m. IM %M I GUIS RSCttER, M.D. Columbia SintoergttpV^ in tfje Citp of J^eto §9orfe COLLEGE OF PHYSICIANS AND SURGEONS Reference Library Given by Digitized by the Internet Archive in 2010 with funding from Open Knowledge Commons http://www.archive.org/details/infantfeedinginiOOfisc KARL M, VOQEL NFANT-FEEDING IN ITS RELATION TO HEALTH and DISEASE FISCHER KARL M. VOGEL, M. D INFANT-FEEDING IN ITS RELATION TO Health and Disease LOUIS FISCHER, M.D. Visiting Physician to the Willard Parker and Riverside Huspitals of New York City; Attending Physician to the Children's Service of the New York German Poliklinik ; Former Instructor in Diseases of Children at the New York Post-graduate Medical School and Hospital, etc., etc.; Fellow of the New York Academy of Medicine. Containing 54 Illustrations, with 24 Charts and Tables, Mostly Original TfiURD BDITIOfl Philadelphia F. A. DAVIS COMPANY, PUBLISHERS 1903 COPYRIGHT, 1903, BY F. A. DAVIS COMPANY. [Registered at Stationers' Hall, London, Eng.] Philadelphia, Pa., U. S. A. : The Medical Bulletin Printing-house, 1914-16 Cherry Street. THIS BOOK is DEDICATED TO MY FRIEND, DR. GEORGE F. SHRADY, AS A TOKEN OF RESPECT FOR HIS STERLING QUALITIES AS A MAN AND HIS SINCERITY AS A PHYSICIAN. PEEFACE TO THE THIKD EDITION. This book lias been completely revised; in fact, almost entirely rewritten. Many changes were deemed necessary to aid the general practitioner in working for- mulas required for home-modification of milk. The author has omitted the greater part of the former chapter on Gaertner mother-milk, inasmuch as the milk is not dis- tributed fresh daily, which is so vital. A new chapter, en- titled "Milk Idiosyncrasies in Children," showing how chil- dren were fed who could not tolerate milk, is added. Another new chapter, entitled "Buttermilk Feeding," treating of a method of feeding in vogue in foundling asylums, has been added, as has also a chapter on "Scurvy." The dietary for older children has been enlarged. The method of feeding in diphtheria has been rewritten, and the method in use at the Willard Parker Hospital is de- scribed. A new chapter on "Feeding Children Afflicted with Cleft Palate" has been added. A great deal of attention has been given to the chapter on "Modified Milk from the Walker-Gordon Laboratory." Much of what had previously been written on this subject has been left out. The author believes that accuracy at the laboratory plus clean utensils is of value in many cases, and cites a successful modified-milk feeding. Some illustrations showing specimens of "Poor breast- milk" have been added. In all, this edition may safely be trusted to aid those in search of practical points in modern methods of breast- and bottle- feeding. Louis Fischek. August, 1903. (ix) PEEFACE TO THE SECOND EDITION. This book has undergone a careful revision. A great many chapters have been changed; some have been added, including a new chapter on "Infant-feeding in Summer Complaint." A new diet for an older child, after weaning from the breast or bottle, has also been added. It is also a gratification to the author to note the kindly criticisms which have appeared in the different, medical journals. Many of the suggestions which have been offered for im- proving the practical value of the book have been carefully considered, and numerous additions have been made ac- cordingly. The utility of this book has been manifested by a call for a second edition within six months. Louis Fischer. September 1, 1901. (xi) PEEFACE TO THE FIEST EDITION. During ten years' experience in the children's service of one of the largest children's clinics in this country the author has met with many intricate problems in infant- feeding. Besides this, many points were gained, while studying abroad, through the wise counsel of Professor Adolf Baginsky at the Kaiser and Kaiserin Friedrich Chil- dren's Hospital, in Berlin, both in his hospital wards as well as in the out-patient department. While lecturing on diseases of children at the New York Post-graduate School and Hospital, and later while instructing at the New York School of Clinical Medicine, the author has noted the great anxiety with which his students, all of whom were physicians in active practice, requested detailed information regarding the "Modern Methods of Infant-feeding." • The author has therefore felt that if his experience, aided by the suggestions of many good text-books, were combined to give details pertaining to the feeding of in- fants and children requiring breast-feeding or hand-feed- ing, — so-called bottle-feeding, — then his work would serve as a guide to both the active practitioner and also to the beginner in medicine. Louis Fischer. 65 East Ninetieth Street, New Yokk City. (xiii)' TABLE OF CONTENTS. PART I. PAGE Chapter I.- — Anatomy and Physiology of the Infantile Stomach 1 Chapter II. — Action of Digestive Ferments on Various Bacteria 4 Chapter III. — Stomach-capacity 6 Chapter IV. — Ferments and Their Actions 11 Chapter V. — The Intestinal Canal of the Infant 15 Chapter VI. — Fermentation and Absorption 18 Chapter VII.— Constituents of Milk 25 Chapter VIII. — Bacteria of the Intestine 39 Chapter IX. — Variations of Milk 55 Chapter X. — Chemical Examination of Breast-milk 60 Chapter XL — Breast-feeding and Mixed Feeding 67 Chapter XII. — Wet-nursing and Weaning 76 Chapter XIII. — Management of Woman's Nipples 89 Chapter XIV.— Infant's Weight ' 92 Chapter XV.— Raw Cows' Milk 98 Chapter XVI. — Constituents of Cows' Milk 107 Chapter XVII. — Buttermilk Feeding 115 Chapter XVIII. — Detection and Addition of Preservatives to Milk 122 Chapter XIX.— Cream and Modified Milk 134 Chapter XX. — Water as an Infant's Beverage 142 Chapter XXI. — Bottle-feeding, or Hand-feeding 144 Chapter XXII. — Feeding-table and Cream-mixtures 145 Chapter XXIII. — Home-modification of Milk 148 Chapter XXIV.— Sterilized Milk 169 Chapter XXV.— Pasteurized Milk 177 Chapter XXVI.— Tyndallization 183 Chapter XXVIL— Nipples and Bottles 185 Chapter XXVIIL— Dextrinized Gruels 191 (XV) XVI TABLE OF CONTENTS. PART II. PAGE Chapter XXIX. — Feeding of Infants in Incubators 104 Chapter XXX.— Aerated and Certified Milk 204 Chapter XXXI.— Infant-foods 206 Chapter XXXII.— Milk Substitutes 218 Chapter XXXIII. — Milk Idiosyncrasies in Children 228 Chapter XXXIV. — Laboratory Modification of Milk 23G Chapter XXXV. — Forced Feeding 250 Chapter XXXVI. — Feeding in Diphtheria-Intubation Cases. . 254 Chapter XXXVII. — General Rules for Rectal Feeding 258 Chapter XXXVIII.— Feeding Children Afflicted with Cleft Palate 260 Chapter XXXIX.— Infant-stools 261 Chapter XL. — Nathan Straus Milk-laboratories and Similar Charities 268 Chapter XLL— Colic 271 Chapter XLII. — Constipation 275 Chapter XLIIL— Statistics 286 Chapter XLIV— Rachitis 288 Chapter XLV. — Scurvy 294 Chapter XLVL— Dentition 299 Chapter XLVII. — Athrepsia Infantum (Marasmus) 303 Chapter XL VIII. — Infant-feeding in Summer Complaint .... 317 Dietary 321 List of Books Consulted 346 Index 348 PART L CHAPTER I. Introduction. In order to understand the difference between the various forms of infant-feeding it is necessary to con- sider the anatomy and physiology of the very young digestive tract. The infantile stomach is vertical and cylindrical and the fundus but little developed. Thus, whenever there is a tendency to vomit, the antiperistaltic motions do not press against the fundus, but directly upward. There is, therefore, rather an overflow than a vomiting of the gastric contents; this takes place so easily that the babies are' not disturbed by it. 1 ANATOMY. The muscular development is weakest at the fundus. According to Fleischmann, the oblique and the longi- tudinal fibres described by Henle, which have their origin at the pyloric opening, "do not exist in the infant." The investigations of Leo and von Puteren show that, in spite of this lack of muscular development, the stomach of a nursing infant is emptied in one and a half or two hours. With food that is more difficult to digest, the gastric con- tents are propelled more slowly. The Mucous Membrane of the Stomach. — The mucous glands are far more numerous on the pars pylorica than in adults, whereas they are far fewer in number at the cardia. 1 Jacobi, "Therapeutics of Infancy and Childhood," page 25. (1) 2 INFANT-FEEDING. The mucous membrane of the infant secretes gas- tric juice which, in general, is similar in properties to that of the adult. The amount of secretion in the infant is far less than in the adult, while its chemical constitu- tion is the same, namely: pepsin, lab-ferment, and acids. The exact proportion of the ferment and pepsin has not yet been studied sufficiently to admit of any positive deductions being made. PHYSIOLOGY. It is very important to know that the mucous mem- brane of the mouth is practically dry at birth; the secre- tion of saliva is very small, and, according to Korowin and Zweifel, increases toward the end of the second month. The fermentative (sugar-forming) property of saliva, which is trifling at the commencement, increases with the quantity of the saliva secreted. This is essentially true of other secretions; thus, the pancreatic juice does not have the same emulsifying properties in the infant as in adults. The nursing or sucking centre is located, according to experiments made on animals by Basch, in the medulla oblongata on the inner side of the corpus restiforme. The sucking act is reflex; according to Auerbach, the muscles of the tongue participate most actively. Acids in the Infant's Stomach. — The gastric contents in a nursling contain two acids: (1) hydrochloric acid; (2) lactic acid. The relative acidity is smaller than in adults, the highest point being reached one and a half hours after nursing. According to von Puteren, the acidity is 2 1 / 2 to 3 times as small as in the stomach of adults. According to Leo, the acidity of the gastric juice of nurslings 1 1 / 2 hours after drinking is only 0.13 per cent., whereas, in the adult, after the same time, the acidity is from 1.5 to 3.2 per cent. According to Wohl- mann, free HC1 can be found in healthy nurslings from INTRODUCTION". o 1 V 4 to 2 hours after taking food. The percentage of free HC1 ranges from 0.83 to 1.8 per cent. Lactic Acid. — The quantity of lactic acid is, accord- ing to Heubner, between 0.1 and 0.4 per cent. Pepsin and Hydrochloric Acid. — There are two chief functions of the pepsin and hydrochloric acid which are the same in both infant and adult: First, the power of killing bacteria: a real bactericidal power. Second, as a solvent for albumin. Thus, it is apparent that pathogenic micro-organisms that might have entered the stomach can be destroyed, although we know the small quantity of acid is hardly able to cope with large quantities of food contaminated with bacteria. CHAPTER II. Action of the Saliva on Various Bacteria. Triolo 2 describes a series of interesting experiments with saliva. He first irrigated the mouth with bichloride or permanganate of potash solution, followed this by irrigation with sterilized water until the disinfecting sub- stances were removed, and then inoculated the surface of various culture-media with the sputum. His results proved that saliva possesses a distinct bactericidal prop- erty, for cultures of five-day-old bacteria were destroyed, as well as fresh bacteria eighteen hours old. This property, however, was lost when saliva was filtered. The saliva of the parotid and submaxillary glands, taken singly, were equally efficacious as their combined secretion. He believes that the greatest bac- tericidal action is due to the secretion of the mucous glands in the mouth. The Influence of Gastric Juice on Pathogenic Germs. Gastric juice is, according to the experiments of Drs. Kurlow and Wagner, 3 an exceedingly strong germicidal agent, and when living bacilli get into the intestinal canal it is due to various conditions entirely independent of the gastric juice. When the latter is normal and in full ac- tivity, only the most prolific microbes — such as tubercle bacilli, the bacilli of anthrax, and perhaps the staphylo- cocci^-escape its destructive action; all others are de- stroyed in less than half an hour. Similar influences exist 2 Eivista d'Igiene e di Med. Prat., Neapol. s Vracht; Lancet, March 22, 1890. (4) INFLUENCE OF GASTRIC JUICE. 5 in the intestines, as proved by inoculation with the cholera bacilli. Judging from the results of experiments made by Zagari, Straus, and "Wurtz, who exposed various patho- genic organisms, among others that of tuberculosis, to the action of gastric juice, we must come to the conclusion that, so long as the gastric juice retains a sufficient degree of acidity, tuberculosis of the alimentary canal will be unlikely to occur. 4 4 Canadian Practitioner, April 1, 1890. CHAPTER III. Stomach-capacity. At birth the infant's stomach has a capacity of from 9 to 11 drachms, or 35 to 43 cubic centimetres. At the end of 1 month it is about 2 ounces, or 60 cubic centimetres. At the end of 3 months the gastric capacity is about 4 times the amount at birth. This very rapid increase from birth to this time soon ceases, and the stomach capacity grows in size, but at a much slower rate of de- velopment. (Baginsky.) The series of experiments at the Children's Hospital at St. Petersburg, made by Ssnitkin, showed that the weight, and not the age, determined the capacity of the stomach, and should be used as a guide for the quantity of infant-food required. If the normal (initial) weight of an infant is 3000 to 4000 grammes, or about 6.6 to 8.8 pounds, then 1 / 10 o part, plus the daily increase in weight added, which nor- mally amounts to 2 / 3 to 1 ounce, would give the amount of food required. Biedert also regards the body-weight as an important factor in determining the amount of milk to be given, but Baginsky argues that, while this rule will hold good for a great many infants, he must insist on relying upon the scales to show just how much nutriment has been digested, and thus a regular system of weighing plus the inspection of the stools will aid in establishing the quan- tity of food necessary. "There is no unanimity among experienced clinical observers upon the subject of infant- feeding." Thus, for example, while the great majority of clinicians the world over order milk (cows') in vary- (6) STOMACH-CAPACITY. < ing dilutions, some using the cereals — like wheat, barley, rice, and farina — to dilute and subdivide the curd, other clinical observers — Budin and Variot, Trench observers — advise giving infants at birth whole milk; that is, pure, undiluted cows' milk. The following illustrations will serve to show the difference in the capacity of infants' stomachs at various ages, taken by the author at the morgue of Bellevue Hos- pital : — Fig. 1. — Infant's Stomach, 1 Month Old. Actual Size. From a Case of Malnutrition. Capacity, about 2 Ounces. When Stomach was Filled it Held 4 Ounces Easily. (Author's Collection.) INFANT-FEEDING. STOMACH-CAPACITY. 10 INFANT-FEEDING. CHAPTER IV. Ferments and Theik Actions. In newborn children the parotid alone contains ptya- lin. The diastasic ferment seems to be developed in the submaxillary gland and pancreas after two months at the earliest. Hence it is not advisable to give starchy foods to infants. Ptyalin, the diastase of the saliva, a hydrolytic fer- ment, or enzyme, of the group of unorganized ferments, acts only within a certain range of temperature, being most active at about 40° C. It acts best in a slightly alka- line or neutral medium. Its action is permanently de- stroyed by boiling. Amylopsin, the diastasic ferment of the pancreatic juice, seems to be identical with ptyalin, but it acts much more energetically on raw starch, as well as upon boiled starch; at the temperature of the body the change is al- most instantaneous. At a low temperature this change takes place slowly. According to Musculus, 0' Sullivan, and von Mering, ptyalin and amylopsin change starch and glycogen (ani- mal starch) into dextrin and maltose. Erythrodextrin is first formed, then achroodextrin, and, from achroodextrin, maltose. At 40° C. maltose is slowly changed into dextrose. (Landois and Stirling.) Dextrose and maltose turn the plane of a ray of polarized light to the right. The general term grape- sugar was used formerly to include dextrose (glucose) and maltose. The existence of maltose (though described by Du- brunfaut in 1847) was for a long time doubted until (11) 12 INFANT-FEEDING. O'Sullivan, in 1872, confirmed the previous experiments. (Foster.) In commerce the term "grape-sugar" is applied to the solid product of the "grape-sugar works," the liquid product being known as "glucose." Maltose is the end-product of the action of malt- diastase on starch, and can also be formed as an inter- mediate product in the action of dilute sulphuric acid on the same substance. It also appears to be the chief sugar formed from starch by the diastasic ferments con- tained in the saliva (ptyalin) and pancreatic juice (amy- lopsin). (Halliburton.) The diastasic action of succus entericus, the fluid of the small intestine, is incomparably weaker than ptyalin or amylopsin, and seems only to continue their action. According to SchifT, Busch, Quincke, and Gar- land, it does not form maltose from starch (Eichhorst states that the juice of the large intestine will do this), but changes maltose, which is usually the ulterior prod- uct obtained by the action of ptyalin and amylopsin, into dextrose. The greater part of the maltose is ab- sorbed unchanged. Maltose and dextrose are both crystalline. Bourquelot thinks that the change from maltose to dextrose is due to the action of the intestinal schizo- mycetes, and not to the intestinal juice as such, the saliva, gastric juice, or invertin. (Landois and Stirling.) An important property of dextrose is its power of undergoing fermentations. When an aqueous solution of dextrose is submitted to the influence of yeast, alco- holic fermentation results, yielding alcohol and carbonic anhydride. Lactic fermentation occurs in the presence of decomposing nitrogenous matter, especially of casein, and is probably the result of the action of a specific ferment. The first stage is the production of lactic acid; in the second, butyric acid is formed, with evolu- tion of hydrogen and carbonic anhydride. (Foster.) FERMENTS AND THEIR ACTIONS. 13 Glucose is easily fermentable. (Landois and Stir- ling.) The glucoses are the only sugars capable of direct fermentation; of these, dextrose is more readily decom- posed by yeast than is lsevulose. Certain other sugars are capable of indirect fermen- tation by yeast ; among these are cane-sugar and maltose ; they are first, however, hydrolyzed to glucose. (Jago.) Sucrose (cane-sugar) is not readily absorbed by the intestinal mucous membrane until it has been transformed into glucose. Glucose (like maltose) is taken directly into the cir- culation. (Flint.) The gastric juice slowly changes cane-sugar into glu- cose. According to CI. Bernard, invertin in the intestinal juice converts cane-sugar into invert-sugar, which is a mixture of lsevulose and dextrose. (Landois and Stir- ling.) Dilute acids convert cane-sugar into invert-sugar, which consists of equal parts of dextrose and lsevulose. When subjected to the action of ferments, cane-sugar is first transformed into invert-sugar, then into alcohol and carbonic acid (vinous fermentation). (Battershall.) Succus entericus has been said to change cane-sugar into grape-sugar and by a fermentative action to convert cane-sugar into lactic acid, and this again into butyric acid, with the evolution of carbonic acid and free hydro- gen. (Foster.) Lsevulose is isomeric with dextrose, but it turns the plane of a ray of polarized light to the left; it is non- cry stallizable and ferments with difficulty. (Landois and Stirling.) Lactose, when isolated, is incapable of direct alcoholic fermentation, but milk itself may be fermented. Lactose, however, is directly capable of undergoing lactic and butyric fermentation. (Foster.) 14 INFANT-FEEDING. The theory — which a few years ago was accepted — that carbohydrates, to be absorbed, must be in the form of glucose is now known to be wrong. Lactose and maltose are absorbed without change, and probably some of the dextrins. (Roberts.) Lactose is a readily soluble and diffusible body, and, by virtue of these properties, does not require to undergo change within the alimentary canal to be rendered fit for absorption. (Pavy.) CHAPTER V. Albumin and the Gastric Juice. Another property of gastric juice in infants is the transformation of albumin in the following manner: (1) albumose; (2) then peptone; (3) and lastly syntonin. It is thus apparent that, although the infantile stomach plays a subordinate role as a nourishing organ, it cannot be denied that fluid substances — like water, a solution of salt, and solution of sugar — are absorbed, and in a less degree albumin also. The relative size and capacity of the stomach prevent the function from being as thor- oughly developed as in the adult. Length of Intestine. The relative length of the intestine in nurslings is greater than in adults; so that the intestine is six times as long as the body. Torster believes this is one reason why nurslings receive more nourishment from milk than do adults. The small intestine develops during the first two months of life more than the large intestine, and after the second month the reverse is true. The duodenum remains relatively the longer until the end of the fourth month. The transverse colon is the widest and most elas- tic portion of the large intestine. The continuation of the large intestine in infants into the rectum is indicated by a narrowing at this point. The relative length of the large to the small intestine is stated by Trolowsky to be, in the newborn, 1 to 6; in nurslings, 1 to 5; in adults, 1 to 4. Formation oe Gas in the Intestine. When we consider the lesser development of the mus- cles of the intestine, we can readily understand that peri- (15) 1 6 INFANT-FEEDING. staltic movements are more irregular and less forcible, and that the muscles possess less tone; on this account, there is a larger amount of gas contained in the intestine, which constantly distends it. Thus it is apparent why the abdomen always appears larger in the infant in propor- tion to the other parts of the body. Action of Intestinal Muscles. The action of the intestinal muscles is chiefly to trans- port the food by a series of peristaltic movements. Parts of the intestine are active, while others remain passive. Heubner maintains that post-mortem examinations never show all parts of the intestine in the same condition, owing to the irregularity of the muscular movement. Development of Glandular System. The development of the glandular system in infants is very poor, whereas the lymphoid tissues, follicles, are comparatively well developed. Lieberkiihn's glands are fewer in number than in adults, whereas the Brunner glands in the duodenum are numerous and well developed. The Secretory and Absorbing Power of the Epithelium and the Glands. Heubner maintains that the secretion takes place from cells, located in the small intestine, which are scattered about and are few in number, whereas in the large intes- tine they are far more numerous. Absorption of Pat. The absorption of fat takes place through the intes- tinal epithelium in the duodenum and jejunum; the glands also participate in this action. According to the histological investigations by Baginsky, the real absorbing system of the intestinal wall is found in the connective- ABSORPTION OF FAT. 17 tissue bodies of the mucous membrane of the infantile intestine, in which are located lymphatic vessels con- nected with the larger lymph-channels of the intestine. The physiological and chemical functions are much less developed in infante than in adults because the intestinal glands are relatively less developed. CHAPTER VI. Liver and Bile in Nurslings. The liver in nurslings is relatively larger than in adults. The quantity of bile in the gall-bladder is very small. It is of a golden-yellow color, and has a neutral reaction. Its specific gravity varies from 1.014 to 1.053. Accord- ing to Baginsky, the bile in nurslings contains organic salts, — cholesterin and lecithin, — fat, and various acids in less proportion than in adults. Baginsky was able to demonstrate the presence of glycocholic acid. The pres- ence of a much less quantity of the bile-acids in the in- fant is a beneficial physiological condition. For it is a well-known fact that these acids inhibit the digestive action of the pepsin and of the pancreatic juice. An- other point is that the absence of a bile-acid prevents the assimilation of large quantities of fat, as it is im- possible to split up the fat into fatty acid and glycerin. Thus, fermentative processes are much more frequent in nurslings and appear with greater intensity than in the adult, because of the absence of the biliary acids. The amylacea and all substances containing flour are — owing to the above-described condition of the pancreatic juice and the bile — not fit substances to give the infant, especially during its first three months of life, although very small quantities can be digested, and after the fourth month are not only digested, but also absorbed. Bagin- sky and Sommerfeld found large quantities of mucin in the bile. Unorganized Ferments. The unorganized ferments seem to be nitrogenous bodies; their exact composition is unknown, and it is doubtful if they have ever been obtained perfectly pure. (Landois and Stirling.) (18) UNORGANIZED FERMENTS. 19 Table Showing the Unorganized Ferments Present in the Body and Their Actions. Fluid or Tissues. Ferment. Actions. Saliva. 1. Ptyalin. Converts starch chiefly into maltose. Gastric juice. 1. Pepsin. 2. Milk-curdling. 3. Lactic-acid fer- ment. 4. Fat-splitting. Converts proteids into peptones in an acid me- dium, certain by-prod- ucts being formed. Curdles casein of milk. Splits up milk-sugar into lactic acid. Splits up fats into glyc- erin and fatty acids. Pancreatic juice. 1. Diastasic, or amylopsin. 2. Trypsin. 3. Emulsive (?). 4. Fat-splitting, or steapsin. 5. Milk-curdling. Converts starch chiefly into maltose. Changes proteids into pep- tones in an alkaline medium, certain by- products being formed. Emulsifies fats. Splits fats into glycerin and fatty acids. Curdles casein of milk. Intestinal juice. 1. Diastasic. 2. Proteolytic. 3. Invertin. 4. Milk -curdling. Does not form maltose, but maltose is changed into glucose. Fibrin into peptone (?). Changes cane-sugar into grape-sugar. In small intestine (?). Blood. Chyle. Liver (?). Milk. Most tissues. Di~stasic ferments. Muscle. Urine. Pepsin and other fer- ments. Blood. Fibrin-forming fer- ment. 20 infant-feeding. Organized Ferments. Yeast is the type of the living, or organized, fer- ments. Other living ferments, schizomycetes, seem to be pro- duced from the numerous fungi introduced into the in- testinal canal with the food and drink. (Landois and Stirling.) The action of these organized ferments is now as- cribed to certain minute microscopic organisms ; when the result is the production of some useful body the change is termed "fermentation," and "putrefaction" when the products are useless and offensive. Briefly stated, a liquid free from ferment-organisms or their germs does not undergo fermentation. (Jago.) The lactic fermentation and putrid or butyric fer- mentation of milk are both due to mysteriously minute bacteroid bodies. (Blyth.) The fungi which occur everywhere in the atmosphere are the cause of the spontaneous acidification and subse- quent coagulation of milk. (Landois and Stirling.) The fermentation of carbohydrates, fats, and proteids is believed to be caused by these micro-organisms. Each particular organism has its special product of fermentation. (Jago.) Hydrolytic Agents. These bodies include oxalic and dilute hydrochloric and sulphuric acids. Commencing with soluble starch, these acids possess the power of converting the body first into dextrin and maltose, and then into glucose. The acid hydrolytics also transform cane-sugar into glucose. There is another most important group of hydrolyz- ing agents; these consist of certain soluble bodies of organic origin, and among them may be mentioned hu- ABSORPTION. 21 man saliva, filtered aqueous infusion of yeast, flour, bran, and malt. The following names have been given to active prin- ciples of these hydroly tics : — Name of Hydrolyzing Substance. Constituent. Human saliva. Ptyalin. Yeast. Zymose, or invertin. Flour and bran, especially the latter. Cerealin. Malt. Diastase. (Jago.) Absorption. As most substances in the state in which they are used for food are either insoluble or diffuse but imper- fectly through membranes, complicated digestive proc- esses render these substances soluble and diffusible, and thus fit them for absorption; most of the fats are emul- sionized. The mucous membrane of the intestinal tract from the cardiac orifice of the stomach to the anus is adapted for absorption. In the stomach, watery solutions of salts, grape-sugar, maltose, peptone, and poisons, espe- cially alcoholic solutions of poisons, are absorbed. The empty stomach absorbs more rapidly than one filled with food. Gastric catarrh delays absorption. The greatest area of absorption is undoubtedly the small intestine. (Landois and Stirling.) Table of the More Important Carbohydrates and Their Formulae. Cellulose C 6 H 10 O 5 . Starch C 6 H 10 O 5 or n(C c H 10 O 5 ). Dextrin C 6 H 10 O 5 . Maltose C 12 H 22 O n or C 12 H 2 Ai + H 2 0. Dextrose (glucose, grape-sugar) C 6 H 12 O or C + H 12 H 2 0. Sucrose (saccharose, cane-sugar) C 12 H 22 O u . Lsevulose : C 6 H 12 6 . Invert-sugar C 6 H 12 0<,. Lactose (milk-sugar) C 12 H 22 O n or C, 2 H 22 0„ + H 2 0. 22 INFANT-FEEDING. The sugars are classified into three groups, as given below, with their important members: — (A) Saecharoids (non-fermentable sugars) : — Mannite (from manna) C 6 H 14 8 . Dulcite C 6 H 14 O a - (B) Glucoses: — Dextrose (grape-sugar, starch-sugar) C 6 H 12 O a + Aq. Laevulose (honey) CoHujCV (C) Saccharoses: — Sucrose (cane-sugar) C^H^On + Aq. Maltose (malt-sugar) C^H^Ou + Aq. Lactose (milk-sugar) CJSjaOu + Aq. Cellulose. Cellulose acts mainly as a sort of connective tissue constituting the framework of vegetable organisms. Enzymes. The enzymes, hydrolytic or organic ferments, act only in the presence of water; they are most active between 30° and 35° C, and are destroyed by boiling. (Landois and Stirling.) Hydrolysis. The changes which carbohydrates undergo have been called by the general name of hydrolysis. (Jago.) Hydrolysis, when affected by diastase or its congeners, is termed diastasic action, or diastasis. The ultimate products of diastasis of starch are sugars of various kinds; the process of conversion is frequently termed the saccharification of starch. Soluble Starch. Researches of Brown, Heron, and others make it probable that the formula of starch is more complex than usually expressed by C 6 H 10 O 5 , and the formula n(C 6 H 10 O 5 ) is now used, n expressing the unknown. ACTION OF MALT-DIASTASE. 23 Soluble starch is expressed by the formula 11(0! 2 H 20 - o 10 ). Raw starch is insoluble in cold water, and cannot be dissolved by any known liquid without change, it having a definite organic structure, an outer envelope of cellulose inclosing the starch proper (amylose, or granulose). The cellulose envelopes may be ruptured by mechan- ical means or by boiling in water; in the latter case the containing cellulose bursts, from the interior particles swelling, and the amylose dissolves in the water, forming a viscous liquid (gelatinization). A solution of starch (soluble starch) is colorless, odor- less, and tasteless, but is colored an intense blue by the addition of iodine in extremely small quantities. (Jago.) Dextrin is very soluble in water; it can be prepared from starch by action of heat maintained at a tempera- ture of about 150° C. Starch, boiled with dilute sulphuric acid, will be con- verted into dextrin and maltose, and by continued boiling most of the dextrin and maltose is transformed into glu- cose (dextrose). Action of Malt-diastase. The action of malt-diastase on a solution of starch in water at temperatures from 15° C. to about 70° C. more or less rapidly hydrolyzes the starch into a mixture of dex- trin and maltose. The longer the operation is continued, the higher is the proportion of maltose produced; but even prolonged boiling does not result in any further hydrolysis of the maltose into glucose. Unlike the acids, malt-diastase is incapable of con- verting starch further than into dextrin and maltose. (Jago.) Brown and Heron's results lead to the opinion that there are several dextrins. And these dextrins are di- vided into two groups: erythrodextrins, those first forms; and achroodextrins (reducing dextrins). They also think 24 INFANT-FEEDING. that there is an intermediate body between dextrin and maltose which they call maltodextrin. According to Musculus and Gruber, erythrodextrin is a mixture of dextrin and soluble starch. Dextrin does not undergo alcoholic fermentation ; but, after dextrose is formed from it, the dextrose is capable of directly undergoing vinous fermentation. (Foster, Battershall.) CHAPTEK VII. Fat. Fat contained in milk is no simple compound. It consists of at least nine compounds. More fat is found in colostrum, in evening milk, and in the upper layers of a pail or bowl of milk. Its average percentage is 4.3 per cent.: a great deal more than in human milk. For this reason Jacobi 5 has always taught that "it is better to reduce the fat to be given to infants than to increase it." The deficiency of butter does, however, seriously im- pair the nutritive value of the milk. When there is not enough butter in the milk the casein present is digested with more difficulty, and the result is the same as if the casein were in excess. The plastic (building) materials of food cannot be converted into the tissues of the body without the pres- ence of fat. Fat seems to be essential to the formation of new cells, whose nucleoli always contain fat, and there is more in young and rapidly growing tissues than in those whose growth has been slackened by maturity. From this is evident the immense importance of fat in the nutrition of the rapidly growing infant-body. Sugar. The effects when the amount of sugar is insufficient will be partly the same as when butter is deficient, for the reason that sugar partly supplies the place of butter and partly is converted into fat. Other substances that result from the decomposition of sugar are of importance in many ways. Lactic acid is 5 A. Jacobi, "Intestinal Diseases of Infancy and Childhood," page 87. (25) 2G INFANT-FEEDING. formed in the stomach, helps to give acidity to the gastric juice, and thus assists in the digestion of casein. Milk in which sugar is deficient frequently becomes a source of constipation in the child. (Jacobi.) Carbohydrates. This name is given to a class of compounds contain- ing six, or some multiple of six, atoms of carbon united with hydrogen and oxygen, the latter two in the same proportion as in water, H 2 0; for illustration, the carbo- hydrate, starch, is expressed by (0 6 H 10 5 )n (simplest for- mula). Hydrocarbons. Numerous compounds of carbon with hydrogen are classed under the general name of hydrocarbons; the generic formula CnH 2 n + 2 is applied to such hydrocar- bons as petroleum, marsh-gas, and oils formed by the dry distillation of coal, wood, etc. (turpentine, etc.). Fats. In chemical constitution fats consist of the ethers of the higher fatty acids. Butyrin, or butter-fat, has the formula C 2 H 5 (C 4 - H 7 2 ) 3 . Lard contains palmitin [C 3 H 5 (C 16 H 31 2 ) 3 ] and stearin [0 8 H B (C 18 H 35 C 2 )3]. Castor-oil contains ricinolein [CsB^CigHssOa^] and palmitin (as above). The constitution of many fats and fixed oils is unde- termined. Another source of fat is its formation from albu- minous bodies. (Landois and Stirling.) "While nitrogenous matter is mainly devoted to tissue- formation, the non-nitrogenous alimentary principles — the fats and the carbohydrates — supply the source of power, — are appropriated to force-productions. FATS. 27 The term "hydrocarbons" has been applied by many writers to fats. The fats are a class by themselves. The hydrocar- bons are marsh-gas, benzin and its homologues, and re- semble the fats in many ways, but exhibit decided pecul- iarities, which mark them as a distinct group. The fats have the general formula of C 10 H 18 O. Fats are easily oxidized, yielding heat chiefly, and belong, therefore, to the calorifacient group. There is every reason to believe, however, that fat is essential to tissue-development, as it seems to be in- trinsically mixed up with nitrogenized matter in the ani- mal tissues. Though fats cannot, per se, supply what is required for tissue-development, they, nevertheless, take part in the process. (Pavy.) Fat is absorbed in the form of an emulsion produced by the action of the bile and pancreatic juice; the villi of the small intestine are the chief absorbents, but the epithelium of the stomach and that of the large intestine also take a part. (Landois and Stirling.) The fats and the carbohydrates seem to be quite closely allied. Part of the fat of the body is derived directly from the fat of the food, and it is absorbed and deposited in the tissues. According to Y. Yoit, no fat is formed in the body directly from carbohydrates. Lawes and Gilbert, Heiden and V. Wolff arrived at the conclusion that the carbohydrates absorbed are di- rectly concerned in the formation of fats. "We must as- sume that the carbohydrates are consumed or oxidized in the body and that thereby a non-nitrogenous body derived from the proteids is prevented from being burned up, and that it is changed into fat and stored up as such. ISTo doubt, fat is formed indirectly in the blood in this way. (Landois and Stirling.) 28 INFANT-FEEDING. The balance of evidence seems to be in favor of the view that carbohydrates may be in some way directly con- verted into fat. The characteristic feature of proteid food is that it increases the oxidative, metabolic activity of the tissues, leading to a rapid consumption, not only of itself, but of non-nitrogenous food as well. One value of fats and carbohydrates lies in their being sources of energy, more than three-quarters of the normal income of potential energy coming from them; they are ultimate sources of muscular energy as well as of heat. Their great characteristic is, however, that they do not, like proteid food, excite the metabolic activity of the body, and, therefore, instead of giving rise to bodies demanding immediate excretion from the system, they can deposit their metabolic products as apparently little altered, but in reality greatly changed, fat. (Foster.) Chloride of Sodium (Table-salt). If the chlorides in the blood produce hydrochloric acid, then their necessity is apparent. All infants should, therefore, receive a sufficient quantity of table-salt with each feeding. Brucke states that salt is transformed by electrolysis into hydrochloric acid. 6 Salts. The several saline matters, including the extractives of animal and vegetable food, are no less essential ele- ments of a diet than proteids, fats, or carbohydrates, by reason of their regulating the energy of foodstuffs, more strictly called. They are necessary to life; the body in their absence fails to carry out its usual metabolism, and disease, if not death, follows. 6 Hammersten, "Physiological Chemistry of Digestion," page 185, first edition. SALTS AND WATER. 29 The salts must have important functions in directing the metabolism of the body. The striking distribution of them in the tissues, the preponderance of sodium chlo- rides in blood-serum and of potassium phosphates in the red corpuscles, must have some meaning, though we are in the dark concerning it. Salts and Water. The element phosphorus seems no less important than carbon or nitrogen; the element, sulphur, again, is only second to phosphorus, and is a constituent of nearly all proteids. We know that the various saline matters are essen- tial to health; that when they are not present in proper proportions nutrition is affected; that the properties and reaction of various proteid substances are closely depend- ent on the presence of certain salts; but beyond this we know very little. Last, water has an effect on metabolism, as shown by the fact that, when the water of a diet is increased, the urea is augmented to an extent beyond that which can be explained by the increase of fluid augmenting the facili- ties of mere excretion. (Foster.) Albuminous, or Proteid, Substances. The proteids form a large group of closely related substances, all of which are, perhaps, modifications of the same body. The infant manufactures most of the pro- teids of its ever-growing body from the casein of milk. Their chemical constitution is quite unknowm. Some are soluble, others insoluble, in water. The most important nitrogenized principles used as food are musculin, albu- min, casein, fibrin, gelatin, and gluten. The product of the digestion of such principles in the stomach was called, by Mialhe, albuminose; afterward, by Lehmann, pep- tones. This change renders them not easily coagulable 30 INFANT-FEEDING. and endosmotic, so that they pass through membranes with facility and are readily assimilated after their ab- sorption. (Flint.) Nitrogenous alimentary matter may be said to serve principally for the development and renovation of the living tissues. As to the production of a fat as a result of the split- ting up of nitrogenous matter, it is highly probable that such production takes place, but anything in the nature of proof of this is wanting. The nitrogenous compounds are mainly "histoge- netic," or tissue-forming, materials, but, by the sepa- ration of urea which occurs in their metamorphosis in the animal system, an hydrocarbonaceous compound is left, which may be appropriated to heat-production. (Pavy.) The nitrogenous bodies of milk are not thoroughly understood, and are too frequently classed under one head : proteids. For about five days after calving colostrum is secreted by the mammary glands. This colostrum is poor in fat and sugar, but rich in proteids, which vary between 15 and 20 per cent. These proteid bodies are not well un- derstood, but albumin is about two-thirds of the total quantity. Casein is also present. Colostrum is curdled by rennet, but not as easily as milk. It is interesting to note here that, for commercial purposes, the stomach of a calf under four days old is practically worthless for furnishing rennet. It is well known that large quantities of albumin are absorbed without peptonization; so it would be seen that Nature intended to furnish a very digestible food for the first few days of life. By the fifth or sixth day normal milk is secreted, the change from colostrum to milk being gradual, the quantity of albumin decreasing until in the normal milk it runs about 0.4 per cent. "When the secretion ceases to coagulate on boiling, it is considered milk. PROTEIDS. 31 Proteids. The division, by Baginsky, of the various component parts of milk into fat, carbohydrate, albumin, casein, salts, and water gives a clearer insight into the vital necessities of a growing infant. We have adopted this division from a clinical standpoint, because frequently a chemical re- port of an examination of breast-milk will show "deficient proteids," and hardly convey to the unskilled which vital element is lacking. If, however, deficient albumin and casein were noted, instead of combining the two as one element and calling them proteids, then raw albumin, as the white of egg or yolk of egg, would suggest themselves to remedy the element found wanting. I shall, there- fore, speak of "deficient albuminoids" and "deficiency in casein" rather than combine these elements under the one heading of proteids, which is now being used by so many text-books. A Clinical Method for the Estimation of Beeast-milk Proteids. 7 "Two 'milk-burettes,' each containing 5 cubic centi- metres of milk, are subjected to a temperature warm enough rapidly to sour the milk, and are allowed to re- main in this warmth until a distinct precipitation can be seen. The burettes are then cooled in water, the milk- serum is withdrawn into the graduated tubes, 10 cubic centimetres of Esbach's solution (picric acid, 5 grammes; citric acid, 10 grammes; water, 500 cubic centimetres) are added, the tubes are shaken and centrifugated until constant reading, and the resulting precipitate is read. This reading expresses in percentage the amount of total proteids in the milk. 7 Reprinted in large part from George Woodward's article in the Philadelphia Medical Journal, May 21, 1898. 32 INFANT-FEEDING. "Such is a bare statement of the method. I will briefly take up the various steps in detail. The 'milk- burettes' are made of about 10 cubic centimetres' capacity, and have a glass pinch-cock or valve and a narrow exit- tube about one inch long (Fig. 8). I have tried various forms of burettes and separating funnels, and find this the most satisfactory. A temperature of from 95° F. to 100° F. is the most rapidly effective to produce fermen- tation. This I have conveniently obtained by placing the tubes in a burette-stand and the stand in contact with a radiator. The time required to obtain a distinct precipi- tation of casein is from eighteen to twenty-four hours. Fig. 8. — Woodward's Burette for Estimating Proteids. At the end of this time the milk has distinctly separated into an upper layer of viscid yellow fat; a lower layer of fluid milk, quite opaque above, almost translucent be- low; and, clinging to the sides of the tube, and especially at the bottom, a granular precipitate. The cooling of the milk increases the viscidity of the fat and facilitates its separation from the milk-serum. The milk-serum is re- ceived into 15-cubic-centimetre graduated tubes, the solu- tion of picric and citric acids added up to the 15-cubic- centimetre mark, the mixture stirred with a glass rod and placed in the hand-centrifuge. The amount of centrifuga- tion required is in direct proportion to the care used in separating the fat. If fermentation be watched and the LIME-SALTS IN COWS' MILK. 33 separation be made as soon as the casein-precipitate is dis- tinctly present, the centrifngation to a constant reading may be quickly accomplished." Lime-salts in Cows' Milk. Milk curdles under two entirely distinct sets of con- ditions: (1) it curdles on addition of an acid and (2) it curdles under the influence of rennet (when the reaction of the milk is either neutral or slightly acid). The two varieties of curd which are obtained under these circum- stances may be denominated "acid curds" and "rennet curds/' respectively. Acid curds must inevitably be formed in the stomach after milk has been drunk, if the gastric contents are allowed to become acid. Such curds (we are familiar with them in ordinary life in the form, for instance, of cream cheese or sour milk) are probably not sufficiently firm to set up digestive disturbances. On the other hand, rennet curds (such as we are familiar with in the form of renneted milk and of ordinary cheese) may be extremely firm. It is, therefore, in all probability these rennet curds which set up the familiar infantile dyspepsia of bottle-fed children. If this is so, the facts elicited by Arthus and Pages would appear to be of domi- nating importance in the treatment of these dyspeptic conditions. In order to appreciate this correctly the fol- lowing facts must be attended to: (1) rennet-coagulation is delayed and curdling becomes less and less firm as an increasing proportion of the lime-salts of the milk becomes precipitated as insoluble salts (Arthus and Pages) ; (2) addition of soluble lime-salts (up to a certain maximum) causes increased rapidity of rennet-coagula- tion, accompanied by increased firmness of clot (Arthus and Pages); (3) human milk contains 0.03 per cent, of lime (Bunge); (4) cows' milk contains 0.17 per cent, of lime (Bunge). (Lancet.) 34 infant-feeding. Lime-water and Milk. Dr. Brunn 8 finds the use of lime-water as an addition to milk a frequent cause of constipation and consequent fissures of the anus in children. Any cause which pro- duces diarrhoea, with following constipation, will cause it. Constipation, proctitis, and severe pains on defecation are the results of a fissure. Hernia and masturbation are possible consequences. The condition may be long-last- ing, although it is easily discovered when attention is called to it. He treats it by regulating the diet, by clean- liness, irrigation of the rectum, and by dilation of the sphincter ani, which is easily done. Bicarbonate of Soda in Milk. The addition of the bicarbonate of soda to milk for its preservation has hitherto been tolerated by the police, but the Council of Hygiene of the Seine has condemned the practice, as it is not free from danger. The trans- formation of the sugar of milk into lactic acid gives rise, in milk so adulterated, to a lactate of soda, which is purga- tive, and is thus a cause of diarrhoea in young children. Under these conditions the Council considers that the addition of the bicarbonate of soda to milk, which is an aliment of the first order and very often prescribed for invalids and children, should neither be authorized nor tolerated. 9 Soda is also added to milk sometimes to delay the souring process. The prohibition of this chemical may be viewed in the light of a stultification when we consider the large amount of bicarbonate of soda that is used at the present day in one of the popular methods of feeding 8 Hospitals-tidende, R. 3, B. 8, S. 1089; Medical and Surgical Reporter, February 13, 1892, page 277. 8 Lancet (London), February 11, 1888. MILK-SUGAR. 35 infants. I think it is no less reprehensible on the part of the physician than it is on the part of the dairyman. 10 Milk-sugar. Process of Making. — The milk is collected and al- lowed to stand for several hours in cooling vats; then it is conveyed to a large tank, to be coagulated. Various substances are used to hasten the coagulation. According to Flint, 11 vinegar, cream of tartar, muriatic acid, and sour milk can be used to produce coagulation, but, of course, rennet is the most popular and most commonly used agent. This, as we all know, is the fourth stomach of the calf. The directions given for preparing rennet are as follow: "Care must be taken not to use too much water in cleaning; wiping lightly with a moistened cloth until it is clean is the better way. If then blown up like a bladder and hung up and dried, it will retain its power for coagulating milk for years." Pieces of this rennet are steeped in warm water, and the solution from it is added to the milk and then the milk is raised to a temperature above 100° and kept at that until coagulation takes place. Then the whey is drawn off, and this whey is evaporated by boiling to one-fifteenth of its original mass. This is dipped out into a tub, where the sugar will crystallize in twenty-four to forty-eight hours. These crystals are known as "sand" ; this sand is put into sacks, from which the water drains off. The sand is again boiled in water to a sufficient concentration, and the sugar is allowed to crystallize in sticks. It will thus be seen that many of the other crystallizable bodies contained in milk would be included in this crystallization, as well as the alkaloids or ptomaines. 10 E. E. Brush, M.D., in the Journal of the Amei-ican Medical Association, November 23, 1889. 11 "Milk-cows and Dairy-farming." 36 INFANT-FEEDING. The use of milk-sugar has increased notably during the last few years, in the feeding of children, through the recommendations of Soxhlet and Reubner. It is not gen- erally known, however, that under some circumstances the milk-sugar of cheaper sorts may be contaminated by the presence of bacteria, derived from the milk from which it is made. In repeated examinations the author has found a large number of bacteria, and among them those which lead to the formation of gas: a form particularly feared because of its power to decompose milk. If such milk-sugar be added to sterilized milk it quickly curdles it; if, also, a small quantity of such sugar be added to a sterile milk, and subjected to the usual sterilizing methods for twenty or even forty minutes it is not as certainly rendered free from germs as is the case with ordinary milk. Enough germs, however, are destroyed so that the milk will not spoil until the second or third day. With the Soxhlet method of preparing the milk it was found that a very impure milk-sugar could be used without harm, provided the milk was used up within twenty-four hours. It was quite another matter when, as the author found, certain venders of sterilized milk added the pow- dered sugar after the sterilization process. Through the addition of the impure milk-sugar, countless germs were introduced into the sterile milk, and, since the milk is only slightly warmed before feeding, they enter the ali- mentary canal of the child, where they may produce the very evils one has sought to avoid. Under such circum- stances the use of the relatively sterile beet- or cane- sugar is preferable. From this is derived the practical rule that cheap grades of milk-sugar should be avoided in the prep- aration of the food of infants, or at least that they should be used only before a careful sterilization of the milk. (H. Neumann. 12 ) 12 Berliner klinische Wochenschrift; American Medico-Surgical Bulletin. MILK-SUGAR. 37 Dr. E. E. Brush, 13 of Mount Vernon, K Y., says that "one of the faults of physiological chemists is that they make no distinction between a substance existing in a natural condition and that substance eliminated and iso- lated by chemical means. Thus, the sugar of milk of commerce and the sugar of milk as it exists in that fluid are regarded by the chemists as one and the same thing. Hence, the physician has been led into the error of think- ing that as the sugar in milk is that designed by nature as the best saccharine nutrient, therefore the isolated sugar must fulfill the same function. This is not the truth. Sugar of milk in that fluid is all assimilated, and the milk-sugar of commerce, when added to baby food, is eliminated both by the kidneys and bowels. This I have demonstrated by numerous experiments. I have never found sugar present in the urine or fseces of babies fed at the breast. On the other hand, in three cases of infants fed in twenty-four hours with 3 ounces or more of mix- tures containing commercial milk-sugar (as in Meig's mixture), I have always found sugar in the urine and fasces, demonstrated by Fehling's test." Impurities in Milk-sugar. — J. O. Braithwaite 14 states that the new United States Pharmacopoeia methods of testing milk-sugar do not suffice, because they consider only the contents in grape-sugar and cane-sugar. He found in a great number of samples a disproportionately high residue of ash, which coagulates milk when the latter is heated to nearly the boiling-point. This is a serious defect, since milk-sugar serves now mainly as a material for preparing artificial food for infants. The author found the ash, in several samples, to consist chiefly of magnesium; he found lime in one sample; and concludes that, during the preparation of the sugar, magnesium carbonate and lime had been used for neutralizing the 13 Journal of the American Medical Association, July 5, 1890. 14 London Pharm. Journal, April 14, 1894. 38 INFANT-FEEDING. acid solution, and that, during crystallization, magnesium lactate had crystallized out with the milk-sugar. The author confirmed, by way of experiments, the well-known fact that many metallic and earthy salts coagulate milk, and that magnesium lactate does so also, even in milk- sugar to which 0.5 per cent, of the salt had been admixed. He suggests that the pharmacopoeias restrict the amount of ash from milk-sugar to 0.25 per cent, as a maximum. Bacteria in Milk-sugar. — Prof. Albert R. Leeds 15 states that all the samples of pulverized milk-sugar com- ing from' drug-stores and which he had examined gave an abundant crop of bacteria when definite weights dissolved in sterilized water were submitted to ordinary gelatin- peptone culture; and the presence of bacteria as a com- mon impurity in lactose, to be looked for and avoided by the chemist and the druggist, was sufficiently demon- strated. 15 Journal of the American Chemical Society; Oil, Paint, and Drug Reporter, August 31, 189G. CHAPTER Yin. Bacteria of the Intestine. There are a great many bacteria found in the intes- tine. These are present in a normal infant, as well as in an infant suffering from a gastro-intestinal disorder. A great many of these bacteria are, therefore, non-patho- genic. Miller, who carefully studied the various micro- organisms in the mouth, found that most of them could again be found in the intestinal canal. He also found that certain germs possessed diastasic properties, and were capable of producing lactic-acid fermentation in the milk- fseces of nurslings. Escherich found two germs, the one he called "bac- terium lactis aerogenes (or bacterium aceticum, Bagin- sky)" and the other the bacterium coli commune. In the meconium he found proteus vulgaris, streptococcus coli gracilis, and bacillus subtilis. bacterium coli commune (escherich). Obtained by Emmerich (1885) from the blood, vari- ous organs, and the alvine discharges of cholera patients at Naples; by Weisser (1886) from normal and abnormal human faeces, from the air, and from putrefying infu- sions; by Escherich (1886) from the fasces of healthy children; since shown to be constantly present in the alvine discharges of healthy men, and probably of many of the lower animals. Eound by the author in the blood and various organs of yellow-fever cadavers in Havana (1888 and 1889). Numerous varieties have been cultivated by different bacteriologists, which vary in pathogenic power and to some extent in their growth in various culture-media; (39) 40 INFANT-FEEDING. but the differences described are not sufficiently charac- teristic or constant to justify us in considering them as distinct species. Morphology.— Differs considerably in its morphology as obtained from different sources and in various culture- media. The typical form is that of short rods with rounded ends ; from two to three microns in length and 0.4 to 0.6 micron broad; but under certain circumstances Fig. 9. — Bacterium Coli Cummune. the length does not exceed the breadth — about 0.5 micron — and it might be mistaken for a micrococcus; again the prevailing form in a culture is a short oval; filaments of five microns or more in length are often observed in cul- tures, associated with short rods or oval cells. The bacilli are frequently united in pairs. The presence of spores has not been demonstrated. In unfavorable culture- media the bacilli, in stained preparations, may present unstained places, which are supposed by Escherich to be due to degenerative changes in the protoplasm. Under BACTEJRIUM COLI COMMUNE. 41 certain circumstances some of the rods in a pure culture have been observed by Escherich to present spherical, unstained portions at one or both extremities, which closely resemble spores, but which he was not able to stain by the methods usually employed for staining spores, and which he is inclined to regard as "involution forms." The bacillus stains readily with the aniline colors usually employed by bacteriologists, but quickly parts with its color when treated with iodine solution — Gram's method — or with diluted alcohol. Biological Characters. — An aerobic and facultative anaerobic, non-liquefying bacillus. Sometimes exhibits independent movements, which are not very active. One rod of a pair, in a hanging-drop culture, may advance slowly with a to-and-fro movement, while the other fol- lows as if attached to it by an invisible band (Escherich). The writer's personal observations lead him to believe that, as a rule, this bacillus does not exhibit independent movements. Does not form spores. Grows in various culture-media at the room-temperature — more rapidly in the incubating oven. Grows in a decidedly acid medium. In gelatin plates colonies are developed in from twenty-four to forty-eight hours, which vary considerably in their appearance according to their age, and in differ- ent cultures in the same medium. The deep colonies are usually spherical and at first are transparent, homogene- ous, and of a pale-straw or amber color by transmitted light; later they frequently have a dark-brown, opaque central portion surrounded by a more transparent periph- eral zone; or they may be coarsely granular and opaque; sometimes they have a long-oval or "whetstone" form. The superficial colonies differ still more in appearance; very young colonies by transmitted light often resemble little drops of water or fragments of broken glass; when they have sufficient space for their development they quickly increase in size, and may attain a diameter of three to four centimetres; the central portion is thickest, 42 INFANT-FETCDTNG. and is often marked by a spherical nucleus of a dark- brown color when the colony has started below the surface of the gelatin; the margins are thin and transparent, the thickness gradually increasing toward the centre, as does also the color, which by transmitted light varies from light-straw color or amber to a dark brown. The outlines of superficial colonies are more or less irregular, and the surface may be marked by ridges, fissures, or concentric rings, or it may be granular. The writer has observed colonies resembling a rosette, or a daisy with expanded petals. Escherich speaks of colonies which present star- shaped figures surrounded by concentric rings. In gelatin stick cultures the growth upon the surface is rather dry, and may be quite thin, extending over the entire surface of the gelatin, or it may be thicker, with irregular, leaf-like outlines and with superficial incrusta- tions or concentric annular markings. An abundant de- velopment occurs all along the line of puncture, which, in the deeper portion of the gelatin, is made up of more or less closely crowded colonies ; these are white by re- flected light, and of an amber or light-brown color by transmitted light; later they may become granular and opaque. Frequently a diffused cloudy appearance is ob- served near the surface of the gelatin, and under certain circumstances branching, moss-like tufts develop at in- tervals along the line of growth. One or more gas-bubbles may often be seen in recent stick cultures in gelatin. Upon nutrient agar and blood-serum, in the incu- bating oven, an abundant, soft, shining layer of a brown- ish-yellow color is developed. The growth upon potato differs considerably, according to the age of the potato. According to Escherich, upon old potatoes there may be no growth, or it may be scanty and of a white color. In milk at 37° C, an acid reaction and coagulation of the casein are produced at the end of eight or ten days. In the absence of oxygen this bacillus is able to grow in solu- tions containing grape-sugar (Escherich). In bouillon it BACTERIUM COLI COMMUNE. 43 grows rapidly, producing a milky opacity of the culture- liquid. The thermal death-point of Emmerich's bacillus, and of the colon bacillus from faeces, was found by Weis- ser to be 60° C, the time of exposure being ten minutes. The author has obtained corresponding results. Weisser found that when the bacilli from a bouillon culture were dried upon thin glass covers they failed to grow after twenty-four hours. These results give confirmation to the view that the bacillus under consideration does not form spores. Pathogenesis. — Comparatively small amounts of a pure culture of the colon bacillus injected into the cir- culation of a guinea-pig usually cause the death of the animal in from one to three days, and the bacillus is found in considerable numbers in its blood. But, when injected subcutaneously or into the peritoneal cavity of rabbits or guinea-pigs, a fatal termination depends largely on the quantity injected; and, although the bacillus may be ob- tained in cultures from the blood and the parenchyma of the various organs, it is not present in large numbers, and death appears to be due to toxaemia rather than to septi- caemia. Mice are not susceptible to infection by subcu- taneous injection. Small quantities injected underneath the skin of guinea-pigs usually produce a local abscess only; larger amounts — two to five cubic centimetres — frequently produce a fatal result, with symptoms and path- ological appearances corresponding with those resulting from intravenous injection. These are fever, developed soon after the injection, diarrhcea, and symptoms of col- lapse appearing shortly before death. At the autopsy the liver and spleen appear normal, or nearly so; the kidneys are congested and may present scattered punctiform ec- chymoses (Weisser). According to Escherich, the spleen is often somewhat enlarged. The small intestine is hyper- asmic, especially in its upper portion, and the peritoneal layer presents a rosy color; the mucous membrane gives evidence of more or less intense catarrhal inflammation, 44 INFANT-FEEDING. and contains mucus, often slightly mixed with blood. In rabbits death occurs at a somewhat later date, and diar- rhoea is a common symptom. In dogs the subcutaneous injection of a considerable quantity of a pure culture may give rise to an extensive local abscess. Varieties. — Booker, in his extended studies relating to the bacteria present in the fasces of infants suffering from summer diarrhoea, has isolated seven varieties "which closely resemble bacterium coli commune in morphology and growth in agar, neutral gelatin, and potato, but by means of other tests a distinction can be made between them." These are described as follows: — BACILLUS "d" OF BOOKER. "Found in two cases of cholera infantum and the predominating form in one serious case of catarrhal en- teritis. "Morphology. — Resembles bacterium coli commune. "Growth in Colonies. — Gelatin: Colonies grow lux- uriantly in gelatin, and thrive in acid and sugar gelatin equally as well as in neutral gelatin. In the latter the colonies closely resemble, but are not identical with, the bacterium coli commune. In acid gelatin they differ very much from bacterium coli commune. The colonies spread extensively, and are bluish white, with concentric rings. Slightly magnified, they have a large, uniform, yellow central zone surrounded by a border composed of per- pendicular threads placed thickly together. Sometimes a series of these rings appear, with intervening yellow rings. "Agar: The colonies are round, spread out, and blue or bluish white. Slightly magnified, they have a pale- yellow color. "Stab Cultures. — Gelatin: In sugar gelatin the sur- face growth has a nearly colorless centre surrounded by a thick border, with an outer edge of fine, hair-like fringe; the growth along the line of inoculation is fine and deli- BACILLUS "E" OF BOOKER. 45 cate. In neutral gelatin the growth is not so luxuriant as on sugar gelatin; on the surface it is thick and white, with a delicate stalk in the depth. "Agar: Thick white surface growth, with a well- developed stalk in the depth. "Potato: Luxuriant yellow, glistening, moist, and slightly raised surface, with well-defined borders. ''Action on Milk. — Coagulated into a gelatinous coag- ulum in twenty-four hours at 38° C, and into a solid clot in two days. "Milk-Litmus Reaction. — Milk colored blue with lit- mus is changed to light pink in twenty-four hours at 38° C. The pink color gradually fades, and by the second or third day is white or cream color, with a thin layer of pink on top. The pink color extends in a few days about one-half down the clot. "Temperature. — Grows best about 38° C. "Spores have not been observed. "Gas-production. — Gas-bubbles are produced in milk; not observed on potato." "Found as the predominating form in two cases of dysentery, one of which was fatal and the other a mild case. "Morphology. — Resembles bacterium coli commune. "Growth in Colonies. — Gelatin: The colony growth varies considerably with slight difference in the gelatin. In 10-per-cent. neutral gelatin the colonies resemble those of bacterium coli commune. On the second or third day, when the colonies have just broken through the surface and are spread out, it is impossible to distinguish one variety from the other, but as the colonies grow older a difference can general] y be recognized. In sugar and acid gelatin the colonies have a clear centre with white border. Slightly magnified, a uniform brown centre sur- rounded by a brown zone composed of fine, needle-like 46 INFANT-FEEDING. rays perpendicular to the border. After cultivating for a few generations on acid and sugar gelatin the colonies cease to develop, and either grow in very small colonies or do not grow at all. The activity is regained if culti- vated on neutral gelatin. "Agar : Colonies are large, round, and have a mother- of-pearl appearance. Slightly magnified, a uniform yel- low color. "Stab Cultures. — Agar: Luxuriant, nearly colorless surface growth, with well-developed stalk along the line of inoculation in the depth. "Potato: Golden-yellow, glistening, slightly raised surface, with well-defined borders. "Action on Milk. — Milk becomes gelatinous in twenty- four hours at 38° C, and in a few days a solid coagulum is formed. Milk colored blue with litmus is reduced to white or cream color in twenty-four to forty-eight hours at 38° C, with a thin layer of pink at the top of the culture. The pink color gradually extends lower in the coagulum. "Temperature. — Thrives best at about 38° C. "Spores have not been observed. "Gas-production. — Occurs in milk, but not seen in potato cultures. "Relation to Gelatin. — Does not liquefy gelatin. "Resemblance. — Resembles bacterium coli commune and bacillus 'd,' differing from the former in the charac- ter of the colony growth on acid and sugar gelatin and in ceasing to develop in these media after several genera- tions. It differs from bacillus 'd' in this latter respect." BACILLUS "f" OF BOOKER. "Found in one case of cholera infantum and one case of catarrhal enteritis. "Morphology. — Resembles bacterium coli commune. "Growth in Colonies. — Gelatin: It is difficult to dis- tinguish the colony growth from the bacterium coli com- BACILLUS "f" OF BOOKER. 47 mime. There is often a difference in the colonies planted at the same time and kept under similar conditions, but it is not very marked nor always the same kind of differ- ence. The tendency to concentric rings is greater in this variety. The colonies develop somewhat better on neutral and sugar gelatin than on acid gelatin. "Agar: The colonies are large, round, and bluish white. Slightly magnified, a light-yellow color. "Stab Cultures.- — Gelatin : The culture is spread over the surface and has a mist-like appearance; in the depth along the line of inoculation is a delicate stalk. "Agar: Thick, luxuriant, white surface growth, with a well-developed stalk along the line of inoculation in the depth. "Potato: Bright-yellow, glistening, moist surface, with well-defined borders, and but slightly raised above the surrounding potato. "Action on Milk and Litmus Reaction. — Milk is co- agulated into a solid clot in twenty-four hours at 38° C, and in forty-eight hours is reduced to white or cream color with a thin pink layer on top. "Gas-production. — Gas-bubbles arise in milk cultures, but they have not been observed on potato cultures. "Temperature. — Grows better at 38° C. "Spores have not been observed. "Relation to Gelatin. — Does not liquefy gelatin. "Resemblance. — It closely resembles bacterium coli commune and Brieger's bacillus in the character of its growth upon different media, but is readily distinguished from both, as is also Brieger's bacillus from the bacterium coli commune, by the following differential test recently made known by Dr. Mall: Yellow elastic tissue from the ligamentum nuchse of an ox is cut into fine bits and is placed in test-tubes containing water with 10-per-cent. bouillon and 1-per-cent. sugar, and sterilized from one and one-half to two hours at a time for three consecutive days. Into this is inoculated two species of bacteria, one 48 INFANT-FEEDING. of which is the bacterium under observation, the other a bacillus found in garden earth. The latter bacillus is anaerobic; grows in hydrogen, nitrogen, and ordinary illuminating gas; in the bottom of bouillon; in the depth, but not on the surface, of agar stab cultures, and not at all in gelatin stab cultures. It has a spore in one end, making a knob bacillus. Different species of bacteria — streptococcus Indicus, tetragenus, cholera, swine plague, bacterium lactis aerogenes, bacterium coli commune, Brieger's bacillus, and a number of varieties of bacteria which I have isolated from the fasces — were inoculated with head bacillus into the above-described elastic-tissue tubes. The tubes inoculated with Brieger's bacillus de- velop a beautiful purple tint, which started as a narrow ring at the top of the culture, gradually extending down- ward and deepening in color until the whole tube has a dark-purple color. This color-reaction began in five to fourteen days, and was constantly present in a large num- ber of tests. Tubes inoculated with bacillus '¥ gave a much fainter purple color, which was longer in appearing and never became so dark as with Brieger's bacillus. "Tubes inoculated with the other species of bacteria above mentioned gave no color-change and remained simi- lar to control. Bacillus '¥ also shows a slight difference from bacterium coli commune in coagulating milk and reducing litmus more rapidly, and appears to produce more active fermentation in milk. Like Brieger's bacillus, the gelatin colonies more frequently show a concentric arrangement than those of the bacterium coli commune." BACILLUS "g" OF BOOKER. "Found in one case of serious gastro-enteric catarrh. It was not in large quantity. "Morphology and Biological Characters. — In mor- phology, character of growth on agar, gelatin, and potato, it resembles bacterium coli commune. BACILLI "h" AND "k" OP BOOKER. 49 "Action on Milk and Litmus Reaction. — Milk is not coagulated, and milk colored blue with litmus is changed to pink in a few days, and holds this color. These charac- teristics distinguish it from the bacterium coli commune. "Gas-production. — ISTot observed in milk or potato cultures. "Relation to Gelatin. — Does not liquefy gelatin." BACILLUS "h" OF BOOKER. "Found in one case of mild dysentery, not in large quantity. "Morpliology. — Resembles bacterium coli commune. "Growth in Colonies. — Gelatin: In plain neutral gelatin the colonies resemble those of bacterium coli com- mune. In sugar gelatin the colonies are white and spread extensively. Slightly magnified, they have a round, dark centre surrounded by a yellow, loose zone with an outer white rim; later the whole colony has a uniform yellow color and is not compact. "Agar : Colonies are white, round, and large. Slightly magnified, they are brownish yellow. "Stab Cultures. — Nothing characteristic in gelatin and agar. "Potato culture is yellow, dry, and slightly raised, with well-defined borders. "Action on Milk and Litmus Reaction. — Milk is co- agulated into a solid clot in two days at 38° C. Milk colored blue with litmus is changed to pink in twenty-four hours. "Gas-production. — Occurs in milk; not observed on potato. "Relation to Gelatin. — Does not liquefy gelatin." BACILLUS "k" OF BOOKER. "Found in two cases of cholera infantum and one of catarrhal enteritis. 50 INFANT-FEEDING. "Morphology. — Resembles bacterium coli commune. "Growth in Colonies. — Gelatin: In neutral gelatin the colonies cannot be distinguished from those of bac- terium coli commune. In acid gelatin the colonies do not spread so extensively as those of bacterium coli commune, and they have a decided concentric arrangement; a wide white centre surrounded by a narrow, transparent blue ring; and outside of this a white border. Slightly mag- nified, the colonies have an irregular, yellowish-brown centre, mottled over with dark spots and surrounded by a light-yellow ring bordered by a brownish-yellow wreath. "Agar: Colonies are large, round, and bluish white. Slightly magnified, a light-brownish-yellow color. "Stab Cultures. — Gelatin: In sugar gelatin the sur- face growth is extensive; nearly colorless; and has a rough, misty appearance. In the depth is a delicate growth. In plain neutral gelatin the surface growth is bluish white, thick, and not so extensively spread; the growth in the depth is also thicker. "Potato culture is moist, dirty-cream color, has raised surface and defined border. "Action on Milk.- — Milk becomes gelatinous in twenty- four hours at 38° C, and a solid clot in two days. Milk colored blue with litmus is changed to pink in twenty- four hours, and reduced to white, with a pink layer on top, in two days." BACILLUS "n" OF BOOKEK. "Eound in large quantity, but not the predominating form, in one case of chronic gastro-enteric catarrh (ex- tremely emaciated). "Morphology. — Resembles bacterium coli commune. "Growth in Colonies. — Gelatin: In neutral gelatin the colonies are spread out and have a frosty, or ground- glass, appearance. The centre is blue and border white, but both have the ground-glass appearance. Slightly mag- nified, the central part is light yellow and the border BACTERIUM LACTUS AEROGENES. 51 brown, with a rough, furrowed surface. In acid gelatin the white border is wider and the surface is rougher. "Agar : Colonies are round, blue, or bluish white, and spread out. Under the microscope they have a light-yel- low color. "Stab Cultures. — Gelatin: Has a rough, nearly color- less surface growth, and a thick stalk in the depth along the line of inoculation. "Agar: Thick white surface growth, with well-devel- oped stalk in the depth. "Action on Milk and Litmus Reaction. — Milk re- mains liquid and milk colored blue with litmus is changed to pink. "Gas-production. — ISTot observed in milk or potato cultures. "Relation to Gelatin. — Does not liquefy gelatin. "Spores have not been noticed." 16 BACTERIUM LACTIS AEROGENES. Synonym. — Bacillus lactis aercgenes (Escherich). Obtained by Escherich (1886) from the contents of the small intestine of children and animals fed on milk; in smaller numbers from the faeces of milk-fed children, and in one instance from uncooked cows' milk. Morphology. — Short rods with rounded ends, from 1 to 2 microns in length and from 0.1 to 0.5 micron broad; short-oval and spherical forms are also frequently observed, and under certain circumstances longer rods — 3 microns — may be developed; usually united in pairs, and occasionally in chains containing several elements. In some of the larger cells Escherich has observed un- stained spaces, but was not able to obtain any evidence that these represent spores. This bacillus stains readily with the ordinary aniline colors, but does not retain its color when treated by Gram's method. 16 Sternberg's "Manual of Bacteriology," 1892. 52 INFANT-FEEDING. Biological Characters. — An aerobic (facultative an- aerobic), non-liquefying, non-motile bacillus. Does not form spores. Grows in various culture-media at the room- temperature — more rapidly in the incubating oven. Upon gelatin plates, at the end of twenty-fours hours, small, white colonies are developed. Upon the surface these form hemispherical, soft, shining masses which, examined under the microscope, are found to be homogeneous and opaque, with a whitish lustre by reflected light. The deep colonies are spherical and opaque, and attain a consider- able size. In gelatin stick cultures the growth resembles that of Friedlander's bacillus; i.e., an abundant growth along the line of puncture and a rounded mass upon the surface, forming a "nail-shaped" growth. In old cult- ures the upper part of the gelatin is sometimes clouded, and numerous gas-bubbles may form in the gelatin. Upon the surface of nutrient agar an abundant, soft, white layer is developed. Upon old potatoes, in the incubating oven, at the end of twenty-four hours a yellowish-white layer, several millimetres thick, is developed, which is of paste- like consistence and contains about the periphery a con- siderable number of small gas-bubbles; this layer in- creases in dimensions, has an irregular outline, and larger and more numerous gas-bubbles are developed about the periphery, some the size of a pea ; later the whole surface of the potato is covered with a creamy, semifluid mass filled with gas-bubbles. On young potatoes the develop- ment is different ; a rather luxuriant, thick, white or pale- yellow layer is formed, which is tolerably dry and has irregular margins ; the surface is smooth and shining, and a few minute gas-bubbles only are formed after several days. Pathogenesis. — Injections of a considerable quantity of a pure culture into the circulation of rabbits and of guinea-pigs give rise to a fatal result within forty-eight hours. In his first publication relating to "the bacteria found BACTERIUM LACTUS AEROGENES. 53 in the dejecta of infants afflicted with summer diarrhoea," Booker has described a bacillus which he designates by the letter "b," which closely resembles bacillus lactis aerogenes and is probably identical with it. He says: — "Summary of Bacillus e b.' — Found nearly constantly in cholera infantum and catarrhal enteritis, and generally the predominating form. It appeared in larger quantities in the more serious cases. It was not found in the dysen- Fig. 10. — Bacterium Lactis Aerogenes. teric or healthy faeces. It resembles the description of the bacillus lactis aerogenes, but the resemblance does not appear sufficient to constitute an identity, and, in the ab- sence of a culture of the latter for comparison, it is con- sidered a distinct variety for the following reasons : Bacil- lus 'b' is uniformly larger, its ends are not so sharply rounded, and in all culture-media long, thick filaments are seen, and many of the bacilli have the protoplasm gathered in the centre, leaving the poles clear. There is 54 INFANT-FEEDING. some difference in their colony growth on gelatin, and in gelatin stick cultures bacillus 'b' does not show the nail- form growth with marked end-swelling in the depth. In potato cultures the bacillus lactis aerogenes shows a differ- ence between old and new potatoes, while bacillus 'b' does not show any difference. "Bacillus 'b' possesses decided pathogenic properties, which were shown both by hypodermic injections and feeding with milk cultures." CHAPTER IX. COLOSTRUM. Colostrum is found in the breast of a woman several hours after birth. It resembles milk, but is a much thinner fluid. It is always the forerunner of a healthy normal secretion of breast-milk, which usually appears on the third day after the birth of the infant. Colostrum is the earliest milk, very thin and watery Colostrum- corpuscles Fig. 11.— From a Drop of Milk on the Third Day after Deliv- ery, kindly Furnished by Dr. H. L. Collyer, showing Co- lostrum-corpuscles. The specimen drawn by Dr. Julian W. Brandeis. (Zeiss Ocular 4, dd Lens.) in color, very rich in salts, with decided purgative prop- erties, saving all useless castor-oil, honey, and butter and all sugar-water, with which mothers and nurses delight to experiment. According to Baginsky, colostrum contains large quantities of serum-albumin, is also very rich in fat and colostrum-corpuscles, and contains a large quantity of (55) 56 INFANT-FEEDING. salts. The last two ingredients are supposed to be the cause of the laxative action of the colostrum. Immunity by Breast-milk. It is a well-known fact, and one that has been brought out most prominently by Brieger and Ehrlich and Bagin- sky, that immunity can be conferred on a child by nurs- ing the milk of its mother. This question has also been studied with reference to conferring immunity in infec- tious diseases, and H. Neumann has found that immu- nity can be conveyed to an infant by the agency of breast- milk. The Two Mammary Glands. The two mammary glands of the same woman may yield somewhat different milk, as shown by Sourdat and later by Brunner. Also the different portions of milk from the same milking may have different compositions. The first portions are always poorer in fat (Parmentier, Peligot, and others). According to l'Heritier Vernois and Becquerel, the milk of blondes contains less casein than that of bru- nettes: a difference which Tolmatscheff could not sub- stantiate. Women of weak constitutions yield a milk richer in solids, especially in casein, than women with strong constitutions. According to Yernois and Becquerel, the age of the woman has an effect on the composition of the milk, so that we find a greater quantity of proteids and fat in women 15 to 20 years old and a smaller quantity of sugar. The smallest quantity of proteids and the greatest quan- tity of sugar are found at 20 or from 25 to 30 years of age. The milk with the first-born is richer in water — with a proportionate diminution of the quantity of casein, sugar, and fat — than after several deliveries. The influ- ence of menstruation seems to slightly diminish the milk- sugar and to considerably increase the fat and casein. witch's milk. 57 "Witch's Milk. Witch's milk is the secretion of the mammary glands of newborn children of both sexes immediately after birth. This secretion has, from a qualitative standpoint, the same constitution as milk, but may show important dif- ferences and variations from a quantitative point of view. Schlossberger and HaufT, Gubler and Quevenne, and von Gesner have made analyses of this milk, and give the following results: 10.5-28 p. m. proteids, 8.2-14.6 p. m. fat, and 9-60 p. m. sugar. The newborn human infant almost constantly se- cretes a fluid in the mammas, and adult males have not only secreted milk, but that in abundance enough to suckle. Females, also, both human and animal, occasion- ally secrete milk without having been previously preg- nant. "With regard to the milk secreted by infants, there is some doubt about its real nature. Kollicker does not view it as a true milk, but considers its appearance con- nected with the formation of the mammary glands. Sinety, on the other hand, upon anatomical grounds considers it a true lacteal secretion. It probably is a sort of imperfect milk, loaded with leucocytes, and this is the more likely as Vollard 17 notices that it frequently ends in abscess. Schlossberger gives an imperfect quantitative anal- ysis of a sample of milk obtained by squeezing the breasts of a newborn infant, a male. In the course of a few days about a drachm was obtained. The following was the result of the analysis: — Water 96.75 Fat 0.82 Ash 0.05 Casein, sugar, and extractives 2.83 Sugar-reaction strong. 17 "Traite des Maladies des Enfants nouveau-nes," third edition, 1837, p. 717. 58 INFANT-FEEDING. The most complete analysis we possess of such milk is by von Gesner: — Milk-fat 1.456 Casein 0.557 Albumin 0.490 Milk-sugar 0.956 Ash 0.826 Water 95.705 Total solids 4.295 Joly and Filhol have recorded the case of an old lady, T5 years of age, who suckled successfully her grandchild. Similar instances have been recorded in dogs, and we fortunately possess one or two analyses which show that the fluid is certainly milk. Thus, Filhol and Joly give the following analysis of the milk derived from a bitch which had no connection with a male: — Specific gravity 1.069 Total solids 29.00 Fat 2.20 Sugar 0.32 Albumin 23.20 The ash, on analysis, gave the following percentage : Chloride of sodium 65.10 Chloride of potassium 3.88 Calcic phosphate 27.75 Sodic phosphate 1.40 Sodic carbonate 1.87 Traces of magnesia and other phosphates. Men Suckling Children. Men before now have suckled children. Humboldt relates the case of Francisco Lozano, whom he saw, and whose case he carefully investigated; and it appears MEN SUCKLING CHILDREN". 59 established that this man did secrete from his breasts a nutrient fluid, on which his infant son lived for many months; it is said, indeed, a whole year. The curious in such matters may consult the references given farther on. 18 18 1. "Untersuchung der sogenannte Hexenmilch." J. Schloss- berger, Annalen der Chemie und Pharmacie, B. 87, 1852. 2. Robert Bishop of Cork: letter concerning a man who gave suck to a child. Phil. Trans., 1741, No. 461, page 813, etc. CHAPTER X. Breast-milk. According to PfeifTer, human milk contains, several days after the birth of the baby, a large quantity of albu- min, salt, and a small quantity of fat. He also found 'ors Fig. 12. — This Illustration was Drawn by Dr. J. W. Brandeis from a Drop of Breast-milk Taken from a Wet-nurse Em- ployed in the Author's Family. It Represents a Beautiful Emulsion of Evenly-Divided Fat-globules. Note the Reg- ularity of their Size. that the longer the period of nursing the smaller flic quantity of albumin, which, in the eleventh month, sinks (60) BREAST-MILK. 61 Fig, 13.— Showing a Drop of Milk under the Microscope. Note the poor character of this emulsion, the uneven fat-globules, and their irregular size and distribution. The infant nursed with the above milk was rachitic and colicky. Although 15 months old, no tooth had appeared. The mother of the infant states that she menstruated every twenty-one or twenty-two days since her infant was born — during this present nursing period. Fig. 14. — This Drop of Breast-milk is from a very Anaemic Woman. The child was extremely emaciated; had greenish stools, and colic, and was always crying. Note the uneven character of above emulsion, when compared with Fig. 12. The infant was poorly nourished; had rickets and marked cranio-tabes. Mixed feeding was resorted to, with decided improvement. G2 INFANT-FEEDING. quite low. There is also a decrease in the quantity of salts, whereas the amount of sugar steadily increases. The fat varies constantly. According to Johannessen, the quantity of albumin in the first six months is 1.192 per cent.; in the next six months 0.989 per cent.; and at the end of the year 0.907 per cent. Breast-milk varies according to the length of time that it remains in the breast, and also the length of the nursing period; so it has been shown that the first milk taken at the beginning of the nursing act is the poorest in nutrient value, whereas the last milk is richest in fat. The longer the milk remains in the glands of the breast, the more will the solid substances of the same be ab- sorbed, so that only a watery solution remains. If suck- ing is commenced, this stimulation soon changes the char- acter of this watery milk, so that normal milk will soon be secreted. Forster studied the chemical constitution of the first, middle, and the last portions of milk from a nursing woman, with the following result. In one hundred parts he found: — First Portion of the Nursing Act. Water 90.24 Nitrogenous substances 1.13 Fat 1.70 Sugar 5.56 Ash 0.46 The quantity examined was 33.1 grammes. Second Portion (during the Nursing). Water 89.68 Nitrogenous substances 0.94 Fat 2.77 Sugar 5.70 Ash 0.32 The quantity examined was 33.1 grammes. BREAST-MILK. 63 Third Portion (at the End of the Nursing Act). Water 87.50 Nitrogenous substances 0.71 Fat 4.51 Sugar 5.10 Ash 0.28 The quantity examined was 37.3 grammes. From a study of the foregoing tables we find a decrease of nitrogenous substances during the course of the nurs- ing, a steady increase in the amount' of fat, and an un- varying percentage of sugar. Thus, it is apparent that, in order to submit a specimen of breast-milk to a chemical examination, it is necessary to stimulate the secretory functions of the mammary glands by putting the child to the breast at least two minutes ; thus an even milk can be procured. If this rule is overlooked, then we shall find proportions in the chemical components of milk which might otherwise be entirely different. The most recent chemical analysis of breast-milk shows that in a hundred parts there are: — Solids 11.5 Liquids 88.5 Of the solid constituents there is : — Casein 1.2 to 1.03 Albumin 0.5 Fat 0.8 to 4.07 Milk-sugar 6.0 to 7.03 Ash 0.2 to 0.21 The above is the chemical examination of a good average breast-milk. I again call attention to the fact, however, that not only does the milk vary in different women, but it also varies in the same woman during one single nursing act. G4 INFANT-FEEDING. The albuminoids of milk consist of real casein, lac- talbumin, globulin, and opalisin. This latter body has only recently been discovered by A. Wroblewski, and more recently by Schlossmann. Phosphorus exists in milk as nuclein-phosphorus. Wittmaack has demonstrated the fact that the phosphorus in woman's milk exists as an organic nitrogen compound in the casein. According to the examination of Stolasa, lecithin con- tains a larger quantity of phosphorus in woman's milk than in cows' milk. The specific gravity of breast-milk varies from 1.026 to 1.036. SPECIMEN OF BREAST-MILE: FOE CHEMICAL EXAMINATION. After the third, possibly the fourth, day the average healthy woman secretes milk that gradually becomes nor- mal in quality and quantity, depending on her general condition. It is usual for an infant to lose some weight during its first week of life, owing to various physiological changes, added to which is, no doubt, the deficiency in the quality and quantity of its food. It is a safe plan, and one that I have always urged, if at all possible, to send a specimen of breast-milk to a chemist and submit the same to a chemical analysis. In some women a spec- imen can be examined when the baby is one week old; in others it is better to wait until the end of two weeks. We then would have a proper working basis, and know just how much fat, carbohydrate (sugar), and albuminoids — including proteids — we are feeding. Noting the weight of the child, its sleep, its digestion, color and frequency of its stools, we can easily see in one week how much the infant has gained in weight, and its general condition. To take a specimen, it is advisable to have all utensils absolutely clean; hence the following plan would be sug- BREAST-MILK. 65 gested: Boil an ordinary one- or two- ounce bottle in water, to which a pinch of baking soda has been added, for about one-half hour. Then place the bottle in plain water and boil again for a half-hour. Then turn the bottle upside down, and allow it to drain and dry. In this manner we can completely sterilize the inside of the bottle and avoid contamination. Withdraw a sample of breast-milk by means of a breast-pump. One which has served the author very well is known as the Florence breast-pump, and has a glass mouth-piece. (See illustration, Fig. 17.) Another form is an English breast-pump, having a rubber bulb. Com- pressing this bulb, we can suck about an ounce or more in from five to ten minutes. This milk is to be poured into the bottle, and well corked, and set in a refrigerator, but not on the ice. Milk will keep for many hours in this way. My plan has been to inform the chemist the Human Mjlk. Fat. Pro- TEIDS. Sugar Ash. Authority. Normal Milks. 2.90 3.07 5.87 0.16 A. W. Blythe. 3.68 1.70 7.11 0.20 Marchand. 2.67 3.92 4.37 0.14 Vernois& Becquerel. 3.52 2.01 5.91 Hammarsten. 14 analyses from same woman . 2.53 3.42 4.82 0.23 Simon. Mean of 6, aged 23-33 years . . 3.82 2.04 5.93 0.42 H. Gerber. 3.55 1.52 6.50 0.45 Chevalier & Henry. From woman aged 18 3.20 2.39 683 0.29 J. Bell. From woman aged 33 . . . 2.99 2.51 6.51 0.30 J. Bell. 4 days after deliv- ery . 4.30 3.53 4.11 0.21 Clemm. 9 days after deliv- ery 3.53 3.69 4.30 0.17 Clemm. 12 days after de- livery . . 3.34 2.91 3.15 0.19 Clemm. Average of 84 samples .... 4.13 2.00 6.94 0.20 Leeds. Average of 10 7 samples .... 3.78 2.09 6.21 0.31 Konig. 6Q INFANT-FEEDING. day previous to submitting the sample, so that it can be withdrawn from the breast early in the morning — at about 8 a.m. — and sent to the laboratory at once. The result of the analysis can be received on the evening of the same day or on the following day in all instances. A point worth noting is that the very first milk — known as the foremilk — should not be used, but the infant should be allowed to suck at the breast for about two minutes before pumping the sample. After this the breast-pump should be applied for five minutes to procure the so-called middle milk for examination; then the infant can again be put to the breast to finish the so-called end of nursing or to suck the strippings. CHAPTER XL Bkeast-feeding. During the first month feed every two hours during the day, never oftener. During the second month, every two and a half to three hours. The child may be taken from its sleep during the day to be nursed. Never disturb a child from its sleep at night to be nursed ; so that the rule should be to leave the baby rest as long as it appears satisfied. This rule applies to healthy children only. In sickness special feeding rules are re- quired. If the child thrives, gains in weight, then it is ad- visable in the interest of the mother and child to have an interval of from seven to eight hours at night ; thus Bou- chut advises feeding between 10 and 11 at night and com- mencing the morning meal at 6 a.m. If the child is rest- less, then turn it from side to side ; in other words, chang- ing its position and giving it 1 or 2 teaspoonfuls of boiled water will frequently satisfy it and prolong its sleep. Time foe Feeding. From At Birth 1 Month 2 TO 4 4 TO 6 UNTIL 1 until 2 Months Months Month Months Old. Old. Old. Old. 6 A.M. 6 A.M. 6 A.M. 6 A.M. 8 A.M. 9 A.B1. 9 A.M. 9 A.M. 10 A.M. 11 A.M. 12 Noon. 12 Noon. 12 Noon. 1 P.M. 3 P.M. 3 P.M. 2 P.M. 3 P.M. 6 P.M. 6 P.M. 4 P.M. 5 P.Br. 9 P.M. 9 P.M. 6 P.M. 7 P.M. 12 Mid- 8 P.M. 9 P.M. night. 10 P.M. 11 P.M. 12 Mid- night. 6 to 9 Months Old. 6 A.M. 9.30 to 10 A.M. 1.30 to 2 P.M. 5.30 to 6 p.m. 9.30 to 10 p.m. 9 Months until 1 Year Old. 6 A.M. 10 A.M. 2 P.M. 6 P.M. 10 P.M. (67) 68 INFANT-FEEDING. The first three or four days after birth require special feeding methods: — On the day of the birth, the exhaustion of the mother and presence of colostrum, besides the normal deficient quantity of food in the breast, demand large intervals of rest; thus for the first three days (unless the milk-supply is profuse) putting the infant to the breast once every six hours would be sufficient; if, however, the supply of milk is ample, then we can follow the table given above and nurse the infant every two hours. SUGGESTIONS FOR BKEAST-FEEDING. The mother or wet-nurse should always sit upright, be it at night or during the day, while nursing the infant. Danger of Suffocation. — A great many cases are on record where the mother or wet-nurse has fallen asleep while nursing, and smothered the child. For this reason it is important that the infant should sleep in its own crib or bed, and should never sleep with its mother or nurse. Shall an Infant Receive but One or Both Breasts for One Meal? — This depends on the infant's appetite. Some infants appear satisfied after nursing from one breast, and will let the nipple go and fall asleep. Light tapping on the cheeks of the infant will awaken it, or the with- drawal of the nipple from the infant's mouth will fre- quently arouse the child to continue its nursing. If, however, an infant will not renew its nursing, and still continue to sleep, and if the infant has nursed steadily for ten minutes, then the sleep should not be disturbed. Length of Time for Nursing. — A good plan is to note the time when the nursing act commences and stops. ISTo infant should nurse longer than 20 minutes, whereas fre- quently 10 minutes or 15 minutes will suffice. If an in- fant nurses more than 20 minutes, say 30 or 40 minutes, then we may be sure that the breast-milk is deficient in MIXED FEEDING. 69 quantity, and a specimen should at once be submitted for a proper chemical examination. Mixed Feeding. When there is a deficiency in the quantity of breast- milk, but the quality is good, then it is advisable to feed the infant alternately with breast-milk and bottle-milk. At the same time, it is advisable to direct attention to the mother's general condition, and see if we cannot tone her up, and thus improve both quality and quantity of her milk. Frequently a subnormal or angemic condition re- quires iron; in other cases a day's outing to the sea-shore or to the country, with moderate exercise, will stimulate and increase the flow of milk. It is well to try some galactagogues. Among them the author has found an albumin diet (meat, milk, and eggs) and a preparation known as nutrolactis in tablespoonful doses before meals to have acted very well in some cases. Grandin and Jarman, in their text-book on obstetrics, recommend the strong infusion of galega officinalis when the flow of milk is scant. This is to be ordered in tablespoonful doses three or four times a day. Every drop of breast-milk is so precious that no infant should be deprived of it, and wise is the physician who will insist on giving all the breast- milk when there is deficient lactation, and supplying the deficiency by giving a proper diluted milk- or cream- mixture, adated for the age and weight of the infant. Do Drugs Taken by a Nursing Woman Affect the Baby During the Nursing Period? — Physiological ex- periments have frequently demonstrated the fact that a great many drugs can be given to an infant through its mother's milk; thus, opium and morphine and narcotics in general do affect the nursling when the drugs are taken by the mother. Baginsky calls attention to this fact in his text-book on "Diseases of Children" : "Alcohol, when taken by the mother, is transmitted through the milk, but not in very large quantities. The following is a list of 70 INFANT-FEEDING. drugs which have been found in milk: The purgative principles of rhubarb, senna, and castor-oil; the metals antimony, arsenic, iodine, bismuth, lead, iron, mercury; the volatile oils, like copaiba, garlic, and turpentine ; also salicylic acid, and the iodides and bromides." Do not give cocaine, chloral, atropine, or hyoscyamus. Care is to be used with the .following: Digitalis, antipyrin, and ergot. An unpleasant flavor can be imparted to the breast-milk by the mother or wet-nurse eating onions, turnips, cauliflower, or cabbage. Microbes in the Milk of Nursing "Women. Ringel 19 examined the milk of 25 women, 12 of whom were healthy. With minute precaution to insure accuracy, he found the milk sterile in only 3 cases; he obtained the white staphylococcus in 17, the yellow in 2, the two together in 1 case, and in 2 instances he found the white staphylococcus together with the streptococcus. As the microbes could not be due to genital infection, the idea was suggested that they might come from the child's mouth, the white staphylococcus having been, in fact, found on the child's tongue. But having examined the milk of a woman who had not been suckling, but whose nipples had been disinfected, Eingel still found the staphylococcus. Sterility of Human Milk. Honigmann finds that human milk obtained with all antiseptic precautions from 73 breasts of 64 nursing women was only sterile, when duly cultivated, in 4 cases. In the remainder staphylococcus albus was present, and in 44 cases the staphylococcus aureus; while in 3 in- stances other bacteria — a bacillus and a sarcina — were found. The number of germs varied from 1 to upward "Munch, med. Wochenschrift, No. 27; British Gynaecological Journal, xxxvij Brooklyn Medical Journal, August, 1894. ADDITIONAL FOODS DURING NURSING PERIOD. 71 of 9000 in a cubic millimetre. These observations are of interest in reference to the occurrence of thrush in chil- . dren, to the origin of which they may furnish a clew, and also to the liability that children, while suckling, present to suppuration after wounds accidentally or intentionally inflicted. {Lancet.) Fat-globules. Woman's milk has larger fat-globules than cows' milk. Their number, according to Bouchut, is one to two mil- lions in 1 cubic centimetre. It has less inclination to turn acid; therefore it does not coagulate distinctly. Additional Foods During the Nursing Period. Flour-Ball Feeding. — When an infant nursing at the breast is six months old certain additions to the food can safely be made; thus, for example, the white of a raw egg can be given every second day, and on the alternate day several teaspoonfuls of a meat-soup (beef or chicken) in which barley, farina, or sago has been boiled and strained. This method of feeding can be kept up until the child is seven or even eight months old, and then a small piece of zwieback can be allowed every day. As this is hard, children like to nibble on it, for it seems to soothe their gums. If the bowels are in a good condition, then a few teaspoonfuls of a very light wheat-flour ball can be given every few days. Flour ball can best be made by following the directions given by Dr. Edwin Rosenthal (Paper read before the Pennsylvania State Society, May IS, 1898, entitled "Some Points on Infant-feeding"); he says: "I use the following formula, and I can claim as much good results therefrom as from any form of modi- fied home-made food. It is known as the flour-ball food, commercially imperial granum. It is made as follows: Plain wheat-flour is boiled in a bag for five hours, then dried, broken open, the rind rejected, and then grated into a powder. I take of pure milk, mixed and scalded, 1 pint; 72 INFANT-FEEDING. of sterile water, 1 pint; of the boiled flour, a heaping tablespoonful, a bit of cinnamon-bark (sometimes to give some flavor with certain children), and a pinch of com-, mon table-salt. The milk is placed on the fire and heated ; the flour is rubbed to a fine paste with the water, and then added to the milk. The cinnamon is added, and then it is brought to the boiling-point, taken from the fire, the salt added (not sufficient to taste), and the whole is then placed on the ice. It is then heated again when used. Two ounces every two hours is given to a child one month old. It is increased 1 / 2 ounce every month, while the water is reduced 1 ounce every month. The milk is added to keep the quantity up to the 2 pints. I have with this method seen some very surprising results, and feel no hesitancy in recommending it." The Addition of Hydrochloric Acid to Food.— -The indiscriminate use of dilute hydrochloric acid is a prac- tice that is to be condemned. We know that hydrochloric acid passes through the body unchanged, and in being excreted by the kidneys frequently irritates the same. A point to note is that HC1 is formed in the stomach from the chlorides in the circulation of the blood. It appears, therefore, quite plausible to add salt to the infant's food (ordinary table-salt: ISTaCl), which is likely to be trans- formed into HC1 in the infant's stomach. The Feeding of Sick Children. — The method of feed- ing here is entirely different from feeding in health. xTo definite rules can be laid down as to the quantity or the quality, or the interval required for feeding; for example, if an infant suffering with dyspepsia will vomit, and have large, cheesy curds in the stools, and have anorexia, such an infant requires food that is far more diluted with water than heretofore. If, let us say, an infant, two months old, suffer with dyspeptic disturbance, and receives 2 parts of milk and 3 parts of water, such an infant should be given 1 part of milk with 3 parts of water, to see if the dys- peptic condition cannot be modified. If no improvement THE DIET OF A NURSING MOTHER. 73 is noted after several days of such feeding then it is wise to substitute barley-water instead of plain water, and thus see if the digestibility of the casein cannot be improved. If, however, no improvement is noted, then a good plan is to resort to predigested foods. It is in this class of cases that peptonized foods are so advantageous; but, if milk is badly borne, then it should be diluted with dextrinized gruels. The Diet of a Nursing Mother. Immediately after the birth of the child the exhausted condition of a woman following labor will certainly call for rest; hence sleep is imperative, after which some form of stimulation is required. This can best be accomplished by giving at intervals of several hours good wholesome food, as broth of chicken, or beef-broth, weak tea, or strained gruel. It is unnecessary to state that each woman's case and her former habits must be taken into consideration; and thus, if the labor has been normal, the nourishment will certainly stimulate the flow of milk. , Great care, however, must be given to the usual irritable stomachs in this condition, and, if warm liquids are not well borne, then cold drinks, like buttermilk, koumiss, matzoon, or iced tea, should be employed. In some in- stances ice-cream will aid nutrition and allay gastric irri- tability. If the pelvic condition is normal, then it is wise not to give solid food for the first three days, but, rather, stimulate the milk-glands by giving meat-broths, farina- ceous gruels, and by all means milk. Zwieback soaked in milk or in tea is highly nutritious and easily digestible. Other nutritious foods are calf's-foot or chicken jelly. After the third day — if the pelvic organs are normal — it is wise to consider the action of the bowels. If the bowels have not moved by this time, then buttermilk added to the diet or some stewed prunes or baked apples or stewed peaches, or grapes, will aid in establishing a movement of the bowels. 74 INFANT-FEEDING. If the milk is scanty and the bowels have not acted, then the best remedy is a large tablespoonfnl of castor-oil, modified to suit the taste by the addition of either orange- juice or lemon-juice, or by adding several drops of the ordinary spirit of peppermint. After the bowels have been evacuated and the general condition warrants it, then a diet consisting of the following is indicated: — Bbeakfast, 7 to 8 A.M. Hominy and Milk. Grapes. Farina and Milk. Soft-boiled Eggs. Rice and Milk. Poached Eggs. Oatmeal and Milk. Eggs on Toast. Germea and Milk. Coffee and Milk. Cream of "Wheat and Milk. Tea and Milk. Some Stewed Prunes, Eigs, Cocoa and Milk. or Peaches. Toast and Butter. Stewed Apples. Stale Bread (2 days old), Oranges. with Butter. I do not advise meat or fish in the morning, unless the nursing mother has always been accustomed to this form of diet. LUNCH, 12 TO 1 P.M. Some soup, made from meat — either veal, beef, mut- ton, lamb, or chicken — and containing also some rice, bar- ley, farina, sago, or hominy; it should not be highly sea- soned, and should not be strained. Eish, boiled or fried, and all shell-fish, particularly oysters, are very nutritious during the milking period. If the appetite warrants it, then a piece of steak or chop, roast beef, chicken (white meat only), or raw chopped meat, with bread and butter, is very nutritious. Some fruit. the diet of a nursing mother. 75 Evening, 6 to 7 p.m. A bowl of Oatmeal Gruel. Junket. A drink of milk. Cup of Tea. Farina Pudding. Eggs, if desired. Kice Pudding. Meat, if in the habit of eat- Cornstarch Pudding. ing it in the evening. Some Oysters (stewed). For Thirst. — Cool, filtered water or the alkaline waters, like Seltzer and Apollinaris. If the milk is scanty, the flow can be stimulated by drinking a cup of hot broth, made from beef, chicken, veal, lamb, or mutton, several minutes before putting the child to the breast. Alcoholic Drinks. — If a woman is in the habit of drinking beer or wine, then it is unwise to discontinue the use of alcoholics in moderate quantities, while she is nurs- ing. I have seen a great many women, whose flow of milk was scant, who immediately secreted an abundance of .milk after partaking of a glass of beer or ale or porter with their meals for several days. Beer has a decided laxative effect, and this in itself is rather an advantage for those nursing mothers having a tendency to constipa- tion. So, my rule, therefore, would be to insist on ab- stinence from wine and beer unless the patient has been in the habit of taking it formerly. THINGS TO BE AVOIDED BY A NURSING WOMAN. Onions. Large quantities of pota- Garlic. toes. Cabbage. Butter and fat, except Powerful salts (Eochelle, moderately. Glauber, Epsom). Candies and too much Ethereal oils. sweets. CHAPTER XII. Wet-nukse. If the infant's own mother cannot nurse her child, then we can and should try to secure a wet-nurse. The wet-nurse must be carefully examined, as well as her child, for the presence of syphilis. I beg to refer to a short paper on this subject, published in the Amer- ican Medico-Surgical Bulletin in January, 1894. 1. Never have a baby fed by the milk of its mother if the latter suffer with general debility or tuberculosis. Extremely nervous mothers should not nurse their babies. Syphilitic babies (hereditary) can only be nursed by their own mothers, owing to the risk of infecting the wet- nurse. In such cases very frequently the life of the child is dependent on its being nursed by its mother. The following general rules may be noted: — (a) The return of menstruation is no contra-indication to the continuation of nursing. (b) The moment a woman is pregnant nursing should be stopped. (c) Children should not be nursed at night unless for some special reason. (d) Weaning should take place gradually, and only in the eighth to the tenth month. (e) It is understood that weaning should not be com- menced during the hot summer weather. The main factor in determining the time of weaning is "weighing." Children must be weaned when, although in perfect good health, they remain below normal weight. (/) Prolonged nursing will induce rachitis. 2. If, for various reasons, a child cannot be nursed by its own mother, we then resort to the wet-nurse. (76) WET-NURSE. 77 (a) She must be carefully examined as to her phys- ical condition ; tuberculosis, all chronic disorders and diseases would prevent proper nursing. Hereditary nervous troubles, epilepsy, or syphilis would exclude nursing. (b) It is a good point to try to procure a wet-nurse suckling a child about as old as the one we wish her to nurse, although it is quite common to find nurses who have older children than the one they wish to nurse and to find the latter doing well. (c) The proof of the usefulness of the wet-nurse is the condition of the baby after some time. If the child thrives, it will increase in weight. Hence scales must be frequently used. DIET OF A WET-NURSE. The diet given for a nursing mother can also be used as a guide in choosing the diet for a wet-nurse. The greatest care, however, must be bestowed on the Manner of Living. — If a wet-nurse was formerly a servant, or worked out-of-doors and is suddenly taken into this new mode of life and given charge of a baby, she must have proper exercise, or she will very soon secrete milk totally unfit for an infant, and, as a result, the child will probably have severe colic and irregular, cheesy stools; will vomit excessively, and will not gain suffi- ciently in weight. It is, therefore, important to try to adapt a wet-nurse to the same condition as existed prior to her pregnancy, so that both her manner of living and, chiefly, her diet shall not be different. Proper Rest. — To be equal to her task a nurse must be given plenty of sleep, if it is at all possible. Adriance, in the Archives of Pediatrics, says: — 1. Excessive fats or proteids may cause gastrointes- tinal symptoms in the nursing infant. 2. Excessive fats may be reduced by diminishing the nitrogenous elements in the mother's diet, 78 INFANT-FEEDING. 3. Excessive proteids may be reduced by the proper amount of exercise. 4. Excessive proteids are especially apt to cause gastro- intestinal symptoms during the colostrum period. 5. The proteids, being higher during the colostrum period of premature confinement, present dangers to the untimely-born infant. 6. Deterioration in human milk is marked by a re- duction in the proteids and total solids, or in the proteids alone. 1. This deterioration takes place normally during the later months of lactation, and, unless proper additions are made to the infant's diet, is accompanied by a loss of weight, or a gain below the normal standard. 8. When this deterioration occurs earlier, it may be the forerunner of the cessation of lactation, or well- directed treatment may improve the condition of the milk. Methods of Changing the Ingredients in "Woman's Milk. ]Rotch gives a condensed table for these changes as follows : — To Increase the Total Quantity. — Increase the liquids in the mother's diet, especially milk (malt-extracts may be helpful), and encourage her to believe that she will be able to nurse her infant. To Decrease the Total Quantity. — Decrease the liquids in the mother's diet. To Increase the Total Solids. — Shorten the nursing intervals, decrease the exercise, decrease the proportion of liquids, and increase the proportion of solids in the mother's diet. To Decrease the Total Solids. — Prolong the nursing intervals, increase the exercise, and increase the propor- tion of liquids in the mother's diet. WET-NURSING. 79 To Increase the Fat. — Increase the proportion of meat in the diet. To Decrease the Fat. — Decrease the proportion of meat in the diet. To Increase the Proteids. — Decrease the exercise. To Decrease the Proteids. — Increase the exercise up to the limit of fatigue for the individual. It is wise in all cases of disturbed lactation, whether in maternal or wet- nursing, to make efforts in accordance with these rules to produce a milk that is suitable for an infant who is not thriving, before changing to any other method of feeding. Wet-nursing. It is an established fact that the best possible food for an infant is breast-milk. Where the mother of an infant is prevented from nursing her child, the next thing to be considerd is wet-nursing. That nursing a child is an advantage to the mother is a well-known fact, inas- much as it influences the contraction of the uterus and stimulates the circulation. Contrary to the belief that nursing a child is detrimental, and contra-indicated in women whose lungs are weak and who have a tendency to the development of tuberculosis, it does them no harm, and, indeed, seems to do them good. This statement is borne out by the experience of Dr. Heinrich Munk, of Karlsbad, Austria, a specialist for diseases of women. In Austria the State supports public institutions for lying-in women. They are kept there and confined gratis, and remain about fourteen days. They are admitted into these hospitals in the last months of pregnancy. Vienna usually has about 300 women on hand. Prague con- stantly has 100 women in this condition, who are utilized for the purpose of instruction to physicians and midwives. In Prague there are about 3000 women confined annually, and these women are put into the foundling- 80 INFANT-FEEDING. asylum. There they remain until they procure a place as a wet-nurse or as long as their services are needed in the asylum. When wet-nurses are taken from the found- ling-asylum, it is a frequent occurrence to have those remaining therein nurse at least two children, and fre- quently three, at one time. In this manner they dispense gradually with these wet-nurses without hurting the re- maining children. Many children die, some of them intrapartum in operative confinements, and the women (mothers of such children) are then utilized for wet- nursing. It is a rule to keep the children in the asylum until they have attained a little over four kilogrammes (about 9 pounds), and they are then put out for further feeding (artificial feeding), for which the city pays about 12 florins a month ($5.00). The children remain usually until they are six years old, and are then given back to their own mothers. Many of these children die, others are adopted by those who have reared them, but the greater portion are taken back by their own mothers. In Vienna there are about 10,000 confinements annually in the public institution. There are a great many cities in Austria — like Innsbruck-Olmutz, Brunn, Linz, and Klagenfurt — where there are at least 200 confinements annually. In Vienna a wet-nurse receives 30 florins per month, for which she is sent (railroad expenses paid) to whoever requires her services. She is taken on trial for fourteen days, to see if she is adapted for her place. A wet-nurse can be procured by sending a telegram and a money-order any day during the year. The customary wages are from 12 florins upward per month. Each wet- nurse is -carefully examined by the professor before she is sent away. A great many families do not care to take a wet-nurse from an asylum, as they are usually women in the lowest walks of life, and prefer, therefore, to take a woman who has been married. Tor this purpose there are wet-nurse agencies, duly licensed. These will supply wet-nurses, and usually take orders in advance; thus a WET-NURSING. 81 wet-nurse may be reserved. Suck wet-nurses cost much, more, and those from one special region — Iglau in Mahren — receive from 20 to 50 florins monthly. The empress took for her own use a wet-nurse from Iglau (a married woman), and the Princess of Bulgaria took a wet-nurse from Iglau for her last child. Not only Iglau, but the whole region, is renowned for its excellent quality of wet-nurses. The Bohemian and Mahren nurses have very good mamma?. They seem to love the children intrusted to them. While it is a rule that a wet-nurse should be taken for a baby of the same age as that of her own, frequently wet-nursing of an infant at birth by a wet-nurse whose baby is three months old has not been followed by any bad results. In !STew York we are at a decided disadvantage re- garding wet-nurses. As no licensed agencies exist, a few people having so-called influence procure wet-nurses by friendship, or something similar, from superintendents and house physicians where obstetrical work is done. Thus we find ourselves at the mercy of some people who traffic in wet-nurses for a fee, usually five dollars, and who do not stop at anything to attain their own selfish ends. Time and again have I sent for a wet-nurse to an agent who, instead of giving me a healthy wet-nurse, tried to induce me to use women having colostrum-milk for an infant in which such milk would have proved disas- trous. In another instance, only recently, I procured a wet- nurse from an agent who sent me one 17 years old, who had had a premature birth, "evidently an abortion," and whose milk was typical thin water, with here and there a fat-globule, when examined under the microscope. At other times some of the finest specimens of wet- nurses have also been procured from the same agent. It is a pity that we have no municipal control for what 82 INFANT-FEEDING. the writer considers one of the most valuable adjuncts to our maternal feeding, and such control would also regu- late the supply to such unlimited number that modern arrogance on the part of the wet-nurse would probably disappear. The prices paid in New York are from twenty to thirty dollars per month and board, and this price pro- hibits many an infant from securing the benefits of Nature's food. Let us hope for municipal regulation. 20 Weaning, and Feeding fkom One Year to Fifteen Months. Weaning should take place gradually between the eighth and tenth months. In some instances it is advis- able to commence weaning a child much sooner; for ex- ample, when there is a deficiency in the supply of milk or owing to ill health of the infant's mother. This I have already mentioned in the section on "Mixed Feed- ing." Weaning is imperative when the infant's mother is pregnant, although it is advisable to use great caution if it occur in midsummer. In a case of this kind the better plan would be to have a specimen of the breast-milk ex- amined by a chemist, and, if the same be found deteri- orated in quality, then the judgment of the physician must prevail as to the advisability of continuing or dis- continuing the nursing. My rule has been not to wean during the summer months. The main points have already been mentioned in this chapter under "Wet-nurse." Weaning should not be attempted suddenly. Thus, it is better to commence weaning gradually, by withdraw- ing the breast in the morning and substituting a bottle for that meal. Following this meal we can again nurse 20 The attention of the Department of Health has been directed to this condition in New York. WEANING, AND FEEDING AFTER WEANING. 83 the child at the breast for two feedings, and substitute a bottle for its fourth meal instead of the breast. In this manner we can feed the child with a bottle in the morn- ing, to be followed in three or four hours by the breast, then at the next feeding again nurse the child, and this to be followed in three or four hours by the bottle: — 8.00 a.m Bottle. 11.30 a.m Nursing. 3.00 p.m Nursing. 6.30 p.m Bottle. 10.00 p.m Nursing. In this manner we can see just how the food is as- similated, and also study the individual peculiarities of the baby. Some children are very hard to wean, and it will require great tact and patience to successfully cope with this condition. In consultation I recently saw a child which, on being removed from the breast, absolutely refused to take the bottle, and when fed with a 'spoon the child would spit out its food. After three or four days of this unsuccessful weaning the physician attempted more heroic methods, and insisted on isolating the child from the wet-nurse for twelve consecutive hours. This infant refused to take food even after that time, and then it was that I was summoned. We decided to give pep- tonized milk, alternating with peptonized yolk of egg by means of rectal feeding. Thus, 1 ounce of milk and 1 ounce of starch-water were injected, followed four hours later by the peptonized yolk of egg added to the starch- water. This method of feeding can be found de- scribed in detail in the chapter on "Rectal Feeding," and also in the chapter on "Feeding in Diphtheria In- tubation Cases." Thus we aimed to sustain life and avoid starvation. The rectal feeding was continued for two days more, when the child suddenly took the bottle. 84 INFANT-FEEDING. In some cases forced feeding by gavage will be found useful. If the child holds its jaws firmly, the catheter can be introduced through the nasal passage, as described in the section on "E"asal Feeding." I was called to see a perfectly healthy child, about 9 months old, whose mother told me that "he would not take the breast." She was greatly chagrined, but all efforts at nursing him proved futile. The infant had weaned himself. Such cases of "self-weaning" are very rare. When weaning is successfully accomplished, then great care must be exercised, owing to the change in diet. It will be found that the slightest error in over- feeding or too frequent feeding will be rewarded by a severe attack of dyspepsia and the usual gastric disturb- ances, such as vomiting and fermentation in the stomach, causing diarrhoea and possibly colic. It will therefore be very necessary to exercise good judgment in the choice of both quality and quantity of food during the first month or two after weaning or until the stomach adapts itself to this new way of feeding. The amylolytic func- tion now being thoroughly developed, we can safely give cereals. TIME OF FEEDING. Excepting in rare instances, after a child is weaned it should not be fed oftener than once in four hours. The best time for feeding would be about 6 a.m., 10 a.m., 2 p.m., 6 p.m., and 10 p.m. if the child is awake. This would give eight hours rest, and healthy children can be trained to sleep that length of time. The first bottle after sleeping should consist of 8 ounces of pure cows' milk. 21 This would be the 6-a.m. feeding. Four hours later, or at 10 a.m., the infant should 21 The best milk obtainable in this city is undoubtedly milk received in bottles direct from the dairy the same day of milking. WEANING, AND FEEDING AFTER WEANING. 85 receive the white of a raw egg, fed with a spoon from a wine-glass, immediately before its bottle, which con- sists of: — Cows' milk 5 ounces. Barley-water 2 ounces. At 2 p.m. our next feeding should consist of 8 ounces of pure cows' milk. I usually permit the infant to nibble on a small piece of the ordinary zwieback. The evening meal at 6 p.m.: — Cows' milk 6 ounces. Barley-water 2 ounces. The last feeding, at 10 p.m., if the child is awake, or at midnight should consist of 8 ounces of pure cows' milk. When milk is brought from the dairy there is a thick layer of cream on the top of the milk, which should be thoroughly mixed with the milk by shaking the bottle, so that the infant receives a thoroughly mixed milk contain- ing the same quantity of cream in each feeding. The milk should be mixed and the barley-water added to it. It is then poured into thoroughly clean bottles, which are stoppered with ordinary cotton stoppers. This can be found described in detail in the chapter on "Sterilization." This food is to be steamed for twenty minutes and then allowed to cool by placing the bottles in a refrigerator, but not on the ice. When ready for use each bottle is to be warmed to a temperature of about 100° F. for the feeding. If constipation follows the use of this diet, then a good plan is to substitute 2 ounces of oatmeal-water instead of the barley-water above mentioned. When the stools are regular and the child appears to be quite pale, then great good can be accomplished by adding 2 ounces of almond-milk instead of the oatmeal- or barley- water: The preparation of almond-milk can be found described in the "Dietary," to which I beg to refer my readers. If 86 INFANT-FEEDING. a severe form of constipation, with cheesy curds in the stools, exists, then the milk should not be steamed, but fed in the "raw state." It is understood that it should be warmed to the body-heat before feeding to the infant. Instead of giving the white of egg every day I substitute either 1 or 2 ounces of a good beef-soup or chicken-soup or beef-tea and expressed steak-juice, and feed this quan- tity immediately before the 10-a.m. bottle of milk. No distinct change of food will be necessary until the child is twelve or fifteen months old, when I am in the habit of giving either 1 / 2 saucer of oatmeal-gruel with some butter or some hominy and butter in addition to a morning bottle. In the evening, when the child arrives at this age, a half-dozen teaspoonfuls of junket can be fed before the evening bottle of milk. When a child is over one year or about fifteen months old, instead of giving water for thirst I frequently give prune-water made by boiling good fleshy prunes in water for one-half hour and strain- ing off the liquid. When oranges can be procured, one or more teaspoonfuls of orange-juice can be given with advantage. Apple-sauce can also be given. Thus, my plan consists in giving each one of these foods on different days. Just at this period the addition of several tea- spoons of Mellin's food has been found very beneficial. Owing to gastric derangements, it will be found necessary to frequently discontinue milk entirely. At such times the use of the milk-foods — such as Nestle's food — has proved very beneficial. When diluting milk with cereals like barley-water, rice-water, sago-water, flour-ball and water, it is always better to dextrinize the diluents. This dextrinization has a decided effect on the casein, inasmuch as it splits up the curd, rendering it finely flocculent as it is found in human milk, and it is especially indicated in the period of weaning after the stomach has been ac- customed to breast-milk and is suddenly forced to digest cows' milk containing a more rubbery and heavier casein, or curd. FEEDING AFTER WEANING. 87 Diet After the Period of "Weaning. The following dietary, one of each course, is to be given to a child one and a half to three years old : — breakfast, 7 to 8 a.m. " Sliced apple with cream. Baked apple or apple-sauce. Sliced banana with cream. 1. Fruits ^ Sliced peaches with cream. Oranges. Fleshy prunes. Grapes. Hominy. Farina. Oatmeal. Cream of wheat. Germea. Indian (or corn) meal pudding. Wheaten grit. A soft-boiled egg. A scrambled egg. 4. Water, cocoa, or chocolate to drink. 5. Toast and butter, wheat-broad and butter, or grape- jelly- NOON MEAL, 12 TO 1 P.M. 1. Soup made with lentils or split peas, meat, and vegetables, but not highly seasoned. Thicken soup by adding either sago, farina, barley, or rice. The last should be omitted if severe constipation exists. Broiled fish; white meat only. Raw scraped steak. Broiled top sirloin. j Broiled tenderloin. | Lamb chops. ^ Breast of chicken. 2. Cereals 3. Eggs INFANT-FEEDING. Spinach. Mashed potato. Baked potato. Stewed corn. Mashed peas (without skins). [ Cauliflower. 4. If the appetite warrants it, some fruit mentioned in the breakfast list may be given. 3. Vegetables <{ l I EVENING MEAL (LIGHT) 5.30 TO 6.30 P.M. [ Crackers and a bowl of milk. T , ! Bread and a bowl of milk. Luncheon < ~ , , , , „ .,, j Custard and a glass 01 milk. [ Junket and a glass of milk. f Cornstarch. j Tapioca. 2. Puddings <{ Rice. Farina. Zwieback. Oysters or fruit. CHAPTER Xni. Management of "Woman's Nipples. the management oe the nipples before the baby is born. It is very important during the last few months of pregnancy to devote considerable time and attention to the condition of the nipples. If these be found long and round, well projecting, then it is advisable to try to harden them, because the irritation from the child will cause considerable trouble unless we seek to prevent this. Fig. 15. — Nipple-shield for Relief of Tender Nipples. For this purpose wash, in winter, with lukewarm water to which some alcohol has been added (2 - teaspoonf uls of alcohol to a cup of lukewarm water). In summer cold water will be found more agreeable, using the same quan- tity of alcohol. If the nipples are very small and flat, and do not protrude properly, then suction by means of a breast-pump, applied directly over the breast, will draw them out. In some instances an ordinary clay pipe which has a smooth bowl, the bowl to be laid over the (89) 90 INFANT-FEEDING. nipple and the stem to be sucked or drawn, is saticfac- tory. This is to be repeated every few days. A few minutes of drawing out will suffice until the nipples are sufficiently prominent. Biedert 22 gives the following prescription for hardening the nipples: — Tannic acid 1 teaspoonful. Red wine 8 ounces. If red wine is not handy, then substitute brandy in its stead. This is to be applied after thorough washing with soap and water, and removing crusts, if they are present. TENDER NIPPLES. If, while nursing, the nipples crack and blood oozes from them, or if, from irritation of the child's gums biting them, the nipple is sore, then it is a good plan to allow the child to nurse through a nipple-shield. (See Fig. 15.) Nipple-shields can be used during the nursing act, and immediately thereafter the following salve can be smeared on the nipples: — R Zinc oxide, 1 drachm. Vaselin, 1 ounce. — M. BREAST-PUMP. The breast-pump (Figs. 16 and 17) is a valuable ad- dition to the nursery. It should be kept scrupulously clean by immersing it in boiling water containing a pinch of table-salt. In drawing a specimen of breast-milk for a chemical examination the breast-pump is very useful. If an infant is ill and refuses the breast, — as, for example, if it has rhinitis or cold in the head, nasal obstruction, preventing it from breathing while the nipple is in its mouth, — it generally will take the breast and immediately 22 "Kinderernaehrung," fourth edition, 1900, page 110. BREAST-PUMP. 91 let go of it again. If the breast-pump is properly applied, and the required quantity of milk drawn off, the infant can frequently be fed slowly with a spoon. Fig. 16. — Breast-pump. In a serious condition, — as, for example, in a severe case of pneumonia with loss of appetite, — the life of the child may depend on forced feeding. This will be de- Fig. 17. — Breast-pump. scribed in the section on "Gavage." It is very important to have the cup or any other receptacle into which we draw the breast-milk properly sterilized; Otherwise the breast-milk will be infected in the same manner as has been described in detail in the sections on "Cows' Milk" and "Bottle-feeding." CHAPTEE XIV. Infant's "Weight. When a child develops normally, at either breast- or bottle- feeding, then it increases from 6 to 8 ounces each week for the first two or three months. This gain is slightly lessened toward the end of the fifth or sixth month; but if a child thrives, then its gain, be it ever so small, must be steady from week to week. We have distinct data on which to base our calculations, and any variation from the normal should be carefully investi- gated. If a child is breast-fed, and suddenly ceases to gain in weight, then a chemical examination of the breast- milk is imperative to know just what ingredient is want- ing. If the child is bottle-fed, and the weight does not increase, then the formula is improper and frequently the addition of a larger quantity, or sometimes the changing of the quality, — as, for example, several ounces of cream instead of several ounces of milk, — will give the baby the requisite amount of food. Table Showing the Gain in a Healthy Infant Fed at the Breast. ISTormal weight at birth, Gain at the end of the first 7 lb. week, ISTone. Weight when 2 weeks old, Gain at end of 2 weeks, 7 lb. 6 oz. Weight when 3 weeks old, 7 lb. 14 oz. Weight when 4 weeks old, 8 lb. 6 oz. (92) 6 oz. Gain at end of 3 weeks, 8 oz. Gain at end of 4 weeks, 8 oz. infant's weight. 93 The vital factor is certainly the general condition of the infant, whether it is bright and playful, sleeps quietly, and the condition of its stools. "When the latter are normal as to color and frequency, then we may be sure that the baby is thriving. During the second month the infant should gain about 8 ounces per week; roughly speaking, an ounce per day is a good average. During the third month a child should gain an ounce per day, or about 2 pounds per month. After the third month, an infant usually gains about 3 to 4 ounces per week; so that if a child has doubled its weight at the end of the fifth month, such a child should be considered normal, if the other conditions warrant such an opinion. An infant should weigh three times its weight at birth by the end of its first year. Taking seven pounds as the average weight for an infant at birth, it should weigh 14 pounds at the end of five months and 21 pounds at the end of its first year. Weighing Immediately After Nursing to Determine the Quantity of Milk an Infant has Taken. — When scanty milk-supply is suspected in either the nursing mother or in a wet-nurse, then we can, in some instances, resort to weighing immediately after the baby has nursed. It is understood that the child must be weighed both immediately before nursing and then immediately after nursing. The difference in weight is the amount of milk swallowed. "While this may serve in some cases, the author has not found it very practical, and cannot recommend it, excepting in rare instances. It is well known that an infant whose stomach is filled requires rest after nursing, and the less it is handled the less is the chance for expelling its food. Thus, my advice is not to handle or fumble with a child after nursing, but rather aid Nature in resting an infant than to try to provoke vomiting by unnecessary handling. 94 INEANT-FEED1NG. Difference in Weight Before and Immediately After Nursing. — An infant should weigh, if under 3 months Fig. 18. old, 3 ounces more after nursing, and in older children, 5 to 6 months, it should weigh at least 6 ounces more after suckling. WEIGHT-CHART FOR AN INFANT. 95 Weight-chart for an Infant. Week after Birth. Date of Weigh- ing. Weight of Child with Clothes Weight of Clothes Body- weight Kind of Food ; Quan- tity and Frequency of Feeding. Stools On the birthday. After 1 week . . 2 weeks . 3 weeks . 4 weeks . After 5 weeks . 6 weeks . 7 weeks . 8 weeks . After 9 weeks . 10 weeks . 11 weeks . 12 weeks . After 13 weeks . 14 weeks . 15 weeks . 16 weeks . After 17 weeks . 18 weeks . 19 weeks . 20 weeks . After 21 weeks . 22 weeks . 23 weeks . 24 weeks . After 7 months. 8 months. 9 months. 10 months. 11 months. 12 months. 96 INFANT-FEEDING. Properties op Human Milk. Appearance. Specific Gravity. Reaction. On Boiling. Coagulates. Bluish, semitransparent, no odor, sweetish. 1.26 to 1.36. Amphoteric, relation of alkalinity and acid- ity as 3 to 1. Does not coagulate, and forms a very thin, hardly-perceptible skin. At ordinary temperature after several hours. Coagulates on addi- tion of Lab-fer- ment. Coagulates imperfectly in small isolated flakes, which do not precipitate as a uni- form coagulum. Fat. Yellowish white, resembling cow-butter. Specific gravity at 15° C, 0.966. Melts at 34° C. Varieties of Fat. Butyrin, palmitin, stearin, olein, myristin, caproin. Behavior of Various S Few volatile acids. More than half of the Acids. ( non-volatile consist of oleic acid. Milk-plasma Casein. Composition of Albu- minoids. Difficult to precipitate with acids and salts. The precipitate redissolves in excess of acids. During pepsin digestion there is (_ no pseudonuclein produced. Lactalbumin and lactoglobin; relation of casein to albumin, 0.5 to 1.2 or 1 to 2.4; of the 1.3 per cent, albumin, there are 64 parts of casein, and 37 parts of globulin I. and albumin. Solids. Less solids than in cows' milk, especially CaO— P 2 O s . Quantitative Analy-r Water8741 . alb uminoids, 2.29; fat, 3.78; sis, according to Soxhlet milk-sugar, 6.21; solids, 0.31. Bacteria. Usually sterile, rarely staphylococcus albua and aureus. PROPERTIES OF COWS MILK. 97 Appearance. Specific Gravity. Reaction. On Boiling. Coagulates. Properties of Cows' Milk. i Opaque white or whitish yellow, in thin layers bluish white, slight odor, faintly sweet. 1.28 to 1.36. {Amphoteric; relation between alkalinity and acidity, 2 to 1; Soxhlet maintains that cows' milk contains three times the acidity of human milk. f Does not coagulate and forms a skin con- \ taining casein and lime-salts. {Coagulates very soon, owing to lactic-acid formation. Coagulates on addi- tion of Lab-fer- ment. Fat. Varieties of Fat. Behavior of Various Acids. Coagulates to a solid mass at body-tem- perature, from which a yellowish fluid can be expressed. Yellowish-white mass. 0.949 to 0.996. Sp. gr. at 15° O, Milk-plasma Casein. Composition of Albu- minoids. Solids. Quantitative Analy- sis, according to Soxhlet. Bacteria. r Palmitin, olein, stearin, myristin, caprilin, caprin, caproin, butyrin, laurin, lecithin, cholesterin, and yellow coloring matter. Volatile fatty acids, about 70 per cent.; • not volatile, 0.3 to 0.4 per cent, of oleic; the remainder consists of palmitic and stearic chiefly. Easy to precipitate with acids and salts; excess of acid does not dissolve; belongs to the nucleo-albumin group. Less lactalbumin and globin; the largest portion of the albuminoids is casein. Relation of casein to albumin, 0.3 to 3.0, or 1 to 10. Cows' milk contains more solids than hu- man milk. Water, 87.17; albuminoids, 3.55; fat, 3.69; milk-sugar, 4.88; solids, 0.71. Contains all milk bacteria, frequently also pathogenic bacteria, as typhoid, diph- theria, and tubercle bacilli, etc. CHAPTER XV. Raw Cows' Milk. The ideal cows' milk is clean, raw milk. By this is meant milk free from all possible contamination. Such milk should he obtained from a stable having all modern hygienic surroundings. If greater attention were be- stowed on the condition of the cow, the cow's udder, the stable, the bucket, the hands of the milker, then less ster- ilization and pasteurization would be necessary. For let it be distinctly understood that certain chemical changes are brought about in milk when it is steamed, be it in the process of sterilization or pasteurization. Neither pasteurization nor sterilization adds to the digestibility of milk. Indeed, clinical experience has demonstrated the fact that raw milk, known in some places as certified milk, in the milk-laboratories in New York City as guaranteed milk, is more easily assimilated, as proved by the condi- tion of the stools as well as the gastric digestion. Nature has given us a good example of how milk should be fed to an infant. Breast-milk is certainly raw milk, and is served to the infant at the temperature of the body. Not only does boiling or steaming milk pro- duce chemical changes in the albuminoids, but it renders the process of digestion much more difficult, and thus it is that most infants taking boiled milk suffer with con- stipation. This is not so, however, in the case of infants fed on raw milk. When sterilized milk or pasteurized milk is found to disagree with children, raw milk may sometimes be easily assimilated. Thus it will be found that, while boiled milk or sterilized or pasteurized milk, given either whole or with its proper dilution to suit the various ages, (98) RAW COWS' MILK. 99 will provoke constipation, by substituting raw milk in- stead of the heated milk the same will be more easily assimilated. The author has frequently noted decided antiscorbutic properties in fresh raw milk. In children with pronounced rickets, and even scurvy, the withdrawal of sterilized or other milk and the substitution of fresh raw milk will work surprising changes. Biedert, in his fourth edition of 1900, page 184, states that he has followed Escherich and Epstein, who recommend giving full milk to children at birth. In Erance Budin and H. de Rothschild, and more recently E. Schlesinger, in Germany, have given undiluted milk to both sick and well children as a substitute for breast- milk. Biedert claims to have seen good results in some instances, but cannot recommend whole milk, as a rule, for feeding children. Marfan, another advocate of pure- milk feeding, believes that milk should be diluted until the fourth or fifth month, but later he advises pure-milk feeding. Schlesinger, of Breslau, while giving pure milk gives a longer interval between the meals. That the greatest possible success is not achieved by this method of feeding in France can be judged by the statement of Marfan while discussing the subject of athrepsia. He says: "N'a jamais vu V athrepsie confirmee se terminer favor 'dblementP Thus it seems that even we have much better results than the French, for there are certainly a great many children who can and will digest a diluted milk, and thin milk- and cream- mixtures, as shown by their stools, their sleep, and their increase in weight. These same children with enfeebled digestive functions will invariably show gastric disturbances, — such as vom- iting, colic, constipation or diarrhoea, restlessness, sleep- lessness, — and will cry continually; besides, they do not increase in weight. This method of feeding has been tried over' and over again, and we are compelled to dis- continue the heavier food, consisting of pure milk, and to substitute a light food, consisting of diluted milk. 100 infant-feeding. Fkesh Raw Milk. Just as the medical profession, and to some extent the laity, have become thoroughly impressed with the idea that milk should be boiled before being used, to insure the destruction of the microbes which it contains, Dr. Freudenreich comes forward with a series of experi- ments, by which he claims to prove that fresh raw milk possesses remarkable germicidal properties. According to his experiments, the bacillus of cholera, when put into fresh cows' milk, dies in an hour, the bacillus of typhoid fever succumbs at the end of twenty-four hours, while other germs die at the end of varying periods. Milk which has been exposed to a temperature of 131° F. loses its germicidal properties. Milk which is four or five days old is also devoid of microbe-killing power. 23 Raw-Milk Assimilation. Vasilieff, 24 in an inaugural thesis of 1889, in St. Petersburg, details experiments made on six healthy in- dividuals, varying from 18 to 23 years of age, restrict- ing them for three days to a diet of fresh milk, and then for the three days following to boiled milk. The author claims that his experiments have proved that the assimi- lation of the nitrogenous principles of the boiled milk is considerably less than of fresh milk, although the differ- ence is less marked than in the case of the fats. Never- theless the feces contain considerably more fatty acids after the administration of boiled milk than after the use of fresh milk. He therefore concludes that the nutritive value of boiled milk is much inferior to that of fresh milk. He explains these differences by the hypothesis, "Bacteriological World, December, 1891; Journal of the Ameri- can Medical Association, February 27, 1892. 24 Journal de Medecine, May 4, 1890; Therapeutic Gazette, June 16, 1890. SCURVY. 101 first advanced by Schmidt, that, by boiling, a part of the casein in cows' milk is transformed into hemialbuminose. Scukvt. A paper on "The Uses and Prospects of Pathology," delivered at the opening of the Section in Pathology at the recent annual meeting of the British Medical Asso- ciation, by Dr. W. Howship Dickinson, senior physician and lecturer on medicine at St. George's Hospital, states that a disease which presents itself as of chemical origin, if one due almost certainly to a specific deficiency in the constituents of the food may be so regarded, is scurvy, of which the chemical secret has apparently been so readily exposed that the chemical antidote ought to be almost within our grasp. The conditions which give rise to sea- scurvy are generally known. It is not probably as widely recognized that scorbutic affections are so common on shore, among infants brought up by hand, that this form of land-scurvy is scarcely less important. It is to be at- tributed to the exclusion of fresh milk by various arti- ficial preparations used in its stead. Not that these prep- arations are in themselves injurious, but they are insuffi- cient. Milk in its fresh state, and of good quality, whether from biped or quadruped, is antiscorbutic; preparations or sophistications of it are not so, or not so to a sufficient extent. Scorbutic hematuria and scurvy-rickets are but too frequent consequences of this substitution. We know the broad result, which is enough for practice, but we do not know the isolated want. What does fresh milk con- tain which is so essential and so difficult to preserve? We no more know this than what there is in lemon-juice to be antiscorbutic, while neither citric acid, nor potash are so. The problem is attractive, like a puzzle; some day it will be solved, and then we shall wonder why it was not solved before. 102 INFANT-FEEDING. Raw Meat: its Beneficial Effect Experimen- tally Proved. Bichet and Hericourt announced, at the meeting of the Paris Societe de Biologie, June 2d, that they inocu- lated a number of dogs with tuberculosis more than six Fig. 19. Fig. 20. months ago. One-third were fed with ordinary food, and all died in three or four weeks; another set with cooked meat, with about the same results, while the third group was fed exclusively with the raw meat, and all have sur- vived to date and are in good health. infant-feeding. 103 Raw Muscle- juice Possesses Antitoxic Properties. A. Sicarcl 25 says the effect of "zomotherapy" — as Eichet calls his experiments with 328 dogs inoculated with tuberculosis and then fed on raw meat — indicates that the raw muscle-juice has a specific antitoxic power in regard to the tubercle bacillus. The dogs survived, on an average, 300 days, and some for two and a half years, while the control animals all readily succumbed. Sicard discusses the various theories advanced to explain these facts, and suggests that it would be interesting to determine whether other food-elements (codliver-oil, for instance), administered to dogs and guinea-pigs in suffi- cient amounts, would have an inhibiting action on the evolution of experimental bacillosis; also whether forced ingestion of raw or dried meat would transform the cel- lular or humoral medium in animals and render them refractory to infection. Infant-feeding. 2 6 It is impossible to go over the broad domain of arti- ficial feeding in the time usually allotted to a discussion and do justice to all the interesting papers presented. Let me, therefore, give you in brief what would be my personal views based on clinical experience. My first proposition in hand-feeding is: Secure the best possible cows' milk from a reliable dairy. The hy- gienic condition of the cows' stable should be in accord with modern sanitary laws; so that the principle of steril- ization is applied to everything from the stable, to the cow, to the milker's hands, and to all utensils used in milking and transportation, exactly as given by Professor Bagin- sky in his paper, which I had the honor to read at the 25 Presse Medicale (Paris), June 13th. 26 Discussion on infant-feeding, Academy of Medicine, October 18, 1900, by Louis Fischer, M.D. Archives of Pediatrics, January, 1901. 104 INFANT-FEEDING. meeting of the Section on Diseases of Children at Atlantic City, June, 1900. Summing up, then, asepsis — which is really nothing but absolute cleanliness — should be rigidly enforced. Second Proposition. — Imitate Nature in feeding, using raw milk. In this way we copy from Nature just what she has ordained for woman to feed, for it must be admitted that breast-milk (woman's) is raw milk. It is neither boiled, sterilized, nor pasteurized. When the pre- cautions mentioned in my first proposition are carried out, there is no risk of infection. Do we ever stop to think how many millions of mi- crobes lie dormant in the gastro-intestinal canal ready to reinfect the sterilized milk? My plan is to give pure milk (properly diluted or pure) if the age warrants, and merely warm it immediately before feeding it to the infant — temperature of 100° F. We know that a great many children fed on sterilized milk develop scurvy. The same is true of children fed on boiled milk. The reason is, Rundlett so ably says: "Changes take place not in the albumin, fat, nor sugar, but in the albuminate of iron, phosphorus, and possibly in the fluorin vital changes take place. These albumi- noids are certainly in the milk, derived, as it is, from tis- sues that contain them, and are present in a vitalized form, as proteids." On boiling, the change taking place is simply due to the coagulation of the globulin, or proteid molecule, which splits away from the inorganic molecule and thus renders it, as to the iron and fluorin, unabsorbable, and, as to the phosphatic molecule, unassimilable. This is the change that is so vital, and this only takes place when milk is boiled. It is evident that children require phosphatic and ferric proteids in a living form, which are only contained in raw milk. Cheadle says that phosphate of lime is necessary to INFANT-FEEDING. 105 every tissue; no cell-growth can go on without earthy phosphates; even the lowest form of life — such as fungi and bacteria — cannot grow if deprived of them. These salts of lime and magnesia are especially called for in the development of the bony structures. Avoidance of Scurvy. — Since clinical experience has demonstrated that the prolonged use of sterilized and boiled milk will produce scurvy, and that improvement is immediately noted when raw milk is given or raw muscle-juice (beef-juice) or raw white of egg, added to fresh fruit-juices, does it not seem more plausible to com- mence feeding at once with raw milk rather than after scurvy or rickets is developed? There is a certain deadness, or, to put it differently, absence of freshness, in milk that has been boiled or ster- ilized, which causes disease in the infant just as the ab- sence of fresh meats and green vegetables is known to cause scurvy in the adult. GENEEAL EULES FOE FEEDING INFANTS. Each child is a law unto itself, and its individual wants must be studied. One child will gain on the same mixture on which another will lose weight. The proof of the proper assimilation of food in any and every child will be the following: — The infant must appear satisfied after taking its bottle. There should be no vomiting nor severe colicky pains. The bowels must move (unaided) at least once or twice in twenty-four hours. The stools should be yellow- ish white and medium soft. The infant should sleep from four to eight hours at one time during the night. The weight must be taken regularly once a week. If an infant thrives it should gain at least from 6 to 8 ounces every week. When the child's weight shows no increase, then study the reason, and by all means change the food; give more substantial food. 10G INFANT-FEEDING. SUBSTITUTE FOE MILK IN DISEASES OF STOMACH AND INTESTINES. "When milk disagrees and the infant's stomach will not tolerate the same, and vomiting is provoked, or when gastro-intestinal trouble arises, then milk must be stopped. At such times I have seen very good results follow the use of almond-milk (see "Dietary"). Dextrinization is successful in children having sub- normal gastric digestion. The author does not advise the dextrinization of food for healthy children, but only in feeble, ill-nourished, and weakened conditions. CHAPTEK XVI. Cows' Milk. Hammersten 27 gives Konig's analysis of milk in a tlionsancl parts as follows: — Water 874.2 Solids 125.8 Fat 36.5 Sugar 48.1 Salt 7.1 Proteid (casein, 28.8; albumin, 5.3) 34.1 Prof. A. Baginsky 28 gives the following analysis of cows' milk, made at the Kaiser and Kaiserin Friedrich Hospital, Berlin: — Water 87.60 Solids 12.38 In one hundred parts. The solids consist of: — Casein and albumin 3.65 Butter 3.11 Milk-sugar 4.54 Inorganic salts 1-08 Besides large amounts of potassium and potassium salts and small quantities of iron. COMPOSITION, VARIATION, AND PRODUCTION. Milk of all animals, roughly speaking, is composed of the same ingredients, but an analysis of milk is apt to be very misleading, as it does not show the physical 27 "Physiological Chemistry." 28 "Diseases of Children," 1899, page 32. (107) 108 INFANT-FEEDING. condition of the milk, which is the important thing to know from the physician's standpoint. The general ingredients of milk are fat, sugar, albu- min, casein, mucin, salts, and water. These ingredients vary greatly in quantity from day to day and from milk- Fig. 21. — Cows' Milk, showing Fat-globules. Magnified 330 Diameters. ing to milking. An average analysis of woman's milk does not show what an infant is getting, by any means, for the composition of the milk depends on the food and health of the mother and the frequency of nursing. It seems to be pretty well settled that the fat in woman's milk usually varies between 3 and 5 per cent., the sugar between 4 and 8 per cent., proteids (albumin COWS' MILK. 109 and casein) between 1 and 2 per cent., and the ash be- tween 0.2 and 0.4 per cent., the water being about 88 per cent. Wide extremes are met with; so it is useless to think of woman's milk as of a certain composition. Cows' milk, which is the only milk worth consider- ing in connection with artificial infant-feeding, shows great variation in composition, just as does woman's milk. There is no such thing as average cows' milk. It may be that the mixed milk of a particular herd of cows will run uniform in composition for a long time, but this is because the variations in the milk of individual cows offset each other. A difference of 25 per cent, in the amount of fat in night and morning milk has been no- ticed in the milk of some cows. This is why "one cow's milk" should not be used. Mixed milk of different herds of cows will vary between 3 and 5 per cent, fat, 4 and 5 per cent, sugar, 3 and 4 1 / 2 per cent, casein and albu- min, while the ash runs about 0.7 per cent, and the water about 88 per cent., all depending on the breed of cows and their food. Some breeds give large quantities of milk poor in solids, while others give smaller quantities of milk rich in solids. As a general rule, the shorter the interval between milkings, the richer the milk is in solids. Dry food in- creases, and succulent decreases the quantity of solids in the milk. Slight febrile conditions increase the quantity of fat and albumin; depression reduces fat and albumin. Casein, sugar, and ash are the least variable ingredients. The composition of the fat of milk and the size of the fat-globules vary with the period of lactation, the breed of cows, and the kind of food used. Linseedmeal is said to make a soft, oily fat, while cottonseedmeal and some other foods make a hard fat. Small, hard fat-glob- ules are noticeable when the animal becomes pregnant. The practical problem before the physician in bottle- feeding is to prepare a food that approximates mothers' milk in composition and physical properties. To get good 110 INFANT-FEEDING. results good cows' milk must be used, and the physician should know that this can be had anywhere if strict clean- liness is observed by the milkman. Aside from the difference in composition between cows' milk and woman's milk, cows' milk often contains lactic acid and other products of bacterial growth, which may cause digestive disturbance. The lactic acid is the result of the growth of the lactic bacteria that are always found in milk and which get into the milk from the dirt in the stable. Good milk can be had by keeping the cows clean and wiping the udders with a damp cloth just before milking. The first three or four jets from each teat should be thrown away, as they are always infected, and then the milking should be continued into a clean pail. The milk should then be immediately cooled to below 45° F., at which temperature there is little or no growth of bac- teria. Unless this is done the bacteria that always get into the milk, no matter how much care is exercised, will grow rapidly, and, after they have had a start, all the care possible will not repair the damage. Milk produced as described has been known to keep in good condition in summer in a refrigerator for three weeks and it is not at all unusual to buy bottled milk in New York that is forty-eight hours old that will not redden litmus-paper. Cows' Food. — The natural food, fresh grass, is the best; next to this hay is the best. The greater the pro- portion of nitrogen in the food, the greater is the yield of milk, the proportion of fat being especially high. Feeding cows with brewers' grain depreciates the quality by lowering the total solids of the milk. Such feeding is illegal in a great many States, particularly Wisconsin. Beets, carrots, and swedes increase the proportion of milk- sugar. Average Percentage of Fat. — The average percentage of fat found is 4 per cent. The Health Department does not condemn milk having more than 3 per cent, of fat. TUBERCULIN REACTION IN COWS. Ill The uniformity of milk, particularly in New York City, is certainly due to the extreme care and vigilance of the Board of Health of our city. It is not surprising that milk is so frequently adulterated when it is possible to add about 20 per cent, of water or 30 per cent, of skim- milk to milk of average quality without the resulting mixture falling below the present requirements. Tuberculin Reaction in Cows. Conclusions as to the tuberculin test, in the Bulletin of the Massachusetts Agricultural College: — 1. Tuberculin furnishes a very delicate and reliable test, and is the only means by which tuberculosis can be stamped out. 2. A certain number of sound cows will show the tuberculin reaction. 3. A certain number of tuberculous cows will not show the tuberculin reaction. The Cattle Commissioners of Massachusetts had, at Brighton, on February 15, 1895, 40 cattle which they had subjected to the tuberculin test and condemned as tuberculous. The figures of the tuberculin test were carefully reviewed at the office of the commission in Dorchester, and it was decided that 13 of the lot should be killed on that day. There w T ere present Commissioner Herrick and Dr. Lyman, secretary of the commission ; Dr. Burr, inspector for the city of Boston; and Dr. Way, acting in behalf of the owners. At the last moment it was discovered that 3 of the cows had not been appraised and 10 only were killed. Two of the 10 were undoubtedly tuberculous. Four were pronounced to be so by Commissioner Herrick and Dr. Lyman, but declared not to be so by Dr. Way. Their organs were, therefore, sent to Professor Whitney, of Harvard College, for microscopical examination. In 1 of these 4 cows an abscess was found in which was a short 112 INFANT-FEEDING. nail which had apparently caused it. By the most care- ful examination the commissioners could find no signs of tuberculosis in the 4 remaining cows, and they were accordingly dressed and sold for beef. 29 Causes of Tuberculous Diseases in Children. Dr. J. Walter Carr 30 has made investigations as to the starting-point of tuberculous disease in children; he made post-mortem examinations in 120 cases of children who died at the Victoria Hospital, Chelsea, Eng., of vari- ous forms of tuberculosis. He concluded that in two- thirds of the cases the disease began in the thorax and evidently was not due to tuberculous milk (that is, in- fection from the food) and that milk is by no means a frequent channel of infection as compared with infection by the lungs. It is often asserted that tuberculous milk causes the greater part of deaths in children; even sum- mer diarrhoea, cerebral meningitis, peritonitis, "consump- tion of the bowels," etc., are laid to the door of tubercu- lous cows. The fallacy is that consumption (tuberculosis) in children is a generalized condition; in the adult, a localized condition. The mesenteric glands are often affected in children, but careful examination shows that the starting-place was in the thorax. The point is, not what organs are affected at death, but in what organ the disease begins. Dr. Carr says that bacilli are omni- present, and it is impossible to keep a child from contact with them. The great points in the prevention of tuber- culosis in children are the maintaining of perfect health and avoiding respiratory and gastro-intestinal catarrh, and keeping the mucous membrane healthy. Yellowish Milk. Before and after calving milk is yellowish, due to the presence of small, yellow bodies. Such milk is called Spy, Worcester, Mass. Lancet, May 12, 1894. FROZEN AND SOUR MILK. 113 colostrum, and in the case of cows is unfit for human consumption. Pus-cells rather larger than the red blood-corpuscles, granulated, and with a core or irregular contour, are found, as are blood-corpuscles, in the milk of sick cows. They are prevented, as Soxhlet has pointed out, from coalescing into an oily film by the condition of the albu- min, which isolates the fat-corpuscles in its meshes. Frozen Milk. Partial freezing of milk produces a concentration of the solids in the part remaining liquid, while the part frozen is deficient in them. In winter, when milk has undergone a partial freezing, great care should be taken to allow it to thaw and then to thoroughly mix the same before allowing it to be sold. Sour Milk. "When milk stands for some time, fermentative changes due to a micro-organism — usually bacillus acidi ladici — take place. This decomposes the milk-sugar, resulting in the production of lactic acid, which eventually causes the milk to become sour. The change is very largely depend- ent upon the time the milk has been allowed to stand, and more particularly upon the temperature of the place in which it is kept. When the fermentative change has resulted in the production of about 0.4 per cent, of lactic acid, the milk can be distinctly recognized, by the taste, to be sour. When the acidity reaches 0.6 per cent, the milk curdles, and it spontaneously separates into a solid, known as curd, which consists of the fatty and proteid constituents of the milk, and a clear liquid known as whey, which consists essentially of a solution of milk-sugar and mineral salts. This same change is brought about artificially when we add rennet. 114 infant-feeding. Koumiss. This is a preparation of mares' or asses' milk in a partly fermented condition, largely used in Russia. It is prepared as follows: The milk is allowed to cool, and is then deprived of a part of its cream ; a little yeast is then added. This sets up a slow fermentation, the milk-sugar being converted into alcohol and lactic acid. During the fermentation the milk is subjected to frequent agitation, the object of which is to maintain in suspension the casein, which has a tendency to separate during the fer- mentation. Koumiss (called Kumyss) is prepared in this country from cows' milk. The chief manufacturer is Dr. E. P. Brush, of Mt. Vernon, ~N. Y. Another preparation which I have used is known as zoolak and is made by Dr. Dadirrian. GlAOTTRDI. Giaourdi, a food similar to junket and very highly nutritious, has been introduced by Dr. A. Rose, of New York City. It is largely used in Greece, and is adapted for subnormal digestion. The author some time ago used this food and noted good results in a child suffering with marked leucocytosis following pneumonia. It is also adapted for the convalescent period, when restorative foods are indicated. CHAPTER XVII. Buttermilk Feeding. A very elaborate paper on the subject of buttermilk feeding, by Dr. Teixeira de Mattos, of Rotterdam, has re- cently appeared. 31 He cites de Jager, who published a paper 32 recommending this form of feeding; Karger 33 ; Houwing 34 ; and private and public reports of Schloss- mann, Heubner, Soltmann, Finkelstein, de Mattos, and others. While practically unknown one year ago, it is now pushing its way forward. In Holland this treatment is very popular. Buttermilk feeding of children is by no means new, having been used in 1790 by P. Campert (cited by Biedert). Very little appears in literature about this article of diet until in IS 65 Dr. Ballot, of Holland, again revived and recommended it. To Prepare the Food: Take 1 quart (liter) of buttermilk; add 1 even tablespoonful of rice, wheat, or other flour desired (about 10 to 12 grammes) ; heat the mixture over a small gas fire, with constant stirring, until it has boiled up three different times (requiring about twenty-five minutes) ; then add 2 or 3 tablespoonfuls (about 70 to 90 grammes) of cane-sugar or beet- sugar. It is better to use new enameled ware or agate ware for preparing this food. The food as above prepared assumes a yellowish color. 31 Jalirbuch fur Kinderheilkunde, January, 1902. 32 Nederlandsch Tydschrif t voor Geneeskundigebladen, October, 1895. 33 "Die Verdauung und assimilation des Gesunden und Kranken Sauglings, nebst einer rationellen methode zur Senglingsernahrung," Berlin, 1898. 3 * Centralblatt fur Gyniikologie, 51, 190. (115) 116 INFANT-FEEDING. It is necessary to have large corks for the bottle or the food coagulates and gets lumpy, in which event it would re- quire occasional shaking to bring the thickened portion to the proper consistency. De Mattos reports a series of cases in which butter- milk was used. The bulk of these cases were ansemic, atrophic cases requiring restorative treatment. In all cases reported the weight was increased and dyspeptic symptoms, when present, rapidly disappeared. The increase in weight noted by de Mattos was from 500 to TOO grammes weekly in debilitated children, and Schlossmann reports as much as 700 grammes' increase in six days. Graanboom, in his recent book on "Diseases of the Digestive Tract in Children" (1901), states that he also is very much impressed with the value of buttermilk as an infant-food. De Mattos states that children so fed for a period of six to eight months show signs of rickets or late dentition, although they look well and appear to be well nourished. Whether or not other methods are worse he does not state. Lactic acid was never found in the urine of infants fed either with lactic acid or its salts. This series of experiments was made by de Mattos, and the results were corroborated by Houwing. The amount of lactic acid present in buttermilk has been carefully studied. Robertson, a chemist, found it to be: — Minimum 0.09 per cent. Maximum 0.45 per cent. De Jager believes that good buttermilk does not con- tain more than 0.5 per cent, of free lactic acid. 35 These are, however, not absolute and positive data, but really individual hypotheses. 35 Nederlandsch Tydschrift voor Geneeskundigebladen, 1899, i, S. 945. BUTTERMILK-FEEDING. 117 Contrary to the ideas of Munk, Uflelmann, and Ewald (who fear the use of food containing lactic acid), de Mat- tos has found that chronic enteritis and gastric complaints soon improve when an exclusive buttermilk feeding is resorted to. Hayem and Lesage regard lactic acid as en- tirely innocuous for nurslings. According to the above- named investigators, lactic acid is not toxic for infants. They gave experimentally 15 to 20 grains in divided doses, mixed with sugar, without seeing any detrimental results. Jaworski 36 found no trace of lactic acid in an infant's stomach one hour after administering it. Biel maintains that lactic acid improves digestion, while Duclaux 37 states that lactic acid is a valuable as- tringent. Heubner 38 found lactic acid in the stomach of two healthy infants (to the extent of 0.16 to 0.2 per cent.). Marfan (quoting Zotow) maintains that, when lactic acid is found in the stomach of infants, it is always a pathological factor. Buttermilk in its crude (raw) state is certainly an- tagonistic to other micro-organisms. This is due to the presence of lactic-acid bacilli. Raw cows' milk possesses bactericidal properties, but buttermilk is much more bac- tericidal. The latter, sterilized with the aid of steam, showed virulent typhoid bacilli nine days after being in- oculated with the same. In non-sterilized buttermilk {raw state) virulent typhoid bacilli lost their virulence after two days, and when put into the brooding oven lost their virulence after twenty-four hours. The bacillus lacticus of Pasteur and Hueppe seems to be identical with the bacillus lactis aerogenes of Escherich, 39 which is found in the upper part of the small intestine. Jaworski found that pepsin is more readily secreted when lactic acid is given internally. De Mattos states 36 Deutsches Archiv f iir klinische Medicin, Bd. xxxvii, i. 37 "Maladies de PEnfance," tome ii, p. 606. 38 "Jalirbuch fur Kinderheilkunde," 1891. 89 "Die Darmbacterien des Sauglings," Stuttgart, 1SS6. 118 INFANT-FEEDING. that he has never met with a case of Barlow's disease among infants fed with buttermilk. Disagreeable symptoms are frequently encountered for the first few weeks while giving buttermilk. Such are frequent vomiting and diarrhoea. These are not contra-indications for feeding, and, notwithstanding the presence of the above-named symptoms, the feeding should be continued. If, however, the symptoms are very severe, then the administration of astringents — such as bismuth, argent nitrate, tannalbin, or ichthalbin — may be required for temporary relief. An important point is that in this form of infant- feeding the large, thick, cheesy curds so commonly met with in dyspepsia and diarrhoeas in feeding with cows' milk are never seen. Children thus fed seem to with- stand the infectious diseases very well. A point worth noting is that when a child is more accustomed to butter- milk feeding the change to sweet milk will cause diar- rhoea. When we find that the weight is not increased and we desire to change to sweet milk, the latter should be gradually adoled to the buttermilk instead of making a distinct change suddenly. Quality of the Buttermilk. — This is the most impor- tant part of our subject. In securing our food we must be sure that w& are dealing with honest dairymen whose sole object is to deliver what is demanded for weak in- fants. Stale combinations made by the use of left-over centrifuged milk or skim-milk or spoiled milk which cannot be used otherwise should be inquired into and rejected. Good buttermilk can be made from either whole milk or from cream. In Holland buttermilk is made by pas- teurizing cream in Timpe's apparatus and then inoculat- ing and buttering the same with a pure culture of lactic- acid bacillus. In order that raw milk will yield butter- milk a certain percentage of acidity must be present. BUTTERMILK-FEEDING. 119 The usual precautions in milking (so-called modern stable hygiene) must be observed in securing milk to be used in making buttermilk. The milk should be received in sterile vessels and rapidly cooled, and should then be kept in cool cellars or ice-coolers having a low tempera- ture (no higher than 15° or 20° C.) for eighteen to twenty-four hours. It is necessary to stir the milk occa- sionally. Rapidity of souring can be assisted by adding sour milk or by inoculating with a pure culture of lactic- acid bacilli. ]STo definite rule can be laid down as to when buttering takes place; empiric methods must decide this matter. This is due to the size of the vessel used and the influence of seasonal changes, and also the amount of churning it had received. Cows' milk which contains colostrum or which is bitter is not adapted for buttering. Butter should form in small, pin-head-sized particles in thirty to forty-five minutes. It is regarded as a mis- take to have large particles of the size of a pea or larger, and dairymen look upon such buttermilk with suspicion. Buttermilk in general contains about 0.3 to 0.4 per cent, of fat. Escherich states that the fermentation of milk is due to the splitting up of the milk-sugar whereby lactic acid, 0, and C0 2 are formed in the intestine. The following table is instructive in showing the per- centage of acidity present and also the difference in fat: — Specific Gravity. Solids, Percentage. Fat. Acidity According to Soxhlet-Hf.nkel. Sour milk before buttering 1.029 11.40 2.8 18.1 Buttermilk 1.029 9.60 0.5 16.1 There is, therefore, a difference of 2 per cent, in the amount of acidity present in favor of buttermilk. 120 INFANT-FEEDING. An important point is to overcome the lum.ps usually found as coarse coagula in buttermillc. De Mattos advises adding flour — either rice, wheat, or lentil — or even some pro- prietary infant-foods, according to the requirements of the infant. This is merely given to hold the flocculi in finer form and to prevent their coagulation into lumps. Dyspeptic children with subnormal digestive powers should receive a minimal quantity; thus, an even tablespoonful, amount- ing to about 10 grammes, will suffice. Addition of Sugar. — The quantity of sugar to be added must be reckoned empirically; thus, 3 tablespoon- fuls, about 90 grammes, are required to each liter of buttermilk. Rarely do we need more than 100 grammes. Cane-sugar or beet-sugar serves best for sweetening. Sugar cannot be found in the urine nor in the faeces of infants fed on buttermilk to which sugar was added. The results which might be expected from using cane- sugar — such as diarrhoea, fermentation, sour eructations — are totally absent in using buttermilk feeding. Stools. — The average buttermilk-fed infant has no more than one or two stools daily. They are more or less solid in consistency and have an alkaline reaction. It would be incorrect to state that all children fed with buttermilk must have yellow stools. We know that even UfTelmann, in his studies of infant-stools, states that breast-fed infants show great variations from apparent normal stools and still thrive. We also know that bottle- fed infants reared on cows' milk have no definite hind of stool which we could call a standard stool. Still, the buttermilk-fed infant never has the coarse casein particles in the faeces that we see very frequently in the stools of infants fed on cows' milk. The bacteriological examination of the faeces made by inoculating gelatin plates with diluted faeces showed: — 1. Liquefying colonies rendered Loeffler's nutrient gelatin strongly alkaline. Inoculated into bouillon, the BUTTERMILK-FEEDING. 121 latter remained clear, forming a skim on the surface. Milk was not coagulated by these micro-organisms. They formed spores, generated H 2 S, and can therefore be iden- tified as the bacillus butyricus of Hueppe. 2. ISTon-liquefying colonies were inoculated into milk- sugar bouillon and left in the brooding oven eight hours at 37 °C. All tubes so treated were turbid on standing over night; this fact excludes the possibility of its being the bacterium coli. Other properties were found, such as: fermentation in milk-sugar bouillon, no skim forming on the bouillon; indol does not form in peptone solution (bacterium coli would form indol); milk turns sour but slowly; no ]SFH 3 formation. From a study of the above properties we conclude: — ■ 1. Bacterium coli commune must be excluded. 2. Bacterium coli lactici, Hueppe (resp. bacterium lactis aerogenes, Escherich), must be identified. The lactic-acid bacillus, found in boiled as well as raw buttermilk, loses its potency in the intestinal canal in the presence of the bacillus butyricus, Hueppe. The latter germ grows in overwhelming numbers and renders the intestinal contents rapidly alkaline. An interesting point is that, if the buttermilk were originally very sour, the faeces will be very alkaline, show- ing how weak the bacterium acidi lactici is. Feeding. — The writer has seen excellent results from buttermilk feeding in atrophic and marasmic children. As an article of diet during convalescence after pneu- monia and typhoid fever the results were encouraging. Quantity to be Fed. — Buttermilk as above prepared should be fed exactly as would other milk. Four ounces, increased to 5 or 6 ounces, can be fed every 3 hours, or the interval may be prolonged to 3 1 / 2 or 4 hours. It will be necessary to coax the child in beginning with this new form of feeding, owing to the difference in the taste of fresh milk and buttermilk. CHAPTER XVIII. Detection and Addition of Preservatives to Milk. The preservatives most frequently employed are: borax and boric acid, formaldehyde, salicylic acid, and potassium clir ornate. Formaldehyde 40 is the most effective, and, when the same becomes better known, it will supersede all other preservatives. The above chemicals are sold to farmers and dairymen as "milk-preservatives." The table on the following page will show the efficiency of the various milk-preservers, and is taken from T. H. Pearmain and C. G. Moor, on "Milk and Milk-products." Formaldehyde is usually added to milk in the form of a 40-per-cent. solution, commonly called formalin; 2 or 3 drops added to a pint of milk will keep it fresh for three or four days, and the addition of 0.05 per cent, will preserve milk for months. In the trade a much more dilute solution is generally employed, namely: 1 part of formaldehyde to 80 parts of water. Rideal states that a quarter of a pint of such a solution will keep seventeen or eighteen gallons of milk fresh for at least three days, and will not impart any smell or taste to the same. On tasting milk containing formaldehyde a peculiar sensa- tion is noticed at the back of the throat, and when strong hydrochloric acid is added to it (Werner Schmidt process) the casein turns yellow and is less soluble than that of pure milk. Hehner's test is the most reliable. When 40 The- New York Medical Record, as recently as July 21, 1900, contains the following: — "Many milk-dealers in New Jersey have been arrested on the complaint of the State dairy commissioner for adulterating milk, the special adulterant being formaldehyde, added as a preservative." (122) DETECTION AND ADDITION OF PRESERVATIVES. 123 After 11 Days. Lactic Acid, Per Cent. o 1*8 *3° 2 o 02 +3 4-3 02 CM ■ m o © £co o" After 8 Days. Lactic Acid, Per Cent. QO CO o +3 02 43 go 02 1 S - CO CM ■<*l © Is &Bd 02 gco 02° o2 02 SiO o . 02° g 3 . S5 w ■* >t &. 2 3 02 01 02 OI Oi 02 43 o> 02 5.2 72 OI SB 02 -d s 3 43 0> OI SB 02 M 3 o 02 o a S . •« * w 6. < 3 o 02 4^ 0) 02 CB CO SB 02 43 01 S= 02 CO CI (4 3 EH 43 0> o> SB 02 43 CO co |£ 02 OI 0) SB 02 4^ u 5 3 02^ g a Z oi top <1 HI 3" O s 02 SB 02 01 0) SB 02 CB CO 5= 02 OI Oi SB 02 OI OI Sb CO OI 01 SB 02 43 OI OI & 02 43 CD CO SB CO g a IS 5 >> .S fl to 3 43 CO 0) g; 02 02 co 9 02 43 OI Oi & 02 43 CO CB & 02 43 OI CB &: 50 CO CB SB 02 43 a) CO SB 02 Grains of Preservative Used per Gallon of Mile. 43 s CC 04 IC o lO n h-' 0) 1-4 Q, IS O © 43* a co o lO in CC 01 ft to o © 43 s o io - CO CD ft m o © o 01 *Qu-i CO-g 1-^ 43 C CO o in t, lO CM o © 43 c Oi o in ^ CO 01 m o o a CO o 1(5 - tlft m CM o o a a ? up a ' 4J o,2 « fc2 a WB. ft fc.2 ft «o 2 '3 oi o '£ o cq d i o nt>5 'SSod °2c1 s O O 02 '2 cS o ">> o "cS 02 S '5 d o o SI 3 o> cq 124 INFANT-FEEDING. milk, formalin, and sulphuric acid are mixed together a blue coloration is formed. According to Richmond and Bosely, it is best to dilute the milk with equal quantities of water and add sulphuric acid, about 90- to 94-per-cent. strength. When formalin is absent, the milk gives a slight-greenish tinge at the junction of the two liquids, while a violet ring is formed when formaldehyde is pres- ent. This color remains permanent for several days. In the absence of formalin, a brownish-red color is developed after some hours, not at the junction of the two liquids, but lower down in the acid. This cannot be mistaken by anyone who has had any experience with the test for the formaldehyde reaction. It is stated that 1 'part of formalin can he easily detected by means of this test in 200,000 parts of milk, but the blue coloration is not ob- tained with milk containing over 0.5 per cent. Another very sensitive test for the detection of for- malin in cows' milk is the following: If to the distillate from a sample of milk 1 drop of a dilute aqueous solution of phenol is added and the mixture poured upon strong sulphuric acid contained in a test-tube, a bright-crimson color appears in the zone of contact. This color is still readily seen with 1 part of formaldehyde in 200,000 of water. If there is more than 1 part in 100,000 there is seen above the red ring a white, milky zone, while in stronger solutions a copious white or slightly pink, curdy precipitate is obtained. This reaction has an advantage over the one previously referred to, as it is obtained with formaldehyde solutions of all strengths, while the blue color of milk is not obtained with milk containing much formaldehyde. Salicylic acid is not very much in vogue as a milk- preservative. It can easily be detected by Pellet's method : 200 cubic centimetres of the milk are diluted with an equal measure of water, heated to 60° O. and treated with 1 cubic centimetre of acetic acid and an excess of mer- curic nitrate free from mercurous salt. The salicylic acid DETECTION AND ADDITION OF PRESERVATIVES. 125 is extracted from the filtered solution by agitation in ether and recognized by evaporating a little of the ethereal solution to dryness and testing the residue with ferric chloride, which gives a violet color with salicylic acid. Pearmain and Moor, in describing the bacteriology of milk, say that it usually contains a large number of bac- teria derived from the external surroundings of the cow. Where these are unclean, the number may reach three or more millions per cubic centimetre. These can, "for ex- perimental purposes," be completely separated by filtra- tion through Pasteur tubes, the tubes being cleaned at short intervals. A thin, watery serum constitutes the filtrate, the whole of the fat being arrested with the organisms, so that milk cannot therefore be freed from organisms for practical purposes by any known system of filtration. Milk can be curdled by ferments even in the absence of an acid reaction. The most notable fer- ment is rennet, obtained from the stomach of a calf. ITueppe first pointed out that such ferments are conveyed by many different bacteria which precipitate the casein in the presence of a weakly acid, amphoteric, or even neutral solution. The numerous tyrothrix bacilli isolated by Duclaux, the bacillus pyocyaneus, yellow sarcina, and particularly the organisms described by Fliigge, 41 char- acterized by their capacity to peptonize milk, belong to this class. Colin 42 produced the precipitation even by means of bacteria, whose vegetative capacity had been completely abolished with chloroform, thus showing that the fermentative action was due to a substance independ- ent of the metabolic products of the organism. These substances have been isolated by Cohn and others. They are destroyed in most cases at from 65° to 75° C. Some ferments, however, as, for example, that described by Gorini in association with the bacillus prodigiosus, resist 41 Zeitschrift fur Hygiene, xvii, page 272. 42 Centralblatt fiir Bacteriologie, ix, page 653. 126 INFANT-FEEDING. as much as an hour's exposure to 70° or 80° C, and require at least half an hour's exposure to 100° C. (or 212° F.) for their destruction. It is practically inevitable that milk, as delivered from the cow, should contain a number, and usually a very large number, of bacteria. The extent of their presence is, however, affected by many circumstances, of which some are also indications of unwholesomeness or danger. Many of the organisms which are capable of causing disease do so by producing toxic • decomposition- products from the milk. Their vegetative capacity in- creases greatly with rise of temperature, and it is there- fore an essential condition of sanitary milk-production, and especially of a milk designated as suitable for children, that it should be kept at a low temperature during the whole of the interval between being drawn and being con- sumed. Yellow milk is said to be colored by the bacillus syn- xanthus of Schroter, the color being removed by acids and restored by alkalies. Salty milk is stated to occur only in connection with inflammation of the udder. It is to be detected not only by its taste and its high percentage of ash, but by its low percentage of milk-sugar. Its specific gravity is 1.027 to 1.029. According to Klenze, 2.4 per cent, of small deposits of calcium carbonate in the milk-glands may give rise to sandy milk. Curious results have been noted by Scheurlen 43 in experimenting with bacteria in milk. He found that milk can be freed from bacteria by the opera- tion of a centrifugal machine. He also noted that, of the large majority of bacteria contained in milk, three-fourths went into the cream on being centrifugalized, and the rest stayed in the separated milk, and the same result was obtained by merely leaving the milk stand. These results held good not only for the ordinary milk bacteria, but also "Arbeiten a. d. k. Ges. Amt. 3 vii 3 1891. THE BREED OF A COW. 127 for anthrax, typhoid, and cholera. The tubercle bacillus only remained to a small extent in either the milk or the cream, and the large majority was ejected under the cen- trifugal influence. The biological commission on milk- supply held under the auspices of the British Medical Journal for 1895, reported the following: 1. That all milking be carried on in the open air, the animal and operators standing on a material which is capable of being thoroughly washed, such as a floor of concrete or cement. Such a floor could be easily laid down in any convenient place which can be found. The site chosen should be re- moved from inhabited parts as far as possible, and should be provided with a plentiful water-supply. Only in this way does it seem possible to avoid the initial contamina- tion with the colon bacillus. 2. That greater care should be expended on the personal cleanliness of the cows; the only too familiar picture of the animal's hindquarters, flanks, and side being thickly plastered with mud and faeces is one that should occur no longer. It would not; be difficult to carry out this change. Indeed, in the better managed of our large dairy companies' farms such a con- dition no longer prevails, but in the smaller farms it is but too frequently met with. 3. That the hands of the milker be thoroughly washed before the operation of milking is commenced, and that after once being washed they be not again employed in handling the cow, other- wise than in the necessary operation of milking. Any such handling should be succeeded by another washing in fresh water before again commencing to milk. 4. That all milk-venders' shops should be kept far cleaner than is often the case at present; that all milk-retailing shops should be compelled to provide proper storage accommo- dation, and that the counters, etc., should be tiled. The Breed of a Cow. Some breeds yield quantity, others quality. Tlolsteins produce the most milk; Alderneys and Jerseys yield the 128 INFANT-FEEDING. most fat ; shorthorns give the most casein and sugar. The average capacity of a cows' udder is about 5 pints, and the annual yield of milk is about 600 gallons. Time and Stage of Milking. Cows are usually milked twice a day, the morning milk usually being larger in quantity and poorer in qual- ity. The milk which is first drawn is known as the fore- milk, and contains very much less fat than that last drawn, known as the strippings. This is due to a partial cream- ing taking place in the udders. Dishonest dealers have often taken advantage of this fact in adulteration cases to have the cows partially milked in the presence of ignorant witnesses, the resulting milk consisting largely of the fore- milk. Age of Cows. Young cows give less milk, while cows from four to seven years old give the richest milk, and less milk is given with the first calf. They give the largest yield, ac- cording to Fleishmann, after the fifth until the seventh calf; after the fourteenth calf they yield, as a rule, no more milk. The poorest milk is yielded during the spring and early summer; the richest during the autumn and early winter. If cows are worried or driven about, the quality and quantity of the milk are reduced. If they are kept warm and well fed, both quantity and quality are naturally increased. Effect of Alkalies on Milk. By running milk through a centrifugal machine a product known as "separator slime" is produced, which is analogous to mucin. A decided difference in viscosity is noticed between milk before and after running it through a centrifugal machine. This "separator slime" swells up and forms a viscid jelly with lime-water or alkalies. Milk to which alkali is added is decidedly more viscous than ALBUMINOIDS IN COWS* MILK. 129 milk that is slightly acid, and is so undoubtedly because of the action of the alkali on the mucin of the milk. CuKDLING OF MlLK AND DlLUENTS. Milk of all animals may be separated into two classes. Those that form a soft curd with rennet and those that form a hard curd with rennet. Woman's 'milk is in the first class and cows' milk in the second. The conditions favorable for the formation of hard curds of cows' milk are body-heat and the presence of rennet and lactic or other acid. The rennet forms a clot of the milk, the heat causes the lactic bacteria to grow in the curd, and the acid causes the curd to shrink and become leathery. Adding alkalies to the milk neutralizes the acid, but the bacteria will keep making more lactic acid as long as any sugar is present. Diluting milk with water does not prevent tough curds forming, but diluting with gruels does prevent the contraction of the curds. This has been proved beyond dispute, both experimentally and clinically. Albuminoids in Cows' Milk. That there are differences in the amounts of the albu- minoids occurring in human milk is proved by the fact that, while Professor Leeds found a variation of 0.85 to 4.86, Professor Meiggs asserts that there was but 1 per cent. Konig, an earlier analyst, makes the variation from 0.85 to 4.86. Some of these results give as high a per- centage of albuminoids in woman's milk as we find in cows' milk, and I have no doubt in my own mind that the time and habit of extracting the milk has a deal to do with the amount of occurring albuminoids. In other words, when milk is extracted every two hours or less, it cannot contain as much of the cell-material as milk from the same source extracted at intervals of twelve hours. This latter is riper and it is the non-uniformity of the 130 INFANT-FEEDING. tissue which causes all the difference in the different oc- curring albuminoids. We know that during the incuba- tion of eggs casein is developed from egg-albumin. This illustrates the ripening of albumin. Furthermore, take an egg just laid by the hen, and boil it, and you will find immature albumin in it; that is, after boiling, instead of being thick and firm, like an older egg, much of it is milky. If boiled a few hours later, all the albumin will coagulate perfectly, because it has had time to ripen. There is no doubt that the albuminoids in milk from healthy animals are all cell-transformations, not an exu- date, as are undoubtedly the fats and salts, because these latter we can influence by the food very plainly, but in health the albuminoids are constant without regard to food, while during menstruation, pregnancy, and other conditions, notably febrile disturbances, we find the fats and salts not materially affected, but the albuminoids de- creased, increased, or totally changed, as in the case of colostrum. The casein, besides being riper in cows' milk, by reason of its stronger growth, is intended by Nature to coagulate into a hard mass, because it is the product of a cud-chewer for the nourishment of a cud-chewer, and the reason why it does not always coagulate in the infant's stomach as it does in that of the calf is that the latter animal's stomach secretes a principle called chy- mosin; this is the principle that curdles cows' milk, and it operates either in an acid or an alkaline medium. Pep- sin will not coagulate milk, and hence the hard coagulum of cows' milk that sometimes forms in the infant's stom- ach is due to acidity of that organ, and this acidity is not always the fault of the stomach, but of the milk itself. The variations in the chemistry of the albuminoids found in cows' milk would not be surprising to anyone if he would examine into the condition of some of its mam- mary sources. Thus it will often be found, on dissecting a cow's udder, which I always do when making an au- topsy on a cow, that there are old cicatrices, one or more ALBUMINOIDS IN" COWS' MILK. 131 quarters of the udder intensely inflamed, sometimes a mammiferous duct clogged with a calculus or a clot of fibrin. Besides these pathological conditions, the mam- mary gland is subject to benign and malign infiltrations, bacillary tubercular deposits, and eruptive diseases of the skin involving the gland and ducts. Therefore, that fibrin, serum, and albumin, in various forms, are found in the cows' milk is not surprising, and it can safely be assumed that any variation in the albuminoids from the normal casein can be ascribed to sickness on the part of the animal. "We next come to the salts contained in milk, and it is remarkable how few analyses have been made to deter- mine the salts or minerals that are contained in this fluid. Heidlen's analysis, copied everywhere, seems to be the only exhaustive one of the salines in cows' milk made during the past century. It seems to me in this case, too, that it is time for the chemist to teach us something more. There probably never was a time, in our era, at least, when milk was attracting so much attention as now, and still all our chemists are content with the total solids, fats, albuminoids and sugar — just what the butter-makers and cheese-makers want to know. From this much-quoted analysis of cows'-milk salts we learn that milk contains in various proportions the phosphates of lime, magnesia, and iron; the chlorides of potassium, sodium, and iron; and free soda. Robin gets from human milk, in addition to the foregoing, carbonate of lime and soda, phosphate of soda, sulphate of soda, and potash. We have no means of knowing how constant is the occurrence of any of these salts in milk or under what conditions they are modified; we do know, however, from the experiments of Fehling, that many of the drugs administered to the milking fe- male are excreted in the milk. Therefore, we can safely assume that the saline constituents occurring in. milk are influenced both by the health and food of the animal. That the phosphates are craved for oy the milking cow is 132 INFANT-FEEDING. evidenced by the habit of chewing old bones and the like, and that there is a lack of this element of food is not to he wondered at when we see herds of milking cows pas- tured on old, worn-out lands; the practical farmer knows that exhausted pasture-lands need, more than anything else for their rejuvenescence, the phosphates, and we know that in our nutrition we need them also. The land on which a cow is pastured will indicate pretty fairly what we may expect to find in her milk as salts. We have all noticed the excessive growth of sorrel on ex- hausted land. Can it then be a subject of wonder that some kind of a vegetable acid should be found in the milk of animals that are obliged to include this variety of food in their summer-rations and sour ensilage or spoiled brew- ery grains in their winter-feed? Theodore Hankel's dis- covery of citric acid in cows' milk to the amount of 0.9 and 1.1 grammes per litre is just what might be expected. Sugar, I think, in milk has always been overestimated as to its nutritive value, because we know that carnivo- rous animals do not secrete sugar to any appreciable ex- tent, according to chemists. When we see a small slut nursing seven or eight puppies and keeping them all fat, and in a thriving condition, we can easily imagine that sugar is not a necessary element of food, for the canines excrete no sugar in their milk. We see that the gross re- sult of condensed-milk feeding with an excess of sugar is harmful. Brush maintains that pure cane-sugar is the ideal addition to cows' milk. Prof. L. B. Arnold, an authority on dairy matters, says that when milk will not properly nourish an infant it is not the cows' milk that is at fault, but that it is either a pathological condition of the cow or improper food or care, or the conditions through which the milk has passed on its way from the cow to the infant. The average temperature of a cow is 102 1 / 2 ° F. (Brush). "This is certainly a peculiarity of the cow. An- other peculiarity is the constant employment of her gen- ALBUMINOIDS IN COWS' MILK. 133 erative functions : she is always milking or pregnant, and both the uterus and the mammary glands are employed almost constantly at the same time. Her nervous system is more subject to severe shocks, and she is a delicate creature. As regards the average income from a cow, it is about $20.00 a year to the producer. This is about 7 cents a day, from which the dairyman has to buy food and pay for labor. In order to make a profit the dairy- man must utilize every drop of milk, whether the animal giving it be sick or well. It is, therefore, very common to find that all the cheap foods, such as brewery grains, distillery slops, and the refuse from starch-factories enter largely into the food from which our babies' supply of milk is produced. Brush maintains that personal inspec- tions of small dairies near New York City showed the sole article of diet to be swill. One of the means employed for removing the stable odors of milk is adding nitrate of potash, commonly known as "saltpeter." With this drug a substance resembling nitroglycerin is formed. It is strange that the toxic effects of nitroglycerin are sim- ilar to those of tyrotoxicon. Brush believes that the ideal dairy for supplying in- fant-food should be composed entirely of spayed cows, and thus one constant source of nervous function of dis- turbance would be eliminated. He believes that these animals are much more quiet in disposition, they give a more constant and uniform supply of milk, and seem to enjoy a more even degree of health than the cow who is occasionally bulling and becoming pregnant when giving milk. The author has certainly had very good results with Brush's milk, and, although it is somewhat expensive, he has found it well adapted for the home-modification of infants' food. CHAPTER XIX. Cream. When food contains too little fat, or its equivalent (cream), we have fat-starvation, which is soon manifested by symptoms of rickets. One of the earliest symptoms of rickets is constipation, showing deficient muscular tone: a distinct atony of the bowel. This can be remedied by the addition of fat or cream to the food. Some children are benefited by giving them codliver-oil, butter, or olive-oil. Some authors advise giv- ing fried bacon to very young children; thus it is plain that each one desires to remedy the deficiency of fat in his own manner. In buying cream from small milk-stores one can make a rough guess at the proportion of fat in cream by its thickness. A 50-per-cent. cream at the ordinary tem- perature of the room runs from a jug slowly and in a thick stream, almost like thick mucilage, whereas a 16- per-cent. cream runs almost as freely as milk. This is, however, a crude way of estimating the difference be- tween poor and rich cream. It is a very important point to know exactly what percentage of cream we are using, for such mixtures like Biedert's, in which 1 ounce of cream is mixed with 3 ounces of water, may agree very well when we use a 16- or 20-per-cent. cream, but might be disastrous if we use a cream containing 40 per cent, of fat. Such infants would not tolerate this rich cream, and might have troublesome vomiting. CREAM FOR HOME-MODIFICATION. Ordinary Cream.- — This is made by setting milk at night and skimming it in the morning; it is called grav- ity, or skimmed, cream, and contains 16 per cent, of fat. (134) CREAM. 135 Twelve-per-cent. Cream. — Obtained in the city by using equal parts of ordinary (20-per-cent.) centrifu- gal cream and plain milk. In the country we must use 2 parts of ordinary skimmed, or gravity, cream (16 per cent.) with 1 part of plain milk, or by taking the top layer of milk, after it has stood five or six hours, by means of siphoning. EigM-per-cent. cream is obtained in the city by dilut- ing 1 part of centrifugal (20-per-cent.) cream with 3 parts of plain milk; in the country, by using 1 part of gravity cream and 2 parts of plain milk, or by using the top layer of milk that has been standing five or six hours, siphoning it off. Top-milk is obtained directly from fresh milk by the so-called "gravity process." Cream contains a great deal of fat, usually three-fifths of cream is fat; this floats on the surface of the watery milk. If a quart bottle of the average city milk is put into ice-water or upon ice in the refrigerator, and removed after four or five hours, we can skim off from the top about 10 ounces of an 8-per-cent. cream; after six hours about 6 ounces of 12-per-cent. cream. This I shall speak of as top-milk. Frequently, instead of skimming the cream, the lower portion is si- phoned off, leaving the cream in the glass bottle. When cream is removed by a centrifugal machine, it is known as centrifugal cream. It can be separated much more quickly than so-called gravity cream, which must rise naturally and slowly from milk that is allowed to stand. HOW TO PKOCUKE CKEAM. Set aside the ordinary quart bottle of milk on the ice for several hours (from six to eight hours) to allow the cream to rise. After the cream has risen draw the milk from the bottom of the bottle; this can be accomplished by means of a siphon. To make the siphon get a piece of glass tubing 21 inches in length and a quarter of an inch in calibre. This 136 INFANT-FEEDING. can be procured in any drug-store. German glass is less liable to crack than American glass. If the glass tubing is longer than 21 inches make a small scratch in it, after measuring off 21 inches, with a three-cornered file; then grasp the glass tubing between the fingers and opposing thumbs of both hands, having the thumb-nails touching each other on the side of the glass just opposite to the scratch. On attempting to bend the glass tube it will break smoothly across, and if there are any sharp edges they can be smoothed by rubbing them down with the file. To bend the glass tube to the V shape, hold it in the flame of an ordinary gas-jet or alcohol-lamp for a few moments, twirling the glass rod until it softens suf- ficiently to allow it to be bent to the required angle. The tube should be warmed gradually at first, and then put right into the flame. It is better in bending the glass to make one arm of the siphon a few inches longer than the other. In using the siphon hold it with the angle down, fill it with water, and close the long arm with the tip of the finger; then, keeping the finger applied to the long end, turn the siphon with the angle up, and introduce the short arm into the bottle of milk, letting it rest upon the bot- tom. On removing the finger, the milk will flow through the tube, and continue to do so until the bottle is empty. It is, therefore, necessary to watch the layer of cream, so that the siphon can be lifted out of the bottle just before the cream reaches it. There will thus remain in the milk- bottle all of the cream and a small portion of the milk, the latter depending upon the expertness of the person using the siphon. TO PASTEURIZE THE CKEAM. Take a clear glass bottle having a neck not very wide ; fit into the same a perforated cork with a chemical ther- mometer registering up to 212° F. The bulb of the ther- MODIFICATION OF MILK. 137 mometer should come within half an inch of the bottom of the bottle. The cream is put into the bottle, and the cork carrying the thermometer is inserted; the bottle is then placed in a pot containing a couple of inches of warm water and allowed to heat on the stove. The ther- mometer should be watched until it reaches 160, taking care that it does not go above 170. When the thermom- eter has reached this point, set the pot back on the stove where it will cool off, and allow it to remain there for twenty minutes. At the end of this time substitute a plug of absorbent cotton for the cork containing the ther- mometer. Great care must be taken to keep the absorbent cotton dry. Cream thus prepared is pasteurized, and will keep sweet and fresh for twenty-four hours without being kept on ice, and all that is necessary in removing a por- tion from the bottle is to be sure that the cotton plug does not become moist, or, if it should, to replace it with a dry piece at once. TO CLEAN THE GLASS SIPHON. It is advised to fill it with water immediately after using it, and the ordinary tube-brush having eighteen inches of wire added to it will permit thorough cleansing. Nothing, however, will be found as good as thorough boiling in plain water to which a pinch of soda has been added. Modification of Milk. It has been shown previously that the percentages of fat in woman's and in cows' milk are about the same, that the quantity of sugar is rather lower in cows' milk, and that the quantity of casein and albumin is greater in cows' milk, as is also that of the ash. Experience has shown that cows' milk must be diluted before it can safely be fed to infants. Simply diluting the milk reduces the percentages of fat and sugar too much; so the practice of adding cream and sugar has arisen, but the processes that 138 INFANT-FEEDTNO. liave been advocated for obtaining the desired additional quantities of fat and sugar have been too complicated for general nse. The top 9 ounces of a quart of milk on which the cream has risen will be about three times as rich in fat as the whole milk, the top 15 or 16 ounces will be about twice as rich as the whole milk, while the other ingredi- ents remain about the same as in whole milk. For babies under 3 months of age the top 9 ounces of a quart of milk on which the cream has risen should be diluted from 3 to 10 times and 1 part of sugar added to 25 parts of food. For babies 3 to 6 months old the top 16 ounces of a quart of milk on which the cream has risen should be diluted 2 or 3 times and 1 part of sugar added to 25 or 30 parts of food.. For babies 6 to 9 months old the top 20 ounces of a quart of milk on which the cream has risen should be diluted 1 / 2 to 1 time and 1 part of sugar added to 50 parts of food. An even tablespoonful of granulated sugar equals 1 / 2 ounce. By following this method the infant commences on weak mixtures that show about the same composition and variations as mothers' milk and gradually takes food richer in casein until plain milk is reached. The diluents used are water, gruels, or dextrinized gruels, which are simply ordinary gruels the starch of which has been converted into soluble forms, leaving the cellulose and proteids of the cereal in a finely divided state. The effect of the different diluents will be men- tioned farther on. MILK-SUGAR SOLUTIONS. 1. Take 1 ounce of milk-sugar and 20 ounces ~| of water, and dissolve. I This makes about a Or 1 even tablespoonful of milk-sugar and y 5 - per - cent, sugar 7 V 2 tablespoonfuls of water, and dis- solution. solve. MODIFICATION OF MILK. 139 2. Dissolve 1 tablespoonful of milk-sugar in "| 6 Va ounces of water. I Makes a 6-per-cent. Or 1 ounce of sugar is to be dissolved in [ sugar solution. 16 V 2 ounces of water. 3. Dissolve 1 ounce of sugar in 14 ounces of ~) water. I Makes a 7-per-cent. Or 1 even tablespoonful in 5 Vs ounces of [ sugar solution, water. 4. Dissolve 1 ounce of sugar in 12 1 / 2 ounces of water. I Makes an 8-per-cent. Or 1 even tablespoonful in 4 1 /., ounces of ( sugar solution, water. 5. Double the strength of above milk-sugar ") Makes a 10-per-cent. (Formula No. 1). j sugar solution. ADDITION OF SUGAR TO MILK. In order to render milk palatable, sugar must be added in some form; hence cane-sugar or milk-sugar has been advised. Jacobi insists on the addition of cane-sugar, and he agrees with Biedert, who uses it in his cream-mixture. That cane-sugar certainly has some virtue can be seen by the fact that it is used extensively as a preservative in the manufacture of condensed milk. Cane-sugar. — Cane-sugar, being far sweeter than sugar of milk, it is advisable to use 1 / 2 the quantity that would ordinarily be used for sweetening with milk-sugar. Cane-sugar is advised in the treatment of constipation; frequently we find breast-fed babies who suffer constipa- tion, the cause being deficiency in sugar. In such cases giving a small lump (about 1 / 2 teaspoonful) of cane- sugar dissolved in a teaspoonful of sterile water (ordinary boiled water), and this given immediately before putting the baby to the breast, will make up the deficient sugar and frequently modify a distressing constipation without resorting to drugs. C ontra-indications to the Use of Sugar. — There are a great many conditions in which the addition of sugar is not only contra-indicated, but absolutely harmful. For 140 INFANT-FEEDING. example: If an infant suffers with colic and lias sudden attacks (paroxysms) of pain which disturb the infant's sleep, such an infant will be found with its legs drawn up to its belly, and besides it will utter shrieks while crying. The stools will usually be green and sour smell- ing, and the abdomen will be found greatly distended with gas from fermentation, and frequently the infant will have violent eructations. Such an infant usually receives an . excess of sugar. The treatment of such a case is the absolute discontinuance of susrar in the food. HOW SHALL WE SWEETEN If constipation has accompanied the infant's ferment- ative condition and has also preceded this attack of colic, then I advise adding glycerin to the milk. It has a very sweet taste and a pronounced laxative effect. Dose of Glycerin. — For some children half a tea- spoonful of glycerin added to each bottle will suffice; for others, I frequently use 1 teaspoonful to each bottle, rarely more. Glycerin has a pronounced antifermentative effect; being an oil, it is indicated in children requiring the addition of fat. It certainly has decided nutritive properties. SOLUTIONS USED FOR RENDERING COWS' MILK ALKALINE. Lime-water is the alkali usually selected for neutral- izing the acidity in cows' milk. It acts by partly neutral- izing the acid of the gastric juice, so that the casein is coagulated gradually and passes, in great part, unchanged into the intestine, to be there digested by the alkaline secretions. As it contains only 1 / 2 grain of lime to the fluidounce, the desired result cannot be attained unless at least a third part of the milk-mixture be lime-water. Instead of lime-water, 2 to 4 grains of bicarbonate of sodium may be added to each bottle, or, better still, from 5 to 15 drops of the saccharated solution of lime. MODIFICATION OF MILK. 141 This solution is made in the following way: — IJ Slaked lime, 1 ounce. Refined sugar, in powder, 2 ounces. Distilled water, 1 pint. Mix the lime and sugar by trituration in a mortar. Transfer the mixture to a bottle containing the water, and, having closed this with a cork, shake it occasionally for a few hours. Finally separate the clear solution with a siphon and keep it in a stoppered bottle. Bicarbonate-of-Soda Solution (Baking-soda). — Take 1 grain of soda bicarbonate to 1 / 2 ounce of water. Or 1 drachm of soda bicarbonate to 1 quart of water. This is the proper strength used for diluting milk. Quantity to be Used. — One tablespoonful of the last- named solution equals in strength 1 tablespoonful of ordi- nary lime-water. Both lime-water and soda-bicarbonate solution should be kept in very clean, well-stoppered bottles and in a cool place. The writer has seen better results by using bicarbonate of potassium (11 per cent.) solution. The addition of a half-teaspoonful to each feeding-bottle is well borne and beneficial where tendency to colic exists. CHAPTER XX. Water. Or all the necessities of an infant, water stands out most prominently. It will aid materially in clearing the mouth and gums and in quenching the thirst. It is cer- tainly diuretic, and water given regularly is one of our best laxatives. It is a good rule, and one that I insist upon, namely: to instruct every mother and nurse that a child, young or old, must receive water several times a day. Quantity. — An infant up to the first month shall re- ceive several teaspoonfuls of plain sterile (boiled) water, which has been allowed to cool, but by no means ice- water. This drink of water is best given either immediately after nursing or feeding or as soon after the feeding as possible. It is not necessary to awaken the child to give it a drink, but if it is not time for feeding and the infant is restless, a few spoonfuls of cool water will frequently com- fort it. When we desire to modify constipation, then water will be a most important factor, especially so when large, cheesy curds are found in the stool. Instances will be found in which some children will refuse water; in such cases the addition of a few grains of granulated (cane-) sugar will prove advantageous. Older children, over six months old, can, if properly de- veloped, take hold of a glass and be guided in the drink- ing or sipping of a wineglassful of water. I advise giving at least 3 wineglassfuls of plain sterile (boiled) water per day, especially during warm weather. (142) WATER. 143 The free dilution of children's nourishment with water is demanded upon the following additional facts: Only to a certain limit will pepsin be furnished for digestive purposes. Probably a portion of this is not entirely util- ized. A great quantity of water is necessary to assist in pepsin digestion. In artificial digestion albumin often remains unchanged until large quantities of acidulated water are supplied. Without doubt many disturbances of digestion are to be explained by a deficiency of water, certainly many more than are due to an excess of it, as it is so quickly absorbed. CHAPTER XXI. Bottle-feeding, ok Hand-feeding. Cleanliness. — The most important point to remember is that everything used in connection with "hand-feeding" must be scrupulously clean. To sterilize milk in a filthy bottle, or to put milk contaminated with stable filth or dirt from the udder of a cow, or milk containing pathogenic bacteria, into an absolutely clean bottle, is surely repulsive. Therefore, my first proposition is: "Clean everything that is associated with infant-feeding," from the milking of the cow, the surroundings of the cow, until the food is ready to be fed to our infants. This necessarily implies quite an amount of work, which I shall endeavor to detail later on. Amount to be Fed. — Ssnitkin (investigations at the Children's Hospital of St. Petersburg, quoted by Eotch) makes the following rule: "The greater the weight, the greater the gastric capacity." Ssnitkin's table of calculation shows that one one- hundredth of the initial weight should be taken as the figure with which to begin the computation, and to this should be added one gramme for each day of life. Illustration of Ssnitkin's Rule. Initial Weight. 3000 Gm. 4000 Gm. 5600 Gm. Early Days. 30 Gm. (About 1 oz.) 45 Gm. (About lioz.) 60 Gm. (About 2 oz. ) At 15 Days. 30 + 15 = 45 Gm. (About lh oz.) 45 + 15 = 60 Gm. (About 2 oz. ) 60 + 15 = 75 Gm. (About 2£ oz.) At SO Days. 30 + 30 = 60Gm. (About 2 oz. ) 45 + 30 = 75 Gm. (About 21 oz.) 60 + 30 = 90 Gm. (About 3 oz. ) (144) CHAPTER XXII. Feeding-table and Cream-mixtures. Age. Intervals of Feeding. Number of Times IN 24 Hours. Average Amount Each Feeding. Average in 24 Hours. 1st -week .... 1st month . . . 2d month . . . 3d and 4th mos. 5th and 6th mos. 2 hours 2 hours 2J hours 3 hours 3 hours 10 8 8 7 6 1 oz. l£ to 2 oz. 3 to 4 oz. 4 to 5 oz. 6 to 7 oz. 10 oz. 12 to 16 oz. 20 to 30 oz. 30 to 35 oz. 34 to 40 oz. The above is the feeding-table of George C. Carpenter (London). biedert's cream-mixtures. The following formulae are from the fourth edition of his book on "Infant-feeding," published in 1900: — Formula. Cream. Water. Milk-sugar. Milk. Casein. Fat. Sugar. Per Cent. Per Cent. Per Cent. 12 oz. Q dr. . . 12 oz. 4| dr. 12 oz. 4} dr. 12 oz. 4| dr. 12 oz. 4,\ dr. 8 oz. 3 dr. I. II. III. IV. V. VI. 4 oz. 4 Oil. 4 oz. 4 oz. 4 oz. 2oz. 4 oz. 8oz. 12 oz. 24 oz. 0.9 1.2 1.4 1.7 2.0 2.5 2.5 2.6 2.7 2.9 3.0 2.7 Cream. Milk. Water. Milk- sugar. Casein. Fat. Sugar. Per Cent. Per Cent. Per Cent. 1. 1st mo. giv. No. I*ij. 2. 2d mo. No. SiJ- No. 3. 3d mo. No. giv. No. 4. 4th mo. No. gviij. No. 5. 5th mo. No. 3*ij. No. 6. 6th mo. No. 5*vj. Sviij - Is equiv- 1 ^ ss - alent to 1U N Is equiv- 1 4 JN0 - alent to x '* No. Is , e q«; v - 1.8 alent to No- 'iTlo" ™ No- ISt " 2.4 2.6 2.7 2.9 3.0 3.0 (145) 3.8 3.8 3.8 3.8 3.7 4.0 146 INFANT-FEEDING. The latter are known as Biedert's cream-mixtures, and are quoted by A. Jacobi. 44 According to recent milk-analyses, it is necessary to take 6 per cent., which is equivalent to 5 1 / 2 drachms of sugar to 12 ounces of water. It has also been shown that cane-sugar in the same quantity as milk-sugar can be used. In using Formula 5, especially if an infant is constipated, it is advisable gradually to substitute milk for the water; thus we take away 1 ounce of water, and add 1 ounce of milk, until our formula is: — Cream. Sugar-water. Milk. 4 ounces. 4 ounces. 20 ounces. and gradually arrive at a whole-milk feeding; in other words, give pure cows' milk undiluted. Biedert claims that frequently diluted cows' milk was not well borne, especially on weak stomachs, and the change to the cream- mixture resulted in decided benefit. Moreover, he be- lieves that the cream-mixture is assimilated far better than the diluted milk-mixtures not containing cream. Thus he claims that the cases of constipation alter- nating with diarrhoea and lastly mucous enteritis are those in which the cream-mixture will render satisfaction; but he advises that a definite rule must prevail regarding the amount of fat contained in the cream, and furthermore that an 8- to 10-per-cent. cream be used. biedert's directions for making his cream. From 1 to 2 quarts of milk are put into a broad jar (glass) on the ice, for no longer than two hours. He then removes with a flat spoon from 3 1 / 2 to 7 ounces of the thin white creamy layer over the bluish mass of milk. In removing the above quantity a small portion of the milk will be removed with it. In cases of severe constipation Biedert insists on removing pure cream. 'Therapeutics of Infancy and Childhood." CREAM FEEDING. 147 The above Formula I is for the first month, Formula II is .for the second month, Formula III is for a child from three to four months, Formula IV is for fourth to fifth month, Formula V is for the sixth to seventh month, and Formula YI is for the eighth to tenth month. It is understood that, while feeding, the general condition of the child is the criterion, and thus we shall frequently be compelled to change the formula for in- dividual requirements, some infants requiring far more cream than the above-mentioned formulas give them for their age and their weight, whereas the great majority will require a modification of far less cream than the above-given formulae for their age and weight. The indiscriminate feeding of cream, to strengthen the laby, cannot be too strongly condemned. Many a dyspeptic owes his trouble to overfeeding by a too good mother or nurse. When cream is added, and the proportion of fat or proteid is too large, vomiting will result. Stuffing delicate children with cream, regardless of their digestive power, cannot be too strongly condemned. When improper food is given, and the infant's stomach is overtaxed, the excess of food irritates and may cause vomiting. If, however, the food remains, then the gastric mucosa is inflamed by bacterial fermentation of stag- nant food. This may result in fermentative gastritis and cause chronic enlargement of the stomach, or diarrhoea. CHAPTER XXIII. Home-modification of Milk, coit's decimal method (tuttle, gallaudet). This is the simplest and easiest-worked method of home-modification yet suggested. It is based on the metric system, and all the calculations are made in deci- mals. Three solutions are required: 1. A decimal (10 per cent.) cream, or superfatted milk for introducing the fat. 2. A saccharated (10 per cent.) skimmed milk for intro- ducing proteids not carried by the cream. 3. A standard (10 per cent.) sugar solution for introducing the lactose not carried by the cream or the skimmed milk. Solutions 1 and 3 only are required when the proteid percentage is small. As the child grows older, and a higher proteid percentage is necessary, solution 2 is required also. Decimal cream is produced by allowing a quart of ordinary fresh milk from a mixed herd to stand on ice for fifteen hours, and at the end of this time one-fifth of it is taken from the top. This averages 15 per cent, of fat, and loses about 1 / 2 per cent, each of sugar and proteids. If to this we add 1 / 2 its volume of water, a decimal cream is obtained, analyzing: 10 per cent, of fat, 2.33 per cent, of proteids, and 2.66 per cent, of sugar. From this the following formulae, showing the amounts of proteids and lactose coincidently introduced with any definite fat-per- centage, are easily deduced: — Decimal cream in introducing 4 per cent, of fat also introduces 1 per cent, of proteids and 1 per cent, of lac- tose. Decimal cream in introducing 3.5 per cent, of fat also introduces 0.8 per cent, of proteids and 0.9 per cent. (148) HOME-MODIFICATION OF MILK. 149 of lactose. Decimal cream in introducing 3 per cent, of fat also introduces 0.7 per cent, of proteids and 0.8 per cent, of lactose. Decimal cream in introducing 2.5 per cent, of fat also introduces 0.6 per cent, of proteids and O.Y per cent, of lactose. Decimal cream in introducing 2 per cent, of fat also introduces 0.5 per cent, of proteids and 0.5 per cent, of lactose. Saccharated shimmed milk depends on the fact that skimmed milk analyzes 4 per cent, of proteids and 5 per cent, of sugar. Five per cent, more of lactose is added simply for convenience of calculation. This means add- ing 1 ounce, by weight, of lactose to 20 ounces of skimmed milk. Our solution then analyzes: proteids, 4 per cent.; and lactose, 10 per cent. If we wish to add 1 per cent, of proteids, we use one-fourth of the total food required from solution 2; if 0.5 per cent, of proteids, one-eighth, etc., always remembering that we introduce coincidently two and one-half times as much sugar. The f ormulse here deduced are also plain: — Amount of food in cubic centimetres X 1 / 8 (saccha- rated skimmed milk) adds proteids, 0.5 per cent.; and lactose, 1.25 per cent. Amount of food in cubic centi- metres X V 4 (saccharated skimmed milk) adds proteids, 1 per cent.; and lactose, 2.5 per cent. Amount of food in cubic centimetres X 3 / 8 (saccharated skimmed milk) adds proteids, 1.5 per cent.; and lactose, 3.75 per cent. Amount of food in cubic centimetres X 1 / 2 (saccharated skimmed milk) adds proteids, 2 per cent.; and lactose, 5 per cent. Standard sugar solution is prepared by dissolving 10 per cent, of lactose in sterile water, or 2 ounces, by weight, in 20 ounces of water. In calculating f ormulse four facts only are necessary: the quantity of food required; the percentage-formulas required; that the standards, except the proteids, are 10 per cent.; and the quantity of other constituents intro- duced with the standards. 150 INFANT-FEEDING. With these facts in mind, all that is necessary further is to reduce the quantity expressed in ounces to cubic centimetres by multiplying by thirty, and to multiply this product by one-tenth of the constituent to be introduced. Examples with and without the introduction of extra pro- teids will be given: — Single Feeding. Fat. Proteids. Sugar. Per Cent. Per Cent. Per Cent. Quantity, 2 oz. Formula desired 2.0 0.50 6.00 Oz. 2 X 30 = 60 c.cms. X 0.2 = 12 c.cms. decimal cream, adds 2.0 0.50 0.50 Leaves 0.0 0.00 5.50 Oz. 2 X 30 = 60 c.cms. X 0.55 = 33 c.cms. sugar solution, adds 5.50 Working formula: 12 c.cms. decimal cream. 33 c.cms. standard sugar solution. 15 c.cms. water. 60 c.cms. One Day's Food. Fat. Proteids. Sugar. Per Cent. Per Cent. Per Cent. Quantity, 35 oz. Formula desired 4.0 1.0 6.50 Oz. 35 X 30 = 1050 c.cms. X 0.4 = 420 c.cms. decimal cream, adds 4.0 1.0 1.00 Leaves 0.0 0.0 5.50 Oz. 35 X 30 = 1050 c.cms. X 0.55 = 577.50 c.cms. sugar solution, adds 5.50 Working formula: 420.00 c.cms. decimal cream. 577.50 c.cms. standard sugar solution. 52.50 c.cms. water. 1050.00 c.cms. GENERAL RULES FOR BOTTLE-FEEDING. 151 One Feeding. Fat. Proteids. Sugar. Per Cent. Per Cent. Per Cent. Quantity, 5 oz. Formula desired 4.0 1.50 7.00 Oz. 5 X 30 = 150 c.cms. X 0.4 = 60 c.cms. decimal cream, adds 4.0 1.00 1.00 Leaves 0.0 0.50 6.00 Oz. 5 X 30 = 150 c.cms. X h = 18.75 c.cms. skimmed milk, adds 0.0 0.50 1.25 Leaves 0.0 0.00 4.75 Oz. 5X30 = 150 c.cms. X 0.475 = 71.75 c.cms. sugar solution, adds 4.75 Working formula: 60.00 c.cms. decimal cream. 18.75 c.cms. saccharated skimmed milk. 71.25 c.cms. standard sugar solution. 150.00 c.cms. General Rules for Bottle-feeding. Age of Child. Frequency or Interval, of Feeding. Number of Feedings in 24 Hours. Average Amount for Each Feeding. Average Amount in 24 Hours. From its birth until it is 1 month old. 2 hours. 10 1 to 2 ounces. 10 to 20 ounces. 1 month until 2 months. Every 2| hours. 8 2 to 2J ounces. 16 to 24 ounces. 2 to 4 months old. Every 3 hours. 6 or 7 3£ to 4 ounces. 20 to 26 ounces. 4 to 6 months old. Every 3 hours. 6 5 or 6 ounces. 30 or 36 ounces. 6 to 9 months old. Every 3J to 4 hours. 5 8 ounces. 40 ounces. 9 to 12 months old. Every 4 hours. 5 8 ounces. 40 ounces. 152 infant-feeding. Rules for Feeding. For a Child at Birth. Formula 1.— The newborn infant's food should consist of (home-modification): — Fat 1.0 Cream . . , 2 ounces. Sugar 5.0 Milk 2 ounces. Proteids 0.75 Lime-water 1 ounce. Reaction alkaline. Water 15 ounces. Milk-sugar 6% drachms. The above formula (1) is to be divided into 10 feed- ings of 2 ounces each, or 60 cubic centimetres each, and should be heated for 20 minutes to 16 7° F., though Prof. Russell, of Wisconsin, has proved by experiment that tubercle bacilli is destroyed at 140° F., which temperature may answer when a good source of milk is found. The cream must contain at least 10 per cent, of fat. This is known as a decimal cream, and can be referred to under the heading of "Cream for Home-modification." Formula for Home Use. Child 1 Month. Formula 2. — Take of: — Fat 2.0 Cream 4 ounces. Sugar 5.0 Lime-water 1 ounce. Proteids 0.75 Water 15-25 ounces. Lime-water. . .5.0 Milk-sugar 6% drachms. The above quantity is to be divided into ten feed- ings, and heated for 20 minutes to 167° F., and the in- fant to be fed once every two hours. In Formula 2 we have added more cream and purposely left out the milk. If the infant thrives on this mixture, then we can sub- stitute 1 ounce of milk instead of 1 ounce of water. Some children will not be satisfied with less than 3 to 4 ounces; there is no reason why they should not receive the above quantity if their general condition warrants it. After the end of the second month the quantity of food can be increased if the infant's appetite, sleep, stools, and general condition warrant it. Thus, instead of feed- SCHEDULE FOR FEEDING AND FORMULA. 153 6 H < "A H Ph e5 P « 02 H to B 85 - 'A PhPh i. 1st and 2d day. 5.0 4-8 125-250 ii. 3d to 7tb day. 2.0 6.0 ' 0.60 ' 10-15 310-460 in. . 2 to 4 weeks. 2.5 6.0 0.80 20-30 620-930 IV. 1 to 3 months. 3.0 6.0 1.00 22-36 680-1110 V. 3 to 4 months. 3.5 6.0 1.25 28-38 870-1180 VI. 4 to 6 months. 4.0 6.0 1.50 32-38 990-1180 VII. 6 to 9 months. 4.0 7.0 2.00 34-42 1050-1300 VIII. 9 to 12 months. 4.0 6.0 2.50 38-45 1180-1400 IX. 12 to 15 months. 4.0 5.0 3.00 40-50 1240-1550 X. 15 to 18 months. 4.0 5.0 3.50 45-50 1400-1550 XI. 18 months (whole milk). 3.5 4.3 4.00 45-50 1400-1550 Formula Obtained by Diluting 12-per-cent. Cream. Dil. 5 times with 6-per-cent. sugar sol. : Dil. 4 times with 6-per-cent. sugar sol. : Dil. 3 times with 7-per-cent. sugar sol.: Dil. 2jt times with 7-per-cent. sugar sol. : Dil. 2 times with 7-per-cent. sugar sol. : By diluting five times is meant one part of the cream and five parts of the sugar solution, etc. Fat. Sugar. Proteids Per Cent Per Cent. Per Cent. II. 2.0 6 0.60 III. 2.5 6 0.80 IV. 3.0 6 1.00 V. 3.5 6 1.20 VI. 4.0 6 1.30 Formula Obtained by Diluting 8-per-cent. Cream. Dil. once with 10-per-cent. sugar sol.: Dil. 1 J times with 7-per-cent. sugar sol. : Dil. 3 times with 7-per-cent. sugar sol. : Dil. 7 times with 5-per-cent. sugar sol. : Fat. Sugar. Proteids Per Cent . Per Cent. Per Cent. VII. 4 7 2.00 XII. 3 6 1.50 XIII. o 6 1.00 XIV. 1 5 0.50 Formula Obtained by Diluting Plain Milk. Dil. once with 8-per-cent. sugar sol. Dil. 3 times with 5-per-cent. sugar sol. Dil. 7 times with 4-per-eent. sugar sol. Dil. 11 times with 4-per-cent. sugar sol. Fat. Sugar. Proteids. Per Cent. Per Cent. Per Cent. XV. 1.80 6 2.00 XVI. 0.90 5 1.00 XVII. 0.45 4 0.50 XVIII. 0.30 4 0.34 154 INFANT-FEEDING. ing a bottle of Formula 2, we simply add 1 ounce of milk for the third month to Formula 2. Frequently the ad- dition of 1 or 2 ounces of sterile water to the formula will give a larger bulk and satisfy the infant. As every in- fant's appetite and gastric capacity is different, we must carefully note the condition of the baby after its feeding before resorting to fixed rules. Formula for Home Use. At 4 Months. Formula 3. — Take of: — Fat 3.5 Cream 7 ounces. Sugar 6.5 Milk 1 ounce. Proteids 1.5 Lime-water 1 ounce. Lime-water. . .5.0 Water 25-32 ounces. Milk-sugar 6*4 drachms. Divide into eight bottles; heat as above to 167° F.; feed every three hours. Formula for Home Use. From 9 to 12 Months. Formula 4. — Take of: — Fat 4.0 Cream 8 ounces. Sugar 7.0 Milk 7% ounces. Proteids 3.0 Lime-water 1 ounce. Lime-water. . .5.0 Water 20-30 ounces. Milk-sugar 6% drachms. The above to be divided into five feedings, heated to 167° F., and one bottle fed every four hours. A schedule for feeding an average healthy infant from birth upon modified cows' milk, showing percentages of fat, sugar, and proteids, and the daily quantity (Holt), is given on page 153. Clinical Illustrations of How to Feed (from the Author's Private Records). Case I. — Baby V., was referred to me for treatment April 3, 1901. The child was 3 y 2 months old at time of commencing treat- ment, and weighed 8 pounds and 10 ounces. History: Breast-fed about two weeks; since then fed on milk CLINICAL ILLUSTRATIONS OF FEEDING. 155 diluted with water and milk-sugar; food was steamed forty minutes. Child had always been constipated, always cries, and suffers with colic. Gave barley and condensed milk with lime-water; child seemed to do well; weight was about 10 pounds. After several weeks cream was added to the food. After this addition of cream the child vom- ited and cried, had severe colic, was restless by day, and had in- somnia at night. Its bowels were so disturbed that all milk was stopped. Barley-water was the only food tolerated. Then cereal milk was prescribed. The cereal milk was not retained; child vom- ited after each feeding, then was constipated, which alternated with greenish, dark stools. Infant was emaciated; the stools contained mucus. Physical Examination: Very emaciated child; temperature, 100° F.; abdomen distended, very flatulent; skin dry, lost elasticity; herpetic eruption on lips and around anus; pulse, 140 and feeble; throat clean; lungs normal; heart-sounds very feeble; left inguinal hernia. Diagnosis: Athrepsia resulting from chronic gastric catarrh. Food Ordered: Pure cows' milk 2 ounces. Oatmeal -water 2 ounces. Granulated sugar y z teaspoonful. Peptogenic powder y 2 teaspoonful. Feed every three hours. Alternate with: — Pure cows' milk, Barley-water of each §ij. Granulated sugar 3ss. Peptogenic powder y 2 teaspoonful. Heat this mixture slowly for ten minutes, then boil one minute. Mother reports that the child takes food well, stools are yellow, and child passed a good night, but still has eructations and seems colicky. The food was continued, and the child gained ten ounces in seven days. Weight, April 3 8 pounds and 10 ounces. Weight, April 10 9 pounds and 4 ounces. Weight, April 17 9 pounds and 8 ounces. Weight, April 24 9 pounds and 14 ounces. Weight, May 1 10 pounds and 4 ounces. Weight, June 3 12 pounds and 5 ounces. Weight, June 15 13 pounds and 12 ounces. Weight, Dec. 20 19 pounds. 156 INFANT-FEEDING. Extract of malt was ordered, y 2 teaspoonful three times a day. Every week the formula was changed, commencing with: — Milk 2 ounces Barley-water or oatmeal-water. .2 ounces One week later I ordered: — Milk 2% ounces V Formula I. } Feed every three hours. Barley-water or oatmeal-water. .2% ounces Raw milk 3 ounces Barley-water or oatmeal-water. . 3 ounces Peptogenic powder 2 teaspoonfuls ' Granulated sugar y z teaspoonful Feed every three or three and one-half hours. I ordered this infant to be awakened by day for feeding, but not to be disturbed at night. When the child cried after feeding when 5 months old, instead of giving Formula III, I ordered: — Raw milk 4,y z ounces ~\ Barley-water 2% ounces I -o . • j ,, r Formula IV. Peptogenic powder y z measure , Granulated sugar y z teaspoonful J The above for one feeding. Feed every three or three and one- hours. Substitute oatmeal-water for barley-water every other day. Milk 5% ounces "j Barley-water 2 ounces Peptogenic powder y z measure Granulated sugar y z teaspoonful J Alternate with oatmeal-water. Feed every three and one-half or four hours. > Formula V. Case II. — Dorothy L. F., 11 months old, was referred to me for treatment on March 18, 1901, by Dr. H. J. The history elicited was : The baby is still nursing and appears undersized, very anaemic, and poorly developed. No evidence of teething; cannot walk nor talk. Has had summer complaint. Re- cently suffered with constipation. Had diarrhceal stools some time ago; stools were greenish in color, and contained curds and mucus. Has had a cough lasting three weeks; also sniffles. A restless sleeper, rarely sleeping more than one-half hour at a time during the day. Is frequently very raw between thighs and on buttocks. Child is very flatulent. CLINICAL ILLUSTRATIONS OF FEEDING. 157 Physical Examination: A very frail child; large abdomen; slight evidence of rickets; very feeble heart-action; lungs normal; spleen palpable; liver very much enlarged; colon distended, tym- panitic on percussion; muscles of extremities very flabby; bones very small; epiphyses of long bones very much enlarged; tongue coated; throat normal; some adenoids. Specimen of breast-milk sent to chemist for examination showed: — Quantity, about 2 ounces, or 60 cubic centimetres. Reaction slightly alkaline. Specific gravity 1.03105 Fat 1.22 Sugar 7.07 Proteids 0.98 Shows low fat and low proteids. The baby weighed about 4 y 2 pounds at birth, and weighed be- tween 12 and 13 pounds when 6 months old. It now weighs naked about 16 pounds. From the history I learned that the mother menstruated while nursing since her child was 4 months old. The infant's restlessness was evidently associated with this condition. The study of the chemical examination of the breast-milk which this child received easily- explains the poor development, the proteids -being less than 1 per cent., besides a very low percentage of fat being also partly responsible. Treatment: Absolute weaning from the mother's breast. Pure cows' milk, warmed to feeding temperature, or about 100° F., 6 ounces to be given at each feeding. Feed every four hours; strict observance of interval of feeding and careful attention to sterility of everything coming in contact with food or utensils to be used. Medication: One-half teaspoonful of malt-extract given three times a day. This food was not well assimilated, so I ordered y 2 measure of peptogenic milk-powder to be added to each 6 ounces of raw milk. Gradually heat in a saucepan over a small flame for five minutes, then heat more rapidly and boil for about ten seconds. Repeat every four hours. Prepare each bottle separately. Do not use the food a second time, if the bottle is not emptied at one feeding. My record three days later shows: Had a very good night. Better appetite, formerly took only 3 to 4 ounces, now takes almost 5 ounces. Did not moan last night. March 27th: Child looks better; bowels move twice naturally, 158 INFANT-FEEDING. and have a yellowish color, but no curds. Temperature, 99° F.; pulse, 120; respiration, 36. This feeding was continued for about three weeks, and owing to good results no changes were made. This is the mother's report, which I copy: — ■ April 8th: Had a good night; slept from 10.30 p.m. to 6.30 A.M. continuously. Bowels are splendid, yellow; three stools yesterday. Has a slight irritation of genitals; seems to be fumbling with the parts. Examination showed vulvitis, irritation due to scratching, slight eczematous intertrigo. Diet Ordered: To continue raw milk modified with peptogenic powder; in addition thereto beef -soup thickened with either hominy, sago, or farina. Feed two hours after milk-bottle once a day, pref- erably about noon. Give the child the white of a raw egg with sweetened water every other day. The child received soup, alter- nating the next day with the white of egg, in the following manner: — ■ Warm raw milk, modified with pep- togenic 6 ounces at 6 a.m. Milk, peptogenic 6 ounces at 10 a.m. Soup, thickened 6 ounces at 12 Noon. Milk, peptogenic 6 ounces at 2 p.m. Milk, peptogenic 6 ounces at 6 p.m. This food was well borne ; the child gained. To improve the ap- petite 1 minim of nux vomica was ordered three times a day, before three feedings. Warm or raw milk, modified by heating with peptogenic as di- rected above: — 6 ounces 6 a.m. 6 ounces 10 a.m. White of raw egg, sweetened 12 Noon. Milk with peptogenic 2 p.m. Milk with peptogenic 6 p.m. Malt-extract was discontinued every other week and an emul- sion of codliver-oil ordered; 25 per cent, of oil was given. Each teaspoonful of the emulsion contained 2 grains each of glycerophos- phate of lime and glycerophosphate of soda. May 14th: We discontinued giving peptogenic and simply gave the baby raw milk warmed immediately before feeding. The milk was thickened by giving zwieback and bread-crumbs. I also ordered steak-juice, fed several teaspoonfuls at noon with some bread- crumbs or cracker-dust, and roast-beef juice. Also ordered egg- CLINICAL ILLUSTRATIONS OF FEEDING. 159 crackers, bread and butter, and soup made with mashed peas in which meat was boiled. June 1st: Somatose 1 / 2 teaspoonful to be stirred with milk or soup; repeat the dose three times a day. Also ordered raw apple- pulp sweetened with sugar. June 20th: Discontinued raw white of egg, and gave half of soft-boiled egg, half of yolk and half of white, followed by bottle of milk at 10 a.m. Child now weighs 19 1 / 2 pounds. Treatment discontinued; child went to the sea-shore. I did not see the child until middle of September, three months later. Has had summer complaint; food changed; different milk used in country evidently the cause. Child now weighs 18 1 / 2 pounds. This child did not receive one drop of milk all summer, simply put on pea-soup, cocoa and zwieback, and Nestle's food. I ordered: — Farina boiled in milk. Rice boiled in milk. Use one-half milk and one-half water. Boil one hour or longer. Also some barley-soup, afternoon cocoa, or milk, in the follow- ing manner: — Milk 4 ounces. Water 4 ounces. Granulated sugar ... 1 teaspoonful. _ Lime-water 1 teaspoonful. Feed at 6 a.m. Feed at 10 a.m., same as above. Feed at 12 noon, soup made from chicken or beef thickened with barley. Milk 6 ounces. Chocolate or Feed at 2.30 p.m. -j Cocoa 2 teaspoonfuls. Granulated sugar ... 2 teaspoonfuls. . Water 2 ounces. Avoid all lumps in chocolate by rubbing up with hot water and gradually adding the milk. Heat over small flame and stir well. Feed at 6.30 p.m., milk thickened with egg-cracker or zwieback. This food was well assimilated, and then the following was added: Sliced apple, in the morning; pudding made from broken zwieback, some milk, and yolk of egg. 160 INFANT-FEEDING. September 30th: Shredded wheat, oatmeal, or farina with milk was allowed in addition to the afternoon cocoa or chocolate feeding above ordered. At noon chicken bouillon or soup, to which yolk of raw egg, well beaten, was allowed. In October we gave raw scraped steak on a soda-biscuit. Also ordered fresh vegetables, stewed or mashed peas, some spinach and cauliflower, and baked potato with butter. Bone-marrow, 1 teaspoonful three times a day, was ordered. The child made excellent progress. Teeth appeared, and the child is strong, well, and able to walk; no physical defect is visible; mentally the child is normal, and, indeed, to all appearances it is now a normal child. Case III. Dyspeptic Infant, Requiring Careful Bottle-feeding, now Perfectly Well.- — Baby Douglas C. M., child of a physician, was born May 29, 1901. Weighed at birth 9 pounds. Was breast-fed about two months. Owing to swollen breasts, the milk suddenly ceased. The child was weaned. Weight, 12 pounds. Stools normal at time of weaning. Hand-feeding with equal parts of milk and water was tried. As this was not well borne, Mellin's food was given. When first seen by me the infant had frequent attacks of vomit- ing; greenish stools, containing curds and mucus. Cries with colicky pains. Has constant intestinal fermentation. Infant at 4 months, while suffering with colic, was given: — Pure milk 14 ounces. -\ Barley-water 20 ounces. I Granulated sugar . . 4 teaspoonfuls. C Lime-water 7 teaspoonfuls. J Mix the above and divide into seven clean bottles. Place in a refrigerator until required. At feeding-time empty contents of a bottle into a saucepan and allow the food to come to a boil, then immediately remove from heat. When cooled to feeding tempera- ture, give it to the baby. Usual temperature is about 100° F., or blood-heat. In addition to the above food prune-water, made in the follow- ing manner, was ordered for thirst: — Fleshy prunes 1 dozen. Granulated sugar 3 teaspoonfuls. Water 2 teacupfuls. Mix together and boil for thirty minutes. Strain; feed when cold. Three to 6 teaspoonfuls can be given at one time. CLINICAL ILLUSTRATIONS OF FEEDING. 1G1 Fresh orange-juice, 3 teaspoonfuls one hour before milk-feeding, once a day. When seen a few days later it was found that the child had had, during the day, five greenish-yellow stools, containing cheesy curds. Ordered oleum ricini, 1 teaspoonful at 10 a.m. Feed at H-30 a.m. Feed at 2.30 p.m. Feed at 5.30 P.M. Feed at 8-30 p.m. If looseness continues, leave out sugar and substitute sac- charin, 1 / 2 grain to each bottle. Following day ordered: — Milk 20 ounces. -\ Barley-water 14 ounces. I ~ . , , , > Formula II. Sugar 4 teaspoonfuls. | Lime-water 7 teaspoonfuls. J Mix the above and divide into seven bottles. Scald each bottle before feeding. Barley-water is made by adding a tablespoonful of barley to a pint of water, boiling for five minutes, straining through cheese- cloth, and again adding enough water to make a pint. Infant cried and still seemed hungry after feeding, and the food was increased: — Whole milk 14 ounces. -\ Gravity cream ... 7 ounces. I ^^ m Sterile water 20 ounces. Cane-sugar 5 teaspoonfuls. J Mix the raw milk and cream in a clean bottle and add the water and sugar. Divide into seven bottles and keep in a refrig- erator until feeding-time. Keep bottles well stoppered with ab- sorbent cotton. Warm the bottles in hot water at feeding-time. Feed every three hours. The following day the child had no stool from 2 A.M. to 10 A.M. It seems better satisfied after the bottle, and takes food greedily. Food changed to: — Whole milk 20 ounces. -v Barley-water 14 ounces. I & ^ Sugar 4 ounces. | Lime-water 7 teaspoonfuls. J Divide into seven feedings. Feed every three hours. li 162 INFANT-FEEDING. As the above formula agreed, I ordered: — Whole milk 21 ounces. -j Barley-water 14 ounces. I Formula V. Sugar 4 teaspoonfuls. J Scald the milk and divide into seven feedings. Feed every two and three-fourths or three hours. Gained one pound during the week; has yellowish stools after each feeding; no vomiting; cries after feeding; appears dissatisfied. Changed feeding to: — Whole milk 20 ounces. ^ Barley-water 12 ounces. > Formula VI. Saccharin 3% grains. J Divide into seven feedings. Scald the raw milk with hot barley- water; then put in ice-chest until feeding-time. Boil two minutes in saucepan before feeding. Stool after each feeding, yellow, normal consistency, alkaline reaction. Child does not sleep well; seems hungry. Food changed to: — Whole milk 36 ounces. -j Barley-jelly 12 ounces. > Formula VII. Saccharin 3 y 2 grains. J Add 1 teaspoonful of cream to each feeding; discontinue if vomiting or if cheesy curds appear in stools. Scald milk as before. Feed every three hours. To make barley-jelly take 2 heaping tablespoonfuls of barley to 12 ounces of water, boil down, and again add enough water to make 12 ounces. Child still appears hungry after feeding. Stools less frequent. No vomiting. Has small, rose-colored spots on legs and face. Weight, 13 pounds. Feeding changed to: — Milk 42 ounces. •) _, , TTTTT I Formula VIII. Cream 2 ounces. j Divide into seven bottles and feed every three hours. If food does not agree add 1 teaspoonful of Fairchild's pepto- genic milk-powder to each bottle and heat for three minutes before feeding. Ordered two doses of calomel; 1 / 10 grain given. CLINICAL ILLUSTRATIONS OF FEEDING. 163 Child appears very bright. Has yellowish stools, no colic; ab- domen not distended. No evidence of vomiting. Sleeps well all night. Feeding changed to: — Milk 48 ounces. -) Cream 4 ounces. I Formula IX. Dextrinized wheat. . 7 teaspoonfuls. J Sweeten and heat as before. Divide into seven bottles. To make dextrinized wheat take 3 pounds of plain wheat-flour, boil in a bag for five hours, then dry in the oven, break open, reject the rind, and grate into powder. Child did not digest the dextrinized-wheat feeding. Changed to pure milk. Child now takes pure milk, 5 to 6 ounces. To relieve eczematous excoriation on buttocks, ordered: — 3 Calamin 3.0 Zinc oxide alb 3.0 Lanolin 30.0 Apply t. i. d. Child does not sleep well at night. Ordered milk steamed in double boiler for twenty-five minutes. Child cried very much during the last few days; had thin, yellowish stools after each bottle. To relieve thin, watery stools ordered: — - U Acid. HC1. dilut 2.0 Essence of pepsin 60.0 Sig. : Teaspoonful three times a day before feeding. Owing to an eczema on the buttocks after applying the salve, ordered equal parts of pulverized zinc oxide and talcum dusted over salve on buttocks. For the loose bowels ordered the rectum and colon irrigated with y 2 pint of chamomile-tea to which was added 10 grains of tannic acid. Temperature of irrigation, about 105° F. Oleum ricini, 1 teaspoonful, internally. Changed feeding to: — Milk 4 ounces. \ Barley-water . iy 2 ounces. I Formula X. Arrowroot ... 1 heaped teaspoonful. J Boil, and feed every three or three and one-half hours, alter- nating with thickened rice-soup or rice-water, 4 to 6 ounces at one feeding. Baby did very well on this diet, assimilated the food, and 164 INFANT-FEEDING. gained in weight. Had one or two yellowish, well-digested stools daily. After this improvement I ordered soups and white of egg. The child weighed, at 6 months, 18 pounds. The child is per- fectly well, walks and talks, and is now in his second year, with normal dentition. Effect of Heating Milk. Pasteurizing and sterilizing are still necessary evils. They are really more useful in keeping milk from spoil- ing than for any other purpose. The diseases transmitted by milk are very few, and are almost invariably due to contaminated water and utensils, and should be obviated by dairy inspection. Bacterial growth is what is to be feared in the milk, and this can be prevented by keeping the milk at low temperatures. If the infant's food or milk cannot be kept below 50° F., it should be pasteurized or sterilized as soon as possible, as, while the bacteria are killed by heat, the toxins they produce are not destroyed. Heating produces many changes in milk, some of which are not thoroughly understood. Boiled milk does not curdle with rennet as easily as raw milk, the cream is about one-third denser than the cream of raw milk, and the albumin is rendered insoluble. The following table of C. H. Stewart shows the per- centage of soluble albumin in milk at various tempera- tures : — Time of Heating. 10 minutes at 60° C. (140° F.) 30 minutes at 60° C. ( 140° F. ) 10 minutes at 65° C. (149° F.) 30 minutes at 65° C. ( 149° F. ) 10 minutes at 70° C. (158° F. ) 30 minutes at 70° C. (158° F. ) 10 minutes at 75° C. (167° F. ) 30 minutes at 75° C. (167° F.) 10 minutes at 80° C. ( 176° F. ) 30 minutes at 80° C. (176° F.) Soluble Albumin, Soluble Albumin in Fresh Milk. in Heated Milk. Per Cent. Per Cent. 0.423 0.418 0.435 0.427 0.395 0.362 0.395 0.333 0.422 0.269 0.421 0.253 0.380 0.070 0.380 0.050 0.375 none 0.375 none changes in milk caused by sterilization. 1g5 Changes in Milk Caused by Sterilization. In some late experiments made by Dr. E. M. Hies- land and published by Dr. B. C. Hirst 45 Dr. Hiesland found that by sterilization: 1. The albumin is coagu- lated. 2. Casein is less readily precipitated by rennet than in normal milk. Acid corrects this condition. 3. Fat is freed to a slight extent; fat not freed has a lessened tendency to coalesce. 4. Sugar undergoes some change, as shown by its lessened dextrorotatory power. The considerations suggested by a knowledge of the foregoing facts are: — 1. The coagulation of milk-albumin by sterilization may render the milk more difficult of digestion. 2. Sterilization interferes with the coagulability of milk by rennet, and presumably, therefore, with its digestibility by the gastric juice. 3. Free fat, as found in sterilized milk, is probably not readily assimilated in infant-food. The fat not free, being inclosed in a less easily destructible envelope, is probably slow of digestion. 46 On the question of sterilized milk the weight of evi- dence seems to show that the process, while preventing undue fermentation, so changes certain of the natural ferments and some of the fats that the milk is less easily digested and less nutritious. 47 At the New York Medical Association's Meeting, March 16, 1891, Brush read a paper on "Sterilized Milk," in which he objected to the sterilization of milk for in- fants' food because the process devitalized it. Among the other ways in which the value of the milk was lessened by sterilization, he said, was that the soluble albumin was made insoluble. He believed that a child raised on steril- ized milk would be less robust, and have a constitution 45 Medical News, January 31, 1891. 40 Medical Record, February 28, 1891. 47 North American Practitioner, June, 1892, from the "Year-book of Treatment" (Lee Brothers & Company). 1GG INFANT-EEEDING. that would more readily succumb to deleterious influences than one fed on natural milk. He contended that every human being required some living food, and that the cause of every scurvy was deprivation of such living food. The sterilization of milk for adults was of but little con- sequence, as they had other kinds of food; but it became a matter of the highest importance to an infant whose only food was milk. 48 Mateena Home Modifies. This is a glass apparatus for the modification of cows' milk at home, and consists of a glass vessel with pouring- Fie:. 22. lip, shaped like a graduate, holding sixteen ounces. The outer surface is divided by vertical lines into seven panels ; one panel shows the ordinary ounce graduation; the six others show six different formulae, so arranged as to be suitable for the entire first year's feeding. The accom- 48 Boston Medical and Surgical Journal, April 9, 1891. MATERNA HOME MODIFIER. 167 panying diagram is a more or less accurate reproduction of the arrangement of these panels. It is possible to obtain other percentages than those shown on the panels, by mixing what is called for by two adjacent formulae; as, for instance, equal quantities made according to Formulas 1 and 2 combined will give: fat, 2 1 / 4 per cent.; proteids, 0.7 per cent.; sugar, 6 per cent. 1. 3d-14th Day. Fat, 2 56. Proteids, 0.6 56 . Sugar, 6$. 2. 2d-6th week. Fat, l^if. Proteids, 0.8 56. Sugar, 6ji. 3. 6th-llth week. Fat, 3 f, . Proteids, 1 . Proteids, 256 . Sugar, 7f. 6. 9th-12th mo. Fat, 3^ f, . Proteids, 2J£ f . Sugar, 33-£ ^ . Milk Milk Milk Milk Milk Milk Cream Cream Cream Cream Cream Lime-water Lime-water Lime-water Water Water Water Lime-water Milk-sugar Lime-water Milk-sugar Water Water Cream Milk-sugar Milk-sugar Barley-gruel Milk-sugar Gr. sugar 1 I A As may readily be seen, all the formulas call for the same ingredients, excepting the sixth, which, instead of water, requires barley-gruel, and granulated sugar in place of milk-sugar. The method of using the apparatus is extremely simple. Having decided upon the formula to be used, that panel is to be observed to the exclusion of all the others. The respective ingredients are then poured into 1GS INFANT-FEEDING. the vessel, to tlie line below the designated substance. Thus, milk-sugar is put in first (or, in its absence, gran- ulated; and the line with the cross shows to what point the latter should be used), then the water, lime-water, cream, and milk in the order shown. The whole is then stirred, and the result will be a milk whose formula is at the top of the panel. The milk used with the apparatus should be good average milk. The cream should be the light centrifugal cream as obtained in bottled milk (16-20 per cent.). The water should be hot, to dissolve the sugar. The barley-gruel should be prepared in the usual way with Robinson's or ordinary barley. According to the age and size of the child, the vessel must be filled once, twice, or three times to obtain the quantity requisite for the twenty-four hours' feeding. The pouring into bottles and sterilization are then done as usual. Full directions, including a schedule for the twenty-four hours' feeding at the various periods of the child's growth, accompany the apparatus, which is sim- ple, accurate, and economical, making properly modified milk of practical value obtainable in places where it has hitherto been impossible to get it. The materna is adapted for home use only when the physician notes results. To intrust an apparatus of this kind into the hands of a mother or nurse not conversant with the difference in the percentage of fat contained in cream is not only wrong, but will prove disastrous to the infant so fed before many weeks are over. The author recently saw a case of dyspepsia brought about by feeding in this careless manner. On the other hand, the appa- ratus will serve as a guide to those physicians whose train- ing in percentage-feeding requires occasional assistance. A very practical "milk-modifying gauge" devised by Mitchell has been placed on the market. It can be pro- cured from the National Drug Company of Philadelphia. It is designed to aid those unfamiliar with home modi- fication, and is especially valuable to those distant from large cities with laboratories. CHAPTER XXIV. Sterilized Milk. E. G. Freeman, M.D., in a paper read before the Academy of Medicine, New York, May 11, 1893, says, of sterilization, that, when milk is sterilized at 212° F. (100° C), absolute sterilization is not obtained, but the milk is rendered less digestible than it is in the raw state, and physicians who have used sterilized milk as a regular food find that often infants so fed do not thrive. This clinical experience, chemists state, is occasioned by the many modifications produced in milk by this tempera- ture of 212° F., the starch-liquefying ferments being destroyed, the casein being rendered less coagulable by rennet and therefore being acted upon slowly and im- perfectly by pepsin and pancreatin, and the milk-sugar being destroyed; these chemical changes begin to be marked when a temperature of 176° F. (80° C.) is reached, and become more marked as the temperature becomes higher. In the Medical Age, September 25, 1893, it is stated that Dr. Fayel, of Caen, France, says boiled milk is more or less indigestible, and is in no respect safer than un- boiled milk; the temperature at which milk boils is in- sufficient to destroy microbes, and the milk is therefore not sterilized, while its density is increased by the boiling above that which is suitable for infant-digestion. In the Therapeutic Gazette, October 16, 1893, is a translation from a communication to the Societe de Mede- cine de Lyon, by Crolas. Crolas concludes that boiling milk relieves the milk of small quantities of butter, but has no action whatever upon the casein or lactose; that the boiling increases the quantity of soluble phosphates. (169) 170 INFANT-FEEDING. lie therefore believes that boiled milk as an article of food is equivalent, if not superior, to unboiled milk. At the meeting of the New York Academy of Medi- cine, Section in Pediatrics, May 12, 1892, Dr. A. Jacobi, in the discussion upon infant-foods, made the following points: — It was a great error to suppose that sterilized milk was anything like human milk; it required just as much modification as though it were not sterilized. Alkalinity in cows' milk was always suspicious, for it was evidence that it had been "doctored." The most dangerous alkali was bicarbonate of soda, for in milk thus treated the ptomaine-producing germs develop best. While pepsin was sometimes useful, he objected to its indiscriminate use; without an acid it was inert. Sugar was required in an artificial food, but he did not believe that milk-sugar was best. There was a close relationship between milk-sugar and lactic acid. The change from one to the other was very rapid. Some lactic acid was necessary for proper digestion, but an o^erquantity produced hyperacidity and indigestion. 49 Excerpt from an address at the Eleventh Inter- national Congress, Eome, Italy, April 4, 1894, by A. Jacobi, M.D.: — "I shall only dwell upon two articles which have taken an improper hold on the imagination of medical men and have almost been raised into subjects of super- stitious veneration. The use of milk-sugar in the place of cane-sugar in children's food to any extent beyond what there is in cows' milk, or its exclusive employment, is a source of acid gastric catarrh which afterward re- quires medicinal correction; it is transformed into lactic acid beyond need and proves a detriment, to the full conviction of all those who will give the subject proper attention. Thoughtful experience is as valuable an ob- ' Virginia Medical Monthly, June, 1892. CHANGES IN MILK CAUSED BY BOILING. 171 jective addition to our knowledge as a mere chemical or theological theory. "Next in order is sterilized milk, on which hundreds of thousands of babies are now being fed to the exclusion of everything else. JSTobody would teach nowadays the feeding on unchanged or unmixed cows' milk to babies as a proper course to take, — as a substitute for mothers' milk. But sterilized milk has been looked up to as an ob- ject of faith and treated as a pope among foods, infallible. To feed babies exclusively on sterilized milk has become the rage since it was recommended by gentlemen of the highest possible standing in science, but, as far as I know, little conversant with the art of treating well and sick infants. I speak so bluntly because I love babies, one and all. "Sterilized milk — pasteurized is inferior to it — is superior to unchanged cows' milk, still not human. Of 7 cases observed this winter of infantile scurvy, — -a nutri- tive disorder as far as we can make out, — there were 3 that had been fed, 2 exclusively, 1 for several months, on sterilized cows' milk." 50 The Chemical and Physiological Changes in Milk Caused by Boiling. 51 Milk consists of a multitude of cells suspended in serum. The cells are fat-cells, which form the cream; the remaining cells are nucleated, and of the nature of white blood-corpuscles. The serum consists of water, in which is dissolved milk-sugar and serum-albumin, with various salts, and, chief of all, casein. The cells, with the exception of the fat-corpuscles, are all living cells, and they retain their vitality for a considerable time after the milk is drawn from the mammary gland. 60 Medical Eecord, May 19, 1S94. 51 J. L. Kerr, M.D., CM., F.R.S.E., in the British Medical Jour- nal, December, 1895. 172 INFANT-FEEDING. There is reason for supposing that, when fresh milk is ingested, the living cells are at once absorbed without any process of digestion, and enter the blood-stream and are utilized in building up the tissues. The casein of the milk is digested in the usual way of other albuminoids, by the gastric juice, and absorbed as peptone. There is also absorption of serum-albumin by osmosis. The chemical result of boiling milk is to hill all the living cells and to coagulate all the albuminoid constituents. Milk after boiling is thicker than it was before. The physiological results are that all the constituents of the milk must be digested before it can be absorbed into the system; therefore there is distinct loss of utility in the milk, because the living cells of fresh milk do not enter into the circulation direct as living protoplasm, and build up the tissues direct, as they would do in fresh, unboiled milk. In practice it will have been noticed by most medical practitioners that there is a very distinctly appreciable lowered vitality in infants which are fed on boiled milk. The process of absorption is more delayed and the quantity of milk required is distinctly larger for the same amount of growth and nourishment of the child than is the case when fresh milk is used. Pasteurization of Milk. Heating milk to 75° C, as is done by many of the methods, does not sterilize, for the spores of the bacillus subtilis can withstand this temperature for several days. The spores will resist the temperature of 100° C. (212° F.) for six hours. Upon heating to 110° to 120° C. (230° to 248° F.) the milk will be thoroughly sterilized, but such heating causes a browning of the milk, and the cream-cells are apt to be broken and the fat or butter will rise to the surface. 52 Pasteurization with a temperature between 60° and 62 Molt-Zeitung. STERILIZED MILK. 173 80° C. (140° to 176° F.) destroys tubercle bacilli and, according to Van Geuns, destroys also the typhoid ba- cillus, the cholera bacillus, and the pneumococcus of Friedlander, and also most of the ordinary milk germs, and does not injure the milk. 53 Sterilized Milk. Sterilized milk is, according to Marr, 54 as badly borne in children's dyspepsias as ordinary milk, for, even when sterilized by Soxhlet's apparatus, milk is still prone to decomposition, and hence favors the decomposition-proc- esses present in the diseased digestive tract. Dr. B. Bendix 55 studied the question as to the rela- tive value of sterilized and unsterilized milk. In a paper recently published he arrives at the following conclu- sions: Sterilized and unsterilized milk have an equal value in nourishing both sick and well children. The change in taste and odor caused by the sterilization is no cause for the refusal of the same by infants, as steriliza- tion destroys both the pathogenic bacteria, as well as the bacteria causing fermentation and decomposition; so he believes that it is the duty of every physician to insist on substituting sterilized milk when breast-milk cannot be had, and, as he believes that sterilization does not cause difficulty of digestion, he prefers the latter to pasteurized milk. Koplik 56 studied the comparative value of sterilized, pasteurized, and other milks, and found that some weeks pasteurized milk and other weeks a sterilized milk would show advantages, which, however, would hardly decide for or against either method of preparing the food. The author believes that it is rather the food that should be looked after than the method of feeding it. 63 Medical Record, July 2, 1892. 64 London Medical Recorder. 55 Jahrbuch fur Kinderheilkunde, 38. 60 New York Medical Journal, April 13, 1895. 174 INFANT-FEEDING. Sterilization of Milk at 212° F. for Thirty Minutes. method of sterilizing (soxhlet method). Bottle-cleansing. — Always cleanse the bottles thor- oughly before using if they are new bottles. It is a good plan to give them one good washing by adding a pinch of common washing-soda to each bottle, boiling for at least five minutes in this soda-water, and then boiling for at least a quarter of an hour in ordinary water. The bottles are then turned upside down to allow the water to drain off. I then insert a large stopper consisting of non- absorbent cotton (ordinary cotton, from a dry-goods store, which is non-absorbent, is far better than the white ab- sorbent cotton). The neck of the bottle is stoppered at least three-quarters of an inch. Bottle-oaJeing. — If we wish to dry them hurriedly, then several of these bottles can be placed in a large frying-pan with a piece of pasteboard between each bottle, and baked thoroughly dry for about a half-hour.. This not only dries them, but baking them really sterilizes them. Place the bottles — previously filled with milk or the feeding mixture — in the rack, and set the rack in the sterilizing chamber, and cover up tight with the lid and hood. Fill the reservoir (pan) two-thirds full of water and place the apparatus over a moderate fire for one hour. If the milk is just from the cow, 40 or 50 minutes are sufficient (20 minutes for heating and 20 or 30 minutes for sterilizing). The sterilizer may be used on a gas-stove (turned low), kerosene-stove, or upon an ordinary cooking-stove; if over the last, the griddle should not be removed. You can tell by a bubbling sound that the sterilizer is working all right. If the water is not bubbling with regularity in- side, you need more heat. It must not be put on the fire STERILIZATION OF MILK. 175 without water in the reservoir, and the water should never be allowed to get lower than one inch from the bottom. With proper attention as to the quantity of water in the reservoir no further care need be given to the appara- Fig. 23. tus, or to the contents of the chamber, for the prescribed time. It is not necessary to place the bottles on ice after removing them from the sterilizer, but all bottles should 176 INFANT-FEEDING. be put into a refrigerator until taken out for feeding, leaving in the cotton plugs until it is feeding-time. The directions sent out with some sterilizers, that milk will keep for days, implies that infant's milk may be prepared for several days at once. To this I decidedly object. A great many authors have pointed out cases of Barlow's disease due to milk which had been sterilized and not used Fig. 24. for a very long time. Before feeding, the bottle is to be properly warmed by putting it into a small measure or bottle-holder and heating it with alcohol or gas to about the body-temperature of 98° or 100° F. Immediately be- fore using shake the bottle, so as to mix the cream and the milk, which invariably separate in a refrigerator; remove the cotton and draw on the nipple. CHAPTEE XXV. Pasteurized Milk. Booker states that certain germs may not be harm- ful to the baby, if introduced into its body, but are in- jurious to the milk. For example, bacillus lactis aerog- enes. These germs are destroyed at a low temperature. Booker does not believe that the disturbances claimed to be caused by the sterilization of milk are warranted; nor does he believe that sterilized milk per se causes scurvy. Preeman states that high-temperature sterilization causes chemical changes in milk: — Change in taste at 70° C. (158° F.). Chemists note changes at about 80° C. (176° F.). Preeman believes bottle-food to be a predisposing cause of scurvy. He states that a low temperature, pro- longed, acts as well in destroying pathogenic germs as the action of a high temperature for a short time. He advises 68° C, equivalent to 155° F., for 30 minutes, followed by rapid cooling. Such a temperature will de- stroy the germs of diphtheria, typhoid, tuberculosis, and other diseases, proved by the inoculation of a plate at laboratory temperature, showing no growth after twenty- four hours. Preeman does not believe that our present dairy can furnish a raw milk which is absolutely safe as an infant-food, because, he says, milk must be obtained by pressure on the teats of a cow, and these teats hang beneath an udder, which is covered with hair, and from the belly of the cow, which is also covered with this same hair covering. Moreover, this portion of a cow is par- ticularly liable to be soiled with dirt, as it comes in con- tact with the ground when the cow lies down. Its hairy 12 ( 177 ) 178 INFANT-FEEDING. covering, moreover, holds the dirt, which is gradually shaken out by friction. If the cow has loose stools, these run down the inner surface of the thigh and the posterior portion of the udder. The contamination dries on the udder, in the air, and during milking is apt to fall as dust in the pail. Moreover, the milk-ducts of the cow may contain many bacteria, although usually contami- nation from this source is not very great. Freeman fur- ther says: "The milkman's hands are almost never clean. His hands are employed in handling manure, and in attending duties involving contamination. Occasionally they are used during the day in waiting on some one sick with a contagious disease, and, when such is the case, the consumers of the milk are apt to suffer." The author read a paper by Prof. Adolf Baginsky, on "The Milk-supply in the Kaiser and Kaiserin Fried- rich Children's Hospital, in Berlin," before the Section on Diseases of Children, at Atlantic City, in June, 1900, wherein Baginsky says that, before milking a cow, the stable is cleaned with a damp cloth. All the dirt is re- moved, and finally the stable is cleaned with water. Prior to milking, the Swiss milkmen are compelled to thor- oughly cleanse themselves, giving especial attention to their hands. These are cleaned with soap and brush. Great stress is laid on washing the udder of each animal with warm soap-water, and drying with clean cloths. In this manner the infection with hair and stable-dirt is pre- vented. The milk is not allowed to remain in the stable until all the cows are milked, but as soon as a pail is filled it is at once removed to the dairy, thus preventing the danger of contamination with bacteria which are found in the air of the stable and which are very hard to destroy by sterilization. These are the bacteria of the hay- and potato- bacillus groups. Another vital point is that warm milk easily absorbs the various stable-odors, and frequently has a distinct "stable-flavor." If what Freeman claims might happen, — namely: PASTEDEIZED MILK. 179 the introduction of filth, manure, and f cecal matter into the milk during the milking process, — then it seems to me that such milk should be discarded entirely, for it is hardly conceivable that sterilizing or pasteurizing can modify milk contaminated in such a manner. Following the precepts of Professor Baginsky at Berlin, the main point is to insist on the strictest "stable-hygiene," and thus try to sterilize everything pertaining to the cow, the stable, and the utensils, and in this manner seek to obtain, by the strictest attention to cleanliness, "a strictly clean milk." Fig. 25. — Author's Choice of Feeding-bottle. Directions for Pasteurizing Milk. — Pasteurization is really sterilization at a temperature of 167° P. Experi- ence has shown that the bacteria usually found in milk and those which would be harmful for an infant can be destroyed by subjecting milk to a temperature of 167° to 170° F. for 15 to 20 minutes. For this purpose Free- man has constructed his pasteurizing apparatus (see Figs. 26 and 27), which, however, is rather expensive, although extremely useful. The author has used it and has been well pleased with the result. 180 INFANT-FEEDING. Freeman's pasteurizer consists of a metal pail into which a rack is placed holding the bottles exactly as is found in the ordinary sterilizing apparatus. This metal pail is partly filled with water — up to its first groove — and the water heated to the boiling-point. Until the water is brought to the boiling-point, the bottles are not intro- duced within the kettle. The bottles, previously filled with the required mixture of the infant's food, are held in readiness, and, when the water boils in the metal pail, the lid is removed, the rack with the bottles placed on the inside of the metal pail, and the heat turned off, or the pail is removed from the fire. The process consists in Fig. 26. allowing the water to cool, whereby the bottles and the milk get warm for a period of 30 to 45 minutes. After 45 minutes, the lid is again removed, the metal pail con- taining the bottles of milk is taken to a water-trough or sink, and the cold-water faucet, over which a piece of rub- ber pipe is fitted, is turned on, and the water permitted to flow on the inside of the pasteurizer. In this way there is a gradual displacement of the warm water by this cold water, until the water is all cold. After the bottles are sufficiently cooled, they should be removed to the refrigerator. The rapid cooling of the bottles is as important as the pasteurization by the heat. Pasteurized milk should be kept no longer than twenty- PASTEURIZED MILK. 181 four hours. We can pasteurize in other ways with any ordinary sterilizing apparatus. Thus, the Arnold steam- sterilizer (see Fig. 23), leaving the hood off, can be util- ized for this purpose. To be sure that we are attaining the correct temperature, we can insert a special ther- mometer, which is made for sterilizing bottles. It can be procured from any chemist or from the Arnold Sterilizer Company. To pasteurize with any ordinary sterilizer, set a ther- mometer into one bottle and put the sterilizer on a brisk fire until the thermometer reaches 170° F. Then remove Fig. 27. to the back of the stove, take out the thermometer, stopper the bottle that contained the same, and cover with a hood or the lid of the tin pail for fifteen minutes. Then fill the inside of the pail with hot water around the bottles as near to the top as possible, remove to the sink, and allow a stream of cold water from the faucet to displace the warm water. A point worth noting is that the cold water must not be allowed to splash on the hot bottles, other- wise it will crack them. It usually takes about ten min- utes to gradually displace the hot water in the tin pail or kettle used as a sterilizing chamber, after which the bottles of milk are to be placed in a refrigerator and left there 182 INFANT-FEEDING. until ready for use. It is understood that each bottle is to be warmed to about a body-temperature of 98° to 100° immediately before feeding. In a letter recently received by the author Prof. Victor Vaughan says he does not believe that milk is rendered more digestible by sterilization or pasteurization. He thinks that if milk could be obtained under complete aseptic precautions, sterilization, as a preparation for in- fant-feeding, would not be necessary. However, either sterilization or pasteurization is imperative when market milk is used, because this is seldom or never obtained under aseptic precautions. Some people have an idea that it matters not how filthy a milk is, or how many germs it may contain, if it be pasteurized or sterilized it becomes a fit food for children. This is not true, because, in the first place, even prolonged boiling does not kill the spores of all bacteria; and, in the second place, the chemical poisons produced by certain germs are not altered by the temperature of boiling milk. After milk has been either sterilized or pasteurized it should be kept at a low tem- perature before being fed to the child. This should be regarded as a necessary procedure in the preparation of infant-food. The fact that milk in which the colon germ has already grown abundantly cannot, by any process of sterilization or pasteurization, be rendered fit food for children should be emphasized. The toxin of the colon bacillus may be heated to 180° C. (356° F.) for half an hour without having its poisonous properties diminished. If clean milk be obtained and pasteurized at from 140° to 158° C. and then kept at a low temperature until fed to the child, it furnishes the best food which it is possible for us to obtain under ordinary circumstances. CHAPTER XXVI. Tyndallization. "When milk is subjected to a temperature of 212° F. for from 15 to 20 minutes on three successive days, such process is called tyndallization. When such a procedure is instituted, we certainly obtain the "absolutest sterility possible" of the milk. Such milk, however, is not adapted for infant-feeding, owing to the changes brought about by this continued application of heat in rendering the albuminoids and salts contained in the milk more difficult to digest. Milk subjected to this tyndallization has all the dis- advantages of a prolonged sterilized milk or milk-mixture. My experience is decidedly against such continued heating of milk, and I am sure that many cases of scurvy can be traced to the lack of fresh albumin and casein assimilated. It is certainly peculiar that in spite of the experience of many noted men, the author has recently seen a de- cided improvement in a child suffering with scurvy when the food was changed from sterilized milk to a raw-milk mixture, the milk-mixture being merely warmed to a feed- ing temperature. Barlow's disease can frequently be traced to improper feeding, especially when mothers are permitted to use their experience in making up their own feeding-mixtures. Children are more frequently starved than will be ordi- narily admitted, and, were it possible to examine the food given to the average infant and compare it with a stand- ard breast-milk suited for the age of the infant, we would soon learn that our crude methods resulted in positive harm, the result of which years of proper medication and feeding will hardly be able to remedy. (183) 184 INFANT-FEEDING. The vital point to remember is to get the child prop- erly started, and we must not be discouraged if our first feeding-mixture is not properly digested or assimilated. In such instances we will soon learn which elements of our food require more proper modification and elimina- tion, especially so if the stools are studied. Tyndallization will permit milk to be kept for months, and is just such milk which, fed to weakened children, will ultimately cause Barlow's disease or its allied conditions. While in Berlin several years ago I was given milk which had been sterilized six months previously. While it is true the taste did not betray the length of time that the milk had been kept, it can be easily seen that certain chemical changes will develop, altering the character of the food. It is my belief, founded on extensive experience, that sterilized milk, continually fed, to the exclusion of raw milk and raw beef-juice, will ultimately result in rachitis or scurvy. CHAPTEK XXVII. Nipples and Bottles. Attention to this portion of the feeding apparatus is very important, as the cause of sore mouth and tongue and gums can frequently be traced to a filthy nipple. CM Fig. 28. Such infections can he easily avoided in the following manner: The nipples are to be boiled for about ten or fifteen minutes in a so-called nipple-sterilizer (see illus- tration, Pig. 32), placed in a tin pail of plain water to which a pinch of salt has been added. After boiling in this manner the nipple should be put into a tumbler of plain, sterilized (boiled) water and allowed to soak until (185) 18G INFANT-FEEDING. it is time to use it. It is advisable to boil every nipple immediately after removing it from the feeding-bottle, turning it inside out, placing it in the sterilizer, and steaming it for 15 or 20 minutes. In this manner all Fig. 30. Fig. 31. pathogenic bacteria are destroyed, and all particles of milk which adhere to the rubber are removed. Such nipples will not be the cause of stomatitis or other infectious mouth disorders. NIPPLES AND BOTTLES. 187 The clioice of a nipple is another important matter. My preference has always been for a black-rubber nipple, and it is a very wise point to use a nipple no longer than one week; in other words, old, worn nipples are useless for the proper management of infant-feeding. Black rubber is softer than white rubber; most white rubber is supposed to contain lead; hence a decided reason for not using it. Nipples Recommended. — One of the best nipples made is the so-called anticolic nipple. This nipple has a ball- shaped top, which enables a baby to take a firm hold; it has three small holes, which give an easy flow of milk, and regulate a slow meal. Nipples having very large openings, which will permit a baby to finish a 6- or 8- ounce bottle of food in five or six minutes, are useless, and this gulping of food is really the cause, or one of the causes, of infantile colic. I have used another nipple, but it is much harder to clean, and unless all precautions for sterilization are care- fully noted it should not be used; yet, in the hands of the intelligent or where we have a trained nurse, it can be safely recommended. It is called the "Mizpah." This nipple has also a very small puncture, so that the baby gets the food slowly. The "swan-bill" nipple and the long French nipple I also like. I have noted just as good results as with the above-mentioned kinds. Ventilated Nipple. — A nipple very highly spoken of is the ventilated nipple made by Ware, of Philadelphia, which has a small opening or valve on the side, and, as the milk is drawn in from the bottle, it permits air to enter, thus preventing a vacuum from being formed. It is also supposed to be non-collapsible, and is highly rec- ommended by those who have used it. The only objec- tion — already offered — is that all nipples must not only be practical for use, but must be capable of thorough sterilization. 188 INFANT-FEEDING. Odor of Nipples. — Children will object most de- cidedly to nipples having any odor or taste; hence it is a good plan to boil every new nipple before using it. Fig. 32. — Nipple-sterilizer. The nipple-sterilizer (see Fig. 32) is a very conven- ient little arrangement made by Ware, of Philadelphia, and resembles a coffee-strainer with a lid. It is neat, tf*™^*, cheap, and serves its purpose admirably for the steriliza- tion of the nipple. The bottle-brush has a long handle and bristles for cleansing the bottles. This brush should be used before Fig. 34.— Bottle-brush. the bottles are put in the soda solution, and serves for cleansing the inside of the feeding-bottles. It is un- derstood that the brush can itself harbor bacteria and particles of milk removed while cleansing. It is therefore FEEDING-BOTTLES. 189 important that the brush should be thoroughly boiled in a washing-soda solution after each use. Fig. 35. Feeding-bottles. The long 8-ounce feeding-bottle, or so-called feeding- tube, which is illustrated, is certainly a unique bottle for feeding; as it has no corners and no useless rims, besides Fig. 36. being smooth on the inside, it can be very easily cleaned. All bottles having angles and depressions should be avoided. The boat-shaped bottle is also very good, but much harder to clean. 190 INFANT-FEEDING. My preference has always been for two kinds of bottles: 1. Those holding four ounces and graduated on one side in both ounces and tablespoons; this saves much time and trouble. 2. Bottles holding eight ounces and divided off into 16 tablespoonfuls or 8 equal ounces. Exactness of Ounces. — It may not be out of place to ask each physician to insist on having the graduated ounces on an infant's feeding-bottle measured with an Fig. 37. — Baby-comforter. Not Advised by tbe Author. accurate graduate, obtainable at every drug-store. In many instances the author noted feeding-bottles wherein the ounces indicated were very unequal, and one partic- ular bottle, graduated to eight ounces, held twelve ounces. Long Rubber Tubes. — Most prominent pediatrists agree that the long rubber tubes are a convenient place for harboring micro-organisms, and they have been uni- versally condemned. CHAPTER XXVIII. Dextrinized Gruels. We have previously referred, in the section on "Addi- tional Foods during the "Nursing Period/' to the method of making flour-ball. In some instances, especially where digestion is subnormal, beneficial results will follow the dextrinizing of infant-foods. Thus, the starch of the gruel is held in solution, and the remaining cellulose and proteids of the cereal are left to act on the curds. Method of Dextrinizing. — Prepare the wheat-, barley-, oatmeal-, or rice- flour by adding a tablespoonful of the same to a pint of water, adding a pinch of salt, and boiling the same for from fifteen minutes to one hour. This will make a gelatinous solution, and hence the name of barley- jelly, rice-jelly, oatmeal-jelly, or wheat-jelly. "We allow this jelly to cool, and when cool enough to be tasted we can add a diastase, such as cereo; or taka-diastase, made by Parke, Davis & Co. ; or the Forbes diastase. When a small quantity of this diastase is added to the jellies above mentioned, they lose their thickness, and become very thin. They can easily be strained through cheese-cloth, and some water added to make up for the loss by evapora- tion during the boiling. This jelly, or gruel as it is some- times called, made from either barley-, rice-, wheat-, or oat- jelly, is to be used with the milk after the diastase is added. In certain diseases, where milk is not well borne, such as dyspepsia (dyspeptic vomiting) or in summer com- plaint, where the giving of milk is prohibited, feeding the dextrinized gruels for several days will be found, not only very useful, but very healthful. In making this dex- trinized gruel, small particles will be seen floating, which settle out upon standing. These particles consist of the (191) 192 INFANT-FEEDING. cell-walls and the proteids of the cereal, and cut the curds of the milk into fine pieces, when the curds begin to shrink under the combined action of rennet and acid. In using this diastase we aim at breaking up the tough curd in cows' milk by purely mechanical means. Henry D. Chapin {Journal of the American Medical Association, July 14, 1900) says: "The next important step is to get the cows' milk as nearly as possible in the same physical condition as mothers' milk. The diluent I prefer to use is a wheat-, barley-, or oatmeal- gruel, the starch of which has been digested or dextrinized by the action of diastase. A heaping tablespoonful of flour, made from a cereal, is boiled with about a pint and a half of water for fifteen minutes. It is then removed from the stove and set in cold water for about three minutes to cool it. When it is sufficiently cool to taste, a teaspoonful of a preparation of diastase is added, which renders the gruel thin and watery. This makes about a pint of gruel, con- taining the starches in soluble form, while the cellulose, or skeleton of the cereal, acts as a most effective attenu- ant of the curd. These digested gruels render the milk- curd porous, and also provoke the secretion of the digest- ive juices. As diluents, they are a great improvement on water. Most of the thick malt-extracts are sufficiently active in diastase to produce the desired effect." The writer, however, prefers the employment of diastase itself, without any of the other malt ingredients, as being both speedy and efficient. It can either be produced cheaply at home or purchased at the nearest drug-store. A simple decoction of diastase may be made as follows: A table- spoonful of malted barley-grains is put in a cup, and enough cold water added to cover it, usually two table- spoonfuls, as the malt quickly absorbs some of the water. This is prepared in the evening and placed in the re- frigerator over night. In the morning the water, looking like thin tea, is removed with a spoon or strained off, and is ready for use. About a tablespoonful of this solution DEXTRIXIZED GRUELS. 193 can be thus secured, and is very active in diastase. It is sufficient to dextrinize a pint of gruel in ten to fifteen minutes. Preparations of diastase are made by a number of chemists: Forbes; Parke, Davis & Co.; Horlick, and others. There is now obtainable an active glycerite of diastase known as cereo, which is specially made for the purpose of dextrinizing gruels. During the past summer, in those critical cases of sum- mer complaint in which subnormal digestion existed, the author has seen very good results follow the administra- tion of any and all of the malt-extracts now in our market. Frequently the administration of a teaspoonful of malt-extract to an infant immediately before feeding was not only relished by the infant on account of the pleasant taste of the malt, but certainly aided in the assimilation of the food. Rarely was more than 3 teaspoonfuls of malt ordered during twenty-four hours. Such preparations as maltine and also maltzyme gave very good results. The malt-extract of Parke, Davis & Co. has a very pleasant flavor and seems well borne. Frequently, when expense proved an important item, sufficient dextrinization of foods could be procured with these malt preparations above cited. It is claimed by some that most malt preparations de- teriorate on standing or if exposed too long; this is cer- tainly untrue. PART II. CHAPTER XXIX. Feeding of Infants in Incubators. "When we consider that the usual viability of a child is placed at twenty-eight weeks of intra-uterine gestation, then we can see how vastly different the method of feed- ing must be from that of a child born at term, or a so- called "full-born child." Method of Feeding. — The size of the child precludes the taking of an ordinary-sized nipple, and hence various measures have been tried, the most successful of which has been, according to the author's experience, feeding with a small medicine-dropper at intervals of two hours, the quantity varying with the age of the infant. It is a good plan, considering the capacity of the infant at term to be 1 ounce, to recognize the deficiency in the development of not only the size and capacity of the stomach, but also its lack of digestive function. Hence my plan has been to commence feeding by giving two teaspoon fuls of milk diluted with two teaspoonfuls of sugar-water; no lime-water and no salt added. A prematurely born baby is necessarily doomed with- out proper food, and there are so many other factors to be considered during its life in an incubator, such as its ventilation, its bodily warmth and cleanliness, that too much stress cannot be laid on the value of its food. With- out breast-milk, therefore, I feel justified in saying: I have yet to see the premature infant that will survive, and hence I advise procuring breast-milk, containing no colostrum-corpuscles, from a woman having a child any- (194) FEEDING OF INFANTS IN INCUBATORS. 195 where from two or three weeks to several months old, and diluting this breast-milk, as stated above, with a solution of cane- or milk- sugar. Voorhees 57 says: "Regarding the care of premature babies in incubators, we have relied mainly on diluted breast-milk, and have only employed cows' milk in weak proportions when it was impossible to obtain the former. In our opinion, our results would have been much poorer without the help of mothers' milk." In rare instances, where infants are very weak, and seem to doze and will not swallow, a No. 7-American Tiemann & Co. rubber catheter, having a velvet eye, can be attached to a long rubber tube about one foot in length and ending in a little funnel, holding several ounces. (See illustration, Fig. 40.) With this funnel and catheter forced feeding ■ — ■ so-called gavage — can be performed. With the infant lying flat on its back, push the catheter slowly, but forcibly, through the mouth as far against the pharynx as possible, and continue to push the tube from the pharynx into the oesophagus and the stomach. In all, from five to seven inches, rarely more, will be necessary to reach the stomach. The milk, properly di- luted with an equal quantity of milk-sugar solution, can then be allowed to flow into the stomach, and the cath- eter must then be very quickly withdrawn. Such feeding should be repeated once in four, five, or six hours, de- pending on the requirements of the case. Each infant is a law unto itself, and hence no cast-iron rule can be laid down, but each individual case should be studied sepa- rately and its requirements met as indicated. Thus I have found in a premature infant, born at seven months, that 6 drachms was enough for one feeding, and this was well borne once in three hours. The food consisted of equal parts of breast-milk and milk-sugar water. This feeding was continued for one week, when the child cried "Archives of Pediatrics, May, 1900. 196 INFANT-FEEDING. very much, and, on attempting to satisfy it, the infant swallowed 1 1 / 2 ounces. We then alternated each feeding by giving a large meal of 1 1 / 2 ounces followed by a small meal of 6 drachms, and fed in this manner every two hours until the child was three weeks old. We then gave 1 1 / 2 ounces of food every two hours. The child's stool was quite good; it soiled from two to three napkins every day, and, when it was very restless, we gave it from 2 to 3 teaspoonfuls of boiled water, which seemed to satisfy it. I would urge the necessity of giving plain, sterilized water freely to all infants living in an incubator. The increased temperature of its surroundings calls for it; so does also the necessity for eliminating through skin, bow- els, and kidneys. Dangers of Feeding. — Yery small quantities of food should be used in gavage — feedings of the mouth or when feeding through the nose. No more than 4 to 6 drachms should be used, and thus we can feel our way. It is a good point to remember that, the pharynx being very sensitive, the irritation of the tube in passing into the stomach may provoke regurgitation of some of this food, and frequently vomiting will be produced. In such in- stances, if the posterior nares or the pharynx is filled with food, the infant can easily suck some of this fluid during an inspiration into its trachea, and start up a pneu- monia in the same manner as is done by a child having a tube in the larynx in the treatment of laryngeal stenosis. Rectal feeding for premature infants is rarely called for, but it can and should be tried if the infant will not swallow and the forced feeding through the mouth or nose is unsuccessful. In such instances use very dilute milk, thoroughly peptonized, — the same proportions, however, as have been stated previously, namely: 1 / 2 milk and 1 / 2 water. The formula for rectal feeding should be: — TJ Breast-milk V 2 ounce. Starch-water 1 / 2 ounce. FEEDING OF INFANTS IN INCUBATORS. . 197 Add contents of 1 Fairchild peptonizing tube, and inject this quantity with an infant's rectal syringe. (See illustration, Fig. 41.) The starch-water is made by tak- ing 2 teaspoonfuls of ordinary starch and mixing it with 1 / 2 teacupful of warm water (not boiling water) and making a milky mixture of the same. This starch- water should be made fresh for each feeding. It is ad- visable to feed about once every six hours with the above solution. Cleanse the rectum thoroughly by washing with 1 / 2 pint of lukewarm, Castile-soap water to remove all fasces ten minutes before the nutrient fluid (peptonized milk) is injected. PREMATURE INFANTS (GRIFFITH). Premature Birth. — A child may be born in the sev- enth or eighth month of pregnancy, or even earlier, long before it is quite ready to live outside of the mother's body, and when it weighs not more, perhaps, than two and a half or three pounds. We need not necessarily despair of the life of a baby, however unpromising it seems at first. Children born at six and a half months have grown up strong at last, although it is not often they survive if born before the seventh month. The great need of such a baby is heat, and the maternity hos- pitals employ an apparatus, called a couveuse, brooder, or incubator, especially devised to supply it. (Fig. 38.) For family use, a couveuse may be bought at the instru- ment-makers, or hired from some of them. This is, per- haps, better, as the apparatus is costly. But with an increased degree of attention we may get along fairly well without it. If a premature baby is bathed at all after birth, the temperature of the water should be 102° F., and the greatest care should be taken, while drying, to see that the child is not chilled. It should be made very warm by swaddling it in raw cotton, head and all, leaving only the face exposed, wrapping it about with a 198 , INFANT-FEEDING. blanket, and tying it around with a roller bandage. Hot bottles should be placed on each side of it as it lies thus wrapped up in the bed, and fresh ones be substituted fre- quently. A. very convenient method is to place the child in a baby's bath-tub half-full of raw cotton in which numerous hot bottles have been concealed. The child's only clothing consists of a diaper and a shirt. The room should be kept warm, and especially so when this human bundle is unwrapped for its bath. After bathing, it should be rubbed with swxet oil and be rolled up again in fresh cotton. Often it is better to omit all bathing, and simply to rub with the oil. These premature infants lose considerably more in proportion to their birth-weight than babies at term. This is due to their immature digestive tract; also to the fact that they are almost invariably intensely jaundiced. They gain very slowly, and, if at the end of two or three weeks they have reached their birth-weight, they have done un- usually well. In some of the babies the color is poor from the be- ginning, and at any time they are especially liable to at- tacks of cyanosis. For these conditions a little slapping to cause a good cry or the administration of oxygen will dissipate the blueness. Often a few drops of brandy in hot water every two or three hours will prevent further trouble. One must be very sure, however, that nothing has been aspirated into the larynx. A great danger in the care of these babies is their susceptibility to infections. The incubator itself is a great germ-carrier, and should be regularly disinfected. The weakness of the lungs and gastro-enteric tract makes the infants especially vulnerable. Unless the air is fil- tered, dirt is carried in continuously; consequently the streptococcus, staphylococcus, and pneumococcus are al- ways present, seeking an avenue of entrance. Through the skin in eczematous spots or in areas of irritation; at the navel; through the eyes, nose, mouth, larynx, lungs, FEEDING OF INFANTS IN INCUBATORS. _ 199 stomach, and rectum the bacteria can gain admission. To prevent infection the most careful cleansing is always nec- essary, both of the incubator and the baby. Undoubtedly most of the deaths of our cases could be traced to this source. Finally, in the carrying out of the above essentials in the proper management of the' premature infant, we require the most patient and painstaking attention on the part of the nurse, and upon her conscientiousness depends the chance of its survival. Results. — The statistics are taken from 2314 births which occurred at the Sloane Maternity Hospital. Tour hundred and ten of these babies were prema- ture, but of these 74 were still-births, which include mac- erated foetus, and still-born babies of cases of placenta prsevia, accidental haemorrhage, eclampsia, and the like, leaving 336 for treatment. Among these cases were a set of triplets, and there were 18 pairs of twins; 85 were treated as infants at term, and of these 4 died, — a mortality of 4 1 / 2 per cent. ; 145 were put in cotton, and of these 12 died, — a mor- tality of 8 per cent. Some of this class should have been placed in the incubator, but for lack of room it was im- possible; 106 were incubator babies. These are divided into two classes: 1. Those that died within four days of birth. 2. Those that lived longer than four days. Twenty-nine of the incubator babies died within four days. All of these but 3 were more or less asphyxiated at birth ; 9 were breech cases, and of these 5 were difficult extractions; 3 after an accouchement force in placenta prsevia. The rest were vertex presentations, but of these 2 were forceps deliveries; 6 were under 7 months of uterine gestation; 22 were between 7 and 8 months along, and 1, 8 1 / 4 months. The etiology of the premature labor was an endo- metritis in 14; syphilis in 2; albuminuria in 1; placenta 200 INFANT-FEEDING. praevia in 3; accidental hemorrhage in 1; persistent vomiting in 1; twin in 1; violence in 1; and in 4 the labor was induced. The largest baby weighed 5 2 /ie pounds; the smallest 2 7 / 16 pounds. Only 5 infants lived over twenty-four hours; 24 were in such poor con- dition at birth that they survived only a few hours. In 16 autopsies were held, and in all of these there were marked atelectasis; in 7 haemorrhages of some degree, either into the brain or into the serous membranes; in 2 the foramen ovale was still patent. Seventy-seven incubator infants survived the first four days; 51 were children of primiparae, 27 of whom were out of wedlock; 3 infants were under 7 months of gestation, 8 were over 8 months along; 9 were breech presentations; 1 a transverse and the rest vertices; 2 were of triplets associated with albuminuria; 18 were in twin deliveries, associated with albuminuria or hydram- nios. The cause of the premature labor was endometritis in 27; syphilis in 4; phthisis in 2; albuminuria in 7; accidental haemorrhage in 1; placenta prsevia in 1; in 2 the labor was induced for albuminuria and eclampsia; 1 was a Caesarean section; another an ectopic gestation; the cause of the rest was unknown. Seven were delivered by forceps; 2 by a version; 1 by accouchement force; 1 by Caesarean section, and the ectopic gestation by a lapa- rotomy; 12 were slightly asphyxiated at birth; 9 mod- erately so, and 5 deeply asphyxiated; 2, after one and a half hours' work of resuscitation, were put in the in- cubator head downward, and their condition was so poor that they were expected soon to die, but they left the hospital gaining in weight; 5 weighed less than 3 pounds; 38 between 3 and 4 pounds; 33 between 4 and 5 pounds; 1 over 5 pounds; the average weight was 3 12 / 16 pounds. During their incubator-life 28 had one or more attacks of atelectasis. All but 10 were more or less jaundiced. The initial loss of the infants was from 1 to 17 1 / 2 ounces; the average was 7 ounces. These figures are not quite FEEDING OF INFANTS IN INCUBATORS. 201 correct, as the babies were weighed at different intervals, some on the fifth day, some on the seventh day, and others not till the fourteenth day. tSRl Fig. 38. 202 INFANT-FEEDING. The period of loss was from five to twenty-two days, the average, eleven days; 10 lost steadily till death; one baby was in the incubator only three days, while another lived there eighty-two days. The average time was nine- teen days. Some were removed early to make room for others who needed the place more urgently. Only 3 of the 77 cases vomited. The stools were normal in 32. One was discharged from the hospital as early as the eleventh day, and others also too soon at their mothers' demand. One was 89 days old; the average was 24 days. In 16 diluted breast-milk was supplemented, at times, with a mixture of cows' milk and water, with Russian gelatin and lactose. In 10 a 1, 6, 0.33 modification was used. In all the rest diluted breast-milk was relied upon. Twenty-seven never nursed at the breast; of these, 12 died. A few nursed as early as the third or fourth day two or three times a day. Others not for three weeks, and one not till the sixty-eighth day. Of the 77, 13 died in the hospital: a mortality of 16 per cent. The cause of death was atelectasis and bronchitis in 7, acute asphyxia from a curd in the larynx in 1, syphilitic pneumonia in 1, cerebral haemorrhage in 1, gastro-enteritis in 3, and a patent foramen ovale and ductus arteriosus in 1. The condition of 3 was poor at the time of discharge, fair in 24, and very good in 37; 32 were above their birth- weights, and 57 were gaining nr weight. To letters written about January 1, 1900, no answer was obtained from 28. Thirteen were reported as having died, 1 of these lived fourteen months, 1 nine months, 1 four and one-half months, 3 lived two months, 6 lived six weeks, 1 only a month. Five of these died at the Nursery and Child's Hospital and 2 died at Bellevue Hospital. They were bottle-fed, and the probable cause of death was gastro-enteritis. Twenty-one were found to be alive and doing well. Some had nursed and the others were bottle- fed. The oldest baby was twenty-two months, and al- FEEDING OF INFANTS IN INCUBATOES. 203 most all were good, healthy children. One baby at seven months weighed 16 pounds. It weighed 4 Vie pounds at birth, and nursed from its mother after leaving the hospital. The ectopic and the Csesarean babies were in beautiful condition. Incubators. Tarnier. Per Cent. Charles. Per Cent. Sloane Hospital Per Cent. At the Sloane Hospital, not Counting those which Died in a Few Hours. Per Cent. Saved at 6 months. Saved at 6J months. Saved at 7 months. Saved at 7J months. Saved at 8 months. 16 36 49 77 88 10 20 40 75 22 41 75 70 66 71 89 91 The incubator here described (see illustration, Fig. 38) is the one used at the Sloane Maternity Hospital. There are a great variety of these incubators, but the one made by the Kny-Scheerer Company in this city will an- swer all requirements. Owing to its expense, the manu- facturers will lend an incubator for a nominal sum per month. Food used in an incubator when breast-milk was not obtainable; baby gained in weight and took diluted cows' milk after five weeks. Of goat-milk, diluted with sterile water : — Goat-milk 1 part; Sterile water 4 parts ; Milk-sugar Va teaspoonful; Peptogenic y 4 measure, heated five minutes, 1 ounce was fed with a medicine- dropper to a premature baby every two and one-half hours, later every two hours, with excellent results. CHAPTER XXX. Aerated Milk. Aeration of Milk. — Milk when drawn from the cow contains a certain amount of dissolved gases. These gases contain more or less of what is known as animal odor, the amount of this odor depending very largely upon the physical condition of the animal at the time the milk is drawn. Sometimes the amount is very slight and scarcely noticeable; at other times it is so great as to be extremely offensive. These gases and the accompanying odor are easily removed from the milk by exposure of the milk to the air during the process of cooling, and to this extent aeration of the milk is an advantage. Various forms of aerators and combined aerators and coolers have been devised, many of which are simple and effective, and the best results follow their use. In order to secure these results by aeration, however, it is necessary that the ap- paratus used for aeration should expose the milk thor- oughly to the air, should not be cumbersome, and should be simple and easily cleaned; moreover, the process of aeration should always take place in the purest atmos- phere possible. Certified Milk. Dr. IT. L. Coit organized a medical commission in Newark, 1ST. J., which has made agreements with the dairymen compelling them to look after the details per- taining to the food, the selection of the cows, and — most particularly — the handling of the milk. All this is under the supervision of the Medical Commission. A veterinary surgeon is employed for the inspection of the animals. In like manner a chemist and bacteriologist see that the (204) CERTIFIED MILK. 205 milk is kept to the standard requirements of composition and purity. The milk is delivered in bottles, which are labeled "Certified Milk." This plan has proved to be very successful, and certainly deserves imitation. CHAPTER XXXI. Proprietary Infant-foods. There have been a great number of infant-foods and seemingly a great variety placed upon the market and ex- ploited by the makers as suitable for the artificial feeding of infants. These infant-foods may be broadly classified under two heads of (A) infant-foods in which cows' milk desic- cated is a constituent, and (B) infant-foods to be used with and as adjuncts to fresh cows' milk. Fig. 39. — Feeding-cup, after Period of Weaning. The infant-foods of which dried milk is a constituent are made from cereals and cows' milk. The milk is desic- cated in the process of manufacture, and these foods are commonly known as dried-milk foods, although in this class of foods milk-solids constitute but from one-eighth to one-fourth the substance of the foods, the balance con- sisting of matters derived from cereals. In some of these foods the starch of the cereals is untransformed, and they (206) PROPRIETARY INFANT-FOODS. 207 may be termed farinaceous dried-milk foods. In others the starch of the cereals has been transformed into dex- trin and maltose, and they may be termed malted dried- milk foods. All attempts to preserve whole cows' milk by evapo- rating it to dryness have been failures; the fat of desic- cated milk soon acquires a rancid flavor, and the caseous matter does not properly dissolve in water, as the drying process destroys its colloidal condition. In the dried- milk foods the caseous matter of the cows' milk is inti- mately mixed with the other ingredients, but its colloidal condition has been destroyed, and it is in the form of fine, hard, granular particles, very sparingly soluble in water. The group of infant-foods used as adjuncts to cows' milk are either farinaceous foods, made from cereals and consisting largely of unconverted starch ; or malted foods, also made from cereals, but having the starch transformed into soluble maltose and dextrin. As fresh cows' milk is, without doubt, the best generally available material for the artificial feeding of infants, the foods of the latter class, used for the modification of fresh cows' milk, are more in accord with physiological principles than are the dried-milk foods. Of the large number of infant-foods that have been put on the market, it is our purpose to describe a few commonly known foods. In order to judge fairly of the nutritive value of an infant-food and its resemblance to woman's milk, it is necessary to know its composition after its preparation for the nursing-bottle according to the directions of its manufacturer, and the analyses that accompany the following descriptions are of the foods prepared for use for infants six months of age as per directions on the packages. The published analyses of woman's milk show the great variability of its composition, especially as regards the percentages of proteids and fats. The analysis of woman's milk used in the following tables is by Dr. Luff, 208 INFANT-FEEDING. adopted as the standard by Cheadle. It agrees closely with Leeds's analysis, excepting as to the fat, which is given by Luff as 2.41 per cent, and by Leeds as 4.13 per cent.; the latter amount seems too large, as it exceeds considerably the published averages of a number of ob- servers. nestle' s FOOD. ISTestle's food is a farinaceous dried-milk food of Class A. According to the manufacturers, it is made "from the richest and purest cows' milk, the crust of wheaten bread, and cane-sugar," and is a "form of modified milk." "JSTo cows' milk is to be added to Nestle's food; nothing but water, and that water is boiled." Upon examination, unconverted starch and cane- sugar are found to be its principal constituents, amount- ing to about 70 per cent, of the whole. The directions for preparing Nestle's food for the nursing-bottle, for in- fants six months old, are to use 2 level tablespoonfuls of the food to 1 / 2 pint of water; mix the food with enough warm water to make a smooth paste that will pour, add the rest of the water and boil in a sauce-pan, stirring constantly until it thickens and a milky foam appears on the top. Composition of Nestle's Food,™ when Prepared as Above. Woman's Milk. Water 92.76 88.51 Salts 0.13 0.34 Proteids 0.81 2.35 Fat 0.36 2.41 Starch 1.99 Cane-sugar 2.57 Maltose, dextrin, etc 0.44 Milk-sugar 0.84 6.39 Reaction alkaline. Reaction alkaline. 1 According to Chittenden. PROPRIETARY INFANT-FOODS. 209 The mixture owes its thick condition mainly to the insoluble starch present. The total carbohydrates therein (5.84 per cent.) are somewhat less than the carbohydrate, milk-sugar (6.39 per cent.), in woman's milk; it is to be noted that of this amount 1.99 per cent., or about one- third, consists of insoluble starch. The fat is nearly one-sixth and the proteids are about one-third of the amounts in woman's milk, and over one- half of the proteids is insoluble, owing to the colloidal condition of the milk-casein having been destroyed by drying during manufacture. horlick's malted milk. This is a malted dried-milk food of Class A, stated on the circulars to be composed of pure, rich, cows' milk combined with an extract of malted grain, and not to re- quire the addition of cows' milk. Its makers claim that, by special treatment with their new agent, plant-pepsin, the casein, or cheesy part, of the cows' milk is kept from forming large and irritating curds in the stomach. The directions for preparing the food for an infant six to twelve months of age are to dissolve 4 to 6 tea- spoonfuls in V2 P int of water. Composition when pre- pared by using 6 teaspoonfuls of food to 1 / 2 pint of water : — Horlick's Malted Milk. m Woman's Milk. Water 92.47 88.51 Salts 0-29 0- 34 Proteids L15 2 - 35 Fat °.68 2Al Maltose and dextrin 4.20 Milk-sugar I- 18 6 - 39 Reaction alkaline. Reaction alkaline. This food is very nearly soluble in water, as its prin- cipal constituents are the soluble carbohydrates— maltose, 69 According to Chittenden. 210 INFANT-FEEDING. dextrin, and milk-sugar: The drying process lias de- stroyed the colloidal condition of the caseous matter of the milk, and it is in the form of finely powdered, hard particles, sparingly soluble in water. The proteids, fat, and carbohydrates are all less than in woman's milk, the proteids being not quite one-half and the fat not quite one-third of the amounts in woman's milk. The amount of milk employed must be very small in proportion to the cereal constituents, since the mixture, prepared as above, corresponds to a dilution of 1 part of good cows' milk with about 4 parts of water. MILKINE. This is a malted dried-milk food (Class A). Its mak- ers state it is a complete food ready for immediate use by the addition of water, and the only prepared food that combines the nutritive elements of meat, milk, and cereals. In this malted dried-milk food, beef-extract is com- bined with cereal extractives and dried milk. Soluble car- bohydrates are its principal constituents, forming nearly three-fourths of the product. The proteids are sparingly soluble. The directions for preparing milkine for an infant three to six months of age are to dissolve 1 to 2 dessert- spoonfuls of food in a breakfastcupful of water. Composition when prepared with 2 dessertspoonfuls in a breakfastcupful of water: — Milkine. Woman's Milk. Water 92.78 88.51 Salts 0.23 0.34 Proteids 0.92 2.35 Fat 0.43 2.41 Maltose, dextrin, etc 4.74 Milk-sugar 0.90 6.39 Reaction alkaline. Reaction alkaline. The total solids are hardly two-thirds of the amount in woman's milk. The fat especially is greatly deficient, PROPRIETARY INFANT-FOODS. 211 being only about one-sixth of the amount in woman's milk, and the proteids are but two-fifths of the amount in woman's milk. A dilution of 1 part of good cows' milk with about 7 parts of water will contain about the same amount of milk as milkine prepared as above. CEREAL MILK. Cereal milk is a malted dried-milk food (Class A). It is stated by its makers to be a complete food, cooked and ready for use with the simple addition of water, and to be made from the purest Vermont dairy-milk, the finest wheat-gluten flour, the best barley-malt, and milk-sugar. Cereal milk in general appearance very much resem- bles the other malted dried-milk foods, but it contains a much greater percentage of milk-sugar, showing that this substance is used in its manufacture, as claimed. The directions for preparing it for use are to mix 1 teaspoonful of cereal milk in a teacupful of hot water for infants under three months of age or for a very deli- cate child. For older and stronger children 1 to 2 tea- spoonfuls of food are to be used to each cupful of water. Composition when prepared by using 2 heaping teaspoon- fuls of food to a teacupful of water: — Cereal Milk. Woman's Milk. Water 92.52 88.51 Salts 0.16 0.34 Proteids 0.69 2.35 Tat 0.30 2.41 Maltose, dextrin, etc 4.73 Milk-sugar 1.60 6.39 Eeaction alkaline. Reaction alkaline. The total of soluble carbohydrates as above is prac- tically the same as in woman's milk; the amount of pro- teids is less than one-third the amount in woman's milk, and about one-half is insoluble in water. The amount of fat is one-eighth the amount in woman's milk. The small 212 INFANT-FEEDING. amount of fat indicates that the cereal extractives and milk-sugar make up the bulk of the solids of this food, and that a dilution of 1 part of good cows' milk with 11 parts of water would be the counterpart of the above mixture as to the amount of milk therein. wampole's milk-food. Wampole's milk-food is a malted dried-milk food (Class A). Its makers state that it is made from malted cereals, beef, and milk, and when mixed with warm water it is immediately ready for use; no other preparation necessary. This dried-milk food is very nearly soluble in water, owing to the soluble carbohydrates being so large a con- stituent. A little less than one-half of the proteids is insoluble in water. A small amount of beef-extract has been combined with the cereal extractives and dried milk. To prepare it for an infant six months to one year of age, the directions are to dissolve 4 to 6 teaspoonfuls of the food in 6 ounces of hot water. Composition when prepared by dissolving 6 teaspoonfuls in 6 ounces of water: — Wampole's Milk-food. Woman's Milk. Water 88.59 88.51 Salts 0.46 0.34 Proteids 1.58 2.35 Fat 0.73 2.41 Maltose, dextrin, etc . 7.65 Milk-sugar 0.99 6.39 Reaction alkaline. Reaction alkaline. Compared with woman's milk it is seen that the car- bohydrates are considerably in excess, and the proteids and fat are deficient, the fat especially, it being less than one-third the amount in woman's milk. One part of good cows' milk diluted with about 3 1 / 2 parts of water would be analogous to the dilution of milk in "Wampole's milk-food prepared as above. PROPRIETARY INFANT-FOODS. 213 IMPERIAL GRANUM. Imperial granum is a farinaceous food to be used as an adjunct to cows' milk (Class B). Its makers state that it is a solid extract derived from very superior growths of wheat, nothing more. It appears to be made as claimed from wheaten flour and to be mainly composed of torrefied starch. Tor an infant six months of age it is to be prepared by cooking 3 1 / 2 teaspoonfuls of food in 21 ounces of water and 20 ounces of milk. Composition when prepared as above: — Imperial Granum. 00 Woman's Milk. Water 91.53 88.51 Salts 0.34 0.34 Proteids 2.15 2.35 Fat 1-54 2.41 Starch 1.22 Maltose, dextrin, etc 0.58 Milk-sugar 2.71 6.39 Reaction alkaline. Reaction alkaline. The total of solids contained is one-quarter less than in woman's milk; the carbohydrates are nearly one-third less than the amount in woman's milk and it should be observed that 1.22 per cent., or about one-fourth of them, consist of starch; there is only a slight deficiency in the amount of proteids, but a considerable deficiency in the amount of fat. By using more milk or milk and cream and less water than above employed the percentages of fat, proteids, and soluble carbohydrates would be in- creased. Its very large proportion of starch forms the principal objection to this food. The presence of unconverted starch causes the thick condition of the mixture. 80 According to Chittenden. 214 INFANT-FEEDING. eskay's ALBUMENIZED FOOD. This food is to be prepared with cows' milk (Class B). Its makers state, in recommending their product, that it contains the more easily digested cereals, combined with egg-albumin. Eskay's albumenized food consists largely (about 88 per cent.) of carbohydrates; the soluble carbohydrates, mostly milk-sugar, are about 50 per cent., and the insol- uble carbohydrates, mostly starch, are a little less than 40 per cent. On account of this proportion of starchy matter in the dry food, it may be termed farinaceous. The mak- ers, however, claim that in the process of manufacture the starch-granules are almost entirely disintegrated, and when the food is prepared with milk according to directions the percentage is said to be not over 1 1 / 2 to 2 per cent. An analysis of the dry food shows that it contains about 9 per cent, of proteid matter, but when prepared accord- ing to the six months' formula it analyzes about 2.55 per cent. The egg-albumin is said to be first combined with sugar of milk in such a thorough manner that the parti- cles are finely subdivided, and no firm, hard coagulum can therefore take place in the stomach. The particles retain their identity, and do not coalesce; so that in the finished preparation the egg-albumin is suspended throughout the whole mixture in very fine particles, which are easily di- gested, because the gastric juice acts by contact, and, the smaller the particles, the greater the effect of the gastric juice. No claims are made by the manufacturers for its solubility, but for its ease of digestion and its nutritive, value. The directions for preparing it for an infant six months of age are to take: — 2y 2 tablespoonfuls of food. 1 pint of hot water. 1 pint of rich cows' milk. PROPRIETARY INFANT-FOODS. 215 When prepared as above, using rich cows' milk, con- taining about 6 per cent, of fat, their analysis shows that it contains: — Eskay's Albumenizcd Food. Woman's Milk. Fat 2.96 2.41 Proteids 2.55 2.35 Carbohydrates 6.13 6.39 Milk-sugar 5.07 Insoluble carbohydrates 1.06 Reaction alkaline. Reaction alkaline. mellin's FOOD. Mellin's food is a malted cereal food (Class B). This food is stated by its makers to be a soluble dry extract from wheat and malt, for the modification of fresh cows' milk. The carbohydrates therein are in the form of dextrin and maltose, and constitute about 80 per cent, of the food; the proteids amount to about 10 per cent., and are derived from the cereals. Mellin's food is almost completely sol- uble in water. It is especially noticeable that this food does not contain any starch. The directions for preparing this food for use for in- fants six months of age and over are to dissolve 2 heaping tablespoonfuls of food in 1 / 4 pint of hot water and 3 / 4 pint of cows' milk. Composition when prepared as above: — Mellin's Food. 81 Woman's Millc. Water 88.00 88.51 Salts 0.47 0.34 Proteids 2.62 2.35 Pat 2.89 2.41 Maltose, dextrin, etc 2.73 Milk-sugar 3.25 6.39 Reaction alkaline. Reaction alkaline. According to Chittenden. 21G INFANT-FEEDING. In total solids this food differs but slightly from woman's milk, and in the various constituents its simili- tude to woman's milk is remarkably close. Of the car- bohydrates the maltose and dextrin are a little less in amount than the milk-sugar, and the total carbohydrates (5.98 per cent.) are only slightly less than the amount in woman's milk. The manufacturers of Mellin's food present many formulas for preparing the food for use to meet various indications. The following formulas are given with the analyses of the respective milk-modifications: — Formulae and Analyses for Preparing Mellin's Food. For Infants about Tioo Months Old. Mellin's food, 6 teaspoon- fuls (level). Milk, 6y 3 fluidounces. Water, 9% fluidounces. Gives this composition : f Water 93.40 Salts 0.35 Proteids 1.69 Fat 1.53 Carbohydrates (no starch) 3.03 Low Proteids. Mellin's food, 2 table- 1 spoonfuls (heaping). Cream, 1% tablespoon fuls. Milk, 4 fluidounces. Water, 12 fluidounces. Gives this composition: f Water 91.50 Salts 0.37 Proteids 1.45 Fat 2.50 Carbohydrates (no starch) 4.18 High Fat and Low Proteids. Mellin's food, 3 table- spoonfuls (heaping.) Milk, 4 fluidounces. Cream, 2 tablespoonfuls. Water, 12 fluidounces. Gives this composition: f Water 89.36 Salts 0.45 Proteids 1.65 Fat 3.00 Carbohydrates (no starch) 5.54 PROPRIETARY INFANT-FOODS. - 217 PEPTOGENIC MILK-POWDER. This product is stated by its makers to be an article containing milk-sugar and a digestive ferment capable of acting on casein, offered for the preparation of an arti- ficial infant-food. McGill states : "It is not, in the strict sense, a food. Its professed object is so to change the composition of cows' milk as to render this comparable to human milk. This it seeks to do by introducing milk- sugar and small quantities of albuminoids." According to McGill's analysis, it is composed almost entirely of milk-sugar (96.60 per cent.). The following analysis is by Leeds, and is taken from a circular of the makers. Composition of "humanized milk" prepared as di- rected, using 4 measures of peptogenic milk-powder with x / 2 pint of milk, 1 / 2 pint of water, and 4 tablespoonfuls of cream: — - Humanized Milk. Woman's Millc. Water 86.20 88.51 Ash 0.30 0.34 Proteids 2.00 2.35 Fat 4.50 2.41 Milk-sugar 7.00 6.39 Reaction alkaline. Reaction alkaline. Chittenden's analysis -of this "humanized milk" is al- most identical with the above. The proteids of the cows' milk undergo a change in the peptonizing process, being converted chiefly into par- tial peptones, and in this form they cannot be said to re- semble the proteids of woman's milk, which have not been acted upon by a proteolytic ferment. CHAPTER XXXII. Pbofessob Gaebtnee Mothee-milk. ' Seveeal years ago the author was persuaded to use Gaertner milk ou a series of cases. The milk was sold in tin cans. The manufacturers would not take the ad- vice given them: to use fresh milk and deliver the milk in clean bottles daily. The author feels sorry to state that such food as "milk sealed in tin cans" cannot be recommended for healthy, and certainly not for sick, in- fants. In a paper entitled "The Clinical Value and Chem- ical Results" the author published a paper in the Med- ical Record, December 11, 1897. This new food has now been used about five years in Europe, and is the outcome of the scientific endeavors of Professor Gaertner, of the University of Vienna. The first paper was published by Gaertner in the Therapeutische Wochenschrift, May 5, 1895. A few months before, January, 1895, Gaertner, in an address before the Vienna Scientific Society, explained the mode of preparation and the results obtained with his new modification of cows' milk, for such the mother- milk of Gaertner really is. Professor Gaertner, in the preparation of his food, has aimed to overcome what has been the great difficulty in infant-feeding — namely: to reduce the excess of casein by a scientific process without the addition of chemicals. To achieve this result he employs a machine called a separator or Pfannhaiiser centrifuge, which makes four thousand or eight thousand revolutions per minute. The apparatus consists essentially of a drum of steel, which revolves on its axis. This drum is filled with equal parts (218) GAERTNER MOTHER-MILK. 219 of fresh cows' milk and sterilized water. The mixture contains approximately the same amount of casein as hu- man milk, for cows' milk undiluted contains about twice as much casein as human milk. The mixture is next poured into the centrifuge and the speed of the drum is carefully regulated, so as to separate the mixture contained therein into (1) a creamy (fatty) milk and (2) a skimmed milk. The two portions so separated are then led off separately by suitable openings in the centrifuge. The analysis of each of these portions shows that the creamy milk has the same quantity of fat as is found in human milk, while about 2 per cent, of the casein is con- tained in the skim-milk, and the remainder, about 1.7 per cent., remains in the creamy milk. The chemical com- position of fat milk is shown in the following table: — Proteid. Fat. Sugar. Ash. Fat milk 1.76 3-3.5 2.5 0.35 Human milk 1.03 3.5 7.03 0.21 Cows' milk diluted with one- half water 1.76 1.6 2.5 0.35 If, now, 3 or 4 grammes of milk-sugar be added to every 100 cubic centimetres of fat milk, the percentage of sugar is brought up to the level of sugar in human milk. This addition is made before sterilizing. The fat milk has the advantage over the diluted milk of having "a higher percentage of fat"; it also curdles more slowly than diluted milk and the curd forms a more flocculerit precipitate. According to Escherich, the following amounts should be used at different ages of infancy, feeding every two to four hours: — Infants under 2 weeks 500 c.cms. (i7y 2 I) in 9 feedings Infants 3 to 4 weeks . 750 c.cms. (26 I) in 8 feedings Infants 4 to 8 weeks . . . 1,000 c.cms. (35 5) in 8 feedings Infants 3 to 4 months . . 1,250 c.cms. (42 5) in 8 feedings Infants 5 to 6 months . . 1,500 c.cms. (50 5) in 7 feedings 220 INFANT-FEEDING. Esclierich gives in detail his experience in feeding with fat milk fifty infants in a hospital, including rickety- and tuberculous children. He has certainly met with marked success. Some cases have been under observation for six months. His article is published in extenso in Mitteilungen des Vereins der Aerzie in Steiermarh, ~No. 1, 1895. Baginsky 62 mentions Gaertner milk as a new form of food introduced. In our country Jacobi 63 states that Gaertner milk is applicable to the majority of infants who require cows' milk appropriately prepared. A few years ago I proposed to test the efficacy of Gaertner milk. With this in view I subjected the milk to a very rigid test, inasmuch as the time chosen, from June to October, was the heated term, which is the worst for milk digestion, and the hygienic conditions of the infants were those found in the average tenement-house, too well known to need description. The guides for ascertaining the degree of assimilation were the following factors: — 1. The child's general condition, as manifested by its appearance, appetite, and sleep. 2. The presence or absence of gastro-enteric disturb- ances, such as vomiting, colic, restlessness. 3. The condition of the stools, constipation or diar- rhoea, the number of stools in twenty-four hours. 4. The gain in weight; weekly observations. The nurses or mothers were instructed to note the amount of food taken and the number of stools in twenty- four hours. We submitted the stools passed in twenty-four hours to Mr. Herman Poole, our chemist, whose chemical re- 62 "Lehrbueh der Kinderkrankheiten," fifth edition, pages 35 and 36. 63 "Therapeutics of Infancy and Childhood," page 508. BACKHAULS MILK. 221 port is of interest. 64 We tried to ascertain how much proteids, fat, sugar, and salts were taken, how much absorbed, and how much was voided in the faeces with- out having taken part in metabolism. Backhaus's Milk. 65 . The following method is employed in the production of this food. The milk from different breeds of cows is mixed and passed through a centrifuge, to separate the cream from the milk and to remove any impurities that might have gained access to the milk, notwithstanding the great care used in handling. Three grades are pro- duced: two for infants, the third representing full milk in its composition. After separating it from the cream the milk is exposed to the action of a mixture of rennet, trypsin, and sodium carbonate, which are combined in such proportions that the trypsin will have converted at the end of thirty minutes 30 per cent, of the casein into soluble albumin. By this time the action of the rennet coagulates the balance of the casein and thus arrests the action of the trypsin. The temperature of the mixture is now raised to 80° C. (176° F.) by the introduction of steam into it. At this temperature it is kept for five minutes. At the end of this time it is strained through cloths and mixed with half its volume of water, one- fourth its volume of cream, and the necessary amount of sugar of milk. It is finally put up in bottles holding 125 grammes (about 4 ounces) and sterilized. The second grade, for older children, is obtained by mixing equal parts of milk and water with half the quan- tity of cream and with milk-sugar. This is put up in quantities of 200 grammes (about 6 1 / 2 ounces). 64 Those interested are referred to my paper, entitled "Gaertner Milk," containing an elaborate chemical report by Professor Poole: New York Medical Record, December 11, 1897. G5 Archiv fur Kinderheilkunde, B. 26, H. 5 and 6. 222 INFANT-FEEDING. The third grade, in bottles holding 300 grammes (about 10 ounces), represents cows' milk in composition, modified by the above-mentioned process. The composi- tion of the three grades is given as follows: — Fat 3.1 3.2 3.3 Sugar of milk 6.0 5.4 4.8 Casein 0.6 1.8 3.0 , Albumin 1.0 0.3 0.5 Ash 0.4 0.4 0.7 The milk has been tried at the Wiener allgemeine Poliklinik by Friihwald in a series of twenty cases, the histories of which are given by the author. With the ex- ception of six, these children have been under observation for more than two months. When first seen the children were all suffering from different forms of digestive dis- turbances, and from malnutrition; some were suffering from severe marasmus, and. most of them passed through some other disease while they were under observation. Three of the infants took the breast in addition to the Backhaus milk for periods of two and three weeks, when they, too, had to be put on the artificial milk entirely. The children took about six bottles of ]STo. 1 up to four weeks, seven to eight to the end of the second month. From the middle of the third month the second degree was gradually substituted, while No. 3 was used only in the case of an older child. A daily gain was observed of from 18 to 30 grammes (about V 2 to 1 ounce). In private practice and in healthy children a gain of 50 grammes (about 1 1 / 2 ounces) not rarely happens. The milk keeps well. Lahmann's Vegetable-milk. In Europe, and recently also in our country, the feed- ing of infants has been enriched with a new product; thus, Dr. Lahmann believes that the great panacea is feeding infants with milk which he designates as "vege- lahmann's vegetable-milk. 223 table-milk." It resembles a thick jelly, and is made by Hewwel & Veithen, Cologne. His theory consists, in brief, in substituting nuts and almonds, which are rich in albumin and fat, instead of cereals to dilute milk, his idea being that an emulsion, which is digestible and sup- posed to be rich in albumin, is doubtless better than pure water or a thin starch-paste. In order to add food-salts, which are not supplied by this means, he extracted them from leaf vegetables, which are rich in food-salts, and added some sugar-syrup. In this manner he claims to have made a preparation which he states is chemically equal to human milk, and full of nutritive value. His idea is that the interposition of plant-albumin (conglutin) particles, which coagulate with difficulty between the coagulating casein masses, would increase their digesti- bility by breaking them up, and that the digestion of the plant-albumin and oil, as well as of the sugar and food- salts, would present no difficulty. Stutzer, of the University of Bonn, reports thus: The vegetable-milk is distinguished from children's food by the absence of starchy substances. In common with Biedert's cream-mixture, the vegetable-milk contains con- siderable quantities of fat in an emulsified condition. It differs from the cream-mixture in the way it is prepared, and in its other qualities. Chemical Analysis. Fat 34.72 per cent. Plant-casein and similar nitrogenous con- stituents 12.00 per cent. Sugar and plant-dextrin 31.02 per cent. Salts 1.64 per cent. Water 20.62 per cent. My own personal experience has been rather favor- able with the use of the vegetable-milk, inasmuch as an emulsion of almonds and nuts was used to dilute the curd of cows' milk. Thus, equal parts of vegetable-milk with 224 INFANT-FEEDING. cows' milk were taken by an infant for several months, and it was very well assimilated. Not only did the child gain in weight, bnt the bowels were in a fair condition, and the infant remained strong. My experience, how- ever, is too limited as yet to give a positive opinion. Condensed Milk ok Condensed Cream. Hundreds of infants are fed with condensed milk. This has its reason: — First. The readiness with which condensed milk is obtained. Second. The great cheapness of this article. Third. The ease with which the feeding-mixture can be prepared. Jacobi says that some manufacturers use pure cows' milk ; others find it in accordance with the health of their bank-accounts to use skimmed milk. Quantity of Sugar in Condensed Milk. — Milk sold in our city for immediate use contains about 12 to 15 per cent, of sugar. Milk to be kept for an indefinite time contains as much as 50 per cent, of sugar. These varia- tions show how serious it is to use the same quantity of condensed milk all the time and from different sources with such an enormous variation in the quantity of sugar. Kehrer — quoted by Jacobi — states, regarding it, that it increases the formation of lactic acid. Fleischman states that it gives rise to thrush and diarrhoea; Daly, that it fattens them (?), but gives rise to rachitis. The worst specimens of rachitis and spinal rickets are seen in my clinic in condensed-milk babies. Our medical literature reports many cases of apparent health in infants fed on condensed milk. It has led Dessau, with a large experience with infants, to mention such a method, al- CONDENSED MILK OR CONDENSED CREAM. 225 though he advocates cows' milk, properly modified, for continued use. 66 In traveling, when good fresh cows' milk cannot be obtained, then I permit the use of condensed milk, but for a few days or for a week only, as on the ocean steamer, where cows' milk cannot be had. My experience among hundreds of children seen in my Children's Service at the German Poliklinik and also at the service at the West-Side German Dispensary dur- ing these last ten years has been that children so fed have rickets; that they are predisposed to the infectious dis- orders; that they have less resistance and far less vitality, especially in combating such diseases as pneumonia or diphtheria; that they have tendencies to hernias and de- formities, owing to the softer condition of their muscles and bones; that they invariably suffer with constipation, alternating with diarrhoea; that their dentition is delayed, compared with other methods of hand-feeding. Thus summing it up, I cannot approve of this method at all. Condensed cream will be lauded by the mother whose baby is well, and again the same food will be con- demned by the mother of an infant whose rickety head, bones, and muscles are founded on an impoverished diet of condensed milk. We can account for the rickety child, but we cannot account for the healthy one on the same food. The directions on the tin of the Anglo-Swiss Con- densed Milk Company's Milkmaid Brand of condensed milk are, for newborn infants, add 14 parts of water; as the child grows older, gradually use less water, but never less than 7 parts. The analyses of all these condensed milks are of the milk diluted with both 7 parts and 14 parts of water — the two extremes. 66 See my paper on infant-feeding (read before the Society for Medical Progress, April 11, 1896), published in extenso in Pediatrics for July 15, 1896. 226 INFANT-FEEDING. Gail-Borden Eagle Milkmaid Brand. Brand. With 7 Parts With 14 Parts With 7 Parts With 14 Parts Water. Water. Water. Water. Water 88.18 93.59 89.10 94.09 Ash 0.36 0.19 0.29 0.16 Proteids 1.50 0.82 1.31 0.71 Fat 1.70 0.92 1.18 0.64 Cane-sugar 6.00 3.25 6.59 3.57 Milk-sugar 2.26 1.23 1.53 0.83 Nestle's Swiss Milk. Wi Wa 7 te ? r artS Wi Water. artS Woman's Milk. Water 87.95 93.46 88.51 Ash 0.25 0.14 0.34 Proteids 1.51 0.82 2.35 Fat 2.14 1.16 2.41 Cane-sugar 5.81 3.15 Milk-sugar 2.34 1.27 6.39 The foregoing brands of condensed milks are consid- ered to be among the best upon the market. Cocoa. Dr. H. Cohn, 67 in describing the chemical value of cocoa as nourishment, states his belief that it is over- rated, and denies the value of the same. He bases his statement on the poor method of assimilation, owing to the large quantity of fat which could be removed by chemical process. Cocoa also contains 5.5 per cent, of tannic acid. Besides, the albuminoids are converted, by the process of roasting, into a very indigestible product. About the tannic acid, he says that it precipitates the digestive ferments, and unites with the albuminoids into insoluble compounds, causing the constipating factor. According to his experiments, only one-half of the 16.6 per cent, of the albuminoids are absorbed, and, in order to give the human body enough cocoa to have a sufficient quantity of proteids, it would be necessary to feed at least Zeitschrift fur physiologische Chemie, xx, 1, 2. CHOCOLATE, ICE-CREAM, AND WATER-ICES. 227 somewhat over 2 pounds daily, provided cocoa alone was given for nourishment. « Chocolate. Chocolate contains about 45 per cent, of cane-sugar, but no dextrose or lsevulose. The remainder consists of cocoa-powder. Invert-sugar, or a mixture of glucose and albumin, is largely used in the preparation of uncrystal- lized sweets, such as the creamy matter in the interior of chocolate drops. The coloring of sweets is derived either from burnt sugar or from one of the aniline dyes, most commonly eosin. Cochineal is also a favorite colorer. It is interesting to know that these dyes may be excreted in the urine almost unchanged, and cases are on record where patients were supposed to be passing blood when they had merely been sucking red sweets. There is no reason to suppose, however, that such substances are harm- ful to life. 68 When there is a tendency to loose bowels, especially after the second summer, cocoa and chocolate should be added to the dietary. It is to be added to milk and thoroughly boiled. One cocoa feeding per day is usually enough. One teaspoonful of cocoa to a cup of milk, the latter to be thoroughly boiled, is the usual quan- tity used. Several formulae for making chocolate will be found in the "Dietary." Ice-cream and Water-ices. Ice-cream and water-ices are very grateful to a fever- ish child. When milk and cream are refused they will be greedily taken. These preparations will alleviate the pain on swallowing in the case of diphtheria. They contain considerable nourishment, but must be given in moderation. ISTausea and vomiting may frequently be controlled by them. 68 Hutchison, "Food and Dietetics/' page 265. CHAPTEK XXXIII. Milk Idiosyncrasies in Children. Some children will not tolerate milk; physicians fre- quently report an intolerance of milk or its dilutions in children. This condition has long been known among adults. We frequently hear the latter say that milk makes them bilious, that it is not tolerated, and that they feel uncomfortable after a milk diet. While this condition is of much rarer occurrence in children, certain cases are met in which milk is not tolerated. It has been the milk itself or the component parts of the same that has dis- agreed in certain children under the treatment of the writer. Breast-milk and several changes of wet-nurses gave the same distressing symptoms. Cows' milk was not tolerated, and was discontinued after various dilutions had been tried. The following case will serve to illustrate what is meant by the above condition: — Case /.—An infant, M. L., was born in July, 1901. The weight at birth was about 6 pounds. The mother had no milk, so a wet- nurse was secured. The infant was thus nursed for the next three months. The child gained about 8 ounces per week during the month of July, but in August and September it did not thrive. History of food after weaning: When the child was weaned, in October, it was given condensed milk, 1 drachm, to 12 drachms of sterile water, to which 1 drachm of lime-water was added. The child vomited and had eructations, although it had from one to two yellowish stools per day. When this child was weaned it was al- ways constipated and required an enema of plain water to relieve the bowel. The stools during the summer months contained a great deal of mucus, which was shredded and yelloAvish green in color. The infant was colicky; the stools had a very sour smell; the child frequently had an explosive vomit. The condensed milk was continued through the month of October, and, as the child did not seem to thrive, it was given Just's food. This the child re- (228) MILK IDIOSYNCRASIES IN CHILDREN. 229 fused, so Nestle's food was substituted and seemed to agree. When milk was added the child vomited a sour-smelling liquid, and later on refused the Nestle's food. As there was constant anorexia, the child was next fed with Ridge's food. As this was not very well borne, a trial was made of Allenbury's food. When this dis- agreed, the child was placed on Eskay's albumenized food. This also was not tolerated, and the child was given some strengthening meal. This was not borne any better. Examination: On November 24th the child weighed about 9 pounds. It had lost 8 ounces the week previous to its parents consulting me. This loss of weight disturbed the family and caused them to seek a change of diet. The examination of the child showed some very interesting facts. First, the general appearance of the child was one of an undersized, undeveloped, markedly ra- chitic baby; there were beaded ribs; the ends of the long bones— particularly the radius, ulna, and femur — were markedly rachitic. Subluxation of the knee-joints was present. The head of the child was very rachitic; the fontanelle was very widely open; in fact, the fontanelle was three times the size of that of a normal baby. The extremities were extremely cold; the circulation was very poor; the action of the heart was very feeble; a blowing murmur was distinctly heard at the apex and could also be heard in the vessels of the neck. It was a distinct hsemic murmur, and was attributed to the profound anaemic condition which was found to exist. The trained nurse in charge of the case had been with the baby since birth and had stated that the child had had a series of spasms which were not only regular, clonic, and tonic contractions, but they occurred once every twenty-four hours at a certain time of the day. The child was very fretful, very nervous, constantly irritable, and had had very restless spells at night, which disturbed its sleep. There was a slight eruption around the anus; the child had difficulty in taking the nipples as well as nursing at the breast. An examination of the throat showed congenital adenoid vege- tations. This latter condition interfered with the child's proper feeding; it prevented the child from properly taking its food and breathing at the same time. It would take the nipple or the breast and then let go, in order to breathe. Spoon feeding was resorted to when the child would not take food from its bottle. Attention was directed to the rhino-pharynx. By gradual cauter- ization the child's condition was so markedly improved that its general condition, with the appetite, stools, sleep, and weight, all assumed normal tendencies. 230 INFANT-FEEDING. Dietetic treatment: The child was given the following: — IJ. Whey 2 ounces. Milk 2% ounces. Peptogenic powder .... % measure of the metal cap. Granulated sugar y 2 teaspoonful. Mix the above and peptonize the milk by a slow process for about ten minutes, and when cooled to the proper feeding tempera- ture feed the above quantity every three hours. The child took the bottle very well; in fact, took 4 ounces, re- tained the food, and seemed to like it. The following are the nurse's reports: — "November 24th, 10.30 p.m., took 4 ounces; has not vomited; seems to like food." "November 25th, 4 a.m., took 4 % ounces of food ; retained, at 7 a.m. took nearly 4 ounces; retained. At 11 a.m. child crying and abdomen distended; child appears colicky." A warm enema consisting of 2 pints of chamomile-tea was ordered; so that the colon and rectum were thoroughly flushed. The child was instantly relieved after some cheesy curds and mucus, plus fseces, were washed away. These fermentative conditions — resulting in gaseous eructations; colicky, distended, tense abdomen, with crying and occasional cheesy, curdy stools, the temperature frequently reaching 101° to 103° F. in the rectum, occasional vomit- ing, and disturbed appetite — were invariably noticed when milk, peptonized or predigested or in any form, was given to this child. It was therefore apparent to me that this baby would not digest milk, and hence some other form of feeding was required. On December 17th a new form of feeding was commenced which is known as a modified form of malt-soup. A similar plan of feed- ing is used extensively abroad, at the foundling asylums which I visited; notably at the New Berlin Foundling Asylum, which is under the supervision of Dr. Finkeistein. This food is known as Kellwr's malt-soup. Its preparation is rather difficult unless per- formed by a competent chemist. This food has been used for many years in the nursling pavilion of the Kaiser and Kaiserin Friedrich Children's Hospital, under the direction of Professor Baginsky. I am indebted to the New York Walker-Gordon Laboratory for great care in the preparation of this food, which has certainly served me very well. The following formula was used in the beginning and was changed, as can be seen by studying the accompanying table: — MILK IDIOSYNCRASIES IN CHILDREN. 231 Food Ordered at Walker-Gordon Laboratory. (Delivered daily as ordered for Case 1.) Dec. 20 1901. Dec. 24 1901 . Jan. 4 1902 . Jan. 9» 1902 . Jan. 12. 1902 . . Jan. 21, 1902 . . Feb. 7, 1902 . . Feb. 18, 1902 . . Feb. 22, 1902 . . Mar. 1, 1902 . . Mar. 3, 1902 . . Mar. 6, 1902 . . Mar. 10, 1902 . . Mar. 17, 1902 . . April April April April April April May 1, 13, 16, 18, 22, 2(i, 2, 1902 . . 1902 . . 1902 . . 1902 . . 1902 . . 1902 . . 1902 . . May- 21, 1902. . May 23, 1902 . . NO. OF Oz. TUBES. 4 3 4 3 8 3 8 Wo 8 4 5 4 8 4 4 4 4 4 8 4 4 4% 4 5 4 4 4 % 4)1 41 4 4 4 5 4 5 4 5 8 6 4 6 4 6 8 6 *6 4 8 8 8 5 8 6 8 6 4 6 §4 6 8 6 Dex. Wheat. Oz. 1 Same Same Same, Same. Same. Same, Same. Same 2 Milk. Oz. 5% Water. Oz. Malt- EXT. Oz. 1% lljS Pot. Bicarb. Sol. Drachms. (but without wheat). (but with dextrinized wheat). i% 2K (but % oz. more milk to each tube). 15" 3 4 3 4 20 10 2% 3 3 3 zy. iM 2^ 24 24 15K 17)1 'Si 14)1 14^| 26 13 15 22 21 21 21 21 24 3M 3)1 3)1 41 1% 3^ 2 H 2 H 2 H 2% 2 *Each tube of 4 ounces of distilled water and 3 drachms of Nestle's food. fBarley-water. JDistilled water. §1% ounce s of Nestle's, % ounce of malt-extract, and 24 ounces of distilled water. (Case II.) Date. 1902. Dex. Wh. Dist. Barley Malt- 11 56 Pot. No. Oz. Wheat. Milk. Water. Jelly. ext. Bicarb. Oz. Oz. Oz. Oz. Oz. Sol. Drachms. May 28 . . 7 6 1¥ 14 28 3 % 3)1 3)1 May 29 . . 7 6 lg 24^ 17% 2 May 30 . . 7 7)1 7)1 i)! 35 14 3% 3)1 2 May 31 . . June 2 . . 10 7 2V 1)1 52 35 21 14 3 2 June 5 . . 7 7y 2 iy 2 35 14 4 Keller's Malt-soup. Take of wheat-flour 2 ounces and add to it 11 ounces of milk. Soak the flour thoroughly and rub it through a sieve or strainer. 232 INFANT-FEEDING. Put into a second dish 20 ounces of water, to which add 3 ounces of malt-extract; dissolve the above at a temperature of about 120° F. and then add 2 1 / 2 drachms of 11-per-cent. potassium-bicar- bonate solution. Finally, mix all of the above ingredients and boil. This gives a food containing: albuminoids, 2 per cent.; fat, 1.2 per cent.; carbohydrates, 12.1 per cent. There are in this mixture 0.9 per cent, of vegetable proteids. The wheat-flour is necessary, as otherwise the malt-soup would have a diarrhceal tendency. The alkali is added to neutralize the large amount of acid generated in sick children. Biedert emphasizes the importance of giving fat, rather than reducing its quantity, in poorly nourished children, and cites the assimilability of his cream- mixture or of breast-milk in underfed children as proof of his as- sertions. The author has used this malt-soup most successfully in the treatment of athrepsia (marasmus) cases, in which the children were simply starved. On studying the ingredients one can easily see that the malt- extract and the dextrinized wheat are the highly nutritious agents. We know that dextrinized wheat is very well absorbed by some of the youngest infants. The addition of the potassium bicarbonate served to render the food markedly alkaline, which is an extremely important thing. When milk was added with the object of in- creasing the percentage of fat and proteid, we deviated from the quantity as originally recommended by Keller. Colic and gastro- enteric fermentation were invariably encountered. A study of the accompanying weight-chart is extremely interesting. Case II. — The child, S. N., born of healthy parents, was put to the breast on the second day after birth. On the third day after birth there was a profuse flow of milk. The infant appeared quite well satisfied after nursing. The child was nursed every two hours; was changed from the right to the left breast at every other feeding. Fifteen to twenty minutes after each nursing there were symptoms of restlessness and constant crying. The legs were flexed on the abdomen; there were eructations and all the evidences of colic. The child cried at least one hour, until it fell asleep from exhaustion. This state of affairs continued each day for at least two weeks. A speci- men of breast-milk was examined by a chemist and was found to be perfectly normal in its elements and in their relative per- centages. The family was greatly distressed at its continued crying and apparently colicky condition, but was surprised, in spite of this condition, to find that the infant gained between 4 and 6 ounces. It was necessary to give 1- to 2-grain doses of chloral hydrate at MILK IDIOSYNCRASIES IN CHILDREN. 233 ■ToundtS « T: : j ..... ; ?n~ V,im\ i-V— . ;. ,| | 1 44' ~r T^fMW.f |l— \-\- - P ¥./, J - Jg 1 : ! | \ j || ; 1 1 1 1 1 ] 1 1 L , ■ j \ J- *<"** V ; I w/ft \ : ; &." . —" .; : . § < CO a o hi a ^H rt r^t o> P& >■ O CD H -P M 3 -T] o ,Q o -P H cS -d w cS E£ u, 234 INFANT-FEEDING. night to procure sleep. We finally decided to change the mother's milk and to substitute a wet-nurse. The child behaved just as badly with the wet-nurse; had the same crying spells shortly after nursing, which continued frequently for one hour. When the breast was discontinued for one day and barley-water or albumin-water substituted, the child would appear comfortable, and not have the pains which we noted while feeding breast-milk. An interesting point is the fact that all infants having the milk idiosyncrasy had elevated temperatures, ranging from 101° to 102° F. continuously. The stool was filled with large, cheesy, curdy masses. To aid the assimilation of the milk, small doses of pancreatin and bi- carbonate of soda were given; with the idea of slightly peptoniz- ing the milk, essence of caroid, a / 2 teaspoonful before each feeding, was also prescribed. In addition thereto small quantities of es- sence of pepsin and hydrochloric acid were given after each feeding, to aid the digestion of this food. Neither of these medications relieved the condition, and I finally decided that breast-milk was not adapted for this child. We next resorted to very diluted cows' milk, using 1 part of milk with 3 parts of oatmeal-water. We gradually increased the strength until y 2 milk and % oatmeal- water was given. Milk, however, in any form, whether diluted or pure, was poorly borne. When cereal decoctions were substituted, they were invariably better tolerated. The same was true when soups and broths were given. The latter were always well borne, and the moment milk was added, no matter in what form, trouble was immediately encountered. Case III. — Another baby, an equally instructive case, was brought to my office by Dr. Hecht, of West Hoboken, N. J. It could not assimilate milk in any form. This child not only had dyspeptic and colicky symptoms, with flatulence and cheesy stools, but also evidences of fermentation in the bowel, and invariably had acute febrile attacks with temperature ranging from 101° to 103° F. whenever milk was fed. This gastric disturbance was only apparent after milk-feeding. The child behaved well when sub- stitute feeding other than milk was given. Almond-milk was one of a series of foods given which was not only well borne, but was well adapted for nourishing when milk was not tolerated. It was found wise, if 4 ounces of milk had been previously given, to substitute at the next feeding 4 ounces of barley-water or oatmeal-water, and to feed 4 ounces at regular intervals of three or four hours each. Almond-milk can be given in the same quantity and at the same intervals as breast-milk. It must be sweetened by adding 1 teaspoonful of sugar to each 4 ounces of food. Delicate infants MILK IDIOSYNCRASIES IN CHILDREN. 235 require 2 ounces — repeated every two or three hours. If this quantity is well borne by the stomach, then 1 ounce more can be added every two days. Almond-milk contains vegetable proteids and is exceedingly valuable as a milk-diluent. It serves well in- stead of barley-, rice-, or oatmeal- water if it is sweetened with cane-sugar. CHAPTER XXXIV. Laboratory Modification of Milk. It is now several years since a Walker-Gordon milk- laboratory was established in New York. Their method of feeding infants is based on mixing the ingredients in such combination that, when combined, they should re- semble certain chemical formulae of breast-milk at various ages. Blanks are given the physician, which are filled out according to the individual requirement. The age and weight are noted. Fat, sugar, proteid, and water are pre- scribed in percentages. We are therefore able to state that the food ordered contains a definite percentage of fat, sugar, caseinogen, and lactalbumin. The same is also true regarding the heating of food. We can prescribe the food sterilized, pasteurized, or raw. A great many changes can be made. We can increase or decrease the fat; the same is true of sugar and proteids. My advice to those using modified milk is to begin with low proteids. An infant at birth, if deprived of breast-milk, should never receive more than 0.50 per cent, of proteids, in the beginning of laboratory feeding. Some infants do very well on 0.25 per cent, of proteids soon after birth. It is a simple matter to note the infant's condition, its stools, its sleep, and its weight. If the above-named conditions are satisfactory, then we can increase the proteids, the fat, and the sugar. Note conditions every day, and have the mother or nurse in charge of the infant report the slightest disturbance. Vomiting, if present, its frequency and character, should be carefully noted. So also should colicky symptoms, eructations, flatulence, and greenish, curded stools. Constant crying, disturbed sleep, and restlessness are all factors that need correction and supervision. (236) LABORATORY MILK. 237 The quantity of food prescribed, depends upon the requirements of each child. Some children can take 3 ounces at one feeding while others appear satisfied after taking 2 ounces of food. Examples. — For a child at birth. Fat 2.00 ^ Sugar 5.00 Proteids 0.50 Lime-water 5.00 Formula I. Or:— Fat 2.00 Sugar 5.00 Proteids 0.75 Lime-water 5.00 Formula la. Milk, raw, pasteurized, or sterilized. Quantity of food to be given, 2 ounces every two hours. My preference for food prescribed at a laboratory where germ-free milk is obtainable is to prescribe it raw. When constipation is encountered the raw milk will mod- ify such conditions. If diarrhoea or looseness exist, then my preference is to use heated milk : sterilized about ten to twenty minutes. If the infant thrives, the ingredients can be increased; also the quantity at each feeding: — Fat 2.50 ^ ^ Q ™ I Formula II. Proteids 1.00 [ Lime-water 5.00 J Still later, if conditions warrant it: — Fat 3.00 "} Sugar 6.00 ( ^ , TTr _ , . , > Formula III. Proteids 1.50 ( Lime-water 5.00 J 238 INFANT-FEEDING. In this manner we can gradually increase the per- centage of ingredients until whole milk is ordered. When abnormal conditions prevail, — such as loose bowels, — then barley-water can be substituted for the sterile water. The following formula was recently prescribed at the laboratory for a child, 1 year old, with very loose bow- els : — Whole milk 15 ounces Rice-water 14 ounces Dextrinized wheat 1 ounce Dry cane-sugar 1% ounces Cornstarch 2 teaspoonfuls . Formula IV. To be thoroughly mixed, sterilized 20 minutes, and divided into five feedings, each bottle containing 6 ounces. When the bowels acted better, and had a more solid consistency, I added malt-extract, 1 / 2 teaspoonful to each bottle. When improvement was noted the above formula was changed to:- — Whole milk 28 ounces Barley-water 20 ounces Cornstarch 1 ounce - Formula V. Dry sugar 6 drachms Dextrinized wheat 2y 3 ounces Sterilize, divide into eight bottles of 6 ounces each. The following case illustrates successful modified-milk feeding with milk prepared at Walker-Gordon labora- tory : — Baby A, 4 months old, was seen by me September 19, 1901, with the following history: It was the first baby, forceps delivery, podalic presentation; weight at birth, about 6 pounds. Family his- tory excellent. Nursed at mother's breast about four weeks, but, owing to a scanty flow of milk, she required additional hand-feeding. The baby received milk and barley-water, sterilized or boiled. A bottle was given after each nursing (so-called mixed feeding). Result: Constipation; relief given by soap-suds enema. This condition lasted about six weeks. The child had colic of a very severe form and also tenesmus: i.e., constant straining. LABORATORY MILK. 239 Child was weaned of the mother's breast; food ordered was: — Milk 8 ounces. Barley-water 16 ounces. Milk-sugar 3 teaspoonfuls. Lime-water 2 teaspoonfuls. Salt 10 grains (pinch) . Sterilize thirty minutes, divide into eight feedings, and feed every two hours. When about 2 months old, child had greenish, spinach-like, very slimy stools, also containing white curds. The infant appeared hungry or thirsty all the time, was restless, had insomnia, and suf- fered with colic. There was no vomiting. A physician ordered the milk discontinued and barley-water given instead. The child became extremely emaciated; hence was removed to the sea-shore. At the sea-shore Dr. J. ordered: — ■ Milk 1 ounce. Boiled water 3 ounces. Milk-sugar and salt. This food was quite well tolerated. When oatmeal-water was given instead of barley-water, to offset the constipating effect, a miliary eruption appeared. During the second week of September the child still had diar- rhoea. Stools still greenish, containing mucus and shreds. The rectum prolapsed from constant tenesmus. Cereal milk was tried, but with no success. The above is the clinical history given to me by the mother of the infant. Present condition: A very frail-looking infant, rather emaci- ated. Poor circulation, cold extremities, pallor of skin, anus slightly excoriated, and nsevus on right side of thorax. Temperature normal in rectum, 98 4 / s ° F.; pulse, 120; respira- tion, 28. Throat normal, tongue moist and has grayish-white, fur- like coating. Heart-sounds feeble; slight bronchitis, diffuse sonor- ous and sibilant rales heard on both sides of the chest. Stomach very markedly distended. Abdomen tympanitic on percussion. Colon distended. Liver enlarged. Spleen not palpable. Diagnosis: Chronic dyspepsia, atrophy due to mal-assimilation of food, and rickets. Prognosis: Fair. 240 INFANT-FEEDING. Weight. September 19 8 lb. 15 oz. (including shirt and belly-band). 25 9 lb. 12 " Gained October Gained October Gained October Gained October Gained October Gained .... November 30 . With clothes ;. 13 " 2 10 lb. 2 " 6 " 9 10 lb. 9 " 7 " 16 11 lb. 2 " 9 " 23 11 lb. 14 " 12 " 30 12 lb. 6 " 15 lb. 7 " A study of the weight-chart will prove very interesting. The dyspeptic and rachitic baby with cold extremities is to-day a beautiful child, well developed, and was not seen by the author for several months — until it was necessary to vaccinate. Ordered: Syr. rhei arom., 3j every four hours, to cleanse gastro- intestinal tract. Also: — B Strychnine sulphate 0.002 Saccharin 0.06 Decoction of cinchona (llava) 60.0 M. Teaspoonful after feeding three times per day. The above as a cardiac and vascular stimulant. Sept. 20th: Food ordered at Walker-Gordon laboratory: — Fat 2.50 Sugar 6.00 Proteids 1-50 Lime-water Vis Seven feedings of 6 ounces each. Use raw milk. Feed every two and one-half hours. The following day the child slept from 8 p.m. till 4 a.m. — eight hours continuously. Had three pasty stools. Infant appeared satis- fied after bottle. It was then ordered (September 22d) :— LABORATORY MILK. 2-il Fat 3.0 Sugar 6.0 Proteids 2.0 No alkalinity. Raw milk. Seven feedings, 6 ounces in each. Feed every two and three-fourths hours. Child seemed much better satisfied after feeding; vomited once; had two stools, both of yellowish color, and of good consistency. One stool at 5 a.m. and one at 5 p.m. September 28th: — Fat 3.50 Sugar 6.00 Proteids 2.00 Pasteurize the food. Six feedings of 6 ounces each. Feed every three hours. When bowels acted too frequently I pasteurized the food; not otherwise. October 6th ordered: Bran and sea-salt baths every second night; temperature of bath 95° F. ; followed by brisk rubbing to stimulate the circulation. The digestion of the infant being excel- lent, stools regular, the percentage of ingredients was increased: — Fat 4.00 Sugar 6.00 Proteids 2.50 Use barley -jelly instead of water; alkalinity, 5 per cent. Heat to 167° F. Six feedings of 6 ounces each. Feed every three and one-half hours. Child is excellent, gaining in weight; sleeps well; stools normal; has no colic. Discontinued laboratory feeding. Home modification: — Pure raw cows' milk 30 ounces. Barley-water 18 " Peptogenic powder 3 teaspoonfuls. Divide into six bottles; warm each bottle before feeding. Feed every three and one-half hours. Add the barley-water to the raw milk and divide into six equal bottles, then place in refrigerator until feeding-time. At feeding- time empty a bottle into a clean saucepan, add the peptogenic, and 242 INFANT-FEEDING. warm to the temperature of 100° F. for ten minutes; then boil quickly for one minute and cool to feeding temperature. For the relief of constipation: — Infus. senna comp 2 ounces. Saccharin 1 grain. M. Teaspoonful every three hours until bowels move. Gradually abstracted one ounce of barley-water and added one ounce of pure milk, until after a few weeks the child received whole milk, sweetened with one teaspoonful of granulated sugar; 8 ounces every four hours. Also ordered six ounces of chicken-soup; steak-juice, gradually thickened with cereals; some egg-crackers, zwieback, and bread- crumbs in soup. Later: — Milk (raw) 8 ounces. Cream 1 / 2 ounce. Granulated sugar 1 teaspoonful. Warm in a saucepan and feed every four hours. Illustrative Case — Unsuccessful Laboratory Feeding. — N. R, a healthy female, was put, soon after birth, on modified milk. October 14th: Fat, 2.0; milk-sugar, 5.0; albuminoids, 0.75; lime-water, 1 / 16 . Eight feedings; 2 ounces in each. October 17th: Constipation. Fat, 2.5; milk-sugar, 6.0; albu- min, 1.0; lime-water, y i6 . Nine feedings; 2 1 / 2 ounces in each. October 27th: Fat, 3.0; milk-sugar, 6.0; albuminoids, 1.0; lime- water, Vis; barley -jelly, 1 / 1B . Ten feedings; 3 ounces in each. November 5th: Fat, 3.5; milk-sugar, 6.0; albuminoids, 1.0; lime-water, Vis; barley-jelly, Vis- Ten feedings; 3 ounces in each. November 17th: Fat, 4.0; milk-sugar, 6.0; albuminoids, 1.5; lime-water, 1 / 20 ; no barley. Ten feedings; 3 ounces in each. November 19th: Curded stools, dyspeptic diarrhoea. Fat, 4.0; milk-sugar, 6.5; albuminoids, 1.0; lime-water, Vac Ten feedings; 3 ounces in each. The child did not increase in weight, had a rectal temperature of 100°, slightly furred tongue, vomited curds, had greenish stools containing undigested particles of fat and true casein and large masses of mucus. The diagnosis of dyspepsia infantum was made; hand-feeding was stopped, the child's alimentary tract was cleaned by giving cascara sagrada, and a proper wet-nurse was secured. The infant at this time was about 6 weeks old. The child nursed very well, and after a few days the stools were normal, both in LABORATORY MILK. 243 consistency and color. The infant gained steadily from 4 to 6 and sometimes 8 ounces per week, until she was 7 months old, when suddenly the weight remained stationary. The child was bright and cheerful, but I deemed it necessary to have the milk of the wet- nurse examined by a competent chemist; a specimen of the same was secured in the usual manner described by me in a previous sec- tion on "Specimen of Breast-milk for Chemical Examination." This specimen was examined for the author by John S. Adriance, the chemist of the Nursery and Child's Hospital, who reported the following: — Fat 2.000 per cent. Sugar 7.431 per cent. Proteids 0.882 per cent. Ash 0.162 per cent. Total soAds 10.475 per cent. Water S9.525 per cent. Specific gravity at 70° F 1.0316 Reaction alkaline. In the chemical result above given it is very evident that a deficiency in the proteids exists; hence it accounted, not only for the stationary weight, but for the late dentition. The child did not gain an ounce in one month. We discharged the wet-nurse. The following food was ordered: — Milk 3 ounces. Cream 2 teaspoonfuls. Oatmeal-jelly 3 ounces. Lime-water 1 drachm. Milk-sugar 1 teaspoonful. Salt 1 pinch. Sterilize the above and feed every three hours, the above quan- tity being for one feeding. After the infant had taken this food for 6 days it was cheer- ful, had had one and two yellow stools daily, and gained 6 ounces in 6 days. The above case will illustrate: — 1. That the child was decidedly dyspeptic while taking its modified milk for about 6 weeks. 2. That for about 6 months the infant thrived very well on the milk of a wet-nurse. 3. That the stationary weight of the infant and the chemical examination of the milk of the wet-nurse showed deficient pro- 244 INFANT-FEEDING. teids, which accounted for this non-increase in weight and the late- ness in dentition. 4. That a proper milk-mixture, which agreed very well, suited the requirement of this infant, and emphasizes the fact that we must individualize in each and every case. According to Starr, the question naturally arises: "Why should a food capable of being prescribed to ap- proach so nearly breast-milk in chemical composition, so uniform in its make-up, so sterile, and so easily and ac- curately varied to meet digestive emergencies, fail when put to a clinical test?" The answer is that it is impossible to make an emul- sion like milk from its component parts by a synthetic process. Let it therefore be distinctly understood that, once a milk-emulsion is broken up, as is done in centri- fuging milk and removing the cream, mixing the whole will never restore the uniformity of the emulsion that existed prior to this division. Time and again have I examined a drop of milk under the microscope and found an unevenly-divided emulsion of modified milk, resembling colostrum-milk. The macro- scopical examination of modified milk will always show a large amount of butter-fat swimming on top of each bottle of milk when it is cool. If this fat is part of the formula prescribed, then the modified milk does not con- tain its original amount of fat, and much more must be prescribed, to allow for the separation of the same. Hence it would seem that the percentage portion of the food must necessarily be incorrect. Starr says, also, that "in its composition all the fat is removed by a separator, and the food as prepared for the infant is a recombination of this fat and an alkaline so- lution of the proteids and sugar. In a word, the natural emulsion is destroyed. This, I think, in some way lessens the digestibility of the proteids and leads to conditions either of malnutrition or to an irritative diarrhoea with the expulsion of the undigested proteids in the form of LABORATORY MILK. 245 compact curds — and this, too, despite changes in the pro- portion of the proteids; for the partially starved children are attacked with vomiting or diarrhoea with fever if the percentage of proteids be increased (say, to 2 per cent, at ten months), and those having irritative diarrhoea are not benefited until the percentage is cut down to a starva- tion-point (0.75 per cent, in a child of three months still showed numerous curds in the evacuations). What a con- trast to normal breast-milk, an emulsion having over 2 per cent, of proteids (Leeds) ! "I have never seen an infant from two to ten months able to stand a laboratory-mixture of stronger proteid percentage than 1.50, and have often seen cases of two months and more unable to digest a percentage of 0.50." This last statement of Starr's I cannot indorse. Sev- eral children fed by me were able to digest 2 and 3 per cent, of proteids at 6 to 10 months of age. The case of successful modified-milk feeding here given illustrates how a child about 5 months old received and assimilated 2 per cent, of proteids, and when less than 6 months old digested 2.50 per cent, of proteids. Thus it is apparent that weak, dyspeptic infants require individualization. In domestic modification, of course, the same care must be taken to secure clean, pure milk and cream from healthy, well-kept cows. This is quite possible now in ISFew York, and is becoming easier each year, as more attention is being given to infant-feeding and greater demand is being made for a pure milk-supply. Pasteur- ization is as readily done in the nursery as in the labora- tory. Accurate measurement of quantities and cleanliness of vessels and feeding-bottles is equally possible and, in my experience, quite as certain at home as in the -shop. "The milk and cream from a dairy may vary slightly in chemical composition from day to day, but this varia- tion seems to me to be a minor detail, and of questionable importance when compared with the separator's destruc- tion of the physical properties of the basal milk. One 246 INFANT-FEEDING. certainly would not sacrifice everything to chemical ac- curacy." Clinical experience has demonstrated the fact that some children will thrive on condensed milk in spite of faulty hygiene, while others will not thrive in the best environment with the best form of feeding; again, some children will thrive on modified milk, others will not. Some cases seen by the author suffered with intense con- stipation, having clay-colored stools. In one instance, in which two children in one family were constantly fed on modified milk of varying proportions, the formulae were changed at least a half-dozen times with the usual increase of fat and sugar and lowering of the proteids, and in spite of this fact, after repeated trials, and no benefit, this feed- ing-method was abandoned. A child recently seen by the author did not gain one ounce in four months. This was one of the reasons that prompted the family to change both the physician and the food. The child, about two years old, was very pale, restless at night, quite peevish during the day, and decidedly backward in development. It could neither speak nor walk, although the teeth were well developed. From the time the modified milk was discontinued, and a nitrogenous diet given, the infant im- proved, and from last reports is quite well developed. Do not let us blindfold ourselves with the belief that an infant is thriving unless our baby shows a regularity in the increase of weight, sleeps well at night, for at least from six to nine hours continuously, and, above all, as- similates its food, as evidenced by regular, unaided move- ments of the bowels; such movements should be once or twice in twenty-four hours, have a yellowish-white color, and a mustard-like consistency. If the stool is hard or lumpy or pasty, like putty, then it is certainly abnormal, and shows improper food. The same is also true if the stool contains white particles of cheesy curds, showing a casein indigestion. In one infant, which had taken modi- fied milk continuously for seven months, an obstinate con- LABORATORY MILK. 247 stipation was only relieved after full doses of codliver-oil and extract of malt were given for several weeks — aided by massage, besides changing the diet. It is therefore very necessary continually to watch the baby, and when abnormal conditions — such as anaemia — prevail it is wise to give restoratives for a long period in addition to the food. Try to note if the food is deficient in its nutritive elements, and, if so, change the formula so as to adapt it to the baby. Do not give medicine when the quality or quantity of food is deficient. Remedy the food first; then, if not satisfied, give medication. PALLOR OF THE SKIN. An unusual pallor of the skin, and also of the con- junctival mucous membrane, has frequently been noticed in modified-milk babies. In one instance an extreme leucocytosis was noticed for the treatment of which iron was given. An examination of a drop of blood showed a diminution of the red blood-corpuscles and an excess of the white blood-corpuscles. A decided hsemic murmur was noticeable in the vessels of the neck, in a child, two years old, which had been fed continually on modified milk. Craniotabes, softening of the cranial bones, as well as very late closing of the anterior fontanelle has also been observed in some children fed with this form of food. A boy, 4 years old, a typical Walker-Gordon baby, who was fed exclusively on modified milk, now shows typical knock-knees, besides having been under the treat- ment of his physician for a general furunculosis of. the scalp. The furuncles were of such size that they required incision several times; others opened spontaneously. Thus, I fully agree with Louis Starr, of Philadelphia, who, in his paper, 69 says: "I must not be understood as condemning laboratory-milk absolutely ; if its introduction has done nothing else, it has greatly advanced substitute 69 Archives of Pediatrics, page 7, January, 1900. 248 INFANT-FEEDING. infant-feeding, by fixing the attention of the profession upon the importance of cleanliness and accuracy in the quantity and chemical composition of cows' milk foods and by placing the whole question upon a higher scientific plane than it has ever reached before." Sometimes predigested food is ordered with the addi- tion of peptogenic powder, the predigestion to be done at the laboratory. A great many physicians who formerly condemned percentage feeding have become converted to this method. Constipation, which is frequently encountered, can be remedied if the chemical and clinical causes are consid- ered. Superheated milk is one of the main causes. In spite of the many failures reported by feeding sterilized milk, we see hundreds of babies brought up on this line of feeding. Chemical changes are produced by subjecting the milk to a temperature of 212° F. for thirty minutes and fre- quently forty-five minutes. These changes take place, in the most vital elements of milk, such as albuminate of iron, phosphorus, and possibly in the fluorin. These ele- ments are present in a vitalized form, as they are derived from tissues that contain them. When we consider that children require phosphatic and ferric proteids in a living form, then we cannot continue with boiled- or sterilized- milk feeding for a too prolonged period without causing structural . weakness. There are times when raw milk will cause too fre- quent stools; then it may be advantageous to resort to pasteurization or to heating the milk to 167° F. for about twenty minutes. I am convinced that prolonged, sterilized-milk feeding will result in rickets. I have had many cases of weak spine and bony structure in which nothing but improper food could be regarded as the etiological factor. These children were among the well-to-do, among whom excel- lent hygiene and proper nursing habits were rigidly en- LABORATORY MILK. 249 forced. Improvement was noted when sterilized milk was abandoned and raw-milk food, in addition to raw muscle- juice, grape-juice, and orange-juice, was prescribed. A great many unsatisfactory reports are heard regard- ing laboratory feeding. Some condemn laboratory feed- ing because it is patented. Others condemn the method after noting poor results. The strongest opponents of this method are Jacobi, of New York, and Starr, of Philadel- phia. It may be safe to add that they may yet be con- vinced of the value of procuring sterile food handled by competent people whose scrupulously clean methods must appeal to even the most prejudiced. A child seen by me recently, in consultation with Dr. John Logan and Dr. Julius Martinson, of this city, may prove very interesting. The child was a bottle-fed infant — less than a year old — suffering with vomiting and diar- rhoea; the symptoms of cholera infantum were very pro- nounced. The diagnosis of acute milk poisoning was made, and concurred in by the attending physicians. The milk was procured from a small laboratory in our city. I have had good reason to complain of peculiar methods of handling milk. Sour milk has been sent to patients of mine by unscrupulous dairymen after they had secured evidences of my good-will. Surely the Walker-Gordon laboratory cannot be held responsible for the mistakes or carelessness in other dairies or creameries. More recently the author has tried raw milk and cream modified at the laboratory, and has noted a great difference in the assimilation of such modified milk. Thus, while some experience herein reported has been bad, it is possible that a good part of the fault is due to overheating the milk. Changing the character Of the pro- teid and altering the chemical relationship of the various ingredients must change its assimilability, and hence the author would urge those who use the laboratory to insist upon having formulae compounded by using raw milk and fresh cream. CHAPTER XXXV. Fokced Feeding. This is commonly known as gavage. This consists in forcing a small feeding-tube, a No. Y rubber catheter, through the mouth and pushing it forcibly toward the pharynx and directly into the stomach. This feeding- tube consists of a black hard-rubber or glass funnel to which is attached a piece of rubber tubing about ten inches long; then a small glass tube (a connecting tube) over which is drawn the rubber No. Y catheter. In case of emergency, nothing is handier as a connector than the glass portion of the ordinary medicine-dropper, the smaller end will serve to connect with the rubber catheter mentioned above, and over the larger portion of the medi- cine-dropper we draw the rubber tubing connected with the funnel. This little apparatus has been very neatly combined for the author's use by Messrs. George Tiemann & Co. (See Fig. 40.) Having pushed this small catheter into the stomach, we pour the food, usually several ounces of peptonized milk, or dextrinized barley and milk, or albumin-water, or the white of a raw egg mixed with half of a teacup of coffee and milk; or, if desired, a good concentrated soup, or bouillon, or broth, can be used. The same interval governing ordinary meals should be more strictly adhered to while this process of feeding is used. It is well under- stood that all instruments, utensils, and food must be strictly clean and sterile. Place the child flat on its back, and, first, pin either a heavy blanket or a stout sheet securely behind the body so that the hands are pinned down; have the assistant hold the child's elbows securely on each side; then force (250) FORCED FEEDING. 251 the mouth open and quickly pass the catheter, pour the food into the funnel, and when the funnel is empty with- draw the catheter as quickly as possible. If this forced feeding is done very slowly or clumsily, then nausea and sometimes vomiting will be produced thereby. Hence, the technique should be carried out as carefully as pos- sible. Fig. 40. — Author's Apparatus for Irrigating Rectum and well Adapted for Stomach-washing (Lavage) and also for Forced Feeding (So-Called Gavage). Also Useful in Nasal Feeding. Great care should be used in gavage. When children have teeth, the nurse must separate the jaws. For this purpose a piece of cork or a spoon covered with linen will answer as a mouth-gag. Accidents may happen if this precaution is not taken. The writer has seen several chil- dren who had bitten the catheters and swallowed them. In one of these cases the tube was easily dislodged by an emetic. Another required a gastrostomy. 252 INFANT-FEEDING. NASAL FEEDING. ]STasal feeding has long been in use where diseases of the mouth or spasm of the jaw or intubation in diphtheria rendered swallowing difficult. A thin rubber catheter is attached to a long rubber tube ending in a funnel; this is the same apparatus that has been described on page 250. Modus Operandi. — Lay the child flat on its back and have a large sheet pinned over the body, so that the hands are firmly held; have the feeding-mixture all prepared, so that no time will be lost. A soft-rubber catheter, lubri- cated with vaselin or glycerin, is gently pushed into the nostril and glided through the pharynx into the oesopha- gus and stomach. When the tube is in the stomach, pour the required • amount of food into the funnel so that it flows in the stomach. When the proper amount has been used, withdraw the catheter from the nose, and boil it. in warm water to properly sterilize it for the next feeding. Quantity of Food. — The quantity of food used in nasal feeding should be somewhat less than is ordinarily used in health. It is understood that only liquid foods — like peptonized milk, sterilized milk, soups, and broths, or bouillon — can be used for feeding in this manner. A thin emulsion of egg can also be used. Owing to the fre- quency of both nausea and vomiting, which may be in- duced by irritation of the fauces, while the tube is gliding through the pharynx into the oesophagus, a much larger interval must be given between the feedings. It is de- sirable to introduce the tube rapidly and remove it rapidly if it is at all possible. Accidents will result in nasal feeding if a large quantity of liquid food is regurgitated through the oesophagus into the mouth and aspirated through the larynx into the trachea. In some instances it is easier to pass a soft, flexible catheter through the right or left nostril into the oesopha- gus, and forcibly push the same into the stomach. This is a very simple process, and I have never yet been able FORCED FEEDING. 253 to pass the tube into the larynx while gliding it toward the oesophagus. All food should be given warm — prefer- ably between 98° and 100° F. Small quantities of milk, strained gruel, broth, or albumin-water will be far better digested than heavier food. In some instances, where milk is not well borne, the ordinary unsweetened cream, in the proportion of 1 teaspoonful of cream to 3 ounces of water, will serve quite well. In other cases I have used very successfully several teaspoonfuls of Mellin's food diluted with an ounce of raw milk, to which 1 ounce of boiling water was added. This latter mixture is highly nutritious, and scalds the milk, and does not require either pasteurization or sterilization. Eskay's food has served me very well in one case of gavage. Meat-juice and expressed steak-juice or roast-beef juice should not be forgotten. CHAPTER XXXVI. Feeding in Diphtheria-Intubation Cases. When an infant has a foreign body — the intubation- tube — in its throat, swallowing is more difficult, because the epiglottis cannot close entirely. Frequently, while swallowing there is coughing, gagging, and regurgitation, caused by fluids (food) trickling into the trachea. In this manner, it is claimed, schluck-pneumonia has fre- quently been caused, though Northrop and many others deny the possibility of this condition. If the child's head is turned to one side — either side — and swallowing is pro- voked in this manner, we can sometimes avoid this trick- ling into the trachea. Another method is to lay the child flat on its back and allow the head to hang lower than its body, and to feed slowly with a spoon. This is known as the Casselberry method of diphtheria feeding. If this method is not satisfactory, and if we find that "we cannot get enough food into our patient, then we can resort to rectal feeding. Clinical Illustration of Rectal Feeding in Diphtheria. — The fol- lowing clinical record will illustrate the manner employed in rectal feeding in private practice, with the aid of a competent trained nurse, in a case of severe laryngeal diphtheria which required in- tubation; child seen in consultation with Dr. H. Weinstein:- — Feeding by mouth was discontinued while the child had a tube in its larynx: in all, a period of five days. The feeding was accomplished by first flushing the rectum and colon with a soap-suds enema to clean the bowel. After the bowel was emptied the peptonized food was introduced high into the colon. Food used: — Peptonized milk 1 ounce. Starch-water 1 ounce. To make starch-water take 1 teaspoonful of starch to 1 ounce of water. (254) FEEDING IN DIPHTHERIA-INTUBATION CASES. 255 Alternate with: — Peptonized yolk of egg. Starch-water, 1 ounce. Feed per rectum every four hours. One day's record of case: — 9.00 a.m. Intubated. 10.30 " Rectal irrigation (soap-suds). 11.00 " Nutritive enema (which was retained) : — Peptonized yolk of egg. Starch-water, 1 ounce. 2.00 p.m. Bowel irrigated. 3.00 " Nutrient enema (which was retained) : — Peptonized milk 1 ounce. Starch-water 1 ounce. 6.00 " Greenish stool with undigested milk-curds. Bowel irrigated. 7.00 " Nutrient enema (which was not retained) : — Peptonized yolk of egg. Starch-water, 1 ounce. 10.00 " Bowel irrigated. 10.30 " Nutrient enema (which was retained) : — Peptonized milk 1 ounce. Starch-water 1 ounce. Bear in mind that the rectum absorbs, and does not digest. Hence, all food must be peptonized. The method is very simple. First: Always cleanse the rectum. This is done by washing the rectum with an enema of a pint of soap-water made by dissolving ordinary Castile soap or glycerin soap in warm water. The temperature of the soap-water should be 100° to 110° F. Quantity, from 1 to 2 pints. After the rectum is cleaned, and the faecal movements all passed, it is advisable to wait about five minutes to give the rectum a chance to rest. Then we proceed to inject the rectum with a suitable quantity of peptonized egg. Small quantities are better borne than large quantities; hence, no more than 1 to 2 ounces should be thrown in at one time. 256 INFANT-FEEDING. For rectal feeding the following are required: — 1. Fairchild peptonizing tubes. 2. Starch-water made by adding 1 teaspoonful of starch (raw) to 1 ounce of water (lukewarm). 3. Fresh-laid eggs. 4. Fresh raw milk. 5. Rectal syringe or a fountain-syringe. 6. Colon-tube for flushing the colon and rectum; the same tube can be used for injecting the peptonized food after the enema has acted. The following formula will give an idea of the way in which food is to be prepared for rectal injection: — Take 2 teaspoonfuls of ordinary starch and rub the same up with an ounce of lukewarm water. This makes a very milky mixture. To this mixture we add the yolk of 1 egg, and one-half of an ordinary Fairchild pepto- nizing tube. This is to be slowly, but forcibly, injected into the rectum. Various methods of injecting can be used, the simplest being with the aid of a bulb rectal syringe, known as the infant's rectal syringe. (See Fig. 42.) Another method consists in pouring this emulsion of starch-water and peptonized egg into a funnel ending in a rectal tube, a so-called rectal feecling-tube made by Tie- mann, of ]STew York City. (See Fig. 40.) The secret of success is undoubtedly the amount of food brought into a child's body during its illness, and, the more food absorbed the greater resistance will the child have. It is advisable not to overtax the rectum; hence, my method of feeding is to use the peptonized yolk of egg with starch-water as mentioned above, and follow it — four hours later — by substituting an ounce of peptonized milk instead of the yolk of egg. With this ounce of milk an ounce of starch-water should be combined. If there is looseness of the bowels, FEEDING IN" DIPHTHERIA-INTUBATION CASES. 257 and the food will not remain in the rectum, then 1 or 2 drops of the ordinary tincture of opium added to each enema will soon quiet the irritation of the rectum, and thus aid in retaining the nutrient enema. At the Willard Parker Hospital feeding in diphtheria is chiefly done by gavage through the nose. The child is placed on its back and fed in the same manner as de- scribed by me under the heading "Mouth Gavage." While making rounds through the wards I have seen children gavaged through the nose, some lying on their backs and others while sitting erect. The only objection to this form of feeding is the possibility of pushing membrane downward through the nose or naso-pkarynx. This might result in an infection of a healthy surface or in denuding membrane; epistaxis is likely to occur. CHAPTER XXXVII. General Rules for Rectal Feeding. In another chapter entitled "Rectal Feeding in Diph- theria" attention has already been given to the method Fig. 41. — Author's Double-Current Rectal Tube for Flushing the Colon and Rectum and Used for Rectal Feeding. Fig. 42. — Rectal Syringe. of cleansing the rectum, and also to the injection of foods. The same rules are applicable when there is excessive (258) GENERAL RULES FOR RECTAL FEEDING. 259 irritability of the stomach, with constant vomiting and where it is desirable to give the stomach absolute rest. Fig. 43. — Rectal Syringe. Small quantities properly injected will be retained and absorbed much easier than large quantities of food, which will merely serve as irritants and be expelled. CHAPTER XXXVIII. Feeding Children Afflicted with Cleft Palate. An infant born with cleft palate has a greater struggle for existence than a child born healthy, without this de- formity. It is advisable to give the best possible food, and, therefore, breast-milk only should be used. The milk should be drawn from a woman's breast as previously de- scribed in the section on "Specimen of Breast-milk for Chemical Examination." An artificial nipple should be attached to the feeding- bottle, and to the former should be attached a flap of India rubber so made that it fits the roof of the mouth. The pressure of the nipple against the piece of rubber, when in position, converts it into an artificial palate-piece, and prevents the escape of the milk into the nose during the effort of swallowing. This shield is chosen to avoid permitting curdled milk to pass into the recesses of the turbinated bones and to cause aphthous patches. It is advisable to operate on an infant for this de- formity between the third and sixth months of its life, if sufficient progress in its development will warrant it. (260) CHAPTER XXXIX. Infant-stools. Stool of a Nursling. — The stool of a nursling or a baby on an exclusive milk diet should be yellowish in color, smeary or pasty-like in consistency, and have an acid reaction. The smell should be faintly acid, but not disagreeable. The color is due to bilirubin, and the reac- tion depends on the presence of lactic acid, the source of which is the milk-sugar. The only gases present are H and C0 2 . According to Escherich, H 2 S and CH 4 , to which the odor of adult stools is due, are not present. There are no peculiar albuminoids. Those existing in mothers' milk seem to be entirely absorbed. Peptone ex- ists in trifling amount. Srigar is not present. Pancreatic ferment is absent, and sometimes traces of pepsin have been found. Mucus is always present in considerable quantity; also columnar intestinal epithelium. In the stools of nurslings large quantities of lactate of lime can be found; so also we frequently find oxalate of lime, depending on the quantity of oxalate of lime in- gested. UfTelmann has noted the presence of bilirubin crystals in the stools of nurslings, in perfectly healthy children. Miller, who carefully studied the various micro- organisms in the mouth, found that most of them could again be found in the intestinal canal. He further found that certain germs possessed diastasic properties and were capable of producing lactic-acid fermentation. In the milk-feces of nurslings Escherich found two germs; the one he called bacterium lactis aerogenes (or bacterium aceticum, Baginsky) and the other the bacterium coli commune. In the meconium he found proteus vulgaris, (261) 2G2 INFANT-FEEDING. streptococcus coli gracilis, and bacillus subtilis. The number of stools during the first two weeks is from 3 to 6 daily. After the first month the average is 2 stools daily; many infants have 1, others 3 stools daily. This latter is due largely to the excessive quantities of water given to infants. As soon as the exclusive milk diet is changed to the mixed diet we then lose the characteristic infantile stool, and it resembles more that of an adult, though remain- ing softer and thinner throughout infancy. The stools become darker in color, assume the adult odor, and have Fig. 44. — Schering's Formalin Disinfecting-lamp. Well Adapted as a Deodorizer in the Nursery. more varieties of bacteria than those previously mentioned as found in the stool of a milk diet. Reaction of Stools. — Reaction of stools in diarrhoeal disease and in health is chiefly acid or, next in frequency, neutral. Alkaline stools are rare. Green-grass stools, usually acid, are seen in the early stage of dyspeptic diar- rhoea, the color from a pale greenish yellow to grass-green, owing to improper food. Wegscheider has shown that the green color is the result of preformed biliverdin. The condition in the in- testine, upon which the transformation of bilirubin into biliverdin depends, has been generally regarded as one of acid fermentation. INFANT-STOOLS. 263 Experiments. — Pfeiffer's experiments 70 show this for- mer opinion to be wrong. He found that none of the acids formed in such fermentation — lactic, acetic, butyric, propionic, etc. — added to yellow stools outside the body, turned them green, but that they made them deeper yel- low. But dilute alkaline solutions added to fresh yellow stools turned them green after an exposure of thirty to sixty minutes, and strong solutions turned them, first, brown; later, after exposure to air, intense green. Typical Green Stools. — Typical green stools can be produced by giving an infant 2 or 3 grains of bicarbonate of soda. This I have tried dozens of times; the soda must be given for a few days. This explains Pfeiffer's alkaline theory. Typical green stools can also be produced by giving small or even large doses of calomel. If, after having given bicarbonate of soda and produced green stools, we give diluted hydrochloric acid in 5- to 10- drop doses, the yellow color will reappear in a few days. Rhubarb will also produce a yellow stool. Stools. — Stools which are pale yellow when dis- charged, and which afterward become green, are often seen in disease. They may be themselves neutral or alka- line in reaction; this latter may, however, depend on the admixture of urine. An excess of bile may often cause very green stools. Brown Stools. — Brown stools may be due to changed biliary pigment and to drugs: e.g., bismuth causes the well-known dark stool. So also tannic acid and all iron salts give the dark stool, which varies from a deep brown to a black color. Blood in Stools. — Blood from the stomach or small intestine frequently gives the stool a black color resem- bling tar. Thus, a practical point in Boas's "Diagnostik der Magen- und Darmkrankheiten" is that, the brighter 70 "Verdauung im Sauglings-alter bei Krankhaften Zustanden," 'Jahrbuch fur Kinderheilkunde," B. 28, page 164. 2G4 INFANT-FEEDING. the color of the blood, the lower down near the rectum and anus must the pathological lesion be looked for; the darker the blood, the higher up must the cause be found: e.g., the diseased conditions exist in the stomach, duode- num, jejunum, etc., if the stool contain black blood. If the corpuscular elements of the blood are wanting, then the presence of blood can only be positively diag- nosticated by either a microchemical examination or by means of the spectroscope. The presence of red blood- corpuscles must always be regarded as a pathological factor. Brown Stools; Muddy Stools. — A brown stool in an infant is frequently caused by a diet of animal food or by a diet principally of broth. These stools have no distinct consistency nor reaction. In dyspeptic diarrhoea or in some forms of enterocolitis we have very offensive stools, and they resemble muddy water; with the latter there is considerable flatus during each movement. White or Light-Gray Stools. — White or light-gray stools usually are of a putty-like consistency, sometimes like dry balls on a diaper; sometimes they appear like ashes. Usually they are very offensive, consisting prin- cipally of fat. There is scarcely a trace of bile, or the latter may be absent altogether. Mucus.— Mucus is always present in all healthy stools, and is so well mixed with the stool that it does not appear as mucus to the naked eye. Any appearance, therefore, of mucus easily visible should be regarded as abnormal. Mucus is present in every form of intestinal disease : very abundant in inflammatory conditions affecting the large intestine, more so than in those affections of the small intestine, and especially so in inflammatory conditions of the colon, both acute and chronic. Jelly-like Masses. — Jelly-like masses of shreds of mucus, and cases where the stool consists chiefly of mucus, show that the affection is confined to the lower portion of the colon or that it is located in the rectum. INFANT-STOOLS. 2G5 Long Shreds of Mucus. — Long shreds of mucus, fre- quently resembling false membrane, are often found in catarrh of the large intestine. If the shreds of mucus are intimately mixed with the stool, then we must look for the lesion quite high up, and if it comes from the small intestine it is usually stained from bile. If the lesion is low down the mucus is not intimately mingled with the stool. Dyspeptic Stool. — The first change noticed in the dyspeptic stool is the increase of fat. Often the stool is quite green and contains small pieces, of yellowish-white color, which vary in size from that of a pin-head to the size of an ordinary pea. Hitherto, from their color, they were supposed to be casein lumps. Wegscheider has taught us that they consist principally of fat. Baginsky has shown that large colonies of bacteria are contained in these lumps of fat. Frequently they are so numerous that it looks as though the stool were composed only of these cheesy lumps. They can be easily differentiated from real casein lumps by their solubility in alcohol and ether. Fat Diarrhoea.— Biedevt and Demme have devoted considerable attention to this subject. 71 In some children the faeces showed 50 to 60 per cent, of fat, whereas the normal percentage in ordinary fasces varied from 13.9 per cent, (which is the normal quantity), according to Uffel- mann. Casein is not nearly as common an ingredient of fasces as is commonly supposed. Casein lumps can be seen in abundance in the course of a diarrhoea during an exclusive diet of milk. Quantity of Fwces. — The quantity of faeces varies, but it has been found that 100 grammes of milk-food will produce about 3 grammes of faeces, according to Baginsky. 71 See Biedert: "Fett-Dianhea/' in "Jahrbuch fur Kinderheil- kunde," 1878. 266 INFANT-FEEDING. This is a vital point, but I have found it very difficult to determine, for in most cases the napkins of the infants are soiled with urine plus the fasces, thus adding to the gross weight. Proteids. ■ — The proteids of milk are so thoroughly absorbed that only small traces of them can be found in the fasces. Normal milk-fasces contain large quantities of bacteria, but chiefly two kinds, previously mentioned, viz. : bacterium lactis aerogenes (Escherich) and bacterium coli commune. Other germs, especially those of the proteo- lytic type (i.e., those that render gelatin fluid), are not found under normal conditions. Albuminous decomposition and its products — tyro- sin, indol, phenol, and skatol — are not found in milk-fasces. But lactic acid, acetic acid, formic acid, and other fatty acids are present, causing the acid reaction. Saccharin Ferment.- — Von Jaksch found a saccharin ferment in the fasces of children. Peptonizing Ferment. — Baginsky found a peptonizing ferment also in infantile fasces. Escherich 72 says: "If albuminous decomposition with very foul offensive stools exists, these articles should be withheld from the diet and carbohydrates given, dextrin foods, sugars, and milk. If acid fermentation is present, with sour, but not offensive, stools, carbohydrates are to be withheld and albuminous foods given, such as animal broths, bouillon, peptones, etc. In the decomposition of milk, the sugar of milk, and not the casein, is usually broken up." Holt 73 says: "Regarding the exact indications accord- ing to which fat, sugar, and proteids of milk are to be varied, much remains to be learned." 72 "Jahrbuch fur Kinderheilkunde," "Beitrage zur Antiseptichen Behandlungs-methode der Magen-Darmkrankheiten des Sauglings- alters." 73 "Artificial Feeding," page 179. INFANT-STOOLS. 267 Sugar is Too Low. — If the sugar is too low, the gain in weight is apt to be slower than when furnished in proper amount. Sugar in Excess. — Symptoms indicating an excess of sugar: Colic or thin, green, very acid stools, sometimes causing irritation of the buttocks; sometimes there is re- gurgitation of food and eructations of gas. Excess' of Fat. — Excess of fat is indicated by the fre- quent regurgitation of food in small quantities, usually one or two hours after feeding. Sometimes an excess of fat causes very frequent passages very nearly normal in appearance. In some cases the stools contain small round lumps somewhat resembling casein, but really masses of fat. This has already been mentioned in speaking of the differentiation of true casein curds and small fat lumps by the solubility of the latter in alcohol or ether. Dry, Pasty Stools. — When too little fat is given, it is indicated by hard, dry, pasty stools, and usually constipa- tion. This can be easily remedied by the addition of cream three-fifths of which is fat. Holt speaks against increasing the fat above 4.5 per cent, in infants under six months old, and believes we should not go above 4 per cent. CHAPTER XL. Nathan Straus Milk-laboratories and Similar Charities. Since 1894, through the generosity of the Hon. Nathan Straus, pasteurized, modified, and natural milk has been supplied from laboratories and milk-depots scat- tered throughout New York City. Some of these are found in the different parks of the crowded portions of our city. Hundreds of thousands of bottles are dispensed annually in New York and in neighboring cities. Thus, in a report of the Board of Health of Brooklyn for the year 1895, we find that in Brooklyn 42,739 bottles were used. The infant-mortality has certainly been lessened dur- ing the last few years in these cities; a great deal of it is due to the education of the poorer classes living in tene- ment houses, by means of these laboratories, to the neces- sity of using boiled food, or call it sterilized milk, and boiled water. There are other factors which have less- ened the great infant-mortality in New York City. Let us not forget the difference in the cleanliness of the streets of this metropolis due to the energetic work of the late Colonel Waring. The weeding out of blocks of tenement-houses, and the substitution of small parks in the heart of the tenement-district must certainly be healthful. Whoever studies the development of rickets will find that it is not only the feeding, which is the prime factor, but it is the environment, the faulty dwell- ing, with its foul air and general unsanitary condition, that contribute to the poisoning of the air breathed by the infant; this poisoning is as distinct a toxcemic con- dition as it would be if a poison were injected directly (2G8) MILK LABORATORIES. 269 into the body. Faulty food, be it breast-milk or cows' milk, is the prime factor. Having been on continuous duty in the children's service of one of the largest clinics in this city for over ten years, the author has noted many, many changes. In recent years the large number of excursions, notably the St. John's Guild, which gives an excursion every day during the hot summer months to the poor destitute children of our city, has certainly added to the health of many little ones. There are also numerous sectarian ex- cursions; so, for example, there is a Hebrew sanitarium giving excursions to Rockaway every day during the summer. Then there are numerous church excursions and charitable funds, notably the New York Herald Ice Fund, all of which have a tendency to invigorate the lives of these poor infants, and in this manner they can withstand the terrible heat of the summer months, and survive it. The sanitary vigilance of the Board of Health of New York City has certainly improved the sewage and drainage, looked after the water-supply, and certainly benefited the city. These factors must be taken into account in studying the mortality and the population. The blessing for New York City will consist in giving it a pure, clean, and rich milk in which the stable, and cow, and milker's hands and all utensils are absolutely sterile. I cannot emphasize too strongly that the ideal milk of the future will not be sterilized milk, not pasteur- ized milk, but will be pure, raw milk. Nature, in the human breast, supplies her infants with raw milk at body- temperature; why must we feed our infants with boiled or steamed milk, especially so, when chemists have taught us that chemical changes take place in boiled as well as in sterilized milk, rendering the milk more indigestible than it was in its raw state? A vital point to remember is that the milk, when drawn from the cow, must be quickly cooled and must not be allowed to reach a temperature above 50° F. until used. 270 INFANT-FEEDING. Such milk will not permit the development of bac- teria dangerous to health. Rapid cooling, then, — to repeat again, — is as impor- tant as the most absolute assurance of cleanliness and ster- ility of every utensil brought in contact with milking — so necessary to avoid introduction of filth or bacteria. CHAPTER XLI. Colic. Colic is one of the most frequent causes of crying in children. They not only cry loudly, but will suddenly shriek, and when put to sleep will awaken with a sudden start, and cry loudly. The legs are usually flexed or they will move their legs back and forth, or up and down. They will seem to bend the body on itself. These attacks are usually associated with constipation; hence, it is a good plan, when the child is restless and utters a painful cry, to see if the bowels have moved. It is well known that this colic may be as well associated with diarrhoea. The origin of all colic is certainly the stomach. When dyspeptic conditions, arising from undigested particles of food in the stomach, exist, then fermentation, resulting in gas-formation, is the result. Colic is frequently known by the terms of "meteorismus or tympanites," but in the latter conditions the abdomen is greatly distended, and there is a permanent enlargement of it. Borborygmus can usually be made out, if the ear is applied to the abdomen. The vast majority of cases of colic have their seat in the intestine, and can be relieved very quickly. Worms (ascarides) have been known to cause colic. Besides, when there is a general loss of tone on the part of the muscular layers in the walls of the intestine, colic will frequently result. Jacobi believes that colic can be caused by chronic peritonitis resulting in adhesions or local changes in the walls of the intestine that will pro- duce local contractions or dilatations. An excellent preparation to relieve colic is calcined magnesia, or milk of magnesia, made by Phillips. Hare's "System of Medicine" contains an article by Stewart ad- (271) 272 INFANT-FEEDING. vocating its use. It has served the writer very well espe- cially in young infants, where acidity was prevalent. A half-teaspoonful several times a day was enough in some cases, while others required several teaspoonfuls during the day. It is valuable where constipation exists, and can be added to the bottle of food. The treatment of colic is simple when the cause is known. The quickest method of relieving colic is to give an enema of soap and water or of warm chamomile- tea. I usually take an ounce of German chamomile- flowers and steep them in a quart of boiling water for from ten to fifteen minutes, then strain. The injection is to be given in the same manner as will be described in detail in the chapter on constipation. My method is to allow 1 or 2 pints of chamomile-tea at a temperature of 100° to 110° F. (no hotter) to flow slowly into the rectum, and by all means the colon. When the colon is thor- oughly flushed with this warm tea, and emptied of its fseces, it is usual for the attack of colic to cease. In addi- tion to washing the colon, it is a good plan to apply a small bag of either chamomile-flowers or slippery-elm bark, or ground flaxseed meal. To do this, I make a bag of cheese-cloth, capable of holding from 1 to 2 ounces, and then fill it with one of the above-mentioned ingre- dients; sew the bag shut when filled, and heat it before applying to the abdomen. Several of these bags can be made and kept in readiness, so that they can be applied quickly. It is a good plan to have one heating on the stove, while another is on the abdomen. These little bags are very grateful, and we are frequently rewarded by having the infant not only expel wind shortly after they are applied, but also frequently fall asleep. MASSAGE. During an attack of colic gentle massage with warm sweet oil or melted vaselin or lard will certainly be very comforting to the child. My plan is to take a bottle of colic. 273 oil, warm it by placing it in a kettle of warm water, and then to pour it on the abdomen. The distended abdomen should then be thoroughly kneaded, and the gas expelled. Then the warm applications mentioned above can be ap- plied. DRUG TREATMENT. If the colic originated from a fermentative dyspep- sia, then treatment must be directed to the stomach. For this purpose antifermentatives, like the mistura rhei et sodas, should be given in doses of 1 / 2 to 1 teaspoonful, diluted with water, every two or three hours until there is a thorough evacuation. Very good results will be found, after the bowel has been cleaned with the quart of chamomile-tea previously mentioned, by administering from 5 to 10 grains of bismuth; I prefer to use beta- naphtol or the subnitrate; a / 2 -grain doses of resorcin will also be found useful. Paregoric, in doses of 15 drops to 1 / 2 teaspoonful should be administered with great cau- tion to children of six months or older. It is understood that no physician will forget the danger of giving re- peated doses of paregoric or permitting the same to be administered by incompetent people not aware of the dangers of the drug habit. The author has not only seen distinct opium poisoning follow the use of paregoric, but has also had occasion to see the distinct opium habit in very young children. This was reported by the author in a paper read before the ISTew York County Medical Society, January 22, 1894, which was published in ex- tenso in the Medical Record of February 17, 1894. For an infant during the first few months, it is hardly safe to give more than 5 drops of paregoric, repeated in an hour if there is no relief. Another drug that has served the author very well is Hoffmann's anodyne in doses of from 1 to 5 drops, repeated in an hour if necessary. For an infant up to two months 1 drop per dose; from two to four months, 2 drops per dose; four to six months, 3 274 INFANT-FEUDING. drops; six to nine months and until one year of age, 4 drops; children from one to two years, 5 drops. This is to be given in a teaspoonful of sterilized water. Another valuable drug, and one that is to be given cautiously, and in the same doses as Hoffmann's anodyne, is spirit of chloroform; never should more than from 1 to 4 drops be given to a child up to one year of age, and younger children less in proportion. I cannot favor the admin- istration of nauseating or foul-smelling drugs, such as asafcetida. We must try to cater to an infant's taste, especially so when in pain. THE USE OF SUGAR. When colic is caused by an excess of sugar, there will be considerable eructations of gas, and, frequently, small quantities of food will be regurgitated. The stools, when an excess of sugar is given, are thin and greenish, smell very- acid, and usually produce a red- dened excoriation of the buttocks afound the anus. When children show a tendency to the development of gas and have constant recurring colic, my plan is to discontinue the use of sugar until such time as this fermentation is absent. To sweeten the food I use small, saccharin tablets, 1 grain being ample to sweeten 1 pint of food. When there is a tendency to constipation, it is possible not only to sweeten the food, but also to modify this constipation by adding 1 teaspoonful of pure glycerin to each bottle of food prepared. A teaspoonful of malt- extract will also relieve constipation. EXCESS OF PKOTEIDS. A careful observation of the stools would easily show whether the albuminoids are in excess, for they are usually present in the form of curds. This condition is usually associated with constipation, and the indication would be to cut down the quantity of curd administered. CHAPTER XLIL Constipation. To consider the cause of constipation during the nursing period let us first look into the mechanical cause: Concetti, 74 in a very elaborate article, gives the various anatomical reasons for constipation. He states that Huguier, in the Bulletin cle V Academie de Medecine, had reported this same pathological condition several years prior to Jacobi, of New York. Thus, Huguier advises, as a practical point, that when a colotomy was to be per- formed in an infant it would be wiser to perform the same on the right side rather than on the left. He stated that it was much easier, owing to the greater number of flexures, to reach the same by operating on the right side in cases of atresia of the anus. Concetti further states that Jacobi, in 1868, reported in the American Journal of Obstetrics an elaborate article, which has since appeared in the "Therapeutics of Infancy and Childhood" (A. Jacobi, 1887), giving the anatomical reasons in detail. They are well worth noting: — The embryonic intestine is formed in separate di- visions. There is no ascending colon up to the fourth or fifth month of foetal life. It is very short in the mature newborn. Despite this, the large intestine of the mature foetus is longer in proportion than that of the adult. It is three times as long as the body of the foetus, while it is only twice as long in the adult. There is the same disproportion with regard to the length of the small intestine. The small intestine of the foetus in the ninth month is twelve times as long as its 74 Archiv fur Kinderheilkunde, vol. xxvii, 1899. (275) 276 INFANT-FEEDING. body. The small intestine of the adult is only eight times as long as the body. The colon ascendens being very short, the surplus of length, particularly as the transverse colon also is not long, belongs to the descending colon, and especially to the sigmoid flexure. Drandt found it between 8 and 24 centimetres in length, averaging from 14 to 20. I have seen a case in which it was 30 centimetres long. As the pelvis is very narrow, the great length of the lower part of the large intestine is the cause of multiple flexures, instead of the single sigmoid flexure of the adult. Thus it is that, now and then, two or even three flexures are found, and to such an extent that one of them may be found to extend as far as the right side of the pelvis. Cruveilhier and Sappey speak of this position of the lower part of the intestine in the right side of the pelvis as an anomaly. Huguier finds it on the right side of the body in the majority of cases. Others only occasion- ally, although they admit the great length of the sig- moid flexure. In common with Huguier, who even proposes to operate for artificial anus in the right side, I have found one of the flexures on the right side many times. The great length of the large intestine and the multi- plicity of its flexures are of great functional importance. At all events, they retard the movement of the intestinal contents, facilitate the absorption of fluids, and thus the faeces are rendered solid. .When this length is developed to an unusual extent, constipation is the natural result. In the American Journal of Obstetrics, August, 1869, I have described two cases in which the descending colon was so long that the diagnosis of imperforate rectum was made. In one of them the operation for artificial anus was performed. Such cases and such errors are certainly very rare ; still there are those in which normal anatomical conditions will lead to incidents of great pathological im- portance. CONSTIPATION". 277 Other cases of constipation in the infant may be classed under four heads: — - First. — The intestinal mucus is deficient or too vis- cid. Such is the case in febrile conditions, now and then in chronic intestinal catarrh, and also when there is too much perspiration and secretion of urine. Second. — Improper condition of food. A super- abundance of casein, particularly cows' casein; of starch; the absence of sugar, and the administration of astrin- gents and iron. Third. — Incomplete peristalsis, such as exists in the rachitic debility of the muscular layer, in the muscular debility dependent upon sedentary habits and peritonitis, intestinal atrophy, and hydrocephalus. Fourth. — Mechanical obstruction. Cystic tumors in the intestine. There is, further, intussusception and twist- ing of the intestine, incarcerated hernia, even umbilical hernia, hardened faeces, and imperforations. In all these cases the diagnosis should not be made without manual examination. In most of the cases the abdomen is inflated, though it be painless. The fasces come away in small, hard lumps or in large masses. The liver and spleen are displaced. The liver may be so turned that a part of its posterior surface comes forward. The abdominal veins are enlarged to such an extent that they form circles around the umbilicus, similar to what is seen in hepatic cirrhosis. These children lose their appetite, sometimes vomit, and the irritation produced by the hardened masses in the intestinal canal may be such as to finally result in diarrhoea, which, however, is not always sufficient to empty the tract. There is, besides, an apparent constipation, which should not be mistaken for any of the above varieties. Now and then a child will appear to be constipated, have a movement every two or three days, and at the same time the amount of fasces discharged is very small. This apparent constipation is seen in very young infants rather 278 INFANT-FEEDING. than in those of more advanced age. Snch children are emaciated, sometimes atrophic. They appear to be con- stipated because of lack of food, and not infrequently this apparent constipation is soon relieved by a sufficient amount of nourishment. Constipation resulting from a superabundance of starch in the food is easily cured by the withdrawal of the latter. Constipation produced by too much casein in the food will be relieved by diminishing its quantity. The propor- tion of casein in the food of infants should never be more than 1 per cent. Besides, this amount of casein ought to be copiously mixed with a glutinous decoction. Infants that have been fed on starchy food or even such cereals as barley, should have oatmeal substituted for the barley. Constipation depending on lack of sugar is very often speedily relieved by increasing the quantity of sugar in the food. This is the case, not only in artificial feeding, but also when the children are fed normally on breast- milk. Such mothers' milk as is white and dense, and contains a large amount of casein, is made more digestible, and will produce better evacuations, when a piece of loaf- sugar dissolved in tepid water is given immediately before nursing. As there is frequently a large excess of acid in the intestine, magnesia with or without rhubarb, will fre- quently relieve the acidity and cause a movement of the bowels. In a previous section on "Cream" I have already spoken of the deficiency of fat, which is one of the most frequent causes of constipation. Hence, in an infant nursing at the breast it is wise to give the child a tea- spoonful of raw cream immediately before taking the breast to correct the constipation. Cream consists of so much fat that in this manner we add fat directly to our food. This is the secret of success attained by some CONSTIPATION. £79 authors when they advise giving codliver-oil, butter, olive-oil, or fried bacon to very young children. Each one desires to remedy the deficiency of fat in his own particular manner. A DBINK OF WATEK. From infancy, when the child is but a few days old, we should make it a rule to give it a drink of water; thus a very small infant during its first week can be given two to three teaspoonfuls of boiled water during the day. A safe plan is to give this drink of water when it is not time for feeding, and if the child appears restless. It is understood that we must first satisfy ourselves that the child has not had a stool, is not lying in a soiled napkin, and that other conditions — such as colic — do not cause uneasiness in the baby. When a child is several months old, the quantity of water can be increased from teaspoon- fuls to as _ many wineglassfuls. Frequently have I noted the disappearance of a continued constipation after giving an infant its "drink of water" regularly. IMMEDIATE RELIEF OF CONSTIPATION. A rule that I have always followed, and one that I lay stress upon, is never to allow a child to retire at night without having had a movement of the bowels during the day. The reason for this is plain; not only will the accumulated fasces and gas cause flatulence, colic, and uneasiness, but this constant distension of the bowels will dilate the intestines to such a degree that frequently a permanent pendulous belly remains. My plan is to order an injection of a half -tumbler of ordinary glycerin mixed with a pint of warm water, — temperature, 100° F., — and to allow this quantity to flow into the rectum by using a fountain-syringe, the end of which has the smallest infants' rectal nozzle. In this manner we have a rapid emptying of the rectum and 280 INFANT-FEEDING. colon, and can be assured of temporary and possibly per- manent relief. It is not absolutely vital to use glycerin and water, for a similar result can be obtained if we make soap-water by rubbing up a piece of Castile soap with a pint of warm water, or using glycerin soap with the equal quantity of water, if the latter soap can be pro- cured. Continued Use of Enema. — In obstinate cases it is well to slip a soft-rubber rectal tube over the nozzle, and, having anointed the rubber tube with vaselin or glycerin, the same can be pushed slowly into the rectum, then allow about half a pint of water to flow into the rectum, which will distend it gradually, and, by simply pushing the tube farther into the colon, we can allow the balance of 1 pint or more to flow directly into the colon. The continued use (daily) of these enemas is not fraught with danger; on the contrary, these rectal injections can be used for months. In safe hands, if the mother or nurse is intel- ligent, there should be not only no injury, but positive good, from its continued use. REMOVAL OF SCYBALA. Hardened round balls or fragments of fseces will fre- quently be caused when the stool remains very long in the colon, or when the sigmoid flexure has an unusual length; in such instances the injection of either * / 2 pint of lukewarm sweet oil or glycerin will soften these scybala and aid in their expulsion. At times these balls will be as hard as marbles, and may require the aid of a small scoop (a very small teaspoon will do) to aid in their removal. DRUG TREATMENT. A great many drugs are indicated and contra-indi- cated in the treatment of constipation. The intelligent practitioner does not desire merely one movement of the bowels, brought about by drugs, but seeks rather to use Fig. 45.— Funnel-shaped Depression of Sternum. Rachitic Ky- phosis. Deformity of Spine. Picture also Illustrates Ra- chitic Square Head. (From Author's Service in Children's Department of German Poliklinik.) CONSTIPATION. 281 such therapeutic measures as will give a permanent cure. My choice of drugs is the following: — I£ Ext. cascara sagrada fl., §j. Glycerin, 3j. Mix. Twenty drops of the above mixture in a teaspoonful of water three times a day, for children about three months old. At the age of six months, double the dose, or 20 drops three times a day. At the age of one year a teaspoonful three times a day. Another valuable preparation is malt-extract with cas- cara, in teaspoonful closes, once or twice a day. My plan is to give the first dose in the morning be- fore the feeding, and note the result. If the bowels move by noon-time then I discontinue the dose at noon, and give a second dose in the evening. If, however, there is no effect by noon-time, then I continue my second dose, and follow with my third dose in the evening. Thus, it will be apparent that, if one dose answers for the day, then we should discontinue the medicine for that day, but commence again on the following day, and keep up this form of drug treatment until it is apparent that the bowels are not as sluggish in their action as before. An- other drug which has been one of my stand-bys for many years is mix vomica. I give 1 drop of the tincture of nux vomica in a teaspoonful of sterile water three times a day, for an infant up to one year of age. Chil- dren of two years I give 2 drops three times a day. From three to six years, 3 drops three times a day. Six to ten years, 4 drops three times a day. Ten to fifteen years of age, 5 drops three times a day. ]STux vomica is always to be administered on an empty stomach; in other words, before feeding. Another valuable drug is rhubarb in the form of the aromatic syrup of rhubarb. From 1 / 2 to 1 teaspoonful once or twice a day, repeated every two days, will frequently afford relief. Powdered rhubarb and magnesia, given in teaspoon- ful doses to very young children, is one of the best laxa- 282 INFANT-FEEDING. tives and antifermentatives that we possess. It is espe- cially indicated for the relief of colic. Citrate of magnesia, given in wineglassful doses to children over one year of age once or twice a day, can also be recommended. In atonic conditions of the bowels depending on gen- eral weakness, strychnine, given in V200 grain doses twice a day, will be found useful. This may or may not be com- bined with iron. The infusion of senna-leaves is made by boiling a heaping teaspoonful of ordinary senna in a teacupful of boiling water for fifteen minutes, straining, and when cool adding 1 tablespoon of glycerin to 5 tablespoons of this infusion of senna. This quantity to be adminis- tered in three doses at intervals of four or five hours. In some instances the addition of syrup of manna will be found advantageous in sweetening the infusion of senna. Certain drugs should not be given. Of these castor- oil may serve as a type. The constipating effect following the use of castor-oil is so well known that this drug is indicated when we wish to cleanse the stomach and bowels and remove stagnant food, as, for example: in fermenta- tive dyspepsia accompanied by diarrhoea. Thus, we not only have an effective movement, but a constipating effect following the same. The use of drastic cathartics — such as scammony, elaterin, or podophyllin — should not be thought of in the treatment of infants and children. Very rarely do I use aloes, owing to its offensive taste. It is understood that calomel is only to be given when we wish to cleanse and produce an antiseptic effect in the intestine; for the treatment of constipation per se, calomel is entirely out of place. Suppositories. — Among those most commonly used are suppositories of the glycerin and gluten type. Gluten suppositories are made by the Health Food Company, of New York City. Most suppositories in the market are Fig. 46. — Rickets, showing Beaded Ribs. Breast-Fed Infant with Poor Hygienic Conditions and Delicate Mother. (From Children's Service of German Poliklinik.) CONSTIPATION". 283 entirely too large, and frequently must be cut into halves and quarters. The suppository made by Parke, Davis & Co. has served the author very well. It should be dis- tinctly understood that a suppository is to be used in the evening for the same relief as we desire from the injection or enema previously mentioned. Neither the suppository nor the injection should be used with the idea of curing a constipation. MASSAGE. Continued kneading of the abdomen with the aid of vaselin or oil will be found serviceable, and, if properly done, will provoke an action of the bowel. Thus it is that rubbing the abdomen with castor-oil has frequently been recommended in the treatment of constipation; the effect supposed to be due to the castor-oil is, in reality, due to the massage, and to nothing else. "When massage is used, it should be continued from five to ten minutes every day for one month, morning and evening. This will certainly aid and stimulate peristalsis, and ultimately tone the muscles and cure the constipation. ELECTRICITY. This is very valuable to stimulate peristalsis. The faradic, galvanic, or static current can be used. For the general practitioner the use of the galvanic current, five to ten cells, is sufficient. The negative pole (cathode) should be applied in the rectum, and the positive pole, which produces peristaltic waves, should be applied over the ascending, descending, and transverse colon. Local contractions result from the negative pole. A gentle faradic current applied over the spine and the abdomen will answer if used for several minutes in the absence of the galvanic current. Galvanic electricity should be used every day; frequently months are required to insure a cure, in conjunction with the medicinal and dietetic treatment. 284 INFANT-FEEDING. DIETETIC TREATMENT, We have previously mentioned the value of cream, and the addition of water for the treatment of consti- pation. In bottle babies it is well to remember that oat- meal-water and sago-water should be used when constipa- tion exists. Under no condition should barley or rice be given, as the latter will simply increase the constipation. Older children should be given fruit, baked apples, peaches, prunes, grapes, and oranges, and avoid pears. Buttermilk will be found serviceable, as well as koumiss, for the relief of constipation. Sugar (cane-sugar) will be found quite serviceable, when added to water, for the relief of constipation in nursing or bottle-fed babies. Thus, a good plan, according to Jacobi, is to give a small piece of loaf-sugar dissolved in water immediately before nursing, and to substitute and use cane-sugar instead of milk-sugar for bottle-fed babies. Having regulated the diet and excluded fresh bread, cakes, pies, pastries, macaroni, and other floury foods, we should insist, in children over two years of age, on eating- all green vegetables with the exception of cabbage, beans, turnips, potatoes, and corn. Thus, celery, spinach, green peas, asparagus, and cauliflower are recommended. EXERCISE. What massage is for a young infant exercise is for an older child. Thus, it is apparent that atonic condi- tions can best be relieved by combining the dietetic and medicinal treatment with out-of-door exercise. Children should be permitted to romp about and walk and play out of doors, but not to a point approaching fatigue. Older children will find bicycle exercise or horseback- riding decidedly beneficial. It is important, however, to regulate the amount of such exercise, and thus it is ap- parent that it is the physician's duty to tell the mother or nurse just how long a child should be permitted to Fie-. 47. — Showing Rachitic Beaded Ribs on Left Side of Thorax. CONSTIPATION. 285 exercise. It would seem that one-half hour twice a day is ample to arrive at beneficial results. Overindulgence in such sports will frequently result in rupture and pro- duce heart-strain. In cardiac lesions, in asthmatic con- ditions, if children suffer with whooping-cough, and in tuberculous conditions such exercises must not be allowed. HYGIENIC TREATMENT. We should insist on proper ventilation of a child's sleeping-room at night, and it is, therefore, advised that the window be left open a few inches. This is not fraught with danger; on the contrary, it is healthful and bene- ficial to allow children to play in the open air all day, and naturally to shut them up in poorly ventilated apart- ments at night is simply inviting both throat and lung trouble. In addition to proper ventilation, bathing in cool water or lukewarm water, followed by an abdominal spray or a douche directed against the stomach and bow- els, will be found advantageous in the correction of this ailment. Following the bath, friction with a good, coarse, Turkish towel will be found useful. My preference has always been for a lukewarm bath, followed by a cold douche for a few moments, every morning, and then to have the child properly rubbed until the skin is reddened with a Turkish towel, followed by massage with oil or vaselin. CHAPTEE XLIII. Statistics. The recorded births of tlie three years 1890, 1891, and 1892, according to the New York Board of Health, were 135,602. It is estimated that this represents only five-sixths of the actual number born; so that 162,721 would really represent the actual number of births for this period. During the same time the number of deaths of children under five years of age were 52,213, representing over 32 per cent, of the whole number of births. In July, 1893, the deaths of children under five years of age numbered 2796. During the same month of 1894, 2562. In August, 1893, there were 1686. In August, 1894, 1559. During eight months ending in August the deaths under five years of age were: 1895, 13,287; 1896, 12,734; 1897, 10,962. During June, July, and August of 1896 there were 5671 deaths. During the same period of 1897, 5041. In 1897 and in 1902 we had a cool sum- mer. The following tables, compiled from the vital statis- tics of the Board of Health, show the relative death-rate and the infant-population in (old) New York City. Deaths and Death-eates op Children under Five Years oe Age, for the Months of June, July, and August. Tear. Population. Deaths. Death-rate. 1891 188,703 5,945 126.0 1892 194,214 6,612 136.1 1893 199,886 5,892 117.9 1894 205,723 5,788 112.5 1895 212,983 6,183 116.1 1896 216,728 5,671 104.7 (286) STATISTICS. 287 Year. Population. Deaths. Death-rate. 1897 220,641 5,041 91.4 1898 224,736 5,047 89.8 1899 229,029 4,689 81.9 1900 ...;.. 233,537 4,562 78.1 1901 238,279 4,642 77.9 1902 243,500 4,387 72.1 Population, Deaths, and Death-rates of Children Under Five Years of Age from 1891 to 1902 in (old) New York City. Year. Population. Deaths. Death-rate. 1891 188,703 18,224 96.6 1892 194,214 18,684 96.2 1893 199,886 17,865 89.4 1894 205,723 ■ 17,558 85.3 1895 ...... 212,983 18,221 85.6 1896 216,728 16,807 77.5 1897 220,641 15,395 69.8 1898 224,736 15,591 69.3 1899 229,029 14,391 62.8 1900 233,537 15,648 67.0 1901 238,279 14,809 62.1 1902 243,500 15,019 61.7 As the census authorities have not yet supplied the figures of the number of children living under five in our city, the above population represents an estimation based on the supposition that the same proportion of children under five to total population exists to-day as existed in the census of 1895 : 75 to wit, 11.37 per cent. The author desires to thankfully acknowledge the kindness of Dr. "William H. Guilfoy, of the New York Health Department, in furnishing the above statistics. 75 According to the census of June 1, 1900, 11.46 per cent. CHAPTER XLIV. Rachitis (Rickets). Prof. Paul Zweifel, in his recent work (1900) on the above subject, says: "That the addition of water to raw milk aids in the digestion of the same, whereas the addition of an equal quantity of water to boiled milk produces just the opposite effect." Thus it would ap- pear, from the experiments of this author, that raw cows' milk diluted with an equal quantity or even more water will be much more easily assimilated than diluted boiled milk. Zweifel agrees with Schlesinger, of Breslau, "that the addition of water to milk does not render it more digestible." Clinical investigations by such authorities as Professor Baginsky, in Berlin, have proved conclusively that whole milk (undiluted) cannot be fed to infants with weak digestive powers or those suffering with dyspepsia without aggravating the dyspeptic conditions and threat- ening the very existence of the child. Time and time again has the author tried to increase the weight of chil- dren and to strengthen them by giving them more con- centrated food. These experiments would have proved disastrous in winter but for the rapid withdrawal and substitution of the requisite diluted milk solution neces- sary for the age of the infant. THE ADDITION OF TABLE-SALT. The addition of table-salt has given such satisfactory results when added to milk that Zweifel insists on its ad- vantage -in preventing rickets. When a large-size thimble is tilled with salt it will hold about 3 grammes. The smaller thimbles will hold about 2.5 grammes of salt. If (288) RACHITIS. 289 this quantity (3 grammes) of table-salt is added to 1 pint of water (500 cubic centimetres), then we have a solu- tion approximating the decinormal salt solution commonly known as -the physiological normal salt solution. Zweifel maintains that both sterilizing and boiling the milk, ac- cording to the Soxhlet method, does not render it more indigestible. On the other hand, he believes that the albuminoids of the milk are rendered more difficult to digest, and thus he believes that boiling might be a factor in producing rickets. Rickets is caused by the substitutes for milk rather than by milk itself. When children are improperly fed so that the body is underfed, muscle- and bone- formation will be slow. Thus it is that the eruption of the teeth will be delayed, and this is one of the most prominent symptoms of rick- ets. The bones show the most characteristic result of improper nutrition, for they are very soft and spongy. They will yield to the weight of the body if used in walking, and thus it is that bow-legs with extensive curva- tures form such a prominent feature in showing the result of using soft bones. The most typical symptoms can be studied on the head and spine. Thus, craniotabes can be explained by a deficient nutrition in which the cranial bones will be found so soft that they will yield to the pressure of the thumb. The cranial bones will frequently be found to be as soft and as thin as pasteboard. The spine is most frequently deformed, and will show a typical rachitic kyphosis. CAUSES. The majority of children suffering with rickets are or were bottle-fed children. Thus, it is apparent that no food can equal or east-feeding, he it mother or wet-nurse, in preventing rickets. There are a great many other causes, such, for example, as bad sanitary measures and faulty hygiene. Breast-fed children will sometimes show 290 INFANT-FEEDING. rickets when they have been living in bad apartments, breathing foul air, and not being properly cared for. One of the most frequent causes of rickets is "prolonged" nurs- ing. In the section on "Breast-feeding" I have already pointed out the necessity for making a proper chemical examination of the breast-milk if the infant "shows no increase in weight." We know that, toward the end of lactation, not only do the proteids diminish, but get to such a low percentage that, unless we combine hand- feeding by adding the raw white of egg, steak-juice, and other proteids, like the cereals, to the nursing, the child will be underfed. This underfeeding is certainly a con- tributing factor, both to the causation and leading to the development of rickets. Children that have suffered prolonged diarrhoeas or with severe diseases — like dysentery, typhoid, bronchitis, and pneumonias — are prone to the development of rickets. Children of syphilitic parents and whose parents are tu- berculous are more prone to the development of this disease. Von Bitter, quoted by Professor Baginsky, says that, in twenty-seven cases out of seventy-one examined by him, rickets was not only found in the children, but as well in the mothers of these same cases. Thus it is that Kassowitz and Schwarz 76 have mentioned the exist- ence of congenital rickets. This same author found that 80 per cent, of children born in the Vienna Lying-in Hospital were rachitic. This statement is not so easily accepted, however, for neither Professor Baginsky nor Virchow accept the same. Experimentally, it has been found as long ago as 1842 by Chossat that when lime is deducted from the nourishment of young animals not only soft bones result, but they finally die. Heitz- mann maintains that, if lactic acid is introduced into the food of young animals, the result will be, first, rickets, and, later on, osteomalacia will result therefrom. Clin- 'Wiener medicinische Jahrbucher," 1887, vol. viii. RACHITIS. 291 ical investigations have shown that cases of rickets occur more often during the winter months; thus it is ap- parent that improper ventilation is one of the most ex- citing causes of this disease. The prognosis of infants suffering with rickets depends upon the amount of damage already done. If deformities of the spine, of the head, of the legs, and arms exist, careful orthopaedic treatment will certainly modify the condition. The backbone of the treatment will, how- ever, consist in studying "the dietetic requirements of the case." In this disease more than in any other will the advantages of a carefully regulated diet be apparent, if the hygienic factors and proper medicinal treatment are included. Rachitic children require milk, meat, and eggs ; plenty of cereals, like wheat, barley, rice, farina, sago, oatmeal, hominy; they require butter, and, if they will not take butter, then codliver-oil or lipanin; iron will be found valuable, as well as Fellows's hypophosphites ; malt-extract and ferrum lacticum are indicated. Great emphasis must be put on the value of fresh air and sunshine in the treat- ment of this disease. EXTERNAL TREATMENT. Bathing in sea-salt, taking 1 to 2 pounds of salt to a bath-tub of water, to which malt-extract, about 1 teacup- ful, is added; in the place of malt Baginsky advises 2 ounces of calamus-root. I have seen very good results follow the continued use of bran and sea-salt, of which 2 to 3 pounds of bran and a pound of sea-salt are placed in a bag made of cheese-cloth. This bag is put into the bath-tub one-half hour before putting the baby in it. Enough water is then added to bathe the child ; the tem- perature of the bath should be from 80° to 100° F., my preference being for a cool bath, really tepid, temperature of 90° F. ; duration of bath, from 5 to 10 minutes, fol- lowed by a good, brisk rub with a coarse Turkish towel. 292 INFANT-FEEDING. Massage of the muscles aided by passive movements will be found very valuable in producing a better mus- cular development, aiding metabolism, and stimulating the circulation in general. The great susceptibility of rachitic children to colds and coughs, especially to croup, can certainly be modified if such children will be given cold baths, cold sponging, cold spray, or a cold douche. Such children should not be overbundled with clothing, and while I insist on protecting the lungs and the whole body from sudden changes in the weather, the use of too much clothing will certainly tend to increase the amount of perspiration, and thus add to, rather than mitigate, our trouble. INTERNAL TREATMENT. Kassowitz Formulae. — 1. F* Phosphori puri, 0.01. 01. amygdal., 70.00. Sacch. alb., 30.00. JEiher. fragar., gtt. xx. 2. R Phosphori puri, 0.01. Solve in ol. amygdal. dulc, 10.00. Pulv. gunimi arab., 5.00. Sirupi simpl., 5.00. Aq. dest., 80.00. 3. B Phosphori puri, 0.01. Ol. amygdal., 30.00. Pulv. gumnii arab., 15.00. Sacch. alb., 15.00 Aq. dest., 40.00. Of the above mixtures, 1 to 2 teaspoonfuls per day; so that children would receive x / 2 milligramme (0.0005) of phosphorus, and in prescribing 100 grammes of cod- liver-oil or in the emulsion containing the above-men- tioned dose of phosphorus the quantity would last twenty days. Formula 'No. 1, given by Professor Kassowitz, of Vienna, does not mix well; neither does Formula 3; so that Formula 2 is the only one available for practical Fig. 53. — Athrepsia Infantum. RACHITIS. 293 purposes, and may be used. A chemical test for the presence of phosphorus will always yield a positive result. Thus far the specific action of unoxidized pure phosphorus has not yet been proved. In fact, such keen observers as Baginsky and Henoch do not believe that phosphorus in its pure state is applicable. A very valuable drug in the treatment of rickets is the following: Glycerophosphate of lime, in doses of 1 to 5 grains for an infant one year old, to be given im- mediately after feeding. For a child six months old one- half the dose. When this disease is associated with anaemia or very great weakness or where it is desirable to tone up the general system, then add to the glycerophosphate of lime an equal dose of the glycerophosphate of iron. This drug treatment should be continued for several months before expecting results. It is understood that the author insists on a radical change of diet, and also the strictest hygienic treatment, when possible. All factors will be more es- sential than merely giving an infant a few doses of drugs. OHAPTEE XLV. Scurvy (Scorbutus). This is a constitutional disease resulting from im- proper feeding. It usually occurs before the end of the second year, and rarely occurs before the first six months of a child's life. As in adults, scurvy is found when fresh food has been withdrawn from the dietary. It is natural, therefore, to look for scorbutic cases among children who are : — First. — Deprived of breast-milk. Second. — In those brought up exclusively on milk which is devitalized by prolonged sterilization. Third. — It is found in children brought up on con- densed milks and proprietary foods to which fresh milk has not been added. There seems to be, therefore, a direct relationship between the absence of fresh milk, be it cows' milk or human milk, and the development of this disease. Profound ansemia and tendencies to haemorrhage usu- ally are the most prominent symptoms. The most im- portant symptoms are, according to Starr: First, immo- bility, progressing to pseudoparalysis; intense hyper- esthesia and general swelling, situated most frequently in the legs, but not limited to these members; the in- vesting skin is shiny and tense, but there is neither oedema nor local heat; the subsidence of the general swelling reveals deep fusiform thickening about the shafts of the long bones, in the neighborhood of the joints. In extreme cases there is a tendency to fracture near the epiphysis. Second, the gums about the erupted teeth are swollen, and purple in color, and in marked cases become spongy and readily bleed. Third, the rapid disappearance (294) Fig. 54. — Athrepsia Infantum. SCURVY. 295 of all symptoms upon the institution of a proper anti- scorbutic diet. This disease is liable to occur in either sex; it is not influenced by climate or locality; it is found as well in the best as in the poorest hygienic surroundings. By far the greatest number of cases is found among the rich. It is evident that this disease is due to improper feeding more than to an improper hygiene. Some authors believe that this disease is caused by a specific micro-organism; this latter fact has not yet been definitely settled. It is interesting to note the various views expressed by competent observers upon this subject; thus, while a large majority of clinicians hold that sterilized milk per se does cause scurvy, Eotch states that it does not, in his own experience, seem to do so. Starr maintains just the reverse of Rotch, and believes that sterilized milk is a causative factor. From my own experience I quite agree that sterilized milk — especially the prolonged sterilization, by which the albumins are changed, and by which this prolonged heating causes devitalization, which is so inim- ical to successful feeding — is a causative factor in this disease. It is peculiar that scurvy will be cured by giving raw milk, fresh fruits, and acid fruits; yet still we find that a great many clinicians persist in prescribing sterilized milk until either rickets or scurvy is established. It was for this reason that at a discussion on infant-feeding at the Academy of Medicine, October 18, 1900, 1 was led to in- sist on the use of raw milk as the proper means of feeding children. Raw milk possesses certain advantages over boiled milk; it is more readily assimilated and the proteids are not so difficult to digest. It is a well-known fact that boiled milk and sterilized milk have a tendency to produce constipation, whereas the opposite is true of raw milk. Improper infant-food has additional disadvantages when it is subjected to excessive heating. The large num- 296 INFANT-FEEDING. ber of failures with milk modified at a laboratory are not so much dtie to the process involved in the modification as to the amount of heat that the food is subjected to prior to being imbibed. Where milk is modified for infant-feeding, using raw milk only, I have never seen constipation; the reverse, however, has always been true when milk was modified and then subjected to sterilization. The vital point has always impressed me as being, not so much to sterilize milk after it has been drawn from the cow, but to apply the principle of sterilization to the stable, the cow, the utensils, the milker's hands, and to everything coming in contact with the milk from the time it leaves the cow's udder until it is fed to the baby. When oatmeal-gruel or barley-gruel is given with an in- sufficient quantity of cows' milk and then fed for a long time, we must not be surprised to find a case of scurvy. When pro- prietary foods are given without the addition of fresh milk, then scurvy will usually result. When cream-mixtures are given which are deficient in fat and proteids, then scurvy may result. Thus we find that the true, underlying cause of scurvy is starvation due to deficiency of one or more nutritive ele- ments in the food given. The following case of scurvy will illustrate the con- dition : — A child, 13 months old, was brought to me with a history of being very restless and having lost considerable Aveight. The child showed a shriveled appearance of the skin; its normal elasticity Avas gone; the skin Avas dry; the thorax was pigeon-breasted; the arms and legs Avere thin; both arms and legs showed marked ten- derness on the slightest motion; there was baldness at the occiput, and the anterior fontanelle Avas not closed; the child had eight teeth, all of which were slightly carious; the gums around the teeth were deeply congested and showed bluish ridges; the gums were spongy and bled very easily; there was an intense foetor to the breath; the child had been suffering from diarrhoea for the past two months, with occasional periods of constipation; there Avas no vomiting; the appetite had always been very poor. The previous history of scuevy. 297 the child was that, when born, it weighed about 5 pounds ; it was very small at birth. The mother of the child died during confine- ment, and hence the baby was given into the care of a nursery. The diet consisted of 1 teaspoonful of condensed milk with 12 teaspoonfuls of water and a small pinch of sugar. This was fed every two hours for a period of over two months; later the child was put on barley-water, to which some condensed milk was added. This was changed from time to time to a diet of oatmeal-water and condensed milk. The child had always been frail, and had had a cough and also had an attack of acute capillary bronchitis; during the summer the child had a severe attack of cholera infantum, and almost lost its life from vomiting and purging. For one month this child sub- sisted on a diet of oatmeal-water, rice-water, farina-water, and albumin-water, besides cold tea. Thus it is seen that the child re- ceived no milk for a period of over seven weeks. When the child was five months old it weighed 7 pounds, and at this time it hardly weighs 10 pounds. There is a marked rachitic kyphosis; the ribs are beaded; there is a pendulous belly; the child has an umbilical hernia; the temperature, taken in the rectum at 2 p.m. for a period of at least two weeks, was no higher than 100° to 101° F.; there is an intense thirst; the kidneys are very active; the urine has a very high color; no hematuria could be found. The diagnosis of infantile scurvy was made and the child was put on the following treatment: Orange-juice; lemonade; freshly- expressed steak- juice; raw milk, diluted with barley-water or rice- water, equal parts (4 ounces of milk, 4 ounces of barley-water), repeated every three or four hours, depending upon the appetite. Massage of the body was very gently performed with codliver-oil or vaselin, to lubricate and to nourish. A 1-drop dose of nux vomica was ordered before each feeding. This treatment was given continually for three or four weeks. Every fourth or fifth day a half-ounce of barley-water or rice-water was withdrawn, and instead an equal quantity of fresh milk was added; hence, after four weeks of treatment this child received 6 ounces of milk with 2 ounces of barley-water or rice-water every four hours. The child was sent to the seashore, and after this treatment was continued for seven months all symptoms of scurvy had dis- appeared, though the symptoms of rickets were still very promi- nent. The prognosis now is very good, and the child will un- doubtedly recover. When children have walked, and suddenly stop walk- ing and will not creep, then attention should be directed 298 INFANT-FEEDTNG. to the state of the gums and to the general physical con- dition. Such cases are usually suspicious, and show the beginning of the development of scurvy. Indeed, such symptoms will develop long before there is a general breaking-down. Emaciation and anorexia follow, which are associated in this condition. CHAPTER XLVI. Dentition (Teething). The teeth usually appear, according to Professor Baginsky, between the third and tenth months, though, as a rule, between the ninth and tenth months. The usual rule is for normal dentition to begin about the sev- enth or the eighth month. In a great variety of children premature teething is recorded; I have seen a great many children born with two and more teeth. Rachitic children, as a rule, teeth very early or very late. In the large children's service with which I have been connected I have observed the eruption of teeth many times as early as two or three months in very rickety, bottle-fed children. These teeth soon decay, and are then known as carious teeth. In syphilitic (congenital) children premature denti- tion is frequently seen. The first teeth are known as milk-teeth. The following table will show the usual rule followed by normal dentition in the average child: — 19 | 11 | 13 | 5 | 3 | 4 | 6 | 14 | 9 | 17 20 | 12 | 15 | 7 | T | 2 | 8 | 16~|~T0~ |~18 The milk-teeth are twenty in number; thus, 1 and 2 are the lower incisors, usually first teeth; then follow 3 and 4, upper incisors. Normal children usually teeth in pairs, and not singly, whereas rachitic children usually have an eruption of (299) 300 INFANT-FEEDING. single teeth, and distinct backwardness in their appear- ance. Deciduous teeth, commonly called milk-teeth, re- main until a child is six years old, when the permanent teeth appear. Baginsky emphasizes the fact that enough stress is not laid on the clinical importance of carious teeth as indi- cating tuberculosis and scrofulous conditions. In the sec- tion on treatment of rickets I have mentioned the value of a nitrogenous diet, especially proteids (albuminoids), to aid in the formation of bony structures. The teeth are also included in this category. Fig. 48. — Two Middle Lower Incisors. Three to 10 Months; Average, 7 Months." Thus, when such drugs as glycerophosphate of lime or iron and hygienic measures are indicated for the treat- ment of rickets they are of especial value where back- wardness in teething exists. 77 1 am indebted to Dr. Dillon Brown for the illustrations, which have recently appeared in "The Nursery." DENTITION. 301 Fig. 49. — Nine to 16 Months. Four Upper Incisors. Fig. 50. — Two Lateral Lower Incisors and 4 Anterior Molars. Thirteen to 17 Months. 302 INFANT-FEEDING. Fig. 51. — Four Canines. Sixteen to 21 Months. Fig. 52. — Twenty-three to 36 Months, although the Average is 24 to 30 Months. CHAPTEK XLYII. Athrepsia Infantum. (Marasmus, ok Atrophy; Wast- ing Disease, from Malassimilation of Food.) 78 If infants, when a few months old, suffer with vomit- ing or diarrhoea, and this condition is allowed to become chronic, then colic and flatulence, associated with con- stipation, supervene, and result in a gastro-intestinal ca- tarrh. Neglect of this condition means the development of the condition known as athrepsia. The infant does not thrive, commences to waste, and, unless we realize the condition and give the baby proper treatment, such a child will die of exhaustion from inanition. When these cases linger for months, they develop rachitis. Recovery without treatment is impossible. Parrott was the first to define this disease, and classified it into three stages: — 1. The infant suffers from a simple diarrhoea or loose- ness of the bowels. The stools, instead of being bright yellow and homogeneous, are liquid, curdy, often of a green color, and contain an excessive quantity of mucus. The abdomen is distended with gas and remains con- stantly in this condition; the tongue is coated and the patches of a stomatitis appear in the mouth. The infant is restless, constantly whining, and will not sleep at night. The milk, being retained, curdles; the tissues become flabby, and wasting commences. 2. The symptoms are intensified and the character- istic wasting becomes manifest. The stools, for the most part, are loose and frequent, and consist of undigested food; they are often pale and putty-like, with a pecul- 78 Presented to the Section on Diseases of Children, at the Fifty-first Annual Meeting of the American Medical Association, held at Atlantic City, N. J., June 5-8, 1900. (303) 304 INFANT-FEEDING. iar odor. At other times they are dark brown, from the presence of altered bile. The infant is most voracious, liquid food does not seem to satisfy it, and by the mis- taken kindness of its friends it is fed with some thick food, like soft bread, a diet which has the great advantage, in their eyes, of keeping it quiet for a longer time than liquid food or diluted milk. At times it can hardly be made to sleep, or only dozes for a short time, unless under the influence of a soothing-syrup applied by its nurse. The mouth becomes the seat of a parasitic stomatitis; the skin is harsh and dry; small boils or a lichenous rash make their appearance. The buttocks and genitals are raw and excoriated. The temperature is below normal; the feet and hands are congested; the face has a pallid, earthy tint; and a sickly lactic-acid smell is given out from the body, especially the abdomen. The wasting is extreme, the face being shriveled, the skin wrinkled and hanging in folds about the thighs and arms. 3. The third stage brings the child into a moribund state. It is too feeble to cry, becomes heavy and drowsy, taking little notice of anything. Death then ensues, prob- ably preceded by a muscular twitching, strabismus, or gen- eral convulsions. Henoch does not like the term "athrepsia," intro- duced by Parrott, but prefers "atrophy." The first symp- tom that this author noticed is that the. child's weight does not increase; and hence he emphasizes the impor- tance of frequently weighing children. He regards the weight taken once a week as sufficient, so that it can be a determining factor as to the progress made by an infant. Henoch says that at the end of the first month the weight is increased one-third, at the end of the fifth month it is double, and at the end of the twelfth month it should be three times the weight at birth. Weaning, dentition, and all other pathological conditions interfere with a proper increase in weight. By far the greatest number of cases of athrepsia are ATI1REPSIA INFANTUM. 305 found in bottle-fed children. There are, however, a great many cases to be seen among breast-fed children. We can then be positive that the breast-milk is lacking in some of its chemical constituents, and frequently we find that it is the proteids that are deficient in quantity. If, therefore, we meet with a case of athrepsia in a breast-fed child, the thing to do is to have a chemical examination made of the breast-milk. If the latter is found deficient in quality, then we must withdraw it. A great many children will be found to thrive at once after having been removed from the breasts and changed to some artificial mode of feeding, whereas the reverse is also true. If, therefore, we wish to do away with its own mother's milk, for some positive reason, it is advisable to secure a wet-nurse having a child as near as possible the age of the one she is to suckle. The hereditary history of a nurse is of great importance, as is also the quantity and quality of her milk, which should be thoroughly ex- amined before she is given this foster-child. The treatment of this disease is one which resolves itself into removing the cause, and if bad hygienic sur- roundings — as impure air, crowded apartments, and im- proper diet — are the cause, then these must be remedied at once. Medication amounts to nothing in the treatment of this disease. With hand-fed or bottle-fed children we can easily regulate the condition of their bowels, and also easily regulate the quality and quantity of the food given them. The blandest and least irritating food must be selected, while frequent weighing of the infants should be resorted to in order to ascertain the progress that is being made. Where there is much diarrhoea, milk must be used sparingly or altogether omitted for awhile, as the hard curds formed in the stomach are beyond the weak di- gestive powers of the weakened stomach and intestines. Small quantities of whey and barley-water, white of egg 306 INFANT-FEEDING. and barley-water, or the juice of a rare chop or steak may be given at short intervals during the day and night. As soon as the child improves in respect to the diar- rhoea, milk in some form may be allowed. Peptonized milk is often of much value in these diseases when made by mixing 3 ounces of cold milk, adding 2 teaspoonfuls of cream, with 1 / 2 of a peptonizing powder, and given to the infant after it has stood for fifteen minutes. The cream-mixtures are often of much service, such as 1 ounce of cream, 3 ounces of barley-water, and 1 tea- spoonful of sugar. Every care must be taken that the feeding-bottle is clean, and that the food is prepared with the most scrupulous neatness. The great difference between cows' milk and human milk is the fact that human milk is persistently alkaline, whereas cows' milk is usually acid; that there is more nitrogenous material in cows' milk; that there is a much smaller percentage of milk-sugar in cows' milk, and, finally, that the nitrogenous constituents of the milk of the cow are affected by rennet in a manner different from those of mothers' milk. In order, therefore, to feed cows' milk to infants, these differences must be corrected, and the correction of them causes further differences, which have, in turn, also to be corrected; the process, therefore, is a compli- cated one. Before considering the means adopted to alter the chemical composition of cows' milk, it would be proper to state that there is a common, but false, belief that milk from one cow is the best for infants' use. The principle that underlies this belief is perfectly right. It is, that it is desirable to obtain milk of uniform compo- sition; but it has been found experimentally that milk of the same cow varies in its composition during twenty- four hours, and that it is, in reality, more likely that a mixture of the milk from several cows will show a more constant analytical result than that from one single ani- ATHREPSIA INFANTUM. 307 mal. Jacobi and others have stated that the chances of infection from tuberculosis through the medium of milk can only be lessened by feeding from a large number of cows. In order to render the character of cows' milk similar to that of human milk, it is necessary to reduce the amount of casein in cows' milk. This is usually done by treating the milk with water, thus diluting it; but sometimes lime- water is used, for the reason to be stated immediately. Second, the proportion of fat in cows' milk is less than in human milk, and it has been still further reduced by dilution. Therefore, it is necessary to add to it fat in some form or other, and this is commonly done by adding cream. Thirdly, sugar must be added to cows' milk in order to bring the lactose up to the proper level. It has been held by some that it is necessary to use milk-sugar for this purpose, but there seems to be little doubt that cane- sugar will serve the purpose quite as well, or even better. In the fourth place, according to Jacobi, it is neces- sary to prevent as far as possible the great coagulating effect that the ferment of the infants' gastric juice has on the casein of cows' milk, and this is satisfactorily ac- complished by adding an alkali, such as lime-water, or some mucilaginous material, such as barley-water. In this way the casein curd is rendered loose and flocculent and more like that of human milk. Dr. Meigs, of Philadelphia, advises the preparation of the following mixture: Cream, 2 ounces; milk 1 ounce; lime-water, 2 ounces; sugar- water, 3 ounces; the latter is made by dissolving about 2 1 / 4 ounces of milk- sugar in a pint of water. Condensed cows' milk is simply cows' milk that has been evaporated to one-fourth of its volume and sterilized, nothing at all being added to it. Then, again, there is a form in which the milk is not only condensed, but has also the addition made to it of about 50 per cent, of cane- 308 INFANT-FEEDING. sugar. When it is also borne in mind that the composi- tion of condensed milk varies with the season of the year, great fluctuations must occur in its chemical constitution. Condensed milk must also be diluted with water be- fore it is fit for use, and this dilution may entirely dis- arrange the proportion of the component parts of the fluid. For this reason it is found that even where infants appear to thrive on condensed milk, their apparent good health is due to an excessive deposit of fat, and not to a sufficient supply of albuminoids; and they are, in the long run, more prone to disease than babies fed on the breast or on cows' milk properly prepared. The above remarks apply with less force to that va- riety of condensed milk which is made from sterilized fluid and then sweetened; but even this preparation re- quires for digestibility to be diluted some ten times, and this reduces its nutritive value to a dangerous degree. At times we must resort to various methods of feed- ing, until we find the method on which a baby will thrive, and so it is that we have: (1) humanized milk, (2) steril- ized milk, (3) pasteurized milk, and (4) peptonized milk. 1. Humanized milk is simply cows' milk diluted with a certain amount of whey and with some cream. It is prepared in the following way: A pint of milk is set aside in a cool place until the cream rises to the surface. This is skimmed off and kept, and to the milk remaining is added enough rennet to curdle it thoroughly. The whey is strained off from the curd and added with the cream, previously separated, to a pint of fresh cows' milk, and the mixture is known as humanized milk. It is dis- tinctly more digestible than ordinary diluted milk, and often agrees well with young infants, being given with- out any further dilution, in quantities suitable to the age of the infant. It may be employed exclusively during the first three months of the infant's life, and after that age may be used in combination with some farinaceous food. ATHREPSIA INFANTUM. 309 2. Sterilized milk is that in which all germs tending to decompose it have been destroyed by exposure to a boiling heat at a temperature of 212° F. for a short period of time: from 15 to 45 minutes. Fresh cows' milk always contains impurities received from the cow or the atmosphere or from the vessels in which it is con- tained, though much care may have been taken to main- tain absolute cleanliness. The milk is usually exposed to the action of steam or in a boiling heat from 15 to 45 minutes, and will keep about 24 hours. A fresh bottle must always be opened for each meal; if anything is left in the bottle after the baby has finished, it must be thrown out. 3. Pasteurized milk is simply steamed at a tempera- ture of 140° to 170° F., for about 30 minutes; in other Avords, it is really sterilized milk at a lower temperature. 4. Peptonized milk, the fourth substitute for ordi- nary diluted milk, is as simple a preparation as sterilized milk. It consists of milk which has previously been par- tially digested by the addition of some preparation of a digestive ferment, among the best known of which are Benger's liquor pancreaticus, Fairchild's peptonizing pow- ders, etc. The milk should be diluted to some extent before being peptonized; but it is not necessary to dilute to such an extent as has been recommended for ordinary cows' milk. Generally, even for an infant two or three days old, the addition of an even quantity of barley-water will be sufficient, and, when a baby is two or three months old, a dilution of 2 parts of milk with 1 part of water will be digested with comfort. In France there is a law forbidding anyone to give solid food of any kind to infants under a year without the written authority of a qualified medical man. Jacobi says: "Whatever I have here brought forward is certainly not to disparage the boiling of the milk; it is to prove the danger of relying on a single preventive when the causes of intestinal disorders are so many." It 310 INFANT-FEEDING. is true, however, that the large majority of the latter de- pends on causes which may be met by sterilization, but not by sterilization only; also by pasteurization, that is, heating the milk to 70° C. (165° F.), and keeping it at that uniform temperature for 30 minutes: a procedure which destroys the same germs that are killed by a more elevated temperature, without much change in flavor and taste. One of the questions connected with the employment of sterilized or pasteurized milk is this: whether the milk to be used for a child ought to be prepared at home, or whether the supply may be procured from an establish- ment where large quantities of milk believed to become immutable by sterilization for an indefinite period are kept for sale. In regard to this problem Fliigge plainly ex- presses his regrets that "we have allowed ourselves to be guided by people who are neither hygienists nor physi- cians, but chemists, farmers, or apothecaries, and whose actions have been based on three false beliefs. Of these the first is that boiling for three-quarters of an hour de- stroys germs; the second that whatever bacteria remain undestroyed are innocuous, and the third, that proliferat- ing bacteria can always be recognized by symptoms of decomposition." Nothing is more erroneous. Soxhlet himself, the German originator of sterilization, knew at an early time that the fermenting process is now and then but partially interrupted by boiling, that butyric acid may be found in place of lactic acid, that a strong evolution of gas may be caused after much boiling, and that such milk may give rise to flatulency. Aye, milk which hap- pens to contain the resistant spores of bacteria becomes a better breeding-ground for them by the very elimina- tion of lactic acid, and the longer such sterilized milk is preserved and offered for sale, the worse is its condition. It may be true that these conditions are not met with very frequently, but an occasional single death in a family caused by poisonous milk will be more than enough. ATHREPSIA INFANTUM. 311 Therefore, the daily home-sterilization is by far preferable to the risky purchase from wholesale manufacturers who cannot guarantee, because, in the nature of things, they cannot know, the condition of their wares. Another alteration of a less dangerous character, but far from being desirable, is the separation of cream from sterilized milk which is preserved for sale. Renk 79 found it to take place to a slight extent during the very first weeks, but later to such a degree that 43.5 per cent, of all the cream contained in the milk was eliminated. Sterilization has been claimed to be no unmixed boon, because of its changing the chemical constitution of milk. Still, the opinions on that subject vary to a great extent, the occurrence of changes being both asserted and denied by apparently competent judges. But what I have said a hundred times is still true and borne out by facts, viz. : that no matter how beneficial boiling, or sterilization, or pasteurization may be, they cannot transform cows' milk into woman's milk, and that it is a mistake to believe that the former, by mere sterilization, is a full substitute for the latter. It is true that when we cannot have woman's milk we cannot do without cows' milk. There is no alleged substitute that can be had with equal facility or in sufficient quantity. But after all it is not woman's milk. Babies may not succumb from using it, and may seldom appear to suffer from it; indeed, they will mostly appear to thrive on it, but it is a make-shift after all, and requires modifications. Hammarsten was the first to prove the chemical difference between the casein of cows' milk and of woman's milk. Whatever was known on that sub- ject at that time I collated in Gerhardt's "Handbuch der Kinderk.," vol. i, 1875 (second edition, 1882). But lately Wroblewski demonstrated the difference in solubility of the two milks. Woman's casein retains, during pepsin di- gestion, its nuclein — proteid rich in phosphorus — in solu- 1 Archiv fur Hygiene, xvii. 312 INFANT-FEEDING. tion, wliicli is fully digested; in cows' casein the nuclein is not fully digested, — a "paranuclein" is deposited un- dissolved and undigested. Henry A. Bunker, in an article on the modification of cows' milk, says that the difficulty of the digestion of the casein of cows' milk in some children has seemed to be the resistance to the infant's digestive powers, even after the partial hydration supposed to be brought about by hydrochloric acid and heat. In all such cases the faecal evacuations were white, hard, and dry, such as occur so often on a plain, sterilize.d-milk diet. In many of these cases, these dry, scybalous masses would frequently set up mucous diarrhoea and give rise to severe colicky pains. The only evidence of partial hydration by the acid and heat would seem to be the fact of increased nutri- tion in spite of these difficulties. Professor Chittenden 80 maintains, and proves by a beautiful laboratory experi- ment, that the products of gastric digestion have the power of combining with more hydrochloric acid than the orig- inal proteid, for, as soon as proteolysis commences, the products so formed begin to show their greater affinity for acid by withdrawing acid from its combination with the native proteid : a supposition which is necessary to account for even the starting of the proteolytic process. Further, it is evident that proteoses and peptones combine with a far larger equivalent of acid than the native proteid- albumin, in the experiment. This, doubtless, depends upon the cleavage of the large proteid molecule into a number of smaller or simpler molecules, each of the latter, perhaps, combining with a like number of hydrochloric- acid molecules. However this may be, it is evident that the products of pepsin-proteolysis combine with a larger amount of hydrochloric acid than the mother-proteid, and that the transformation of the latter, at least under the conditions of the experiment, is a slow and gradual process. "Cartwright Lectures on Digestive Proteolysis," 1894. ATHREPSIA INFANTUM. 313 It will be remembered that the original method pro- posed the hydration of the milk-proteids by hydrochloric acid and a rather prolonged boiling. Twenty drops of a 10-per-cent. hydrochloric-acid solution were added to 1 pint of water and 1 quart of milk, and this mixture was to be kept at boiling temperature for about twenty min- utes. The addition of a larger amount of the acid, unless the milk was quite fresh, was found to result quite fre- quently in curdling the milk. It was also found that the acid so added, up to the point of saturation or breaking, exists as combined acid, as was evident from the failure of reagents to show free hydrochloric acid in the completed mixture. The indications that the hydration secured by this method is not always sufficient to meet the requirements of certain infantile stomachs, and the fact that usually in such cases the nutrition is increased in spite of incomplete and painful digestion, seemed so strongly confirmatory of the results of Professor Chittenden's researches, that I determined to copy, in part, his experiments on HC1 saturation, as applied to the proteids of milk. To this end, milk was prepared in the original way, except that the 20 drops of dilute hydrochloric acid were added in 1 / 2 , instead of 1, pint, watery solution, and slowly, but intimately, mixed with 1 quart of milk. This mixture was brought as rapidly as possible to the boiling temperature and then set aside until another half-pint of water was prepared with 20 drops more of the acid. This was added to the previously boiled milk and acid, stirred thoroughly, and again brought to the boiling-point. The result thus obtained was a thoroughly palatable milk, with no taste of having been boiled, and gave no indication of free hydrochloric acid with Gunzberg's reagent. Ru- disch's plan is similar to the latter. Proteids in excess are indicated by the presence of curds in the stools. This is the most frequent cause of colic in infants. Sometimes there is diarrhoea, more often 314 INFANT-FEEDING. constipation when "the proteids are in excess. The excess of proteids frequently causes vomiting and so does an excess of either fat or sugar. If, therefore, after reducing the percentage of proteids, fat, or sugar, vomiting still persists, then we must feed the baby with smaller quan- tities. Thus, we may have to give a 4-ounce bottle where a 6-ounce or a 5-ounce feeding causes vomiting. Certain rules can be laid down: if an infant does not thrive, — that is, does not gain in weight without showing any signs of indigestion, — then the proportions — i.e., percentages of all ingredients — should be gradually increased; chiefly the proteids, however, for the latter is the most important element in an infant's food. An infant soon after birth was put on modified milk, containing : — Fat 2.00 Milk-sugar 5.00 Albuminoids 0.75 Lime-water Via I ordered eight feedings, 2 ounces in each. As the child was constipated, we soon after increased the formula to the following percentages: — Fat 2.50 Milk-sugar 6.00 Albuminoids 1.00 Lime-water Vie As the stools did not change, the fat was increased to 3 per cent., other ingredients the same. The child gained but 3 ounces in weight in five weeks; had green- ish, curded stools, and had distinct evidence of intestinal indigestion. It also vomited curds. The general condi- tion of the child was one of extreme irritability, with very little sleep. Hand-feeding was stopped. The child's ali- mentary tract was thoroughly cleaned, and a wet-nurse secured. This happened when the baby was six weeks ATHREPSIA INFANTUM. 315 old; the child nursed well, gained 6 ounces the first week, 8 ounces the second, and weighed 14 pounds when it was four and a half months old. The child improved until it was seven months old, when suddenly the weight remained stationary. A specimen of breast-milk was sent to John S. Adriance, the chemist of the Nursery and Child's Hos- pital, who found the following percentages: — Fat 2.000 Sugar 7.431 Proteids 0.882 Ash 0.162 Specific gravity, 1031; reaction, alkaline. It is very evident that the deficiency in albuminoids or proteids was accountable for the stationary weight. The child did not gain an ounce in one month. We discharged the wet-nurse, and resorted to hand-feeding, when the child's general condition changed, and she is bright and well to-day. In another instance, a child had been nursed by its own mother for three months, and had gained in weight regularly at the rate of 6 and 7 ounces per week; the stools were normal in quantity and quality, when sud- denly the child appeared to be colicky, was restless at night, had green stools, and did not appear to thrive. For two consecutive weeks the child did not gain in weight, and a specimen of breast-milk was sent to the Pediatrics Laboratory. Mr. E. W. Bailey, the chemist, examined the specimen, with the following result: — Fat 2.43 Proteids 1.25 Sugar 6.51 Ash 0.20 Total solids 10.39 Specific gravity, 1027; reaction, slightly alkaline. 316 INFANT-FEEDING. The percentage of fat and proteids is so low that it was very plain to me why this child did not increase in weight. On putting the child on an oatmeal and top- milk mixture, the digestion improved, the child's sleep was better, and the weight increased. Another case was that of a nursling, brought to me with a history of excessive crying, greenish stools, cheesy curd in the stools, vomiting, restlessness, and a general condition of malassimilation; I asked for a specimen of breast-milk, which Mr. Bailey kindly examined, with the following result : — ■ Fat 4.32 Sugar 6.22 Proteids 1.80 Ash 0.19 Total solids 12.53 Reaction, neutral. The general history of the case showed that the child was fed every time it cried, and thus it was evident that overfeeding was the real cause of the trouble in this case, for I learned that the child frequently nursed for hours at the breast, and was also allowed to go to sleep with the nipple in its mouth. Whenever the child cried it was fed, frequently as often as every half-hour, so that in this case, while the quality of the breast-milk was absolutely nor- mal, as demonstrated by the chemical examination, it re- quired only the judicious interval for feeding to give the child's stomach proper time for the assimilation of its food. CHAPTER XLYIII. Infant-feeding in Summer Complaint. The successful management of a case of summer com- plaint affecting the stomach and bowels depends largely on the feeding. We know that when food is given which is improper in quality or quantity, — in other words, when dietetic errors have been committed, — then the child will suffer with gastro-intestinal or gastric disorders. The nursing baby, fed exclusively from the breast, is usually exempt from summer complaint, unless it is fed irregu- larly or if the milk is of an improper quality. Thus we know that, when breast-milk contains large quantities of colostrum-corpuscles, such milk has a decided laxative effect. What has already been said in regard to the proper supervision of breast-milk, in the chapters on "Breast- feeding" and "Wet-nursing," must be emphasized when it is desired to feed an infant during the summer months. The depressing effect of extreme heat in midsummer naturally tends to lower the vitality of the infant. We must not, therefore, be surprised to find that an appetite, which has been unusually good heretofore, suddenly di- minishes. When the infant shows loss of appetite, noth- ing will tone up the stomach and bowels more quickly than a sudden change of air from the city to the sea- shore. If, in spite of the change of air to the sea-shore, the infant still continues to vomit or to have loose, green- ish, or "muddy" stools (the latter are usually found in that most frequent form of summer complaint known as "colitis"), then the breast-feeding should be stopped and the stomach given complete rest for twenty-four or forty- eight hours. Substitute food such as barley-water, rice- water, albumin-water, or weakened mixed tea to which (317) 318 INFANT-FEEDING. the white of a raw egg has been added; Uiese can be given in teaspoonful doses. Steak-juice can also be advanta- geously given at regular intervals of every three to four hours. In this manner we remove milk from our dietary, for the time being, and give the above liquid nourish- ment, which is easily absorbed. It is a good plan to dextrinize all the cereals, if the child shows a tendency toward vomiting after the milk has been withdrawn. When severe vomiting persists, in spite of the withdrawal of milk and the substitution of the cereals and the white of egg above mentioned, then absolute rest of the stomach must be insisted upon and rectal feeding substituted there- for. RACAHOUT POWDER. 1 pound of rice-powder. 2 ounces of arrowroot. 1 ounce of powdered salep. 2 ounces of sugar of milk. 1 pound of cocoa. 1 vanilla-bean. 1 pound of confectioners' xxx sugar. Mix and thoroughly rub together, put into glass jars, and fasten. Boil 1 teaspoonful with 4 ounces of water. Feed every three or four hours. RECTAL ALIMENTATION. Always cleanse the rectum by using an enema of soap-water or glycerin and water, in the proportion of 4 ounces of glycerin to a pint of warm water, at a tempera- ture of 100° F. Following this rectal cleansing, pepto- nized milk "thoroughly peptonized," or yolk of an egg with starch-water, or beef-blood and starch-water, should be slowly injected. More than 2 ounces should not be used for one feeding enema. This method of feeding has already been described in the chapter on the "Feeding of Diphtheria-Intubation Cases." DIETETIC MANAGEMENT OF A BOTTLE-FED BABY. Discontinue all kinds of food which were given at the beginning of the summer complaint. For example, if INFANT-FEEDING IN SUMMER COMPLAINT. 319 milk has been given, it must be discontinued, and in its place a food which is more easily assimilated must be supplied. Such foods are barley-water, rice-water, farina- water, sago-water or arrowroot-water. These are very easily made by adding a tablespoonful of either one of the above-mentioned cereals to a pint of water and boil- ing the same for about one-half hour; strain through a cheese-cloth, and then add enough water to make 1 pint. This proportion will keep as a stock solution for one or two days, if put into a refrigerator. In hot weather pre- pare daily. In feeding we use 3 to 6 ounces, to which a pinch of salt and some sugar have been added, and warm the same to body-heat immediately before feeding. In making rice- water a much longer time is required to boil the same. For further particulars we refer to the dietary. The quantity to be fed depends on the age of the child; thus, if the child has received 6 ounces of milk at one feeding, prior to its attack of summer complaint, then a good plan is to substitute 6 ounces of barley-water, rice-water, or sago-water for the 6 ounces of milk. It is also a good plan to allow a larger feeding interval during an attack of summer complaint, and to give the stomach and bowels less work. Hence my plan has been to feed every four hours, if the interval prior to the attack has been every three hours. Thirst requires careful management. If the child is very thirsty it is a good plan to give plain boiled water, or to add the white of a raw egg ("albumin-water"). If the child is over one year old, a few drops of expressed meat-juice, made by broiling a steak over a fire and ex- pressing the juice in a lemon-squeezer or meat-press, is advantageous. When the infant's condition is normal and its digestive power is strengthened, then we can grad- ually return to Nature's remedy, namely: milk-feeding. Every physician knows how difficult it is to keep milk fresh and pure during the hot weather, and, therefore, 320 INFANT-FEEDING. in summer it is advisable to pasteurize or sterilize the milk for about fifteen minutes, as soon as it is received from the dairy, and then to keep it in the refrigerator until it is time for feeding. Thus we prevent not only the formation of the germs, but also the development of toxins, which are so death-dealing in midsummer. The most vital point to be considered in the man- agement of summer complaint, next to the diet, is fresh air, and hence, unless children can be given the benefit of daily excursions to the sea-shore or to the mountains, and can be removed from unsanitary and improper hygienic surroundings, we must not look for permanent results. NURSING INFANT. If a nursing infant has summer complaint, then it is advisable to stop nursing. Frequently giving the stom- ach absolute rest for one-half or one whole day will work wonders. The breast-milk should be drawn with the aid of a breast-pump at regular intervals, as though the baby were nursing, and the milk should be thrown away. The same rule applies to the nursing baby as applies to the bottle- fed baby. Thus milk must be temporarily withdrawn and other feeding substituted. DIETABY. Almond-milk. Take 2 ounces of sweet almonds, scald them with boiling water; after a few moments express them from the hulls; then pour the hot water away. Put the blanched almonds into a mortar and pound them thor- oughly, and add either 2 ounces of milk or 2 ounces of plain water. After this is thoroughly mixed, it is to be strained through cheese-cloth, and the strained liquid will, be the almond-milk. Keller's Malt-soup. Take of wheat-flour 50.0 (about 2 ounces). To this add 11 ounces of milk. Soak the wheat-Hour thoroughly, and rub it through a sieve or strainer. Put into a second dish 20 ounces of water, to which add 3 ounces of malt-extract; dissolve the above at a tem- perature of about 120° F., and then add 10 cubic centi- metres (about 2 1 / 2 drachms) of 11-per-cent. potassium bicarbonate solution. Finally mix all of the above ingre- dients, and boil. This gives a food containing: — Albuminoids 2.0 per cent. Fat 1.2 per cent. Carbohydrates 12.1 per cent. There are in this mixture: — Vegetable proteids 0.9 per cent. The wheat-flour is necessary, as otherwise the malt- soup would have a diarrhceal tendency. The alkali is 21 (321) 322 INFANT-FEEDING. added to neutralize the large amount of acid generated in sick children. Biedert emphasizes the importance of giving fat, rather than reducing its quantity, in poorly nourished children, and cites the assimilability of his cream-mixture or of breast-milk in under-fed children as proof of his assertions. The author has used this malt- soup most successfully in the treatment of athrepsia (marasmus) cases in which the children were simply starved. Junket of Milk and Egg. Beat 1 egg to a froth and sweeten with 2 teaspoonfuls of white sugar. Add this to 1 / 2 pint of warm milk; then add 1 teaspoonf ul of essence of pepsin (Tairchild) ; let it stand till it is curdled. The above is useful in typhoid and similar wasting diseases. Plain Junket. — This is sometimes called "curds and whey." Take 1 / 2 pint of fresh, raw milk, and heat it lukewarm. Then add a teaspoonful of Fairchild's essence of pepsin, and stir the mixture thoroughly. Pour into custard cups, and let it stand until firmly curdled. The flavor can be improved by adding some essence of lemon or cinnamon or grated nutmeg. When the essence of pepsin (Fairchild's) cannot be had, or for convenience in traveling, the author has used Hansen's junket tablets, which will give similar results as the liquid essence of pepsin. Peetogenic Milk-powdek. The pancreas ferment trypsin is known to have a remarkable affinity toward milk, digesting its casein with great rapidity without altering its other elements, and without rendering the milk repulsive. When milk is so treated it is known as peptonized milk. Through the ex- pert investigation of the well-known chemist Dr. Albert Leeds, the peptogenic milk-powder was found to yield a milk which was similar to a humanized milk. The author DIETARY. 323 has had some experience in the modification of cows' milk by the addition of peptogenic milk-powder, and can safely say that it is one of the most valuable additions to our infant-feeding that we possess. There are three steps necessary for the preparation of "humanized milk" in using the peptogenic milk- powder : — 1. To prepare — with peptogenic powder, cows' milk, water, and cream — a mixture which has the quantitative composition of average human normal milk. 2. To subject this mixture to the action of the di- gestive principle by which the albuminoids (casein, etc.) are converted into such form as to become identical with those of human milk. 3. To then destroy, the digestive ferment by simply raising the temperature of the milk to the boiling-point. This heat also destroys the bacteria, and renders the milk practically sterile during the time required for its use: twenty-four hours. DIRECTIONS FOR "HUMANIZED MILK." No. 1. — For the daily food of a healthy infant: Put into a clean graniteware or porcelain-lined saucepan one measure (which accompanies each bottle) of peptogenic powder; add to this 1 / 2 pint of cold water, 1 / 2 pint of cold, fresh milk, and 4 tablespoonfuls of cream. Place the saucepan on a hot range or gas-stove, and heat, with constant stirring, until the mixture boils. The heat should be so applied as to make the milk boil in ten minutes. Keep in a clean, well-corked bottle, in a cool place. When needed, shake the bottle, and pour out the desired por- tion, and warm the same before feeding. No. 2. — Specially designed for children with feeble digestion, or when the stomach and bowels are disordered, as in catarrhal conditions. Put into a clean bottle 1 meas- ure of the peptogenic powder, 1 / 2 pint of cold water, 1 / 2 pint of cold, fresh milk, and 4 tablespoonfuls of cream. 324 INFANT-FEEDING. Shake well, place the bottle in a pail or tin kettle of water, holding a gallon, as hot as can be borne by the hand (115° F.), and keep the bottle there for thirty minutes. Then pour all into a saucepan, and quickly heat to boiling- point, with constant stirring. The bottles of the pepto- genic milk-powder made by Fairchild Brothers & Foster have a metal screw-cap, which is the measure above al- luded to. If the infant's digestive powers are still weaker, or if, after feeding the last-named formula, vomiting takes place, then it is safer to use: — One measure of peptogenie milk-powder. One-third pint of raw milk. Two-thirds pint of water. Mix, heat, and boil, as described above, and it is ad- visable to feed at longer intervals; for example, every three or four hours, if the infant has previously been fed every two or three hours. Never use the balance left over in a feeding-bottle after the infant has sucked, but al- ways give a fresh quantity of food for each meal, and whatever the baby leaves should be invariably thrown away. The weight and the stools are important factors in judging when to increase the quantity of milk and cream, or vice versa. Pkedigested Food. To Prepare Rice. — Take 1 / 4 pound of rice, add water, and boil until soft. Break grains by passing through a colander. Take, of bana-diastase (American Ferment Company), 8 grains, and dissolve in 1 ounce of water and add to the rice, which must be kept warm, but not hot. Let stand for two hours at a temperature of 105° F. When rice is thoroughly softened, season with salt, sparingly. Add a little cream if desired. Serve hot or cold. To Prepare Beans or Peas. — Take 1 / 4 pound of beans or peas, add water, and boil until soft. Remove DIETARY. 325 skins by passing through a colander. Take of caroid powder, 4 grains, and of bana-diastase, 8 grains; dissolve in 1 ounce of water. Add to the beans, which must be kept warm, but not hot. Let stand for one hour at a temperature of 105° F. Season slightly with salt. Beans and peas require the double action of proteolytic and starch-converting ferments, as they are composed largely of proteids, as well as starch. Peptonized Milk. Into a clean, quart bottle put the powder contained in one of the Fairchild peptonizing tubes, and a teacupful (gill) of cold water; shake, then add a pint of fresh, cold milk, and shake the mixture again. Place the bottle in water as hot as the whole hand can be held in it with- out discomfort. (About 115° F.) Keep the bottle there five or ten minutes as directed. At the end of that time put the bottle on ice at once to check further digestion and keep the milk from spoil- ing. Place the bottle directly in contact with the ice. The degree of digestion is very simply regulated by the length of time in which the milk is kept warm. partially peptonized milk. Put into a clean agateware or porcelain-lined sauce- pan the powder contained in one of the Fairchild pep- tonizing tubes, and a teacupful (gill) of cold water; stir well ; then add a pint of cold, fresh milk. Heat with con- stant stirring until the mixture boils. The heat should be so applied that the milk will come to a boil in ten min- utes. When cool, strain into a clean bottle, cork well, and keep in a cold place. When needed, shake the bottle, pour out the required portion, and serve cold or hot, as directed by the physician in charge. Milk so prepared will not become bitter. 326 INFANT-FEEDING. IMMEDIATE PROCESS. Put 2 tablespoonfuls (1 ounce) of cold water in a goblet or glass ; dissolve in this one-fourth of the contents of a peptonizing tube; add 8 tablespoonfuls (4 ounces) of warm milk; drink immediately, sipping slowly. If half a pint of milk is required, double the propor- tions of water, peptonizing powder, and milk. COLD PROCESS. Into a clean, quart bottle put the powder contained in 1 of the Fairchild peptonizing tubes, and a teacupful (gill) of cold water; shake, then add a pint of fresh, cold milk ; shake the mixture again and immediately place the bottle on ice, without subjecting it to the water-bath or any heat. Place the bottle directly in contact with the ice. When needed, shake the bottle, pour out the required portion, and use in the same manner as ordinary milk. Peptonized Milk-gruel. Thick, well-boiled, hot gruel 1 / 2 pint. Milk, fresh, cold 1 / 2 pint. Mix and strain into a small pitcher or jar, and im- mediately add the contents of 1 Fairchild peptonizing tube; mix well. Let it stand in the hot water-bath, or warm place, for five minutes, then put in a clean bottle and place on ice. Serve hot or cold. Gruel made from arrowroot, flour, barley, oatmeal, etc., will serve for the purpose. In each instance the farinaceous material should be boiled with water until the starch-granules have been thoroughly swollen, broken up, and incorporated with the water. Whey. To make whey take 1 / 2 pint of fresh milk, heated lukewarm, not warmer than can be agreeably borne by DIETAKT. 327 the mouth (about 115° F.); add 1 teaspoonful of Fair- child's essence of pepsin, and stir just enough to mix. Pour into custard-cups; let it stand until firmly curdled; then beat up with a fork until the curd is finely divided; now strain, and the whey is ready for use. Whey prepared from fresh cows' milk should be alka- line and contain From 0.8 to 1 per cent, of lactaltmmin. 0.03 per cent, of casein. 1.0 per cent, of fat. When such whey is added to milk for an infant under 6 weeks take, of whey, 2 parts; milk, 1 part. This can be increased until equal parts of milk and whey are used for a child several months old. Preparation of Sweet Whey. — Sweet whey is best made by the following method: For each pint of whey needed take 1 pint of whole fresh milk or fat-free milk, heated to 37.7° C. (100° F.), and add 8 cubic centime- tres (2 drachms) of the essence of pepsin or some of the preparations of liquid rennet. This will precipitate the casein in the form of a curd, which is then broken up with a fork; the fluid which remains is the whey. This is strained through two thicknesses of boiled cheese-cloth and one thickness of absorbent cotton and slowly cooled to a temperature of 10° C. (50° F.), and kept on ice until needed. If the whey is to be mixed with cream, it must first be heated to 65.5° C. (150° F.), in order to kill the rennet enzyme. Whey mixtures should not be heated above 68.3° C. (155° F.) if one wishes to keep safely under the coagulation-point of the lactalbumin. Junket (Curds and Whey). Junket. — Take 1 / 2 pint of fresh milk, heated luke- warm — not warmer than can be agreeably borne by the mouth (about 115° F.); add 1 teaspoonful of Fairchild's 328 INFANT-FEEDING. essence of pepsin, and stir just enough to mix. Pour into custard-cups; let it stand until firmly curdled; may be served plain or with sugar and grated nutmeg. An egg beaten to a froth and sweetened with 2 tea- spoonfuls of sugar may previously be added to the half- pint of milk, forming a highly nutritious and smooth jelly. The essence will curdle milk with egg as readily as plain milk. Whey. — Curdle warm milk with the essence of pepsin as above directed; then beat up with a fork until the curd is finely divided; now strain, and the whey is ready for use. Whey is a highly nutritious fluid food peculiarly use- ful in many ailments and always valuable as a means of variety in diet for the sick. It is frequently resorted to as a food for infants to tide over periods of indigestion, summer complaints, etc. Gum- Arabic Water. Dissolve 1 ounce of gum arabic in a pint of boiling water; add 2 tablespoonfuls of sugar, a wineglassful of sherry, and the juice of a large lemon. Cool and add ice. Lime-water. Pour 2 quarts of water over fresh unslaked lime the size of a walnut; stir until slaked, and let stand until clear; then bottle. Lime-water is often ordered with milk to neutralize acidity of the stomach. Tamarind-water. A very refreshing drink may be made by adding 1 pint of hot water to 1 tablespoonful of preserved tama- rinds, and setting aside to cool. Lemonade. Squeeze the juice from 1 lemon. Add 2 tablespoon- fuls of sugar and 1 cup of water. Strain and serve. DIETARY. 329 Milk and Albumin. Put into a clean quart bottle 1 pint of milk, the whites of 2 eggs, and a small pinch of salt. Cork and shake hard for five minutes. Milk-punch. Take 1 / 2 pint of fresh, cold milk and add 2 teaspoon- fuls of sugar, and stir well until dissolved; then add 1 ounce of either brandy or sherry wine. Orangeade. Substitute orange-juice for that of lemon in the recipe for "Lemonade." Tea. Scald out the teapot and put in the tea, using 1 tea- spoonful for 1 cupful. Pour on lolling water, and let teapot stand four or five minutes. If allowed to stand too long, the tannin in the tea is developed, which not only darkens the tea, but also renders it hurtful. Albumin-water. Stir the whites of 2 eggs into 1 / 2 pint of ice-water, without beating; add enough salt or sugar to make it palatable. Apple-water. Slice into a pitcher 1 / 2 dozen juicy sour apples; add 1 tablespoonful of sugar, and pour over them 1 quart of boiling water. Cover closely until cold; then strain. Toast-water. Equal measures of stale bread, toasted, and boiling water. Cut the bread in thin slices, put into pan, and dry thoroughly in a slow oven until crisp and brown. Break in pieces, add water, and let stand one hour. Strain and season. Serve hot or cold. 330 infant-feeding. Barley-water. ■Wash 2 ounces (wineglassful) of pearl barley with cold water. Boil it five minutes in fresh water; throw both waters away; pour on 2 quarts boiling water; boil down to 1 quart. Flavor with thinly cut lemon-rind; add sugar to taste. Do not strain unless at patient's request. How to Prepare Cocoa and Chocolate, cocoa. For each large cup take a teaspoonful of cocoa and a teaspoonful of sugar; mix to a paste with a little boil- ing water or milk; add balance of milk or milk and water, as richness is desired. Let it boil a minute, as boiling improves it. CHOCOLATE (UNSWEETENED). For each breakfastcup take 1 division, break in small pieces, and allow to melt; add milk or milk and water, as richness is desired. Stir constantly. Bring to a boiling- point and set aside to simmer. Sugar to taste. CHOCOLATE (SWEETENED). Take 1 section of a half-pound cake for each cup. Break in pieces in dish and allow to melt without burn- ing. Place the dish over a slow fire; add the necessary quantity of water and milk. A few minutes' boiling will suffice. Stir frequently. Allow to simmer a few minutes. "When milk is contra-indicated, boil the cocoa or choco- late with water only. Coffee (French). Some persons prefer filtered to boiled coffee. Filtered coffee is best made in a French biggin, consisting of two tin vessels, one fitting into the other, the upper one being supplied with strainers. The coffee, being very finely DIETARY. 331 ground, is placed in this utensil, and the boiling water allowed to slowly percolate through it. The pot should be set where it will keep hot, but not boil, until the water has gone through. Pouring it through the coffee a second time will make it stronger, but it loses in flavor. Cafe noir is always made in this way. Nutritious Coffee. Dissolve a little isinglass or gelatin (Knox) in water; put 1 / 2 ounce of freshly ground coffee into a saucepan with 1 pint of new milk, which should be nearly boiling before the coffee is added; boil both together for three minutes; clear it by pouring some of it into a cup and dashing it back again; add the isinglass, and leave the coffee on the back part of the range for a few minutes to settle. Beat up 1 egg in a breakfastcup, and upon it pour the coffee; if preferred, drink without the egg. Eggnog. Scald some milk by putting it, contained in a jug, into a saucepan of boiling water, but do not allow the milk to boil. When cold, beat up a fresh egg with a fork in a tumbler with some sugar; beat to a froth, add a dessertspoonful of brandy, and fill up tumbler with the scalded milk. Soft Custard. Take of cornstarch 2 tablespoonfuls to 1 quart of milk; mix the cornstarch with a small quantity of the milk, and flavor; beat up 2 eggs. Heat the remainder of the milk to near boiling; then add the mixed corn, the eggs, 4 tablespoonfuls of sugar, a little butter, and salt. Boil the custard two minutes, stirring briskly. Calf's-Foot Jelly. Thoroughly clean 2 feet of a calf, cut into pieces, and stew in 2 quarts of water until reduced to 1 quart; when 332 INFANT-FEEDING. cold, take off the fat and separate the jelly from trie sedi- ment. Then put the jelly into a saucepan, with white wine and brandy and flavoring to taste, with the shells and whites of 4 eggs well mixed together; boil for a quarter of an hour, cover it, and let it stand for a short time, and strain while hot through a flannel bag into a mold. Tapioca-cream. Take 1 pint of milk, 2 tablespoonfuls of tapioca, 2 tablespoonfuls of sugar, 1 saltspoonful of salt, and 2 eggs. Wash the tapioca. Add enough water to cover it, and let it stand in a warm place until the tapioca has absorbed the water. Then add the milk and cook in a double boiler, stirring often until the tapioca is clear and transparent. Beat the yolks of the eggs. Add the sugar and salt and the hot milk. Cook until it thickens. Remove from the fire. Add the whites of the eggs, beaten stiff. When cold, add 1 teaspoonful of vanilla. Toasted Bread (Toast, Dry). Cut thin slices of bread into strips, toast carefully and evenly without breaking, slightly butter, and serve immediately on a hot plate. Cream-toast. Take 1 cupful of cream, 1 saltspoonful of salt, 2 slices of dry toast ; or make the same as milk-toast, using cream in place of the milk. If preferred, the slices of toast may be first dipped in hot, salted water. Egg-toast. Take 1 egg, 1 saltspoonful of salt, 1 cupful of milk, 6 slices of bread. Beat the egg lightly ; add the salt and milk. Soak slices of bread in this until soft. Butter a hot griddle; put on the bread; when one side is brown, DIETARY. 333 put a bit of butter on each slice, then turn and brown the other side. Serve with sugar and cinnamon. Milk-toast. Take 1 cupful of milk, 1 / 2 tablespoonful of corn- starch, V 2 tablespoonful of butter, 2 slices of dry toast, 1 saltspoonful of salt. Scald the milk. Melt the butter in a saucepan; when hot and bubbling, add the cornstarch. Pour in the hot milk slowly, beating all the time until smooth. Let it boil up once. Then add the salt. Toast 2 slices of bread. Pour the thickened milk over the slices. Let it stand five minutes. Serve. Baked Apples. Core and pare 2 tart apples; fill the core-holes with sugar; grate over the apples a little nutmeg; add a little water to baking-pan and put in oven and bake until the apples are soft. Serve with rich milk or cream. Sprinkle with icing sugar, if not sweet enough. Mutton-soup. Cut up fine 2 pounds of lean mutton, without fat or skin. Add 1 tablespoonful of barley, . 1 quart of cold water, and a teaspoonful of salt. Let it boil slowly for two hours. If rice is used in place of barley, soak the rice in water over night, if it is to be boiled in the morning. "White Celery Soup. Take 1 / 2 pint of strong beef -tea; add an equal quan- tity of boiled milk, slightly and evenly thickened with flour. Flavor with celery-seeds or pieces of celery, which are to be strained out before serving. Salt to taste. Scrambled Eggs. Take 4 eggs, 1 / 2 teaspoonful of salt, 1 saltspoonful of pepper, V 4 cup of milk, and 1 tablespoonful of butter. 334 INFANT-FEEDING. Beat the eggs lightly; add the salt, pepper, and milk. Put the butter into a saucepan; when melted and hot, add the eggs. Stir over hot water until of a soft, creamy consistency. Serve on buttered toast. Soft-Boiled Eggs. Drop 2 eggs into enough boiling water to cover them. Let them stand on the back of stove, where the water will keep hot, but not boil, for eight minutes. An egg to be properly cooked should never be boiled in boiling water, as the white hardens unevenly before the yolk is cooked. The yolk and white should be of a jelly-like consistency. To Pkedigest Eggs. Break a fresh egg; after thoroughly stirring add to it 2 grains of caroid powder and stir thoroughly. The yolk is at once changed into a limpid liquid and soon, though not so quickly, the albumin is completely dis- solved. This is done at a temperature of from 70° to 80° F. Raw eggs so treated and slightly salted are not un- pleasant to the taste. They may be added to a soup, poured upon dry toast, or mixed with prepared rice. Pkedigested Egg-toast. Upon 2 pieces of toast pour 2 eggs previously digested with caroid as above directed. Now place in oven and allow to remain about three minutes. When ready to be eaten, hot milk may be poured on the toast. The milk cannot be mixed with the egg, or allowed to stand upon the toast for any length of time, because the unspent strength of the caroid present acting upon the casein of the milk will make the entire dish bitter. If eaten imme- diately, the milk will be partially peptonized, but it will not be bitter. DIETARY. 335 Infant's Food. About 1 teaspoonful of gelatin should be dissolved by boiling in 1 / 2 pint of water. Toward the end of the boiling 1 gill of cows' milk and 1 teaspoonful of arrow- root (made into a paste with cold water) are to be stirred into the solution, and 1 to 2 tablespoonfuls of cream added just at the termination of the cooking. It is then to be moderately sweetened with white sugar, when it is ready for use. The whole preparation should occupy about fifteen minutes. Custard Pudding. Break 1 egg into a teacup, and mix thoroughly with sugar to taste; then add milk to nearly fill the cup, mix again, and tie over the cup a small piece of linen; place the cup in a shallow saucepan half-full of water and boil for ten minutes. If it is desired to make a light batter pudding, a tea- spoonful of flour should be mixed in with the milk before tying up the cup. Corn-flour Pudding. Take 1 pint of milk, and mix with it 2 tablespoonfuls of flour; flavor to taste; then boil the whole eight min- utes; allow it to cool in a mold, and serve up with or without jam. Rice Pudding. Take 1 teacupf ul of rice ; wash, and pour over it boil- ing water, and let stand five minutes; then drain off the water and add a cupful of sugar to the rice, a little nut- meg, 2 quarts of milk, and 1 egg. Bake slowly about two hours, stirring occasionally until the last half-hour, then brown. Sago Pudding. Same as above recipe, sago being substituted for rice. 336 infant-feeding. Snow Pudding. Dissolve 1 / 2 box of gelatin in 1 pint of cold water; when soft, add 1 pint of boiling water, the grated rind and juice of 2 lemons, and 2 1 / 2 cupfuls of sugar. Let the gelatinized water stand until cold and beginning to stiffen. Then beat in the well-beaten whites of 5 eggs. Pour into a mold and set on ice. Serve with custard sauce: 1 quart of rich milk, the yolks of 5 eggs, and 2 extra eggs added, and 1 / 2 cupful of sugar. Flavor with vanilla. Peptonized Oysteks. Mince 6 large or 12 small oysters; add to them, in their own liquor, 5 grains of extract of pancreas with 15 grains of sodium bicarbonate (or 1 Fairchild peptonizing tube). This mixture is then brought to blood-heat (98° P.), and maintained, with occasional stirring, at that temperature thirty minutes, when 1 pint of milk is added and the temperature kept up from ten to twenty minutes. Finally, the mass is brought to the boiling-point, strained, and served. Gelatin may be added, and the mixture served cold as a jelly. Cooked tomato, onion, celery, or other flavoring suited to individual taste may be added at beginning of the artificial digestion. Oystek-stew. Take 1 pint of oysters, 1 pint of milk, 1 teaspoonful of salt, x / 4 cupful of water, 1 tablespoonful of butter, and 1 saltspoonful of pepper. Scald the milk. Wash the oysters by adding the water, and remove all shells. Drain, saving the liquor. Put the liquor into a stewpan and heat slowly. Skim carefully. When clear, add the oysters and cook slowly until the edges curl and they are plump. Add the hot milk, butter, salt, and pepper, and serve. Do not let the oysters boil, as that toughens them and renders them indigestible. DIETARY. 337 Oyster-broth. Cut into small pieces 1 pint of small oysters; put them into 1 / 2 pint of cold water, and let them simmer gently for ten minutes over a slow fire. Skim, strain, and add salt and pepper. Arrowroot Pudding. Add the yolks of 2 eggs to the plain arrowroot recipe (following), with 1 teaspoonful of powdered white sugar; mix well and bake in a lightly buttered dish for ten or fifteen minutes. Arrowroot. Mix 1 teaspoonful of Bermuda arrowroot with 4 teaspoonfuls of cold milk. Stir it slowly into 1 / 2 pint of boiling milk, and let it simmer for five minutes. It must be stirred all the time, to prevent lumps and to keep it from burning. Add 1 / 2 teaspoonful of sugar and a pinch of salt, and, if desired, 1 of cinnamon. In place of the cinnamon 1 / 2 teaspoonful of brandy may be used or a dozen large raisins may be boiled in the milk. If the raisins are preferred, they should be stoned and the sugar may be omitted. Oatmeal-gruel. Pound 1 / 2 cup of coarse oatmeal until it is mealy. Put it in a tumbler, and fill the tumbler with cold water. Stir well; let it settle; then pour off the mealy water into a saucepan. Fill again and pour off the water, and again repeat this, being careful each time not to disturb the sediment in the bottom of the tumbler. Boil the water twenty minutes. Season with salt. Thin with a little cream or milk. Strain and serve hot. Chicken-broth. Skin and chop up a small chicken or half a large fowl; put, bones and all, — with a blade of mace, a sprig of 338 INFANT-FEEDING. parsley, 1 tablespoonful of rice, and a crust of bread, — in a quart of water and boil for an hour, skimming it from time to time. Strain through a coarse colander. Clam-broth. "Wash thoroughly 6 large clams in the shell ; put them into a kettle with 1 cupful of water; bring to boil, and keep it boiling one minute; the shells open, the water takes up the proper quantity of juice, and the broth is ready to pour off and serve hot. Add a teaspoonful of finely-pulverized cracker-crumbs, a little butter, and salt to taste. Rice-water. One ounce of well-washed Carolina rice. Macerate for three hours at a gentle heat in a quart of water, and then boil slowly for an hour and strain. It may be sweet- ened and flavored with a little lemon-peel. Useful in diarrhoea, etc., when the flavoring is best dispensed with, and a little old cognac added. Barley-water. Take a tablespoonful of pearl barley, grind it in a coffee-grinder, or pound it in an ordinary mortar; add 1 pint of cold water, and allow it to simmer slowly for about an hour. Strain and add enough water to make 1 pint. Oatmeal-water. Take a tablespoonful of ordinary oatmeal, and add 1 pint of water. Allow it to simmer slowly for one hour and strain. Add enough water to make 1 pint. The same directions apply to making a household mixture of farina- water, rice-water, and sago-water, using the same propor- tions as above. DIETARY. 339 Arrowroot- water. Add 2 tablespoonfuls of arrowroot to 1 pint of water; allow it to simmer for half an hour, stirring it constantly. Egg- water. This is made by mixing thoroughly the white of 1 egg with 6 ounces of water and adding a little salt. The addition of a few grains of sugar will make the child take it better, and adds also a food-element. Such a mixture is one of the best foods we have for temporarily feeding an infant with digestive disturbances when we wish to stop temporarily all milk-food. Artificial Milk. One ounce of suet cut up very finely, and tied loosely in a muslin bag. Boil slowly for an hour in thin barley- water, with 1 / 4 ounce of isinglass and a little sugar of milk, adding a little water occasionally as it boils away. Pound up 12 sweet almonds, pour the fluid slowly on them, and incorporate well. Strain before using. Milk Thickened. A great deal of nourishment can be given in milk by thickening it with either wheat-flour, rice-flour, isin- glass, or gum arabic. The method of doing so is this: with Wheat-flour. — Rub a large spoonful of flour quite smooth, in a few spoonfuls of cold milk. Then add more milk by degrees till you have 1 / 2 pint. Sweeten and flavor with a little cinnamon, and then boil up the milk, stirring it all the time to prevent its getting lumpy. Bice-flour is done in exactly the same way. To thicken milk with isinglass, boil 1 / 2 ounce of it in a pint of new milk, sweetened and flavored. When boil- ing, strain it off. A little less isinglass will do, unless the milk is desired very thick. 340 INFANT-FEEDING. For thickening with gum arabic the proportions will vary according as the milk is wanted more or less thick. If powdered gum arabic is used, it is done in the same way as flour; but if lumps, drop them into hot milk, until it is of the desired thickness, and then boil. There is much nourishment in this hot, and it is very soothing where either chest or stomach are in an irritable state. Rice-milk. Three tablespoonfuls of rice, 1 quart of milk; wash the rice and put into a saucepan with the milk; simmer until the rice is tender, stirring now and then, and sweeten. Tapioca, semolina, vermicelli, and macaroni may be similarly treated. Humanized Mile. A pint of milk is set aside until the cream rises, and this cream is skimmed off and kept. To the milk remain- ing is added enough rennet to curdle it. The whey is strained off the curd and added, with the previously separated cream, to a pint of fresh cows' milk. This is known as humanized milk. In some infants it will be well borne during the first three months, and to this can be added farinaceous liquid for dilution if required. Pasteurized Milk. This is really partially sterilized milk, and consists of sterilization at a temperature of 140° F. instead of 212° F., this sterilization to be continued for from twenty minutes to half an hour. Pasteurized milk should only be used during the twenty-four hours following this process. A good apparatus for this purpose is the one known commercially and to physicians as Freeman's pas- teurizing apparatus. DIETARY. 341 Peptonized Milk. This is milk in which the proteids are changed to peptones, or, in other words, digested, by the addition and action of pancreatic ferment. This process may be stopped when partially performed, giving a product of which the taste is not objectionable; or it may be carried on to complete peptonization, when the product has a very bitter, disagreeable taste. Method. — To peptonize milk partially, add to 1 pint of fresh cows' milk and 4 ounces of water 5 grains of pancreatic extract and 15 grains of bicarbonate of soda. Allow this to stand at a temperature of 105° to 115° F. for five to twenty minutes, then bring to a boil to kill the ferment, or stand on ice to prevent its further action. If the milk is to be used at once, neither of these latter is necessary. To peptonize the milk completely, allow the process to continue for one to two hours. After this time the addition of acid produces no coagulation. In infant-feeding it is better to peptonize a modified than a whole milk. Peptonized milk is frequently very useful in feeding an infant with feeble digestive powers; but it is unwise to continue its use over too long a period, as then the infant's stomach, being called on to do no work, becomes enfeebled from disuse, and gradually un- able to perform its proper function. Whey. — By coagulating 1 pint of fresh milk by add- ing a teaspoonful of essence of pepsin, and allowing this to stand, a solid curd is formed swimming in a liquid (whey). This has the following composition: Proteids, 0.86 per cent.; fat, 0.32 per cent.; sugar, 4.79 per cent.; salts, 0.65 per cent.; water, 93.38 per cent. This at times makes a very valuable food for infants in cases of gastric or intestinal disorder, where the use of milk must for a time be interdicted. Babies like it, it is very easy of digestion, and does not irritate the stomach. A little wine may be added if desired. 342 infant-feeding. Scraped Beef. This is another valuable and easily digested food. It is prepared by scraping with a dull knife some raw or underdone lean beef. A tablespoonful of this salted is the amount usually given at a feeding. Beef-tea in Haste. Scrape 1 pound of lean beef into fibres on a board. Place the scraped meat in a delicately clean white-lined saucepan and pour 1 / 2 pint of boiling water upon it. Cover closely and set by the side of the fire for ten min- utes; strain into a teacup, place the teacup in a basin of ice-cold water; then remove all fat from the surface, pour into a warm cup, warm this gently with hot water or otherwise, and serve. This can be ready in fifteen min- utes, and double the quantity of meat can be used if necessary. Bread and blotting-paper are ineffectual to remove all the fat. A tomato makes excellent flavoring, and other flavors can be added if desired. For children, however, the simpler aliments are the better. Beef-and-Chicken Broth. One pound of good lean beef and a chicken boned should be pounded together in a mortar, and a little salt added, and the whole placed in a saucepan with nearly 3 pints of cold water. Stir over the fire until it boils, then boil half an hour, strain through a coarse sieve, and serve. Liebig's Extract of Beef . Thickened. A teaspoonful of Liebig's extract may be added to a pint of boiling barley-water, with a little salt, or to this may be again added a teacupful of milk, or, instead of the milk, the whites of 2 eggs beaten up with 2 tablespoon- fuls of milk may be stirred into the Liebig beef-tea and barley-water when cool enough to be taken. Too great heat will coagulate the albumin. DIETARY. 343 Chicken-, Veal-, and Mutton- broths. The fleshy part of the knuckle of veal; a chicken, bones and all chopped up; or 2 pounds of the scrag end of neck of mutton, added to 2 pints of water, with a little pepper and salt, and boiled two hours and strained, all make excellent broths. Pearl barley, rice, or vermicelli, boiled separately till quite soft, may be added when either of the broths is heated for use. All fat must always be carefully removed by skimming when cold. Beef-juice. Expressed beef-juice is obtained by slightly broiling a piece of lean beef, and then squeezing the juice from it by a lemon-squeezer. ■ One pound of steak yields 2 or 3 ounces of juice. This is flavored with salt and given cold or warm. Do not heat enough to coagulate the albumin. This is very nutritious and usually well taken. It may be given at the rate of a tablespoonful three times a day. Good, Nutritious Beee-tea. Mince 1 pound of good beef (from which all skin, fat, etc., has been carefully removed) and pour upon it in an earthen jar 1 pint of cold water. Stir, and let it stand for one hour. Then place the jar in a moderate oven for one hour, or stand the jar in a saucepan of water and allow the water to boil gently for an hour. To be exact, the heat to which the beef-tea is raised should not exceed 180° F. Strain through a coarse sieve and allow it to grow cold. When wanted, remove every particle of fat from the top ; warm up as much as may be required, add- ing a little salt. Beef-tea should, except in the hottest weather, be made a day before it is wanted. Essence of Beef (with Heat). One pound of gravy-beef free from skin and fat, chop as fine as mincemeat, pound in a mortar with 3 table- 344 INFANT-FEEDING. spoonfuls of soft water, and soak for two hours. Then put in a covered earthen jar with a little salt, cement the edges of the cover with pudding paste, and tie a piece of cloth over the top. Place the jar in a pot half-full of boiling water, and keep the pot on the fire for four hours, simmering. Strain off the liquid essence through a coarse sieve; it will be about 5 or 6 ounces in quantity. One teaspoonful frequently, with or without wine or brandy, as may be ordered. A teaspoonful of cream may occa- sionally be added with advantage to 4 ounces of the essence, or it may be thickened with flour, arrowroot, or sago. Essence of Beef (Another Way, Without Heat). Half a pound of fresh beef cut up as finely as pos- sible; to this add 1 / 2 pint of pure, soft, cold water (rain- water is excellent, filtered, if necessary, from the nature of the vessels in which collected, as iron tanks, etc.); an eggspoonful of salt, and 5 drops of pure hydrochloric acid (spirit of salt). Mix and stir well, and after an hour filter through a conical sieve without pressure. The fluid must be returned into the sieve until it runs through clear. Next, another 1 / 2 pint of cold, pure, soft water is to be poured on the meat in the sieve, and this is also to run through without pressure. The result will be about 3 / 4 pint of a red solution of meat containing most of the albumin, coloring and flavoring matters, salts, and other soluble materials. Half a wineglassful of this may be taken cold for a child twelve years old; a teaspoonful to a dessert or tablespoonful for younger children. Or it may be slightly warmed by standing in a jar immersed in hot — not boiling — water. It may be colored with burnt sugar, if desirable. This is a veritable meat-essence, and is of use in extreme prostration, notably after burns, in continued fever, in some cases of dyspepsia, and in the diarrhoea of infants, as alluded to elsewhere. DIETARY. 345 Fkesh Pabula. These contain essentially the so-called antiscorbutic element, and may be given, not only to provide this un- known but necessary constituent of food, but also as additional nutrient agents. The chief articles are: — Raw Meat-juice.- — To prepare this take 2 ounces of gravy-beef, free from fat, and chop into small pieces ; add to 2 ounces (4 tablespoonfuls) of water in a cup, and stand in a warm place for half an hour; then squeeze through muslin to express the juice. The temperature of the meat-juice must never be above lukewarm, or the soluble albuminoids will be coagulated and its value destroyed. Raw meat-juice will not keep for more than 10 or 12 hours, and should be made fresh whenever wanted. Bananas. — Fresh ripe bananas, either grated or sieved, afford a valuable fruit food. It has been found that bananas with milk will constitute a useful nourishing food for infants. Egg-albumin. — Egg-albumin is prepared for use by stirring up the white of 1 new-laid egg with 4 ounces of water. Prepared thus and sweetened, it may take the place, for a time, of the ordinary milk diet in infantile diarrhoea, after appropriate treatment with repeated small doses of calomel. Egg-albumin can hardly be considered as a substitute for raw meat-juice, which contains only about 3 per cent, of albumin (myosin), but which is a powerful digestive stimulant, owing to the presence of extractives (creatin, etc.). LIST OF BOOKS CONSULTED. Baginsky: "Diseases of Children," 1902. Henoch: "Diseases of Children." Biedert : "Infant-feeding." Monti: "Infant-feeding and Dietetics." Jacobi: "Intestinal Diseases of Infancy and Childhood." Jacobi: "Therapeutics of Infancy and Childhood." Article by T. M. Rotch, in Jacobi "Festschrift." Hammersten : "Text-book of Physiological Chemistry." Hammersten : Eichhorst, "Clinical Pathology." Archiv fur Kinderheilkunde (editor, Professor Baginsky). Wing: "Milk and its Products." Ellis: "Diseases of Children." Tuttle Gallaudet: "Diseases of Children." Keating : "Encyclopaedia." H. Neumann, Berlin: "Ernahrungsweise und Infectionskrankheiten im Sauglingsalter." W. Knoepfelmacher, Vienna: "Verdauungsruckstande bei der Emahrung Mit Kuhmilch." Sternberg: "Manual of Bacteriology." Hueppe: "Principles of Bacteriology." Pfeiffer: "Analysis of Milk," Wiesbaden, 1887. Heubner: "Sauglingsernaehrung und Saeuglings-spitaeler," Berlin, 1897. Holt: "Diseases of Children." R. Schroter: "Jahrbuch fur Kinderheilkunde," 1887. A. Wroblewski: "Beitrage zur Kenntnis des Frauencaseins, etc. Mittheilungen aus den Kliniken und medicinischen Instituten der Schweiz," 1894. J. Lehmann: "Milchuntersuchungen," Pfluger's Archiv, 1894. Fr. Soldner: "Die Salze der Milch," etc. Inauguration dissertation, Langensalza, 1888. Th. Escherich:. "Jahrbuch fur Kinderheilkunde," 1891. E. Salkowski and M. Hahn: Pniiger's Archiv, 1895. H. Wegscheider: "Ueber die normale Verdauung bei Sauglingen," Berlin, 1875. O. Heubner: "Berliner klinische Wochenschrift, 1894. J. Uffelmann: Pfliiger's Archiv, 1882. (346) LIST OF BOOKS CONSULTED. 347 Biedert: "Jahrbuch fur Kinderheilkunde," 1881. Th. Escherich: Miinchener niedicinische Wochenschrift, 1889. F. Soxhlet: Miinchener medicinische Wochenschrift, 1893. Th. Escherich: "Verhandlungen der XI Versamnilung der Gesell- schaft fur Kinderheilkunde," 1894. Gartner: Ibidem, 1894. A. Jacobi: in Gerhardt's "Handbuch der Kinderheilkunde." INDEX. Absorption 21 of carbohydrates 14 of fat 10 Achroodextrin 11 Acid, hydrochloric, the addition of, to food 72 lactic, quantity of, in infant's stomach 3 Acidity, relative., of an infant's stomach 2 Acids in the infant's stomach 2 After weaning, time of feeding 84 Albumin and the gastric juice 15 -water 329 Albuminose 29 Albuminous, or proteid, substances \ . . . 29 Almond-milk 321 Amylopsin 11 Apple-water 329 Arrowroot 337 pudding 337 -water 339 Athrepsia infantum 303 causes of 305 feeding in 305 stages of 303 Bacillus acidi lactici 113 "b," summary of 53 'd" of Booker 44 1 of Booker 45 f" of Booker 46 ' of Booker 48 'h" of Booker 49 "k" of Booker 49 ' of Booker 50 Backhaus's milk 221 Bacteria of the intestine 39 Bacterium coli commune 39 biological characters of 41 morphology of 40 pathogenesis of 43 varieties of 44 Bacterium lactis aerogenes 51 biological characters of 52 morphology of 51 pathogenesis of 52 Baked apples 333 Bananas 345 (348) INDEX. 349 PAGE Barley-water 330, 338 Barlow's disease from improper feeding 183 Beef -arid-chicken broth 342 essence of 343, 344 -juice 343 scraped 342 -tea 343 -tea in haste 342 Biedert's cream, directions for making 146 cream-mixtures 146 Bile, cholesterin in 18 glycocholic acid in 18 in nurslings 18 lecithin in 18 mucin in 18 quantity of : 18 unorganized ferments in 18 Bottle-brush 188 -feeding 144 amount of milk to be given in 144 general rules for 151 Breast-feeding 67 rules for 67 suggestions for 68 time for 67 Breast-milk 60 composition of 62 immunity by 56 proteids, method for estimation of 31 -pump 90 specimen of, for chemical examination 64 Brooder 197 Buttermilk feeding 115 how to prepare for infants 115 quality of 118 Calf's-foot jelly 331 Cane-sugar 139 Carbohydrates 26 and their formulae 21 Cellulose 22 Cereal milk 211 composition of, when prepared 211 Chicken-broth 337 veal-, and mutton- broths 343 Chloride of sodium 28 Chocolate 227 sweetened 339 unsweetened 330 Clam-broth 38 Clinical illustrations of how to feed 154 Cocoa 226 and chocolate cocoa, how to prepare 330 Coffee, French 339 350 INDEX. PAGE Coffee, nutrition 331 Coit's decimal method for home-modification of milk 148 Colic 271 causes of 271 drug treatment of 273 massage in 272 sugar as a cause of 274 Colostrum 30, 55 Condensed milk or cream 224 quantity of sugar in 224 Constipation 275 causes of 276 dietetic treatment of 284 drug treatment of 280 electricity in 283 exercise for 284 hygienic treatment of 285 immediate relief of 279 massage in 283 water for 279 Corn-flour pudding 335 Cow, the breed of a 127 Cows, age of 128 tuberculin reaction in Ill Cows' food 110 Cows' milk 107 albuminoids in 129 analysis of 107 average percentage of fat in 110 composition, variation, and production of 107 lime-salts in 33 properties of 97 raw 98 solutions for rendering alkaline 140 yellowish 112 Cream 134 decimal 148 eight-per-cent 135 for home-modification 134 how to procure 135 -mixture, Biedert's 145 ordinary 134 to pasteurize the 136 -toast 332 twelve-per-cent 135 uses of 134 Curds and whey 327 Custard pudding 335 Cyanosis in premature infants 198 Dairy, the ideal 133 Dentition 299 Dextrose 11 alcoholic fermentation of 12 INDEX. 351 PAGE Diastasic action of succus entericus 12 Diastasis . . . 22 Diet after the period of weaning 87 Dietary 321 Dietetic management of a bottle-fed baby 318 Dried-milk foods 206 Drugs taken by a nursing woman, influence of on baby 69 Egg-albumin 345 -toast 332 -water 339 Eggnog 331 Eggs, scrambled 333 soft-boiled 334 to predigest 334 Enzymes 22 Epithelium and the glands, secretory and absorbing power of.. 16 Erythrodextrin 11 Eskay's albumenized food 214 composition of, when prepared 215 Faeces, peptonizing ferment in 266 proteids in 266 quantity of 265 saccharin ferment in 266 Farinaceous dried-milk foods 207 Fat, absorption of 27 diarrhoea 265 -globules in milk 71 Fats 26 and carbohydrates, value of 27 Feeding children afflicted with cleft palate 260 • forced 195, 250 dangers of 196 in diphtheria-intubation cases 254 infants, general rules for 105 mixed 69 nasal 252 in diphtheria 257 modus operandi of 252 quantity of food in 252 of infants in incubators 194 method of 194 results of 199 of sick children 72 rectal, general rules for 258 in diphtheria 254 rules for 152 -table and cream-mixtures 145 -bottles 189 Fermentation 12, 13 lactic 12 of sugar 13 Ferments and their actions 11 352 INDEX. PAGE Ferments, organized 20 unorganized, table of 19 Flour-ball feeding ' 71 Food, addition of hydrochloric acid to 72 Foods, additional, during the nursing period 71 Freeman's pasteurizer 180 Gas in the intestine, function of 15 Gastric juice, influence of, on pathogenic germs 4 of infantile stomach 2 power of transforming albumin 15 Gavage 250 Giaourdi 114 Glandular system of infants, development of 16 Glucose 12 Grape-sugar 11 Gruels, dextrinized 191 method of dextrinizing 191 Gum-arabic water 328 Hand-feeding 144 Home modilier, materna 166 Horlick's malted milk 209 composition of, when prepared 209 Humanized milk 217 composition of, when prepared 217 directions for 323 Hydrocarbons 26 Hydrochloric acid in the infant's stomach 2 Hydrolysis 22 Hydrolytic agents 20 Ice-cream and water-ices 227 Imperial granum 213 composition of, when prepared 213 Incubator treatment of premature infants, results of 199 -feeding 194 Incubators, method of feeding in 194 Infant- feeding 103 in summer complaint 317 Infant-foods 206 as adjuncts to fresh cows' milk 206 Infant-stools 261 Infants, general rules for feeding 105 premature 197 Infants' food 335 saliva 2 weight 92 Intestinal muscles, action of 16 Intestine, infantile, formation of gas in 15 Intestine, length of 15 Junket 327 of milk and egg 322 INDEX. 353 PAGE Keller's malt-soup 231, 321 Koumiss 114 Laboratory modification of milk 236 Lactose 13 Lahmann's vegetable-milk 222 Lemonade 328 Levulose 13 Liebig's extract of beef, thickened 342 Lime-salts in cows' milk 33 -water 328 and milk 34 Liver and bile in nurslings 18 Long rubber tubes 190 Malassimilation of food 303 Malt-diastase, action of 23 -extracts 193 Malted dried-milk foods 207 Maltose 11, 12 Mammary glands, the two 56 Marasmus 303 Meat, raw, beneficial effects of 102 Mellin's food 215 composition of, when prepared 215 formulae and analyses for preparing 216 Men suckling children 58 Microbes in the milk of nursing women 70 Milk, addition of glycerin to 140 sugar to 139 aerated 204 albuminoids of 64 and albumin 329 artificial 339 bacteriology of 125 bicarbonate of soda in 34 burettes 31 certified 204 changes in, by boiling 171 by sterilization 164 curdling and diluents of 129 detection and addition of preservatives to 122 directions for pasteurizing 179 effect of alkalies on 128 of heating 164 fat in 25 formaldehyde as an addition to 122 fresh raw 100 frozen 113 home-modification of 148 human, properties of 96 modification of 136 of men's breasts 59 pasteurization of 172 23 INDEX. PAGE Milk, pasteurized 177, 340 peptonized 341 phosphorus in 64 proteids in 31 raw, assimilation of 100 salicylic acid as an addition to 124 salts contained in 131 Soxhlet's method of sterilizing 174 sour 113 sterilized 173 substitute for, in diseases of stomach and intestines .... 106 sugar in 25 -teeth 299 test for salicylic acid in 124 tests for formaldehyde in 122 thickened 339 witch's 57 woman's, methods of changing the ingredients in 78 idiosyncrasies in children 228 -modifying gauge 168 -punch 329 salty 126 -sugar 35 bacteria in 38 impurities in 37 process of making 35 solutions 138 -toast 333 Milkine 210 Milking, precautions necessary in 127 Milking time and stage of 128 Mother-milk, Professor Gaertner 218 Muscles, intestinal, action of 16 Mutton-soup 333 Nathan Straus milk-laboratories and similar charities 268 Nestle's food 208 Nipple, ventilated 187 -shield 89 -sterilizer 188 Nipples and bottles 185 artificial 185 mode of cleansing 185 management of woman's 89 before the baby is born 89 odor of 188 recommended 187 tender 90 Nursing centre 2 mother, the diet of a 73 Oatmeal-gruel 337 -water 338 Orangeade 329 INDEX. 355 PAGE Oyster-broth 337 -stew 336 Oysters, peptonized 336 Partially peptonized milk 325 Pepsin and hydrochloric acid in infant's stomach 3 Peptogenic milk-powder 217, 322 Peptones 29 Peptonized milk 325 milk -gruel 326 Predigested beans 324 peas 324 eggs 334 egg-toast 334 food 324 how to prepare .* 324 rice 324 Ptyalin 11 Putrefaction 20 Kacahout powder 318 Rachitis 288 causes of 289 diet required in 291 external treatment of 291 internal treatment of 292 prevention of 288 prognosis of 291 Paw meat-juice 345 Pectal alimentation in summer complaint 318 Rice-milk 340 -pudding 335 -water 338 Saccharated skim-milk 149 Sago-pudding 335 Saliva, action of, on various bacteria 4 secretion of 2 Salts 28 and water 29 Schedule for feeding and formulae ; 153 Schizomycetes, intestinal, diastasie action of 12 Scorbutus 294 Scurvy 101, 294 avoidance of 105 value of milk in 105 Scybala, removal of 280 Secretory and absorbent power of the epithelium and glands . . 16 Self-weaning 84 Sick children, the feeding of 72 Siphon, to clean the glass 137 Snow-pudding 336 Soft custard 331 Starch, saccharification of 22 35G INDEX. PAGE Starch, soluble 22 Statistics of births and deaths 286 Sterility of human milk 70 Stomach, acids in the 2 amount of secretion in 2 capacity 6 infantile 1 mucous membrane of the 1 muscular fibres of 1 ptyalin in 11 quantity of lactic acid in 3 relative acidity of 2 Stool, dyspeptic 265 of a nursling 261 Stools 263 blood in - 263 brown 263, 264 casein in 265 jelly-like masses in 264 long shreds of mucus in 265 mucus in 264 muddy 264 reaction of 262 typical green 263 white or light gray 264 Succus entericus, diastasic action of 12 Sucrose 13 Sucking act 2 centre 2 Sugar, contra-indications to the use of 139 in milk 25 solution, standard 149 Summer complaint in a nursing infant 320 Tamarind-water 328 Tapioca-cream 332 Tea 329 Teething 299 Toast, dry 332 -water 329 Toasted bread 332 Top-milk 135 Tuberculous diseases in children, causes of 112 Tyndallization 183 Walker-Gordon laboratory milk 236 Wampole's milk-food 212 composition of when prepared 212 Wasting disease 303 Water in the feeding of infants 142 quantity of, to be given to infants 142 Weaning 76 and feeding from one year to fifteen months 82 INDEX. 357 PAGE Weighing to determine the quantity of milk an infant has taken 93 Weight-chart for an infant 95 Wet-nurse 76 diet of a 77 manner of living 77 Wet-nursing 79 Whey 326, 328 White celery soup 333 Zomotherapy 102 .^=Le^U~\j