular defects. If there be no other proof of heart disease than the bruit, look for signs of Anaemia and ansemic bruits. The character of murmurs often changes. 104 CLINICAL MEDICINE AND CASE-TAKING. HEART— PHYSICAL EXAMINATION. Percussion. — Detennine and mark out the area of relative and absolute precordial dulness. In health it extends from about the third left cartilage to the apex-beat, being limited below by the line of the liver, and not crossing the median line. Area of dulness may be diminished by atrophy of the heart, as in old age, or heart may be overlapped by Emphysema of the lungs. The area may be increased by pericardial effusion as a triangle, larger than the normal area, with its apex towards the top of the sternum. PULSE. Usually felt in radial artery ; it may be examined in any superficial artery. 1. Frequency. — Frequent or infrequent refers to the number of 'pulsations per minute. P. = 2. Quick or slotv. — Refers' to the time occupied by each beat, not including the interval between it and its successor. 3. Bhythm. — Regular or irregular implies the order of succession. Intermittent, the occasional dropping of a beat. 4. Large or small. — Refers to the degree of dilatation of the artery. 5. Jerking or collapsing. — Full, rising quickly and falling suddenly. 6. Tension. — Soft or hard. Felt by the fingers and measured by the force required to extinguish the pulse by pressure. 7. Dicrotous. — The wave is double-headed and the pulse soft. 8. Locomotor. — When the artery is seen to _'travel like a snake under the skin. State of arteries. — Examine radial, brachial, femoral, dorsalis pedis, temporal, etc. The artery as a piece of tissue may be hard or soft, irregular on the surface, dilated, etc. DISEASES OF THE VASCULAR SYSTEM. 105 HEART— PHYSICAL EXAMINATION. Percussion. — H}^erti'opliy of right ventricle increases the width of the area of duhiess, so that it may reach to the right of the median line. Hypertrophy of the left ventricle extends the dulness ontwards and downwards. Abnormal areas of dulness adjoining the heart may be due to Consolidation of Lung, mediastinal tumour, or Aneurism. PULSE. May indicate the condition of the cavities of the heart and valves, and the state of the nervous system. 1. Frequency. — High in fever and in mental excitement ; in disease of the valves and walls of the heart ; in Graves' Disease. 2. QuicTcness. — Chiefly affected by conditions of the nervous system. 3. Hhythm. — Irregularity may depend upon valvular lesions, especially mitral disease, or on the state of the muscular walls of the heart; bra\n disease, e.g., Meningitis; reflex causes, e.g., dyspepsia. 4. Large or small. — Depends upon strength of the left ventricle and condition of valves. It may be small in mitral disease or depressed innervation. 5. Jerking. — In aortic regurgitation with hypertrophy of left ventricle. This character may be less marked if mitral disease coexist. 6. Tension. — High in Chronic Bright's Disease, and in the cold stage of ague. Low in Typhoid State and conditions of adynamia. 7. Dicrotous. — In fevers, especially in the typhoid state. 8. Locomotor. — Indicates a hard, thickened, or Atheromatous Artery, or an h}'pertrophied left ventricle. State of Arteries. — Rigid, tortuous, and rough upon the surface in atheroma. See Vessels, Disease of. 106 CLINICAL MEDICINE AND CASE-TAKING. PASSIVE (Cardiac) CONGESTION. Starting from an obstructed circulation on tlie left side of the lieart, e.g., mitral obstruction. Fulmonary veins overfull (open into left auricle) ; receive blood from pulmonary capillaries and some of the bronchial capillaries. Bronchial capillaries overfull ; hence tendency to Bronchitis. Pulmonary capillaries overfull; hence Pulmonary (Edema, i.e., effusion into air vesicles. PulmoTiary artery (leading from right ventricle) conveys blood to the overfull pulmonary capillaries ; hence tension rises in the pulmonary artery, and pulmonary 2nd sound ma^ be accentuated. Right ventricle (drives blood into the pulmonary artery, which is overfull). It becomes over-distended and dilated ; this may lead to Tricuspid Regurgitation. Eight auricle (drives blood into the right ventricle, which is overfull). It receives blood from superior and inferior venae cavse and bronchial veins. Superior vena cava receives blood from bronchial veins; these carry blood from bronchial capillaries (which also partly empty into pulmonary veins) ; hence Bronchitis, The bronchial veins also receive blood from the pleura ; hence Hydrothorax. Jugular veins, and the veins of the head and upper extremities, send their blood to the superior cava ; hence Cyanosis of the Face, jugulars standing out in the neck, Congestion of the Brain, (Edema of the upper extremities. If there be tricuspid incompetence, jugulars may be seen and felt pulsating. [Continued next page. DISEASES OF THE YASCULAK, SYSTEM. 107 PASSIVE (Cardiac) CONGESTION. Inferior vena cava receives blood from tlie hejKiiic vein ; hence congestion of intra-lobiilar veins and hepatic capillaries in the lobules causes Enlargement of the Liver and Jaundice, also obstruction to the outflow from the vena port», and congestions of the vessels emptying into the j^ortal system, viz., gastiic, splenic, intestinal, hemorrhoidal ; hence Spleen large. Ascites, Hsematemesis, or Melaena. Renal veins (branches of the inferior cava) receive the veins which collect blood from the capillary plexus sur- rounding the uriniferous tubes ; this plexus becomes primarily cor<5ested, and as it receives blood from the aft'erent vessels of the Malpighian tufts, these capillaries become secondarily congested, leading to Scanty Secretion of Urine and Albuminuria. Iliac and femoral veins return blood from the lower extremities, and their over-fulness leads to capillary con- gestion and (Edema of the Feet, the pressure being the greatest in the most dependent set of capillaries. IMPORTANT ANASTOMOSES. In portal obstruction, anastomosis of inferior haemorrhoidal veins of the internal iliac with branches of the inferior mesenteric of the portal system. In portal obstruction, blood flows from intestines through the rectum to the internal iliac veins. Piles result. In obstruction of inferior {a\idiOViiinal) vejia cava, e.g., by pressure of a growth or tumom*, anastomosis of epigastric veins of the iliacs with mammary branches of superior cava. Enlarged veins on abdominal walls common in ascites. Radial a'od ulnar arteries. — When radial pulse is obliterated we may have a retui'n current by deep palmar arch. 108 CLINICAL MEDICINE AND CASE-TAKING. MITRAL EEGTJRGITATION. MITRAL OBSTRUCTION Inspection. — Apex - beat dis- placed outwards and down- wards ; impulse diffused. Eight ventricle probably dilated. Pulsation of hypertro- pbied left auricle sometimes seen in third left interspace. Right ventricle probably dilated. Palpation. — Right ventricle usually hypertrophied or dilated. Apex-beat displaced outwards and downwards. Pulse frequent, small, ir- regular. Systolic thrill at apex. Heart's action may be irregular. Right ventricle hypertro- phied. Thrill at apex jusb preceding impulse. Pulse small. Auscultation. — Systolic bruit at apex conducted well into axilla, also heard at angle of left scapula. Pulmonary 2nd sound accentuated. Presystolic bruit at apex. Pulmonary 2nd sound accent- uated from increased tension in pulmonary artery. Aortic 2nd sound feeble at apex. Bruit almost localized to apex-beat. Percussion. — Dilatation or hy- pertrophy of right ventricle. Left auricle and right side of heart hypertrophied. Left ventricle not hypertro- phied. DISEASES OF THE VASCULAR SYSTEM, 109 AORTIC REGURGITATION. AORTIC OBSTRUCTION, Jnspection. — Left ventricle Hy- pertrophied ; apex-beat dis- placed outwards and down- wards ; much precordial impulse seen. Pulse seen locomotor. Left ventricle hypertro- phied, but less dilated than with, regurgitation. JPalpation. — Thrill diastolic, distinct afc base ; great hy- pertrophy of left ventricle, precordium thrust forward at systole, etc. Pulse full and Collapsing. Thrill systolic over aortic valves. Signs of hypertro- phy ; impulse strong, heav- ing. Pulse small or not abnor- mal. Auscultation. — Diastolic bruit at aortic cartilage and con- ducted down left side of sternum. ■Co-existing Mitral disease common. Systolic bruit over aorfcic cartilage conducted to right sterno-clavicular joint. Exclude Anaemic Bruit. Percussion. — Area of dulness increased downwards and outwards, from hypertrophj'- of left ventricle. 110 CLINICAL MEDICINE AND CASE-TAKING, HYPERTROPHY OF HEART. Insijection. — Heart's impulse may loe seen over an extended precordial area, shaking and thrusting forward the chest- walls. Apex-beat displaced, usualh^ outwards and down- wards. In children the cardiac area may be bulged forward. Palpation. — Shock of heart against chest- wall very distinct, raising the hand or stethoscope. Impulse felt in several interspaces. Epigastric pulsation if right ventricle is hypertrophied. Pulse full and strong in proportion to the hyperti'ophy. Aiiscidtatioii. — Fu'st sound prolonged, dull, strong. Aortic 2nd sound intensified. ' A-ofe diagnosis from pericardial effusion by intensity of 1st sound coinciding ^Yith increased area of dulness. Percussion. — Area of dulness. Left ventricle enlarged down- wards and outwards, and may extend a little upwards. Right ventricle enlarged laterally, and may extend to right of sternum. HYPERTROPHY AND DILATATION. Causation — Obstructions in tlw jjidmonary circulation {right heart affected). — Emphysema. Chi'onic bronchitis. Chronic pleurisy. Adhesions of lung preventing expansion. Obstructions in tlic aortic circulation {ijrinutrily aifecting left side). — Arterial disease. Chronic Bright's Disease, ^^-ith thickening of small arteries. General plethora. Repeated pregnancies. Causes originating in or about the heart. — Primary dilatation, -e.g., after fevers, in Anaemia, Vahoilar disease and stenosis of the outlets. Adherent pericardium. Ex- cessive exercise. Displacements of the Heart. Mal- formations. Emotional disturbance long continued. Fatty or other form of degeneration. DISEASES OF THE VASCULAR SYSTEM. Ill DILATATION OF HEART. Inspection. — Impulse diffused, not bulging or shaking walls of chest. If right ventricle is dilated, epigastiic pulsation may be seen, and Tricuspid Eegurgitation may lead to pulsation in jugular veins. Cyanosis and dropsy common. Palpaticm. — Impulse diffused ; it may be heaving if ventricles are hypertrophied, or feeble if walls are degenerate. Impulse may be masked by emphysematous lung over- lapping the heart. Pulse weak, especially if walls of ventricle are degenerate. Auscultation. — If walls of heart are degenerate, 1st sound feeble, short, and much resembling 2nd sound. HYPERTROPHY AND DILATATION. Dilatation of either ventricle may exist without much compen- sative hypertrophy ; perhaps this is most common on the right side. A dilated and hypertrophied heart may be capable of carrying on the circulation so perfectly as to compensate for a valvular lesion, but when degeneration of the heart-walls follows, then signs of Cardiac Congestion are apt to supervene. Very great hyperti'ophy of the left ventricle without any bruit or valvular lesion is common with Granular Contracted Kidneys. The cardiac impulse and area of dulness are often masked by emphysema of the lungs ; but still, with hyperti'ophy the pulse is strong. Examine heart, lungs, urine. 112 CLINICAL MEDICINE AND CASE-TAKING. CARDIAC DISPLACEMENTS. Pleuritic Effusion, pushing the heart to the opposite side ; .subsequent contiaction of lung may draw it to the side affected. Cirrhosis of lung, or other form of contraction, drawing heart to side affected. Cancer of lung, if diffused, dragging it to side affected by conti'acting. Mediastinal tumour, cancer. Aneurism, glandular, pushing heart aside. Abdominal Tumour, hepatic, ovarian, etc., pressing up diaphragm may displace heart. VALVULAR DISEASE. Causation.- — Rheumatism, atheroma, rupture of valves, scarlet fever. Syphilis, Alcoholism, muscular over-strain, con- genital heart defect. HEART DISEASE. General symptoms. — Seldom attended with pain, unless Angina. General condition. — Anaemia, mal -nutrition, (Edema, haemor- rhages, faintness, languor. Digestion. — Dyspepsia, Jaundice, Ascites, Liver large. Vascular system. — Palpitation. Irregularity of heart's action. Haemorrhages. Cyanosis. See Passive (Cardiac) Conges- tion. Dropsy. Embolism. Irregular pidse, feeble, etc. Over-fulness of veins. Nervous system. — Distui'bance of general condition of Nervous System. Insomnia. Vertigo, Headache, Chorea, Convul- sions, Paralysis, Angina Pectoris. Respiratory system. — Orthopncea. Dyspncea, especially on exertion. Respirations frequent. Bronchitis, Emphysema, Cough. Urine. — Scanty, with deposit of lithates. Sp. gr. high. May contain albumen or blood. DISEASES OF THE VASCULAR SYSTEM. Hi CARDIAC BISPLACEMENTS. May be diagnosed by palpation and percussion principally. The heart may be raised by pericardial eflusion. Apex- beat may be displaced by cardiac Hypertrophy or Dila- tation. Displacement may cause cardiac dyspnoea, etc., e.g., in cases of sudden pleuritic effusion. VALVULAR DISEASE. Causation. — Rheumatism usually attacks the mitral valve, and may spread to the aortic. Atheroma spreads from the aorta to the valves. HEART DISEASE. Enquire for signs and symptoms of heart disease, then make a careful physical examination. Listen for the normal sounds, and bruits accompanying or replacing them. Look for signs of Hypertrophy or Dilatation. If a bruit is heard, look for signs of anaemia. Note state of pulse and respiratory system. Examine arteries. Valvular lesions are often combined, e.g., aortic regurgitation and mitral regurgitation coexisting, etc. Many symptoms result from passive congestion, e.g., oedema, cyanosis, pulmonary oedema, bronchitis, hydrothorax, haemoptysis, large spleen, enlargement of liver, jaundice, ascites, Albuminuria, congestion of brain. These symptoms then vary with the heart's condition. 114 CLINICAL MEDICINE AND CASE-TAKING. PALPITATION. FTTNCTIONAL. Disturbance of the general condition of the Nervous System. Excessive smoking, or use of tea and coffee. Often relieved by exercise. Frequent in recumbent pos- ture. Mostly in hysterical women. Attacks intermittent, as causes producing them vary, e.g., dyspepsia, menstruation. Between attacks heart and pulse natural. Often accompanied by neur- algic pains. ORGANIC. Physical signs of disease of walls of heart or its valves. Accompanying general Signs of Heart Disease. Excited by exertion, re- lieved b}'' rest. Mostly while at work. Mostly in men who labour. Coincide with the amount of exercise, but may be ex- cited by emotion. In intervals signs of heart disease may be best detected. Xot often accompanied by distinct pain, but there may be attacks of Angina Pec- toris. In attack, pulse small and irretfular. Disease of walls of heart, vessels ; Aneurism. In attacks face may be flushed, throbbing in ears, tinnitas aurium. Gout ; masturbation ; want of sleep ; Graves' Disease. Cmisation. — Heart disease ; Dilated Heart ; Hysteria; hyper- trophied heart with degeneration. Reflex uterine ; dyspepsia. Exawtine heart, its sounds, impulse, regularity. Look for Vascular Degeneration. DISEASES OF THE VASCULAE, SYSTEM. 115 ANGINA PECTORIS. Note exciting causes of paroxysms, the times and circumstances under which they occur. In the paroxysm, note position and attitude of patient, facial expression, ability to speak or othermse, state of skin ; Pulse, its frequency and characters ; action of heart during attack. Note state of respiration. Examine urine passed after attack. Examine heart and vessels in the intervals of the paroxysms. It is characterized by sudden paroxysms of intense suffering, with the sense of impending death, or a sense of want of air, burning pain in chest, or sense of constriction, pain radiating from the chest down the left arm. In paroxysms there may be profuse sweating, face pale, occasionally flushed, palpitation, subsequent exhaustion. Pulse may be small and weak, or strong and not frequent. Causation. — Organic disease of heart, walls, or valves. Disease of vessels. See Signs of Heart Disease, especially hyper- trophy and dilatation. Atheroma of arteries. Syphilis, Aneurism, over-exertion. Alcoholism, Gout, Hysteria. Reflex exciting causes, e.g., dyspepsia, uterine derange- ment, mental excitement. 116 CLINICAL MEDICINE AND CASE-TAKING. PERICARDITIS. Precordial pain and tenderness. Dyspnoea, especially in upright posture. Tendency to syncope. Palpitation. Pain on swallowing. Fever. liispection. — A diffused wavy impulse ma}^ be seen. In young subjects the precordial region may bulge. Palpation. — Precordial fremitus may be felt, especially if patient sit or stand up. Apex-beat may be elevated and slightly displaced outwards. Tenderness on upward pressm'e fi'om epigastrium. Pulse feeble, irregular, inter- mittent. Auscultation. — Friction sound not suspended on holding the breath ; it may be altered by pressure — " to-and-fro, " or only systolic ; a brush or hard grating sound. Describe the heart's sounds heard as well as these adventitious sounds. Percussion. — Tenderness. Enlarged area of cardiac dulness ex- tending as a triangle, apex upwards, to second rib, and even passing to right of sternum. Area of dulness may pass outside apex-beat. Ga.usation. — Rheumatism. Bright's Disease. Scarlet Fever. Erysipelas and other fevers. Pyaemia. Cold. Neighbour- ing abscess or cancer, etc. DISEASES OF THE VASCULAE SYSTEM. 117 PEEICAEDITIS. May coexist with other inflammatory conditions, e.g., Pneu- monia, Pleurisy. If valvular disease coexist there may be orthopnoea. The cesophagus is in close relation to the pericardium. Inspection. — Extended wave of impulse may be due to Aneurism or Retracted Lung exposing the left auricle. Palpation. — Fremitus may be absent in recumbent posture, if effusion be excessive or purulent. Diffused impulse may be mistaken for cardiac dilatation ; it is weaker than in cardiac Hypertrophy. Auscultation. — Friction may be inaudible with excessive serous effusion or with pus ; it ceases when adhesion occurs. Friction of a roughened pleura moved by heart may be mistaken for pericarditis. Endocardial murmurs ma}' accompany those exocardial. Percussion. — Extended area of dulness may suggest hyper- trophy, but in pericardial effusion the sounds are indistinct. Extended dulness, apparently cardiac, may be due to solidification of the left lung. Diagnosis. — From endocardial murmurs by the friction being felt, and being heard as localized and not specially conducted in certain directions. Fremitus may be altered by pressure of the stethoscope on the chest, especially in young subjects. The friction is heard as superficial and more grating than an endocardial murmiu'. 118 CLINICAL MEDICINE AND CASE-TAKING. CONGENITAL DEFECTS OE THE HEART. Among the signs of malformation or congenital defects of tlie heart and vessels there may be cyanosis, clubbed lingers and toes, low temperature, a general want of development, or some special deformity of the mouth, ears, fingers, etc. Enquu'e as to the history of the mother's pregnancy. Make physical examination of the heart ; there may be hypertrophy of one or both ventricles in various forms of malformation. Tricuspid Constriction may result from fcetal endocarditis. See Developmental Defects. TRICUSPID REGURGITATION. Systolic murmur at the lower part of the sternum to its right side or near the ensiform cartilage, not conducted to the aorta. Examine for other valvular lesions and Emphy- sema. As a primary disease it is rare, and usually congenital. Examine jugulars for venous pulse, and see if they refill from below when emptied. DISEASES or THE VASCULAR SYSTEM. 119 CONGENITAL DEFECTS OF THE HEART. Some conditions are incompatible with life. The conditions most commonly met with are communications between the ventricles through the septum ; these may be accompanied by a systolic bruit heard near the base of the heart, not conducted into the arteries. Cyanosis is not a necessary accompaniment ; the bruit may not be constant. Patent foramen ovale but rarely produces a murmur ; it is often accompanied by a contracted pulmonary orifice, which produces a systolic murmur at the base. TRICUSPID REGURGITATION. Usually secondary to mitral disease or emphysema ; the right ventricle is then hypertrophied. At systole regurgitation takes place into the vena cava, causing venous pulse in the neck, the pulsation being perceptible to sight and touch. It may be temporary from over- distension of right ventricle during an attack of Bronchitis. 120 CLINICAL MEDICINE AND CASE-TAKING. THORACIC ANEURISM. Physical signs. — Pulsation, wlien the aneurism points against the chest-wall, most usually about third right rib. The chest-walls may be bulged, the ribs absorbed, and the tumour become prominent. Impulse may be felt with a thrill at same point. The heart may be displaced, but is not usually hypertrophied. The sternum or chest-walls may be heaved up without any prominent tumour. A systolic or double bruit may be heard at seat of impulse, but not necessarily so. Heart-sounds may be heard as distinctly over the aneurism as over the heart itself. The aortic valves may be incompetent. Dulness over chest in an abnormal situation mthout signs of lung consolidation. Pressure signs. — Pressure on one lung or bronchus causes dyspncea on exertion, and loss of respiratory murmur over the lung compressed. Haemoptysis, or ulceration of bronchus or ti-achea. Dysphagia from pressure on the oesophagus. Constant pain in back. Pressure on sub- clavian artery causing unequal pulses in radials. Pressure on veins causing oedema and enlargement of superficial veins. Irritation of sympathetic nerve in chest causing dilatation of the corresponding Pupil, or its contraction if nerve is paralysed. Paralysis of one recurrent laryngeal nerve causing paralysis of the corresponding vocal cord, cough, laryngeal stridor, and metallic-toned voice. {Note — • the left nerve turns round the arch of aorta, the right round the innominate artery. ) Pressure on trachea causes spasmodic cough, often with tracheal respiration, heard over sternum and vertebrae. DISEASES OF THE VASCULAR SYSTEM. 121 THORACIC ANEURISM. Prominent symptoms. — Pulsation on the surface of the chest, vdih dulness at a point remote from cardiac impulse ; dyspnoea on exertion ; stridulous laryngeal breathing from paralysis of one vocal cord ; pressure signs in thorax ; Angina Pectoris ; Hsemoptysis. CoAisatio^n. — Atheroma of aorta. Syphilitic arteritis. Strains and injuries. Most common in men and in middle and later life. See Vessels, Disease of. Diagnosis from chronic laryngitis ; cough loud and paroxys- mal with a ringing sound, laryngoscope showing palsy of one cord with no other disease. The pulmonary artery or left auricle may be uncovered by retraction of the left lung, and abnormal pulsation on the surface may result, with an enlarged area of dulness. A cancerous tumour may be pulsatile. Earely, an empyema may pulsate. Course of disease. — The tendency of an aneurism is to increase in si2e. If blood is pumped into the sac at a pressure of one ounce to the square inch, that amount of pressure is exerted on each square inch of the aneurism. Pressure may cause absorption of vertebrae, ribs, sternum. The sac may burst into the pleura, lungs, pericardium, oesophagus, or externally, etc. Signs of rujjture. — Sudden or rapidly increasing dyspnoea. Paleness. 122 CLINICAL MEDICINE AND CASE-TAKING. VESSELS, DISEASE OF. Look for Anaemia, Heart Disease, (Edema, Bright's Disease, cutaneous hsemorrliages, loss of elasticity of skin, SypMlis, Gout, Alcoholism, Epistaxis. Arteries. — Examine all the superficial arteries, e.g., radials, brachials, temporals, femorals, dorsales pedis, etc. Feel the condition of the vessels, whether soft or hard, rough upon the surface, rigid, calcareous, locomotor, tortuous, snake- like. Embolism may occlude any artery in the limbs : in spleen, causes its enlargement A\ith tenderness ; in kidney, temporary albuminmia or htematuria ; in brain, hemi- plegia. Retinal artery may be blocked. Veins. — Most often diseased in lower exti-emities ; may be enlarged, showing situation of valves. Varicose veins may become hard from occurrence of thrombosis, the clot organizing and becoming hard and cord-like ; then ulcer of the skin may result. Phlebitis may occur during fevers, e.g., enteric, scarlet fever, erysipelas, the vein becoming tender, swollen, hard, cord-like. There may be cedema and subsequent abscess. Look for gout, pressure on the vein, cancer, phthisis, or other cause of great debility. Aneemia. Capillaries. — Often seen dilated over malar bones in persons exposed to the weather ; in Cirrhosis of the Liver, chronic Bright's disease, heart disease, alcoholism. DISEASES OF THE VASCULAR SYSTEM. 123 VESSELS, DISEASE OF. Often coexists with general degeneration of the tissues of the body, and especially of the kidneys. Arteries. — Disease may be senile degeneration or due to local injury or strain, atheroma, gout, rheumatism, syphilis, alcoholism. There may result Aneurism, aortic incom- petency, thrombus, embolism, gangrene, cerebral haemor- rhage. Arteritis ; if diseased, specially liable to give way when heart is hypertrophied, as with Granular Kidney. It is apt to lead to vertigo, hemiplegia. Embolism may start from a diseased valve or point of atheromatous artery. Onset of symptoms often sudden ; it may obstruct any systemic artery ; it often occurs in brain. Veins. — Staining of the legs in course of veins may result from constantly sitting before the fire. Varicose veins may result from long standing or constipation. Phlegmasia dolens after confinement. Loss of fat from the legs removes their natural support. Phlebitis, or inflammation of a vein. The clot may break down and lead to pyaemia. It may be detached and carried to the right side of the heart, and plug the pulmonary artery or a branch, causing dyspncea, haemoptysis from collateral hypersemia, syncope from arrest of circulation in the right heart, and sudden death. It may occur deep in a limb. Capillaries. — Chronic capillary congestion in a limb often seen when the nervous centres are diseased, e.g., paralysis, idiocy, etc. ; hands blue and cold ; chilblains. 124 CLINICAL MEDICINE AND CASE-TAKING. DISEASES OF THE EESPIRATOEY SYSTEM. CLINICAL REGIONS OF THE CHEST.* Supra-clavicular. — From outer end of clavicle to ti*achea. Clavicular. — Behind inner half of cla^"icle. Infro.- clavicular. — From clavicle to lower border of third rib, and outwards to a vertical line from the acromial angle which divides the anterior from the lateral regions. Mammary. — Extends to lower border of sixth rib. The nipple is usually" over the fourth rib. Infra-nianvinafi'y. — Extends to lower margin of the ribs. Lateral regions : Axillo/nj. — From apex of axilla to line con- tinuous with lower border of mammary region, and bounded posteriorly by scapula. Infra-axillary. — Extends down to the margin of the ribs. Upper and loioer scapular regions. — Above and below spine of scapula. Inter -scapular region. — Between inner edge of scapula and spines of dorsal vertebra. Infra-scapmlar region. — From angle of scapula to margin of ribs. Upper sternal. — Extends to lower border of third rib. Lower sternal. — From third rib downwards. * After Dr. Walshe : " Diseases of the Lungs." DISEASES OF THE RESPIRATORY SYSTEM. 125 CLINICAL REGIONS OF THE CHEST. Supra-clavicular. — Contains apex of lung ; this is usually highest on the right side ; also portions of subclavian and carotid arteries, and large veins. Clavicular.- — Lungs, large arteries. Infra-clavicular. — Upper lobe of either lung. Right side, close to sternal border lie the superior cava and part of the arch of aorta. Left side, edge of pulmonary artery, the base of the heart being below. Mammary. — Right side, middle lobe of lung. Left side, pre- cordial area, sloping outwards and downwards to a point about an inch below and internal to nipple. Infra-mammary. — Right side, liver dulness, the lung encroach- ing to a variable extent on full inspiration. Left side, stomach, and inner portion of left lobe of the liver. Spleen rising to sixth rib in lateral region. Lateral regions : Axillary. — Contains upper lobes of the lungs. Infra-axillary. — Lower margins of the lungs sloping down- wards and backwards. Right side, liver ; left side, spleen and stomach. Upper and lower scapular regions. — Contains lungs. Inter-scapular region. — Lungs, main bronchi, and glands, descending aorta, oesophagus. Infra-scapular region. — Lungs down to eleventh rib ; liver lies below this on right side. Left side may be partially occupied below by intestine. Aorta descends along the left inner boundary. Upper sternal. — Contains large vessels ; transverse portion of the arch of aorta. Aortic valves at level of third right cartilage, pulmonary valves to the left. Bifurcation of trachea at level of second rib. Lower ster'nal. — Main portion of right ventricle and a small portion of the left resting upon the diaphragm and liver ; at upper part a small portion of the left lung. 126 CLINICAL MEDICINE AND CASE-TAKING. PHYSICAL EXAMINATION OF THE CHEST. Inspecticrti. — Observe general configuration ; form, especially local or on one side, e.g., bulging or retraction ; observe spine, if straigbt. Cbest movements — thoracic, abdominal. In health, expansive movements are forward and upward. The sternum moves forwards and upwards on inspiration. Specially observe expansive movements in the infra-clavi- cular regions. In calm breathing, abdominal movements are scarcely observable. Observe position of heart's apex- beat, and the condition of the intercostal spaces. PATHOLOGICAL CONDITIONS. Exjxinsion, or bulging, may affect one or both sides ; it may be general over one side or only affect a particular area. Observe intercostal spaces, whether bulged or sunken. Look for position of heart's apex-beat. In all cases carefully compare the corresponding regions on the two sides. Betraction, or depression, may be general over one or both sides of the chest. It may be localized in one side, as in jQatten- ing or retraction in the infra- cla\4cular region or in the axillary regions. Examine spine ; it may be bent to side contracted, with dropping of that shoulder. Contraction in infra-mammary regions common in infants from Rickets and collapse of lung. Chest movements. — Deficient expansion may be bilateral and general, one-sided or local. There may be a permanent condition of expansion, e.g., Pleuritic Effusion, or j)erma- nent Contraction, In women, respiratory movements are principally thoracic. Movements of diaphragm may be restricted by various conditions of the abdomen, e.g., Ascites, ovarian tumour, Abdominal Tumour, Rhythm of the respiratory act. — In health, if the total dui'ation of one movement be taken at 10, inspiratory movement = 5, expiratory 4, pause 1. DISEASES OF THE RESPIRATORY SYSTEM. 127 PHYSICAL EXAMINATION OF THE CHEST. Inspection. — The general fomi should be symmetrical on the two sides, and slightly convex in the infra-clavicular regions. Shoulders should be on the same level, and the spine straight. Specially observe movements, and Signs of Retraction in the infra-clavicular regions. The two sides of chest should be symmetrical, but, in men, muscular development may cause greater fulness on the right side. There may be expansion, or bulging, or retraction, or altered chest movements. Chest may be deformed from Bickets. PATHOLOGICAL CONDITIONS. Expansion, or bulging. — General enlargement of both sides may be due to Emphysema. If one-sided from Pleuritic Effusion or pneumothorax, the heart is then generally displaced. Local bulging may be due to Aneurism, mediastinal tumour, encysted empyema ; in right infra-axillary region from enlargement or tumour of liver. In children, Cardiac Hypertrophy may cause local bulging. Retraction, or depression, implies contraction of the lung corre- sponding, as from consolidation or pleurisy. It may be general in atrophous emphysema. In infra-clavicular regions it is an important indication of Phthisis. Collapse of lung may occur from Laryngeal Disease, and accompanies " pigeon-breast " in rickets. Chest mowmewfe.— Movement may be restricted by the pain of a pleuritic stitch or by pleurodynia ; by ossification of the ribs, or by conditions of the lung and pleura. Deficient movement in the infra-clavicular spaces accompanies con- traction of the apex. In Emphysema vertical movement of the sternum is usually unaccompanied by any forward expansive movement. Rhythm of the respiratory act. — Duration of expiratory movement maybe greater than the inspiratory, e.g., in obstruction to entry of air, in emphysema. Inspiration may be short and abrupt. 128 CLINICAL MEDICINE AND CASE-TAKING. PHYSICAL EXAMINATION OF THE CHEST. Palpation. — Observe movements of tlie cliest, both general and local. Compare the two sides. Determine the intensity of tactile vocal fremitus (T.V.F.) in various situations. A friction fremitus from pleurisy or pericarditis, or from a rlionclius in young subjects, may be detected. Percussion. — Percuss each region of the chest, and determine the boundaries of the heart and liver, height of apices of lungs in neck. If the percussion note varies from the normal, determine the area of this abnormality, and compare with the same region on the other side. Hyper -resonant or tympiccnitic. Cracked-pot sound. — Jerky and with metallic character. Amphoric. — Like the sound of filliping the cheeks tensely distended. AUSCULTATION.* Kote separately inspiration and expiration, their character, re- lative dui-ation, and whether accompanied by adventitious sounds. Auscultate each region of the chest. Normal respiration. — Vesicular murmur ; breezy. Puerile respiration. — Exaggerated in both sounds, increased in intensity, especially the expirator3^ ABNORMAL SOUNDS FROM ALTERED CONDUCTIVITY OF LUNG- TISSUE. Harsh respiration. — Loss of natural softness and breeziness. Expiration increased in duration and in intensity. BroncMal respiration. — A higher degree of harsh respiration. Both inspiration and expiration are altered. Tubular respiration. — Air heard drawn in and puffed back with a metallic character. Cavernoics respiration. — Hollow metallic sound. * These definitions are mostly quoted from Dr. Walshe, op. cit. DISEASES OF THE EESPIEATORY SYSTEM. 129 PHYSICAL EXAMINATION OF THE CHEST. Palpation. — Of great value in detecting local contractions and impairment of niovement. T.V.F. (tactile vocal fremitus) increased (usually) over Solidified Lung and diminished over a Pleuritic Effusion. Percitssion. — In healtli, the sound is resonant, and resistance vibratile over lung. Sound approaches dulness, and resist- ance increases with various degi'ees of consolidation of the lung, or pleuritic effusion. Dulness may be noted on superficial or deep percussion only. Hyjjcr -resonant or Tympanitic. — Over Emphysema or Pneumothorax. Craclced-pot. — Over a vomica ; sometimes in young children without disease. Amphoric. — Yomica. Pneumothorax. AUSCULTATION. Helps to determine the physical condition of the lungs, and the position of their margins. In health, duration of inspi- ratory sound to the expiratory is as 3 : 1 (inspiratory move- ment of chest to expiratory as 5 : 6). Note separately the respiratory murmur and any adventitious sounds. Puerile respiration. — Normal in children. In adults, frequently due to a portion of lung doing extra work (supplemental respiration) on account of neighbouring lung-tissue con- solidated or compressed. ABNORMAL SOUNDS FROM ALTERED CONDUCTIVITY OF LUNG- TISSUE. Harsh respiration. — In moderate degrees of consolidation and in Emphysema. Bronchial respiration. — Indicates slight condensation of lung substance. Tubular respiration. — Perfectly developed over hepatized lung in pneumonia. Cavernous respiration. — Indicates probable cavity from phthisis; dilated bronchus. K 130 CLINICAL MEDICINE AND CASE-TAKING. AUSCULTATION. ADVENTITIOUS SOUNDS. FJionchi. — "Whistling, cooiug, bubbling, crackling sounds. Sonorous rhonchus. — Inspiratory and expiratory usually; sometimes beard without contact "with the chest. It is a snoring sound. Sibilant rhmicJius. — Dry sounding ; high pitched, some- times hissing; in character ; ^yhistling. CrejJitations are crackling rales occurring in successive pufi's, all resembling one another. They may occur with inspiration or expiration. Fine crepitation resembles the sound produced by rubbing hair near the ear ; it occurs on inspu'ation in the first stage of Pneumonia. Pleural friction sound. — Heard only with respiratory move- ments, except that occasionally a lung, roughened at its margin, is moved by the heart. It may be heard on inspi- ration and expiration ; jerky in character ; grating ; like a simple brush ; or a creak like that of new leather. COUGH. Xote character and frequency ; paroxysmal, e.g., Hooping Cougli ; whether occurring in prolonged attacks ; accom- panied by Sputa. Causation. — Bronchitis; lung disease; Phthisis; broncho- pneumonia ; Pleurisy ; Heart Disease ; pressure on air tubes in chest, e.g., Aneurism, mediastinal tumour, en- larged bronchial glands. See hooping cough. Reflex causes ; examine Mouth, fauces, pharynx, Larynx, DISEASES OF THE EESPIEATORY SYSTEM. 131 AUSCULTATION. ADVENTITIOUS SOUNDS. Rhonchi may be greatly altered by a cough ; they may disappear and return, being much less constant than the frictions, which they sometimes resemble. They are characteristic of Bronchitis, and are frequently so loud as to mask all respiratory sounds. The fremitus pro- duced by a rhonchus may commonly be felt in children on palpation. Crepitations may be mistaken for pleuritic friction. Small bubbling crepitations are heard at bases in Pulmonary (Edema. Scattered crepitations are commonly heard at the apices in Phthisis. Crepitati<)ns are sometimes absent till patient has coughed and cleared the bronchus leading to the seat of crepitus. Pleural friction sound. — It is more lasting than a rhonchus, and cannot be coughed away. It indicates a roughened pleura, but may not be heard in Pleurisy on account of Pleuritic Effasion, or the hepatization of lung beneath pleura preventing its movement. COUGH. Xot a necessary accompaniment of lung disease, and often not dependent upon lung disease. Prolonged attacks of coughing sometimes cause so much asphyxia that tem- porary loss of consciousness arises from passive congestion of the brain. 132 CLINICAL MEDICINE AND CASE-TAKING. SPUTUM. Its amount, consistence, whether aerated, colour, mixture of substances, blood, colourless, mixed with blood, streaked with blood, yellowish, white ; frothy, mucilaginous- looking, watery, viscid, grumous ; mucus, purulent, nummulated, in viscid masses. H-a:MOPTYSIS. Causatimi — Valvular disease of left side of heart (pulmonary). Valvular disease of right side of heart (bronchial). Embolism of pulmonary artery from peripheral veins (infarction). Embolism of bronchial artery from left side of heart. Blow on chest. Bronchitis. Plastic bronchitis. Foreign body in trachea. Blood entering the larynx and coughed up. Aneurism bursting into bronchus. Spasmodic Asthma (bronchial). * Emphysema. Asphyxia (bronchial). Scurvy. Htemorrhagic diathesis. Renal disease (vessels diseased). Uraemia (blood changes). Degeneration of tissues and vessels (alcoholic). Phthisis. Cancer of lung. Pneumonia. Abscess of lung. Vicarious menstruation attended with amenorrhcea. After an attack of haemoptysis there may be signs of blood having run down to base of lungs (crejjitations and dulness). It may occur accidentally without organic disease. Hsemorrhage from the throat may be mistaken for haemoptysis. DISEASES OF THE EESPIRATOEY SYSTEM. 133 SPUTUM. Often frotliy water, colourless in early PhtMsis ; later purn- lent, copious, and (when vomicEe have formed) nummulated. Viscid, sticky, golden coloured in Pneumonia, and prune- juice colour if mixed with blood. "White, aerated, frothy in simple bronchitis. Stinking with gangrene of lung, and in some cases of dilated bronchial tubes. Diagnosis of HEMOPTYSIS from HEMATEMESIS. Blood ejected. — Bright, frothy. Dark, clotted, mixed with may be mixed with mucus. food. Acid. Alkaline. Manner of ejection. — Coughed Vomited mixed with food. up, expelled without effort ; Acid. Patient often faints faintness subsequent to ejec- before ejection. tion. No food expelled. Previonitory symptoms. — Cough, Signs of Ulcer or Cancer signs of Phthisis, previous of Stomach, pain with food, specks of blood with expec- epigastric tenderness, mala- toration. ria. Cirrhosis of Liver, Subsequent symptoms. — Subse- Subsequent blood by stool, quent expectoration of mucus usually black, tar-like and blood. matter. Haemoptysis is mostly due to disease of the lungs or heart. It may also be due to blood changes, e.g., ursemia. Care- fully examine heart, lungs, urine. P. = ; T. = ; E. = ; W. = . Enquire as to history of lung disease in patient or his family, also for early deaths in family. General condition of nutrition, etc. Haemoptysis may apparently be sometimes purely accidental in a lung previously healthy, and blood remaining in the lung may set up phthisical changes. 134 CLINICAL MEDICINE AND CASE-TAKING. DYSPNCEA. General condition. — Position of the . patient, orthopncea, cya- nosis, fulness of the veins, (Edema, Anaemia. P. = ; T. = ; E,. = . Xote any stridulous breathing or sign of Laryngitis. Respiratory movements, whether thoracic or abdominal ; if accompanied by collapse of the base of the chest or recession of the epigastrium on inspiration. Ability to speak ; voice. Character of the dyspnoea, con- stant or paroxysmal ; causing much distress ; attended Avitli pain, cough, and expectoration. Increased by exer- tion or occurring on exertion only (probably cardiac). Examine the lungs, heart, urine. Note condition of the cu'culation. Pulse, Vessels. Respiratory muscles, if in a sta-te of over-action, especially the sterno-mastoids. Action of alae nasi. Fixation of the arms to enable chest muscles to act at gi'eater advantage. General condition of the Nervous System. PULMONARY (EDEMA. At base of lungs abundant small bubbling rales. T.Y.F. may be increased or diminished. On percussion resonance diminished and resistance increased. Dyspnoea, Xote position of patient ; signs of Typhoid state. Examine urine, Xote general condition of patient, specially of Nervous System. DISEASES OF THE HESPIEATOEY SYSTEM. 135 DYSPN(EA. Causation — Structural clmnges. — Emphysema; PhtMsis; Pneumo- nia; Bronchitis. (Edema of lungs. Pleuritic Effusion, pneumo-thorax, acute pleurisy. Upward pressiu'e of diaphragm from ascites. Conditions of pulnionary circulation. — Congestion. Heart disease. Emholism of pulmonary artery. Clot in heart. Heart failure as when fatty or dilated. Anemism or mediastinal tumour pressing on trachea or bronchus. Laryngeal obstruction. — Laryngitis ; paralysis of cord ; growth upon cord ; oedema of larynx. General condition. — ^Ansemia. Fever. Uraemia. Nerve co^/iditions. — Asthma. Hysteria. Paralysis of nervous centres. Graves' Disease. Spasm of respiratory muscles, e.g., from tetanus. (EDEMA OF LUNGS. In the course of pneumonia it may occur in lung tissue adjacent to that inflamed, or in the opposite limg. May attend hronchitis or any lung disease. With pleuritic effusion may attack the other lung. Uraemia ; Fevers ; Passive (cardiac) Congestion from valvular disease, or degeneration of heart's walls. Frequent in conditions of prostration with dorsal decubitus. 136 CLINICAL MEDICINE AND CASE-TAKING. CONTRACTION OF LUNG. Tns'jjection. — Over portion of lung contracted, thorax contracted ; expansion (inspiratory) diminislied. Contraction of one side of chest suggests previous Pleurisy; of an apex, Phthisis. Contraction of left lung may uncover left auricle. Look specially at infra -clavicular regions in adults, and at bases in infants. Palpation. — Note diminislied expansion, general, one-sided, or local. Position of heart ; it may be drawn over by a contracting lung. Pulsation of left auricle may be felt if left lung is contracted. T.Y.F. may be increased. Percussion. — Sound may be of impaired resonance from thicken- ing of pleura with lung consolidation. The resistance felt may be increased. Frequently dulness exists from coincident consolidation. Area of pulmonary resonance above clavicle diminished over a contracted apex. Auscultation. — Respiratory sounds usually weak and may be abnormal from altered conditions of the lung. Look for signs of Consolidation. Phthisis. DISEASES OF THE EESPIKATOEY SYSTEM. 137 SOLIDIFICATION OF LUNG. Inspection. — Yery commonly coincident signs of contraction, especially if the consolidation is at the apex, Palpation. — T.V.F.* increased. Diminished expansive move- ment may also be detected. Note area affected, and whether over one or both luners. FercTission. — Dulness or various degrees of impaired resonance may be observed over area of solidification ; line of dulness not level, and changing with position of patient as in pleuritic efiusion. Note efiect of light and deep percus- sion. Auscultatiov.. — V.R.f increased. Respiration harsh, bronchial, or tubular ; may be cavernous if there be excavation. Puerile in neighbourhood of consolidation. Look for signs of Contraction of Lung ; Phthisis ; Pneumonia. * T.V.F. = Tactile vocal fremitus, t V.E.= Vocal resonance. 138 CLINICAL MEDICINE AND CASE-TAKING. Diagnosis of PNEUMONIA from PLETJRITIC EFFUSION. Inspection. — Expansion di- minished. Ko contraction of chest unless lung shrinks from chronic changes. Palpation. — T.V.F. increased (sometimes diminished), occasionally a pleuritic fremitus felt. Mcnsuratiwu — Karely any bulging. Av^sciUiation. — First stage, fine inspiratory crepitant rales, often also pleuritic rub. Second stage, tubular respiration. Rhonchus or scattered rales. V.R. in- creased. Resolution: Redux loose crepitus, inspiratory and expiratory. Friction sound may return. Percussion. — Dulness at base, usually follo'R'ing the line of lower lobe downwards and forwards. Increased resist- ance felt. No change with alteration of position. Determination of the posi- tion of heart and liver. Is o displacement. Bulging of side of chest affected, also of the intercostal spaces. As fluid is absorbed, contraction and bending of spine to side affected. T.V.F. absent below line of dulness ; may be increased above. Fremitus in first stage. Bulging usual. Tracing by cyrtometer. First stage, pleuritic fric- tion, inspiratory, expiratory, or both. Second stage, efiu- sion. Respiratory murmur absent in axilla, frequently blo-^ing respiration near spine ; puerile at apex. V.R. absent or ffigophonic. Resolution : Return of respiratory sounds at base. Redux friction. Line of dulness at base level coming round to the front. Dulness shifting with position of patient. May be tympan- itic above fluid. Heart displaced, especially with efiusion on left side ; liver may be depressed. Hypodermic syringe may be used to draw off the fluid. DISEASES OF THE EESPIEATOEY SYSTEM. 139 PLEUEISY. Friction heard during inspiration, or expiration, or during both, periods ; it is lost after effusion has occurred, and may return after absorption of fluid or reduction of a » pneumonia. Friction fremitus often felt. Friction of pleural surface usually attended with pain, causing patient to hold his breath ; he lies on side affected. If the pleurisy be secondary to lung disease, e.g., phthisis, symptoms will be those of the lung disease. Pyrexia in pleurisy, lower than the inflammatory fever of pneumonia. See signs of Pleuritic Effusion, P. = ; T. = ; R.= . Causation, see same in Pneumonia. Pleuritic effusion is always albuminous ; occasionally it coagu- lates from presence of fibrin. EMPYEMA. Often not distinguishable from serous effusions before tapping. It is most common in young subjects, debilitated or very strumous. Also when effusion is very chronic. Tempera- ture not necessarily high. More displacement of chest walls and viscera than with serous effusion. Temperature often elevated, but not necessarily so. It may point under the skin in front of chest, laterally, or behind. May occur in Septicsemia, Pyaemia, Erysipelas, Scarlet Fever, Puerperal Fever. It may discharge by bronchus. HYDROTHORAX. Passive dropsical effusion without pleurisy. May occur from Passive (cardiac) Congestion, Bright's Disease, etc. It is usually double and unaccompanied by fever. 140 CLINICAL MEDICINE AND CASE-TAKING. PHTHISIS. Physical signs. — Signs of Consolidation and Contraction of Apex of lung. Carefully ins])ect movement in infra- clavicular fossa on each side, examining for signs of contraction of tlie apex. Palpate, noting if T.V.F. is increased. In some cases the left auricle is uncovered from contraction of the left lung. Percussion gives a dull or wooden note ; note the sound of light or deep per- cussion. The resistance increased over consolidated lung. It may be amphoric over a vomica, but still the resistance is augmented. Auscultation shows V.R. increased, respira- tion harsh or bronchial, with adventitious sounds, scattered rales, crepitation. Digestion. — Dyspepsia often troublesome. Diarrhoea may be due to tubercular Ulceration of Intestines. Circulation. — Note force and strength of heart's action ; it often partakes in the general wasting. Nervous system. — General condition. Sleep. Urine. — Albuminuria may be present. Diabetes is a frequent cause of phthisis. DISEASES OF THE EESPIEATOET SYSTEM. 141 PHTHISIS. Cough, vritli expectoration and Haemoptysis, debility and weakness, emaciation. Sweatings especially at night. Flushings ; fever ; dyspnoea on exertion. Angemia, and in women amenorrhoea. Muscular irritability often marked. In pregnant women phthisis is often temporarily arrested, becoming active after parturition. In advanced cases there may be cedema of the legs. Causation. — Inheritance ; history of consumption or Scrofulous disease in family ; give ages of any members of the family who died. Hygienic conditions, locality of residence with regard to climate and dampness, dusty trades. Exposure to cold. Sequent to acute lung diseases, or haemoptysis. A common termination in diabetes mellitus. Possibly it is communicated from the diseased to persons predisposed. Complications. — Laryngitis, bronchitis, pneumonia, heemop tysis. Pleurisy, empyema, pneumo-thorax. Failure of heart's action ; thrombosis ; bed-sores. Diarrhoea or Melsena from tubercular ulceration of intestines ; fistula ; Peritonitis ; Liver large, fatty or amyloid ; Albuminuria ; General Miliary Tuberculosis ; CEdema of legs. Signs of a cavity (vomica). Percussion, giving a metallic cracked-pot sound on auscultation ; respiration blowing, tubular, cavernous, with moist rales at apex. Pectoriloquy. 142 CLINICAL MEDICINE AND CASE-TAKING, PNEUMONIA. Physical signs. — Signs of Consolidation over hepatized lung. Earliest sign, fine inspiratory crepitation resembling the rustling of hair ; there may be also a pleuritic friction. In hepatization, dulness along outline of the lobe solidified ; if at base, sloping downwards and forwards. T.V.F. usually increased. Respiration tubular and often accom- panied by rhonchus and rales. Voice broncho-phonic. On resolution respiration becomes less tubular ; crepitation, loose inspiratory and expiratory ( = redux crepitation). A return of the friction rub may be heard. V^ Digestiwi. — Tongue furred ; thirst ; anorexia. There may be I vomiting, diarrhoea, Jaundice. Circulation. — Note force of impulse and first sound of heart. Characters of pulse. Nervous system. — General condition of Nervous System; sleep, restlessness. Delirium. Urine. — Scanty, with excess of lithates ; chlorides deficient. May be albuminous. Complications. — Pulmonary oedema ; collateral congestion. Bronchitis ; high fever ; failure of heart, pulse becoming weak and soft. Jaundice ; Delirium ; Albuminuria ; Typhoid State, DISEASES OF THE RESPIRATORY SYSTEM. liS PNEUMONIA. In acute cases onset sudden with rigor, fever, quick breathing. Pleuritic pain and dyspnoea usually subside -^ith the pyrexia, and coincidently with the signs of hepatization. Cough ; expectoration viscid, golden colour, occasionally streaked with blood ; it may be accompanied by aerated, frothy bronchial sputum. N"ote date of disease ; P. = ; T. = ; R. = . Pleuritic pain may return during resolu- tion. Symptoms usually subside by crisis ; dyspncea, fever, disti-ess passing off suddenly, leaving lung hepatized and patient prostrated. Classes ofPneuvionia. — Acute sthenic as above described : usually at base. Asthenic "odth adynamic symptoms : less sudden onset and no marked crisis ; less distinctly marked signs of solidification ; much tendency to bronchitis and pulmonary cedema, patient tending to the Typhoid State. , It may end in Gangrene of Lung-. Pneumonia of the apex. Frequently accompanied by grave nervous disturbance, and long convalescence or subse quent phthisis. Causati&iu — Exposure to cold. A complication of fevers. Secondary to chronic disease, e.g., of lungs or kidneys; rheumatism ; injur}'- ; adjacent inflammation or disease, e.g., pneumonia, cancer, tubercle. \ 144 CLINICAL MEDICINE AND CASE-TAKING. EMPHYSEMA. Physical sigris. — Chest may be large or small ; expansion is markedly diminished, and such movement as there may be is usually vertical without forward expansion. Heart's impulse more or less encroached upon, and marked by lung covering it, but it may be felt as somewhat diffused. General hyper-resonance on percussion. Absolute dulness over heart may be wanting with an extended area of relative dulness. On auscultation, expiratory sound much prolonged ; feeble and toneless, harsh, often accompanied by rhonchi and sibili. Liver may be depressed. Circulation, — Pulse feeble ; right ventricle dilated ; heart may be hypertrophied. Passive Venous Congestion. Urine. — May be scanty and albuminous. Chronic Granular Kidney not uncommonly accompanies emphysema. Causation. — Vicarious dilatation, e.g., adjacent to pulmonary collapse or consolidation, or cells obstructed by bronchitis, Paroxysmal cough ; laborious work ; Hooping Cough ; heart disease ; Alcohol ; Gout leading to ill-nourished condition of lungs. Senile changes. DISEASES OF THE RESPIRATORY SYSTEM. 145 EMPHYSEMA. Lungs lose their elasticity, much aerating smface is lost, and many pulmonary capillaries destroyed, thus obstructing the flow from the right ventricle. Passive venous congestion results. The difficulty of expanding lungs with diminished elasticity throws respu'atory muscles into strong action, and the sterno-mastoids are often hypertrophied. The patient may emaciate or grow fat ; in neither case is nutri- tion good. Usually chronic winter cough and liability to acute bronchitis. Complications and accompaniments. — Heart : right Ventricle Dilated and hypertrophied ; veins large ; cyanosis ; Tri- cuspid Eegnrgitation. (Edema of feet. Bronchitis due to passive congestion of bronchial veins, which empty their blood into the right heart. Dyspnoea on exertion. Albuminuria may be from coexisting Bright's disease, and is then usually constant ; if albumen be due to renal conges- tion it may pass off with other signs of congestion, the albumen lessening and the quantity of urine increasing. Cutaneous capillaries of cheeks often enlarge. 146 CLINICAL MEDICINE AND CASE-TAKING. BRONCHITIS. Physical signs. — If bronchitis is secondary to, or complicates other disease of lungs, the signs will be partly those of that other diseased condition. Aiiscultaiion. — Often gives negative results, especially iu chronic winter bronchitis. E-honchi ; sibili ; rales. Palpation. — Rhonchi are sometimes felt by the hand especially in the elastic chests of infants. Palpate heart. Percussion. — Xo change from the normal, or temporary tonelessness in parts. Inspectimi. — Observe chest movements ; collapse of chest at apices, or in hj'pochondriac regions. Dyspnoea. Urine may be albuminous, a similar cause producing Bright's disease and bronchitis. See Albuminuria. Inquire for—?. = ; T. = ; R. = ; W. = . Signs of Consolidation of Lungs ; signs of contraction. Cough ; Expectoration ; Haemoptysis. ASTHMA. Respiration. — Percussion unaltered during paroxysms ; shrill whistling sibili. Examine lungs during paroxysms and during intervals. The paroxysms, note their frequency and duration, exciting and predisposing causes. Cough ; expectoration. Causation. — Hereditary tendency to neurosis. Reflex causes, uterine, constipation. Tubercular diathesis ; Emphysema ; Heart Disease; Uraemia. May occur in Bright's disease without other signs of anaemia. DISEASES OF THE RESPIRATORY SYSTEM. 147 BRONCHITIS. This condition may be acute or cki'onic ; primary or secondary to other disease, e.g., Emphysema, Phthisis, Pneumonia, etc. It is characterized by cough, "with expectoration usually frothy and watery, sometimes viscid or purulent ; dyspncea. Fever usually slight, but high in children. Post-sternal pain and tenderness, increased on coughing ; skin over sternum sometimes sore. Causation. — Exposure to cold ; fevers ; bronchitis secondary to chronic lung conditions ; phthisis ; emphysema secondary to acute conditions ; pneumonia ; pleurisy. Secondary to heart disease ; Eickets ; mechanical irritants. Course of disease if towards fatal termination. — Inability to expectorate. Rapid respiration. Pulse becoming weak, compressible, irregular ; heart distended on the right side ; veins prominent ; cyanosis. (Edema of legs increasing. Rales all over lungs. Sleeplessness. Tendency to Coma and the Typhoid State. Urine scanty and albuminous. Temperature falling. In children collapse of chest at bases with infalling of epi- gastrium. ASTHMA. An affection characterized by paroxysms of dyspnoea. Paroxysms. — Orthopnoea ; respiratory muscles, ordinary and extraordinary, at work. Chest fully dilated and respi- ratory movement almost nil. Sense of want of air. Yoice weak or lost. Onset of paroxysm sudden, subsidence rapid ; they frequently occur at night. They may be preceded by drowsiness and a sense of fatigue. 14S CLINICAL MEDICINE AND CASE-TAKING. LARYNX, DISEASE OF. Acute conditions. — Diphtheria, croup, catarrh, oedema, lar}m- gismus stridulus. V Chronic conditions. — Laryngitis : syphilitic, strumous, or phthi- ■ sical. Hysteria. Palsy of vocal cords, or one cord. General condition. — P. = ; T. = ; R. = ; W. = . State of nutrition ; signs of struma or Syphilis ; Rickets ; Phthisis. Digestion. — Examine mouth and fauces, using laryngeal re- flector. Circulation. — Examine heart as to strength and dilatation of right side ; venous fulness ; strength and regularity of pulse. Seek for signs of Aneurism. Respiration. — Signs of laryngeal disease ; laryngoscopic appear- ances ; movements of cords. Bronchitis, oedema of lungs, pneumonia, etc. Chest movements. Look for Phthisis. Xervous system. — Signs of Convulsions, thumb turned in fist ; chronic spasm of muscles ; hysteria. Palsy of one cord, usually from pressure on recurrent nerve. See Aneurism. Urine often albuminous in diphtheria ; there may be coincident acute Bright's disease. DISEASES OF THE PwESPIKATOEY SYSTEM. 149 LARYNX, DISEASE OF. Signs of Laryngeal disease. — Voice husky or lost ; stridulous inspiration, aphonia, cough, dyspncea, cyanosis. Dila- tation of right side of heart, and other signs of obstruction to the entrance of air, e.g., infallingof supra-sternal notch, supra-clavicular spaces, and epigastrium, and in young children collapse of the hypochondriac regions. Tracheo- tomy may be required when this obstruction is extreme ; in such a case observe the condition of the heart, pulse, and circulation before and after operation. Laryngismus Stridulus. — Mostly in children ; spasmodic crow ing sound on inspiration, child being well in intervals. Frequent during dentition, in Rickets, and associated with general Convulsions. (Edema may occur during Bright's Disease, Erysipelas, etc., acute catarrh from cold, or with onset of Measles. In Hysterical Aphonia cords are seen healthy but motionless : pharynx often very anaesthetic. Functional Aphonia. 150 CLINICAL MEDICINE AND CASE-TAKING. DISEASES OE THE DIGESTIVE SYSTEM. SIGNS OF DIGESTIVE FUNCTIONS. Ajwetite. — Good, bad, indifferent, altogether lost. Frequency of recurrence, capricious and fanciful; variable, excessive, voracious. Nausea. Vomiting". Fulness or pain after food. Enquire how soon after food ; its character and duration ; whether pain is relieved by- vomiting. "Whether pain without food. Flatulence and eructations. Eructations. Heartburn. "Water-brash. Pyrosis, State of Bovjels. — Regular, constipated, relaxed, with or with- out pain. Diarrhoea ; frequency of action. If disturbed see and describe the motions — solid, liquid, light, clay- coloured, dark, black ; hard scybala, flattened or tape-like, well formed, with blood, pus, etc. INTESTINAL WORMS. T(xnia mediocanellata — beef tapeworm. — The head is at the narrow portion of the worm ; it has four sucking discs, but is unarmed. Taenia solium. — Less common in England. Pork tapeworm ; four suckers and an armed head. T. Bothriocephalus latus. They live in small and large intestines. Thread worms — Oxyuridis — live chiefly in rectum ; common in children. Lumhricus, round worm. Ascaris lumbricoidis lives in upper intestine, and may be vomited. DISEASES OF THE DIGESTIVE SYSTEM. 151 SIGNS OF DIGESTIVE FUNCTIONS. Appetite increases with thirst in Diabetes. Anorexia (loss of appetite) and thirst in Fever. In children often variable, especially in nervous cases ; they often drink much in health, when urine is scanty with high sp. gr. Appetite is often lost in functional disturbance of the nervous system, e.g., over- work, loss of sleep. In Hysteria and insanity the appetite may be greatly perverted ; so also during pregnancy. State of Bowels. — Constipation may result from Plumbism, senile atrophy of bowels, inactive habits of life, ill- arranged diet. Relaxation or looseness from Dysentery, Tllceration of Bcwels, or other organic condition. In infants from ill-feeding or summer heat. 152 CLINICAL MEDICINE AND CASE-TAKING. EXAMINATION OF THE MOUTH AND THROAT. On obtaining a good view of all parts of the mouth, see — tongue ; hard and soft palate, with uvula ; pillars of the fauces, anterior and posterior ; tonsils ; pharynx ; the buccal cavity ; cheeks and lips, mucous membrane ; gums ; teeth. Tongue. — Mucous membrane and condition of muscle. In- dented at edges by the teeth ; flabby ; clean or coated with far ; white, yellow, dirty, dry, or moist. Enlarged papillae at tip projecting through far. How protruded ; straight or deviating to one side, kept well out and steady, or a jerked, tremulous, distinct muscular tremor. Palate and Uvula. — High arched roof, cleft. Ulceration, destruction of soft palate, adhesions. Movements of soft palate and fauces. # Tonsils. — Enlarged, one or both. Smooth, pale or congested ; "with large follicles. Ulcers superficial or deep, if sym- metrical. Exudation on surface. Pharynx. — Mucous membrane and movements. Look for ulcers or old sears and adhesions. Thrush in children ; exuda- tion in diphtheria. Teeth.. — Look for tender teeth ; those subjects of caries ; see if wisdom teeth be cut. Note condition as to dentition in infants. Gums. — Whether of normal substance or shrunken ; condition of mucous membrane. DISEASES OF THE DIGESTIVE SYSTEM. 153 EXAMINATION OF THE MOUTH AND THROAT. It is necessary to obtain a good light in the pharynx ; hence it is often convenient to use a lamp and the frontal reflector of laryngoscope. There may be signs of local or general disturbance. Tongue. — Flabby and coated in dyspepsia ; often red with Gastric Ulcers and Cerebral Vomiting. Protruded to one side in Hemiplegia. Tremulous in Alcoholism, excessive smoking, General Paralysis of the Insane. Jerked and twitching in Chorea. Ulceration from local irritation. Ulcer of frsenum in hooping cough. Syphilis. Epi- thelioma. Palate and Uvula. — Palate high, arched, flat, cleft. Ulcer- ation, scars, adhesion from scrofulous disease or Syphilis. Uvula commonly elongated. Movements of palate and uvula affected in palsy of Nerve YII. Tonsils. — Chronic enlargement in rickets, often with deafness. Ulcers symmetrical in secondary syphilis. See Quinsy, Diphtheria, Syphilis. Pharynx. — Scars from syphilis or strumous ulceration. Paralysis from diphtheria. Epithelioma. Post-pharyngeal abscess from spinal caries. Teeth. — Upper central incisors (of second dentition) may be dwarfed, with atrophy of the middle lobe in Inherited Syphilis. Much ground in gouty people and children who suffer from Headaches. Gums. — Blue line in Plnmbism. Spongy in mercurialism. Swollen and bleeding in scurvy. Covered with sordes in fever. 15i CLINICAL MEDICINE AND CASE-TAKING. DIARRHCEA. K'ote mode of onset and duration ; if attended with pain, griping ; Melaena ; tenesmus (frequent desire to evacuate the bowels, but without effect). Whether acute with paroxysmal griping, melaena, collapse, as in cholera. Motions passed. — Relaxed, liquid, pea-soup-like ; containing bile or not ; scybala, shreds of mucous membrane, undigested food, worms. VOMITING. Note the frequency of vomiting ; whether it occurs only after food ; whether giving relief to symptoms ; if affected by position. State of tongue and bowels. Examine abdomen for tenderness ; signs of disease of stomach. See general condition of Nervous System. Signs of Brain Disease. Examine urine. Matters vomited. — Food unchanged; bile-stained fluid; clear acid fluid ; yeast-like matter containing sarcinae seen on microscopical examination ; blood (hsematemesis) ; dark coffee-grounds-like matter, altered blood ; lumbrici. Faecal matters may be thrown up in obstruction of bowels low down. DISEASES OF THE DIGESTIVE SYSTEM. 155 DIARRHCEA. May be indicative of local disease or general disturbance. Causation. — Disease of tbe bowels; Tubercular TJlceration ; Amyloid Disease ; stricture of bowel, rectum ; scybala ; enteric fever ; Dysentery ; cbolera ; erysipelas, etc. ; Bright' s Disease; ill-feeding; Alcoliolisni ; exposure to heat and cold ; poisoning ; Rickets ; nervous disturbance ; Graves' Disease. Previous constipation. VOMITING. May indicate local or general disturbance or brain disease. See Cerebral Vomiting. Causation. — Stortiach. — Gastritis ; dilatation of stomach. ; catarrh secondary to Cirrhosis of the Liver ; irritating food ; Alcoholism; poisons; Cancer; Gastric Ulcer ; constriction of pylorus or duodenum. Eeflex causes. — Pregnancy; ovarian disease; uterine disturbance ; dysmenorrhcea ; dentition ; intestinal worms ; Gall-stones ; Eenal Calculus ; Addison's Disease ; liver disease, cancer, abscess, etc.; disturbance of special senses, glaucoma, ear disease. Attendant on paroxysms of hoop- ing cough. Brain disease. — Headache; Hysteria. See Cerebral Vomiting. Blood conditions.— Ferer ; malaria ; Bright' s Disease ; Obstruction of Bowels; Peritonitis. 156 CLINICAL MEDICINE AND CASE-TAKING. ACUTE ABDOMINAL PAIN. Enquire as to digestive functions ; previous attacks of Biliary Colic, Eenal Colic, gastric ulcer. Examine mouth and tongue for indications of Gastric Ulcer, poisoning ; and gums for Line lead line. Palpate and examine abdomen ; note if tender and tympanitic ; position of the patient, whether still and prostrate or moving about. In females look for signs of pregnancy, uterine action, or haemorrhage. Examine heart, pulse, skin, pupils, urine. T. = . Note if much collapsed ; whether able to speak ; whether vomitincr. DYSPHAGIA. General Condition. — Anaemia. Signs of Cancer. General con- dition of Nervous System. Syphilis. Senile degeneration. Digestion. — Examine mouth and throat for ulceration, scars, etc. Auscultate spine while patient drinks, looking for gurgling at one point. Pass oesophageal bougie. Vascular system. — Signs of disease of vessels or aneurism. H^MATEMESIS. Enquire as to the general signs of the Digestive Functions, previous vomiting, pain, tenderness, etc. See causes of Vomiting. Examine the matters vomited and the motions as to htemon-hage, etc. Examine the abdomen generally. Look for disease of stomach and liver. Examine lungs and heart to detennine absence of causes of hemoptysis. See diagnosis of Haemoptysis from Haematemesis. Urine. Anaemia. Amenorrhcea. DISEASES OF THE DIGESTIVE SYSTEM. 157 ACUTE ABDOMINAL PAIN. Causation. — Rupture of hollow viscera, stemach, intestine, bladder. Renal or Biliary Calculus. Irritant poison. Over-feeding. Colic, simple or from gout. Plumbism, often relieved by pressure. Rupture of abdominal Aneurism, abscess, Hydatid. Peritonitis. Perihepatitis. Ulceration of bowels with peritonitis or perforation. Tubercular Ulceration. Acute disease, e.g., cholera. In females during pregnancy, concealed accidental haemorrhage. Pain and tenderness suggest enteritis or peritonitis, rather than colic, the latter being often relieved by pressure. DYSPHAGIA. Causation. — Tonsillitis ; syphilitic ulcerations ; disease of larynx ; cancer of oesophagus or of cardiac end of the stomach ; thoracic tumour ; abscess, post-pharyngeal or mediastinal ; Aneurism ; traumatic injury or action of caustics ; ulcer of stomach at cardiac end ; Diphtheritic Paralysis ; Bulbar Paralysis. lu General Paralysis of the Insane there is much tendency to choking. Hysterical dysphagia. HiEMATEMESIS. Causation. — Gastric Ulcer. Corrosive poisons. Cancer of Stomach. Continued vomiting (reflex). Acute gastric catarrh. lardaceous Disease. Pyloric ulcer. Bright' s Disease ; uraemia. Passive Congestion of stomach. Scurvy. Cirrhosis of Liver. Vicarious menstruation. Blood swallowed and vomited. Patient often faints from haemorrhage, previous to the discharge of the blood from the mouth. 158 CLINICAL MEDICIXE AND CASE-TAKING. MELiENA. General condition. — State of nutrition. Anaemia or cacliexia. Digestion. — Examine motions ; presence of abdominal pain or signs of gastric disease, pain on defaecation, etc. Enquire for signs of Cancer ; history of malaria ; previous diarrhcea ; signs of stricture of bowels. Examine abdomen ; if necessary examine rectum ; urine ; lungs, as to signs of tubercular disease. OBSTRUCTION OF THE BOWELS. General condition. — Position of patient ; pain ; abdominal tenderness ; signs of collapse. T. = . Note wlien bowels last acted. Digestion. — Habitual condition of bowels, regular, costive, or relaxed. Previous signs of disease, e.g., Melaena, Vomiting. State of tongue. See and describe the motions passed. Examine abdomen, especially the abdominal rings, and femoral rings for hernia. Note fulness, tenderness, local swelling or tumour ; an elongated tumour from Intussuscep- tion. Signs of Peritonitis. Track out colon, if distended, by palpation and percussion. Note if any signs of con- traction at any point. Examine rectum with the finger, or give enema noting what quantity of fluid can be retained ; pass the long tube. Sometimes the whole hand is introduced into the rectum. Examine per vagiaajn. — Signs of pregnancy. See general sicrns of Cancer. DISEASES OF THE DIGESTIVE SYSTEM. 159 MELJENA. May be caused by all tbe causes of Hsematemesis, the blood passing from the stomacli to tbe intestines. Cirrhosis of Liver, or other obsti'uction to portal circulation. TJlceration of Bowels, tubercular. Gastric Ulcer. Cancer of bowels. Enteric Fever. Dysentery. Intussusception. Pelvic hsematocele or abscess. Piles may cause bleeding from the anus. Villous growth in rectum. Bright's Disease. OBSTRUCTION OF THE BOWELS. Causation. — I. Compression. — Cancer or inflammatory mass involving intestine ; Abdominal Tumour ; pregnant uterus ; ovarian tumour ; pelvic tumour ; uterine, ovarian, cellu- litis ; retroverted uterus. II. Changes in wall of gut. — Cicatrization of intestinal ulcers, dysenteric, tubercular ; congenital deformity of rectum, etc. ; Cancer ; epithelioma and syphilitic disease of rectum. III. Strangulation. — Generally in small intestine, hernia ; constriction from mesentery of portion of intes- tine drawn into a hernial sac ; or from bowels, due to peritonitis. IV. Plugging. — Undigested substances, fruit stones and seeds, hardened fgeces, masses of worms. Intussusception ; volvulus. Symptoms vary according to the position of the obstruction, its degree, its cause, the complications. If in small intestines there may be no marked and characteristic symptoms. The motions may be pipedike or not formed. Formed motions may be produced by faeces passing the stricture and being moulded in rectum. Constipation ; flatulence. If in rectum, pain and straining on defsecation. 160 CLINICAL MEDICINE AND CASE-TAKING. GASTRIC ULCER. Digestimi. — Pain immediately after food, relieved only by vomiting. Water-brasli vomiting. HEematemesis. Melaena. Inability to take solid food. Localized tenderness at epigastrium ; no tumour felt. Bowels usually confined ; examine the motions. Tongue usually red. JVote. — General condition ; position of patient ; state of nutri- tion ; signs of Ansemia. General condition of abdomen. Signs of Hysteria. General condition of the Nervous System. W. = . Urine. TYPHLITIS. Local examination of right iliac fossa. Vaginal or rectal examination to determine absence of pelvic cellulitis. Causatimi. — Hardened fseces ; undigested food ; dysentery. Local concretion in appendix. Cherry stone, or fish bone, etc. DISEASES OF THE DIGESTIVE SYSTEM. 161 GASTEIC TJLCER. Pain may be less if the ulcer is on the lesser curvature of stomach. In long-lasting cases, some thickening of walls of stomach may be felt, or stricture of the pylorus may result. Usually there is emaciation, antemia, or cachectic appearance. Menstruation absent or disturbed. Recovery may occur for a while with tendency to relapse of the symptoms, or perforation and Peritonitis, vomiting, haemorrhage, exhaustion. Causation. — Most common in females ; specially accompanies disordered menstruation ; may result from action of caustics. Complications. — Fistulous communication -udth external surface or with other parts of intestines. Pyaemia. TYPHLITIS. Abdominal pain ; local signs of inflammation in the right iliac fossa, pain, tenderness, swelling. Local peritonitis with infiltration of the cellular tissue ; it may suppurate. Constitutional disturbance with fever may be considerable if the bowel is involved ; less acute if only around the bowel. Perforation of bowel may follow. Usually pain and difficulty in moving right leg. M 162 CLINICAL MEDICINE AND CASE-TAKING. ABDOMINAL CANCER. General condition. — Note state of nutrition, W. = Emaciation. Pain in back, exhaustion, and cachexia, Avith the general signs of Cancer. Digestion. — Signs of digestive functions. Vomiting, haemor- rhage, acid secretions, stomach pain. Examine abdomen. — Clear out bowels A^ith purgatives or enemata ; empty bladder. Palpate and percuss to detect any abdominal tumour. Note any signs of Obstructed Bowels ; Peritonitis ; Ascites. Examine rectum and per vaginam if necessary. Cancer of Stomach, — A mass may be felt in epigastrium, or an increased resistance, often most distinct along greater curve of stomach. A rounded and movable mass may be felt over the pylorus. Cancer of Intestines. — A mass may be felt on palpation ; it may be movable. Clear out bowels. Inspect and describe the motions, whether full-sized or flattened and small. Melaena. If there is obstruction, or arterial haemor- rhage, examine rectum with finger. Look for piles. DISEASES OF THE DIGESTIVE SYSTEM. 163 ABDOMINAL CANCER. May affect stomacli, intestines, peritoneum, mesenteric glands, liver, kidneys, spleen, uterus. Secondary deposits in tlie liver are common. See Abdominal Tumour. Cancer of Stomach. — General signs of cancer. Pain in region of stomacli, a very varying symptom. Vomiting acid frothy matter, often with sarcinee ; there may be arterial Haematemesis or coffee-ground-like matter. Excessive acid secretion. Usually it is primary. Secondary deposits may occur in the liver ; it may creep on to pylorus and involve gall-duct. Jaundice. A mass may thicken the pylorus causing a tumour that can be felt there, and stricture with vomiting late after food. Scirrhus of stomach may run its course through many years. With a mass that can be felt, patient may still gain weight. Cancer of Intestines. — Usually primary ; most common in the sigmoid flexure, csecum, and rectum. Abdominal pain. Tendency to annular contraction, causing Obstruction, May be mistaken for feecal accumulations. Note. — Ulceration of rectum may be from epithelioma oi Syphilis. 164 CLINICAL MEDICINE AND CASE-TAKING. ULCERATION OF BOWELS. Typhoid. Cancer. Epithelioma at anus. Syphilis. Ulceration from gall-stones, scybala, intussusception, etc. Dysentery. — Note state of nutrition ; Anaemia. P. = ; T. = ; R. = ; W. = . Digestion. — Appetite. Abdominal pain or tenderness. Evacua- tions: colour, consistence, smell, bile, mucus, or sloughs. Liver. — Size, absence of tenderness, jaundice, etc. Complications and Sequelce. — Chronic dysentery. Haemorrhage from bowel. Abscess of liver. Tubercular Ulceration. — Getieral condition. — Emaciation ; excessive sweating. Digestion. — Appetite. Abdominal condition ; fulness, tender- ness, pain, general or localized. Bowels relaxed ; may be acting with pain and Melaena. Enquii'e for fistula in ano. Eespiration. — Examine lungs, and look for signs of Phthisis. DISEASES OF THE DIGESTIVE SYSTEM. 165 ULCERATION OF BOWELS. Dysentery. — A disease more common in the tropics than here. Caused by malaria, scorbutus, bad water, salt food, etc. It may occur in an acute or chronic form. It is febrile, characterized by tenesmus with the passage of mucus without fsecal matter or bile , sloughs may be passed with blood. These symptoms depend upon inflammation of the colon with exudation ; it may extend to the small intestine. Tubercular Ulceration. — Common in cases of jjhthisis and other sti'umous affections. Abdominal pain, diarrhoea, and melsena may result. The tubercular ulcers in the bowels are transverse ; they may heal up, leading to scars, which may cause stricture of the bowels. Ulcers occur mostly in the lower part of the ileum and caecum. Complications. — Peritonitis. Ascites. Perforation of bowels Acute Miliary Tuberculosis. 166 CLINICAL MEDICINE AND CASE-TAKING. ABDOMINAL TITMOUIIS. General condition. — State of nutrition. "W. = . Signs of Cancer or Scrofulosis. Abdominal pain, tenderness, vomit- ing, condition of bowels, signs of Obstruction, Digestive functions. Look for Ascites, Peritonitis, Abdominal Cancer, oedema. Urine. Examination of oJbdomen. — Palpate and percuss abdomen ; tliiis endeavour to detect any tumour present. Define its position Tritb regard to tlie anatomical regions ; determine its boundaries and connections ; particularly note if distinct fi'om liver and pehdc organs. Map out liver and spleen, showing them of normal size. Xote physical conditions of tumour, its size, if smooth, rounded, lobu- lated, hard, impressible, doughy, fluctuating. If mov- able or moving "Rdth respiratory movements. Measure the abdomen, girth at base of chest and at the umbilicus, vertical measurements from umbilicus to pelvis, and umbilicus to xiphoid cartilage. In the normal the um- bilicus is about an inch nearer to the pubes than to the sternum. Xote pain or tenderness. Empty bowels and bladder. History. — ^Commencing on one side ; enlarging from below upwards ; enlarging of the abdomen uniformly ; with pain and fever or not. Did symptoms commence at a menstrual period ? Percuss, palpate liver, define and mark on skin the vertical and other dimensions. DISEASES OF THE DIGESTIVE SYSTEM. 167" ABDOMINAL TUMOURS, Ovarian.— 'Globular, movable, fluctuating ; usually situated more to one flank than th.e other. Springing from the pelvis and may be felt there. Usually dulness in centre of abdomen with resonance in the flanks. If very large may be mistaken for ascites. See diagnosis of Ovarian Tumour from Ascites. It may be accompanied by ascites. Dulness over an ovarian tumour shows that no intestines are in front of it ; so also with a pregnant uterus. Kidney. — Colon usually passes in front of tumour however large it becomes ; this may be indicated by partial and varying resonance over it. There may be mixed resonance and dulness, varying on different occasions. Tumour may be felt in the flank, usually between false ribs and ilium ; a tumour in this region may be renal, peri-nephritic, fsecal in colon. Abscess ; cancer ; hydro-nephrosis ; blood-tumour. The outline is rounded or lobulated (cystic tumour), not easily defined. Absence of fluctuation. liver. — See Large Livers. A hepatic tumour descends on in- spiration. Gall-bladder ; Hydatid;. Cancer. Abdominal Pulsation common in hysterical women and dyspeptic subjects. Throbbing of abdominal aorta also common in emaciatioiL. 168 CLINICAL MEDICINE AND CASE-TAKING. FLUID IN peritoneum:. Physical signs. — Enlargement of abdomen. In dorsal position, dulness on percussion over tlie fltiid, which gravitates into the flants leaving central region clear ; on the dependent side of abdomen, a distended colon may give a tympanitic note, but on palpation in this flank the weight of the fluid is felt, line of dulness shifting with position. Thrill transmitted on filliping abdomen ; fluctuation. When placed on hands and knees, fluid will gra^atate to the umbilicus. Clear out bowels j §mpty bladder ; examine per vaginam. Symptoms. — Dyspnoea and thoracic breathing. Pressure on renal veins may cause scanty urine and Albuminuria, Pressure on iliac veins causing oedema of legs. Superficial abdominal veius enlarged. Causation, — Cirrhosis of Liver, Cardiac disease. Disease of peritoneum, tubercle, cancer, Peritonitis. Exposure to cold. Ovarian or other abdominal tumour, CVjiditions simulating Ascites. — Ovarian cyst. Hydatid cystic kidney. Pregnant uterus. Distended urinaiy bladder, Eluid in intestines. See Abdominal Tumours, DISEASES OF THE DIGESTIVE SYSTEM. 169 ABDOMIKAI TUMOUES, spleen. — Feel for the notcli toi;v'ards anterior margin. Usually firm, flat superficial under abdominal walls without intes- tine in front. Stretching from left hypochondrium. Sur- face may be lobulated ; it may be tender and movable. Pancreas. — Has been stated to be frequently the seat of cancer. Examine fseces for fat ; shake up with ether. Causation. — Hypertrophy ; chronic congestion from cardiac or liver disease ; Ague ; Amyloid Disease ; cancer. Examine blood for leucocythaemia. In children Rickets. Syphilis. Large sometimes in fevers, specially enteric. Frequent seat of Embolism. Abdominal Aneurism.— A tumour pulsating and laterally expansile, with a thrill and systolic bruit often also heard over spine. Pain. No necessary dyspeptic symptoms. Pressure signs less common than in thorax ; it may press on vena cava, or cause erosion of Vertebrae, producing great pain. It does not fall forward Avhen patient is in knee-elbow position. A tumour lying on the aorta may receive a com- municated impulse. The pulsating aorta without disease may often be felt in nervous or dyspeptic patients, especially in females if emaciated. See Aneurism, 170 CLINICAL MEDICIKE AND CASE-TAKING. Diagnosis of OVARIAN TUM0T7R from ASCITES. Palpation. — Definite margins may be felt. Usually situate more in one side of abdomen than in the other. It may be traceable into the pelvis and felt there. Percussion. — Dulness in cen- tral regiqn, intestines giving a resonant note in the lumbar regions. But little shifting of dulness on alteration of position of patient. Menmiration. — Distance of um- bilicus from sternum, equal to or less than that from the pelvis. Greatest girth below the umbilicus- Piispection. — Gen eralroundness of abdomen ; tumour may be seen somewhat rounded and prominent. Fluctuation may be de- tected ; thrill transmitted in any direction on filliping the surface. Dulness in flanks ; cen- tral region tympanitic as patient lies on her back, and shifting with alteration of position. Distance between umbilicus and sternum maintains nor- mal ratio. Greatest girth at umbilicus or above it. Abdomen flattened, but prominent and broad. DISEASES OF THE DIGESTIVE SYSTEM. 171 ABDOMINAL TUMOURS. Tumours ai-ising from the j^^^'vis. — Examine per vaginam. Ovarian. Perimetritis. Pregnant uterus. Inflamiiiatory swellings. — Renal or perinephritic abscess. Pelvic cellulitis. Parametritis ; towards groins and iliac fossse. Fmcal accumulations. — Usually in colon, in either iliac fossa. There may be coincident diarrhoea. Tubercular mesenteric glands. — Masses may be felt. Belly large /and tender, emaciation, diarrhoea. Signs of Scrofulosis. Usually coincident signs of Tubercular Peritonitis. Tympanites. Ascites. Abdominal Cancer may cause enlarged glands. Phantom Tumour. — Arises from local contraction of rectus muscle, one or both. It may be dull on percussion, and visibly prominent ; usually it occurs in the lower portion of the abdomen. It subsides under chloroform. Not uncommon in Hysteria. Intussusception. — Cylindrical tumour produced by intus- suscepted bow^el, movable from day to day. Tenesmus ; passage of blood and mucus. Signs of Obstruction of Bowels. 172 CLINICAL MEDICINE AND CASE-TAKING. PERITONITIS. General condition of po-tient.— Volition, complaints of pain, state of skin, tongue, pulse. Look for emaciation or other signs of chronic disease. T. = ; R. = ; P. = ; W. = . See Ascites ; Abdominal Tumour ; Abdominal Cancer ; Acute Abdominal Pain ; Hysteria. Examine abdomen. Causation. — Traumatic. Rupture of bladder or other \ascera. Ulceration from a gall-stone, etc., action of poisons, pressure on gut from hernia, etc. Exposure to eokl. -pyaemia. Puerperal fever. Bright's Disease. Enteric fever. Enteritis. Cancer. Tubercular Ulceration of Bowels. Pelvic inflammations. Perityphlitis. Abdominal Tumour. Diagnosis. — From gastritis, enteritis, metritis, cystitis, and distension of bladder ; colic ; abdominal hysteria. DISEASES OF THE DIGESTIVE SYSTEM. 173 PERITONITIS. Acute and chronic. Acute cases cliaracterized by abdominal pain and tenderness, with fever, nausea, vomiting, con- stipation, abdominal distension, cold sweats. Patient usually lies on his back with the legs drawn up on the abdomen; collapse, pulse small and wiry, skin moist, extremities cold. Abdomen distended and tympanitic. There may be effusion of fluid. Bowels constipated. Respiration shallow and thoracic. Tubercular peritonitis usually occurs in young scrofulous subjects. • Masses of glands may be felt in abdomen. 174 CLINICAL MEDICINE AND CASE-TAKING. DISEASES OF THE LIVER. JAUNDICE.* A. — Mechanical Obstruction of Bile Duct. I. Obstruction by foreign bodies within tlie duct. II. Obstruction by stricture or obliteration of the duct. III. Obstruction by Abdominal Tumours closing the orifice of the duct, or gi'owing into its interior. B. — Jaundice Indepeiident of Mechanical Ohstrioction of the Bile Duct. I. Poisons in the blood interfering with chemical changes in bile. II. Mineral poisons. III. Liver diseases. IV. Nervous causes. Y. Intestinal accumulation. Jaundice. — Shade and depth of colour. It affects also urine, sebaceous matter and sweat, milk. Taste bitter. Heart's action slow. Cerebral depression common in cases depend- ent upon obstruction, and when there is no obstruction tendency to stupor, coma, typhoid state. Skin liable to urticaria, lichen, boils, vitiligoidea ; itchiness of skin may precede the jaundice. Digestion disturbed, constipation, flatulence, emaciation. In chronic hepatic affections haemorrhages are common. * See Dr. Murchison's table: "Diseases of the Liver." DISEASES OF THE LIVER, 175 JAUNDICE. A. — Mechanical Obstruction of Bile Duct, I. Gall-stones, inspissated bile, foreign bodies from intestines. II. ia) Catarrb of duodenum, extending from gastric catarrh. (&) Congenital defect, (c) Cicatrix after gall-stones, III. Also pressure of glands of transverse fissm-e of liver, amyloid or cancerous. Cancer of Liver. B. — Jaundice Independent of Mechanical Obstrudion of the Bile Duct, I. Relapsing fever, enteric, typhus, pyemia, II. Phosphorus. Metallic poisons. III. Acute yellow atrophy. Congestion of liver in heart disease, lY. Sudden fright. V. Chronic constipation. Jaundice. — Colour pale sulphur, lemon, deep olive. As it passes off skin is the last to clear. Urine may contain jaundiced easts. There may be a bitter taste from bile acids. Diagnosis from — 1, Yellow eye due to subconjunctival fat, 2. Addison's Disease. Here discoloration of skin is patchy and urine is normal, 3. Urine blood-coloured ; may resemble jaundice, but is also albuminous. 4. Infants soon after birth may be red and subsequently yellow, suggesting icterus neonatorum. 5. Cachexia from Anaemia or malignant disease. 176 CLINICAL MEDICINE AND CASE-TAKING. LARGE LIVERS * 1. Lardaceous. Uniform enlargement. See Amyloid Degea- eration. 2. Fatty. Uniform enlargement. 3. Hydatid tumour. Bulging or projecting from liver. 4. Tight lacing may cause do%vnward bulging of liver. 5. Congestion, passive, e.(/., from heart disease. Enlargement uniform. 6. Catarrh of bile ducts. Enlargement uniform. 7. Obstruction of common duct, e.g., sequent to Gall-stones. 8. Pysemic abscess. If numerous, enlargement uniform. 9. Tropical abscess, causing a bulging tumour. 10. Cancer, if secondary, is usually diffused, e.g., secondary to ■ cancer of sigmoid flexure or stomach. Note size of liver, "whether enlargement be uniform or irregular ; whether it be tender ; if accompanied by Jaundice. T.= . Percuss ; palpate and map out the liver. Normal Liver Dulness. — Commencing posteriorly about the tenth or eleventh dorsal vertebra, it ascends slightly towards the axilla and the nipple, then again descends gi'adually towards the median line in front. In median line in front usuall}^ corresponds with the base of the ensiform cartilage, and to the left of this blends with the cardiac dulness at level of fifth space. In right mammary line 4 — 5 inches. Cancer of Liver. — General condition, see Cancer, signs of. Note if jaundiced. Liver large ; its measurements, outline, condition of surface and margin ; if smooth, rough, nodular with masses. Xote pain or tenderness. Spleen rarely enlarged. Look for other signs of Abdominal Cancer. Ascites. ♦ See Dr. Murchison, DISEASES OF THE LITER. 177 LARGE LIVERS. 1. Firm, smooth, easily felt and defined. 2. Less definable ; there may be general fatty growth in the body. 3. A prominent and fluctuating tumour may be felt. 4. Tissue of liver may be healthy, and symptoms may be absent. 5. Active congestion in fevers ; frequent in tropical climates. 6. Accompanied by signs of dyspepsia and jaundice. 7. External pressure on duct may obstruct it. 8. There may be large abscesses, and irregular enlargement. 9. Usually secondary to Dysentery. 10. Primary cancer usually forms a mass that can be felt. Look for — Anaemia. Causes capable of producing Passive Congestion. History of Alcoholism or residence in tropical climates. Malaria. Cancer of Liver. — In primary cases usually cancerous masses, or large nodules, that can be felt. It may be secondary to other abdominal cancer ; then usually diffused in liver, enlarging it uniformly. Such deposits occurring may cause vomiting. Diagnosis from — Nodular contractions of rectus muscles ; Amyloid or Cirrhosis of Liver ; multiple hydatid. N 178 CLINICAL MEDICINE AND CASE-TAKING. SMALL LIVERS. 1. Simple atrophy. 2. Acute yellow atrophy. 3. Chronic ati'ophy. 1. Simple atl'ophy occurs in senile degeneration and inanition. 2. Acute Yellow Atrophy. — General condition much disturbed. History. — Habits, especially as to intemperance. Syphilis. Pregnancies. Jjigcstion. — Anorexia ; vomiting ; tongue fuiTed. Liver. — Xote size and subsequent diminution. Jaundice, with bile in feces. j\'ervoas system. — Headache ; loss of muscular power ; muscular twitchings. General distmbance of Nervous System tending to Coma. Urine. — Urea, uric acid, and salts diminished. Presence of leucine and tyrosine, products of metamorphosis inter- mediate between albumen and the less complex nitrogenous (Compound, urea. Cm'sation. — Alcoholism. Syphilis. Malaria. Typhus. Strong emotional distui'bance. Frequent pregnancy. DISEASES OF THE LIVEK. 179 SMALL LIVERS. 1. No disease and no change of structiu'e of the tissue. 2. Acute Yellow Atrophy. — Liver rapidly decreasing in size ; jaundice without obstruction ; symptoms of blood- poisoning. Fremonitory symj)toms. — Digestion disturbed ; general vague pains. Jaundice slight, bile still appearing in fteces. Fully established disease. — Sets in with sudden onset of symptoms due to the blood-poisoning, depending upon the defective formation of urea and uric acid ; this affects the general condition of the patient. Loss of strength. Jaundice increases ; headache, restlessness, delirium, convulsions, vomiting, coma. Typhoid State. Tongue dry and brown. Hgemorrhages in skin and mucous membranes may occur. Liver dulness constantly and rapidly diminishes. Spleen may enlarge. 180 CLINICAL MEDICINE AND CASE-TAKING. CIRRHOSIS OF LIVER. GeneraJ condition. — Anaemia; emaciation; sallownes3 ; epistaxis; Ascites. Digestion. — Dyspepsia ; flatulence ; vomiting ; piles. Spleen. — Often large. Liver. — Usually small, but it may be enlarged in early stage ; edge and surface rough, h.ob-nailed, hard. Jaundice may be present ; then it is slight. Subsequently liver con- tracts. If there be peri-hepatitis, liver is tender. SYPHILITIC DISEASE OF LIVER. Gummata may be felt on palpation. Liver may be tender from peri-hepatitis ; lobulated from irregular contraction, producing a notched margin. See signs of Syphilis. DISEASES OF THE LIVER. 181 CIRRHOSIS OF LIVER. A chronic disease, mostly caused by chronic Alcoholism. Dyspeptic symptoms, subsequently Ascites or Haema- temesis. Often associated Avith Emphysema and Granular Kidneys. Spleen large from obstruction to the return of its venous blood. SYPHILITIC DISEASE OF LIVER. May result from inherited or acquired disease. There may be gummata, a general change throughout the liver, or peri-hepatitis. 182 CLINICAL MEDICINE AND CASE-TAKING. GALL-STONES. Occasionally they may be felt on palpation, or heard on auscultation. There may be pain on jolting or any sudden movement. They are common with cancer of gall-bladder. A stone may cause obstruction of the common duct and Jaundice. There may be recurrent attacks of biliary colic. Ulceration of gall-bladder may result, and extend to neighbouring organs, causing per- . foration of any of the hollow viscera. BILIARY COLIC. Attacks of severe Abdominal Pain, due to passage of a gall- stone from the gall-bladder to the duodenum. The attacks usually set in suddenly after exertion, and ma}' subside suddenly, and be followed by jaundice. Attacks are apt to recur if there be many stones present. DISEASES OF THE LIVER, 183 HYDATID OF LIVER. A chronic tumour causing an irregular outline to the liver ; usually painless, unless it be inflamed. It may be of any size ; is usually rounded, firm, slightly fluctuating. If there be no adhesion it is depressed on deep inspira- tion ; not accompanied by jaundice unless there be some complication. Usually single, but there may be many in the liver. Diagnosis from — Cancer ; gummata or syphilitic liver witli irregular contractions ; abscess of the liver ; distended gall-bladder ; cystic tumour of kidney ; ascites. See Abdominal Tumours. The spleen is not enlarged, as in some other conditions. Course of disease. — The hydatid may suppurate and burst into the abdomen, lungs, pleura, etc. ; it may form adhesions ; it may shrink up. Fluid in cyst. — Often removed by aspiration. It is not albuminous if there has been no inflammation. Sp. gr., about 1005 ; chlorides abundant. Microscopically, small cysts, with secondary cysts inside, may be seen ; "heads," separate booklets. Highly refractive particles. Cholesterin may be found in fluid. 184 CLINICAL MEDICINE AND CASE-TAKING. DISEASES OF THE URINARY SYSTEM. BRIGHT'S DISEASE. General debility. Anaemia. Dyspepsia. (Edema or anasarca. Necessity to urinate frequently. Skin dry ; often unable to perspire. TTraemia. Digestion. — Dyspepsia ; Vomiting ; diarrhoea ; Haematemesis ; melsena. Vascular system. — Hypertrophy of Heart ; bigh. tension of pulse ; arteries tliickened and bard ; capillaries dilated on cbeeks. Liability to baemorrbages, epistaxis, bsemoptysis, etc. Excited action of the heart in ursemia. Nervous system. — Disturbance of the general condition of Nervous System; Vomiting, Headache, Vertigo, etc. Retinitis albuminuiica. See Uraemia, Convulsions. Uriiu. — Albuminuria almost always present in Brigbt's disease. Quantity altered, usually diminished. Sp. gi\ low ; the total of urea excreted diminished. Casts : fatty, hyaline, larger, small, epithelial, granular. Apparent absence of casts not an absolute proof of absence of Brigbt's disease, but evidence in that direction. DISEASES OF THE UEINAEY SYSTEM. 185 BRIGHT' S DISEASE. The name signifies disease of tlie kidneys accompanied by Albuminuria, and dependent upon structural changes. The disease is usually unattended with pain, or any subjective symptoms characteristic of the disease. Pallor of the face is often a marked sign, and in elderly people is often suggestive of albuminuria. Attention must always be given in taking the history, and in observing, to determine if the disease be Acute or Chronic. Vascular system. — May be profoundly altered and disturbed, as indicated on the other page, the blood changes being shown by anaemia, tendency to haemorrhages, secondary inflammations, etc. Causation. — Exanthemata, specially scarlet fever ; febrile conditions, e.g., pneumonia, rheumatic fever, ague, ery- sipelas ; Alcoholism ; exposure to cold ; wet and cold work ; repeated pregnancies ; dyspepsia ; Gout. It is of great importance to determine whether the disease is acute or chronic. ComplicatioTis. — Inflammatory conditions ; Pericarditis ; Pleu- risy ; Pneumonia. Cerebral haemorrhage ; haemorrhages from mucous membranes. Epistaxis. Uraemia. 186 CLINICAL MEDICINE AND CASE-TAKING. UREMIA. General condition. — Anasarca. Ansemia. Skin liarsli and dry. Look for signs of Contracted Kidneys. Nervous system. — Head Pain; drowsiness; Delirium; Coma; temporary blindness ; retinitis albuminurica ; neuro- retinitis ; Typhoid State ; muscular twitchings ; Convul- sions. Vascular system. — Liability to hgemorrhages from mucous membranes, e.g., epistaxis, Haemoptysis; Hypertrophy of Heart, pulse hard. Pulse often strong till death is at hand. Digestive system. — Dyspepsia; Diarrhoea; Vomiting. Respiratory system. — Breath smelling ammoniacal ; paroxysmal dyspncea, resembling asthma. Urine. — Quantity ; albuminous ; sp. gr. low ; deficient in urea and salts ; Heematuria. Casts in deposit. Gausatio7i. — Bright's disease, acute or chronic. Suppression of urine from obstruction of ureters. Obstruction to renal veins or arteries. Destruction of one or both kidneys by abscess, calculi, etc. Cystic kidneys ; surgical kidneys, sequent to stricture and pyelitis. DISEASES OF THE UEINARY SYSTEM. 187 UIliEMIA. Many of these signs may be met with without urfemia. Inflammatory complications, e.g., Pericarditis, Pleurisy. Dropsical complications, Hydrothorax, hydropericar- dium, Ascites. Ursemia is a condition of blood-poisoning; the breath becomes ammoniacal, and the excretion of urea is much diminished. Diarrhoea or vomiting may lead to a favourable termination. The skin seldom acts spontaneously, but its action is favourable. Symptoms may set in gradually or suddenly, with convulsions. Progress may be towards recovery, especially in acute Bright' s disease ; it frequently ends in death. Relapses and the recurrence of symptoms are common. Pulse full, strong, hard ; heart's impulse strong. Urine. — Scanty or suppressed from Bright's disease. Passive Congestion of kidneys, or pressure upon renal vessels, etc. Causation. — Ureters may be obstructed by calculi or pressed upon by pelvic tumour, e.g., ovarian. Venous congestion may result from heart disease, Emphysema, etc. Renal arteries may be obstructed by embolism or pressure on arteries by an Abdominal Tumour. 188 CLINICAL MEDICINE AND CASE-TAKING. ALBUMINURIA. Causation. — Bright' s Disease. Passive Congestion of the kidneys. Simple or latent albuminuria.* Albuminuria from fevers. Calculous disease, due to presence of pus or blood in urine. In females from leucorrhoeal discharge, etc. , or menstruation. Passive {mechanical) congestion. — Heart Disease or Emphysema, etc., may produce over-fulness of vena cava, and con- gestion of the kidneys. Pressure on the renal veins may also prevent return of blood from kidneys, and be due to pressure of a pregnant uterus or Abdominal Tumour. Ascites pressing on renal veins. Urine. — Sp. gr. ; quantity. Albumen, its quantity and variability under circumstances. Deposit, casts, crystals, blood discs, epithelium. Reaction. LooTc for — Signs of Bright's Disease. Heart disease and Diseased Vessels. Emphysema and other lung disease Causes of passive congestion. * Dr. Geo. Johnson : "Brit. Med. Journ." Dec. 13, 1879. .DISEASES OF THE URINARY SYSTEM. 189 ALBUMINURIA. Passive congestion of the kidney s. — Then the amount of albu- men tends to vary with the other signs of passive conges- tion, e.g., ascites, jaundice, oedema of legs, etc. No history of Bright's disease previous to the cause of congestion. Albumen less abundant and casts but scanty if Bright's disease is absent. Urine of high sp. gr., scanty in quantity, a few granular casts. Simple Albuminuria, i.e., not dependent upon Bright's disease. — Urine albuminous without any marked sti'uctural lesion. May be due to exposure to cold ; excess of nitrogenous food. Often accompanied by oxalates. During fevers and febrile conditions, e.g., typhus, enteric, cholera, diphtheria, pneumonia, rheumatic fever. But few casts, if any. 190 CLINICAL MEDICINE AND CASE-TAKING. HJEMATITRIA. Causatio7i. — Disease in renal tissue, pelvis of kidney, ureter, bladder, urethra. Bright's Disease, acute or chronic. Passive congestion of kidneys. See Passive (Cardiac) Con- gestion. Active congestion of kidneys from alcohol, tur- pentine, cantharides. Traumatic injury. Stone. See Renal Calculus. Bladder, Disease of: cystitis, stone, cancer, villous growth, etc. In females during menstrual period. Paroxysmal Hsematuria. Uriiie. — Albuminous, alkaline, smoky, blood-coloured, porter- like. Containing heematin, but no corpuscles. See if in subsequent course albumen occurs without blood. Note the colour in relation to the amount of albumen and sp. gr. Dejjosit. — Lithates with high sp. gi\ from renal con- gestion. Blood casts ; renal casts ; epithelial and hyaline casts in Bright's disease ; granular and hyaline in renal congestion. Crystals. JBlood may be mixed with the urine ; in clots ; in clots moulded in ureter. Note quantity of urine, and any difficulty in micturition. DISEASES OF THE URINARY SYSTEM. 191 HiEMATTJRIA. If blood comes from the renal structure usually there are blood- casts and smoky urine ; if from the urinary passages no casts ; if from the bladder or urethra pm-e blood and clots may be passed, usually after micturition. Periodical attacks of discharge of porter-like urine, with granules and hyaline casts, and the deposit of brownish granular matter in place of corpuscles. See paroxysmal hematuria. Hsema- tmia may appear in early inflammation, and in acute exa- cerbations. Occasionally late in cirrhosis. Rare in lardaceous disease. Paroxysmal Hsematuria. — At irregular intervals sudden attacks of rigors, the next urine passed being loaded with blood. Health may long continue good. The paroxysms are un- attended with pain ; there may be a feeling of chilliness across the loins, weakness, nausea, vomiting, joint-pain. The patient becomes languid, Aveak, anaemic. See Anaemia. Examine heart and vascular system. Optic discs. See Haematuria, with description of urine ; Eenal Calculus. / Causation. — It is independent of any known structural change in the kidneys. Supposed to be connected with ague, rheumatism, exposure to cold ; certainly such exposure may excite the paroxysms. It almost always occurs in males, usually adults. There is sometimes oxaluria. 192 CLINICAL MEDICINE AND CASE-TAKING. BRIGHT'S DISEASE, ACUTE. - Sigiis a'od symptoms. — Anasarca. Suppression of urine, more or less complete. Skin harsh. Tendency to somnolence, head-pain, vomiting, coma. Uraemia. Usually after ex- posure to cold or scarlet fever. It may resolve or terminate in a large white kidney. Uri'ive. — Smoky ; very albuminous ; blood discs and large I epithelial casts abundant. In quantity, scanty. Blood "casts. GRANULAR CONTRACTED KIDNEYS. Signs and symptoms. — If any oedema it is slight and transient. Heart hypertrophied ; pulse of high tension. Liability to epistaxis and hgemorrhages from mucous membranes. Albuminuric retinitis. Tendency to uraemia. Commonest in advanced life. Often there is coincident cirrhosis of the liver. Urine. — Clear, with little deposit ; quantity large ; albumen, a trace. Small granular and hyaline casts. Sp. gr. low. FATTY KIDNEYS. Signs and symptoms, — Usually anasarca. Face pale and puffy. Has a fatal tendency. May result from acute Bright's disease. Not uncommon in phthisis. Urine. — Fairly copious ; albumen much. Fatty casts ; fatty cells. Sp. gi\ rather low. AMYLOID KIDNEYS. Sig7is and symptoms. — Anasarca moderate. Pasty anaemic look. Emaciation and signs of amyloid disease of other organs : spleen, liver, intestines. Urine. — Urine copious. Sp. gr. various. Much albumen ; a few hyaline casts. LARGE WHITE KIDNEYS. Signs and symptoms. — Anasarca. Ansemia. Results from acute Bright's disease. Liability to intercurrent acute attacks, with increase of the symptoms. Z7ri7i€.— Scanty ; pale. Casts, hyaline or granular. During exacerbations blood in urine. Albumen. DISEASES OF THE URINAET SYSTEM. 193 BRIGHT'S DISEASE, ACUTE. Kidney enlarged and congested, the wliole structure of tlie organ being involved. Cortex much swollen ; pyramids very dark and congested ; glomeruli large and congested. Epithelium swollen and cloudy. Veins of the surface dilated. GRANULAR CONTRACTED KIDNEYS. Kidney small ; capsule adherent ; surface gTanular and reddish. Frequent cysts in cortex. Much wasting of cortex. Arteries thickened. FATTY KIDNEYS. Kidney large, yellow, pale, soft, easily broken down. AMYLOID KIDNEYS. Kidney large and pale ; surface smooth ; cortex thick ; glomeruli and vessels stain with iodine. LARGE WHITE KIDNEYS. Kidney large, smooth, white. Cortex much swollen from over- development of epithelium in convoluted tubes ; but little change in Malpighian tufts. 194 CLINICAL MEDICINE AND CASE-TAKING. BRIGHT'S DISEASE. ACUTE, CHRONIC. Causation. — Cold. Scarletfever. Anasarca. — Present. Heart and 2^ulse. — No hyper- trophy. There may be pal- pitation in uraemia. OpJithaJmoscojrlc aiojjearances. — Usually no changes. Urine. — Smoky colour. Casts, with large granular epithe- lium and blood. Alcoholism. Gout. Senile degeneration. Present with fatty, amy- loid, and large white kidney ; usually absent with granular kidney. Hyj)ertrophy ; pulse hard. May be haemorrhages or retinitis albuminurica. Hyaline casts, large and small ; granular casts ; fatty casts. Duration of albuminuria. — Many months. Short period. DISEASES OF THE URINARY SYSTEM. ' 195 BLADDER, DISEASES OF. Disease of the bladder and genito-minary excretory apparatus may be indicated by — 1 . Urine, — Thick, with deposit of mucus, pus, phosphates, blood, etc. ; reaction alkaline ; smell offensive. Such urine is passed with cystitis. 2. Micturition clijfficvU. — This may be from stricture of the urethra, a bladder paralysed with retention, or over- flow, or complete incontinence. This may arise fi'om disease of the Spinal Cord or Brain Disease, Meningitis, or Hysteria. 3. Hypogastric pain and tenderness with fever. Cystitis may be acute or chronic. It may result from paralysis or atony of the bladder, calculus, cancer, villous growth. Much mucus renders the urine alkaline by causing the breaking up of the urea into ammonia salts ; phosphates are then precipitated. Cystitis is a common and grave complication of Disease of the Cord ; in such cases it is usually painless. 196" CLINICAL MEDICINE AND CASE-TAKING. RENAL CALCULUS. A clironic condition ; liability to acute attacks. Chronic course. — Aching continuous pain in one lumbar region, shooting downwards. Occasional passage of blood-stained urine, pus, gravel, epithelial debris. Hsematuria, especially- after jolting exercise. There may be tenderness in the loin. Occasional attacks of renal colic. Bladder : there may be signs of stone in the bladder, or Cystitis. Enquire for history of attacks of renal colic, Gout, Uraemia, signs of disease of bladder. Complications. — Stone in the bladder. Nephritic or peri- nephritic abscess. Suppression of urine from impaction of calculus in ureter on each side. Urine. — Quantity. DISEASES OF THE URINARY SYSTEM 197 RENAL CALCULUS. Urine. — Varying on different occasions. It may be mixed with blood, usually not forming clots. Albuminuria usually proportioned to the amount of blood unless the kidneys are degenerated ; then albuminuria may occur in degree over and above the albumen due to the blood. There may be crystals of oxalates or uric acid, etc. Usually no casts. Renal Colic. — Attacks may come on without any previous symptoms of calculus. In the attack paroxysmal j)ain in one lumbar region, severe, causing collapse, vomiting, and sometimes suppression of urine. The attack may cease suddenly ; then the next urine passed may be bloody, and may bring away the calculus per urethram. Such paroxysms especially occur after exertion ; they may last days or weeks. There is often retraction of the tes- ticle on the side of pain (irritation of the genito-crm'al nerve) ; the pain shoots down the inner side of the thigh, and is accompanied by frequent desire to micturate. 198 CLINICAL MEDICINE AND CASE-TAKING. TJIIINE, DESCRIPTION OF. Quantity. — In healthy adult forty to sixty ounces per diem. Colour. — Light or dark sherry ; colourless ; smoky ; blood- coloured. Reaction. — Acid (normal) ; neutral ; alkaline. S2). grr.— Normal, 1015—1025. Urea. — Normal, 400 — 600 grains per diem; 1'5 per cent. tt> 4*0 per cent. Albumen. — Abnormal. See Albuminuria. Sugar. — Abnormal. See Diabetes. Deposit. — Bulk in proportion to urine ; colour ; light or heavy. CHEMICAL EXAMINATION OF THE DEPOSIT. Phosphates. — Soluble in nitric acid ; insoluble in liq. potassse. Urine usually alkaline. Litliates. — Soluble in liq. potassse, or on warming deposits. Urine when warm as passed is clear. Uric acid. — Soluble in liq. potassae, and precipitated from that solution by hydrochloric acid. See Murexide Test. AIucus. — Coagulated by boiling with liq. potassee. MICROSCOPICAL EXAMINATION OF THE DEPOSIT. 1. Casts. — Large, small, hyaline, granular, epithelial, contain- ing large swollen epithelium ; blood casts. 2. Crystals. — {a) Triple phosphate : Triangular prisms, often large ; when very short they may be mistaken for octa- hedral oxalates. (&)Uric acid : Usually coloured ; crystals regular, lozenge-shaped or square, elongated or acicular. (c) Oxalates : Octahedra with bright centres. Dumb-bells. {d) Cystine : Hexagonal plates. 3. E2nthelium. — Glandular ; squamous from vagina or bladder, 4. Fus,— DISEASES OF THE URINAEY SYSTEM. 99 imiNE, DESCRIPTION OF. Qiiantity. — Increased in Diabetes, Colour. — May indicate Jaundice; Hsematuria; greenish n diabetes. Reaction. — In alkaline urine usually a deposit of phosphates. Sx>. gr. — Dense in Diabetes, or if much urea, etc. Low in Granular Contracted Kidneys. Urea. — Usually a large percentage if sp. gr. is high vrithout sugar. Albumen. — May be a transient ingredient, therefore look for it repeatedly. Suga.r. — Occasionally present in Brain Disease. Deposit. — Give general, chemical, and microscopical characters. CLINICAL INDICATIONS OF THE DEPOSIT. Pliosipliates. — Common in hot weather, when urine ferments readilj''. Abundant when there is much mucus or pus. Lithates. — Copious deposit in febrile conditions and in Passive Congestion of kidneys ; also usually in healthy scanty urine. Uric acid. — Like grains of cayenne pepper. May indicate gouty tendency or calciilus-formation. Deranged liver. Mucus. — Copious in cystitis. 1. Casts. — Coming from uriniferous tubes indicate their condi- tion. Numerous in acute Bright' s Disease ; abundant and varied in inflammation ; few in lardaceous disease ; few in cirrhosis ; common in other cases of albuminuria. 2. Crystals. — {a) Triple phosphates are common in alkaline urine in cystitis, and in urine that has decomposed. (&) Uric acid : Deposited in the gouty diathesis, (c) Oxalates : Dyspepsia may produce oxaluria, so anemia, {cl) Cystine may form calculi. 3. Epithelium. — Common in Bright's disease. 4. Pus from a pelvic abscess may be discharged into the bladder or urinary tract. Copious in renal abscess, and in cystitis. 200 CLINICAL MEDICINE AND CASE-TAKING. NORMAL CONSTITUENTS OF URINE. Chlorides. — A few drops of nitric acid, then an excess of solution of nitrate of silver ; white precipitate of chloride of silver thrown down. (N.B. — Mtric acid prevents phosphate being precipitated. ) Wash precipitate and prove its solubility in ammonia. Phosphoric Acid. — (a) Solution of nitrate of silver gives a ■ white precipitate of phosphate of silver, soluble in nitric acid, but insoluble in ammonia. (6) To urine tested as below for sulphuric acid, and thus deprived of sulphates, add excess of ammonia ; phosphate of baryta is thrown down. Sulphuric Acid. — Add a few drops of niti-ic acid, then chloride of darium, which gives a white precipitate of the sulphate. Urea.— If the sp. gr. of the urine be from 1023—1030 it usually crystallizes with an equal bulk of nitric acid, the solution being cooled. Beautiful crystals of nitrate of urea are formed. See quantitative examination. Uric Acid. — Precipitated from urine by hydrochloric a.cid, and waiting twenty-four houi^s. Soluble in liq. potassse. See Murexide Test. (a) Quantity.* — 1. Diminished in early inflammatory conditions. 2. Normal in middle inflammatory stage, and in early . stage of cirrhosis. 3. Increased in lardaceous kidney, and here may precede albuminuria. In cirrhosis, late stage. Sometimes in ad- vanced inflammation and dming absorption of dropsies. 4. Suppressed in acute and adA^anced inflammation, and in advanced cirrhosis. (&) Sp. Gr. and Solids. — Depend upon water, m'ea, other solids. * After Dr. Grainger Stewart. DISEASES OF THE URINARY SYSTEM. 201 ABNORMAL CONSTITUENTS OF URINE. Albumen. — 1, Heat urine, and when boiled add nitric acid ; a precipitate indicates albumen. 2. Float in test-tube on nitric acid ; a non- crystalline cloud at the junction of the two fluids indicates albumen. Sugar: Moore s test. — Mix urine with half its volume of liq. potassse and boil ; a brownish colour shows sugar. Trammer's test. — Add to urine one or two drops of solution of sulphate of copper, then about half as much liq. potassse as urine. If sugar be present, the precipitate at first produced dissolves, producing a blue solution. Now boil this solution ; sugar causes decomposition, and the brown oxide of copper is precipitated. Fehling's test. — Cupric sulphate, 40 grammes; potass, tartrat., 160 grammes; liq. sodee (sp. gr. 1"12), 750 grammes ; distilled water to 1,154*5 c.c. Boil some of this solution ; then add urine, a few drops at first, and if it be saccharine the red suboxide of copper precipitates at once. Bile : Pettenkofers test. — Dissolve a gi'ain or two of white sugar in a drachm of urine ; then add, drop by drop, strong sulphuric acid. A characteristic violet-red colour will be produced if bile be present. Leucine. — A morbid product, crystallizes as small spheres which are composed of acicular crystals which radiate from a common centre. Tyrosine. — Crystallizes in long white needles. 202 CLINICAL MEDICINE AND CASE-TAKING. URINARY CALCULI. Heat a specimen on platinum foil over spirit jfiame ; afterwards witli blowpipe. I. It hurns away, leaving only a minute trace of ash, probably either Uric Acid, Urate of Ammonia, or Cystine. Proceed to test calculus with (a) liq. potassse ; soluble. See Uric Acid. (&) Soluble in hot water or with liq. potassfe, ■ evolving ammonia = urate of ammonia. (c) Insoluble in hot water, but readily soluble in ammonia, the solution on evaporation giving hexagonal plates — Cystine. II. It proves incoinhustihle before the blow-pipe, {a) Soluble in dilute hydrochloric acid = Phosphate of Lime. Ammonia added to such solution gives an amorphous precipitate. (&) Fusible before blow-pipe and soluble in hydrochloric acid = Triple Phosphate. The precipitate produced by ammonia from the solution is crystalline. (c) Before ignition soluble without effervescence in hydrochloric acid, this acid solution giving a white precipitate with ammonia. After ignition soluble with effervescence in hydrochloric acid, this solution giving no precipitate with ammonia = Oxalate of Lime. DISEASES OF Tl^E FRINARY SYSTEM. 203 UEINARY CALCULI. Uric acid and pliospliatic calculi common. Murcxide test of Uric Acid. — Dissolve the substance to be tested in nitric acid, and gently warm ; when cold touch residue with liq. potassee ; a beautiful purple solution indicates uric acid 204 CLINICAL MEDICINE AND CASE-TAKING. SIGNS OF PREGNANCY. General condition. — Chloasma. Nei'vous system. — Head-ache. Altered mental condition, some- times great sleepiness, at other times insomnia. Neuralgic pains of all kinds. Vascular. — Heart beats become more frequent. Pulse of high tension. Ee^piratory, — Dyspnoea on exertion. Cough, reflex. Digestive. — Heartburn, salivation. Nausea may occur at once, but commonly not till second month. Sense of sinking in epigastrium ; cravings for food. Digestive disturbance. — Appetite increased ; may be strangely altered or perverted. Vomiting ; morning sickness. Bowels disturbed ;. piles from pressure ; often consti- pation. Urine. — Kyestein floats as a pellicle on urine after it has stood twenty-four to thirty-six hours, subsequently falling as a milky deposit. Not a sure sign. Albuminuria. Diagnosis from — Ascites ; amenorrhoea from other causes. Ovarian dropsy. Phantom tumour ; abdominal tumour. Duration of pregnancy. — Calculate the full time complete at forty weeks, dating from a fortnight after commencement of last menstruation. SIGNS OF PREGNANCY. 205 PEEGNANCY.— COINCIDENT SIGNS AND SYMPTOMS. Sincial signs of pregnancy. — 1. Suppression of tlie menses, under the climacteric age, and without anaemia or known uterine disease. Balottement. 2. Changes in the breasts which early become somewhat enlarged, their sensitiveness increased, with a feeling of fulness, weight, and shooting pains. Veins in skin en- larged, the glands feeling hard and knotty, and being tender, and sometimes subcutaneous fat augmented. Areola darkened, with a secondary areola outside ; moist with enlarged sebaceous follicles, milk in breast in last month. Nipples turgid and prominent. 3. Changes in abdomen. — No visible tumour till third month. At first umbilicus is sunken from growth of fat ; later it is protruded by internal pressure. Uterine tumour elastic ; very slightly fluctuating ; at fifth month reaches half up to umbilicus. 4. Auscultation of uterus. — Foetal heart. Placental souffle. Complications. — Obstruction of bowels ; haemorrhage from uterus. Pressure signs, — On bladder. Piles. I X D E X Abdomen, examination of, 166 Abdominal cancer, 162 pain, acute, 156 pulsation, 167 tumonr, 166 Acute Blight's disease, 192 Acute yellow atrophy of liver, 179 Addison's disease. 28 Adynamia, see Typhoid state, 44 Ague, 12 Albumen, 201 Albuminuria, 188 latent, 189 Alcoholism, 86 acute, 88 Amnesia, 41 Amphoric respiration, 128 Amyloid degeneration, 24 kidneys, 192 Anaemia, 20 pernicious, 20 Ansesthesia, 57 muscular, 56 Analgesia, 57 Anasarca, 24 Aneurism, 120 abdominal, 169 Angina pectoris, 115 Ankle clonus, 48 Aortic obstruction. 109 Aortic regurgitation, 109 Aphasia, 41 Aphonia, 149 Appetite, 150 Arteries, 122 Arthritis, 34 Ascites, 165 Ascites or ovarian dropsy, 170 Asthma, 146 Ataxy> 94 Atheroma, 123 Athetosis, 52 AiU'a, 57 Auscultation, 128 Bell's paralysis, 61 Bile in urine, 201 Biliary colic, 182 Bilious attacks, 41 Bladder, disease of, 195 Blood in expectoration, 132, 133 motions, 158 urine, 190 vomit, 133, 156 Bone disease, 17, 22 Bowels, state of, 150 obstruction of, 158 ulceration of, 164 Brain disease, 64 Bright's disease, 184 acute, 192 INDEX. 207 Blight's disease, acute or chronic, 194 Bronchitis, 146 Bronzing of skin, 29 Bruit de Diable, 21 Bulbar paralysis, 70 Bulging of chest, 127 Calculi, biliary, 182 renal, 196 urinary, 202 Cancer, 20 abdominal; 162 of intestines, 163 of liyer, 177 of stomach, 163 Cardiac congestion, 106 dilatation, 111 displacements, 112 hyperti'ophy, 110 Casts, urinary, 198 Cerebral meningitis, 82 tumour, 82 vomiting, 45 Chest, movements of, 126 regions of, 124 Children's case-taking, xiv Chlorides in urine, 200 Chorda tympani, 61 Chorea, 76 Choroiditis, 65 Chronic Bright's disease, 192 Circumduction, 54 Cin-hosis of liver, 180 Clonic spasm, 50 Colic, biliary, 182 renal, 197 Coma, 42 Condylomata, 14 Congenital defects of heart, 118 Congenital syphilis, 14 Congestion, passive, 106 Consolidation of lung, 137 Contraction of lung, 136 Convulsion, 50 Co-ordination of limbs, 54 Cough, 130 Cracked pot sound, 128 Cramp, 50 Cranial nerves, 58 Craniotabes, 14 Crepitations, 130 Cross paralysis, 70 Ciystals in urine, 199 Cycloplegia, 67 Cystine, 202 Cystitis, 195 Delirium, 44 tremens, 87 Developmental defects, 31 Diabetes, 28 Diarrhoea, 154 Digestive functions, 150 Dilatation of heart, 110 Diphtheria, 8 Diphtheritic paralysis, 100 Diplopia, 58 Displacements of heart, 112 Dorsal decubitus, 42 Drunkenness, 86 Duchenne's disease, 70 Dyssesthesia, 57 Dysentery, 165 Dysphagia, 156 Dyspnoea, 134 Electric tests, 46 Emaciation, 22 Embolism, 122 Emphysema, 144 Empyema, 139 Enteric fever, 4 diagnosis from tuberculosis, 27 Epilepsy, 78 Epistaxis, 12 Erysipelas, 8 Examination of abdomen, 166 Exophthalmos, 98 Expectoration, 132 Extensors, paralysis of, 70 208 INDEX. Face, paralysis of, 61, 75 Facial nerve, 60 Facial palsy, cerebral, 75 Facial spasm, 50 Fatty kidneys, 192 Feliling's test, 201 Fever, signs of, 2 enteric, 4 scarlet, 4 typh-us, 4 Fevers, specific, 4 Fine movements, 46 Functional paralysis, 47 Gait, 54 Gall-stones, 182 Gasti'ic crises, 94 Gastiic ulcer, 160 General paralysis of insane, 89 Girthing sensation, 57 Glosso-labio-laryngeal palsy, 70 Glosso-pliaryngeal nerve, 62 Goitre, exoplitlialmie, 98 Gonorrhceal rheumatism, 38 Gout, 38 Granular contracted kidneys, 192 Graves' disease, 98 Gummata, 17 Gums, 152 Haematemesis, 156 Hsematuria, 190 paroxysmal, 191 Hfemoptysis, 132 Haemoptysis or Hcematemesis, 133 Haemorrhage in retina, 65 Headache, 41 Head-pain, 40 Hearing, 58 Heart, congenital defects of, 118 dilated and hypertrophied, 110 disease, 112 displacements of, 112 Heart, hypertrophy, 110 physical examination of, i02 Hemiansesthesia, 57 Hemiopia, 41 Hemiplegia, 74 Herpes zoster, 100 Hooping-cough, 12 Hydatids, 183 Hydrocephalus, 84 Hydrothorax, 139 HyperEesthesia, 57 Hyperpyi'exia, 5 Hysteria, 78 Hygienic conditions, 1 Idiots, 19 Illusions, 88 Infantile paralysis, 96 Insanity, 88 Insomnia, 40 Insti'uctions for case-taking, xi additional for children, xiv Intelligence, 40 Intercostal neuralgia, 72 Intermittent hsematuria, 191 Intussusception, 171 Iridoplegia, 67 Iritis, 16 Jaundice, causation, 174 Joints, 34 Knee-jerk, 46 Kidney, tumour of, 167 Kidneys, amyloid, 192 fatty, 192 granular conti'acted, 192 large white, 192 Labio-glosso-larjmgeal palsy,. 70 Laryngeal obstruction, 8, 148 symptoms, 8, 148 Laryngitis, 149 Laryngismus, 52, 149 LarjTix, disease of, 149 INDEX. 209 Lead poisoning, 98 Leucine, 201 Lightning pains, 69, 95 Liver, acute yellow atrophy, 178 cancer of, 176 cirrhosis of, 180 large, 176 small, 178 syphilitic diesase of, 180 Locomotor ataxy, 94 pulse, 104 Lung contraction, 136 solidification, 137 Malformation of heart, 118 Mania, post epileptic, 80 Marasmus, 23 Measles, 6 Melsena, 158 Meningitis, 82 Mercurial tremor, 53 Michel's ganglion, 61 Migraine, 41 Miliaria, 37 Minor paralyses, 70 Mitral obstruction, 108 regurgitation, 108 Motor power, 54 Mouth and throat, 152 Movements of extremities, 54 fine, 46 of head and trunk, 54 Mucous patches, 14 Muscular anaesthesia, 56 movements, hysterical, 78 Murexide test, 203 Nerve, recurrent laryngeal, 62 superior laryngeal, 61 Nervous system, 40 Neuralgia, 70 conditions characterized by, 70 trigeminal, 72 N dules, rheumatic, 37 Normal respii-ation, 128 Nutrition, 22 Nystagmus, 58 Obstruction of bowels, 158 (Edema, 24 pulmonary, 134 Ophthalmoplegia interna, 67 Ophthalmoscopic appearances, 64 Optic discs, 64 atrophy, 64 neuritis, 99 otorrhoea, 58 Ovarian dropsy or ascites, 170 Ovarian tumour, 167, 170 Oxalates, 198 Pain, abdominal, 156 Palate, 152 Palpitation, functional or or- ganic, 114 Palsy of cranial nerves, 58 Paralysis, 46 agitans, 90 diphtheritic, 100 functional and organic, 47 infantile, 96 labio-glosso-laryngeal, 70 of extensors of forearm 98 of face, 61, 75 of face. Bell's, 61 Paraplegia, 68 Paroxysmal hgematuria, 191 Passive cardiac congestio n, 106 Patellar tendon reflex, 48 Pernicious aneemia, 20 Pericarditis, 116 Periostitis, 16 Peritoneum, flidd in, 168 Peritonitis, 172 Phantom tumour, 171 Pharynx, 152 Phlebitis, 123 Phosphates, 198 Phosphoric acid, 200 ^m mm