COLUMBIA LIBRARIES OFFSITE HEALTH SCIENCES STANDARD HX00014699 P 1,1,,), ■ II., ,,Vli'.>: (Mi.'-'.-l.!. n'.fi'»'.r.! :ilr-.C','''0 Uliiiii •T' ■n'f''', Columbia ®nibersiitp^V^ in tfje Citp of i^eto l^orfe / ^ ^ r COLLEGE OF PHYSICIANS AND SURGEONS Reference Library Given by M' w ■V.?:^:; Digitized by tine Internet Arciiive in 2010 witii funding from Open Knowledge Commons (for the Medical Heritage Library project) http://www.archive.org/details/surgeryitsprinciOOashh SURGERY ITS PRINCIPLES ANT) l^RACTTCE FOR ST[TDENTS AND PRACTITIONERS BY ASTLEY PASTON CoOPER ASHHUIIST. A.B., M.D., F.A.CS INSTRUCTOR IN SURGERY IN THE UNIVERSITY OF PENNSYLVANIA, ASSOCIATE SURGEON TO THE EPISCOPAL HOSPITAL AND ASSISTANT SURGEON TO THE PHILADELPHIA ORTHOP-EDIC HOSPITAL AND INFIRMARY FOR NERVOUS DISEASES WITH 7 COLORED PLATES AND 1032 ILLUSTRATIONS IN THE TEXT MOSTLY ORIGINAL LEA & FEBIGER PHILADELPHIA AND X E \V YORK Entered according to the Act of Congress, in the N-ear 1914, bj^ LEA & FEBIGER, in the Office of the Librarian of Congress. All rights reserved. TO RICHARD H. HARTE A SIRGEOX OF WIDE CLINICAL EXPERIENCE AX ABLE TEACHER A WISE CONSULTANT A SAFE AND SKILFUL OPERATOR THIS VOLUME IS GRATEFULLY DEDICATED BY HIS PUPIL, ASSISTANT AND FRIEND THE AUTHOR I'liKKACK. I'j" is the function of a work such as this to furnish the foundation on which a knowledjje of Surgery is to be built. Didactic and chnical lectures, i)apers in current journals, classical monographs, and par- ticularly the student's clinical work and the surgeon's daily practice are valuable adjuncts, but unless the foundations have been laid broad and deep, no useful superstructure can be erected. A text-book shoukl afford a true perspective, placing the various branches of study in their proper relative position, maintaining their just proportions, and providing a source of information which shall indicate where further knowledge is to be gained. A student seeks clear and accurate statements, and desires to have facts set definitely before him. If the present volume supplies these wants, if it helps the student to learn surgery and proves a useful reference work for the practitioner, it will have fulfilled its purpose. Every text-book, however, has its limitations. At best it can but teach the student to know; it cannot teach him to do. And though knowledge is power, much practical experience in laboratory, dis- pensary and hospital wards must supplement didactic instruction. In the present work emphasis is placed on the underlying principles, and pathogenesis, diagnosis^ and indications for treatment have received particular attention. Descriptions of operations, however, have not been slighted. The more important operations have been described in detail, and in every case an attempt has been made to present clearly, if briefly, at least one method of operative procedure. The specialties of the Eye, the Ear, the Nose, and the Throat naturally are not included; and Genito-urinary Surgery, Gynecology, and Orthopedics have been discussed only so far as they come within the province of the general surgeon. Neither publishers nor author have spared any pains in the endeavor to furnish a text-book on Surgery w^hich shall be acceptable to the profession. The illustrations, with very few exceptions, are entirely original, and are reproductions of photographs or sketches made by the writer in his various services, especially at the Episcopal Hospital of Philadelphia. To his long association with this Hospital he owes unsurpassed opportunities for clinical work; as well as to his associa- tion with the Orthopaedic Hospital, and to his former services at the Pennsylvania, the Children's, and the German Hospitals. Most of the skiagraphs are derived from the Episcopal Hospital, and were made by Dr. Thomas S. Stew^art or his Assistant, Dr. A. U. Wilkinson. vi PREFACE Those from the Orthopiedic Hospital were made by Dr. Wm. \nn Korb. The ilhistrations of operative technique are based largely on work done in the writer's Laboratory of Operative Surgery in the I'niversity of Pennsyhaiiia. The credit for converting the author's diagrams and photographs into admirable illustrations is due to Mr. Charles F. Bauer. Much help has been derived from other text-l)ooks and systems of surgery. First and foremost among these must be mentioned the Principles and Practice of Surgery of John Ashhurst, Jr. The indebted- ness of the writer of the present work to that \olume can be appre- ciated best by those who, like himself, acquired the basis of their surgical education from its pages. Every other source of inff)rmation has been studiously sought; and, thanks to the facilities afforded by the Library of the College of Physicians of Philadelphia, this laborious task has been rendered comparatively easy. It was thought inadvis- able to cumber the text with bibliographical references, but the dates of publication of authoritative contributions, whether recent or of historical interest, have been indicated, and it is believed that by this means the original references may be more easily found in the Index Medicus or in the I^idex Catalogue of the Surgeon- GeneraVs Library, U. S. Army. The author is particularly indebted to the Avritings of Deaver on abdominal and prostatic surgery; and free citations have been made from the \olumes pu])lishcd In- this brilliant surgeon in collaboration with the writer. The text of the present volume has receixcd the criticisms of several of the author's friends. Dr. Henry Winsor and Dr. Penn-Gaskell Skillern, Jr., have devoted themselves to this work most unselfishly, and have offered many valuable corrections and suggestions. Dr. G. G. Davis and Dr. Frank D. Dickson have kindly reviewed the chapters on Orthopedic Surgery and on Diseases of the Joints. Dr. A. D. Whiting has assisted in reading the proof-sheets, and has made the index. A. P. C. A. 811 Spruce Street, Philadelphia, 1914. ( onti:nts. GENERAL SURGERY. ("HAPTKR I. Inflammation' 17 CHAPTER II. Diseases Resulting from Inflammation 47 CHAPTER 111. MoDiFiKU Forms of Inflammation (^8urc;ical Infections) .... 7t) CHAPTER IV. Tl-MOHS 101 CHAPTER V. SuROK.'AL Techniqie 133 CHAPTER VI. ' I.nmuries and their Effects 159 CHAPTER VII. Gunshot Wounds 180 CHAPTER VIII. Amp[t.\tions 192 CH.M'TER IX. Effects of Heat and Cold; Injuries by Electric Currents, Lightning AND the Rontgex Rays; Skin-grafting and Plastic Surgery . . 217 viii CONTENTS SYSTEMIC SURGERY. CHAPTER X. .Surgery of the BLOOD-VASfULAU System 227 CHAPTER XI. Surgery of the Skin, Bur.s.-e, Lymphatics, Muscles, Tendons, and Nerves 259 CHAPTER XII. Fractures 294 CHAPTER XHI. Injuries of Joints . 385 CHAPTER XIV. Diseases of Bone 416 CHAPTER XV. Diseases of Joints 451 CHAPTER XVI. Orthopedic SuRCiERY ^^4 REGIONAL SURGERY. CHAPTER XVII. SUR(iKHY OF THE HeAD ^^1 CHAPTER XVII I. Surgery of the Spine ^^^ CHAPTER XIX. Surgery of the Face, Mouth, and Neck •>19 CHAPTER XX. Surgery of the Breast, Chest Wall, Lungs, and Diaphragm 699 CONTENTS IX ClIAFTKll XXI. Hkrnia 753 C'lIAPTKK XXII. AuDOMINALSuKCIKKY in GeNEHAL, and LnJUKIES OI' the AI3U0.M1NAI> VlSCEHA 802 CHAPTER XXIII. Surgery of the Ga.stro-inte.stinal Tract 848 CHAPTER XXIV. Surgery of the Call-uladder, Liver, Pancre.\s, and Spleen 919 CHAPTER XXV. Surgery of the Bladder and Kidneys 958 CHAPTER XXVI. Venereal Diseases ' . . . 989 CHAPTER XXVII. Surgery' of the Urethra and Prostate 1015 CHAPTER XXVIII. Surgery' of the Male Genital Org.\ns 1043 CHAPTER XXIX. Surgery of the Female Genitals 1064 SLIllGERV; ITS I'liLNCIPI.ES A.XJ) I'llACTICE. The word Surj^ery (old English Chirurgery) is derived from two Greek words, yt'-i' and ^l')'"'", signifying respectively hand and work; as distingnished from the work of the physician, surgery was there- fore formerly confined to such mechanical procedures as were carried out by the surgeon under the direction of the physician. Such was the position of the surgeon in the middle ages; but, since the time of Ambroise Pare (1509-1.190), who is thus justly styled the Father of Modern Surgery, the Science and Art of Surgery have advanced step by step toward such a point of perfection as long since to have entitled them to equal rank with ^Medicine. And though the highest func- tions of surgery still remain mechanical in nature, it is no longer the physician who plans and directs the mechanical treatment, but the surgeon himself who selects the patient, devises the operation, and determines at what stage of the malady surgical measures shall be employed. Underlying all disease, and therefore necessary to an understand- ing of disease processes, surgeons encounter a pathological state which constitutes the process by which the bodily tissues react to injury. If the injury be very severe, immediate death of the part may ensue; and there will then be, in that part, no reaction to the injury. At the \ev\ outset of the study of surgery, it is proper to discuss at some length the reaction which takes place when the tissues are injured, because only when the underlying principles of disease and injury ha\'e been thoroughly mastered, can it be hoped to study with profit the special affections which subsequently will be discussed. chapter i. l\fla:\imation. The process by which the tissues react to an irritant is known as Inflammation. The student must therefore learn what are the usual irritants which produce these changes; he must study the changes themselves, and their results; he must familiarize himself with the subjective and objective symptoms due to these tissue changes; and he must finally learn how to relieve the patient of his suft'ering. It 1 8 IX FLA MM A TION therefore becomes necessary to discuss the causes, the pathology, the symptoms, and the treatment of inflammation. Causes. — The predisposing causes of inflammation are those which render the patient especially liable to the action of irritants, which are the exciting causes. Any constitutional state, therefore, which lowers the resistance to disease or injury will act as a predisposing cause. Age, especially the extremes of life, influences the develop- ment of inflammation in this way. Occupation and habits also have an undoubted influence, by undermining or by strengthening the con- stitution. Past or present diseases may very seriously modify the patient's resistance to the exciting causes of inflammation. In general it may be admitted that the exciting or determining causes of inflammation are either mechanical or chemical, using these terms in their broadest sense, and including in the latter all causes (thermal, electrical, radio-active, infective) which are not distinctly mechanical in their action. But while it is expedient to acknowl- edge that the process of repair which occurs after such mechanical injuries as contusions, fractures, aseptic wounds, and the like is in very fact an inflammatory process, it is nevertheless proper to recog- nize the fact that the vast majority of inflammatory affections are directly due to chemical irritants produced in the tissues by micro- organisms, especially bacteria. Indeed, it is seldom susceptible of satisfactory proof that bacteria are entirely absent in the class of injuries first mentioned; for it is probable that all patients, and even persons in good health (Adami), have somewhere in their system certain bacteria which, being carried by the blood or lymph currents, eventually will reach the region of damaged tissue, and will there be enabled to prosecute their nefarious work to better advantage than where there exists no locus minoris resistentioe . Foreign bodies were cited formerly as examples of purely mechani- cal causes of inflammation; but unless it can be proved that the foreign body is aseptic, and that the part of the body where it lodges (eye, skin) is also free from bacteria, it is proper to assume even in such cases that the resulting inflammatory reaction, if noticeable, is due as much to bacteria as to the presence of a foreign body. Indeed, we know that many sterile foreign bodies (ligatures, sutures) constantly remain in the tissues after aseptic operations, and are productive of no manifest inflammatory reaction. Likewise calculi, formed in the internal organs, if sterile themselves, may be productive of only trivial discomfort until bacterial infection occurs in their containing viscus. The bacteria which surgeons most frequently encounter as causes of inflammation are the Micrococcus pyogenes (Staphylococcus); Streptococcus pyogenes; Bacillus coli commimis; Gonococcus; Bacillus pyocyaneus; Pneumococcus; Bacillus typhosus; Bacillus tuberculosis; Bacillus tetani; Bacillus mallei; Bacillus anthracis; Bacillus oedematis maligni; Bacillus aerogenes capsulatus, etc. These microorganisms are known as Pathogenic Bacteria, because PArilOLOGY 19 they are thcnisolves the causes of (Hsease; tliey take up their abode and thri\e in li\iug tissues, which tliey use as pahuhun. Tliey are to be distinguished from Saprophytic Bacteria, which exist only in dead tissues; these can be rep;arded as causes of disease only in a more or less indirect maimer, because it is necessary that other agents, chiefly the patliogenic bacteria, shall have previously brought about the death of the tissues. In addition to bacteria, certain other forms of microorganismal life must be recognized as occasional causes of the inflammatory process in man. Among these are certain animal parasites, certain Yeasts, or Blastomycetes, and certain ^loulds, or IIyi)homycctes. Among the more important of the latter may be mentioned Oidium Albicans, which causes Thrush; the various forms of fungi, which cause the skin lesions of favus, tinea, etc.; and the Ray Fungus, which causes Actinomycosis. The chemical substances produced by pathogenic bacteria, as a result of their action upon the tissues, are described by the general name toxiris (Roux and Yersin, 1888); endo-toxins are those substances formed in the bodies of dead or dying bacteria. Both toxins and endo-toxins act as chemical irritants, and it is these products of bacteria, and not the bacteria themselves, w^hich are regarded as causes of inflammation. The products of pathogenic bacteria are albnniinoid in nature; those elaborated by saprophytic bacteria are alkaloidal, and go by the general name ptomains. The action of thermal, electrical, and radio-active agents as causes of inflammation will be discussed under separate sections in other portions of this volume. Pathology. — The pathology of the inflammatory process is the same in kind, though varying somewhat in its characteristics, according to the irritant cause, and to the particular tissue aflfected. Certain bacteria produce a reaction so peculiarly characteristic that surgeons have dignified the resulting processes by erecting them into diseases to which special names are applied. Such are Tuberculosis, Syphilis, Anthrax, Glanders, and other affections which are grouped together as the Infectious Granulomas. These diseases therefore are described in a separate chapter (Chapter III); in the present chapter will be described only those changes which are usually understood when the term inflammation is used. Even among the })acteria which cause the changes universally recognized as inflammation, the form of reaction varies considerably, so that it is sometimes possible to assert without microscopical or bacteriological examination that the inflam- mation is due to one variety of bacteria, not to another. It is also sometimes possible for the experienced observer to assert that the same variety of microorganism is the cause of quite divergent types of inflammation in different organs or tissues of the body. If one were to watch under the microscope the changes which occur in a part on which an irritant is acting, he would obtain a very accurate idea of the process of inflammation. This may be done in the patho- logical laboratory; but great experience is required properly to inter- 20 /.VF/..LV.V.4 770.V pret what is seen; and for practical purposes it is better to study, at leisure, a series of illustrations of an inflamed area, made at various stages of the process. Studyintr first the vascular tiss-ues, it is noted that the capillaries dilate, those which before were too small to allow the entrance of the cellular elements of the blood now increase in diameter, and it is even possible that new vascular channels may be formed. More blood comes to the part, more blood passes through it, and more blood leaves it, than in the normal state. This change is spoken of as active hyperemia {determination, fluxion of blood j, to distinguish it from passive hyperemia or congestion; in this latter state, although there is more blood actually in the part than in the normal state, yet the blood ^■%f/^^'"^' M:^ Fig. 1. — Subcutaneous tissue some distance above dead part in a case of spreading gangrene. Note stasi-'i, margination, and inigration. Three veins packed with leuko- cytes (I), which are escaping freely. Around the arterj- (below) there are none. Out- side the vessels many larger cells are seen. X 200. (Green.) is more or less stagnated in the part, and does not leave it. owing to venous obstruction, which is the prime cause of the congestion. In inflammation, although no cause of venous obstruction exists, the active hyperemia above described soon undergoes a change, so that the picture more nearly resembles that seen in congestion. The blood moves more slowly through the vessels, the blood cells, espe- cially the leukocytes, tend to cling to the vessel walls (margination), and eventually some of the leukocytes escape through spaces between the endothelial cells lining the capillaries by a process known as migra- tion (.1. F. Cohnheim. ISfi?). In some cases of severe inflammation the erythrocytes may be forced out of the vessels as well ((liapefh'sis). In the case of the leukocytes, however, the process is active (migration), and is not a mere matter of filtration by the vis a tergo. According p.\Tiioj/)(;y 21 to recent observations it seems prohiihle that the en throcytes escape from the vesssels in tlie wake of the knikocytes, heiiifj:; sncked out by the currents i)ro(hice;reat benefit from \\<\\\^ an antiseptic j)<)ultice composed of gauze soaked in ecjual parts of ('»() i)er cent, alcohol and corrosive sublimate solution (i to 2()(K)), applied dripi)in, which are made in torm> suitable to the various parts arteeted. leaking is partieuhiriy appHcahie to chrouie forms of artliritis witliout efi'usion; wliile the eupi)in^ glass apparatus is said to he of value in tlie treatment of chronic sinuses, ete. ; it has also been used in uterine attections. It is probable that the novelt\' of this treatment is causing it to be indiscriminately employed in many atieetions where it can only do harm. Massage is of value in the later stages of inflammation, by pro- moting absorption of the exudate, rupturing slight inflammatory adhe- sions; and thus aiding the restoration of normal i:)hysiological action. In enforced confinement to bed, massage may be advisable to sustain the tone of the muscles of those parts not directly concerned in the disease. Constitutional Treatment. — ConstituiionaJ rest, as well as local rest of the inflamed })art, is often requisite. Rest in bed, in a quiet, cool, darkened room, may enable the patient to be restored to his activi- ties in a few days, whereas a much longer period frequently would be required were he to persist in going about the house. Especially should such rest be insisted upon in the case of acute inflammations of the chief organs of the body — pyelitis, cystitis, prostatitis, affec- tions of the gall-bladder and other abdominal organs. Hy(/iene is of the utmost importance. The room of the patient, or the hospital ward, should be well ventilated, and easily warmed in winter, and cool in summer. Bathing must not be neglected, for the skin is an important excretory organ. The excretions must be watched daily, and in most cases a careful examination of the urine should be made, both as to quality and quantity. Cathartics should be given as needed; a brisk purge early in the attack is usually bene- ficial. A temperature chart should be kept, and the temperature, pulse, and respiration be recorded twice daily. As the patient will often be unable to entertain himself while laid up, the surgeon should see that such light entertainment as is deemed suitable is provided. The best surgeons are physicians also, and must not let their pro- fessional duty cease with the dressing of the wound or the applica- tion of a splint. On the other hand, I have sometimes seen patients who were exhausted by over-entertainment, all the members of the family congregating in the sick man's room to spend the evening, vitiating the atmosphere, and wearying the patient's mind by constant chattering among themselves. It is usually well to limit the visitors to two at a time; and to caution them to cease their visit and their conversation when the sick man no longer appears interested. The diet in cases of inflammation should be simple; so long as fever continues, liquid diet is preferable. ^Milk, which is the most univer- sally applicable article of food, usually can be taken by any patient, in spite of his prejudices, if he makes the attempt, ajid if the milk is fresh and cold. A few patients prefer it warmed. Its taste may be disguised by the use of vanilla, chocolate, coffee, etc. All kinds of 42 INFLAMMATION broths are suitable; fresh beef jiiiee often is rehshed, or the various prepared forms of meat juice may l)e employed. Liquid peptonoids is an excellent article of diet. When the fever has gone, more liberal diet may be allowed : eggs, oysters, sweetbreads, chicken, chops, green vegetables, ice-cream, etc. As a rule, the patient's own desires and tastes furnish a fairly reliable guide to his diet; and if no injurious effects are manifest, he may be permitted to eat pretty much what he pleases. Drugs are of undoubted value in the treatment of inflammation. Those most employed may be classed as (1) Sedatives; (2) Cathartics; (3) Diuretics and Diaphoretics; (4) Stimulants; (5) Alteratives; (6) Tonics. Sedatives.- — Opium is one of the most valuable single remedies in the pharmacopoeia; but its tendency to produce constipation must be guarded against; and it is too valuable a remedy to be used indis- criminately. I never prescribe it unless there appears to be a definite therapeutic indication for its use; I consider its routine use in opera- tions or other surgical affections as extremely injudicious. If the patient is in pain, it is the surgeon's duty to relieve the pain so far as is compatible with the cure of the disease; but usually pain may be relieved without resort to opium, by change of position, by prompt incision of an abscess, or by rest enforced by splint or bandages. If the pain really demands morphin for its relief, I think it is usually better to administer one-sixth of a grain hypodermically, and to repeat this in an hour if the patient is not relieved. In extensive burns, I order a quarter of a grain for an adult immediately, and have this dose repeated at short intervals until relief is obtained. There is no torture so great as that of a burn so extensive as to ensure death within a few hours; and it is inhuman to withhold the means of euthan- asia from such patients. Closely allied to its power of producing sleep, is the action of opium for injuries of the head, in traumatic delirium, delirium tremens, etc. Besides relieving pain and securing sleep, opium serves to relax spasm; it thus proves of benefit in fractures; in retention of urine from congestion of the posterior urethra, in fissure of the anus, in pylorospasm, and similar aft'ections. If opium is contraindicated, other sedatives may take its place; among the most valuable of these are chloral, the bromides, hyoscin, cannabis indica, and paraldehyde. Trional is a useful hypnotic, but has no influence on pain. Aconite may be given in small doses during the height of the inflammatory fever, when of the sthenic type. Veratrum viride and antimony are now seldom used. The latter was formerly employed in the endeavor to abort inflammation by means of its so-called "anticipatory antiplastic eftect." Calomel, for the same purpose, was strongly commended by the late Prof. Ashhurst, in the treatment of head injuries, and I constantly employ it with utmost satisfaction. Catharatics usually may be administered with benefit in the early stages of inflammation. In this way toxins are withdrawn from the circulating blood, and prevented from reaching the kidneys in excess, CONSTirVTIONAL TREATMENT 43 u here they ;ire prone to ciiuse (•h)U(ly swelhii''' or (les(|ii;iiiiat i\ c neph- ritis. In ])eritonitis 1 heHe\e the use ol' eathiirties to he positively harinfiil. In inenin<;itis it is desirahle to keep the bowels freely oj)en. A single dose of castor oil, or blue i)ill, or divided doses of calomel (gr. g hourly till gr. j has been taken) will be of more benefit in most cases than the popular use of salts. After having the bowels thoroughly o])ened once, it is usually inadvisahle to continue purging the patient. If constii)ation i)ersists, enemas may be used. AsafVx'tida supposi- tories, or milk of asafoetida by enema, are supposed to overcome flatulence. 1 have considerable doubt whether they have any very definite action. Diurciics and diaphoretics were much employed formerly, and they undoubtedly are of benefit in some cases. Plenty of water by mouth is the best diuretic; when this is contraindicated, or if it can- not be taken, resort may be had to rectal, subcutaneous, or intraven- ous injections of saline solution. The kidneys are the chief organs of elimination for the toxins produced at the seat of inflammation, and by the iml)ibition of plenty of fluid the function of the kidneys is promoted, and the toxins are excreted in a more or less diluted form. Dover's powder combines the merits of an hypnotic with those of a diaphoretic. The vegetable salts of potassium and ammonium (citrate and acetate) are especially valuable as diuretics because they are not themselves irritating; moreover, they lessen the viscosity of the blood. Digitalis and strophanthus are more stimulating; these, or the citrate of caff'ein, may be used when the heart shows signs of failure. Stivwiants seldom can be dispensed with in severe cases after the height of the fever has passed. Alcohol, when taken in small quanti- ties, aids the al)sorption of food; it seems to act almost as a food itself when little else can be retained. It should be given in doses large enough to produce the desired effect; the amount naturally will vary with the age and habits of the patient, with his general condition, and with the condition of his heart and kidneys. The initial dose should be small (one-half ounce three or four times daily), and it should be increased rapidly so long as it appears to do good. In men- ingitis it is contraindicated, as tending to increase delirium; but in delirious states due purely to adynamia, as in extensive burns, or other exhausting diseases, the use of tonic doses of alcohol frequently will cause the mental state to clear up promptly. Its use in delirium tremens is to be condemned. If the delirium, from any cause, is increased by the alcohol, it is doing the patient no good, and should be reduced in quantity or discontinued entirely. Whisky and brandy are the })est forms in which to administer alcohol during the inflam- mation; during convalescence, ale, beer, porter, or the lighter wines may be used. Champagne is the only form in which it is usually advisable to administer alcohol during the continuance of high fever. Coffee is a valuable stimulant. It may be administered by mouth or bv enema. The same is true of salt solution, as alreadv noted when 44 INFLAMMATION speakinjj; of diuretics. Atropiu, (li of the leg. Episcopal Hospital. usually is due to some trivial injury, repair of which becomes impossible from the necessity of the patients continuing their occupa- tions as means of livelihood, and because of some constitutional condition (obesity, arteriosclerosis) which interferes with the normal circulation of the blood and lymph in the part. If the patient be put to bed and the callous margins of the ulcer be softened by poultices or simple wet dressings, the ulcer usually will soon be con- verted into one of the healthy type, and cure will soon be brought about. As soon, however, as the patient resumes his occupation, the old ulcer is apt to reappear whenever the skin is bruised. It is important, on this account, to take great pains to avoid injury and to maintain the skin in good condition, when once the ulcer has healed. Scrupulous cleanlinesss should be enjoined; and ofi DISEASES RESULTING FROM IXFLAMMATIOX wliere a tendency to edema of the leg exists, much l)enefit may be gained from the use of an elastic bandage, which usually is preferable to an elastic stocking. But it may be impossible for the patient to be laid up in bed for some weeks, which is the shortest time in which a cure may be anticipated; yet even with- out the advantages of rest in the recumbent position, it is by no means impossible to bring about a cure of the ulcer. Poultices and wet dressings may be applied while the patient continues at his work, and when the margins of the ulcer have become reasonably soft, it may be strapped with adhesive plaster, thus supporting the edges, preventing a re-accumulation of blood and lymph in the parts, and mechanically promoting healing of the base. The straps should be an inch or an inch and a half wide, long enough to encircle about three-fourths of the limb when obliquely applied ; and are to be put on from below upward in an imbri- cated manner, two at a time, thus drawing the edges of the ulcer to- gether as the two straps are crossed (Fig. 13). The strapping, which should start an inch or so below the tilcer, and continue for an equal distance above its upper margin, should be covered in by a firm muslin bandage, extending from the patient's toes to his knee. This dressing may remain in place for from five days to a week; when it is to be removed, the skin should be washed with turpentine, the edges of the ulcer (just within the blue Ime of new skin) touched with the solid stick of silver nitrate, and the straps again applied and covered in with a firm bandage as before. ^Mien the ulcer assumes the character of a simple or healthy ulcer, strapping may be discontinued, and ointments may by applied; but frequently the ulcer will heal under the use of straps alone. The results of this treatment, when it is carefully carried out, are remarkable: ulcers which have been open for a year or more, and on which all manner of salves have been tried, may be completely healed within comparatively few weeks. It is usually best for the patient to continue to keep the leg bandaged for a long time after apparent cure has been obtained, since relapses are frequent. In the rare cases where rest in bed, poultices, and strapping, fail to cure an indolent ulcer, its conversion into a healthy ulcer sometimes may be accelerated by dividing its callous margin by several radiating Fig. 1-3. — Strapping a leg ulcer. Episcopal Hospital. ULCER 57 incisions, or vvvu l)y iiiakiiit;' criss-cross incisions extending' llironfj;h the base of the nicer and its eallons niaruin on l)otli sides. Or the nk'er may he nn(kT-ent I'rom the sides, separatini^; its base c()nii)letely from tlie (k'ep fascia. Skiit gnij'tutg (p. '2'2'A) lias heen employed to hasten the cicatrization of these ulcers, but without much success. Formal plastic operations (p. 225) occasionally have been adopted, but with no very jicrmanent results. A great many of these callous leg ulcers are due to the unsuspected presence of syphilis. Tlie typical syphUiiic leg ulcer (Fig. 14) is situated above the middle of the leg, is characteristically round, is seldom very ])ainfu], and yields with Fig. 14. — Syphilitic ulcer of leg, male, aged twenty-four year.s. Following "ru- pia" of six weeks' duration. Completely healed under anti-syphilitic treatment in three weeks. Episcopal Hospital. Fiu. 15. — Varicose leg ulcer. Episcopal Hospital. remarkable facility to the administration of mercury and the iodides. But in many of the callous ulcers in which no definite history of syphilis can be obtained, much improvement often follows the adminis- tration of potassium iodide alone or with mercury. In almost all cases of leg ulcer of long duration the tibia immediately beneath the seat of disease becomes thickened; but in the case of syphilitic ulcers there is sclerosis of the bones, and as pointed out by Coues the diagnosis of syphilitic leg ulcer usually may be confirmed by a skiagraj)h. In very exceptional cases the callous ulcer is absolutely incurable. But life with an incurable leg ulcer is by no means impos- 58 DISEASES RESULTIXG FROM IXFLAMMATIOX sible; indeed, many persons live for fifteen to twenty years, or longer, with unhealed le*; ulcers, and are able to lead very active lives. It is only in the rarest instances, therefore, that amputation is justi- fiable; for the risk to life usually is much less from an unhealeti leg ulcer than from amputation. Varicose Ulcer. — This is one associated with varicose veins (Fig. 15). It is difficult to heal, sometimes is attended by alarming hemorrhages, and frequently incapacitates the patient. The use of elastic bandages, hot baths, gentle massage, etc., by reducing the swelling, and improv- ing the circulation of the limb, sometimes will bring about a cure, or at least will keep the patient in comfort. If palliative measures fail, excision of the affected veins may be done; but the operation is one of more risk than when no ulcer exists, and sliould not be undertaken lightly. It should never be done in the presence of active phleliitis; and if the veins are thrombosed as the result of a former phlef)itis, they should be divided through healthy portions above the limit of tlie clot. Warty Ulcer. — Under this name Marjolin (1846) described a form of ulcer which of late years usually has been regarded as due to malignant clianges. It is not correct, how- ever, to give the name of Marjolin to every ulcer which undergoes malignant transfor- mation, as his original description applied merely to the clinical appearance of tlie ulcer, as if covered with warts. Fig. 16 represents a typical warty ulcer, whicli healed rapidly under appropriate treatment. When of long standing a malignant ulcer whose surface is warty frequently is found to involve the bone, which is the seat of caries, perhaps due to a primary sarcoma of bone, or possibly involved secondarily by a surface epithelioma. If the warty ulcer is malignant, it is much safer to amputate tlie limb than to attempt excision; but if the malignant ulcer is of the heel (I have seen two cases following burns in this situation), resection may properly be done, with restoration of tlie foot by the method of ^Mikulicz, if the patient refuses amputation. Gangrene (sphacelus, mortification, slough- ing) is a term used to describe the process of death of the soft parts, or of an entire extremity with its contained bone, when this death occurs in mass; necrosis, though usually confined in its application to death of bone, is occasionally employed to describe the death of soft parts at a depth from the surface, where no marked inflammatory phenomena are present, the resulting necrotic masses corresponding very closely to Fig. 16. — Warty ulcer of Marjolin connected with periosteitis eight months after typhoid fever. From direct injury. Aged fourteen years. Episcopal Hospital. GANGRENE 59 the sequestra met with in necrosis of l)()ne. In ulceration, tlie dead parts are cast otV in tlie form of pus (liquefaction necrosis), and moleriihir drafli of the tissues is sai(l to occur; whereas in f^anj^rene (molar dnttli) the i)arts cast o(f (sloughs) are of such size as to he clearly visible to the naked eye. The causes of gangrene are either direct (as in pulpefaction of a limb by crushing force, destruction by caustics, by heat or cold, by bacterial toxins, etc.), or indirect, from interference with the vascular supply. One of the most extensive cases of sloughing I ever saw was in a lad of 16 years, whose whole lower extremity had passed through cog-wheels; though there was no injur}- to the ^'ascu- lar supply of the limb, the pressure of each cog produced immediate death of the area it crushed, and it was over ten weeks be- fore the sloughs had all separated and the resulting ulcers healed. The appearance of the cicatrices six years after the accident is shown in Fig. 17. Injuries which in a normal state of health would cause only trivial lesions, when complicated by vascu- lar o})struction or constitutional disease mav result in verv extensive sloughing Fig. 17. — Cicatrices from sloughing, .six years after in- jury (cog-wheels). Episcopal Hospital. Fig. 18. — Gangrene following application for twenty-four hours by patient's mother of carbolic acid dressing. Episcopal Hospital. or gangrene. The same degree of inflammatory infiltration, which in the subcutaneous tissues would be harmless, when occurring beneath the palmar fascia or other dense fibrous membrane may produce such a choking off of the ])lood-supply as to cause extensive necrosis of the structures involved. In the old, or in younger persons with marked arteriosclerosis, so-called senile gangrene may follow trifling injuries, or may be caused by gradual occlusion of the arteries without external injury. In diabetics there is a special tendency to necrotic processes, among the mildest of which are furuncles with their central slough or core. In patients suffering from ergotism, gangrene of the fingers or toes, perhaps symmetrical, is a not infrequent phenomenon. It is usually preceded by premonitory symptoms, such as formication, cramps, 60 DISEASES RESULTING FROM INFLAMMATION local asphyxia, etc. Certain lesions of the nerwms sysfcin, jirobably through vaso-motor changes, may induce hed-sores, siougliing, etc., in an alarmingly short space of time. The so-called perforating ulcer of the foot (p. 261), probably is due to a similar change, though arteriosclerosis is usually a factor also. Carbolic acid gangrene (Fig. 18) results from the direct caustic action of the solution employed, and often follows the use of a weak solution which becomes concentrated by evaporation. Bacteria are not a necessary accompaniment of gangrene; their presence usually is incidental. In a few rare instances, bacterial toxins are believed to be the immediate cause of gangrene by causing endarteritis, phlebitis, and thrombosis. This is probably the case in noma (p. 63). Emphysematous gangrene (p. 65) is due to infec- tion with gas-producing bacteria, the production of gas preceding the development of gangrene. Saprophytic bacteria usually invade tissues which have already become gangrenous, and produce the malodorous gases characteristic of putrefaction. There are two main varieties of gangrene, the moisi and the dry, dependent in large measure upon the amount of moisture in the part when the vascular current is occluded, and on the amoimt of evaporation which takes place. ]\Ioist gangrene usually is due to venous obstruction (thrombosis, pressure of tumors, splints, bandages, etc.); it is occasionally seen, however, after sudden occlusion of the main artery of a limb (embolism, wounds, ligation, etc.), if the venous blood already present remains in the part. Dry gangrene, of which the senile form is typical, usually is due to slowly progressing arterial occlusion, the parts deprived of vascular supply becoming mummi- fied. Diabetic gangrene is usually rather dry. Symptoms. — When a part which has been inflamed becomes gan- grenous, the color fades into bluish green or purple, and finally into black; the pain, at first burning and intolerable, suddenly ceases; the affected area becomes numb and senseless; the cuticle is raised in bullae filled with bloody or purulent fluid; the part instead of being tense feels doughy; and the local temperature falls. There is gradually formed, at the point where the resistive powers of the individual are sufficient to overcome the destructive lesions producing the gangrene, a line of demarcation, indicated by a red line encircling the gangrenous structures. In this region the usual phenomena of inflammation occur, and as this process continues, a line of granula- tions is formed, known as the line of separation. By the gradual increase of these granulations the dead tissues are pushed away, as it were; and unless assisted by the surgeon this tedious process will continue until the entire gangrenous area is extruded in the form of a slough. An entire limb may be amputated spontaneously in this way. During the formation of the line of demarcation, there is often considerable constitutional disturbance, due to the sapremia caused by absorption from the imperfectly isolated gangrenous area; and TREATMENT OF GANGRENE 61 even during the process of gramilation, before the slough is cast off, the patient is constantly exposed to infection from the decayed struc- tures. These constitutional symi)toms usually are much less or altogether absent in dry gangrene, where the process, as already mentioned, resembles munnnification. Treatment. — The separation of sloughs sometimes seems to be hastened b\- poulticing the part. The charcoal poultice is particularly useful in these cases, as it lessens the odor by absorbing tlie gases. The yeast poultice also acts well. \ arious chemical digestants have been used, in the eti'ort to aid nature in dissolving the sloughs; but little more is thus accomplished than by simply kee{)ing the parts clean and protecting them from outside infection. In the case of extensive gangrene, tlie most important thing is to prevent infection; amputation will surely be required later, but if infection is absent the surgeon can safely postpone it until some indication is present of the le^'el at which it must be done. Early amputation is often needlessly high. In moist gangrene constant irrigation with dilute antiseptics is one of the surest methods of preventing infection; in dry gangrene it usually is sufficient to keep the parts well covered with sterile cotton. Periodical baking of the limb, as in chronic joint affections, is also of great service. In senile gangrene, where only one or two toes are affected, formal amputation may never be required, as nature will be able to remove the slough at one of the phalangeal joints with less constitutional disturbance than w^ould be caused by an operation ; if the gangrene extends beyond the toes, how- ever, amputation should be done above the ankle; and if it extends above the ankle, amputation through the lower third of the tbigli should be done : it is not advisable to wait for the line of demarcation, and to amputate at low^r points than those named almost certainly would expose the patient to recurrence of gangrene in the stump. To determine the level at w^hich amputation should be done Lejars employs (1909) the "comparative hyperemia" test: the limb is elevated, an elastic bandage is applied, exsanguinating it, and exsan- guination is maintained by an Esmarch band for five or ten minutes after the elastic bandage is removed; the hyperemic blush which follows the removal of the Esmarch band will extend only so far as healthy circulation is present, and amputation may be done safely at this point. In the healthy limb the hyperemic blush extends to the toes. Arterio-venous anastomosis (" reversal of the circulation") as a method of treatment for gangrene, is discussed at p. 2-11. In many cases of senile gangrene it is evident that any operation would only hasten the fatal termination; under such circumstances of course only palliative treatment is admissable. In diabetic gangrene (Fig. 19) amputation is not to be recommended until sepsis threatens. De Witt Stetten (1912) has shown .the remarkable success which attends judicious conservative treatment, especially sterilization of the limb by repeated baking. Amputation for gangrene following frost-bite and bums, sht)uld not be done until the line of demarcation has 62 DISEASES RESULTING FROM INFLAMMATION formed, as it is impossible to know heforeliand at what le\'el the limb must be removed. In the case of gangrene resulting from local injury due to crushes, compound fractures, etc., amputation should be done as soon as gangrene is manifest; it is impossible to pre- vent infection in such cases, and delay in resorting to amputation usually will cost the patient his life. When gangrene is due to arterial occlusion (embolism, ligation for wound), amputation should be done at the site of the occlusion, as soon as gangrene is evident (Guthrie, 1815); but in the case of injury to the superficial femoral artery, amputation below the knee usually is sufficient, and occasion- ally in the upper extremity a collateral circulation may be estab- lished. Special Forms of Gangrene. — Decubitus or bed-sore (Fig. 21) is due to necrosis of the skin and subcutaneous tissues from long continued pressure on bony promi- nences in those confined to bed, especially in those with debilitating diseases or in a helpless condition. Favorite sites are over the sacrum and sacro-iliac joints (Fig. Fig. 19. — Diabetic gangrene. Aged seventy-four years. Duration two months. Healed under conservative treatment. Episcopal Hospital. re- 22); but any point ceiving constant pressure (occiput, scapulae, elbows, heels, malleoli) may de- velop bed-sores. They usually may be prevented by proper care of the skin, allowing no folds or creases in the bed-clothes (the pa- tient may lie on a blanket instead of a sheet), with frequent changes of posi- tion, and use of air-pillows, rings, water-beds, etc. Scrupulous cleanliness is most important, keeping the skin dry (in cases of involuntary dejections) and protecting it after use of stimulating lotions by dusting powders or soap plaster. The same measures are important in the treatment of a bed-sore when once it has formed. Fig. 20. — Dry gangrene from embolism; male, aged forty years. In December embolus lodged in brain, causing right-sided hemiplegia; in March (three weeks before photograph) embolus lodged in right popliteal artery. Death a few weeks later. No operation. Episcopal Hospital. NOMA 63 TIk' sl(tui;li should iu»t \)v cut ;i\vii\' until it is (|uito loose, and tlic undorlyiui;- ulcer should he dressiul with rather stinuilatiug- ointments. Constitutional treatment never sliould l)e nefi;lected. (J<>t tlie patient out of bed as soon as possible. Lon^jj continuance of a hirge bed-sore is a tremendous drain on the vitality and not infrequently is an indirect eause of death (exhaustion, sepsis, hemorrhage). Fig. 21. — Decubitus or bed-sore, in a patient, aged seventy-eight years; duration two months. The sloughs have been cut away. Episcopal Hospital. Fig. 22. — Cicatrices from bed- sores, in patient, aged twenty years, developing during typhoid fever five years ago. Episcopal Hospital. Hospital Gangrene {Sloughing Phagedena, Pourriture cV Hopital). — This scourge of military hospitals in former years probably is due to a specific microbe. Its clinical causes are crowding, bad ventilation, and generally unhj'gienic conditions. It is now almost unknown. It arose only in wounds, though the wounds sometimes were mere abrasions. The surface of the wound became dry, was covered with "a pulpy, ashen slough," and the circular shape and cup-like depres- sion of the wound were considered characteristic. By attention to hygiene its development usually may be prevented. It is most successfully treated by strong antiseptics (bromin, iodin) and scrupu- lous cleanliness. Patients affected should be isolated. x'Ymputation is scarcely ever necessary. Noma. — Noma is a gangrenous affection, almost exclusiA'ely con- fined to childhood, usually^ following the exanthemata (especially measles) or typhoid fever. Various bacteria have been found by different observers, certain forms of leptothrix being those most frequently present. As mixed infection, including saprophytes, almost always exists, the etiological relation of any one form is diffi- cult to determine. The disease affects the mouth (Gangrenous Stornatitis, Cancrum Oris) and the external genitals {Noma Pudendi), especially the genitals of female children. The ear and the rectum have also been affected. Whether in the mouth or the genitals, the disease usuallv starts on the mucous membrane, and in an incrediblv 64 DISEASES RESULT I XG FROM INFLAMMATION short space of time, perhaps three or four hours, a gangrenous ulcer an inch or more in diameter, may be i)resent. The first thing to attract attention is often a shiny red spot on the exterior of the cheek, the gangrenous ulcer having nearly perforated before being discovered. But if this complication be kept in mind the disease may be detected at an earlier stage from fetor of the breath, disinclination for food, etc., which will lead the nurse or attending physician to examine the mouth. The constitutional symptoms are slight, and the child, though listless, may continue to play with its toys until the hour of death. The alveolus may be involved, the cheek perforated, and frightful destruction produced in a very short space of time. Treat )ncnf should be prompt and vigorous; the child being anesthe- tized, a mouth gag should be introduced, the cheek everted, scraped with Volkmann's spoon, and the base of the ulcer thoroughly cauterized with fuming nitric acid applied by a stout stick; or acid nitrate of mercury may be used. If the cheek has been perforated, it is best to exer- cise the whole ulcer; and it may be necessary to excise a couple of inches of the alveo- lus (Fig. 23) . Free stimulation must be employed afterwards and the mouth kept constantly clean by the use of suitable washes. Death from exhaus- tion, bronchopneumonia, or pyemia, is the rule. The mor- tality varies from 70 to. 95 per cent. If the child recovers, a plastic operation may be necessary to restore the cheek. Similar treatment should be adopted in the case of Noma Pudendi, which is a much rarer affection. Aiahum. — This is a rare tropical disease, generally ending in gangrene, which usually is dry, affects the toes, and is almost exclu- sively confined to the negro race. Unna, according to Freeman (1906), regards it as a circular scleroderma which strangulates the toe. The affected parts appear as if tightly constricted by a string, and spontaneous amputation occurs after the lapse of an indefinite time. The disease may extend over ten years. Sjnnmetrical Gangrene. — Symmetrical gangrene is due to an obscure affection of the nervous system (Raynaud's disease), causing local asphyxia of symmetrical portions of the body, especially fingers and toes, probably from \'ascular spasm. As a rule only small super- ficial sloughs are formed. The symptoms are tingling, numbness, etc. Intermittent claudication may be an early sign. Little can be done in the way of treatment, except tonics and hygienic measures. Fig. 2-3. — Xoma following inta.^lt.-, iw a child, aged three years; duration one week. The gangrenous parts have been excised. Death. Children's Hospital. EMPHYSEMATOUS GANGRENE 65 Massage and hot baths, locally, may be of benefit. The patients usually recover, though successive attacks are usual. Noesske (1909) incises the finger tip down to the bone and applies a cupping glass; his theory is that the gangrene is due to stagnation of blood from venous obstruction; and that if a constant fresh su])ply of arterial blood is obtained by cupping, gangrene may be prevented until the spasm ceases. Emphysematous Gangrene {Traumatic or Spreading Gangrene, Gangrene Foudroyante). — Under this title three distinct affections are sometimes grouped: (1) True empliysematous gangrene, a form of gangrene due to infection with various gas-producing bacteria; (2) JNIalignant Edema, caused by a specific bacillus; and (3) Ordinary forms of gangrene, in which putrefactive changes are accompanied by gas production. The third form clearly does not belong here; but as the B. oedematic maligni is a gas-forming microbe, and as it is usually impossible to distinguish clinically infection due to it from that due to numerous other gas-forming microorganisms, there is no good reason why it should not be included in this section. When not due to the bacillus of malignant edema, emphysematous gangrene may be caused by infection with the Bacillus aerogenes capsulatus, B. proteus vulgaris, or B. coli communis, especially that first nanjied. The condition is almost invariably observed only as a complication of severe compound fractures or lacerated wounds, but occasionally has followed punctured wounds or even mere abrasions. On the third or fourth day after the injury the wounds do not discharge as freely as might be expected, and careful palpation will detect emphy- sematous crackling, which extends with alarming rapidity along the subcutaneous tissues (especially along the course of the large vessels), and may involve even the muscles. The skin becomes dusky, purplish, and mottled in appearance, and at a later stage the vesications and bullae, so characteristic of fermentative changes in already mortified parts, may develop. Incisions into the swollen and boggy tissues give exit to froth}'- fluid and malodorous gases. The patient sinks into a typhoid state; there is little fever; the pulse may be slow ; and death ensues a short time after the infection reaches the .trunk. The entire course of the disease may extend over only six or eight hours. The safest treatment is immediate amputation, high above the limit of the affected tissues. When this is impos- sible, free incisions should be made, the limb should be placed under constant antiseptic irrigation, hydrogen peroxide being preferred as the gas-forming bacteria are anaerobic; free stimulation should be administered, and everything possible should be done to obviate the tendency to a fatal termination. If amputation be done, the incisions should pass through absolutely healthy tissues, and the stump should be freely drained, and frequently dressed to detect the first evidence of recurrence in the flaps. I have seen only two cases of emphy- sematous gangrene: in the first case, under Dr. Neilson's care at the Episcopal Hospital, it followed compound fracture of the elbow in 5 66 DISEASES RESULTIXG FROM I X FLAM M ATI OX an old man; the gangrenous emphysema invaded the chest in three hours from its first appearance, before amputation could be done, and death followed a few hours later. In the second patient (Fig. 24), in Dr. Frazier's service at the Episcopal Hospital, a lad of sixteen, whose arm had been caught in revolving rollers and the skin squeezed off from above the elbow to the wrist, I successfully removed the arm at the shoulder-joint (Fig. 163) a few hours after the emphysema spread beyond the circular slough in the lower third of the arm. Fig. 24. — Emphysematous gangrene. Recoverj- after amputation at the shoulder-joint. Episcopal Hospital. Cellulitis. — Cellulitis is the term used to describe inflammation of the subcutaneous areolar tissue. This tissue, it is known, consists essentially of lymph spaces lined by endothelial or connective tissue cells; and it is now generally believed that these spaces have no direct communication with the lymph vascular system. Certainly cellulitis, as such, is clearly distinguished from lymphangeitis on the one hand, and from infectious dermatitis on the other. The causes are almost without exception bacterial infection, streptococcic rather than staphylococcic, usually from some abrasion or lacerated wound; but occasionally cellulitis, extending to the stage of suppuration, follows a confusion, a .sprain, or a simple fracture, the infection in ERYSIPELAS 67 such cases hciii.u- c()n\-c\<'(l to the phicc of h'sscncd resistance through the l)h)0(l-streain. ("elhihtis may also follow extravasaticMi of urine, of hlood, etc. Symptoms. — Tiie symptoms are those of inflammation, widely dilfused heneath the skin, not in it, and characterized esi)ccially by swellini;-. pitting on pressure, and the al)sencc of marked redness (Fig. 25). Treatment. — In the early stages rest procured by splints, by the use of a sling, by elevation of the part, together with local anodyne (lead water and laudanum) Fiu. 25. — Suppurative cellulitis of right forearm, eleven day.s' duration. From infected wound of wrist. Incised and drained through interosseous membrane. Children's Hospital. Fig. 20. — >Scar.^ from multi- ple incisions for cellulitis of calf. Episcopal Hospital. and antiseptic (corrosive sublimate and alcohol) applications, may suffice to eflfect a cure. As soon as evidences of suppuration occur, the overlying skin should be incised, in as many places as may be necessary, to give exit to pus, sloughs, etc. If the part affected is very tense, as is frequently the case in the forearm and hand, it is advisable to make free longitudinal incisions even before pus is formed, as the relief of pressure will enable the body tissues to combat the infection much more readily, and may prevent extensive sloughing. Fig. 26 shows the scars of multiple incisions for cellulitis of the leg. Erysipelas. — Erysipelas (a word usually supposed to be derived from two Greek words signifying red skin), known formerly as St. Anthony's Fire, is a specific inflammation aft'ecting the skin, the subcutaneous tissues, or both. Occasionally the mucous or serous membranes are involved. It is a specific disease clinically; and according to some authorities its cause, the Streptococcus erysipelatis G8 DISEASES RESULTING FROM INFLAMMATION (Fehleisen, 1884), is specific, in the sense that it causes no other disease; but equally good authorities maintain that it is not a specific microbe, but merely a variety of the common streptococcus, which for some unknown reason at certain times does not produce the usual symptoms. The seat of the inflammation is the lymphatic spaces of the skin itself (dermatitis) and of the subcutaneous tissues (cellulitis.) Erysipelas probably always is due to the presence of a solution of continuity of the skin or mucous membrane, through which the bacteria enter the tissues; but while it is not extremely rare in patients with lacerated wounds and compound fractures, it arises much more often as the so-called idiopathic variety, in which the wound probably is some insignificant abrasion. Especially is this the case with facial erysipelas, one of the most prevalent forms, the wound of entrance being probably some excoriation of the nasal mucous membrane. The eruption is characterized by its intense redness, which returns immediately on the removal of pressure; by its glazed or shiny surface; frequently by resicidation; by the raised, irregnlar, and well-defined borders of the inflamed area; and by the erratic manner in which it spreads (Plate I, Fig. 2). The inflammation is always most intense at the periphery of the patch, while the centre may begin to fade away very quickly. In simple erythema the patches have no ten- dency to spread, their edges are not raised, and vesiculation is unknown. In scarlatina the rash is not localized, it is neither well defined nor are its margins elevated above the surrounding skin; vesiculation is absent; it is a rare disease in adults; and a history of contagion may be obtainable. The dermatitis resulting from Rhits Toxicodendron is very difficult to distinguish from ery- sipelas, except by the history; the same is true of saprophytic dermatitis {erysipeloid of Rosenbach), due to local infection from decaying fish, etc. In ordinary cellulitis the redness is less, and the raised margins and vesicles of erysipelas are absent; and as the skin itself is not involved in cellulitis the disease does not affect the ears nor usually the skin over the tip of the nose, in which situations subcutaneous tissue is practically absent. In erysipelas, on the other hand, the pinna of the ear is prone to invasion. Symptoms. — The subjective symptoms are marked: these are pain, tingling, and a feeling of tension in the affected parts, which are exquisitely tender; there is high fever, rapid pulse, furred tongue, often delirium, and occasionally nausea, vomiting, and chills. As a rule there are no prodromal symptoms of importance. The eruption seldom lasts more than four days in one spot; from the original focus it may wander irregularly over the body, or may break out in an entirely different region. As the inflammation subsides, the skin becomes brownish in hue, the vesicles dry in the form of scabs, and the part appears more or less wrinkled. In facial erysipelas edema is marked, the eyes being closed and the nose and ears swollen < TREATMENT OF ERVSIPELASi 69 beyond all recoffiiition. There is a tendency for the disease to spread to the scalp; here the redness is less, anil the general ^-'-V:^V^::tt^ PULSE.?; 1 2 S 3 S 5 fe '3' S RESP. ^i 1 ?! ?! s? ?3 Fig. 28. — Puerperal septicemia; death. Episcopal Hospital. Fig. 29. — Diffuse purulent peritonitis from appendicitis. Death from terminal infec- tion (residual abscess). Episcopal Hospital. septicemia, except that the latter is little influenced by treatment. Sometimes by blood cultures it is possible to ascertain the presence of bacteria in the circulating blood during life; but as the number present in the blood may be few, a sterile culture is usually no proof that bacteriemia does not exist. The presence of staphylococcus albus in the culture usually is due to contamination from the skin. Treatment.^ — Treatment of septicemia, as already indicated, usually is impotent to stay the course of the disease. As pointed out by Lockwood (1896), at autopsy the bacteria are found even in the coronary arteries of the heart, and the persistent rapidity of the pulse may thus be accounted for. Nevertheless, as the diagnosis is sometimes impossible, except at autopsy, all the measures sug- gested for the treatment of toxemia should be employed in these cases, and it is possible that, in some patients, life may be saved. PYEMIA 73 Park speaks favorahly of the use of rngnenUnn Crede, which is absorbed through tlie skin; and he tliinks benefit is derived from "tlie dissemination througliout the system of the antiseptic virtues of tlie silver itself." He also connnends the intravenous use of a solution of Crede's soluble silver (1 gram of silver in 1000 c.c. of water). Barrows has used formalin solution (1 to 5000) intra- venously with alleged benefit. Pyemia. — Nearly invariably this is associated with thrombosis and embi)lism (p. 237). A portion (embuhis) of the septic clot or a clump of bacteria from the original focus of infection becomes detached, and is transported in the blood stream to the nearest set of capil- laries, where it lodges (embolism). Once lodged, the bacteria present in the embolus produce suppuration in the new location, and a secondary or metastatic abscess is formed. The primary thrombus Fig. 30. — Temperature chart in pyemia; acute osteomyelitis of calcaneum; abscess of brain; death. Episcopal Hospital. usually is venous in location, and the detached clot naturally might be expected to be arrested in the pulmonary circulation; but for some reason this is not always the case, the embolus passing safely through the lungs and being arrested first bj' some portion of the systemic capillary network. Occasionally, when the embolus first is carried into the venous current it travels against the usual course of the blood, and lodges in some portion of the venous channels distal to the primary lesion. This process is known as retrograde embolism; it may occur in suppurations in the neighborhood of the vena cava, or in the face, the blood current in the angular artery flowing sometimes toward the brain and sometimes outward. If the primary lesion is in the distribution of the portal vein {e. g., the appendix), the first set of capillaries encountered by the embolus will be the hepatic, and multiple liver abscesses will result. When 74 DISEASES RESULTING FROM INFLAMMATION in the systemic circulation, many different regions and organs may become affected; metastatic abscesses in the subcutaneous tissues or joints are most easily detected; but those in the kidneys, spleen, liver, lungs, or brain sometimes may be diagnosed during life. The original focus may be any supjjurating or septic lesion. Burned surfaces and suppurative lesions of bone are among the commonest causative conditions. Symptoms. — The symptoms are those of septicemia, with certain important modifications. The temperature is typically irregular"; its variations are extreme, and the absence of jjeriodicity is charac- teristic (Fig. 30). The highest temperature (104° to 106° F. or higher) on one day may be at a certain hour in the afternoon, whereas the next day the temperature may reach its highest point in the morning or not until late at night; or hyperpyrexia may be absent for an entire day or so. Chills are frequent, immediately preceding the fall of temperature, and are often indicative of the lodgement of an embolus, which may be attended by sudden pain. DAY OP MONTH 25 2(i 21 28 29 104 .103 I o ::i02 HlOi < slOO 99 98 fl7 ~ - z z -J -J -J z - - - — < — L ^ L 1— U H H - --\ .. - R i^J 1. ! 1 = ^ 1— _ _ -t ;--i\/V A- ■ r^ — — ' — ' , jL. , 1 , _ - 1 ■ ■ I — ' — ' ~ ~ ~- ~ PULSE g: -; V. 7 t s o s s RESP. »l lsl ls| |si s g ?; ?: ?, Fig. 31. -Sapremia; rapid fall of temperature after evacuation of retained secundines. Episcopal Hospital. Prognosis. — The prognosis is extremely bad; a few patients, in whom the infection seems to be attenuated and the course of the disease chronic, occasionally recover. The staphylococcus is more frequently the causative organism than the streptococcus. Treatment. — Treatment is the same as for septicemia. Constant vigilance is needed to detect and locate metastatic abscesses, and they should be drained immediately, when accessible; and unless the patient is so ill that a formal operation will hasten his death, the surgeon should not hesitate to evacuate abscesses of the internal organs or even the brain. By ligating or excising the main venous trunks leading from the original lesion, the infection sometimes may be successfully localized (internal jugular in mastoiditis, ovarian in parametritis, angular in facial phlegmon, etc.). SAPREMIA 75 Sapremia. W'Iumi dead or dying tissue is in contact with li\ing cells, the jjtoinains and other ))oisons elaborated by the saprophytic bacteria which infest the former may be absorbed into the i)atient's body, and thus produce the usual syni])tonis of toxemia. When healinji; in the wounded area has j)rogressed to the stage of granu- lation, little if any absorption occurs; but injudicious probing of a gramilating wound may destroy this barrier, and evidences of sepsis will follow. It is sometimes imjxjssible to distinguish mild grades of sapremia from asei)tic fever, or from a slight toxemia due to absorption of the products of pathogenic bacteria; but usually it is easy to differentiate clinically between sapremia and toxemia, because 2 3 4 5 *i 7 8 9 10 II 12 13 14 15 10 17 i% 1!) 20 21 22|23l24 25 Fig. 32. — Tuberculosis of hip; hectic temperature arrested by excision of hip. Orthopsedic Hospital. in the former case there always is some dead and decaying tissue present, where the putrefactive bacteria multiply. If this material is removed, the bacteria are removed with it, absorption ceases, and health is restored. Sapremia is seen in its typical form in puer- peral cases, absorption occurring from the retained secundines (Fig. 31). Hectic fever, which is classed by Park as chronic sapremia, is most typical in patients wdth tuberculous bone disease, where siruises exist, and as a consequence the decaying bone has become infested with saprophytic bacteria. Fig. 32, from a patient with coxalgia under my care at the Orthopedic Hospital, in the service of Dr. Harte, shows hectic fever promptly arrested by excision of the hip. CHAPTER III. MODIFIED FORMS OF INFLAMMATION (SURGICAL INFECTIONS). Situated pathologically half way between pure inflammation and neoplasms, exists a group of surgical diseases usually described as the infections gramdornas. This term implies that although the lesions are definitely known to be caused by speciiic microorganisms (which is not the case with tumors), yet the tissue reaction to these specific irritants is characterized rather by cell accumulation than by actual destruction of tissue by suppuration. It is as if the irritant were too timid to provoke vigorous resistance, yet too enduring to be overcome at the first onslaught; the tissues of the body seem either indifferent to the invasion, or unable to continue the struggle with the success which usually attends their warfare in acute inflam- mation. While the more important of these modified forms of inflam- mation (Tuberculosis, Syphilis, Actinomycosis) partake of the nature of subacute or chronic reactions, there are others (Anthrax, Glanders, Tetanus, Hydrophobia) in which the reaction is acute, and the lesions less circumscribed, but which it is nevertheless convenient to discuss in the same chapter. CHRONIC INFECTIOUS SURGICAL DISEASES. Tuberculosis. — Surgical tuberculosis includes all manifestations of this infection, wherever situated, which are amenable to surgical treatment. The specific cause of the disease, the B. tuberculosis (Koch, 1882), gains entrance to the body usually through the digestive or the respiratory tract. It has been held by good authorities that the bacilli may pass through the respiratory or intestinal mucosa and produce no lesions in it. The bacilli lodge most frequently in the lung; next most frequently in the lymphatic nodes — cervical, bronchial, or mesenteric. Occasionally infection occurs through an open wound; inoculation with tuberculous material while dissecting produces the so-called anatomical tubercle. The bacillus is omnipresent in civilized life, and it is by no means improbable that it lives as a parasite in the bodies of most apparently healthy persons. It is always at hand to attack any place of lessened resistance, and to explain its prompt appearance in such locations it is usually necessary to assume that it was present previously, though latent, somewhere in the patient's body. Scrofula, formerly con- sidered a distinct disease, is now generally recognized as identical SURGICAL TUBERCULOSIS 11 with tuberculosis; it is, liowover, as DaCosta says, a useful term to describe the habit of body of such as are easily infected with tubercu- losis; in other words, scrofula may be considered tuberculosis in its primary, latent state. Tuberculosis is most often i)rimary in the lungs, digestive tract, lymph nodes, urinary and sexual organs, and the bones. Surgical tuberculosis, which is said usually to be secondary to an inconspicuous lesion of the lungs, is seen especially in the lymph nodes, the bones and joints, the sexual organs, peritoneum, etc.^ Pathology. — The local lesion produced by the B. tuberculosis is called a iuhcrde; its proper adjective is tnhercidous ; and it should be distinguished from a tubercule, a term which describes the anatomical form of the lesion of a skin eruption which is called tubercular, but which is in no way connected with tuberculosis. When the B. tuber- culosis begins to proliferate in the tissues, its first effect is to exert chemotactic action upon the connective tissue and endothelial cells in its immediate vicinity. It does not exert positive chemotaxis upon the leukocytes circulating in the blood, and leukopenia not leukocy- tosis is the rule; but the number of circulating lymphocytes may be relatively increased. Locally, as the tissue cells accumulate, their appearance changes, the cells swell up, become pale, and resemble epithelial cells so closely that they are widely known as epithelioid cells. This accumulation of epithelioid cells around the tubercle bacilli causes an anemia of the central area, and the epithelioid cells themselves gradualh' suffer from lack of nourishment, and, instead of actively dividing and multiplying their number as at first, they seem to be unable to carry the process of reproduction further than the stage of division of the nuclei; so that among the epithelioid cells there soon appear two, three, or more large cells with multiple nuclei, arranged around the periphery or at the two poles of the cell— the so-called giant cells. In the area immediately surrounding the giant cells and epithelioid cells, the lymphocytes accumulate; while the centre of the tubercle is composed of tissue and cellular debris under- going caseous degeneration, which is the form of anemic necrosis particularly characteristic of tuberculosis. Some phagocytosis exists, but it sometimes seems as if the tubercle bacilli continued their exist- ence as parasites even within the cell bodies of their victim: they are most apt to be seen within the giant cells; they are frequently present in the epithelioid cells; but are said never to be found within the lymphocytes. The histological tubercle, thus, maj' be represented diagrammatically (Fig. 33) as composed of three portions: (1) a cen- tral caseous or necrotic area, in which may be a giant cell, its own centre showing commencing caseation; (2) the epithelioid cells sur- rounding the caseous centre, and (3) the peripheral aggregation of lymphocytes. * Some modern investigators believe that the bovine form of Tubercle bacillus is responsible for "surgical tuberculosis," while the human form is that usually found in the lungs. 78 CHRONIC INFECTIOUS SURGICAL DISEASES The products of the tul)ercle bacillus, spoken of generically as tuberculin, are not very well understood; it seems probable, never- theless, that caseation is induced by the toxins set free from the bodies of the bacilli when they die, but that the irritant action of the living bacilli is only sufficient to provoke cell accumulation and multi- plication. These various products of tubercle ])acilli usually exist in greater or less amount in the body fluids and excretions of animals suffering with tuberculosis; and, when injected into other animals afflicted with tuberculosis, the tuberculin contained in them produces a characteristic reaction which may be used for the purpose of diag- nosis- (p. 81). Fig. 33. — Section through a tubercle. Upon the margin of the tubercle lymphoid cells may be seen; in the centre epithelioid cells and a giant cell. (Lexer-Bevan.) The primary tubercle may be replaced by granulation tissue formed from the surrounding connective tissue cells, and healing may occur in a manner similar to that of simple inflammation. Or the "pyogenic membrane" may isolate and encapsulate the tubercle, and thus the disease may be arrested; calcification is a frequent sequel. On the other hand, some of the bacilli may escape through the cordon of epithelioid cells on guard, and, settling in a neighboring portion of the tissues, they may there proceed to form a new tubercle; and as many more tubercles are formed, the area may become visible to the naked eye, and the centre of the entire mass may be seen as a caseous nodule surrounded by comparatively healthy tissue (Fig. 34). Two S VRCKW L T [ BER( ' l' LOS IS 79 processes may thus be initiated — either productive or dejjenerativc; the former gives rise to tiil)crculi>n.s (fun (/on ft) ij;ran illation tissue, fre- quently descril)ed as the tuberculous gumma (Figs. 35 and 37), because .V M ^.>.^^...::^ Fig. 34. — Cross-section of tuberculous testicle, showing areas of caseation. Skin adherent. One sinus has been divided in the section. From a patient in the Episcopal Hospital. it is very difficult to distinguish it histologically from the gummas of syphilis, actinomycosis, etc.; whereas the degenerative changes result in the formation of a cold abscess, so named to distinguish it from the Fig. .35. — Tuberculous gummas of leg, in a baby, aged eight months. Children's Hospital. ordinary abscess of inflammation, which is characterized })y its heat. Tuberculous granulation tissue has a great tendency to displace all normal tissues with which it comes in contact: in bones it causes the 80 CHRONIC INFECTIOUS SURGICAL DISEASES disappearance of the normal osseous structure; in joints it grows upon the synovial membranes, producing fibrous ankylosis; in tendon sheaths it spreads along their course, gradually invading the tendons and in time causing their entire disappearance. The degenerative changes, which by the process of coagulation and liquefaction necrosis change tuberculous granulation tissue into cold abscesses, are probably due, as already pointed out, to excessive destruction of tubercle bacilli with liberation of their endotoxins, and to the action of fer- ments set free by the death of cellular protoplasm. When the cheesy pus finds an exit for itself, the tuberculous abscess is converted into a tuberculous sinus, or if the walls of the abscess cavity are unable to collapse, as in bone, and often in the lungs, a tuberculous cavity remains. As the tuberculous sinus heals, it becomes converted into a ^^^KtSitmSk-^^ ^-\ t-i Fig. 36. — Scrofulous ulcers, one month Fig. 37. — Tuberculous dactylitis(tuber- duration. Two months after incomplete culous gummas of fingers). Children's operation for recurrent tuberculous cervical Hospital, adenitis. Episcopal Hospital. tuberculous ulcer (Fig. 36). It w^as once hoped that by the admin- istration of tuberculin to tuberculous patients their tuberculous lesions could be disintegrated and caused to discharge; but, unfortunately, it has been found that sudden disintegration of tuberculous foci is more apt to be followed by acute generalized miliary tuberculosis, which may be succinctly described as tuberculous pyemia. Any secondary infection, moreover, of a tuberculous focus, is prone to aggravate the condition by weakening the protective layer of epithe- lioid and lymphoid cells which surround the tuberculous area. The great danger when any cold abscess discharges is that of secondary (pyogenic) infection. As Calot says, the opening of a cold abscess is the opening of a door by which death soon enters. Diagnosis. — The detection of the tubercle bacillus in the lesions renders the diagnosis certain; but in the vast majority of cases this SURGICAL TUBERCULOSIS 81 is not rociiiisite, as the clinical appearances are quite sufficient to justify the diagnosis of tuberculosis. The indolence of the reaction, the slow course of the disease; the characteristic cheesy material discharged from the sinuses; the absence of leukocytosis in uncom- plicated cases; and the general ai)pearance of the patient; these all, when conibiiu'd in one indi\idual, make the actual detection of the tubercle bacillus an unnecessary task in most cases of external tuber- culosis (bones, joints, lymph nodes, skin, etc.). In tuberculosis of certain internal organs, especially the kidney, it is highly desirable to detect the bacilli in the excretions. Another aid to diagnosis is the titherculin test (p. 78) : old tuberculin^ is that generally used, the initial dose in adults being one-tenth of a milligramme (0.0001 gramme) hypodermically; this rhay be increased at subsequent injec- tions to 1 and even to 5 milligrammes. The hyi)odermic use of tuber- culin gives reasonably accurate results, and I prefer this method to the conjunctival test of Calmette, or to the inunction of jMoro's tuberculin ointment. The cutaneous reaction of v. Pirquet is usually to be preferred in children (under twelve years of age), but as it appears to indicate the existence of latent or healed tuberculosis (very rare in children) quite as readily as an active focus, it is not regarded as so accurate as the hypodermic test for adults. The hypodermic test, unless repeated, causes reaction only when there is an active focus in the body; but it does not necessarily indicate that the lesion suspected is tuberculous. If, however, its use causes an exacerbation of symp- toms in the suspected lesion {focal reaction) there can be very little doubt of its tuberculous character. After the hypodermic injection has been given, the patient's temperature should be recorded every two hours for a period of 24 hours: a positive reaction, indicating the presence of tuberculosis, consists in an abrupt rise of temperature to 101° or 102° F., occurring usually about the twenty-second hour.- Sometimes a chilly sensation is experienced as the temperature begins to rise. If the first injection is negative, a second and even a third may be given, gradually increasing the dose. I have never seen any untoward result. The reaction is positive in most cases of tuberculosis not in advanced stages; it is usually negative when secondary infection is present, with amyloid changes in the viscera and a hectic temperature; but in such cases the diagnosis is easy enough without this test. Indeed it is quite useless to employ a tuberculin test if the diagnosis can be made clinically. In v. Pir- quet's method three small areas on the arm are abraded, and into ^ Old tuberculin is a filtrate of a concentrated glycerin extract of tubercle bacilli; it is possible that some of the bacilh may not be excluded by the filter; to obviate this danger Koch has prepared two new tuberculins: of these Tuberculin Oberst (T. O.) is the supernatant liquid obtained by centrtfugalization of a concentrated glycerin extract of tubercle bacilli; the sediment which forms, containing the bacilli themselves, is ground up and again centrifugalized, and forms Tuberculin Rest (T. R.). T. O. resembles old tubercuhn, and may be used instead of it in diagnosis; T. R. is used in treatment. 2 An earlier rise, especially within a few hours of the injection, probably is due to some contamination. 6 82 CHRONIC INFECTIOUS SURGICAL DISEASES one or two of these the tubercuUn is rubhed; the other abrasions being used as controls. On the second or third day, in tul)ercu- lous cases, the infected area shows a characteristic, erythematous, papular, and even vesicular eruption. Treatment. — Constitutional and hygienic treatment are quite as imi)ortant in surgical as in medical tuberculosis. The majority of patients with surgical tuberculosis are children of a school-going age. It is better for them to give up school for one or two years, until their constitution is strong enough for them to conquer the dis- ease, than to attempt to keep up in their classes and grow physically worse and worse. It may not be possible for them to sleep in the open air, but they can at least sleep with all the windows in their room open, and be out of doors as much as possible during the day. In hospitals provided with suitable roof-gardens, where the patients may be kept in the open air practically twenty-four hours out of the twenty-four, it has been found that operative treatment is scarcely ever-required. In institutions where it is impossible for one reason or another to keep the bed-ridden patients out of doors constantly, it usually is quite possible for their beds to be wheeled out of doors and left out from 7 a.m to 7 p.m. It is by no means necessary to have a hospital in the country for these patients: porches and balconies, even if roof-gardens cannot be obtained, will accomplish the same results in the most thickly settled parts of the city. Hand in hand with the open air treatment must go full, wholesome diet, especially milk and eggs; and the only medicine usually required is cod liver oil, which seems to act better than any otiier remedy in increasing the appetite and causing the patients to put on flesh. In the rare cases where it does not do good, the syrup of the iodide of iron, the compound syrup of the hypophosphites, or other remedies, may be tried. Locally, I am convinced that tuberculosis of the soft parts demands a different treatment from that of bone. In the latter case such re- markable results are obtained in children by local rest, without opera- tive interference, that I am extremely conservative in urging any other surgical treatment: the use of plaster casts, braces, weight extension in bed, together with proper hygienic treatment, will cure nearly all patients in whom these methods are adopted early. As regards tuberculosis of the soft parts (lymph nodes, generative and urinary organs, peritoneum), however, local rest is usually impossible to secure, and I feel sure that better results are obtained ])y radical operation, removing the entire disease; and when this is impossible, as in the abdomen, at least remoA'ing the primary focus. The local treatment adapted to each form of tuberculosis will be pointed out when the surgery of those portions of the body is discussed. Syphilis. — This is an infectious granuloma due to inoculation with the Treponema pallidum {Spiruchata pallida), a parasite described by Schaudinn and Hoffman (1905), and obtained in pure culture iii 1911 by Xoguchi and by Hoffmann. PATHOLOGY OF SYPHILIS S3 Pathology. — This organism usually gains access to the tissues through sonic abrasion or excoriation of the skin or mucous mem- branes, being inoculatecl directly from a sore in another person sull'cr- ing from syphilis {'uiniicdiatc cunfaffiun). Occasionally vicdiaic con- tagion occurs, the virus being transmitted by means of soiled towels, eating and drinking utensils, etc. When inoculated, there follows a period of inruhaiion, averaging from three to five weeks, during which the microbes multii)ly at the site of primary in\asion, and are carried by the lymi)h channels to the nearest lymph nodes; so that by the time the local reaction appears at the site of original inoculation, the disease is already diffused in the patient's body. Neisser found the blood contained the virus as early as the fifth day after inoculation. The local reac- tion (chancre) resembles the tubercle in some ways: a col- lection of round cells occurs, and there may be a few giant cells present; but the chancre is particularly characterized by the great proliferation of the endothelial cells lining the capillaries. By proper stain- ing methods the presence of the Treponema pallidum may be demonstrated; otherwise the histological picture is not regarded as conclusive, though endothelial proliferation is always suggestive of a syi)hi- litic lesion. The chancre is situated in the true skin (derma) ; usually when first seen, exfoliation of the overlying epidermis has occurred, converting the primary lesion into a superficial erosion; in some cases the local reaction is much more marked, and the deep or Ilunterian chancre develops. Usually very soon after the appearance of the chancre, enlargement of the regional lymph nodes may be detected; and not infrequently the lymphatics leading to these nodes are palpably enlarged. There follows the second period of incubation, lasting on an average about six weeks; during this period the virus of the disease is spreading past the first group of lymph nodes, and is carried by the blood-stream all over the patient's body. Various prodromal symptoms, such as fever, malaise, headache, vague "rheumatic" pains, etc., may be experienced during this time. As in typhoid fever, the infecting organisms lodge first in the cutaneous capillaries, and the well known rashes of syphilis (secondary lesions, syphiJodermas) are produced; at the same time the lymph nodes all over the body become enlarged, especially the posterior cervical and epitrochlear Fig. .38. — Treponema pallidum (SpirochiBta pal- lida) : a, red; b, white-blood corpuscles. 84 CHROXIC IXFECTIOUS SURGICAL DISEASES groups. The lesions of this secondary period are not confined entirely to the skin; the mucous membranes usually are also affected, the eruption appearing in modified form in the mouth, the fauces, and the vagina. The histological picture of these secondary lesions presents nothing pathognomonic of syphilis; but the proliferation of the endo- thelial cells lining the bloodvessels is usually sufficient at least to sug- gest the S3"philitic nature of the disease, and the specific organism usually may be detected by smears made from the ulcerated sores. Still later, more or less typical lesions appear in the deeper structures and in the internal organs. These, which are known as gummas, are characteristic of the third stage of syphilis; they consist essentially of an aggregation of round lymphoid cells, with an occasional giant cell at the periphery of the lesion; bloodvessels are less conspicuous in the tertiary than in the secondary lesions of sj'philis. The Tre- ponema pallidum rarely can be found in these tertiary lesions; it is practically never to be detected in those with pyogenic infections. As in the case of tuberculosis, so here, there is a marked tendency for the centre of these lesions to undergo various forms of degeneration, of which the hyaline and fatty are the most usual. Instead of the cheesy pus so characteristic of tuberculous suppuration, the product of syphilitic suppuration is known as gummatous pus. In tertiary as well as in secondary lesions, there is a marked tendency for the disease to be productive at the periphery of the lesions, while degenera- tion occurs in the centre. This is thought to account for the charac- teristic serpiginous form of some of the later skin lesions (Fig. 930). The tertiary lesions of syphilis heal by granulation and cicatrization, with resulting deformity from contraction of the scar-tissue. The scars are typical, both on surfaces and in the interior of organs — in the former situations the regular outline, circular form, and depressed, shiny base of the cicatrix are nearly pathognomonic of a former syphilitic lesion; while the radiating, star-like cicatrices in the internal organs usually may be recognized at a glance. Secondary infection with pyogenic bacteria is a frequent occurrence in gummas; this hastens the destructive process and increases the subsequent deformity. No tissues are exempt from the ravages of s^'philis. The favorite seats for the secondary lesions are the skin, mucous membranes, and iris. In tertiary syphilis the periosteum, bones, and joints; deep sub- cutaneous tissues; palate and nasal structures, iris, retina, and choroid; the internal and generative organs; and the nervous system; are those most usually affected. This brief sketch of the pathology of syphilis will suflBce for the present chapter. The clinical aspects of the disease, as well as the treatment, will be discussed in Chapter XXVI, while important syphilitic lesions of the various, parts and systems of the body will be described in chapters devoted to regional and systemic surgery. Actinomycosis. — The cause of this disease commonly is known as the Ray Fungus, from its appearance under low powers of the micro- scope (Fig. 39); but scientists differ as to whether it shall be classed ACTINOMYCOSIS 85 Fig. 39. — Grains of actinomyces from human pus. X 450. (Marwedel.) with the moulds (liyphomycctes) or with bacteria (schizomycetes). This organism is found growing on hay and .straw, and also in the ground, whence it may he incorporated in growing vegctal)lc matter. It was first observed by von Langcnbcck in 1S45, in the pus from a patient with caries of the vertebne. Formerly, instances of tiie dis- ease were considered sarcomatous or carcinomatous in nature. In cattle the ray fungus is a frequent source of disease (lumpy jaw, swelled head) ; but few cases have been obserxed in which actual trans- mission from animal to man has occurred. The usual source of infec- tion in man is believed to be chew- ing of diseased grain; but J. H. Wright (1905) claims that the ray fungus is quite commonly found in healthy mouths, both of man ami beast, and asserts that the action of the cereal is merely to prepare a locus minoris resistentioe where the fungus can develop. Pathology. — Like the other in- fectious granulomas, actinomycosis is characterized by a local produc- tive reaction. There is very little tendency to necrosis; but in man- kind secondary infections are the rule, and hence suppuration is much more frequent than in the lower animals. The cellular infiltrate surrounding the focus of disease consists of small round cells, giant and epithelioid cells; conversion into granulation tissue occurs, and this tends to cicatrize. The dis- ease is prone to extend along sinuous and branching tracts, suppura- tion occurring in the centre, while the sinuses are lined with the granulomatous tissue. In the pus discharged from these tracts, the colonies of the fungus are visible to the naked eye, as minute yellow granules; these impart to the fingers a gritty sensation due to the presence of calcareous salts. The disease is chronic, and unless vital parts are attacked, life may l)e prolonged for years. Occasion- ally metastatic foci are developed through the blood-stream; but the disease never extends by the lymphatics, and enlargement of the regional lymph nodes usually is an indication of secondary infection (Frazier). Symptoms. — Four distinct varieties of human actinomj'cosis are recognized: the oral, the pulmonary, the abdominal, and the cutaneous. The origin of the first has already been described; from the tissues of the mouth proper, the jaws, the cheeks, the neck, and even the skull and brain may be invaded. The pulmonary form, due to inhalation, usually assumes the character of a low grade basal pneumonia; pleural effusion and invasion of the thoracic parietes are frequent. The spine may be involved, and the cold abscesses formed may closely simulate those of tuberculosis. Abdominal actinomycosis, especially 86 CHRONIC INFECTIOUS SURGICAL DISEASES frequent in the neighborliood of the cecum, is of the hyperplastic type, abscess formation and intestinal perforation being rare; the dis- ease tends rather to produce adhesions to the parietal peritoneum, and to invade the a})dominal wall, producing there the characteristic lesions seen whenever the skin is invaded. Cutaneous actinomycosis ' frequently may be diagnosed without microscopical examination of the pus; the sinuses, with the involuted, hypertrophied skin; the chronic and nearly painless course of the disease; the typical "board- like" induration, sharply outlined; and perhaps the presence of hard cords under the skin running from the main lesions out in various directions; all make a picture which is not readily mistaken for an^'thing else. Diagnosis. — This must be made from malignant tvmors, which may be closely simulated by the hyperplastic form; from osteon/ i/elitis and tubercniovs lesions of bones and joints; from inflamed sebaceous cysts of the face (Fig. 40), which, as pointed out by Lexer, some- times bear a striking resemblance to actino- mycosis; and from gummatous and other syphilitic lesions. Treatment. — If complete extirpation is possible, this should be done; but in most cases the surgeon must content himself with freely opening all the sinuses, removing the granulation tissue with A'olkmann's sharp spoon (Fig. 451), cauterizing the remaining tracts w ith the actual cautery or some chem- ical caustic (chloride of zinc 10 per cent.), and packing the wounds with iodoform gauze. Iodide of potassium is said to have a remarkable effect, administered in large doses for two or three weeks at a time and then discontinued for one week. Bevan (1908) has used cupric sulphate pills, one quarter of a grain, thrice daily, with marked benefit; he also irrigates the wound with 1 per cent, cupric sulphate solution. This method is based on the agricultural treatment of the diseased grain. Out of door life, and hygienic measures, as for tuber- culosis, are of almost equal importance with topical remedies. Madura Foot. — Madura foot, first observed in Madura, India, in 1712, is occasionally seen in America. It is due to a fungus closely resembling the actinomyces; one foot only is involved as a rule; very occasionally the hand is affected. A painless swelling forms on the sole; softening and suppuration follow. The course is chronic. Fistulse form, heal, and again break open. Finally all the structures of the foot are invaded. Amputation is the best treatment. Blastomycosis. — This is a surgical infection whose chief lesions are manifested on the skin, caused by organisms of undetermined Fig. 40. — Multiple seba- ceous cysts of the face simu- lating actinomycosis. Epis- copal Hospital. ANTIIh'AX 87 l)i(>l()j;ic'al position, known as l)laston)yc('tos. A few cases of systemic infection have also heen reported. According to He\aii (HKISj "tlie cutaneous lesions have l.een mistaken most often for \ (Trucous tulicr- culosis, less often for syphilis, and occasionally for epithelioma. Tuherculosis is the disease which is most apt to he confused with systemic blastomycosis." The diagnosis is best made by micro- scopical examination of the pus from the cutaneous lesions, or by excluding the existence of tuberculosis by the usual tests. Bevan thinks potassium iodirle is the most valuable remedial measure; he gives as much as OOO grains a day, well diluted. Cupric sulphate has also been used. Hygienic measures are important. In advanced cases the lesions must be treated surgically, by excision, curettement, cauterization, etc. Rhinoscleroma.— Uhinoscleroma, a chronic infiltrating, j)roductive infection of the nasal mucous membrane (rarely of the pharynx, larynx, and hard palate), is almost unknown in this country, though common in Austria and southwestern Russia. It is possibly due to a diplobacillus (v. Frisch, 1SS2). It is highly destructive, invading all surrounding tissues, and clinically resembling other infectious granu- lomas. Excision is the best treatment; when this is impossible enough of the growth should be removed to facilitate breathing. ACUTE INFECTIOUS SURGICAL DISEASES. Anthrax. — This disease, due to infection by the B. anthracis (Davaine, 1873; Koch, 1877), is common in sheep, horses, etc., and may be transmitted to man directly, or through contagion from wool, hides, etc. Invasion occurs through abrasions of the skin or mucous membrane; or through the respiratory or the intestinal tract. The period of incubation is one or two days. The local reaction consists in a cellular and serous exudate, producing marked edema, with a tendency to central necrosis. Eighty-five per cent, of cases affect the head, face, and neck. In severe cases anthrax bacilli enter the blood current, and bacteriemia results; as the bacilli are too large to pass through capillaries of ordinary size, they are arrested at various places and produce car))unculoid lesions in these new situations. The cntatieoiis form {Charbon; malignant pustule) is characterized by the formation of a papule, changing into a vesicle, surrounded by an edematous area (Figs. 42 and 43) ; no pus is discharged. The vesicle dries up, a scab forms, central necrosis occurs, the black central core completing the typical picture. The pain ceases, and in mild cases the slough may be cast off, and spontaneous healing occur. In severer cases, lymphadenitis and angeioleucitis develop, toxemia becomes profound, and death may ensue in a few days. The jjulnwnary form {ivoolsorter s disease) is of slight surgical importance; SO per cent, of patients are said to die by the fifth day. The intestinal form is characterized first by symptoms of ptomain poisoning; then by hem- orrhages; and finally the lodgement of the bacilli in the cutaneous 88 ACUTE IXFECTFOI'S SURGICAL DISEASES capillaries produces a widespread carbunculoid eruption soon followed by death. Diagnosis. — Anthrax is to be distinguished from other surgical infections by the history of exposure to the infecticni; by the local edematous reaction, with central black core; by the absence of pain S<^' Fig. 4:1. — Anthrax bacilli. Spore formation. From an agar culture twentj--four hours old. About the margin of the photograph are a number of free spores. X 600. (Karg and Schmorl.) Fig. 42. — Aiiriiiax ',i face Episcopal Hospital. Fig. 4.3. — Anthrax of face. Black slough in centre of edematous area. and suppuration; and finally by detecting the bacilli in smears made from the lesion. Prognosis. — ^The mortality has \aried from 25 to 33 per cent, in collected cases (Frazier, 1906); but by appropriate treatment it may be reduced to 6 per cent. GLAXDERS 89 Treatment. — Excision should be done wlicii possiljlc, iis is usually tlu; case wlii'n an (.'xtrcniity is allcctc^^ in sneezing, or by means of the purulent '^ ^\\<.ll^ discharge from other sources. Occupation in \\ tf^^"" ^M stables is therefore a predisposing cause. | *< '^'^i* i*^ J "^ Invasion occurs by inoculation of an abrasion ' v/' *]};» ** of the skin (farcy); or of the nasal or buccal \ S\, *' ..^'^ \ mucous membrane {glanders); or through \ {> ' /''j the respiratory or digestive tract. The result- ing infection runs an acute (very rarely a gia^,ders^fi37ci?luf mllleif chronic) course. The local lesion somewhat (Abbot.) resembles a tubercle; the regional lymphatics are afi'ected early, and dissemination through the blood-stream is rapid. The lesions, wherever situated, are specially characterized by their tendency to rapid suppuration. Along the lymphatics, small harfl nodules (farcy buds) appear, and soon suppurate. In the lungs multiple foci, which soon suppurate, are produced. A diffuse pustular eruption, sometimes mistaken for smallpox, frequently occurs in the skin (Fig. 45j . In the subcutaneous tissues and muscles, hard, movable nodules appear, especially in the biceps, flexors of forearm, rectus abdominis, and pectoral muscles; the nodules soon suppurate. Bones may be invaded, and by implication of joints pyarthrosis may occur. Symptoms. — The period of inculcation varies from three to seven days; malaise and indefinite typhoidal symptoms are the first to appear. In glanders, naso-pharyngeal granulomas are the earliest lesions, with ulcerations, causing sero-sanguineous catarrh; then pneu- monic signs; and finally the cutaneous rashes, and subcutaneous and muscular nodes. Leukocytosis usually is not marked. In farcy, the skin affected becomes intensely inflamed; farcy buds appear along the lymphatics and soon suppurate; while the later symptoms resemble the last stages of glanders. 90 ACUTE INFECTIOUS SURGICAL DISEASES Diagnosis. — In the acute cases this is rarel}' made l)efore death. The patient's occupation, microscopical examination of the discharges, and a negative Wi(hd reaction, are factors which may indicate the nature of the malady. By the time the characteristic nodes ai)pear, the patient is beyond the reach of treatment. In animals the disease may be detected by the "mallein test" (similar to the tuberculin test, p. 81). The chronic form of the disease resembles the late stages of syphilis. Fig. 45. — Pustular eruption in human glander.s. (Dr. Zeit's case.) Prognosis. — The disease is extremely fatal (85 to 90 per cent, of cases). Death occurs in from one to three weeks. Treatment. — Isolation should be immediate, as the disease is easily convej^ed by both immediate and mediate contagion. If an extremity be affected, amputation is indicated. Localized lesions elsewhere should be excised when possible; at least they should be opened and treated with rigorous antiseptic methods. Curettement and scrub- bing are liable to disseminate the bacilli. Hygienic treatment often is all that is available. Tetanus (Lockjaw). — This disease, characterized by tonic and clonic convulsions, and especially by locking of the jaws, is caused by the B. tetani (Fig. 46), discovered by Nicolaier in 1884, and obtained in pure culture by Kitasato in 1889. The bacillus is anaerobic and is found especially in garden soil, barnyards, stables, etc. It probably normally infests the intestinal tract of cattle, and is re-deposited with their dung. So long as the mucosa of their gastro-intestinal tract is intact, they are not liable to infection by this channel. Horses are particu- larly susceptible. Tetanus appears to be endemic in certain localities. TETANUS 91 Fig. 40. bacilli, showing spore (Kitasato.) Inoculation occurs only tlirouw>." *!^B i^i the newborn operation should be postponed until it is apparent that the child's constitution is otherwise suf- ficient to support life. Terato-blastomas.^ — These tumors, derived from pluri-potential cells, comprise most of the so-called "mixed tumors" — tumors in which tissues are found which do not nor- mally exist in the organ or tissue affected. In the parotid, and sometimes in the submaxillary gland, cartilaginous tumors are not unusual; in the kidney such tumors rarely have more than one variety of aberrant tissue, and have received various names according to the predominant tissue — rhab- domyoma, adenosarcoma, etc. The tumor known as chorio-epithelioma (deciduoma) maligmnn belongs to this group; it is formed by neoplastic development of cells of the chorionic villi. The placerital mole is believed to be the early stage of such development; when the cells invade the uterine sinuses malignancy is evident and the deciduoma is present. The terato-blastomas, as well as the pure embryomas, often exhibit malignant characteristics, and are best treated by excision. Blastemas. — ^These tumors, forming by far the largest group of neoplasms, result from the independent growth of uni-potential cells. They are divided by Adami into two main groups, according as they are composed chiefly of cells arranged like epithelial, or rind, tissues (Lepidic tumors, Lepidomas), or of cells arranged like the stroma or pulp of tissues and organs {Hylic Tumors, Hylomas). The charac- teristic of all epithelial structures (skin, mucous mem])rane, endo- FiG. 53. — • Sacro-coccygeal tera- toma. Italian girl, aged six months. Pennsylvania Hospital. LIPOMA Wi tlu'liuin) is that tlu' cells jirc ])l;i(r(l closely toj^ctluT, there heiiiij; ;in ahseiice ot" deliiiite stroma hetween the indixidiiai cells, and no blood- vessels penetrating hetween the \arioiis <;Ton|)s of cells. The ciiar- acteristic of all i)nli) tissnes (nerxons tissm\ nniscle, hone, etc.) is that the specific cells lie in and are sei)arate(l hy a definite stroma, in which hlood and lym|)h \(>ssels may or may not he present. Lepidic and hylic tnmors may be either typical or atypical. The typical blas- temas are slow growing, and their structure approaches that of normal adult tissue; the atypical l)lastomas are composed of rather immature cells, do not closely resemble adult tissue, and grow raj)i(lly. Typical blastomas are more or less encapsulated; the atypical are infiltrating. Typical blastomas are benign, atypical blastomas are malignant. E.xamples of typical (benign) lepidic tumors are papilloma, adenoma; of hylic tumors, are fibroma, osteoma. Examples of atyj)ical (malig- nant) lepidic tumors are epitlwlioma, carcinoma; of atypical hylic tumors are the numerous varieties of sarcoma. In addition to distinct tumors, certain blastomatoid f/rouihs (Adami) must also be recognized; they approach more closely the reacti^■e changes of infianunation, and correspond to the "continuous hypertrophies" or "out- growths" of Paget (1853) as distinguished from the true tumor or "discontinuous hypertroj)hy" of that author. Typical (Benign) Hylic Tumors. — The most important of these are tumors resembling the following normal tissues: Fat (Lipoma); Fibrous Tissue (Fibroma); Cartilage (Chon- droma); and Bone (Osteoma). Although many varieties of tissue may exist in the same tumor, yet one usually is so predomi- nant as to give its name to the growth. If another tissue is present in fairly large amount, a compound term is used, thus fibro- lipoma, the tissue present in greatest abun- dance always being named last. Lipoma. — This may consist rather in an hypertrophy of fat normally present (lipo- matosis, a "continuous hypertrophy or out- growth") than in an actual tumor. Multiple lipomas are not rare (Fig. 54). A lipoma rarely is well encapsulated. It grows slowly, produces no discomfort except from its size or position, and is absolutely benign. The skin over it is not discolored nor adherent, though a slight dimpling may be present oc- casionally, from fibrous bands supporting the tumor between the skin and deep fascia. It is soft, easily movable on the underlying tissues, and semi-fluctuating. A lipoma sometimes Fig. 54. — Lipomatosis aiTecting only the extremi- ties, aged fifty-one years. Began at fourteen years. Father had the same con- dition. Episcopal Hospital. 108 TUMORS will gradually shift its position under the force of gravity. It may occur oil any part of the body, and occasionally in the sub-peritoneal fat or omentum. Its seats of predilection are the limbs, trunk, and neck (Fig. 55). It frequently is fibrous in character, then being firmer than a pure lipoma (Fig. 50). It may be attached })y a j)edicle deep down in a muscular interspace, occasionally to periosteum. ^Mucoid degeneration may occur (my.vo-lipoma) , especially in internal lipomas. Diagnosis may be aided by freezing the growth, whereupon it will become hard. Treatment. — If any treatment is required, excision should be done. Fig. 55. — Lipoma of neck, duration nineteen years. Very soft, almost fluctu- ating. (Not goitre; not attached to larynx; does not rise in swallowing.) Episcopal Hospital. Fig. 56. — Fibro-lipoma of right cheek in a girl, aged fifteen years; growing slowly for last nine years. Sight of left eye lost from smallpox in infancy. Episcopal Hospital. Xanthoma. — Xanthoma is a small flattened benign fatty and fibrous tumor in the skin, whose nature is not well understood. It is named from its yellow color, occurs most frequently around the eyes, and is sometimes seen in persons' with gall-bladder disease. Usually no treatment is required. Fibroma. — Tumors consisting solely of fibrous tissue are rare; they usually are small (Fig. 57), frequently multiple, grow slowly, and are well encapsulated. Depending upon the amount of fibrous tissue present, fibromas are named hard or soft. The latter is the more frequent variety, and is well represented by the mucous polypi growing in the naso-pharynx. The tumor is firm to the touch, pale and glistening on section, with a capsule usually demonstrable. The favorite sites of development are the subcutaneous tissues, along nerve trunks, in periosteum, fascia, the uterus and mammary gland. Some of these must be regarded as fibroid over-growths rather than as distinct tumors, e. g., fibroma molluscum. Fibromas frequently undergo degeneration, FIBROMA 109 Fig. 57. — Fibroma pendulum. Episcopal Hospital. particularly tlir iiiucoid, forming' a tiiinor known as myxoma; tliis is especially t're(|uent in nnicons [)()lyps; a tnnior in or hetween the > di.s-ca.se (p. 719). As already noted, any chronic irritation seems to pre(iisj)ose to the development of carcinoma. Two forms of epithelioma are distinguishable, the superficial, and the deep-seated, of which the last will be described first. m^ ■■■: ?) \*'y^f," ■ ■ '■■'■'. ■- ■■::00::B: Fig. 69. — Early epithelioma of tongue, to show (a) region of origin by down-growth from preexisting epithelium; h b, epithelial pearls; c, small-celled infiltration in sur- rounding tissue. (Petersen.) 1. Deep-seated Epithelioma. — This, the more frequent variety, commences as a downward proliferation of epithelial cells which preserve fairly well the typical appearance of cells of the rete 122 TUMORS Malpighii, a few "prickle" cells frequently being discernible. These cells are very slightly anaplastic: they preserve their functions so far that they still tend to undergo horny changes, this keratosis resulting in the formation of "pearly bodies," which are really cross- sections of plugs in which the central cells have become horny,, and being compressed by those outside, produce a typical lami- nated appearance (Fig. 69). A little round-celled infiltration may be seen around these in- growths, evidences of reaction on the part of the stroma. This form of epithelioma when growing on the skin usually is first noticed by the patient as an induration (hyper-keratosis), commencing frequently in a senile seborrheic patch (p. 622). Or it may develop from a papil- loma (Fig. 70). Soon the centre becomes abraded, crusts, ulcer- ates, and gives thfe growth an umbilicated appearance (Fig. 71). This ulcer spreads; its edges may retain the features of the original nodule, but usually are less firm, ragged, and only moder- ately raised above the base of the ulcer. It occurs especially on the face and hands, the lower lip being a favorite site. The neighboring lymph nodes are invaded early (three to five months), and the progress of the disease is much more rapid than that form about to be de- scribed. The stench from these ulcerated surfaces is some- times frightful, and alarming hemorrhages may occur in the later stages. Occasionally, early in the course of the dis- ease, the ulcer is covered with warty excrescences (Papillary Epithelioma) (Fig. 72), form- ing one variety of Marjolin's ulcer (p. 58) ; but these warty granulations often disappear as ulceration progresses. Diagnosis. — This will be considered more in detail in the chapters devoted to regional surgery. Any chronic ulcer of the skin or adjacent Fig. 70. — Epithelioma of nose; aged sixty- three years; duration one year. (Developing in a papilloma.) Episcopal Hospital P"iG. 71. — Epithi'liomaof hand; aged seventy- eight years; duration one year. Note um- bilicated appearance. Episcopal Hospital. CLASSIFICATION OF TUMORS 123 niiu'ous membranes should be regarded witli siis])i('ion. Epithelioma in leg ulcers, though very umi.sual, is sometimes seen; it is less infre- quent in the heel. J*r()(/it(n>is is good if excision is done early, before lym])li nodes are I)alpably enlarged; later, recurrence is frequent. Treatment. — Early excision, in one mass with the adjacent lymph nodes and all intervening sul)cutaneous tissue, is the only form of treatment which offers hope of perman- ent cure. If an operation is contra- indicated for any good reason, the .r-rays may be applied, and in the very earliest stages the ulcer sometimes heals under their influence; but recurrence is usual, and by dilly-dallying with .r-rays the favorable time for excision may be lost. In some inoperable cases of ex- ternal carcinoma relief may be secured by desiccation with the high frequency current, or by fulguration. The former is suitable only for surface growths, while fulguration is more useful for deeply seated tumors after eurettement or partial extirpation. 2. Superficial Epithelioma (Ro- dent Ulcer, Jacob's Ulcer). — This was first described as a clinical entity by Jacob of Dublin in 1827. It was first recognized as a variety of carcinoma by Warren in 1872. i The epithelial cells which grow down from the skin are extremely atypical, rounded, polygonal, or even spindle-shaped. Because they do not form "epithelial pearls," Krompecher (1903) has named this type of epithelioma "basal-celled carcinoma," on the theory that it is the only type formed from basal cells; but Adami contends that all epitheliomas are so formed, and that whereas in all others the cells develop to the horny stage, in the rodent ulcer the cells are unable to do so because they present a higher degree of anaplasia. The favorite site of rodent ulcer is on the upper half of the face, especially near the ala nasi, on the lower eyelid, or the forehead; it is almost unknown on other parts of the body. It is often preceded by changes in the skin (keratosis,- etc., see p. 622) of an irritative character, and rarely is recognized until a small ulcer has formed, scabbed over, and again become ulcerated several times. The ulcer spreads very slowly, gives little discharge, is painless; has raised, firm, glistening edges; and occasionally heals in one part while extending Fig. 72. — Papillary opithelioma (superficial epithelioma lately show- ing more malignant characteris- tics); aged seventy years; duration five years. Episcopal Hospital. ^ Borst and other pathologists class it as an endothelioma or alveolar sarcoma. 124 TUMORS in another (serpijjinous ulceration). It does not attack the neighbor- ing lymph nodes, and, contrary to what would be expected from its high grade of anaplasia, is in general much less malignant than the deep-seated epithelioma just described; but it destroys, surely if slowly, everything in its course — eating away cartilage, bone, con- tents of the orbit, opening the nasal cavities and sometimes exposing the brain, before death comes. Sometimes, after progressing slowly for many years, the rodent ulcer will suddenly take on rapid growth, and assume the character of a deep-seated epithelioma (Fig. 72). Fig. 73. — Rodent ulcor invading or- bit, in a woman, aged thirty-five years; duration eighteen months. (Dr. W. Walker's case.) Episcopal Hospital. Fig. 74. — Rodent ulcer; duration over five years. Eye destroyed. Had so far only x-ray treatment. Now inoperable. Episcopal Hospital. Diagnosis. — It must be distinguished chiefly from the deep-seated epithelioma. In rodent ulcer the edges are harder, more raised, glistening, and sometimes covered with fine capillaries; the base of the ulcer is flatter and not so deeply placed; secretion is less; growth is much slower; the lymph nodes are not invaded; and microscopical examination of an excised portion will show no pearly bodies, and extremely atypical cells. Prognosis is good with proper treatment sufficiently early. Treatment. — Excision should be done, but it is not necessary to remove the adjacent lymph nodes. Even in advanced cases com- plete excision is seldom followed by recurrence, so that operation should not be refused in any case where reco^'ery from the operation itself seems certain. Very early treatment, by an expert, with radium emanations, frequently causes the ulcer to heal without visible scar; but recurrence is not unknown. The remarks as to .r-ray treatment, made at p. 12.3, apply here. The patient shown in Fig. 74 had been treated for five vears with the .^■-ra^■s before she came to me for GLANDULAR (AliClXOMA 125 surgical a(l\ico; she tlien was a confirmed alcoholic and niorphiiio- maniac, and the tumor was absolutely ino|)ral)le. Glandular Carcinoma. — This is so-called because it grows in glands. Two forms may be recognized, according to the extent that the tumor departs from the typical glandular form: 1. Adknocahcinoma. — The less atypical forms, known as adeno- carcinonui, arc composed of alveolar spaces, lined with cells arranged around their periphery, and rarely piling up on each other so as to encroach on the lumen. This form is therefore known also as colvmnar or ri/lindrical-crlird carcinoma (Fig. To). By obstruction of the ducts and continued secretory action of, or from death and liquefaction of the cells, these aheoli may be converted into cysts {cy.stadeno-car- cinoma). It affects especially the rectum, pylorus and lesser curvature of the stomach, cecum, etc., frequently developing from preexisting ulcers or adenomas; or from polypi, when it is wont to assume a cauliflower-like or fungating api)earance. It occurs also, but more rarely, in the cervix uteri, naso-pharynx, larynx, and gall-bladder; also from cell-rests in the neck (})ranchiogenic carcinoma, p. 683). ^ Fig, 75. — Microscopic appearance of adenocarcinoma (cylindrical-celled carcinoma) of the rectum. (Lexer-Bovan.) 2. Solid-celled Carcinoma. — The most atypical form of gland carcinoma consists of solid j)lugs of epithelial cells, there rarely being any lumen whatever (Fig. 7(3). All grades may exist between this form and that previously described. Two main varieties of the solid-celled carcinoma are recognized, dej)ending upon the amount of stroma present: when this is excessive, the tumor is said to be a "scirrhus" (srlrrlums carclnoina); when the stroma is deficient, and the cellular elements conspicuous, it is called a medullary carcinoma, 126 TUMORS or, from its gross resemblance to the brain on cross-section, "encepha- loid." When stroma and parenchyma are present in equal amount it is described as carcinoma simplex, or "acute scirrhus." Solid-celled carcinoma affects especially the mammary gland and the cervix uteri, though in both situations various combinations of carcinomatous growth may be encountered. Fig. 76. — Microscopic appearance of solid-celled carcinoma, arising in the neck of the uterus. (From "Diseases of Women," Bland-Sutton and Giles.) Gland carcinoma is especially prone to ulceration, the ulcer being deeper than in epithelioma, and there being a much greater tendency to fungosity. Colloid degeneration is not unusual, particularly in carcinomas of the intestinal tract; it is due, according to Adami, to the accumulation within the cells of modified mucin which they cannot excrete, the result being that entire alveoli may be distended with this glistening, translucent material. Symptonts. — The symptoms of gland carcinoma depend so much upon the seat of the tumor, that their description is best postponed to the chapters on regional surgery. Prognosis. — Untreated, or treated only palliati^'ely, the expectation of life in carcinoma has been estimated at eighteen months for the medullary, and two and one-half years for the scirrhous variety; for, although, in the latter, many patients survive three, five, or even ten years, yet an equal number die in less than the average period, men- tioned. The prognosis after operation will be discussed with regional surgery. TRANSITIONAL LE PI DO MAS 127 Treatment. — All operable carcinomas should he excised, at the earliest possible moment, in one mass with the neighboring lymph nodes; when iMoperal)le, palliative treatment consists in dressing the ulcer (of external cancers) with permanganate of potash or other deodorant, and in giving such stimulants, tonics, and anodynes as shall make life endurable. Certain palliative operations are applicable to inoperable internal carcinomas. Transitional Lepidic Tumors. Mesothelioma and Endothelioma. — In addition to the classes of lepidomas already described (derived from epiblast and hypoblast), Adami places in a separate division those tumors derived from mesothelium and endothelium. As these were themselves derived from the mesoblast, and as this in turn was formed partly by epiblast and largely by hypoblast, it is but natural to find that mesothelial and endothelial tumors present at times the characters of lei)idomas (epi-or hypoblast), at others those of hylomas (mesoblast). Therefore they are well named transitional lepidomas, because while they usually resemble ordinary lepidomas, they at times in whole or in certain parts grade so imperceptibly into hylomas that it is impossible to say to which class they really belong. In this group, embryogenetically at least, belong the lepidic tumors of the uterus; as these closely resemble similar tumors of epiblastic (mammary) and hypoblastic (intestinal) origin, Adami supposes that the epiblast has overgrown the primary mesoblast of the genital tract. These tumors, however, frequently appear either sarcomatous {i. e., mesotheliomatous) or endotheliomatous in parts, so it is evident that they possess primary mesoblastic characteristics. While there are typical transitional lepidomas (adenoma), the tumors in this group most important for the surgeon are atypical (carcinomatous) in nature. Adenoma and carcinoma of the prostate are included in this class, as well as rarer tumors of the ureters, seminal vesicles, and vas deferens; similar growths of adrenal, kidney, ovary, and uterus; also mesothelioma of the pleura, etc. For reasons already given, the tumors of the uterus resemble usually ordinary gland carcinoma. The most important surgically of all the mesotheliomas is the malignant growth of the adrenal gland known as hypernephroma. Hypernephroma. — The medulla of the adrenal develops from the nervous system, and its cortex from the mesothelium, closely related to that which forms the cortex of the kidney. The adrenal medulla sel- dom gives origin to a tumor; when it does it forms a ganglioneuroma. The hypernephroma (alveolar sarcoma, angeiosarcoma, perithelioma, carcinoma, etc.) springs from the adrenal cortex, and is, therefore, classed as a mesothelioma. In it may be clearly seen the transitional type from carcinomatous (lepidic) to sarcomatous (hylic) arrange- ment of the alveoli (Fig. 77). Owing to fetal inclusions in ovary or testis, mesotheliomas may occur also in those organs, and more rarely in the kidney itself (Chapter XXV). The ordinary hypernephroma behaves as a malignant tumor, growing sometimes to immense size, invading the kidney, and possessing firm retroperitoneal connections. 128 TUMORS The only treatment is prompt excision, which implies nephrectomy; the operation is difficult and bloody, and recurrence is usual. Bony metastases occur, occasionally only a single metastasis (Scudder, 1910). nbnzi nbnzi: Fig. 77. — Hypernephroma of kidney. Transition from adenomatous to sarcomatous type of growth: nbnz', adenomatous overgrowth of solid columns or masses of cells of adrenal type; nhm", transition to sarcomatous arrangement; K, a kidney tubule involved in the growth. (Debernardi.) Mesothelioma. — Mesothelioma may arise in pleura, peritoneum, or rarely in pericardium or synovial membrane. It appears as a pseudo- inflammatory thickening of the serous membrane, producing a flattened, nodular or fungous tumor, composed of "elongated acini, lined with irregular, swollen cells, . . . resembling the curiously epithelioid type of cells we encounter in some endotheliomas," these acini lying in an abundant fibrous stroma (Adami). I have seen one mesothelioma of the pleura, in a child of three years, not recognized as such by the surgeon, who operated for empyema. Endothelioma. — From this class should be excluded blood and lymph vascular changes not truly blastomatous. All such conditions as nevi, telangiectases, etc., will be discussed under surgery of the vascular system (p. 244). Here we have to do only with typical and atypical neoplasms of endothelial tissues. They are classed as hemangeio- endothelioma and lymphangeio-endothelioma ; surgically they are not of much interest. Briefly, they are formed by concentric, and at times eccentric proliferation of endothelium of blood or lymph capillaries. An atypical hemangeio-endothelioma of the inner surface of the cranial dura mater, in which calcareous deposits have occurred, is called a psammoma. Perithelioma is a tumor in which the lymph cells lining the perivascular lymph spaces proliferate; when hyaline degen- eration occurs in these cells, the tumor is called a ci/lindroma. The growth occurs in the kidney, bones, and skin. Endothelioma occurs oftenest in the skin, in the region of the parotid, in the genital glands, bones, lymph nodes, and dura (Park, 1907). Tumors of the Carotid Body (p. 680) tend to the peritheliomatous type. CYSTS 129 Melanoma.- Tliere is great uiiccrtainty wiR'tlicr tliis tumor belongs among sarcomas or not. Adami is inclined to place it among transi- tional Icjjidomas. It arises by atypical i)r()lifcration of tlic pigment- containing cells {rliroiiKttophorcs) of the rete Maipigliii in tlu; skin, or of similar cells in the uveal tract of the eye. Ordinary pigmented nevi, which are either congenital deformities, or typical as distin- guished from aiy])i('(d melanomas, sometimes become transformed in adult life into this most malignant type of tumor. Bcgimiing in a cutaneous nevus or in the eye, a melanoma gives rapid and wonder- fully widespread metastasis, by both blood and lymph chamicls, to skin, internal organs (especially liver), ])ones, lungs, brain, etc. The only ircdiincnt is wide excision or amputation before metastasis occurs. Cholesteatoma. — Cholesteatoma is a tumor regarded l)y 15orst and others as of endothelial origin; others (Ziegler) think it ectodermic, resembling ordinary dermoid cysts (p. 130). The contents consist of "white, pearl-like, glistening masses, which are concentrically arranged," apparently the remains of compressed and cornified epithelial cells. They occur in the middle ear, pia mater, and urethra. The}' vary in size from a cherry seed to a hen's egg. They may cause pressure symptoms in the cranium, or otitis media when in the middle ear (Lexer). Excision is the best treatment. CYSTS. A cyst is an abnormal but encapsulated collection of fluid, in a cavity which is not provided with any outlet. The fluidity of the contents varies from liquid to semi-solid. One cavity (unilocular) or many (multilocular) may exist. A cyst is to be distinguished from an abscess, which is not strictly encapsulated; from dilatations (ectasia) of normal channels (varix, aneurysm) which still have an outlet; from effusions or transudations into preformed and normal cavities, which are classed apart (hydrops articuli, hydrocele, hygroma, hydrothorax, hydrocephalus, etc.) — though such collections may be encysted; and from cystomas, which is a term sometimes used to describe neoplasms in which cysts form incidentally (p. 119); but a distinction cannot always be made clinically between cysts and cystomas. Cysts may be classed as Extravasation, Retention, and Parasitic Cysts. All cysts tend to become spherical or oval unless compressed by neighboring parts. Extravasation Cysts. — These are encapsulated collections of fluid not in a preexisting cavity. An example is the hematoma, due to extravasation of blood, which as the result of reaction and condensa- tion in the surrounding structures, becomes in time encapsulated. Certain bursal tumors (p. 281) may belong in this class. Extravasa- tion of lymph, forming a chylous cyst, is very rare (p. 268). Extra- vasation of urine rarely forms a distinct cyst. Retention Cysts. — Retention cysts arise in preexisting cavities. They form the largest and most important class, and may arise either 9 130 TUMORS because there is no opening to the cavity, or because the normal opening is obstructed. In either case it is evident that secretion or transudation into the cyst must be more rapid than absorption. Generally speaking, these cysts may be classed as post-natal or antenatal in origin. I. Of Post-natal Origin. — Examples of cysts due to obstruction of ducts are Raiuila, Cysfs of Bartholin's Gland, Galadocele, Sebaceous Cysts, Hydronephrosis, Hydrops Vesicce Fellece, etc. Examples of cysts formed in cavities normally having no outlet are corpora lutea and iollicular cysts of the ovary, cystic goitre, etc. Fig. 78. — Sequestration cyst, or dermoid (congenital at:)normality) of scrotal raphe. Episcopal Hospital. Sequestration Cysts deserve separate mention. They are due to the sequestration and detachment of portions of the true skin either (1) during ante-natal development, when they are congenital, and occur along the fissural lines of the body; or (2) are caused in post- natal life by implantation of portions of the true skin by trauma. Most dermoids belong to the former class (Fig. 78), though some, especially pilo-nidal cysts, are occasionally of post-natal development. Implantation dermoids are seen in the fingers of sewing women, or in the faces of shavers. I have several times excised from the face cysts supposed to be wens, which on opening were found to contain two or three long hairs growing from the interior of the c yst wall, which in such cases is lined with squamous epithelium, not with secreting cells. II. Of Ante-natal Origin. — These may be considered in three divisions : 1. Cysts Due to Persistence of Parts of Embryonic Ducts. — Thyro- glossal, Branchial, Vitello-intestinal, and Urachal Cysts: the "Tubular Cvsts" of Bland-Sutton. GENERAL REMARKS ON EXCISION OF TUMORS 131 2. Cysts of Geniio-urinary Passages: (a) In the Male. — Encysted liydrocele of testis, probably due to per- sistence of the cmbrj'onic vasa ett'erentia. (6) In the Female. — From various tubules composing the parova- rium, and perhaps from the paroophoron. 3. Congenital Cysts of Glandular Organs. — The liver and kidney are especially affected. The pathology is obscure. Parasitic Cysts. — In man, two main varieties of parasitic cysts are found, those due to Trichina Spiralis and Tenia Echinococcus. The trichina, much rarer, forms very small cysts, oftenest in muscles (p. 27()). The echinococcus, commonly known as hydatid cysts, may attain an immense size. This parasite is an inhabitant of the intes- tinal tract of dogs, and the ova may gain entrance to the digestive tracts of those who have to do with dogs and whose habits are not very cleanly. It is a rather rare disease in this country. The shell of the ovum is dissolved by the patient's intestinal juice, and the larva, thus liberated, works its way through the intestinal mucosa usually into a branch of the portal vein, and thus reaches the liver; here it proliferates, and one large, or innumerable small, conglomerate cyst will be found depending upon the stage of development. They are easily recognized by the "booklets" they contain. The lungs, brain, and other parts of the body may also be affected. Treatment is discussed in Chapter XXIV. Fig. 79. Elliptical incision for the Fig. 80. — Double S, which meant the hands and forearms up to and including the elbows.) The hands are best prepared by washing in hot soapsuds, with careful use of a nail-brush, for ten minutes; then the soap is rinsed off, and further removed by soaking the hands and forearms in alcohol; finally they are soaked in a hot solution of bichloride of mercury (1 to 2000) or of carbolic acid (2.5 per cent.). The patient's skin is prepared in the same way, and is covered with sterile gauze until the time of operation. The mechanical cleansing with the nail-brush, aided by the macerating efi'ect of heat, and soapsuds, removes all loose epithelium and probably removes almost all the germs present. The alcohol by its dehydrating effects opens up the orifices of the cutaneous glands and allows the antiseptic subsequently used to penetrate the skin more effectively, thus weakening, if not killing, the germs always present in the deeper layers. IVIost surgeons in this country prefer to 1 It is worth noting in this place that all antiseptic solutions are much more efficient when hot than if cold or merely luke-warm. AX T J SEPSIS AND ASEI'SIS 141 wear ()\tT tlit'ir hands tliiii ruhhcr gloves wliicli have been properly sterili/.fd. Tliere is no douht to my iiiiiid that they are a most val- uable addition to the surj^ical armamentarium, chiefly as a jirotection to the sur<:;et)n from contamination in septic cases. The use of fi;love.s in no way absolves the surj>;eon from careful ])rei)aration of his hands, l)ut it enables him in emeru'cncy to pass from a septic tt) an aseptic oi)eration with an imi)unity which can never be enjoyed when he operates with bare hands. All ])ersons concerned in the operation wear sterile gowns, and caps, and the operators wear face masks of gauze to ])revent contamination of the wound or the instruments or dressings in any concei\"able manner. lodin Disinfection. — (irossich in 1908 found if the patient's skin (without previous preparation except dry shaving) were painted with a 10 to 12 per cent, alcoholic solution of iodin shortly before operation, at the time of operation, and at the close of the operation, the woimds healed better than after the habitual methods of skin prej)aration. This method is poi)ular for its simplicity and efficiency, and is now in general use. ]\Iost surgeons find an alcoholic solution of from 3 to 5 per cent, strong enough, but many do not sufficiently appreciate the fact that the skin must be dry, if the iodin is to be of any use. It must not have l)een wet for three or four hours at least. Antiseptic methods of operating wTre introduced before aseptic methods (Lister, 18G5; Lucas-Championniere, 1869, 1876), and are still most widely applicable. Here, after preparing the dressings, instruments, and skin as above, the surgeon keeps his instruments in antiseptic solutions (2.5 per cent, carbolic acid); uses sponges soaked in antiseptics for mopping out the wound; and at the conclusion of the operation applies a stronger antiseptic solution (5 per cent, carbolic acid, 5 or 10 per cent, zinc chloride, 1 to 1000 corrosive sublimate, etc.) to the entire surface of the wound. In this way he makes sure that any microorganisms introduced into the w^ound, accidentally, will have an unfavorable soil for growth, and that in all probability they will be so weakened by the antiseptics employed as easily to be killed by the tissues of the body. This method of operating is applicable to all primarily septic conditions (compound fractures, necrosis, abscesses, malignant tumors, most amputations, etc.), and is valuable in a somewhat modified form in all operations where the tissues are much })ruised or long exposed to the atmosphere during the course of the operation (some excisions, ununited fractures, tedious dissec- tions, etc.). When, however, the operation is of short duration (under half an hour), or when the tissues, even during a longer operation, are not bruised or otherwise unduly injured, and especially in visceral surgery, the aseptic method is superior. Aseptic methods of operation have been in general use only for the last ten or fifteen years, and were systematized largely by Terrier and his pupils. The instruments, dressings, etc., are sterilized, and the instruments are placed in sterile water or laid on a table covered with sterile sheets. The hands and the patient's skin are prepared in the 142 SURGICAL TECHNIQUE usual way, but no antiseptics whatever are used during the course of the operation; everything coming into contact with the wound is sterile; and it depends on the unceasing and seemingly pedantic pre- cautions of the surgeon to keej) the wound aseptic. If one mis-step is made, the aseptic has to be abandoned for the antiseptic method; and while I think the surgeon should always employ the aseptic method when he safely can, because antiseptics are at times harmful to the patient, and occasionally delay the process of repair, yet it cannot be denied that adherence to a strictly aseptic technique is much more difficult; and it must be acknowledged that many surgeons seem incap- able of practising it thoroughly. When either method is properly employed, the wound heals without noticeable inflammatory reaction, no stitch abscesses form, no discharging sinuses remain, no ligatures are slowly eliminated from its depths, no granulations persist at one end of the incision, the comfort of the patient is enhanced, and the after-treatment much simplified. MINOR SURGERY. Counter-irritation. — Counter-irritation is conveniently secured by the use of very hot compresses, by turpentine stupes, or by means of plasters of mustard, capsicum, etc. While these remedies are merely rubefacient in their effect, cantharides plaster will produce a blister (vesication); the surface of the plaster should be wiped with olive oil or petrolatum, so as to prevent it sticking to the cuticle. It should be removed in six or eight hours, and the blister will com- monly draw for several hours more; meanwhile it should be dressed lightly with an ointment, and when fully drawn the tense cuticle should be punctured with an aseptic bistoury, and allowed to collapse on to the face of the blister as the serum exudes. When the blister shows a tendency to dry up, this may be encouraged by applying talc or other dusting powder. Canterization is readily secured by means of the Paquelin cautery, in which the platinum cautery point is first brought to a red heat in an alcohol flame, and is then kept incandescent by exposing it to the vapor of benzole or rhigolene, which is pumped along the hollow handle of the cautery iron, from the receptacle w^here it is contained, by means of a hand bulb. To produce vesication or still slighter degrees of counter-irritation, it is sufficient merely to touch the skin with the cautery iron when at a cherry red heat, or even to hold it close to the skin without bringing the iron into actual contact w^ith it. In certain operations the actual cautery is of the utmost value in checking the oozing of blood or destroying the fungous granulations of inoperable tumors. The wound left is rendered aseptic by the heat, and will usually heal without suppuration. Whenever using the actual cautery, the highly inflammable quality of ether must be remembered. Acupuncture. — Acupuncture is a little operation sometimes used in cases of lumbago, etc. After preparing the patient's skin as for an MINOR SURGERY 143 operation, six to ten sterile needles (ordinary hat pins will do) are tlirust intt) the k)ins with a quiek })oring motion, and are allowed to remain in i)laee a few minntes. Care, of course, must be exercised not to injure any superficial vein, nerve, etc., and not to enter the spinal canal. No anesthetic is required. Vaccination. — Vaccination, though usually done by the family I)hysi(i;in, is a surgical procedure. The method I prefer is the follow- ing :'the skin of the arm is rubbed briskly with an alcohol sponge, and vigorously dried with sterile gauze; this arouses the circulation of the part, and makes the virus more apt to " take." Then with the belly of an asej)tic and rather dull scalpel the cuticle is scraped ofl' over an area about s inch (1 cm.) square until the surface is moist. No blood should be drawn. The vaccine is then quickly applied, and rubbed into the abraded area by means of the ivory point or glass tube in which it is supplied. The vaccinated area is allowed to dry, conqjletely , in the air, and no shield or bandage is em])loyed. In a continuous series of several hundred vaccinations by this method, when house surgeon at the Episcopal Hospital, I failed to secure a "take" at the first attempt, in only two or three previously un^■accinated patients. The wound should be painted daily with a 8 per cent, solution of iodin. Hypodermic Injections. — Convenient tablets containing the requi- site amount of the drug are easily obtained from manufacturers. The tablet is dissolved in a half dram of sterile water or saline solu- tion, or the water with the tal)let in it may be sterilized in a spoon over a flame. The fluid is then drawn up into the barrel of the hypo- dermic syringe previously sterilized by boiling or by soaking in an antiseptic solution (which should of course have been removed by rinsing the interior of the syringe in sterile water). The sterilized hollow needle is then screwed on to the nozzle of the syringe, and any bubbles of air are expelled by driving the piston home, while the needle is held upward, until the fluid spurts. Then a fold of the patient's skin, prepared by vigorous rubbing with an alcohol sponge, is picked up between the thumb and finger of the left hand, and the needle quickly thrust obliquely into this fold, so that the point enters the subcutaneous tissues. Care must be taken to avoid entering a subcutaneous vein, wounding a nerve, etc. The best situations for hypodermic injections are over the deltoid muscle, on the outer surface of the thigh or calf, in the buttocks, the loins, or the lateral abdominal wall. No dressing is required for the needle puncture. Use of Saline Solution. — The object of this solution is to supply a fluid as nearly like the blood as possible. The following formula is recommended by Park: I^ — Calcium chloride, 2 parts Potassium chloride, 3 parts Sodium chloride, 9 parts Sterile water, 1000 parts This should be prepared aseptically and should again be sterilized before use. In emergencies it is sufficient to add a teaspoonful of 144 SURGICAL TECHNIQUE sodium chloride (table salt) to each pint of water, boiling the solution before using. This fluid is used hypodermically (hypodermoclysis), by the bowel {yrodoclysis) , and by intravenous infusion. It is also widely employed, especially in abdominal surgery, as a substitute for sterile water. It should be injected at a temperature of from 110° to 115° F. For hypodermoclysis, proctoclysis, or intravenous use, it is convenient to let it flow out of a glass jar graduated from above downward, so that a glance will show how much has been given. In emergencies, a sterile fountain syringe or funnel will answer the purpose. The main purposes for which it is used are to combat hem- orrhage and shock by restoring blood pressure (p. 175), and to dilute toxins circulating in the blood. Hypodermoclysis.^ — This is the subcutaneous instillation of saline solution. A long hollow needle, with large calibre, is used ; it is attached to a rubber tube connecting with the receptacle, which may be several feet higher than the patient. The clip on the tube is released, and, while the fluid is running from the needle, this is thrust into the sub- cutaneous tissues as in administering a hypodermic injection. The best sites for hypodermoclysis are under the mammary glands, over the lower border of the pectoralis major; in the flanks, the lateral abdominal walls, or between the scapulae. From eight to ten ounces may be introduced through one puncture, the accumulating fluid being gently rubbed out into the tissues. Rarely more than one quart is required by hypodermoclysis. The fluid is not absorbed very rapidly, and where immediate effect is desired it should be given intravenously. The needle punctures should be painted with collo- dion and sealed with a scab of absorbent cotton. Under the term axillary infusion has been described a method of hypodermoclysis by which absorption is very rapid: a puncture is made, with a bistoury, through the skin over the pectoralis major muscle about midway between the clavicle and anterior axillary fold; then, with the fingers of the left hand in the armpit as a guide, the hypodermoclysis needle (not dangerous because blunt) is thrust through this puncture into the cellular tissues of the axilla, traversing the pectoral muscle; the solution is then allowed to flow. Proctoclysis. — Proctoclysis, the rectal instillation of saline solution,^ is widely employed in the treatment of peritonitis (Murphy, 1905). A soft rubber catheter is attached to the rubber tube leading from the reservoir, which should not be more than a few inches higher than the patient's buttocks; the eye of the catheter is placed just within the anus. The solution should flow into the rectum very slowly, about a pint and a half every forty to sixty minutes for an adult. If a pint and a half of the solution are placed in the reservoir every two hours, eighteen pints will be absorbed in a day, and the rectum will have periods of rest of an hour or more after each amount has been absorbed. The catheter is to remain in place continuously. This treatment, may 1 Sterile water, without the addition of salines, is just as efficient; it is not irritating to the bowel and is absorbed as readily (Trout, 1912). MIXOli SURIJEHY 145 1)0 coiitiiiiKMl Tor four or five days if necessary. If too inueli fluid is administered, slight edema of the ankles, hands, and even face may appear (Murphy). The sohition is j)hieed in the container hot (105° to 110° F.), and may he kept hot by hot water hags (Fig. 805); but it is probable that owing to its slow flow, it is about the temperature of the blood or lower after traversing the tube to the ])atient. Intravenous Infusion. The patient often is so shocked that no anesthetic is required. A blunt pointed cannula is used, the eye being bevelled to facilitate its introduction into the vein. Select a super- ficial vein (usually the median cephalic at the elbow), and tie a tight bandage around the extremity on the cardiac side of the vein selected, in order to render it visible and fully disteniled. Prepare the skin and your hands in the usual way. Then make an incision somewhat obli(|uely to the course of the vein, about an inch long, and cut down with light strokes directly on to the vein, which may be embedded in fat. Do not tease and maul the fat; this favors infection of any wound. When the vein is thoroughly exposed in this way, thrust a grooved director across beneath the vein, and along the groove slip two ligatures. Draw one of the ligatures to the distal side of the grooved director and ligate the vein; draw the other ligature upward, on the cardiac side of the director, and loop it but do not tie it tight. Then pass a sharp scissors along the grooved director, and, controlling the blood by a finger of the other hand on the cardiac side of the director, cut the vein half way across (Fig. 96). Lay aside the scissors, and take the infusion cannula in the right hand, have the clip removed from the tube, and, while the saline solution is running from the cannula, gently insert this into the gaping wound in the vein, point- ing it toward the heart, and tie the ligature already placed so as to secure the cannula in the vein. Then withdraw the grooved director and have the bandage around the limb cut, so as to allow the venous current to flow. The reservoir should not be held more than a foot or two above the patient's body, and the saline sohition should not flow more rapidly than a pint in ten minutes. The amount introduced must depend on the state of the patient's pulse. Usually a quart is more than enough: occasionally several quarts will be required. Direct Transfusion. — This operation, introduced by Crile (1906), implies the transference of blood directly from an artery of a healthy person (known as the donor) to a vein of the patient (the recipient). It has entirely superseded indirect transfusion, a method in which blood was first drawn into a receptacle, then defibrinated, and finally injected into the patient's veins. For the operation of direct trans- fusion local anesthesia (cocain) should be used. Crile's technique requires few special instruments beyond the silver cannula (Fig. 97) ; hyi)odermic syringes and 0.1 per cent, cocain solution (Formula A, p. 156); scalpel, scissors, two rubber-covered artery clamps (Nunneley's clips do very well), six fine bladed ("mosquito") hemostats, linen or silk ligatures; as well as needles and suture material for closing the skin wound. 10 146 SURGICAL TECHNIQUE Give })oth donor and patient a hypodermic injection of morphin half an hour before the operation. Place the donor horizontally on an operating table so arranged that its head may be lowered if the Fig. 96. — Intravenous infusion of saline solution. donor faints. Place the recipient on another table with his head toward the donor's feet. Use cocain locally (0.1 per cent, solntion). Expose first 3 cm. of the radial artery of donor, ligate distal and clamp proximal end. Divide close to the ligature. By squeezing with Fig. 97. — Direct transfusion of blood by moans of Crile's cannula. In the upper illustration the vein is being drawn through the cannula by a sharp hook. In the lower, the end of the vein has been everted and tied to the cannula, and the arterj^ is about to be drawn over the vein. fingers on the free (proximal) end of the artery, the adventitia is made to project beyond the inner coats, and is cut off with scissors. As the adventitia retracts, the muscular and endothelial coats are left MINOR SURGERY 147 projcctinj;. Cover tlie artery with gauze wet in liot saline solution. Expose W to 4 cm. of a large superficial vein of the recipient, ligate the distal and damp the proximal end; divide close to the ligature, and remove the adventitia as above described. Pass the vein through the cannula, which is held by a hemostat; I have found it easier to draw it through with a fine hook (Fig. 97). P^vert the walls of the vein by aid of mosquito hemostats, and ligate with linen or silk the everted vein in the groove next the handle of the cannula. Then with the aid of three mosquito hemostats, draw the artery over the end of the vein, and ligate it around the other groove in the cannula. Unclamp the vein; then unclamp the artery, and let the blood flow slowly. The amount to be transfused depends on the reaction of both donor and recipient. It is best to stop the flow so soon as the donor begins to sigh, indicating respiratory embarrassment from the loss of blood. Of course, if the recipient is brought to a satisfactory state by a less amount of blood, less will suffice. It is truly astonishing to see the color return to blanched lips, the lustre to the eyes, and to behold the general hienseance which is produced by direct transfusion.^ Phlebotomy. — Phlebotomy which is usually preferred to arteriotomy for "letting blood," is generally done in the median cephalic or median basilic vein. The vein is made tense by applying a tight bandage above it, the skin is properly prepared, and a small incision (1 cm.) is made directly over and into the vein. No anesthetic is required. The spurting blood is caught in a suitable basin; it may be made to run more freely by having the arm dependent or by directing the patient to work his fingers around a bar, alternately tightening and loosening his grip. The patient should be in a sitting posture, so that any faintness may be quickly perceived. It is seldom desirable to draw more than a pint. The wound is dressed with a pledget of sterile gauze, no suture being required; and the same wound may easily be reopened for further bleeding during the next few^ days. Leeching. — The Swedish leech, which is preferred, draws from three to four drams of blood. The skin is carefully washed, and the leech applied over the part to be leeched, but not directly over a super- ficial vein. If the leech does not bite, a little milk or blood should be placed on the skin. When he has drunk his fill he will fall oft"; or this may be hastened by applying salt over the leech and neighboring skin. The blood usually continues to flow for some time, so that a much larger quantity may be drawn from one leech bite than the capacity of the leech. When enough has been drawn, the bite should be dressed antiseptically, and moderate pressure applied. Aspiration. — By means of a vacuum bottle it is easy to withdraw fluid collections through a hollow needle. The bottle is first emptied of^air as far as possible by the suction pump; the valves are then turned, ' Several types of tubes (glass or metal, to be lined with paraffin before using) are now on the market, by which it is thought the operation of direct transfusion is rendered easier than by Crile's original technique; but I have had no personal experience with them. Those of Brewer and of Bernheim are most popular. 148 SURGICAL TECHNIQUE and, the skin having been j)roperly ])repare(l, the sterile trocar and cannula are thrust through the overlying tissues into the collection of fluid (hydrothorax, empyema, cold abscess, etc.)- The trocar is then withdrawn, the valve turned to close its passage, and the valve leading from the cannula to the bottle is opened, allowing the fluid to flow (Fig. 98). If the lumen of the cannula is blocked by flakes of lymph, a stylet may be passed through it from time to time. The puncture sliould 1 c dressed antiseptically. Fig. 98. — Asjiiration of a luml>Mi isrn],a] Hospital ANESTHESIA AND ANESTHETICS. Certain gases, which are respirable, induce unconsciousness when absorbed through the lungs and carried to the nerve centres. The state so produced is called general anesthesia. In addition to uncon- sciousness, which implies analgesia and anesthesia, muscular relaxa- tion is also produced.^ It is possible to secure the same effects from some such drugs when administered otherwise than by inhalation, as by rectal administration; but, as a rule, general anesthesia is secured by inhalation of the vapor of ether, chloroform, ethyl chloride, etc. Local anesthesia is produced by the local use of some drug, usually introduced by hypodermic injection, which acts on the peripheral ner^'es; cocain and eucain are most used for this purpose. General Anesthesia. — The patient should have his bowels well opened the day previously, and should have eaten no food for at least eight hours befor the anesthetic is administered, as all general anes- thetics, especially ether, produce some degree of nausea. In opera- tions not involving the stomach or intestines, there is no objection to the patient drinking a glass of hot water half an hour before the operation. This prevents gastric irritation from any of the anesthetic unavoidably swallowed. Before taking an anesthetic, a thorough 1 Crile has pointed out that general anesthesia secured in the usual way does not prevent nocuous impulses from the seat of opeiation reaching the brain along afferent nerves. If, however, the usual methods adopted to secure local anesthesia are added to the general anesthetic these nocuous associations are avoided. To this principle of operative surgery he has given the name Anoci-association. ^AXESTinCSIA AM) AXK.STU KTICS 149 physical cxainiiiiitioii of tlir lu'iirt and Iiiti^'s should hv made, and the l)atieiit should reino\e false teeth, ehe\viii• drop, such com- ])Hcations are not to l)e feared. Moreoxcr, it is Ixtter for a patient to he nauseated and to ha\'e hronchial irritation after reeo\ery from etlier than for liini to he killed hy chloroform or ethyl chloride. In cases where bronchitis, phthisis, etc., exist, or where the kidneys are seriously diseased, and where some general anesthetic has to be employed, nitrous oxide and oxygen should be ])referred. Chloroform is particularly to be avoided in cases of heart lesion not properly compensated, and in cases of shock. Nitrous oxide causes cyanosis, stertor, and muscular regidity, with such increase of blood pressure that it is esj)ecially contraindicated in patients with arteriosclerosis; its successful administration requires much more skill and experience than does that of ether, but when skilful assistance is available, and the operation will not consume more than thirty or forty minutes, it is when combined with oxygen a safer and more desirable anesthetic than is ether for patients with visceral lesions other than those of the vascular system. Administration of General Anesthetic for Special Operations. — Head AND Neck. — It is found often in operations on the head and neck that the anesthetist is very much in the way, and that the progress of the operation interferes with the proper administration of the anesthetic. One of the simplest methods of o\ercoming this is to have the ether vapor conducted to the patient's mouth through a tube, so that the anesthetist may stand at some distance. This is accomplished by standing the ether bottle in a pan of warm water, to increase the rapidity of vaporization. Through the cork of the ether bottle pass two tubes — an afferent tube which is connected with a hand bulb, and an efferent tube Avhich is three or four feet long and leads to the patient's mouth. If a hooked metal tube is attached at the mouth end, it will hang in the angle of the mouth and keep its place without difficulty. The ether vapor has never caused, in my experience, any evidence of stomatitis. If its irritating effects are feared, the vapor may be conducted by tube over or through a bottle of water before entering the mouth. The patient is first anesthetized in the usual way, and when thoroughly relaxed, the gauze is removed from the face, the mouth tube introduced, and the ether vapor forced into the mouth by use of the hand bulb. Crile's plan is another convenient method. After the patient is anesthetized, the surgeon passes a well greased tube through each nostril to the naso-pharynx, and packs the mouth loosely with gauze. The outer ends of the nasal tube are connected by a Y-shaped glass tube to a long rubber tube, at the far end of which is a funnel lightly filled with gauze. The ether is then administered by being dropped on the gauze in the funnel. It is well to ha^'e a U-tube inserted somewhere in the tube which conducts the ether vapor to the patient, so that in it may collect any condensation from the ether vapor. IxTRATHORACic Operatioxs. — When the pleura is opened, the lung partially collapses, and in consequence there may be considerable 154 SURGICAL TECHNIQUE respiratory nx into the trachea. This is facilitated by the use of a broncho- sc-opic tube or speculum. When the intratracheal tube is momentarily arrestefl at the bifurcation of the trachea, it is withdrawn a})out an inch. If the tube is in correct position air will enter both lungs; if it has been pushed in so far as to be arrested at the division of the right bronchus no air will enter or leave the left lung. ^Yhen in ])roj)er posi- tion, the tube is clamped just outside the dental margin by a frame supported on the ears, resembling a spectacle frame. "The tul)e is now connected with the air pressure apparatus, and air is blown through at a pressure of 10 mm. of mercury. After several minutes, the pressure is raised to 20 mm. and the operation can be begun. When the pressure of the inflowing air and ether equals 20 mm. of mercury, inspiration and expiration will continue, air being inhaled and exhalkl by the side of the tube. If there existed a profuse secre- tion of mucus in the pharynx and trachea, this will be found to have ceased soon after the insufflation was begun. Every two to three minutes, an assistant opens a vent so that the current of air which enters the tube is interrupted for a moment." (Elsberg.) Xo ill eft'ects have been noted from anesthesia maintained by this method. F'ar from favoring pulmonary complications, it seems to prevent them. Local Anesthesia may be secured by freezing the skin with a mix- ture of ice and salt, or by a spray of ethyl chloride or rhigolene. The skin becomes white, covered with minute crystals of ice, and is rendered very tough. The anesthesia lasts only a few seconds, but sufficiently long for opening superficial abscesses, etc. If the patient only knew that freezing hurts as much or more than a sudden stab with a sharp bistoury, he probably would prefer to have this form of local anes- thesia abandoned. Coeain and eiicain are the chief agents used for local anesthesia. Solutions of coeain are unstable chemically, and are destroyed by repeated boiling; in emergency, boiling for a few minutes does not impair their value. Eucain {eucain B) is not so toxic as coeain, is not destroyed by boiling, and is quite as efficient; but the duration of anesthesia is shorter than that produced by coeain. In general, eucain is to be preferred. The addition of saline solution, to make the solution isotonic with the blood, and of adrenalin to constringe the capillaries, thus preventing diffusion of the anesthetic and local 156 SURGICAL TEmXIQUE edema, renders the use of local anesthesia much more satisfac- tory. The apphcation of an Esmarch band above the seat of operation also prevents diffusion of the anesthetic. Cocain tablets which can be sterilized by dry heat, are now on the market. Mitchell (190Sj recommends that each tablet be sterilized in a glass flask as needed, being added to the sterile saline solution just beff>re it is to be used. Finally, the adrenalin solution is to be added drop by drop to the required amount. He gives the following formulae from Braun: A. Cocain hydrochlorate, 0.1 grm. (1.5 grain) Physiologica] salt solution, 100 c.c. (jTT per cent.t Adrenalin (1 to 1000) 5 drops. B. Cocain hydrochlorate, 0.05 grm. (0.75 grain) Physiological salt solution 5 -cc. (tV per cent.) Adrenalin (1 to 1000) 10 drops. Formula A represents a 1 to 1000 cocain solution, anrl may be further diluted with saline solution if large amounts are to be used, as in long operations by Schleich's infiltration anesthesia; while Formula B (a 1 per cent, solution of cocain) is used for operations requiring only one or two h^•podermic injections, when the whole amount of the formula may be employed safely. For applications to mucous membranes (eye, throat, urethra, bladder;, a 2 per cent, solution may be used, and sometimes a 4 per cent, solution. It is dropped on the surface of the eye, and is applied to the nose and throat by a pledget of absorbent cotton: while it is injected into the urethra and bladder by means of the urethral syringe, catheter, or in.>tillator. Hypodermic Use. — The skin is pinched up as in giving a hypodermic injection, but the needle, which enters at one end of the proposed incision, with its point directed toward the other end, is not passed into the subcutaneous tissues, but its point is arrested in the true skin, the first injection being endodermic, not hypodermic. As the piston of the syringe is pushed down, a distinct wheal is raised in the skin; the needle is then pushed on within the true skin until its point reaches the limit of the wheal, when another wheal is pro- duced, and so on until the entire length of the needle has entered. It is then withdrawn and reintroduced at the furthest point reached, and the process is repeated until the line of the entire incision has been anesthetized. An incision may then be made through the skin, and, with a few added drops here and there as required, this degree of anesthesia will suffice for circumcision, removal of sebaceous cysts and small tumors, opening cold abscesses, etc. For such cases Formula B may be used. When a more extensive operation is imdertaken, as one for hernia, goitre, etc., it is best to use the weaker solution (dilu- tions of Formula A), and special attention must be paid to nerves, bloodvessels, and connective tissue bundles (infiltration anesthesia). Almost any quantity of the weaker solutions may be used, especially ANESTHESIA AM) ANESTHETICS 157 when local aiu'stlicsiji is aided by constriction of the linih al)o\'e the seat of operation. Nerve hloek'uuj may he acconij)lishe(l l)y perineural or endoneural injections, the latter being preferable as more accurate and permitting a wider range of o])erative procedure. Certain nerves (ulnar, jjer- oneal) may be reached directly, but usually it is necessary to bare the ner\e by the hypodermic use of cocain as already described. In the endoneural method ((Vile, Pushing, IMatas), the cocain is injected directly among the nerve fibres of the main trunks conveying sensa- tion from the region to })e operated on. Comjjlete anesthesia follows, and as no sensory impulses can reach the nerve centres surgical shock is nuich diminished or totally prevented, a fact which is of value in many amputations. I generally employ 2 per cent, solutions for this purpose. Fig. 102. — vSpinal analgesia. Needle between spines of second and third lumbar vertebrae. Posterior superior iliac spines marked with iodin. Episcopal Hospital. Spinal anesthesia is closely allied to nerve blocking. It was sug- gested in 1885 by Leonard Corning, of New York; was employed in 1889 by Tuffier; and has been more widely used abroad than in this country. The anesthetic acts on the roots of the spinal nerves, not on the cord itself. The injection is made usually in the second or third lumbar interspace (Fig. 102); as a rule, anesthesia (which aflFects both motor and sensory impulses, especially the latter) extends only to the region of the waist, and therefore operations best suited for spinal anesthesia are those on the lower extremities or pelvis. Stovain (4 per cent, solution) usually is preferred to other anesthetics, and is that which I am myself accustomed to use. About 1.5 to 2 c.c. are employed. The anesthesia begins in a few minutes and lasts nearly an hour. As positive contraindications to spinal anesthesia may be mentioned: advanced cachexia, bilateral nephritis with scanty excre- tion, myocarditis, pericarditis with effusion, non-compensated cardiac disease. ]\Iany operations in which spinal anesthesia may seem desirable can be done equally well under local anesthesia ; but for rectal operations and prostatectomy spinal anesthesia is to be preferred, if a general anesthetic cannot be employed. 158 SURGICAL TECHNIQUE Vein anesthesia is a term used to describe a method employed by Bier (1908). He has used it in 134 operations. It is appHcable to any operation on the extremities. He first renders the part bloodless by Esmarch's method (p. 433), and cuts off the general circulation by broad elastic bands above and below the seat of operation; exposing then a superficial vein, he injects into the vein 40 to 80 c.c. of a 0.5 per cent, solution of novocain in saline solution; the solution diffuses through the capillaries of the area sequestrated from the general circulation, rendering every subsequent manipulation painless. At the conclusion of the operation the anesthetic solution may be removed by washing out the veins with saline solution, but this is not always necessary, as most of the novocain escapes into the wound through the capillaries dividt d during the operation. CHAPTER VI. INJURIES AND THEIR EFEECTS. LOCAL EFFECTS OF INJURIES. The local effects of injury depeiid on the part injured, as well as on the force exerted by, and the manner of action of the vulneratins, etc.), may pass uni)ercei\ed at first. In ordinary practice punctured wounds are produced most often by needles, nails, hat pins, splinters, umbrella tii)s, etc. If a needle remains in place, with part of the shaft projecting from the wound, it should be extracted, and unless known to be serioush' infected, Figs. 121 and 122. — Skiagraphs to localize needle in palm of hand. it is sufficient to cleanse the surrounding skin and apply an aseptic dressing. In a patient at the Episcopal Hospital a hat pin which punctured the chest produced no symptoms of any kind, though from the depth and direction of the wound it is certain that the liver, diaphragm, and lung were all traversed. If the point has broken off and is completely buried in the tissues, an immediate attempt to extract it should be made if its position can be detected by palpation; if no clue as to its location exists attempt at extraction should not be made until it has been accurately located by the use of the .r-rays, two exposures in planes at right angles to each other being made (Figs. 121 and 122). The incision, for which local anesthesia some- times is sufficient, should be made obliquely to the course of the needle, being thus more apt to strike it than if made parallel. A 170 INJURIES AND THEIR EFFECTS needle buried in the palm is best exposed by turin'nfi; uj^ a flap of skin. If a large joint has been punctured, the part should be immo- l)ilized, the patient being kept in bed if necessary. In wounds from splinters and rusty nails the danger of tetanus developing is greater; accordingly the ])uncture should be slit up, to ensure the removal of all parts of the splinter, and to allow the application of antiseptics to all parts of the wound. Stab wounds occasionally are seen in cWW practice; they partake of the nature of both incised and punctured wounds, and like the latter are of interest chiefly from the implication of joints, internal organs, bloodvessels, nerves, etc. Their treatment is considered in the chapter dealing with the surgery of these structures. Bayonet wounds are seldom seen nowadays, even in military surgery. In battles with Indians and other uncivilized tribes arrow wounds are sometimes encountered. The arrow-head is very easily detached from the shaft, and reckless attempts to extract the weapon frequently result in the head breaking ofY and remaining in the tissues as a foreign body. Sometimes it is better to push the arrow on and extract it through the counterpuncture. Indian arrows' were frequently poisoned with rattlesnake venom or with earth containing tetanus germs, and Schell found it a universal custom to dip the points in blood which was allowed to dry on them; but such practices are rare at the present day. Tooth wounds, especially those due to human bites, are apt to be severely infected. Dog bites are less dangerous than those of cats, rats, and other domestic animals. Monkey and parrot bites are not very rare. I have treated a case of mole bite. Poisoned Wounds. — Under this heading it is convenient to consider snake bites and insect-stings. The latter are seldom serious in this part of the country, but in the tropics are sometimes fatal. The lesion consists in a localized, occasionally a spreading cellulitis, which is treated by evaporating and antiseptic lotions. The pain of stings is quickly allayed l)y plastering the bite with liquid mud, which should be washed off so soon as antiseptics are available; aqua ammonise also relieves the pain and neutralizes the acid poison, S7ial-e Bites. — Snakes (ophidia) are divided into two main classes, the Colubrines, mostly harmless, and the Viperines, usually poisonous (thauatophidia — death-suakes). To know whether the injury is from a harmless or a poisonous snake, the bite should be examined: "If the snake is harmless, two uniform rows of tooth marks will be found; if there are two or more distinct fang-marks, with or without tooth- marks, the snake is poisonous" (Fig. 123) (Mason, 1907). The venom is contained in a sac at the base of the hollow fang, which is on the upper jaw; this sac is compressed by the muscles which close the jaws, and the virus is squirted through the hollow fang much as through a hypodermic needle. Repeated biting soon empties the poison sac, and the snake is then comparatively harmless until more virus has been secreted. POISONED WOUNDS 171 The most iniportaiit coiistituciits of snake venom are a glol)uliii aixl a peptone. Tlie former destroys the coagulability of the l)loo(l, and pnxhiees moleeiilar changes in the vessel walls; this accounts for the extra\asation and hemorrhages (subcutaneous, gastro- intestinal, renal), which are characteristic of snake poisoning. The j)eptone produces locally "rapid edema. i)utrefaction, and sloughing without extravasa- / / \ •. • .• "■ * tion; constitutionally, it in- / : •. ". • .' '; creases blood-i)ressure, acceler- I '■ : • '•[ • . . • ates the respiration, and often ; ". ;" : •. : \ '• causes convulsions." (Mason, • ". • •. : \ \ 1907.) In rattlesnake bites, • : : ■ • ; • ; almost the only kind seen in • \ .• "•. • ; this country, death occurs in • • ' ' from 12 to 25 per cent, of cases, Fiq. 123.— Tooth marks made by snake USUallv within twenty-four to bites: on the left a harmless snake; fang- , . "^ . , TA ii i> marks in the centre and on the right indi- thirty-SlX hours. Death irom cate a poisonous snake. cobra bites, which are frequent in India, and not very rare in the PhiUppines, occurs usually in a few hours. Bites of copper-heads and moccasins are not so fatal, though amputation may be required for sloughing, or septicemia may kill at a later date. Treatment consists, locally, in the immediate application of a ligature or tourniquet around the limb above the wound, and in suction of the punctures by the mouth, or by cupping glasses when available. The venom is not poisonous when taken by mouth, if the stomach is full; but it should of course be spat out. Free incisions will make suction more effective. Amputation or excision of an unimportant part may be done. The ligature should be used inter- mittently, admitting only small doses of the venom into the circula- tion at one time; and when the wound is far enough from the trunk to make it possible, it is well to apply a high and a low ligature alternately. Mason also recommends that the limb be bandaged from its two extremities toward the wound, so as to squeeze out all the venon possible. The best local applications after free incision are oxidizing agents, such as peroxide of hydrogen, or 1 per cent, solutions of potassium permanganate or chromic acid. The actual cautery (hot coals, burning gun-powder) should be employed if these remedies are not at hand. Local treatment should be prompt, as it is probably useless after the lapse of half an hour. Constitutionally alcoholic stimulants are indicated, being pushed to the point just short of intoxication. Strychnin is considered valuable. Calmette's serum (antivenene) should always be employed when available; hypodermic injections of 10 to 20 c.c. of the stronger serum are given as soon as possible. Gastric lavage and catharsis are indicated to remove the venom excreted into the gastro-intestinal tract. Hope should not be abandoned too soon, some remarkable recoveries being recorded after the prolonged use of artificial respiration. 172 INJURIES AND THEIR EFFECTS GENERAL EFFECTS OF INJURIES. Shock. — The immediate constitutional effect of injury is named shock. A se^'e^e grade of sliock is called coUapse. Altliough no \ery accurate knowledge of the pathogenesis of shock has yet ))een o})tained, in spite of the elaborate experimental investigations of Crile (1899), and others, it is certain that its most important features are due to interference with the vaso-motor mechanism, resulting in marked jail of hlood-y res sure. The action on the vaso-motor centre takes place through the nerves supplying the injured part, and injuries of regions endowed with more highly specialized nerves are more apt to produce shock than injuries of other parts. Severe, even fatal, shock occasionally follows injuries accompanied by insignificant traumatism to the body tissues. Shock is especially apt to occur from injuries of the larynx, and of the viscera, particularly those of the upper abdomen, involving the splanchnic, and those of the thorax involving the cardiac plexuses. Injuries of the genitalia are frequently accompanied b}' marked shock, when the nerves of the spermatic cord are bruised or injured. Extensive burns and scalds, affecting immense numbers of peripheral nerve endings, are followed by marked shock. Lacerated and contused wounds, gunshot wounds, mangling injuries, and crushes are often accompanied by an extraordinary degree of shock. Henderson (1908) has proposed the theory that shock is due chiefly to loss of the carbon dioxide constituent of the blood, a state to which he applies the term acapnia; and as carbon dioxide is a W'cU known stimulant of the pressor mechanism of the vaso-motor system, causing rise of blood-pressure, it is not improbable that the shock which follows eventration of the intestines in certain operations may be partly accounted for in this way. Predisposing Causes. — General debility, extreme youth and age, and organic disease of the heart, kidneys, or other viscera, are among the predisposing causes. Exposure and chilling of the body surface, if prolonged, will increase shock. Hemorrhage, by directly affecting the patient's vitality, and lowering blood-pressure, is probably the most important cause of all. Prolonged anesthetization acts in a similar manner, chloroform causing lowering of blood-pressure from the very first, ether only after long administration. Symptoms. — The patient, if not stunned by the injury or suffering from cerebral concussion, is conscious, his mind sometimes being clear and alert, but more often semi-stuporous, as if the effort even to think were exhausting. The face is pale, the lips ashen or slightly blue; the entire body surface is pale, cold, and often clammy; the temperature is subnormal (Fig. 124); the eyes are staring or half- closed; there may be dimness of vision or actual blindness (from retinal anemia); the pupils are dilated, and react sluggishly to light; the respirations are shallow and rapid; the pulse is quick, fluttering, weak and frequently uncountable. Incontinence of feces is frequent, that of urine rare and usually portends a fatal issue. The patient SHOCK 173 DAY OF MONTH 5 !- 1 'l> t 7 8 UK] I < '.)•.) < tii; 'Jo J ^1- Fig. 124. — Shock and reac- tion. Case of multiple frac- tures; man, aged thirty years. Episcopal Hospital. lies inotioiilrss wluTcver plac<'' ncoclid, after heiiij;- deformed 1)\ the first iini)a(t; such wounds are more apt to he laceratcil and contused. Fig. 126.— Evolution of the iMiUct. 1. 3, 0.4.5-faIibr<- Springfield; 4, 0.3()-c:ilil)r< natural size. (Bryant and Buck.) old rounded musket t jacketed Springfield, 2, Minie Inillet ; ](■[ 190.-,. .Ml of At close range, the modern military bullet has what is known as an explosive effect; that is to say, any marked resistance causes its energy to be transmitted into the surrounding tissues. The more resistant the tissues, the more marked is the explosive effect. This is particularly noticeable in bone: if the spongy, expanded epiphyses are struck, there is little resistance offered and a grooved or tunnelled wound will })e produced (Fig. 127) ; whereas if the hard brittle diaphysis is struck the bone will be shattered (Fig. 128). Fluid-saturated or fluid- containing organs offer extreme resistance to bullets, because of their lack of compressibility; the brain, the liver, and the hollow viscera (if distended with liquid or semi-solid food) afford notable examples of this explosive action at close range. This destructive action is due to the missile's high initial velocity. Larger missiles (as the old round shot) with much lower velocity, even when almost spent, may ha\'e an equally destructive action. These facts are conciseh' expressed in the physical formula M = mv; that is, the momentum equals the product of the mass by the velocity, and if either the mass (as in the larger missiles) or the velocity (as in the modern military bullet) be sufficiently great, the momentum of the projectile, and hence its destructive action, will be correspondingly great. The bullet wounds encountered in civil life (suicide, homicide, etc.) as a rule are not produced by modern military bullets, but by softer, unjacketed bullets (jNIinie or Springfield) of low velocity (about 700 feet per second) ; the calibre varies from 0.22 to 0.40 or 0.45, but is usually large; and the wounds much more resemble those seen during the War of the Rebellion. As in civil life the bullet is softer, larger, and slower, it is more easily deflected and deformed, and almost invariably lodges in the patient's body; the wound is less clean cut, more lacerated and contused, than that produced by the 182 GUNSHOT WOUNDS military bullet; the bullet remains as a foreign body; and infection is much more frequent. In war it is very exceptional for the bullet to lodge in the patient's body; and owing to the greater velocity, the direct impact, and the rectilinear course of the bullet through the body, and its subsequent absence from the wound, infection is less usual. Unless a large bloodvessel or important organ IS wounded, death in war is seldom im- mediate; but it appears to occur in a larger proportion of cases since the intro- duction of the modern bullet, largely because of its penetrating power, which causes it to cut cleanly through or to groove large bloodvessels, instead of rupturing or contusing them. The latter result, commoner with the soft bullet, favored clotting and prevented death from hemorrhage on the field. General Characterof Gunshot Wounds. —As already noted, the wounds produced by artillery missiles are very severe, a limb being completely carried awav, the head being blown off, or a large portion Fig. 127.— Cancellous bone perforated by bullet (After Helferich.) Fig. 128. — Compact bone shat- tered by bullet. (After Hel- ferich.) Bi'LiJ'JT woi'xns 1S3 of tlu' trunk \m\v^ actiiiilly destroyed. In cixil life such injuries are oeeasionally eneouiiterred in Mastini; accidents, e.\i)losions, etc.; tlie wounds are severely lacerale(l and contused, and recjuire tiie usual treatment for sucli lesions. As the skin is elastic, a slowly n)o\injf cannon-i»all t're((nently lias j)ro(luced suhcutaneous injuries (fractures, rupture of xcssels, etc.), without laceratinjj; the intef^uuient; such injuries were formerly attril)uted to the "wind" of the hall. Bullet womtdf are in the nature of jjunctured wounds, and either pcncfnifr or perforate the body. If they merely penetrate, there is only a wound oj entruuce;^ if they perforate there is a wound of entrance and also one of exit (Fig. 120), except in very rare cases where the bullet makes a circuit within the body and emerjfes again by the wound of entrance. If fired at close range (usually not over 3 feet) there will be powder-marks around the wound of entrance. The wound of exit is usually, esi)ecially in civil life, larger than the wound of entrance, and its margins may be some- what everted. This is due to the bullet being deformed after striking, to the reduction in its velocity, to its carrying particles of flesh or bone before it into and out of the wound, or to it emerging sideways (no longer "end-on"). The wound of entrance sometimes seems smaller than the missile by which it was pro- duced, from the elasticity of the skin. If two bullets enter b>' the same wound, one may pass through and the other lodge; or they may emerge by the same or by difi'erent wounds; and two bullets may enter by different wounds and emerge by the same wound of exit. One bullet may traverse successively various parts of the body, making wounds of entrance and exit in both lower or upper limbs, or in a limb and the trunk, or if the limb is acutely flexed, traversing the same limb twice. The track of the bullet forms a sinus which heals by the ordinary processes of repair. The smaller the calibre of the bullet, the less likely is sloughing to occur; wounds by bullets of 0.22 calibre frequently heal without infection, even in civil life; those by bullets of 0.35 calibre or over almost invariably suppurate throughout their extent. Symptoms. — These are general and local. Shock is seldom marked in modern warfare, unless a vital organ is wounded, or unless the bullet has been fired at close range, w^ith explosive effect; in the heat 1 This may be within the mouth, or even within the anus or the external auditory meatus, when it is readily overlooked. Fig. 129. — 0.3S-calibre bullet wound in right calf. Wound of entrance on outer side: wound of exit on median side. Five days after injury. Episcopal Hospital. 184 GUNSHOT WOUNDS of battle, a soldier may be scarcely aware that he is wounded until he feels the trickling blood. Traumatic delirium occasionally is marked, sometimes occurrinji; at once, without any ii])])arent shock. Pain rarely is great, usually being merely a stinging sensation, as if from a smart blow with a whip or stick. Ilemurrhage seldom is profuse, unless from the wound of a large bloodvessel; under such circumstances it is likely that a large hematoma will form. Secondary hemorrhage (p. 177) is liable to occur at any time until all sloughs separate. Prognosis. — In warfare there is one soldier killed for every four, five, or six wounded ; and this proportion has been very little altered by the changes in military equipment. A large proportion of gunshot wounds, therefore, seems to be necessarily fatal; but in the remaining cases the prognosis depends almost entirely upon the treatment. By modern methods the death rate has been reduced to 5 or 10 per cent. The bullet wounds of war are not seriously infected of them- selves, and if kept clean the resistance of the patients usually is sufficient to ensure a good result, at least as regards life. Injuries of the trunk are more serious than those of the extremities, because of damage to viscera; but they are also less frequent. Injuries to the extremities involving bones, joints, or bloodvessles are more serious than mere flesh wounds. The positions of the wounds of entrance and exit frequently will enable the surgeon to exclude injury of important structures. Treatment. — In modern warfare the bullet seldom lodges, and even if it does, it rarely causes immediate trouble; hence it is not necessary to remove it. Every soldier is supplied with a "first-aid packet," and is instructed to apply the sterile gauze dressing so as to occlude the wounds of entrance and exit, fixing it in place with the bandage which is attached. Only in case of active hemorrhage is any operative treatment required on the battlefield; and if the he;norrhage, profuse at first, has ceased spontaneously, it usually is safer to apply a provisional tourniquet (Fig. Ml) and transport the patient, who w\\\ be much shocked, to the field-hospital (at least three miles from the front), than to undertake what may be a serious operation in unfavorable surroundings. Here, or preferably at the military hospital at the nearest base, the injuries to nerves, tendons, bones, etc., should receive suitable treatment. In civil life the bullet generally lodges, or is arrested by the skin on the opposite- side of the body; and from its large calibre and the nature of the wound it makes, frequently requires removal; and this is best accomplished within twenty-four hours or not until the inflam- mation has subsided. A bullet is best detected by the .r-rays; it may be accurately located by two exposures made at right angles to each other, with some suitable landmark as a guide (Figs. 130 and 131). If the .T-rays are not available, the track of the bullet may be probed (except in wounds of the abdomen), after thorough antiseptic prepara- tion. A porcelain-tipped probe (Fig. 132), first employed by Xelaton SMALL SHOT WOl'XDS 185 ii) the casi" of tlic (clcltnitfil (umutuI Garibaldi (18()2), will retain the marks ot" a soft lead hiillet, e\eii after the hlood has heeii rinsed ofV ill water; hut it is of little \ise in detecting- the modern hard jacketed bullets. The stem of a elay i)ii)C was used by IIei joints resnhed with hut a singh' ex(('])tion, where am])utation liad to he etwecn the knob of bone antl the diaphysis frf)m which it has been detached. As the detached knob of bone is voluntarily movable, the ring above it can be inclined in any direction, and through attached cords transmits the movements to the prosthesis. Mortality after Amputation. — Although this depends much more on the condition of the patient than on any other single factor, it is nevertheless proper for the surgeon to be familiar with the relative mortality of amputations for injury and for disease; and, in cases of injury, with that which accompanies primary, intermediate, and secondary operation; as well as the average mortality which attends amputation in different regions of the body. Primary amputations are those done before the inflammatory process has had time to develop — generally speaking, those done within twelve hours of injury; intermediate amputations are those done during the height of the inflammatory process; and secondary amputaiions are those performed after its subsidence, when the operation resembles that done for disease. As a rule, the lowest mortality attends primary' amputations; and though since the introduction of antiseptic methods there is less inflammatory reaction than formerly, nevertheless intermediary amputations still give the highest mortality. In the case of secondary amputation the results are not so good as they seem, many patients being too shocked for primary amputation, and dying before secondary amputation can be attempted. The fol- lowing table shows the death rate attending amputations in various portions of the body, for injury and for disease, as observed at the Episcopal Hospital, Philadelphia, 1900 to 1913 inclusive: Amputations at the Episcopal Hospital, Philadelphia, 190C 1-1913 Inclusi\t;. For injury. For disease. Recov- Mortality, Recov- Mortality, Region. No. ered. Died. per cent. No. 1 ered. 1 Died. per cent. Hand . . . 17 17 Wrist-joint 1 1 ■ • Forearm . 10 10 ii 3 6 Arm .... 30 29 1 3.3 3 2 1 33.3 Shoulder . 8 8 4 3 1 25.0 Interscapulo- thoracic 1 1 100.0 Foot ... 18 17 1 5.0 3 2 1 .33.3 Leg .... 54 49 5 9.2 16 S 8 50.0 Knee or knee-joint 6 6 3 1 2 66.0 Thigh . . . 27 25 2 7.4 18 10 8 44.4 Hip ... . 3 175 1 2 ^12 66.6 6.9 1 52 1 31 ... Total , . . 163 21 40.3 204 AMPUTATIONS It has usually been taught, and it is still stated by many surgeons, that amputations for disease are attended by a much lower death rate than those for injury. While this was perfectly true before the general adoption of antise])tic methods and modern methods of treating shock and hemorrhage, I tiiink the relati(jn is now reversed, though the extremely high mortality shown for amputations for flisease in the above table is to be explained by the fact that a large majority of the patients were suffering not from tuberculous arthritis or malignant tumors, l)ut from diabetic or senile gangrene. Yet the mortality in amputations for disease in this series is scarcely higher than that which attended amputations for injury before the antiseptic period. Treatment of Crushed Limbs. — The first thing to do is to control hemorrhage and combat shock. The limb should be held vertically, and an Esmarch band applied as near to the crushed area as practicable; the foot of the bed should be raised, and in cases of grave anemia the other extremities should be bandaged from the periphery toward the trunk (auto-transfusion) . The application of external heat, and other methods detailed at p. 175, should be employed for shock. If any vessels can be recognized in the wound they should be ligated ; and any projecting nerves should be injected with a sterilized eucain solution (2 per cent.), since by nerve blocking it is possible to check the peripheral impulses which cause shock. Amputation should be done as soon as the yatient reacts, or at once if the shock is not marked. // reaction once occurs no delay in amjmtating should he allowed, as the improvement frequently is only fleeting, unless the mangled limb is removed. The Esmarch band should not be left in one place more than four or five hours; sometimes, on removing it, no further bleeding will occur; but usually a little ooze persists, and the band should be re-applied higher on the limb. In a few hours its position should again be shifted (applying a second before removing the first, if necessary), since in this way it is possible to keep the bleeding checked without endangering the vitality of the parts above the wound. If the patient does not react, or if, in spite of the skilful application of the Esmarch band, oozing of blood persists, and seems to prolong shock, the surgeon must consider whether the mere presence of the mangled extremity is not detrimental, and whether by resorting to amputation at once he will not obviate the tendency to death better than by delay. In such cases delay is fatal with extremely few exceptions; but by prompt operation, even "under desperate circum- stances, a life is occasionally saved. In such a patient under my care at the Episcopal Hospital (March 12, 1909), I amputated the thigh, and though the pulse could not be felt for nearly two days subsequently, recovery ensued. In such cases speed in operating is important; the time consumed need not exceed ten or fifteen minutes. SPECIAL AMI'l'TA TIONS 205 SPECIAL AMPUTATIONS. Amputations of the Hand. — Though removal of portion of the hand is ro(iiiiren- tations at the knee, in which a section is removed from the femoral condyles. Two methods are in use, a long anterior flap method, and a hiteral Haj) method; the hitter is more appHcable to disarticulations, when the cicatrix falls between the condyles. But the anterior Hap metlKxris I)(>tter c\-en in such cases. In disarticulations the i)atella Fig. 170. — Stump of leg eight weeks after amputation by Ashhurst's modifica- tion of Sedillot's method. Episcopal Hospital. Fig. 169. — Amputation of leg by long external and short internal flaps. (.\shhurst's method.) Fig. 171. — Stokes' osteoplastic supra- condj'lar knee amputation, patella utilized : shaded parts are those brought in apposi- tion. (Farabeuf.) should be retained if possible; or its articular surface may be removed by a saw, and applied to the sawn surface of the femoral condyles (transcondylar amputation of Gritti, 1857); or to that of the femoral shaft (supracondylar amputation of Stokes, 1870) (Fig. 171). Amputation of the Thigh. — The circular, modified circular, and flap methods all produce an excellent stump in the thigh. The circular is best whenever there is a choice. If flaps are used, the posterior should be cut sufficiently long. The greater retraction of muscles 214 AMPVTATIOXS in the posterior flap carries the cicatrix away from tlie face of the stump ' Fii:. 172). Amputation at the Hip-joint ill. Thomson before 1777j. — Hemo- stasis is secured by Wyeth's method (1890): Two steel pins are used, each yg of an inch in diameter, and ten inches long; one pin is introduced close to the spine of the pubis, and after traversincr the adductor tendons emerges just below the tuberosity of the ischium; the other pin enters below and within the anterior superior spine of the ilium, traverses the gluteal muscles for about three inches, and emerges well above the level of the great trochanter; the points of the pins are immediately shielded by corks. A compress of gauze, two inches thick and four inches square, is laid over the femoral vessels at the brim of the pelvis, and an Esmarch band is wrapped very tightly five or six times around the hip between the steel pins and the pelvis (Fig. 173). Fig. 172. — Ami>utation of right thigh Fig. 17.3. — Wyeth's pins, and Esmarch (anterior-posterior flapsj. Episcopal band, for hemostasis during amputation at Hospital. the hip-joint. Antero-posterior Flap Method Guthrie. 1815). — The flaps are cut from without inward, ^ with a moderately short knife; the posterior is formed first, the incision commencing above the trochanter, and crossing the back of the thigh in a curved line convex downward, to a point in front of the tuber ischii; the anterior flap is then outlined, extending at least five inches below the joint (Fig. 174). These flaps being dissected up and the joint exposed, it is opened in front, the femur being forcibly abducted and hyper-extended, bringing the ligamentum teres into view; when this has been cut and the remainder of the capsule divided, any fibres on the back of the joint are severed, and the limb removed. In cases where Wyeth's method of hemostasis is not available, 1 Guthrie cut them bv transfixion. SI'ECIA L A MI'UTA TIONfi 215 Mini \\luT(> M()inl)iir<,'"s iiu'tliod (see below) is not emi)I()yed, the siir- jreoii iiiiiy ado])! either ])reliiniiiary lipition of the femoral vessels, by ail anterior racket incision (Larrc\, iSlTj, o|)eniiiK the joint from the front and (Jixidin^^ the remaining- tissues |)osteri«)rly from within ontward;' or he may adopt DielVeiiijach's method (1827), consistinjj of eireular ami)utation of the thigh followed by exeision of the head of the femur through an outer longitudinal ineision;^ or following lirashear's (1S()()) and Fourneaux-Jordan's (1879) method as modified by Semi {\S[y.]) may first disarticulate through an external incision and then, i)uneturiug the tissues on the inner side of the thigh, introduce a double elastic tube, and comi)ress in this wax the Fig. 174. — Incisions for amputation at the hip-joint by antero-poterior flaps. (Guthrie's method.) Fig. 175. — Incision forinterilio-ahdominal amputation tissues of both anterior and posterior flaps before removing the limb. Compression by a forceps tourniquet, somewhat like the forceps used for intestinal anastomosis, may also be employed (Lynn Thomas, 1898). The mortality of hip-joint amputation is now about 8 per cent, in disease, and 16 per cent, in traumatic cases (Wyeth, 1910), this vast improvement in the results being due chiefly to improve- ments in methods of hemostasis. 1 This is the "extirpation method" of Kocher, permitting careful dissection of malignant disease, and clamping and ligating every vessel as it is cut. It also permits nerve-blocking. 2 If there is nothin? to contraindicate subperiosteal excision, a more movable stump will be obtained. 216 AMPUTATIONS Interilioabdominal Amputation (Billrotli, 1885). — The incisions used are shown in Fig. 175. The horizontal and descending rami of the pubes are divided, and the ilium is sawed through just in front of the sacro-iliac joint, the entire intervening })()rtion of the pelvis being removed. Ransohofi' (1909) has collected thirty-four cases of this opei:9.tion, which is done almost solely for malignant disease; only twelve patients survived more than a few hours. The best method of hemostasis is Momburg's (1908), which has been used by both Pagenstecher (1909) and Bier with success, in interiho- abdominal amputations. This method of hemostasis had been em- ployed up to 1909 wath success in over thirty operations of various kinds. It consists in a])])lying an Esmarch band or thick rubber tube (size of the finger) four or five times so tightly around the waist, between costal arch and iUac crests, as to stop pulsation in both femoral arteries; the band is applied only after the patient is anesthe- tized, and before it is removed the patient is inverted and an elastic band applied around the base of each lower extremity, so as to prevent sudden anemia of the heart when the waist band is removed. CHArTKR IX. EFFECTS OF IIFAT AND (OLD; INJURIES BY ELE(TPvIC (I'UUENTS, LKillTNING, AND THE U()NT(;EX RAYS; SKIN-GRAFTING AND JM.ASTIC SURGERY. Burns and Scalds. The effect is essentially the same whether the injury is prodnced by flame (burn) or by hot li(ini(l (.s-mW). In scalds, however, the hair nsnally remains intact, while in bnrns it is singed. Symptoms. — Local symptoms vary with the degree of heat and the length of contact: mere singeing of the hair and a passing erythema may be caused by momentary contact of flame, while prolonged contact with some body at much lower temperature {e. g., hot water bottle) may produce a very destructive lesion. Burns may be classi- fied in three degrees: (1) Erythema. (2) Vesicles and Bullae. (3) Sloughing. The reactionary changes wdiich occur in the burned part are identical with those already discussed in the chapter on Infiam- m at ion. Fig. 176. — Scald of hand, second degree; twelve hours' duration; showing bullae. Episcopal Hospital. Constitutional effects of burns depend much more on the area involved than on the depth of the burn. A superficial burn may be attended by the gravest consequences, even death, if extensive; whereas a very deep burn, if it involves only a small area, may be almost unattended by constitutional symptoms. As in other injuries, the constitutional effects of burns may be divided into those of shock and reaction; and there usually follows, in severe cases, a stage of exhaustion. The pain is intense, and in extensive burns ma\' induce hyperpnea, which, according to the theory of Henderson (p. 172), produces acapnia, and so induces shock; patients may die in the first stage, without reaction. The unburned skin is pale, the patients 218 EFFECTS OF HEAT AND COLD feel chilly, and require to be covered up; the usual signs of shock are present. Often, however, reaction begins soon, sometimes before the patient is seen by the surgeon; and at this time yrosiraiion icith excitement or irauinatic deliriniu (p. 173) may dominate the scene. This stage lasts for a week or more, being accompanied l)y high fever, often with intense congestion of organs underlying the lesion (pneumonia, in thoracic burns; peritonitis, in those of the abdomen; meningitis in those of the head). There is a tendency to fatty degener- ation of all organs; the liver, spleen, and lymph nodes may be enlarged; the urine is scanty, of high specific gravity, or entirely suppressed. The bile is believed to be abnormally toxic. The blood is prone to Fig. 177. — Ulcers resulting from exten- sive burns received three months pre- viously. Episcopal Hospital. Fiu. 178. — Same patient, two months later, after complete cicatrization. Epis- copal Hospital. thrombosis, and capillary embolism is not infreciuent; there is hyper- leukocytosis and polycythemia; hemoglobinuria and albuminuria may exist. In rare cases duodenal idceration (Curling, 1842), with hemorrhage or perforation, develops, possibly from excretion of toxic substances through Brunner's glands, or as the result of embo- lism.^ The patient is excessively thirsty, but constantly vomits what is taken into the stomach; there may be septic diarrhea; he feels hot, is restless, and tosses off the bed-clothes. If he survives this 1 Alexander (1912) observed this complication in four out of twenty-seven patients with extensive burns. liURNS AND fiCALDS 210 stafi;c, tlicre follows that of cxliaiistioii, with lu'ctic fever, profuse siip- ])uratioii (►f the wounded surfaces, and |)(Tha])s metastatic (especially subcutaneous) abscesses. Death from Bums may be (hie to shock, to visceral complications, to (wIkuisIIoii, or to Iwuioh/sis and aufo-iidoxicaiioii. Amouj^ the visceral complications may be included edema of the glottis, from inhalation of steam or hot smoke. In fatal cases, death usually occurs within forty-eight hours. Prognosis. In local burns prognosis as to life is good, even if the part be much deformed by subsequent cicatricial contraction. Burns of the trunk are more serious than those of the extremities. If a burn in\()lves more than one-third of the body surface it usually is fatal. (General burns are always fatal. Jiurns are i)articularly serious in infants, the aged, those of intemperate habits, those with diseased kidneys, etc. Treatment. — The indications in all cases are to control the pain, to coDihdt flic sliocli, and to prevent infection. In severe cases, where death is antici])ate(l, the most that can be done is to ])romote euthan- asia. This is best accomplished by the use of morphin hypodermic- ally, and the immersion of the patient's body in a bath of saline solution at about blood-heat. Shock is combated as described at p. 17o; especially important is the dilution of the blood by saline solution, which relieves toxemia and restores the fluid contents depleted by discharges from the burned surfaces. Prevention of infection involves local treatment of the lesions; anything which protects them from the air lessens pain, and in extensive burns nothing is so satisfactory as the continuous bath, which should be kept warm and clean by frequent change. In burns of less extent it makes little difference what dressing is applied, so long as it is aseptic, and absorbs or does not dam up the discharges. Spray the burned surface lightly with peroxide of hydrogen, and surgically cleanse the surrounding parts. Do not scrub the burns. Open bullae w^ith a sterile knife, and let the epidermis fall back in place as the serum escapes. Alex- ander had occasion to treat twenty-seven burned patients simulta- neously. He concluded that for burns of the first degree the picric acid dressing was best; for those of the second degree he preferred the boric acid solution bath, which was used for three hours at a time, with intermission of six hours; and for burns of the third degree he recommends the following ointment: ichthyol, gr. xlviii; ol. olivse, foij; lanolin, q. s. ad ,^iij. Picric acid dressi)ig: gauze soaked in 1 per cent, aqueous solution is laid on the burn and covered with absorbent cotton, not with waxed paper, as evaporation should be favored; the dressing is left in place four or five days. It should be used only over small areas, as constitutional poisoning has occurred (Rose, 1903). Senn's powder (boric acid, three parts; salicylic acid, one part) or Billrotlis powder (equal parts of starch and zinc oxide) may be applied to small burns, and forms a scab which need not be removed for several days. Carron oil, made by stirring linseed oil 220 EFFECTS OF HEAT AND COLD and lime water into a thick paste, is very grateful to the ])atient. So soon as granulations have formed, the burn is treated as an ordinary ulcer (p. 54). Fig. 179. — Sanio patient as Fig. 177, one year later, after extensive plastic operations. Episcopal Hospital. Fig. 180. — Same patient one year after complete cicatrization, showing result of extensive plastic operations. Episcopal Hospital. When much skin has been destroyed, healing will be slow, and skin-grafting should be employed. Amniotic membrane has given some good results when grafted on burns. A very large granulat- ing surface should not be dressed all at one time, for fear of ex- hausting the patient; it is better to dress half the burned area on alternate days. If the patient is kept in a hot room the burned areas may be exposed to the air, no dressing being employed. Great care must be exercised by proper use of splints, etc., especially in burns about flexures of joints, to prevent undue cicatricial contrac- tion; but in some cases healing Ik;, isi— Dffnnnity from burns of can be sccurcd Only as the result feet. (Dr. \\liart(ju's case.) Children's >. i „^ /T7,- „ i '-'7 „.,J Hospital. or such a process {b igs. 1 / / and F RUST-BITE 221 178), iind the (let'orinity must Ix* overcome hy siihsecnieiit pliistic operations (Fij^s. 179 and ISO). In sexere grades of det'ormity, witli paiiiliil sears which pre\ent conser\ative operations, amputation may l)e necessary ( I*'i,<^. ISl ). Effects of Cold. In many ways these" are anah)gous to those ])ro(hiced hy heat, and (U'pend more on tlie hMi<^th of the exi)()sure than on the intensity of tlie cold; moist cold, especially in a high wind, is much more apt to ])roduce serious effects than a still, dry cold. Constitutional Effects. — Among predisposing causes are hunger, fatigue, alcoholism, etc. There occur ])ainful sensations in the extremi- ties, perhaps chills, followed by uncontrollable lassitude, somnolence, coma, and death if the patient is not roused. The causes of death are cerebral anemia (sudden and progressive chilling); cerebral con- gestion (slow and continuous chilling); or embolism, in cases of sudden reheating (Lebastard). Persoihs apjjarenfly dead should be kept in a cool room, and treated by artificial respiration and gentle frictions with evaporating or stimulating liniments; when reaction commences (perliaj)s not for several hours), the temperature of the room may be raised gradually, stimulants administered, and the patient wrapped in blankets. Recovery has followed after being buried in the snow for eight days (Tedenat), and when the rectal temperature had fallen as low as 74.6° ¥. (Xicolaysen). Fig. 182. — Frost-bite of second degree; duration, four days. Episcopal Hospital. Frost-bite. — The local effect of cold is analogous to that of heat, and may be classified in three similar degrees: Erythema, Bullae, and Eschar, The exposed part, especially the fingers and toes, nose, cheeks, ears, or the penis, becomes first the seat of congestion, attended by some tingling and pain; soon, however, the part becomes blanched, numb, and stiff", and to all appearances dead. This stage is well exemplified when local anesthesia is produced by the ethyl chloride spray. ^Yith proper treatment, the local destruction may go no 222 EFFECTS OF ELECTRIC CURRENTS further; if this is neglected, vesicles and bulUe form (Fifj. 182), and if the cuticle is destroyed and infection follows, painful ulcers develop which are long in healing. Finally, the freezing may be so intense that a local slough, or gangrene of an entire limb may occur, the larger arteries and veins being thrombosed. Treatment of milder degrees of frost-bite consists in gentle frictions with snow or iced water until sensation is restored; the part, which now begins to tingle and burn, may next be painted with silver nitrate solution (4 to 10 grains to the ounce), which allays these symptoms; the part is then protected from injury and maintained at an even temperature by absorbent cotton. When gangrene threatens, vertical suspension of the limb should be adopted (v. Bergmann, 1873) with immobilization by splints; as the swelling subsides the circulation improves. The resulting sloughs are treated as advised in Chapter II. Amputation should not be done until the line of demarcation has been established. Pernio or Chilblain is a vaso-motor disturbance of the skin following previous frost-bite of mild degree. It develops as the result of sudden variations in the temperature to which the part is exposed. Chilblains occur in parts most exposed to frost-bite, and are especially common in the anemic and run-down. A patient once affected- is prone to have recurrence of chilblains on slight provocation. The symptoms and treatment are much the same as for mild degrees of frost-bite. Constitutional treatment should not be neglected. Electric Currents. — These produce local effects (electric burns) and general effects (electric shocks). The former are more severe the less the area of contact, while severe shocks and milder burns follow broader contacts. The burns do not differ from those due to other causes, except in their extreme slowness in healing; Da Costa (1910) warns against use of corrosive sublimate solutions as very irritating. Skin-grafting usually is unsatisfactory, but a plastic opera- tion may succeed. The constitutional eflfects of electric currents are practically identical with those due to lightning strokes. Lightning Strokes. — Death may l)e instantaneous. Stunning almost always is produced, and burns frequently exist at the points of entrance and exit of the current; they resemble burns due to electric currents; arborescent marks, typical of lightning strokes, are attributed to disorganization of blood in the vessels. Persons apparently dead may recover after many hours; the usual condition of a patient just after being struck by lightning resembles that seen in concussion of the brain. Treatment consists in artificial respiration, external heat, and other methods advised for shock (p. 175). X-ray Dermatitis. — This affection, carefully studied by Codman in 1902, is seldom seen except as the result of repeated and prolonged exposure to the llontgen rays; before their danger was understood, skiagraphers took no precautions to protect themselves from exposure, and a dermatitis affecting the fingers was not unusual. The danger to patients is extremely slight, especially since modern methods SKIN-GRAFTING 223 pcniiit vtTV sliort exposures. The dermatitis does not develop for se\('ral da\s after exi)osure, and then is eharaeterized l)y sliji;ht erythema, witli piii;mentation and exfoHation of ei)i(hTm; a severer degree is evideneed hy the formation of vesicles and hiilhe, while the third dej^ree involves a sloui,di of the entire skin. Eventually, (lystro])Jues of the nails, keratoses, and ej)itheli<)inas may occur. TrciitiiH'ut. — No further exi)osure should he allowed, even if the patient thinks himself well protected hy leaden shields, etc. For the intense ])ain which exists during the extremely slow casting of the slough, alkaline astringents give the best results. Ointments are said to favor carcinomatous changes (Leonard). When these occur, am])utatiou is necessary. Therapeutic Uses of the X-ray. — These should be applied by an exi)ert Rontgenologist in consultation with a dermatologist. Some cases of lu])us, a few of keloid, and occasionally a case of superficial epithelioma may be cured, at least temporarily, by periodic exposure to the .r-rays. Their action appears to consist in stimulating an over-production of fibrous tissue, by which the growth of the cellular elements is arrested or abolished. After operation- for carcinoma, and in inoperable cases, systematic treatment with the .r-rays may delay recurrence, diminish pain, and greatly promote the patient's comfort. SKIN-GRAFTING. In cases of extensive ulcers resulting from burns or other causes, the practice of skin-grafting often not only accelerates healing, but may be absolutely necessary to bring it about. For the grafts to "take" well, it is essential that the granulating surface approach in type to that of the "healthy ulcer" (p. 54). There are three principal methods of skin-grafting, known by the names of Reverdin (1869), Thiersch (1874), and Wolfe (LS75), or Krause (1893). In all of these methods the granulating surfaces must first be ijreparcd for the recep- tion of the grafts. Roberts (1909) recommends dressing the part for several days previous to the grafting operation with gauze soaked in formaldehyde solution (1 to 200); this renders it sterile, and the tops of the hardened granulations are then gently scraped off with a sharp razor, just before applying the grafts. The ulcer is then washed with sterile saline solution to remove the antiseptics. The slight bleeding is checked with pressure by sterile gauze. The best sites from which to obtain grafts are the adductor surfaces of the thigh, the inner surfaces of the upper arms, and the lateral abdominal and thoracic walls; hairy skin is not suitable for grafting, as, apart from the deformity which might result from reproduction of the hair, it is difficult to sterilize and less apt to grow successfully than more delicately formed skin. The region from which the grafts are taken also must be prepared as for an aseptic operation. Antiseptic methods are not successful. 224 SKIN-GRAFTING Reverdin's Method. — Minute particles of the cuticle are raised on the point of a needle, cut off with a sharp scalpel, and at once transferred to the granulating surface, previously prepared. As many such grafts as may be required (a score or more) are a])plied over the ulcer, with the epidermic side upward, at close intervals; gently pressed down on the granulations, and held in place by strips of rubber tissue; space should be left between the rubber strips, to permit escape of discharges, and these are absorbed in sterile gauze dressings held in place by a. light bandage. The part is suitably splinted, and need not be dressed for four or five days, when it will be found that many of the grafts have taken, and may be recognized as minute islets of bluish-white epiderm growing in the centre of the granulating area (Fig. 183). In time these islets coalesce, and a number of small ulcers surrounded by epiderm replace the one large surface. Fig. 183. — Skin-grafting by Reverdin's method, in a case of burns of leg. The white spots on the surfaces of the ulcers are islets of new-formed skin. Episcopal Hospital. Thiersch's Method. — Long strips of epiderm, with only the most superficial layer of the cutis, are cut by means of a ^'ery sharp razor, with a rapid sawing motion, while the skin is held taut. The skin and the razor should be moistened with saline solution, to facilitate the process. The long grafts are then at once transferred to the granulating surface, pre^'iously prepared, and spread in place, covering nearly its entire surface. Dressing is similar to that for the Reverdin method. Thiersch grafts are more difficult to cut, require a general anesthetic, and are less apt to grow than the smaller grafts of Rever- din; but if they do grow, the healing of the ulcer is very much more rapid, and the resulting scar less conspicuous. Fig. 184. — Ulcer from compound fracture. Wolfe skin-grafts from amputated leg. Episcopal Hospital. PLASTIC SURdEHY 225 Wolfe-Krause Method. Tlu' iMitire thickness of the skin is trans- planted, l)nt witliont any snhentaneons tissue. Tlie j^ral'ts may he ohtained from the i)atient's own hody, or from the health\' tissues of a recently amputated hmh. As a rule, pieces an inch in diameter are large enoujjh, leaving space for discharges from the ulcer (Fig. 184). The entire operation should he dry, and al)solutel\- asej)tic. Wolfe grafts may also he applied to the wound at the time of oper- ation, and are i)referal)le for such use to Thiersch grafts, which latter are hetter suited for apjilication to granulating surfaces. PLASTIC SURGERY. The object of plastic surgery {anaplastii) is to restore or to improve the function or appearance of a part, deficient congenitally, or through disease or injury, lentil within a few^ years its field was limited to the skin and subcutaneous tissues (including mucous mem})ranes), but recently the formation of new joints (p. 471), transplantation of bone (p. 504), etc., have been done. Cinematoplastic amputations (p. 202) and prosthesis by subcutaneous use of paraffin (p. G20) are parts of plastic surgery, as are certain operations on the female perineum and vagina (Chapter XXIX). Its more limited field alone will be discussed here. The operation consists essentially in shifting flaps of skin and subcutaneous tissue, attached by one or more pedicles, so as to cover in defects left by excision of morbid structures. Such operations will not succeed unless asepsis is maintained, and unless no active disease exists in the parts on which the operation is done. Lupus and syphilitic ulcerations must be healed, and the disintegrating process at a standstill before any plastic surgery is attempted. Another maxim of extreme importance in plastic surgery is to do too little rather than too much at each step of the operation, which is thus often better divided into several sittings. Plastic operations may be classified as follows: 1. Anaplasty by simple approximation, as after excison of any tumor in which the wound edges can be brought together; in the operation for hare-lip, etc. 2. Anaplasty by transfer of flaps from the immediate neighborhood, by gliding, stretching, etc., as in operations for deforming cicatrices from burns, and in the Indian method of rhinoplasty (p. (V21). 3. Anaplasty by transfer of flaps from a distance: (a) Bv o?ie migration, as in the Italian method of rhinoplastv (p. 621)- (b) By successive migrations (method of Roux), as from the abdomen to the arm, and then from the arm to the face. 4. Anaplasty by readjustment of totally severed parts, including skin- grafting, transplantation of bones, joints, etc. The simpler the operation the more successful it is likely to be; hence the simpler methods always should be tried first, unless mani- 15 226 PLASTIC SURGERY festly inadequate. Cicatricial tissue usually should be excised and not employed in plastic surgery, as it is very apt to slough. Occa- sionally, however, where a fold of cicatricial tissue exists (as in the knee or elbow) it will be possible to split it, forming two flaps; and if the splitting be done by a Z-shaped incision, on straightening the limb two lax flaps will be available to cover in the flexure of the joint. In all plastic operations great gentleness should be used in manipulation; strict hemostasis by the finest ligatures must be secured; and accurate, but not too tight coaptation must be procured. The flaps should contain a moderate amount of subcutaneous tissue and their bases should be broad and should contain the main vascular supply; and the flaps should be made of sufficient size, especially when cut from tissues naturally lax (neck, scrotum), as in them retraction is greatest. When flaps are transferred from a distance, or when the base of the flap is much twisted in adjustment, the base must be divided (to restore contour) in from one to three weeks after the first stage of the operation. Diagrams illustrating the commoner varieties of plastic operations are given in Chapter XIX. CHAPTER X. SURGEin' OF THE BLOOD VASCULAR SYSTEAL Hemorrhage. This is tlic natural couscciiu'iicc of injuries which sever the walls of bloodvessels. Hemorrhage may l)e apparent, when it occurs in an open wound; or concealed {internal), when it takes place into one of the natural cavities of the body. Suhndaneous hemorrhagic attended l)y extravasation or formation of a hematoma, has i)een mentioned at p. HiO. The signs of hemorrhage are both local and constitntional . The local signs of venous and arterial hemorrhage are different, but the constitutional signs are identical. Venous hemorrhage is characterized by the darker, bluish color of the blood; by its flowing in a steady stream, not in spurts; and in most cases of wounds of the extremities by the ease with which it is arrested simply by elevation of the part. .Arterial hemorrhage occurs in rhythmic jets, and the blood usually is of a distinctly redder tinge. Constitutional Signs of Hemorrhage. — As the \olume of blood within the vascular channels is rapidly lessened by hemorrhage, the heart begins automatically to pulsate more quickly. A steady rise in the pulse rate is one of the surest signs of hemorrhage. As the quantity of blood in the system decreases, faintness comes on: there is thirst, rapid and sighing respiration (air-hunger); the skin becomes blanched and clammy; the lips and conjunctivae are pale; the ears ring; vision fails; specks and blackness float before the eyes; restlessness and delirium come on; involuntary dejections may occur; and with one or two gasps the patient may seem dead. At this stage bleeding may cease spontaneously, owing to the diminished force of the circula- tion which permits thrombosis; but it may begin again when reaction sets in. After very severe or repeated hemorrhages, faintness is prone to recur; and the patient may be feverish and delirious for several days. Slow hemorrhage is much less serious than profuse, sudden bleeding. Patients in early adult life bear hemorrhage better than infants or the very old; and, as a rule, women bear it better than men. Hemophilia is the name given to an obscure condition affecting males almost exclusively, and seemingly transmitted from one gener- ation to another only through the female sex. It is characterized by an abnormal and inveterate tendency to hemorrhage even from the most trifling injuries. Mere scratches, the extraction of a tooth, etc., frequently have caused such persons to bleed to death. The vice appears to reside in a loss of coagulability of the blood, though 228 SURGERY OF THE BLOOD VASCULAR SYSTEM it was long held that the bloodvessel walls were at fault. Blood oozes in profusion from the capillaries, and no local remedies are of much avail. The internal administration of calcium chloride may be tried; and the hypodermic injection of horse or rabbit serum, and even of diphtheria antitoxin has been used in some cases with benefit. Nolf and Herry (1910) secured arrest of the bleeding in nine cases by a single hypodermic injection of 10 c.c. of a 5 per cent, solution of peptone in 0.5 per cent, sodium chloride solution. This can be sterilized by boiling. Hypodermoclysis, intravenous injections of saline solution, and even direct transfusion of blood may be tried. Plate II, Fig. 2, shows the subcutaneous hemorrhages which followed the insertion of needles for hypodermoclysis in a patient with hemo- philia following circumcision; in this case recovery occurred after the direct transfusion of blood and use of diphtheria antitoxin. Yet a year later the patient was again in the ward with hemarthrosis (p. 387) following a trifling contusion of the knee. Spontaneous Arrest of Hemorrhage. — As mentioned above, bleeding sometimes ceases spontaneously. IMost very small vessels cease to bleed in a few minutes. In the case of capillaries, swelling of the endothelium occludes the lumen; in larger vessels there occur in addition contraction and retraction of the vessel walls. Contraction of a divided vessel is said to be an effort to restore the blood pres- sure to normal. Retraction results from the natural elasticity of the vessel, its ends being drawn back among the tissues, and its walls curling upon themselves so as to diminish the lumen, thus favoring coagulation. Treatment of Hemorrhage. — Temporary control of hemorrhage usually can be secured by direct pressure against the bleeding point, or on the main vessel of the part close above the wound, with eleva- tion of the wounded part. When possible a tourniquet or Esmarch band (p. 193) can be applied. For permanent control of hemorrhage the surgeon has many means at his command. 1. Position. — Elevation of the part has been mentioned already, and should never be neglected. It is a remedy so simple that it often is overlooked. Hold the wounded extremity up in the air until help arrives, if you can't do anything else. 2. Pressure. — Direct pressure on the wounded vessel always can be relied on to check hemorrhage. Use your finger if you have noth- ing else. A graduated compress may be held against the wounded vessel: this is made of pieces of gauze so cut as to form a pyramid when placed one on the other; the apex of the pyramid is placed against the wounded ^'essel, and the compress is held in place by a tight bandage. Hyperflexion of the elbow or knee over a compress will control bleeding below. Hemostatic forceps (Fig. 140) or other form of clamp may be applied directly to the wounded vessel, and in emergency the forceps may be left in place thirty-six to forty- eight hours. If the wound in the vessel cannot be found, com- press the main artery, when possible, at a higher point. This, and PLATE II Fig. 1. — Multiple nevi, affecting scalp, forehead, left foot, etc., in a baby aged Si^nnonths. Episcopal Hospital. Fig. 2. — Hemophilia, two days after circumcision, in a boy aged 8 years; shovving subcutaneous hemorrhages; that in right thigh followed an attempt to give hypo- dermoclysis. Episcopal Hospital. TliKATMEST OF IIKMORUII ACE 229 elevation of the ])art, will arrest, temporarily, any heiiiorrliaf^c. Or the woiiiul ina\' he packed with ^aiize or lint. Acupressure, (Sir .1. Y. Siinj)soii, IS.');)) is seldom emj)loyed at i)resent. A lonj^ and strong; steel pin is j)assed under the \essel, o('chidin8; Wyeth, 1876j, though not always expe/lient, to ligate large trunks close to the origin of branches, or tice versa. Usually, however, a clot forms proximal to the ligature, and, if the vessel has been tierl in its continuity ii. e., in cases where the vessel has not been divided j, a smaller clot usually forms on its distal side. These clots lie rather loosely in the channel, and are gradually con- verted into fibrous connective tissue by organization (p. '40). Should such a clot extend from the point of ligation past the origin of a large branch, there might be danger of emboli being carrie^^l away from it; hence it usually is considered proper not to apply a ligature within an inch or so of a large branch. Rule^ for Ligation of Wounded Arteries. — ^These rules are now classic in surger>-, and even today admit of verj- few exceptions: 1. In cases of primary hemorrhage do not ligate the vessel unless it is actually bleeding at the time. This rule applies to primarj', not to secondary' hemorrhage, and should be obserxed because: (a) bleeding may never recur; ib) it Is difficult to know which arter>- to tie unless the surgeon sees it bleed; and (c) search for the artery' may cause unnecessary' damage and lead to infection. Exceptions: (a) if the arterj' is seen pulsating in the wound it should be tied whether it bleeds or not: the operation is easy, harmless, and the remedy siu-e; (6) if the patient has to be transported a long distance or will be out of reach of a skilful surgeon, it will be proper to make a search for the vessel even if it is not bleeding nor easily found. 2. The vessel should be ligated where it bleeds and not elseichere, no matter what the condition of the wound. Because: (a) unless the wounded vessel itself Is seen, the surgeon may ligate the wrong vessel and fail to check the bleeding; (6) ligation even of the proper vessel at a higher point will not prevent recurrence of bleeding from the distal end, nor from the proximal end if a large branch intenenes, so soon as the collateral circulation is established. There are no exceptions to this rule (Guthrie, 1815; Matas, 1909j. But in certain regions (floor of the mouth, pehis) it may be necessarj' to expose the bleeding point by a counter-incision, instead of through the original wound. 3. Both ends of the wounded vessel should be ligated; and if it is only partly severed a ligature should be applied each side of the wound and the artery then divided between them. Because: when collateral circulation develops bleerJing from the distal end will occur even if this is not bleeding when the proximal is ligated. Exceptions: (a) when the distal end cannot be found, the wound should Ix* packed after ligation of the proximal end ; and (b) where both ends are easily found, where the injurj- was a clean incised wound, and where occlu- sion of the the vessel might cause gangrene, an attempt at circular arteriorrhaphy (p. 234) should be made. 4. Wound of a large vessel near its origin requires ligation of the wounded vessel below the wourul, and of the parent trunk above and TliF.ATMKSr or IIKMOiaHIMiE I'.W hcliiir the orifiln of the icunudcd hnnicli ( I'Mu'. IS')); mikI iroinid of a main irunk ucar ilw orujin of ' suppuration occurs, multiple abscesses forming along the course of the vein. There is moderate swell ing from the first, and if thrombosis is complete, and especially if a main trunk is involved, there is a certain amount of edema in the parts beyond. In advanced cases there is total disability of the affected extremity. The disease lasts from one to three or four weeks. Per- manent occlusion of the affected veins results in compensatory dilatation of collaterals, whicli may themselves be the cause of annoyance or (lisa})ility (Fig. 195). Diagnosis. — Predisposing causes must be considered (infections, injury), and the physical signs mu.st be accurately noted. By the latter means phlebitis may l)e distinguished from (1) Lj/nijjhangelfis (p. 2()d venous channels. In septic thrombosis of the oxarian veins, following ])uer])eral metritis, many surgeons ha\e attempted to prevent propagation of the thrombus by ligation above the limit of disease (('hai)ter XXIX). The operation of phlebotomy, with extrac- tion of the dot and suture of the vein is not so ])romising as arteriotomy for arterial eml)olism (p. 242), as the intima of the thrombosed vein is so diseased as almost necessarily to ensure recurrence of thrombosis; nor is the operation so desirable, since gangrene is less to be feared than from arterial occlusion. Wolff (1908) showed that in the lower extremity operative occlu- sion of the main arteries (137 cases) caused gangrene in 20 per cent, of cases; while occlusion of the femoral vein alone (31) cases) resulted in gan- grene in less than G per cent. In the upper extremity arterial occlusion (153 cases) caused gangrene in about 8 per cent.; only one case of ligation of the (axillary) vein was recorded, which did not result in gangrene. Pulmonary Embolism. — Pulmonary embolism, sometimes an alarming con- sequence of venous thrombosis, and often occurring at the onset of post- operative convalescence, has been considered at p. 178. Other forms of venous embolism, affecting the viscera (especially the liver), are of comparatively little surgical interest, except when occurring in pyemia. Arteritis. — Arteritis requiring surgical treatment is a much rarer condition than phlebitis. In chronic arteriosclerosis, with threatening or even developed gangrene (so-called senile or presenile gangrene), reversal of the circulation, as suggested by Carrel and Guthrie, has been attempted, by anastomosing the femoral artery and vein; the theor\' being that the veins, their valves being incompetent, ofTer less peripheral resistance to the outflowing blood-current than the sclerotic arteries. Though the operation appears to have been under- taken in about (53 cases (Zesas, 1912), there was cure or improvement in only 8 instances; whether such results justify the hazard of the primary operation must be determined for each case individually. (See Senile Gangrene, p. 61.) Arterial Thrombosis. — Arterial thrombosis occurs as a complication of wounds, compound fractures, cellulitis, etc.; but unless affecting the main artery of a limb, which is rare, its symptoms usually are 16 ' Fig. V.HJ. — Portion of thronibosod internal saphenous vein, excised at its juncture with the femoral. Episcopal Hospital. 242 SURGERY OF THE BLOOD VASCULAR SYSTEM overshadowed by those of the causative condition. When the main artery of a limb is affected, the symptoms differ only in the less sudden onset from those of arterial embolism, presently to be described. F. T. Stewart (1908) refers to 35 cases of traumatic arterial thrombosis, 31 of which terminated in gangrene. The treatment is the same as for embolism. Arterial Embolism. — Arterial embolism, when affecting the main artery of a limb, is a condition of great gravity. The clot usually is derived from one of the cardiac valves; it is detached from no apparent exciting cause, is carried away in the blood-stream, and if lodging so as to ])lug an artery of considerable size, presents charac- teristic and well marked symptoms. The patient suffers a sudden, acute, stinging pain below the site of embolism, in the distribution of the affected artery; the limb below becomes tingling, numb, or for a time the seat of burning pain; pulsation is absent below the site of embolism; and the limb gradually grows cold, bluish, livid, and the signs of oncoming gangrene appear (p. 60). Fig. 20 (p. 62) shows gangrene due to lodgement three weeks previously of an embolus in the popliteal artery, in a patient who three months before had embolism of a cerebral artery. Treatment. — When the embolus lodges in an accessible situation, and in one where sudden complete arterial occlusion habitually results in gangrene (especially the brachial at the elbow, the femoral and popliteal arteries), the surgeon should lose no time in resorting to arteriotomy and extraction of the clot (F. T. Stewart, 1908). This is a more promising procedure for embolism with secondary' thrombosis, than for primary thrombosis, since the healthier con- dition of the arterial coats in the former condition makes recurrence of thrombosis less likely. According to Le Conte and Stewart (1910) arteriotomy for thrombosis or embolism has been done in 7 cases; at least 3 of the patients died, and in none was gangrene prevented. Since the publication of these statistics one successful case of arteri- otomy for femoral embolism (aseptic) has been reported by Mosny and bumont (1911). Varix, Phlebectasis, or Varicose Veins, describes a condition in which the veins become elongated, dilated, tortuous, and pouched. Any veins may be affected, even those of bone; but superficial veins, especially the ^'eins of the spermatic cord and the saphenous ^'eins of the lower extremities, are most noticeably diseased (Fig. 197). The chief cause is gravitation, aided by obstruction to the normal venous current. Occupation (barbers, waiters, motormen, or others who stand for hours at a time), tumors, pregnancy, thrombosis (Fig. 195), or other factors producing obstruction, are all predisposing causes. Usually no one well defined cause can be found. The valves become incompetent, the blood stagnates, hypertrophy and sclerosis of the vessel walls occur, phleboliths may develop, and thrombosis may finally cause obliteration of the diseased veins. The symptoms of pain, fulness, weight, etc., are frequently disabling; in the lower VARICOSE VEINS 243 Fig. 197. — -Varicose internal saphenous vein, aged sixty-three years ; duration over forty years. extremities the perivascular tissues become thickened, liard edema develops, the nutrition of the skin suffers; trifling trauma produces an abrasion which fails to heal, and varicose ulcer results (p. 57). Profuse hemorrhage may occur from spontaneous rupture of a varix. Rup- ture of a deep varicose vein is attended by sudden stinging pain ("coup dc fouet") and subsequent appearance of ecchymosis. • Treatment may be pallia- tive or radical. The former includes api)lication of elastic bandages or stockings, after emptying the veins and reducing edema by elevation of the limb; the use of stimulating lini- ments, etc.; and attention to hygiene. Such treatment always should be tried first, and usually is efficient when the cause of the obstruction is temporary (pregnancy), or removable (tumor, etc.). In other cases, or when pallia- tive measures fail to relieve symptoms, operation is indicated. If the super- ficial veins are varicose as a result of thrombotic obstruction of the deep veins, no operation should be attempted unless elastic support with temporary obliteration of the varicosities produces relief and demonstrates the efficiency of the collateral circulation. Very occa- sionally varicosities due to this cause disappear spontaneously after a few vears, owing to the development of collateral circulation (Skillern, 1913). Operative Treatment. — Operative treatment consists in obliteration of the varicose channels at one or several points. Schede's operation (1877) is done by making a circular incision below the knee down to the deep fascia, thus dividing all the superficial veins; both ends of each divided vessel are then ligated, and the skin sutured. This operation also divides the superficial lymphatics and sensory nerves; sometimes is followed by edema, paresthesias, neuralgias, or trophic disturbances in the skin below; and, according to Matas, is followed by permanent cure in only one-third of the cases. Spiral division of the skin enables the surgeon to obliterate all the venous channels without severing all the- lymphatics, thus rendering edema less likely; but section of the nerves can scarcely be avoided. Tre?i- delenburg's operation (1890) consists in division of the main varicose trunk (usually the long saphenous above the knee) between two ligatures, the object being to break the column of blood, thus relieving pressure symptoms. It is suitable for those cases where only the main trunk, not its collaterals, is varicose; and is not suitable even for those cases if the saphenous vein is the seat of chronic phlebitis. According to Matas, 79 per cent, of patients treated by Trendelen- 244 SURGERY OF THE BLOOD VASCULAR SYSTEM burg's operation have been cured or' greatly improved. Multijde Phlebcctomi/, associated with the names of Madelung (1884) and Schwartz (1888), is, I beheve, the best operation in the vast majority of cases. Sections of the diseased veins, three or four inches long, ^are removed at the saphenous opening and in other parts of the thigh and leg, wherever the main trunks or their branches are most dilated ; the intervening portions become thrombosed, contract, and produce no further symptoms; and the greater portion of the diseased tissue is completely removed from the body, which is not accomplished by either Schede's or Trendelenburg's operation. If the surgeon wishes, he can remove the entire saphenous vein through one long incision; or by passing a curette over the ligated end of the main trunk, as practised by C. H. Mayo (1906), and ripping off its branches by subcutaneous tunnelling with this instrument, the entire vein may be removed through three or four small incisions. These methods, though more spectacular than multiple phlebectomy, which is a tedious procedure, are less sure, since the diseased collaterals are left behind. In many cases, moreover, the veins are calcareous, and so densely adherent to the perivascular tissues and even to the skin, that only a formal dissection can free them. I have always employed multiple phlebectomy, except in cases due to thrombosis of the deep veins; in these I have adopted a spiral incision for Schede's operation, thus avoiding excision of the only veins the patient possessed. Operations for varicose veins are not entirely devoid of danger: in large series of operations death from pulmonary embolism has occurred in 1 or 2 per cent, of cases; the skin frequently is difficult to sterilize, and in spite of care infection of the incisions may occur; occasionally phlebitis is a sequel. Hemangeiomas ; Telangiectases. — Under these terms are included various affections of the vascular system, whose proper classification has not been determined by pathologists. In the vast majority of cases they are cojigenital, or at least are noticed first in early infancy; the lesions usually enlarge more rapidly than the part in which they are situated, and from being insignificant specks at birth may become growths of alarming size in childhood or early adult life. Sometimes they assume the character of tumors, as descril)ed in Chapter IV, very occasionally seeming to possess malignant characteristics (in- filtration, recurrence). Nevus Vasculosus. — This may affect either capillaries or venules, its color (bluish, purplish, or red) depending upon the proportion of venous blood present. Capillary Nevi (Plate II, Fig. 1). — Capillary nevi occur in the skin, rarely in mucous membranes; they do not involve the subcutaneous tissues; they are red, or reddish blue ("mother's mark," "birth-mark," "port-wine stain"); they may be elevated above the surface of the surrounding skin, or may lie perfectly flat beneath a seemingly normal epiderm. They vary greatly in size. Elevation of the affected part does not cause them to shrink or become pale; nor does pressure HEMANGEIOMA AND NEVUS 245 blaiuli tlii'iii, unless very small, and then only momentarily. Tsually they are nuilti])le, are most frecjuent on the face and neck (])erhaps branchi()«;('nic) ; tend to ji^row lar); (-) Saccular (Fig. -0(»); and (3) Disscctinxj Aneury.s)ii.s. Tubular or fusiform aneurysms are those which involve the entire circunifereiice of an artery, and are rare even in the larger Fig. 205. — Fusiform anour\!5ni. Fig. 200. — Saccular aneurysm, with small mouth. internal vessels. Dissecting aneurysms are those in which the blood makes a channel for itself between the coats of the arterial wall for a variable distance, and again enters the arterial lumen; they are seen almost exclusively in the tho- racic or abdominal aorta. The saccular aneurysm, in which the dilatation involves a portion only of the arterial circumfer- ence, communicates with the vessel by a comparatively small orifice called the mouth of the sac; by progressive growth of a saccular aneurysm its mouth may become so lengthened as to cause the aneurysm to re- semble at first glance one of tubular or fusiform variety, especially on laying open the sac, when it will appear that there are two mouths present (Fig. 207, B). Though aneu- rysms usually are single, they may be multiple; and after cure by obliteration of one sac others may develop (Fig. 204). The sac of an aneurysm when first formed contains fluid blood; the eddying and partial stagnation to which this is constantly sub- FiG. 207. — Saccular aneurj-sm with large mouth; when opened it appears as if there were two orifices. 250 SURGERY OF THE BLOOD VASCULAR SYSTEM jected leads in time to the deposition of fibrinous clots on the interior of the sac wall. These are deposited in successi\e layers, constituting the laminated clot. This rarely l)ecomes firmly adherent in all spots to the sac wall, but is dissected loose by the eddying currents, thus preventing its organization. Should such firm adhesion and organiza- tion occur, and should concentric laminations be formed continuously, spontaneous cure of the aneurysm eventually might ensue by oblit- eration of its sac; but this is extremely rare. Causes.— The chief underlying cause of aneurysm is precedent disease of the vascular system; aneurysm is but a symptom of this disease; and in the immense majority of cases the vascular degenera- tion is a sequel of syphilis, ^ though chronic alcoholism, even without syphilitic affection, is saifl sometimes to be a cause. The immediately apparent cause, in most cases, is some sudden strain, exertion, or accident, which causes rui> ture of the diseased media at its most susceptible point; the vis a tergo of the blood- stream then causes progres- sive dilatation of the artery until a well defined aneurysm exists. Constantly recurring slight trauma is recognized as a predisposing cause in that it causes localization of arterial lesions where aneurysms later develop. Thus is explained the preponderance of aneu- rysm in the aortic arch and at the root of the neck, where not only is the cardiac im- pulse strongest, but where the arteries lie against bone (vertebrse, first rib, clavicle) and where each pulsation tends to bruise the arteries against this unyielding structure; the latter explanation is adduced by Barwell (18S2) to account for the frequency of popliteal (Fig. 208) as compared with brachial aneurysm. Localization. — In general terms, the aorta is affected in 42 per cent., the popliteal artery in 24 per cent., the femoral in 12 per cent., and the carotid, subclavian, axillary, and innominate in about 3 per cent, each — leaving the smaller arteries of the extremities to form about 10 per cent, of cases (Crisp, 1847). Popliteal aneurysm forms from 55 to 60 per cent, of those occurring in the limbs (Matas, 1910). Age. — Aneurysm occurs mostly in patients in active adult life; about two-thirds of cases are seen between the ages of thirty and fifty years, after arterial lesions have had a chance to develop, Fig. 208.^Poijliteal aueurysni, right leg. Dr. Harte's case. Pennsylvania Hospital. 1 This was streniiouslv denied bv Barwell (1882). SYMPTOMS OF AXE!'RyS.\f 251 and wliile sudden strains arc still IVccjiiciit. .SV'.r; It is seen in men al)()ut six or seven times as fre(iuently as in women, owing to the greater liability of the male sex to atheroma, and to their more labori- ous life. Occupations attended b.y violent exertion (porters, teamsters, soldiers, sailors) are regarded as })redisi)osing to the de\eloi)ment of aneurysm, as are diseases of the heart and kidneys, chronic gout, rheiiniatisni, etc., causing arterial hypertension and calcification. Symptoms. — These usually are of slow develoi)ment, though occa- sionally the ])atient is aware that "something has given way," expe- riences a sudden stinging pain, as the "coup de fouet" in rupture of deep varicose veins (p. 243), and on examination at once finds a pulsating tumor has formed. The symptoms of aneurysm may be considered as those peculiar to the aneurysm itself, and those due to its pressure on surroundi}ig parts. There is present a rounded or oval tumor, either apparent to the eye or appreciable to the touch; it is situated along the course of an artery; it is movable laterally but not longitudinally on the artery; and it is somewhat compressible and elastic (depending on the amount of laminated clot). An aneurysm becomes more or less flaccid by pressure on the artery above, and harder and more tense by pressure on the artery below^ the tumor. It is covered by healthy, non-adherent skin, unless in the last stages when rupture is about to occur. The affected part is more or less disabled, with muscular weakness, paresthesia, numbness, or edema (pressure effects) : pressure on nerves causes neuralgic pain or paralysis (of pupil, of vocal cord, etc.); on neighboring veins causes varicosities and edema; on arteries (perhaps the parent trunk) causes gangrene; on bones causes erosion, with intense boring pain; on neighboring viscera (trachea, esophagus, bile ducts, etc.), may cause serious disturbance in their functions. Aneurysms pulsate, synchronously with the heart: they are not merely lifted by the pulsation of the underlying artery, but as the blood enters the sac and swirls around in its interior the sac walls dilate, causing an extremely character- istic pulsation wdiich is both eccentric and expansile. The degree of aneurysmal pulsation depends on the size of the sac and of its mouth, and on the thickness of its walls; a small aneurysm with much thick- ened walls and a small mouth connecting with the artery will pulsate much less than one w^hich is large, thin walled, and possessed of a large mouth. Pulsation becomes more pronounced when the part is depend- ent and Avhen pressure is made on the artery below the sac, and may almost disappear when the limb is elevated and the artery occluded above the sac. When pulsation has been made to cease b}' the latter method, application of the hands over the sac will enable the surgeon to detect the entering blood when pressure is removed, and will make him appreciate the facts that the sac does not always become fully distended with the first impulse from the heart, and that the pulsation is eccentric and expansile, driving the hands not only further away from the underlying artery, but also further apart from each other. Pulsation in the artery below the aneurysm may be 252 SURGERY OF THE BLOOD VASCULAR SYSTEM much diminished, as compared with corresponding pulsation on the other side of the body; this phenomenon is due to pressure on the artery by the overlying aneurysm; while the fact that the pulse below the aneurysm may be delayed is explicable on mechanical grounds, the aneurysm acting as the air-chamber of an hydraulic ram. INIore- over, the arterial pressure distal to the aneurysm is less than in the corresponding healthy artery. Bruit, which is the peculiar whirring or rasping noise made by blood entering the sac, is present with very few exceptions (old thick-walled aneurysms almost full of clot); it occurs during cardiac systole, is therefore intermittent, and is loudest in aneurysms with large sac mouths; it may be made to cease by obliteration of the artery above the aneurysm, unless large collaterals empty into the sac; and in aneurysms of the extremities sometimes becomes louder when the limb is elevated. It may be transmitted centrifugally along the diseased artery. Thrill is to the hand what bruit is to the ear; but is much less marked than in arterio-venous aneurysms. Course and Termination. — Aneurysm is an incurable disease, and if left to itself first disables and then kills the patient within com- paratively few years. Apparent cure is only temporary, as other aneurysms ma}' develop or the first recur. By proper treatment, howe^Tr, symptoms may be relieved, individual aneurysms may be temporarily cured, and the life of the patient may be prolonged indefinitely (perhaps fifteen to twenty years) in comfort and reasonable usefulness (Fig. 204). Death finally comes slowly (from exhaustion, inanition, gangrene, etc.), rapidly (from pressure on trachea or larynx, on phrenic or pneumogastric nerve, from rupture and hemorrhage, etc.), or suddenly from syncope even without rupture. Diagnosis. — This is made by attention to the history and physical signs. Arterio-venous aneurysms usually follow penetrating wounds; other signs of vascular disease may be wanting; bruit is continuous (not intermittent except sometimes when the limb is elevated — Nelaton), is transmitted both centrifugally and centripetally; thrill is marked; and compression on the afferent and efferent arterial trunk does not cause such characteristic changes in the sac. Other vascular pulsating tumors are less well defined in outline, do not present eccentric pulsation, have little or no bruit, and are not neces- sarily placed in the course of a large artery. Other tumors may pulsate because they overlie an artery, but the pulsation is neither expansile nor eccentric, there is neither bruit nor thrill, and obliteration of the aft'erent or efterent arterial trunk, while it may cause cessation of pulsation, yet produces no other change in the tumor. Xon-pulsating tumors may be mistaken for an aneurysm with contents clotted; such grow'ths may be movable longitudinally as well as laterally, and present a different clinical history. iVn aneurysm which has become diffused or inflamed may be mistaken for an abscess (p. 49), but attention to the history, and a careful physical examination will almost surely prevent any confusion. TREAT MEM' OF ANEL'in'^M 253 Treatment. -This may be operative or non-operative. Under the latter licadinu are inchuled hyfjienic and dietic measures, such as alone are aj)pli(al)le to certain forms of internal aneurysm. All other aneurysms should be operated upon, and nothing is gained by delay. The end sought by operation is to prevent blood from entering the sac, thus allowing its obliteration. This may be attempted in various ways. The methods still in most general use endeavor to secure coagulation of the blood within the sac; these may be regarded as palliative operations. ]\Iost of them act by retarding the current of blood passing through the parent artery; others act directly on the contents of the sac itself. They inchide ])ressure on the afferent artery; compression of the sac itself (as by flexing the knee for pop- liteal, or the hip for inguinal aneurysm), ligation of the afferent artery, or of the efferent artery or one of its branches; injection of coagulating fluids; insertion of needles with irritation of the intima to favor throm- bosis; and introduction of metallic wire with electrolysis. Manipula- tion of the sac (Fergusson, 1857), in an effort to detach a clot which shall plug the efferent artery, should be mentioned only to be con- flemned. Radical operations comprise extirpation of the sac, with suture or ligation of the orifice or orifices into the parent artery; and Endo-aneurysmorrhaphy, which is the best method whenever applicable. Pressure. — The patient should be confined to bed, and kept on a low diet with very little fluid; this slows the circulation and favors thrombosis (Tufnell, 1864). The pressure may be either instrumental (by various forms of tourniquets), or digital (Knight, 1844), which is preferable. The afferent artery is compressed until the sac ceases to pulsate. Relays of assistants are required, each one keeping up pressure for from three to five minutes, being then relie\'ed by another who compresses the artery above or below the first point of compression before this is released by the fingers of the former assistant. In this way the circulation of blood in the sac is much diminished, favoring the formation of a laminated coagulum. Treat- ment is to be kept up for from two to four days, in sittings of about four hours once daily. After thirty-six hours hope of cure is much less, and continuation of pressure dangerous (sloughing, etc.). The method is most easily applicable to the femoral artery, for aneurysm of the popliteal. It should be employed only when endo-aneurysmorrhaphy or ligation are contraindicated, as in the very old and feeble, in those with serious visceral disease, etc., in whom the dangers of a cutting operation are excessive. The method is successful in perhaps half the cases treated. G. Fischer (1869), found that among 188 cases of aneurysm treated b}' digital compression, cure resulted in 121 (over 64 per cent.), and 38 of these patients were cured in less than three days; of 90 cases of popliteal aneurysm, 72, or 79 per cent., were cured by digital compression. LiGATiox. — This may be done on the proximal side of the aneurysm, or the distal, or on both sides. 254 SURGERY OF THE BLOOD VASCULAR SYSTEM Froximal Ligation. — The method of Hunter (1785) consists in applying a ligature some distance above the aneurysm, allowing small branches to convey blood from above the ligature through collateral circulation, into the sac of the aneurysm (Fig. 209). The advantages claimed for the Hunterian method are: (1) accessibility of the artery; (2) healthier condition of the arterial walls; (3) gradual obliteration of the sac by formation of laminated clot. But modern aseptic oper- ating renders the artery easily accessible at any site, and even if the arterial wall be diseased close to the sac (which is not certain), application of a ligature will strengthen it, and healing will occur normally. Objections to Hunter's operations are: (1) the existence of collateral circulation through the sac really is unfavorable to its Fig. 209. — Hunter's method of liga- tion for aneurysm: collateral circula- tion from above the ligature into the sac. Fig. 210. — Anel's method of ligation for aneurj-sm: circulation through the sac com- pletelj' arrested. complete obliteration; (2) interposition of two obstacles to the circu- lation (ligature and aneurysm) renders gangrene more likely, as does the exclusion from the circulation of collaterals arising between the ligature and the sac; (3) if the collateral circulation is successfully established through the main trunk, recurrence of the aneurysm is likely. The method of Anel (1710), revived in 1856 by Broca, con- sists in the application of a ligature close to the sac (Fig. 210); until recent years it was considered inferior to Hunter's operation, but aseptic technique has shown it to be quite as safe and but slightly more difficult; and its manifest advantages are that the circulation through the sac is completely suppressed and yet no additional obstacle is erected to the circulation, only one set of anastomosing vessels being required, instead of two, as in Hunter's operation. THE ATM EXT OF ANEURYSM 255 jNIatas, Di'lhct, WoIht, Kolilor, LeCoiito and Stewart all jjrefer Aiiel's metluxl to that (jt" Hunter. Distal lUjatioii also depends for its curative effect on retardation of the circulation within the artery, with consequent thrombosis in the aneurysmal sac. Bnmlors wet hod (1798) consists in ligation of the main trunk immediately distal to the aneurysm, no branch intervening (Hodgson, 1815) (Fig. 211); while the ''new operation" of Wardrop (1828) involves ligation of one of the main branches below the sac, or of the parent trunk below the origin of a })ranch (Fig. 212). These methods are inferior to proximal ligation, because less certain; but are still employed in places where the proximal side of the artery is Fig. 211. — Brasdor's method of liga- tion for aneurysm, applied for aneurysm of the common carotid artery (C). I, innominate; S, subclavian artery. Fifi. 212. — Wardrop's method of liga- tion for aneurysm, applied for aneurysm of the innominate (/). The common cartoid (C), and the subclavian (S) in its third portion have been ligated, permit- ting slight circulation through the thy- roid axis. inaccessible, as in Innominate Aneurysm, or large aneurysms of the first part of the Subclavian. For innominate aneurj^sm simultaneous double ligation of the common carotid and subclavian arteries is preferred, constituting Wardrop's method, since the subclavian is tied in its third portion below^ the origin of the thyroid axis and vertebral. Double Ligation, Above and Below the Sac. — When this is immedi- ately followed by incision of the aneurysm, evacuation of the clots, and packing of the sac, to control hemorrhage from collaterals entering the sac, it constitutes the operation of Antyllus (third century, a.d.); if the sac is opened first, the clots evacuated, the mouth of the sac 256 SURGERY OF THE BLOOD VASCULAR SYSTEM sought with tlie finger, and a probe passed up and down the parent trunk as a guide to the appHcation of Hgatures above and below the tumor, it constitutes the "old operation," which was temporarily revived by Syrae QSoT). At the present time the mortality from ligation is about 8 per cent.; there is, however, also the risk of gangrene, requiring amputation, which occurs in an additional S per cent, of cases (Delbet). Gangrene is due not only to sudden arrest of the circulation, but also to pressure on surrounding tissues by the thrombosed sac, and sometimes to embolism of the artery below the sac. E\en if a patient recovers and escapes gangrene, the symptoms from pressure (neuritis, edema, etc.), may be not only unrelieved but even aggravated by solidifica- tion of the sac. FiLiPi-xcTURE AXD Electrolt.sis; Wirinx. of Axeurysms. — Wiring was intrcxluced by Moore (1864), and modified by Corradi (1879) who passed an electric current through the wire coil. Fine gold or silver wire fXo. 28 gauge) is used, being inserted through a cannula which is plunged into the aneurysmal sac; from ten feet to as many yards of wire are introduced; the positive pole is attached to the wire entering the aneurysm (Hare, 1908), the negative pole being placed elsewhere on the patient's body, and the current (70 to SO milliamperes) is allowed to run for nearly an hour. This method may be attempted in certain cases of internal aneurysm in which death is imminent from rupture, or in which Tufnell's treatment (p. 253) (perhaps combined with repeated venesection — ^^'alsalva's method) fails to relieve urgent pressure s\Tnptoms, but in which liga- tion or endo-aneurysmorrhaphy are impossible. Thoracic aneurysms (aortic arch, low innominate) are to be localized by physical exami- nation and the ^-ray, and the camiula plunged directly into the sac; abdominal aneurysm is treated after exposing the sac by laparotomy. For thoracic aneurysm no other surgical treatment is possible, except in the case of innominate aneurysm, when simultaneous double distal ligation is preferable. In some cases of abdominal aneurysm endo- aneurysmorrhaphy can be performed, and is preferable if temporary control of the circulation can be secured. ^latas (1900) found that wiring and electrolysis resulted m apparent recovery in less than 20 per cent, of cases; in 1910 he condemns the method as a '"pureex- p>eriment, which is justified solely by the imminent and unavoidable danger of death from the progress of the disease itself." Eshner (1910) has analyzefl 36 cases of aneurysm, mostly aortic, treated by wiring; 9 patients died within ten days, 22 lived less than one year, and 5 survived for periods ranging from fourteen months to over eleven years. ExTiRPATiox OF THE Sac, known by the names of Philagrius (third century A. D.), and Purmann (1685), now finds an ardent supporter in Delbet. It removes the danger of gangrene due to pres- sure on surrounding parts by the clot-filled sac, as also the danger of embolism. For its successful performance it is necessary to secure T RE ATM EST Ob' AMCIUYSM lot preliininan' control of the circulation, when possible Ijy iij)plication of an elastic hand at the root of the linil), or even hy direct clamp- ing of the afferent and efferent artery. This latter method, however, may not prevent profuse recurrent hemorrhaj^e from collaterals empty inj^ into" the sac. The vein should be ])reserved, and if impor- tant structures are adherent to the sac that jxtrtion of the sac should be left behind. According to Delbet (19U7), among 8() patients treated by extirpation of the sac there were no deaths, and gangrene followed in less than )> per cent. Vu:. 21.i. -Obliterative cndo-aneurysni- orrhaphy. Fig. 211. — Restorative endo-anciirysm- orrhaphy. Fig. 215. — Reconstructive endo-ancurysmorrhaphy. Endo-axeurysmorril\.phy, introduced by ]\Iatas in 1888. After controlling the circulation, the sac is opened: (1) If a fusiform aneurysm, or a saccular aneurysm with very large mouth (Fig. 207), is found, the sac is obliterated by a series of fine chromic catgut or silk sutures, approximating its walls, and occluding the lumen of the 17 258 SURGERY OF THE BLOOD VASCULAR SYSTEM artery adjacent to the mouth of the sac {Ohliicrative Endo-aiiriiri/stuor- raphy (Fig. 213). (2) If a saccular aneurysm with small mouth is found, it may be possible to suture the margins of the sac mouth with- out occluding the lumen of the i)arent artery (Fig. 214). Orifices of collaterals are then sutured, and the sac walls approximated as before {Restorative Endo-aneurysmorrhaphy) . (3) In rare cases the form of the aneurysm may be such that it will be possible to reconstruct l)y suture a channel to represent the lumen of the parent artery, though little or no evidence of such a channel exists when the sac is opened; a soft catheter may be used as a guide (Fig. 215) (Reconstructive Endo- aneurysmorrhaphy or Aneurysmoplasty .) The methods of ]\Iatas possess over ligation all the advantages of extirpation (less mortality and diminished risk of gangrene) while at the same time they entail less trauma than extir])ation, and in the restorative and reconstructive methods atl'ord the possibility of preserving the circulation through the parent artery; and even if this circulation is preserved only temporarily, gangrene is less likely than if the circidation is occluded immediately as in extirpation. If endo-aneurysmorrhaphy is applied to cases of traumatic aneurysm, this should not be until a firm-walled adventitious sac has formed. Matas in 1910 collected reports of 110 cases of endo-aneurysmorrhaphy (including 67 aneurysms of the lower extremity), with only two deaths (1.8 per cent.) attributable to the operation, and 4 cases of gangrene (3.6 per cent.), 3 of which were chargeable to complications, not to the operation itself. riTAPTKR XL SURGERY OF THE SKIN, BURS.^^], LYMPHATICS, .MLSCLES, TENDONS, AND NERVES. SURGERY OF THE SKIN. Verruca or Wart. — This is a localized hyperplasia of the epidermis, and theoretically may be distinjiuished from a jKipiUoma, which, as noted at j). IIS is a neoplasm. The fa\'orite sites for warts are, the hands, face, scalp, and neck. They iisnally apj)ear to grow spon- taneously, but in a few cases a suspicion of contagion exists; trauma followed by moisture seems a predisposing cause. They show little tendency to enlarge, scarcely ever become malignant, and occasionally disap])ear from no apparent cause. Treatment is sought for dis- figurement, sometimes for pain. Removal is accomplished easily by snipping off the warts with scissors, after spraying with ethyl chloride; the base is then cauterized with silver nitrate. Or by apply- ing a drop or so of fuming nitric acid every few days, the warts will in time shrivel up and fall oft' painlessly. Recurrence is rare after thorough removal. Venereal warts are those growing upon the genitals or around the anus; they are due to irritation from uncleanliness, and have no necessary connection with any venereal disease. Callositas or Tyloma is a dift'use hypertrophic condition of the skin, normally present to a slight degree in the palms and soles, and due to intermittent pressure. It becomes of surgical interest when the hypertrophy is so great as to cause the lesion to approach to that of Claxus or Corn: in this lesion (which frequently develops in the centre of a callosity, or may arise independently, especially on the toes) the intermittent pressure causes a pyramidal shaped up-growth of epithelial cells, which presses upon and finally separates the papilke of the skin, and causes exquisite pain from pressure on the highly sensitive nerve-endings found in this layer. A soft corn is distinguished from a hard corn by the fact that the former is placed where its surface is kept warm and moist, as between the toes; while the hard corn develops on an exposed surface. When of long duration a bursa may be formed beneath the corn, constituting a bunion; this is most often the case over the metatarso-phalangeal articulation of the great toe, often being combined with hallux vahiiis (p. 549). Treatment. — Treatment of corns consists in removal of the cause; in frequent bathing; application of such plasters as will relieve the corn from pressure; use of salicylic acid ointment (5 to 10 per cent.); 260 SURGERY OF THE SKIN Fig. 216. — Hypertrophy of toe-nail, or onychauxis, one year's growth since the nail was last cut off. Episcopal Hospital. paring the surface of the corn (a frequent cause of celluHtis, angeio- leucitis, and sepsis, if carelessly done); and sometimes in formal excision. Cornu Cutaneum or Horn, is a rare affection of the skin, most frequent in old age, and about the face; it may follow the spontaneous evacuation of a wen. Closely analogous to it is the condition of hypertrophy of toe-nails or onychauxis (Fig. 210). Excision is the best treatment. Keratosis Senilis. — See p. 022. Onychia. — Onychia or inflam- mation of the matrix of a nail is classed as simple and malignant. The former, or "run-around," is most frequent in children, starting from a hang-nail, and appearing as a red, swollen, tender semicircle around the base of the nail. Treatment consists in application of anti- septics, with incision as soon as suppuration is suspected. Malignant onychia is a severer form of the disease, occurring in persons much debilitated, and often coming under observation only in the stage of ulceration ("toe-nail ulcer"); any portion of the nail remaining should be removed, the granulations curetted or cauterized, and the part dressed with stimulating ointments. Hygiene should be attended to, and tonics prescribed. Amputation of the phalanx may be necessary if necrosis occurs. Ingrowing Toe-nail. — Ingrowing toe-nail, seen almost exclusively in the great toe, usually is due to ill-fitting shoes, which produce a degree of hallux valgus (p. 549) : in the early stages the form of the nail is unaltered, but the soft parts of the pulp are crowded over on its edge, and injudicious trimming of the nail down' this chink predisposes to ulceration. Later, the edge of the nail becomes folded under, and by pressure on the pulp, aggravates the condition. If palliative treatment be persisted in long enough, a cure usuall\' may be produced by keeping the parts free from pressure, and separating the overhanging skin from the nail either by antiseptic cotton stuffed into the chink, or by drawing the skin aside by adhesi^'e plaster, while the ulcer is treated by desiccating powders after cauterizing its base. The nail should be cut square across the top, and never trimmed down at the sides. If a rapid cure is demanded, it is best to avulse the side of the nail affected (both sides if necessary) by splitting the nail down the centre with strong scissors, and grasping the portion to be removed in forceps. Local anesthesia is sufficient. Tytler (1909) applies a tight ligature around the base of the toe until it is congested, then lightly crushes with forceps the affected half of the nail; in a day or so it becomes soft and bluish, and may be cut away with scissors. As the new nail grows, properly fitting shoes must be worn to prevent recurrence. CARBUNCLE 261 Perforating Ulcer. -Pcrfo rati 11^2; ulcer, usually seen in the sole of the toot or uii(l(T tlu- <;rfat toe, occurs in those ])ast middle life, and is connected with arterio-sclerosis or tro])hi(,' disturbances. It occurs in diabetes, and in locomotor ataxia, and ]>robably is not a specific disease, but merely an evidence of tissue destruction due to malnutrition. It is not attended by much pain, may follow slij^ht injury, frost-bite, etc., and frecjuently originates in a small slouf^h in the centre of a callosity or corn. If untreated, the ulceration steadily progresses, eating through the foot, involving muscles, tendon, and bone; is attended by a stench, and in advanced stages jH'rforates the dorsum of the foot. Under hygienic measures, internal administration of potassium iodide, rest in bed, and active local treatment (cleansing, curetting, etc.), temporary cure sometimes is obtained. Furuncle or Boil. — Furuncle or boil is an infection of a hair follicle or sebaceous gland, confined to the deeper layers of the true skin, usually terminating in suppuration, with the extrusion of a central slough called the core. The usual cause is Staphylococcus aureus, which gains entrance through a minute abrasion, as from a rough edged collar or cufl". Persons with disordered metabolism (diabetes, gout, nephritis, scrofula, eczema, etc.), are especially predisposed to furunculosis. The classical symptoms of inflammation are present — a red, extremely tender and painful swelling, attended by local heat, in the true skin and subcutaneous tissues. Boils vary much in size, but seldom appear over tw^o inches in diameter; they usually are multiple, sometimes appearing in successive crops. Boils usually have a marked tendency to point; those that do not, are called "blind boils." Treatment. — Treatment includes such general hygienic and tonic measures as will prevent a continuance or recurrence of the boils; frequent bathing, with the use of alkalies (sodium carbonate) in the bath and by mouth, is important. By local treatment in the \ev\ early stages it sometimes is possible to abort a boil by pouring pure ichthyol oxev its surface, and making a scab with a film of absorbent cotton. In most cases, however, early incision, besides relieving pain, will accelerate extrusion of the slough, and prevent formation of neighboring boils, which are encouraged by poulticing. After extract- ing the core, pure ichthyol may be poured into the crater of the furuncle, or a drop of carbolic acid may be introduced on a match- stick. The surrounding skin must be kept clean and stimulated with astringent washes. In cases of persistent furunculosis, much benefit has been derived from the administration of autogenous ^'accines. Carbuncle. — Carbuncle may be regarded as an aggravated form of boil (Fig. 217). The infection spreads more wideh^ in the subcutaneous tissues, there is phlegmonous inflammation, and the pus tends to e^'acuate itself through manifold orifices, by following the course of the columnw adiposop (Warren, 1881). Carbuncles are most common on the nucha, and may extend almost from the vertex to the shoulder. 262 SURGERY OF THE SKIN In the old, the diabetic, the subjects of advanced Bri<;ht's disease, etc., it forms a very serious malady, often endanyerinu; life. There is no clear limit to the inflam- mation, which usually is more widespread than is apparent on the surface. Treatment. — Hygienic and constitutional treatment is even of more \alue than in furun- culosis. (1) Small carbuncles should be treated as boils, by early incision which may be crucial if necessary, to facilitate extrusion of the sloughs. (2) Medium-sized carbuncles should be incised as above, and then strapped with adhesive plaster applied concentrically, until only a small orifice is left for the discharge of pus (Fig. 218) ; this strapping, suggested by O'Ferral (1858) and emphasized as particularly valuable by J. Ashhurst, Jr. (1809), acts mechanically by [limiting -^the spread of the phlegmon by erecting an impassable barrier around the base, and forcing the discharge of sloughs through the central Fig. 217. — Carbuncle of neck; duration, two weeks; incised a few days ago; no im- provement. Episcopal Hospital. 1 1 ^^^^B V ^^^H ^^^V "^ % ^'^^^H 1 ^^^^V^;^ ^H HP^ x\ ^^1 \ vM^^^^I ^^^^H F\:f\>:- ^^ 1 Fig. 2 is. — Carbuncle of neck strapped with adhesive plaster. Epis- copal Hospital. Fig. 219. — Carbuncle of u'.'ck after .strap- ping for one week. Only a suj^erncial ulcer remains. Episcopal Hospital. opening; it secures local rest; and also, I believe, creates a certain degree of passive hyperemia in the diseased area, thus increasing the Lcrcs vrijLMus 2(;:5 pliM^ocv tic and (t|)s<>iiic jxjwcrs of the ])ati('iit. The stra|)|)iii^' cliccks almost at once the excessive pain caused l»y tlic carhuncle, and as it nia.\ l)e left in i)lace for several days at a time, consi(leral)ly simplifies the treatment. The gauze which receives the discharf^e throuj:;h the central oj)enin. — Olccianon Inn. sit is, two months' duration; no acute trauma. Epis- copal Hospital. Bursitis. — Bursitis, or inflammation of a bursa, usually follows contusions, and may be acute or chronic. Acute bursitis follows slight continuous, or frequently intermitted trauma, as in the retro- calcaneal bursa {Achillodynia or Albert's disease, 1893), or in the olecranon bursa in those confined to bed, with gouty tendency. Relief of pressure, evaporating lotions, and rest, usually cause subsidence of the inflammation in a few hours. If suppuration occurs, early free incision should be made. Chronic Bur- sitis, which follows slight but continually repeated trauma, may be a sequel of acute bursitis or may be chronic from the start. The bursae most often af- fected are: (1) Prepatellar ("Housemaid's Knee," Fig. 227); (2) Olecranon ("Miner's Elbow," Fig. 228); or (.3) the bursa over the Tuber Ischii ("Weaver's Bottom"). Fig. 229. — InHanimation of bursa beneath tendo iiatella?, bulging on inner side of tendon. Acute onset three days ago, from acute flexion of knee. "Dis- persed" by a blow. Episcopal Hospital. Fig. 230. — Ganglion in bursa of biceps brachii at insertion. Episcojial Hospital. 268 INJURIES AND DISEASES OF THE LYMPHATICS Other bursts sometimes aflFected are: (4) Siil)acromial Bursa (see Periarthritis, \). 4(i6); (5) that beneath the Tendo Patellae (Fig. 229) ; (6) those over the Femoral Condyles (see Ganglion of Popliteal Space, p. 281); (7) Subgluteal Bursa; (8) that over the head of the first metatarsal bone (see Bunion, p. 259, and Hallux Valgus, p. 549); (9) between the tendon of the Biceps and tuberosity of the Radius (Fig. 230). By coagulation of the effused fluid, solid enlargement 9f a bursa may occur. Treatment. — Treatment of chronic bursitis consists in removal of the cause, application of sorbefacient ointments, painting with tincture of iodin, etc.; and, these failing, in tapping and injection of 2 per cent, formalin-glycerin solution or dilute alcohol (never when joint-communication may exist), in incision and drainage (when healing will occur by obliteration of the sac), or in excision which is best in most cases, especially those of long duration with thick sac walls. INJURIES AND DISEASES OF THE LYMPHATICS. Wounds. — Wounds of the lymphatics are of little moment escept when the thoracic duct is injured, as it may be in operations on the neck. If this accident is discovered when the wound is inflicted (by a discharge of milky fluid in the wound — lymiihorrhea) , an attempt should be made to apply a lateral suture. If this is impossible, both ends of the duct should be ligated; and this failing, the wound should be tamponed. If the injury is not discovered at the time of operation, it soon makes itself manifest by a discharge of chyle from the wound, and by rapid and progressive emaciation. There should be no delay in reopening the wound and suturing or ligating the duct. Fredet (1910) collected 58 cases of injury to the thoracic duct, with five deaths. Lymphorrhea. — Lymphorrhea may also occur from wounds of lymphangiectases (p. 2()9), Chylothorax and Chylous Ascites occasionally follow rupture from contusion of the thoracic or abdominal portions of the thoracic duct. Repeated tapping of the thoracic or abdominal fluid has resulted in cure in a few cases. Certain chylous cysts of the mesentery (Chapter XXIII) have a similar origin. Chyluria may result from communica- tion with the urinary tract. Lymphangeitis or Angeioleucitis, inflammation of lymphatic vessels, usually is due to spread of infection from a wound. It is seen most often on the extremities, but I have seen it on the abdomen as a result of omphalitis. There are one or several flame red, irregular streaks running from the site of infection (felon, lacerated woimd, etc.) up to the axillary or inguinal lymph nodes; these streaks coalesce here and there to form broader red bands, and may again separate before reaching their terminus (Plate I, Fig. 1). They are not particularly painful or tender, seldom are palpable, and are redder and less regular L YMF II A NGIECTA SIS 2G9 in tlioir course than veins in cases of plilehitis (p. '2'M)). There is considerable fever, cliills may occur, and lymphadenitis usually co-exists. Treatment consists in cure of the focus of infection; in local rest by si)lints, confinement to bed, etc., and in applications of silver nitrate, dilute iodin, ichthyol, etc., along the course of the inflamed lymphatics. Su])])uration frecpiently occurs in the lymph nodes, but seldom along the lym])h vessels. Lymphadenitis. Lymj)hadenitis, or simply "adenitis," occurs as an incident in cases of lymj)hangeitis, but may also occur when no evidences of superficial lymphangeitis exist. Thus femoral or inguinal adenitis (bubo) frc(|uently follows a blister of the foot, or venereal or other infection of the genitals, when no sign of lymphangeitis can be de- tected (Fig. 231). Epitrochlear or axillary adenitis may arise from a slight abrasion or pimctured wound of the hand which healed before the secondary lesion was noticed. The symptoms are those usual in inflam- mation, and the tender, enlarged lymph nodes are distinctly palpable. Suppuration is not unusual. Secondary invasion by specific microbes (chancroidal, tuberculous) may occur, and somewhat changes the character of the lesion. Any lymphadenitis which assumes a subacute or chronic course is liable to infecton with tubercle bacilli through the blood-stream. This is espe- cially true of cervical adenitis (p. 676). Chancroidal bubo is discussed in Chapter XXVI. Treatment. — Treatment of adenitis im- plies cure of the source of infection; anti- phlogistic applications to the seat of adenitis ; early incision in case of suppuration ; and finally formal exci- sion of the diseased mass of lymph nodes if the resulting sinus fails to close under conservative treatment or if the lymph nodes remain enlarged and tender without the occurrence of suppuration. Lymphangiectasis. — Lymphangiectasis, or dilatation of lymph channels, results from obstruction to the flow of lymph. This may be due to external pressure (as from tumors or cicatrices); to operative removal of the nodes draining the part; or it may be caused by chronic lymphangeitis, causing obliteration of the main lymph vessels, often following repeated attacks of erysipelas, etc. It is much rarer as a consequence of external pressure than is phlebectasis (p. 242), because the lymphatic collateral circulation is much freer. Sometimes it affects the spermatic cord, constituting a lymphatic varicocele. When a distinctly localized swelling is formed, Fig. 231. — Femoral lymph- adenitis; duration, two days; from infected wound of left foot two weeks ago. Episcopal Hospital. 270 INJURIES AND DISEASES OF THE LYMPHATICS it is known as Ii/mphancjeionia; this occurs oftenest as a congenital condition in the face or neck, but may develop in adult life (Fig. 232). It forms a soft fluctuating swelling, covered by healthy skin. Excision is the proper treatment, but if complete extirpation is im- possible, a partial operation entails great risk of lymphorrhagia, with malnutrition; in such cases galvano-puncture may be tried. Macromelia, or giant growth of a part, usually is a lymphangeio- matous condition; one finger, the lips, the tongue, etc., may be affected. Fig. 232. — Lymphangeioma of right foot, aged seventy-five years; duration, Fig. 23.3. — Lymphedema: duration, one seven years. Orthopedic Hospital. year. Episnopal Hospital. Lymphedema, resulting from lymphangiectasis, and consisting of thickening of the subcutaneous tissues from the effused fluid with cellular reaction, occurs principally in the lower extremity (Fig. 233), often associated with chronic ulcer; or in the upper extremity follow- ing ablation of mammary carcinoma and axillary lymphatics (Fig. 744). Ilereditary persistent edema of the legs, w^hich has been studied by Jopson (1898), is believed by Hope and French (1908) to be a vascular neurosis, causing hard edema, which terminates abruptly at the knee or groin, there being no evidence of venous or lymphatic obstruction; but the result is very like lymphedema. If palliati^'e treatment (bandaging, massage, etc.) fails, various operative measures may be undertaken. Excision of wedge-shaped longitudinal strips of the thickened skin and cellular tissues may reduce the bulk of the limb so as to promote ease in locomotion. Lymphangeio plasty (Handley, 1908) consists in inserting long strands of silk in the sub- cutaneous tissues from the hand or foot to the axilla or groin; these act as capillary drains and rapidly reduce the edema. Lanz (1911) drilled holes into the medulla of. the femur and inserted into them strips of fascia lata still attached by one end, thus creating new ii()J)(;kl\'s disease 271 duimu'ls of (Iniinii^c tlironuli i\\v iniirn»\v caxity. Aiii))nt;iti(tii is tlic last resort. Elephantiasis Arabum is a form of lympliedenia duv to ohstniction of lyinpli clianiu'ls hy filaria ffanoNi'nl.s homijii.s, the disease l)einf; called filaridsis. The ])arasite is transferred from patient to patient through a ni()S((iiito as intermediary host. In the ])atient the half grown parasites l()dturp of tendon of extensor longus digitorum to fifth finger; from fall on hand two months ago. Episcopal Hospital. Fig. 247. — Luxation of pero- neal tendons in front of external malleolus of left foot, following paralytic calcaneus. Orthopaedic Hosjjital. Dislocation of Tendons may be pathological or traumatic. The former is more frequent, and is secondary to changes in the contour of the neighboring joints, or to peri-arthritic lesions causing obliter- I'MiONVdllA OR PANARIS 270 atioii ol" llic iiMtural tiTooxc in wliicli tlic tendon lies. In ciises of int'iintilc ]);iriil\sis witli marked caleani'iis detoriiiity the pcroncdl t('ii(lu)is may hv luxated anterior to the external malleolus (Fi^- 247); in i-ases of knock-knee or sim])le relaxation of tissues around the knee- joint, oiifirard lu.vdfloii of the jxifflla may occur; in peri-artiiritis of the shoulder, iiiirdnl dislocation of flic long head of the biceps sometimes is seen, allowinj;- a subluxation forward of the head of the humerus. These deformities may he remedied by ojxTation if disability is marked. Correction of any i)rcdis])()sint:; deformity is the first step. In the case of the patella a suitable knee-caj) may give relief, or the inner portion of the capsule may be pleated on itself, or the point of insertion of the tendo patelhe may })e shifted inward. The capsule of the shoulder may be })leated, and the biceps tendon shortened. Strains of Tendons are of frequent occurrence. Minute extrava- sations occur among the rujjtured fibres, and the tendon is swollen, painful, and tender. Schanz (1005) has called particular attention to traumatic inflanmiation of the tendo Achillis, which often is mistaken for achillodynia (p. 207). Some cases of "trigger finger" (p. 543) may have a similar origin. The treatment is rest during the acute stage, followed by massage. Tenosynovitis or Thecitis is the name given to a form of inflam- mation of tendon sheaths usually caused by rejjeated trauma (strains), in those predisposed to rheumatic conditions. It occurs oftenest in the extensor tendons at the wrist, but is also seen at the ankle, and elsewhere. There is a fine crackling and creaking, appreciable on palpation and sometimes audible, whenever the affected tendons are moved; this is caused by effusion of plastic lymph between the tendon and its sheath. The disease never progresses to the stage of suppuration. Treatment. — Treatment consists in splinting the part and applying ointments of ichthyol or of belladonna and mercury, iodin, etc. Local rest should be insisted on until physical signs have been absent for a week at least; otherwise recurrence is usual. With prompt treatment work generally may be resumed in a few weeks. Tuberculosis of Tendon Sheaths usually is secondary to tuber- culous synovitis or arthritis (p. 477). See also Tuberculous Ganglion, p. 281.' Paronychia or Panaris. — This is a rather vague term, denoting a septic inflammation about the flexor surface of the finger tips (very rarely of the toes). (1) Digital Abscess: The mildest form is an abscess in the pulp of the finger, not involving tendon or bone. Incision in the long axis of the finger evacuates the pus and leads to rapid healing. (2) If the tendon sheath is involved the affection is known as ivhitloiv. In the thumb and fifth finger such inflammation (arising from a pin prick, abrasion, hangnail, run-around (p. 260), etc.), may spread readily to the palmar bursa, with which the sheaths of these tendons usually are continuous, forming jKilmar abscess (Fig. 248). The finger tip becomes extremely painful, tender, throb- 2Rn INJURIES AMD Dh'^EAMm OF TENDONS bing, and swollen. The patient speilcb a sleepless night; poultices bring little relief; inflammation spreads up the tendon sheath, and the whole finger is swollen to two or three times its natural size. Occasionally a whitlow will evacuate itself if ])oulticed long enough (Fig. 241)), but proper treatment consists in very early free incision, Fig. 248. — Palmar abscess ; duration, one week; showing ineffectual incisions made three days ago. Episcopal Hos- pital. Fig. 249. — Whitlow; spontaneous rup- ture; duration, eleven days; untreated. Children's Hospital. into the tendon sheath, and the application of hot moist antiseptic dressings, with suitable splint and sling. At later stages local or general anesthesia may be necessary, with numerous counter-openings and tube drainage, or antiseptic irrigation. After proper incisions, the continuous bath is especially useful. Only when incision is done at the earliest stage can sloughing of the tendon be prevented: the tendon receives its vascular supply through delicate reflections of the synovia, and very slight swelling within the tendon sheath is sufficient to obliterate this circulation. If the tendon sloughs the incision will be Fig. 2.51. — Bilocular ganglion Fig. 250. — Ganglion on extensor surface of wrist (see excised from wrist (see Fig. Fig. 251). Episcopal Hospital. 250). Episcopal Hospital. slow in healing, and a stiff finger will result. Healing of a chronic sinus sometimes may be hastened by dressing it with mercurial ointment. (3) If the periosteum or phalanx is involved, the disease is known as a bone felon, but as the distinction from whitlow rarely can be made before incision, and as treatment is the same, there a A NO LI ON 2X1 Is little use in niakiiifj; a separate sui)(li\isi()ii for felons. Excision or am])utatioii may he necessary it" the i)lialan\ heconies necrotic. Fic. 2.")2. — Tuberculous ganglion of right wrist and palm (hour-glass swelling). Aged forty-two years; duration, five years. Orthoptedie Hos|)ital. Ganglion. — A ganglion is a cyst developed in connection with a tendon sheath, or from the snbsynovial tissues of a joint capsule. Its pathogenesis is not well understood, but probably is a degenerative change (Clarke, 1908). Frequently slight trauma has occurred, but often no such history can be obtained. Ganglia occur oftenest in women, being especially frequent on the extensor surface of the wrist (Fig. 250) ; they are seen less often at the ankle or in the palm of the hand (Fig. 252) and certain bursal enlargements seem clini- cally identical with ganglia (Figs. 230 and 253). Occasionally a ganglion con- tains rice-like bodies, similar to "joint- mice" (p. 478); and sometimes a gan- glion is frankly tuberculous; this is especially apt to be the case in "com- pound ganglia," where the cystic mass is more or less lobulated, possibly as the result of the coalescence of several distinct ganglia. Treatment. — If operative treatment is refused, a small ganglion may be dis- persed by a smart blow with a heavy book, the part being splinted subse- quently for a week or so; recurrences may be expected in over half the cases so treated. Safer and better treatment is aspiration and injection of 2 per cent, formalin glycerin solution or of dilute iodin or alcohol; or formal excision of the ganglion. Tuber- culous ganglia never should be treated by attempts at rupture. Fig. 25.3. — Ganglia in popliteal space; aged eighteen years; dura- tion, over one year. Episcopal Hospital. 282 INJURIES AND DISEASES OF NERVES INJURIES AND DISEASES OF NERVES. Contusion. — Contusion of a nerve produces tingling and perhaps numbness or paralysis in its distribution. A frequent lesion is i)aralysis of the musculo-spiral nerve (less often of the circumflex) from pressure Fig. 254. — Paralysis of musculo-spiral nerve from overlying. during sleep (overlying) — most seen after a debauch, the patient having lain stuporous for many hours (Fig. 254). In other cases the lesion results from a sudden blow or fall, perhaps from sudden abduction of the humerus (Fig. 255). Cridrh-pdlsy, affecting the axil- lary nerves, especially the mus- culo-spiral, is caused by the patient bearing most of his weight on the axilla instead of on his hands, usually because the hand- bars of the crutches are placed too low. Post-anesthetic palsy is due to direct pressure, the arm hav- ing been allowed to hang over the edge of the table (musculo-spiral, ulnar) ; or from pressure on the peroneal nerve below the head of the fibula. This latter form of paralysis may result from im- proper application of a gypsum case. As a rule, the only treat- ment required is rest, followed by massage, electricity, etc. Subcu- taneous rupture is extremely rare, but in compound fractures or similar accidents a nerve may be crushed, complete destruction of the nerve fibres occurring, and only the sheath remaining to connect the bruised ends of the nerve. The signs of loss of function due to such nerve injuries usually are subordinate Fig. 2.5.5. — Paral.wsis of left circumflex nerve with atrophy of deltoid muscle, from sprain of shoulder five months ago. Patient, aged sixty years, fell twenty-seven feet. Episcopal Hospital. STRETCHING OR I.ACER ATION 2S3 to tliosr due to tlie lesions of the iiuisolos, tendons, and bones; l)ut in all snch accidents the surfjeon shonld make tests lor sensation and motion in tli(> i)ait supplied by any nerves which possibly might have been injured. Kesection of the dania<;-ed jjortion, with end-to-end union of the nerve stumps should be done, as described under WOiutd.s of Nrnr.s' (p. 2X1). Dislocation. — Dislocation of a nerve is rare. Occasionally the ulnar nerve slii)s in front of the internal condyle, and causes moderate disability. OptTation generally is necessary to replace such nerves and consists in restoring normal relations and suturing a layer of fascia over the nerve to hold it in place. Stretching or Laceration. — Stretching or laceration of nerves is not iufrccpient as a subcutaneous injury In dislocations or sprains of the shoulder the circumflex, and more rarely the musculo-spiral nerve, may thus be damaged; or rarely the cords of the brachial plexus may be injured. (See also Neuritis, p. 287, and Periarthritis, p. 4()6.) According to Vanden- bossche (1910) it is probable that in most of these latter cases the lesion is in the nerve roots rather than in the brachial plexus. Duval and Guillain (1898) maintained that there were no such clinical entities as paralyses due to lesions of the plexus, only two types existing, radicular and terminal, affecting either the spinal motor roots or the nerve trunks below the plexus. The usual cause of obstetrical palsy (brachial birth palsy) is either direct pressure on the plexus by forceps in delivery (rare), or stretch- ing and laceration from attempts to deliver a shoulder by injudicious traction on the head, or in delivery of the after-coming head. The usual deformity is characteristic (Fig. 256), due to paralysis of the external rotator muscles; the hand is little affected, but supination and flexion of the forearm are imperfect or entirely absent. This corre- sponds to the "upper arm" type (Duchenne-Erb) of brachial paralysis, the lesion being in the outer cord (i. e., fifth and sixth cervical nerves) of the brachial plexus, involving especially the suprascapular and mus- culo-cutaneous nerves (Fig. G36). The " lower arm" type and paralysis of the entire extremity are rare. T. T. Thomas (1914) contends that in most of these cases the nerve injurj^ is secondary to joint damage, and that treatment of the latter is the main indication (see also Congenital Dislocation of the Shoulder, p. 513). In brachial palsy the prog- nosis is not very good, some disability usually persisting throughout Fig. 256.— Braohial birth i>alsy f)f the left arm. in a boy aged seventeen months. Typical posture. Ortho- psedic Hospital. 284 INJURIES AND DISEASES OF NERVES life, no matter what the treatment. Rupture of the nerve sheaths occurs first, and there is more or less laceration of the nerve fibres themselves; intra- and peri-neural hemorrhage occurs, with marked cicatricial changes in the plexus and overlying cervical fascia. Trraf- mctit. After a period of rest, until acute symptoms subside, strychnin should be administered, and efforts made to improve the nutrition of the muscles by massage, electricity, baths, etc. Should no further improvement occur in six months or a year, operation must be con- sidered. A. S. Taylor (1913) urges exploratory operation as soon after birth as the general condition of the infant warrants; but his results do not encourage imitation when it is remembered what great improvement usually follows conservative treatment. After exposing the plexus, it is dissected free from the cicatricial adhesions, irre- trievably damaged segments of nerve tissue are excised, and the stumps reunited or implanted into another nerve as described below (p. 286). Alexinsky (1899) proposed transplanting the peripheral ends of the damaged nerve roots to the opposite side of the neck, and uniting them to the central ends on the other side; a similar operation has been done by Babcock (1907), in a case of anterior poliomyelitis. ^Muscle and tendon transplantation often will give better results than any operations on the nerves. Wounds of Nerves. — These may be an incident in extensive lacerated wounds in\'olving muscles, tendons, and bloodvessels;, or isolated injuries due to stab wounds (Fig. 257). The symptoms are complete loss of func- tion in the distribution of the injured nerve; usually this implies loss of both motion and sensation. If only a per- ipheral sensory nerve is divided, sensation may return in time, even if the ends of the nerve are not sutured; this is due in part to regeneration, and in part to col- lateral circulation, as it were, in surround- ing nerve filaments. But unless the ends I'iG. 2.57. — Paralvsis of pero- p , i i j. • x neai nerve following injury of ot a motor ucrvc are brought mto accu- cauda equina in spinal anes- rate apposition bv SuturC, paralvsis of thesia; seventeen months dura- • -n i ' ^ \ iv " j. tion. Orthopcedic Hospital. motion Will be permanent. Alter suture, the prognosis is uncertain, though if suture is done soon after the accident {primary suture) more or less com- plete recovery is the rule (Figs. 258 and 259); after secondary suture the results are very uncertain (Figs. 260 and 261). Howell (1892) collected 84 cases of primary nerve suture, with 42 per cent, successful results, and 40 per cent, improved; and 80 cases of secondary suture, with 38 per cent, successful, and 50 per cent, improved. Treatment. — The nerve should be exposed, and all damaged tissue excised with a sharp knife. The cicatricial tissue must be excised until the projecting ends of the nerve fibres can be seen in the cross-section. WOUNDS OF NERVES 285 Scissors bruise nervos, and never should he use. — Kccovcij- after primary suture of lausculospiral nerve, for stab wound. Episcopal Hospital. in ophthahnic needles. The sutures, some of which should be of the mattress type, pass directly through the nerve, and are tied just Fiii. 259. — Recovery of function after primary suture of musculospiral nerve for stab wound. Episcopal Hospital. tight enough to approximate without constricting the ends; a few guy sutures should then be applied merely through the nerve sheath, Fig. 260. — Stab wound of median nerve just after operation of secondary suture (three months after injury) ; showing inability to flex wrist, index finger, and thumb (see Fig. 261). (Dr. Harte's case.) Orthopaedic Hospital. to relieve strain, and prevent adhesions of the nerve fibres to surround- ing structures (Fig. 262). If for any reason, the ends of the nerves cannot be made to meet (even by nerve-stretching and flexing neighbor- 286 INJURIES AND DISEASES OF NERVES ing joints), both ends may be implanted into a neighboring nerve trunk (nerpe anastomosis) (Fig. 203), or neuroplasty may be done (Fig. 2(54). A layer of muscle should then be sutured over the nerve, to prevent adhesion to the skin; the wound should be closed; and the limb kept at rest for two or three weeks, when light massage, electro-therapy, etc., Fig. 261. — Recovery of function eight months after secondary suture of median nerve (see Fig. 260). Note power of flexing wrist, index finger, and thumb. (Dr. Harte's case.) Orthopaedic Hospital. Fig. 262. — Nerve suture. Two mattress sutures have been inserted, passing into the nerve substance, and two sutures including only the sheath. may be commenced. Sensation returns long before motion, sometimes within a few days; but hope of motion should not be abandoned \;j5^v; Fig. 263. — Nerve anastomosis. A, the distal Fig. 264. — Neuroplasty. The segment of the wounded nerve is sutured into a proximal segment is split and a flap slit in a neighboring nerve; B, it is implanted in is turned down and sutured to the a wedge-shaped incision. distal segment. NEURITIS 287 for about a year after suture, unless, of course, it can be sliown that the sutures have given way. Under such circumstances the ojxTation may be clone over ajjain. In all cases development of deformity must be prevented by splints, braces, passive motion, etc. Regeneration of sutured nerves dej)ends on the formation of new axones, which some hold develop from proliferation of neurilemma cells in the peripheral segment, while others maintain that in all cases the axones grow out from the central segment, and have to penetrate the distal segment to its various terminations before function is restored. At present the weight of evidence appears to be in favor of those upholding the former view (Ballance and Stewart, 1901), and it is this teaching which justifies us in urging late secondary suture; the axone is there, merely waiting to be joined to the cen- tral segment. So long as the muscles have not become hopelessly degenerated, nerve suture may be successful (after fourteen years, Jacobson). Nerves which have no neurilemma do not regenerate; the nerves of special sense have no neurilemma; nor have the soinal nerves except peripheral to the spinal ganglia. Neuritis. — Neuritis, as the term usually is understood, implies not a reaction to septic infection, but a form of subacute or chronic inflammation due to contusion, to pressure (from cicatrices, callus, exostoses, tumors, etc.), to recurrent trauma {occupation neuritis), to toxic infections (influenza, typhoid fever, etc.), intoxicants (alcohol, lead, etc.), and other less well defined causes. The pathological change is proliferation of the nerve sheath (epineurium, perineurium, and endoneurium), which compresses the nerve fibres (axones), leading to pain, impairment of function, and various trophic -disturbances in the distribution of the affected nerve. The nerve trunk is hj-peremic, perhaps edematous, swollen, and bulbous. Perineural adhesions are frequently present. Symptoms. — The onset may be sudden, after exposure to cold, after violent exertions, or any factor which reduces the patient's vitality. Pain is present in the portion of the nerve diseased, and also shoots along the course of this nerve, usually in a peripheral but sometimes in a central direction. There is tenderness along the course of the nerve, and cutaneous hyperesthesia may be very marked; numbness and a sense of swelling (vaso-motor or trophic disturbances) may be present in the area of distribution. The skin becomes glossy, appears tense and hyperemic; sweating usually is diminished; incurvation or shedding of the nails may occur (Fig. 2(j5); the muscles become atrophic and contractures and reactions of degeneration may develop. The nerve trunks most often affected are those of the brachial plexus, the musculo-spiral, ulnar, and median, and the sciatic. It must be remembered that the neuritis may be only a symptom of another affection (periarthritis of -the shoulder, p. 466; ischemic contracture, p. 540; sacro-iliac or hip-joint disease, p. 536; etc.). 288 INJURIES AND DISEASES OF NERVES Treatment.— Treatment comprises, first and foremost, removal of the cause, whenever this can be discovered (calhis, tumor, cicatrix, etc.). In all cases rest is of utmost importance, and should always be the first step when no obvious cause exists. Counter-irritation sometimes is of value. The patient's general health should be im- proved. Antiseptics may be administered internally, especially the salicylates. Electro-therapeusis, massage, and baking, are suitable only' for the chronic stages, after rest has allayed the acuter symp- toms. In many cases operation is of benefit (Fig. 2fifi), especially neurolysis (dissection of the nerve trunk and even dissociation of its fibres) ; neurectasy (nerve-stretching) is a less certain operation, though aiming to accomplish the same results; neurotomy and neurectomy (except when purely sensory branches are involved) seldom are justi- fiable until other operations have failed. F„, onr. _photo"-niijh showing Fig. 26G.— Photogriiph lundv ciKlit weeks tnS;!^; ;h^n.S^g!>i\>ails as t after operation, to show !^-ven.n^ m result of neuritis of median nerve. finger nails. (bee tig. 2b5.) i^pibcopai January 31, 1907. Episcopal Hos- Hospital, jjital. Neuralgia.— Neuralgia, signifying pain in a nerve for which no pathological lesion can be held accountable, remains an inscrutable problem; and to state, as is often done, that such changes as may be found on microscopical examination of the affected nerve are the result, not the cause of the disease, in no way renders the subject easier to understand. In a word, neuralgia is held to be a tunctional XKLh'ALClA OF Till': l-lFTll CJi'AMAL SKl{VI<: L^S•) neurosis. Many cases of sii])iif)S('(l neuralgia, however, will he foniid oil careful iuvestij^atiou to he due to referred jxi'ni from definite lesions elsewhere. Many are reallx' cases of neuritis. Symptoms. — Its symptoms differ somewhat from those of neuritis; tlie ])ain is equally great, but may come and ^o without api)arent cause; it is more l)urnin<:; and achinji; than sharp and shooting in character; is more influenced hy damj) weather and exposure to cold; and may he unattended with actual changes in the overlying tissues, which are common in neuritis. The tenderness does not extend over the entire course of the afi'ected nerve, but is most intense at certain jioints ("])oints douloureux,") especially where the nerve passes through a foramen (intervertebral, supra-orbital, mental, etc.), or through the deep fa.scia; and pressure on the nerve with the palm of the hand relieves rather than aggravates the pain, though pressure by the finger tip or pointed instrument may bring on an exacerbation of pain. Treatment. — Treatment is much the same as for neuritis, which often can be excluded from the diagnosis only after prolonged rest has failed to give relief. Injections of cocain, alcohol, osmic acid (1 per cent.), and other substances into or around the nerve have been adopted in many cases with varying results (p. 290). Neu- rectasis, neurolysis, and even neurotomy and neurectomy may be done. The forms of neuralgia most important to the surgeon are: Neuralgia of the fifth cranial nerve; Brachial Neuralgia (which has been sufficiently discussed under the heading Neuritis) ; and Sciatic Neuralgia. Neuralgia of the Fifth Cranial Nerve; Tri-Facial Neuralgia or Tic Douloureux. — The pathology of this affection is very little under- stood. Two types are recognized: the minor neuralgia, and the major or epileptiform neuralgia. In the former, which probably is a true neuralgia, there is more or less continuous pain, but it is not exces- sively severe; usually some local or constitutional cause can be found, and on remedying this the neuralgia may stop for a time or permanently. Among such causes are caries of the teeth, sinus diseases, malaria, lead poisoning, chronic nephritis, gout, etc. The major neuralgias, on the contrary, appear to be due to some central lesion which involves the Gasserian ganglion either primarily or by extension from disease of its branches, or possibly by pressure from some intracranial growth. This form of the disease is characterized by progressively severer attacks of neuralgic pain, extending over months or years and affect- ing one or more branches of the fifth cranial nerve, with no discover- able cause. The mandibular and maxillary divisions are affected in most cases; the supra-orbital branch rarely is affected alone. The attacks may be brought on by a draft of air, by touching the side of the face affected, by putting food into the mouth, etc. The skin may become so hyperesthetic that for weeks or months the patient may be unable to wash his face; he may be unable to eat because of 19 290 INJURIES AND DISEASES OF NERVES pain aroused in the lingual and inferior dental nerves; and a state bordering on insanity may ensue finally unless relief is obtained. Treatment. — It shoidd be ascertained whether any local or con- stitutional cause for the neuralgia exists; and such conditions should receive appropriate treatment. If the disease belongs to the major neuralgia type no treatment will be of long avail unless it acts directly on the nerves or ganglion itself. The administration of salicylates, quinin, opium, or other drugs may be useful to allay the pain tem- porarily and thus improve the general health before surgical treat- ment is undertaken. This treatment implies destruction of the nerves or the ganglion, or both. The operations are divided into extracranial or peripheral operations and intracranial operations. Peripheral Operations. — Injection of the nerve trunhs with alcohol (Schlosser, 1907) has entirely superseded injections with osmic acid, as originally advocated by Bennet in 1897. These substances, especially alcohol, destroy the nerve at the point of injection, and though regeneration may take place relief is secured for from six to eighteen months, rarely for longer periods. The longest period of relief secured in my own cases was just short of one year. Patrick, of Chicago, has had large experience with alcohol injections, which he makes into the second and third branches where they emerge from the base of the skull, and into the first branch at the supra-orbital foramen. He does not attempt to make deep injections into the first branch because of danger to other structures in the orbit. He uses this solution : Gni. or c.c. I^ — Cocain muriate 1 Alrohol ... 135 Aquae de-stillata; q. 8 ad 1.5 5 The internal maxillary artery with its branches, including the middle meningeal, is directly in the field of operation and renders deep injec- tions hazardous. But Patrick has had no bad results on this score in 150 cases. The needle is 12 cm. long, 1.75 mm. thick, is not acutely sharp, and is provided with a stylet. To inject the second branch, the needle is inserted at the lower border of the zygoma just in front of the coronoid process of the mandible (0.5 cm. behind a perpendicular let fall from the posterior edge of the orbital pro- cess of the malar bone); while the third division is reached from a point at the lower border of the zygoma 2.5 cm. in front of its anterior root, A tingling sensation in the distribution of the nerve indicates that it has been reached. Usually the nerves must be sought for cautiously b}' inserting the point of the needle in different directions. The foramen rotundum lies about 5 cm., and the foramen ovale about 4 cm. from the surface. About 2 c.c. of the solution are injected into each nerve. "If the operator feels satisfied that the needle is in the nerve (he never knows it)," writes Patrick, "less is enough." No anesthetic is necessary. The injection may be repeated in a few days if the first attempt pro^-es unsuccessful. If bleeding NEURALGIA OF THE FIFTH CRANIAL NERVE 291 occurs tlirou^'li tlic needle tlie stylet should be rej)l;iced and the needle left iit ,sifu until clotting occurs; I punctured a large branch in one case, but no bad effect was noted. Anihion of ihe Peripheral Nerves (Thiersch, 1889) is a more formidable procedure, and usually secures no longer freedom from pain. The nerves arc very slowly avulsed ])y wra])])ing them around a forceps, after adequate exposure. Not more than one complete revolution of the forceps in every half minute should be made. The su})ra-orbital nerve is exposed at the upper margin of the orbit; the superior maxillary at the infra -orbital foramen, whence it may be followed into the antrum of Highmore and along the floor of the orbit; and the inferior dental branch is reached by trephining the angle of the mandible. The lingual nerve may be reached at the same time as the inferior dental by removing some of the ascending ramus of the mandible (G. G. Davis, 1908). These nerves may be avulsed both peripherally and centrally, from this location, but it is well to avulse also the anterior portion of the inferior dental through the mental foramen. The second and third branches of the fifth ner\'e may also be approached extracranially, at the base of the skull, by various routes, involving more or less tedious and delicate operations. These methods were employed chiefly before the general adoption of Thiersch's method, when it was thought necessary to do a formal excision of as much of the nerves as possible; they are now, I believe, very properly abandoned. Intracranial Operations. — Extirpation of the Gasserian ganglion was proposed by INIears, of Philadelphia, in 1884, and first performed by E. Rose in 1890. Rose employed the pterygoid route, trephining the base of the skull. Hartley, of New York, and Krause, of Altoona, independently in 1892 proposed the temporal route, and most surgeons now employ some modification of the Hartley-Krause method. Owing to the difficulty of removing the entire ganglion, from the presence of adhesions and its intimate relation with the cavernous sinus, sixth nerve, etc., many of the earlier operations were only partial excisions, and well merited the description "bloody, difiicult, and dangerous," which is still applied to them by Da Costa. To simplify the operation, Abbe (1903), merely divided the second and third branches before they left the skull, and interposed a strip of rubber tissue to prevent their reunion. Spiller (1901) by a happy inspiration suggested to Frazier that section of the sensory root of the ganglion would amount to a physiological extirpation of it, since this root, which is devoid of neurilemma, could not on that account regenerate. This operation, as pointed out by Frazier, is easier, is attended by less hemorrhage, does not expose the cavernous sinus or sixth nerve to injury, leaves the motor root (and consequently the muscles of mastication) intact, and, finally, involves a diminished risk of keratitis, which was so prone to follow removal of the entire ganglion. 292 I XJ CRIES AND DISEASES OF NERVES Frazier-Spiller Operation. — A flap of soft parts is turned down, care being exercised not to injure the upper branches of the facial nerve. A sufficient amount of bone is then removed from the temporal fossa, with trephine and rongeur, and the dura is raised from the base of the skull. Frazier always ligates and divides the middle meningeal artery, as it leaves the foramen spinosum. The bura covering the mandibular division of the nerve is then incised, and the ganglion exposed. If the motor root is seen, it should be separated from the sensory; this latter is then divided or avulsed. The brain is then allowed to fall back on the base of the skull, and the soft parts are closed with drainage. The mortality following the operation in the hands of skilled operators is less than 4 per cent. The chief dangers are shock, hemorrhage, and infection. After-care. — For weeks or months after operation the eye of the same side should be most carefully protected by a shield (an automo- bile goggle is suggested by Frazier), as destruction of its protecting nerve supply renders the cornea exceedingly prone to trauma and infection, and many patients have lost their sight from this cause. Sciatic Neuralgia or Sciatica. — This is not regarded as so frequent a lesion now as formerly, since it has been shown that in most cases the disease really is a neuritis, or is merely referred pain due to pelvic (Fig. 582) or hip disorders. If no cause of referred pain can be dis- covered, and if rest, antirheumatic drugs, counter-irritation (blistering, cauterization), and other palliative methods are ineffectual, the surgeon may be tempted to adopt operative measures, on the theory that the affection really is a neuritis, from infection or trauma, with perineural adhesions. Xeuredasis may be secured without incision by forcibly flexing the thigh on the abdomen with the knee fully extended (the patient being anesthetized) ; or by exposing the sciatic nerve below the gluteus maximus, either on the inner or outer side of the biceps muscle, and stretching it over the finger both centrally and peripherally; the patient lying on his face it is safe usually to employ traction sufficient just to raise the limb from the table. Xcurolysis is a safer and more certain operation; the sheath is opened and the nerve fibres separated from it and from each other for a distance of several inches; Pers (1908) has adopted this method 47 times, and among 42 uncompli- cated cases there were only three recurrences. In many cases the adhesions extend up into the sciatic notch, and the completion of the operation may be difficult. Best exposure is secured by splitting the fibres of the gluteus maximus at the level of the great sacrosciatic foramen. Tic Convulsif or Spasmodic Tic is a form of neuralgia, usually not painful, characterized by constant and often severe twitching in the muscles supplied by the aft'ected nerves. In the neck, which is its most frequent seat, it produces spasmodic torticollis; it also occurs in the face, the shoulder, and very rarely in other parts of the body. ^Myotomy, neurectasis, neurotomy, and neurectomy have been TUMORS OF NEIiVES 293 employed, but tlie disease always recurs in other muscles, no matter how wide the primary nerve excision may have l)een. Some neurolo- gists go so far as to maintain that even were the cortical centres governing the region to be excised, neighboring centres would take on diseased action. At present cure of the disease seems hojx'less by operation, tiiough the temporary imjjrovement usually secured is not to be despised. Tumors of Nerves. — Fibrous out-growths sometimes occur on the ends of nerves in an ami)utation stump ("amputation neuromas"), apparently due to attenii)ts at regeneration: the nerve fibres turn back upon themselves, being unable to make headway forward, and form painful bulbous masses, which usually have a strong tendency to recur if excised, or even after formal re-amputation. Such growths are rare except where the amputation was a l)ungling ()j)eration. jMultiple tumors occasionally are formed along nerve trunks or at the ter- minations of nerve fibrils in the skin. This disease is variously known as multiple neuro-fihromatosis (when confined to nerve trunks); von Recklinghausen's disease (1881) or inoUusciim fihrusum (when occurring in the skin); and Uanhenneurom or ylexijorm neuroma, which occurs in the form of a circumscribed thickening of the skin, due to out-growth of nerve fibrils — a condition most often found in the neck or scalp, sometimes pigmented, and usually congenital. Da Costa (1910) compares the condition of nerves in a plexiform neuroma to that of the arteries in a cirsoid aneurysm. This disease, in its various forms, usually has been considered a form of difi'use fibromatosis, blastomatoid in character; but in the second edition of his Pathology (1910) Adami returns to v. Recklinghausen's original theory, and to that of Klebs (1889), which lately has received support from other observers, that these growths originate in the nerve fibrils themselves, and should be classed as Neurinomas. Excision of one or several of the multiple growths may be required for pain or deformity: those on the nerves sometimes may be shelled out with- out destroying the continuity of the nerve trunk. The "plexiform neuroma" sometimes recurs after removal; sarcomatous changes may occur, though they are not very frequent. CHAPTER XII.5 P^RACTURES. The study of fractures is one of the most important subjects which can engage a surgeon's attention; they are injuries which occur constantly, in all classes of life, and under all circumstances. Even a general practitioner cannot avoid having a number of cases under his care every year; and no cases contribute as much to the fame or discredit of the man who treats them. And while it is well recog- nized that the most skilful and assiduous treatment cannot in all cases succeed in giving the patient a useful and comely limb, yet it is sadly true that many of the bad results con- stantly seen are due to sheer ignorance and neglect on the part of the practitioner. Classification. — Fracture of a bone may be complete or incom- ylete. The latter form {green- stick fracture) occurs almost exclusively in young children, the bone fibres in the line of extension (convexity) being com- pletely ruptured, while those in the line of flexion (concavity) maintain their continuitv (Fig. 2()7). Fractures may be subcuta- neous {simple) or open {com- jjound), the latter term implying that the seat of fracture com- municates with the external air through a wound of the soft parts. Comminuted fractures are those with more than two fragments, the lines of fracture intercommunicating (Fig. 208). They are to be dis- tinguished from double {triple, quadruple, etc.) fractures in w^hich two (or more) separate and distinct breaks are present in the same bone. Fig. 267.- — Green-stick fracture of radius and ulna with extreme deformity. Penn- sylvania Ho.spital. CI.ASSIFICATION 21)-) M ullij)!)' fiuK tiirr ( Fi<;-. 2(»U) is a term wliicli should he reserved for eases with hreaks in more than one hone, the hones aU'eeted not heing parallel (liUe the rihs, those of the forearm, the le^', hand, ete.). Complindcd fractures are those attended l)y some other serious injury of ihc sumc part, as rupture of the main hhxxhessels, erushin^ of nerves, disloeation of neighbor- ing joint, etc. A fracture of the lower end of tlie femur may be com- plicated by a fracture of the skull, or by a stab wound of the hmg, but such a fracture is not a "compli- cated fracture of the femur" un- less the popliteal artery is ruptured, the knee-joint dislocated, or some other serious injury exists in the immediate neigliborhood of the fracture. Fio. 268. — Comminuted fracture of tibia and fibula, a few hours after in- jury. Episcopal Hospital. Fig. 269. — Multiple fracture of upper extremity. Episcopal Hospital. Direction.— Fractures are further classified as longitudinal, trans- verse, oblique, spiral, etc. These terms are self-explanatory^ and ^are illustrated in the accompanying skiagraphs (Figs. 270, 271, 272). Transverse fractures are more frequent in cancellous bone, and when 296 FRACTURES occurring in the shafts of long bones usually are due to direct violence; whereas ol)lique and spiral fractures, seen almost exclusively in the shafts of the long bones, generally are due to a twisting force trans- mitted from a distance; and longitudinal fractures, freciuently extend- ing into a joint, usually are caused by a splitting action. A depressed fracture is one seen almost exclusively in the skull, in which the fragments are displaced b>' the vulnerating force below the level of the surrounding bone. An impacted fracture is one in which one fragment is driven into the other, and remains fixed (Fig. 306). Subperios- teal fracture is one in which the })eriosteum wholly or in great part remains unrup- tured. Epiphyseal Separations. — The epiphyses, or articular ex- tremities of the long bones, may be detached from the shafts (diaphyses) by separa- tion along the epiphyseal line until the age when ossifica- tion is complete in the car- tilage which unites epiphysis with diaphysis. The injury is most common at the lower ends of the humerus, radius, and femur; it is seen also, but more rarely, at the upper ends of the humerus, femur, and tibia, and at the lower end of the tibia. The injury, in all its aspects, so closely resembles a fracture, as to be considered by common consent along with such in- juries. Mechanism. — Bones may be broken in four different w^ays: (1) by torsion; (2) by flexion; (3) by distraction, and (4) by compression. For a bone to be broken by torsion, it is necessary for one of its ends to be free, while the other is fixed; the injury always is indirect, and the line of frac- ture usually oblique. When a bone is broken by flexion, the force may be either direct or indirect. All fractures by distraction are due to indirect violence, and practically all produced by compression result from direct violence. Fig. 270. — Longitudinal (splitting) fracture of tibia and fibula (involving knee-joint). Age, forty years. Episcopal Hospital. CA USES 2'.»7 Causes of Fracture. Predisposing Causes. — Tlicsr arise citluT from the (oiulitioii of the patient or that of the l)oiie afl'eeted. JJoiies of the a(j('(l are more Hable to fracture, heeause more brittle, than those of yoimg i)er.sons; but as tlie hitter lead more active lives, and are more exposed to exciting causes, the number of fractures actually occurriufj in the aj^ed is less than in the young. Likewise the male .sv.r, from its greater ex])osure, is more lia})le to fracture than the female. Certain r//,s7Y/.sT.s- of hones render them more liable to be Fig. 271. — Transverse serrated fracture of humerus. Episcopal Hospital. Fig. 272. — Oblique and spiral frac- ture of femur. Age three years. Episcopal Hospital. broken, especially osteopsathyrosis and malignant growths. The situation of a bone may predispose it to fracture, the clavicle being more often broken than the scapula, the lower than the upper jaw', etc.; and the function of a bone has a predisposing influence, the bones of the extremities being broken more often than those of the trunk. Exciting Causes. — Fractures may occur at the point of impact, from direct violence (gunshot, cart wheel, falling brick, etc.); or may be due to transmitted force {indirect violence), as fracture of the elbow from falls on the hand. 298 FRACTURES Fracture by mvscular action usually is a variety of fracture from indirect violence, one end of a long bone being twisted violently by the muscles attached to it, and being wrenched loose, as it were, from the other end, which opposes its inertia to the sudden muscular impulse; this is the explanation of fractures of the humeral shaft from throwing a ball (Ashhurst, 1905). Muscular action may tear off an apophysis (coracoid process, greater tuberosity of humerus, anterior superior iliac spine, etc.), or may break the patella or olecranon by sudden flexion over their neighboring condyles, as an over-bent lever. S prain fractiire (Callender, 1870) is due to separation of a ligament from its point of insertion, with detachment of a small shell of bone. Spontaneous or Pathological Fractures are those due to preexisting bone disease, where trauma is minimal, as in fragilitas ossium, secondary carcinoma of bone, etc. Symptoms of Fractures. — In addition to a history of injury, which exists in all cases except some pathological fractures, there are both symptoms and physical signs by which a diagnosis of fracture can be made clinically, with very few exceptions; in such exceptional cases the use of the or-ray nearly invariably will reveal the true nature of the lesion. Pain and Tenderness. — These are present in practically every case and are by no means proportionate to the apparent degree of injury, some very severe compound comminuted fractures causing the patient less discomfort than a single subcutaneous break. When no other physical signs are present, the surgeon should always suspect a fracture when there exists persistent localized tenderness of a bone, following injury; such a fracture may be subperiosteal or impacted, and the surgeon should treat such a case as one of fracture until the incorrect- ness of his diagnosis has been proved. Swelling, Ecchymosis, etc., are present to some degree in nearly all cases of fracture (Fig. 273), owing to coincident injury of the soft parts; but they have no special significance. Abrasion over the seat of fracture usually shows that the break is due to direct violence. Deformity or Displacement. — This is one of the most constant and valuable signs of fracture. It may be due either (1) to the fracturing force, or may occur subsequently (2) from muscular action; both these factors may be operative; or finally it may be caused simply (3) by the weight of the limb. 1 . Deformity from the fracturing force is seen best in impacted and in depressed fractures. In fractures with great displacement other factors as well usually are at work. 2. Deformity from muscidar action is seen especially in the long bones of the extremities, and occurs most markedly when the fracture is close above or below the attachment of powerful muscles — as above or below the insertion of the deltoid, below the insertion of the iliopsoas tendon, above the origin of the gastrocnemius, etc. In fractures of the patella and olecranon it is almost the only cause of deformity. It is responsible both for the shortening, and for the angular deformity, as well as for many cases of rotatory displacement. SYMPTOMS 299 Deforniity from nuiscular action is dopenflent in part on the natural fcn serious constriction, pcrliaps rcsnltinj^ in ' to displacement, the fragments (in the case of small bones) should be sutured with heavy cliromic catgut, which will not be absorbed until union is so firm as to prevent sul)seqiient displacement; in the case of the femur and in oblique fracture of the til)ia it is safer to use a metal plate, since maintenance Fig. 280.— Hamilton's drill. Fig. 281. — Fragments united by two wire sutures, inserted in different planes. of reduction bv external dressings alone usually is difficult. The form of plates \ised by Lane (1905) probably is best: these are of steel, of various sizes, and are applied to the bone without displacmg the periosteum. About three screws are inserted in each fragment ; the holes are bored by a suitable drill (Fig. 280) or dental engine, should extend into the medulla and should be slightly less in diameter than the screws; the screws should have round heads, should have the tliread carried up to their heads and should be just long enough to enter the medullary cavity. The use of plates has almost super- seded wire sutures "in large bones (femur, tibia, humerus, lower half of radius), but in smaller bones (clavicle, ulna, fibula) wire sutures are efficient and may be more easily applied; it is best to use two 312 FRACTURES sutures, at right angles to each other (Fig. 2<>!)). Tn all fractures of the shaft the diagnosis is easily mad(\ and reduction is not difficult to secure nor to maintain if an efficient dressing is applied. That which I have used with perfect satisfaction is shown in the accompanying illus- trations. A primary roller is applied up to the elbow; the arm is surrounded by raw cotton; three coaptation splints of binder's-board are adjusted around the arm, one anteriorly, one posteriorly, and one externally (Fig. 310), and are secured by continuing the bandage up to the axilla; over this a shoulder-cap is next adjusted (Fig. 311), and fixed by a spica of the shoulder (Fig. 312); the arm is finally bandaged to the chest and a wrist sling applied leaving the elbow unsup- ported to give extension to the seat of fracture (Fig. 313). In rare cases with overlapping of very oblique fractures, weight extension can be ap- plied as an ambulatory dress- ing (F^ig. 314). If the fracture is in the lower third of the humerus an anterior angular splint (Fig. 315) may be used, either alone, or in addition to the use of a shoulder-cap; but in fractures above this region any attempt to im- mobilize the elbow will result in transferring every motion of the forearm to the seat of fracture in the humerus, and delayed union frequently will result. 22 Fig. 311. — Dressing for fracture of shaft of humerus: shoulder-cap applied. Episcopal Hospital. 338 FRACTURES Fractures of the Lower End of the Humerus. — These are much more frequent in children than in adults. The usual cause in children Fig. .312. — Dressing for fracture of shaft of humerus, shoukler-cap secured by spica bandage of shoulder. Episcopal Hospital. Fig. .31.3. — Dressing for fracture of shaft of humerus completed and wrist sling applied. Episcopal Hospital. is a fall on the outstretched hand; in adults such an accident is more apt to cause dislocation if the lesion occurs at the elbow. Direct Fi"G. 314. — Weight extension for frac- ture of shaft of humerus. Episcopal Hospital. Fig. 31-5. — Anterior angular splint applied to elbow. Episcopal Hospital. injury, often resulting in compound or comminuted fractures, is a more frequent cause of elbow fractures in adults. There are several FRACTURES OF THE ICLBOW 339 distinct types of Fracturt' lioro, which may he conveniently c thus (PV •^••'): 1. Sni)racoii(lyIar I'Vactures ^ 2. Diacondyhir Fractures ^ These are tlie most frequent v 3. External Condyle J 4. Epiphyseal Sei)aration. 5. Internal Condyle. (). IntcTcondylar. T or Y. 7. Ei)itrochlea. The lower epiphysis of the humerus is de\elopcd from a of centres, and is l)est studied in a series of skia,kiagrai)h ot epiphyseal , • i c -i ' separation of left humerus. rarely IS present ; but failure to Fi( FRACTURES OF THE El. HOW 343 recognize tlic lesion may l)e disastrous. The diagnosis is based on a his- tory of injury, on indistinct, nuifflcd crepitus, extreme pain on forced extension and persistent hx-aiized tenderness in the flexure of theelhow. Fk;. 323. — .Skiagraph of fracture of internal condyle of humerus. Episcopal Hospital. 5. Fractures of the Internal Condyle. — These are rare in children, but being caused usually by direct violence (falls on the acutely flexed elbow) are relatively more frequent in adults. The usual line of fracture is shown in Fig. 323. The disability is extreme, the support of the ulna being destroyed: the forearm falls against the side, causing loss of the carrying angle, and the internal condyle may be moved antero-posteriorly on the shaft. 6. Intercondylar Fractures are very rare, especially in children. They are caused by great violence, almost always direct, the ulna being driven up between the condyles and separating them from each other and from the shaft (Madelung), resulting in a Y-fracture; or the diaphysis splitting into halves the fragment due to a supracondylar fracture (Gurlt, 1862), resulting in a T-fracture. The diagnosis rests on the independent mobility of the condyles on each other and on the shaft. 344 FRACTUEES 7. Fractures of the Ejntrochlea (Fig. 324) often are epiphyseal sepa- rations of this centre, as it does not unite witli the diaphysis until the Fig. .324. — Skiagraph of fracture of epitrochlea of humerus. Episcopal Hospital. eighteenth year. The injury usually is due to muscular or ligament- ous action, and is a not unusual accompaniment of posterior dislocation of the elbow. Fig. 325. — Fracture of capitellum of humerus, from fall on elbow. Age thirtj'-eight years. Patient under care of Dr. Jopson in University Hospital. Fragment replaced by arthrotomy. Excellent result. Of other rarer fractures of the lower end of the humerus, those of the capitellum (Fig.' 325) are of most importance; the fragment usually FRACTURES OF THE ELBOW 345 is displaced into tlic Ixnid of the elbow, and seldom can be replaced without incision. Treatment of Fractures- of the Lower End of the IIunieruff.—A^ these fractures are all close to the joint, and many of them wholly or in part intra-articular, it is extremely important to secure early and aecurat(> reduction of the frat^ments, in order to lessen the amount of callus formed, and thus i)ermit restoration of perfect function. Intelligent man(ruvres of reduction can l)e undertaken only after a correct diagnosis has been made, and 1 have dwelt upon the indi- vidual lesions so fully not because their treatment is materially ditfcrent, but because accurate reduction must be secured at the earliest possible moment; only in this way can surgeons hope to remove the oi)pr()l)rium which has long attached to these injuries and which 1 believe is quite unnecessary. a - Fig. 32G. — Diagram of carrying angle. (After Potter.) Fig. 327. — Patient shownng normal carrying-angle on right and gunstock deformity on left. Children's Hospital. Supracondylar fractures form the large proportion of these injuries, and I shall discuss the treatment of this variety at greatest length. The muscles arising from the condyles of the humerus are the only muscles attached to the fragment, and they tend to keep it flexed on the forearm. Motion transmitted from the forearm takes place between the fragment and the shaft of the humerus, not in the elbow- joint. The fragment usually is displaced posteriorly. All these considerations, as well as clinical experience, teach that it is better to dress these injuries with the elbow flexed. The fracture is reduced, by hyperextension of the elbow to relax the triceps, then by extension 346 FRACTURES and counter-extension to bring the fragment forward into its normal relation with the shaft. It is kept reduced by hyperflexion of the elbow (flexion as acute as possible), thus bringing the insertion of the triceps anterior to the humerus, and making this nuiscle act as a sling in holding the fragment in place. In order to preserve the "carrying angle," which is formed by an equal obliquity of the articular surfaces of the humerus and the bones of the forearm (Fig. 326), it is extremely important to flex the forearm upon the arm directly in the sagittal plane, and to keep it in that position, thus avoiding internal rotation of the lower fragment. When there is Fig. 328. — Patient showing cubitus valgus after recovery from fracture of internal condyle. Episcopal Hospital. loss of the "carrying-angle" (cubitus varus, Fig. 327) the forearm falls to the outer side of the arm when the elbow is hyperflexed. Increase of the "carrying angle" (cubitus valgus) is a less conspicuous and much less disabling deformity (Fig. 32S). Other fractures of the lower end of the humerus must all be reduced accurately by suitable manipulations, which cannot be described at length here. All may be kept reduced by dressing the elbow in hyperflexion. The method in which this is to be done is sufficiently indicated in the accompanying illustrations: the arm and forearm act as splints to each other, and when they are bound to each other they may be rotated inward as one bone, and the hand slung around the neck (Figs. 329, 330, 331). The elbow is dressed rnACTURKS OF THE KLIiOW 347 Fig. 329. — Dressing to maintain elbow in hyi)rrflexion, first static. Ei)iscopal Hospital. Fig. 330. — Dressing to maintain elbow Fig. 331. — Dressing to maintain elbow in hyperflexion, second stage. Episcopal. in hyperflexion, completed. Episcopal Hospital. Hospital. 348 FRACTURES about twice weekly, the hyperflexion being reduced at each dressing only enough to permit washing the flexure of the elbow, and re-inser- tion of a fold of lint. At the end of the second week the elbow may be dressed in less acute flexion, and at the end of four weeks may be carried in a sling for a week or ten days. No massage or passive motion is necessary to restore function if accurate reduction has been secured; but full extension may not be secured for several months. Ulna. — Fractures of this bone are caused mostly by direct violence. Fractiires of the olecranon, however, may occur from muscular action in sudden flexion, or as a "compression" fracture in hyperextension of the elbow; unless the aponeurotic insertion of the triceps is torn widely there is not much separation, but mobility and crepitus usually are distinct. In simple fractures operation rarely is indicated, as by strap})ing the fragment on to an obtuse angled splint (Fig. 332) reduction usually is easy; even if accurate reduction is not secured Fig. 332. — Dressing fracture of olecranon on anterior obtuse angled splint. Padding omitted to show splint better. Episcopal Hospital. at the first attempt, it is remarkable how much imp^o^•ement in position is obtained in a few days. This is one of the few fractures which prove an exception to the general rule that prompt reduction is necessary for recovery of good function. In compound fractures, operation is preferable (Figs. 333 and 334). Separation of the olecranon epiphysis, which appears first in a skiagraph from ten to eleven years, is a rare injury, requiring the same treatment as fracture. Fracture of the coronoid process is a rare accompaniment of posterior dis- location of the elbow, and is to be suspected when it is diflScult to maintain reduction of this lesion. The fragment, which is partly intra-articular, and which has the brachialis anticus attached only to its base, seldom is much displaced. Treatment consists in dressing the elbow in hyperflexion for a couple of weeks, and then allowing gradual extension. Fractures of the shaft of the ulna are very dis- abling, as the ulna forms the main part of the elbow-joint, and through the interosseous ligament supports the radius and hand. Patients FRACTURES OF THE ULNA 349 wltli fracture of tlu> ulna rarely can hold the forearm out for an examination without sui)i)ort from the other hand. In the ui)i)er part of the shaft the displacement often is backward, owing to the Fig. 333. — Skiagraph of compound fracture of olecranon. Treated by operation. (See Fig. 334.) Episcopal Hospital. pull of the triceps (Fig. 33(3) ; but when the trauma has been great, the ulna may be displaced anteriorly, the continuation of the force causing forward dislocation of the head of the radius (Fig. 406). In the lower part of the shaft, the pronator quadratus draws the lower Fig. 334. — Skiagraph of compound fracture of olecranon, after suture of aponeurosis of triceps with chromic catgut. Age twenty-five years. Episcopal Hospital. fragment against the radius, producing a deformity very difficult to overcome, though sometimes extreme abduction of the hand, by the use of a reverse Bond splint (one made for the other hand), may 350 FRACTURES succeed (Skillern, 1910). Green-dick fractures of the uhin are frcHjuent, but these, as well as complete breaks of the middle and lower thirds, are frequently accompanied by fracture of the radius. Fracture of the styloid process of the ulna often accompanies fractures of the lower end of the radius. Owing to the subcutaneous position of the ulna the diagnosis of these various fractures presents few difficulties; and all may be treated by immobilizing the fore- arm on a straight splint, with pads so adjusted as to o\ercome the tendency to displacement. Radius. — Fractures of the head of the radius usually are caused by a fall on the over-extended ]:)alm, the force transmitted through the radius making it impinge with great force on the external condyle, and splitting the head of the radius into two or more parts (Fig. 335). The symptoms are persistent localized pain and tenderness, indistinct crepitus on rotation, but rarely appreciable mobility or displace- ment. A skiagraph usually is necessary for confirmation, but unless several are taken in differ- ent planes, the line of fracture may not be visible. If there is a loose fragment it is better to excise it, as non-union is frequent. In most cases, however, it is sufficient to immobilize the fore- arm for about four weeks in fnll supination on an anterior angular splint (Fig. 315). Fractures of the neck of the radius result from much the same causes as those of its head, but may accompany fractures of the olecranon from a fall on the flexed forearm; or may be accom- panied by a fracture of the shaft of the ulna (Fig. 336). These fractures are apt to be impacted, and it is not desirable to disturb the impaction lest non-union result, the upper fragment being so small as to be uncontrollable. The forearm should be dressed in full supination. Fractures of the shaft of the radius are unusual except when accompanied by fracture of the ulna. If the fracture is above the insertion of the pronator radii teres, this muscle will pronate the lower fragment while the upper will be supinated and flexed by the biceps; to reduce the deformity the forearm should be dressed in full Fig. 335. — Fracture of head of radius. Age twenty-six years. Episcopal Hospital. FRAl'TURI'JS OF THE RADIUS 351 supination (Lonsdale, KS;JS), on an anterior splint, with the elhow flexed. If the fraeture oecurs below the insertion of the pronator radii teres this nuiscle will keep the ui)per fragment senii-pronated, and the lower fragment should he brought into that position before the splint is applied, and so dressed. Fig. 330. -Fracture of neck of radius complicating fracture of upi)er half of ulna. Episcopal Hospital. Fmriurcs of the Lower End of the Radius.— The typical^ fracture in this region, one of the most frequent in the entire body, is known by the name of Colles (1814). Colles's Fracture results almost invari- ably from a fall on the over-extended palm, and the break occurs about 1 or 2 cm. above the wrist-joint; the lower fragment is dis- placed toward the extensor surface, often being impacted into the posterior surface of the shaft, the lower end of which protrudes Fig. 337. — Colles's fracture of radius, showing silver-fork deformity; recent accident in patient of sixteen years. Episcopal Hospital. beneath the flexor tendons. This typical displacement is known as the "silver-fork deformity," and Fig. 337 shows that it is well merited; often, how^ever, deformity is much less evident. In addition to the antero-posterior displacement (Fig. 338), there usually is moderate radial deviation of the hand, rendering the head of the ulna promi- nent (Fig. 339). A fracture of the ulnar styloid is a frequent accompaniment. Crepitus and mobility seldom are present, and the 352 FRACTURES diagnosis usually is made from the deformity and localized pain and tenderness; but even in cases without visible deformity the lesion should be suspected from the 'nature of the injury. If un- recognized as a recent injury the deformity may become much more evident in the next twenty-four hours, and the patient and the surgeon whom he consults then, are apt to blame one who failed to recognize a fracture the dav before. Treatment consists in reduction as soon Fig. 33S. — Skiagraph (lateral view) of unreduced CoUes's fracture of radius, slight silver-fork deform- i'.y; duration three weeks. (See Fig. 339.) Episcopal Hospital Fig. 339. — Skiagraph (antero-posterior view) of unreduced Collcs's radial fracture of radius, with displacement of lower fragment, and fracture of the styloid process of the ulna. (See Fig. 338.) Episcopal Hospital. as possible after the injury (Fig. 340) : this is accomplished by hyperex- tension and forced adduction of the lower fragment (Fig. 341), followed by direct pressure forward on it, with counter-pressure backward on the lower end of the upper fragment. If impaction is very firm, an anesthetic maybe required. Usually more force is necessary even in cases of slight impaction than the inexperienced surgeon expects; and though failure to secure accurate reduction may not materially interfere with use of the hand, some deformity will remain, and FRACTURES OF THE RADIUS 353 ill many cases tlir hand is iKTnianently weakoncd. Any drossinj; which will hold the l"ra<,Mncnts in i)hK'c may then he appHed, the Fig. 340. — Skiagraph of recent Colles's fracture of radius and fracture of styloid process of ulna, after reduction. Episcopal Hospital. forearm being in semi-pronation or full supination, never in complete pronation. Supination is the movement which is most difficult Fig. .341. — Reduction of Colles's fracture, of left radius. Episcopal Hospital. to regain, and if the hand is dressed in pronation, it may never be regained; whereas if the fracture is put up in full supination, all 354 FRACTURES subsequent activities of the hand will be such as to encourage return of pronation. In cases where no tendency exists for recurrence of dis- placement, a straight posterior splint (Tig. 342 j makes a comfortable Fig. 34:2. — -Posterior splint for Colles's fracture. Padding omitted for photograph. Episcopal Hospital. dressing; for the first week this should extend to the proximal inter- phalangeal joints, but may then be shortened to the metacarpo- phalangeal articulation^. In cases where reduction is difficult to Fig. .343. — Bond's splint. maintain. I prefer to use a Bond splint CFig. 343), on the flexor surface, with two compresses, one on the dorsal surface over the lower fragment, and the other on the flexor, to fill up the natural concavity Fig. 344. — Bond splint for Colles's fracture. Padding omitted from splint, and leather guard removed to show compresses; note their form and position. Episcopal Hospital. of the forearm above the wrist, and to retain the upper fragment in proper position (Fig. 344). Splint support should be continued for four weeks. FRACTURES OF THE FOREARM 355 Other FraHiiirs of the Lower End of the, Radius. — Barton's Fracture (1838) is tlu' name ijivcn to (letuchineiit of the dorsal portion of tlie articular surfacr of the radius; diagnosis without a skiaj^^raph is difficult. Reverfied Colle.s's Fracture, in which the lower fragment is displaced toward the flexor surface, was described in 1865 by Cal- lender; the displacement was named "gardener's spade deformitx" by Roberts (1897). Chauffeur's Fracture, so named because often received while "cranking" an automobile, may be of various types, the most frequent of which is one splitting off the outer surface of the articular surface of the radius through the base of the styloid process (Fig. 345). Separation of the lower radial epiphysis (Fig. 28(ij can be certainly distinguished from Colles's fracture only by radiograpli>-. All these lesions should be treated by reduction of deformity, when present, and immobilization for about four weeks. Fig. .34.5. — "Chauffeur's fracture" of lower end of radius, caused by kick of handle while cranking. Line of fracture emphasized in retouching skiagraph. Orthopaedic Hospital. Both Bones of the Forearm. — These fractures are frequent, either from a fall on the hand, or from direct violence. The forearm is the most frequent site of green-stick fractures; the deformity usually is very apparent (Fig. 34(j), and the treatment consists in reducing this, which usually involves making the fracture complete ; but as this frequently is accomplished without much rupture of the periosteum, there is little or no tendency for the fragments to be displaced subsequently. The forearm is dressed as in complete fractures. In these the radius usuallv is broken a little higher than the ulna, and one 356 FRACTURES or both bones may be comminuted (Figs. 347 and 34S). The diagnosis is easy, ovs'ing to the extreme mobility. Reduction should be attempted Fig. 346. — Green-stick fracture of both bones of forearm one month after injun,- which was untreated. Reduced under anesthetic. Children's Hospital. by fully supinating the forearm, and making extension and counter- extension so as to overcome any overlapping. Correct replacement Figs. 3-17 and 348. — Skiagraphs of comminuted fracture of both bones of forearm ; delayed union at end of ten weeks. Patient, aged fifty-three years, then returned to work as blacksmith, and two months later union-was firm. Episcopal Hospital. of the ulnar fracture usually can be determined clinically, as this bone is subcutaneous; Init the radius is buried among so many muscles FRACTCRES OF THE FOREARM 357 tliat a skia^'rapli frrf|iUMitly is necessary to ascertain the position of the t'ra'Mnents if the fracture is al)()ve the middle of the hone. ^Fk;. 349.— Dressing for fracture of both bones of forearm. Padding oniitt(;d. Note length of splints. Forearm in full supination. Episcopal Hospital. Fig. .350. — Skiagraph of fracture of both bones of forearm, before reduc- tion; lateral view, in mid-pronation. Age nine years. (See Figs. 351, 352, 353.) Episcopal Hospital. Fig. 351. — Skiagraph of fracture of both bones of forearm, before reduction; antero- posterior view. (See Fig. 350.) Episcopal Hospital. The forearm is then dressed in fvll supinatwn between two straight splints, that on the flexor surface extending from the bend of the 3oS FRACTURES elbow to the tips of the fintrers, while the dorsal splint extends from the olecranon to the wrist (Fig. 349). These splints should be a little wider than the forearm, so as to prevent crowding the bones together laterally, and they should be smoothly but thickly padded. Apply the spliiits with the elbow flexed to a right angle, and make sure that the palmar splint does not compress the veins in the bend of the elbow. A longitudinal pad placed between the bones, in the eft'ort Fig. 352. — Skiagraph of fracture of both bones of forearm after reduction. Antero- po.sterior view, in full supination. Same case as Figs. 350 and 351. Episcopal Hospital. Fig. 353. — Skiagraph of fracture of both bones of forearm after "reduc- tion." Recovery with perfect func- tions and no palpable deformity. Epis- copal Hospital. to wedge them apart is not only useless but harmful. Extra com- presses, however, may well be placed over any of the fragments that tend to project. The splints are then strapped snugly around the forearm and held securely in place by a roller bandage. A large "handkerchief" or "triangular" sling is applied, and the forearm carried against the chest, but always in full supination. I urge the employment of this position not only because supination is the most difficult part of rotation to regain, and because the upper fragment FRACTURES OF THE ('ARFVS 359 of the radius usually is kept in supination by the biceps, but because I lia\e found, if the forearm is ilressed in niid-pronation, as is com- monly ad\iscd now, that the fraj^ments saj^ by the force of gravity, and the j)aticnt recovers not only with lost sui)ination, but with angular deformity of both bones toward the ulnar side. If attempt is made to correct this deformity by adjusting a coa{)tation splint over the angular projection of the ulna, this may be overcome, Init the surgeon will succeed merely in forcing the ulna nearer the radius, which camiot be influenced by such an appliance, and the disability as regards rotation will be increased. It often is exceedingly difficult to keep these fractures even approximately reduced during the first week; but usually a little better position can be secured at each Fig. 3.54. — .Skiagraph of fracture of carpal scaphoid. Compare with normal wrist in Fig. 3.5.5. Episcopal Hospital. dressing, and when the ends of the bones begin to become sticky, during the second week, it will be found that deformity daily becomes less, and what looked at first like a hopeless case, will result in a very useful arm, and one with slight or no visible deformity. Skiagraphs are valuable and interesting, but I advise the inexperienced not to be terrified by the appearance of the bones in a skiagraph into think- ing that only operative treatment can give his patient a good result. If he uses the eyes in the ends of his fingers, he will secure by con- servative means quite as good, and in many cases a much better result than by operation, and in a shorter time (Figs. 350, 351, 352, and 353). Carpus. — Of these fractures, that of the scaphoid is least unusual, resulting usually from a fall on the thenar eminence; the diagnosis 360 FRACTURES is made from tenderness in the "anatomical snuffbox," sometimes l)y dorsal displacement of one of the fragments, and effusion in the Fig. 355. — Skiagraph of normal wri.st. Compare with Fig. u.Ji. Episcopal Hospital. radio-carpal joint. Confirmation by a skiagraph is advisable (Figs. 354 and 355). Treatment consists in excision of an irreducible frag- FiG. 356. — Dressing for fracture of metacarpals. Hand bandaged over a roller. Episcopal Hospital. ment, and in immobilization on a palmar splint for three or four weeks for those cases without deformity. FRACTURES OF THE METACARPUS 361 Metacarpus. Fractiirrs of the metacarpals result usually from (lirrct violence (pri/c-fiKlitinj,', etc.); the (lisi)laeement is au^nilar, toward the extensor surface, and may he difhcult to keep reduced. Fig. .357. — Fracture of base of thumb metacarpal. Episcopal Hospital. The hand may be dressed on a palmar splint, the palm being well padded; or may be bandaged over a firm roller, the tension on the Fig. 358. — Dressing for fracture of the phalanges. Episcopal Hospital. extensor tendons preventing deformity (Figs. 350) . Fracture of the base of the tJmmb metacarpal (Bennett, 1886), may resemble a subluxation of that bone (Fig. 357). 362 FRACTURES Phalanges. — Fractures of these usually are caused by direct violence, often being compound and requiring amputation. Simple fractures are dressed on antero-posterior splints (Fig. 358) for about three weeks. If angular deformity toward the flexor surface persists, due to the pull of the interossei, Stimson (1907j advises dressing the fingers in flexion over a roller bandage. FRACTURES OF THE LOWER EXTREMITY. Femur. — This is the most serious fracture of the extremities that a patient can suffer, but fortunately it is less serious in children, in whom it is more frequent, than in adults. In adults fractures of the leg are much more frequent than in children. The fractures of the femur may be grouped into those of the upper end, those of the shaft, and those of the lower end. Fig. 3.59. — Fracture of neck of femur close to its head. Episcopal Hospital. Fractures of the Upper End of the Femur. — Fractures of the neck of the femur ("fracture of the hip") are more common in adults, especially those past sixty-five years of age, than in children. The trauma in the aged often is trivial as their bones are more brittle; some cases are caused by a mere twist of the leg, catching it in a FHACTUJiES OF THE FEMUR 363 fold of tlu' cariH't, on an uneven paving' stone, etc., or by sitting down suddenly. Such injuries usuall\ produce a fracture of the neck close to the head (intracapsular), and seldom are iui[)acted (Fig. iiolJ). Falls on the great trochanter, especially in ])atients under seventy years of age, are more apt to result in an impacted fracture close to the trochan- ter (Fig. ;)()()), which is at least partly extracapsular. In children, also, fractures of the neck of the femur usually are impacted, or partial; or an epiphyseal separation of the head may occur. In impacted fractures, the impaction occurs chiefly at the expense of the posterior i)art of the neck, the shaft of the femur being rotated outward as the posterior margins of the fragments are driven together. Fig. 360. — Impacted fracture at base of neck of femur. Age sixty-five years. Note also coxa vara. Episcopal Hospital. Symptoms. — ]\Iuscular spasm is prominent, and this, with local- ized pain and tenderness, sometimes are alone sufficient to warrant the diagnosis in the aged. In unimpacted fractures the patient usually is unable to raise the limb from the bed; deformity is char- acteristic, consisting in eversion of the lower extremity, the fibular side of the foot lying on the bed; and there is moderate shortening (2 to 4 cm.), which frequently increases during the second day. In 364 FRACTURES impacted fractures the shortening may not exceed 1 cm. Normally when the thigh is flexed the great trochanter lies on a line drawn from the anterior superior spine of the ilium to the tuber ischii (Xelatons line, 1847); but when there is fracture of the neck of the femur the muscles (ilio-psoas, adductors, hamstrings, glutei) passing from the pelvis to the shaft pull the lower fragment up, so that the trochanter lies above this line, and approaches or even ascends above a plumb line dropped from the anterior superior spine when the patient is lying supine i Bryanfs line, lS79j; the relation of the trochanter to Xelaton's and Bryant's lines on the two sides should be compared (Figs. 361 and 362). The trochanter is less prominent on the injured side owing to the loss of support from the neck of the bone, and by placing the tips of the fingers between the trochanter and iliac crest it will be found that the fascia lata on the injured side is relaxed (Allis's sign, 1877). Sometimes from the shortening a fold or wrinkle is formed over the tendo patella, and can be smoothed out by making Fig. 361. — Xelaton's line: passes from anterior superior spine of ilium to tuber ischii and crosses tip of great trochanter of femur, when thigh is partly flexed. Fig. 362. — Bryant's line, a plumb line from anterior superior spine of ilium, patient supine. Orthopaedic Hospital. extension (Cleemann, 1876). In cases without impaction, mobility is present: tliis may be detected by rotating the entire limb, when it will be found to have a greater range of motion than the uninjured limb; and by pushing upward and pulling downward in the axis of the limb, the greater trochanter will be found to .slide up and down on the pelvis. During these manoeuvres crepitus usually is elicited. By palpating the trochanter as the limb is rotated, it will be found to rotate in the arc of a smaller circle than the trochanter on the uninjured side; this is because the centre of motion is trans- ferred from the acetabulum to the seat of fracture. Usually there is an abnormal fulness over the head of the femur (just below Poupart's ligament, beneath or immediately external to the femoral artery) owing to effusion in the joint and the external rotation of the outer fragment. Diagnosis rarely is difficult in the adult, attention being paid to the history of injury, even if slight, and to the cardinal physical signs, shortening, eversion, and crepitus. In cases with impaction. FRACTURES OF THE FEMl'R 3Go wliere in()l)ility and crepitus are al)sont. and wlicrc evcrsioii and sli()rt(Miin•>•"))• The lateral traction, which should draw the femur slij^ditly away Fig. 365. — Longitudinal and lateral traction for fracture of neck of femur. No(n also use of Volkmann's sliding foot splint to prevent rotation of limb. Episcopal Hospital. Fig. 366. — Fracture through trochanter.s (if femur; rare and atypical line of fracture. Episcopal Hospital. 368 FRACTURES from the plane of the bed as well as laterally, overcomes eversion and keeps the capsule of the hip-joint tense, preventing it from falling in between the fragments. Every two or three days the longitudinal traction should be substituted by traction with the hands upon the thigh, and the knee should be flexed gently through about 30 degrees to prevent stiffness. Union is good at the end of four weeks. Ruth found in 1907 that among a total of 72 cases treated by this method there had been no failure of union in patients under eighty years, no failure to secure a useful limb under seventy years of age, and in those past eighty years of age success was obtained in over 60 per cent, of cases. Impacted fractures are treated in the same way, but less weight is required. Fractures through the trochanters of the femur are not very rare, usually are due to great direct violence, and often are impacted. Three grades of this injury may be recognized (Ashhurst, 1913): the first is little more than an impacted fracture at the base of the neck; in the next, the neck penetrates the trochanteric region further, and a splitting fracture occurs; and in the severest grade the trochanteric region is entirely shattered. A linear fracture between the level of the trochan- ters is quite rare (Fig. 366). In most cases the lesser trochanter is fractured (Fig. 367). Binet and Hamant (1911) have collected eight cases of isolated frac- ture of the lesser trochanter. Isolated fracture of the great trochanter occurs, and may require periosteal suture to maintain reduction. Fractures of the Shaft of the Femur. — These are much more common in children and young adults than in old people, and usually are due to direct violence. There are three main types: (1) Fracture heloiv the trochanters. The upper fragment is flexed by the iliopsoas; and rotated outward by the gluteus maximus and the short external rotators. The lower end of the upper fragment often is felt as a sharp projection in Scarpa's triangle; while the lower fragment is drawn upward and inward by the adductors (Fig. 368). The leg rolls out- ward from its own weight, and shortening is marked. Crepitus and abnormal mobility are easily detected. (2) Fracture of the middle of the shaft, often oblique (Fig. 272), is attended by more shortening than any fracture in the body, sometimes as much as 12 cm. (five inches); the leg rolls outward, there is flail-like motion and marked crepitus at the seat of fracture; the lower fragment is drawn up and in by the adductors and hamstrings, and the upper fragment projects anteriorly Fig. 367. — A common type of fracture through the trochanters: fracture at base of neck of femur (impacted) ; with separation of lesser trochanter. Age forty-five years. Episcopal Hospital. FliACTUliES OF THE FEMUR 369 (Fi^. 'M\\)). (o) SiiprdroiKJi/htrfrdcturcs are cliaractori/od ])y i)()sterior (lisi)la(riiu'iit of tlio lower tragmeiit wliieh is kept flexed at the knee by the ^astroeiiemiiis (Fig. -iTl); and hy anterior projeetion of the upper fragment, wiiieh may be embedded in the reetus musele. The diagnosis of these ^■arious types of fraetnre of the shaft is not difficult, since the displacement is fairly constant, and if deformity is great the ends of the fragnuMits ustiall> can i)e ])alpate(l even in \ery nuiseular limbs. Fig. 368. — Fracture of femur below trochanters. Episcopal Hospital. Prognosift. — The general mortality is about 15 per cent.; 90 per cent, of those who recover under conservative treatment secure entirely useful limbs, but about one out of three of these will have a limp, and only about one patient out of four will have no shortening (Ash- hurst and Newell, 1908). Though many surgeons urge the operative treatment of recent fractures of the femur as a routine, I am not aw^are that they have published figures demonstrating even as good results as the above. Treatment. — Reduction of the fracture is difficult, but probably could be more often obtained if the patient was anesthetized. Weight 24 370 FRACTURES extension should be applied in sufficient amount to overcome shorten- ing. Ochsner has found that if the adhesive plaster is carried up to the groin, irrespective of the height of the fracture, weight extension is much more efficacious. I'he full amount of weight necessary should be applied during the first day or two after the accident, since shortening becomes more difficult to overcome the longer it lasts. By raising the foot of the bed from four to six inches, counter-exten- sion is provided by the weight of the patient's body. If necessary Fig. 369. — Pkiapraph of traiisvcrso fracture of shaft of femur. Best po!rous Fio. 376.— Fracture of patella with wide separation of fraj^ments, showing power of full extension six years after injury. No operation was done. Episcopal Hospital. union results, and if after getting about the bond of union stretches, as it frequently does, the power of extension of the knee may f>e retained Fig. .'i77. — ltn<:ynr<: of j^at'-lla \,ii'ti'- '-(/'/.ition. Age twenty-eight years. Episcopal Hospital. (Tig. 370j; but in almost all cases there will be slight limp, and some disability in gc>irig up stairs. Ojjeration is best done between the fifth I'liACrVUKH OF Till': IWTKLLA 375 iiiid tent li (lays jit'lcr iiijiifv ; cjirlicr iii(cr\ ciil imi ^(»Ill(•t iiiics is lollowcd l).\ iiilcct ion, <-iii(l inrcctioii in w kiu'c-jointor this kind nsniilly r('(|iiir('S iinipiitiitidii, ;iiid may rcsiiM in the pjiticiit's dcMlli. Tlic inortidily ot" ojMTJition ex (Ml inidcr the l>rst conditions ni;iy rc;icli I |)(r cent. (Iv (1. Alexander, Mill). The slrielest aseptic teehni(|ne is inipeni- tive. A seniihuiar llap is turned (h)\vM or up, ex|)osin^' the seat of fracture. The knee-joint is widely o])ene(l, and clots are removed by forceps or sponuini;' with moist \i,\\\\/.v. Any frinjics of the (piadri- cops aj)oueurosis turned down hetweeu the fra^nncnls are everted, Fig. 378. — •Fracfurc of piitdl.-i riftcr siidirc willi r'litoiiiic cattiut. I'lpi.scdpal Hospital. and two holes are drilled in each fra^ineiit, from the superficial to the fractured surface, not in\'adinjf the articular surface of the patella. The fragments are then sutured with a mattress suture of heavy chromic catgut or wire; the quadriceps expansion and capsule are sutured with chromic gut; and the skin with interrupted silkworm gut (Figs. 'Ml and 'MX). In some cases it is suflicient to suture the fibrous tissues alone, without direct suture of the bone (Blake, Gibbon, 1904). If all oozing has been checked, and the skin is not sutured too tightly, it is not necessary to drain the wound; otherwise a small drain 376 FRACTURES should be left for forty-eight hours. The limb is dressed on a posterior splint, which may be removed in a few days and the limb laid on a pillow, with the knee slightly flexed. Most surgeons now recommend l)eginning very gentle passive motion four or five days after operation, bv raising the knee a few inches from the pillow once daily. Xo active motion should be allowed for at least two weeks, and not then unless the bone has been sutured with wire. If wire has been used, the fragments depend on it for their apposition and not on the newly formed callus. True bony union seldom results, and if absorbable bone sutures have been used, the knee should be supported by a posterior gypsum splint, or light brace, to prevent excessive flexion, for eight weeks or more after operation. With non-absorbable suture the patient may begin to walk without support in three or four weeks. If wire has been used it may require to be removed. Ilefracture is not verv rare. Fig. 379.- ^kiag^aph of partial separation of upper epiphysis of tibia. (Schlatter's disease.) Episcopal Hospital. Tibia. — These fractures frequently are caused ])y direct violence, except those of spiral type following twists of the foot, and those of the internal malleolus accompanying fracture of the lower end of FRACTURES OF THE T/IilA 377 the fil)iila. The suhcutaneous position of tlie tibia, aiul the fact that it sujiports the main weight of tlie body, render it mnch more liahlc to i!ijiir\- than the fibula, fractures of tlie shaft of whicli rarely occur except as secondary lesions in fractures of the tibia. The fractures from direct violence often are compound or comminuted. Fmcturcs of Ihc upper end of the tibia fretjuently run into the knee- joint (Fig- -~^'). !•" hand is brought down to the opposite shoulder, and the hone usually will he rci)laced. Fig. 399. -Kocher's method of reducing dislocation of .shoulder, first step: outward rotation. Episcopal Hospital. T. Kuchcr's Method of Reduction. — (1) Bring the elbow against the chest, and rotate the humerus outward as far as it will go, using the bent forearm as a lever (Fig. 399) ; do not push this outward rotation too far, and do it with a very gradual and gentle but persistent motion ; force is very liable to fracture the humerus; Kocher himself broke it three times in reducing twenty-eight luxations. During this out- ward rotation of the humerus the same phenomena occur as during Fig. 400. — Reduction of dislocation uf shoulder by Kocher's method; second step: elevation of arm in sagittal plane. Episcopal Hospital. step two of Smith's method, but the lesser tuberosity may catch under the tense coraco-l)rachialis, and this is one cause of the frequency of fracture of the humerus (G. G. Davis, 1910). (2) Raise the elbow in the sagittal plane, or in slight adduction, until the arm is as nearly vertical as possible (Fig. 400) ; this relaxes the anterior border of the 398 INJURIES OF JOINTS rent in the capsule (coraco-humeral ligament), and the coraco- brachial is and short head of the biceps, which hinder the ascent of the head on to the glenoid process. (3) Rotate the arm inward, using the bent forearm as a lever, until the hand touches the sound shoulder, then quickly bring the elbow to the side of the chest (Fig. 401). This last step slides the head of the bone back through the rent in the capsule, whose posterior untorn part is now on the inner instead of the outer side of the humerus, and again acts as a fulcrum to lever the head upward; but reduction often is accomplished at the conclusion of the second step. Fig. 401. — Reduction of dislocation of shoulder by Kocher's method; third step: hand brought to shoulder and elbow to chest. Episcopal Hospital. Of these two methods, Smith's undoubtedly is the better, though neither of them rests on the anatomo-pathological basis which was erected for them by their authors; Smith thought the muscles the all important factor, while Kocher thought success depended on the gleno-humeral ligament, which was shown by Farabeuf to be of no consequence. The great advantage of these methods of manipulation is that an anesthetic usually is not required in recent cases, and that they can be applied by the surgeon without other assistance than the inertia of the patient's body. They depend for their efficiency, however, on the untorn state of the posterior part of the capsule; if this portion also is torn, the head of the humerus will not be pulled away from the chest during outward rotation, but will rotate in situ. Under such circumstances the rent in the capsule will be so large that no difficulty should be experienced in replacing the head of the bone by direct pressure, after it has been drawn away from the chest by extension and counter-extension. The methods of direct reposition are many; all of them depend first on bringing the head of the bone opposite the tear in the capsule, and consequently aivay from the chest umll and out to the neighborhood of the glenoid process; and then on pushing or pulling it into its socket. The head can be brought away from the side of the thorax only by eliminating or overcoming the muscular contraction which holds it there, either by continuous traction or a general anesthetic. DISLOCATION OF TlIM SIIOULDEIi :]{)9 1. Sir A.silcy Cooper's Method (1822): With tlic patient supine, plaee the heel of the luihooted foot in the patient's axilla, against the chest, and make traction downward and slightly outward on the upper extreuiitx'; the traction ])ulls the head free from the eoraeoid, and l)v slight Ie\erag{> o\(T the foot, the head is pushed directly into its socket. A little rotation in and out may assist. This is a very efficient method, really combining all others (extension and counter-extension, leverage, and mauii)ulation), but it is very painful and usually re(iuires anesthesia; and the inexpert or brutal may cause serious injury to the axillary tissues. 2. Stimsons Method (1900: The patient is laid on a canvas sling, with the dislocated extremity passed through a hole in the canvas and hanging free of the floor; a weight of about ten pounds is attached to the wrist or elbow. The liml) is kei)t thus in abduction, and in a few minutes (never more than six, Stimson) reduction of the dis- location takes place quietly and without pain. No anesthetic is required, as the weight tires out the muscles which hold the head of the humerus against the chest; and as soon as it is drawn out to the region of the glenoid process, it slips into its socket spontaneously. 3. Malgaigne's Method (1855) is the reverse of Stimson's: The patient lies on the sound side on the floor, and a robust assistant pulls vertically upward on the dislocated extremity, till the shoulders just clear the floor, and maintains this traction till the patient's axillary muscles are exhausted; the surgeon then pushes the head of the bone into place. ]Many other modifications of this principle have been devised, and constantly are being reinvented by ingenious surgeons. In ijostcrior dislocations upon the cadaver I have succeeded in securing reduction by reversing the manipulations of Kocher's and Smith's methods; but usually in life the capsule is so widely torn that the luxation is easily reduced by direct pressure forward or very slight manipulation. After reduction, the arm is dressed in the Velpeau position and guarded use may be permitted after two weeks. It is possible that if reduction were accomplished more often by manipulation and less often by brute force less disability as the result of periarthritis would follow this injury. Yvert (1911) has studied the statistics of various surgeons and finds that 65 per cent, of the patients had persistent disability, 22 per cent, had fairly satisfactory function, and only 13 per cent, had excellent results. Elbow. — The typical dislocation at the elbow consists in backward displacement of both bones of the forearm; anterior dislocation of both bones is rare; and lateral dislocations usually are incomplete and often accompanied by fracture of one or other of the humeral condyles. Posterior Dislocation, — Posterior dislocation is most frequent from fifteen to thirty years of age, and results almost invariably from a fall on the out-stretched hand causing hyperextension of the elbow, the olecranon acting as a fulcrum and prying the bones apart; the 400 INJURIES OF JOINTS anterior capsule is ruptured, and the internal lateral ligament more or less lacerated, and detachment of the epitrochlea of the humerus often occurs. Fracture of the olecranon by compression sometimes is seen, and occasionally the coronoid process is broken off. Fig. 402. — Old unreduced posterior dislocation of elbow, with evidences of hypertrophic arthritis. Episcopal Hospital. Symjjfoms. — The deformity usually is ciuite apparent. The fore- arm, usually pronated, is carried at an obtuse angle with the arm, and motion is painful and restricted. The radius and ulna may be displaced directly backward, but often there is also slight lateral displacement. The olecranon is found displaced posteriorly and upward in relation to the condyles, and the greater sigmoid fossa of the ulna often can be felt between the tense triceps and posterior surface of the humerus (Fig. 402). The head of the radius is absent from its normal place just in front of the external condyle and can be felt posteriorly. Anteriorly the lower extremity of the humerus fills the flexure of the elbow. The diagnosis from supracondylar fracture, referred to at p. 341, should present no difficulties, and in case of doubt, the lesion is much more likely to be a fracture than a dis- location. If the lesion is recognized, and the luxation promptly reduced, recovery is rapid, and in most cases nearly perfect function is secured. Treatment. — In recent cases, especially in children, reduction without an anesthetic is easy, by reversing the steps by which the lesion was produced: first hyperextend the elbow, until the tip of DISLOCATION OF THE ELBOW 401 the olocraiion strikes the humerus, and the coronoicl is freed from the trochlea; tiien make extension and counter-extension in the axis of the arm, pushing the lower end of the humerus backward; and finally acutely flex the elbow, when the bones will be replaced with a snap. Often the pressure of the thumbs over the lower end of the humerus, and that of tlie clasped fingers over the posterior surface of the olecranon, is sufficient to secure reduction (direct method); or the knee may be placed in the bend of the elbow and used as a fulcrum to lever the bones of the forearm away from the humerus by traction on the wrist with one hand, while the humerus is pushed backward with the other hand (Fig. 403). The elbow is dressed in hyperflexion (p. 347), for a week, and then carried in a sling for another, and after two weeks guarded active use is encouraged. Lateral Dislocation. — External dislocation often is due to direct violence, usually is incomplete and complicated by fracture of the external condyle, and extensive rupture of the internal lateral ligament Fig. 403. — Mechanism po.sterior di.slocatioii of i the knee. of reduction of ;lljow by aid of Fig. 404. — External lateral disloca- tion of elbow, with fracture of external condyle, and rupture of internal lateral ligament and fracture of epitrochlea. Dr. W. Walker's case. Episcopal Hospital. Fig. 40.5. — Inward dislocation of ulna and radius. Dr. De Tar's case. Patient fell and while lying on left elbow train struck him upon buttocks. Reduction easy under anes- thetic. (Fig. 404). Internal dislocation is rarer than external, and fracture is a less usual complication (Fig. 405). In both forms the deformity is so extreme and the bony processes so easily palpable that, if careful examination is made before swelling obscures the landmarks, the 26 402 IXJCRIES OF JOINTS diagnosis should not be difficult. Reduction is easier to secure than to maintain, especially if fracture exists. The elbow should be dressed in hyperflexion and treated as a fracture. Forward Dislocation. — Forward dislocation of both bones at the elbow is very rare; even including seven cases in which the olecranon was broken off and remained in place, the total number on record, according to Stimson, is less than twenty-five. Fracture of the epi- trochlea is a frequent accompaniment. Reduction is not difficult, as both lateral ligaments are lacerated. Dislocation of the Ulna Alone from the humerus is most often pos- terior; the symptoms and treatment are much the same as when both bones are so displaced. Fig. 406. — Anterior and outward dislocation of head of radius, with fracture of shaft of ulna. Four months after injury. Episcopal Hospital. Dislocation of the Head of the Radius usually occurs in an anterior direction. The orbicular ligament may remain intact, the radius slipping out of its grasp, and subsequently being displaced forward by the pull of the biceps; often it is the result of a fracture of the upper part of the shaft of the ulna, from direct violence, the con- tinuance of the fracturing force driving the head of the radius forward (Figs. 40(3 and 407). This combined lesion is so freciuent that the recognition of either a dislocation of the radial head or a fracture of the upper end of the ulna should make the surgeon suspect the existence of the complicating lesion. Examination may detect a hollow in front of the external condyle, and the head of the radius a little forward from its normal position; flexion of the elbow beyond a right angle may be prevented by contact of the radius with the humerus. Reduction sometimes may be secured by full supination and direct pressure upon the displaced bone; and flexion will then become possible. DISLOCATION OF THE WRIST 403 Reduction sliould he obtained at all hazards, l)y arthrotomy it' neces- sary. Only after reduction of the radial flislocation has heen secured can the fracture of the ulna he reduced. If re-dislocation of the radial head occurs after keepin<; the elbow hyperflexed (p. ?A1) for several weeks, it may be assumed that the radial head had not been replaced within the orbicular lijjament; and an operation may be necessary to hold it in i>lace. In cases of complete dislocation it is very unlikely that reduction can be secured without operation. In old unreduced luxation, excision of the radial head may be done to permit flexion of the elbow, but in children this should be avoided if possible, since removal of the ei)ii)hysis will interfere with development. Fig. 407. — Anterior and outward dislocation of head of radius, three months after reduction by arthrotomy and capsulorrhaphy. Episcopal Hospital. In young children a subluxation known as "pulled elbow" occurs: this is due to vertical traction on the forearm, often produced as the caretaker helps or lifts the child across an obstruction in the street. If the forearm is supinated the vertical traction tends to bring the fore- arm and arm into a straight line, causing momentary loss of the carry- ing angle; or forced pronation may pry the radius forward over the ulna as a fulcrum. Symptoms of pulled elbow are rather indefinite, and in many cases no definite history of trauma can be obtained; it is merely noticed that the arm is not used properly, and that there is tenderness around the elbow. Treatment of "pulled elbow" consists in securing reduction of the subluxated bone by the same methods employed in cases of complete dislocation, and in preventing recurrence (which is not very rare) by keeping the elbow at rest for a week. Wrist. — Dislocation of the radio-carpal joint, usually consisting in dorsal displacement of the carpus, is very rare; Stimson classes Barton's fracture (p. 355) more as a complication of this dislocation than as an independent lesion. It is produced usually by the same injuries as Colles's fracture, and the differential diagnosis is 404 INJURIES OF JOINTS not always easy; but if it is possible to feel the styloid processes of the radius and ulna still attached to their respective bones, and to ascertain that the length of the bones of the forearm remains the same on both sides of the body and to feel the very abrupt eminence on the dorsum caused by the displaced carpal bones, confusion between fracture and dislocation is not apt to occur. Besides, the luxation is reduced by an elastic snap, without crepitus, and without tendency to recurrence. I have seen one case myself, easily diagnosed clinically by attention to these details. The diagnosis may be confirmed by a skiagraph. Spontaneous Siihhi.ratiun of the Wrist {Madelumfs Disease). — See p. 542. Dislocations of the carpal hones are not very uncommon, particularly forward dislocation of the semilunar, associated or not with fracture of the scaphoid. The bone is palpable under the flexor tendons, and there is a gap on the extensor surface between the os magnum and radius. The other carpal bones, most often scaphoid or os mag- num, usually are dislocated backward. If reduction is not easily secured, the displaced bone should be excised. Metacarpus. — The metacarpal bones rarely are luxated, the dis- placement usually being posterior. Phalanges.— The proximal phalanx of the thumb not infreciuently is dislocated posteriorly on the head of its metacarpal bone by hyper- extension, sometimes in a fight, a fall, or in the effort to push a tight stocking off the heel of the foot. The deformity is quite characteristic (Fig. 408), the phalanx in well-marked cases making a distinct angle with the metacarpal bone, the head of which is easily palpable in front; the distal phalanx remains flexed, owing to ten- sion on the flexor longus pol- licis, which is displaced to one side or other, usually the ulnar side of the metacarpal. The head of the metacarpal is "button-holed" through the anterior ligament; the tendons of the flexor brevis blend with the lateral ligaments, and it is the tension of these lateral ligaments, which fit like a collar around the neck of the metacarpal, that may render reduction impossible. In some cases reduction can be effected without anesthesia, (1) by pressing the metacarpal bone toward the palm, so as to relax the short thumb muscles; (2) by sliding the base of the phalanx over the head of the metacarpal, keeping the phalanx in hyperextension until the head of the metacarpal has been cleared. If reduction is impossible, an incision is made along the radial border of the flexor surface of the Fig. 408. — Dislocation of metacarpo-phalan- geal joint of thumb. Reduced by arthrotomy. Episcopal Hospital. DISLOCAriON OF THE HIP 40.") j)r()iniii(Mit liciid of the tliuml) iiictacarpiil, :iih1 tlic cxtcriKil liitcnil li<,Miiu'nt is (li\i(lc(l close to the pluihiiix. J)i,s'locaii(m.s of tlir inlrriihdhiiKjnd johils of the lingers almost always takes place posteriorlx , from li\ iMTextensioii, in falls or l)lo\vs on tiie fin<,'er tips (V\^. 4()i»). Hediiction usually is easy, but a joint fracturi' of the i)roxinial hone may exist, and some deformity may result. Treatment is the same as for fracture of a i)halanx. Jjitrntl dislocation usually is ineom])lete (Fig. 410). Fig. 409. — Posterior dislocation of niitldle phalanx on iiroximal of fifth finger. Episcopal Hosijital. Fig. 410. — Lateral dislocation of mid- dle on proximal phalanx. Episcopal Hospital. Sacro-iliac Joints. — ('omplete luxation is rare, hut subluxation, from sprain or long-continued strain is not unusual. ^Motion occurs antero-posteriorly around a transverse axis, and the usual displace- ment is of the upper end of the sacrum backward. Cricks and stitches in the small of the back, or severe backache may follow strain on these joint ligaments from stooping, from malposition in sitting or standing, or simply from lying long flat on the back, when the mus- cular support is weakened by anesthesia or constitutional disease. Relaxation of these joints sometimes is seen, and is best treated by orthopedic apparatus, gymnastics, etc. (p. 535). Hip. — Dislocation of the hip is a rare and rather a serious injury. The head of the femur is held in the acetabulum by a capsular ligament which is reinforced above and below by l)and-like ligaments, leaving the capsule weak anteriorly and posteriorly. The upper band-like ligament (ilio-femoral ligament of Bertin, 1754) is especially strong, and is known as the Y-ligament of Bigelow^ (1869); it is scarcely ever ruptured, no matter what the force that produces the luxation. Indirect violence is the usual cause, the femur being forced beyond its normal range either in flexion and adduction, or in extension and abduction, and the head of the bone being pried out of the acetabulum by leverage. In the cadaver luxations are most easily produced by hyperabduction, forcing the great trochanter against the posterior lip of the acetabulum, and using it as a fulcrum by which the head is lifted out of its socket; the capsule is then ruptured anteriorly below the ilio-femoral ligament, and the head of the bone passes on to the anterior plaiie^ of the innominate bone (Fig. 411). In patients, how- 1 Nekton's line divides the innominate bone into two planes (Alli.s, 1S96). 406 INJURIES OF JOINTS Fk;. 411. — Innominate bone showing the anterior and posterior planes. University of Pennsylvania. ever, the history of the injury generally indicates another mechanism, the femur having been in flexon and adduction, and the force having been received through an upward thrust in the long axis of the femur, or by a heavy weight falling on the pehis from behind. In such cases it is probable that the strong ilio-femoral ligament has been wound around the neck of the femur (inwardly rotated), acting as a sliding fulcrum; or possibly that the neck of the femur has been forced against the horizontal ramus of the pubis, and that the head has been pried out of the acetabulum over thi^ as a fulcrum. The capsule here is ruptured pos- teriorly, and the femoral head passes on to the posterior yJane of the innominate bone. Owing to the immense length of the distal arm of the lever (the whole lower extremity), it is not at all unusual for a dis- location primitively anterior to be converted into one of the posterior variety secondarily; in such cases the capsule may be widely lacerated, but in almost every case the ilio-femoral ligament remains intact, and the lower extremity is circumducted and rotated on it as a pivot. In general, then, two main types of dislocation at the hip may be recognized, anterior and posterior; and of each type there are several varieties, according as the head of the femur J rests high or low on the anterior or posterior plane of the pelvis (Fig. 412). Posterior Dislocations of the Hip, more frequent than anterior, are classed as high ("dislocation on the dorsum ilii," or "above the tendon" of the obturator internus), and low ("dislocation into the sciatic notch" of Sir Astley Cooper, 1822; or "below the tendon" of Bigelow 1869); and of these two the high luxation is much more frequent, though this may be only a secondary displacement, the head of the femur having emerged from the capsule lower than the sciatic notch, and having been displaced upward when the limb was extended. Fig. 412. — Usual sites of dislocation at the hip. A to B, Nelation's line. Posterior dislocations are (1) low; (2) high. Anterior dislocations are: (8) low; (4) high. See text. DISLOCATION OF THE II W 407 ^ynii>Uwts.-'T\\vve is loss of normal mohility; there is shortening, with flexion, addnetion and internal rotation at the hip; and in stand- ing the toes of the injured side rest on the dorsum of the other foot (^\^ 4i:i). The lower the position of the femoral head on the posterior Fig. 413. — Posterior (dorsal) dislocation of the hip. (Stinison.) plane, the more marked will be the shortening, flexion, adduction, and inward rotation. The head of the femur^ can no longer be felt below Poupart's ligament, beneath the femoral artery, but sometmies 1 A good working rule to remember is that the position of the internal condyle corresponds 1o that of the head of the femur, while that of the external condyle corresponds to that of the great trochanter (G. G. Davis, 1910). 408 INJURIES OF JOINTS can be detected posteriorly under the gluteal muscles; the trochanter is unduly prominent, is rotated forward, and is above Nekton's line. Anterior Dislocations of the Hip are classed as high ("pubic"), or low ("thyroid"), the latter, in which the head rests in the obturator foramen, probably being the primitive form in most cases; in the pubic form, the head rests against the horizontal ramus of the pubis; an exaggerated form of the high dislocation is the "suprapubic," and an exaggerated form of^the low dislocation is the "perineal," the head of the bone passing inward be- yond the thyroid foramen and across the ischium into the perineum. Symptoms. — ^AU these anterior dis- locations are characterized by im- mobility, flexion, abduction, and eversion of the limb (Fig. 414); in the low forms there may be apparent lengthening, but in the high cases there usually is actual shortening. The head of the femur generally can be felt beneath the pectineus or ad- ductor muscles, and often forms a visible prominence; the trochanter is rotated backward, and is less promi- nent than normally. Other Atypical or "Irregular" Dis- locations of the Hip occur, but are extremely rare, and are either sec- ondary modifications of those de- scribed above, or are caused by such \iolent trauma as frequently to cost the patient his life. The so-called "central dislocation of the hip" is discussed at p. 325. Prognosis. — If reduction is effected promptly, and without additional trauma, restoration of function is rapid, and generally complete; but Pennsylvania Hos- the longer rcductiou is delayed, and the greater the force required in ac- complishing it, the more unfavorable the outlook. But even in some cases of irreducible luxation, especially of the thyroid type, very fair use of the limb may be secured. Treatment. — Reduction of dislocation of the hip is accomplished either by the direct or indirect method. Direct Method. — In this, systematized by Allis (189G), the head of the femur is first brought into the position in which it burst tlirough the capsule, and is then pushed or pulled into the acetabulum. As in both anterior and posterior dislocations the head leaves the Fig. 414, location of hip pital. Anterior (thyroid) DISLOCATION OF THE HIP 409 acrtabiiliim in its lowor i)art, and as the capsnlc i)r(>l)al)Iy is widely torn below, the method ot" direct reposition is nearly the same for both varieties. The patient should be anesthetized anil laid on his back on a mattress on the floor, with the pelvis firmly fixed: flex the t\\\^\\ on the pelvis to a riu;ht an<(le, thus brin<;inff the head of the fenuir toward the lower part of the acetabulum; flex the knee to a ri, and is (hi\(ii throu,<;li Fig. 42(». — Hopkins's osteoclast. Urthopii'flic Hosi)ital. the bone by a mallet in such a way as to divide it trans\ersely all except a few fibres at the further side; several cuts in the bone (all at the same level) may be necessary, but they are all made through the one skin incision, making practically a subcutaneous operation. The Fig. 430. — Knock-knees, osteotomy of both femurs. (See Fig. 431.) Ortho- paedic Hospital. Fig. 431. — Result of osteotomy of femurs for knock-knees. Orthoptedic Hospital. remaining bone fibres are then fractured by hand, the incision closed with one suture, and the limb is put up in plaster of Paris in an over- corrected position. For knock-knee the osteotomy is done a finger's 422 DISEASES OF BONE breadth above the epiphyseal Une of the femur, usually on the outer side of the bone (Figs. 430 and 431); for bow-legs it is done at the Fig. 432. — Bow-legs, osteotomy of both tibiae. (See Fig. 433.) Ortho- pjedic Hospital. Fig. 433.— After osteotomies for bow-legs. Orthopaedic Hospital. apex of the deformity, usually only the tibia being di\ided, the fibula bending or being broken by hand (Figs. 432 and 433). The correc- Fig. 434. — Anterior curvature of tibite in rachitis. (See Fig. 435.) OrthopEedic Hospital. Fig. 435. — Anteriur cur\ature of tibite after osteotomy. Orthopaedic Hospital. tion of anterior curvature is more difficult (Figs. 434 and 435). The patient is not allowed to walk for six or eight weeks. OSTEITIS DEFORMANS 423 Scurvy. Scurvy, which may compHcatc rachitis or occur lude- pcndcutly, should' he hornc in mind as a possible cause of symptoms of bone disease in infants. Tenderness of shafts of long hones, with skiagraphic evidences of subperiosteal hemorrhages, in association with other scorbutic symptoms, should make one suspicious of this condition. The diagnosis from tuberculous or subacute septic osteo- myelitis is not always easy. Constitutional anti-scorbutic treatment is indicated. Fig 4.36 —Osteomalacia (five years' duration) in a patient, aged seventy-eight years. Confined to bed for six months. Fracture of right femur occurred the day before the photograph was taken, and death from asthenia two days later. Dr. F. W . .Sinkler s case. Episcopal Hospital. Osteomalacia.— Osteomalacia, or softening of the bones, is an affection occurring mostly in women, often in those who have borne several children in rapid succession. It is believed to be associated with ovarian disease. Scarcely ever does it occur before puberty. Deformity is progressive and marked, involving the pelvis, the vertebrarcolumn, and later the extremities. "Spontaneous fracture" (Fig. 43G) may occur, but is not frequent. The disease has been treated by oophorectomy, but some surgeons (Bastianelli) claim that the benefit from such operations has been due to the chloroform inha- lation used for anesthesia; and they now induce such anesthesia without doing an operation (W. J. Mayo, 1910). According to :Mayo, also, different Italian observers have found an identical and specific diplococcus in the periosteum in this disease, in rachitis, and in osteitis deformans; when a culture of this diplococcus was injected into rats it produced rachitis in the very young animal, and osteomalacia in adult rats. The relation of thyroid diseases to osteomalacia is not Osteitis Deformans {Paget' s Disease of the Bones, 1876) occurs in adult life, patients usually not applying for treatment until well past forty years of age. It runs a very chronic course, lasting many years, and"^ growing progressively worse, though intermissions and exacerbations may occur. It is characterized in its earlier stages by osteoporosis, causing flexibility and deformity of the bones; but later the bones hypertrophy and become markedly thickened. Frac- ture is rare. The lower extremities are affected earliest, resulting 424 DISEASES OF BONE in general outward and anterior bowing of the knees and legs; the spine shows a long, rounded kyphosis, and the calvaria becomes very much thickened. At times the bones are very painful, but often progressive enlargement of the head is what first calls the patient's attention to his condition. Eventually loss of height is observed, the attitude resembling that of anthropoid apes, with bowed head, disproportionately long arms, and a waddling gait (Fig. 437). Some weakness and stiffness usually exist, but death occurs only from intercurrent dis- ease, usually pulmonary, or from advanced arteriosclerosis which is a prominent feature of the malady. Treatment. — Treatment is chiefly hygienic and dietetic. Thymus or thyroid extract may be of value. Pain may be relieved by application of proper orthopedic apparatus. Hypertrophy of Bone. — This may be com- pensatory, as when one of two parallel bones is removed for disease, the other may become hypertrophied. Or it may be the result of chronic irritation, as in thickening of a tibia underlying an old leg ulcer. In- crease in thickness and weight is commoner than increase in length, though the latter occurs to a marked degree in some ampu- tation stumps, (p. 200) ; sometimes, too, after fracture or tuberculous or inflammatory lesion of bone, actual increase in length may occur, or at least the affected bone may grow faster than the corresponding bone on the other side of the body. Leontiasis Ossea (Virchow, 1865) is a disease usually arising in youth, charac- terized by hypertrophy of the face bones, giving the face a leonine expression, due to the gradual obliteration of its features. The foramina in the base of the skull may be narrowed, causing exophthalmos, blindness, and paralysis of the various cranial nerves. Hypertrophy of the calvaria causes pressure on the brain, with headaches, convulsions, etc. No treatment is of avail. Acromegaly (P. ]Marie, 1886) is a disease of youth or early adult life, characterized by hypertrophy, enlargement and thickening of the apices and extremities of the skeleton — fingers, toes, chin, nose, etc.; while similar soft tissues also may enlarge — lips, tongue, ears, and even penis and clitoris. A rounded kyphos develops in the dorsal spine. Headache is the chief subjective s^■mptom. The disease often is caused by changes, usually neoplastic, in the hypo- I'lG. 437. — Osteitis defor- mans (Paget's disease) in a patient, aged seventy-two years. Duration twelve years. Orthopsedic Hospital. INFECTIONS OF BONE 425 pliysis (•(Tcl)ri; n skiagrapli may (lemonstratc (Milargcincnt of the sella tureica, and pressure syini)tonis from hypophyseal growth may develop later. Treatment by pineal, thyroid, thymus, or other extracts may he tried, but tlie only hoi)e of cure consists in removal of the hypophysis (see p. oS4). INFECTIONS OF BONE. Infection of a bone usually occurs through the blood-stream, some locus uiinori.s' rcsLstcntia', generally due to injury, determining locali- zation of the infection. Those who have a general blood-infection (furunculosis, typhoid fever, syphilis, tuberculosis, etc.), therefore, are predisposed to bone infection. Infection of bone also occurs in compound fractures, but as in these the products of inflammation are readily discharged from the broken surfaces and through the wound of the soft parts, the disease seldom assumes such .serious proportions as when infection arises in the unbroken bone; in the latter instance the very structure of the bone prevents swelling, so that strangulation and necrosis occur very early. Acute Periosteitis. — Acute periosteitis rarely occurs as an isolated affectioji; in almost every case there are also osteitis and osteomye- litis, and it is probable that the in- fection is localized first in the medulla, and is propagated to the periosteal surface of the bone through the Haver- sian canals. In convalescence from typhoid fever, however, subperiosteal abscess may occur, and in most such cases there is no appreciable involve- ment of the medulla, and at most only a superficial caries of the cortex. The lesion occurs of tenest in the long bones and the ribs; relief of symptoms (pain, tenderness, swelling, fever, etc.), and rapid cure usually follow incision of the periosteum and scraping the carious bone (Fig. 438). Chronic Periosteitis. — Chronic peri- osteitis is a frequent lesion, occurring in many of the dystrophies already de- scribed, or as the result of contusions of bone, from chronic inflammation of overlying soft tissues, and in chronic infections, especially syphilis (Fig. 400). The long bones are most often affected: the periosteum is raised from the shaft by the formation of new bone, and the resulting deformity may be very evident on inspection. Distinct periosteal Fig. 438. — Periosteitis of left tibia nine months after typhoid fever. Age nine years. Episcopal Hospital. 426 DISEASES OF BONE nodes may form, or the thickening may be diffuse. Usually there is a good deal of aching, but no very acute pain; the osteoscopic (bone- tiring) pains become worse after exertion and when the warmth of bed induces hyperemia of the diseased parts. The treatment is much the same as for syphilitic periosteitis (p. 442). Osteitis. — Osteitis scarcely ever occurs as a recognizable affection apart from accompanying osteomyelitis. Osteomyelitis. — This is an acute septic infection of bone marrow, usually due to the Staphylococcus aureus, and affecting mostly the long bones of the extremities, especially the tibia, femur, and ulna, in their juxta-epiphyseal portion, which is named by Kocher the metaphysis. It occurs almost exclusively in children from six to sixteen years of age, and often follows slight trauma, or exposure to cold and wet, as in frequent swimming expeditions. Predisposing causes are malnutrition, convalescence from the exanthemata or other general infections. Owing to the dense bony case in which the inflammation occurs, it is extremely rare for an abscess to form; instead a true phlegmon of bone results, infection spreading up and down the medulla. The cortex is affected secondarily, and in most cases periosteitis results from transmission of infection through the Haversian and \'olkmann's canals. The process rarely extends into the joints, even in adults, and in children nearly invariably is arrested at the cartilage of the epiphyses. Swelling being impossible, the medullary tissues become strangulated, and death of the bone in large masses follows (necrosis), its extent depending on the destruction of the marrow cells within, and on the amount of separation of periosteum on the surface. Some- times the entire shaft of the bone becomes necrotic, is spontaneously detached at its epiphyses, and floats in pus beneath the unruptured periosteum. Usually, however, before this stage is reached drainage is instituted by operation, or the periosteum is perforated by the pus with formation of a parosteal abscess in the soft tissues. The periosteum is raised from the cortex, and new subperiosteal bone is formed; this at first is plastic but later becomes sclerotic and is known as the invulucrum; and such portions of the bone marrow as survive form new bone within, so that eventually the necrotic portion of bone, known as a sequestrum, is more or less completely surrounded by new-formed bone but still communicates with the surface through orifices in the involucrum known as cloacoB, and through these a discharge of pus continues. Several sequestra may form, each having its own cloaca or cloacse, and discharging on the skin surface through numerous sinuses (Fig. 439). When this stage of the disease is reached, it assumes a chronic form usually described by the term Necrosis (p. 431). Symptoms. — These are both general and local, the former often so over-shadowing the latter that without attenpon to the history and careful physical examination the disease has been mistaken for toxemia resulting from typhoid fever, pneumonia, meningitis, etc. OSTEOMYELITIS 427 The disease may be usiiered in by a cliill, with sudden rise in tempera- ture to 10;')° F. or hi<^her, the child appearing very ill and making little complaint of the extremity afiectecl. In these hyperacute cases death from septicemia may occur within a day or two in spite of active treatment. In most cases, however, the affected limb becomes painjul, helpless, and swollen; redness may not be evident. Tender- ness is extreme, extending throughout the shaft of the affected bone, but most intense at one spot. Indeed, tenderness usually is so great N^.r'- ^^ '■■:■! Fig. 439. — Diagram of changes occurring in a case of acute osteomyelitis of the tibia. In the first figure, there is diffuse suppuration in the medulla of the diaphysis. In the second figure, the products of inflammation are seen, filling the space between the cortex and the periosteum. In the third figure, new subperiosteal bone has been formed, and within this involucrum is seen a large sequestrum, surrounded by pus, which dis- charges through openings in the involucrum, known as cloaca. In the fourth figure, only a small cortical sequestrum remains, the involucrum has become very dense, and the medullary cavity is replaced by eburnated bone, (de Quervain.) as absolutely to prevent palpation at the seat of greatest disease. Even if the remainder of the shaft be not tender to palpation or tappng, prolonged gentle pressure even at a distance will eventually and suddenly become acutely painful; this is a valuable diagnostic point (Nichols, 1907). The disease is often mistaken for acute rheu- matic arthritis, with most disastrous results; but in osteomyelitis the joints are not involved, while the bones are; and multiple lesions, common in acute rheumatic fever, are rare so early in the course of 428 DISEASES OF BONE osteomyelitis, though quite frequent hiter. Tlie distinction between deep-seated suppuration of bone, and serous joint efiusion should not be diffieult if physical examination is thorough. The mistake is most apt to occur in the case of bones which are not subcutaneous (femur, radius, humerus), but ignorance and carelessness may err even in the case of the tibia or ulna. At later stages, if the patient survives, edema of the skin, with redness, and even fluctuation, make a mistake absolutely unpardonable. Throughout the course of the disease the surgeon should be on the lookout for secondary invasion of other bones, which is often overlooked for some days, owing to a subacute onset. Fig. 440. — Skiagraph of acute osteomyelitis of femur; age seven years; treated at home for "typhoid fever" for four weeks. Episcopal Hospital. Treatment. — As soon as the diagnosis is made, the bone should be opened. Delay even of a few hours is dangerous in very acute cases, leading to widespread necrosis, pyemia, and multiple secondary foci of osteomyelitis in other bones. In a case of which I have cognizance, the patient was treated during four weeks for typhoid fever, with the result that not only was he gravely ill for many months with pyemia, but he lost his entire ulna, and developed secondary lesions in one tibia, and both femora (Fig. 440). The patient should be anesthe- tized, the limb elevated until bloodless, and an Esmarch band applied well above the diseased area; a free incision is then made dividing the periosteum where subcutaneous or after exposure through the proper intermuscular space. Usually the periosteum is found more or less widely detached from the cortex by pus; the cortex then may look white and dead, but generally a few minute bleeding-points (Volkmann's canals) may be seen. If the periosteum is detached from the cortex throughout, and the shaft is loosened at its epiphy- seal attachments, the entire shaft may be removed, either in one OSTEOMYELITIS 429 piece, or l)y wreiichiiig each ciul free after sawiiiji; the h(jiie across its centre; in the case of tlie femur and liurnerus, however, where no parallel hone exists to act as splint, it will })e better, even under these circumstances, to leave the shaft in place until an involucrum has formed dense enough to maintain the form of the limh. Where the i)eri()steum is only partly detached from the hone, or where the infection has not yet extended from the marrow out through the cortex, the cortical bone may appear normal; but in all cases the surgeon shonld open the viedulla to provide drainage. The periosteum should be carefully detached from a sufficient area, and the medulla exposed by trephine or g(^uge and mallet. The marrow usually is found softened, grayish yellow, or even purulent; but failure to find frank pus by no means indicates that septic osteomyelitis is absent. If the oper- ation is done sufficiently early the inflammation may not have progressed to the stage of suppuration; and in certain cases of subacute infection (perhaps tuberculous), there is what is known as albuminous osteomyelitis (Oilier, 1S72), the exudate being serous or at most sero-purulent. In such cases, or if the diagnosis is doubtful. Fig. 441. — Specimen of tibia ex- cised for osteomyelitis; below is seen the trephine opening made for ex- ploration; above, the large opening made by gouge and mallet. Finally the entire diaphysis was excised. Episcopal Hospital. Fig. 442. — Deformity following excision of radius twenty-five j-ears ago for osteomyelitis; useful hand ; man works as laborer. Episcopal Hospital. the marrow may be exposed by drill holes. If the medulla is found widely infected, a second button of bone may be removed at a dis- tance from the fir.st, to determine the extent of medullary implication; and the intervening bone may then be removed by gouge and mallet, cutting a long gutter in the cortex, and widely exposing the medulla. It never is proper to curette the marrow or attempt its removal in 430 OSTEOMYELITIS any way, any more than it is proper to curette an acute phlegmon of the soft parts (p. 51); it is probable that all the marrow cells are not destroyed, and such as still are living are very important agents in forming new cortical bone. The periosteum alone is not always capable of forming an entire new shaft. In exceptional cases total resection of the diaphysis, even if this is not wholly necrotic, may be done when a parallel bone exists to act as splint, if the osteo- FiG. 443. — Deformitj- from excision of tibia for osteomyelitis. Operation two years ago. Xow fourteen years old. Ankylosis of knee. Only upper and lower epiphyses of tibia remain, with about three inches of shaft above malleolus. Gannot stand on leg. Episcopal Hospital. myelitis is so widespread as to render probable total necrosis later, or if the patient's condition is so septic that prompt convalescence is demanded (Fig. 441 ) ; but such removal often leaves a deformed (Fig. 442) or helpless limb (Fig. 448), which later may require an orthopedic operation (p. 504). In the case of the humerus and femur, where the disease is not very acute, it is sufficient to trephine the bone at the limits of inflammation, and pass a drainage tube from one opening to the other through the medulla. If guttering has been Fig. 444. — Granulating wound two months after guttering (evidement) of tibia for osteomyelitis. Children's Hospital. done, the marrow cavity is firmly packed with iodoform gauze, the wound is left widely open, and is allowed to heal by granulation (Fig. 444). If the entire diaphysis has been removed, the same course may be pursued, or the periosteum may be sutured lightly together, obliterating the cavity, as advised by Nichols (1904). If operation has been done early enough, necrosis of the shaft may not occur, and permanent healing will follow the primary intervention. NECROSIS OF BONE 431 In most cases, however, portions of the cortex become necrotic, arc ext'oHated as seqnestra, and may require subsequent operation for their i-cnio\al. Chronic Osteomyelitis. — ^Tliis is rarer tlian tlie acute form of the dis- ease and is due to a less virulent infection. The bone is infiltrated witli purulent material, its lime-salts are more or less al)sorbed and the narrow cavity obliterated. Treatment. — Free drainage should be j)rovided, and, if possible, all the dis- eased bone should be gouged away. _ .i-1?'Jt Recurrences are frequent unless radical operation is done. Eventually hyper- trophy, sclerosis, and eburnation occur. Necrosis. — Necrosis is the term ap- plied to the chronic stage which succeeds acute or subacute osteomyelitis. It implies the presence of a sequestrum, more or less detached; of an involvcrum, more or less developed; and of cloacce, usually communicating wuth the surface of the limb by sinuses through which bare bone may be felt. Caries is that condition of bone comparable to an ulcer of the soft parts, there being no actual sequestrum (slough), but only death of bone in molecular masses. It occurs chieflv in tuberculous bone disease V, W.W Fig. 445. — Cortical sequestra following osteo- myelitis of femur. Episcopal Hospital. FicJ. 446. — -Necrosis of hum- erus, showing tubular sequestrum, involucrum, and cloacse. Os- teoporosis above. Episcopal Hos- pital. (p. 439). A sequestrum may be due to necrosis of the superficial cortical layers (Fig. 445), or there may be a total or "tubular" seques- trum (Fig. 446) The superiosteal bone is soft and plastic when newly formed, and possesses great powers of regeneration; if, how- ever, a sequestrum remains beneath it long enough, the involucrum 432 DISEASES OF BONE gradually loses its regenerative powers, and becomes dense and sclerosed; sometimes so dense that the finest steel makes no impres- sion on it. Therefore, it is better, whenever possible, to remove I'"ir.. 447. — Skiagraph of necrosis of til)ia, showing large sequestrum within involuoruni. Ei>isco|>al Hospital. Fig. 448. — Sequestrum of radius ulcerating out eleven months after compound comminuted fracture. Episcopal Hospital. sequestra while the involucrum is still plastic, so that the cavity left Avill be filled up promptly by periosteal proliferation. This stage usually ceases about two or three months after the primary infection. M'J('lil)6l:S OF HONE 433 Tlio jilastic condition of tlu* snhporiosteal hone may he (k'tcnnincd hy sti{'kin<;' a noedk' thr()n first operation, and prompt regen- eration e\en of an entire shaft may he anticipated; but when the femur or humerus is affected, it is better to delay secondary operation until a fairly strong involucrum has formed. This is about two or three months after the onset of the disease; the strength of the involucrum may he determined by skiagraphy, and its total thickness should approximate half that of the normal bone. In some cases sequestra will work themselves loose, and eventually may be discharged spontaneously (Figs. 448 and 449), but this may require many years, and in most cases ulti- mate cure is much accelerated by operation. Sequestrotoniy, as the operation for the removal of sequestra is called, is done under Esmarch anemia : a rubber bandage is applied from the fingers or toes to above the upper limit of disease (Fig. 4.30), thus removing most of the blood from the limb; an Esmarch band is then applied just above the termination of the elastic bandage, which is then removed, leav- ing a bloodless field for operation. This is im- portant because hem- orrhage from the in- volucrum and medulla may be free, and unless the wound is dry it is difficult to distinguish dead from living bone. The limb is then incised, including as many sinuses as possible in the line of incision, or excising the scar of previous 28 Fig. 449. — rhronic osteomyelitis of femur ; age forty-throe years, onset seven years ago. No symptoms for several years until a few weeks ago, when a sequestrum began to work loose; sequestrum extracted through sinus, which promptly healed. Epis- copal Hospital. Fig. 450. — Rubber bandage applied for bloodless opera- tion. The Esmarch band is then applied above the knee, and the rubber bandage is removed from the leg, ex- posing the seat of operation (sequestrotoniy of tibia). Episcopal Hospital. 434 DISEASES OF BONE operation. If the subperiosteal bone is still plastic it is incised with a heavy knife and carefully reflected from the underlying necrotic shaft, whicii is then removed piecemeal or in mass. If a dense involucrum is present, it is searched for cloacae, and the location of sequestra deter- mined, enough of the overlying bone being removed to permit of their removal ; they are more apt to be completely detached from surrounding Fig. 451. — Instruments for operation on bones: 1, wooden mallet; 2, Hey's saw; 3, chisel; 4, osteotome; 5, Volkmann's sharp spoon or bone curette; 6, Jones's gouge; 7, gouge bevelled on its convexity; 8, thumb gouge; 9, gouge forceps; 10, 11, sequestrum forceps; 12, burr. healthy bone than at an earlier stage. When the sequestrum is not completely detached, suspected bone should be removed by gouge and mallet until healthy bone is reached. This is known by the fact that minute blood spots on the bone (Haversian canals) cannot be washed away in living bone, whereas rinsing a chip of dead bone in water will remove all blood from its surface. If the operation is done before sclerosis of the involucrum the cavity. NECROSIS OF BONE 435 if small, may hv allowod to fill with blood-dot, and this prohahly will he coiiviTtcd into hony tissue hy suh-periosteal proliferation (Fif^. 452). When, however, the iinoluerum is dense, any ea\ity left will remain a eavity, unless filled with some substance to stiniulate ossification. Probal)ly the best substance for such purposes is the Fig. 4.52. — Skiagraph showing involucrum of ulna, after removal of sequestra. Note numerous cloacse. Age fourteen years. Epis- copal Hospital. Fig. 453. — Iodoform boiie-wax in cavity of tibia (plombage) . Episcopal Hospital. iodoform bone wax of Mosetig-Moorhof (1903): iodoform, ()0 parts; spermaceti and oil of sesame, each 40 parts. This is heated to 100° C. while being mixed, and again heated to 50° C. before being poured into the bone cavity. Such an operation is termed plombage (Fig. 453). I have used as much as three ounces of this wax at one time 436 DISEASES OF BONE (in a girl of seventeen years), but others have reported symptoms of iodoform poisoning from less quantities. The best results follow when the cavity is dried and sterilized by a hot air blast before pouring in the wax; or by the actual cautery, taking care only to sear and not to char the bone. If this cannot be done, the cavity may be swabbed out with strong antiseptics and dried with sterile gauze. In these chronic cases there is only an attenuated infection. The soft tissues are sutured tight over the wax as it cools, no drainage being employed; and though some of the wax may be discharged eventually through a sinus, convalescence is much less tedious than if no bone filling had been employed. Beck's bismuth paste (p. 484) may be employed in small quantities instead of iodoform bone wax, but is less suitable. In cases where the cavity left is exceedingly large, it is better to resort to the old operation of evidenient, in which the entire anterior and most of the lateral walls of the involucrum Fig. 454. — Acute epiphysitis of left humerus, upper end ; age eight months. Admitted with diag- nosis of scurvy. Temperature rose to 105° F., and at operation epiphysis was found separated. Recovery. Children's Hospital. Fio. 455. — Diagram showing the relation of the upper epiphysis of the humerus to the shoulder- joint. are removed by gouge and mallet, so that only a superficial trough remains representing the posterior wall of the involucrum, thus allowing the soft parts to grow down and across the cavity (Fig. 444), which is packed with gauze. Though healing may take a year or more, the cure eventually is complete. Neuber (1890) tried to hasten recovery by nailing flaps of soft tissues in the gutter left by cvideinent. Acute Epiphysitis. — While in children osteomyelitis is apt to begin and to manifest its greatest intensity in the metaphysis, in infants it occurs almost exclusively in the epiphysis (Fig. 454), and owing to certain special features requires separate mention. The condition frequently is overlooked, from neglect of physical examination; and the closeness of a lesion to a joint (the shoulder and hip are especially liable to the disease) may render it likely to be confused with acute rheumatic arthritis or joint-injury; indeed, as the epiphysis becomes detached from the shaft quite early in the disease, the resemblance to fracture is considerable. Infection of the joint is frequent, owing to TUBEliCl'LOSrS OF HOSE 437 tlie i)()siti()ii of the cjiipliyseal line which even at the shoulder is l)artly iiitra-articiihir (Fig. 4"),")), thus alVordiufj; scarcely any chance for extra-articular drainage. Treatment.^Treatment consists in early incision, exposing the sei)tic focus with curette, and draining the cavity with gauze. If pyarthrosis develops, the joint also should be drained. Deformity from interference with growth, flail-joint, or i)athological luxation (especially at the hip) may follow. Ankylosis is rare. Bone Abscess.— As a result of osteomyelitis a residual abscess (]). SO,")) may form in bone, most frequently in the tibia {Brodies abscess, 1S24). \Vry rarely such an abscess may be the j^rimary lesion, no diffuse osteomyelitis having preceded it; such cases usually are tuberculous. A bone abscess is confined by a dense wall of sclerosed bone, and may remain latent for many years, causing intermittent attacks of pain and limping, and being finally roused to acute stage by trauma or constitutional affection. Diagnosis.— Tlie diagnosis depends on the history, persistent local- ized bone tenderness, and .v-ray examination. Treatment.— The dense wall should be cut away, the pus evacuated, the cavity sterilized, and treated as other bone cavities (p. 435). If the abscess is small, and if its outlines can be well defined by .r-ray examination, it may be possible to excise it in one mass, by cutting through healthy bone on all sides. Fibrous Osteitis.— By this term is understood a condition regarded by all more recent investigators as an inflammatory disease of bone "in which the medullary tissue is replaced by a new formation of con- nective tissue with or without cyst formation." (Bloodgood, 1910.) Its relations to bone cysts and myeloma (p. 445) are not well defined. It occurs in children, affects oftenest the humerus, femur, and tibia, and begins insidiously; in very many cases spontaneous fracture or the deformity resulting from such an unrecognized fracture is what first calls attention to the condition. There may be pain and increase in the size of the bone, but the disease usually is easily dis- tinguished from malignant neoplasms of bone by the long duration of symptoms. Unless the patient is seen for fracture, the swelling and pain, neither very marked, usually exists for a year or niore before the surgeon is consulted. Diagnosis is much aided by the .r-ray, which wall exclude sarcomatous change, and may show cyst formation. Treatment.— The treatment consists in removal of all diseased tissue h\ gouge or curette, the ca^'ity being treated as one following seq nest rot omy. Tuberculosis of Bone.— Tuberculosis rarely affects the diaphyses of long bones, its lesions being confined almost exclusively to the region of the epiphyseal cartilages; but in short bones (hands, feet, vertebra?), diffuse medullary involvement is common. There are good anatomical reasons for this. As noted in Chapter III, tubercle bacilli usually find lodgement in the lymph nodes, and only when 438 DISEASES OF BONE these caseate and rupture do the })acilli escape into the })lood-streain. Infection of bone, therefore, occurs through the blood, the lesion being an infarct or embolus which has successfully passed through the pulmonary capillaries. There are three sets of arteries supplying long bones — one, the main nutrient artery, enters the diaphysis, and branches in both directions; a second enters the metaphysis, while the epiphyseal arteries form the third group; now all these arteries send their terminal branches to the region of the epiphyseal cartilage (which is bloodless), and they do not inosculate with each other. It is in this region, therefore, that bacterial emboli lodge, no matter by which of the three arterial systems they enter the bone. In short bones, however, the main nutrient artery breaks up into small branches almost as soon as it enters the cortex, and tuberculous emboli are arrested in the medulla. It is denied by some that trauma, in creating a locus mi nor is resisi entice, has any influence in determining the localization of tuberculous foci in bone; but clinic- ally it is a well established fact that any site of lessened resistance is prone to invasion by tuberculosis, whether the primary change is traumatic or infectious. According to Ely (1911) the reason that tuberculosis develops in the neighborhood of the epiphyses, and not in other regions (as the brain) which are supplied by end-arteries, is because in the epiphyses the soil is suitable for the growth of tubercle bacilli, while elsewhere it is not (see p. 476). If the tuberculous process begins on the shaft side of the epiphyseal cartilage of a long bone (i. e., in the metaphysis), the resulting lesion resembles a very subacute type of septic osteomyelitis; this condition appears to be more common in Great Britain and on the continent of F.urope than in this country. Its existence was recognized by Volkmann in 1S79, and Stiles has recently (1912) called renewed attention to it. If, however, the tuberculous embolus lodges on the joint side of the epiphyseal cartilage the joint is quickly invaded ; and this often occurs even when the metaphysis is first involved, especially' in joints where the epiphyseal cartilage is largely inside the joint capsule. The affected area undergoes caseation, the bony framework melting away in the centre, while proliferation may take place under the periosteum. In favorable cases the disease may become latent, by encapsulation of the tuberculous focus; or softening may extend, the cold abscess may rupture into a neighboring joint (very frequent in case of long bones), may work its way to the skin surface through a sinuous tract, or may cause gradual expansion of the cortex, with- out rupture (especially in the phalanges). Secondary pyogenic infection may occur, especially after sinus formation, and an osteo- myelitis originally purely pyogenic may become secondarily infected by tuberculosis. For such cases more or less formal operation (seques- trotomy, plombage, evidement), may be required. Joint infection is so very frequent in the case of long bones (especially the femiir, tibia, and humerus) that it is best to study epiphyseal tuberculosis in connection with tuberculosis of joints (p. 476). This is also the TUUERCVLOSHS OF HOSE 439 case ill tlio hoiios of the carpus and tarsus. \'crtcl)ral tuberculosis is considered in Chapter XVI II. In tlie metacarpal bones and piialauges a diffuse tuberculous osteomyelitis follows the arrest of tuberculous emboli, and the lesions are the same in kind as, though running a nuich less acute course than in pyo- genic osteomyelitis. Tuberculous dactyl- itis, as this form is called, occurs almost exclusively in infauts and young children (P'igs. 37 and 45(3) ; it may affect several digits, and may be accompanied by tuberculous bone disease elsewhere. Caries of facial bones in infants usually is tuberculous. Local rest and clean- liness, and general hygienic measures usually cure the- disease, though the finger maj' be deformed from extrusion of sequestra, ankylosis, etc. Caries of the sJxull from tuberculosis is not very rare in adults (Fig. 457). The diagnosis depends on the discovery of tuberculosis Fig. 45G. — Tuljorculous dactjl- itis, early stage; age three years; duration seven months. Epis- copal Hospital. Fig. 457. — Tuberculous caries of skull. Age thirty-nine years. Phthisis for eight or nine years. Present trouble began by swelling like wen, nine months ago. Six months ago this ruptured and has been moist or scabbed even since. Depression in bone palpable. Has another area still in wen stage, fluctuating and red. Episcopal Hospital. elsewhere in the body (notably the lung), on the exclusion of syphilis, and on the chronic and indolent course of the affection. 440 DISEASES OF BONE Syphilis of Bone. — Osseous manifestations of syphilis occur late in the disease, with the exception of fugacious attacks of periosteitis llBllBiUi''^^^ m M ^^^^^^^^^HH^^^ ^^t^ Fig. 458. — Syphilitic dactylitis. Age twenty-eight jears; duration five months. Five years after chancre. Pathological fracture of jthalanx. (See Fig. 459.) Episcopal Hospital. Fig. 459. — Skiagraph of finger shown in Fig 458. (Syphilitic dactylitis.) Note pathological fracture of phalanx. Episcopal Hospital. SYPIIILTS OF HONE 441 in tlic socoiulary stajje. 'V\w losioiis roscmhk' tliose oc-curring in the other infectious granulomas, involving softening and caries, or pro- lilcration and ehurnation. Both processes frcfjuently occur at once in (lill'crt'iit j)arts of the same l)<)ne. In licralltdri/ .sj/phllis the earliest bone-lesions are those in the cranium and phalanges, occurring mostly in young in'ants. In the cranium softening, caries, and su])puration are fre(iuent, with circumferential jxTiosteal o\er-growth, forming the so-called Parrot's nodes (1S79); or mere thinning of the skull from malnutrition and pressure may occur, affecting especially the occipital bone. Caries of the bony nasal septum and l)alate bones also is seen. Si/plilliilc daciiilitis is difficult to distinguish from tuberculous dactvlitis, but usuallv mav be Fig. 460. — Sj-philitic perio.stcitis of left tibia, early stage; duration three months. Hereditary syphilis, patient also having Hutchinson teeth and interstitial kera- titis and marked genu valgum. Age thir- teen years. (See also Figs. 461, 462, and 463.) Orthopaedic Hospital. Fig. 461. — Same patient as Fig. 460: Sabre-blade tibia (left), from photo- graph two years after Fig. 460. Note also syphilitic arthritis of right knee. Orthopaedic Hospital. recognized by the family history, existence of specific lesions else- where, and results of anti-syphilitic remedies; it occurs in acquired as well as in congenital syphilis (Figs. 458 and 459). In tuberculous dactylitis microscopical examination or inoculation may reveal the nature of the process. Constitutional anti-syphilitic treatment of the mother, if the infant is nursing, always should be employed in connection with local treatment. From one to six years of age there are few manifestations of heredi- tary syphilis, but after this period di.sease of the long bones is frequent, especially of the tibise, one or both of which develop a periosteitis, at first more or less well defined (Fig. 400), but later 442 DISEASES OF BONE diffuse and produeino; characteristic " sabre-})lade deformity" (Fig. 461). The bone may be softened early in tlie aft'ection, but later thickening and elongation occur, and the bone is markedly sclerosed (Figs. 402 and 4()3). If the pain does not yield to anti-syphilitic remedies, the bone may be drilled in various places, thus relieving tension; while during the stage of osteoporosis much comfort may be derived from support by braces. The deformity is incural)le. Fig. 462 Fig. 463 Figs. 4G2 and 46.3. — Skiugraphs of syphilitic periosteitis of tibiae, showing "sabre- blade" deformity with hypertrophy and sclerosis of the bones. Age nine years. Epi-scopal Ho.sipital. Osteomyelitis rarely is due to syphilis, but in children gummatous epiphyseal lesions may occur, and cause marked local over-growth (Post, quoted by Nichols, 1907); or by softening and invasion of the joint may produce tuberculous-like arthritis (p. 503). In acquired syphilis the chief bony manifestation of the disease is the periosteal gumma, which may begin with pseudo-inflammatory symptoms, and occasionally breaks externally; under proper anti- syphilitic treatment, however, it is apt to be absorbed, leaving a depressed area on the surface of the bone (calvaria, nasal bones, palate, sternum, tibia) due to dry caries and lacunar resorption, rVMORS OF liOXE 443 witli a tlii(k(Mi(>(l niar<;;in due to periosteal prolitVratioii. It" the process is arrestetl l)e- fore softening of tlie gumma occurs, perios- teal nodes or exostoses may remain instead of dei)ressi()n due to caries. Rarely" a dis- tinct sequestrum forms; this is characteris- tically worm-eaten in appearance and may require many years for exfoliation. In all cases where sinus formation occurs, sec- ondary pyogenic infection is frequent, and sequestrotomy, etc., may be necessary; in other cases constitutional treatment alone often is sufficient to relieve symptoms and arrest the progress of the disease. Pain- ful exostoses may be removed, or eburnated bone (Fig. 464) drilled. TUMORS OF BONE. Fig. 464. — .Syphilitic osteitis causing eburnation of the tarsal bones. Patient had a chancre eighteen years ago, and has pulmonary emphysema which may possibly be an etiological factor in the bone disease. Here may be recognized diseases which comprise what Adami calls blastomatoid conditions (p. 107), as well as true neoplasms of bone. In the former category belong, perhaps, certain of the diseases described as dystrophies of bone, as well as many forms of exostosis, hyperostosis, etc. Among the exostoses (p. 112) several clinical types are recognizable, and deserve short mention here. They are divided into the cartilaginous and fibrous forms. Cartilaginous exostoses are single or multiple out-growths arising from epiphyseal cartil- ages or in the neighborhood of epiphyseal lines; they are most frequent at the upper end of the tibia (Fig. 465) or lower end of the femur (Fig. 466), and may cause trouble by pressure on structures in the popliteal space. Excision is the proper treatment, removing also the portion of bone from which they grow, as recurrence is frequent. One typical aflFection, usually described by the term Multiple Cartilaginous Exostoses (Fig. 467), is thought by some to be a distinct disease; but it seems probable that it may follow any form of chronic inflam- mation, infectious or toxic, whose lesions are located in the bones, and it is certain that it may be associated with, if not caused by, rachitis or syphilis, may affect several Fig. 465. — Cartilaginous exostosis of outer tuberosity of left tibia growing into pop- liteal space. Begun at age of sixteen years, and was re- moved three years later. Re- currence noted first five weeks ago. 444 DISEASES OF BONE in the same family, 1903). It appears seen one case in an patient's attention especially the long epiphyseal lines (p pressure. If this and extend through se^•eral generations fLippert, usually about. the age of pubert}', though I have infant; and it may exist for some years before the is attracted by the out-growths. These affect bones of the extremities, occur mostly at or near . 110), and seldom cause symptoms except rom exists the offending exostoses mav be remo\ed. Fig. 466. — Skiagraph of exostosis of femur spring- ing from region of epiphysis and growing toward diaphysis. Girl, aged sixteen years. Duration two years. Began three months after injury from runner of sled. Orthopaedic Hospital. Fig. 467. — Multiple cartil- aginous exostoses, in a negro girl, aged thirteen years. Children's Hospital. Patients sometimes claim that a certain exostosis has appeared more or less suddenly, or that another has decreased in size. Disturb- ances of gr(n\-th, distortions, subluxations, etc., are frequent in the long bones CBessel-Hagen, 1891). Fibrous exostoses arise either from periosteum or its attached fascia or tendons. Several clinical types are well known, including the ivory-like exostosis of the skull (men- tioned at p. 112); subungual exostosis, found almost solely on the great toe; exostoses of the facial bones, especially the nasal process of the maxilla (leontiasis ossea may commence thus), and the mandible; TUMOh'S OF HOSE 445 and exostoses in connection with tendinou.s infirrti(>n.iit ankyloses. (See Fig. 474.) Orthopaedic Hospital. Symptoms — The pathological changes shown in Fig. 472 may ha\e existed for many months before subjective symptoms arrest the ])atient's attention. Usually the first complaint is of stift'ness in Fig. 474. — Atrophic arthritis. Duration six years. Same patient as in Fig. 47."i. the fingers, worse in the morning and gradually passing away after use; and the patient is dosed for "rheumatism." But on examina- tion this is found not to be real stiffness, but rather weakness, passive ATROPHIC JOINT LESIONS 45: motion being free and often i)ainless. Muscular atrophy is pro- nounced, and often increased the swollen appearance of the joints {V'l'j,. 474). Synovial cIVusion is rare, except from o\er-exertion or trauma; it may he attended i)y considerable pain, but l)oth pain and effusion subside when the joints are put at rest. Joint deformity follows destruction of l)one ends and muscular contraction; but thouiih motion may be limited or even ai)olished by periarticular changes it is free within the range allowed. ^Motion is most limited Fig. 475. — Skiagraph of atrophic arthritis of hands, advanced stage. Woman, aged sixty-five years; duration forty-five years. Marked bone absorption, many subluxa- tions. Two years later skiagraphs showed scarcely any bone left in shafts of meta- carpals. (See Fig. 476.) Episcopal Hospital. in the larger joints; in advanced cases the smaller joints may become flail-like, and the skin covers the phalanges like a wrinkled glove (Figs. 47.3 and 476). Lateral deviation, flexion, or hyperextension of the phalanges may occur, and several dift'erent deformities may exist in the same hand. The only constitutional symptoms are those of slight cachexia and secondary anemia. Prognosis. — The prognosis is gloomy. The disease steadily pro- gresses, and in most cases the patient eventually becomes a helpless cripple. 456 DISEASES OF JOINTS Treatment. — Good feeding and hygiene are reqnired; tlie only favorable results I have seen have been in patients under the care of Pemberton, whose plan of treatment is based on metabolic studies, and is largely dietetic in nature (1913). Medicines are of little value, but Nathan reports increasingly favorable results from thymus extract, in doses of 10 to 20 grains three times daily. Guaiacol carbonate sometimes is useful, in doses of from 5 to 15 grains three times daily, continued for at least a year. This should be combined with potassium iodide and tonics. Rest is necessary when exacerba- tions occur from trauma or over-use; it often is best enforced by use of orthopedic apparatus. Massage, hot baths, baking, etc., and exercise short of fatigue, are of some value. After subsidence of acute symptoms, deformity should be corrected by weight-extension and tenotomy, or even by forcible manipulation, though this is more apt to fracture the bones than overcome periarticular contractures. Fig. 476. — Atrophic arthritis (advanced stage). Same patient as Fig. 475. Episcopal Hospital. Hypertrophic Joint Lesions.— These, as pointed out at p. 550, are not rare as results of attenuated or remote infections; but there are also certain forms of hypertrophic joint disease which seem to be pure disorders of nutrition. In the polyarticular form, "Ileber- den's nodes" (1804) are found; these consist essentially in hyper- trophies of the bases of the distal digital phalanges, often accom- panied by lateral deviation of the terminal phalanx (Fig. 477). The thumb rarely is affected. The monarticular form is of more interest to surgeons. It is the "arthritis deformans" of Volkmann (1882), Schiiller (1900), and Hoffa (190G), the "chronic partial rheumatism" of Charcot (1874), and the "hypertrophic arthritis" of Goldthwait (1905). In this disease the influence of trauma frequently is con- spicuous, hypertrophic lesions developing in a joint injured perhaps many years before (Fig. 402), or in one which constantly is subject to slight injury or strain. Static strain, from imperfectly reduced fracture, or faulty attitudes, often is a cause. The disease affects men more than women, usually those past forty years; and arteriosclerosis seems to be a predisposing factor. Sometimes the affection is called senile arthritis, and when the hip is attacked, it is known as "morbus coxae HYPERTh'OI'llIC JOINT LEGIONS 457 senilis." As ;i matter of fact, liowexcr, the knee is more often aifeeted than the hi|), especially in women; in men the hi]) and spine arc oftener attacked. in the spine the disease is called " sj)ondylitis deformans" (j). (il(i). Tlie earliest path()U)gieal cliange is said to oeenr in the joint car- tihifje; this shows attemj)ts at proliferation, hnt the cartila;e of the base of one condyle to that of the other; the skin is dissected up until the upper border of the patella is exposed and the quadriceps tendon is divided at its insertion into the patella; the knee-joint is acutely flexed, and the intra- articular ligaments are divided. The condyles of the femur being thus cleared, the saw is applied to them and a sec- tion about half an inch thick is remov'ed, not at right angles to the long axis of the femur, but obliquely from without inward, from before backward, and from above downward; in other words, in such a manner that the posterior internal portion of the sawn surface shall be the longest, and the anterior external the shortest. The tibial condyles are then sawed across at right angles to the long axis of the leg, but somewhat bevelled antero-posteriorly so as to correspond to the section of the femur. The tibial con- dyles with the attached pa- tella are then removed in one mass {Ashhurst's operation, 1884). Barely enough of the femur and tibia are removed to allow the limb to come straight; the posterior ligaments always, and the lateral ligaments whenever possible, are left intact. The periarticular tissues are sutured with clironic catgut, and the skin is closed with provision for drainage for twenty-four hours. The limb is dressed in plaster of Paris and immobilization continued for six or ten weeks until union is firm. If complete bony ankylosis (in bad position) is present already, it is sufficient to excise a wedge of bone to restore the axis of the limb (Figs. 487 and 488). In all cases of excision of the knee, Fig. 487. — Ankylosis of knee in flexion, in a girl of twelve years; result of arthrectomy for tuberculosis nine years previously. (See Fig. 4S7.) Episcopal Hospital. 470 DISEASES OF JOINTS the liml) should he sui)iJ()rte(l hy a hraee for a year afterwards. The elhoic is excised through a straight posterior iueision spHtting the triceps muscle near the inner border of the olecranon, and carefidly separating its tendinous expansion from the olecranon. Injury of the ulnar nerve should he avoided; it is most liable to injury just below the level of the joint close to the inner border of the olecranon. After the lateral ligaments have been divided the joint may be luxated. Enough bone is removed (leaving the radial insertion of the biceps) to ensure a false joint being established; a space of at least one inch and a half should ex- ist between the humerus and bones of the forearm, to ensure free motion. The limb is im- mobilized only until the soft parts heal; active use is then encouraged. Return of func- tion depends largely on pre- servation of the periosteum into which the triceps inserts, and its fibrous expansion over the radius. The shoulder is excised through an anterior incision in the hollow between the coracoid and acromion pro- cesses, thus avoiding injury to the branches of the circumflex nerve. The long tendon of the biceps is pushed to one side. The capsule is opened as in shoulder-joint amputa- tions, and the muscles inserted into the tuberosities are divided as there described. Usually the section of the humerus is made through the surgical neck; but it is better to remove more bone from the glenoid than from the humerus, since restoration of function depends largely on the preservation of the muscular insertions in the latter. After-treatment is the same as in excision of the elbow. In all these excisions, it is well, if possible, to open up the line of the old articulation first, by breaking adhesions and sawing across bridges of bone, and then to remo^•e from the bone ends so much as is necessary. Attempts to excise a joint in one block, except by experienced sur- geons, result in the removal of too much or too little bone. Excision of the icrist seldom is required; in most cases an erasion (p. 4; had acute rheumatic arthritis as child and as girl. Orthoptedic Hospital. damaged condition of joints which may persist after one or several attacks of "acute articular rheumatism;" on such a joint may be grafted, as on to any joint or set of joints whose resistance is below par, dystrophic lesions. I believe Fig. 491 represents such a condition. Still's Disease (1897), a chronic polyarticular affection of young childhood, resembling atrophic arthritis in many respects, and accom- panied ])y enlargement of the lymph nodes and spleen, and involve- ment of the cervical spine, probably belongs among the cryptogenous infections. So does the tuherculoiis rheumatism of Poncet (1903), which is a subacute polyarticular infection, somewhat resembling in onset "acute articular rheumatism," but probably due to endogenous toxins of tubercle bacilli (Figs. 492 and 493). In this group of crypt- ogenous infections also belong certain cases of arthritis which cease to VNKXOWX INFKCTIOXS OF TlIK JOINTS 475 tr()ul)k' till" palii'iit wlii'ii Uv is curod t)t" .sonic source ot" inl'cctioii which iiijiy have been ncf!;lecte(l for yciirs; such are dental caries, pyorriiea Fi(i. 492. — Tul)ciX'iilous rhcuinatisni in a girl of fi\-e .\-e:us. Acute onset in left ankle, some weeks after an attack of scarlatina. Six months later left knee, wrist, and shoulder liecame similarly affected; reacted to tuberculin. Photographed one year after onset. (See Fig. 493.) " Orthopa;dic Hospital. Fio. 493. — Patient shown in Fig. 492, one year later. Normal extension in left rist. Knee still in plaster of Paris, and four years later not yet quiet. Orthopsedic .•*„! wrist. Hospital. alveolaris; sinus diseases; affections of the tonsils; empyema thoracis (Fig. 494); affections of the lungs (here belongs pidmonary osteo- 476 DISEASES OF BONE arthropathy), intestines, appendix; genito-iirinary diseases in both sexes, especially chronic semino-vesiculitis or prostatitis in the male, and cervical lacerations in the female, etc. Cases of joint disease concerned with one or more of the abo^■e infections are constantly being seen, and are recognized by intelligent physicians; and some remarkable results obtained by cure of the primary infection have been reported by Marsh, Goldthwait, and others. In chronic rheumatoid conditions always look for a source of infection. Fig. 494. — Pulmonary osteoarthropathy. Clubbed fingers four years after operation for empyema (unhealed; . Age ten years. Children's Hospital. Tuberculosis of Joints.' — Pathology. — In tuberculous arthritis the primary lesion in almost all cases, especially in children, is in the adjacent bone, and the synovial membrane lining the joint cavity is invaded only secondarily. This was first definitely shown by Nichols, of Boston, in 1898. The bacilli reach the bone ends through the blood-stream, presumably from a preexisting focus in the bronchial or mesenteric lymph nodes; and they lodge in the region of the epiphy- seal cartilage rather than in the diaphysis of the bone for the ana- tomical reasons stated at p. 438. The di.sease begins on one side or other of the epiphyseal cartilage. An additional, and perhaps a better reason for this localization of the bacilli is suggested by Ely (1911): he recalls the well known fact that tubercle bacilli flourish where red marrow exists (as in the epiphyses of growing bones), whereas bone which contains yellow marrow (adult bones throughout, and the diaphyses of juvenile bones) is almo.st immune to tuberculous invasion; he also suggests that the immunity of cartilage and fascia to tuberculous invasion is due to the fact that only in connective tissues which have epithelial, epithelioid, or lymphoid cells, do tubercle bacilli find a suitable soil for development, and that in this way the marked affinity of tuberculosis for synovial membrane is to be ex- plained. This theory of Ely's also explains why primary synovial tuberculosis is so much less unusual in adults than in children, since ^The tuberculous nature of these diseases was first clearly demonstrated by Volkmann, in a classical paper published in 1879. PATHOLOGY OF TUBERCULOUS ARTHRITIS 477 the hones of tlie former do not aiford a suitahle soil for tlie develop- ment of tuberculosis, owing to the absence of red marrow. In tuberculosis of an ei)iphysis the lesion exists in th(! marrow, the cells of this structure being grouped around the invading bacilli in the form of histological tubercles; the bony trabeculne are then destroyed, the centre of the tuberculous focus undergoes caseation, and caries of the bone is said to exist; if actual liquefaction occurs a cold absrcs's of bone is formed. The entire bone end is the seat of a rarefying osteitis, the bony trabecuhe be ng much decreased in size and strength, while the marrow spaces are increased. Formation of sequestra is rather unusual ; when found they are small, and tyi)ic- ally worm-eaten in appearance. Often there is a zone of sclerosed bone immediately around the sequestrum or the central caseous area, while outside of the sclerotic bone the rarefying osteitis, above described, continues. Caries Sicca is a term used by Volkmann (1867) to describe a rare form of joint disease now recognized as tuberculous, which is seen oftenest in the shoulder and in which gradual, quiet, fibrous ankylosis occurs, without swelling or other evidences typical of tuberculous arthritis. The articular cartilage resists for a long time invasion by the spreading tuberculous process, and when the joint finally is entered it is more often at the site of attachment of the capsule than in the centre of the articular cartilage. But as the disease progresses the articular cartilage is gradually covered in by the tuberculous granulation tissue or "pannus," and is perforated in numerous places, giving (Fig. 495) it a typical sieve-like (Volk- mann, 1882) or "pepper-pot" ap- pearance; and in advanced cases the cartilage may be entirely de- stroyed. Before actual tuberculous inva- sion of the joint cavity, there may be slight serous synovitis with effusion, from irritation due to the focus in the neighboring bone end. When the synovia has once been invaded, or in the rare cases of primary synovial disease, the tuber- culous process spreads rapidly throughout the joint, attacking and perhaps destro}dng the ligaments, reaching out along adjacent tendon sheaths and bursse, and causing a pulpy, gelatinous hyperplasia of all the serous tissues attacked (gelatinous arthritis, Ashhurst, 1871). Usually there is very little eflfusion, though "tuberculous hydrops" occasionally occurs (Fig. 496). Either by condensation of fibrinous Fiu. 495. — Head and neck of femur excised for tuberculosis. Note "pepper- pot" appearance of cartilage covering head of femur; pathological fracture of neck: and small sequestrum below. Children's Hos- pital. 478 DISEASES OF JOINTS flakes, or by detachment of the tips of the villous synovial fringes, so-called "rice-bodies" or "melon-seed bodies" may develop in tuber- culous joints. By most authorities these are regarded as highly characteristic of the tuberculous nature of the joint lesions: tubercle bacilli frequently have been found within the rice-bodies, and their inoculation into susceptible animals causes generalized tuberculosis. If the tuberculous process extends to the skin surface, and a cold abscess of bone discharges itself through a sinus, secondary infection with pyogenic cocci is extremely apt to occur. Before such seconrlary invasion the walls of a sinus communicating with a tuberculous focus are not themselves the seat of tuberculosis; but when sec- ondary infection is present the connec- tive tissue which forms the walls of such a sinus are studded with tubercles (Ely, 1911). Secondary invasion with pyogenic cocci may occur through the blood-stream before any sinus forms; such a complication is apt to hasten the disintegrating process and encourage formation of sinuses. Healing occurs by the encapsulation of the tu})erculous focus or its replacement i)y fibrous tissue. If the joint cavity has been invaded this implies more or less firm fibrous ankylosis. In most cases the tuberculous process merely becomes latent, and is prone to become active again if the joint is subjected to unusual strain, or if the general health becomes impaired, particularly })y the development of pulmonary tuberculosis. Clinical Course and Symptoms. — Joint tuberculosis is much more frequent in children than in adults, arising especially during the first decade of life. The spinal joints are those most often affected; the knee and hip come next in order of frequency; while the joints of the i^ot, elbow, and wrist are more frequently diseased than the shoulder. In about one-third of the ca.ses in children a history of traumatism can be obtained, two or three weeks previous to the onset of joint symptoms; and this generally is regarded as having a distinct etiological relation to the development of the disease. But it mu.st be remembered that nearly all children sustain slight joint injuries, yet comparatively few develop tuberculous arthritis; so that it is necessary to assume a predisposition to tuberculosis and the existence of a primary focus elsewhere in the body. The injury which precedes the tuberculous joint symptoms rarely is severe; fractures scarcely ever are followed by tuberculosis, and fractures rc-iilotis h\-drop.s Fk;. 49G.— Till; of right knee. Age eight year.s. Duration six months. For persist- ence of .symptoms, excision of knee was done five years later. (Dr. Dickson's case.) OrthopEedic Hospital. SYMI'TOMS OF TLHKRCVLOVS AinHRITIS 479 in tlu' tuhiTculous heal normally. Two exjjlanations are t)flVrc(l for this: one is that the more severe injury arouses better defensive action on the part of the patient ; the other is that sexcre lesions recjuire careful and i)rolonji-c(l treatment, and healinj;, therefore, is more ai)t to oceur than after a trivial injury which often is nejijlected. Amonj; the earliest subjective symptoms of tuberculous arthritis are disability and pain. The joint is used less, the joint is "favored," and it fjives evidence of bein^ more easily tired than the normal joint. StilVness ])resent on getting out of bed in the morning may wear away during the day; but toward evening the joint again becomes disabled, and this is evidenced by slight limp, and com])laints of pain. Pain may be almost absent except when the joint is used; but frequently a joint which is painless when the child is awake will trouble it at night, causing restlessness, and on falling asleep and relaxing its muscles the child will experience "starting ])ains" which will rouse it momentarily from sleep with a "night-cry." Instead of pain being felt at the diseased joint, it may be referred to the peripheral distribution of the nerve supplying the joint: thus in tuberculous spondylitis pain frequently is present in the epigastrium (intercostal nerves), and in tuberculosis of the hip pain is referred to the knee (obturator nerve). Examination of the diseased joint at this early stage shows slight but persistent muscular spasm. The muscles surrounding a joint are supplied by the same nerve that supplies the joint, and irritation of the joint causes reflex irritation of the adjacent muscles (Hilton's law, 1877). The joint may be held absolutely rigid by the patient, but in the earliest stages the most that can be detected is limitation of motion in all directions: there is neither full extension, flexion, abduction, adduction, nor rotation; and forcing any of these motions causes pain. Comparison with movements of the corresponding unaffected joint is imperative. The joint is held in the most com- fortable position and is consistently protected by the patient: a sore wrist or elbow is supported by the other hand, and if the hip or knee is involved the sound foot may be put under the ankle of the diseased limb and be used as a splint to prevent motion in the painful joint. There is tenderness to palpation directly over the joint, and per- sistent tenderness of a bone end with evidences of articular irritation is a valuable sign, l^nless the disease is advanced, or primarily synovial in origin, there is rarely much thickening of the capsule or synovial effusion. In superficial joints (knee, elbow, ankle) more or less heat usually is appreciable, but in the hip this seldom can })e detected. ^Muscular atrophy, an evidence of disuse, is a valuable confirmatory sign of tuberculous arthritis; in early stages it sometimes can be detected only by measurement, but in later stages, where articular thickening is present and accentuates the atrophy, it is apparent at a glance (Fig. 523). With these local signs there is seldom much constitutional reaction. 480 DISEASES OF JOINTS The temperature may be raised 1° or 2° in the evening, and loss of appetite and malaise may be present; but there is no acute inflamma- tory state such as is seen in cases of septic arthritis. As the disease progresses, the joint thickening increases, being of a doughy, boggy consistency, and t\-pically spindle-shaped in outline. The skin is pallid, and the affection well deserves the name "white swelling" which has been applied to it for so many years. Spastic contraction of the surrounding muscles passes into true contractures, which will maintain deformity even if ankylosis is absent. Progres- sive joint disintegration may lead to partial or complete dislocation; and this usually is attended by relief from pain. Finally, by rupture of cold abscesses, sinuses may develop, and usually this complication is quickly followed by secondary infection, resulting in hectic fever, and the gradual but progressive decline of the patient's general health. Diagnosis. — Symptoms of subacute arthritis in a child, from no apparent cause, or following slight injury, and without marked constitutional reaction, but persisting in spite of temporary rest, always should excite a suspicion of tuberculosis. This suspicion is strengthened by a family history of tuberculosis, either pulmonary or osseous, and is made nearly positive if there is persistent elevation of temperature of 1° or 2°, if the tuberculin tests (p. SI) are posi- tive, and if there is no leukocj-tosis. Skiagraphic examination rarely will reveal any bony focus so early in the disease as to be of much value in doubtful cases, but a squaring of the epiphyses, particularly at the knee, is regarded as characteristic of tuberculosis. A sprain will cease to cause acute symptoms if the joint is put to rest for two or three weeks; but a tuberculous arthritis always will be roused to activity if joint function is resumed in so short a time. A septic arthritis is more violent in its onset, is attended by much more constitutional disturbance, and progresses to early suppuration and joint disintegration; its course is run in days and weeks, while that of a tuberculous arthritis extends over months and years. Acute rheumatic arthritis is in most cases a polyarticular affection, is char- acterized by high temperature, cardiac or pleural complications, h;v'perleukocytosis, and marked local inflammatory reaction. It is rare in young children. In syphilitic arthritis other signs of syphilis nearly always can be detected. A positive diagnosis of tuberculosis always can be made if tubercle bacilli can be found in the synovial membrane, rice-bodies, joint- fluid, etc., or if inoculation with these substances causes tuberculosis in a susceptible animal. Prognosis. — The most favorable cases are those of apparent osseous origin in children, in which efficient treatment is instituted before evidences of invasion of the synovia are demonstrable, and in which the symptoms are so slight as scarcely to warrant a positive diagnosis. These are the cases in which patients recover with joints which are to all intents and purposes normal. After joint invasion is once TREATMENT OF TUBERCULOUS ARTHRITIS 481 tlc'iiioiistrahle, and in cases primarily synovial, the most that can be hoped for is recovery with more or less impairment of motion; and the more firm the ankylosis the less apt will the ])atient be to have recurrence of the disease. After secondary infection the prof;;nosis is t^loomier both as to function and life; and in adults all forms of tuberculous arthritis are much more serious than in children. In general terms it may be stated that from one-third to one-half of j)atients with tuberculous arthritis die as a result of their joint lesions; few indeed as a direct consequence (then mostly from hectic, amyloid degeneration of the viscera, etc.), but many from tuberculous menin- gitis, phthisis, or some intercurrent malady from which healthier persons would have recovered. In cases ending in apparent recovery, which often is merely latency of the tuberculous process, the course of treatment must last from one to five years or longer; and other patients must continue treatment until death removes them from the surgeon's care. Treatment. — The coiistitutional treatment of surgical tuberculosis was discussed at p. 82; its value in tuberculous arthritis is inesti- mable, and never should be forgotten. The most efficient local treat- ment frequently is powerless to check the disease; and sometimes constitutional treatment alone is able to restore a patient to health. The surgeon must not overlook the fact that it is better to have a healthy body with a stiff or deformed joint, than to have a straight and comely joint without a body capable of sustaining life. If the general health is good, joint function can be restored subsequently by an orthopedic operation. Every hospital should have an open air ward or at least a porch available for tuberculous joint cases, where the advantages of constitutional and local treatment may be combined for those most requiring such care. Local treatment may be summed up almost in one word: Rest. It is not known definitely how this acts, but a plausible theory is suggested by Ely (1911): he contends that cure is effected by abolish- ing joint function, because thus both red marrow and synovia become atrophic and in the case of ankylosis entirely disappear; and where they are not, tubercle bacilli cannot exist. There are two chief methods by which joint rest is obtained: fixation and traction. Fixation is secured by the use of splints, plaster cases, braces, etc., the sole object being to abolish motion at the diseased joint as effectually as possible; this not only relieves pain, but has direct influence in checking the tuberculous process. By traction is understood not so much actual extension on the limb sufficient to pull the joint surfaces apart, as cessation of weight- bearing and relief of pressure: it acts by relieving pain and securing rest, but also prevents deformity which is prone to occur when the weight of the bod}' is borne on the softened bone ends. Traction is applied chiefly to the knee, hip, and spine; fixation alone usually is sufficient for the upper extremity. Whenever possible in the spine and lower extremity the advantages 31 482 DISEASES OF JOINTS of fixation and traction should be combined. This is best accomplished by bed-treatment, so long as acute symptoms persist, regardless of the stage of the disease. Recumbency at once removes the weight Fig. 497. — Bradford frame. See text. of the body from the diseased joints, and fixation is much more readily secured. In children, the use of a Bradford frame (1890) (Fig. 497) to which the body is strapped, provides fixation for spine, hip, or Fig. 498. — On the roof garden of the Orthoptedic Hospital. Showing Bradford frames with head and foot extension. knee, in the most efficient manner. This frame is made of gas-pipe, and is covered with tightly stretched canvas; it should be a little longer than the patient and as wide as from one armpit to the other. The child is fastened to it by a broad canvas apron covering chest TREATMENT OF Tl' liERCULOUS ARTIllilTlS 483 and alxloiiuMi, or hy straps crossing tlu' slionldcrs.' Tho franir thns hecomi's a |)art of the child, and the two together can hv carried al)o\it from room to room, or from ward to roof garden (Fig. 4!)N), thns preventing the painfnl and harmfnl joint-movements necessitated hy carrying the child in the arms or transferring it to a stretdier and hack again to the bed. Weight-extension nsually is a desiral)Ie adjnxant in secnring joint fixation, and is the most effectnal method of ()\(Tcoming pain and nuiscnhir sj)asm, to which hitter factor deformity in tiie earliest stages is (hie. Weight-extension always should be applied in the axis of the deformity (Fig. 512), and as spasm lessens the direction of the extension can })e gradually changed until the normal ])osition is secured. (Ireat care must he exercised during recumhent treatment to keep the foot at a right angle with the leg, preventing the development of talipes equimis. When all symptoms of arthritis (limitation of motion from si)asm, l^ain, fever, etc.) have been absent for a month or more, recumbent treatment may be discontimied. This stage is reached after two to six months in cases coming under observation in the early stages of the disease. Tf local treatment (fixation and traction) are now recklessly discontimied in the erroneous idea that the joint is cured, and if the patient is allowed to resume joint function, it will be only a few weeks before all symptoms of arthritis return, and possibly in aggravated form. It is absolutely imperative to guard the joint against injury and strain by continuing for a long period fixation or traction, or })otli, during ambulatory treatment. By the use of plaster of Paris cases, braces, crutches, etc., both fixation and traction (in modified forms) can be continued; and this should be done until, by allowing gradual return of function (first limited motion, then weight-bearing), the surgeon proves that the joint lesion has become .so thoroughly encapsulated as not to be liable to cause recrudescence of the disease. This period of ambulatory after-treatment extends always through several months, usually through a year or more, and often for many years. Only by making haste slowly can permanent good results be achieved. If there is any reason (there are few good reasons) why recumbent treatment is impossible when the patient first is seen, ambulatory treatment with fixation and traction may be employed from the start; but this is apt to promote ankylosis, and deformity is very difficult to prevent. ^loreover, in many cases the symptoms are so acute that rest in bed is an absolute necessity. Yet I believe with Coudray (1911), that in no case should a manifest tendency toward ankylosis be hindered; the joint should be kept in good position, but attempts to preser^'e motion are extremely apt to keep the disease active. The surest and most lasting cures are those which follow ankylosis. Treatment of Cold Abscesses. — If the joint be put at rest, and the patient kept in the open air, the threatening abscess may cease to ^ G. G. Davis uses also an uppei- frame, well padded and moulded to the body, to hold the child against the lower frame. 484 DISEASES OF JOINTS enlarge, and in not a few cases gradually will disappear. Hence these conservative measures should be given full trial. If the abscess continues to enlarge, and threatens to approach the skin, with the consequent danger of infection from the skin cocci, even before spontaneous rupture makes such an infection sure, I think it is best to expose the abscess wall by careful dissection tlirough overlying healthy tissues, to incise the abscess, evacuate its contents, and wipe the abscess cavity gently but thoroughly with iodoform gauze. I cannot see that anything is to be gained by curetting the walls of the abscess cavity, nor by attempts to "excise the sac," which in many cases is an impossibility. The incision to reach the abscess is sutured in layers, without drainage. Children should be etherized, but in adults, local anesthesia is sufficient. In most cases (fifty-one out of sixty, according to Starr, 1907), the incision heals without breaking down at any point, and in only a very few cases does the abscess refill and require a second evacuation. It is dangerous to leave a cold abscess to itself until the overlying skin has become adherent and reddened, since secondary infection from skin cocci is frequent, and rapid joint disintegration, hectic, amyloid disease, etc., follow; and it is still more dangerous to open a cold abscess without perfectly aseptic technique, or to drain it by tube or gauze after incision, or to allow it to discharge itself spontaneously. But sometimes the patient is not seen until spontaneous rupture threatens, and secondary infection already is present. Under such circumstances the abscess should be evacuated by a small incision where it is pointing, but should not be drained ; the puncture should be occluded with aseptic gauze, and in many cases little or no subsequent discharge will occur, the "hot" will gradually resume its character of "cold" abscess, and eventually may be absorbed. Thus the formation of sinuses and prolonged suppuration may be prevented. Aspiration of a cold abscess is inferior to formal incision, because it cannot be done satisfactorily until the ])ii- i> very close to the surface and unless it is very fluid. A certain iiiuiilx.T of cures, however, will follow aspiration and injection of a 10 per cent, iodoform-glycerin emulsion. Treatment of Sinuses. — In tuberculous arthritis sinuses nearly invariably are an indication of secondary infection: if no secondary infection is present (a fact which bacteriological investigation will demonstrate), they usually will heal under rest and constitutional treatment. I have had exceptionally good results from helio- therapy: the sinuses are exposed to direct sunlight, beginning with periods of five minutes twice daily, and increasing the length of the exposures as rapidly as possible without producing sunburn. If the sinuses fail to heal, and if discharge of pus is not profuse, they should be filled with the bismuth paste of Beck (1905): one part of bismuth subnitrate (arsenic free) to two parts of sterile amber vaselin. This is heated in a water bath until fluid, and is injected into the sinuses by a syringe which after being boiled, is rinsed in alcohol and TREATMENT OF TUBERCULOUS ARTHRITIS 4S5 ;ill()\v(>(l to (Irv before it is filled with the li(iui(l paste. The sinuses ;ire filled as full as i)(>ssil)le. A skiaj,Tai)li, made after distending the sinuses with this paste, will show their ori.uiu and raniifieations (Fig. 499). If pus should he dammed uj) hehind the i)ast(>. the iuereased Fig 499 —Skiagraph of tubertulous arthritis of left hip, with sinus discharging on outer surface of thigh; sinus has been distended with Beck's bismuth paste. Boy aged ten years- coxalgia for six years. Abscess punctured three months before skiagraph was made, because it was pointing and because there was secondary infection from skin cocci. Orthopaedic Hospital. local heat will cause the paste to melt, and it will be extruded from the sinus spontaneously. The mode of action of bismuth paste is not certainly known, but it causes marked improvement, the dis- charge diminishing and the sinuses often closing in a comparatively short time. If a firmer injection mass is desired, the following formula 486 DISEASES OF JOINTS (Beck's paste No. II) may be employed: Bismuth subnitrate (arsenic free), 30 parts; amber vaseliii, 50 parts; paraffin, 10 parts. Or Mosetig- Moorhof's iodoform })one-wax may be used (p. 435). Bismuth poisoning has been observed in a few instances, so not more than four or six oimces of Beck's paste should be employed in a child. If profuse suppuration persists in spite of conservative measures, it is probable that a sequestrum is present, and this may be removed by curette or gouge. Formal operation in children rarely is advisable. Injections of alcoholic solutions of iodin (2 to 10 per cent.) are useful in overcoming secondary infection. Operative Treatment in Tuberculous Arthritis. — It might be thought that early excision of the diseased area would abort the disease, but unfortunately it scarcely ever is possible to locate by skiagraphy or otherwise an extra-articular focus; nor would what might be con- sidered total extirpation of the focus amount to much more than removal of the centre of an area infected far beyond what is indicated by gross appearances. When once the joint itself is involved, only a formal excision could remove all the disease, and in children such an operation, which implies removal of the epiphyses, is productive of such marked deformity and disability as to be generally condemned by intelligent surgeons. Moreover, in children, the results of con- servative treatment thoroughly carried out, as outlined above, are so satisfactory, that operation presents no advantages in the early stag&s of the disease. In adults, on the other hand, the results of conservative treatment have proved so disheartening, chiefly through their inability to endure confinement to bed, and their tendency to develop phthisis, that joint excision or even amputation is the accepted form of treatment. Ely (1911) claims that an excision which will produce ankylosis and thus permanently abolish joint function is all that is necessary to effect a cure; he asserts that it matters not how little bone is removed, nor how much tuberculous material is left, so long as ankylosis is obtained, as this in itself will cause dis- appearance of synovia, which is the joint tissue on which in adults tubercle bacilli almost solely subsist. But hitherto it has been the habit of surgeons to remove as much diseased tissue as possible. In chil- dren, excisions, if done, should be limited to the epiphyses of the bones, the epiphyseal cartilages being rigorously respected, and any focus in the metaphysis should be evacuated by the curette through a perforation of the epiphyseal cartilage, and not by sawing off the bone end until all diseased tissue disappears. Arthredomy or erasion of joints, adapted especially to the knee, was introduced by Wright, of Manchester (1881), and in this country by J. Ashhurst, Jr. (1889), as a substitute for excision in children; it aims to remove all the diseased soft tissues (synovia, ligaments, cartilages) without invading the bones; and may be employed for the purpose of effecting ankylosis when conservative measures fail to secure subsidence of symptomis. Like excision, there is nothing specific in its action; it is merely a method of joint disinfection. THE ATM EST OF TLBEliCV LOl'S AMOIJJSJS 487 Trcaiinenf of Anki/losis from Tiihrmilon.s- Arllirifl.s.- \s lias already been indicated, ankylosis t'ollowiiif; tuherculous arthritis often inii)lies merely a latency of the disease, though no doubt definitive cure sometimes occurs. But owing to the frequency with which slight trauma, even many years after ankylosis has occurred, may rouse the dormant lesion into activity, the surgeon should be extremely cautious in efforts to restore joint motion. If ankylosis has occurred in good position, especially in the joints of the lower extremity, no Fig. .jOO. — Ankylosis of hip from old coxalgia, age thirteen years. Ortho- paedic Hospital. Fig. 501. — Same patient as Fig. 500; one year after subtrochanteric osteotomy of femur. Orthopsedic Hospital. treatment should be adopted, as a rule. For deformity at the hip, subtrochanteric osteotomy (p. 468) is the best treatment, as it divides the bone where healthy (just below the lesser trochanter), and there is very little risk of rousing the old disease, especially if the bone section is made with a saw instead of by osteotome and mallet. A puncture is made about two inches below the great trochanter, on the outer side of the femur, with Adams's knife; this is passed directly to the bone, and is then carried across its anterior surface, and along this knife as a guide, Adams's saw is passed; the knife 488 DISEASES OF JOINTS is then withdrawn, and the femur is divided by very gentle sawing. The limb is then brought into a position of abduction and nearly full extension (Figs. 500 and 501). Tenotomy of the adductors may be necessary to secure abduction. The limb is then fixed in this position in plaster of Paris, and is treated as a recent fracture. At the knee, formal excision (p. 469) usually will secure a useful and straight limb, though still ankylosed; attempts at arthroplasty in tuberculous knees are to be condemned. An ankylosed elbow causes great disability even "if ankylosis has occurred at the best possible angle, and excision may properly be done with the aim of restoring motion. The same is true of the shoulder. Fig. 502. — SkiaRraph of tulx-rculosis of left hii>joint. Boy, aged five years, duration five months. Note al)duction and flexion of thigh; absorption of head of femur and involvement of acetabulum. Orthopiedic Hospital. Tuberculosis of the Hip. — Pathology — The primary lesion is in the neck or head of the femur in most cases, but occasionally the acetabulum or synovia is first involved. Acetabular and synovial disease are intra-articular from the beginning; and a femoral lesion very soon penetrates the joint, the epiphysis of the head being intra- articular. Thus in all cases invasion of synovia occurs early, and in many the acetabulum remains healthy for only a short period. There is marked rarefaction of the bone, nearly all calcareous matter dis- appearing; the skiagraphic picture (Fig. 502) is not unlike that of round-celled sarcoma of bone in the total obliteration of all land- TUJJERCrLOSIS OF THE HI!' 489 marks. If wci^flit-beariii^ is contimicd, the acctiiimliiiii may he enlarged iij)\v;ir(l and hackward (" waiidcriiij:; acctahuliim"), and patlioloj^ical luxation may occur; if this is an early symptom in cases in which wci^dit-hcariuj; lias not been allowed, it generally is due to rupture of the cai)sule from intra-articular effusion. The head of the femur may become very much altered in shape, or entirely absorbed; and when secondary pyoj^enic infection is present, patholof^ical fracture of the neck is not very rare (Fig. 495). The best result in such cases is firm ankylosis (Fig. .'03). Fig. 503. — ."t-kiagraijli of ankylosis of right hip following tuberculosis. Girl, aged thirteen years; coxalgia at nine years: no symptoms for two years; healed sinus present in groin. Note obliquely contracted pelvis. Orthopaedic Hospital. Symptoms and Clinical Course. — When early symptoms of tuber- culous joint disease (p. 479) point to the hip, the patient should be attentively examined after removal of all clothing from the waist down. Nearly 90 per cent, of cases are in children under ten years of age. First the gait (bare-footed) should be studied : usually a slight limp will be noted; and in the early stages the thigh is held in slight flexion and abduction, causing flattening of the buttock and obliteration of the gluteal fold on the affected side (Fig. 504). The patient is then laid flat on his back on a firm table: measurements from the navel to the malleoli may show apparent lengthening of the affected extremity; this is due to its abduction, but if the healthy limb is placed in a 490 DISEASES OF JOINTS similar degree of abduction the discreijancy will disappear. Unless there is marked bone deformation or dislocation there can be no actual change in the length of the Fig. 504. — Tuberculosis of the left hip. First stage: flexion and abduc- tion; flattening of buttock and oblit- eration of the gluteal fold. Age five years; duration two months. Ortho- pcedic Hospital. joint limbs. Examination usually is best begun by testing the motions of the normal limb, making all the tests with extreme gentleness, and aiming to gain the child's confidence. Usually the affected thigh is kept slightly flexed (Pig. 505), and when an at- tempt is made to bring it out straight, the lumbar spine rises from the table (Fig. 50()) because the hip is held rigidly in flexion, and motion is transferred to the spine. First rotate the lower extremity gently to and fro in its own axis, comparing the motion in the two limbs; there will be little or at least limited rota- tion on the diseased side, and it will be painful. Then try abduction of the thigh, still keeping the limb as fully extended as possible; on the diseased side abduction usually is markedly limited by the muscular spasm. The range of flexion is next investigated, first, by bringing the sound thigh up against the abdo- men, and then comparing this with this usually is somewhat limited. flexion in the diseased but not so markedly as rotation and abduction. Next, abduction with the thigh flexed to a right ang'e may be tested; this is always Fig. 505. — Tuberculosis of right hip for nine months. Age three years. The hip is held in a flexed position by muscular spasm, and the lumbar spine lies flat on the table. (See Fig. 506.) OrthopEedic Hospital. much decreased on the diseased side. Then the child is turned over on its stomach, and the range of hyperextension is tested in each hip by raising the knee from the table; this movement always is TUBERCULOSIS OF Till': H 1 1' 491 limited Dii the diseased side, and ulierc marked llexioii det'ormity is present, it is manifestly unnecessary to test hyperextension. 11' any of tliese motions are persistently, even if only very slightly Fig. o()(J. — 'rulicrciilosis of iiKht \\\\^ (sec Fig. 505), showing archiiii; of luniJjar spine when attoinpt is iiiadc to hriiifx tlic knee down on the tal)le. Motion occurs in the hnnl)ar spine, not in tlie hip-joint. Ortlioptedic Hospital. limited, and if there is a history typical of the onset of tuberculous arthritis, the diagnosis may he considered established; and if an exami- FiG. 507. — Deformity, following tuber- culosis of hip: adduction and shortening (six inches). Age sixteen years; onset of disease at three years; healed sinuses. No symptoms for the last eight years. Orthopaedic Hospital. Fig. 508. — Extreme exterior rotation following tuberculosis of hip. Age twelve years. Duration four years; sinuses still open. (Dr. Alexander's case.) Episcopal Hospital. nation such as above indicated were systematically made by the physician first called to attend the patient, and if proper treatment were instituted, valuable time would be saved. Only too frequently 492 DISEASES OF JOINTS the family physician makes no physical examination at all, or only a partial one, hampered by the patient's clothing; and treatment for a sprain or for rheumatism is pre- scribed, when a very little more trouble would have enabled a correct diagnosis to be made. In the rare cases where the signs are so slight as to render a positive diagnosis hazardous, the surgeon will consult his own and the patient's interests much better by enjoining recumbent treatment for a week or two, than by making light of the malady. At a later stage of the disease, the early deformity of abduction is replaced l)y adduction, possibly owing to atrophy of the iliopsoas which lies closest to the joint, and the unapposed action of the adductors. In efforts to walk the patient has to bring the lower extremities parallel, and as the dis- eased limb is fixed in adduction, the healthy limb must be abducted to correspond; this causes a descent of the pelvis on the unaffected side, and apparent shortening of the diseased extremity. But if the healthy limb is placed in a similar attitude of adduction, the measurements will be found the same, unless bone destruction or dislocation is present. The deformity of flexion and adduction, in this which is called the second stage of "coxalgia," may be due in part to intra-articular Fig. 509. — Cold abscess of left thigh, from tuberculosis of hip. Sequestrum discharged later. Age four years; duration three years. Orthopaedic Hospital Fig. SlO.^GIuteal abscess in coxalgia. (Dr. Hodge's case.) Children's Hospital. changes, but most of it is due to muscular contractures which may be overcome by joint fixation and traction. TUBERCULOSIS OF Till': /III' 493 At a still later stage of the disease the patient may come under observation with cold abscess or simises, and with ankylosis in almost any jjosition fFij^s. '){)7 and 508), or with patholoj^dcal luxation. Told abscesses and sinuses usually are in direct comnuuiication with the joint cavity, but occasionally are due to extra-articular perforation of the l)one. The abscess may ])()int at any part of the thifi:h, but Fig. 511. — Adductor ahscess in coxalfria. Ago six years. C'oxalgia for one j'ear. Abscess for four weeks. Orthopaedic Hospital. the most frequent site is on the outer side (Fig. 509); or a gluteal abscess (Fig. 510) may occur, usually from perforation of the poste- rior capsule. x\bscesses or sinuses in the adductor region (Fig. 511) usually are an eA'idence that the acetabulum is involved, as, accord- ing to Vincent (1895) is the occurrence of adduction as the primary deformitv. Fig. 512. — Bed extension for coxalgia with flexion deformity. Note the high cradle to keep the bed-clothes ofT the foot. Episcopal Hospital. Diagnosis. — Not every case of arthritis of the hip is tuberculous, even io children, and where doubt exists as to the etiological factor, other aids may be called in to assist the clinical diagnosis, such as the tuberculin tests, estimation of the leukocytes, and skiagraphy. Nor 494 DISEASES OF JOINTS should the surgeon forget that other aflFections besides arthritis may cause rigidity, flexion, adduction, etc. Among such may be mentioned inguinal or femoral adenitis, psoas abscess (p. 607), and even appendi- citis. Attention to the clinical history and physical signs will exclude such affections as fracture of the cervix femoris, congenital or trau- matic dislocation of the hip, coxa vara, and deformity from infantile arthritis. Treatment. — Recumbency should be insisted on in all early cases, with weight extension of two or three pounds applied in the axis of the deformity (Fig. 512). Sufficient fixation usually is secured by Fig. 513. — Thomas hip brace. Episcopal Hospital. Fig. 514. — Thomas hi]) brace; rear view. strapping the body to a Bradford frame. If this cannot be procured, a binder's-board splint or light plaster cast may be applied to the hip and pelvis, weight-extension being used in addition. In most cases, after a week or two, muscular spasm disappears and full ex- tension may be secured. The temperature should be recorded twice daily, in this as in all acute tuberculous conditions; it forms a valu- able guide as to the progress of the local lesion. After one or two months of recumbency examination may disclose an apparently nor- mal joint, and the temperature curve may be quite satisfactory; but this merely indicates that the disease is latent, not that it is cured. TUBERCULOSIS OF THK J/Il' 49.5 \\'lii'ii s\ luptums have hocn al)sent for a luoiitli or more, aiiil)ula- tory treatment may be cautiously tried. In this, joint fixation may- be jixadually relaxed, but weight-bearing should be prevented for a long time to come. \'arious braces are in use for this stage of treat- ment: with all, a high shoe is worn on the healthy side, and crutches are used, allowing the diseased limb to swing free of the ground. The brace of II. O. Thomas (1875) (Figs. 513 and 514), prox idea fixation at the hi]), and traction is secured by the weight of the limb; l)ut it is impossible for the })atient to sit down with the brace on, and the limb may rotate within the brace, giving rise to unsuspected H^:i ' 5 ^^^^H ^ ^M^ I 1 ^H/^K^^ft ^ |k.'-< i 1 jJTjHM^^M^sli^l^HHKi^ m Fig. .515.- -Taylor hip brace. Episcopal Hospital. Fig. 516. — G. G. Davis's brace for coxalgia. Orthopa?dic Hospital. deformity. About 1855 H. G. Davis introduced the method of traction in ambulatory splints; a modification of this, introduced in 1873 by C. F. Taylor (Fig. 515), consists of a pelvic band, passing around the pelvis between the anterior superior iliac spines and the level of the great trochanters, to which is attached a long outside iron extending below the foot beneath which it forms a stirrup; to the stirrup traction straps are fastened from the foot, counter-extension being provided by a perineal strap. Movements of flexion and extension are per- mitted at the hip, as the outside iron is jointed below the pelvic band; this allows a sitting posture to be assumed. A more efficient brace 496 DISEASES OF JOINTS is that of G. G. Davis (Fig. 510), in which besides a perineal strap for counter-extension, as in the Taylor brace, an inside iron is added which supports a well-padded bar passing from one side iron to the other beneath the tuber ischii; on this bar the patient sits, absolutely preventing weight-bearing on the diseased joint, while the foot exten- sion keeps the lower extremity taut, aiding the weight of the limb in securing traction. If braces cannot be secured, a spica bandage of plaster of Paris may be applied to the thigh and pelvis, preferably fixing the knee and ankle also; and with a high shoe on the sound side, and crutches, the patient may do well, though a well-fitting brace is much more cleanly and comfortable. Usually it is well for the brace to be worn night and day at first, until it is certain that no recurrence of symptoms is to be feared, when it may be left off at night. While a patient is wearing a brace, he should be seen by the surgeon every two or three weeks; and the surgeon should himself see, personally, that the brace fits comfortably and is efficient. If he is unwilling or unable to undertake the responsibilities of mechanical treatment, he should retire from the case. If it is found that under ambulatory treatment symptoms of coxitis return, recumbent treatment should be resumed, and carried out as already indicated. When, however, ambulatory treatment succeeds, joint fixation may be gradually dispensed with. If eight months or a year are passed without any symptoms whatever of joint trouble, it probably will be safe to discard the brace, but a high shoe on the sound side and the use of crutches should be insisted on for a much longer period. Then the high shoe may be abandoned, and crutches alone used, until by very gradual stages weight-bearing is proved safe. I am well aware that some orthopedic surgeons at present are opposed to such conservative measures, and prefer to follow the example of Lorenz (1906), in treating all early cases of coxalgia by weight-bearing, fixing the joint in the attitude of deformity by a gypsum splint, and abolishing recumbency and traction entirely from their plan of treatment. But the plan here recommended seems to me the most rational when the pathology of the lesions is con- sidered, and is still employed by the majority of judicious surgeons in this country. Great Britain, and France; and I am convinced that if rigorously employed from the earliest stage, it will cure a much larger proportion of patients without ankylosis than will the method of Lorenz, though the course of treatment may be longer. The treatment of cold abscess and sinuses, with secondary infection, has been so fully discussed at p. 4S4, that little need be said here. In almost all cases recumbent treatment, and heliotherapy, alone or with bismuth or iodin injections, will cause sinuses to close eventually. Very rarely it may be necessary to remove a sequestrum or some carious bone by the curette; then the cavity should be filled with iodoform bone-wax (p. 435). Almost never is formal excision necessary or desirable in children, and then only to avert death from sepsis, and rVHERCrLOSIS OF THE Ull' 497 as a less severe remedy than amputation, I liave done only two excisions of the hip, employed as a last resort in cases of profuse suppuration and prolonged liectic: one hoy (Fig. 40")) recovered with the usual shortened and detormed, tiiough useful limh (Figs. ")17and 518); the other, though temporary improvement was secured (Fig. '.V2), died two months later from tuberculous meningitis. Excision of the hi}) for tuberculosis siiould l)e regarded merely as a method of joint Fig. 517. — Ridult (jf excision of hip for tuberculosis, in a boy of fourteen years, one year after operation. (Dr. H. C. Deaver's case.) (See Fig. 518.) Epis- copal Hospital. Fig. 518. — Excision of left hip for coxalgia; age fourteen jears. Left hij) in slight adduction; apparent shortening three inches, actual shortening one and a half inches; still uses crutches; wound dry but scabby; one j^ear after operation. Episcopal Hospital. disinfection (Coudray, 1911), and should be as conservative in extent as is possible with such end in view. An anterior incision is best, as originally advocated by Hueter (1878), and later adopted by R. W. Parker; this incision is made on the outer side of the sartorius, displacing the rectus and ilio-psoas to the inner side (Barker, 1888) ; as much synovia should be removed as possible. In very septic cases the posterior longitudinal incision is preferable. This was u.sed by C. White, of Manchester (1769), and was known during the nineteenth 32 498 DISEASES OF JOINTS century by Langenbeck's name. After detaching the muscles from the great trochanter the femur is divided below this process, the entire upper end being removed; the acetabulum also is gouged away if necrotic. Though the immediate mortality of the operation is only about 5 per cent., yet when employed for the cases here described as suitable for such treatment, the ultimate death rate is from 20 to 25 per cent. If employed in less severe cases in which it is not necessary, the death rate will, of course, be less. Amputation occa- sionally may save a life after excision and re-excision have failed. After the operation recumbent treatment with fixation and traction is con- tinued until latency of symp- toms indicates the propriety of passing to ambulatory treatment. Ankylosis should be encouraged. ' Ely (1911) thinks the benefit of excision in hip disease is due to the luxation of the femur which often results, thus perma- nently abolishing the joint as such, as effectually as would ankylosis (p. 481). In adults, in whom tuber- culosis of the hip is rare, ex- cision is more often required, but, fortunately, the resulting disability is less. Tuberculosis of the Knee. — This is the most frequent form of tuberculous joint dis- ease in adults, in whom the primary lesion often is syno- vial; but the knee is often attacked in children also, and in them usually the femur, tibia, or patella is first involved. In the knee, as in the elbow, local signs of arthritis are much more marked than in the hip, consisting in heat, dusky redness, typical fusiform swelling, and occasionally in intra-articular eft'usion. Usually, how- ever, enlargement of the joint is due to fungus granulation tissue, and though it may seem as if fluctuation was present, aspiration will fail to demonstrate fluid. The patella does not float, but early becomes fixed more or less firmly to the condyles of the femur (Fig. 519). The knee is flexed, and contractures of the hamstrings develop. Fig. 519. — Skiagraph of tuberculous arthritis of knee; age thirty-seven years; duration seven years. Same patient as in Fig. 520. Episcopal Hospital. TUBERCULOSIS OF THE KNEE 499 In iulvaiurd cases iiostcrior sul)luxati()ii of tlio tibia (occurs, usually accoinpaniod also hy rotation outward. Starting pains are very annoying, and the patient lies curled uj) on the diseased side, his whole attention apparentl\- concentrated in protecting the painful joint from injur>- or motion. Cold abscess is rarer than in hip disease, and sinuses more freciuently are of extra-articular origin. Treatment. -The treatment consists in local rest, secured in acute cases by recumbency with splinting and weight-extension. In less severe cases the fixation by plaster of Paris without traction may suffice, and if the gypsum is renewed every four or five weeks gradual decrease of the de- formity may be secured. Weight - bearing usually should be allowed before motion at the knee, but for some months after am- bulatory treatment is com- menced it is safer to employ a traction brace, much the same as in hip disease, with a high shoe on the healthy foot, and crutches. If conservative treatment is persisted in for a year, and the disease fails to be- come latent, the question of operative treatment may arise : in children below the age of puberty all that should be attempted is erasion of the joint (arth- rectomy, p. 486); and though by resort to this operation the disease may not be permanently cured, and though, as is frequent, flexion deformity develops after operation, it may be possible by its aid to tide the patient over the years of childhood until formal excision can be safely done. In adults the results of conservative treatment are very disappointing (Fig. 520) ; if, after judicious trial of this for some months, no improvement occurs, or if the disease constantly lights up afresh when ambulatory treatment is adopted, excision of the knee should be done; and m Fig. 520. — Skiagraph of tuberculous arthritis of knee, showing destruction of external condyle of femur, external tuberosity of tibia and perforation of cartilage of tibia. Age thirty-seven years; duration seven j^ears. Probably synovial in origin. Treated by excision. Episcopal Hospital. 500 DISEASES OF JOINTS practically all cases in adults with sinuses or secondary infection, early excision will give the best results (Fig. 521). The ojjcration has been described at p. 469. Ankylosis should be firm in eight to ten weeks. Even if excision fails to cure the disease at once, which rarely is the case, the surgeon must not conclude that immediate amputation is necessary; by persistence in conservative measures, firm ankylosis and healing of sinuses may yet occur; or a re-excision may be more successful. Amputation should be regarded as the last resort, chiefly adapted to the very old. By excision the limb will be shortened from one-half to two inches. During convalescence from operation the tendency to development of genu \arum must be guarded against, as well as the tendency of the femur to ride for- ward on the tibia. The patient should wear an orthopedic apparatus to fix the knee for a year. The immediate mortality of the operation is about 5 to 10 per cent. Fig. 521. — Specimen from excision of left knee for tuberculosis. (See Figs. 519 [and 520.) Episcopal Hospital. Vic. 52l'. — Tul)t'rcul<)sis of left ankle-joint. Episcopal Hospital. Tuberculosis of the Ankle and Tarsus. — The diagnosis sometimes is difficult in children or adolescents, in whom painful flat-foot (p. 547) may be the primary symptom. The astragalus and calcaneum are the bones most often affected, but owing to the proximity of so much synovial membrane (Fig. 165), early joint invasion occurs (Fig. 522), and fistulization with secondary infection is very common. Treatment. — Treatment, even when the diagnosis is only tentative, should be by rest and cessation of weight-bearing, secured by a gypsum case and use of crutches. This usually is sufficient in children, in whom sinuses soon close, and erasion rarely is required. If motion is prevented by a suitable brace, weight-bearing may be resumed a few months after cessation of active symptoms. In adults, on the other hand, time should not be lost in conservative treatment unless improvement is progressive; if the disease seems stationary, and especially if the foot grows worse, erasion or excision should be resorted TUBERCULOSIS OF THE- F.LIiOW 501 to without (Ichiy. The entire astragalus should he renioNi-d, and as much of the t ulxrculous soft parts as p()ssil)le. Usually the sur},'eon Fig. o2'.i. — Tiil^erculosis of elbow in a child of four years, showing typical fusiform .swellinji; also tuberculous spon- dylitis, and tuberculous osteomyelitis of left forearm and hand with sinuses. This condition iseuphonioiisly descrilied as the "moist rot." Children's Hospital. Fig. 524. — Tuberculosis of elbow. Age seven years; duration four years; sinuses for four months. Also tuber- culous cervical adenitis. (See Fig. 525.) Orthopedic Hospital. finds that he has delayed too long, and that while this con- servative operation may improve matters for a while, amputation eventually will be necessary. Tuberculosis of the Elbow is much more frequent in children than in adults. The primary lesion is more often in the ulna or humerus than in the radius. Joint invasion is rapid, and typical fusi- form enlargement results (Fig. 523). Fistulization is difficult to prevent (Fig. 524), and cure seldom oc- curs except by ankylosis, and it is better, especially in children, to encourage ankylosis and closure of sinuses than to resort to precocious excision (Fig. 525). No effort should be made to restore motion until all symptoms have been absent for many months. Then an excision or arthroplasty may be done. Fig. 525. — Tuberculous ell)ow, fibrous anky- losis, sinuses healed. Age ten years. Three and a half years after Fig. 524. 502 DISEASES OF JOINTS Tuberculosis of the Wrist. — This is rare in children; immobilization promptly employed and long continned usnally prodnces a cure with only moderate limitation of mot on. In adults sinuses are prone to form, and amputation is the usual termination, though erasion should be tried first. Formal excision of the wrist is very rarely advisable (p. 470); firm fibrous ankylosis is songht, and the hand seldom is verv useful. Fig. 526. — Syphilitic arthritis of left elbow. Ago fourteen years: duration two years. Also interstitial keratitis and slight sabre-blade tibia. Orthopsedic Hospital. Fii,. .j_'7. — S\ jiliilitir arthritic of both knees. Age thirteen year.s; dura- tion five months. Orthopsedic Hos- pital. Tuberculosis of the Sacro-iUac Joint is very rare, especially in children. The symptoms are pain, sometimes radiating down the sciatic nerve, localized tenderness over the affected joint, and a peculiar feeling of insecurity in the pelvis on attempts to walk. When standing, the body is inclined away from the diseased side, as in " sciatica. " Examination shows no involvement of the hip or vertebrae ; hyper-flexion of the hip on the diseased side occurs to the normal extent unless the knee is kept extended, when it will be impossible to flex the hip as far on the diseased as on the healthy side, since muscular spasm will be roused by traction on the ischium through the tense hamstrings. Pressing the iliac crests together, and attempts at antero-posterior motion in the pelvic joints cause pain. In advanced cases swelling over the dorsal or pelvic surface of the joint occurs, and suppuration may develop, with sinuses posteriorly or in the inguinal or adductor regions. Treatment. — Recumbency, with weight-extension for many months, is required. No form of apparatus is satisfactory in preventing weight-bearing at the sacro-iliac joint, and recurrence of symptoms TUMORS OF JOINTS 503 is not iimisual wlieii ambulaton' treatment is att('nij)t('(l. A few recoveries have i)een reported after resection of tiie joint, but even in adults tiiis should be reserved until conservative measures have proved inelfectual. l^i((pie (1910) reports seven resections of the sacro-iliac joint for tuberculosis: two patients were cured, three were recovering- ("nearly cured"), one died of cachexia, and the last had amyloid dcireneration of the viscera and death was anticipated. Syphilis of the Joints. — Syphilitic arthritis is not very rare in cases of hereditary lues, but often, especially in the acquired form of the disease, is not reco^ijnized. In its clinical aspects the disease nuich reseml)les tuberculous arthritis, especially of the primary synovial type, but pain is less severe. The diagnosis usually is made from concomitant evidences of syphilis (Figs. o2() and 527), and is confirmed by the AVassermann reaction and results of antisy})hilitic treatment. If the joint is painful, suitable apparatus should be i)roNided. TUMORS OF JOINTS. Tumors of the joints, except those developed from the neighboring bones, are quite rare. Lipoma Arborescens is the name given by Volkmann (1882) to a synovial or subsyno\ial growth in which fatty deposits occur. It is observed oftenest in the knee, along one side of the tendo patelhe, but also occurs in the shoulder. It is regarded by Poncet, Marsh, Ely, and Whitman as tuberculous in nature, and there is no doubt that sometimes it is; but it is better to consider it, with Nichols (1907), a hypertrophic synovial change which may occur in various joint afl'ections. The fatty out-growth is more or less pedunculated, is palpable through the skin as an ill-defined mass, and interferes with the functions of the joint without producing very acute symptoms. The best treatment is excision of the growth. Sarcoma. — Primary sarcoma (endothelioma) of joints is rare. It begins in the synovia or subsynovial connecti^'e tissue. Lejars and Rubens-Duval (1910) have collected 16 cases, 13 of which occurred in the knee. This is one of those neoplasms where transition from epithelioid to sarcomatoid tissue is best observed. The clinical symptoms somewhat resemble a subacute infectious arthritis, and the diagnosis usually depends on microscopical examination of an excised specimen. If the tumor recurs after local extirpation, amputation should be done. CHAPTER X\\ . ORTHOPEDIC SURGERY. Orthopedics, from the Greek words oaf^o; and ~«^c, meaning lit- erally a straight child, is that part of surgery which deals with the correction of deformities, either congenital or acquired. So many surgeons, during the last fifty years or more, have devoted their exclu- sive attention to this subject, that the practice of orthopedic surgery is now recognized as a specialty of equal rank with gynecology or genito-urinary surgery. In the limits of a text-book on general sur- gery, therefore, it is manifestly impossible to do more than provide an outline of the subject, and inculcate the general principles which underlie its practice. CONGENITAL DEFORMITIES. Congenital Absence of Bones is not very rare. Those most often deficient are the radius, and the tibia or fibula. Sometimes the outer portion of the foot is absent along with the fibula, or a portion of the hand absent with the radius. The exact diagnosis often depends on skiagraphy. The hand or foot deviates toward the side where its support is lacking. In infancy malposition may be prevented or corrected by splints, or other apparatus. Often during childhood or adolescence it becomes necessary to operate for the correction of deformity, or to improve function. In the foot, some form of arthro- desis (p. 528) usually will be required to give stability in walking,' while in the upper extremity it may seem desirable to lengthen con- tracted muscles and tendons, and do osteotomy or resection of the existing bone for cosmetic effect, though function can seldom be improved. Osteoplastic Operations. — After resection of a large part of the diaphysis of a bone, for osteomyelitis or tumor, the limb often is left in a helpless condition, much as in the cases of congenital deformity noted above. When the shaft of the tibia has been excised, and fails to regenerate, the upper end of the fibula may be moved over later to a socket cut in the upper epiphysis of the tibia (Hahn, 1S84); in cases reported by Nichols (1904), Huntington (1905), and others, the fibula underwent hypertrophy and supported the weight of the body very well. In other cases a portion of the diaphysis of the femur, ^ Wille (1909) in a case of congenital absence of the fibula did arthrodesis by driving a fibula (obtained from an amputated leg) up from the sole, through the calcis, astragalus, and tibia, and obtained a fair result. CONGENITAL DEFORMITIES 505 IniuuTiis, or otluT long bone, lias hocn replaced immediately by traiisi)laiitiiig a jxtrtioii of tlu> patient's tibia, ent long enongli to fill the defect, and about half an inch in diameter. This "trans- plant" must be brought into contact, at least at one end, with healthy bone, containing Ibnersiaii systeins, so that the osteoblasts lining these may grow along the channels in the transplant, and thus lay down new bone in place of that contained in the transj)lant, which is slowl\' absorbed by the osteo- clasts. If the transplant is not brought into contact with a healthy Haversian system, it will not l)e j)ermeated by osteoblasts, but will be gradually ab- sorbed and the operation will be a failure (Murphy, 1912). Many sur- geons prefer to preserve the perios- teum of the transplant, thinking it favors bone growth. I have always removed the periosteum before cut- ting the transplant. Congenital Absence of Muscles (Fig. o2l'jeation of right hip. Three and a half years after reduction. Same patient as Fig. 537. Orthopsedic Hospital. structures have been stretched enough to allow the groin to come in contact with the table, the head of the femur ma>' jump from the posterior to the anterior plane of the pelvis with an audible and palpable click. If not, the flexion of the thigh is slightly diminished {i. e., it is drawn a little away from the chest) and its abduction is slightly increased, by raising the knee a short distance from the table. Pressure downward on the trochanter is continued until the head of the femur can be felt by the finger in the groin. If reduction cannot be secured at the first attempt without the use of unjustifiable force, it is better to dress the limb in the fullest abduction possible and CONGEMTA L DISIJH A TIOXS 511 make another attcnij)! sc\cral weeks later il' iieeessary, after sub- cutaneous tlivision of tlie adductor muscles, close to the pubis. When reduction has been secured, tiiis fact may be determined (1) l)y hearinj^ or fecHng the femoral head junij) into tlie acetabulum; (2) by observinjf that the knee can no lonj^er be fully extended, since the ascent of the femur from the posterior plane of the innominate Fig. 539. — Fracture of neck of femur when hyper-abduction is attempted according to Lorenz's method. bone to the acetabulum has caused a relative shortening of the ham- strings; (3) by palpating the head of the femur in its socket below Poupart's ligament; (4) b}' reproducing the luxation and again redu- cing it; and (5) by skiagraphy. Sometimes an "anterior transposition" only is secured : in this the head, instead of jumping into the acetabu- lum, passes above it to a position just below the anterior superior spine Fig. 540. — G. G. Davis's method of reducing congenital dislocation of hijj. Orthopaedic Hospital. of the ilium; of course this is not so favorable a result as an "anatomical reposition," but it is better than a persistence of the dislocation, since it transfers the weight-bearing point to the centre of gravity. After reduction the head of the femur is not at all stable in its ill- formed socket, and the chief difficulty and tedium in the care of these cases arises in the after-treatment, in efforts to prevent relapse. The limb should be dressed in plaster of Paris in the most stable 'position; 512 ORTHOPEDIC SURGERY usually this is with the thigh flexed to a right angle and abducted beyond the coronal plane; that is, so that the knee is in a plane 2^05- terior to the symphysis pubis (Fig. 541). This, the "primary position," Fig. 541. — Congenital dislocation of right hip; primary dressing. Photographed two weeks after operation. Same patient as Pigs. 537, 538, and 543. Orthopaedics Hospital. Fig. 542. — Frog position after reduction of congenital dislocation of both hips. Orthopaedic Hospital. CONGENITAL DISLOCATIONS 513 called also the "tVo^^ position" wlicn hotli liij)s arc coiKHTiicd (Fig. 542), must l)c iiiaintaiiicd tor from four to six months. During this time the child nuist be encouraged to walk about, with sup])ort, as weijiht-bearing favors the deepening of the acetabulum. At the end of this time, unless rcluxation has occurred or is inuuincnt, the abduc- tion and ilexion may be diminished gradually, and the thigh dressed in a less awkward position (Fig. 543), in which locomotion is easier. Sometimes greater stability is secured by dressing the limb with the patella looking directly forward, without any external rotation of the thigh. Innnobilization of the hij) nuist be coutiinied, except in very young children, for from nine to eighteen months after the primary reposition, and for a similar or longer period after any recurrence of dislocation and secondary reposition. After this time external su])i)ort may be discontinued, and gentle passive motion and massage may be prescribed. The younger the child, the sooner, as a rule, can external support be dis- pensed with, and the sooner will func- tion return. If reluxation recurs persistently, and in cases where bloodless reposition is impossible, a resort to open operation usually is proper. The best approach is by an anterior incision, along the inner border of the sartorius. HoflFa (ISOO) used a posterior incision with temporary resection of the great tro- chanter, but later abandoned this method. Lorenz (1892) used an in- cision from the anterior superior iliac spine to the great trochanter, passing between the tensor vaginae femoris and gluteus medius; I have used this method with satisfaction. Ludloflf (190(S) uses an internal incision, pass- ing between the adductors and pecti- neus. In all cases the capsule is widely opened, preserving the Y-ligament; and the acetabulum is cleared out sufficiently to hold the head of the femur. Structures preventing reduction should be divided; but in adults, where utmost efforts sometimes fail to secure reduction, it may be sufficient to form a new^ socket above the acetabulum (G. G. Davis, 1908). A certain measure of relief will be secured if the head of the femur becomes more firmly fixed, in any position, than it was l)efore operation. Congenital Dislocation of the Shoulder. — In many cases it is prob- able that the displacement occurs during obstetrical delivery. The dislocation nearly always is subspinous (Fig. 544); the attitude is characteristic; and the diagnosis easy. Reduction rarely is possible 33 Fig. 543. — Congonital dislocation of right hip in walkiup; cast. Same patient as Figs. 537, 538, and 541. Orthopsedic Hospital. 514 ORTHOPEDIC SURGERY Fig. 544. — Congenital dislocation of the left shoulder. Age seven years. Orthopcedic Hospital. without open operation. This dis- location not infrequently accom- panies the condition designated "brachial birth palsy," and accord- ing to T. T. Thomas, the dislocation is the essential lesion (p. 2S3). Congenital Elevation of the Scapula, Sprengel's Deformity (1891).— The upper extremity develops as an appendage of the cervical spine, and if normal descent of the scap- ula fails to occur, it remains in the cervico-dorsal region, more or less deformed, often being fixed to the \'ertebral spines by a process of bone or cartilage. The subject has been studied recently by A. E. Horwitz (1908), who analyzed 136 cases. In the patient under my own care (Fig. 545), who also presented Fig. .545. — ( 'ongcnital elevation of left scapula in a boy of three years; before operation. Orthopaedic Hospital. Fig. 54(i. — ('ongcnital elevation of left scapula, three months after opera- tion. Orthopaedic Hospital. CONGENITAL T A LIVES 515 con^M'iiital scoliosis and al)S('nce of several rihs, marked iiiij)rovenient resulted t'roin open section of the muscles attached to the xertehrai border of the scapula, depression of the scapula, and re-attachment of the rhomboids to the upper anjjle of the bone (Fig. 54()), Congenital Dislocation of the Knee is quite rare, and usually is anterior in direction, the leg being hyperextended on the thigh. The patella may be absent. The use of splints or orthopedic api)aratus usually secures a return to the normal position, with moderate range of fl(>xion, before the age for AA'alking arrives. Congenital Talipes. — The cause of congenital foot deformities is unknown, though they often are attributed to malj)osition in the uterus. The hands sometimes are the seat of similar deformities {Cluh Hands). The deformity may affect one or both feet. There are several distinct types of deformity, though usually more than one is present. Talipes Equinus is "pointed toe" deformity in w'hich the front of the foot is depressed and the heel elevated, the patient walking on the toes, as a horse, whence the name. In Talipes Calcaneus the heel is de- pressed and the toes elevated. In Talipes Varus the anterior part of the foot is adducted, and the foot is inverted (supinated); the inner border of the sole is shortened and elcA'ated, and the patient walks on the outer border. In Talipes Valgus the anterior part of the foot is abducted, the foot is everted and pronated, the sole is flat, and the inner border of the foot is convex. In Talipes Cams or Arcuatus ("hollow foot") the arch of the foot is high, and the foot is shortened antero-posteri- orly, without being either pronated or supinated. At birth there seldom is appreciable bony deformity, but contrac- tures of tendons and ligaments as well as of the skin and subcutaneous tissues are present. If the deformity is not overcome while the bones are soft, these will become deformed, adapting their form to the altered function required by weight-bearing and locomotion. Equino-varus. — The most frequent combination of congenital deformities is that of equimis and tarns, forming the ordinary "club- foot" (Fig. 54S); there often is slight cams as well. The feet turn in, the soles face each other, the tibial border of the sole is concave and shortened, and the heel is elevated. There is no natural ten- dency for the deformity to correct itself; on the contrary, if patients Fig. 547. — Congenital talipes equinus, with slight cavus deform- ity in a boy of thirteen years. Orthopaedic Hospital. 51G ORTHOPEDIC SURGERY Fig. 548. — Congenital equino -varus (double), age seven months. (See Fig. 549.) Orthopiedie Hospital. are iiefeet and contracture of knee. Age three years. Episcopal Hospital. PA RA L Y TIC DEFOIi.\ffTII'JS 521 of ()V(*r('()niiii<; tlio doformity is to do cuneiform tarsectomy, or wedj^e- sliapcd ri'soctioii ol' the tarsus (\{. I)a\\-, lSSlj:iii this operation u wod^e of l)one (regardless of tlie outlines of the individual bones), witii its base on tiie dorsum and its apex on the sole, is removed from across the tarsus; the portion excised hv'iu^ sufhciently lar' ^vhich apparatus may be discarded. showing secondary cavus, when \Yhenever there are a sufficient number toes were forcibly flexed. Same c i 1^1 1 !> j.\ -^ • patient as Fig. 565. ot healthy muscies tor the purpose, it is Fig. 567. — Paralytic calcaneus after transplantation of the peronei and tibialis posticus into the caicaneum, showing power of raising the heel. (See Figs. 565. 566, and 568.) Orthopaedic Hospital. PARMA TIC DEFORMITIES 525 possible, \)\ cliaii^iiig tlie points of insertion of one or more, so to dis- tribute the muscular power wliieh remains as to secure to the patient a well balanced foot. This o])erati(m is known as Tendon Transplanta- tion. It seldom isadvisable to employ it before the age of six years, since before this age it is very difficult to be certain which muscles are functionally active, because this is a point ascertained much more accurately by clinical observation than by investigation of the elec- trical reactions. IJefore tendon transplantation is attempted, it is important to overcome all deformity, and this may require repeated manipulation under an anesthetic, red ressement force (as in congenital talipes, p. 518), or even tenotomies; only when the foot can be held Fig. 568. — Paralytic calcaneus two months after tendon transplantation. (See Figs. 565, 566, and 567.) Orthopaedic Hospital. in the over-corrected position by the pressure of one finger, will it be safe to resort to operation. The best method of tendon trans- plantation is the periosteal insertion of Lange (1898); this may be succinctly described by a concrete example, namely, the transplan- tation of the tibialis anticus to the base of the fifth metatarsal bone, for the relief of ^'arus due to paralysis of the peroneal muscles. Under Esmarch anemia the tibialis anticus is divided at its insertion, and is drawn out of its sheath through a second incision made over its course above the annular ligament; a subcutaneous channel is then burrowed from above the annular ligament to the tuberosity of the fifth metatarsal bone, and through a third incision at the 526 ORTHOPEDIC SURGERY latter })()iiit tlie tendon of the tibialis anticus is drawn down, and under the utmost possihk- tension is sutured to the periosteum by several Fig. 569. — Paralytic valgus, age seven years; treated by tendon transplantation. (See Fig. 570.) Orthopsedie Hospital. Fig. 570. — Patient .shown in Fig. 569. After transplantation of peroneus brevis and tertius to insertion of tibialis anticus. mattress sutures of strong chromic catgut. The foot is immobilized in over-corrected position (valgus), in gypsum, for eight weeks; func- tion is then gradually resumed. ^ 1 The tibialis antictis being now ^^^^^ -^/tT >v^ inserted on the outer side of the ^^^Er " 7 J ^^"^^ ^^^^ ^*^"^ ^^ ^" everter, largely ^^^1 A fl replacing the paralyzed peronei, ^^^H I ^^A 1 and rendering the further use of ^^^H ^^^^^B I apparatus ^^^H ^H^^H I In similar manner, for other de- ^^^H ^^^^^^B I formities, ^'arious other tendons ^^^H ^^^^^^H fl may be transplanted, as will oc- ^^^H ^^^^^^H ■ to the mind of any ingenious ^^^V ^^^^^^B H surgeon. For paralytic valgus it is ^^^ ^^^^^V V best to transplant the extensor B^ ^^^^^^^^m fl longus hallucis to the insertion of ^^j^^^^^^^^^^r fl the tibialis anticus; when the exten- ^^^^^^^^^^^^m ^M longus hallucis paralyzed ^^^^^^^^^^^^■■■i^HH ferred to the insertion of the tibi- FiG. 571. — Paralytic cavus, age alis anticus (Figs. 5G9 and 570); or eleven years showing over-action of if the extenSOr longUS digitorum is the extensor longus hallucis. Ortho- .. j, t , i i p .i j.m • i- pffidic Hospital. active, the (h.sinl end ot the tibiaUs I'A UAL YTK ■ DKI'OUMrjJI'JS 527 aiiticus (\e the annular li^anicnt) may be sutured to this healthy tendon. For paralytic cavus, the extensor lon^'us lialiucis, which is usually the deforming factor (Fig. 571), may be attached to the head of the first metatarsal. For paralytic calcaneus the peronei and tibialis posticus may be traiisi)lanted into the insertion of the tcndo Achillis (Figs. 5(')r) to 5()S). For paralysis of the quadriceps femoris one or more of the hamstrings may be transplanted into the patella; and for paralysis of the internal rotators of the thigh, the tensor fascijie femoris may be transplanted into the great trochanter (G. G. Davis. 1011). Fic 572. — Paralj-tic flail-foot, age eighteen j-ears; duration fourteen years. (See Fig. 573.) Orthopaedic Hospital. In many cases it is possible by shortening paralyzed tendons to enable them to act as ligaments in maintaining better position, or when slight power remains, to enable them to use it to better advan- tage. If a healthy tendon is too short to be available for purposes of transplantation, silk strands may be attached to its end in an imbri- cated manner, and the tendon thus lengthened the required amount. Nerve Anastomosis has been employed in some cases of paralytic deformities of the feet, but not with much success. It should be reserved for those cases in which the entire distribution of one nerve is })aralyzed, but in which the entire flistril)ution of a neighboring nerve is intact. I employed it in one case in which the entire distri- bution of the anterior tibial nerve was paralyzed, but in which that of the musculo-cutaneous was unaffected, anastomosing the peripheral 528 ORTHOPEDIC SURGERY end of the anterior tibial into the musculo-cutaneous; but no power was re«;aine(l. Arthrodesis. — When so many muscles are paralyzed that none are available for transplantation, it is possible to convert a "dangle-foot" with flail-joints (Fig. 572) into a firm and useful support by pro- ducing an artificial ankylosis (Fig. 573). This operation, known as arthrodesis (Fig. 574), should not be undertaken before the age of nine years at least, since the bones of younger patients are still too cartilaginous for firm union to follow a joint resection. For "foot- drop," arthrodesis of the ankle-joint is done: through a small trans- verse incision over the front of the joint, displacing the tendons, the articulating surfaces of the astragalus, tibia, and fibula are removed.^ Fig. 573. — Result of arthrodesis of ankle, and subastragalar joints for paralytic flail-foot (Fig. 572). (See Fig. 574.) Orthopedic Hospital. For lateral mobility, subastragalar arthrodesis is done; in eight cases I have found a single external incision, above the peroneal tendons, sufficient to remove the articulating surfaces of astragalus and calca- neum, as well as those of astragalus and scaphoid (Fig. 165). The wounds are closed without drainage, and the foot is fixed in gypsum for eight weeks, when walking may be resumed; but a light brace should be worn for a few months more. 1 To secure closer apposition, Goldthwait (1908) advises osteotomy of the fibula just above the malleolus, with inward displacement of this process against the astragalus. I'ARALvric 1)1<:f()I{Mitu<:s .)2<) In somr cases hoforr the ])atioiit is old ciioukIi to have arthrodesis (hme, a Ihiil-joint may he rcMidered more or less firm l)y the insertion thron^h the hones of sIvdikj .sill: .siituirs, to act - by lying prone, or supine with the lumbar spine supported by a pillow. One sacro-iliac 536 ORTHOPEDIC SURGERY joint frequently is more relaxed than the other. By placing one hand over the joint while the other palpates the symphysis pul^is, it usually is possible to detect abnormal mobility as the patient stands first on one foot then on the other. Or with the patient lying prone, the sacro-iliac joints may be made to move by hyperextending the thighs. Treatment. — The treatment in mild cases consists in massage of the lumbar muscles, with gymnastic exercises. In severe cases it may be necessary to put the patient to bed with weight extension to the lower extremities; later some form of spinal and pelvic support must be provided. For sacro-iliac relaxation the application of a firm Fiu. 582. — iSacio-iliae sprain, with re- laxation (left side). For eight months pain in left hip, back, and down sciatic. Diagnosed Pott's disease, elsewhere. Or- thopsedic Hospital. Fig. 583. — Belt for sacro-iliac relaxation. Orthoptedic Hospital. pelvic belt between trochanters and iliac crests often is all that is required (Fig. 583). Where the lumbar spine also is involved, it will be necessary to support this also: this may be accomplished by the application of a light gypsum jacket, with the patient lying prone on a hammock, as in Pott's disease (p. 611), or by some form of ortho- pedic corset which will maintain hyperextension of the lumbar spine. Spondylolisthesis is the term given to subluxation of the last lumbar vertebra forward on the sacrum; occasionally the fourth lumbar vertebra is displaced forward on the fifth. The affection is com- monest in young adult females, but occurs also in growing girls and in youths and young men. There is a depression above the sacrum, DEFORMITIES OF THE HEAD AND KECK bXi over the hist hinihar vertebra, and sometimes a promhienee ean be felt above tlie sacral eminence by a finger in the rectum or vagina. The symptoms and treatment are nuich the same as for static strains of the lumbar spine, of which, indeed, spondylolisthesis may be considered the terminal stage. DEFORMITIES OF THE HEAD AND NECK Torticollis, Caput Obstipum, or Wry-neck, sometimes is (lue to injury at birth, rupturing some of the fibres of the sternomastoid or other cervical muscle. It is uncertain whether the cases of hematoma of the ster)w-mastoid muscle sometimes seen in infants are a result of the rupture of the nuiscle because it was congenitally short, or are themselves the cause of wry-neck by causing subsequent cicatricial contraction of the muscle. Often the deformity is not noticed until the child, is several months old, and then it is difficult to be certain whether the affection is congenital or acquired. As a rule, the congenital affection is painless, while the accjuired form has a more or less acute onset. Torticollis may be symptomatic of certain other diseases, as astigmatism, or cervical Pott's disease (p. 603), fracture-dislo- cation of the cervical, spine, cer- vical rib, cervical adenitis (Fig. 584), "rheumatic stiff neck," toothache, ear-ache, tonsillitis, or other affection which may irritate the spinal accessory or upper cervical nerves, causing spasticity of the muscles concerned in the production of the deform- ity. These are especially the sternomastoid, the trapezius, and the scalenus anticus, especially the sterno-mastoid. Symptoms. — The head is rotated to the opposite side, the chin point- ing to the unaffected shoulder, while the ear approaches the shoulder of the affected side (Fig. 585). If the deformity continues long uncor- rected, it may lead to facial asymmetry, scoliosis, or other secondary deformities which cannot be remedied. Treatment. — The surgeon should first ascertain that the deformity is not of the symptomatic variety; if it is, removal or proper treat- ment of the cause of irritation usually will cause the wry-neck to disappear. If no cause other than a shortening of the muscles can be found, attempts may be made by massage, gymnastics, or apparatus to overcome the deformitv. If these fail, as in most cases they do, Fig. 584. — Torticollis from cervical adenitis. Children's Hospital. 538 ORTHOPEDIC SURGERY I'k;. ')bo. — ( 'Diiiit'iiital tui'tK quired scoliosis. Note asymmetry Children's Hospital. with ae- of face. the surgeon may resort to division of the contracted structures. In cases of short duration this usually is quite efficient, })ut in many pntients the most that can be expected is a lessening of de- formity. It is better to divide all resisting structures by open section than to attem})t a sub- cutaneous operation ; very dense cicatricial bands, which may exist in the cervical fascia, should be excised, and the muscles may be divided trans\ersely and left unsu- tured, or some form of muscle lengthening, analogous to the lengthening of ten- dons may be employed. The head is then dressed in an over-corrected position, main- tained by a gypsum case . (Fig. 58()), or orthopedic ap- paratus. Spasmodic Torticollis, a form of Tic Convulsij, is an affection of obscure origin, consisting essentially in sudden tonic involuntary, and usually painful contraction of the neck muscles, momentarily turning the head into a wry- neck position. The extent of the spasm, and the number of muscles involved, varies greatly. The disease usually begins insidiously, in young adult life, but progresses with- out intermission until almost the entire body may be in- volved; any effort to move or speak, and especially any ex- citement, brings on a spasm, and the patient may curl up in a knot, as it were, on the side affected, being abso- lutely helpless and unable to straighten himself out. ]Many surgical measures have been tried, but none have had permanent good effect; but as the same can be said for medical measures, the temporary relief which follows operation should not be despised. Division of the nerves supplying the cervical muscles Fig. 586. — Gypsum dressing after operation for left-sided congenital torticollis. Age nine- teen years. Orthopjedic Hospital. DEFORM! TIES OF THE HEM) AND NECK 530 most nflVcti'd is tlu' oix^ratioii usually (lone, ('s[)('oelich, 1909); but while good results have followed this method it is better in every case to make sure that the nerves are freed from adhesions. Spontaneous Subluxation of the Wrist or Manus Valga (Made- lung's Disease, 1878). — The symptoms of this affection usually are manifested about the age of puberty; it affects particularly females; involves both wrists in about 50 per cent, of cases; is characterized by dorsal projection of the lower ends of the ulnse, by slight radial deviation of the hand, and in its more advanced stages by subluxa- tion of the wrist forward at the radiocarpal joint (Fig. 590). Espe- cially characteristic in radiograms is the widening of the interosseous space, due to incur^'ation of the lower end of the radius, the normal flexor concavity of which becomes much exaggerated. The hand thus is carried forward with the articular surface of the radius, while the ulna, which is not displaced forward, appears to be unduly prominent. Siegrist (1908) collected 62 cases, only 10 of which were in males. Fig. 590. — Madeluiig'.s disease; male, aged twenty-four years. Began about eight years of age. Episcopal Hospital. The aft'ection has been attributed by some to adolescent rachitis; others are s'atisfied to describe it as an obscure form of osteitis affecting the radius. In the Tast few years there has been a tendency to regard it as a congenital deformity, to which attention is first directed at an age when local over-exertion and constitutional malnutrition exert their influence. In addition to the deformity there often is discom- fort from pain or ache, and some disability from loss of extension and circumduction at the wrist. Usually these are relieved In' si)linting, or orthopedic apparatus, with constitutional treatment. In severe cases osteotomy of the radius may be done to overcome deformity. Contraction of the Palmar Fascia (Dupuytren's Contraction, 1832). — This afl'ection occurs in adults past middle life, jjarticularly men, and in some cases seems to be caused by slight recurring trauma from the handles of tools, canes, etc. The patients often are gouty. In about half the cases both hands are aft'ected, usually the right before ACQl'llil-^T) nKFOlUUTIE^ OF THE LOWER EXTREMITY :yV.\ tlie left. TIio fascia is the seat of clironic infiaminatory cluui^es,' with seeoudary contraction; it l)ec()mes densely adherent to the skin; and the resnltinj:; deformity may totally disable the patient. The tlmnil) and index fin|,a'r are the last to succnmh. Fig. 591. — Dupuytrcn's contracture of the palmar fascia; earlj- stage. Age • sixty-six years. Episcopal Hospital. Temporary relief may be secured by tenotomy of the tense fascial bands, introducing the tenotome between the skin and fascia and cut- ting downward (Adams, 1879) ; the fingers should be dressed on a splint in full extension for three weeks, and this splint should be worn at night for three weeks longer. But recurrence of the deformity is usual. Excision of the contracted bands was introduced by Kocher (1SS7), and Keen (1906) reflected a skin flap, including the adherent fascia, which was then dissected off the skin before this was replaced. The fascia is so densely adherent that some sloughing is liable to occur. Lexer and others have excised skin and fascia in one piece, and filled the gap by a flap of skin transplanted from elsewhere. Trigger Finger. — Trigger finger is a condition in which there is some obstacle to vohmtary flexion or extension of the finger, which flies "shut" or "open" when passively moved past the position where it catches. The usual obstacle is a fusiform thickening of one of the flexor tendons, and the hitch occurs where the deep tendon perforates the superficial. If rest on a splint for some weeks, followed by massage, proves inefTectual in relieving the condition, the tendon sheath may be opened and the thickening of the tendon excised. Cotton (1911) refers to 160 cases, in about 40 of which operation was done. ACQUIRED DEFORMITIES OF THE LOWER EXTREMITY. Coxa Vara. — Normally the neck of the femur forms an angle of about 135 degrees with the shaft; when this angle is notably decreased 1 These are classed by the Lyons surgeons as a form of inflammatory tubercu- losis. 544 onrnoPEDic surgery (115 degrees or less) coxa vara is said to exist. The deformity con- sists in elevation of the great trochanter and a relative depression of the femoral head, which, however, retains its position within the Fig. 51)2. — Coxa vara, the result of injury during infauc.w Episcopal Hospital. re SIX years. Fig. 593.— Skiagraph of double coxa vara (rachitic). Note rachitic pelvis- acetabula pressed together. Orthopi3edic Hospital. ACQUlUEl) DEI'OHMITIES OF THE LOW Eli EXTREMITY 54o uectabiilimi. (^oxa \ aru may result from trauma, especially ej)i[)liyseal separation of tiie head or fracture of the (;ervix in children (Fig. ;')92); from rachitic softening of tlie bones, when the deformity usually is bilateral (Fig. r)9.S) ; or from no well very defined causes, chiefly in a(h)Iescents. (See Rottenstein and Ilou/.el," 1<)I(); Calve, lOlO.) Symptoms. Tiie symi)tonis are those of the underlying or preceding condition; slight limp, limitation of abduction, because the trochanter strikes the pelvis; marked prominence of the trochanter when the thigh is flexed (Fig. 594); increased range of adduction, especially when the thigh is flexed; elevation of the trochanter above Nelaton's 595. — Whitman's vvcclfio-shiiped oste- otoniv i)f tlic femur for coxa vara. Fig. 594. — Coxa vara from fracture of cervix fenioris as infant. Note prominence of great trochanter when thigh is flexed. Episcopal Hospital. Fit;. 596. — Whitman's operation for coxa vara. Consolidation has occurred in the abducted position. line; and, in cases due to trauma, usually external rotation of the lower extremity. There is moderate shortening, but seldom much pain, relief being sought for the limp and deformity. Treatment. — In many cases no treatment is required; in some, the addition of a lift to the heel brings relief by overcoming shortening. In cases with great deformity a cuneiform osteotomy of the femur may be done, as advised by Whitman (1901), removing a w^edge with its apex at the lesser trochanter; or simple linear osteotomy may suffice. The thigh is dressed in extreme abduction, and when consolidation is complete, adduction will restore approximately the normal relations of neck and shaft (Figs. 595 and 590). In recent cases of impacted fracture of the head or neck in children or adolescents, 35 546 ORTHOPEDIC SURGERY the deformity may be overeome by forcible abduction under an anesthetic. Coxa Valga (Fig. 597) is a much rarer conditi(jn, in which the neck of the femur makes with the shaft an angle of more than 135 degrees. The trochanter is less i)rominent than normally, abduction is increased and adduction diminished. There usually is outward rotation of the lower extremity. The deformity may be congenital and usually is observed in limbs which never have borne any weight. P^fforts may be made to increase the adduction by manipulation under an anesthetic. Fig. 597. — Coxa valga, apparently congenital, in a girl of twelv'e years. Angle between neck and shaft is 165 degrees on the right; on the left (normal) it is 130 degrees. Episcopal Hospital. Snapping Hip (die schnellende Hiifteja Ilanchea Ressort). This affec- tion has been the subject recently of an elaborate study by L. Heully (1911), who has collected 57 cases. He proposes the term " ressaut fascio-ghiteal ," as explaining what he believes to be the pathology of the condition which has been recognized since 1859, though dispute as to its nature has always existed. Perrin, who reported the first case, believed it to be a form of voluntary luxat on of the hip; but the study of Heully confirms the opinion of Morel-Lavallee, ACQUIRED DEI'VRMITIKS OF THE LOWER EXTREMITY 547 Clmssaijjiiao, and others, that it is duo to sudden slippinj^ of the fascia hita (altered by injury or ('on-mptoms, over two months. Also has incipient hypertrophic arthritis of hip. Orthopaedic Hospital. Treatment. — The treatment consists in care of the underlying condition (sprain, flat-foot, gonorrhea, etc.); local rest by proper orthopedic shoes, etc.; and, in cases which resist conservative measures, in excision of the exostoses. niAPTKR XVII. SnUiKKV OF THE IIKAD. SURGICAL AFFECTIONS OF THE SCALP. Birth Injuries. — Durinij; parturition that portion of the scalp whic'li protrudes into the birth canal may become edematous from pressure on surrounding parts; this condition, which is known as caput smrcdaneum, may be recognized by the history of prolonged or difficult lal)or, by tlie facts that it is present at birth, that the att'ectetl area pits on pressure and presents no signs of inflammation; while it may be distinguished from cephalhematoma (see below) by the fact that the swelling is not limited to the outline of one bone. The swelling disappears in a few hours or days, and usually no treat- ment is necessary. Cephalhe- matoma is an extravasation of blood beneath the pericra- nium; it is encountered in about one labor out of two hundred. Usually the right parietal is the bone affected, and it is probable that in many cases the bone itself is directly injured, either bent or broken (p. 564). As the pericranium is attached at the sutures, the hemorrhage never passes the limits of the bone affected; generally the condition is not noticed for a day or two after birth, and at this time the blood at the periphery may have become clotted or organized, so that the scalp presents an indurated ring with a softened or fluctuating centre. Occasionally thin plates of sub- periosteal bone develop, and the bone crackles on palpation. In most cases no treatment is required, but if no evidence of absorption is seen after two weeks the fluid may be evacuated by puncture; pressure should then be applied to prevent re-accumulation. Should infection of the hematoma occur, from the deep skin cocci or through the blood stream, it should be drained (Fig. 603). Contusions. — Contusions of the scalp are frequent at all ages. If the head is examined immediately after the injury the impress of the vulnerating body may be detected; but swelling occurs very quickly, Fig. 603. — -Suppurating cephalhematonia in an infant of five weeks. Incised. Death in four days. Children's Hospital. 552 SURGERY OF THE HEAD and usually the only signs are those of edema, and possibly hematoma. The blood usually is extravasated in the subcutaneous tissues, super- ficial to the aponeurosis of the occipito-frontalis. It may be difficult to distinguish such cases, after the lapse of a few hours, from depressed fractures of the skull as the contusion presents a soft depressed centre, surrounded by an indurated area due to inflammatory reaction and commencing organization; but firm pressure in the centre detects solid bone at the same level as the surrounding cranial surfaces, and there is no irregular outline to the depressed area, such as is commonly present in fracture; moreover, the elevated margin moves \\ith the scalp upon the bone beneath. In cases of doubt the scalp should be incised and the skull inspected. A hematoma beneath the occipito-frontalis is widely diffused, and may be of great size. In most cases hematomas of the scalp subside under pressure by bandages, application of cold, and rest in bed; if no diminution in size is evident after ten days, or if infection occurs, the hematoma should be incised, and pressure applied, when the cavity will heal by granulation. Wounds. — Wounds of the scalp may result from blunt force, as well as from cutting instruments, as the scalp is very readily split on the underlying bone. Bleeding is free, as the bloodvessels are unable to contract and retract, being enmeshed in the firm fibrous processes which bind the skin to the aponeurosis. This also renders it difficult to catch the bleeding points in hemostats, or to apply ligatures; and the surgeon often must de- pend on sutures to arrest the bleeding. Temporary control of hemorrhage is easily secured by pressure on the margins of the wound ; and during an oper- ation hemostasis sometimes may be secured by applying an Esmarch band or other form of elastic tourniquet around the crown of the head. Wounds w^hich divide the occipito-frontalis aponeurosis trans- versely gape much more than longitudinal wounds; and when the loose subaponeurotic areolar tissue is opened there is much greater danger of infection arising, especially if the wound is closed without drainage (Fig. 604). Owing to the great vascularity of the parts large portions of the scalp may be avulsed and yet retain their vitality when properly cleansed and sutured in place. When the skull has been denuded of its pericranium over large areas, some caries is ver}' apt to occur, but if the soft parts are promptly replaced no such result need be anticipated unless infection is present. Fig. 604. — Lacerated wound of the scalp, with subaponeurotic cellulitis; the result of sealing the wound with a cotton and collodion dressing. Forty-eight hours after injury the cellular infiltrate had gravitated into the temporal region where it was arrested by the attachment of the temporal fascia to the zj-- goma. Episcopal Hospital. SURGICAL AFFECTIONS OF THE SKULL 553 In all scalp wounds a lar«;(* surroundiiijj; area should he shaved, all t'()rei>,ni hodies reuio\ed from the wound, and this should he cleaned with antiseptics. Silkworm ^\\t sutures should he used, and if there is any risk of a hematoma forming, or if the subapon- eurotic sj)ace has been opened, the wound sliould be ilrained for a few days. Tumors. — Tumors of the scalp apart from sebaceous cysts{ Fig. 223, p. 2()5) are not very frequent. In infancy dermoid ci/sts (Fig. 22(), p. 2()()) sometimes are seen; these usually grow in the region of the embryonal clefts, occurring in or near the orbit, at the glabella, or over one of the fontanelles; usually they are more or less immobile, deep-seated, and are not attached to the epiderm, being thus easily distinguished from ordinary wens. If not removed in infancy, the underlying bone may be absorbed from pressure, and the growth may become adherent to the dura mater, making its removal more difficult. Papillomatous growths of the scalp should be eradicated by cauterization, or excised, as they are prone to undergo epitheliomatous change. Epithelioma often develops in scars from burns, syphilitic ulcers, etc. Sarcoma may arise in the scalp or the cranial bones, and the latter are rapidly invaded by tumors which at first were superficial (Fig. fiOo) . Usually no operation is of any use. ¥ir.. tjUo. — Sarcoma of scalp. Death a few months after photograph was made. (Dr. W. L. Rodman's case.) Pres- byterian Hospital. SURGICAL AFFECTIONS OF THE SKULL Congenital Malformations. — Cephalocele. — Occasionally at or soon after birth a fluctuating tumor of the head is found wdiich evidently protrudes through the skull and is composed of cranial contents. The growth occurs oftenest in the region of the posterior fontanelle (occipital cephalocele), though it ma}' also protrude at the root of the nose (sincipital cephalocele), or very rarely at the anterior fontanelle or through one of the cranial sutures. The tumor usually is wholly or partly reducible by pressure, which if excessive may cause symptoms of cerebral compression (p. 573) ; and it becomes more prominent and tense when the child cries. It frequently is possible to detect the defect in the cranium through which the protrusion occurs. If the protrusion is composed solely of the meninges, with subarachnoid fluid, it is called a meningocele; an encephalocele contains also some brain substance; while a protrusion formed by a diver- ticulum of one of the ventricles is called a hydrencephalocele or an encephalocystocele. It formerly was believed that the most frequent form was the meningocele; but, though the protrusion resembles this macroscopically, histological study has proved that most cases 554 SURGERY OF THE HEAD really are encephalocystoceles, as the cavity of the cyst is lined by ependymal cells, which are directly continuous with those of the ventricles of the brain, while the cyst walls are formed by an attenuated layer of cerebral tissue. The diagnosis usually is not difficult, though deep lying dermoids, in contact with the dura mater, and having its motions transmitted to them, sometimes are mistaken for cephaloceles. The prognosis is poor, most infants either dying soon after birth, or presenting in later life evidences of cerebral defects (porencei)hal()n, liydrocephalus, idiocy, etc.). Spina bifida often coexists. Treatment. — Protection should be afforded the tumor, to prevent excoriation and infection. In most cases little else can be done; but if there is only a small channel of communication with the cranial cavity, and if the child's mentality appears normal, removal of the tumor may be attempted, with closure of the skull defect by trans- planting a bone flap from a neighboring portion of the skull. Microcephalus. — When the skull is abnormally small, the child often is idiotic or feeble-minded. Keen (1890), Lannelongue (1891) and others have done linear craniotomy for this condition, on the theory that premature ossification of the cranial sutures caused compression of the brain, and that division of the cranium in a line parallel with the sagittal suture would allow the brain to expand. But the modern belief is that the smallness of the skull is the result of lack of cerebral development, and is not the cause of it. Agnew said the operation was no more use than cutting a piece out of a turtle's shell, to make him grow larger; and this is the general belief of surgeons of today. There is no surgical treatment for idiocy. Hydrocephalus. — This is a symptom of some disease of the brain or its mem})ranes, interfering with the normal circulation of the cerebrospinal fluid, and causing it to collect in abnormal amounts on the surface of the brain or within its ventricles. Hydrocephalus thus is classified as external and internal; and it may be acute or clironic, congenital or acquired. External Hydrocephalus, in which the fluid collects in the sub- arachnoid space, is very rare; many cases designated by this name really are properly classed as other conditions. There may be acute edema of the subarachnoid tissues, as the result of trauma; the "acute serous meningitis" of Quincke (1893) belongs here, as also does "hydrops ex vacuo," in which fluid collects and fills the space left by skrmkage of the brain from injury or disease. Internal Hydrocephahis. — This is met with in two distinct forms, the congenital and the acquired. Acquired Hydrocephalus usually results from obstruction or actual occlusion of the foramina at the base of the brain, by which the cerebrospinal fluid leaves the ventricles; and the most frequent cause is a basal meningitis, generally tuberculous (p. 579). Each lateral ventricle communicates with the third ventricle tlirough a foramen of IMonro; while in the roof of the fourth ventricle (which // } ■ DROCEPHA L US 555 (IniiiLs the third ventricle through the aqueduct of Sylvius) are found the foramina of Key and Retzuis, and that of IVIagendie, which are the channels of coinnuniication between the ventricular ca\ities and the suharachnold space of the brain, this being contiinious with the subarachnoid space of the chord. Occlusion of one foramen of Monro may cause unilateral hydrocephalus. Though most cases of acquired internal hydrocephalus are due to basal meningitis, yet ejMMidynial inflammations, or pressure of a brain tumor causing obstruction of the \eins of (ialen sometimes are resj)onsil)le for the condition by })roducing edema from venous stasis. The syinptoms of the acquired form of internal hydrocephalus are those of the causa- tive condition complicated by cerebral compression (p. 573); and the treatment consists in relieving the compression, as removal of the cause of the obstruction usually is out of the question. Lumbar puncture (p. 157) is useless, as the occlusion of the basal foramina prevents evacuation of the ventricles by this route; and such treat- ment may prove quickly fatal by withdrawing the support of the cerebrospinal fluid from beneath the medulla, and allowing the sui)er- incumbent pressure to crowd this down into the foramen magnum (p. 574). But as a palliative measure repeated tapping of the lateral ventricles may be done (v. Bergmann, 1888) through a trephine opening at Keen's point (1888): this is 3 cm. be- hind and an equal distance above the external auditory meatus; the needle is entered through the posterior part of the first temporal convolution, and is ' .— - directed toward the summit of Fig. 606.— Shaded portion on surface of ,1 •, • ,1 , • 1 the brain indicating the position of the the opposite pmna; the ventricle lateral ventricle within. (Campbell.) should be reached at a depth of about 4 cm. Kocher's point (1894), is 2.5 cm. to 3 cm. from the median line and 3 cm. anterior to the precentral fissure (see Cranio-cerebral Topography, p. 567) ; the needle is directed downward and backward and enters the ventricle at a depth of 4 or 5 cm. Fig. 606 illustrates the relative position of the lateral ventricles to the surface of the brain. Or a large area of bone may be removed from the cranium, relieving the ventricular pressure by allowing hernia cerebri as in the operation of decompression for brain tumor (p. 589). Congenital Hydrocephalus. — In these cases there is no obstruction or obliteration of the foramina at the base of the brain, but for some reason the cerebrospinal fluid collects in excessive quantities, and as this condition supervenes in fetal existence, or soon after birth before the cranium is ossified, there are no symptoms of cerebral compression, but progressive enlargement of the cranium occurs, and the typical hydrocephalic head is produced (Fig. 607). A fair 556 SURGERY OF THE HEAD degree of intelligence may be preserved, but in cases of extreme deformity the size and weight of the head may render the child help- less, and in most cases death from malnutrition occurs within the first two years of life. Spina bifida sometimes complicates the case, and paralyses of the limbs are not uncommon. Rarely is the disease arrested spontaneously. Fig. 607. — Congenital inteinal hydrocephalus of moderate grade. Age seventeen months. Episcopal Hospital. Treatment. — Keen (1891) and Sutherland and Cheyne (1898) attempted to drain the ventricles into the subarachnoid space (intra- cranial drainage), whence they thought the fluid could readily be absorbed by the veins which discharge into the longitudinal sinus. Cheyne used strands of catgut for this purpose, and others have used various materials, including gold and silver tubes. N. Senn (1903) drained into the siihcuianeous tissues. But the immediate mortality was unduly high, and no permanent benefit was secured in those patients who recovered, so that the operation has been abandoned. Gushing (1908), having due regard for the fact that in these congenital cases there rarely is any obstruction to the circula- tion of the cerebrospinal fluid at the base of the brain, inferred thence that the obstruction must be where the cerebrospinal fluid enters the blood vascular system {i. e., in the region of the longitudinal sinus) ; on this account he held it to be useless to attempt to establish an outflow by Keen's and Cheyne's method; but he proposed, after ascertaining that the ventricles could be drained by puncture of the lumbar spine, to divert the fluid thence into the retro-peritoneal tissues by means of a silver tube passed through the body of one of the lumbar vertebrae. He has done this operation twelve times "with a considerable measure of success." Heile (1910), in an infant of two days old, successfully employed Handley's operation (p. 270), con- necting the sac of a spina bifida with the peritoneal cavity by means of subcutaneous silk threads; a complicating hydrocephalus also disappeared. On the theory that the excess of cerebrospinal fluid INJURIES OF THE SKULL bbl is not due to (laiuiiiiiij,' up hut to liyiuTsecretion, Stiles (1905) has practised ligation of both common carotid arteries, at an interval of three weeks, and feels encouraged hy the results. INJURIES OF THE SKULL. Wounds. — Occasionally one sees incised wounds of the cranial bones, without fracture; sabre wounds sometimes occur in war, and in civil life a pen-knife or other sharp instrument may be stuck into the skull. Such injuries require no special treatment beyond removal of the foreign body, if still present, and antiseptic care of the wound. If the implement is so firmly embedded in the skull that it cannot be withdrawn, as was the case with a pen-knife wound of the skull which I treated when interne at the P'piscopal Hospital (the point of the blade having broken off), and if it is certain that the cranial cavity has not been penetrated, it will be safe to wait a few hours until reactive processes in the surrounding bone have begun, when the implement may be extracted easily. Otherwise the surround- ing bone must be removed with gouge, and the object extracted. Fractures. — For practical purposes the skull may be considered a sphere, possessed of a considerable degree of elasticity. For it to be fractured, a good deal of force is necessary, and this acts in two main ways: (1) the skull may be compressed between two diametric- ally opposite forces, or (2) it may be struck a violent blow. In the latter case the effect is the same whether the head is struck, or whether it strikes against another object; the only counter-pressure in the former case is that offered by the inertia of the head and the resist- ance of its attachments to the trunk, while in the latter there is also the momentum of what Archibald happily terms the "after-coming head." Between the diffused crush and the localized blow, there may be all grades of violence, varying from the puncture made by a pick-axe, or the blow from a black-jack, to a knockout by a sand-bag, or a crush between two heavy beams. When the cranium is compressed in one diameter it naturally expands in the diameter at right angles to the first (Saucerotte, 1769); Victor Bruns (1854) and Angus McLean (1912) measured this compensatory expansion experimentally, finding that it amounted to several millimeters. The first and most obvious result of this compression was illustrated by Ali Krogius (1907) by cracking a hazelnut by lateral compression (Fig. 608): fissures are produced which represent meridians of longitude in relation to the points of compression w^hich are regarded as poles; these fissures gape widest in the equatorial region, and when compression is relaxed they may close again completely. In the skull such fissures are very frequently seen as the result of diffused violence, and in them may be caught, as in a vise, hairs from the scalp, portions of felt from a hat, and strangest of all, foreign bodies may even pass through the fissure while it momentarily gapes, and thus be entirely hidden from view inside 558 SURGERY OF THE HEAD the cranium when the closed fissure is examined by the surgeon. These are called hiirsiing fractures (von Wahl, 1883). Another result of the compensatory expansion of the skull in the diameter at right angles to that in which it is compressed, is that at the poles there occurs an inbending of the skull (Figs. 609 and 610); that such should be the case at the point of impact of localized vio- lence, is not difficult to understand, but that a fracture from inbend- ing may occur at a point more or less remote would be luithinkable unless the elasticity of the skull and ordinary physical laws were kept in mind. This is the fracture by counter-stroke (contrecoitp) , which formerly was explained solely on the basis of vibrations which were set up by the blow, and spreading in all directions from the Fig. 60.S. — Mer-hanism of fracture of the skull by lateral compression: a meridional bursting fracture. Fig. 609. — Diagram to illustrate the elas- ticity of the skull. When the skull is com- pressed between a and b, these points ap- proach each other while the points c and d become more widely separated. (See Fig. 609.) Fig. 610. — Mechanism of fracture of the skull by counter-stroke: when the skull is compressed at a, a and b approach each other, and a fracture by inbending maj' occur at b as well as at a; or fracture by outbending may occur at c or at d. point of impact met finally at the polar point and there disrupted the skull. Though the bursting theory, originated by Chopart and other French surgeons in the eighteenth century, and re-introduced and elaborated by Felizet in France (1873), by Messerer and von Wahl in Germany, and by Dulles in America, in the eighth decade of the last century, has largely superseded the vibratory theory as an explanation of fissured fractures and fractures by counter-stroke, there can be no doubt, as pointed out by Xancrede (1884), that vibrations do occur, and are most violent where the bone is thickest, that is, at the base of the skull, where most of the fractures by counter-stroke occur. When localized violence is applied to the skull the force of the blow expends itself mostly by depressing the bone at the point struck; INJURIES OF THE .SKILL r)5<) this is the inhnuliiig frnriiire referred to above. Now, this j)oiiit l)eiii<; rej^'iirded as a pok', there are j)r<)(hiced in the surrouiidiiijf inert l)iit ehistic skull, eoneeiitric areas of eompression, or outbrnditu/.s, which rei)rescnt parallels of latitude; and at the points where the inhending and outhending* areas meet, a circular fissure or ring frdcfurr may result (Fig. (111). Occasionally a long fissure oc- curs at the ('(juatorial region when the skull is flifi'usely crushed, and, according to Archihald, this must he ex- plained as a fracture by out- bending, as must certain fis- sures which run at right angles to the meridional bursting fis- sures (Fig. ()12). In addition to the usual clas- sification of fractures, as simple, compound, depressed, etc., there are important clinical dis- tinctions between fractures of the vault of the skull and those of its ba.se. Fractures of the Vault of the Skull. — ]\Iost fractures of the vault are due to direct violence, the parietal and temporal bones being most often injured. Almost always the injury acts from outside the ^»^ Fig. 611. — Ring fracture of skull. From a specimen in the Mutter Museum of the College of Physicians of Philadelphia. Fig. 612. — Burstinj; fracture of skull from diffused violence on vertex: fissure radiating to base and widest at equator (temporal region) ; with outbending fracture (just below- parietal eminence) at right angles to main fissure. From a specimen in the Mutter Museum. skull, SO that the inner table is in the line of extension (Fig. 613), and, therefore, is more widelv fractured than the external table ^ The Flachbiegung unci Krumbiegung of Treub (1884). 560 SURGERY OF THE HEAD ;,a^^^^l ^^fe**:-. t^^^e^^^^^c^,;^;^'^^.?^*^ Fig. 613. — Teevan's diagram to show that the inner table often is more exten- sively damaged than the external, because it is in the line of extension. (Teevan, 1864). Indeed, so elastic is the skullthat a fracture of the vitreous table may occur without any fracture of the outer table. In the rare cases, mostly suicidal pistol shots, in which the cranial vault is fractured from violence within the skull, the outer table is more widely fractured than the inner. It is very unusual for the external table to be fractured without injury of the internal; it is then depressed into the diploe. In 1909 I trephined for such an injury, in a boy, aged thirteen years, at the Episcopal Hospital, Philadelphia. The amount of splintering is in in- verse ratio to the momentum of the body fracturing the skull; but in the case of gunshot wounds, as pointed out at p. 188, the "explosive action" is manifested at close range. Symptoms. — Apart from those due to intracranial complications (p. 569), there are no symptoms specially indicative of a fracture of the vault of the skull. The diagnosis rests on the history of injury, on the symptoms due to complicating intracranial lesions, and on physical signs. A skiagraph may be of value. If there is no scalp wound, the entire calvaria must be palpated carefully and persistently to discover any evidence of fracture; if a mere fissure exists, without depression or separation, nothing will be detected beyond the signs of contusion of the scalp (p. 551). The error of mistaking a hema- toma for a depressed fracture must be guarded against. If there is a depressed fracture it usually is possible to feel it tlirough the scalp, recognizing its jagged outline and its actual depression below the surrounding bony surfaces; the depressed fragments may not be impacted, and injudicious pressure may drive them against the brain. If the existence of a fracture remains in doubt, no hesitancy should be felt in making an incision down to the bone, under proper anti- septic precautions, and inspecting the bared cranium. In compound fractures it may be necessary to enlarge the existing wound for the same purpose. A normal suture may be distinguished from a fissured fracture by its anatomical position, its greater irregularity of outline, and by the fact that a fracture cannot be washed clean of blood. In children there may be diastasis of suture lines instead of, or in addition to, fissured or depressed fracture of the skull. ^ Prognosis. — This is good, so far as the fracture alone is con- cerned. It is only intracranial complications that render the outcome doubtful. Excessive loss of bone seldom occurs, and complications affecting the scalp (erysipelas, etc.) are very rare with antiseptic methods. ^See footnote, p. 561. ISJIRIES OF THE SKILL 'yiW Trcdfinrnf. — EvtTv case of liead injury, no matter how trivial in appearance, should he treated with extreme circumspection. It is the custom of many cautious surjjeons, and for .\-ears has been mine, to urjije all patients with injuries of the head to remain under constant surgical observation, preferably in the hospital, for several days. It is most important to prevent infection; and, as a rule, it is well to shave the entire scalp, as this often renders diagnosis easier, and always promotes asei)sis. Shaving the scalp, or at least a wide area around the injury, therefore, usually is the first step in treatment. // onI}/ a fdinpJr fissured fracture exists, without depression, and without any c\idcnce of intracranial mischief, it is sufficient to keep the j)atient in bed for six to eight days, with an ice l)ag to the head; the bowels should be well opened, preferably by calomel, as this has a specific action upon the meninges and brain, exerting w^jat was known in the last century as an "anticipatory antiplastic action," that is, pre\enting excessive inflammatory reaction, probably by its antiseptic properties. Urotropin is used for the same purpose, as it has been found to circulate in the cerebrospinal fluid; it must be given in very large doses. If the simple fissured fracture was caused by localized violence, which is rarely the case, it will be safer to ascertain whether or not the inner table is splintered, by removing a button of bone with the trephine. If such splintering exists, the case is treated as a depressed fracture. If the fissured fracture is compound the surgeon should make very certain that no hair or other foreign body is caught in the fissure, or has passed through it, before he decides against operation. If there is any doubt as to the surgical cleanliness of the fissure, the surgeon must take means to render it aseptic as soon as the patient recovers from the shock of the accident. Sometimes little tufts of hair are found sticking up out of almost invisible fissures (G. G. Davis, 1910), and a gouge must be employed to remove them and their containing bone; in other cases a trephine may be used to per- forate the skull, and then the entire septic fissure is gnawed away into healthy bone by rongeur forceps.' // the fracture is depressed I believe operation always in indicated, to relieve pressure on the brain; and if it is compound, whether it is depressed or not, operation usually is necessary to secure asepsis of the wound. But operation has no virtue of its own, being only a mechanical means of fulfilling plain therapeutic indications. Loose ' In 1907 I operated on a boy of eleven years, at the Episcopal Hospital, Phila- delphia, for extensive bursting fracture due to crush; there were compund com- minuted depressed ring-fractures in the right parietal and the left temporal bones, the poles of impact; and these areas were connected across the vault by a meridi- onal fissure which was deflected into the suture lines, causing diastasis of the right temporo-parietal suture and the entire coronal suture, with rupture of the long- tudinal sinus. The loose fragments were removed, the depressed fragments elevated, and the separated sutures cleaned of hairs and clot by gnawing away both margins of bone. From the left temporal region a fissure ran to the base, thus practically separating the skull into antero-posterior halves. There was no injury to the brain, and the boy recovered. 36 502 SURGERY OF THE HEAD fragments are removed, and the elevator (Fig. 614, 3) is passed under the depressed fragments and these are pried up into place. Search is then made by Horsley's dural separator (Fig. 614, 2) for loose frag- ments which sometimes are driven under the neighboring intact por- tions of cranium, and these are removed. All fragments completely detached should be removed entirely; they will not reunite if left in place, and may undergo necrosis or cause infection. At best they would act only as decalcified bone might, as an inorganic basis into which surrounding osteoblastic cells might grow. If the fragments are impacted, so that none of them can be removed, and there is no crack into which the elevator can be insinuated, a button of bone must Fig. 614. — Instruments used in operating for fracture of the skull: 1, Crown trephine; 2, Horsley's dural separator; 3, bone elevator; 4, Hopkins's rongeur forceps. be removed by the crown trephine (Fig. 614, 1), and the remaining depressed fragments ele\'ated through the opening thus made. Next, the bone must be disinfected. Usually this is best accomplished by biting oflF ragged edges of bone with the rongeur forceps (Fig. 614, 4), thus completely removing all suspicious areas in which foreign par- ticles may have been caught. In fractures of the frontal siiwses the outer w^all alone may be fractured; but as the sinuses are of uncer- tain extent, even when developed, and as the fracture always is compound, either from within or on the skin surface, it is proper to explore the region affected, and to remove sufficient bone to render the wound surgically clean. After any operation for fracture of the skull, a copious dressing INJURIES OF THE SKULL o(J3 should be securely applied (Fig. 015), as the patient may he delirious, and reciuires mechanical protection to the site of operatif)n. liupturc of the longitudinal sinus is a not infrc(iuent complication of fractures of the cranial vault. H. K. Wharton (1901) collected 70 case reports. Bone fragments may be embedded in its walls, or it may be torn accidentally in elevating or removing depressed fragments. Hemorrhage may be profuse, but it is readily controlled by packing, as the blood-pressure is low. Attempts to suture the rent rarely are successful, the sutures tearing out; and the profuse hemorrhage may cost the patient his life before the attempts to suture are abandoned. Packing is quicker and safer. The gauze should be removed in three or four davs. ^ ■ Fit:. 61.5. — Dressing for fracture of skull. Episcopal Hosijital. Trephining the Skull. — The trephine is applied first with the centre- pin protruded; with this as a pivot a circular groove is cut by alter- nately supinating and pronating the hand, and when this groove is of sufficient depth to steady the trephine without the aid of the centrepin this is withdrawn, and the trephining is continued very cau- tiously, using scarcely any pressure for fear of plimging the instru- ment into the brain. The use of Gait's conical trephine' renders this accident unlikely, if ordinary prudence is exercised. When the diploe is reached, the trephine cuts more easily, and the bone bleeds more; as the vitreous is approached the surgeon, from time to time, should test the depth of his groove with the fiat end of a probe, as the skull is not of uniform thickness and incautious trephining may rupture the dura at one side before the vitreous table is cut through on the other. If the button of bone does not come away in the crown of the trephine, it is pried out by the elevator. The trephine never should be applied on the depressed fragment, but on the surrounding intact cranium, so that no further impaction or cerebral injury may be produced. Nor should the trephine be applied directly over the longitudinal or lateral sinuses. Hudson s Trephine (1909) is a modification of Doyen's burr (1896), an instrument like a carpenter's brace and bit; the burrs of Hudson's 1 Thi.s was a revival of an old instrument. Gait's pattern was first used by Sayre in 1861 : the spiral grooves on the periphery act as a wedge so long as there is counter-pressure by bone on the oblique teeth of the crown; when resistance ceases, the spiral grooves act as a screw, and the trephine binds. Hudson's trephine (p. 588) is constructed on the same principle. 5()4 SURGERY OF THE HEAD instrument (Fig, 628) are made with spiral cutting grooves, so that unless something solid like bone is pressed upon by the point, the instrument will bind, thus rendering imj)ossible an injury to the dura. This is the same principle on which Gait constructed his conical trephine. Fractures of the Skull in the Newborn. — Indentations of the semi- membranous skull of the baby may occur from injury during labor, or at a later age from blows, falls, etc. The bone is so flexible that true fracture during labor is rarer than bending. The depression usually corrects itself within ten days; if it does not, and immediately if it produces symptoms of cerebral compression (p. 570), operation should be done. Nicoll's operation (190.S) consists in excision of the cup-shaped depression, and its replacement with the dural (convex) surface beneath the skin. Usually it is sufficient to pry the bone up by an elevator introduced through a neighboring fontanelle or suture. The bone is soft and easily cut by scissors. Some surgeons use a corkscrew for an elevator. The danger of leaving such fractures untreated is that cortical lesions may result, leading to spastic par- alysis, epilepsy, imbecility, etc. Commandeur (1910) has collected 46 such operations, with three deaths from infection. In older infants fracture may split the cranial bone radially in the usual line of ossification. Fractures of the Base of the Skull.— Most of these are the result of bursting force, a fissure extending from the point of injury on the vault to the base of the skull, usually along definite lines. The recognition of this fact is due chiefly to Aran (1844), who claimed that in every fracture of the base the fissure began in the vault. This, how- ever, is not literally true, as the fracture sometimes begins at the base and may or may not extend to the vault. Falls on the feet or on the buttocks may fracture the base by force applied through the condyles of the occipital bone. When fracture of the base occurs as part of a bursting fracture from diffused force applied to the cah-aria, the fissure extends to the base by the shortest anatomical route, avoiding buttresses such as the mastoid, the external angular pro- cess of the frontal bone, etc. Thus it is found that in fractures from lateral compression, usually on the parietal bones, the fissure crosses the middle fossa of the skull in the majority of cases (23 out of 32 cases recorded by Archibald). From Fig. 61G. — Diagram allowing the usual course taken by fissured fractures of the base of the skull. INJURIES OF THE SKULL 565 occi pita-frontal compres.s'ion, a fissure results which passes usually thr()U<:;h oue orbital plate of the frontal, through the body of the sj)iuMioi(l, and the sella turcica, along the petro-occipital suture to the jugular foramen, and perhaps up again to the vault along the niasto-occipital suture; or if the fissure passes down the occipital bone, it skirts the side of the foramen magnvnii, and so to the sella turcica (Fig. ()1()). Uawling found the sphenoidal sinus fractured in 70 per cent, of his cases. These basal fractures very often are com- pound, through the nas()-i)harynx or middle ear. Displacement is very slight. Punctured fractures of the base of the skull are exceedingly serious lesions; they occur from such implements as umbrella tips, pencils, pipe-stems, etc., which may penetrate the orbit or naso-pharynx, sometimes entering one of the fissures or foramina at the base of the brain with little damage to the surrounding bone. Symptoms. — These depend, as in fractures of the vault, much more upon cerel^ral injury than upon the mere existence of fracture. The diagnosis, therefore, depends in large measure on circumstantial evidence derived from certain physical signs, and from a knowledge of the mode of injury. Fractures of the anterior fossa may be accom- panied by bleeding into the retrobulbar tissues of the orbit, sub- conjuncti\al ecchymosis appearing some days after the injury, and spreading from behind forward; exophthalmos is a rare sign. Bleed- ing from the nose or mouth is as often due to extracranial as to cranial lesions. Brain substance or cerebrospinal fluid rarely is discharged. Blood may be swallowed and vomited. Fractures of the middle fossa frequently are compound through the middle ear, and though bleed- ing from the ear may be due merely to rupture of the tympanic mem- brane, when persistent or profuse it has usually an intracranial source ; it may enter the throat through the Eustachian tube. A clear liquid discharge may occur from the mastoid cells or from the membranous labyrinth, but any such discharge in large amount is more apt to be cerebrospinal fluid. Paralysis of one or more of the cranial nerves is more frequent in fractures of the middle fossa than in those of the anterior or posterior fossa^. The seventh and eighth nerves are those most often injured, usually from laceration or secondary edema. Ferron (1908) collected 339 instances of nerve lesion, with 33 deaths. Fractures of the posterior fossa frequently are not recognized, because of lack of physical signs. Ecchymosis over the mastoid, appearing some days after the injury, is of some significance; as is the occasional involvement of the ninth, tenth, and eleventh nerves. Prognosis. — This depends upon the presence of intracranial lesions and upon the development of complications, especially meningitis. Without these, the prognosis is no worse than in fracture of the vault. As a general rule, about one out of three or four patients with fracture of the base will die within a week or ten days. Treatment.— The general treatment is the same as in fractures of the vault: physical and mental rest, in a cool, darkened room; 500 SURGERY OF THE HEAD and purgation to remove material which might cause toxemia or bac- teremia and hence increase the danger of sepsis. Urotropin should be administered (15 grains tliree times daily, with an interval of one day at the end of each three-day period), and liquid diet should be continued until danger of complications has passed. The naso-pharynx and external auditory meatus should be cleansed, but repeated irrigation is more apt to encourage sepsis than to prevent it. If bleeding is profuse it may be necessary to pack the naso-pharynx or auditory meatus; in all cases it is well to keep a little sterile ab- sorbent cotton in the latter channel to absorb discharges. If bleeding is very persistent, and especially if packing produces symptoms of cerebral compression, attempt should be made, by trephining the skull low in the temporal region, to reach the source of hemorrhage and deal directly with it. If symptoms of compression arise, whether there is external hemorrhage or not, decompression should be done (p. 589). Nassau (1912) not only does decompression, but opens the dura, and lightly packs the arachnoid spaces with gauze; he claims that this is the only efficient method of controlling intradural hemor- rhage (p. 575). Four days later the patient is again anesthetized, the gauze is removed, the dural flap sutured, and the scalp closed. Lumbar puncture may be employed as a diagnostic measure to ascertain the presence of blood in the cerebrospinal fluid; occasionally it is curative also. Osteomyelitis. — Osteomyelitis of the cranial bones is rare, and extremely fatal ; usually it follows contusion of the bone, secondary infection occurring through the blood-stream or from an overlying hematoma. It is rarer still as a complication of compound fracture or a scalp wound, as in such cases drainage is free. The diagnosis rests on the appearance of septic symptoms, after injury to the skull, with the develop- ment locally of the "puffy tumor" of Percival Pott (1708), which is "a circum- scribed, flattened, elevated swelling," due to infiltration of the scalp with serum, and indicates "a subjacent sup- purative periosteitis, denuded bone, and in many instances subcranial suppura- tion with separation of the dura mater" (Nancrede, 1885). Treatment. — Treatment consists in removal of all diseased bone, by trephine and rongeur, with free drainage. Death is the usual outcome of the disease, from meningitis and encephalitis, except where very early operation is done. Fig. 617. — Loss of bone after fractured skull: four months after operation. (Dr. Mutschler's case.) Episcopal Hospital. CRANIO-CKREHRA L TOI'Odh'A I'll Y ')()7 Repair of Cranial Defects, rsuallv alter operation for fracture or other lesion of tlie skull, in which a lar^'c area of hone is removed, the defect produces little inconvenience, beinj;; filled in by dense fibrous tissue. Tliere is no tendency to liernia cerebri (Fi^. (iiil ) unless intracranial tension is increased; on the contrary, the area usually is depressed (Fifj;. ()17). Sometimes, from dural adhesions, or other cause, this depressed area is a source of constant aimoyance, and may subject the brain to slight injuries. If the symptoms are so severe as to d(>mand relief, a pedunculated osteoplastic flap, composed of scalp and outer table of the skull, may })e raised by chisel from the neighboring healthy bone, and implanted into the defect (Konig, IsyO), the denuded cranium being covered by a Wolfe graft; or, as done by Frazier in a recent case at the Episcopal Hospital, a free trans])lant, consisting of the outer table, may be removed from another portion of the skull. SURGICAL AFFECTIONS OF THE BRAIN AND MENINGES. Cranio-cerebral Topography, which implies a knowledge of the relation of intracranial structures (cerebral fissures and convolutions, blood-sinuses, meningeal vessels, etc.) to the overlying skull, is not now regarded as of so much importance as some years ago. This is so both because these relations exhibit variations in different persons, and because modern surgical technique enables the surgeon to raise a large bone flap from the cranium, and expose the underlying structures over a sufficiently wide area to permit of his recognizing them rather by their relations to each other than by their relations to the surface of the cranium. But there are a few landmarks which it is indispensable for the surgeon to know. The longitudinal simis runs beneath the sagittal suture from the root of the nose to the inion; it lies within the falx cerebri, and extends, with its annexed blood-lakes, for nearly an inch each side of the median line, being broader behind than anteriorly. Usually it extends further to the right than to the left of the median line. The lateral sinus runs on each side, along the attachment of the tentorium cerebelli, from the inion to the base of the mastoid; here it passes dowmward, following the petro-mastoid suture to the jugular foramen (Fig. ()19). The anterior and upper margin of the curve wdiere the horizontal and descending (sigmoid) portions of the lateral sinus meet, known as the knee (genu) of the lateral sinus, is about 2.5 cm. (1 inch) above and nearly 4 cm. (about 1^ inches) behind the centre of the external auditory meatus. The sinus is about 12 mm. (I inch) or more broad, and the "dangerous area," over which a tre- phine or chisel should not be applied, includes a strip of bone nearly 2.5 cm. (1 inch) wide, overlying the course of the sinus. The upper limit of the cerebral hemispheres corresponds to the position of the superior longitudinal sinus. Their lower limit reaches, in front to the upper margin of the orbit; laterally it passes from a 568 SURGERY OF THE HEAD point 12 mm. (| inch) above the external angular process of the frontal bone, to the upper margin of the external auditory meatus, and thence to the inion, along the upper border of the lateral sinus. The fissure of Rolando runs from a point about 12 mm. (| inch) behind the mid-point between glabella and inion, forward for nearly 8.5 cm. (8| inches), at an angle of about 70° with the sagittal suture. If a square of paper (90°) is folded diagonally, so as to make two angles of 45° each, and one of these folds is again doul)led on itself, so as to make two angles of 22.5° each, it will be possible, by adding one of these latter angles to the 45° angle, to construct off-hand an angle of (')7.5°, or three-quarters of the original right angle. If, then, this Fig. 618. — Relation of the chief fissures and convolutions of the brain to the surface of the skull. The dotted line which is nearly horizontal indicates the fissure of S.vlv^ius; this line runs from the external angular process of the frontal bone through a point 2 cm. below the parietal eminence (x), and its middle third corresponds roughly with the Sylvian fissure. Note the positions of the cranial sutures. angle (07.5°) is placed on the sagittal suture, so that its apex lies 12 mm. (I inch) behind the mid-point between glabella and inion, the course of the Rolandic fissure will be approximately indicated (Chiene, 1888). The relation of the other chief fissures and con- volutions is sufficiently indicated in Fig. ()18. The middle vieningeal artery, entering the skull by the foramen spinosum, divides almost immediately into two branches. The anterior branch runs forw'ard and upward and crosses the anterior inferior angle of the parietal bone, near the pterion; thence it runs upward toward the sagittal suture, lying behind and more or less parallel to the coronal suture. Near the pterion it lies usually in a bony groove or canal, and is frequently torn by splinters of bone, or ruptured CONCUSSION AND CONTUSION OF THE BRAIN 5G9 \)\ iiilu'iidiii^' or l)iirstiiif,' fractures at this point. It may also be iiijuri'd at this |)()iiit 1)\ a trcpliiiie, so it is safer to expose it by a trephine openin*,' in the niiddk' of tlie temporal fossa, say 4 em. (1^ inches) posterior to the e.xternal anj^ular process of the frontal bone, and 2.5 cm. (1 inch) above the zygoma (Fifj. (ill)). The pos- terior branch runs iiori'/ontally backward across the scjuamous plate of the tcni])oral bone, and crosses the teniporo-i)arietal suture within about 2 cm. (f inch) of its posterior end; it may be exposed by a trephine opening; about 2. .5 cm. (1 inch) below the parietal eminence. Fig. 619. — Course of middle meningeal artery and lateral sinus, outlined upon the surface of the skull. Concussion and Contusion of the Brain. — The brain is an incom- pressible structure suspended within a bony case by fibrous partitions, chief of which are the falx and tentorium; it is held relatively immobile at its base by the cranial nerves, bloodvessels, and processes of dura mater, which pass through the base oi the skull. It is surrounded by a small amount of cerebrospinal fluid, which is in greater quantity toward the base, especially around the medulla; and its ventricles, which are directly continuous with the subdural spaces (p. 555), are filled with the same fluid. A blow upon the head causes not so much a vibration or tremefaction of the brain substance, as a sudden displacement of the brain as a whole; it is flung, as it were, against the opposite side of the skull, and usually it is contused most at the point of impact, or the polar point, or at the base, where the greatest strain comes. The cerebellum is relatively little affected, because of its protected position beneath the tentorium, because it floats on a greater amount of cerebrospinal fluid, and because of the possi- bility of downward displacement by crowding the medulla into the foramen magnum. Some blows on the head, severe enough to cause symptoms, produce symptoms which are so momentary and fleeting that it always has been difficult to believe that they were attended by structural change. And until modern methods of histological study were developed, it happened not rarely that postmortem 570 SURCERY OF THE HEAD examination failed to disclose any lesion in the brains of those who had actually died with symptoms due to "concussion." But it has come to be recognized, largely through the investigations of Sir Prescott Hewett (1870), that the condition of these brains is not one of "concussion," as was formerly taught, but is the result of con- cussion, and is characterized by contusion, compression, extravasation, laceration, or inflammation in varying degrees. Of course, it cannot be asserted categorically that histological changes always are present in patients who recover at once from the symptoms of concussion, because there is no opportunity of submitting their tissues to micro- scopical examination at the time of injury; but the belief is quite general, and I believe quite justified, that even when the symptoms produced are the most insignificant, definite lesions exist, and that these vary from temporary arrest of cell-action, with capillary stasis, or the slightest grades of contusion, with punctate hemorrhages, to distinct laceration, ecchymosis, exudation, and edema of the brain and pia-arachnoid. Kocher teaches that the immediate and temporary symptoms are the result of cerebral anemia, while uncon- sciousness which lasts for hours or days is due to cellular changes. Symptoms.-^As in all cases of injury, some degree of shock is present, and it often is difficult to distinguish the symptoms of this condition from those due to concussion of the brain. After a blow on the head only such symptoms as dizziness, or disturbances of vision (sparks, specks, etc.), may be observed. In more marked cases there is momentary loss of consciousness, the patient falling as one dead; or, when striking the head in a fall, lying motionless for a few seconds, and then regaining consciousness and rising to his feet before assistance can reach him. In typical cases, two distinct stages may be recognized:^ (1) The patient at first lies motionless, senseless, nearly pulseless, pale and cold, breathing feebly but natur- ally; the pupils dilated or contracted, fixed or acting freely; perhaps with involuntary discharge of feces and urine. He will swallow if food is put into his mouth. From this first stage, which may last many days, the patient may recover without further trouble, or he may gradually sink and die without reaction; or the first stage may last a few moments only, the patient having passed into the second stage before the surgeon sees him. The disappearance of the first stage, whether by passing into the second or by direct recovery, commonly is marked by vomiting, (2) In the second stage the patient is no longer unconscious, though much indisposed to speak or pay attention to surrounding objects. If roused by a question, he will answer, but peevishly or angrily, turning away as if displeased at the interruption. His posture is peculiar: he lies habitually on his side, curled up, with all his joints more or less flexed, and if a limb is touched he draws it away with an air of annoyance. The eyelids are kept firmly closed. The pulse, at first slow and weak, gradually ' This description is copied, almost verbatim, from the Principles and Practice of Surgery- of John Ashhurst, Jr. COMPRESSION OF THE HRAIN ')71 becomes more frequent and stronger; the l)reatliinfi; is easier, and the surface regains its natural warmtii and color. This staj^e gradually subsides, after se\eral hours or days, and as the patient rej^ains ability and willingness to communicate with those around him, he complains almost invariably of severe headache. If the cerebral lesions have been marked, they may leave the j)atient with his mental faculties permanently impaired; usually, however, in such an event, the earlier symptoms will have been those of compression of the brain rather than those recognized as due to concussion. Treatment. — The patient should l)e laid horizontal, with the head slightly elevated, in a darkened room; and throughout his illness he should be protected from all noise. During the first stage, stimu- lation for shock may be necessary. So soon as shock is recovered from, the bowels should be evacuated, the urine drawn if necessary; and moderate amounts of liquid nourishment should be administered. During the second stage, cold should be applied to the head, while restoration of cerebration may be hastened by the administration of calomel, one-sixth of a grain every four hours, for its "anticipatory antiplastic effect" (p. 561); and this may be continued for many days, or until the patient is clear in his head. Should restlessness or delirium supervene, it is well to administer, with each dose of calomel, two or three grains of Dover's powder. The use of the mind, in conversation, reading, etc., should be resumed very gradually, and convalescence should be prolonged, the patient living by rule for many months after apparent recovery, and remaining under surgical observation until by the lapse of time the absence of com- plications from unrecognized cerebral lesions is assured. Compression of the Brain. — As already stated, the brain is an incompressible structure; its bulk can be reduced only by loss of its fluid constituents; if compressed in one direction it must expand in another. Experimental compression of the brain produces first a stasis in the smaller venous channels; the longitudinal sinus col- lapses; the blood cannot escape from the skull. If pressure increases the arterioles may be affected. Normally changes in intracranial vascular pressure are compensated for by the ebb and flow of the cerebrospinal fluid. This drains away into the veins, and these in turn empty mostly into the longitudinal sinus and certain emissary veins through the diploe. Increase in vascular pressure from the arte- rial side is easily and rapidly compensated for by venous absorption of cerebrospinal fluid; and obstruction to the venous outflow (often seen in cases of cervical or thoracic neoplasms) does not prove inju- rious so long as the collateral diploic veins are open, or so long as the cerebrospinal fluid can pass into the spinal canal and escape into the venous circulation by that channel. But if the pressure on the venous side becomes so great as to dam the blood back into the capillaries, these side escapes become blocked, the brain may be forced dowm until the medulla chokes off the outlet for cerebrospinal fluid through the foramen magnum, and symptoms of "compression" appear. 572 SURGERY OF THE HEAD It was shown experimentally by Althann, in 1871, and since his time by numerous other investigators, that "the effect of space diminution in the skull was identical with that of any other process which hindered cranial circulation" (Archibald, 1908); so that, as pointed out l)y von Bergmann (1880), the symptoms of "compression" are due not to actual compression of nerve elements, but to cerebral anemia. The maintenance of life depends on the functioning of the chief medullary centres, ^'as()motor, vagus, and respiratory; and it is to interference with the circulation of these centres that the most strik- ing symptoms of cerebral compression are due. Localized compression produces the so-called focal symptoms, i. c., paralysis; while general- ized ■ compression, which may develop independently of, or may succeed, local compression, is particularly characterized by bulbar symptoms: interference with the centres already named; but in generalized compression there also usually is unconsciousness, from cortical compression. So soon as anemia affects the medulla, the vasomotor centre is stimulated, blood-pressure is raised higher than intracranial (extra- vascular) pressure, blood again reaches the medulla, and life is pro- longed, at least temporarily (von Schulten, 1885). But the stimulus of anemia then being removed, blood-pressure sinks somewhat, as intracranial pressure continues to increase, and anemia of the medulla again occurs; whence renewed stimulation of the vasomotor centre, a further rise in blood pressure, and again a temporary relief of the medullary anemia. Cushing (1902, 1^0-3) has been able to follow these successive periods of anemia and return of circulation by obser- vation of the cerebral cortex of monkeys through a trephine opening; and his experiments justify the conclusion that similar changes occur in the medulla. This alternate stimulation and depression of the medullary centres explains the more or less periodic phases observed in the blood- pressure and respiration curves obtained from such patients. They are known as Traube-Hering waves. The respiratory phases closely resemble the Cheyne-Stokes type, the stage of apnea occurring when the respiratory centre is deprived of blood, and the hyperpnea develop- ing when circulation is restored by increase in blood-pressure. This "life and death struggle," as von Schulten termed it, may continue until blood-pressure reaches enormous heights; Cushing raised it experimentally to 290 mm. Hg.; but unless intracranial pressure is relieved, the medullary centres in time will cease to react, and sudden fall of blood-pressure will occur, followed by death. "Death probably always occurs from primary failure of the vasomotor centre, rather than from that of the respiratory, as has been asserted by some. The vasomotor centre holds the key to the position. Its defeat involves that of the respiratory and vagus centres; and with their defeat the whole armv is devoted to slaughter." (Archibald, 1908.) COMPRESSION OF THE JiliAIN nl'.^ Causes. — Anything; which increases iiitracrania] pressure may cause symptoms of compression of the brain. This inchides: (1) Foreign bodies driv'cn against or into the brain (bone fragments, l)ullets, etc.); (2) hemorrhage, subcranial, sub(hiral, or intracerebral; (o) pro(hiets of iiiiiammatiou (serous cfrusion, lymph, pus); (4) tumors of tlie brain; (o) accpiired internal hydrocephahis, etc. Symptoms. — ^'ery sK)wly induced compression ma\' not produce symptoms for a h)ng period; and even in cases of rapid compression tliere often is' a ".s7ar/r of conipni.'iation'' from rise in blood-pressure, during which no symptoms may be observed. During the sfaf/r of manifest comprcfision two periods may be recognized: (1) Karly sipnpioms: There is irritation of the cortical and medullary centres, due to venous stagnation; slight quickening of respiration, and rise in blood-pressure; headache, dizziness, restlessness, roaring in the ears, disturbed sleep; moaning and groaning; and at times delirium. Sometimes circulatory changes in the fundus oculi can be detected, but these disappear in a few hours. (2) Late symptoms: The gradual increase in the compressing force finally overcomes the blood-pressure, and cerebral anemia results. This stimulates the vasomotor centre which raises blood-pressure yet higher by causing peripheral capillary constriction, especially in the splanchnic area. The patient lies somnolent, stuporous, even comatose; with slow, full, bounding pulse; there is labored respiration, which in the last stages approaches the Cheyne-Stokes type; the cheeks are passively puflFed out at each expiration ("smoking his pipe," the French call it); the pupils react sluggishly or not at all. The more dilated pupil usually is on the side of greatest compression. Sometimes the patient can be partially roused from his coma by pressure on the supra-orbital nerve; then slight convulsive movements of the extremities may occur, and hemi- plegia, or localized paralysis may become evident. Irregularity of the respiration is one of the earliest and surest signs of approaching exhaustion of the medullary centres; and unless blood-pressure can be measured periodically by the manometer, respiration is a more reliable guide as to prognosis than the quality of the pulse; for the "vagus pulse," slow% regular, and strong, continues practically unchanged until very near the fatal ending. Diagnosis, — If the early symptoms of the stage of manifest com- pression were borne in mind, the condition often could be diagnosed and measures for relief instituted, before the later stage, complicated by unconsciousness, is reached. When an unconscious patient is examined, the existence of an adequate cause for cerebral compres- sion always should be excluded before dismissing this as the cause of the symptoms. ]\Iany a patient suffering from cerebral compression has been sent awa}' from accident wards as "drunk," when a very little time spent in examination would have detected focal symptoms (pupillary, facial, or lingual paralysis; monoplegia, hemiplegia, etc.); while bulbar symptoms probably could have been discovered if they had been specifically looked for. In any case of doubt, keep the 574 SURGERY OF THE HEAD patient under observation; if the cause of symptoms is compression, this soon will become evident. Prognosis.^ — This depends very largely upon the cause of the com- pression, and the time at which treatment is instituted. In many cases of brain tumor, for instance, it may be impossible to remove the cause of compression, so that cure is out of the question; but symptoms may be relieved and life prolonged by removing the counter- pressure caused by the skull. But even in cases where the cause of compression can be removed, treatment may not be instituted until the last stages of compression, and the medullary centres may not recover; or even though they recover, the focal compression may have done so much damage to the cerebrum as to impair the patient's mental or physical ability throughout life. Treatment. — From what has been said above it is very evident that the two main indications are to maintain blood-pressure at a higher point than intracranial (extravascular) pressure, and to relieve the compression by surgical means. The full, bounding pulse, the singing in the ears, etc., of the early stages, do not by any means indicate that the patient should be bled, or that aconite should be administered; they are an index of his compensatory powers and all that will save his life is to keep his blood-pressure high, and to relieve the intracranial pressure as quickly as possible. Theoretically the latter point may be gained by lumbar puncture of the subdural space of the cord; but draining away cerebrospinal fluid, by removing the brain's support from below, may serve only to allow the super- incumbent pressure to force the medulla down into the foramen magnum, thus strangulating it and causing instant death. The most imperative indication is to "decompress" the brain by removing some of the overlying cranium, on one or both sides. This may be done by the trephine, the opening being enlarged by rongeur forceps, or a bone-flap may be raised (p. 586). At the same time that decom- pression is done, the cause of compression, whenever possible, should be removed. The site of the cranial opening depends on the cause of compression and on the existence of focal symptoms; when not contraindicated the subtemporal operation of Gushing (p. 590) is very satisfactory. In the most advanced stages of cerebral compression emergency measures are necessary to raise the blood-pressure until operation can be undertaken; these are such methods as artificial respiration, lowering the patient's head, bandaging his extremities, compression of the abdomen, and the administration of strychnin, adrenalin, etc. After decompression it should be remembered that the stimulating effect of recurring anemia upon the vasomotor centre is lost; and if this centre shows signs of exhaustion, it must be stimulated by str.ychnin, or repeated doses of adrenalin. Subcranial or Extradural Hemorrhage may be due to bleeding from the diploe or cranial sinuses, in cases of fracture of the skull, but in the vast majority of cases it is due to rupture of the middle COMI'lil'JSSION OF TIll'J lih'AIN i^ti^ incniiiiijciil artery. Middle iiirn'ni(i<'(d IwiiiorrlKuje may occur with or without fracture of the skull, aud upou the side of iujury or ou the opi)osite side (from "contre-coup"). The anterior l)raneh of the artery is most often ruptureci, usually near the pterion, where it passes throujjjh a bony f^roove or canal; but it may be torn off at its exit from the foramen spinosum (by concussion, or by a burstinjj; frac- ture), or lacerated by bone fragments at other i)arts of its course. The bleeding which results slowly sepa- rates the dura from the cranium, and the resulting clot may spread over an entire hemisphere (Fig. ()2()). Diagnosis. — The usual history is that after an injury to the head the patient experiences momentary symptoms of concussion, then re- covers more or less completely ; but some hours or even days later signs of compression appear, sometimes gradually, sometimes with alarming suddenness. What is particularly characteristic is the so-called "free interval," between the injury, when rupture occurs, and the time when the accumulating clot brings on symptoms of compres- sion. Treatment. — The treatment consists in exposing the main trunk or anterior branch of the artery, removing the clot, tracing the bleed- ing to its source, and ligating the artery by passing a fine suture around it by means of a round-pointed needle. T. R. Neilson (11)03) plugged the foramen spinosum wdth a match-stick. If the hemorrhage does not come from the anterior branch, the posterior should be exposed. If all focal signs are absent, and no cause for compression is found on the side of the skull first opened, it is justifiable to open the other side, as rupture may occur from counter-stroke. Intradural Hemorrhage. — Bleeding into the meshes of the pia- arachnoid, which is much more frequent than the extradural form, almost invariably is of traumatic origin, venous in character, and complicated by extensive cranial and cerebral injury (Fig. 021). Usually the blood is widely diffused, and the fluid removed by lumbar puncture may be blood-tinged. The symj)to7ns are those of cerebral compression; "it is safe to say," writes Gushing, "that in anj^ serious cranial injury in which unconsciousness has been present from the first, subdural bleeding is taking place, either from the fracture itself or from some laceration of the brain." Treatment consists in decompression if symptoms of compression continue for more than a Fig. 020. — Subcranial hemorrhage from rupture of the posterior branch of the middle meningeal artery. No frac- ture of the cranium. Man, aged fifty- one years, was found lying on the street, unconscious. Taken to police station. Operation about forty hours after in- jury. Blood-pressure fell from 170 mm. before operation to 110 mm. a few hours later. Recovery. Episcopal Hos- pital. 576 SURGERY OF THE HEAD few hours or are well marked at first. Seldom is it possible to find any distinct bleeding point, but exposure to the air, or gentle irriga- tion with very hot saline, may be sufficient to arrest the hemorrhage. Drainage is provided by strips of rubber tissue. The operation, unless another opening is indicated by focal symptoms, should be by Cushing's subtemporal route (p. 590) which gives ready access to the base of the brain whence the bleeding usually arises. As already mentioned (p. 566), Nassau tampons the subdural tissues for four days, then replaces the dural flap. Fig. 621. — Intradural hemorrhage. A boy of five years had a large flap of scalp torn loose. Parietal bone bent inward, but no fracture. Operation three hours later (for continued unconsciousness and left hemiplegia) showed extensive intradural hemor- rhage, the brain being 4 cm. distant from the dura. After removal of compression respira- tion improved, but death occurred in a few hours. Episcopal Hospital. Intracranial Hemorrhages in the Newborn. — These occur usually from a rupture of a vein in the pia-arachnoid, near the longitudinal sinus, as the result of trauma during birth. The diagnosis is not always easy, at least until signs of compression of the brain appear; lumbar puncture may show bloody cerebrospinal fluid; and cerebral irritability and irregularity of respiration are suggestive. The prog- nosis is bad; nearly 80 per cent, die from cerebral compression within a few days; while of those that recover most are mentally deficient or afflicted with spastic paralysis (p. 530), athetosis, nystagmus, etc. Treatment: Operative relief, proposed by Keen in 1901, was first employed in 1904 by Cushing, who has reported (1908) nine operations, with four recoveries. A large osteoplastic flap, which can be cut out with strong scissors, is raised, the dura is opened, the clots removed by gentle irrigation, and the wound closed without drainage. Intracerebral Hemorrhage occurs chiefly as the result of vascular disease (ordinary "apoplexy"), or from degenerative changes in brain tumors. Wounds are occasionally causes of localized cortical hemorrhage. The suggestion by Leonard Hill (1896) that surgery by effecting decompression, or even by evacuation of the clot, might be of use in these cases, was acted upon with success by Borsuk and SIMS riiiioMiiosis :ui Wizel (I.S97) ill ;i tr;iiiniatic case, ("iisliiiij; (1!)()S) lias ((pcratcd on four cases oF spontaneous lieniorrha^c, one operation (suhtcuiporai decompression and e\acuation ot" tlie clot) heinj^ successful. I'lider expectant treatment the mortality is nearl.x 00 per cent., in these cases of acute severe apoplexy, in which alone is operation to be considered. Sinus Thrombosis. This arises, in the vast majority of cases, by extension of .septic iuHammation from the air sinuses of the skull, especially tlie mastoid cells. Pyoffcnic inflammation of the scalp or erysipelas are rare cau.ses, the infection spreading along the diploic emissary veins. The (licifino.sis depends on reco<;nizinff a focus from which sei)tic inflannnation may be derived, on local sij^ns such as edema of the overlyinj; scalp, and distention of its veins, together with evidences of constitutional sepsis, and perhaps cerebral com- pression. The longitudinal sinns may be thrombosed from frontal, ethmoidal, or si)hen(Mdal sinusitis, or rarely from erysipelas of the scalp, etc. Thrombosis of the cavernovs sinus, which is very rare, may arise from extension of inflammation along the facial and angular veins (carbuncle of upper lip, etc.), or along the petrosal sinuses (from the sigmoid sinus), and is particularly characterized by the resulting exophthalmos. The lateral sinus, especially its sigmoid portion, is that which is involved in by far the largest number of cases, and almost always as the result of middle-ear disease, the infection coming along the emissary veins or directly invading the sinus wall after destruction of the intervening bone. The symptoms are those of the preexisting disease (mastoiditis), of sepsis (repeated chills, sweating, hectic temperature), and cerebral irritation or compression (rare); but such symptoms often do not appear until the sinus thrombosis has been in existence for some days, and may indicate a softening of the clot and dissemination of emboli. Naturally the lungs are most often attacked in this way. Thrombosis is prone to extend to the internal jugular vein, and often this can be felt as a tender cord in the neck. The head may be tilted to the affected side. In meningitis, which is much commoner in infants than adults as a result of middle- ear disease, cerebral symptoms (vertigo, vomiting, hebetude, delirium) are more marked, there is retraction of the neck and paralysis of the ocular muscles, with choked disk; fever is higher and more regular; Kernig's sign is present; and lumbar puncture shows turbid cerebro- spinal fluid, from which organisms may be recovered. In brain ab.scess cerebral symptoms, without those of meningitis, predominate; temperature is subnormal; there is evidence of cerebral compression; and emaciation is rapid. In neither meningitis nor in uncomplicated cases of brain abscess is there thrombosis of the internal jugular vein. Treatment. — The first step is to clear out the mastoid, and this merely preliminary measure should not be done with too great delib- eration (see Chapter XIX). The shell of bone which overlies the sigmoid sinus is then removed by gouge or burr, and the sinus well 37 578 SURGERY OF THE HEAD exposed; plenty of room should be gained by use of the rongeur. The sinus is next incised: if bleeding occurs the sinus is compressed first on the torcular side; and, if it continues, also on the jugular side of the incision. Persistence in bleeding, when pressure is made at both these points, indicates a return flow from the mastoid emissary or superior petrosal sinus. These should be separately tested. If the petrosal is not thrombosed it is probable that the entire system is healthy. 7/ no bleeding occurs when the sinus is opened, it should be slit up toward the torcula until a return flow is obtained; this is controlled by packing; the clot is then removed as far as the original incision, and, after temporary pressure has been made on both jugulars in the neck, a similar procedure is carried out at the bulbar end of the sinus. If no return flow can be obtained from this end of the sinus, it is a sign that the thrombus extends into the jugular, and resection of this vein should be done. It is to be performed as a primary oper- ation, before exposing the sinus, when a diagnosis of jugular thrombosis is made in advance. Resection of the Internal Jugular Vein: The vein is exposed and doubly ligated low in the neck; it is divided between these ligatures and dissected upward, clamping and tying each branch encountered. Thrombosed branches should be excised. When the vein has been traced up as far as possible, it is ligated and cut across. The neck wound is tamponed with gauze and not closely sutured. If the jugular vein is too densely adherent to be removed safely, it should be slit open, and the wound packed with gauze. The general mortality of thrombosis of the lateral sinus is about 25 per cent. Meningitis. — External Pachymeningitis, usuall.y purulent and local- ized (subcranial abscess), affects the external layer of the dura, and may result from osteomyelitis of the cranium (p. 566) with or without fracture of the skull, or from neighboring sinus thrombosis. Treatment consists in removal of the overlying bone, with drainage. Internal Pachymeningitis is a rare disease, of subacute or chronic character, in which membranous lymph, easily detachable, is deposited on the inner layer of the dura. It is microbic in origin, occurs some- times in general infections (typhoid fever, pneumonia), and some- times is hemorrhagic in type. The symptoms are not very character- istic, being those of slowly increasing cerebral irritation or compres- sion; and the diagnosis is difficult. Treatment: operation, comprising removal of the false membrane or hemorrhagic exudate, offers the only hope of cure or prevention of insanity (Munro, 1902). Leptomeningitis. — Inflammation affecting the pia-arachnoid may be due to a number of bacteria; the form known as epidemic cerebro- spinal meningitis, caused by the Diplococcus intracellularis, is a specific contagious disease, usually coming under the physician's care. Early use of Flexner's serum (1906) is most important. As the ultimate cause of death is purely mechanical, being due to cerebral compression from acute internal hydrocephalus (p. 554), surgical treatment may be advisable when purely medical measures have BRAIN ABSCESS 579 failed. Lumbar puucturo, used for diagnosis, is of no therapeutic value wlien liytlroceplialus supervenes; the only remedy is single or rej)eated puncture of the ventricles. Leptomeningitis also may be caused by ordinary pyogenic cocci, pneumococcus, B. tuberculosis, etc. P^specially in tiibrrciiloKS inenin- gitis, which is so uniformly fatal under medical treatment, it seems as if almost any surgical risk were justifiable. Lumbar puncture will relieve the intracranial tension, due to accumulation of sero- purulent exudate, so long as the medulla is not driven down like a cork into the foramen magnum, or so long as the foramina in the roof of the fourth ventricle are patulous (p. 554). But when acute internal hydrocephalus develops, the only hope of relief lies in tapping the ventricles (p. 555) or their permanent drainage into the subdural space (p. 55(i). Serous or Amicrobic Meningitis is a form of the aflection in which clear, sterile serous fluid collects in the intradural spaces (Eichhorst, 1887). Some cases are traumatic in origin, but most are regarded as due to bacterial infection localized elsewhere in the body, thus being analogous, as pointed out by Archibald (1908), to the sterile serous effusion of pleurisy secondary to subphrenic abscess. Some- times this affection complicates sinus thrombosis or mastoiditis. Diagnosi,s. — The diagnosis is difficult, the serous character of the effusion being discovered first at operation undertaken to relieve pressure symptoms thought to be due to subcranial or intradural suppuration, or to brain abscess. Treatment. — In traumatic cases lumbar puncture may suffice to evacuate the fluid; in others craniotomy should be done. If serous meningitis is found, undue persistence should not be exercised in searching for a brain abscess which may not exist. Syphilis of the Leptomeninges. — Practically all the intracranial lesions of syphilis arise in the meninges and involve the brain only secondarily, by pressure. They are found most often in the arachnoid tissues, especially in the frontal region and at the base. The diagnosis from cerebral tumors is not easy, but the treatment is much the same (p. 585). Encephalitis or Cerebritis, except as it complicates traumatic lesions, concerns surgeons little, unless in localized form (Brain Abscess). There is supposed to be an epidemic form, analogous to acute anterior poliomyelitis, of which, probably, more will soon be heard. Brain Abscess. — This is due in about equal proportions to tramna, especially penetrating and punctured wounds, and to supimrative disease of the mastoid cells, middle ear, or other air sinuses of the cranium. It occurs also in pyemia, but very much less frequently. The site of the abscess in the brain depends largely on the focus of infection. Frontal abscess results from disease of the frontal sinuses, ethmoid and sphenoid cells, cavernous sinus, thrombosis, etc. Middle- ear disease is the chief cause of abscess in the temporo-sphenoidal 5S(1 SURGERY OF THE HEM) lobe; while cerebellar abscess usually is secondary to mastoid disease or lateral sinus thrombosis. The causative condition frequently has been in existence for months or even years, before brain abscess develops. The cerebrum is affected more than twice as often as the cerebellum. The abscess almost always is in the subcortical area of the brain, and seldom has any macroscopical connection with the Fig. 622.— Cerebral abscess from mid- dle-ear disease; initial stage: headache, nausea, chilliness, and fever. (G. Laurens.) Fig. 62.3. — Cerebral abscess from middle-ear disease; manifest stage: per- sistent headache, mental hebetude, and other symptoms of compression. (G. Laurens.) source of infection, having arisen from embolism (rare), or by pro- gressive thrombosis of minute venous channels. Usually, if not invariably, however, there exi.sts a microscopic connection between the source of infection in the cranial bones and the abscess cavity; the abscess has been compared to a mushroom, growing by a stalk from the neighboring carious bone. Fn;. 624. — Cerebellar abscess from middle-ear disease, simulating meningitis (retraction of the head, occipital headache, etc.). (G. Laurens.) Symptoms. — AYhen the abscess follows middle-ear disease, which is its most frequent single cause, and may be taken as the type, it is usual for there to have been some recent exacerbation of the chronic symptoms. The course of a typical case is well sketched by Cushing: after the exacerbation of the old symptoms, arise those of the initial stage of brain abscess (headache, nausea, chilliness, and fever) (Fig. BRAIN TVMOR oSl 022); these may subside, hut rarely disappear entirely, for a period iA a week or ten days {latent stage) ; then, with more or less sudden cessa- tion of diseharfje from the ear, symptoms of intracranial sepsis and pressure become evident (i)ersistent headache, mental hebetude, vom- iting, slow pulse, subnormal temperature, and leukocytosis (manifest stagr) (Fig. (528). I'sually there are no distinct focal symptoms, other than marked tenderness of the overlying skull, and sometimes facial ])aralysis. Raj)id emaciation is a very significant sign. If the abscess is in the cerebellum, meningitis may be simulated (Fig. (524). The distinction between abscess and tumor of the brain seldom is difficult (p. r)S:5). Treatment. — The abscess must be drained as early as possible. Do not delay overnight if you suspect an abscess. Some surgeons prefer to do a tympano-mastoid exenteration first, and then wait a few da}s, to see if the symptoms suggestive of brain abscess will subside; but if an abscess is present, any delay is dangerous. IMany operators prefer to open the intact cranium (Macewen, 1893) over the supposed site of abscess, and to proceed to exenteration of the tympano-mastoid only after evacuating the abscess. For abscess in the temporu-sphenoidal lobe trephine at a point one inch above the supra-meatal spine. The cerebellum is exposed by trephining below the lateral sinus and posterior to its sigmoid portion. ]Most aurists think it safer to approach the brain abscess through the middle ear or mastoid, because by this avenue one is most certain to cross the meninges where adhesions exist, and can follow on to the abscess along its "stalk." ^Yhen the cortex is exposed, in either case, measures should be taken to prevent contamination of the meninges, unless the diseased area is isolated already by adhesions. The brain is then explored by a grooved director, and when pus is found the overlying cortex is incised on the director, sufficiently to secure drainage. This is difficult to maintain, as the semifluid brain tends to block the tube. Should damming up of pus be suspected the wound must be reopened. Even in the hands of the most skilled and expert surgeons, operation for brain abscess is attended by a mortality of about 50 per cent.; but as all patients will die, and quite as soon, if no operation is done, this should not deter one from trying to save even moribund patients. Brain Tumor. — Any growth within the cranium, whether a true neoplasm or an infectious granuloma, is considered clinically a "brain tumor," because productive of the same general signs. Tuber- culoma is the most frequent growth in childhood; these tumors occur with special frequency in the cerebellum, and often are multiple. Syphiloma is more common in adults, being usually a meningeal growth which compresses the brain secondarily. These two t}'pes of growth from a larger class of brain tumors than do the true neo- plasms. Of the latter, the most frequent are endothelioma and glioma. The former grows from the meninges, usually is encapsulated and easily enucleated from the cup-shaped depression it produces in the 582 SURGERY OF THE HEAD surface of the brain; the glioma, on the other hand, usually is an infiltrating growth of the subcortical area, and is with difficulty distinguishable macroscopically from normal brain tissue. Sarcoma, which is less usual, grows from the connective tissue of the meninges, frequently invading the bone; or may arise in the cortex, whence it sometimes can be shelled out, owing to peripheral degenerative changes. Often it is multiple, and is a more frequent form of metastatic growth than carcinoma. Fibroma is seldom seen except in the cerebello- pontine angle. Cysts occur in the brain; some are of parasitic origin (echinococcus, cysticercus), others are the result of hemorrhages into the brain substance, or arise as degenerative changes in a glioma. The latter is the usual cause of cerebellar cysts. Symptoms. — Tumors grow in the brain oftener than in any other part of the body. Hale White (1885) estimated that a tumor is found in the brain in one among every 59 autopsies. They may exist for years and cause no symptoms, if in a silent region or if of very slow growth. They occur mostly between the ages of fifteen and fifty. In old age and infancy they are rare. It is usual to discuss the symp- toms of brain tumor under two headings, general symptoms, and localizing symptoms. General Symptoms. — The syndrome of brain tumor comprises the three cardinal symptoms, headache, vomiting, and papilledema. Headache at first is intermittent, but when constant, and especially when referred persistently to one region, which is tender to percussion or pressure, must be regarded as highly significant; probably it is due, as pointed out by Gushing (1908), to pressure upon or distortion of the falx or tentorium, as the brain itself is insensitive. The vomiting, perhaps due to irritation of the pneumogastric nerve, is projectile in character, may occur independently of meals, and be unattended by nausea. Papilledema, optic neuritis, or choked disk, is a characteristic change in the eye-grounds, commonly believed to be due to damming up of the cerebrospinal fluid in the sheath of the optic nerve, as the result of increased intracranial tension. If this pressure is not relieved, hemorrhages may occur in the nerve head and retina, resulting in permanent blindness. Usually both optic nerves are affected, but unequal involvement of the two nerves does not indicate that the compressing lesion is on the side where papilledema is greatest, unless only one nerve is appreciably involved. Papilledema often is more marked in subtentorial lesions than others. The importance of examining the eye-grounds in all suspected cases of intracranial lesion cannot be too much emphasized, as acuity of vision may persist even when papilledema is moderately far advanced. On the other hand, this sign may be entirely absent throughout the course of the disease. Gushing recently has called attention to changes in the color fields, detected by expert ophthalmological examination, as one of the earliest of the general signs of brain tumor. No bulbar symptoms, such as occur in compression of the brain from trauma, are observed in cases of brain tumor, because the increase in pressure BhWI.S TIMOR 583 is so very gradual. Occasionally a hraiii tumor, previously unsus- pected, makes its presence known first by the occurrence of a hemor- rhage into the tumor, the symptoms resembling those of ordinary apoplexy; and in a young adult such an occurrence should rouse the suspicion of a brain tumor. Loralizinr/ Si/mptoms. — These are interpreted through anatomical knowledge of the seat of the cerebral functions. As the increase in pressure occurs very slowly, it is the rule for the development of paralytic symptoms to be delayed, usually being preceded by irritative symptoms (Jacksonian epilepsy, p. oDO); and a very slowly growing tumor in a silent region of the brain may produce no localizing symptoms until by encroachment it involves the nearest physiologically recognizable centre, causing "neighborhood" as distinguished from true "focal" symptoms. Thus a tumor in the frontal lobe may make its presence known only by general symptoms (headache, vomiting, papilledema), until so large as to interfere with the motor functions; and when paralysis of motion at last occurs, the incautious observer may jump to the conclusion that the tumor is growing in the motor region; instead of recognizing the fact, as he would have done if an accurate history of the progress of the disease had been obtained, that the growth evidently was primary' elsewhere, and had compressed the motor region only secondarily. Diagnosis. — This involves not only the determination whether a tumor exi-sts at all, but also the recognition of the kind of tumor present, and its location. 1. Brain tumor may be closely simulated by the cerebral symptoms of chronic nephritis; the urinary changes in the latter condition are the chief distinction, but as a brain tumor may coexist, the patient should be watched for the development of localizing symptoms. Abscess of the brain usually may be distinguished from brain tumor by the history of trauma, bone disease, etc., which is absent in the latter affection; as well as by the more acute course of the disease in cases of brain abscess. Acquired internal hydrocephalus (p. 554) is to be distinguished by the usual bilateral distribution of any local- izing signs. Sometimes a brain tumor may be detected by aid of a skiagraph. 2. llie kind of tumor is very difficult and usually impossible to determine. The existence elsewhere in the body of a tuberculous process naturally would suggest a tuberculoma as the cause of the cranial symptoms; as would a history of syphilis or evidence of past or present S3'philitic lesions the existence of a syphiloma. The tuber- culin tests and the Wasserman reaction are also available. The use of antisyphilitic remedies, as a method of exclusion, though quite habitual, should not be persisted in for more than six weeks (Horsley, 1890), unless relief of symptoms is secured sooner; because, in the first place, few intracranial syphilomas are permanently influenced by medication, and, secondly, other forms of tumor ma}^ undergo temporary regression under antisyphilitic treatment, only to cause 584 SURGERY OF THE HEAD renewed symptoms later. Moreover, it is quite characteristic of the intracranial lesions of syphilis to undergo spontaneous retro- gression and recrudescence, even in the absence of treatment. Lumbar puncture may aid the diagnosis by showing the constant lymphocy- tosis so characteristic of syphilis, or by revealing the tuberculous nature of the affection by appropriate pathological methods. Noth- ing certain can be said of the diagnosis of glioma, endothelioma, sarcoma, etc. 3. The Site of the Tumor. — If in the frontal lobe no localizing symp- toms will be recognized, but there may be certain alterations in intellect appreciable by the patient's family or intimates. P>ontal lobe tumors often are found at autopsy on the insane. A certain degree of incoordination may be present, affecting the equilibrium in standing or walking, and causing resemblance to cerebellar tumors. A tumor in the motor area (anterior to the Rolandic fissure) will produce first Jacksonian epilepsy (p. 590), and later motor paralysis of the opposite side, first of the centres nearest the growth, and later of the entire motor cortex of the hemisphere involved. In the parietal lobe (just posterior to the fissure of Rolando) sensory disturbances (such as loss of muscle sense, posture sense, etc., or word blindness) will precede Jacksonian fits and loss of motion, which latter phenomena will result when the tumor reaches such a size as to press upon the cortex or subcortical fibres in front of the fissure of Rolando. A tumor in the superior parietal convolution may cause astereognosis. A tumor of the occipital lobe, or posterior part of the parietal lobe, should be suspected if vision is affected early (homonymous hemi- anopsia, sometimes preceded by visual hallucinations, such as flashes of light, seeing objects upside down, etc.). Tumors in the temporo- sphenoidal lobe give rise to deafness, loss of taste and smell, and the convulsions which occur often are preceded by a sensory aura. Tumors at the base of the brain are particularly characterized by paralysis of the difi'erent cranial nerves, as well as by hemiplegia, hemianesthesia, etc. Tumors of the hypophysis cerebri may produce symptoms of hyperpituitarism (gigantism in infants, acromegaly in adults) or of hypopituitarism (adiposity, with infantilism in children, and loss of sexual characteristics in adults), according as the anterior or posterior portions of the hypophysis are involved; in either case, the general symptoms of brain tumor are present, together with bitemporal hemianopsia from pressure on the optic chiasm. A good skiagrai)h may demonstrate increase in size of the sella turcica. Subtentorial tvviors may be within the cerebellum or may grow from the meninges. The general symptoms occur early, and are constant and severe; and in addition to the cardinal symptoms of brain tumor already mentioned, these subtentorial growths are characterized esjjecially by vertigo, cerebellar ataxia, nystagmus, etc. Most symptoms occur on the same side as the lesion. Of the extracere- bellar tumors those growling in the cerebeUoyontine angle are most frequent; usually they are fibromas, growing from the sheath of the BRAIN TUMOR 585 ci^litli (Tiuiial nerve, and cause persistent tiiniitus aurinni, and d<>af- ness ot" th • same side; while at a later stage they cause paralysis ol' the fifth, sixth, and seventh nerves, and may finally simulate tumors within the cerehellum (Fig. ()25). They are lightly attached by a small pedicle, and usually can be enucleated easily. JntracereheUar iumors are characterized l)y the early development of vertigo, changes in the eye-grounds (sometimes blindness Ix'fore ])a{)illedema). and sensations of motion of self or of surround- ing objects; the head is tilted, usually toward the side of the lesion, and there is staggering gait, with tendency to fall constantly in one direction, often toward the side of the lesion. The ataxia is not increased by shutting the eyes. It is more marked in tumors of the vermis than in those of the hemispheres. Tumors of the yons and medulla are rapidly fatal, are not amenable to operative treatment, and often camiot be distinguished from cere- bellar growths. Treatment. — An untreated brain tumor uniformly leads to death. Purely medical treatment is inefi'ective even in controlling the most distressing symptoms, pain and blindness. Operation, merely by remov- ing the overlying cranium and thus reliev- ing the brain of pressure {decovii^ession) may cause disappearance of all symptoms for an indefinite period, even restoring sight; and in some cases the tumor can be removed, effectually curing the patient. A radical operation, including removal of the tumor, of course, always is to be preferred; but when an unlocalized tumor exists, making its presence known only by the "syndrome of brain tumor," the surgeon should not hesitate to relieve the headache, check the vomiting, and prevent the development of blindness or possibly to restore sight which has failed, by means of the palliative operation. This operation also is employed when a tumor is found which cannot be removed, either because of its situation, its size, or its infiltrating character. A tumor in one of the cerebral hemispheres is exposed by the forma- tion of a bone-flap (the so-called osteoplastic craniotomy, p. 580), the bone being replaced after the removal of the tumor. If no tumor is found, or if it cannot be removed safely, the bone is removed from the flap, thus converting the operation into one of decompression. Indeed, Horsley never replaces the bone-flap even after the tumor has been successfully removed. But where decompression is planned in ach'ance, the subtemporal operation of Cushing is to be preferred Fig. 625. — Tumor in right cerebollo-pontine angle. Age forty-nine years. Symptoms began two or three years ago; worse for last six to eight months, since which time there have developed ataxia, deaf- ness, facial paralysis, and loss of eyesight. (Paralysis of sixth, seventh, eighth nerves, paresis of ninth, and double choked disk.) (Dr. F. W. Sinkler's patient.) Orthopaedic Hospital. 586 sunaERY of the head (p. 590). A tumor beneath the tentorium is exposed by removal of bone from one or both occipital fossa?; and the bone is not replaced. A tumor of the hypophysis grows either toward the brain, or toward the vault of the pharynx; this usually may be determined by skiagraphy. If the tumor appears accessible from within the cranium, it is best approached across the anterior fossa of the skull, by means of a frontal bone-flap, according to Frazier's modification of McArthur's method (1912): a large bone-flap with external base is elevated from the right frontal region, and the supra-orbital margin and roof of the orbit are temporarily resected. The dura covering the frontal lobe is then elevated from the base of the anterior fossa, and is incised directly over the pituitary body. The sella turcica may also be approached by the lateral route, elevating the temporal lobe from the base of the skull after removal of nearly the entire side of the calvaria (Horsley) ; or by the naso-frontal route of Giordano, employed by Schloffer (1907), and von Eiselsberg (1910); or by the m/ra-na^a/ method of Kanavel (1909), employed by Halstead (1910) and by Mixter (1910). In Halstead 's operations a preliminary tracheotomy was done, and the pharynx was tamponed. Raising the upper lip, an incision is made through the mucous membrane of the superior alveolus, and the cartilaginous septum of the nose is divided. The nose is then retracted upward. After the bony septum and turbinates have been excised, the anterior wall of the sphenoidal sinus is exposed at the bottom of the wound. This wall being broken through, the posterior wall is identified. This lies at a distance of from 70 to 83 mm. from the anterior nasal spine, and often is thinned by the growth of the tumor within the sella turcica. As soon as the latter cavity is opened, the tumor tissue, which usually is fluid, is evacuated and the cavity is lightly curetted. The tumor cavity and the entire wound are then packed with iodoform gauze, which emerges through the nostrils; the nose is replaced and retained by a suture or two, and finally the alveolar mucous membrane is sutured. Osteoplastic Craniotomy, or Temporary Resection of the Skull for Brain Tumor. — The strictest aseptic technique is requisite. Hemor- rhage from the scalp may be controlled by an elastic band passed around the occipito-frontal circumference of the head. The "head- high" position lessens venous congestion. A skin-flap is outlined with a narrow base in the temporal region, the flap being so situated as to overlie the supposed site of the tumor. The tissues of the scalp are not separated from the underlying bone, which is cut through in the same lines as the skin incision. Various methods are employed for dividing the bone: Frazier makes a trephine opening at each side of the base of the flap, and cuts the margins of the bone-flap by Cryer's spiral osteotome (1897), which is a side-cutting rotatory fraise, propelled by a dental engine (Fig. 626) ; Gushing drills holes in the bone at the four corners of the bone-flap, and divides the bone along the top and each side of the quadrangular flap by means of the Gigli wire saw (1897), which cuts from within outward (Fig. 627); OSTEOPLASTIC CRANIOTOMY 587 Fig. 626. — Cutting the bone-flap by means of Oyer's spiral osteotome. Fig. 627. — Cutting the bone-flap by means of the Gigli wire saw. (See Fig. 4.S6.) Fig. 628. — Instruments used in making an osteoplastic flap of the skull: 1. Pe Vilbiss's forceps; 2, mosquito hcmostat; 3, ordinary hemostat; 4, Hudson's trephine (see p. 563), with four bits: 5, the perforator; 6, 7, 8, burrs to enlarge the original perforation. (See Fig. 629.) 588 SURGERY OF THE HEAD others use a bone cutting forceps, like a very narrow rongeur, which nips out a channel of bone around the margin of the bone-flap (Fig. 628); some surgeons use a mallet and chisel, or a circular saw run by a dental engine. The easiest way to drill the holes is by means of Hudson's trephine (Fig. ()29). In any case, after the top and two sides of the bone-flap have been cut through, its narrow base (composed of the thin bone of the temporal fossa) is fractured by prying up the bone-flap by two bone elevators (Fig. 614, 3). Bleeding from the diploe is controlled by application of minute slips of muscle tissue (cut from the temporal muscle) or by plugging with Horsley's wax. Archibald uses the original preparation: beeswax, 7 parts; almond oil, 1 part; salicylic acid, 1 part. Hartley preferred this formula: vaselin, 50 parts; paraffin, 50 parts; phenyl, 5 parts. Some surgeons Fig. 629. — Hudson's trephine in use. prefer to do this operation in two stages, replacing the bone-flap and postponing exploration for the tumor until some days later; but unless unexpected difficulty or delay has attended the formation of the bone-flap, it is better to conclude the operation in one sitting.^ The dura, being thus exposed over a wide area, is incised concentric- ally with the bone, leaving a sufficient margin to facilitate closing it again by suture. When the cerebral cortex is exposed, the tumor may be found on its surface; it then usually is lightly attached, and 1 dishing has found that the second stage of such an operation may be con- ducted without the use of any anesthetic, except "primary anesthesia" for suturing the skin-flap at the end of the operation, since the dura and cortex are totally insensitive to gentle manipulation. DFA'OMI'UKSSIVI-: (U'Mh'ATlOX I'OU liUMX TCMOR :).S!) may he (Miiiclcatcd. If no tumor is visible, it is jiistifiahic to explore the suheortical region. It is extremely important to control liemor- riiage from the pial vessels; any bleeding points should be caught in mosquito hemostats (Fig. ()2S) and ligated or sutured with very fine silk. Sometimes it is sufficient to apply mimite slips of muscle tissue. To explore the subcortical region an incision with scalpel is made in lhe middle of a convolution free of vessels, and if an encap- sulated tumor is found it is shelled out by blunt dissection; a cyst should be evacuated and its lining wall removed if this is possible without trauma. A diffusely infiltrating growth should not be removed. I have seen a surgeon scoop out spoonful after spoonful of tissue from one cerebral hemisphere which was pronounced by several distinguished neurologists who were present to be typically gliomatous in appearance; yet microscopical study j)roved the tissue removed to l)e normal cerebral substance, while at autopsy the tumor was found in a totally different part of the brain. Hemorrhage from the brain substance is controlled by extremely gentle irrigation with hot (115° to 120° F.) saline solution, or by light pressure with pledgets of dry absorbent cotton, or the application of muscle tissue. The dural flap is then sutured as accurately as possible ; the bone-flap is replaced, and the skin is sutured tightly with closely set interrupted sutures of silkworm gut, which control all bleeding from the scalp. Never hurry, and use only extremely gentle manipulations in brain surgery. Keep the wound free from blood, and avoid drainage whenever possible. H ^B *^" 3 M^'* ^1 ^■-^y Fig. 630. — Cicatrix of operation by osteoplastic flap, for middle meningeal hemorrhage. Age fourteen years. (Dr. Frazier's case.) Episcopal Ho.spital. Fig. 631. — Hernia cerebri three months after operation for cerebral tumor. (Dr. W. .J. Taylor's case.) Orthopaedic Hospital. Decompressive Operation for Brain Tumor.— As stated already, an osteoplastic craniotomy may be converted into a decompressive operation by removal of bone from the flap, replacing only the tissues 590 SURGERY OF THE HEAD of the scalp. The ckiral flap which has been turned down for the purpose of exploration, is replaced but is not sutured, and the brain bulges into the opening, relieving the intracranial pressure, and is covered only by the tightly sutured scalp. Such a i)rotrusion, known as hernia cerebri, may be very unsightly (Fig. 631), and as the tumor continues to grow the hernia may become immense, and may cause sloughing of the overlying scalp, with secondary infection of the cerebral substance. A better operation, when decompression is planned in advance, is the subtemporal decompressive operation of Gushing: in this a flap of skin is turned down over the temporal fossa, exposing the temporal muscle covered by its aponeurosis; these structures are then divided down to the bone in a straight line parallel to the muscular fibres, from temporal ridge to zygoma; by retracting the muscle a fairly large area of cranium is exposed; this is trephined, and the opening is enlarged by rongeur forceps and the dura is incised around the margin of the skull opening. The muscle and the skin-flap are then sutured, without drainage. The hernia cerebri, which results, protrudes beneath the temporal muscle, which acts as support, rendering the deformity much less conspicuous. Frazier employs a similar decompressive operation on the occipital bone, in cases of inoperable cerebellar tumors. It may be impossible to close the scalp, in some cases of inoperable brain tumor, after de- compression has been accomplished, owing to the protrusion of the hernia cerebri ; but if necessary this may be diminished by elevating the patient's head, or even by lumbar or ventricular puncture. Patients may live for months or years after a decompressive opera- tion, being symptomatically relieved until rapid death results from some incurable complication. Fungus Cerebri should be distinguished from hernia cerebri, mentioned above. The former is an old term which it is convenient to retain to describe granulations ("proud flesh") springing from cerebral substance exposed in a wound, and developing as the result of infection. Fungus cerebri may occur in cases of compound frac- ture, with rupture of the dura and protrusion of brain substance; or in cases of hernia cerebri secondarily infected from sloughing of the overlying scalp. The treatment consists in antiseptic and astrin- gent applications, of which alcohol is the most efi^ective. This grad- ually causes the granulations to shrivel up. If the fungus is cut off with scissors it will soon return unless the infection is controlled and the wound begins to cicatrize and contract. Focal or Jacksonian Epilepsy, named after Hughlings Jackson, who particularly studied the condition in 1873, was referred to at p. 584, as an occasional symptom of brain tumor. It is characterized by convulsive attacks beginning in one muscle or group of muscles, gradually spreading until finally a generalized convulsion ensues. Consciousness may persist until the convulsions become general, or it may not be lost at all. It is thus distinguished from ordinary ("idiopathic") epilepsy, in which the fits are general from the first, FOCAL EPILEPSY 591 and in which unconsciousness ushers in the attack.* Jacksonian epilepsy is believed to be due either to some localized cortical lesion, or, rarely (and then most often in children and women), to some peripheral sensor}' irritation, arising from a painful cicatrix or other lesion such as eye-strain, dental disorders, genital affections, etc. In cases due to cortical lesion the most frequent cause, apart from tumor, is the result of old trauma; this may have been a depressed fracture, or a meningeal hemorrhage producing a meningo-cortical adhesion, a cyst, or a cicatrix. Similar lesions may be the result of intracranial infections, especially in children, in whom focal epilepsy may develop after an attack of meningitis, poliomyelitis, etc. Treatment. — x\s there is no medical cure for these cases, it is per- fectly justifiable to consider what benefits may be gained from surgical intervention if a definite lesion can be located. Nor should the surgeon hesitate to operate for any surgical condition in another part of the body in an epileptic patient merely because occasional fits occur; for it happens occasionally that cure of a lesion not sus- pected of having any causal relation with the epilepsy results in freedom from, or at least in a lessening in frequency of the convulsions. If a meningeal or cortical lesion is suspected, the centre controlling the muscle group first aflfected is exposed by an osteoplastic flap. Depressed bone is removed; adherent dura is excised, and the re- formation of adhesion is prevented by the interposition of Cargile membrane, silver foil, or similar substance. Free transplants of fascia lata have been used with success. Little can be done for lesions in the cerebral substance. The proper centre may be identified by faradization of the cortex. Kocher (1899) believed a decompression operation alone was of benefit. The sooner any operation is done after the development of focal epilepsy, the more apt is it to be cura- tive; and if all head injuries received efficient treatment at the time of the original accident, the number of cases of Jacksonian epilepsy would be much decreased. 1 Advances in knowledge constantly are diminishing the number of cases of true "idiopathic" epilepsy, and it is not impossible that only our ignorance prevents a recognition of an organic lesion in all such cases. CHAPTER XVIII. SURGERY OF THE SPINE. Spina Bifida, or Hydrorrachis.— Under these names are included several forms of congenital malformation oi the spine, due to failure of proper coalescence in the embryonal medullary plates. Myelocele, or Rachischisis, is the most complete form. In this the skin is defi- cient, and there is exposed on the back of the infant, usually in the lumbar region, a dark red area covered by endothelium, which is con- tinuous above and below with the central canal of the spinal cord. The infant often presents other serious malformations, and usually is stillborn or dies within a few days from continual leakage of cerebrospinal fluid, or from infection. Syringomyelocele: Here the central canal of the spinal chord is distended with fluid, the surround- ing chord is compressed and atrophic, and protrudes as a cystic tumor through a defect in the vertebral laminae. The protrusion, which is covered by skin, or membrane, usually occurs to one side, and not in the midline. Moiingomyelocele is by far the commonest of these deformities, occurring in nearly two-thirds of all cases of spina bifida. The cystic protrusion is formed by fluid which collects in the meshes of the arachnoid, and the roots of the spinal nerves are spread out over the walls of the sac. If the sac presents a dimple or furrow on its surface it is probable that the cord itself is adherent. The laminae of one or several vertebrae may be deficient. Meningocele, in which the protrusion involves only the spinal membranes, and never the nerve roots or the cord itself, occurs only in about 8 per cent, of cases. The tumor is small, covered throughout with healthy skin, never presents a dimple or a furrow, and usually is more or less pedunculated, its orifice of communication with the spinal canal being small. In meningomyelocele, on the contrary, the protrusion is large, sessile, and communicates with the spinal canal through a large defect; and while healthy skin may extend upward from its base some distance, the summit of the protrusion usually is covered by membrane which easily becomes inflamed and sloughing is frequent. Paralysis of the parts below the tumor points to a condition of meningomyelocele rather than of pure meningocele. If there is a defect in the bony wall of the vertebral canal, without the protrusion of any of its contents, the condition is known as Spina Bifida Occulta; this usually is accom- panied by hypertrichosis of the region affected. In very rare cases there has been a defect in the anterior portions of the vertebral canal, constituting Spina Bifida Anterior. Symptoms. — Besides the presence of a cystic growth, usually in the lumbar or sacral regions of the spine, it may be possible to ascertain INJURIES OF TllK SI'IXE 693 by j)ali)ati()ii or .skiu|;raphic exaniimitioii that a defect exists in tlie vertebra?. Compression of the spina bifida usually causes increased tension in the cranial fontanelles, and may prcjduce convulsions. Tension of the cyst is increased durinfi; expiration, and when the child is in the npri<;ht position. Treatment. — 1. // tJicre are oilier serious malforiiiatioiis, or extensive parah/sis, no radical treatment should be adopted, as most of these patients will die within the first year under any circumstances. Efforts to avoid infection should be made, by preventing excori- ation of the sac. If such patients survive more than five years, operative treatment, as detailed below, will be proper. 2. // there are no other serious malformaiions and no parali/ses, the treatment to be adopted depends upon the con- dition of the coverings of the spina bifida: when these are healthy, as in most cases of pure meningocele, operation should be postponed until the child is five years of age; when the coverings are thin or membran- ous, the risk from delay is as great as, if not greater than that from early aseptic operation. Imme- diate operation may be required at any time for rupture of the sac, but when a choice is possible, operation during the second or third month of life is to be preferred (Lovett, 1907). Operation usually consists in excision of the sac, preserving healthy skin coverings, and carefully dissecting free adherent nerves, but cutting away those that cannot be preserved, as the\' probablj' are functionless (Carson). The sac walls are then overlapped, as in radical cure of umbilical hernia, and the muscles and skin are sutured in separate layers, and the wound is closed tightly without drainage. The death rate following operation is from 25 to 35 per cent., and hydrocephalus sometimes develops as a result. Reference was made at p. 556 to Heile's employment of drainage of the sac into the peri- toneal cavity by means of subcutaneous silk threads, with coincident cure of a complicating hydrocephalus. Sacro-coccygeal Tumors. — See Chapter IV. 032. — Spina bifida. Age eightceu months. Orthopaedic Hospital. INJURIES OF THE SPINE. Strains. — Strains of the back, affecting the muscular and aponeu- rotic structures, are much more frequent than true sprains affecting the spinal joints. According to the severity of the injury, these patients 38 594 SURGERY OF THE SPIXE are to be treated by rest in bed, or as ambulatory cases, support being provided during the painful stages by adhesive plaster strapping or plaster of Paris jackets. Restoration of function may be aided later by massage. Sprain-fracture. — Sprain-fracture of the transverse processes of the lumbar vertebrae, unilateral, occasionally occurs from muscular action. Tanton (1910) has collected 17 cases of this injury. Skillern (1913) has reported a case of sprain-fracture of a spinous process. Static Lesions of the Lumbar Spine and Spondylolisthesis are discussed in Chapter X\'I. Concussion of the Spinal Cord. — This term has been used to define a condition supposed to be more or less analogous to con- cussion of the brain fp. 569). It implies that there has been injury to the spinal cord without lesion of the vertebral column; and while some hold that the symptoms which follow a supposed injury have no pathological basis for their existence, being merely one form of neurosis, other authorities believe that actual changes in the cord have taken place, and have left more or less irreparable damage. Many of these patients receive their injury in railroad accidents, and the condition which ensues is popularly known as "Railway Spine," or, because of the improvement which usually follows the settlement of a suit for damages, as "Litigation Spine." As a matter of fact it is probable that most of these cases should be considered severe strains or sprains of the back, and the surgical treatment is the same. For the hysterical symptoms which sometimes ensue, the patients should be referred to a neurologist. Hematomyelia. — Hematomyelia, or hemorrhage into the substance of the spinal cord, sometimes occurs from sudden twists or angula- tions of the vertebral column, perhaps from a self-reduced subluxation, without discoverable gross lesion of the spinal column. It is seen oftenest in the lower cervical region (Thorburn, 1S89). and causes paralysis depending upon the extent of the lesion. Usually the lower extremities recover from the paralysis more or less rapidly, though they may remain spastic, while the flaccid paralysis of the upper extremities continues. There is dissociated anesthesia below the level of the lesion: that is, while tactile sensation is preserved, tem- perature and pain sense are diminished or lo-t. Spinal puncture shows nf) blood in the cerebrospmal fluid. Stab Wounds. — Stab wounds, involving the spinal cord are very rare. From unilateral lesion a monoplegia may result. It is best in civil life to explore such wounds, by laminectomy (p. 601), as it may be possible to repair the injury. Fractures and Dislocations of the Spinal Column. — Fracture and dislocation occur as a combined lesion in about (^0 per cent, of cases of injury of the spinal column, while isolated fractures and disloca- tions form each about 20 per cent, of these injuries. The spine is most subject to injury where its mobile and immobile portions meet, that is, in the lower cervical and the dorso-lumbar regions. Pure IXJIRIES OF rilE SPINE 595 dislocations are very rare except in the cervical rej^ion, as the form of the articular processes renders fracture almost a necessary complica- tion in other portions of the vertebral column. Fractures of the laminae or spiiH.us processes usually occur from direct \iolcnce, as in jiuiishot wounds, or in falls from a height directly upon the hack, impiuf^dnj^ on a stone, fence rail, etc. The most common lesion is a crushing fracture of the bodies of one or more vertebra^, attended by forward dislocation of the vertebra next above, the disjunction of the articular j)r()cesses taking place on one or both sides (Fig. b.'33). Such cases generally are caused by sudden hyperflexion, with twist, of the spinal column, as falls from a height on to the feet or the buttocks, crushing injuries from above acting upon the shoulders, or from a dive into shallow water, ^'iolence acting upon the head or neck usually pro- duces a lesion in the lower cervical region, and that acting from Ijelow determines lesions in the dorso-lumbar portion of the spine. ^■l. >^ ^^^^H ^^^^^^^SS^^flH P'lG. t)33.- — Fracture dislocatirm of eleventh and twelfth thoracic vertebrae. From a specimen in the Mutter Museum of the College of Physicians of Philadelphia. Symptoms. — These may be divided into those due to injury of the vertebral column, and those caused by accompanying lesions of the spinal cord. It is said that the cord escapes injury in about one-third of the cases. Symptoms from Injury of the Vertebral Column. — Of these, deformity is of most value. This may consist in a depression at the point of injury, especially when the fracture is from direct violence, the spines and laminae being driven forward; or it may indicate that there is a partial forward dislocation of the vertebra whose spine is depressed. Such a depression is most apt to be found in a dorso-lumbar injury. In some cases there is angular deformity, a well defined kyphos existing 596 SURGERY OF THE SPINE at the point of injury and indicating the collapse of a vertebral body, causing separation of the spinous processes. Rotatory deformity is seen oftenest in the cervical region, in cases of unilateral dislocation: the head is twisted away from the side which is luxated, and this side maj' be unduly prominent; the sterno-mastoid muscle on the uninjured side is more tense than is that on the injured side. Other symptoms of fracture, such as mobility and crepitus, seldom are present; but persistent localized tenderness is very suggestive of vertebral injury, and in the cervical region muscular spasm, producing rigidity of the neck, is a very usual symptom, especially in lesions of the vertebrne without injury of the cord. A good skiagraph may be necessary to assure the diagnosis in obscure cases. Symptoms from Injury of the Spinal Cord. Motor Symptoms. — Motor paralysis is the most striking and one of the most constant symptoms, and involves all the muscles below the seat of the lesion. Usually it follows the injury immediately, and then indi- cates extensive destruction of the cord, as a rule from crush due to displaced l)one (Fig. 634). If the onset of the paralysis is delayed, it probably is the result of hemorrhage either within the cord {hematomyelia) or in the arach- noid spaces. The former has been con- sidered above; in the latter, which is known as hematorrachis, paralysis of motion usually is more marked than is that of sensation, and gradually ex- tends upward, perhaps in the course of a few hours. In all cases the primary paralysis is flaccid, and the patient is free from pain, at least in the early stages. If the paralysis becomes spastic very soon (12 to 24 hours) after the injury, and if the reflexes are present, it usually indicates only partial de- struction of the cord, from contusion, pressure from displaced bone, hematorrachis, etc. Paralysis which first develops some days after a spinal injury usually is due to inflammatory exudation or blood-clot. But lumbar puncture rarely shows blood in the cerebrospinal fluid. In the cervical region, symptoms of cord injury may be obscured at first by those due to cerebral concussion, caused by the same injury. If the lesion is above the fourth cervical segment, causing paralysis of the diaphragm, immediate or rapid death is usual. Symptoms from paralysis of the cervical sympathetic may be present. Char- acteristic attitudes may be assumed owing to unopposed action of intact muscles (Fig. 635). Fig. G34. — CrushiiiK fracture of first lumbar vertebra. Mutter Museum. IXJlh'lIiS OF HIE SI'INE of)^ It" the lesion is below llie .-ecoiid lumbar \ertebra, i)aralysis may be absent or only partial, o\viii<; to the fact that the spinal eord itself does not extend beyond tliis lex'el, and the injury may invohc only some of the branches of the eauda ('(juina. In rare eases onl\' unilateral (homolateral) paralysis may exist; this is much more usual in stab and gunshot wounds than in eases of fraeture-disloeation. At a later date (after a week or ten days) it is very usual for the patient to experience i)ainful spasms in the paralyzed limbs; and as cicatricial chanf:;es in the cord progress the type of paralysis becomes spastic, and contractures develop (Fig. 244). Fig. 635. — Fracture of cervical vertebrae. Characteristic position of arms when the lesion is above the fourth cervical segment. (Thorburn's position.) (See Fig. 6.36.) Episcopal Hospital. Sensory Symptoms. — Sensation is lost over an area corresponding to that of paralysis of motion, and the upper limit of the motor and sensory paraly.sis is sharply defined, thus determining the level of the injury (Fig. 63()). Pain rarely is severe, though a zone of hyperesthesia is not infrequent at the upper border of the anesthetic area. Shooting pains, from irritation of the sensory nerve roots, are more common in partial cord lesions, and often occur when recovery from severer lesions is beginning. Dissociated anesthesia, as already mentioned, is frequent in hematomyelia. Bed-sores, especially over the sacrum and heels, are very prone to develop in cases of spinal injury, being described as due to trophoneu- rotic disturbances. Whatever is the true explanation, the probability of their early development (within two or three days) always should be borne in mind, and preventative measures instituted. Abdominal and Vesical Symptoms, — Owing to the motor paralysis affecting the muscles of the abdominal wall, and perhaps the muscular tunics of the intestines, tympanites develops. If, as is usual, the lesion 598 SURGERY OF THE SPINE N. to sphincte Coccygeal n _iV. to rectus lateralia ^'Ito rectus antic, minor ^AiuistuDiosis Willi hyijorjlassal _ Anastomosis with pnetnnngastric _N. to rectus antic. major. ..N. to mastoid region. ._Great auricular n. -Transverse cervical n. N. to Trapezius, Any. Scap. and Rhomboid. ,Supra-ctavicular n. .Supra-acrumial n. .Phrenic n. N. to levator any. scap. ^V. to rhomboid . — Subscapular n. . _ Subclavicular n. X. to peetoralis major. Circumflex n. ^^Musculo-cutaneou.-i u. Median n. Radial n. _Ulnar n. _laternal cutaneous ». ..Small internal cutaneous i Ilio-hijpocjaxtric n. lUo-inguinat n. Ejcternal cutaneous n Genito-crural n. Anterior crural i Obturator n. Superior gluteal n. -N. to pyriformis .N. to gemellus super. Small sciatic n. S'Jiatic n. Fig. 636. — The relation of the segments of the spinal cord and their nerve roots to the bodies and spines of the vertebrae. (Dejerine et Thomas, Mai. d. 1. Moelle Epinifere, Paris 1902.) INJLIHES OF 'rilK Sl'lSK 599 is above the spinal centres for tlie bladder and rectum (in the second, third, and fourth sacral se<2;ments), there is rHeniion uitit ovcrjloir (.f the urine and feces, as the voluntary impulses from the cerebrum cannot reach the spinal centres, and the sphincters remain tonicaily contracted until overflow occurs. The bladder becomes distended, and only the surplus urine dribbles away; feces accunuilate in the rectiun, and this is emj)tied only by enema, or finally by exhaustion of the sphincter. If, however, what is very rare, the lesion is so low as to damatije these centres themselves, or the nerves between them and the bladder or rectum, then true incontinence of urine and feces occurs, the bladder remaining empty, while the urine and feces are passed in\oluntarily, and more or less continuously. Ci/n- iitis is very hard to prevent, as a consequence of the habitual use of the catheter which is required as long as retention persists. Fnnpisin, occurring soon after the injury, is common, especially in younger patients, and is said to be more frequent in severe and high lesions than in those at a lower level, or those in which there is only partial destruction of the cord. Prognosis. — It long has been a rule of thumb that when the frac- ture is in the cervical spine the patients will live a week, those with fracture of the thoracic spine a month, and those with fracture of the lumbar spine a year; and this may still be considered a fairly accurate prognosis when there is evidence of complete transverse lesion of the cord. But in the cervical region it is not unusual for the cord to escape injury, mainly owing to the large size of the spinal canal. J. and A. Boeckel (1911) have collected 36 such cases. In injuries of the thoracic and lumbar regions, life may be preserved indefinitely if such complications as bed-sores, cystitis, and pyoneph- rosis can be prevented; and if the cord is not totally destroyed, careful nursing may enable a certain amount of power to be regained. Treatment. — No hesitancy should be felt in reducing any deformity present, especially in the cervical region; but this should be done judiciously, and with a clear idea of the mechanism of the injury. The fact that one or more such attempts have resulted in the patient's immediate death, demonstrated nothing, as pointed out by Mal- gaigne, as long ago as 1843, but that the attempts were unskilfully made by an incompetent person. In studying nearly 400 cases of spinal injury, John Ashhurst, Jr. (1867) found that in the treatment of dislocations in the cervical region the mortality had been nearl}^ four times greater when no attempts were made to reduce the deformity, than when this was undertaken by extension, rotation, etc. Walton (1892) systematized the reduction of these injuries, omitting attempts at extension (longitudinal traction), which he demonstrated to be useless, and employing only " retro-lateral flexion and rotation," in the unilateral cervical dislocations, which are the most frequent cases. Reduction is accomplished, after etherizing the patient, in this manner: the surgeon stands behind the seated patient, and grasps the head between his hands; the head is then 600 SURGERY OP THE SPINE tilted backward, and flexed slightly away from the dislocated side, so as to release the dislocated articular process from the interver- tebral foramen of the vertebra next below, where it is usually caught. The head is then rotated so as to carry the dislocated side ))ackward. Reduction of the deformity may be attended by an audible or pal- pable click. The patient should remain in bed, with the head and neck immobilized by plaster of Paris dressings, or by sand-bags with weight extension (as in cervical Pott's disease, p. 609) for a couple of weeks, and some retentive appliance should be worn for some weeks longer, or until the ruptured ligaments have had a chance to heal. Bilateral cervical dislocations may be reduced by the same method, applied to each side separately. The deformity from frac- ture, seldom present except in the thoracic and lumbar regions, usually is best corrected by hyperextension of the spine. In every case with cord injury, the patient should be kept on a water bed, with head and foot extension, as in tuberculosis of the spine (p. 609) ; and the utmost care should be taken to prevent the development of bed-sores (p. 62). The bladder should be drained by an inlying catheter, if there is retention of urine; and the bowels generally have to be moved by enemas. In most cases nothing further can be done than to keep the patient comfortable by careful nursing. If life is preserved, efforts must be made to maintain the nutrition of the paralyzed parts by massage; the development of deformities from contractures (Fig. 244) should be guarded against, though these may be corrected later by tenotomies; and eventually such orthopedic apparatus as is indicated should be provided, as in this way patients otherwise nearly helpless may regain some power of locomotion. The Quesiion of Operation. — In cases where, after the first few days, it seems that the cord has not been completely destroyed — as evi- denced by persistence of reflexes, early development of spasticity, with shooting pains, spasmodic contractions, etc. — it is justifiable to expose the injured cord by laminectomy, in the hope that evacuation of blood-clot (almost always extradural) or even the removal of counter-pressure on the cord by the laminae and arches, may accel- erate the cure. But it is in just such cases as these that a fair amount of improvement may occur without operation; yet as this cannot be certain beforehand, and as operation in such carefully selected cases does not increase the mortality, I think it should be employed. Very early operation (on the day of injury, if possible), is proper in all cases where the spines and laminae have been driven inward against the cord by direct violence; since in such cases it is reasonably' sure that the displaced fragments continue to compress the cord, or that hema- torachis will develop later. The same is true of gunshot wounds of the vertebral column, in civil life, involving the arches; these should be treated by laminectomy and removal of displaced fragments, whether or not there are cord symptoms. In other cases, with symptoms of complete transverse lesion, in most of which the osseous lesion is collapse of the vertebral bodies, it INJURIES OF THE SI'INE cm is oxtreiiH'ly j)r(tl);il)l(' tliiit the cord luis liccii cruslicd ])\ tlic (iisphiccd hoiu' at the tinic of tlii' accident, hut that there is no coiitimiiii^ j)res- siire from the hone; and even did such pressure exist, it is extremely iniprohahle that relief of the cord from it would in any way promote recovery of function. It is artjued hy some that ah fractures of the vertehrie should l)e treated by immediate operation, as in the case of fractures of tlie cranium. But the cases are not similar; for in fractures of the cranium we Fig. 646. — Early psoas contraction from left iliac abscess. Age eleven years. Pott's disease, for four years. Abscess for eight months. Orthopaedic Hospital. side of the femoral vessels (Fig. 644). Usually such an abscess may be detected w^hile still in the iliac fossa, when it is known as iliac abscess. Sometimes, instead of entering the psoas sheath, the pus passes beneath the external arcuate ligament, and points in the lumbar region {lum- bar abscess), simulating a perinephric abscess (Fig. ()45). A^ery occa- sionally an abscess may leave the pelvis through the sacro-sciatic notch and point in the buttock {gluteal abscess); and an ischio-rectal abscess sometimes may be traced to the spine. Diagnosis of Abscess. — ^These various forms of abscess should be watched for. Their de^Tlopment may account for contractures (especially of the psoas muscle), for an apparently inexplicable exacer- bation of symptoms (pain, fever, disability), and very occasionally (when the abscess ruptures into the spinal canal) for suddenly devel- oped paraplegia or meningitis. Psoas contraction is best demonstrated by placing the child on its back, with its lower limbs hanging over the end of the table: the normal 608 SURGERY OF THE SPIXE limb will drop below the horizontal, while one with psoas contraction will remain flexed at the hip, in spite of compensatory lordosis (Fig. 646). Or, with the child prone, the hip-joints may be tested for hyper- extension, as in the examination for coxalgia (p. -idO). There is little difficulty in distinguishing between coxalgia and psoas contraction secondary to Pott's disease; in the former, the motions of the hip are limited in all directions, not only in extension; and there are no evi- dences of spinal disease. An iliac abscess usually is palpable, a dis- tinct fulness, which is absent on the normal side, being present along the course of the psoas muscle. Intraperitoneal abscesses, as from appendicitis, are of much more acute development, with symptoms of peritonitis, and are attended by leukocytosis. Fig. 647. — Pott's disease ^"ilh extreme angulation, but not SufScient to cause para- plegia. Note that there are present the spines of fourteen vetebrse — bodies of only seven ; in other words, seven bodies have been destroyed. From a specimen in the Miitter Museum of the College of Physicians of Philadelphia. Paraplegia from Pott's disease, is the effect of a "transverse myeli- tis," or degeneration of the spinal cord from pressure. This pressure very seldom is caused by bony deformity from extreme angulation (Fig. 647). Almost always the pressure is due to tuberculous granu- lation tissue, usually extradural in situation. Rarely the rupture of a cold abscess into the spinal canal will cause paraplegia, which in these circumstances generally appears suddenly. In most cases the para- plegia is slow in onset, the patients first becoming spastic, and only gradually losing the power of locomotion. Sensation is not often lost entirely, even when motion is entirely aboji.shed; but h\'pesthesia and paresthesia are frequent. Complete flaccid paralysis is rare. Inter- ference with the functions of the bladder and rectum occurs as in fracture dislocations of the spine. Meningitis. — See p. 579. TlliEliVLLOSlS OF THE Sl'lNE 609 Prognosis. The disease is seldom cured; in adults scarcely ever. It may he arrested in childhood, and many u "hump-hack," even with marked tieformity, is enahled to lead for years an active and useful life. But recurrence of symptoms always is to he feared. Very few patients die as a direct result of the disease, and then mostly from complications, such as tul)erculous menin<;;itis or amyloid defeneration of the ^■iscera; hut hefore the disease hecomes latent ])rol)ahly one patient out of every three affected will die from intercurrent maladies which would have been survived, had not the viscera, particularly the heart and lungs, been so distorted by the spinal deformity. Neither an unopened abscess nor the onset of paraplegia seems to render the prognosis more grave; but the rupture of an abscess, w'ith the secondary infection which this entails, opens a door, as Calot says, through which death soon enters. Fig. 648. — Extension from head and Ijoth feet for Pott's disease. Orthopaedic Hospital. Treatment. — To secure rest for the diseased spine recumbent treat- ment is almost indispensable, and in the acute stages is imperative. This at once removes the superincumbent weight. The use of the Bradford frame (Fig. 497), to which the child is strapped, largely pre- vents motion in the spine, and immobilit}- is further favored by head and foot extension (Fig. 648). Meanwhile, the patient should be kept in the open air, night as well as day whenever possible, and all the general measures useful in surgical tuberculosis should be adopted (p. 82). During recumbency it is especially important to prevent "pointed-toe deformity," which is very apt to develop if the foot is 39 610 SURGERY OF THE SPINE unsupported and kept constantly in the equinus position by the weight of the bed-clothes. Careful trained nursing is indispensable. A nurse trained especially in this work is desirable whenever her services can be obtained. If recumbent treatment can be instituted before deformity develops, it may be possible to secure arrest of the disease, and to prevent the occurrence of subsequent deformity. As in the case of tuberculous coxitis, the only patients I have seen whom I could consider really cured of the disease, without impairment of function, were those in whom such treatment was adopted before the diagnosis was entirely certain. When once a kyphos has developed it is very seldom that surgery can do anything better than to prevent increase of deformity. Whitman prefers to treat early cases on a frame which keeps the spine hyperextended ; this treatment is not applicable when fixed deformity already exists, and is open to the theoretical objection that it prevents collapse of the diseased vertebral bodies and thus hinders ankylosis, which should be encouraged, as the only chance of permanent cure. At one time Calot (1896) was an advocate of forcible correction of any existing deformity, the patient being anesthetized ; but a thorough trial of the method has caused it to be abandoned not only by other surgeons but by Calot himself. It was found that the death rate was markedly in- creased (shock, traumatic pneu- monia, miliary tuberculosis, spinal meningitis, etc.), and that the ultimate cure of the disease was not accelerated nor the final deformity diminished. When all symptoms of the disease have been absent for two or three months at least, ambulatory treat- ment may be tried with great caution, and never without efficient support to the spine. The plaster jacket, when properly applied, is a most efficient support. It may be applied with the patient re- cumbent, or suspended by the head and shoulders, the heels just clearing the floor (Fig. 649). For most cases of thoracic and lumbar disease I think the prone position is preferable (Fig. 650) : the child lies on a sling attached at both ends, by a bar and ratchet, to a Bradford frame; the sling is left just lax enough to allow slight hyperextension of the spine, and is included in the plaster bandages, being slipped out after the plaster jacket has dried. With a seamless undershirt next the skin, and all bony promi- nences (pelvis, kyphos, axillse) well padded with saddler's felt, such a Fig. 649. — Application of plaster jacket with patient suspended. Orthopaedic Hos- pital. rUHERCCLOSlS or TIIK SPINE Oil jacket may he worn for several moiitlis in comfort. The sur^n;on slionld smell the Cast all over every few weeks, and thus may detect very earlv anv evidence of excoriation. As an additional ^Miard aj;ainst Fig. GoO.- -Position for applying plaster jacket in Pott's disease. Hospital. OrthopiL'dic such an occurrence, "scratchers" may be inserted next the skin before the jacket is applied : these are long pieces of bandage, with their pro- truding ends sewed to each other, and are to be drawn up and down every day or so, to keep the skin in good condition. For high dorsal (above the eighth thoracic vertebra) or cervical disease the head and neck must be im- mobilized also; and in such cases it is more convenient to apply the jacket with the patient suspended. The front of the cast should be cut away to diminish its weight (Fig. 651). Braces. — These depend more on fix- ation (limitation of movement) _ than on support in the sense of relief of weight-bearing. Davis's brace (Fig. 652) (1898) takes a fixed point of sup- port at the pelvis (between iliac crests and great trochanters) by means of a malleable steel band; over the iliac crests pass well-padded straps, attached behind and in front to the pelvic band, which eft'ectually prevent the brace from sliding downward. Up from the pelvic band on each side of the spine runs a light steel bar, connecting through a cross-bar above with crutch pieces under the axillae; these are sup- ported below by steels attached to the pelvic band in the mid-axillary line. Nothing passes over the shoulders, as the object is not to hang the apparatus from the shoulders, but to support the weakened spine from below. The brace is thus fixed below at the pehis and abo^'e at the Fig. 651. — The plaster of Paris jacket for upper dorsal disease. The jacket is trimmed away above and below, and the large abdominal window is cut to allow of free breathing and feeding. (Cheyne and Burghard.) 612 SURGERY OF THE SPINE shoulders, and presses forward on the transverse processes at the level of the kyphos, thus tending to hyperextend the spine and relie^•e pressure on the bodies of the vertebrae. If the lesion is above the eighth thoracic vertebra it usually is desirable to support the head also, by an attachment to the spinal uprights. When ambulatory treatment is first com- menced, the apparatus should be worn at night as well as during the day, of course being removed once daily for bathing; but the patient never should he in any other than the recumbent yosiiion except ivhen the sjnnal support is in place. It should be taken off only after he lies down and should be put on again before he even sits up. Some support of this kind scarcely ever can be dispensed with; when it is abandoned symptoms nearly invari- ably return. This has been demon- strated to be a fact in so many cases that it is almost foolhardy for a sur- geon to tell a patient to throw away his braces and go without support. Only after many long months of free- dom from symptoms is it desirable to dispense with the crutch pieces of the apparatus, the brace then con- sisting merely of a pelvic band, spinal uprights, and shoulder-straps. Such an apparatus gives practically no support, but prevents dangerous degrees of movement in the spine. Operative fixation of the spine, in recent cases of Pott's disease, has been tj employed by several surgeons. Lange inserts two steel bars, one on each side of the spinous processes, and fastens them above and below to the transverse processes of healthy vertebrae. Albee splits the spinous processes of vertebrae over the seat of disease and of two more above and below, and inserts in the cleft a sliver chiselled off the patient's tibia; when this grows fast firm ankylosis is secured. Hibbs chisels partly through the spinous processes at their base, turns each one down until it comes into contact wdth the base of the spinous process next below^ and thus covers the diseased region of the spine with a solid bridge of bone. Of these various measures I believe Albee's operation of bone transplantation is the best. I have employed it in seven cases, and apart from one death from pneumonia, all the patients have shown marked improvement; but in one (Fig. 653) the Fig. (i,jlj. -liracc lui rervical or high dorsal Pott's disease. Ortho psedic Hospital. TUBERCULOSIS OF THE Sl'INE 013 transplant later hecanio loosened at its lower extremity, and a new kyplios developed. Treatment of Abscess. — -The general prineiples wliieh should guide surgeons in the treatment of tuhereulous abseesses and sinuses have been diseussed in Chapter XV. If reeumbeney and immobility do not cause retrogression of the abscess, and still more so if it continues to enlarge, it should be incised through healthy overlying tissues, should be carefully evacuated, its cavity should be thoroughly wiped out with iodoform gauze, and the incision should be tightly closed by several layers of sutures (see Fig. 045). A retropharyngeal abscess Fig. 653. — Bone transplant in lumbar spine. Epi.scopal Hospital. requires early evacuation, to prevent rupture into the pharynx or secondary infection from the same source. In adults local anesthesia is sufficient. An incision is made, in the lines of the skin, at the pos- terior border of the sterno-mastoid muscle, and this is defined and drawn forward; usually the bulging abscess is found just beneath the muscle, and may be opened by Hilton's method (p. 51). The abscess wall, the muscle, the platysma, and the skin, should be sutured if possible in separate layers. An abscess in the posterior mediastinum rarely requires drainage ; it is exposed by excision of the heads and necks of the ribs, with the corresponding transverse processes of the diseased 614 SURGERY OF THE SPINE vertebra? (costo-transversectomy) . Injury to the intercostal nerves, and especially to the i)leura should be avoided. An iliac abscess may be opened by a small McBurney muscle-splitting incision as in appen- dicitis (p. 820), without fear of invading the peritoneum if the incision is made close to the ilium and the dissection keeps close to iliac fossa. After evacuation, and thorough wiping of the abscess walls with iodoform gauze, the wall of the abscess ca\'ity and the structures of the abdominal wall are sutured in layers. A psoas abscess does not admit of such secure closure, after evacuation just below Poupart's ligament; but the abscess wall, the fascia lata, and the skin usually can be closed in separate layers. A lumbar abscess is approached as in operations on the kidney, and usually the abscess wall, the lumbar fascia, and the skin, can be sutured separately. If the abscess is giving no symptoms, does not tend to enlarge, and is not so near the skin as to make probable the occurrence of secondary infection from skin cocci, it should be left alone, and the patient should be treated as if it did not exist. Constant watch, however, should be kept, and proper treatment promptly adopted whenever required. It seems unnecessary to add anything as to the treatment of sinuses to what was said in Chapter XV. Treatment of Contractures. — Often recumbent treatment, with weight extension applied first in the axis of the deformity, will allow contractures gradually to be overcome. Occasionally tenotomies are required (adductors, psoas, rectus femoris, tensor fasciae femoris, ham- strings, tendo Achillis, etc.). But in many cases which have been neglected, sinuses exist, with secondary infection; amyloid degener- ation of the viscera is present; and nothing remains but to alleviate the patient's miserable state until death ends the scene (Fig. 243). Treatmetit of Paraplegia. — In almost every case in childhood recum- bency will cause disappearance of paraplegia in the course of six months or a year. In such cases, then, it is only after the failure of such treatment that the question of operation need be raised. In adults, also, recumbency in most cases will cause return of power within that time. If after eight months or a 3'ear of recumbent treat- ment in adults no improvement is noticed and spasticity still persists, I think laminectomy (p. 601) should be done, and the tuberculous granulation tissue excised; the dura should not be opened, as tuber- culous meningitis probably would ensue; and it is quite useless, and perhaps not always harmless, to curette away carious bone from the vertebral bodies. Only when the paraplegia is of suddeji onset do I think laminectomy should be undertaken as an early operation. In ordinary cases the symptoms come on very gradually, and the ultimate complete or nearly complete recovery, even after many months of complete abolition of the motor functions, is due to this very feature, as the cord gradually accustoms itself to the condition of pressure. But when the onset is sudden or very rapid (complete paraplegia developing in a few days in a patient previously not even spastic), the cord has not the time to so accustom itself, and there is INFECTIOUS SPOXDYLITIS (US ^Tcat (lan'ond recognizing this fact ancl acknowledging the possibility that proper treatment by a skilled dermatologist might i)revent or at least delay the (le\'clopment of epithelioma, neither pathologist nor clinician can go. Before there is any suspicion of malignancy, careful treatment of the skin should be adopted. The face should be well steamed over a bucket of hot water, at least once daily; after thoroughly' drying, a little salicylic acid ointment (10 grains to the ounce) should be rubbed into the seborrheic patches. Sometimes green soap (Tinctura Saponis \'iridis, U. S. P.) should be used instead of ordinary toilet soap. D. W. Mont- gomery, who has studied these cases most carefully, wipes ott' the skin with glacial acetic acid, and in rebellious cases uses trichloracetic SURdEh')' OF rill-: CIIKI'JKS 023 acid, alter turcttiiiK the le.su)ii; then the .f-rays are eiiiph)\e(L He l)()in'ts out that wlieii the cheeks or other portions of the face are widelv alVected radical excision is not to he considered even if the iy¥—)^-^t^r- Y ^^ yj^k^^Y Y Y Fig. 662. — Typical plastic operations. epithehomatons nature of the lesions is recognized; and any flaps used to repair defects left hy partial excision will themselves be the seat of these precancerous growths, and will in time develop mto epithelioma, causing an apparent local recurrence. If only one or (i24 SURGERY OF THE FACE, MOUTH, AND NECK two patches exist, they should be treated by excision, as in fully developed epithelioma. Superficial Epithelioma or Rodent Ulcer occurs more often on the cheeks or forehead than any other part of the face, especially near the ala nasi, on the lower eyelid, or near the angle of the mouth. Some authorities claim that it owes its comparatively benign character to the poverty of these areas in lymphatic vessels. Its pathology and clinical course have been discussed in connection with tumors, (p. 123). The question of diagnosis is important. It must be distinguished from deep-seated epithelioma, lupus, and syphilis. Deep-seated epithelioma rarely occurs on the face except on the lower lip; it may develop from a seborrheic patch, but it is much more rapid in growth than the superficial form (months instead of years), and invades the regional lymph nodes. Lupus usually affects young adult patients of scrofulous diathesis; it is very rare in those past middle life in whom epithelioma is common; it almost always presents evi- dence of having healed at some part, which is rarely the case in epithe- lioma; and the typical apple-jelly nodules usually can be discovered around the periphery of the ulcerated areas (p. 263). The facial lesions of syphilis, especially ulcerated gummas, sometimes are mistaken for epithelioma; but the previous history of the patient, the presence of syphilitic lesions or their traces elsewhere in the body, the cir- cinate or reniform shape of the ulcers, their greater depth and much more rapid extension, as well as the result of antisyphilitic remedies, and the presence of the Wasserman reaction, will render the correct diagnosis evident. It should not be forgotten, however, that malig- nant changes may develop in old syphilitic or lupous ulcers. Treatment. — Treatment of rodent ulcer consists in excision of the entire thickness of the cheek down to mucous membrane or bone. The wound is then repaired by sliding flap as indicated in the accom- panying diagrams (Fig. 662), or by Wolfe grafts. When it has been necessary to sacrifice the mucosa also, the defect in the cheek may be repaired by taking a pedicled flap from the neck and adjusting it in place with its skin surface toward the cavity of the mouth. The operation of repairing a defect in the cheek is known as meloplasty. SURGERY OF THE SALIVARY GLANDS. Infectious Parotitis, called also symptomatic parotitis, and parotid bubo, is an acute bacterial infection of the parotid gland occurring in the course of some general infection (typhoid fever, scarlatina, pyemia, etc.). In rare cases the submaxillary or sublingual glands are similarly affected. In contradistinction to epidemic parotitis (mumps), only one parotid usually is affected, and suppuration is frequent. Cases of this nature may also follow abdominal or other operations, but rarely, if ever, unless general anesthesia has been induced. In all such instances, as in typhoid fever and other wasting diseases, there is abundant opportunity for a direct ascending infection from the SURGERY OF TIJK SALIVARY GLANDS 02.") moiitli alonfj; vStcnson's duct; and while infection through tlic hlood- streani cannot he deniech it prohahly is rare. In the suhstance oF the parotid ghuid, l)et\veen its h)hules, there are numerous minute lymph nodes; and it is possible that some cases classed as parotitis really are instances of lymphadenitis of these nodes. Prophylaxis is important, and consists in measures to promote cleanliness of the mouth and prevent drying of the nuicosa around the orifice of the })ar()tid duct. Mechanical injury of the glands should he avoided during anesthe- tization. Treatment. Local api)lications (ice bag, painting with iodin, mouth washes) may be useful before suppuration occurs. This should be treated i)romptly by incision parallel with the branches of the facial nerve. A probe is then inserted, and an endeavor made to secure drainage of all pockets of pus through the one opening; but owing to the dense fibrous stroma of the gland each suppurating lol)ule may ha\e to !)c incised separately. Tuberculosis sometimes attacks the parotid lymph nodes, but very rarel}^ affects the glaiid itself. Excision of these nodes is difficult without injuring the facial nerve. Tumors of the Parotid. — The peculiarity of parotid tumors is that they usually are of the "mixed" variety (p. 106). This may be due to the situation of the parotid in the region of the first branchial cleft of fetal life. These tumors are very apt to contain cartilage, with areas of myxomatous degeneration; rareh' cysts may form. They occur in young adults, and grow with extreme slowness; often no change is appreciable from year to year (Fig. 063). At first they are fairly well encapsulated, but owing to the def^p relations of portions of the parotid gland, they appear to be fixed at an early stage of deAclopment. Though the tumor may grow to an immense size, the facial nerve seldom is affected; but the lobe of the ear becomes dis- placed, outward and upward. If rapid growth develops, as it usually does in time, malignancy should be suspected (Fig. 664). In very advanced cases, secondary enlargement of the cerA'ical lymph nodes may occur. Similar growths may occur in the submaxillary salivary f/hnids, but are much rarer, and seldom are distinctly cartilaginous. Treatment. — If the patient is seen before the tumor is large, and before rapid growth has commenced, it often is possible to enucleate the growth from the substance of the parotid without injury to the facial nerve or Stenson's duct. Operation should be urged before the tumor grows very large. The incision should be made parallel with the branches of the facial nerve, nearly as high as the zygoma, and the knife should pass at once to the tumor, with no dissection of the superficial structures, as this is apt to injure the facial nerve. The growth is then enucleated, and the wound closed by buried and super- ficial sutures. In malignant cases wide-sweeping excision must be practised if any operation is undertaken, but an attempt should be made to preserve the facial nerve by exposing its main trunk before it enters the tumor. Preliminary ligation of the external carotid 40 626 SURGERY OF THE FACE, MOCTII, AXD XECK artery often is advantageous. Blunt dissection should be avoided. The parts should be freely exposed, and nothing should be cut that cannot be seen. The operation is tedious, difficult, and dangerous. If the tumor extends far into the retro-maxillary fossa and appears densely adherent there, as ascertained by preliminary examination through the mouth, usually no operation should be done. (See also remarks on Excision (jf Tumors, p. 131). HIPH ^B ^^^^H ^^^^Bjj! --.... ^O- __^^^^^M ^^^ ' >MH Fig. 663.— Mixed tumor of parotid, age forty-two years; duration twenty-two years. Verj- slow growth. Episcopal Hospital. Fig. 664. — Mixed tumor of parotid (sarcomatous;; twenty-one years' dura- tion. Weight of tumor two pounds. Re- moved by the late Prof. Ashhurst, 1896. University Hospital. Mikulicz's Disease (1892) is a rare affection characterizerl by pain- less, slowly (le\'eloping, chronic, symmetrical enlargement of the parotid and lachrymal glands; sometimes the sul)maxillary and sub- lingual glands are involved also. In some cases there is general lym- phatic involvement and enlargement of the spleen. There may be fever. If such constitutional remedies as arsenic and iodide of potash are ineffectual, extirpation may be justifiable for cosmetic reasons, or to relieve pressure on neighboring structures. The cause of the disease is unknown. Salivary Fistula. — This usually arises in the parotid gland, especi- ally in its main duct, as the result of injury (operative or accidental) or suppuration. The secretion discharges on the cheek which is kept constantly moist, especially while food is being masticated. The skin may become very much irritated. The mouth feels dry. The patient is rendered both conspicuous and miserable. Treatment. — If the orifice is in front of the masseter muscle the fistula is not so difficult to cure. A cannula may be passed from the mucous surface of the cheek through the fistula on to the cheek where it makes two punctures, about one centimeter apart; a fine wire (of silver, iron, or bronze-aluminum) is then passed through these two SUlUiEUY OF Tlll<: SALIVARY (iLA.\US ivi: artificially iiKuk- niiicous orifices (Fi^'. ()(').")), and is tied on the mucous surface (Fiji;. (KiO). The edges of the cutaneous orifice are then fr<'sh- ened, and it is closed by suture. The parotid secretions then find their \v;i\ aiong the wire to the mouth, and. by the time the wire cuts out and establishes an internal opening the cutaneous orifice has healed. If the fistula is situated over the masseter muscle, at- tempts should be made to con- struct a chaimel forward in the cheek to its anterior edge, either ^ , ^ ^^^-==^ Mucosa Sa/ira/y duc^ Fiii. 005. — Operation for salivary fistula: both ends of a wire are conducted to the mucous surface of the cheek through punc- ture made by a cannula. C'utaneo/js opc/ii//^ off/s/ula -Skin Fig. 666. — Operation for .salivary fis- tula: the wire is tied on the mucous sur- face. by establishing a seton, as in the method just descrif)ed, or by a formal i)lastic operation. Occasionally partial excision of the parotid gland will be necessary to cause cessation of discharge. If no infection is i)resent, simple ligation of the main (fuct on the central side of the fistula may result in atrophy of the gland. Sialo-lithiasis or Salivary Calculus is not a very uncommon condition. In 1908 Bendixen referred to 216 cases. The calculous formation is due to bacterial action on the secretion of the glands, as in the pathogenesis of biliary calculi. The calculus usually obstructs the excretory duct, causing secondary enlargement of the glands, with mild inflammatory symptoms. Occasionall\- recurrent attacks of colic occur. The affection is much more common in the submaxillary than in either the parotid or sublingual gland. Often the calcu- lus is palpable in the floor of the mouth, just beneath the mucosa. Treatment consists in removal of the stone by incision in the floor of the mouth; if the calculus is in the body of the gland, and especially if there is suppuration or a cutaneous fistula, it is better to excise the entire gland, by an incision beneath the mandible. Chronic Inflammation may affect the submaxillary and sublingual salivary glands. The affection may simulate a neoplasm in its gradual Fig. 667. — Chronic inflammation of submaxillary and sublingual sali- vary glands and of submaxillary lymph nodes. Episcopal Hospital. C)28 SURGERY OF THE FACE, MOUTH, AND NECK onset and indolent course. Usually the glands are found to contain minute abscesses, and there is increase in the connective tissue. Extir- pation is the proper treatment (Fig. 667). SURGERY OF THE EAR. Foreign Bodies. — It is necessary first to ascertain whether or not the foreign body still is present. In children the history is not always very clear, and much harm may be done by incautious exploration. If a probe or forceps is pushed blindly along the canal, the foreign body may be driven further in. Under good ilhmiination from a head-mirror, and by drawing the pinna upward and backward to straighten the external auditory canal, the surgeon will be able to detect the presence of a foreign body (Fig. 668). In children the use of an ear speculum seldom is necessary, but where the canal is hairy, as in many adults, this is indispensable. In most cases persistent syringing with warm sterile saline solution or weak antiseptic will be successful in remov- ing the foreign body; but if this is a pea or bean the soaking may cause it to swell up and thus render its removal more difficult. For such bodies, therefore, and for all others where syringing has failed, delicate forceps or scoop should be employed. The same methods should be employed in cases of impacted cerumen. Sy^m^ Fig. 668. — Examination of external auditory canal bj- light reflected from a head-mirror. Furuncle. — Furuncle of the auditory canal is an exceedingly painful condition which requires prompt incision. Even though the sharpest knife is used, and the incision made with great delicacy, the pain is excruciating, but if the auriculo-temporal nerve, just in front of the tragus, is infiltrated with a few drops of a 2 per cent, novocain solution complete anesthesia is secured (Skillern, 1913). After opening, the crater of the furuncle should be touched with a drop of tincture of SURGERY or Till' EAR 629 Fig. 669. — Proper incision to evacuate an othematoma. iodiii or i)iir(' carholic acid; and a small plcdj^'ot of cotton slionld l)e iiitrodnccd, and an ast'ptic dr('ssin<^ then l)an(laji;ed to the auricle. Hematoma Auris or Othematoma nsually is the result of a blow. It i.s not unconunon in patients in insane asylums, who can ^ive no account of its api)earance; and on this account it has been thought to have some occult connection with un- soundness of mind. If it ever develops spontaneously, it probably is to be attrib- uted to arterio-sclerotic changes. The eH'used blood separates the skin from the cartilage, usually over the pinna; and unless proper treatment is instituted the auricle will become conspicuously deformed from organization and cicatrization of the thrombus. Tlie blood may be aspirated by a hypodermic needle in very recent cases; but usually the blood is semi-clotted, and an incision is necessary. This should be made along the helix (Fig. GG9), and after the blood is evacuated the skin should be reapplied very carefully to the underlying cartilage and should lie held against it by accurate adjustment of small pads and a firm l)and- age. Unless this coaptation is very firm and exact, re-accumulation of blood will occur. After a few days massage should be employed. Prominence of the Auricle, either congenital or acquired, may be remedied by suitable plastic operation. In the usual congenital form the pinna hangs down like a hood, and the condition is named " lop- ear." Generally it is sufficient to remove an ellipse of skin from the posterior surface of the auricle and adjoining scalp, and then to suture the ear against the head and keep it in place by a firm bandage. Some such support should be worn for several weeks. Occasionally it is necessary to excise some of the cartilage of the auricle also. Supernumerary Auricles are not very rare. Excision is the proper treatment. Otitis Media. — The middle ear is a mucous-lined cavity, draining into the pharynx through a long and narrow channel, the Eustachian tube. Infection usually ascends from the pharynx, which often is septic, especially if adenoids are present. Occlusion of the Eustachian tube or of either of its orifices renders the middle ear a closed chamber where microbes are prone to multiply and increase in virulence. The middle ear in these respects resembles the \ermiform appendix. In cases of middle-ear disease or its complications, the services of an otologist are desirable; but as these cannot always be obtained in emergency, the general surgeon may be called upon to treat the acute stages of such lesions. Only emergency treatment, therefore, is considered in this work. Catarrhal inflammation of the middle ear frequently develops after an attack of measles, pneumonia, scarlatina, or other infectious 030 SURGERY OF THE FACE, MOUTH, AND NECK flisease. It is accoinpaiiicHl by ear-ache, sli<,flit deafness, a sense of fulness in the ear, sH' instillation into the external auditory canal of a few drops of hot water. This is quite efficient as hot laudanum or other drug. It is the heat rather than the drug that is effective. If there is evidence of accumulation of fluid within the tympanic cavity, especially if there is any bulging of the membrane, this should be incised (myringotomy) : after suitable clean.s- ing of the canal by dilute hydrogen peroxide and aseptic syringing, the incision is macle in a cur^•ed line around the entire posterior cir- cumference of the drum membrane, thus forming a flap, which allows much more free and prolonged drainage than a mere puncture. The point of the knife should not do more than penetrate the membrane, as the tympanic cavity may be very shallow\ The ear is drained by a small strip of gauze extending just as far as the drum membrane; this should be renewed as often as it becomes soaked with discharge — several times an hour if necessary. Several times daily, not oftener than every two or three hours, the canal should be irrigated gently with a weak antiseptic solution. Heat to the mastoid will be grateful, and sedatives may be requisite to allay the pain. The patient must be confined to bed for several days. The nasopharynx, whence the infection usually has come, should receive appropriate treatment. Acute Mastoiditis. — Invasion of the mastoid cells, by extension of infiammation from the middle ear through the aditus and the antrum, occurs in many cases of acute purulent otitis media. Prom])t treatment of the' middle-ear disease by myringotomx' will permit SlfRGERY OF THE EAR (VM rec()\('r>' in many cases witliDUt pennaiiciit daiiiaf^c to the aiitriim or mastoid. It' the discharjfo of j)us jxTsists Inii^f, and is profuse, in s|)ite of pro|)er conservative treatment of the middle ear, it usually indicates that there is involvement of the mastoid cells. This is a chronic condition, however, and does not concern us here. Not infre- (piently, shortly hefore s\inj)tonis of nriitr mastoiditis a])pear, an ear which had i)cen "running'" for months or years suddenly ceases to discharge. Tlie patient has pain in and l)ehind the ear; there is fever, perha|)s chilliness or an actual chill; lieadache aiui general malaise. The mastoid is tender, not only at its tip, as sometiines occurs in cases of simple otitis media, hut especially over the emissary vein and the antrum; and in some cases there is e\idence of peri- osteitis. In children j)us often makes its way outward alon<^ the petro-mastoid suture, bulges beneath the periosteum, and causes the auricle to stand away from the head in a very characteristic manner (Fig. ()7()). In rarer cases an abscess forms deep in the neck beneath the sterno-mastoid muscle (BezoIcVs abscess). In adults movement of the auricle is not painful; this is an impor- tant differential sign from furunculosis of the external auditory meatus. But in children, in whom the bony canal is less well developed, mo^■ement of the auricle is communicated to the middle ear and hence usually causes pain. Diagnosis. — This rests on the previous history of the case, namely, onset of ear trouble usually in convalescence from an acute infectious disease; on the existence, past or present, of chronic otitis media; and on ])hysical examination of the ear, showing mastoid tenderness, redness, and edema, perhaps with protrusion of the auricle. Prognosis. — If the infecting organism is the staphylococcus or even the pneiunococcus, recovery without operative treatment (other than myringotomy) may occur in a fair proportion of cases. Where the streptococcus or the Bacillus mucosus capsulatus is found, bone destruction is apt to be much greater, and very seldom can operation be avoided. Treatment. — In cases which develop soon or immediately after the first appearance of an otitis media, operation on the mastoid may be delayed one or two days, to ascertain what effect the myringotomy will have on the mastoid symptoms. But if the B. mucosus capsu- latus is found in the discharge from the middle ear no delay in operating should be permitted; operation should not be postponed even until the next day. When the streptococcus is fountl delay never should be longer than one week, even when clear signs of mastoiditis are I II,. G7lJ. — Mastoid abscc.-^s (left; pointing through petro- mastoid suture. Age three and a half years. (Dr. Gibbs'scase.) Episcopal Hospital. 632 SURGERY OF THE FACE, MOUTH, AND NECK lacking. Prom])t drainage of the infected bone is demanded. There is great risk of sinus tlironibosis (p. 577) or l)rain al)scess (p. 579) if there is delay, especially in cases occurring as exacerbations of long standing middle-ear disease with inefficient drainage. Operation for ^ic7itc Mastoiditis. — An incision is made from the tip of the mastoid process upward, parallel with and about 5 mm. post- erior to the attachment of the auricle, for a distance of two or three inches. This incision passes directly to the bone, but as in children the bone is very soft, great care should be taken not to cut too deeply. If the posterior auricular artery is di\ide(l, it should be clamped and ligated at once. The periosteum is then separated from the bone throughout the length of the incision, for a space of nearly an inch in width, exposing the posterior wall of the external auditory meatus, and the siijjranicatal spine of Henle. The sternomastoid muscle is Fia. 671. — Macewen's triangle, outlined on the skull; and the suprameatal spine of Henle. then detached from the mastoid tip, cutting it close to the bone. If more room is required at any stage of the operation an incision is carried backward from the centre of the post-auricular incision, and the two triangular flaps so formed are elevated from the bone. The surgeon next identifies the suprameatal triangle (Macewen, 1893), which lies above and behind the external auditory meatus; it is bounded in front by the bony wall of this canal and the suprameatal spine, above by the posterior root of the zygoma, and posteriorly by a line joining these two (Fig. 071). This triangle is the guide to the situa- tion of the antrum, over which it lies. In children the antrum lies at a higher level than in adults, in whom it is more behind than above the meatus. Usually the bone directly covering the antrum is per- forated by minute venous channels, and the antrum may be located in this way. The antrum may be opened first (Fig. 672), as advised by Macewen; or the surgeon may first remove the cortex overlying si'RCEin' or THE ear (i.33 tlio niiistoid cells, iVoiii the tip of tlic mastoid up to the iiiitrimi. If a dental (.'ii,i,niu' is a\ailal)k', a rotary hiirr is a wry satisfactory iiistru- nu'iit. I siially, however, a ^ouf^o and mallet are used to remove the cortex, and then the pneumatic cells are excavated by a bone curette or fine ^ou^e forceps. In youn^ children a stronj^ curette will remove the cortex also. The instruments should be made to cut from within outward, unless the parts are fully exj)osed. The entire mastoid, includiuff its tip, should be removed; and in most cases all the pneu- matic cells which are accessi})le, wherever situated, should be removed, inclu(lin the patient is extremely septic it undoubtedly is better merely to secure free drainage, and to leave the C()ni])lcti()n of Fig. 672. — Operation upon the mastoid antrum. The antrum (a) has been laid open and gouged out, and the bridge of bone (b) between it and the external audi- tory meatus is seen. (Cheyue and Burg- hard.) Fig. 673. — Operation upon the mas- toid antrum. A bent probe has been introduced from the antrum to the middle ear. (Cheyne and Burghard.) a radical operation for another occasion. But in every case, without exception, it is necessary to open the antrum, and thus accomplish the purpose of the operation, the securing of free drainage of this region of the middle ear through the mastoid. As the bone is being removed it should be repeatedly examined by the probe; the antrum is recog- nized by the probe passing first upward, then forward and inward into the middle ear (Fig. 673). A probe introduced into the middle ear through tlie jjerforated tympanic membrane may be an aid in locating the antrum. The structures in most danger of injury are the sigmoid siinis, the facial nerve, and the horizontal semicircular canal. If a gouge is used, cutting from without inward, it should be bevelled on its convex surface, and should be applied very obliquely to the surface of the skull, so that if the lateral sinus is exposed it will be pushed ahead of the gouge and not wounded. Usually the inner 634 SURGERY OF THE FACE, MOVTIl. AM) XECK (vitreous) layer of the mastoid process, which separates the sinus from the pneumatic cells, may be recognized when the latter have been cleared away. If there is reason to suspect sinus thrombosis, this bone must be removed also, and the sinus treated as recommended at page 577. The facial ner\e is in most danger as it passes outward and slightly backward beneath the floor of the (iditus ad antrum. The horizontal semicircular canal projects into the median wall of the aditus ad (iiitniDi. The curette should not be used in either of these situations. The roof of the antrum and the aditus is very thin, and the middle cratiial fossa lies directly above it; but this will not be opened if no lione is removed above the line of the temporal ridge (continuation of the posterior root of the zygoma). The condition of the bone forming the tegmen antri should be ascertained by very gentle probing. If it is carious or perforated it should be removed gently with curette or gouge forceps, since there may be an extradural abscess above it requiring drainage. The treatment of intracranial abscess has been considered at page 581. When the operation is concluded the cavity is lightly tamjjoned with iodoform gauze, and the skin incision closed except at the lower angle. An aseptic dressing is applied, and the head bandaged. The after-treatment requires great care. The patient is confined to bed for several days; and the wound is dressed on the third day. and the gauze packing renewed. Not until firm granulations have formed should syringing be employed, but the sinus left by the operation and the external auditory meatus may be gently cleansed with pledgets of absorbent cotton moistened with dilute hydrogen peroxide. The subsequent care is that for any granulating surface. In the most favorable cases healing is complete in from four to six weeks. SURGERY OF THE LIPS AND PALATE. Hare-lip and Cleft Palate. — These, which are conveniently con- sidered together, are the most frequent congenital deformities of the face. They are best understood by reference to the accompanying diagram (Fig. ()74), which represents an embryo of three weeks. The fronto-nasal process (a) is descending between the maxillary ])rocesses (b h). The eyes are represented by c r. and the mandibular processes by d d. Failure of the embryonal maxillary processes to coalesce in the median line leaves a fissure of varying extent in the upper lip and palate. // the fissure is single, it does nqt occupy the median line but cor- responds to the line of junction between the intermaxillary bone (fronto-nasal process) and the superior maxilla. But a cleft of the soft palate, antl one of the back part of the hard jialate is in the median line, as the frontal process (intermaxillary bonej does not extend backward so far. In a complete double cleft of the palate, therefore, the fissure is Y-shaped, double in front, and single behind. Srix'af'Jh'y OF THE Lll'S AM) I'ALATE 035 //' fin- fi.s.snrc is double, the iiitennaxillary Ijoiic usually projofts in front of the lip ( Fij;. (17")), and the fissures may inxoKc hotli |)alat(' and lij). or citluT one to the exclusion of the other. As a f^eneral rule it may he said that cleft i)alate without hare-lip is very rare, while hare-lip without accompanying deformity of the palate is fairl\' conunon. The projwr aijc for opcnifidii always has heen a matter of discussion. As the existence of cleft i)alate is a more serious disability than that of hare-lij), it should take |)recedence in matter of operation. Where there is no deformity of the palate, the best time for ojxTation on the lip is from six weeks to three months after birth. Those surgeons who have most experi- ence with these deformities have come to share the opinion of Brophy, of Chicago, who since 1900 has been urg- ing that the best age for operation on the palate is between the age of two weeks and three months. When not contraindicated, the hare-lip may be repaired at the same time. But the palate should be repaired before the lip. Infants with cleft palate and hare-lip usually are stronger soon after birth than subsequently, owing to the difficulty of suckling them. In such young patients operation may be done without an anesthetic if absolutely necessary; they have no apprehension of pain or suffering to come, nor any memory of it after it has past. Fi(i. r)74. — The hoatl of an cni- hryo of three weeks. (See text.) Fig. 675. — Double hare-lip and cleft palate. Age two days. Note the projecting intermaxil- lary bone. Orthopaedic Hospital. Fui. 676. — Hanging head position, for operations on the palate. But in most cases there is no contraindication to the use of ether or chloroform. Ether is preferable in older children and in adults. It is administered in the "hanging head" position (E. Rose, 1874), and the surgeon stands at the patient's head, thus getting a good view of the inverted palate (Fig. ()7()). The use of a mouth tube for anesthetization is a great convenience. Hare-lip. — Sitigle hare-lij) varies from a mere notch to a fissure extendi;ig into the nostril, and perhaps continuous with a unilateral 036 SURGERY OF THE FACE, MOUTH, AND NECK cleft of the palate. The principle of the operation consists in freshen- ing the edges of the fissure and suturing them together. The lip is Fig. 677 l"iG. 07S Figs. 677 and 678. — Nelaton'.s method for iiifomplete single hare-lip. first freely separated from the u])per jaw, by (li\iding the frenum or other adhesions. Bleeding should be controlled promptly by mos- FiG. 679 Fig. 680 Figs. 679 and 680. — Malgaignc's method for complete single hare-lip. quito hemostats. If there is a mere notch in the lip it is sufficient to employ Xelaton's operation (Figs. ()77 and ()7S) ; usually, however, it is better to pare both edges of the fissure in a line slightly concave toward the median line. The knife is entered at the apex of the fissure for denuding each margin; and care is taken that these incisions unite above the apex of the fissure and that enough of each flap is left at the free border of the lip to ensure a projection on the vermilion border when the edges are vmited (Figs. 079 and 080; Malgaigne's operation, 1844) ; if the ver- milion border is sutured flush, the con- traction of the cicatrix soon will cause a depression. Interrupted sutures of fine silkworm gut or horsehair are used. They are introduced from the cutaneous surface down to but not tlirough the mucous membrane. Fig. 681. — Hare-lip pins in use with twisted suture; points of pins cut off and wrapped in adhesive plaster. SUltGERY OF THE LJl'S AM) rALATE y'uu Or hare-lip pins and a twistrd suture may be used for the main sup- j)()rt, with superlicial iuterrupli-d sutures to secure accurate coaj^tation Fiti. (582 Fiu. 083 Figs. 082 and 083. — Owen's nietliod for coniijlete siiiKlc liarc-lip. (Fig. (iSl). If the fissure is hirger than a mere notcli, it is better to adopt some form of phistic operation, as indicated in I'igs. ()S2 and Fig. 084 Fig. 68.5 Figs. 684 and 685. — Method of improving the shaj e of tlie iK-.stril. (Stone.) (i83. To improve the nostril, a wire suture shotted at both ends may be passed as indicated in Figs. 684 and 685. Fig. 086 Fig. 687 Fig.s. 086 and 687. — Hagedorn's method for double hare-lip. Double Hare-lip. — The operation here is the same as in cases of single hare-lip, the margins of each fissure being freshened and sutured separately; but often it is well to bring a small flap from the larger side across beneath the intermaxillary bone, to form the prolabium; and 08S SURGERY OF THE FACE. MOrril, AXD XECK if there is sufficient tissue a second still smaller flap from the other side may be introduced between this flap anrl the intermaxillary bone If the intermaxillary bone protrudes and cannot be pushed back intf) place even by division of its attachment to the septum, it may be excised; but as it bears the central incis(jr teeth this should not be done recklessly. After the operation the parts are painterl with Whitehead's varnish,' and a long strip of adhesive plaster is applied from one ear to the other across the upper lip. The baby should be put to the breast or fed from a bottle as soon as convenient, as the motions involved in sucking tend to lessen tension on the sutures. Minute doses of paregoric may be reqiiirefl to check crying. Everv alternate stitch may be removed about the fourth or si.xth day, and the remainder from the eighth to the tenth day. Cleft Palate. — If the operation is done in early infancy the max- illar\" bone- are cartilaginous, and may be brought into apposition by moderate pressure. This permits suture of the vivified margins of the cleft without tension, and restoration of normal relaticms of the parts concerned in phonation before the child begins to talk. If the operation is not done until after the age of two years, and par- ticularly in older children and adults, a much more flifhcult and terlious method will have to be employed, and the patient will have acquired improper habits of speaking which he never will be able completely to abandon. When the operation for cleft palate is confined to the -oh palate, it is known as fstaphyJorrhaphy: if it involves the hard palate it is called uranoplasty. Before operatitjn is undertaken it is important that the patient be free of coryza, pharyngitis, or other inflammatory ronditions of the upper respiratory tract. Early operation. — This consists essentially in passing sutures of heavy wire across the cleft f^above the horizontal process f)f the palate bone; from the buccal surface of one maxilla to that of the other (Fig. (i88). These sutures are then twisted tightly together over perforated learl plates; and when the maxill* are thus approximated the margins of the palatal cleft (pre- viously denuded) are sutured together with interrupted sutures of silkworm gut. The wire sutures are removed after four to six weeks* Though some slight pres- sure ulceration may occur beneath the lead plates no permanent harm is done. Late Operation. —Here the maxilla cannot be approximated, and it is necessary to close the cleft solely by means of the soft parts. The ' Whitehead'.s varnish i.s made Vn- substituting for the spirit ordinarily u.sed in the preparation of "Friar's Balsam" (compound tincture of benzoin;, a satu- rated ethereal solution of iodoform, adding one volume in t«n of turpentine. Fig. 688. — Wire sutures pas.sed, for uranoplasty in infancj-. s(ii(;Kin' OF THE Lirs amj i'alaik (•»;;<) marjiins of tlic clct't arc tVeslu'iicd first; usually tlicy caiuiot he niacle to meet e\cii under j^reat tension. Then an incision is made tliroufjh the mucous membrane and periosteum of the hard palate close to the alxcolar ])rocess; this is not carried so far posteriorly as to divide the tnnik of the descendinu palatine artery as it emerges from the posterior palatine foramen, and it is placed so close to the alveolus as to lea\c most of the branches of this artery on the median side of the incision. Blccfl- ing, which usually is very free, is controlled by pack- ing the incision with gauze which is allowed to remain, while a similar incision is made in the palate of the other side. The mucous membrane and periosteum are now separated from the hard palate by suitable periosteal elevators from these lateral incisions to the median cleft (Fig. ()S9). Even when these flai)s have been thus freed, it may be impossible to make the edges of the cleft meet in the median line without undue tension. The higher the arch of the palate the easier will it be to make the flaps meet, when thus separated fnmi the palate above. To overcome the remaining tension it may be I'm. (3.S9. — Separating the luufo-jjeriostoal flap in the operation for cloft palate. I''iG. 090. — Cnttinji the aponeurosis (jf the velum at its insertion in the hard palate. Fig. 691. — Introduction of sutures, in the operation for cleft palate. necessary to divide the aponeurosis of the soft palate at its attachment to the hard ])alate. This is accomplishetl by use of scissors bent on the flat almost to a right angle; one blade is inserted l^etween the detached mucoperiosteum and the under surface of the back of the hard palate, and the other along the nasal surface of the soft palate 640 SURGERY OF THE FACE, MOUTH, AND NECK (Fig. ()90). The freshened edges of the cleft are finally united hy inter- rupted sutures of silkworm gut, passed by means of special mounted needles, as indicated in P'ig. 691. The sutures may be secured by clamping perforated shot over their ends. The wound is then covered by Whitehead's paint. In the after-treatment the patient, especially if an infant, must be kept with the head low, and so placed that vomited matters, mucus, blood, etc., find a ready exit. If no marked opposition is encountered it is well to spray the mouth and nasal cavities with some Aveak anti- septic solution e\ery three or four hours. Speaking should not be permitted for a week at the least. Liquid diet, meat juices, or broth being preferable to milk, should be employed until after removal of the sutures, when soft diet may be allowed. The sutures should not be removed for ten days unless they begin to cut out sooner. If the opera- tion is not a success, from partial or complete sloughing, another attempt should not be made for at least a month, so as to allow the inflammatory swelling to subside. Acquired Perforations of the Palate, the result of syphilis, of trauma, or of sloughing following infection, are very difficult to close by opera- tion, and none should be attempted imtil the parts are in healthy condition. Usually a flap of mucous membrane must be inverted from one or both sides of the perforation. These are sutured together and the denuded area left to heal by granulation. In cases not admit- ting of operative relief some form of obturator should be worn in the form of a plate attached to the teeth. The obturator never should be introduced into the perforation itself, as this would surely cause it to grow larger by atrophy from pressure. Macrocheilia. — Abnormal size of the lips, usually the lower, may be due to a congenital condition of lymphangiectasis. This often does not cause marked deformity until the age of puberty. Or the condition may be acquired as the result of hyper- trophy following recurrent attacks of cellulitis (Fig. 692). It frequently is ac- companied by an adenomatous condition of the mucous glands of the lip which may be palpable as shot-like nodules beneath the mucous membrane. The treatment, if any is demanded, consists in excision of a wedge-shaped section all across the lip, with suture of the mucous to the cutaneous border. Cysts. — Cysts of the labial mucous glands form small, rounded, submucous tumors. They may follow biting the lip. If punctured the cysts are apt to refill, so it is better to excise the anterior wall and cauterize the lining membrane. Fig. 692. — Macrocheilia in a boy of seven and a half years; not congenital; followed cellu- litis from injury at eighteen months of age. Orthopaedic Hospital. SURGERY OF THE LIl'S 04 1 Carbuncle. ('ail)Uiiclc', wIk-h it atlccts tlie upper lij), is lui unusu- ally serious form of the disease, from the danger of intracranial com- ])lications hy thrombosis and enii)olisni through the facial and angular wins. Bullock recently has collected notes of 27 cases, witji six deatJis, a mortality of 22 per cent. He advocates and practised with success in one case, early ligation of the facial veins about half an incli l)elo\v the inner canthus of each eye. Early and free incision of the car- buncle is inii)ortant, regardless of aj)i)arent deformity, as this may be remedied later by skin-grafting or i)lastic operation. Epithelioma. — Epithelioma of the lip is a frequent condition, and for successful treatment rccjuires early recognition. Ercfpientiy it follows clironic local irritation, notably tlie heat from a short-stemmed clay pipe; the explanation is that the moistened e])ithelium sticks to the absorbent clay and is peeled off the lip as tJie pipe is removed. An exfoliation residts, with a tendency to keratosis. Less than 9 per cent, of cases of epithelioma of the lip occur in women; in men there is only one case in the upper lip to 45 in the lower, while in women there is one in the upper to every 7 in the lower lip (Butlin). The lesion usually begins to one side of the median line on the vermilion border of the lip (muco-cutaneous junction), and almost without exception is of the more malignant deep-seated type of epithelioma. An epithelioma begiiming on the cutaneous surface of the lip often is of the less malignant superficial type (rodent ulcer). The deep-seated epithelioma growing on the vermilion border of the lip may arise in a seborrheic patch, or as a primary papilloma. The former is much commoner. The lip is supplied by a row of seba- ceous glands which often are visible in lips that appear to be normal, " as a slightly shaded or as a glittering band that stretches like a bow across the front of the lips between one corner of the mouth and the other," about half a centimeter above the cutaneous border (Mont- gomery). Somewhere on this line, crusts tend. to form, and a typical seborrheic patch develops. Early invasion of the regional lymphatics occurs; but they are microscopically infected long before they become palpable. They should be searched for carefully, the finger of one hand being placed in the floor of the mouth, and the fingers of the other hand beneath the chin. The submental nodes are those first affected, then those around the submaxillary salivary glands (both sides), and finally the deep cervical lymph nodes along the great vessels. The nodes at first are indurated, and usually painless; but rarely are they distinctly palpable until the labial ulcer has existed for many months. As already remarked, long before they are palpable, probably within three or four months of the appearance of the lip lesion, microscopical examination of the submental nodes will show the presence of carcinoma cells. As time goes on, the labial ulcer becomes a foul, fungating, stinking crater; the cervical lymphatics form conspicuous tumors; they adhere to the skin and form secondary ulcers of the same foul character as in the lip. The patient cannot eat; the stench renders him loathsome 41 042 SURGERY OF THE FACE, MOUTH, AND NECK to himself and every one near him; strenfjtli fjrachially fails; hemor- rhaj?es from the growth may oecur; the trachea or esophagus may he compressed; and he dies a miserable and painful death, hut not as rapidly as he could wish. Diagnosis. — The diagnosis seldom ofi'ers much difficulty. Epithe- lioma occurs very rarely in ])atients under middle age; it is predis- posed to by exposure to weather, by chrt)nic local irritation of any kind; the area affected is covered with adherent crusts, which reveal a small bleeding ulcer when remo\'ed; from the surface of the ulcer it may be possible to squeeze out the epithelial i)earls and columns of cancer cells lining the sebaceous ducts; the crusts soon form again; and the regional lymph nodes are not palpably enlarged until the lesion has existed for a number of months. A chancre of the lip is of much more acute dcAelopment; may cccur at any age; is frequent on the upper lip; presents parchment-like induration; does not tend to scab but has a macerated or sloughy surface w^hich is very little inclined to bleed; a history of contagion usually can be elicited; lymphatic enlarge- ments occurs within a few weeks, the nodes being soft and juicy on palpation; microscopic examination of smears from the lesion usually will reveal the presence of the Treponema pallidum; in due time skin lesions make their appearance; and antisyphilitic treatment is curative. A (jumma of the lips is quite rare; it is painless; there is no lymphatic enlargement; the history or evidence of other syphilitic lesions usually can be obtained; and antisyphilitic* treatment is rapidly effective. Prognosis. — The expectation of life in cases in which no operation is done is from three to five years from the commencement of the disease, and about eighteen months from the time of dift'use lymphatic involvement. If radical operation is done before the lymphatics are })erceptibly enlarged, from 50 to 60 per cent, of patients will be free from recurrence three years later; of those in whom recurrence takes place a small proportion can be permanently cured by a second opera- tion, and the others will have an expectation of life dating from the period of recurrence. Recurrence is much more apt to develop in the lymphatics than in the lip; and a growth which develops in the lip may not be a recurrence, strictly speaking, but a development of a new epithelioma from a seborrheic patch in the neighboring skin used in forming the new lip at the first operation. Treatment. — A lesion on the lower lip which is merely suspected of being carcinomatous should be excised, with a margin of at least a quarter of an inch on all sides, and subjected to microscopical exami- nation. If there is no evidence of malignancy this operation may be regarded as sufficient. If the patient refuses to have the suspected patch excised, treatment as for keratosis senilis (page 622) may be instituted ; but the surgeon should not forget that he is dealing in the lower lip with a very different form of epithelioma from the rodent ulcer where such treatment is in a few cases successful. There need be no anticipation of success if the growth on the lower lip is really an epithelioma. If such a lesion is either clinically or microscopically .si.yi'(,7t7»'r OF rill': iJi'S M'A innlimKiiit, it is lunrssary to remove the udjacciit lymph nodes :ilso. 'I'lie growth on the lower lip should then he exeised with a mar^nn <)l' at least a half inch on each sid'', hy incisions at ri,u;ht angles to the line of the lip, not hy a \-shaped incision. The ()peniti(.n introduced by (Jrant, of 1 )<'nver (1899), usually is cnii)loyed now (Fi^^. ()9;> and (■)94). After excision of the lesion, usu- all\ including- most of the lower lip, in form of a rectan^de, incisions are carried downward and outward from the lower angles of this rectangle, so as to expose the suhiuaxillary region on each side. These regions are then cleared of lymi)h nodes, ligating the facial vessels if necessary. Finally the submental l.\ ni])h nodes are removed through a separate median incision. By drawing together in the median line the fiaps outlined hy the two lateral incisions, the lower lip is well restored without further i)lastic ])rocedure. The other chief merit claimed Fig. 693. — Grant's operation for epithe- lioma of the lower lip. Fig. 694. — Grant's operation completed. for this operation is that it leaves the point of the chin untouched, and that this serves as a firm basis of support for the new lower lip. But it will be noted that this method of operation does not remove the labial growth in one mass with its related lymphatics, but extir- pates the diseased tissue in three or four separate sections. ^Moreover, the cavity of the mouth is opened as the first step in the operation, exposing the entire wound to contamination during the tedious dis- section of the submaxillary and submental regions. For these reasons I think it is l)etter to commence the operation by the removal of the submental and su})maxillary lymphatics. These regions are well exposed b\- making a long cur\'ed incision which cor- responds to those incisions of Grant's operation which are represented hv solid lines in Fig. 693. The skin over the point of the chin may be left attached by carrying this first incision a little lower than indicated. The flap thus outlined is (tissected dowaiward, including with the skin (544 SURGERY OF THE FACE, MOUTH, AND NECK only the platysma, and leavinj^ the fatty and lymphatic tissues m situ. When the submental and both submaxillary regions have been exposed in this way they are cleared of lymphatics and fat by dissection from below upward; and the diseased structures are removed. Incisions are then made upward into the mouth on each side of the labial growth, and the lower lip is excised. The submental flap is then sutured to the point of the chin, and the lateral flaps are united in the median line as in Grant's operation. It is well to drain both sub- maxillary regions from the outer angles of the lateral incisions for several days. Where the dissection has been very extensive it is better to carry a tube from the submental region in the median line through the floor of the mouth, draining the buccal secretions directly into the dressings, and thus lessening the chance of infecting the suture lines. The portions of the skin incisions not drained should be painted with Wliitehead's varnish (p. 638). SURGERY OF THE TONGUE. Tongue-tie. — It happens occasionally, though not so often as mothers believe, that an infant is born with congenital shortness of the frcBmim lingncB. The tongue then is held against the floor of the mouth, cannot be protruded beyond the alveolar margin, and may occasion slight difficulty in suckhng. The condition is easily remedied by snipping with scissors the tense band close to the floor of the mouth (to avoid the ranine vessels which run beneath the tongue), and then stripping the tongue upward by the fingers as far as needed. The bifid blade at one extremity of the grooved director (Fig. 700) is a convenient retractor to hold the tongue away from the floor of the mouth, while the frenum is being divided. If the separation of the tongue from the floor of the mouth is carried too far, there is danger of the baby being suft'ocated by "swallowing" the tongue. Macroglossia. — Abnormal enlargement of the tongue, when not dependent upon constitutional causes, such as cretinism, may be congenital or acquired, as in the pathologically analogous condition of macrocheilia (p. 640), and from similar causes. In congenital cases the patients usually are mentally deficient. The protruding tongue becomes inflamed and dry from exposure to the air, resulting in stomatitis, with collection of sordes, fetor of the breath, etc. In time the incisor teeth of both jaws are pressed forward and the alveolar processes are distorted ; but this deformity rarely becomes permanent before the tenth year. Treatment. — Treatment consists in partial excision, usually of a wedged-shaped portion of the tip of the tongue, with suture of the remaining lateral flaps in the mid-line. Or, as the thickness of the tongue usually is more obnoxious than its breadth, a transverse resec- tion may be done, making superior and inferior flaps. Preliminary ligation of the lingual arteries may be advisable if the tongue is very large, and Armstrong recommends the use of silver wire instead of HVIiCEUY OF THE TONGUE 045 silkworm mit for suturing the tonjiuo. The best time for operation is from the third to the sixtii year. Ranula. UaiuiUi is a eystie tumor between the tonj^ue and the floor of the moutii. It is a ehnieal term, possibly deseriptive of the frog- like appearance of patients when the growth is very large. Though occasionally congenital, in the vast majority of cases it is acquired; usually it is considered a retention cyst of one of the sublingual glands or its duct. It is not improbable that its pathogenesis is similar to that of galaetocele (p. 703). Occasionally a salivary calculus may be the cause of obstruction of the duct, but as a rule no cause can be found. The cyst in most cases is of slow development and chronic in (hiration. It is unilocular. Conditions described as acute, and as inter- mittent ranula are also recognized, though very rare. In the acute cases a swelling suddenly a])pears beneath the tongue, the mucous membrane lining the floor of the mouth is raised above the dental border, salivation is profuse, speech, deglutition, and even respiration are interfered with, and suffocation may threaten. Astringent washes usually are sujQficient to relieve the symp- toms, and the cystic swelling may disappear as rapidly as it came, as w^as the case in the only patient with this rare af- fection I have seen; but some- times incision is required. In the chronic cases the cyst, though unilateral at first, may spread so as to involve the entire sublingual region; very seldom at the present day is it allowed to grow so large as to project in the submental region. The mucous membrane slides freely over it, and its surface often is covered with dilated and tortuous veins (Fig. 695) ; it is semi-trans- lucent, and the contents are a viscid, ropy, mucus. Ranula is most likely to be confounded with dermoid cysts, which, however, are rare; a dermoid cyst has thicker walls, pits on pressure, and is not trans- lucent. Treatment. — Excision of the anterior wall of the cyst, and scraping or cauterizing the remaining portion of the lining membrane, and packing the cavity with gauze until healing by granulation takes place, usually effect a cure. But unless a thorough operation is done and the after-treatment efficiently conducted, recurrence will take place. The operation can be done under cocain anesthesia, through the mouth. Ludwig's Angina, or Angina Ludovici, is a condition first accurately described by Ludwig in 1834. It is an acute septic inflammatory Fig. 695. — Ranula. Age eleven years; duration over one year. Projecting cyst is dark blue from overlj-ing vein. Episcopal Hospital. ()4() SURGERY OF THE FACE, MOUTH, AND NECK process involving the cellular tissues of the floor of the mouth and the submaxillar!/ region of one or both sides of the neck. It is imjjortant to note that in this definition the main chnical features of the disease are indicated. It affects the coiniective tissue spaces, being a ceUuhtis, as asserted by G. G. Davis (190G), not a lymphangitis; the lymph nodes and the submaxillary and sublingual salivary glands are not primarily diseased, but may be invaded secondarily. It involves both the floor of the mouth and the cervical tissues. It is not confined to either. Usually it owes its origin to infection from dental lesions, and often commences after the extraction of teeth; but it may begin in the tonsil or other intrabuccal structure. The cellulitis spreads with great rapidity from the floor of the mouth around the posterior border of the mylo-hyoifl muscle, a route to which attention was called by T. T. Thomas in 1907. Both sides of the neck are affected. The submaxillary gland and lymph nodes usually are found more or less intact in the centre of a necrotic area of cellular tissue. It is not unusual for groups of patients to be affected nearly simul- taneously, but the disease does not seem to be contagious. Symptoms. — The onset of the disease is marked usually by difficulty in talking and swallowing, pain in the floor of the mouth, salivation, and finally dyspnea. The patient becomes profoundly septic, but gives evidences of little or no constitutional reaction. The temjiera- ture often is not very high, nor is there marked leukocytosis. Edema of the glottis may occur at any time, and T. T. Thomas believes this is the usual cause of death; but in many cases death seems to be due to toxemia, and suft'ocati^'e symptoms are entirely absent. Diagnosis. — The diagnosis depends on recognizing a possible cause; on demonstrating a cellulitis both in the floor of the mouth and in the upper cervical regions, perhaps extending to the clavicle, and often more marked on one side; and on the rapid progress of the disease to a fatal termination unless relieved by efficient treatment. Treatment. — As soon as the diagnosis is made, and without waiting for the development of more serious symptoms, the parts should be incised. This may be done under local anesthesia; general anesthesia may be out of the question, owing to the sufl'ocative symjitoms. An incision is made directly in the median line in the submental region, between the genio-hyoid muscles; the knife is pushed up into the floor of the mouth, emerging just behind the symphysis menti. There are no structures of importance in the median line. A drainage tube is then drawn through from the submental region to the floor of the mouth. An incision is then made in one or both submaxillary regions, and a tract is made by thrusting a hemostat into the mouth through the mylohyoid muscle. Tubes are then inserted in these additional tracts; or one long tube may be made to pass from one submaxillary region to the other across the floor of the mouth a})ove the mylohyoid muscle (Fig. 696). In addition, if the sublingual tissue is markedly edematous, it is well to incise the mucous membrane of the floor of the mouth from the mid-line to the second molar tooth, as advised bv J. W. Sl'h'dl'Hn' OF THE TOXdl'K (;i7 Fig. 696. — Ludwig's angina, in a patient of twenty-two years. After operation. (Dr. J. W. Price, Jr.'s ca.se.) Episcopal Hospital. Price (190S), and 3 «23 SC lO <» Q'SS 3^ o ■^ 0-- -r O. ■^ cc tn t. (-. 5 o oi D. o OJ O 3 W o-o — o si «3.« 3 £ a ^■^^ SURGERY OF THE TONGUE G40 relieve the pain l)y loeal use of cocain or other anesthetic. Armstrong says si)rayin^- the all'ected area with ;i 1 per cent, solution of carh(jlic acid, to which a Httle sodium hi( arhonate has heen added, sometimes is soothing. Syphilis.- -Syphilis of the tongue is of most surgical interest in the gununatous stage. Chaiicrr and )iincou6- paiclici of the tongue and mouth present the same characteristics as these lesions elsewhere, and their diagnosis seldom is difficult. Gumma of the tongue may be single or multiple, superficial or deep. The lesions occur chiefly on the dorsum of the organ; they soon break down, and are a])t to coalesce, forming large irregular, nearly painless ulcers with overhanging edges and covered with an adherent slough. The ulcers do not tend to bleed when the slough is pulled away; they are not indurated; they are not accompanied or followed by enlargement of the cervical lymph nodes; a history of i)revious syphilitic lesions usually can be obtained; and they rapidly improve under the administration of the iodides. These features serve to distinguish them from carcinomatous ulcers (p. 650). Diffuse gummatous glossitis as it heals leaves a charac- teristically fissured and furrowed tongue (Plate IV, Fig. 2). Sarcoma.— Sarcoma of the tongue is very rare. Serafini, in 1910, reported what he believed w^as only the thirty-second case on record. Carcinoma. — In the tongue this occurs almost invariably in the form of ei)itlielioma, though a few cylindrical-celled carcinomas have been recorded. It is much more common in men than in women (about 15 to 1), and quite unusual before middle life. Frequently it seems to be brought on by chronic irritation, such as that from a broken tooth, from tobacco smoke, or the stem of a pipe (Plate IV, Fig. 3). The pre-cancerous lesions of the tongue already have been discussed (p. 647), and Butlin demonstrated not long ago that many lesions, previously considered by him and others as pre-cancerous, prove on microscopical examination to be actually malignant. Usually the epithelioma begins in a fissure, an ulcer, or a patch of leukoplakia. Sometimes, but rarel}', it appears first as a wart or papilloma; and any such growth on the tongue which does not disap- pear very promptly after removal of a recognized source of irritation should be considered malignant. The epithelioma commonly appears on the lateral margin of the tongue, very rarely at the tip, and almost never on the dorsum. It begins occasionally as a submucous growth, but even in such cases it is very seldom seen until an ulcer has formed ; and in the vast majority of instances it develops in a preexisting erosion or ulcer. It may begin in the floor of the mouth, but it is more usual for this to be invaded secondarily. A cancer in the ante- rior third of the tongue tends to spread to the floor of the mouth and mucous membrane covering the alveolus; it early invades the sub- mental and submaxillary lymph nodes, first those on the same side as the grow^th, but later the involvement is bilateral. Next the deep cervical chain is invaded. The submaxillary and sublingual salivary glands usually are not invaded. A cancer in the yosterior two-thirds 650 SURGERY OF THE FACE, MOI'TH, AXD NECK of the tongue tends to spread to the soft palate and pharynx; it invades the lymphatics of both sides very early; first the submaxillary, then the deep cervical. When the latter have been invaderl by cancer arising in any part of the tongue, the growth spreads up their chain to the base of the skull and downward to the clavicle. Distant metastases occur very late and are quite unusual. In the vast majority of cases the disease is distinctly limited to the face and neck. When once the cervical lymph nodes are invaded, the tumor may grow in them with alarming rapidity, and these secondary growths may quite over-shadow the original trouble. The same progressively fatal course, but even more rapidly, is observed here as in the cervical growtlis following carcinoma of the lip (p. 641). Symptoms. — Pain and smarting in the diseased area, especially on smoking, drinking alcoholic beverages, or eating hot or highly seasoned food, usually are the first things to attract the patient's attention. The tongue, or the whole mouth, may feel sore. There is difhculty and pain in swallowing, and the patient refrains from eating. Later even liquids can scarcely be taken. The tongue feels thick and clumsy. Speech becomes in- distinct. Salivation is increased. Pain may be referred to the ear if the growth is far back in the tongue. Very rarely is pain al- together absent ; but occasionally the patient is unaware of his condition until the tumor is . inoperable. From inability to eat, sleepless nights, and constant pain, the patient rapidly becomes emaciated. If secondary infection occurs, there will be added fever- ishness, chilliness, and increased secretion from the tumor, with hor- rible fetor of the breath. Hemorrhages may occur from the mouth or from secondary ulcers in the neck. Death may occur from such a complication or from septic inhalation pneumonia, but more often follows a short period of delirium due to toxic absorption. Diagnosis. — Carcinoma of the tongue must be distinguished chiefly from tuberculous and syphilitic ulcerations. The characteristics of these have been considered already (p. 648); but it should not be forgotten that carcinoma frequently develops in a syphilitic lesion. In carcinoma the main diagnostic points are the hardness of the ulcer's base; the thickness f)f its margins, the bleeding when the adher- ent slough is removed, exposing an uneven floor; the patient's age; and the existence of some chronic form of local irritation. Any ulcer even suspected of being carcinomatous should l)e subjected to micro- FiG. 697. — Recurrent carcinoma of floor of mouth. Excision of tongue by intra- buccal method in September, 1909, three months after appearance of growth. Re- currence in Xoveml)er. 1909. Photograph February 14, 1910. ^E>r. H. C. Deaver's case.) Episcopal Hospital. s[R(;KRy or the roxacE i\n\ scopical study. A portion ol' tlu' ulcer may ])v rcniowd easily hy pullin j)er cent.) beneath the ulcer; a portion of the indurated margin of the nicer is then pinched up in forceps and cut oH' with scissors. I^nlarj^enient of tlie lympli nodes never should be depended u|)on for a clinical diagnosis. Lonjj before they are palpa- ble they arc nncrosc()])icall\' diseased, ^'et the presence of enlarj,a'd lymph nodes points to carcinoma rather than to % and the bone is grasped in lion-jawed forceps and pulled downward, any remaining attachments, including the junction of the pterygoid processes with the maxilla, being severed with bone-cutting forceps or chisel. Hemorrhage is then con- trolled, if necessary by the actual cautery. The mucosa of the cheek is then sutured to that of the palate, and the skin wound closed with interrupted sutures, after packing it loosely with iodoform gauze, which is made accessible through the nostril. Frequent syringing through the nostril or any opening in the roof of the mouth is required during con- valescence. Temporary resection of the superior maxilla is done by the same skin incision, but the flap is not separated from the bone; this is divided as above described except at its malar attachment, which is used as a hinge, after fracture by leverage outward. Excision of the Inferior Maxilla. — The typical operation involves only half the mandible. An incision is made from the middle of the lower lip down to the hyoid bone, and from this point back as far as Fig. 705. — Fergusson's incision for excision of upper jaw. SURGERY OF THE TONSIL AND PHARYNX ()()3 the aiifilo of tlu' jaw, thv submaxillary structures arc dissectcl tree, and the soft part's arc separati'd from the outer surface of the bone, respecting,' the branches of the facial nerve, but liKatinf^ the facial and the linunial arteries and veins. :\iost of the external surlace ot the ranms is thus exposed. The symphysis is then divided with saw and the structures of the floor of the mouth cut with scissors, from before backward. An incision is then made alon^' the mucous membrane on each side of the ascending ramus of the jaw; the bone is forcibly depressed, and the insertion of the temporal muscle into the coronoid I)rocess is divided with scissors. The jaw is then turned somewhat outward, and the ptcryj;-oid muscles cut dose to their insertions. The liiii^nial nerve should be preserved if i)()ssible, but, of course, the inferior dental must be sacrificed. The temporo-maxillary joint mav then be opened, the few^ remaining attachments severed, and the bone removed. After careful control of all hemorrhage, the pterygoids are sutured to the masseter muscle, and the mucous menil)rane of the cheek united to that of the floor of the mouth. Finally the skin wound is closed, with provision for drainage externally. Partial ('.vci,v(»i involves removal only of the portion of bone afl'ected, after its division in front of and behind the growth. Prosthesis after Excision of the Inferior Maxillary Bone.—U the periosteum can be preserved, a shell of bone sufficient to prevent exces- sive deformitv may be formed in time. While the wound is healmg the remaining portions of the bone should be held in proper position bv stout silver wire, used as a bridge across the gap left b\- excision of the diseased portion. A sinus usually persists until the wire is remo^•ed, but bv that time the bone may be sufficiently firm. Claude :\Iartin, of Lyons, since 1878, has employed after excision of either upper or lower jaw, a temporary prosthesis made of hard rubber, pre- viouslv constructed to fit into the contemplated defect. This pros- thesis 'is riddled with channels, and though it is implanted into the wound through the buccal aspect (no attempt being made to close an^'thing but the skin), the wound and the appliance may in almost alf cases be kept clean until healing occurs by irrigation through its numerous channels. When healing is complete a permanent prosthesis is constructed. SURGERY OF THE TONSIL AND PHARYNX. Peritonsillar Abscess or Quinsy usually is a sequel of parenchy- matous am^■gdalitis. The systemic symptoms of sepsis may be marked. Localh-, in addition to the signs of the preceding tonsillitis, may be observed a diffuse swelling of the soft palate at the upper border of the tonsil. At no time is a distinct sense of fluctuation obtainable. Earlv evacuation is the only satisfactory treatment. Thrust a grooved director through the most prominent part of the swelling (usually through the soft palate), after painting it with 10 per cent, cocain (Fig. 706). The tract made by the grooved director may be enlarged 664 SURGERY OF THE FACE, MOUTH, AND NECK Fig. 706. — Puncture of peritonsillar abscess through soft palate. by inserting the closed points of a pair of dressing forceps, and with- drawing the instrument with the bla(h^s ()})ened. Tiic reHef is innne- diate, and under the use of simple alkaline mouth washes con\al- escence usually is established in twenty-four to thirty-six hours. If a peritonsillar abscess is left to burst of itself, it may do so during sleep, and has caused death from suffoca- tion. In very young children it is better to open it in the head-low position. Malignant Tumors of the Tonsil. — Either carcinoma or sarcoma may occur in the tonsil . Diagnosis is not easy. Any unilateral tonsillar en- largement in an adult should be regarded with suspicion. The possibility of syphilitic lesions of the tonsil (chan- cre and ulcerated gumma) should be kept in mind, and their presence excluded by the history of the case, the existence of evidences, past or present, of the disease elsewhere in the body; as well as by the use of laboratory and therapeutic tests. In most cases a specimen of the growth should be excised for microscopic study. In carcinoma the diagnosis usually is easily made by this means, but in sarcoma the histological picture may not be convincing. Symptoms. — The symptoms are chiefly those of obstruction, in sarcoma, with pain on deglutition; the lymph nodes seldom become enlarged until late in the disease, after ulceration has occurred. Local extension to the palate and pharynx is much more common in carcinoma, and in this affection the submaxillary and deep cervical lymph nodes are involved early, though not palpably so for a number of weeks. Treatment. — If the diagnosis is made very early in the disease, by means of microscopic study, it may be possible to enucleate the tonsil from within the mouth. Usually, however, and particularly in the case of carcinoma, the growth should be approached from the neck. In lateral 'pharyncjoiomy an incision is made from the mastoid well forward under the body of the jaw; after clearing the submaxil- lary and cervical regions, the facial artery is ligated close to its origin, so as to control its tonsillar and ascending palatine branches; the wall of the pharynx is incised on a sound introduced through the mouth, and the diseased area excised with scissors. Temporary resection of the mandible may be requisite. Approach to the tonsil, the epiglottis, and the pharynx may also be gained by suprahyoid pharyngotomy (Jeremitsch, 1895; von Hacker, 1906); in this operation a transverse SURCERY OF THE MR PASSAGES 005 incision, coiwi^N t'onvard, and al>(>ut throe or four inches I()nf,^ is niach' uhovc the hyoid hone, and all tlie inusck'S passing ujjward from tills bone are divided, inchiding both genio-hyoids, the mylo-hyoid. genio-hyot;"lossus, and hyo-- should be done, and the deformity corrected. In very mild cases," no operation is required, it being sufficient to appb" a light immobilizing dressing. In intermediate cases, especially if there is any emphysema, tracheotomy should be done as a precautionary 668 SURGERY OF THE FACE, MOUTH, AND NECK measure, since experience shows that in such cases sudden death is apt to occur from edema of the glottis. Edema of the Glottis. — Above the true vocal cords there is abun- dance of loose areolar submucous tissue, prone to edema from trauma or infection. Below the vocal cords the mucosa is tightly applied to the cartilage. The symptoms of edema of the glottis usually develop very suddenly and often quite unexpectedly. They are those of asphyxia. Treatment, which must be immediate, consists in crico- tliyrotomy or high tracheotomy (p. 670), Tumors of the Larynx. — These belong rather to the province of the laryngologist than to that of the general surgeon, except when external operations are required. In any case it is well for surgeon and laryn- gologist to act in consultation. The most frequent benign tumor is the papilloma. It may occur in patients of any age, but is most frequent in young adults. Early symptoms of hoarseness, with recurrent attacks of laryngitis, finally will be followed by those of respiratory obstruction. The diagnosis is confirmed by inspection of the larynx through a mirror introduced above its superior aperture (laryngoscopy). Benign growths usually are pedunculated; ulceration or bleeding points to mahgnancy. Pedunculated growths usually may be removed bj' intra-laryngeal methods, in the hands of a specialist. Papilloma is very apt to recur, but other forms of benign tumors rarely return. The performance of tracheotomy, with the use of a tracheal tube sometimes has served to prevent recurrence, by putting the larynx completely at rest. Carcinoma. — Carcinoma is the most frequent malignant tumor. It is said to be rare as a sequel of papilloma. Sarcoma is very rare. In many cases the growth involves the larynx secondarily, having originated in the tongue, pharynx, or esophagus ; this form is described as extrinsic carcinovm of the larynx, as distinguished from intrinsic carcinoma, arising primarily within the larynx. The symptoms are the same as in benign growths, but the patients are older (it is rare before fifty years), there is more pain, and sometimes there is sponta- neous bleeding. The diagnosis is made by laryngoscopy, and if neces- sary by microscopical examination of an excised portion of the growth. The disease usually is more extensive than it seems. Tuberculosis and syphilis have to be considered, but usually may be excluded by the history of the case, by clinical examination, and by laboratory tests. The pjrognosis of carcinoma of the larynx is bad. ^Yithout operation death usually occurs within three years, and it is a very painful death. Treatment should be radical whenever possible, and it is best accomplished h\ external operation. OPERATIONS ON THE AIR PASSAGES. Intubation of the Larynx. — This operation, introduced by O'Dwyer in 18tS,5, consists in the introduction into the larynx, by special instru- OPERATIONS ON THE Alii PASSAGES ()()9 ments passed throii^^li the iiKtutli, ol' a hollow tiilK- wliicli is allowed to remain, suspended from the false vocal cords, until the symptoms of laryiij,a'al stenosis, for which the operation was (h)ne, have sub- sided. It is employed almost solely for larynj,'eal obstruction resulting from diphtheria. The arnuimentarium comprises a set of hollow hard rubber tubes of various sizes suitable for any age up to twelve years. The approximate size is determined beforehand by means of a scale. Each tube is provided with a hole at its ui)per end through which a long thread is passed; the thread is left hanging out of the patient's mouth and enables the tube to be quickly withdrawn if necessary. The tube is tiien fitted over the obturator, which is screwed securely to the introducer. A gag is placed in the left side of the mouth, and the child (not anesthetized) is held upright in the nurse's arms, with head steadied and slightly extended. The surgeon then introduces his left fore- finger and draws the tip of the epiglottis forward. The intro- ducer is then passed backward by the right hand and the tip of the tube is guided into the larvnx by the fingers of the left hand (Fig. 709). The tube is then quickly pushed off the obturator by means of the slid- ing shaft on the introducer, and the latter with the obtur- ator still attached is with- drawn. The thread fastened to the tube is left hanging out of the mouth, until it is certain that the tube will be well borne. If the tube has been passed into the esophagus by mistake, it should be withdrawn at once, cleansed, and properly reinserted. If dyspnea is not relieved when the tube is in the larynx, a larger tulje should be inserted. If the tube is well borne, the thread may be removed after a few hours. When necessary the tube may then be removed by the extractor, reversing the steps employed in its intro- duction. The mortality due to the operation itself is very inconsiderable, but death may occur in spite of the operation. Intubation should be preferred to tracheotomy in all cases in which it is applicable. When it fails to relieve the obstruction, tracheotomy may still be done, and a tube inserted below the obstruction. In cutting operations upon the air passages the patient should be in the "hanging head position" (Fig. 676); this not only renders the parts more accessible, but avoids so far as possible aspiration of blood or gastric contents. In cases where partial asphyxia is present, no Fig. 709. — Intubation of larynx. 670 SURGERY OF THE FACE, MOUTH, AA'D NECK anesthetic is reciuired; in others local anesthesia nsiially is snfficient except where the soft parts have been inva(leelow and of the external and internal carotids above the growth, for it cannot be separated from them safely. Other structures should be preserved if possible. In one case it was necessary to remove part of the base of the skull to secure the internal carotid above the growth; and irre- parable damage has been done to both recurrent and superior laryn- geal nerves, to the hypoglossal and even the facial nerve. If it appear improbable that the operation can be completed, it should not be attempted, or if begun, should be abandoned in good time. Fig. 724. — Thyro-glossal cyst: at birth size of walnut; steady growth since. Age four years. Orthopaedic Hospital. Fig. 725. — Thyro-glossal cyst; age four years. Orthopaedic Hospital. Thyro-glossal Cysts and Fistulae.— The thyro-glossal duct in the embryo runs from the foramen cecum of the tongue through or behind the hyoid bone, in the mid-line of the neck, to the thyroid gland. If the duct fails to be obliterated, any portion which remains may become 6S2 SURGERY OF THE FACE, MOUTH, AND NECK dilated and form a cyst; and if the cyst ruptures externall\- a fistula will result. These cysts and fistulae always are in the median line of the neck. They may be above the hyoid bone, over it, below it, or the entire thyro-glossal duct may be persistent. Usuallv these cysts are noted in childhood (Figs. 724 and 725), but sometimes no trace of them IS observed until puberty (Figs. 720 and 727). The cvst slowly and painlessly increases in size, and relief is sought for deformitv or pressure effects. A thyro-glossal fistula secretes a little mucoid matter; pain may result from retention of its contents if the orifice becomes scabbed. Suprahyoid cysts are lined by stratified squamous epithe- lium; those arising lower in the thyro-glossal tract are lined bv columnar (sometimes cilated) epithelium. Fig. 726. — Thj-ro-glossal cyst, age fourteen years; duration one year. Episcopal Hospital. Fig. 727. — Thyro-glossal cj'st. Same patient as Fig. 726. Episcopal Hospital. Treatment. — Extirpation should be done, removing carefully every trace of the duct wall. Recurrence will take place if any portion remains. The dissection is difficult and should not be undertaken by an unskilled operator. Branchial Cysts and Fistulae.— These result from maldevelopment of the branchial arches and clefts of embryonic life. They are situated laterally in the neck, and thus are easily distinguished from the median thyro-glossal remains. Branchial fistulae usually open along the anterior border of the sterno-mastoid muscle, and may extend as far as or even into the pharynx. The condition is congenital, but the patient may not seek relief until adult life, and the cysts may be of insignifi- cant size until the occurrence of some injury (Fig. 728). If the cyst lies near the pharynx it will have lymphoid tissue in its walls. SURGERY OF THE NECK ()S8 Treatment. Extirpation, which is the only successful treatment, invoK cs a verv much more delicate dissection than that ot the median evsts already" mentioned; and even skilled dissectors may have to repeat the o'peration a numl.er of times. Disten.lmK the sinus with parafhn. wliich is injected hot and allowed to hanlen ni .<^itii, is a ''Branchiogenic Carcinoma (Langenbeck, 1861; Volkrnann 1882) - Occasionallv a carc-iiu.ma .levelops in a branchial cleft Diagnosis before operation is difhcult. It may resemble a tumor of the carotid bodv, but occurs in older persons, its duration is measured by ^yeeks or months, not bv vears, and it is adherent to the skin. Treatment involves extirpation of the tumor with the overlying skin. Fig. 72S. — Branchial cyst of neck; age eighteen vears; duration seven months; followed a fall. Orthopaedic Hospital. YiQ 729. — Cystic fibroma of cheek and neck; twenty-five years' duration. Weight of tumor three pounds and tive ounces. Excised by the late Prof. Ashhurst, 1896. University Hospital. Hygroma.-This is an old clinical term used to describe cervical evsts of diflerent nature. The subject has been studied recently by Dowd (1913). Some are lymphangeiomatous m character: these are congenital, usually occupy the posterior triangle, seldom cause dis- abilitv, often grow smaller and may even disappear as the patients grow older. Their removal is difficult and dangerous, and should not be attempted unless pressure symptoms render relief imperative. Often the most that can be done is to excise the anterior and parts of the lateral walls of the cyst, and pack its cavity with gauze^ looking for a cure bv granulation, cicatrization, and contraction. Occasion- allv the cvst extends into the axilla. Hemorrhagic cysts may result from traumatic or spontaneous hemorrhage into ^ p^xisting cyst Bursal cysts, occurring in preexisting bursse around the hyoid bone or thyroid cartilage, result from effusion due to trauma or constitu- tional disease. 684 SURGERY OF THE FACE, MOUTH, AND NECK Lipoma is freciueiit in the neck. Fibroma is ratlicr unusual; it gen- erally springs from the deep fascia, is slow growing; may in time undergo degenerative changes (Fig. 729), and reaches an immense size. SURGERY OF THE THYROID GLAND. Inflammation. — Inflammation of the normal thyroid gland is com- paratively rare. It is described as thyroiditis, and must be distin- guished from strumitis, or inflammation of a goitrous gland (p. 688). Acute thyroiditis, seldom leading to abscess, occurs by infection through the blood-stream in general infections such as typhoid fever, scarlatina, etc. The entire gland is enlarged and tender, and pressure symptoms are usual. If suppuration is suspected an incision should be made. If multiple abscesses exist, or if necrosis occurs, partial excision should be done. Chronic thyroiditis is much less unusual than the acute, and usually is chronic from the start, seldom following an acute attack. It occurs usually in alcoholic or arteriosclerotic adults, and may be caused by syphilis (gummatous form), tuberculosis, or prolonged use of iodin. Operation may be required for diagnosis in cases of asymmetrical involvement of the gland, or to relieve pres- sure. Ligneous or woody thyroiditis (Riedel, 1896) is believed by Delore and Alamartine (1911) at times to be one of the manifestations of what Poncet calls inflammatory tuberculosis. Clinically the diagnosis from carcinoma is difficult, and pathologists interpret the histological pictures differently. Compression of the trachea is frequent, and demands intervention. This should consist merely in resection of the thyroid isthmus. Radical operation is nearly impossible and is not necessary. The use of the .r-ray may hasten regression of the disease. Goitre. — This is a clinical term used to describe an enlargement of the thyroid gland. It is derived from the Latin word for throat (guttur). The thyroid is an epithelial gland which in embryonic life had a duct, the thyroglossal duct. The presence or absence of a goitre, and the existence or non-existence of constitutional symptoms in con- nection with it, depend on the inter-relation of secretion and absorp- tion in the thyroid gland. In fetal life there is little or no evidence of secretion. At puberty the thyroid becomes more active, and, as noted below, sometimes enlarges. In adult life whatever secretion is pro- duced is normally absorbed by the body tissues. In abnormal states there is excess of secretion, and this is either not so absorbed, and accumulates in the thyroid ("cystic" goitre); or else is absorbed and produces toxemia (hyperthyroidism). Whenever hyperthyroidism exists there is an increase in the secreting surface of the thyroid; this results either in a parenchymatous hypertrophy (without cyst formation), or in intra cystic papillomatous out-gro^i:hs (if the change occurs in a thyroid previously cystic). When instead of paren- chymatous hypertrophy, there is marked increase in the interglandular connective tissue, the amount of secreting surface is relatively decreased; this is the case in the thyroids of cretins (hypothyroidism) SURGERY OF THE THYROID GLAND ()S5 and tlic ttTin hyptTtropliic fetal thyroid is ai^jjlicd. 11' in a fetal type of thyroid the epithelial (secreting) elements are in excess, we have an adenomatous thyroid, and symi)t()ms of hyperthyroidism ma\' or may not he present. Patients in whom atrophy of secreting cells has occurred, usually as the result of pressure from accumulated and not absorbed secretion (chiefly, therefore, in cases of cystic thyroid), are those who are spontaneously cured of their toxic symptoms; in some such cases the final state may be one of hypothyroidism (jMacC"art\', 1910). Physiological enlargement of the thyroid gland often occurs in girls at puberty (Fig. 730),, the enlargement persisting for a year or more and then gradually subsiding. Sometimes enlargement recurs at every menstrual period or during pregnancy; and occasionally the enlargement which appeared at puberty never subsides. The gland is uniformly and symmetric- ally enlarged. No symptoms are present and the patient may not be aware of the existence of a goitre. Xo treatment is required. Pathological enlargement of the thyroid gland is endemic in certain regions, notably in Switzerland; it is frequent in French Canada, and in some other parts of North America. It is generally believed that this enlargement is associated in some way with the drinking water of the patients; and it seems probable that the cause is some qualitative change in the iodin constituents of the drinking water. The enlargement may be diffuse or circumscribed ("jiodular"). This classification of Kocher is in general use, and is very convenient for purposes of clinical study. Diffuse enlargement involves both lateral lobes and isthmus pro- portionately. It usually is due to more or less uniform increase in all the elements of the thyroid {follicular and parenchymatous goitre) or to disproportionate increase in the colloid material {colloid goitre). In the latter and more frequent form, the consistency of the swelling is harder, and the individual lobules appear larger and are more easily defined. A diffuse rascular goitre is one of any form in which vascularity is marked. A diffuse fibrous goitre is the result of inflam- mation and cicatricial changes in any of the forms mentioned, and is very rare. There is also a form of diffuse adenomatous goitre which it is better to classify among malignant growths. _ Fig. 730. — Pli\-.-ioli.Lri(;al goitre, in a girl of thirteen j-ears. Orthopaedic Hospital. 686 SURGERY OF THE FACE, MOUTH, AND NECK Circumscribed or nodular enlargement may occur in any of the prin- cipal forms already mentioned: follicular, colloid, or adenomatous. The colloid or " cystic" goitre is by far the most frequent form. Nodu- lar goitre is characterized (1) by the irregularity and inequality of the enlargements; and (2) by their tendency to undergo degenerative changes, such as colloid, hyaline, calcareous, etc., and to intracystic hemorrhages. Single nodules are most common in one of the lower poles of the lateral lobes; occasionally they occur in one of the upper poles; and very rarely in the isthmus or in the pyriform lobe when the latter is present. Multiple nodules may exist. As the nodules increase in size they displace the remaining normal gland structure, and may become more or less encapsulated. Occasionally a diffuse colloid goitre is converted into a goitre with multiple cystic nodules; these have little tendency toward degeneration or internal hemor- rhages. Symptoms and Diagnosis. — Diffuse goitre retains the shape of the normal gland, and rarely attains very large size. The tumor, as in all thyroid affections, rises with the larynx in the act of swallowing and in coughing. It is movable laterally, but scarcely at all up and down. Pressure symptoms are rare. Sometimes venous engorgement is visible over the root of the neck or upper thorax. In nodular goitre the relation of the swelling to the thyroid is determined by its location in the neck over the normal site of the thyroid, and by its movement with the larynx in deep breathing, sw^allowing, and coughing. The swelling is close to the median line of the neck, but usually is distinctl,y lateral in its at- tachment. As it increases in size it may become pendulous (Fig. 731). It pushes forward the sub-hyoid muscles, and displaces the sterno - mastoid muscle and great ^'essels of the neck laterally, so that the vessels may be palpable at the posterior border of this muscle; it may distort or com- press the trachea and esophagus; and may cause symptoms from pressure on the sympathetic, recurrent, or superior laryngeal nerves. Rarely a goitre may grow down behind the ster- num, when its presence may be detected by percussion. Finally, a goitre may produce disturbance of the heart and circulation, either directly by pressure on the great vessels, or through interference with respira- tion; or in some instances from hyperthyroidism (p. 688). Intermit- tent pressure on the great vessels of the neck may produce giddiness and other evidences of disturbances in the intracranial circulation. In diffuse follicular and in imrenchymatous goitres the diagnosis Fig. 731. — Cystic goitre, of sixteen years' duration in a patient of thirty- seven years. Pennsylvania Hospital. SURGERY OF THE THYROU) dLANI) ()S7 rests on the soft, flabby consistency, palpation of the small but rather distinct lobules, and the vascularity. Early symptoms of hyper- thyroidism may be i)resent, and these usually will be increased by the administration of iodin. The (liffu,sc roUoUl goitre is relatively firm, the lobules are much larger, and some are quite hard; iodin causes no diminution in size. The dif use fibrous goitre is harder, and there are symptoms of hypothyroidism. In nodular colloid goitre (cystic goitre) the diagnosis often is made at a glance. The surface of the cyst is smooth, its form is oval or rounded, and its consistency elastic. The adenomatous goitre is recognized by its circumscribed character, and its soft and doughy feel. Treatment.— In many cases of difi"use goitre, judicious medical treat- ment, with attention to hygiene, will cause diminution or complete subsidence of the swelling. Operation is required only for cosmetic efl'ect, to relieve pressure symptoms, or to check progressive growth or a tendency toward hyperthyroidism. In most cases of nodular goitre operation is indicated at an early stage, for the same reasons which render its adoption advisable at a later stage in the diffuse form. This is particularly true of nodules undergoing degenerative changes, and especially of the nodular adenomatous form, since in this the ten- dency to malignant change is well marked. Finally, it may be stated in general terms, that any goitre of rapid growth or tender on pressure should be referred to the surgeon. The operation consists in excision of the affected lobe; or in case of one or two large nodules, in their enucleation; as the nodules usually are fairly well encapsulated the remainder of the gland may be left intact, to prevent development of symptoms of hypothyroidism. Enucleation is indicated especially where it is probable that very little healthy functionating gland tissue remains. In diffuse goitre it usually is found sufficient to excise one lobe, with a part of the isth- mus; the remaining lobe may then cease to cause symptoms. Should these continue, a part or whole of the second lobe may be removed subsequently. Kocher's incision is a transverse incision, slightly convex downward, crossing the neck over the prominence of the thyroid, from one sterno-mastoid muscle to the other. In operations on one lobe only, the incision need be only half as long. The flaps, including plat^'sma and fascia, are then dissected upward and down- ward, exposing the pre-thyroid muscles. These may be divided near the hyoid bone, if necessar>', thus preserving their nerve supply, and the tumor may then be dislocated into the wound. In all thyroid- ectomies, partial or complete, hemorrhage should be scrupulously avoided, by clamping and ligating veins as they are encountered, and securing the superior and inferior thyroid arteries of the affected lobe before its excision is begun. Both arteries should be secured close to, or after entry of their branches into the gland. This is especially important in case of the inferior thyroid, so as to avoid interference with the circulation of the inferior parathyroid glandule (p. 691). Then the capsule of the gland is split open along its lateral 688 SURGERY OF THE FACE, MOUTH, AND NECK aspect, and the lobe is removed, leaving part of it adherent to the posterior portion of the capsule, so as to avoid injury to the parathy- roid glandules and the recurrent laryngeal nerve. The occasional presence of a thyroidea ima artery should be remembered. The isthmus is clamped and is ligated, in the groove made by the clamp, before it is divided. Severed muscles are then sutured, and the wound is closed with ample drainage. Strumitis. — Inflammation of a goitrous thyroid is less unusual .than that of the normal gland. The diagnosis rarely is flifficult, and the treatment is the same as for corresponding forms of thyroiditis. Hypothyroidism. — In persons from whom the entire thyroid gland is removed there usually develops a condition of acquired cretinism, known as myxedema, or cachexia thyreopriva. The signs of this con- dition need not be detailed here. A knowledge of the condition is sufficient to warn the operator not to remove all the function- ating thyroid tissue. If this course has to be pursued in the eradi- cation of malignant disease, the patient should ingest daily a sufficient quantity of thyroid extract to keep the myxedematous symptoms in abeyance. Transplantation of thyroid tissue, from man and from some lower animals, has been tried in such cases, and in some instances with encouraging results. The portions of thyroid gland have been implanted subcutaneously, in the subserous tissues, in the splenic pulp, and in the bone marrow. In most cases, even if the graft functionates properly for a time, it eventually is absorbed, and myxedematous symptoms again develop. Hyperthyroidism {Exophthalmic Goitre, Graves's Disease (1835), Basedow's Disease (1840), Thyrotoxicosis). — Administration of thyroid extract in excess to normal persons causes the development of certain symptoms which are also present in some diseased states of the thyroid gland. These symptoms are the direct antithesis of those observed in myxedema. They may be grouped in four main categories: (1) Local changes in the thyroid. (2) General circulatory symptoms. (3) Nervous symptoms. (4) Metabolic changes. There should also be mentioned exophthalmos, which usually is present, but sometimes is not associated with other typical symptoms. The affection is much commoner in women than in men (about 6 to 1), and occurs usually between the ages of fifteen years and thirty- five years; it is less rare after thirty-five years than before puberty. It appears to be induced by physical or mental exhaustion, worry, anxiety, fright, fear, etc. Sometimes it develops very acutely; in others very rapidly, but not suddenly; at other times its onset is insidious. In the cases which develop rapidly, the goitre usually makes its first appearance at the time that the thyrotoxic symptoms develop; in the chronic cases, with slow onset, a goitre usually has been present for months or years before hyperthyroidism ensues. Local Changes. — The thyroid usually is enlarged symmetrically and diffusely. Its vascularity is increased, giving it a soft feel; but deep pressure detects a gland firmer than normal. Nodular goitre SURGERY OF THR THYUOUJ dLAND ()89 rarely is associated with tli\ ro-toxie s\ iiiptoins. The more acute the onset, the more marked are the local ehanj^es. In cases of long duration, especially when medical treatment has heen prolonged, the gland hecomcs smaller and firmer, hut tiie vascular phenomena may be demonstrated again after excitement. In some cases no local changes are ])ercej)til)le, and the diagnosis depends on other signs. Circulatory Symptoms. — Tachycardia is the most prominent symp- tom: the ])ulse is ahnormally frecjucnt, (piick, usually of high tension, and extremely irritable (A. K'ocherj. These changes may he acute in onset, or very gradually de\elop. Excitement always accentuates them. Nervous Symptoms. — Restlessness of mind and body is exceedingly characteristic. The patient inclines to be hysterical, and weeps with- out j)r()\ocation; there is insomnia; tremor, especially marked in the hands, tongue, and lips; and various psychoses may develop. Fig. 732. — -Exophthalmic goitre. Fig. 733. — Exophthalmic goitre. Same Duration seven year-s; twenty-eight patient as Fig. 732. Episcopal Hospital, years old. Has had seven children. Goitre has grown rapidly during the last year. No tachycardia or ner- vousness. Exophthalmos not noticed by patient. Episcopal Hospital. Metabolism. — In general terms, all metabolic activity is increased. The skin is warm and moist; the temperature slightly raised; the amount of urine increased; weight is lost, and in advanced stages emaciation may occur. Brown atrophy of the heart and degenerations of the other viscera develop eventually, and render recovery impossible. There is great weariness quite early in the disease. Frequent attacks of diarrhea may occur. Capillary hemorrhages are not infrequent. The blood-changes are said by Kocher to be characteristic, and almost pathognomonic: there is slight leukopenia, but marked increase in the actual and proportional number of lymphocytes, \vhich may out- number the neutrophile leukocytes; the red blood cells and hemoglobin remain unaltered. 44 690 SURGERY OF THE FACE, MOUTH, AND NECK Exophthalmos is not a necessary feature of hyperthyroidism. It may be present, and associated with a goitre, without any of the cir- culatory, nervous, or metaboHc symptoms which are characteristic of the disease (Fig. 732). Its pathogenesis is not understood. It may be absent when other symptoms of the disease are very pronounced. Diagnosis. — This depends on recognizing the circulatory, nervous, and metabolic symptoms which have been detailed above; and on the blood-changes, on which great stress is laid by Kocher. The existence of a palpable goitre and exophthalmos are confirmatory signs, but by no means necessary for a diagnosis. The histological diagnosis, as pointed out at p. 684, depends on the recognition of increase in the secreting surface of the gland, quite apart from other changes which may be present. Prognosis. — Theoretically, hyperthyroidism is a self-limited disease; but the disease may kill the patient before it burns itself out. In rare cases the thyrotoxic symptoms subside, perhaps aided by medical treatment, and those of hypothyroidism succeed. The thyroid thus may destroy itself by hypersecretion. But in most cases the disease grows progressively worse. The more acute its onset, the more rapid is its course. Acute exacerbations characterize some rather subacute cases. In these and in the hyperacute cases, death may occur in a paroxysm, with rapid cardiac exhaustion (delirium cordis), general edema, albuminuria, fever, dyspnea, etc. In other, more chronic,^ cases, death occurs from intercurrent maladies, such as influenza or tonsillitis; it may occur merely from administration of an anesthetic for operative purposes, since viscera damaged by the long continuance of intoxication cannot functionate under these additional demands. Treatment. — As the disease is due to intoxication from the thyroid gland, there are two logical remedies: one is removal of part of the gland, the other is the preparation and administration of an antitoxic serum. The latter has been tried by Beebe and Rogers, but not with the uniform success w^hich has attended operative treatment, and must be continued indefinitely as the cause of the symptoms is not removed. In the hyperacute cases usually no treatment is of use, and death occurs in a short time. In the subacute cases, in which the thyrotoxic symptoms and the goitre appear simultaneously, medical treatment should be tried before resort to operation, as by procuring absolute rest for mind and body it is possible to ameliorate the patient's condition. In most cases confinement to bed is imperative, in isola- tion. Local cold is of great value in quieting the tachycardia. Kocher thinks iodin internally is of much value. The bowels and kidneys must be looked to, and a milk diet may be beneficial. Belladonna or atropin, with an occasional course of bromides, are useful in controlling circulatory disturbances. If no improvement is evident within a couple of weeks, it is useless to pursue this treatment further, and operation should be undertaken, as it should even earlier if the patient continues to grow worse, and in the more chronic cases where it may be employed safely without such careful preparative treatment. SURGERY OF THE THYROID GLAND (391 The Parailit/rolds. — In all ()i)tTati()ns injury i)f the jjarathyroids should be avoided; for thou<;;h Shepherd attaches little importance to them, other surgeons of etpial or fjreater experience (Kocher, ('. H. Mayo, Crile, Halsted) entertain the greatest respect for their powers of good and evil. These little glands, of uncertain function, usually are four or more in iuunl)er; they are situated two on each side of the neck behind the thyroid gland, and separated from it by the posterior ])ortion of its capsule. The lower pair are in relation with the terminal branches of the inferior thyroid artery, and are the more constant in position. The upj)er parathyroids are supplied either from the superior thyroid artery or from communicating branches from the inferior thyroid. Removal or destruction of all the parathyroids is supposed to be the cause of post-operative tetany, which has been seen in a few cases. As it is impossible to identify the parathyroids except by histological examination (macroscopically they cannot be distinguished from lymph nodes), the only safe course is to keep clear of the site where they normally are found. This is best done in excisions by leaving the posterior portion of the capsule and, if necessary, a layer of thyroid tissue adherent to it. Operation. — In severe cases it is the custom first to diminish the thyrotoxic symptoms by ligating one or more of the arteries supplying the gland; and to proceed to partial excision within a week or ten days, before the favorable effect of the preliminary operation has passed away. In very acute cases the patient will be so much worried and excited by the anticipation of any operation, that Crile has adopted the ingenious plan of instituting a course of very strict pre-operative treatment, repeated every morning, and embodying the essential steps in preparation for operation, as if they in themselves consti- tuted the treatment. Every morning the patient's neck is washed as if for operation, and dressings are applied; every morning she inhales some essential oil, to simulate an anesthetic. Then some favorable morning, in the course of usual routine, a real anesthetic is given, and the operation is completed without the patient being aware of any change from the daily routine. In Kocher's hands, the mortality of operation in 200 severe cases was 4.5 per cent.; and there were S5 per cent, of cures. In cases with advanced visceral degenerations operation is useless. Ligation. — j\Iost surgeons follow Kocher in ligating one or both superior thyroid arteries. But Delore and Alamartine (1911) have pointed out that the circulation is much better controlled if the superior and inferior thyroids on the same side are ligated. Halsted (1913) now ligates both inferior thyroids. The sujjerior thyroid artery is exposed by a small transverse incision over the upper pole of the lateral lobe, which usually is palpable through the skin; the sterno- mastoid is drawn backward and the omo-hyoid forward, and the pole of the gland itself is ligated extracapsularly, in two places. This "polar ligation," introduced in 1909 by Jacobson and Stamm, and adopted by C. H. Mayo, is valuable as it does not interfere with the 692 SURGERY OF THE FACE, MOUTH, AND NECK blood-supply to the superior parathyroids, which would be jeopar- dized if the main trunk was ligated; and because it controls the veins and lymphatics and also destroys most of the vasodilator nerves entering the lateral lobe. This polar ligation thus becomes what Delore and Alamartine call an angeio-neurectomy. The inferior thyroid artery is best ligated at its origin from the thyroid axis, since it divides into numerous branches before entering the gland, and separate ligation of these is difficult and exposes the recurrent laryngeal nerve and inferior parathyroid to injury. The artery is exposed by an incision parallel to the clavicle at the posterior border of the sterno- mastoid; the anterior scalene muscle is located, and the thyroid axis found just to its median border. Thyroidectomy. — As in the case of simple goitre (p. 687) only one lateral lobe is to be removed. If symptoms persist, half of the remain- ing lobe may be removed at a second operation. Great care in hemo- stasis must be exercised, and the wound must be freely drained. Sympathectomy (Jaboulay, 1896). — Excision of both superior ganglia of the cervical sympathetic, effective in overcoming the exophthalmos, has been abandoned by most surgeons, because it has very little influ- ence on the other symptoms. Malignant Tumors of the thyroid are not very rare, especially in goitrous regions. Carcinoma is commoner than sarcoma; endothe- lioma also occurs. Clinically, the distinction is not of much impor- tance, since, as A. Kocher says, "By the time malignant goitre reveals its two chief characteristics it is too late for a radical cure." He adds that if the thyroid continues to enlarge after puberty, in spite of appropriate internal treatment, and in the case of any thyroid which begins to grow without any apparent cause after the thirty-fifth year of life, malignant change should be suspected. The two chief char- acteristics of these malignant tumors are irregular growth, and change in consistency. Instead of the nodules being more or less uniform in distribution and size, a few of them will begin to project to an abnormal degree beyond the others, and they will lose their elastic consistency and become firmer and more flesh-like. Pressure symptoms occur earlier than in benign enlargement, because of development of adhe- sions to surrounding structures. Spontaneous pain is not an early symptom, but occurs in malignant growths much sooner than in benign. Prognosis. — The prognosis is bad. Metastasis occurs early, and may be the first evidence of malignancy. In carcinoma, and even in histologically benign diffuse adenoma, metastasis to bones is frequent; and Shepherd has observed pulmonary invasion by carci- noma through the internal jugular veins. Treatment. — Very early extirpation is the only method that offers any hope of cure. Shepherd says he has completely excised over a dozen thyroids, and never save in one case (repeated operations for recurrence) has seen any evil effects attributable to injury of the para- thyroids though he has taken no care to preser^•e them. But the SURGERY OF THE ESOI'IIAGUS 003 j)r()j)hylactic julniinistratiou ot* j)arathyr()i(lin is rccommeiult'd, aiul tho use of thyroid extract may he necessary to prevent myxedema. Trac'heotomy may he necessary in tar nd\ancc(l in()i)eral)le cases; it may prove a difficult operation. SURGERY OF THE THYMUS GLAND. In some infants acute or chronic dyspnea is due to enlargement of tlie tliymus ghmd, which compresses the trachea. I'sually the enhirged gkmd may be detected by percussion, and its presence should be suspected when tracheotomy fails to relieve the dyspnea. Then the incision may be extended down to the episternal notch, when the thymus (much like an enlarged lymph node) will protrude from the anterior mediastinum, and may be drawn up into the neck. In some cases it has been sutured to the sterno-mastoid muscle to keep it from again becoming wedged in the thoracic opening, but it is better to enucleate it from its capsule and remove as much of it as is easily detachable. The wound should not be drained, for drainage implies infection, and this means death. If the respiratory obstruction is relieved in time, recovery follows. Olivier (1912) has studied the results of 42 thymectomies; of the 15 deaths, 7 w^ere not due to the operation, and 8 were attributed to the secondary tracheotomy. He concludes that subtotal, subcapsular thymectomy is the best treat- ment. SURGERY OF THE ESOPHAGUS. Foreign Bodies. — There are three points at which a foreign body is apt to be arrested: (1) At the level of the cricoid cartilage; (2) where the left bronchus crosses the esophagus; (3) at the cardiac orifice of the stomach. All sorts of things may be swallowed: chil- dren's playthings, false teeth, pieces of bone, and in the insane, even spoons, forks, etc. Large bodies usually are arrested in the pharynx, and often may be extracted with the finger. Bodies with sharp prongs may catch in the esophageal wall at any point, and much damage may be done by forcible attempts at extraction. The diagnosis depends on the history, which in infants and the insane may be very uncertain; on the presence of dysphagia; and on the results of examination with esophageal instruments and the .r-ray. It is important to make the diagnosis as soon as possible, before inflam- matory softening or perforation of the esophageal wall occurs. Do not postpone thorough examination until the next day, thinking the diagnosis will be easier then. It will not be. The esophagoscope should be employed whenever available, and if used early, before the mucous secretion is excessive, the foreign body usually can be seen. This is an instrument analogous to the bronchoscope and cystoscope. It is very much safer in skilled hands than the insertion of a bougie, but this may be the only instrument obtainable. 694 SURGERY OF THE FACE, MOUTH, AND NECK Treatment. — By means of an esophagoscope and the special instru- ments employed with it, one skilled in the use of such apparatus frequently will be able to extract the foreign body under the control of the eye. If this is not possible, the surgeon must employ the older and less satisfactory method of introducing an esophageal forceps, probang, or coin-catcher and thus endeavoring to remove the foreign body by the sense of touch. A general anesthetic is required. A coin usually lies transversely in the esophagus, and may be caught by a Fig. 734. — Forceps for removing foreign bodies from the esophagus. forceps whose blades open in this direction (Fig. 734). If the coin lies very far down in the esophagus the old fashioned "coin-catcher" (Fig. 735) may be more useful. Occasionally a lodged foreign body may be advantageously pushed on into the stomach. It is not safe to make violent or too prolonged efforts at extraction, especially when more than thirty-six hours have elapsed. When all reasonable efforts have failed, or at once if the nature of the impacted body forbids attempts at extraction through the mouth, the surgeon should Fig. 735.- -Esophageal instruments: 1, Olive tipped bougie; 2, horse-hair probang ; 3, coin-catcher; 4, esophageal forceps. resort to external esophagotomy if the foreign body is well above the cardiac orifice; if impacted at the latter site, extraction should be attempted by gastrotomy (p. 876). Under the best modern methods it might be possible to perform transpleural esophagotomy. External Esophagotomy. — Through an incision along the anterior border of the left sterno-mastoid, with division or downward dis- placement of the omo-hyoid, the esophagus is exposed behind the trachea and on the median side of the great vessels It should be freely SURGERY OF THE h'SOI'llACUS 095 separated from the surrounding tissues, and incised on a sound passed from the mouth, after pulling it up into the wound and isolating it with gauze. The foreign body is then extracted with finger or for- cei)s. The incision in the esophagus is tightly sutured with at least two rows of chromic gut sutures, and a drainage tube is passed down to the site of suture, and is not removed for a week. The remainder of the wound is closed in layers. No food should be swallowed for a week or ten days; rectal feeding should be employed, especially saline solution as in peritonitis, but in the case of very weak patients food may be introduced into the stomach by a stomach tube. The prog- nosis is good if the foreign body has been removed within the first thirty-six hours. Stricture of the Esophagus usually results from lye burns, and is especially frequent in small children who drink a cupful of the nice white Huid, mistaking it for milk. It may occur also in adults, from ingestion of corrosive poisons. Symptoms of stricture may not develop for several months after the accident. Sometimes they appear rather suddenly, but usually there is a gradual but progressive increase in dysphagia, at first for solids, then for liquids, and finally regurgitation occurs through the nostrils as soon as food is swallowed. In time a pouch may form, and then regurgitation may not occur for half an hour or more after food is ingested. Any inflammatory attack is apt to produce complete obstruction. Weight is constantly lost, and emaciation may become extreme. There is a decided tendency to bronchial and pulmonary disease, owing to regurgitation of decaying food, and death may occur from such intercurrent malady. Diagnosis. — The diagnosis is made from the history of the accident, from the symptoms, and from examination of the esophagus. This should be done by the esophagoscope; but if this is not available, an olive-tipped bougie (Fig. 735) may be passed ver}' gently and cautiously; and the existence of a stricture and its site may be thus determined. The x-ray will detect the existence of a pouch if this is filled with bismuth gruel. Treatment. — 1. If the stricture is easily permeable to liquid food, it usually will be possible to secure passage of a bougie, especially if this is done under control of vision through the esophagoscope. Many strictures impermeable to blind instrumentation are not imper- meable with esophagoscopy. The danger of perforation, especially if there is a thin walled pouch, always should be kept in mind. Such an accident generally results fatally in a few days from septic pneu- monia or mediastinitis. If a bougie can be passed, gradual dilatation often is possible, as in the case of permeable urethral stricture; but hazardous as is the employment of any force in urethral instrumenta- tion, it is absolutely harmless compared to its use in esophageal work. The safest esophageal sound, when one is used without the esophago- scope, is the olive-tipped bougie, but it is relatively safe only because of its size. The smaller the stricture, the more flexible should be the instrument. Gradual dilatation may be aided by internal esopha- 096 SURGERY OF THE FACE, MOUTH, AND NECK gotomy througli the esophagoscope, the edge of the stricture being divided under full view. Subsequent dilatation always should be conducted under control of esophagoscopy. 2. If the stricture is impermeable to instruments, the treatment depends somewhat upon the amount of nourishment the patient can take. If sufficient nourishment is taken to maintain weight, various expedients may be tried to get through the stricture. The patient may be made to swallow a silver l)all (Abercrombie, 1830) or per- forated shot (Socin, 1889) attached to a string; after resting on the stricture for some hours these may pass through, and thus from day to day larger balls may be used, until a bougie can be passed. These methods are not more effective than esophagoscopic instrumentation, but may be tried when this is not available. External esophagotomy rarely can be recommended, e\en when the upper end of the stricture is accessible through the neck. It is not likely that this method will be successful when esophagoscopy has failed, and it cannot be known that the stricture does not extend all the way down to the cardiac orifice. If weight is being lost, it is useless to postpone a resort to gastrostomy (p. 877). When the stomach is opened, attempts may be made to pass an instrument through the stricture from below, and these occasionally are successful. But if the patient is very weak it is better not to prolong the operation, but merely to establish an opening in the stomach as rapidly as possible. Stamm's or Senn's method is the best for these cases. It usually happens that the stric- ture becomes permeable after the esophagus has had a rest for some weeks, while food is being introduced through the gastric fistula. This is analogous to the usual course of impermeable urethral stric- tures after the performance of Cock's operation (p. 1026). When the stricture becomes permeable, a string may be passed through it from the mouth; then by extracting the other end through the gastric fistula, the stricture may be cut by a sawing motion, while the esopha- gus is kept taut to prevent damage to its walls (Abbe's method, 1893) ; or the surgeon may adopt von Hacker's method (1894) of retrograde dilatation by drawing through the stricture gradually increasing sizes of rubber tubing, at intervals of a few davs ("Sondierung ohne Ende"). 3. If the stricture remains impermeable even after gastrostomy, there are still several plans of treatment which may be adopted. Maffei (1906) in two cases successfully exposed the esophagus by the transpleural route, and found that the stricture became permeable as soon as he had released the peri-esophageal adhesions ; the esophagus was not opened at all. Roux (1907) and Herzen (1908) have formed an artificial esophagus by transplanting beneath the skin of the sternum a loop of the upper jejunum, excluded from the intestinal tract. This is to be attached above to the cervical esophagus, and below to the stomach. Herzen's name for this delicate procedure, which is completed in several sittings, is "ante-thoracic esophago- jejuno-gastrostomy." Willy Meyer (1913) has followed Jianu and HVRCERY OF THE ESOl'llAGUS ()07 Uocpkc ill iitiliziii»i; a llii]> t'roiii the <:;r('at('r ciirNiitiin' ol' (he stoiiiacli, to ('(Histriict a now ])rc-stt'riial (•s()|)lia<,nis. Congenital Imperforation of the Esophagus is a rare iiialtorination ill wliicli tlif gastric end of the eso]jlia^ns usually empties into the bronchus, and the pharyngeal end terminates in a l)lind pouch. Tiie hal)\' sutlers from recurring attacks of sutt'ocation due to regurgi- tation of gastric contents into the air passages; food swallowed is at once regurgitatefl. The best treatment is jjerforinance of jejiino.S'toniy (]). 878), for the purpose of introducing nourishment, as advised by Demoulin (1904). Should the infant survive (which is unusual) treatment as for impermeable stricture of the esophagus should be attcm])tcd later. Diverticula of the Esophagus may be congenital or acquired. The ac(|uirc(l diverticula are due either to traction from without (usually from adhesions to bronchial lymph nodes, etc.), or to pressure from within. The irariion diverticula rarely produce symi)toms, as their lumen is oblique or horizontal and the orifice is directed down- ward (Zenker, 1878); food is not apt to collect in them, and often they are found unexpectedly at autopsy. But occasionally during life perforation occurs. Pressure diverticula, well studied by Halstead in 1904, constantly produce symptoms during life, from accumula- tion and regurgitation of food. Sometimes during meals a palpable tumor appears in the left side of the neck, and can be emptied by pressure. Often the earlier part of a meal will be swallowed more easily than the latter part, because gradual filling of the pouch causes obstruction of the esophagus. The pouch is found most often to spring from the posterior wall of the esophagus in the median line, just below the pharynx. A bougie sometimes will be arrested in the pouch, and sometimes will pass on into the stomach, and thus the condition may simulate a spasmodic stricture. But if one bougie is arrested in the pouch, it may be possible to pass another alongside of it into the stomach. The diagnosis is aided by esophagoscopy and by the use of the x-ray after filling the pouch wuth bismuth gruel. Treatment. — If the diverticulum is accessible from the neck, it should be exposed from the left side, and excised. The stump is treated as the appendix stump (p. 857), and the wound treated as in external esophagotomy (p. G94). Dilatation of the Esophagus, as a whole, usually is secondary to what has been described as cardiospasm, w^hich is now believed to be not a spastic condition of the cardiac orifice of the stomach, but of the esophagus just above the cardia. The cause of the "cardiospasm" has not always been determined, but in some cases gross esophageal lesions (ulcer, carcinoma, etc.) have been found. Symptoms. — The symptoms are those of slowly oncoming and never entirely complete obstruction to food. In the early stages there is a feeling of fulness after eating, with an uneasy sensation in the epigastrium or behind the sternum; the patient eats very slowly, and requires much liquid to wash the food down; final entrance of 698 SURGERY OF THE FACE, MOUTH, AND NECK food to the stomach may be accomphshed only after the patient has retired to a corner and urged the food down by deep breathing, gulp- ing, or curious contortions of the arms and body. Later, regurgitation occurs immediately after swallowing; but when full dilatation has developed food may be retained for several hours. The regurgitated food is not sour, as it would be if vomited after lying in the stomach. Diagnosis. — Diagnosis is based on the symptoms, and on the exclu- sion of organic stricture by esophagoscopy or by passage of a bougie. A bougie may be arrested near the cardiac orifice, but usually passes through after temporary arrest. A skiagraph, made after ingestion of bismuth gruel, also is helpful. Treatment. — The most satisfactory treatment is forcible divulsion of the cardia. This can be done by instruments passed by mouth, as in the methods of Sippy and of Plummer. The apparatus consists of a rubber bag about 10 cm. long, encased in a silk bag which limits the possible distention to a circumference of 15 cm. Dilatation is produced by an air-pump. The treatment usually must be repeated several times before complete relief is secured. No anesthetic is necessary. In some cases divulsion of the cardia may be done after gastrostomy. Carcinoma. — Carcinoma is the most frequent disease of the esoph- agus. It occurs oftenest in males, in the decline of life. About 50 per cent, of cases are near the cardia, 40 per cent, at the bifurcation of the trachea, and only 10 per cent, at the cricoid cartilage. It probably often develops in an ulcer or erosion. Its onset is insidious, but when once symptoms develop, they progress rapidly. The chief characteristic is increasing difficulty in deglutition, for which no cause can be found in the patient's clinical history. Syphilitic stricture is rare but must be excluded. The diagnosis from aortic aneurysm often is exceedingly difficult. In carcinoma very early and great enlargement of the bronchial lymph nodes may occur; there often are pressure palsies of the recurrent laryngeal or sympathetic nerves; and dyspnea may exist. Referred pain is common, and erosion of the vertebrae and even paraplegia may develop before symptoms of esophageal obstruction are marked. Pulmonary complications are frequent. Passage of a bougie may provoke hemorrhage. Esopha- goscopy is important. The prognosis is very bad. Death u.sually occurs in a year from the date of diagnosis. Treatment. — When thoracic surgery becomes better developed, and especially by the use of anesthesia by intratracheal insufflation, it will be possible to explore the seat of disease, with the hope of doing a radical operation. This has been accomplished once successfully, by Torek (1913). In most cases only the palliative operation of gas- trostomy is successful, but this should not be employed so long as liquids can be swallowed. Whenever possible, before this operation is done, the intestinal tract should be cleared of the masses of stagnant feces usually present. CHAPTER XX. SURGERY OF THE BREAST, THE CHEST WALL, THE LUNGS, AND THE DIAFHI^AGM. SURGERY OF THE BREAST. Congenital Anomalies. — The only one of these that is of much surgical interest is the existence of supernumerary breasts, a con- dition known as poJymastia. Either sex may be affected, but it is said to be slightly more common in males. The extra glands may be situated almost in any part of the trunk, most often near the axilla or groin (Fig. 730), or in a line joining these two sites. The accessory glands may be of various sizes. Sometimes only a supernumerary nipple is present (polythelia), (Fig. 737), and sometimes a mass of mammary tissue without a nipple exists in the subcutaneous tissues. In men this resembles a lipoma; but in women its true nature is revealed by its increase in size during menstruation, or pregnancy, or lactation. Any supernumerary mamma which causes annoyance should be excised. ll"'' 1 ^^^^H 9 ^^B||C Fig. 736. — Supernumerary mamma (or lipoma?) in adult male. Since puberty has had this mass which at times used to discharge a little whitish fluid. Note the nipple- like projection, but absence of pigmentation. Episcopal Hospital. Affections of the Nipple. — Sometimes a nipple fails to develop properly, especially where tight underclothing is constantly worn. During pregnancy care should be taken to favor its development by drawing it out, gently; and it should be further prepared for suckling by frequent cleansing and application of astringent washes, of which none is better than dilute alcohol. During lactation, roo SURGERY OF THE BREAST not only should the condition of the infant's mouth be watched, but the nii)ple should be washed with warm water and castile soap before and after suckling, and if any tendency to irritation exists it should be dustcfl with boric acid or borated talcum powder after cleansing after each act of nursing. Fissures and excoriatiuris of the nipple, which are extremely painful and interfere with suckling, should be treated by unremit- ting attention to cleanliness. The use of a nipple shield or breast pump, so as to prevent direct contact of the child's mouth, is necessary, and in most cases the act of suckling must be discontinued tempor- arily. The excoriations and fissures, after gentle cleansing, should be painted with dilute tincture of iodin (1 part to 5 of water), or a weak glycerite of tannin, and then dusted with boric acid powder. The use of ointments is injurious. Acute Mastitis. — Though in- flammation of the breast occa- sonally develops in the newborn, and in boys and girls at puberty, it occurs oftenest in nursing women, being in most cases an ascending infection from the nipple by way of the ducts or the lymphatics. It is most frequent in primiparse, especially in those with poorly developed nipples, which have received insufficient attention during pregnancy. It occurs most often within a few days of delivery, or not until the end of lactation. Acute mastitis is characterized by the usual signs of inflammation, which are confined in almost all instances to one or more lobes of the gland. Diffuse inflammation is rare. The regions affected feel tough and doughy, and tenderness is not very marked. The skin is unaltered and moves freely over the breast. There is a heavy feel- ing, with dull pain, and occasionally shooting pains. In a puerperal woman this stage is described as "caked breast," because of the accu- mulation and inspissation of the milk owing to obstruction of the galactophorous ducts b}' the inflammatory changes. Treatment. — Treatment consists in attention to the nipple, which may be fissured or excoriated, and to the patient's general health. The child should not be allowed to suckle from the affected breast until resolution is complete. Daily light massage of the area affected usually is efficacious in overcoming the stagnation and promoting resolution without suppuration. Some ointment with lanolin as a basis should be used in connection with the massage. In the Fig. 737. — Polythelia; a supernunifrary nipple near right nipple. Orthopgedic Hos- pital. MAMMARY ABSCESS 701 intervals the breast should he covered with heiladoiina and mercury or other sorhet'acient ointment, and well supported with a compressory handa;i;e or hinder. Meantime a breast pump nnist l)e emi)loyed. Another valuable aid in resolution is passive hyperemia, according to Bier's method, with a cupping glass applied over the nipple, as originally introduced by (Miassaignac. Mammary Abscess. — Mammary abscess usually develops as a sequel of stagnation mastitis (caked breast). The area affected becomes more tender; dusky redness appears in the skin; this becomes adherent to the deeper structures; and the abscess is ready to be oi)ene(l (Fig. 7.SS). Before this occurs, however, destruction of the mannnary tissue may be very extensive, and it is very im- portant to recognize the onset of suppuration as early as pos- sible. The fluid expressed from the nipple by massage, in the stage of caked breast, should be collected from time to time on gauze. The milk will be ab- sorbed; but if there is any pus in the fluid, it will remain on the surface of the gauze and stain it yellow. This is known as Budin's sign. As soon as suppuration [is suspected, the inflamed area should be incised. This incision should be made directly over the area affected, and in a line radiating from the nipple, so as to injure as few of the milk ducts as possible and thus decrease the chance of a lacteal fistula developing. The earlier and more freely this incision is made, the less danger there is of the pus burrowing among the glandular tissue. If delayed, various pockets of pus will be found, and these will have to be broken open by the finger to ensure free drainage. Tube drainage is desirable until the discharge of pus ceases. An abundant dressing of hot moist gauze (soaked in boric acid or normal saline solution) is required to absorb the discharge. After drainage is discontinued the wound closes rapidly in most cases, if incision has been made early enough; if it has been delayed or not sufficiently free, secondary abscesses may form. Very rarely, when the breast is riddled with abscesses and discharging sinuses, amputa- tion is required. Chronic mammary abscess is not very rare; it may be subacute or frankly chronic. The former usually arises during lactation, as the result of an unresolved stagnation mastitis; or after an imperfectly Fig. 738. — Abscess of left breast in a primipara. Age twenty years, nursing a baby three months old. Duration of mastitis ten days. Incised and drained by tube; in nine days only a granulating sur- face remained. Episcopal Hospital. 702 SURGERY OF THE BREAST drained acute abscess. Those which develop independently of lactation are much more unusual, and may be due to suppuration in a hematoma (from trauma), or to excoriations, patches of eczema, etc., on the nipple or in the inframammary fold. The .symptoms are those of chronic mastitis (see below), but the yhysical signs resemble more those of a neoplasm (p. 711), and the diagnosis, which often is impossible, rests on the history of the case, and the detection of some source of infection. Treatment: Exploratory incision, best by the submammary incision (p. 711), usually is necessary for diagnosis; and the abscess wall which often is thick and indurated, should then be removed in entirety. Submammary Abscess. — Suppuration may occur in the cellular tissue between the pectoral muscle and the breast. Usually this is caused by an abscess in a deep lying lobe of the mammary gland, where pointing occurs tlirough the deep layer of superficial fascia in which the gland lies, instead of tlirough the overlying skin; indeed, prolongations of the gland may extend normally into the retro- mammary space. In a few cases, however, submammary abscess is secondary to axillary lymphadenitis or to diseases of the pleura, caries of the ribs, etc., which usually are tuberculous in nature. The diagnosis of submammary abscess is not always easy; the gland is prominent, raised away from the chest by the suppuration beneath ; but owing to the deep seat of the suppuration the ordinary physical signs of an abscess may not be present. The abscess may simulate a small hard tumor, especially as axillary adenitis often is present. Treatment consists in evacuation of the pus by a curved incision beneath the lireast, with free drainage until the discharge ceases. Subpectoral Abscess. — See p. 730. Chronic Mastitis. — In addition to the acute infectious mastitis, already described as most frequent in puerperal women, there occurs a form of circumscribed subacute or chronic mastitis, probably also infectious in origin, in women at almost any age, but usually in those between twenty and thirty, or in those approaching the menopause, and among the unmarried nearly as frequently as in those who have borne children. They come to the surgeon complaining of a painful and tender area in the breast, about which they not infrequently seem unduly alarmed. Examination shows slight or no enlargement of the breast, and palpation of the gland with the hand, pressing it flat against the chest wall, makes it clear that there is no tumor present. If the gland is examined between the thumb and fingers, one or more irregularly-shaped, ill defined masses may be felt; these usually seem to radiate from the nipple, and undoubtedly are in the glandular tissue. The overlying skin is unaltered, and the breast moves freely upon the chest wall. The mass may be exquisitely tender, and the seat of shooting or neuralgic pains. The overlying skin may be highly hyperesthetic. To such a condition in neurotic women, the term inastodynia or neuralgia of the breast has been applied. This is the " irritable tumor of the breast" of Sir Astley Cooper (1829), GALACTOCELE 703 thou«,fli it is also i)()ssihlr that sucli a coiulition iiiif^lit hv caused l)y a false neuroma (p. 293) as iu other ])orti()ns of the body. Pain referred to the breast in eases of intereostal neuralgia should not l)e confused with true mastodynia. In most ciuses of luaModynia both hreasia are affected, but only one out of a number of such lumps may give symptoms. They may produce symptoms during menstruation or pregnancy, and not at other times. The cause of these changes is obscure, and the subject is not much clarified by the various hypotheses which have been advanced. If the woman has borne children, the natural assumption is that these masses are the result of clianges occurring during lactation; they may be the remains of an area of stagnation mastitis (caked breast) which was so sHght as to have been overlooked at the time. In virgins, it may be assumed that the breast has been subject to forgotten trauma; or that its condition is connected with some functional derangement of the pelvic organs. The pathological anatomy of the condition is practically unknown, as operation has been undertaken very seldom. Lecene (1911) examined a fragment of tissue from such a specimen, and found lesions which corresponded to a functional hypertrophy of the acini, w^ith lymphatic stasis, and slight degree of congestion; he concluded that they were trophic or vasomotor in origin, and in no way truly inflammatory. The clinical course of the disease is various. Usually the symptoms subside under conservative treatment, and the masses do not enlarge or give any other evidence of their presence; in many cases they almost disappear. In some cases, however, a cystic transformation supervenes, the pathogenesis of wdiich is uncertain; probably it is neoplastic in character, and not due to inflammatory compression of the gland ducts (p. 712). Treatment. — Firm support, by bandaging or binder, or even by adhesive plaster strapping, should be provided, unless the tenderness is so excessive as to render this impossible. Belladonna and mercury, compound iodin or ichthyol ointment, applied to the breast, leaving the nipple uncovered, is useful in relieving tenderness. When tender- ness sul3sides, gentle massage should be given. The condition of the pelvic organs should be determined, and suitable treatment insti- tuted. Tonics, good food, and general hygienic measures should not be neglected. In addition to this circumscribed form of chronic mastitis, some writers recognize a diffuse chronic mastitis. I have discussed this subject at p. 709. Galactocele. — Closely related pathologically with chronic mastitis is the condition described as galactocele, formerly considered a retention cyst of the breast. The cyst wall, however, is not composed of secreting cells, but is formed by a condensation of surrounding connective tissues. Lecene (1911) holds that it is merely a chronic abscess into which milk ducts have opened secondarily; others, with 704 SURGERY OF THE BREAST less probability as it seems to me, contend that the primary con- dition was dilatation of the lactiferous tubules, and that the cyst is formed by their rupture into the surrounding tissues. Galactocele is quite rare, and occurs most often during lactation. A small lump forms quite suddenly; usually it is in the region of the areola, but may be more deeply seated. Sometimes several cysts exist. The mass is not tender or painful, feels semi-cystic, and is quite movable beneath the skin and on the underlying pectoral fascia. In many cases pressure on the swelling causes milk to exude from the nipple, and the cyst may thus be emptied. In other cases its contents become inspissated, and resemble butter or cheese, when there may be pitting on pressure, which is a very characteristic sign. Lacteal calculi have been described in some of these cases, but modern writers consider the reports apocryphal. Treatment. — A galactocele should be excised, and the wound sutured. Incision, followed by packing, is followed by tedious cure, and the cicatrix is more conspicuous. Tuberculosis of the Breast is a rare affection. It occurs almost solely in women from thirty to fifty years of age, usually those who have borne children. The infection may be an ascending one from the nipple, by way of the ducts or lymphatics; may be hematogenous; or may arise by extension from an adjacent focus in the ribs, sub- mammary lymphatics, or pleura. ]\Iany scattered nodules may be found, or one or two large masses. The tendency toward the forma- tion of cold abscess and toward spontaneous fistulization is more common in the latter form. Until this stage is reached the diagnosis is nearly impossible clinically, and even after these developments it is not always easy. The axillary lymphatics usually are enlarged. If secondary infection follows fistulization, the general health rapidly deteriorates. Treatment. — The only satisfactory treatment is amputation of the breast, and extirpation of the axillary lymphatics. The operation resembles that for carcinoma, but it is not necessary to remove the pectoral muscles unless they are manifestly diseased. Syphilis. — Syphilis may affect the skin over the breast, or the mammary gland itself. A chancre presents the same characters here as elsewhere; it occurs almost exclusively in women who act as wet-nurses to foundlings or other infants with congenital syphilis; the lesions may be multiple and often both breasts are affected. Prophylaxis usually is possible, and a syphilitic child never should be nursed by another than its own mother, who is immune to infection in this way^ according to Colles's law (p. 998). Secondary lesions of syphilis, especially mucous yatches, often may be found in the sub- mammary fold when not visible elsewhere. Sometimes in this stage of syphilis the mammary glands become swollen and painful, the condition being known as diffuse syphilitic mastitis. Gumma is the most frequent lesion of syphilis which affects the glandular tissue of the breast. It is quite rare, however, and is difficult to distinguish TUMORS OF Tilt: BREAST 705 from sonic hciiij^n tumors imlt'ss a distinct history ot" sypliiiis can be obtained, or the Wasscrmann test is positive, or when the bene- ficial cfVcct of antisyphiiitic treatment becomes apparent. Fortunately the iodides are \-er\ rapidly curative. Tumors of the Breast. — The subject of tumors of the mammary f,dan pericanalicular \ (b) Periductal myxoma (c) Periductal sarcoma j^ 12 per cent. 2. Cyst-adenoma, 2.4 per cent. (a) Fibro-cyst adenoma (b) Papillary-cystadenoma .3. Simple Adenoma j 4. Lipoma | 5. Angeioma [ 1 per cent. 6. Endothelioma 7. Enchondroma Malignant Tumors 1. Sarcoma, 1 per cent. 2. Carcinoma, 70 per cent. (a) Adenocarcinoma (6) Solid-celled Carcinoma 1. Scirrhous Carcinoma c 71 per cent. 2. Carcinoma Simplex 3. Medullary Carcinoma (c) Paget 's Disease of the Nipple (d) Carcinomatous Cyst Before discussing blastomas, or tumors proper, it is necessary to say something of certain blastoniatoid conditions Avhich occur in the breast. The general characters of these conditions were discussed in Chapter IV. In the mammary gland there occur lesions the true nature of which is still in much dispute. As to one condition especially, while it may be said that surgeons acknowledge its existence and are agreed on 45 706 SURGERY OF THE BREAST its clinical features; and while pathologists agree on the histological picture; yet the former cannot agree on a name which they consider descriptive, and the latter cannot agree on the interpretation of what they see under the microscope. This condition is known in some quarters by the name "chronic cystic mastitis." Another condition the classification of which is disputed, is described as ''idiopathic hypertrophy" of the breasts. Now when one looks at the classification of tumors given above, he sees that under the benign growths the two main types, which are fibro-epithelial in character, are (1) Fibro-adenoma, and (2) Cystadenoma. Were he to look around for blastomatoid conditions in his patients corresponding to these tumors, he would find that such conditions actually occur; and it would be a matter of surprise that no one had previously recognized that idiopathic hypertrophy of the breasts corresponds to a fibro-adenomatosis, and that chronic cystic mastitis corresponds to a cystadenomatosis. Let us look then at these two conditions more narrowly, and see what they are: Fibro-adenomatosis. — Diffuse or "idiopathic hypertrophy" of the breasts may appear first during pregnancy; but the disease in most cases affects virgins soon after the age of puberty. Albert (1910) has collected 18 cases of the former and 52 of the latter variety. It is doubtful whether the conditions are pathologically the same: in the cases which develop during pregnancy the glandular elements are markedly increased, whereas in the virginal form it is a pure fibromatous over-growth, the undeveloped glandular elements being practically unchanged. This difference may be due merely to the undeveloped condition of the virgin breast. Both breasts are enlarged in almost all cases (62 out of 70 cases collected by Albert), and they may reach an immense size. In Durs- ton's historic case, recorded in 1669, the weight of one breast, removed postmortem, was 64 pounds. Seldom, however, does the weight exceed 8 to 12 pounds. There are no symptoms other than dis- comfort from the size and weight, but the breasts may increase and decrease slightly in size from time to time. The form which arises during pregnancy sometimes subsides spontaneously when the pregnancy and lactation are ended; but the virginal form progres- sively increases. The growth is slow, and the disease extends over many years. Ver\' rapid enlargement of one breast alone, though it bear the character of a simple hypertrophy, always should rouse suspicion of malignancy, especially sarcoma. Treatment. — Treatment of the condition which arises during preg- nancy always should be palliative; this consists in the recumbent position, with elevation and compression of the breasts; the use of sorbefacient ointments locally; the internal administration of potas- sium iodide or thyroid extract ; repeated catharsis, and a dry diet. If no improvement is noted after pregnancy has terminated, and in the virginal cases as soon as the diagnosis is assured, one of the breasts should be amputated. In a few cases the remaining breast has then ( ' VST A DENOMA TOSIS 71)7 somewhat (l('(Tcas(>(l in size. If it docs not, it should he removed sul)se((ueiitl\'. Cystadenomatosis or Abnormal Involution of the Breast. In \SS'A Uechis (k'scrihed in detail a "cystic disease of the breast," wjiich he had studied first over twenty years before, and which had been recognized by F. Kcinig (1kin i> clo-cd w ith ])ruvision for drainage. 2. Cystadenomatous Tumors. — These seem to represent a later development of the fibro-adenomatous tumors just described; and as nearly all growths in the breast at the present day are removed soon after their presence is discovered, it results that cystadenomatous tumors are much more rare now than fifty or one hundred years ago. At that time the curious combination of fibrous and epithelial pro- liferation, resulting in solid (perhaps sarcomatous) tumors filled with cysts, was productive of great confusion as regards nomenclature. This class of tumor was described by Astley Cooper as hydatid disease of the breast; Brodie called it sero-cystic sarcoma; Paget named them proliferous mammary cysts; and Johannes Miiller used- the term cysto-sarcoma phyllodes, both the latter observers laying special stress on the occurrence of intracystic papillary out-gro^\i:hs To the present day the French call it adeno-sarcoma. The grovslh consists, in fact, of a cystic tumor, with a more or less abundant fibrous stroma — a fibrocysiadenoma. The cysts are of various sizes, usually some of them quite large. Their lining membrane may be quite smooth, as if from pressure atrophy. Almost invariably from one or more areas of the cyst wall, papillomatous growths project — papillary cystadenoma. These intracystic growths have a solid core of fibrous tissue, and they may completely fill the cyst and even cause its distention. It seems as if the proliferation of the stroma had converted the semi-circular chinks or slits of the intracanalicular fibroma into actual cysts formed by the pressure of papillary out -growths into the duct lumen. This impression is con- firmed by the fact that the papillomas are covered with cells which present the characteristics of ductal rather than of acinal epithelium. The small amount of fluid which the cysts contain may be colorless, slightly tinged with yellow or green, but usually is brownish or hem- orrhagic in nature. Symptoms and Clinical Course. — These tumors occur in older women than do the fibro-adenomatous gro"uths. The average age in Warren's patients was fifty-two years. Indeed, in most cases where cysts are found in the mammary gland it is an indication that this organ has reached its full maturity before the tumor began to grow. Cyst- adenoma grows more rapidly than the solid benign tumors, and if not removed, may reach a large size. The growth is situated in the central part of the breast, beneath the nipple or areola, and at first presents much the same features as the fibro-adenoma. In the course of a few years, however, the presence of cj^sts usually may be sus- pected from the lobulated nature of the tumor, and sometimes from distinct fluctuation. But the latter rarely occurs, since the cysts are apt to be filled with the papillary out-growths, which give them a solid feel. The overlying skin is not altered, the axillary nodes SARCOMA 713 arc not enlar<;e(l, and seldom is the f^eiu'ral health aH'eeted. Very often there is a hloody (hseharj^e from the nipple. In \ery advanced cases the skin overix inVS CARCINOMA 715 liard and tliickt'iu'd inaririns so characteristic of the commoner types of carcinoma, and ha\ in<,' its surface not depressed but rather ele- vated above the surrounding^ skin. Rarely does this growth long pre- serve the relatively benign character of an adeno-carcinoma; it soon lirt)liferates in an atypical manner like the solid-celled carcinoma. The latter, which is the usual form of carcinoma seen in the breast, arises in an atypical proliferation of the ei)ithclial cells lining the acini of the gland, and thus is distinguished from the rarer and less malignant duct-cancer by the term acinous carcinoma. Fig 740.— Carcinoma simplex of both breasts, age sixty-six years. Growth in left breast for five years, ulcerated five months; large sloughmg ulcer; axillary nodes palpable. Growth in right breast for two years: skin red and adherent; nippe retracted ; axillary nodes palpable. Palliative amputation of both breasts in October, 1909 with prolonged after-treatment by x-rays. (Dr. Thos. S. Stewart.) In September 1911, a metastatic growth appeared in right thigh. In August, 1913, mediastinal and pulmonary metastases but no local recurrence. In January, 1914, feeble, but little discomfort. Episcopal Hospital. The microscopical features of adeno-carcinoma and solid-celled carcinoma were considered at (p. 125). Clinically, the usual type of mammary carcinoma, that classed as solid-celled, is en- countered in tlu-ee varieties dependent upon the relative amount of stroma present: Scirrhous Carcinoma, in which stroma is very abundant and cellular elements scanty; Carcinoma Simplex, in which stroma and epithelial elements exist in equal amount; and Medullary Carcinoma, in which the epithelial elements are very abundant and the stroma is scanty. The clinical features of these three forms may now be briefly considered. Scirrhous Carcinoma, or simply Scirrhus, is the most frequent form of mammary cancer. Owing to the abundance of the stroma the tumor is quite hard; it seems as if the surrounding tissues were endeavoring to stifle the growth of the epithelial elements. On section the tumor is found to be absolutely continuous with the surrounding tissues; there is not the slightest indication of a capsule; it is impossible to remove the tumor from the gland. It is hard. 710 SURGERY OF THE BREAST and creaks when cut by the knife. Usually both the cut surfaces are found to be concave; it is as if the tumor was too small for the tissues in which it grew, and tended to contract further at the first opportu- nity. The surface of the section often has been likened to that of an unripe pear: it is pale and shiny, grayish white at first, but becomes pinkish on exposure to the air. Usually there are yellow dots scat- tered over the surface of the tumor; these are either spots of fatty degeneration, or areas of fatty tissues not yet strangulated by the fibrous stroma. On scraping the section with the knife, "cancer- juice" is produced; but this is no longer regarded as particularly characteristic of carcinoma. Symptoms and Clinical Course. — The patient finds a lump in her breast, but rarely are there any subjective symptoms. There may be occasional lancinating pains, but the tumor is not tender, a fact which distinguishes it from all inflammatory swellings. This lump in most cases lies in the per- iphery of the mammary gland, not near the nipple; and is found oftenest in the upper outer quadrant. It is hard, but not definitely outlined, when felt between the thumb and fingers; and it is still pal- pable as a dense nodule when the breast is pressed by the palm of the hand flat against the patient's chest. This dis- tinguishes it from non-neoplas- tic thickenings of the mammary gland. Owing to the abundance of the fibrous stroma and its tendency to contract, the size of the breast usually is dimin- ished in cases of scirrhus; when this contraction is extreme, the condition is named atrophic or withering scirrhus (Fig. 741). An early and valuable sign due to this contracting tendency has been pointed out by Halsted: this is limitatio7i of the excursions on the chest wall of the affected mamma as compared with the normal gland. If the breast is pulled from side to side, and up and down, even in the case of a small, deeply seated, and almost impalpable nodule, it will be found that the excursions of the affected breast are diminished, especially in a direction away from the axilla. The cancer cells extend along planes of fascia in all directions, and the abundant fibrous stroma follows them up, as if in the endeavor to strangle them by its contraction. This extension and subsequent contraction limits the excursions of the breast, pulls the nipple down into the gland {retraction of the nipple), and, tlirough the ligamenta suspensoria of Sir Astley Cooper, causes the typical Fig. 741. — Atrophic or withering scirrhus of breast. Age seventy-five years; growth noticed only a little over a year ago; ulcer- ated for six months. Has had no treatment, and the growth is now adherent to the ribs and inoperable. Episcopal Hospital. > < ^ a a>'0 a a to m CO 03 ^:S 3 o +i S' 3 03 _g 13 O ■^ 0} ■73 a o 3. _o s !3 o '5b U -2 s o cu 3 'E _c H 9J 01 o3 a bO « ■ft SCIRRHOUS CARCIXOMA 111 (liiiipling of tlie overlying skin resembling an orange or pig skin. Tims qnite early the overlying skin beeomes fixed to the growth, and the growth beeomes fixed to the pectoral fascia. The axillary lyinphatirs are not j)alpably enlarged early in the disease, bnt they are microscopically invaded long before they become palpable. The diagnosis shonld be made before this complication or ulceration of the skin tlevelops. llccraiion is a late stage of the disease, usually not appearing for one or two years after the development of the tumor. In some cases (atrophic scirrhus) ulceration may never occur. When it develops it is due to gradual in\'asion of the skin by the cancerous growth; a small ulcer first ai)pears, and this gradually increases in size. The scirrhous ulcer is quite typical: it is more or less circular in outline, fixed to the chest wall, red, dry, and quite dense; colloqui- ally it is known as the ^' rose ulcer" (Fig. 742). Occasionally as a Fig. 742. — Scirrhous carcinoma of breast showing typical "rose ulcer." Age sixty- eight years; duration three years; ulcerated six months. Has had no treatment, and growth is now adherent to ribs and inoperable. Two years and six months later, there was a large stinking ulcer, patient was extremely emaciated, hardly able to stand, and suffered dreadful pain. Episcopal Hospital. primary growth, but more often as a recurrence after operation, carcinoma grows either in many apparently isolated spots over the chest wall, or widely diffused in the skin; this is known as "squirrhe en cuirasse," as if the patient was covered with a "coat of mail" composed of carcinomatous nodules (Fig. 744). Prognosis and Treatment. — Owing to the slow growth and few subjective symptoms produced by the tumor, the patient often does not seek surgical advice until fixation and perhaps ulceration have occurred. The average duration of life in untreated cases of scirrhus is from two and a half to three years. The more atrophic the type, the longer will death be delayed; sometimes the patient drags out a painful existence for twenty years. If radical operation is done before fixation of the tumor, so that it is possible to remove all of the disease, freedom from recurrence for three years or more (which is classed as "ultimate cure") will result in from 50 to 70 718 SURaEKY OF THE BREAST per cent, of cases so treated. The reasons why operation should be urged, even with no better prospects, are stated at p. 725; and the I" ^1'^' — ^'^rcinoma simplex of left breast. Age forty-four j-ears; duration seven months from recurring trauma from work in mill. Note pig-skin dimpling, retraction of nipple, breast standmg out from thorax; emaciated face, and anxious expression. (See Fig. 744.) Episcopal Hospital. Fiu. 744. — Recurrent carcinoma of breast one year aftf r oxci^ion. Note cancer en cuirasse, fatter face and less anxious expression since being under hospital care; edema of left arm; involvement of right axilla. Two and a half years after operation, condition no worse, growth seemingly held in check by constant i-ray treatments. (Dr. Thos. S. Stewart.) Xo pain, less edema of arm. Episcopal Hospital. question of operabiHty is discussed in the same place. In inoperable cases palliative treatment, as outlined in Chapter IX, is indicated. I'AdKT'S DISKASh- OF Tlll<: MI'I'IJ': 719 Carcinoma Simplex or Acute Scirrhus is an iiitcrnu'dicite form between the scirrhous and incihiMary t\|)('s. The tumor causes increase in the si/e of the hreast, and ^rows rai)idl\'; the axilhiry lymphatics are i)alj)al)I\' in\ oh'cd (juite early in the disease, and all local symptoms (limitation of excursion of tlie hreast, retraction of the nipple, orange skin dimpliufi) occur sooner than in the scirrhous form fFig. 748). Ulceration also develops earlier and the ulcer is deeper hut is not fixed to the chest wall; its surface is covered with slouj^hs, there is more discharkin, to all portions of the mammary gland and its ramifications, and to the sur- rounding adipose tissue. The deep fascia overlying the pec- toral muscles and as far down as the epigastrium is widely infiltrated, and early invasion of the pectoralis major muscle may occur, as demonstrated by Heidenhain (1S89). Lymphatic extensions are di- rectly continuous with the main growth by fine columns of cancer cells. As the primary tumor in most cases is in the upper outer quadrant it is the axillary lym- phatics that are first invaded as a rule, and this invasion occurs long before the nodules are pal- pable. In most cases the nodes which first become palpable are those on the side of the thorax, about midway between the axillary folds. Let the patient's arm hang by her side, so as to relax the axillary fascia, and then palpate gently and attentively in this region. But in the case of a growth in the extreme upper and outer part of the gland, early extension may occur to the nodes highest in the axilla, and these rarely can be palpated. In time all the axillary lymphatics are involved, and even the supraclavicular nodes may become enlarged. In advanced cases lymphedema of the arm results ■ ■ ^^^ / € ^H BES^"* ■ 1 1 u Fig. 745. — L^niijhatics of the breast and axilla, involved in mamniarj- carcinoma. Episcopal Hospital. RADICAL OPERATION FOR MAMMARY CARCINOMA 721 from the axillary lyinpliatic" oljstruction; venous obstruction may also contribute to the edema; and pain from compression of the axillary nerves may be a very distressitiff symjitom. Lymphatic extension may also occur to the mediastiinmi, especially if the tumor grows in one of the inner quadrants of the breast; or extension may occur across the middle line of the body to the other breast, or even to the other axilla. Both breasts and both axillae always should be examined attentively. Finally reference must be made again to cancer en ciiira.s.sr, due to widespread carcinomatous lymphangeitis of the skin. Distant metastases by way of the blood-stream are denied by modern pathologists. Cancer cells in the blood excite thrombosis, and the thrombus as it organizes usually destroys or renders them harmless (Handley). Ilandley has also indicated that bone lesions (confined to the bones of the trunk, the proximal ends of the limbs, and the skull) are in direct continuity with the main growth; their site often is suggested by the presence of subcutaneous nodules over the affected bone, even before bone pains, or pathological fracture demonstrate their existence. In cases of scirrhus this sad event occasionally occurs before the local tumor is noted; and it is a rule always to consider the possibility of already present metastases before operating on a case of scirrhus, and always to inquire into the condition of the mammary gland in the case of obscure malignant growths in the bones or viscera. Radical Operation for Mammary Carcinoma. — Ablation of the Breast. — The general principles on which a radical operation for malignant disease is based were discussed- in Chapter IV (p. 132). The develop- ment of the technique of the modern operation for carcinoma of the breast is due largely to the teaching of C. H. ]\Ioore, Volkmann, Heidenhain, Stiles, Halsted, and Ilandley. Moore (1867) was one of the earliest to discard the theory of a cancerous diathesis, and to look upon it as a disease of purely local origin; in consequence he urged wide excision of the breast and all involved structures (pectoral fascia and muscle and enlarged lymphatics) in one mass. Volkmann (1875) always excised the pectoral fascia and emphasized the necessity of removing the surface of the pectoral muscles when diseased, and established the "three year limit," all patients free from recurrence after this interval being reckoned as "cures." Though recurrences (or perhaps new carcinomas) may grow after intervals of ten and even twenty or more years, it is found by the best operators today that recurrence after a free interval of three years occurs in only about 20 per cent, of patients. Heidenhain (1889) urged removal of the surface of the pectoral is major muscle in all cases, even when not visibly diseased, as on microscopic examination he found it always invaded by cancer cells. Stiles (1892) called renewed attention to the importance of wide local excision, showing the great area over which the mammary gland was spread out — sending processes to the clavicle above, to the axilla laterally, and well below the lower border 46 722 SURGERY OF THE BREAST of the pectoralis major, on to the serratus magnus, rectus, and external oblique muscles. Halsted (1894) introduced removal of the pectoralis major as a measure of routine, to facilitate clearing the axilla, in every case, whether the axilla was manifestly diseased or not; and he also insisted that the supraclavicular lymph nodes should be excised, and that the entire diseased tissue should be removed in one piece. Willy Meyer in the same year urged removal of the pectoralis minor in every case, and renewed the advice of Gerster (1885), who had advocated commencing the operation by the axillary dissection, which was left by others for the last step, and usually was under- taken only after the main tumor mass had been cut away. Finally-, Handley, in his Astley Cooper prize essay (1905), demonstrated anew the importance of the deep fascia as the main highway by which the carcinoma cells spread in all directions from the common centre of disease, and has shown the necessity of removing it in a wide circle on all sides of the growth, which should be taken as a centre, the circumference to which excision should extend having as radius the distance from the tumor to the clavicle. This excision extends laterally to the latissimus dorsi, medially well beyond the middle line, and inferiorly at least two inches below the ensiform process.^ The operation thus comprises removal of a very wide area of skin, the mammary gland with surrounding fat, the deep fascia, both pectoral muscles, and axillary lymi)hatics, in one viass. If this diseased mass is cut into at any point the contained cancer cells will be given a chance to escape into the surrounding healthy tis- sues, and recurrence will be very apt to follow. For the same reason all rough handling and tear- ing the tissues apart by blunt dissection should be avoided. Skin Incision. — So long as this removes a sufficient area of skin, its particular form is immaterial. A wound which cannot be closed completely is less likely to be the seat of recurrence than one which can, because there is less likeli- hood of diseased tissue remaining. I prefer Jabez N. Jackson's (Fig. 746) incision (190(3) for early cases with little apparent involvement of the skin. For the average case Rodman's incision is as good as any (Fig. 747). Only a portion of the incision is made at first, sufficient for the dissection of the axilla, which should constitute the first step in the operation. To postpone this to the last, as in Halsted's method, leaves the entire thoracic Fig. 746. — Jackson's incision for fani- noma of the breast, suitable for early cases. The rectangular flap is turned down- ward and the axillary flap upward in closing the wound. Episcopal Hospital. RADICAL (H'Kh'A'I'IOX FOh' M A M M A h'Y CARCINOMA '28 wound rx])ose(l (lurinjij the most tedious part of the oiH'ration; whereas, it' the axilhi is cleared first (and this may re((uire two liours or more in (hfhcult eases) the remainder of tiie operation may he eoinpleted in ahont fifteen minutes. Moreover, the hhxxl-supply is eontrolled nnieh more (>ii"eetively if each branch going to the tumor mass is secured at its origin. Tlie i)eetorahs major nuiscle is exposed first, its upi)er border identified, chimping or protecting the cejjhalic vein. A finger is tlien passed beneath tiie muscle, and it is di\ided close to its humeral attachment. The cla- \icular fibres of the jjectoralis major are next cut close to the bone. This exposes the pector- alis minor, which is similarly divided close to the coracoid process, and the axilla is fully exposed. If there are palpably enlarged lymph nodes at the apex of the axilla, the skin incision should })e extended upward across the clavicle, and the supracla\'icular nodes explored. If enlarged they should be re- moved. I'nfortunately it is not feasible to remove them in one mass with the axillary lymph- atics, and they must be excised separately. Then the axilla is cleared from above downward, working along the axillary vessels to the lower border of the latis- simus dorsi. Arterial and venous branches are clamped and cut close to the main trunks. Whenever the supply of hemostats is exhausted, all clamped points should be ligated, thus releasing the hemostats for future use. The main nerve trunks are carefully preserved, as is the median (long) subscapular nerve which supplies the latissimus dorsi; injury to this will affect the usefulness of the arm. Sensory nerves may be cut without compunction. When the vessels once have been dissected free the operation may proceed with greater rapidity. The entire axillary contents are turned toward the chest, and the lateral thoracic wall, from behind forward, is denuded of fascia; here the long thoracic ne^^'e (external respiratory) should be looked for and pre- served. The axillary wound is then filled with gauze. The skin incisions are gradually extended to outline the breast, and are extensively undermined, on all sides, leaving attached to them only enough superficial fat to prevent sloughing. The axillary contents and pectoral muscles are then turned toward the median Fig. 747. — Rodman's incision for carci- noma of the breast, suitable for most cases. The triangular flap below the clavicle is pulled downward, and the under- mined skin on the lateral surface of the thorax is pulled upward, the wound being sutured in the form of the letter T, the long limb lying in the long axis of the breast. Episcopal Hospital. 724 SURGERY OF THE BREAST line, and the dissection of the chest is continued from the lateral wall to the sternum. Here the perforating branches of the intercostals and internal mammary arteries will be encountered, and may cause troublesome bleeding if allowed to retract below the intercostal muscles before being clamped. The tumor mass now })eing free above, the dissection is continued downward, removing the deep fascia over the upper portir)n of the rectus muscle in the epigastric region. Fig. 748. — Ablation of the breast: the pectoralis major has been cut near its humeral insertion, and its clavicular fibres have been divided, exposing the pectoralis minor. The entire skin incision (indicated in the drawing) is not made at one time, but only as the operation proceeds. The tumor being thus removed, a puncture for drainage is made in the skin of the axilla, and a tube introduced. This is allowed to remain four or five days. The skin is then sutured, closing the wound as far as can be done without undue tension. The arm is dressed in a fully abducted position; this permits more accurate apposition of the skin to the axilla, prevents accumulation of wound discharges here, and facilitates return of the function of the upper extremity. When the skin is accurately adjusted to support the axillary struc- tures, it is very seldom that disability follows from cicatricial con- traction. Lymphedema may develop after the operation, especially when a thorough removal of the axillary lymphatics has been accom- plished. It may be treated by Plandley's operation (p. 270). Excel- lent motion is retained by the arm in spite of removal of both pectoral muscles, and the patient is little if at all inconvenienced by their loss. Murphy retains them as pads to fill up the hollow of the axilla, and removes the breast before beginning his axillary dissection. Few or no surgeons any longer approve of this method of operating. Tansini slides a musculo-cutaneous flap from the back across to the thoracic wound, permitting of its complete closure in every case. The immediate mortal if y of the extensive operation described above is very low — not more than 1 per cent, in skilled hands. Deaths are caused almost solely by visceral complications, such as pneumonia, cardiac disease, or uremia. RADICAL OPERATION FOR MAMMARY CARCINOMA 725 Affrr-irfatmrnt.-W'hvn the iiu-ision cannot bo sntiircfl completely, some surgeons prcl'(T to do skiii-^'riiftiii},^ at the <-oii(lusioii ot" the operation; while others postpone this niitil ^frainilation has commenced. Personally I believe it is better to do ni'ither, bnt to expose the frramj- lating surface to the .r-ray at suitable intervals. If this treatment is conducted by a skilled nintucnolo^ist, there seems nuich less tendency to recurrence, and where inoperable recurrence takes ])lace this treat- ment greatly relieves the pain, diminishes the discharge and fetor, and keeps the })atients comfortable (Figs. 740 and 744). Examination of the wound for recurrence should be insisted ujjon, at first monthly; then every three or four months, until the three year i)erio(l has elapsed. After this time the patient should rej)ort to her surgeon at least once a year, or immediately if any sj'mptoms arise. End RrsuJts of tlir RadicaJ Operation for ('(ircinonia of the Breast. — If the oi)eration is done in favorable cases (before there is ])alpal)le axillary involvement and before the tumor is fixed or the overlying skin ulcerated), about 70 per cent, of patients will be "cured" in Volkmann's sense; that is, they will remain free of recurrence for a period of three years. And of these clinical "cures," only about one- fifth will have a recurrence at a later date. If axillary invasion has occurred before the operation is done, about 25 per cent, of patients will be in good health after three years. These figures are conserva- tive, as better results are reported by those who do most of these operations. But the advantages of the operation are great even if recurrence or metastasis -eventually occurs. At the very worst, the patient will enjoy a number of months, perhaps several years, of good health, and will have hope of ultimate cure. Even if recurrence takes place a cure may still be possible by aid of a second or third operation. Finally, if metastasis occurs, and death results from this cause, it will be a very much less painful death than that from local recurrence, and the operation at least will have prolonged life and afforded an interval of comfort and of hope. Inoperable Cases. — Usually no operation should be undertaken in cases in which it is manifestly impossible to remove all of the disease. In most patients wdth the supraclavicular nodes palpably enlarged, no operation, however radical, wdll effect a cure; but if the tumor is not otherwise inoperable, the radical operation may be done, these nodes being removed at a second operation ten days or two weeks later. Only if they are very slightly involved is it safe to prolong the original operation for their immediate removal. Recurrences are to be treated on the same principles as the primary growth. Even fixation to the chest wall does not necessarily contra- indicate excision; the portions of ribs invaded may be removed. Palliative operations sometimes are done in inoperable cases. Very occasionally mere " ampidation" of the breast (p. 710), to remove a sloughing ulcer, followed by x-ray treatment, will promote the ■2() SURGEJiY OF THE CHEST WALL patient's comfort and prolong life even when cure is out of the question (Fig. 740). Cauterization with the actual cautery, or with chemicals, such as chloride of zinc solution (5 per cent.), sometimes will relieve discomfort by sterilizing the surface of a sloughing growth. Double oophorectomy, introduced by Beatson of Glasgow, in 1890, has been employed in a number of advanced cases, and in some patients shrink- age of the breast tumor and considerable relief has followed. Ampu- tation at the shoulder-joint was employed by Esmarch (1883) as a primary operation in one far advanced case, and has been practised a number of times since in cases of recurrence; and even interscapulo- thoracic amputation has been employed in cases of recurrence (Dent, in 1897, and later by others). Others have employed rhizotomy (p. 530), with marked relief of pain. SURGERY OF THE CHEST WALL. Congenital and Acquired Malformations. — These are of interest from a diagnostic point of view, but little can be done in the way of treatment. Birth i)ijuries occasionally result in deformities which persist through adult life (Fig. 749), but seldom entail any disability. The diagnosis is made from the history. Rachitic deformities, reference Fig. 749. — Birth injury of thorax. Orthopaedic Hospital. Fig. 750. — Fuuiiel lireast iracliiticj. Orthopaedic Hospital. to which was made at p. 418, develop during infancy or early child- hood, and are recognized by coincident symptoms of rachitis. The most frequent deformities are the "rachitic rosary," Harrison's groove, and pigeon breast; these seldom persist past the age of puberty. Funnel breast, however, may last through life (Fig. 7oO). Injuries Til Some of these deforiuities iiuiy he improved by gymnastic exercises, t)r by tlie use of ortliopedic apparatus, if treatment is begun in early childhood; but the disability is so slight in adult life that no active intcrfiTcnce is required. Injuries. — The most frequent injury is fracture of the ribs. This was considered at p. .S23. Simple contusions require no special notice. Severe lacerated wounds, with compound fracture of the ribs, usually are attended by visceral injuries (for which see p. 73.'-{). They arc caused by crushing injuries, explosions, etc., and often are fatal. If the patient survives, con- valescence is prolonged, and severe deformity may ensue (Fig. 751). In some cases a phenomenon known as traumatic asphyxia, or stasis cyanosis, follow'S sudden vio- lent compression of the chest (or abdomen) of short duration. This state is characterized by marked cyanosis of the head, face, and neck, usually sharply delimited a Fig. 751. — Deformity of thorax following injury by explosion in coal mine. Episcopal Hospital. Fig. 752. — Traumatic asphyxia; oxygen in- halations. Death in twelve hours. Episcopal Hospital. short distance above the clavicle, apparently by the collar. The patient looks as if he had been strangled (Fig. 752): the eyes are bloodshot, and the eye-lids may become edematous; there may be hemorrhages from the naso-pharynx or ears; convulsions or uncon- sciousness may occur. In addition to shock, there is irregularity or entire failure of respiration. The cyanosis, w^hich is petechial in appearance, may be due to extravasation of blood (true traumatic asphyxia) or to dilatation of the capillaries with blood stasis (stasis cyanosis). It is difficult to differentiate the conditions, which, indeed, often coexist. The mechanism by wdiich this state is produced is believed to be sudden compression of the thorax with the glottis closed, causing violent reflux of blood from the right heart. There may be interstitial and subpleural hemorrhages in the lungs, with 728 SURGERY OF THE CHEST WALL interstitial emphysema; and in some cases cerebral congestion and hemorrhages have been found postmortem. Treatment. — Treatment comprises measures to o^'ercome shock, with artificial respiration, and inhalations of oxygen. The pulmotor, a mechanical device for artificial respiration employed in cases of poisoning by illuminating gas, may be used with advantage. Surgical Emphysema. — Surgical emphysema is a term used to describe the esca])t' of air into the subcutaneous tissues. As previously noted (p. 301) it may occur in the face in connection with fractures of the nose, etc. The most usual form, however, is that due to thoracic injury; and the air escapes across the pleura from the lungs which have been punctured by a broken rib or ruptured by the compressing force. If the emphysema appears first at the root of the neck, and not at the site of injury, it is probable that the rupture of the lung is entirely subpleural, and that the air has escaped into the loose cellular tissues surrounding the bronchi, and eventually reaches the neck by way of the mediastinum. This subcutaneous emphysema may occur without any clinical evidence of severe intra-thoracic injury, but as auscultation and percussion are much interfered with by its development, it is probable that the deeper lesions often are overlooked. Occasionally a wound of the pleura, without injury of the lung, may cause the development of emphysema, the outside air being sucked into the wound by the negative intra-thoracic pressure. The air may spread far over the body, up to the scalp, dowTi to the groin, and even out along the limbs; the eyes may be closed up, and the patient may become so bloated that recognition will be impossible. Subjective symptoms, except those due to visceral lesions, are insignificant. Palpation of the areas affected produces typical crackling; the skin feels as if floated up from the muscles or bones by an effervescing liquid; the air may be driven from one place to another by the fingers, and pitting on pressure is apparent. The larger the source of supply, the more rapid will be the develop- ment and spread of the emphysema. In some cases only a very limited area is affected, and attentive examination is required to detect it; in others the emphysematous area increases rapidly in size as the patient is watched. Treatment. — Mild cases require no treatment; but usually, whether or not there is fracture of the ribs, the injured side of the thorax should be strapped, as limitation of the respiratory excursions will diminish the spread of the air. Where the emphysema is very marked, it has been recommended that multiple pinictures be made with a fine pointed bistoury, or tenotome, whereupon air will escape with a hissing noise, and the swelling will partly subside. As a matter of fact, if any treatment is necessary, it is much better to aspirate the pneumothorax, since as long as this continues air will escape from it into the subcutaneous tissues. The chief danger is infection of the subcutaneous tissues, with widespread cellulitis. Apart from this and visceral lesions, the prognosis is good. AXILLARY ABSCESS r29 Axillary Abscess. Tins inn\- he .superficial or deep. Tlu; fcjrmcr, wliicli i> more frt'(iiu'iit and loss serious, arises in connection with the hair t'oUlck's or sehaceous >- Fig. 7.50. — Abscess in left supra.spinous scess; duration three weeks. Xo fossa; duration one week; cause unknown. cause discoverable. Episcopal Hos- Incision evacuated six to eight ounces of pus. pital. Healed in six days. Episcopal Hospital. Symptoms. — A subpectoral abscess forms a rounded, tender, painful swelling below the inner part of the clavicle; it tends to point at the lower border of the pectoralis major (Fig. 755 j, or rarely may burrow through an intercostal space into the pleura. It is differentiated from axillary abscess by its position nearer the median line of the body, and by the relaxed condition of the axillary fascia and freedom of the axilla; and from arthritis of the shoulder by the slight impairment of the movements of the joint, which are quite free within a limited range. I have seen the condition mistaken for tuberculosis of the shoulder-joint. CMilES OF rilE h'lliS 7'M Treatment. — Tlie abscess should he opened hy an iiicisi(jii aloiij^ the lower l)order of the jjectorahs major, and shoiihl he drained with a tiihc. Musser collected 2)^ cases with 1)-) deaths. Subscapular Abscess. This is (piite rare. The pus hjrnis in the space hetwen the serratus magnus and the posterior thoracic wall. It cannot jioint anteriorly because of the attachment of the serratus ma^nnis to the lateral asjjcct of the thorax; it cannot escape internally because of the spinal connections of the scapula. The i)us, therefore, spreads either upward, and points beneath the trapezius, which is unusual; or downward to the angle of the scapula. If the existence of this condition is remembered, the diagnosis rarely will be difficult. The abscess should be opened at the lower angle of the scapula, and drained. In some cases the body of the bone may be trephined. Suprascapular Abscess. — Suppuration in the supraspinous fossa is another unusual condition (Fig. ToO). Unless the condition is borne in mind, the swelling may be mistaken for a sarcoma. The onset usually is subacute, and maj' follow the formation of a hematoma in the supraspinatus muscle as the result of trauma; or the lesion may be tuberculous and arise in the bone. The abscess should be opened and drained, unless it is thought to be tuberculous, when it should be treated as a tuberculous ab- scess elsewhere in the bo(h' (p. 483). Caries of the Ribs. — This usually is tul)erculous in nature. It may be due to extension from a focus in the vertebrae, or from a tuberculous pleurisy; or the disease may be primary in the ribs. In the latter case devel- opment of the afTection often follows injury. Usually the patients are adults, and there often is pulmonary tuberculosis or a tuberculous lesion in the bones, joints, or lymph nodes. Early formation of a cold ab- scess occurs, and this presents itself as a fusiform swelling along the course of one or more of the ribs. The ribs from the third to the eighth are oftenest affected, near the chondral or the vertebral joints. The disastrous results of spontaneous fistu- lization and secondary infection are as prominent here as elsewhere in the body where tuberculous disease is concerned. Interminable suppuration ensues, with numerous fistulse, and constant pocketing Fig. 757. — Extensive scars of both hyper- chondriac regions from previous operations for necrosis of ribs. Episcopal Hospital. 732 SURGERY OF THE ANTERIOR MEDIASTINUM of "hot" pus, which requires evacuation (Fig. 757). If seen before rupture occurs, the abscess should receive tlie treatment advised for cold abscess in general (p. 483). Tuberculosis may also affect the joints of the sternum; at the junction of the manubrium and gladiolus its development has been mistaken for fracture (N. B. Carson). Acute septic osteomyelitis of the ribs may occur, but is rare; also rare is typhoid periosteitis of the ribs, which may not develop for months or years after the attack of typhoid fever. Osteomyelitis may result in necrosis of the ribs, and resection of the portions affected may be required; in cases of typhoid origin, however, curettement of the carious surfaces usuallv is sufficient. SURGERY OF THE ANTERIOR MEDIASTINUM. Affections of the anterior mediastinum offer up to the present a very limited field for surgical care. Acute Mediastinitis. — Acute mediastinitis is the term used for a cellulitis of the mediastinum. It may follow a stab or gunshot wound, or may result from extension downward of a cervical cellulitis. There are pain, tenderness on pressure over the sternum, and con- stitutional symptoms of sepsis. Signs of cardiac, pulmonary, or tracheal compression may arise. Usually in the course of time pus is formed, and this seeks an exit for itself through an intercostal space close to the sternum, or possibly by rupture into a bronchial tube or the pleura. Lymphadenitis of the mediastinum usually is tuberculous. The onset of symptoms is less acute than in mediastinitis. Treatment. — When medical measures, w'ith cold locally, fail to relieve the symptoms, and especially when symptoms of respiratory obstruction arise, surgical intervention is called for, even before pointing of an abscess occurs. The operation consists in trephining the sternum, enlarging the opening with rongeur forceps, and evacuat- ing the pus by Hilton's method (p. 51). An abscess may be opened where it points, but even then it is usually necessary to cut away part of the sternum to secure free drainage. Mediastinal Tumors. — These give evidence of their presence by compression symptoms, and by an abnormal area of dulness on percussion. Tuberculous lymphadenitis is the most frequent non- neoplastic growth. The lymphadenoid enlargements of Hodgkin's disease and sarcoma are not so frequent as secondary desposits of carcinoma. Benign tumors, especially dermoids, also occur. As a rule no surgical treatment offers any prospect of cure; but palliation may be offered by splitting the sternum longitudinally to lessen the symptoms of compression. Should a benign tumor be found, it might be removed successfully. Friedrich recommends transverse section of the sternum above the third rib. Enlargement of the thymus gland is referred to at p. 693. PENETRATING WOUNDS OF THE THORAX 733 SURGERY OF THE LUNGS AND PLEURA. Subcutaneous Injuries. Siilxutaiu'ous injuries of the thoracic viscera usually arc accompanied by fractures of the ribs or sternum; but sometimes tlie hm in mind. It is recognized, moreover, that wounds which probably injure the heart should be explored (p. 286); according to Lawrow's figures only one out of ten stab wounds of the thorax implicates the heart. But when these two classes of stab wounds are excluded, there certainly remains a large number of cases in which it is at least extremely proba})le that only the lung has been injured, or that even though the pleura has been penetrated there is no visceral injury whatever; and it is interest- ing to compare the results secured in the case of uncomplicated pulmonary wounds in Zeidler's service, where every patient who con- sented was subjected to early operation, with those reported (1910) by IMoller from Korte's clinique, where no operations were done in such cases. According to Zeidler's immediate exploration plan the mor- tality in 52 uncomplicated cases was 27 per cent.; whereas Korte treated 19 such cases without one death. And the significance of this comparison I believe is not altered by the fact that in 78 per cent, of the cases explored by Zeidler and his assistants some visceral injury or bleeding from an intercostal vessel was found. From a consideration of these facts I think it is evident that no hard and fast rules can be laid dow^n for treatment, but that each individual case must be treated on its own merits. In fully equipped hospitals, I believe exploratory operation for stab wounds of the thorax will be indicated more often in the future than in the past; certainly more often than in the case of gunshot wounds or crushes. But I cannot believe that exploration in every case is necessary or desirable. If there is a possibility of injury of the heart, or of the diaphragm or abdominal viscera, exploration is imperative; but if this possibility seems remote, it is better to treat the patient expectantly. As indications for operation, then, may be recognized the following factors : 1 . Possibility of injury to the heart, to the diaphragm, or abdominal viscera. 2. Active hemorrhage from the wound. 3. Signs of internal hemorrhage, recognized by constitutional symptoms, and by steady increase in the amount of the hemothorax. It makes no difference whether this comes from the wounded lung or from a parietal vessel. The bleeding must be stopped. 4. Pneumothorax which develops suddenly some days after the injury. As pointed out by Moller this indicates sloughing or reopening of the wound in the lung; and immediate drainage of the pleura is 736 SURGERY OF THE LUNGS AND PLEURA required to prevent sepsis. Primary pneumothorax scarcely ever will be so severe as to demand relief; but if necessary the air may be aspirated through a fine needle. If this fails, the only relief lies in thoracotomy, by which the pressure within the pleura may be reduced to that of one atmosphere. Operation. — Usually a general anesthetic is required. Ether is the best, and if possible it should be administered by intratracheal insufflation (p. 154). The wound is carefully explored, cutting down layer by layer, until it is ascertained that the pleura has been entered. Then the incision is extended to a length of sLx or eight inches in the wounded interspace. By strong retraction of the ribs (for which the rib-spreader of ^Mikulicz is convenient) it may be possible to complete the operation without resecting any of the ribs. Resection of one or both ribs bordering on the primary incision may be done later if necessary. A bleeding intercostal vessel, which may be the only source of hemorrhage, should be looked for and ligated. The pleura having been widely opened, the thoracic cavity is tamponed (by fine silk tampons or those of handkerchief gauze if these are available), and the diaphragm is inspected, unless there is good reason to believe that it has not been injured. If a wound is found, it should be treated as described at p. 750. If bleeding continues, the lung is caught in volsellum forceps, and is drawn into the thoracic incision. This fixes the mediastinum, promotes cardiac action, and ventilates the other lung. The lung is then searched for wounds, and these are sutured with mattress sutures of fine chromic gut, introduced close to the border of the wound, passed deeply, but not drawn very tight. Round-pointed needles should be used. A wound of exit as well as one of entrance should be looked for. If the wounds cannot be sutured, they should be packed; or a very extensive wound may be "exteriorized" by suturing its margins to the edges of the parietal wound. After the pulmonary wound has been sutured the lung will expand if intratracheal insufilation is being employed, and the blood which has collected in the pleural cavity will be forced out of the thoracic incision. If it is not, the pleura should be wiped dry. No irrigation should be employed. The parietal wound is then closed in layers (pleura, intercostal muscles, and skin), icithoid drainage. If the anesthetic has been administered in the usual way it will be safer to leave a drainage tube in the incision for a few days; this should be just long enough to enter the pleura. In 22 cases where the wound was closed without drainage, subsequent drainage for empyema or abscess was required in only 13 (Stuckey); the other 9 patients recovered without any complication, and if all had been drained, all would have had empyema. Hernia of the Lung is rare. When congenital it may be due to defect in the chest wall, or may develop at the root of the neck. Acquired cases usually follow some months or years after injury of the thorax, the lung bulging out beneath the cicatrix. The swelling is sponge-like in consistency, crepitates on pressure, and is reducible; HEMOTHORAX 737 it increases in size (iuriiij^ forced expiration, may disappear spon- taneously during inspiration, and gives an impulse on coughing. Treatment.- Treatment seldom is required. If support by pads or adlit'sixc plaster does not secure relief, an operation may he under- taken, dissecting out the cicatrix, and repairing the wound hy over- lapping its edges in several layers. The pleural cavity need not be opened. Pneumothorax. — The presence of air in the pleural cavity as a complication of injuries of the thorax has been alluded to. Occa- sionally the condition arises from disease of the lung, usually tul)er- culous; but such cases have little surgical importance. The pneumo- thorax may be open or closed: that is, there may or may not be a wound of the thoracic parietes producing a communication between the pleura and the outer atmosi)here. If there is no external wound (when the pneumothorax is due to escape of air from the wounded or diseased lung), or if the thoracic wound is small or valvular, the pressure of the air in the pleura may be increased at each respiration, and a "tension pneumothorax" is said to exist. Symptoms. — The symptoms depend upon the rapidity with which the pneumothorax develops, and on the air pressure. A very suddenly produced pneumothorax may cause immediate death from distortion of the mediastinum, and interference with the action of the heart or the other lung. One of very slow onset may produce no appreciable symptoms. When traumatic in origin, the symptoms often are obscured by those of shock, internal hemorrhage, etc. Unless the lung is bound down by adhesions, the air fills the entire pleural cavity, and the entire side of the chest affected becomes tympanitic on percussion. There is absence of respiratory movements, no breath sounds are heard, and vocal fremitus is absent. If the air is under extremely high pressure a dull note may be obtained on percussion; this is rare. Almost always there is dyspnea; there may be cyanosis; the cardiac action may be embarrassed, and the pulse usually is weak, not very rapid, and may be irregular. Treatment. — In most cases of closed imeumotJiorax the air will be absorbed spontaneously within a few days, and no treatment is required. If dyspnea is severe the air may be aspirated. For this a very fine needle should be used, so as not to produce subcutaneous emphysema. In cases of o])en pneumothorax relief of symptoms usually follows closure of the external wound by suture or occlusive dressing. This restores the piston action of the diaphragm, ventilates the other lung, and facilitates heart action. If for any reason the wound cannot be closed, and the symptoms of a tension pneumothorax supervene, it is better to enlarge the parietal wound or to introduce a drainage tube, thus reducing the intraplem-al pressure to that of one atmosphere. Hemothorax. — Blood in the pleural cavity almost invariably is the result of injury to the thorax, either subcutaneous or penetrat- ing. The hemorrhage may be derived from the lung or from the 47 738 SURGERY OF THE LUNGS AND PLEURA internal mammary or one of the intercostal vessels. Bleeding from parietal vessels is not likely to stop of its own accord, owing to the negati\'e pressure within the pleural ca^aty. If the bleeding comes from the lung it will not cease until the intrapleural pressure equals the blood-pressure within the lung; but as this is only one-third as great as that in the systemic circulation, intrapleural hemorrhage from a lung wound will stop of itself much sooner than will bleeding from an intercostal artery. The physical signs are those of pleural effusion. The symptoms of internal hemorrhage iuflicate the nature of the effusion, and this may be proved by as])iration. The blood does not clot very readily, and forms an excellent cidture medium for bacteria. Hence there is great danger of secondary empyema. If infection does not occur, and the blood finally clots and becomes organized, extensive and perhaps disabling pleural adhesions may develop. I have operated on a patient with calcification of the entire pleura, the result of injury many years previously. Treatment. — This depends upon the rapidity of the hemorrhage as well as upon its extent. Rapid bleeding (indicated by the symptoms of internal hemorrhage and by rapid increase in the amoinit of fluid in the pleura) usually indicates an extensive pulmonary lesion, and demands operation, as described under stab wounds of the lung (p. 736). If the bleeding is slower, it is better not to interfere unless the upper level of the dulness (in the sitting posture) ascends as high as the spine of the scapula, or unless the symptoms of hemorrhage are very pronounced. Pneumc-hemothorax. — Pneumo-hemothorax is more frequent than either pneumothorax or hemothorax separately. The air rises to the upper part of the pleural cavity, and the blood gradually accumulates below. The physical signs are those of pyo-])neum()thorax, which are described in every text-book of general medicine. The diagnosis depends on a recognition of these, and on a history of recent injury and on the symptoms of internal hemorrhage. Aspiration of the fluid pro\'es its hemorrhagic nature. Differentiation from diaphrag- matic hernia (p. 751) may be difficult. Treatment has been discussed sufficiently under the separate headings pneumothorax and hemo- thorax. Chylothorax. — Chylothorax usually is due to rupture of the thoracic duct, which may occur as a complication in some cases of fracture of the spine. The effusion is left-sided, but owing to more serious injuries often is overlooked. Rapid emaciation is characteristic, but the diagnosis cannot be certain until some of the fluid has been withdrawn by aspiration; and microscopical and perhaps chemical stiuiy may be necessary then to determine its nature, as an effusion similar in macroscopical appearances sometimes occurs in cases of malignant disease of the pleura. Treatment is unsatisfactory. In some cases repeated aspiration has been followed by recovery. I'YO'rilOh'AX, OU KMI'YKMA TIJOh'AClS ToO Hydrothorax. llydiolliorax is tlio lonu used to »k'scril)(' a collec- tion of noii-iiiHammatory fluid (transudate) in the pleural cavity. It presents little suru'ical interest. Pleurisy or Pleuritis is an inHunHiuition of the pleura, almost iu\arial)ly of bacterial origin, and in the vast majority of cases due to infection transmitted from the lung. It may result from hematogen- ous infection, but this is rare. It is always present in some degree in cases of ])enetrating wounds of the thorax. In the early .stages of the inflanunation a plastic exudate is formed, and if the ])rocess stops here, recovery with more or less extensive pleural adhesions may occur. Such cases form about one-fifth of the total cases of pleurisy (Fraley, 11)07) and seldom come under surgical care. In about three- fifths of ( ases serous eft'usion occurs, and in about one-fifth more this eti'usion finally becomes i)urulent (pyo-thorax). If adhesions have formed early, or in a previous attack of pleurisy, the effusion may be encapsulated; its site then may be between the lung and the parietal pleura, between two lobes of the lung, or between the lung and dia- ])hragm. In cases where there are no adhesions the fluid lies free in the pleural cavity and forces the lung upward and backward into the spinal gutter. The symptoms of pleurisy with effusion are detailed in every text-book on general medicine, and need not be recounted here. The diagnosis is confirmed by exploratory puncture with an aspirating syringe. Treatment. — If the eiTusion is large and if no tendency to reabsorp- tion is manifested, and particularly if the constitutional .symptoms indicate suppuration, the fluid should be aspirated, as described at p. 147. The needle is passed close to the upper border of the rib, in the sixth, seventh, or eighth interspace, usually in the posterior axillary line or below the angle of the scapula. The site may be anesthetized by a hypodermic injection of cocain or by ethyl chloride spray. Seldom is it necessary to withdraw all the fluid, as the relief of tension secured by aspiration of a portion may hasten absorption of the remainder. Pyothorax, or Empyema Thoracis, is a collection of pus within the pleural cavity. It is the suppurative stage of pleurisy with effusion; but in many cases suppuration occurs so rapidly that no anterior stage of serous effusion can be recognized. In no case is there any sharp line of distinction to be drawn between the two conditions, as the serous exudate (when one exists) gradually becomes sero-purulent, and this in turn assumes the usual character of pus. The pus may sink to the bottom of the pleural cavity as a heavy flocculent sediment, and the supernatant liquid may remain com- paratively clear. Pyothorax is most frequent in children, especially as a complication or result of croupous pneumonia, the infecting organism being the pneumococcus. Pneumonia if followed by empyema in from 5 to 10 per cent, of cases. In adults men are affected much oftener than women, and the empyema results less often from a frank pneumonia; '40 SURGERY OF THE LUNGS AXD PLEURA in many cases the staphylococcus or streptococcus is the infecting organism, and these may appear as secondary infections in cases originally caused by the pneumococcus, which is a short-lived organism. Unless the pus is evacuated early, the parietal and visceral pleurae become thickened, and a fixed cavity is produced, which will hinder expansion of the lung even when the contained fluid has been removed. Adhesions may also occur, within the pleura, and much oftener than in cases of serous effusion the empyema is encapsulaied either on the surface of the lung, between its lobes, or between the lung and dia- phragm. In rare cases the pus may evacuate itself through one of the bronchial tubes, or may per- forate the diaphragm and form a subphrenic abscess. In children it is not unusual for a neglected empyema to break through an in- tercostal space and to point sub- cutaneously. In adults this is rare (Fig. 758). This condition is described as an empyema neces- sitatis. If the empyema ruptures externally, which is very unusual, a pleural fistula is left, and this scarcely ever heals spontane- ously. Ssnnptoms and Diagnosis. — Usu- ally the empyema is secondary to some thoracic condition (pneu- monia, bronchitis, injury) for which the patient has been under treat- ment. In children, in whom the condition is most frequent, an empyema very frequently is mis- taken for an unresolved pneu- monia; but this condition is rare in children, and if an aspirating s\Tinge is used, as it should be, for exploration in such cases, the diagnosis will be quickly cleared up. The physical signs in children may be very misleading, as the breath sounds may be quite clearly heard; this, with the persisting dulness on percussion, causes the resemblance to unresolved pneumonia. There may be Skodaic resonance above the dull area. But tactile fremitus is decreased, and the mere fact of a lingering pneumonia in a child should make one suspect an empyema. Xor should failure to draw pus at the first puncture make the physician conclude that it is absent, if the constitutional signs of sepsis persist. The pus may be too thick to run through the needle employed, or the collection may be encapsulated, and may not have been reached by the needle. In advanced cases, however, the diagnosis is easy; the temperature Fig. 75&. — Empyema necessitatis, pointing beneath left pectoral muscles. Age thirtj--two years ; phthisis for two j'ears: pneumonia seven months ago. "Abscess in thorax" for five weeks. (Dr. Harte's case.) Pennsylvania Hospital. PYOTHORAX, OR EMPYEMA THORACIS 741 contimu's ok'Nutcd, and thoiifili remissions may occur daily or oftener, the normal is not rtniclied. The apex beat of the heart may be dis- placed l)y laro;e otVusions; the intorsi)aces of the affected side may bnl^e; (Hlated veins may cover tliis side of the thorax; and it may seem iarfjjer than the heahhy side, though its resj)irat()ry excursions are less than normal or absent (Fig. 759). In adults the diagnosis of pleural effusion does not present the same difficulties, but the presence of pus rarely can be asserted positively unless j)aracentesis is done. Treatment. — A child almost in articiilo moriis may be saved by prompt evacuation of the pus, but the evacuation should not be too rapid in any case where there is marked dysjjnea, cya- nosis, etc., as abrupt change in the intrapleural pressure may cause sudden death. In any case of massive effusion (one extending as high as the spine of the scapula) it is well to withdraw half or three-fourths of the fluid by aspiration before proceeding to drain the chest. Murphy's Method. — Mur- phy aspirates the pus and at once injects two or three ounces of a 2 per cent, solu- tion of Liquor Formaldehydi (U. S. P.) in glycerin. This solution should have been made up at least twenty-four hours previously, so as to allow it to become thoroughly mixed and sterile. A week later the fluid is aspirated again, and it is found less purulent and more serous; another injection of the formalin-glycerin solution is given, and at the third or fourth aspiration the fluid is found to be pure serum. This fluid is allowed to remain in the pleural cavity, and is very gradually absorbed, as the lung expands and the chest wall sinks in. A year or more may elapse before all the fluid is absorbed, but as it is sterile the patient is in no way inconvenienced by its presence. Few other surgeons have adopted Murphy's plan of treatment, most preferring still to open the pleural cavity and drain the abscess. Naturally the earlier Murphy's method is employed, the more success- ful it will be; if employed as soon as the first evidences of suppuration appear in a pleural effusion, one injection may suffice for a cure. But in cases of long standing, where the pleura is much thickened Fig. 759. — Pyothorax on the left, following pneumonia. Age seven years; duration two weeks. Note x on apex beat, displaced to right; dyspneic expression; bulging of left intercostal spaces, and well marked intercostal depressions on right. Children's Hospital. 742 SURGERY OF THE LUNGS AND PLEURA and the limir is hound down by adhesions, I think tlioracotoniy, as (U'scrihed below, is to be preferred. Thoracotomy or Plevrotomy. — This is the oi)eration of opening the thoracic cavity for the purpose of draining an enii)yeina; a ])()rti()n of a rib is excised to ensure free drainage (Konig, 1878). The rib selected depends on the location of the pus, if this is encapsulated ; if the pus is free in the pleural cavity the surgeon chooses the sixth rib in the anterior axillary line, the seventh in the mid-axillary line, or the eighth rib in the posterior axillary line. It is said that if a lower rib is chosen, the ascent of the diaphragm may interfere with drainage; and if too high a rib is selected it may be above the level of the pus, and the lung may be injured. T. T. Thomas (1913) advocates resection of the eleventh rib close to the angle to secure dependent drainage, and secure prompt closure of the sinus. In children some surgeons prefer an intercostal incision, without resec- tion of a rib, but I believe even in these cases convalescence is more rapid if a larger opening is made. The operation may be done under local anesthesia if necessary: after anesthetizing the skin and subcutaneous tissues as usual, the needle is inserted in the intercostal space at the dorsal extremity of the proposed incision, and is pushed in until it strikes the rib, its point is then manipulated until the lower border of the rib is found, whereupon it passes through the elastic resistance offered by the external intercostal muscle; it is then pushed still a little further in, and about 2 c.c. of a 1 per cent, solution of cocain are injected around the intercostal nerve. This procedure is repeated in the interspace next below^; and after a few minutes the intervening rib may be painlessh^ resected. In many cases, especially in children, a general anesthetic (ether) is to be preferred. Dyspnea should be relieved by aspirating most of the pus l)efore beginning the operation. The patient is not to be turned o\'er on the healthy side, as this may cause arrest of respiration or cardiac action. By bringing the body well over the side of the table the operation may be done without much difficulty, as the patient lies supine. Of late I have always followed Elsberg's suggestion to have the patient lie prone; respiration is perfectly easy in this position and the operative pneumothorax causes less pulmonary collapse than in the usual position. An incision of about tliree inches is made along the rib selected, and the knife is carried directly down to the bone. Bleeding-points are clamped. The periosteum is incised and is stripped from the outer surface of the rib throughout the length of the incision, by means of a periosteal elevator. On the upper surface of the rib strip the periosteum from behind forward, and on the inferior surface strip it from before backward. Then the periosteum is also stripped from the deep (pleural) surface of the rib, keeping the instrument close to the })one. By this means the intercostal ^'essels, which are separated from the rib by its periosteum, are pushed aside with the soft parts. When the rib has been thus denuded throughout its entire circumfer- I'YOTIIOUAX, Oh' EMPYEMA TIIOUACIS 'AW Fig. 760. — Excision of a rib for empyema. eiK-e for a distaiur of about two iiiclics, a boiu'-cuttiiiK forcrps or a special costotoinc i.s used to divide the rib at one end of the incision. The portion of rib to l)e excised is tlien 2). Ji'^d the i)iitient is ii Iieij)less cripple. ( lul)- hing of the fingers is frequent (Fig. 494), and other joint changes may add to his misery (pnhnonarN' osteoarthroi)athy (j). 47(5). Treatment. Treatment depends npoii the extent and duration of the sinus. A small and recent sinus, which does not discharge \-ery much pus, often may he made to heal hy hisnuith paste injections (Ochsner, 11)09), as us(>d for tuber- culous sinuses (j). 4S4). This method, with skiagraphy, is valu- able in determining the size of the cavity within the thorax. When there is much purulent discharge it is desirable to check this before instituting any formal oj)cration; and this is best accom- plished l)y irrigation which may be employed wnth safety in these chronic cases. Potassium perman- ganate solution is very satisfactory. The cavity should be cleansed at least once daily in this manner. Sometimes the sinus is kept from healing by the presence of a drainage tube which has been lost inside the wound. This may be detected by a skiagraph, and its removal constitutes the first step in treatment. If drainage is not free, tlie sinus should be enlarged, under an anesthetic, and the surgeon should break up with his finger the adhesions between the lung and parietal pleura; and if the cavity is large, he should resect another rib at its most dependent portion, and drain from the lower opening. Information derived from use of the a:-ray may be an aid in the prognosis: if the collapsed lung is permeable to air the a:-ray will show decreased density during forced expiration; and if the lung shows a tendency to expand during coughing, it is probable no further operation will be required (Destot and Violet, 1904). For cases in which the lung is permeable, but where no tendency to expansion is apparent, decortication or discission, as described below, should be done. If the lung neither shows a tendency to expand nor is permeable to air, the only way to efface the pleural cavity is to resect the bony thoracic cage overlying it, and thus to allow the soft parts to fall in against the lung (Estlander, Schede). Decortication of the Lung (Fowder, Delorme, 1893). — This consists in opening the old cavity of the empyema by an intercostal incision or the resection of a rib, obtaining sufficient exposure to enable the Fig. 762. — Scoliosis, nine months after operation for empyema; fistula still discharges eight ounces of pus daily. Episcopal Hospital. 74(i SURGERY OF THE LUNGS AXD PLEURA surgeon to explore the entire interior of the empyema cavity. The most important step is to free the lung thoroughly from its attach- ments to the parietal pleura. This is best done by making an incision through the latter close to the outer or posterior margin of the lung along the spinal gutter. The fingers are then inserted between the posterior thoracic wall and the lung, and the latter is gradually freed. Its natural elasticity and tendency to expansion aid in this manoeuvre. When the lung is thus freed posteriorly it may be possible to peel the remains of the abscess wall off its surface. The thoracic wound is then closed with drainage, and the case is treated as one of recent empyema. The results are very satisfactory, the lung expanding and the abscess cavity becoming obliterated. Discission of the Pleura (Ransohoff, 1903) is adopted in cases where decortication proves difficult or impossible. If the dense membrane overlying and compressing the lung is scored by the knife, down to the lung tissue proper, the incision will gape widely; and if a number of such incisions are made in parallel and criss-cross lines, each inci- sion will gape so widely that the lung will expand to a very surprising degree. Thoracoplasty, Estlander's Operation (1877). — This consists in the resection of several ribs (three to five), for a considerable extent, directly over the old empyema cavity, in order to allow the soft parts of the thoracic wall to fall in against the collapsed and non- expansile lung. The cavity is thus wholly or in part obliterated. In very large cavities the operation may not effect a cm-e, but the result is "the difference between having a large abscess discharging a great quantity of pus, and a small sinus which weeps a little thin fluid." (J. Ashhurst, Jr., 1894.) The operation may well be combined with free separation of the lung from its parietal adhesions, especially po.steriorly — a modified form of decortication. Schede's Operation (1890) consists in resection of nearly the entire bony wall of the side of the thorax affected. This is exposed by reflecting an immense flap extending from the second costal cartilage anteriorly, to the costal margin below, and to the spine of the scapula posteriorly. After removal of the ribs, this flap is applied against the exposed lung. This operation has a high mortality and is rarely done at the present day, when earlier and more thorough treatment of the acute empyema enables the patients to recover without such immense cavities. In no cases should it be attempted until decortication and Estlander's operation have failed. Tuberculosis of the Pleura, usuaUy secondary to that of the lung or bronchial lymph nodes, presents little surgical interest except in cases with effusion. Most painless, slowly developed, and appar- ently causeless cases of pleural effusion in adults are tuberculous. The condition is recognized by the physical signs of pleural eftusion, and the nature of the fluid may be suspected from the patient's history. Diagnostic puncture reveals straw-colored or slightly turbid fluid, rarely blood-tinged. Tubercle bacilli seldom can be rrnKHciLosis of Tiih: Lcxas 747 (liscovcrcd, l)Ut a liij^li lym|)li()c\t(.' coiiiit iniiy.siijj;jft'st the tuberculous nature of the Huid. and inoculation experiments usually will confirm the diagnosis. 'Die coiKJition is to he regarded as one of cold abscess. Sect)ndary infection, from the ))erforation of a tuberculous cavity in the lung into the pleura, is not very uncommon, forming a pyo- pneumothorax. Secondary infection may also occur through the blood or from the unruptured lung. Treatment. Local treatment is entirely secondary in importance to the general treatment of the tuberculous patient. Only if the effusion is massive, and causes dyspnea, should any of the fluid be withdrawn by aspiration. If much fluid is withdrawn (hufiage may be done to the diseased lung, or a recently closed communication with the lung may be reopened. After some of the fluid is withdrawn the remainder may be gradually absorbed. If on aspiration the fluid is found to be verging on suppuration (from secondary infection), an ounce or two of formalin-glycerin solution (2 per cent.), should be injected. Under no circumstances should the pleura be opened by incision, or drainage be established: such a course surely invites secondary infection, with an external pyo-pneumothorax, and death usually occurs in a few weeks. Secundary tuberculosis in an open emjtyciua ravifi/ may occur, but is not so quickly fatal as a primary tuberculous pleurisy secondarily infected. It should be treated as other cases of open pneumothorax following empyema, with special attention to the patient's general health. Tuberculosis of the Lungs. — Surgery of this condition may be said to be still in an experimental stage, and has been applied mostly to advanced stages of the disease otherwise incurable. In 1898 ]\Iurphy introduced to surgical notice in this country, a plan of treatment, previously advocated (1882) by Forlanini, con- sisting in injections of nitrogen gas into the pleural cavity, to cause collapse of the lung and thus to induce rest and promote healing of the pulmonary lesions. Nitrogen is said to be more slowly absorbed than any other gaseous substance. Pneumonotomy, to drain cavities in the lung, has been done on numerous occasions; the first formal operation is the historic one of Baglivi in 1643. It is conceivable that with the present improvements in the technique of pulmonary surgery such operation may find a legitimate field in the future for the rare cases in which an apical cavity is not draining well, and in which no other discoverable tuberculous lesions exist. Partial pneu- monecloniy was done by Tuffier in 1891 ; he removed the apex of one lung, containing an early focus of tuberculosis. The patient recovered and was in good health four years later. ^Medical and hygienic treat- ment will cure such patients, and no operation should be done. Est- landers Operation was suggested in 1891 by O. H. Allis as a means by which collapse of a pulmonary cavity might be secured, with improved chance of its healing; and this operation has been employed by Quincke and others. Friedrich (1909) has employed Schede's method for the purpose of causing collapse of a tuberculous lung, 748 SURGERY OF THE LUNGS AND PLEURA the other hmg being lieahhy, or exhil)iting no evidence of active disease. Freeman (1909) resected the upper ribs, and after the wound had liealed adjusted a hernial truss over the apex of the lung to cause obliteration of a tuberculous cavity. Freund's operation of chon- drectomy, as in cases of pulmonary emphysema, has also been employed in cases of pulmonary tuberculosis, to overcome the thoracic rigidity which prevents aeration of the lung. Freund in 1910 referred to 8 such operations in patients with pulmonary tuberculosis. Pulmonary Emphysema. — W. A. Freund, having recognized since 1858 that some of these cases are caused by fixation of the chest wall due to ossification of the chondral cartilages, proposed in 1906, the operation of chondreciomy for their treatment. The costal cartil- ages of the second, third, and fourth ribs on both sides of the thorax are excised with their perichondrium, so as to prevent their regenera- tion. The operation appears to have been employed in nearly fifty cases, with a fair measure of success. Abscess and Gangrene of the Lung, which are not very frequent, may be regarded as different stages of the same affection. Most cases occur in adults, and follow pneumonia; some cases follow a pulmonary infarct from a septic focus elsewhere in the body; and some follow the lodgement of foreign bodies. The patients usually are in a very poor physical condition, with degenerations of the viscera, before the pulmonary condition develops. Symptoms. — Usually these develop rather suddenly as a compli- cation of the preexisting disease. There is profound sepsis. Physical examination reveals a localized consolidation in the lung, which may give the signs of cavity after expectoration of its contained sputum. The sputum from an abscess is great in quantity, and consists of thick yellow pus, not malodorous at first. The older the abscess the more fetid does the pus become, owning to saprophytic infection. In cases of gangrene, which usually is a sequel to abscess formation, this fetid character of the pus is very pronounced. If there is elastic tissue in the sputum it is not probable that gangrene is present, since saprophytic bacteria soon destroy it. Pleurisy, with adhesions, frequently occurs and may prevent perforation of the abscess into the pleural cavity with development of a putrid empyema. The use of the .T-ray is of much value in localizing the abscess. If exploratory puncture is done, it should be followed at once by operation. Treatment. — Operation should not be delayed if gangrene is pres- ent. The patient gets no stronger by waiting even for one day. Without operation 80 per cent, of cases of gangrene of the lung die. In Korte's 28 operations for abscess or gangrene, the mor- tality was 28.5 per cent. (1909). In Lenhartz's 111 operations for gangrene the mortality varied from 27 to 38 per cent. (1908). If the abscess drains well through a bronchus, operation may be post- poned. Whenever possible the operation should be done under anes- thesia by intratracheal insufflation, though Korte administered the anesthetic in the usual wav. The ribs overh'ing the site of the abscess STAB WOUNDS OF THE DIAl'lUiAdM 749 (whifh should ho (IcttTinincd het'orchaiidj are resected suhperios- teally, for a distance of three or four inclies. If the lung is not adhcTont to tlie pleura it should he sutured to it hy interrupted mattress sutures of chroniic catpiut, applied in a circle around the supposed site t)f the abscess. Soiuetinies the site of the ahsccss can be detected by palpation, being denser than the surrounding lung tissue. If the patient is not in very serious condition the second stage of the operation is postponed for a couple of days. If the lung is already adherent to the i)arietal })lcura, or if the patient's condition is precarious, the surgeon proceeds at once to open the lung. This is done by Hilton's method, first thrusting a grooved director into the lung, and when pus is found dilating the tract with dressing forcei)s. Some surgeons use the actual cautery for opening the abscess. Any loose necrotic masses of lung tissue should be removed, but if even lightly adherent they should not be disturbed The abscess is drained by a tube. Bronchiectasis. — For this condition surgeons do an operation similar to that for abscess of the lung; but though the condition is not curable by medical means, the cure by surgery may be worse than the disease. The persistence of the bronchiectatic cavity may not materially shorten the patient's life, and the risk of operation is very great. In Korte's 17 patients the mortality of the operation was 73 per cent. Tumors of the Pleura and Lung may be primary, or secondary to growths elsewhere. Primary growths are rare and very difficult to diagnose. ]Most of them are malignant in nature. Endothelioma and sarcoma occur in both lung and pleura, carcinoma onlj' in the lung. Tumors of the pleura invade the lung, and those of the lung soon attack the pleura. Of the secondary growths carcinoma is more frequent than sarcoma. Symptoms. — The symptoms are not clearly defined. Some cases of primary carcinoma of the lung are mistaken for tuberculosis. There is dulness on percussion, and the breath sounds are absent or may be heard distantly. Exploratory puncture may reveal a bloody pleural effusion, or there may be a dry tap. Blood in a pleural effusion signi- fies either tuberculosis or malignant disease. There is no fever and no leukocytosis. The increase in the physical signs is rapid. Cachexia appears early and is pronounced. Treatment. — There is little to do. If the pleura fills with fluid, and this causes dyspnea, thoracentesis may be done. A few cases of excision of portions of the lung have been recorded, the patients surviving the operation (Lenhartz). SURGERY OF THE DIAPHRAGM. Stab Wounds of the Diaphragm. — In the majority of cases the stab wound is received in the thorax, by a downward thrust, and a complicating wound of the pleura exists. This is almost always the 750 SURGERY OF THE DIAPHRAGM case in stal) wounds inflicted by Slavs, but Italians frequently stab their antagonists by an upward thrust, the stiletto entering the abdomen first. The left side is more often injured than the right. There are no characteristic symptoms, and the diagnosis can be made with certainty only by exploratory operation, except in the rather unusual cases in which the omentum or one of the abdominal ^'isce^a protrudes through the thoracic wound. It is the frequency of injury to the abdominal contents which renders these wounds so serious. In 55 out of 121 consecutive stab wounds of the thorax, recorded by Lawrow (1911), the diaphragm and abdominal organs were in\'olved. The wound usually is in one of the lower intercostal spaces, espe- cially between the seventh and tenth; but stab wounds as high as the second interspace have caused injury to the diaphragm. The liver is the most frequently injured of the abdominal viscera, then the stomach or spleen (Magula, 1910). Treatment. — Treatment is by immediate exploratory operation in every case in which a lesion of the diaphragm is suspected. The mortality without operation is nearly 90 per cent., and those patients who have survived the immediate injury have perished eventually from strangulation of a diaphragmatic hernia or other lesion which a prompt operation could have prevented. Thoracotomy is the oper- ation of choice, because by laparotomy it is \'ery difficult if not impos- sible (1) to reduce the herniated organs, owing to the negative pressure within the thorax, (2) to repair the wound of the diaphragm, (.3) to suture wounds of the cardia or fundus of the stomach, or (4) to repair damage to the lung. The technique of the operation is much the same as that for diaphragmatic hernia (p. 752). If the stab wound is abdominal, and laparotomy is employed as the primary operation, secondary thoracotomy may be necessary before the herniated organs can be replaced or the diapliragm sutured; such an operation is described as thoraco-Japarotomy. By the term combined operation is understood one in which the thoracic and abdominal cavities are opened by the same incision: this is best made in the eighth inter- space, dividing the ninth costal cartilage and the diaphragm as far as necessary to secure free exposure. If the case is not complicated by injury to the viscera, the mortality with prompt operation is less than 20 per cent.; in complicated cases it is about 05 per cent. (Magula). Gunshot Wounds of the Diaphragm, except when complicated by injury to the viscera, are so rare as to have little surgical interest, unless strangulation of a hernia occurs subsequently through the opening in the diapliragm. In most cases injuries of the thoracic and abdominal organs exist, and the surgeon has to employ either thoraco-laparotomy or the combined operation. Rupture. — Rupture of the diaphragm, a subcutaneous injury, is very rare. As extensive lesions of the abdominal organs are frequent, Deaver and Ashhurst advise laparotomy as the primary operation, so that hemorrhage and intestinal leakage may be controlled. If DIAPHRAGMATIC HERNIA 751 it is (lilliciilt to reduce tlie organs wliieii lia\'e l)eeii iierniated into tlie thorax, tiioracotomy should be done also; this usually is required to t'aeilitat(> repair of the diaphragm. Diaphragmatic Hernia may be due either to congenital or to trau- matic defect in the diaphragm. Owing to the negative pressure within the thorax, it is always the abdominal organs whieh prolapse through the opening. The most frequently herniated viseera are the stomach, eolon, omentum, small intestine, liver, duodemnn. and kidney — in the order named. Though a congenital defect may be present at birth, the hernia may not appear until adult Mfe. and may ])roduee no noteworthy symptoms until strangulation oecurs. In owT 90 i)er cent, of cases the hernia is on the left side, because the liver acts as a protection on the right. ^Nlo.st of the cases occur in the fetus, or in infants stillborn or dying soon after birth. In adult life sudden death from carrliac failure is a frequent termination, and the possibility of a diapliragmatic hernia always should be re- membered in considering the causes of sudden death. Symptoms. — Subjecti^•e symptoms often are lacking, the malfor- mation being found unexpectedly at autopsy. In the newborn, cyanosis and dyspnea are prominent, the left thorax does not expand properly, there is dextrocardia, and death usually results in a few hours. The adult patient may have suffered from mild indigestion, with distress after meals; but no alarming symptoms may arise until sudden cardiac failure or perhaps death occurs from acute over- distention of the herniated stomach. Strangulation is a frequent termination, being due to any sudden strain which forces a larger portion of the abdominal contents through the diaphragmatic opening. The physical signs of diaphragmatic hernia are much more precise in theory than in practice. Diagnosis of the condition in life, except by the aid of the a;-ray, is exceptional. The lower chest on the affected side is tympanitic, the breath soimds are very feeble and distant, vocal fremitus is lost, expansion is decreased, and the heart is dislocated away from the affected side. The same signs exist in pneumothorax; but in diaphragmatic hernia the diaphragm does not descend on deep inspiration, and causes which may produce pneumothorax nearly always may be absolutely excluded. ^Moreover, distention of the stomach with liquid will change the physical signs in a case of diapliragmatic hernia; but in pneumothorax the thoracic tympany and other signs will not be affected. Aspiration is to be condemned as a method of diagnosis, owing to the great danger of septic pleuritis or peritonitis. A history of sudden onset following severe strain (sometimes childbirth) or crushing injury, or occurring some years after a stab or gunshot wound of the thorax, is higlily characteristic of diapliragmatic hernia. Finally the relation of the stomach to the diaphragm may be determined by the use of skiagraphy after filling the stomach with bismuth emulsion or introducing a stomach tube filled with mercury. From the rare or congenital con- dition known as eventration of the diaphragm, which is associated with 752 SURGERY OF THE DIAPHRAGM hyperplasia of the left lung, diapliragmatic hernia sometimes may be distinguished by the history of the case, and by recognizing through skiagraphy that the diaphargm in the former condition remains still above the abdominal organs no matter how far upward into the thoracic cavity these may protrude. Treatment. — Immediate operation is required for recent diaphrag- matic hernia of sudden development, because the danger of strangu- lation is very great. Unfortunately most such cases are first seen by the surgeon after strangulation has developed, and the patient is too ill to justify the prolonged examination and numerous tests recom- mended in seeking to reach a correct diagnosis. But if the surgeon can ascertain that the patient has had a severe injury (crush, or pene- trating wound of the lower thorax or upper abdomen) even many years previously, the diagnosis and indications for treatment may become very apparent. If the true condition is recognized thoracotomy (Permann and Postempski, lSS9j should be done. In many cases inci- sion in the eighth intercostal space, without resection of ribs, has given adequate exposure. After packing off the lung with fine silk or hand- kerchief gauze tampons, any rupture or perforation of the abdominal viscera should be repaired, and they should be replaced within the abdominal cavity. Then the opening in the diapliragm should be sutured; when this is not possible the omentum may be stitched to its margins, or as a last resort the opening may be tamponed. If the operation has been done under difTerential pressure or with intratracheal insufflation anesthesia, the pleura may be closed without drainage. In other cases a tube should be left in for a few daj's. If no diagnosis other than intestinal obstruction has been made, laparotomy will be the operation employed; but if reduction of the hernia from below proves impossible, no hesitation should be fe't in proceeding to thoracotomy. CHAl'TKJi XXI. IIKKXIA. A hernia is a protrusion of a viscus through an abnormal opening in the walls of the cavity within which it is naturally contained. This is a general definition, and may he ai)plied to a hernia of a muscle through a rupture in its sheath, to a hernia of the brain through an artificial opening in the skull, or to a hernia of an abdominal viscus through an abnormal opening in the abdominal \valls. By long usage, however, the term hernia, when standing by itself, is applied only to protrusions of the abdominal viscera. This protrusion usually occurs through an aperture of the abdominal wall which transmits bloodvessels or nerves, through a congenital defect, or through one acquired as the result of operation or disease. If this protrusion occurs through a normal opening it is not called a hernia, but a prolapse; as a prolapse of the rectum through the anus, or of the uterus through the vagina. The term hernia also implies that the protruding struc- tures are still Covered by skin: thus when omentum or other structure protrudes through an incised wound of the abdomen, it is not called a hernia but a prolapse. In the great majority of cases of abdominal hernia, the viscus which protrudes carries before it a pouch of the parietal peritoneum, which is called the sac of the hernia-; and since this sac may remain as a pro- trusion even when it contains none of the abdominal viscera, a hernia has been defined as "a protrusion of peritoneum liable to contain, containing at times, or permanently containing any viscus or part of a viscus from the abdominal cavity." (Da Costa.) But as the abdomi- nal organs sometimes protrude through a part of the abdominal wall which has no parietal peritoneum (e. g., a hernia of the bladder), or slide down behind the parietal peritoneum, instead of carrying it before them as a protrusion (e. g., sliding hernia of the colon), I think it is better to cling to the old definition. If the sac protrudes and is empty that patient has either a reduced or a potential hernia, accord- ing to whether or not the sac has before been the seat of a hernia. A sac may exist for many vears without a hernia developing in it (p. 754). Nomenclature. — A hernia receives its name (1) from the region in tvhich it appears, as epigastric, lumbar, umbilical, inguinal, etc.; (2) from its contents, as a hernia of intestine (enterocele), of omentum (epiplocele), of bladder (cystocele), of rectum (rectocele), etc.; (3) from its condition, as reducible, irreducible, inflamed, strangulated, etc.; and (4) from its mode of development, whether of sudden develop- 48 754 HERNIA ment or slowly acquired. Various other terms, used in describing hernia, will be explained as they are encountered. Causes. — The predisposing causes of a hernia ma\' be either general or local. General Predisposing Causes. — (1) Age. Most hernise appear in infan- tile or early adult life; the longer one lives the less apt he is to have a hernia. But the number of old people alive is so much less than that of young adults and children, that among the aged hernia is relatively more common. (2) Sex. ]\Ien and boys are much oftener afflicted with hernia than women. There are two main reasons for this: first because of the weakness of the inguinal region in the male sex from the descent through it of the testicle; and, second, from the more active life men lead, and the greater frequency with which they are sub- jected to great abdominal strains. (3) A distinct hereditary tendency toward hernia is recognized, probably from the persistence of anatomi- cal defects at points of greatest strain. Local Predisposing Causes. — (1) Weakness of the abdominal wall. After an abdominal operation, a hernia may develop in the scar (incisional hernia, p. 772) : or as a consequence of injury to the motor nerves of the inguinal region from an operation elsewhere, an inguinal hernia subsequently may develop (Figs. 774, 788, and 792). Some- times a hernia appears first after a debilitating illness or pregnancy. (2) Increased strain upon the yarietes by the abdominal contents. The gradual deposition of fat in the omentum and mesentery increases the intra-abdominal tension, causes stretching of the parietal peritoneum, opens up the hernial orifices, and thus predisposes to the development of a hernia. The same train of events may occur in cases of ascites, of intra-abdominal tumors, of pregnancy, etc. (8) A hernia may be the effect of repeated efforts, in coughing, in straining at stool, in urinat- ing (when there is some urinary obstruction) (Fig. 798). (4) The existence of a congenital sac predisposes the patient to the develop- ment of a hernia, though observations in the dissecting room show that many patients with preformed sacs pass through life without any evidence of a hernia. Structures Composing a Hernia. — In a typical case a hernia is composed of a pouch of parietal peritoneum, called the sac; of the contents of the sac; and of its coverings, which are the structures of the abdominal wall, muscles, fascia, and skin (Fig. 763). Sac. — The sac, as noted already, sometimes is wholly or in part deficient. Typically it is composed of a neck (that part which com- municates with the peritoneal cavity), and a body (that part which surrounds the protruding viscera). The apex of the sac is ']t<. fundus. The sac may })e congenital or acquired. I believe, with Russell and Murray, that the sac is congenital in a far larger proportion of cases than is commonly thought. This preformed sac renders the patient the potential possessor of a hernia; but until the hernia develops ("comes down" is the colloquial expression), the i)resence of the sac in most cases cannot be determined (p. 1058, congenital hydrocele). STRUCTURES COMl'OSISC A IIKRMA 755 Perito/ifum .Transversalts /irsaa Muscle . . . Skin i Sup. fascur. Fig. 763. — Diagram to show a hernial sac, its contents and coverings. The c()H(/rnilal .vac is fouud oftciu'st in inj^uinal liiTuia, Ijut occur.s frequently also in the femoral form, and sometimes in umbilical hernia. It nia\' he \ery lar<;e, hut usually is (juite small until distended hy the protrudinji,' ahdoniinal contents. The arqnirrd .sac usually is slowly developed from gradual stretching of the parietal peritoneum: at first the neck of the acquired .sac is its widest part, hut as the sac increases in size it becomes more or less pear-shajjcd, the neck being relatively narrow; then the sac continues to increase in size by the pressure of the contained .structures, but, as a rule, the neck does not enlarge at the same rate but remains relatively small. The wall of the sac, at first like the neighboring ])arietal peritoneum may become much thickened from inflammation, and its neck may undergo cicatricial contraction. The sac usually becomes densely adherent to the surrounding parts, especially at its fundus; and though the contents of the sac may be returned to the abdomen, as long as the empty sac remains recurrence of the hernia is to be expected. In hernia of long duration the neck of the sac may be shifterl, by the pull of its contents, downward and toward the median line of the body. The Contents of the Sac may be almost any of the abdominal viscera, but the most frequently herniated structures are the intes- tine fenterocele), and the omentum (epiplocele). In infancy and young childhood the omentum seldom is found in a hernia, owing to its undeveloped state; but in adults, particularly those who are obese, it is the most frequently found of all structures. The lower ileum is the portion of the bowel most often found in a hernia, because it has the longest mesentery and lies nearest the inguinal and femoral openings. Hernia of the large bowel is infre- quent, owing to its relatively short mesenteric attachments. The cecum may be drawn into a hernia by a coil of ileum already there; but the sigmoid is sufficiently mobile to find its own way into a hernia. A single coil or several coils of intestine may be found in the sac, or the hernia may be formed only by a portion of the wall of the intes- tine; this latter condition (Fig. 764) is described as Richters hernia (1778). A hernia of ^Meckel's diverticulum (Fig. 7()5) is known as Littres hernia (1700). When the herniai contents remain long in the sac, they usually become adherent to its walls and often are matted together. In this way a hernia may become irreducible. When both omentum and intestine are in the sac (entero-epiplocele), it usually is the omentum which enters it first. The omentum generally lies in 756 HERNIA front of, or even completely surrounds the bowel, and the bowel may be caught in apertures or depressions in the mass of omentum and thus may become strangulated. Unless the hernia is inflamed or strangulated there is little or no serum within the sac. Fig. 764. — Partial enterocele, or Richter's hernia. Drawing made from a caee of strangulated hernia in the Episcopal Hospital. The Coverings of the sac \\ ill be described in connection with each particular form of hernia. «|]»i Fig. 765. -Littre's hernia — a hernia of one of the intestinal diverticula (Meckel's diverticulum). Reducible Hernia. — This is one in which the contents can })e replaced within the abdominal cavity. It is the most frequent variety, since almost every hernia is reducible when it first appears, and becomes irreducible only after the lapse of years. For months or years before the hernia appears the patient may have felt a weakness in the region where the protrusion afterward develops. If the hernia develops gradually, there may be at first the merest bulging of the parts during straining efforts; later a small rounded tumor may be seen. This can be reduced easily by the pressure of a finger, and usually disappears spontaneously when the patient lies down. In cases of hernia prescjit at birth, or of sudden though later development, or of long duratit)n before seen by the surgeon, the protrusion often is of considerable REDUCUiLE IIF.RMA ITu size. In time tiie greater part ol" the alxloiiiiiial contents may descend into the sac. Tlie ontline of a liernia is more or less ronnded or oval, usually being less broad at the neck of the sac than elsewhere. The hernia increases in size when the patient stands up, coughs, or strains; it disap})ears either spontaneously or by gentle pressure when he lies down; and in most cases it reappears again if he once more stands up and coughs. When he coughs there usually is a distinct impulse transmitted to the hernia, and this often can be seen and almost always can be felt. Enterocele. — If the sac contains intestine only, the hernia is smooth, feels elastic, often gurgles on palpation, and usually is resonant on percussion. The impulse is well marked. Reduction usually is accompanied by a distinct gurgle and by a characteristic sensation well described as a "flop." Epiplocele. — An omental hernia feels denser, more fibrous or doughy to the touch than an intestinal hernia; it is irregular in outline; gives little or no impulse on coughing; and is dull on percussion. Reduction is not accompanied by any gurgle, nor by the "flop" so characteristic of bowel slipping back into the abdomen. In the enter o-epiplocele the symptoms of the two separate forms are combined. It seldom is possible to ascertain what portion of the gut forms the hernia. In umbilical hernia the transverse colon is most often found; and in inguinal and femoral hernia, the ileum. The cecum is much more frequent in right-sided inguinal hernia than elsewhere, but is not very unusual in a left inguinal hernia. In femoral hernia the omentum and small bowel are most often found. Treatment. — It is necessary for a hernia to be cured, whenever possible, because of the grave danger which may accrue to the patient from the occurrence of strangulation. A cure can be obtained only by an operation, by which the sac of the hernia is removed, its neck closed, and the structures of the abdominal wall repaired in such a manner as to prevent recurrence of a hernia. This is the best treat- ment in every case in which an operation is not contraindicated ; but the operation requires skill for its performance, and sometimes is very difficult. It should not be attempted by the occasional operator. Even if the best treatment (that which results in cure) is contra- indicated or is refused, it is still necessary that the hernia be treated. An untreated hernia tends constantly to grow larger and to become irreducible. It is possible to keep a hernia reduced by the use of apparatus (known as a truss) which exerts pressure over the neck of the empty sac, and prevents descent of the hernial contents.^ It used to be taught that in some cases the prolonged use of a truss might cause obliteration of the hernial orifice by exciting adhesions of the 1 I mention only to condemn the attempts of some charlatans to cause closure of the neck of the hernial sac by injecting paraffin in the surrounding tissues (Fig. 766). 75S HERNIA ( )]>!)( )si 11 (if layers of peritoneum. This oceasioiuilly occurs in infants, hut in the vast majority of cases, though a truss may keep the hernia reduced so long as the truss is in place, no obliteration in the neck of the sac is caused, and its contents tend to return at once when the truss is removed. If the neck of the sac becomes constricted from prolonged use of a truss (and this is not unusual), the hernia will be more apt to become strangulated, if it comes down, than if no truss had been worn. If no treat- ment at all is undertaken, the hernia constantly increases in size, is very apt to become irreducible, and the patient must endure the discomforts of this condition as well as run the added risk of stran- gulation w^hich an irreducible hernia entails. The contraindications to operation in the case of a reducible hernia are only those which contraindicate any operation, however trivial (p. 760). There are no local con- ditions which contraindicate operation in cases of reduci- ble hernia. Even immense size of the hernial orifice, with excessively weak ab- dominal walls, is a condition that may be overcome by proper methods (p. 774). K truss is an apparatus designed to support a hernia. It should keep a reducible hernia reduced. It is applied around the body, and has a pad which makes pressure over the hernial orifice. Most trusses are for inguinal or femoral hernia, and are applied around the pelvis between the iliac crests and the trochanters of the femora (Fig. 792). A truss may be made of steel covered with leather or hard rubber, causing elastic pressure over the hernial orifice; or it may be made entirely of leather, and depend on the tension with which it is buckled in place to retain the hernia. Trusses are also used for umbilical hernise; and the abdominal belts, used to support ventral and inci- sional hernia may be considered a form of truss. There are certain featu res which ever}- truss should possess: it should retain its position without extraneous aid; it should keep the hernia reduced in all positions of the body, and during coughing, sneezing, defecation, etc.; it should not cause irritation of the skin overlying the hernia or elsewhere; and it should be easily kept clean. The patient must have at least two trusses, in case one of them is Fi( AIa^~< )f piirafiin in inguinal canal and scrotum, injected on two occasions, several months ago, in effort to cure a hernia of twelve years' duration. Patient aged thirtj'- eight years. Hernia now in scrotum. Epis- copal Hospital. lliRKDVCllilJ': IIKUMA 7.V.) hrokoii. I'lic trusses suital)lt' tor the (liU'crciit tonus of licniia will he described under special licniia' (p, 7.SG). Do (larnio says a jiatient wlio wears a truss is a eiirouic invalid, and tlioufj;li this statement is somewhat of an exaggeration, it is al)solutely true tluit such a i)Htient nuist ()l)serve certain rules of con- duct if he wishes to continue in j^ood healtli. lie sliould he kept under his pliysician's ohserx ation. A truss requires as strict oversight as any other orthojjethc ai)i)liance (p. 517). The truss must always he applied while the i)atient is recumhent, after reduction of the hernia; it need not he worn at night, hut it should he reapplied every morning het'ore the patient gets out of hed. It must never he taken off except w'hen he is lying down. When he takes a hath he must wear the truss in the tuh. lie must not make any sudden exertion or strain at any time. He must lift no heavy weights. He must not go swimming. He should he debarred from all athletics except the lightest exercises. If he wants to be cured of his hernia, let him he operated on. Other- wise he must endure the limitations which truss-wearing requires. The possibility of strangulation of his hernia should he ever present in his mind. Should it occur it will force him almost always to an immediate operation to escape death; and he will be unable to choose either the time, or the place, or the surgeon for such an operation. Irreducible Hernia. — The commonest causes for irreducibility of a hernia are inflammatory adhesions affecting its contents. These may he between the sac and its contents, or adhesions of the coils of bowel to each other, to the omentum, etc. The most frequent cause is adhesion of the omentum to the sac. The bowel rarely becomes adherent to the sac. Intravisceral adhesions often prevent reduction even when no adhesions to the sac wall exist, because the contents are amal- gamated into a mass too large to pass through the neck of the sac. A hernia may be apparently irreducible, because manipulation cannot force hack in a short time, through a small orifice, a large mass of intestines or omentum which have taken years to descend. There is no strangulation present in an irreducible hernia, though a strangulated hernia may be irreducible. The diagnosis of an irre- ducible hernia depends upon recognizing that the protrusion is at one of the usual hernial orifices, on ascertaining tlie history of its develop- ment, and on the physical signs, which are the same as in a reducible hernia, with a few^ self evident exceptions. An irreducible hernia presents an impulse on coughing; it constantly tends to become larger, and the patient suffers from a sense of dragging, from digestive dis- turbances, and often from intermittent attacks of constipation and diarrhea. Though a patient may live for many years with an irre- ducible hernia, he is in constant peril because the prolapsed viscera are exposed to trauma, and are liable to repeated attacks of inflam- mation or obstruction; and strangulation is much more apt to occur than in the case of a hernia which is retained b^■ a truss. 7G0 HERNIA Treatment. — The cure of an irreducible hernia is more difficult and dangerous than that of a simple hernia, and can he secured only by operation. Except in the very old, or those with severe constitutional or organic disease, or those with most enormous herniie, operation always should be urged upon the patient. It is extremel}" desirable to reduce the size of these large hernia^ before any operation is under- taken, and even if no operation is done the patient may secure much relief from the preliminary treatment. This plan is to keep the patient in bed, on spare diet, with a course of mild purging, and frequent enemas, so as to secure complete evacuation of the })owels. Absti- nence and rest will reduce the amount of fat in the omentum and mesentery; and recumbency, combined with elevation of the foot of the bed, will bring the force of gravity to aid in securing reduction in the size of the hernia. This method appears first to have been advocated by Sir Astley Cooper in 1828. In most cases a partial reduc- tion at least can be secured by resort to taxis (p. 766) after a couple of weeks of this preparatory treatment, and sometimes the entire hernia can be reduced. In these cases of immense hernia, if the surgeon thoughtlessly undertakes an operation without such preparatory treatment, he may find it impossible to make the viscera enter the abdomen even after this has been opened. If the hernia can be reduced to ordinary size before operation is attempted, this should be as successful in obtaining a cure as in cases of reducible hernia. If the patient refuses operative treatment, the application of some form of support, in the nature of a "bag-truss" or suspensory may somewhat alleviate the symptoms. Inflamed and Obstructed Hernia. — These conditions are met with almost solely in cases of irreducible hernia. Inflammation may occur from accidental trauma, from unskilled or violent attempts at reduc- tion, from the pressure of an ill-fitting truss, or from changes in the contents of the sac. Among the latter attention may be called to the occasional presence of the vermiform appendix in the sac, with the possibility of appendicitis. Ohsirudion of a hernia is said to occur when the normal course of gas or feces through the herniated bowel is interrupted ; this may result from intestinal indigestion with accumu- lation of flatus, or from fecal impaction (p. 889). The symptoms of inflamed and obstructed hernia are much the same, consisting in local pain, tenderness, nausea, and perhaps vomiting; the hernia still gives an impulse on coughing; and flatus is passed by the anus, though there may be constipation. The symptoms are decidedly less severe than in the case of strangulation. Treatment. — The patient should be put to bed, and should lie in a position which relaxes the hernial orifice; an ice bag should be applied locally; an enema should be administered; nothing ichatever should be given by mouth; and if the symptoms are severe or if they do not subside in the course of a few hours, operation, as in cases of stran.- gulation, becomes imperative. In any case where the condition of strangulation cannot be positively excluded, immediate operation should be done. STRANGULATED HERNIA TCI Incarcerated Hernia. — This is one wliicli, th()ii<^li ordinarily re- (lii(il)le, lias tor some reason become temporarily irredncihle (l)e (iarmo). This eomplieation occurs most often in larj^e herniie, and usually is due to unskilful attempts at reduction, resulting? in some slight twist in the howel which renders the hernial orifice relatively too small to allow reduction. Wiiile there may l)e some local pain and tenderness, there are no symptoms of stranj^ulation present. Treatment. — Treatment consists in rest in bed, with the foot of the bed elevated and the ])atient so ])laced as to relax the hernial orifice. An ice bag or cold coil should be applied to the hernia, and the surgeon should not attempt to reduce the hernia until the acute symptoms have had a chance to subside; he maj^ find then that the hernia has been spontaneously reduced, or that its reduction })y taxis (p. 760) is easy. If the symptoms do not subside within a few hours, taxis should be tried, and if this fails, operation should be done as in cases of strangulated hernia. Strangulated Hernia. — This is one in which the circulation of blood is obstructed or entirely arrested. This serious occurrence is lial)le to bring on all the usual consequences of strangulation, which are studied at p. 762. The cause of strangulation of a hernia is not always evident. It is clear that a constriction exists, pressing upon the protruded struc- tures and interfering with their circulation. This constriction may be either in the sac wall, in the surrounding structures, or inside of the sac. Constriction by the sac itself is rare, especially' in children; the site of constriction usually is at the neck of the sac, particularly in the case of patients who have long worn a truss and in whom the sac and its neck have undergone cicatricial contraction. In some cases of congenital sacs points of constriction may exist elsewhere than at the neck (Fig. 780) ; and in some cases constriction may occur from bands of inflammatory adhesions formed within the sac. Extra-saccular constriction is by far the most frequent form and usually occurs at the abdominal opening in fascial or tendinous tissue through which the sac and its contained viscera pass. Intra-saccular constriction, which is rarest of all, may be due to torsion of the contents of the sac, or to the bowel being caught in an aperture or pocket in the omentum. Mechanism of Strangulation. — As the neck of the sac and the abdomi- nal opening through which the hernia passes are not muscular, but fibrous, and hence have no power of active contraction, it is evident that in cases of extra-saccular as in those of intra-saccular constriction the prime cause of strangulation lies in the contents of the sac. If the hernia previously was reducible, these changes in the contents of the sac usually b^gin as the state already described as incarcera- tion of the hernia; in the case of irreducible hernia the first changes usually are those described as inflammation or obstruction of the hernia, and they may be brought on by the unwelcome intrusion into the sac of a coil of gut or a plug of omentum never before present. In some patients a hernia which is suddenly developed becomes stran- 762 HERNIA filiated iinmodiately on its first appearance; sucli a strangulation is apt to cause rapid and very serious changes in the contents of the sac. A siniihir chain of events usually occurs when a hernia suddenly pro- trudes into a sac which has long been empty, especially if the use of a truss has caused cicatricial contraction in the neck of the sac. This form of strangulation may he described as ixnde to distinguish it from that of more chronic onset, which usually is i)receded by incarceration, inflammation, or obstruction of the hernia. All irreducible hernife are more liable to strangulation than those which are reducible and are retained by a truss. An irreducible umbilical hernia is especially liable to strangulation; and, of all forms, a femoral heniia is most prone to strangulation. Neutral and inci- sional hernise very rarely become strangulated. Structural Changes Occurring in Strangulation. — Probably in every case the first change is obstruction of the venous circulation of the contents of the sac; the arterial circulation is less rapidly affected because of the higher blood-pressure in the arteries and their more resistant walls. Arrest of the venous circulation causes the blood to be dammed back into the capillaries while these are still receiving blood from the arterial side. The result is stagnation of the blood, and edema of the extravascular tissues. Almost at once the hernia becomes too large to })e returned through the orifice by which it had escaped. If intestine is strangulated, intestinal obstruction (p. 884) is present as well as strangulation, and usually precedes it. Strangnlatiou of bowel causes the rapid outpouring of serum which may distend the sac; it will be greater in amount if the strangulation is very slow in onset than if the entire circulation is arrested immedi- ately. At first this fluid is pale yellow, clear, and sterile, and perhaps should be considered a transudate rather than an effusion; but very soon it becomes inflammatory in character, turning cloudy from the increase in the number of leukocytes present, and often is })loody, and in later stages of strangulation, brownish or black. Bacteria soon penetrate the walls of the obstructed bowel. If the strangulation is not promptly relie\'ed, the bowel, which at first is congested, bright red, soggy, and with its natural lustre but slightly impaired, becofnes purplish or even black in color, and may be covered with patches of inflammatory lymph. Actual gangrene quickly follows: the intestine loses its lustre entirely, and becomes soft, doughy, and grayish black; the peritoneal coat strips easily, the muscular coats are friable, and the bowel is very easily torn. In many cases definite rings of con- striction are found at the points of strangulation: usually the con- striction ring at the distal (anal) end of the strangulated loop is more pronounced than that at the proximal (gastric) end. The bowel below the constriction is nearly normal in appearance, or if anything rather paler than normal and collapsed ; that proximal to the constric- tion is distended, congested, and more nearly resembles the gut which has occupied the hernial sac. When the bowel becomes necrotic, or even before, merely as the result of intestinal obstruction, death from STRA NdVI.A TKl) II A'/.'A 7.t 7f)3 toxemia inav occur. If life is proloii^u'd. the slou^rii may separate from tlie intestine, resulting; in intestinal perforation mto tlie hernial sae, which then hecomes the seat of a fecal abscess. The overlymf^ tissues mav next become inflamed, and in rare instances this fecal abscess has opened spontaneously throiiKb the skin. In many cases septic inflannnation spreads to the peritoneal cavity, and f^'cneral periti)nitis is the cause of death. This may occur from perforation of the bowel at the point of constriction iVh^. 7()7), with escai)e of fecal contents into the peritoneal cavity, or from propajration of milam- ination along the coats of the bowel above the constriction. There may be a volvulus of the intestine leading up to the hernial ring, within the abdominal cavity. p,p 767 — Rnecimen of gangrenous small intestine resected in a case of strangulated femoral hernia Sesevfnty-one years; hernia strangulated for two weeks before fperatTonFo^al abscess in sac, bowel ruptured just above proximal constriction. Death twelve hours after operation (spinal anesthesia). Episcopal Hospital. If omentum is strangulated there is not much serum eflfused in the sac' The omental veins are found distended, dark blue or black, and perhaps thrombosed. The omental fat becomes pinkish red at first, feels denser than normal, and does not bleed readily if incised; later it becomes gravish white and perhaps necrotic. Symptoms of Strangulated Hernia.— In almost every case the patient has had a hernia for some time before it becomes strangulated. Lsually following a muscular strain (perhaps merely a mis-step, exuberant laughter, etc.) a sudden pain is felt at the site of the hernia. It the hernia was not down at the time of the accident, it slips out suddenly, even escaping from under a truss if one was worn. If the hernia was down alreadv at the time of the accident, whether irreducible or not, it feels to the patient as if it had increased in size from the protrusion 764 HERNIA of additional bowel or omentum. If the pain is very severe the patient may fall to the ground in a state of shock. The pain is followed very soon by a general abdominal pain which at first is colicky, becomes progressively worse, and which later is constant, not intermittent, // not checked by opiates this pain does not leave the patient until gan- grene has occurred or until the strangulation is relieved. Spontaneous cessation of pain therefore is a bad sign; it is accompanied by a false sense of security, and is soon followed by extreme prostration, and signs of impending death as in cases of intestinal strangulation from other causes. If the hernia is an enterocele, the usual symptoms of intestinal obstruction (p. 885) de\elop xevy soon after the occurrence of the strangulation. The initial colicky pain, in almost all cases but not always, is accompanied or followed by nausea and vomiting. The vomiting, which at first is the result of nausea, later becomes typically projectile in type, due not to nausea, but to reversed peristalsis. First the gastric contents are vomited; then bile-stained matter; later the contents of the upper intestine, which is brownish and sour- smelling; and in the final stages true fecal or stercoraceous vomiting may occur. Coincident with these symptoms there is absolute con- stipation, and no flatus is passed by the rectum. An enema may empty the rectum of what was already there or in the sigmoid; but after the lower bowel has been emptied, no further movement can be obtained, and in no case is there passage of flatus. In the case of an epiplocele the symptoms are the same though often less in degree, there being seldom absolute constipation or complete arrest of flatus. If the intestinal obstruction is not relieved, peritonitis will develop, with its characteristic symptoms and physical signs (p. 805). Until this event occurs the temperature is not elevated, though the pulse slowly but steadily increases in rapidity. Physical examination shows a tender, painful, and tense swelling at the site of the hernia. In the case of a large hernia long irreducible, these signs are not so apparent, but usually it is evident that the swelling is somewhat more tense and painful than before the onset of the symptoms of strangulation. In an omental hernia the swelling is boggy, rather than tense. There is no impulse in a strangulated hernia when the patient coughs. Palpation of the abdomen usually reveals rigidity of the abdominal muscles near the site of the hernia; it is a voluntary rigidity, not like that which results from peritonitis. Auscul- tation of the abdomen detects sounds of borborygmi characteristic of peristalsis; usually these peristaltic noises are exaggerated, and sometimes they may be traced up to the site of obstruction, where they are arrested with a distinct click. Diagnosis of Strangulated Hernia. — This depends on recognizing, in addition to the symptoms of intestinal obstruction, the existence of a hernia with the signs characteristic of strangulation. If the latter condition is present, it is not necessary to wait for full development of symptoms of intestinal obstruction before making a diagnosis. I STRANGULATED HERNIA 7G5 lia\c st'\or;il times found a guii^rciious patch on tlie b(nvel in cases wliore neither nausea nor vomiting had been present, althougli the strangulation had histed for from six to eiglit hours. In very fat patients it may he impossihk' to detect with certainty a very small hernia. All the usual sites of liernia should he carefully examined, and corresponding parts of the body should l)e comj)ared most dili- gently in obscure cases. A feeling of greater resistance over one hernial ring than at the corrcsj)()nding point on the other side of the body may be the only pliysical sign discernible in a case of partial enterocele (Richter's hernia); but such small herniae may become gangrenous much sooner than larger hernia\ If two hcrriicp, both irreducible, are present, it may be difficult to decide which of the two is strangulated; usually the physical signs (absence of impulse on coughing, greater tension and tenderness in the neck of the strangulated hernia) will be of more aid in such cases than the history and subjective symptoms. An irreducible hernia may be present and there may be ijeritonitis from some other cause. The distinctions between intestinal obstruc- tion and peritonitis cannot be too often insisted upon; they are detailed at p. S09. In strangulated hernia peritonitis is a late symptom, all the early signs indicating intestinal obstruction. There may be an irreducible hernia and yet there may be some other cause for intestinal obstruction: here again physical examination will show an impulse on coughing unless the hernia is strangulated; while a careful history of the case may throw much light on the diagnosis as it may indicate previous attacks of peritonitis, leaving crippling bands or adhesions as the true cause of the symptoms. If no conclusion can be reached after careful study, the surgeon should expose the hernia before proceeding to exploratory laparotomy. The vomiting of pregnancy may be confusing, if an irreducible hernia is present; but the negative physical examination of the hernia, and the fact that there is no evidence of intestinal obstruction, should be sufficient evidence of the true condition. In some cases of inguinal hernia, confusion is caused by the presence of an inflamed lymph node in the groin, and in infants by an inflamed, hydrocele of the cord. When, as often in these cases, physical examination is unsatisfactory, and the history is unknown or negative, a differentiation may be impossible. An undescended testicle need not be mistaken for a strangulated hernia if the surgeon is cautious enough to examine the scrotum before reaching a diagnosis. Treatment of Strangulated Hernia. — The object of treatment is to relieve the strangulation. This may be accomplished (1) by pushing the strangulated bowel or omentum back into the abdominal cavity by means of Taxis; or (2) by operation — dividing the constriction, inspecting the bowel, and treating it appropriately before restoring it to the abdomen. In most cases this operation may be completed by repair of the abdominal wall so as to prevent recurrence of the hernia. The physician never should leave his patient until the stran- gulation has been relieved, or until he has made arrangements for immediate surgical treatment. 76G HERNIA Taxis. — This is a term derived from tlie (ireek, and implying arrangement or adjustment. It is used in surgery in a technical sense to descril)e various manipulations by which the surgeon seeks to secure reduction of a hernia. The patient should be placed on a bed, with his shoulders and pelvis raised, so as to relax the abdominal muscles. The surgeon then surrounds the hernial orifice with the thumb and fingers of his left hand, while with the right he endeavors by very gentle but persistent compression to empty the herniated bowel of some of its gaseous and fluid contents. When this has been accom- jilished, he employs his right hand in the most gentle and ])atient kneading movements, in the attempt to make the bowel recede into the abdomen. The direction of pressure must correspond to that by which the bowel came down. Success is manifested by the bowel slipping back into the abdomen with an audible gurgle and a charac- teristic flop. If these signs are absent, e^'en though the hernia appears to have been reduced, it is most probable that this is not really the case, but that reduction in 7nass has occurred. This term implies that the contents of the sac have been pushed upward until they lie on the inner aspect of the abdominal wall, but have carried before them the neck of the sac, which is the seat of constriction; and that the hernia, still strangulated, rests between the abdominal wall and parietal peritoneum. If the symptoms of strangulation persist, operation should be done immediately. Contraindications to tJie Taxi,^. — ^(1) Taxis never should be employed if anyone else already has attempted it; because there is no telling how much damage may have been done to the gut, and in its present state even the very gentlest manipulation may rupture it or cause other disastrous consequences. (2) Taxis never should be employed in very acute cases; it is suitable only to such as begin with symptoms of incarceration or obstruction of the hernia. (3) Taxis never should be employed while the patient is anesthetized, as there is too much risk of using unjustifiable force. (4) Taxis never should be persisted in for more than fifteen minutes. Operation. — The operation for strangulated hernia is one which any medical man may be called on to perform in emergency. It is not nearly so difficult as is the taxis, and is incomparably more efficient in securing the end in view — that of relief of strangulation. If opera- tion were resorted to in every case within the first twelve hours, and with modern aseptic methods, the mortality of strangulated hernia would be only from 3 to 5 per cent., or less than half that of typhoid fever; instead of as high as that of pneumonia, or fracture of the base of the skull, as it is now, when in many cases the obstinacy of the patient or still worse the ignorance of the family physician post- pones operation until gangrene and peritonitis have developed. The mortality when operation is employed under such circumstances varies from 10 to 50 per cent., according to the constitutional resist- ance of the i)atient. If no operation is done, spontaneous cure by sloughing and formation of a fecal fistula may result in as many as 2 per cent, of cases, while OS per cent, will terminate in deatii. STh'.WCCLATKD IIERMA 7C)7 TIk" operation, wliicli is known as licniiofoiiii/ or ktldtoiiiy, consists essentially in niakinij an incision throuj;h tlie overlying structures until the neck of the sac is exposed; then the sac is opened, and the constriction causinij; stranj^nilation is divided. For this deep incision many surgeons still use Cooper's herniotome (Fig. 7()S) which has the advantages of a l)lunt ])oint which can he sli])ped under the constriction and a short cutting edge. The contents of the sac are then replaced within the abdomen if they are in good condition, and the wound is rej)aired as in an operation undertaken for the "radical cure" of hernia. If the contents of the sac are not in good condition they are treated as descrihed helow (see Treatment of Complications). Fig. 768. — C'oopor's horuiotoino. In former times, before the days of aseptic surgery, there was great danger of })eritonitis developing after such an operation, and much more stress was laid upon the employment of taxis, and even in operating many surgeons followed the method of Petit (1760), who divided extra-saccular constrictions and then reduced the hernia icithoui opcninc] the sac. But for the last twenty years at least, the taxis has been falling increasingly into disfavor; and especially since the development of methods of inducing local anesthesia, and spinal analgesia, have surgeons been more ready to resort to operation. And I am convinced that it should be clearly understood that no patients however moribund in appearance (unless in articulo mortis) should be refused the hope of recover}' which operation always affords. If the patient is too ill to endure a general anesthetic, and if no facili- ties exist for administering local or spinal anesthesia, there is no reason in the world why the operation should not be done without any anesthetic whatever. Our surgical ancestors operated thus for many generations, and in not an insignificant proportion of cases recovery followed. Treat:\iext of Complicatioxs. — As the surgeon cuts through the overlying tissues he may find that they are edematous. This may be the result of trauma inflicted during attempts at taxis, or rarely may be due to inflammation spreading from a fecal abscess in the sac. The sac usually is recognized by its transulucent and bluish appearance. Usually it is impossible, and never is it requisite for the surgeon to recognize the various layers of tissue overlying the sac. Each of the deeper layers as it appears should be cut through cautiously, as one opens the peritoneum, after raising it in forceps from the underlying structures. In this way there is very little danger of injury to the contents of the hernial sac. In most cases there is some fluid in the sac; if it is clear and limpid, it is not likely that the condition of the bowel is very bad. When the sac is opened and the constriction relieved, more of the bowel should be drawn out of the abdomen, and 768 HERNIA its condition should be carefully observed. (In serious cases the anes- thetic, if given by inhalation, may be suspended at this point in the operation.) If the bowel was merely nipped in the hernial orifice, and has fallen back into the abdomen as soon as the constriction is relieved, the surgeon never should neglect to draw it out again into the wound to ascertain its condition. The next step is the application to the bowel of hot (115° F.) sterile hot water or saline solution. The hot fluid should not be poured over the bowel with any force, but should be allowed to flow gently over the bowel so as to avoid the trauma even of a current of water. Nor should the bowel be sub- jected to massage or to irritation by gauze sponges. The bowel should be examined for its lustre, its color, and its elasticity. Though the color when first exposed may be bright red, bluish, dark blue, purple, or even black, it may return to normal after relief of the strangulation and application of hot solutions for a varying time up to half an hour. If the gut is entirely gangrenous when first seen, of course it is hope- less to expect its recuperation; but recovery may occur from any stage short of gangrene; and a patch of seeming gangrene which at first appears so large as to demand resection, may be so much dimin- ished in size by hot applications as to permit of retention of the bowel after inversion of the worst portions. If the lustre of the peritoneal coat is preserved, as a rule the color will return to the normal and the bowel will survive. If the mesenteric vessels cannot be felt pulsating the bowel will not survive. If the bowel fills out with its contained air and retains its normal cylindrical form, it is more apt to be healthy than if it has lost its resiliency and retains any indentation or crease accidentally produced during manipulation. Careful inspection should be made also of the circular constrictions on the bowel at the points of strangulation, if such constrictions exist. There may be a threatening perforation here, while the intervening portion of bowel which was not directly compressed, but had its circulation impaired only by pressure on its mesentery, may be fairly normal. If the bowel returns to its normal condition, it should be replaced, and the wound should be closed. If a suspected spot remains, it often is possible to cover it in by inverting it and suturing neighboring healthy portions of bowel over it, as indicated in the accompanying diagrams. Even though the entire lumen of the gut appears to be obstructed by the amount of its wall inverted, recovery without any untoward symptom may occur (Fig. 7(39). The sero-sero;us suture is used, as in other intestinal operations (p. 830). If the circular constriction at the point of strangulation has been very tight, it will have crushed all the coats of the bowel except the peritoneum at this point, just as if a compression forceps had been applied to the gut previous to the application of a ligature. In such circumstances the ring of constriction sometimes may be covered in by producing a partial intussusception of the bowel (Fig. 770). Onl}^ if there is actual gangrene is resection desirable; and even in such cases, if the patient's condition is very bad, or if the operator is STRANGULATED HERNIA 709 inexperienced, it will 1)0 c[uite sufficient to leave the gangrenous coil of intestine lying in the sac, after relieving the constriction, and packing sterile gau/e around the bowel, which should then be opened and drained. If the proximal (afferent) bowel is very much distended, or if the strangulation has existed a long time, it always is well to evacuate ihe rouietds of the proximal loop (wliich in such cases are regarded as highly toxic), instead of allowing these contents to pass on down through the intestinal canal, whence absorption may occur, causing increased toxemia. Fig. 70!). — Gangrenous spot on bowel (a), inverted into lumen by sutures (b). From a patient in the Episcopal Hospital. Recovery. Fig. 770. — Gangrenous area involving nearly whole circumference of bowel (a), successfully treated by producing a partial intussusception (b). Episcopal Hospital. ^Miere resection of the bowel is done the surgeon may terminate the operation either by establishing a false anus in the wound, or by completing an intestinal anastomosis. The former should be selected in all cases where a prolongation of the operation is not desirable, unless the site of resection is very high in the intestinal canal. When an anastomosis is done it may be either an end-to-end anastomosis or a lateral anastomosis (p. 833). In these cases no fur- ther prolongation of the operation is desirable, so no attempt at a "radical cure" of the hernia should be made; it is sufficient to close the wound, usually with drainage, in the simplest and most expe- ditious manner. The treatment of omentum found in the sac demands a few words of explanation. If there is no serious change in this structure, it may be replaced; but if there is any doubt about its condition, it should be 49 770 HERNIA excised, after tyiiifj it oti' where normal by a series of interlocking ligatures, below which it is cut away, leaving a sufficient stump to ensure that the ligatures will not slip. Each ligature should include no more than a pencil's thickness of the omentum, and the omentum should be excised before the ligatures are cut short, so that the sur- geon may use them to hold the omental stump in the wound for careful inspection, to make sure that hemorrhage is controlled. The omental bloodvessels have no muscular coats, and do not retract or contract and allow spontaneous cessation of bleeding. Not unfrequently the omentum protrudes in a loop, into the hernial sac (Fig. 771), and unless Fig. 771. — Loop of omentum protruding into hernial sac, but having its free end within the abdominal cavity. Complications might ensue if this free end was not drawn out before Hgating and cutting off the omentum. care is taken to pull the end of the loop out of the abdomen before its base is ligated there will be danger of its necrosing and causing peri- tonitis or obstruction later. The omentum is so seldom normal when it has been long in a hernial sac, even if not strangulated, that I believe it is much better to excise it under all circumstances, unless the con- dition of the patient is such as to render any prolongation of the operation unjustifiable. If it is restored to the abdomen it is quite likely to cause subsequent trouble either by adhesions or by favoring recurrence of the hernia (Lucas-Championniere). The after-treatment is the same as after other operations for intestinal obstruction. If the wound has not been securely repaired, the patient should be operated on after complete recovery, to obtain a radical cure; or a truss should be worn to prevent reappearance of the hernia. SPECIAL HERNI-ffi. ' Classification. — There are only three forms of hernia of frequent occurrence; all the others are rare. The most frequent form is the inguinal, which occurs in about 73 per cent, of cases; then comes the femoral, in about 18 per cent, of cases; and lastly the nmbilical, which occurs in about 8.5 per cent, of cases. This leaves about 1 per cent. EPIGASTRIC HERNIA 771 f.,r tl„. n,r,T forms (luinl.ar, „l,turat„r. ,-t,-.). 1" /Lis reckoninK Wv T ,K-isi,„ul iKTMi. is not inclu.lo,!. T„ aHor,l a persp«-tus„l tl,rsul.i;.ct to tlu. student, tlKTC is n,. nu,ro s.-rvnoablc class,h,at,on of licrniii than the follov/ing: ITeRNLE of the El'KiASTKIC REGION. 1. Diaphriiuinatio. 2. F.pi gastric. IIeunle of the Mesogastric Region. 1. WMitral 2. Incisional— These mjiy occur also m other regions. 0. I'mbilical. 4. Lumbar. Hernle of the Hypogastric Region. 1. Inguinal. 1. Indirect (or Oblique). 2. Direct. 2. Femoral or Crural. 3. Pelvic. 1. Anterior— obturator. r (1) Perineal. 2. Inferior < (2) Pudendal. t (3) Vaginal. . / (1) Ischiatic. 3. Posterior! (2) Gluteal. These various forms will now be discussed in turn. Diaphragmatic Herniah.. already been considered (p. 751). Internal Hernm is discussed in Chapter XXII. ,, Epigastric Hemia.-By this term is understood one or more sma protri'ions, usually of omentum only, occurring in or near the med a^. line of the abdomen (linea alba) between ensiform process and um- bilicus. It is a rare condition, first well studied by Terrier m 1886. A much more frequent abnormality, and one which often is mistaken for a ture hernials the protrusion of small portions of the vrep^n- toneal fat through apertures between the ^rf^^verse fibres of the sheaths of the recti muscles which go to form the linea alba Accord- ing to Tillaux (1894) it is more frequent in men. The patient com- pkins of pain, and on examination a small mass can be felt the size of a ilarble or thereabouts, and generally irreducible. It simulates an '^TrtTment.-If the application of firm pressure by adhesive plaster or an abdominal belt does not afford relief tl.e ^fy'TLZhX excised, after exposing and ligating its pedicle. If the Imea alba is carefully sutured there is not apt to be a recurrence. 772 HERNIA Ventral Hernia. — This hernia may occur in any part of the abclomi- nal wall, but does not protrude through one of the usual apertures such as the umbilicus, the inguinal or femoral canals, etc. It is a very rare form of hernia, though by many surgeons it is not distin- guished from incisional hernia (see below). The usual cause is injury resulting in partial rupture of the alxlominal muscles, from a direct blow or merely by muscular strain. In some cases no distinct history of injury can be obtained, the abdominal wall seeming to have yielded spontaneously at the site where the hernia appears (Fig. 772). No true sac exists, the parietal peritoneum merely bulging a little when the patient strains. Fig. 772. — Ventral hernia through right olJiciue muscles. Episcopal Hospital. (Dr. Neilson's case.) Under the heading of ventral hernia may be included also protru- sion due to diastasis of the recti muscles in the mid-line. A slight degree of diastasis is normal above the umbilicus, but pathological diastasis usually is seen in the hypogastric region, and occurs in women who have borne many children and who are emaciated. A similar condition is frequently seen in infants and young children, as a congenital deformity. Symptoms. — The s^^mptoms of ventral hernia are a feeling of weak- ness at the site of the protrusion, and dragging sensations within the abdomen. The diagnosis is not difficult, if the possible existence of the condition is remembered. Treatment. — Usually symptomatic relief is secured by wearing a firm abdominal belt. In children with diastasis of the recti the use of adhesive plaster strapping as advised in cases of umbilical hernia usually effects a cure. Even in adults the hernia is not liable to com- plications, but if desired the patient can secure permanent relief by an operation as for incisional hernia. Incisional Hernia. — This is much more frequent than a true ventral hernia, and receives its name from its development in the cicatrix of an operative incision. One cannot too much insist upon the impor- INCISinyAL HERNIA 11?> tauoc ol" placiiiii the incision so as to do as little (iainage as possiljle to the structures of the al)(h)niinal wail (see p. 818). Incisional hernia was nnich more t"rc([U(Mit I'ornierly when less care was taken in the repair ot" alxloniinal wounds. An incisional hernia is very rare in a clean wound which is closed completely by tier suture. If the wound is drained, a hernia is much more apt to develop. Fig. 773. — Incisioiuil hernia, in scar of operation for appendicitis .seven years ago (incision in right semilunar line). Episcopal Hospital. Fig. 774. — Incisional hernia, in scar of operation for typhoid perforation of intes- tine nine years ago (right rectus incision). Two years ago a right inguinal hernia also developed. Age thirty-six years. (Dr. Harte's case.) Episcopal Hospital. This form of hernia may be of any size, and if large may cause very great disability. Usually there is no true peritoneal sac, but the abdominal viscera lie in direct contact with fascia or skin, and almost always are closely adherent to their coverings. Owing to this fact Fig. 775. — Incisional heinia one year after operatii^n for api^endicitis (right rectus incision). Children's Hospital. there is no chance for spontaneous cure even if the hernia is kept reduced by suitable appliances. As the abdominal opening is rela- tively large, strangulation or other lesser complication is rare; though incarceration may occur if the aperture is small. The symptoms are the same as in ventral hernia. 774 HERNIA Treatment. -If the patient is healthy, operation should he clone. If this is contraindicated, an abdominal belt, as in cases of pendulous abdomen (Fig. 875), may relieve the worst symptoms. When operation is done it should be remembered that the cicatrix is usually very thin and the hernial contents adherent. The surgeon, therefore, begins by an incision at the periphery of the hernia, and opens the abdomen not directly through the old cicatrix, but through healthy tissues above or below or to one side of the hernia. Here there will be no adhe- sions to the parietal peritoneum. The hernial contents are then cautiously dissected free from the overlying abdominal wall, the cica- tricial tissue is excised, and the herniated structures reduced. In cases of very large hernia with many adhesions between the prolapsed intestines and omentum it is not desirable to separate these more than is required to free the different layers of the abdominal wall. Redundant or diseased omentum should be excised. The various layers of the abdominal wall, especially the aponeuroses, should be dissected free, exposing enough of each for accurate suture, and if possible for overlapping. Then the wound should be repaired as a recent abdominal incision (p. 821). The most important layer of the abdominal wall to suture accurately is the anterior sheath of the rectus or the aponeurosis of the external oblique. Hemostasis should be absolute, and the wound should not be drained. The patient should remain in bed for at least three weeks, and if the hernia was large should wear an abdominal belt and avoid straining efforts for a year after operation. Bartlett (1903) and other surgeons have implanted silver wire filigree in these wounds, with a view of rendering them stronger. Recent experience has shown that free flaps of fascia lata can be transplanted to supply the defect. Umbilical Hernia. — This is a frequent affection, especially in infants and stout adults past middle life. Three forms are to be distinguished, the Congenital, the Infantile, and the Adult. Congenital Umbilical Hernia is rare, occurring once in five or six thousand births. It is classed as embryonic and fetal. The former is due to failure of development of the abdominal wall, and the hernia, or rather eventration, may be very extensive, containing beside intestine also stomach, liver, heart, etc. The fetal variety develops after the third month of intra-uterine life, and the sac is lined by peritoneum and seldom is very large. Infants with large embryonic hernia usually are stillborn, or die so soon after birth as to offer little chance for repair of the defect by surgical means. The smaller fetal hernia usually is covered only by a translucent membrane through which the herniated viscera can be seen. Other malformations, espe- cially of the bladder or rectum, may be present. Treatment. — ^The hernia should be repaired by operation so soon as possible. The general mortality is about 30 per cent., but is less after operation done on the first day of life than later. Umbilical Hernia in Infants and Children is very frequent. It develops at any time after complete cicatrization of the navel, and seldom UMBILICAL UKHNIA i <•) appears fir.st after the close of the seeuiicl year of life. I'he hernia seldom is very large, is covered by normal skin, and usually appears not directly under the umbilical cicatrix, but slightly above and to one siile. Pressure by a finger reduces the hernia easily, and when the child cries or strains it becomes larger and more tense (Fig. TTb). Treatment. — If the hernia is small and the child is young, there is some chance of cure without operation. With the child lying down, one end of a strip of adhesive i)laster, about two inches wide is fixed in one lumbar region; then the surgeon draws the opposite side of the belly forward, so as to form a longitudinal fold in the region of the Fig. 776. rachitic negro Hospital. Umbilical hernia in a boy. Children's Fig. 777. — Result of operation for umbilical hernia with preservation of the navel. Children's Hospital. linea alba. The adhesive plaster is then drawn across the relaxed belly and is tightly applied to the loin on the other side. It is well to reinforce this first strip by one or two others. It is better not to place a button, or a coin, or pad, or anything else over the hernia, as these tend to keep open the hernial ring. The adhesive plaster should be renewed about once a week, or as often as it comes loose. Care must be taken to keep the hernia reduced by the finger while the plaster is being changed. Attention is necessary to prevent excoria- tions of the skin. If the plaster is applied too tightly it may encourage the development of inguinal hernia. If this method of strapping an 776 HERNIA umbilical hernia is faithfully continued for a year, a cure will result in a large number of cases if the hernia is small and of short duration. If no improvement is apparent within four or six months, operation probably will be necessary. Operation for infantile umbilical hernia is best done after the child is two years old. This will allow a fair trial of conservative treatment. I think it is well in children, especially in boys who are exposed more than girls to ridicule for any abnormality, to do an operation which permits preservation of the riavel, as advised by Stone. I make a semi- lunar incision, below the umbilicus, in the direction of the folds of the skin, and turn this skin flap upward, exposing the hernial ring, which is treated as in adults; when the skin flap is replaced, the patient's aspect is quite normal (Fig. 777). Fig. 778. — Umbilical hernia in adult. Age fifty-two years; duration two years. Episcopal Hospital. Umbilical Hernia in Adults. — This may be a sequel or recurrence of the infantile form, or may dexelop first in adult life. It is more fre- quent in women, being predisposed to by repeated pregnancies. As in infants and children, the protrusion usually occurs slightly above the umbilical cicatrix. Omentum is almost always present in the sac, and generally becomes adherent, rendering the hernia irreducible at least in part. When the hernia is allowed to grow large, it becomes pendulous (Fig. 778), and usually contains transverse colon and often small intestine also. Incarceration is frequent, and strangulation not unusual. Strangulation often is intra-saccular, a coil of gut being caught in the matted and hypertrophied omentum. The coverings of the hernia are skin, subcutaneous fat, a thin layer of fascia, pre- peritoneal fat, and peritoneum; the latter forms the sac, which is acquired, not congenital. The pressure of the hernia causes atrophy of the tissues overlying it, and the contents of the sac usually lie very close to the skin, at least over the fundus of the sac. In most cases there is also considerable diastasis of the recti muscles, both above and below the ring. UMBILICAL HERNIA 777 Treatment. — The best treiitnient is hy operution. Before tliis is attempted, however, it is very important to secure reduction of as mucli of the liernia as is ])()ssil)le, by tlie means described at p. 7()(). A transverse incision is made, outlining an ellipse of the redundant skin, including the umbilicus. This incision should extend from one semilunar line to the other, and in very fat patients may have to be even longer. This incision exposes the anterior sheaths of the recti muscles on all sides of the hernial ring, and at some distance from it. The fat is then dissected off the aponeurosis up to the borders of the ring, and at this point the sac is cautiously opened, with the usual precautions against wounding its contents. This is very hard to avoid, if an attempt is made to open the sac at its fundus. The sac is then cut away with scissors at the margins of the hernial ring, on the finger as a guide, and the parietal peritoneum as cut is caught in clamps to prevent it from retracting out of sight. The reducible con- tents of the sac are then replaced in the abdomen. I^sually a good deal of omentum has to be excised; this should be done with the precau- tions recommended at p. 769. The skin containing the umbilicus, circumscribed by the original incision is removed in one piece with the hernial sac {Omphalectomy). When all the hernial contents have been replaced, a gauze pack is inserted to plug the opening and keep them from protruding again. The next step is closure of the hernial ring: a transverse incision is made outward for about one inch from the hernial ring through the anterior sheath of each rectus muscle. Usually there is diastasis of these muscles, and for a distance of one inch or more on each side of the mid-line the anterior and posterior sheaths of the recti may be in contact. The anterior sheaths alone are to be incised, and are dissected upward and downward until a flap of this strong aponeurosis is formed both above and below the hernial open- ing. The margins of the neck of the hernial sac (parietal peritoneum), still caught in forceps, are next to be closed with sutures. This may be accomplished by applying a purse-string (p. 829) if the ring is small; but if it is large it is better to use interrupted sutures. The sutures should include also the transversalis fascia and the posterior sheaths of the recti muscles. Before the last suture is tied the gauze pack is removed. The peritoneal cavity being thus closed, the surgeon catches in Allis forceps the free margins of his aponeurotic flaps already formed from the anterior sheaths of the recti muscles. These flaps are then overlapped, the lower one being pulled up between the upper flap and the deeper structures, and they are sutured together by interrupted mattress sutures of chromic catgut, as indicated in Fig. 779. The free margin of the upper flap may then be sutured to the superficial surface of the anterior rectal sheaths. Transverse suture of the wound in repair of umbilical hernia is preferable to longitudinal suture because patients with umbilical hernia usually have quite a pendulous abdomen, and there is much more slack in the tissues and less tension on the sutures if transverse suture is adopted. Frequently it is very difficult if not impossible to 778 HEHMA liring together the edges of the recti by a longitudinal suture, because of their diastasis; but if the transverse suture with overlapping is employed the approximation of the recti is unnecessary. The principle of overlapping fascial layers in the repair of hernia, first introduced in 1881 by Lucas-Championniere, was adopted by W. J. Mayo (1899) in the case of umbilical hernia, and the operation as above described is known by his name. He has since adopted modifications of the technique introduced by Ochsner: no attempt is made to suture the neck of the sac separately, nor are transverse incisions made in the rectus sheaths for the purpose of forming fascial flaps. The opening in the abdomen is closed simply by three mattress sutures so intro- duced as to draw its lower margin well up beneath its upper. I have Fig. 779. — Radical repair of umbilical hernia. The parietal peritoneum has been sutured, and the lower aponeurotic flap (anterior sheaths of the recti muscles) is being drawn up underneath the upper flap by means of mattress sutures. always used the original method, and believe it is preferable except where the hernial orifice is quite small. The patient should be confined to bed at least for three weeks; and if the hernia was very large or the abdomen very pendulous, an abdominal belt should be v.'orn for several months. Recurrence is very unusual. Strangulated Umbilical Hernia. — This is a very serious condition; the patient frequently is old, feeble, asthmatic, fat, and arterio- sclerotic. The hernia in most cases is already irreducible; strangula- tion usually begins with symptoms of incarceration, and the develop- ment of complete strangulation is difficult to recognize, owing to the frequency of intra-saccular strangulation. Taxis should not be per- sisted in unless the patient absolutely refuses operation. Operation usually is too long delayed. When done, no attempt should be made INGUINAL HERNIA 770 to coinplt'tf tin- procrdiirc l)y ri'pair (if tlif licriiial orifice if tlit- licriiia has been lon^ irreducible, or if the patient's condition is bad. It is sufficient to relieve tlie strangulation, and the herniated structures may be left adherent to the sac, and should not be reduced. Lumbar Hernia. — This is (piite rare. The protrusion occurs through I'etits triangle,^ which is bounded below by the crest of the ilium, in front by the external oblique and behind by the latissimuss dorsi nniscle. The fioor of this triangular space is formed l)y the internal oi)li(lue muscle or its posterior ai)oneurosis, whicli is continuous and identical with the lumbar aponeurosis, with which the transversalis muscle and transversalis fascia are here fused (Fig. 916). The cover- ings of the hernia are skin, sui)erficial fascia, lumbar aponeurosis (or internal ol)lique), ])reperitoneal fat, and ])eritoneum. Most of the cases of lumbar hernia on record have been either con- genital (probably due to abnormal size of Petit's triangle), or the result of trauma. The condition presents the usual symptoms and physical signs of a reducible hernia (p. 756), and must be distinguished from a cold abscess, as well as from a lipoma. There is no distinct neck to the sac. Strangulation is unusual. Treatment. — If the patient wears a well-fitting truss for a \ear or more, there is fair probability that a small hernia may cease to pro- trude. In most cases, however, operative treatment is preferable. This consists in dissecting out the layers of the abdominal wall, and overlapping them by sutm"e whenever this is possible. Dowd (1907) turned up a flap from the fascia lata covering the gluteal region, to aid in closure of the opening. Inguinal Hernia. — Of the three usual forms of hernia, inguinal, femoral, and umbilical, inguinal hernia is by far the most frequent. It comprises a.bout three-fourths of all cases of hernia, and is much more frequent in men than in women. In males, 9() per cent, of hernias are inguinal, about 2.5 per cent, are femoral, and only 1 per cent, are umbilical. In females, 50 per cent, are inguinal, 33 per cent, are femoral, and 16 per cent, are umbilical (De Garmo). Nomenclature. — If the hernia emerges from the peritoneal cavity at the internal abdominal ring, traverses the inguinal canal, and ap- pears at the external abdominal ring, it is called an indireci or oblique inguinal hernia. If it passes directly through the abdominal wall on the median side of the deep epigastric artery, and thus appears at the external ring without traversing the inguinal canal, it is called a direct inguinal hernia. This is much rarer than the indirect form. If the hernia remains above the brim of the pelvis, it is called an incomplete inguinal hernia, or a bubonocele; if it descends beyond the brim of the pelvis it is called a complete inguinal hernia. A complete inguinal hernia in the male enters the scrotum and is termed a scrotal hernia; in the female it enters the labium majus and is called a labial hernia (this should not be confused with a pudendal hernia, p. 800). 1 Lumbar hernia was first described by J. L. Petit in 1783. rso HERXIA Oblique Inguinal Hernia. — Inguinal hernia is more frequent in the male because of the greater size of the inguinal canal and because of the existence of the vaginal process of peritoneum which accompanies the testicle in its descent into the scrotum. These facts account also Fig. 780. — Incomplete obliteration of the funicular process of peritoneum, just above the testicle. Found at operation on a patient aged thirty-two years; duration of hernia sixteen years. Episcopal Hos- pital. Fig. 781. — Ordinary adult type of in- guino-scrotal hernia: fundus of sac separate from testicle, and easily enu- cleated. Hernia usually slowly de- veloped. for the greater frequency of oblique than of direct inguinal hernia. It is gradually coming to be recognized, largely owing to the teaching of Hamilton Russell (since 1899), and of R. W. ^Murray, that most Fig. 782. — Hernia into patulous pro- cessus vaginalis: there is no separate tunica vaginalis. So-called "congenital hernia. " A hernia of sudden formation. Fig. 78.3. — Hernia into funicular pro- cess: fundus of sac adherent to tunica vaginalis. So-called "infantile hernia." A hernia of sudden formation. cases of hernia are due to the existence of a preformed sac. The proba- bility of the existence of such a sac is greatest in the inguinal region; and formerly it was the custom in describing oblique inguinal hernia to lav great stress on the different varieties of sac which might be INGUINAL HERNIA 781 present, aeeordiiig to tlie stage of development which had been reached by the vaginal process of peritoneum during fetal Hfe. These dis- tinctions have little more than academic interest; but a reference to the acconii)an\ int,^ illustrations will explain the five forms which may be encountered. Occasionally iiicoiiijjlrir ohlitenifidn of the Jiininildr process occurs at one or more i)oints, forming fibrous bands or strictures in the serous sac (Fig. 780) ; this accounts for cases of bilocular hydro- cele (p. 1000), and is of some imi)ortance because strangulation may occur at any of these i)oints, as well as at the neck of the hernial sac. The fact of greatest imi)ortancc to bear in mind is that it is the exist- ence of a preformed sac which predisposes to development of hernia, and that it is the extirpation of tJie sac which is the most important step (especially in cliildren and young adults) in the operation for the cure of hernia. A. II. Ferguson pointed out that in some patients the Fig. 784. — -Hernia encysted into the tunica vaginalis. The "encysted hernia of Sir Astley Copper." Funicular process closed only at the internal ring. An ac- quired hernia of slow formation. Fig. 78.5. — Hernia encysted between tunica vaginalis and testicle. "Encj^sted hernia of Hey, of Leeds." Due to same congenital defect as Fig. 784, but parietal peritoneum has yielded just posterior to upper obliterated end of funicular process. internal oblique muscle does not have an origin from Poupart's ligament, as is normally the case, and that this renders the region of the internal abdominal ring very weak. Apart from these anatomical factors, the predisposing and exciting causes of inguinal hernia are the same as those of hernia in general (p. 754). If the hernia is present at birth it is one usually described as congenital (Fig. 782); but of course a "congenital" sac may be present but no hernia develop until adult life. If the hernia appears at any time after birth, and is of sudden formation, it is probable that there was a preformed sac, and that the sudden appearance of the hernia is caused by muscular effort forcing some of the abdominal contents into this sac (Fig. 783.) If the hernia is of slow formation, which is rare except in adults, it is still possible that a small preformed sac may have existed. 782 HERNIA If the hernia occurs into a sac formed by the patulous vaginal process of peritoneum (Fig. 782), whether the hernia is present at birth, appears during infancy or childhood, or does not appear until Fig. 76(5. — Kight oblique inguino- scrotal hernia. Congenital sac, but hernia developed in adult life. Outline of testi- cle obscured. (See Fig. 782.) Episcopal Hospital. Fig. 7n7. — Right oblique inguino- scrotal hernia, funicular type (infan- tile). Age sixteen years. Outline of testicle distinct from that of hernia. (See Fig. 783.) Episcopal Hospital. late adult life, the contents of the hernia ivill obscure the outline of the testicle (Fig. 786). If, however, the testicle has its own tunica vagi- -:^- FiG. 788. — Right oblique inguino-scrotal hernia; age sixteen years; slowly acquired three years ago. McBurney incision for appendicitis eight years ago. (See p. 754.) Outline of testicle distinct from that of hernia. (See Figs. 781 and 791.) Episcopal Hospital. nalis (Figs. 781 and 783), the hernia and the testicle can he perceived as separate swellings in the scrotum (Figs. 787 and 788). This distinction is of some clinical importance, when operative treatment is under- INGUINAL HERNIA 783 takfii (\). "Sltj. In all cast's, with wry tVw (.'xc('j)ti()iis, the hernia lies in front of the spermatic cord, and even if the hernia is irreducible, the cord usually can be palpated behind it. Symptoms and Diacnosis. — An ()l)li([U(' inermatic cord (Fig. 795). By a little skilful dry dissection the end of the finger can be passed entirely through, beneath these structures from the lower to the upper side of the wound. Holding these structures upon the left index finger, the sur- geon strips its various coverings off the hernial sac by wiping them away with gauze or by the use of dissecting forceps. As little cutting as possible should be done, as this increases' bleeding. The names of these deep coverings of the hernia (intercolumnar fascia, i. e., external oblique; cremasteric fascia, i. e., internal oblique, and fascia propria i. e., transversalis fascia, have little more than academic interest. INGUINAL HERNIA 789 The sac is least adlicrcMit to surroiiiKliii},^ structures in the upper part of the iufiuinal eaual, and it is best to isuhite it here first. When tlie sac is finally bared, it may be opened, and its contents reduced. Then with one fin<;er inside the sac, the surj^eon proceeds to complete its enucleation from the surroundinff tissues.' The sac sac is separated from the cord, and the dissection is continued upward to the internal ring, until parictdl pcrituneuni is reached. This is known by the presence of pre-peritoneal fat, and by the peritoneum becoming whiter, denser, and more fibrous; and the operator should not be satisfied until such peritoneum has been reached. If he desists before parietal i)erit()neum is reached he will leave the upper part of the sac behind, in the form of a pouch, which will predispose to recurrence. The operation is not always easy. When the parietal peritoneum has Fic. 795. — Operation for inguinal hernia: the inguinal canal has been exposed by an incision through the aponeurosis of the external oblique. The finger is passed down close to Poupart's ligament and hooks up all the structures in the canal. been exposed, the neck of the sac is closed by a purse-string suture, or if large by continuous suture, as in the case of any abdominal wound. It is not sufficient merely to ligate the sac as one ligates an artery; such a ligature is very apt to slip off the neck of the sac. When the neck of the sac has thus been securely sutured, the sac is cut away, but the ends of the suture are left long; the neck is now allowed to recede into the upper angle of the wound, and is carefully inspected for bleeding; if this is found the neck of the sac is drawn again into full view by the attached suture, and the bleeding-point is ligated or 1 If the sac is of the "congenital" type (Fig. 782), its complete enucleation is impossible. The fundus should be left attached to the testicle, and may be sutured, to form a tunica vaginalis. If very much of the fundus is left a secondary hydrocele may form. 790 HERNIA controlled by an additional suture. When it has been ascertained that there is no bleeding, the ends of the suture are cut short, and the surgeon proceeds to close the inguinal canal. The spermatic cord is held out of the way, and the first row of deep sutures is introduced. These sutures are to approximate the arching fibres of the internal oblique and the conjoined tendon to the inner shelving margin of Poupart's ligament, so as to form a new floor to the inguinal canal, upon which the transplanted cord is to lie. This is the essential feature of Bassini's operation. In passing these sutures there is considerable danger of wounding the femoral vessels, especially the vein, beneath Poupart's ligament. These are mattress sutures of chromic catgut (No. 2 or Xo. 3). The first suture is passed at the upper end of the inguinal canal just below the internal ring. The round-pointed curved needle is entered from the superficial aspect of Fig. 796. — Operation for inguinal hernia: suturing the arching fibres of the internal oblique (beneath the cord) to Poupart's ligament. Poupart's ligament (Fig. 796), and emerges (on the surgeon's index finger as a guide) on the deep and shelving border of this ligament in the inguinal canal. It is better to prick your finger than to injiu-e the femoral vein. The needle is then passed beneath the spermatic cord, and takes a firm hold of the internal oblique, passing through it from below upward. The course of the needle is then reversed, passing first through the internal oblique from above downward, then across the inguinal canal beneath the cord, and finally through Poupart's ligament from within outward, to emerge about half a centimeter from its original point of entrance. This completes the first mattress suture. Usually three or four other similar sutures are required, the last sutures drawing the conjoined tendon down against the lower and inner end of Poupart's ligament. If the upper end of the canal seems weak, it is well to pass the first suture through Poupart's IXariXAL IIEliSIA 701 Iii;;tiiu'iit and tlic iiitcriial <>l)li(|ii(' just on the lateral (flank) side of the internal rin^. By j)assin,u all these deep sutures as deserihed, the knots are hrouulit entirely outside the inj^Miinal canal, 'i'his is an advantajije. The spermatie cord is now replaced on the superficial surface of the internal ohlifpie, and the cut niarj^ins of the external oblique aponeu- rosis are then sutured, over the cord, witli a contiiuious suture (the second row of deep sutures) from above downward, leaving an opening below (the new external ring) just large enough to transmit the cord (Fig. 7i)7). The skin wound is then closed in the usual way. The patient slionld remain in bed two weeks, and if the hernia was large, or if more than one hernia was operated on, for three weeks or longer. Fig. 797. — Operation for inguinal hernia: the aponeurosis of the external oblique is sutured over the cord. In women the operation is simpler, since there is no cord in the way. The canal may be completel}' closed, the round ligament being included in the sutures. In infants the use of a truss for a year or more will cure a small hernia in a fair proportion of cases — De Garmo says in 95 per cent. But this means that the truss fits, that it is changed from time to time as the child grows, that the patient is under constant surgical super- vision, and that the truss is employed with all the precautions enumer- ated at page 759. Unless these conditions are fulfilled, and they rarely are, a cure need not be expected. But, as a rule, it is not desir- able, though perfectly possible, to resort to operation on a child until it has learned to control its bladder and bowels. The youngest patient I have operated on was a boy, six weeks old, with strangulated hernia ; he was not confined to bed after the operation, and did perfectly well. In young children complete extirpation of the sac is sufficient to ensure against recurrence; it is not necessary to transplant the cord, and if it is short it may be impossible to do so. If the inguinal canal seems 792 HERXIA weak, the other steps of the operation are the same as in the Bassini operation. This form of operation, without transplanting the cord, was employed also in adults by A. H. Ferguson (1899), and is known as Ferguson's method. Direct Inguinal Hernia. — This hernia is one which protrudes through the abdominal wall on the median side of the deep epigastric artery, just to the outer side of the spine of the pubis, and directly behind the external abdominal ring. This is the space known as Hesselbach's triangle. Direct hernia is seen about once in every 30 to 40 cases of indirect inguinal hernia. It is least rare in adults and occurs oftener in men than in women. It is a hernia of slow formation, and there is no well defined neck to the sac. In most cases it may be recognized at a glance (Fig. 798). Strangulation is very unusual. It is distin- guished from oblique inguinal hernia by the fact that when it has been reduced, pressure over the internal abdominal ring does not prevent its reappear- ance. It should not be for- gotten that a large indirect inguinoscrotal hernia may cause the position of the internal ab- dominal ring to shift until it lies directly behind the external ring; but a direct hernia never descends far into the scrotum. Sometimes when the hernia is reduced, it is possible to palpate the deep epigastric artery on the lateral margin of the hernial orifice. If there is any doubt about the nature of the hernia, it probably is an indirect inguinal hernia. A direct hernia usually protrudes tlirough the conjoined tendon, which is carried forward as one of its coverings. Occasionally, how- ever, it passes to the outer side of the conjoined tendon. In most cases the spermatic cord lies on the outer side of the sac. Rare Forms of Direct Inguinal Hernia. — Sometimes the sac of a direct inguinal hernia occupies (1) a properitoneal position near the bladder; or after protruding tlirough the conjoined tendon on the median side of the obliterated umbilical vein, it may lie (2) between the conjoined tendon and the external oblique aponeurosis, or (3) in a subcutaneous position in front of the external oblique aponeurosis. For these rare varieties of direct inguinal hernia Reich, in 1909, proposed the name of Supravesical Hernia. He collected 16 cases of the first variety, which he calls internal supravesical hernia; and 26 cases of the second and third varieties, which he terms external supravesical hernia. Fig. 79S. — Double direct inguinal hernia, age sixty-eight years; duration thirty j-ears. Of slow onset, from constant straining in urination. Has strictures of urethra, and enlarged prostate. Operation on hemiae eontraindicated until urinarj- obstruction is relieved. Episcopal Hospital. FEMORAL HERNIA 793 Treatment of Direct Inguinal Hernia. — If a truss is used, it must ha\o a liir^f i)a(l, as the hernia is diflieult to eoutrol. l{ej)air of the defect hy ()i)eration is also more difhcult and is less sure in preventing recurrence than in indirect inj,minal liernia. The parts are exposed in the same way, and the sac is isolated. In doing this the surgeon should remember that the bladder frequently protrudes into Ilessel- baeh's triangle, and that its extraperitoneal surface is with difficulty distinguished from preperitoneal fat. Any fatty mass toward the median side of the liernial orifice should be avoided. When the sac has been opened and its contents have been reduced, it will be found that an opening is left which it is difhcult to suture firmly, owing to the relaxed and atrophied condition of the various layers of the afxlomi- nal wall. After the parietal peritoneum has been sutured, the inter- nal oblique and conjoined tendon should be drawn down if possible and sutured to Poupart's ligament, underneath the spermatic cord, as in the Bdsshii operation (p. 787). In cases where the internal oblicjue and conjoined tendon are very weak, the median reflected flap of the external oblique aponeurosis may be included in the sutures with them, and be drawn down and sutured to Poupart's ligament beneath the spermatic c6rd; then the lateral reflected flap of the external oblique is sutured over the cord (E. WyJlys Andrews, 1S95). If the cremaster is well developed it may be employed as an additional layer in suturing the canal. Another plan may be adopted where the conjoined tendon is so thin that it will not hold the sutures; an incision is made through the transversalis fascia along the lateral border of the conjoined tendon, raising it and the anterior sheath of the rectus off this muscle, whose fibres are then drawn over and sutured to Poupart's ligament {Bloodgood, 1898). When, as is often the case, the sac is blended with the much relaxed overlying structures, no attempt should be made to separate them, but G. G. Davis's operation (1905) should be employed: these blended tissues are divided trans- versely, and are overlapped from above downward, much as in Mayo's operation for umbilical hernia (p. 778). This gives very satisfactory closure. The use of silver filigree or of a free fascial flap, as noted at p. 774, may be desirable in some cases. However the deeper structures are sutured, the skin is closed in the usual way, and after-treatment is conducted as after operations for indirect inguinal hernia. Femoral Hernia. — Femoral or Crural Hernia has also been termed merocele. The hernia protrudes through the femoral canal, beneath Poupart's ligament, on the median side of the femoral vein. As already noted, it is commoner in women than in men, especially in w^omen after the menopause. In childhood it is rare. Though in most cases there is a preformed sac, this may not always be a congenital deformity,^ but may be a traction diverticulum probably due to the 1 According to Lockwood, a congenital sac in the femoral canal is to be attrib- uted to traction by aberrant strands of the gubenernaculum testis. 794 HERXIA fact tliat some of the preperitoneal fat is forcecl into the femoral canal and gradually draws the peritoneum after it. Such a sac may exist for many years before a hernia forms; Murray found this condition in 48 out of 200 cadavers. Most of the femoral hernice I have seen have been of sudden formation, clearly indicatino; the previous existence of a sac. As the hernia develops, it carries before it preperitoneal fat (septum crurale) and transversalis fascia (crural sheath). While still in the femoral canal it is known as an incomplefe femoral Jiernia. Increasing in size, it leaves the femoral canal, causes bulging of the criijriform fascia, and curves upward over the falciform process of fascia lata, and lies beneath the skin of the groin {complete femoral hernia). It seldom grows very large. The only contents of the sac often is omentum, but neither this nor intestine is likely to become irreducible without becoming at the same instant strangulated. Strangulation probably is more frequent in femoral than in any other form of hernia, and gangrene occurs more rapidly, owing to the sharp margins of the femoral canal. Small intestine is much more frequently present in the sac than the colon, but the cecum sometimes is found; A. C. Wood (190(3) has collected 100 cases in which the \ermiform appendix was the only structure in the sac. Rare Forms of Femoral Hernia. — The sac of a femoral hernia may have one or more diverticula, and such cases have been described as sepa- rate forms of femoral hernia: there are recognized (1) a diverticulum through the cribriform fascia, or hernia of Hesselbach (1816); (2) a diverticulum through the superficial fascia, or hernia of Cooper (1807); (3) a properitoneal diverticulum, or hernia of Tessier (1834). A more frequent, but still very rare variety, is called a pectineal hernia, or hernia of Cloquet (1814); in this the sac passes from the femoral ring between the pectineus muscle and its sheath, instead of anterior to the latter as in the usual form; if large the sac may extend outward beneath the femoral vessels. Ulrichs (1911) refers to 15 cases of this variety of femoral hernia which was well studied in 1907, by Dege. This hernia is to be distinguished from another rare variety, in which the sac enters the sheath of the femoral vessels, and passes into the thigh behind them (hernia retrovascularis). There have been recorded also a few cases of femoral hernia external to the femoral vessels, between the ilio-pectineal ligament and the femoral artery (hernia of Partridge, 1846). A hernia through an opening in Gimbernat's ligament was described first by Laugier (1833) and is known by his name; it is on the median side of the obliterated umbilical artery. Diagnosis. — A femoral hernia is to be. distinguished from other forms of hernia, from enlarged lymph nodes, from subcutaneous lipoma, from varices of the saphenous vein, and from psoas abscess. 1. An inguinal hernia appears first above Poupart's ligament, and can be retained within the abdomen, after reduction, by pressure over the inguinal canal. A femoral hernia always makes its first appear- ance below Poupart's ligament, and it will not be retained within the FEMORAL HERNIA 795 abdoinon if pressure is made only over the inguinal canal. If the hernia is irredueihle the (hajiiiosis is more (hflicMlt; hut if an inia|,Mnary line is drawn from tlie spine of the ])uhis to the anterior superior spine of the ihum, it is safe to say that a liernia wliose eiiief hulk lies below that line (which corresponds to Poupart's ligament) is a femoral hernia (Fiij:. ~!>5I). Fig. 799. — Right femoral hernia. Episcopal Hospital. 2. If an obturator hernia is present, the femoral canal will be empty, which is never the case if a femoral hernia exists. 3. In femoral adenitis the swelling may occur over the femoral canal, but it transmits no impulse on coughing; moreover, it presents signs of inflammation and a primary source of infection usually can be found. But as a strangulated femoral hernia may be present behind inflamed lymph nodes, it is safer to operate in cases of doubt. The same is true in cases of fatty or other tumors overlying the femoral canal. 4. A varicosity of the long saphenous vein may protrude over the femoral canal. It transmits an impulse when the patient coughs, but though, like a hernia, it disappears when the patient lies down, its reduction is not attended by gurgling, nor when the patient stands up will its reappearance be prevented by pressure over the femoral canal. 5. A psoas abscess is secondary to tuberculosis of the spine, which usually may be detected by proper examination. When the abscess descends below Poupart's ligament it usually appears on the outer side of the femoral vessels. Though it may transmit an impulse on coughing, and may be reducible, this reduction is not attended bj^ the gurgling so characteristic of hernia. Treatment of Femoral Hernia. — The use of a truss is unsatisfactory even in retaining the hernia within the abdomen, as it is impossible to obliterate the femoral canal ; the most that a truss can do is to close its lower (crural) opening. No cure wdthout operation need be antici- pated; and in no form of hernia is a cure so necessary, owing to the great frequency wath which strangulation occurs. 1. The usual operation is done b}' the femoral route. The skin incision may be straight, in the long axis of the body, directly over the 796 HERNIA femoral canal, or a flap may be outlined, convex outward, so that the line of skin sutures will be far removed from the genitalia (Fig. SOO). The incision should commence well above Poupart's ligament, and should expose also the fascia lata and cribriform fascia over the upper part of Scarpa's triangle. Care should be taken not to wound the long saphenous vein. When the skin and subcutaneous tissues have been reflected, the sharp margin of the falciform process of the fascia lata is to be located. Beneath this the femoral artery will be felt pulsating, and to the median side of this is the femoral vein which is in constant danger of injury. On the median side of the wound the surgeon should identify the pectineus muscle and its fascia. Then the sac may be opened. If the hernia is large and irreducible, which is seldom the case, it may be impossible to identify these various structures until the sac has been opened and its contents reduced. Fig. 800. — Incision for femoral hernia: a a', for the inguinal method; b b', longi- tudinal incision for the crural method; c c', flap incision for the crural method. Under such circumstances the operator must cut down layer by layer until the sac is opened. It is seldom possible to identify the various coverings of the hernia. The omentum in an irreducible femoral hernia nearly always requires to be excised in entirety. When the contents of the sac have been reduced, the sac must be traced up into the femoral canal under Poupart's ligament until parietal peritoneum is reached. This is known by its being whiter, denser, and more fibrous than the walls of the hernial sac. The opening in the parietal peritoneum is then closed with a purse-string suture, and the sac is cut away, with the usual precautions against overlooking hemorrhage from the stump (p. 789). P>om recent observations (Ochsner) it seems probable in most cases of femoral hernia, except where the femoral canal, is widely dilated, that accurate suture of the parietal peritoneum is a sufficient preventative of recurrence, even without any attempt to close FEMORAL HERNIA 71)7 tlio tViiioral fjiiial hy suture. Hut in most cases it is not wry (iiflicuit to insert one or more sutures so as to obliterate the canal. The needle (curved and round ])()inted), threaded with cliromic catj::ut, is entered on the superficial surface of I'oupart's li«,Mnient, close to the femoral vein, and is made to emerge in the femoral canal, catching some of the fihres of the sheath of the femoral vein if possible to do this without puncturing the vein. The needle is again gripped in the needle-holder, and is passed trans\-crscly inward, taking a firm hold of the pectineal fascia and underlying muscle, and is again grii)ped in the needle-iiolder. The needle is then passed through Poupart's ligament from below upward, near its inner end, and emerges finally near its original point of entrance on the superficial aspect of Poupart's ligament. This completes the first purse-string suture of the femoral canal (Fig. (SOI). If there is room, a second similar suture may be passed nearer the lower Fig. 801. — Crural operation for femoral hernia: closing the femoral canal. (crural) orifice of the femoral canal. When these sutures are tied, Poupart's ligament is pulled down against the pectineal fascia, and the femoral canal is closed. The needle always should be introduced first on the side of the canal where the femoral vein lies, as there is thus less danger of injury to this important structure. The skin wound is then closed in the usual \vay. 2. The inguinal route for operation in cases of femoral hernia, intro- duced, in 1892, by Ruggi, does not seem to have been employed much in this country, though it possesses many advantages, which I shall mention after briefly describing the operation. The skin incision is the same as in the operation for inguinal hernia (Fig. 800, a a'), and the external oblique is divided, freely exposing the inguinal canal. The lower border of the internal oblique and the conjoined tendon (with the spermatic cord or round ligament) are then pulled upward and toward 798 HERXIA the median line by a retractor, drawint; the transversalis fascia tense, and exposing the superficial aspect of Hesselbach's triangle — bounded below by Poupart's ligament, internally by the conjoined tendon, and on the outer side by the deep epigastric artery (Fig. 802) . The Fig. 802. — Inguinal operation for right femoral hernia: the aponeurosis of the external oblique has been divided, exposing the inguinal canal. The transversalis fascia has been divided, exposing the gac of the hernia entering the femoral ring. trans\'ersalis fascia is then incised on the inner side of, and parallel to, the deep epigastric vessels. This at once exposes the pouch of peritoneum, as it enters the upper (abdominal) orifice of the femoral canal, to form the femoral hernia. It lies just to the median side of the external iliac vein, in full \iew. The hernial sac is then drawn out Fig. 803. — Inguinal operation for right femoral hernia: the sac has been removed and the parietal peritoneum sutured; Poupart's ligament is now being sutured to Cooper's ligament. Gimbernat's ligament in full view. of the femoral canal, and into the inguinal wound. It is opened and its contents are reduced. It is then easy to close by suture the opening in the parietal peritoneum well above the neck of the sac. These steps having been accomplished, the siu"geon may insert a purse-string OBrURATOR HERNIA 79U suture iu the IVnioriil caual, precisely as in tlie erural method of operation, except that the steps of this suturing are under better control of the eye. i'oupart's ligament is pulled down by the sutures against Cooper's ligament, firmly closing the femoral canal at its abdominal opening (Fig. Hi)'^). The internal oblique and conjoined tendon arc then allowed to fall back in place; Parlavecchio and Dujarier suture them to Cooper's ligament, over the sj)ermatic cord. If tiu> inguinal canal appears weak they may be sutured beneath the cord either to Cooper's or to Poupart's ligament. The operation is then concluded, as in cases of indirect inguinal hernia. I ha\e cmployetl this inguinal method for the treatment of femoral hernia for a number of years, and regard it as superior in every way to the femoral route. It is simpler, easier, and I believe also safer. In uncomplicated cases it enables the surgeon to excise all of the sac, the whole of which is readily drawn up into the inguinal w^ound; and it ensures closure of the parietal peritoneum without leaving a pouch which will predispose to recurrence. In complicated cases it gi\'es much freer exposure of the parts, and renders the surgeon master of the situation: if there is strangulation, the constriction is much more readily found and easily divided; if there is an anomalous distribution of the obturator artery, it is easily discovered, and accidental hemor- rhage may be promptly- controlled.; if the gut is gangrenous, and intestinal resection or anastomosis is required, these may be done much more rapidly and safely than by the femoral method. By the latter route Gim))ernat's ligament, the usual point of constriction, cannot be divided under control of the eye; it may be impossible, owing to shortness of the mesentery, to draw down enough healthy bowel to perform a resection, and even when the anastomosis is accomplished, if one is required, it may be impossible to return the gut through the narrow femoral canal. The only alternative in such cases is to divide Poupart's ligament, a procedure which renders recurrence of the hernia almost certain, and in a form which it is extremely difficult to cure. Should there be a fecal abscess in the sac, however, it should be drained through a femoral incision before the inguinal operation is begun. The peritoneal cavity also should be well protected by gauze- packs before the gangrenous gut is reduced. If it proves impossible to draw^ the sac up into the inguinal canal, its neck should be opened and its contents should receive appropriate treatment. Under these circumstances the fundus of the sac may be allowed to remain in the femoral canal. Obturator Hernia. — This is very rare. Berger found it once among 10,000 cases of hernia. About 200 cases are on record. It is most fre- quent in elderly women. It is a hernia of slow" formation. The sac leaves the pelvis through the obturator foramen, and protrudes in the upper inner part of Scarpa's triangle, underneath the pectineus muscle, where the hernia can be more easily felt than seen. The thigh should be flexed, adducted, and rotated slightly outward: then the surgeon places his finger against the descending ranius of the pubis 800 HERNIA behind the addiietor h)iijiiis, and palj)utes carefully for tlie swelling (Maeready). The two limbs should be e()mj)ared. Sometimes l)oth sides are affected. The sac usually contains bowel, but the tube and ovary have been present in a few cases. The existence of a hernia seldom is recognized until strangulation occurs, and even then the true cause of the symptoms may be overlooked. Diagnosis. — The diagnosis in a case of strangulation, apart from the symptoms of intestinal ol)struction, would depend on the history of previous attacks of incarceration of the hernia, with relief of pain coincident with the sensation of something slipping back into the pelvis; the onset of the present symptoms with sudden pain in the region of the obturator foramen; on the radiation of pain in the dis- tribution of the obturator nerve; and on the discovery of a tender swelling beneath the pectineus muscle, by the mode of examination already indicated, together with palpation of the inner surface of the obturator foramen througli the ^'agina or rectum. Treatment. — Treatment consists in laparotomy and reduction of the hernia, with closure of the obturator canal by suture. The mortality has been about 85 per cent., largely because the condition has not been recognized in time. Fig. 804. — Left pudendal hernia, containing ovary, in a woman of eighty years. Diag nosis at operation (symptoms of strangulation). Recovery. Episcopal Hospital. Perineal, Pudendal, and Vaginal Herniae. — These are extremely rare. It is probable that congenital anomalies of the pelvic peritoneum (possibly preformed pouches) predispose to the development of these hernise. They occur about six times as often in women as in men. In the male the protrusion occurs in the perineum {perineal hernia), between rectum and prostate, or rarely in the ischio-rectal fossa. It may be associated with prolapse of the rectum. In the female the hernia may leave the pelvis behind or in front of the broad liga- ment. In the former case the protrusion may occur in the perineum, in the ischio-rectal fossa, or in the posterior vaginal wall (vaginal hernia). Vaginal hernia usually is associated with procidentia uteri. If ISCHIATIC Hh'RNIA SOI tlic iKTiiia loaxc's 11k' (h'1\ is in Iroiit ol" tlic hrdud lii^aiiiciit, as is more ohvu tlic case, it enters the hibiiiiii majus {yiidendal hernia, Fig. rej)arati\e process continues tlie infectious material is iocahzed in one or many regions, wliieli are shut off from tlic rest of tlie peri- toneal cavity l)y adliesions between the coils of intestine, the omentum, the parietal peritoneum, and neighboring structures, such as bladder, uterus, stomach, gall-bladder, diaj)hragm, etc. The result of such an attack of peritonitis is the formation of nniltiple residual abscesses. INIany surgeons confuse this condition, which is frequent, with that described by Mikulicz as progressive fibrino-i)urulent peritonitis. The pathogenesis of the latter form of ])eritonitis, which is rare, has })een described abo\e; T beliexce the idea tliat it is of fre(iuent occurrence rests on faults of observation. Purulent exudates collect, and residual abscesses form chiefly in the dependent portions of the peritoneal cavity, especially the pelvis, the iliac fossa, tJie lum})ar gutters, or in the subphrenic regions (Plate VII, fig. 5). If the resistive powers of the patient prove unequal to the task of localizing an attack of peritonitis after it has reached the diffuse stage, the infection continues to spread, until what may be called general peritonitis is present (Plate VII, fig. 4). From this patients seldom reco^'er. They die of toxemia or septicemia before the invading forces have been overcome. And if the virulence of the infecting organisms is very high, or if the patient's resistance is very much below par, the peritoneal infection may spread with alarming rapidity from the very first. In such cases little or no exudate is formed, but, on the con- trary, the bacterial poisons are c^uickly absorbed, and the patient dies with a dry peritoneum, without adhesions, without exudate, but with the intestines red, friable, and on the verge of disintegration. This usually is described as septic peritonitis, though the term of A. O. J. Kelly (1896), toxic peritonitis, is preferable. When there is a tendency for minute hemorrhages to occur, either in the subserous tissues, or free into the peritoneal cavity, rendering the scanty exudate blood-tinged, the condition is sometimes called hemorrhagic peritonitis. Clinical Course and Diagnosis. — The symptoms of oncoming peri- tonitis are so inextricably bound up with those of the condition to which it is secondary, such as appendicitis, or intestinal perforation, that it is difficult to distinguish between the two, especially as peri- tonitis is rightly regarded not as a distinct disease, but as itself a com- plication of the underlying disease. However, it is convenient to describe the clinical picture which a patient with peritonitis presents to the observer, and then to study more in detail the physical signs on which a diagnosis of peritonitis is based. Acute Local Peritonitis. — The initial more or less diffuse and colicky pain of the primary lesion (in the appendix. Fallopian tube, gall- bladder, etc.) is succeeded within a few hours by a pain which is burn- ing, intense, and local. This is increased by movement, by pressure, by coughing, or deep breathing. The affected area of the abdomen 806 ABDOMINAL SURGERY IN GENERAL becomes extremely tender, the muscles overlyinj? it are rigid, peri- stalsis is arrested in the immediate vicinity of the lesion, and there is local tympany due to paresis and distention of the bowel most affected by the peritonitis. These factors account for the persistent consti- pation, and the nausea and vomiting. There is moderate elevation of temperature, leukocytosis, and a raj)id, hard, wiry pulse. Acute Diffuse Peritonitis. — This usually is a sequal to the local form, but in cases of gastric or intestinal perforation may exist from the very first. All the symptoms are aggravated, and at the onset there often is marked shock. The pain is almost unendurable, con- stant, burning, or boring, and spreads w^idely over the abdomen.^ The abdomen is of board-like rigidity. throughout, and exquisitely tender. The patient's respiration is entirely thoracic, and the flat or even scaphoid abdomen moves not at all, even in deep inspiration. The patient lies on his back or side, with knees drawn up to relax the abdominal muscles. The constipation is absolute; no flatus is passed; peristalsis is entirely absent; vomiting is almost continuous, the patient regurgitating with little eft'ort, every few minutes, small amounts of offensive prune-colored liquid. The symptoms of this stage pass almost imperceptibly into those of general peritonitis. The evidences of systemic poisoning become pronounced : there is more fever, greater leukocytosis, rapid, shallow respiration; the eye is bright, the expres- sion anxious, and the skin from being rough and dry becomes covered with a clammy moisture. The pulse grows very rapid, running, weak, and almost uncountable. The abdomen begins to become distended, rigidity lessens and then disappears; extreme distention finally develops. In the last stages tenderness and leukocytosis may be absent. Death is preceded by delirium, great restlessness, cyanosis, air hunger, sweating, subsultus tendinum, carphologia, and finally exhaustion. In rare cases of very severe infection, from the first, and not infrequently before death, the abdomen is soft, and there is diarrhea ("septic diarrhea"). The history of the case is of great value in diagnosing the primary lesion, but in peritonitis, as in most other acute lesions, much more reliance can be placed on physical signs than on the clinical history or the symptoms. It is well, therefore, to consider in more detail some of the physical signs which were enumerated above. Rigidity of the Abdominal IFa//. — This is due to reflex (involuntary) muscular contraction, brought about by stimulation of the spinal segments, whence arise both the nerves supplying the diseased abdomi- nal viscera (sympathetic fibres) and those which supply the over- lying muscles of the abdominal wall. So long as the peritonitis is localized, the rigidity wdll remain local; spread of rigidity is an indica- tion that the peritonitis is spreading in a similar manner. In some 1 Peritonitis limited to the area occupied by the small intestine, and confined beneath the omentum, may run its course without any of the usual symptoms, so long as parietal peritoneum is nowhere affected; it is only the parietal peritoneum which has pain sense, according to Lennander, while that covering the viscera is insensitive. PERITUMTIS 807 cases the stimulus seems to alVect the sensory as well as the motor iierxc Hlaments of the ahdominal wall, and hyperesthesia ol" the skin oxerlyinj; the diseased \iseus is present. ( Onversely, inexpert j)alpa- tioii of the ahdominal wall with a eold hand, or with fin^'ers lacking in skill and jjentleness, will stimulate these sensory cutaneous filaments, and will cause contraction of the abdominal nmscles, and thus may make the careless examiner think that rij^idity flue to i)eritonitis is present, when he has himself caused this rigidity by his inexpert examination. The true reflex rigidity of the abdominal muscles can be recognized only by experience, and many physicians never learn to recognize it, owing to inditierence and lack of practice. It is the tadus cruditufi, the experienced touch, that counts, and the only way to gain this experience is to palpate with attention and care the abdomens of hundreds of patients with and without peritonitis. Palpation for muscular rigidity should be made with the finger ti])s, but with the utmost gentleness. Place the ti])s of all four fingers of both hands very lightly on the surface of the abdomen at some point far rernoved from the region suspected of disease and palpate the normal abdominal wall first. Do this gently and circumsi)ectly in every case, and you will gain your patient's confidence, and further palpation will be easier. Having placed the fingers barely in contact with the abdomen, arrange them so that alternate pressure wath each hand will be in a direction parallel to the course of the fibres of the muscle you are about to palpate. Then, without at any time raising your fingers from the surface of the abdomen, and with extreme gentleness, bear down for a fraction of a second first with one hand and then witli the other. Repeat this manipulation a number of times before passing to another region of the abdomen, and accom- plish this transfer of your hands without raising them from the abdomi- nal wall, so as to spare the patient the shock of a new contact. Having reached another region, repeat your manipulations here, and so on until the entire abdomen has been covered. This should include the rectus muscle of each side both above and below the umbilicus, and the oblique muscles not only in the iliac and hypogastric regions, but in the flanks and in the loins as well. In this way you will very quickly learn the difterent sensation conveyed to the palpating finger by a rigid or a normally relaxed muscle. Do not be in a hurry, and be more gentle than you think anyone else can be. This is not at all the same kind of palpation that is desirable when one is seeking to discover a mass wdthin the abdomen. It is this latter form of palpation that most physicians attempt when they seek for rigidity, with the result that they usually fail to recognize its presence. Here the hand is laid flat on the belly, and by gentle and rocking pressure alternately with the heel of the hand and the pulps of the fully extended fingers, the examiner seeks to depress the abdominal wall until the underlying structures can be palpated. If rigidity is present, it is a clear indication that some degree of peritonitis exists. Slight rigidity usually indicates a mild grade of 808 ABDOMIXAL SURGERY IX GENERAL peritonitis so long as the abdomen is not distended; and marked rigidity indicates peritonitis of much more serious import. So, too, the extent of the rigidity on the surface of the abdomen is a fair indi- cation of the area of peritoneum involved. But if the patient is excessively fat, or if the muscles are very much atrophied, no rigidity may be palpable. Tenderness on palpation is of almost equal importance with rigidity. Cutaneous hyperesthesia, which was referred to above, is described as superficial tenderness; what is to be studied now is known as deep tenderness. When this is exquisite it usually signifies pus under ten- sion, whether the pus is localized as an abscess or free in the belly as in diffuse peritonitis. Rigidity scarcely ever is present without tenderness, though the latter may not be elicited by very gentle palpation in the case of a very muscular or extremely rigid abdominal wall. But tenderness frequently persists after rigidity has given way, as in time it usually does, to abdominal distention. This per- sistence of tenderness is a very important sign, often indicating that gangrene has occurred in the organ diseased. Palpation through the rectum often is of great value, in discovering tenderness in the recto- vesical pouch. Percussion of the abdominal wall should succeed palpation. It should be done with the utmost gentleness, and not over any area which is very tender. It is possible by percussion, much more safely than by palpation, to determine the presence of an abscess, or of an inflammatory mass due to adherent omentum. These will give a dull note on percussion, and will be surrounded by areas of tympany. The existence of an effusion which is settling in the pelvis or the loins may also be ascertained by percussion. Finally, auscultation should not be neglected. In cases of diffuse peritonitis the abdomen is quiet; no peristaltic sounds are heard unless at a great distance from the focus of infection. Distention of the abdomen is a late sign of peritonitis, and of bad prognostic import. A diagnosis which is delayed until the abdomen is distended is of little use. The onset of distention occurs pari passu with the disappearance of abdominal rigidity. The distended abdomen may be tense from tympanites, but it never is rigid. The distention is the result of two factors: the first is paresis of the intes- tinal nerves and of those supplying the abdominal wall, as a result of poisoning by the absorption of toxins; this relaxes the muscular tunic of the intestines and makes the belly wall soft. The second factor causing distention is the occurrence of fermentative and putre- factive changes within th^ intestines, producing tympanites. The constipation which has already been noted, and the distention of the abdomen which is here discussed, are the consequence and not the cause of the patient's illness. He is not ill because his abdomen is distended, but his abdomen is distended because he is ill. Differential Diagnosis. — Peritonitis must be distinguished from the colic of acute gastro-enteritis, from pleurisy and pneumonia, and from PERITONITIS 809 intestinal obstrnction. Other conditions with which it is sometimes confounded will be discussed in connection with the several lesions which may cause peritonitis. Acute (lajitro-rntcritis.— In mild cases this is attended by sudden, sharp, stabbinjj pain, which varies in intensity from time to time — infcstinal colic. The pain is relieved by pressure on the abdomen. There is no tenderness, no rigidity, no change in pulse or tempera- ture, and no leukocytosis. Vomiting is unusual, but if it occurs it is not repeated when the stomach has been emptied. In severer cases there is vomiting, and general jjbdominal pain and tenderness. There may be fever, with increase in the pulse rate, but there is no rigidity of the belly wall; and there is diarrhea, which is rare in peritonitis. In cases where doubt remains after a thorough examination, visit the patient again after an interval of three or four hours, and keep him in constant surveillance until the nature of the disease is manifest. Pleurisy and pneumonia often are attended by pain referred to the abdomen, and in children this may be the only complaint. There is no nausea or vomiting; only slight rigidity of the upper abdomen, and only superficial tenderness (cutaneous hyperesthesia) are present. There is no deep tentlerness. If the chest were examined in all cases of acute abdominal disease, whether the presence of pulmonary complications be suspected or not, the surgeon would be saved many an error and the patient an unnecessary operation. Even if the pul- monary lesion is so deep-seated as to give no distinct physical signs, a diagnosis of peritonitis usually may be excluded by the absence of physical signs in the abdomen, and by the presence of symptoms, such as rapid respiration, dyspnea, slight cyanosis, etc., which are charac- teristic of thoracic disease. Intestinal Obstruction frequently is complicated by peritonitis in its later stages, just as peritonitis may be followed at any time by intestinal obstruction. A differential diagnosis often is impossible when either condition has existed for some days, because then both conditions may be present. But at the outset the two affections pre- sent very different symptoms and physical signs. In intestinal obstruction, attentive study of the patient's history usually will reveal a cause for the obstruction in some previous attack of peri- tonitis. The attack of intestinal obstruction begins with colick}^ pains, and these are more or less relieved by pressure on the abdomen. The pain is intermittent, and between the 'paroxysms the patient may feel quite comfortable and may appear very well. In peritonitis the patient is decidedly ill from the very commencement of the attack, and there are no remissions. In obstruction the intervals between the pains rapidly shorten, but the pain does not for a long time become constant; in peritonitis it is constant from the beginning. In obstruc- tion there is absolute constipation, as in peritonitis, and no flatus is passed by rectum; vomiting occurs early, is persistent, and soon becomes of the projectile type (p. 885), with rather long intervals between the attacks of vomiting. In peritonitis, on the contrary. 810 ABDOMINAL SURGERY IN GENERAL the patient vomits oftener, the \'()iiiitus is small in quantity each time; and the vomiting is not projectile hut regurgitant in type (p. 806). In obstruction, as in i)eritonitis, the contents of the upper bowel are vomited after the stomach has l)een emi)tied; but in obstruc- tion the rejected matters finally become fecal, wliich never is the case in peritonitis. In obstruction there is no rigidity of the abdominal wall, and distention occurs early — often within a few hours. Rigidity is the most \'aluable early sign of peritonitis, but distention seldom occurs until after the lapse of eleven or twelve hours. The disten- tion of obstruction may at first be localized to the area immediately above the obstruction. Auscultation in obstruction detects extremely active and disordered peristalsis; sometimes peristaltic waves can be clearly seen through the distended belly wall. In peritonitis the abdomen is silent. In obstruction the temperature is not elevated, while in peritonitis it almost always is abo^'e normal. Leukocytosis is rare in obstruction, unless strangulation has occurred; but in peri- tonitis it is the rule. In both affections a steady increase in the pulse rate occurs, and is a most valuable sign. Treatment. — This is not the place to discuss the prcAcntion of peri- tonitis; but that it may be prevented often by prompt operation will be pointed out time and again in the following pages. What concerns us here is how to treat the patient after peritonitis has devel- oped; and I here exclude from consideration pelvic peritonitis in connection with gynecological affections. 1. In the early stages, before the peritoneal inflammation has become diffuse, surgeons are in perfect accord in recommending immediate operation, to remove the source of infection, and thus })revent the development of diffuse peritonitis. This is a much surer and far safer course to pursue than to trust to the unaided powers of nature to isolate and overcome the infection. If the source of infection is the appendix, it can be entirely removed; if it is a perforation of the intestine, it can be sutured, and the further discharge of infectious material prevented; if there is a lesion which cannot be treated in either of these ways (as in acute pancreatitis) the surgeon can at least isolate the source of infection by gauze packs, providing drainage, and thus preventing further intra-abdominal contamination. The details of operation, which should be completed quickly, will be described in connection with the various lesions which cause peritonitis. 2, When the peritonitis is in the diffuse stage surgeons are divided into two camps. There are those who think, with Ochsner, that it is safer to undertake no operation in cases of spreading peritonitis, but to trust to such measures as are detailed below to aid nature in isolat- ing the infection, and to wait until a residual abscess has been formed before instituting drainage. Neither Ochsner nor anyone else, how- ever, ever claimed that the patient could be cured without any opera- tion; the only question is whether the operation shall be immediate or postponed. Then there are other surgeons who believe, so long as the evidences of toxemia are not very marked, and so Jong as the I'ElilTONITlS 811 degree of (ilxloiiiiiidl rifiidUji is (jreaier fluin Us (listenthnt, so loiij;-, in short, as it is cvidnit that th(> patient is still reacting to tin- inlVction, that throufihout this period it will l)e more to the patient's ultimate advantage to institute drainage as soon as possible, and at the same time to treat the foeus of infection by excision, suture, or tamponade, ])rovided this secondarN' part of the operation can be carried through without unduly prolonging the procedure or entailing too great shock. My own belief and my practice, founded on a not very limited experience with all forms of i)eritonitis, is that operation under these circumstances is not only justifiable l)ut imperative. Ochsner and others limit the time within which inun(>diatc ()i)eration is to be done to the first thirty-six hours from the beginning of the illness. Xo doubt this is a convenient rule of thumb, but one patient will reach at the end of twelve hours a stage of peritonitis which will not be reached by another for two or three days. So that I think it is safer to decide the question in favor of or against immediate oi)eration n()t on the mere lapse of time, but, as I have done above, on the jxiUcnfs physiccd condiiiou. Especially valuable, I believe, is the persistence of' rigid it}/ or the onset of distention. Statistics might be quoted to support the views of surgeons on both sides of this question; but the fallacy of trusting to such figures is obvious. Only those who open the abdomen in all these cases know the state of affairs inside; those who do no operation give statistics founded on impressions, not on visual inspection of the peritoneum, and they are quite as likely to reckon as non-operative survivals, patients whose peritonitis never became widespread, as the really serious cases. .3. When diffuse peritonitis has so far advanced that rigidity has disappeared, and marked distention is present, the patient being ^'ery toxic and perhaps delirious, and constantly regurgitating the upper intestinal contents, almost all surgeons are in agreement with Ochsner that operation is more apt to hasten death than to gi^'e the patient a chance of recovery. In these cases, howTver, a well defined course of treatment musi be pursued, and occasionally even a seemingly moribund patient wull improve, one or more abscesses will form, and if these are drained at a propitious time recovery may yet ensue. This treatment, about to be described, is known as the Ochsner treat- ment of peritonitis, because so warmly espoused by this surgeon ever since 1900. It should be adopted in every case of peritonitis so soon as the diagnosis is made, whether or not operation is to be undertaken. If operation is to be done, this treatment will be of short duration, but it will aid materially in securing a good result; and the sanie treatment always is continued after operation until the peritonitis subsides. The' most important features of this non-operative or preparatory treatment are: (1) abstinence from everything hy mouth (hence it sometimes is called "starvation treatment"); (2) instillation of fluids by the rectum; and (3) the head high position. The patient is placed in bed either in Fowler's position (1900), hing flat on the back, and with the head of the bed raised twelve 812 ABDOMINAL SURGERY IN GENERAL to fifteen inches from the floor; or else in the so-callerl exa,2;gerated Fowler position, that is, in a semi-sitting posture in the bed (Fig. 805). This aids the gravitation of fluids to the pelvis and keeps them away from the subphrenic region, whence absorption is so rapid, thus dimin- ishing toxemia; and it lessens the chances of ])ulmonary complications. The patient is very apt to slide down in the bed unless supported. A special chair-like bed frame is the best support, but in emergencies a sand-bag may be passed beneath the mattress below the buttocks, or the patient may sit in a sling formed by tying the ends of a sheet to the two u])per posts of the bed. Fig. !S05. — Exaggerated Fowler position. One week after suture of a duodenal per- foration . Note slight elevation of reservoir for enteroclysis solution. Episcopal Hospital. Nothing ivhatever is given by mouth, not food, not water, not ice; nothing is permitted. Anything taken into the stomach rouses peris- talsis, and this spreads infection more widely in the peritoneum. Moreover, it increases nausea and provokes vomiting. The only thing ever to be introduced into the stomach is a stomach tube, wiiich should be used every six hours or less often, to relieve the stomach of regurgitated intestinal contents. A patient who has once experienced the relief which lavage of the stomach affords under these circum- stances is only too anxious to have the procedure repeated as soon as he feels his stomach refilling. To replace the fluids lost by intraperitoneal effusion, the patient is given saline solution or tap water by the rectum, as already described in Chapter V. This does not excite peristalsis, is quickly absorbed, allays thirst, restores blood-pressure, dilutes circulating toxins, and after operation seems to promote drainage from the wound. No drugs are required as a rule. Stimulants, such as camphorated oil, atropin, digitalis, or strychnin, seldom are indicated and do not seem to have much effect. Mor])hin very rarely is required; the pain soon ceases if nothing is taken by mouth and if nausea is controlled by lavage. Unless there is pain, sleep is not much interfered with. But I do not believe that morphin does any harm, and there is no reason why it should not be administered if it promotes the patient's comfort. This treatment shoiild he continued mitil the yeritonitis subsides. This period seldom is longer than three days, but it may be a week. RESIDUAL PERITONEAL ABSCESSES 813 The more ahsoliito the treatiiieiit from tlie first, tlie sooner will its efl'eet become manilest. I nder tliis form of treatment many patients who wonld (He nnder any other form of treatment, or after operation, will survive the peritonitis, and as the abdomen gradually softens, the surgeon will find evidences of one or more collections of pus. Very rarely a j)atient will recover from what ai)i)ears to ha\'e been a diffuse septic peritonitis without elfusion; when the abdomen is ojx'ned later to remove the cause of the disease, few adhesions and no pus may be foimd. I have seen only two such cases. Other ])atients will die in spite of this treatment; but it is not too much to say that the Ochsner treatment is the only form of treatment which gives these bad cases of peritonitis even a fighting chance. After the peritonitis subsides the patient is still far from convalescent. As the abdomen becomes softer auscultation will detect commencing peristalsis, and it will be painless; flatus will be passed, and the bowels may mo^•e s|)ontaneously or by simple enema. At this time small amounts of liquid food may be allowed by mouth; but if this is attempted too soon it will cause vomiting, rouse active peristalsis, break up newly formed adhesions, rupture an abscess which is just localizing, and perhaps cause intestinal obstruction. The patient must be very carefully nursed, and progress must be sure rather than rapid. When the abdomen has become entirely soft in parts removed from the seat of disease, when the bowels are acting normally, and the patient is a])proaching convalescence, then it is time to drain the abscesses which have formed. If these are neglected, and intraperi- toneal rupture occurs, the patient seldom survives even immediate drainage. Residual Peritoneal Abscesses. — So long as an intraperitoneal abscess is present, the patient is in constant danger. No delay should be permitted in instituting drainage when once it is ascertained that the patient can withstand the intervention. The abscess should be incised and drained, if possible without opening the uninvolved peritoneal cavity; nothing else should be attempted. Do not make any search for the cause of the peritonitis, but be content to secure drainage. Make sure, however, that you find all the abscesses. Plate VII, fig. 5, shows the most frequent sites in which residual abscesses form. In most cases a secondary and more formal operation is indicated some weeks or months later, to complete the cure by removal of the diseased organ (appendix, gall-bladder), closure of a fecal fistula, etc. Pelvic abscess sometimes may be drained by puncture through the rectum, or through the vagina. Unless the anterior rectal wall bulges and fluctuation is unmistakable it is safer usually to make a supra- pubic incision. This always should be preferred when there is also an iliac abscess; and always after opening an iliac abscess the surgeon should make sure that a separate pelvic abscess is not overlooked. A Ivmbar abscess is drained by an incision in the flank or loin. Subphrenic abscess is of great importance, because, though less frequent, it is so often overlooked. It may occur either (1) to the right 814 ABDOMINAL SURGERY IN GENERAL or (2) to the left of the falciform ligament of the liver; or (3) behind the right coronary ligament; or (4) in the lesser peritoneal cavity. Abscesses on the extraperitoneal surfaces are rare, and usually are secondary to hepatic abscess, in connection with which they are dis- cussed (p. 9o()). Of the four sites of subphrenic abscess mentioned above, that most frequently the seat of suppuration is the space behind the right coronary ligament and extending around its free margin to the subhepatic space. Most abscesses in this situation are secondary to appendicitis; the abscess tends to point through the lower intercostal spaces, except when intraperitoneal or intrapleural rupture occurs. Most of the abscesses in association with the left lobe of the liver in front of the left coronary ligament are due to gastric or duodenal lesions; those in the lesser peritoneal cavity may follow gastric or pan- creatic lesions; while those far to the left are rare and generally sec- ondary to splenic affections or are the result of diffuse peritonitis. The diagnosis of subphrenic abscess is based: (1) On the history of the illness, indicating a possible cause for the formation of an abscess in the subphrenic region; perforated gastric or duodenal ulcers cause almost one-third of these cases, appendicitis over one-sixth, hepatic affections about one-sixth, and the remaining one-third are due to miscellaneous affections (Barnard, 1908). (2) On abdominal signs and symptoms of an abscess — dulness, tenderness, mass, possibly rigidity. (3) On thoracic signs and symptoms, especially slight pleural frictions or effusion, or upward displacement of the lung with increasefl dulness over the liver. (4) On general signs and symptoms of suppuration — fever, leukocytosis, chills and sweats, and especially progressive emaciation. The treatment of subphrenic abscess involves drainage by operation; nearly every patient not operated on dies. In most cases of right-sided abscess the operation is by thoracotomy', as in operations for abscess of the liver (p. 937). Rarely an abdominal incision is proper. The general mortality is about 37 per cent. Peritoneal Adhesions. — This condition, which has been referred to (p. 802), often is described as chronic peritonitis; it is rather the result of a former peritonitis. There is no inflammatory process. The adhesions which developed during the existence of active inflam- mation remain, and by their interference with peristalsis cause symp- toms of which pain and obstipation are the most constant. The drag of adherent structures on the parietal peritoneum, the mesenteries or the female genitalia may render life miserable, and the patient may become an invalid. Purgation is apt to rouse such acti\'e peristalsis as to increase pain, and sometimes causes intestinal obstruction; and the usual symptoms of coprostasis are an annoyance unless the bowels are opened normally. There are other cases in which peritoneal adhesions develop as the result of such an attenuated infection that the origin of the affection cannot be traced. Such are many cases of Lane's kink, of Jackson's membrane, and other forms of peritoneal disease which have been recognized only within recent }ears. These are discussed at p. 896. TUBERCULOSIS OF THE PERITONEUM M,') The surgeon is powerless to prevent the formation of adlic.^ions in cases of acute peritonitis, and, indeed, often hails them witii delij,dit as aids to tlie i)atient's immediate recovery; l)Ut he is careful wlien he opens tiie abdomen in other cases to avoid manipulations wiiich will encourage the formation of useless and disabling adhesions. He does not handle the parts not concerned in the operation; he with- draws from the abdomen as little of the intestine as possible, and prevents it from becoming dried while it is exposed; and he is careful to cover all denuded serous surfaces by inversion with sero-serous sutures or by stitching the omentum over the defect. Various attempts have been made to j)revent peritoneal adhesions by the use of oily substances, but without much success. In recent laboratory work, however, Saxton Pope (1914) has found that a 2 per cent, solution of sodium citrate in a 3 per cent, (hypertonic) sodium chloride solution possesses great power in preventing peritoneal adhesions. Treatment. — In the treatment of peritoneal adhesions, it is only by experience that a surgeon can learn when to let well-enough alone. If the adhesions are broken up the new adhesions that form may be still more disabling, in spite of patient suturing and omental grafting. Unless the adhesions produce symptoms it is better, as a rule, not to interfere with them. Of course, if intestinal obstruction occurs, this must be overcome. Pneumococcic Peritonitis. — This occurs oftenest in ciiildren, i)ar- ticularly girls under the age of six years. ]\Iost cases are secondary to a pneumococcic infection of the lungs; but the primary focus may be situated elsewhere, as in the middle ear or the female genitalia. The infection probably is more often enterogenous than hematogenous. The physical signs are those of acute diffuse peritonitis (p. 80(3), but the patient's general condition is not so much affected as when the peritonitis is due to the ordinary organisms, and the death rate is much lower. In most cases there is a good deal of effusion, and this usually becomes encysted within the course of a few days or a week. It should then be opened and drained. Tuberculosis of the Peritoneum. — The tubercle bacilli may reach the peritoneum tlirough the blood-stream, from the mesenteric lymph nodes, directly from the intestinal tract, or from the Fallopian tube. In almost all cases there are other tuberculous lesions elsewhere in the body. Tuberculosis of the lungs frequently preexists, and in a large proportion of adult patients this will develop later if not already present at the time the signs of peritoneal tuberculosis are noted. As a complication of Pott's disease of the spine, tuberculosis of the peritoneum is not very rare. As a part of a general miliary tuberculosis (blood infection), tuber- culosis of the peritoneum has no surgical interest. The cases of most surgical importance are those in which a removable focus of tuber- culosis. exists in the abdominal cavity. This is most often the Fallo- pian iuhe in women, and the vermiform appendix in men. In children tuberculosis of the mesenteric lymph nodes is more frequent. In many 816 ABDOMINAL SURGERY IN GENERAL cases a tuberculous ulcer of the small intestine is the point of peritoneal infection. Here, as in the appendix, the tubercle bacilli penetrate the thinned floor of the ulcer, and usually without a macroscopical perforation, escape into the peritoneal cavity, which becomes widely covered with miliary tubercles. These feel like minute shot or sand- like particles, projecting from the serous surfaces. They are yellowish- gray in color. The same course of events occurs when the infection arises in the Fallopian tube, whence it may escape through the abdomi- nal ostium, or by a minute perforation. It is not improbable (Baum- gartner) that the lesion is not really primary in the Fallopian tube, but that this has been infected from its peritoneal surface; but at all events, the tuberculous process is most active here for the time being, presumably because the bacilli have found a fertile soil for develop- ment. Tuberculosis of a hernial sac is not very rare. Usually it is secondary to some intra-abdominal focus. The changes in the peritoneum are those characteristic of other forms of peritonitis, only very much milder in degree. Usually there is a moderate amount of exudate formed. This may be clear, yellow- ish, greenish, turbid, or even purulent; not seldom it is bloody. When the disease has lasted for many months, adhesions form, and may be very extensive, causing kinks, and leading to intestinal obstruction. The omentum becomes thickened and forms lumpy masses which often can be felt through the abdominal wall. As the omentum and mesentery both may become retracted from thickening and tuberculous infiltration, these masses usually are situated in the left hypochon- drium. The intestines lie mostly below and to the right, and their tympanitic state adds to the distention of the abdomen. Among the adherent intestinal coils small collections of puruloid matter may occur. Rarely there is a large encysted collection of fluid. Caseous changes in the mesenteric lymph nodes are a late occurrence. The intestinal walls become very friable, and internal (entero-enteric) fistulse may form; occasionally an external fecal fistula develops spontaneously. In infants a tuberculous abscess may discharge through the umbili- cus, as in a case under my care some years ago at the Children's Hospital. Symptoms and Diagnosis. — The disease is one of early adult life, and of early childhood. Before five years of age it is not infrequent. It is rare after thirty-five or forty years. Most cases occur in women between eighteen and thirty years of age. Tuberculous peritonitis may begin rather acutely, or it may be chronic from the beginning. In the former case, after a few weeks of malaise and gastro-intestinal derangements (colics, attacks of con- stipation and diarrhea, nausea) the first thing to attract the patient's attention is enlargement of the abdomen, due to serous effusion. This may persist unchanged for months, but usually there are times when the abdomen seems to become smaller. As time goes on, adhe- sions begin to form, and if spontaneous recovery takes place (and it is not unknown) the abdomen becomes softer, the bowels act normally, TUBERCULOSIS OF TlIK I'EIUTONEUM 817 the gciRTal health improves, and tlie patient eonvalesees. Or an eneysted coUeetion of llnid may form, and be cured by evacuation. In cases which are chronic from the beginning the i)r()dromal symptoms may have existed for many montlis; there rarely is nnich ell'usion; often none can be detected. Omental masses may be palpabl(\ and they may change their site and their form from time to time, in the course of weeks or months, from no appreciable cause. Usually the subjective symptoms are slight, unless the adhesions cause intestinal obstruction, or secondary infection produces hectic fever. So long as the patients lie quiet in bed and are carefully nursed little change in their condition may be appreciable from month to month (Fig. SOO). Fig. sou. — Tuljerculosis of the peritoneum with effusion. Episcopal Hospital. The diagnosis of peritoneal tuberculosis will be strengthened by finding any tuberculous focus elsewhere in the body. Tuberculosis of the bones usually will be easily detected; but examination should also be made of the lungs, testicles, prostate, seminal vesicles, and kidneys, as incipient lesions in these structures often are overlooked. Treatment. — The general hygienic treatment already recommended (p. 82) for patients with tuberculosis is most important in cases of tuberculous peritonitis. A fair proportion of cases, as pointed out by Fenger (1901), tend toward spontaneous recovery. If improvement under general hygienic treatment is progressive, no operation is indi- cated. In other cases, however, effusion persists; the patient does not gain ground, and may grow progressively worse. In these patients, the propriety of operative interference must be considered. Operation has been found, empirically, to be of most value in cases with effusion. Tapping and aspiration of the fluid never have produced as good results as formal incision and evacuation. Probably this is for the same reasons that incision and evacuation of cold abscesses in con- nection with joint tuberculosis are more successful than is aspiration; the peritoneal effusion of tuberculosis is similar to a cold abscess elsewhere, and it is important to prevent the occurrence of secondary infection, either from the surface of the body or from within the intestinal tract. The abdomen should be opened in women, as if for an operation on the uterine appendages; in men, over the appendicular region; as these are the most frequent sites of primary foci. When- ever possible, without inflicting damage on the intestines, a tuber- 52 818 ABDOMINAL SURGERY IN GENERAL culous appendix in men should be removed; in women not only should one or both tubes l)e removed if affected, but a diseased appendix also. If adhesions are present the utmost caution should be used if any attempts to separate them are made. It is very easy to tear a hole in the intestine, and very difficult to repair it. Even if the intes- tinal sutures can be made to hold, union very seldom occurs, and a fecal fistula is the nearly inevitable result. Only if the bowel has been torn should the abdomen be drained. In other cases it should be closed tightly, to prevent any possibility of secondary infection from the surface of the body. In general it may be said that the immediate mortality following operation is very small, if proper precautions are taken against injuring the intestines. The ultimate prognosis is better when some focus such as the appendix or tube has been removed. Cure occurs much oftener in the ascitic than in the dry cases. If the patients are traced, nearly half the number will be found to die within a few years, and there will be many recurrences. But the prognosis is better with than with- out operation, and even a few years of comparative freedom from discomfort are not to be despised. OPERATIONS ON THE ABDOMEN. Laparotomy, or Abdominal Section, is a general term used to describe any operation which involves opening the peritoneal cavity.^ Definite operations are described more accurately by specific names, such as gastro-enterostomy, cholecystectomy, entero-anastomosis, etc. These terms will be defined in the proper place. They are sufficiently descriptive of the operation when they stand alone, and it is not necessary to complicate them by the prefix laparo- as is done by some surgeons; though all such operations include that of laparotomy. Abdominal Incisions. — In planning an incision through the abdomi- nal wall, the surgeon must have in mind not only ready and sufficient exposure of the abdominal viscera concerned in the operation, but also must endeavor to inflict as little injury as possible on the structures through which he cuts. There are three things to be considered in this connection — the bloodvessels, the muscles with their aponeuroses, and the motor nerves. The hlood-supply is so free that injury or ligation of any one of the main arterial trunks entails no danger of sloughing; but such injury should be avoided whenever possible because time is lost in checking the hemorrhage, and the wound is more liable to become infected if not kept dry. The deep epigastric artery is the most important; the superior epigastric is much smaller; and the deep circumflex iliac is not often encountered. ^ Laparotomy is derived from lairapa the Greek word for the soft parts between the ribs and pelvis. Celiotomy is used as an equivalent by some writers, but is considered less correct, as the Greek term KmAJa from which it is derived was used for a cavity of any kind — a joint, the heart, as well as the abdomen. OPE RATIONS ON THE ABDOMEN 819 Muscles should 1)0 split in the course of tlieir fil)ros whenever possible. Transverse section of muscle fibres is to be avoided; when this is unavoidable, the muscle must be repaired by suture. The resulting cicatrix in the muscle will resemble one of the lincfe transversae in the rectus abdominis muscle; this will not impair much the muscle's con- tractility, but it conii)licates the operation and is undesirable. The fibres of the tliree oblique muscles of the abdomen cross each other's course at various angles, and transverse division of one or two of these muscles can be avoided only in small incisions, such as the grifliron incision of INIcBurney (p. 820), where each muscular layer is split in the direction of its fibres. Incisions through the rectus muscle can be made of any length by splitting its fibres parallel to their course. An incision through muscular tissue is preferable to one through the linea alba or the linea semilunaris, because where several layers of tissue are traversed, as in cutting through a muscle and its sheath, much firmer union can be secured by suturing the wound in several layers, than where only one aponeurotic structure is available. The motor nerves are the most important of all structures to preserve, since they are so small that they cannot be sutured if cut, and the muscles supplied by them are paralyzed, and permit marked bulging of the abdominal wall in spite of accurate repair of muscular and aponeurotic structures by suture. These nerves are branches of the lower intercostals (6th to 12th) and they run more or less transversely forward from the intercostal spaces between the transversalis and internal oblique muscles, giving off branches to these and the external oblique; finally they perforate the posterior sheath of the rectus muscle and supply it by numerous fine twigs. Any incision which will divide these nerves is to be avoided whenever possible. An incision through the semilunar line will cut the nerves supplying that portion of the rectus muscle between the incision and the linea alba. Hence any longitudinal incision, unless quite short, should be made as near the linea alba as possible. If an incision is planned for any other part of the abdominal wall, it should, so far as possible, run parallel to and between two of the motor nerves. Section of nerves, as mentioned above, results in bulging of the abdominal wall from muscular paralysis (Fig. 807). This may entail great disability; and unlike incisional hernia (p. 772), with which it should not be confused, it cannot be cured by operation. All that can be done is to apply some form of abdominal support, as in cases of pendulous abdomen (p. 898). For operations on the stomach, intestines, and female generative organs surgeons usually employ a longitudinal incision splitting the fibres of the rectus muscle close to the linea alba on the right or left, whichever appears to give readiest access to the seat of disease. An epigastric incision of course is used in stomach operations (Fig. 808), and one in the hypogastrium for pelvic operations. For operations on the small intestines the incision usually is made to the left of the median line, just below the umbilicus; thus it may be extended upward 820 ABDOMINAL SURGERY IN GENERAL past the umbilicus without injuring the round ligament of the liver, which lies to the right. For opnations on the gall-bladder the usual incision is a longitudinal one through the outer third of the right rectus muscle, from the costal margin downward for four inches ; if more room is needed the incision is extended obliquely upward along the costal border to the ensiform process (Mayo Robson's ijicmon). Though this incision necessarily divides a number of motor nerves the resulting disability is much less than when an incision of similar length is used in the lower abdomen, where the tension is greater. Fig. 807. — Bulging of right side of abdomen from paralysis of motor nerves as result of long incision in right rectur muscle. Episcopal Hospital. Fig. SOS. — Incision for perforated duo- denal ulcer. Cicatrix three and a half inches. Suprapubic stab wound for drain- age. Episcopal Hospital. For operations on the appendix a lateral incision is employed. If only a small incision is required, the muscle-splitting or gridiron incision, introduced in 1893 by ]\IcBurney, is preferred by many operators.^ It is centred over McBurney's point, which is "from one and a half to two inches" from the right anterior superior iliac spine, and on a line from that point to the umbilicus. The skin incision is made parallel to Poupart's ligament, and the aponeurosis of the external oblique is divided in the same direction, parallel to its fibres. The fibres of the internal oblique are thus exposed. They run nearly at right angles with the previous incision, and are split in this direction. The fibres of the transversalis at this point run in the same direction as those of the internal oblique, and are split with them in the direc- tion of their course. The peritoneum is opened by an incision parallel to that through the skin. This gridiron incision cannot well be made more than tliree or four inches long. ]\Iany surgeons expose the appendix by a longitudinal incision splitting the outer * It had been used previoush- by L. L. McArthur. OPERATIONS ON THE MihOMEN .S21 fibres of the right rectus niusele; tliis has been calleti Dcaccru incision; he calls it the " simple incision." Or, after opening the anterior sheath of the rectus and displacing the fibres of this nniscle toward the median line (passing around the lateral border of the muscle without splitting its fibres), the posterior sheath of the rectus, together with the trans- versalis fascia and peritoneum, may be incised, as proposed by Battle in ISi)'), by Jalaguier and by Kammerer in 1' little except careful nursing is required in uncoinpHc-ated eases. If there is no vomiting, a drachm of hot water (not luke-warm) may he given every few minutes after eight to twelve hours. I am quite convinced that really hot water is less apt to cause nausea than is ice or ice-water. After eighteen to twenty-four hours small cpiantities of liquid diet may be given; soft diet may he l>egun on the third or fourth day. If the stomach has been the seat of operation mouth-feeding should not be begun for from twenty-four to thirty-sLx hours after operation. Vomiting is treated by total abstinence from mouth-feeding; by sitting the patient up in bed; by the administration of a glass of hot water; and finally by lavage. The treatment of peritonitis has already been considered (p. 810). The surgeon should not be in too great a hurry to have the patient's bowels moved. Unless they move spontaneously, an enema may be given on the third or fourth day. Owing to the pre-operative catharsis, and the abstinence from food after operation, it is futile to expect a free evacuation any sooner. Cathartics should not be given after operation unless the enema proves ineffectual. Calomel in divided doses, followed by a saline purge, usually is preferred. The patient may be turned on his side (this does not mean that he may turn himself) on the second day after operation if he desires it. He should be made comfortable. If there is peritonitis he w^ill be in the sitting posture (Fig. 805) and will not need to be turned over to ease his back. It is not well for the patient to leave bed until several days after the sutures have been removed. Rarely should an abdominal patient spend less than two weeks in bed. If the incision was large, or the operation very extensive, it may be advisable for the patient to remain in bed three weeks or longer. Only the very old should be hurried out of bed; and even they, if they can be made comfortable in a sitting position in bed, do just as well in bed as in a chair. Intestinal Localization. — Often during the course of an abdominal operation it becomes important to distinguish large from small bowel, or even to identify more or less accurately different areas of the latter as belonging to the upper jejunum, the middle of the small gut, or the lower ileum. In cases of peritonitis or intestinal obstruction, the small intestine may be so distended as to equal or exceed the size of the colon, so that mere size is no criterion. In many cases the longi- tudinal bands on the colon may be recognized, or even the sacculation of the large intestine; but inflammatory changes or distention may obscure such means of identification. The large intestine in fat adults is covered by epiploic appendages; but in children and emaciated 826 ABDOMINAL SURGERY IN GENERAL adults these are absent. The safest and most constant distinction is the attachment of the intestine to the posterior abdominal wall by its mesenteries (Da Costa, 1894). The small intestine is attached by its mesentery obliquely across the lumbar spine: the coils of small bowel rarely can be brought very far laterally in the abdominal cavity, _ but usually occupy its middle portion. The large intestine is attached to the posterior abdominal wall on the right and left of the abdomen, and transversely above. If all the intra-abdominal structures are pushed away from the right side by the use of gauze pads, the bowel which it will be impossible to push away, will be the cecum and ascend- ing colon. In inserting the hand, if the fingers be made to follow the peritoneum on the right across the flank, into the loin, and toward the median line, the first bowel they encounter attached to the pos- terior abdominal wall, will be the ascending colon. The same con- dition of affairs exists on the left side : the descending colon and the sigmoid have their posterior attachments further to the left than any of the intestines, and after all the movable bowels have been packed away from the left side, the immovable intestine, which remains relatively fixed, will be the descending colon or sigmoid. The sigmoid often has a long mesentery, and the sigmoid loop may prolapse into a right inguinal incision. The same is true of the transverse colon, which may be easily accessible from either iliac region or the hypo- chondrium. But the transverse co on is easily distinguished from other portions of the large bowel because it has the great omentum attached to it. The sigmoid and cecum are readily distinguished from each other by their mesenteric insertions. The mesentery of the small intestine, as already noted, crosses the lumbar spine obliquely, beginning above on the left, and ending at the cecal region on the right. The direction in which a coil of small bowel is running {i. e., which end is nearer the duodeno-jejunal junc- ture) can be ascertained by paying attention to the attachment of its mesentery. The coil of bowel to be investigated should be withdrawn from the abdomen, spread out, and untwisted, until the fingers can follow the mesentery down to its origin or root along the lumbar spine. If the bowel is not rotated on its mesentery, it is evident that it is running in the same direction as the root of the mesentery, and hence that its upper (duodenal) end is nearer the epigastrium than is its lower (cecal) end. The upper end of the jejunum is readily found by lifting the great omentum and with it the transverse colon out of the abdomen, and turning these structures upward on the patient's thorax. This makes the transverse mesocolon taut, and the jejunum is seen emerging from its lower layer just to the left of the spinal column. This is the duodeno-jejunal juncture. The duodenum here is retroperitoneal, and the first intraperitoneal coil of gut is the origin of the jejunum. This is an important landmark in gastro-jejunostomy. The lower end of the ileum, or the ileo-cecal juncture, is readily found, by running the fingers upward along the external iliac vessels as they lie at the brim of the true pelvis. The structure which arrests INTESTIXA L L()( 'A LIZA 'HON 827 X\w fiiif^tTs in till' lu'if^hhorliood of the ri^^lit sacro-iliac joint, will Ik- the tiTniination of tlir inesoiitery of the ileum where this passes into the (reuni. With a little praetiee it is not diffieult to scoop up into the wound, on the finger tips, the ileo-eecal loop, and thus to bring the Fig. 813. — -The mesenteric arteries in the upper portion of the jejunum. There are only primary vascular loops, and the vasa recta are long. appendix vermiformis into view\ Monks (1903) conducted studies in the hope of being able to diflferentiate at operation betw^een dif- ferent portions of the jejuno-ileum, without the necessity of tracing the entire small intestine dowmvard from its origin or upward from its termination. Chief reliance is placed on the arrangement of the Fig. 814. — The mesenteric arteries in the middle of the jejuno-ileum. Secondarj' loops are well-developed, and the vasa recta are shorter. viesenieric bloodvessels. High in the jejunum there are only primary vascular loops, with perhaps an occasional secondary loop, and the vasa recta are from 3 to 5 cm. long (Fig. 813). Midw^ay, sa}' at ten feet from either end, the secondary loops are a prominent feature of 828 ABDOMINAL SURGERY IN GENERAL the mesenteric vessels, and the vasa recta are shorter (Fig. 814). In the lower ileum the vessels are much less easily distinguished, owing to the deposition of fat in the mesentery; the loops, if visible, are much more complex, and the vasa recta are short and irregular (Fig. 815). The upper jejunum is larger in diameter, its walls are thicker, and often the valvulte conniventes are palpable, or they may be visible by transmitted light. The lower ileum is smaller, and its walls are thinner. Fig. 815. — In the lower ileum the mesenteric bloodvessels can hardly be distinguished, owing to the deposit of fat. The preparations shown in Figs. 81.3, 814, and 815 are from the laboratory of operative surgery in the University of Pennsylvania. Intestinal Sutures. — The underlying principle in suture of organs covered with peritoneum is to bring serous surfaces into contact. This principle appears to have been introduced by Jobert de Lamballe in 1824. It is analogous to the principle adopted in surgery of the vascular system (Chapter X), always to bring intima into contact with intima. Such apposition, both of the intima which lines blood- vessels and of the peritoneum which covers the abdominal viscera, results in much more rapid and certain union than where the muscular or fibrous layers of these structures are sutured without bringing their serous surfaces into contact. Any suture which brings serosa into contact with serosa may be called a sero-serous suture. There are many varieties of this suture in use at the present day, to which the names of various surgeons have been attached. As already mentioned, this principle was used by Jobert in 1824; but in 1826 its application was simplified by Lem- bert, and to this day an interrupted sero-serous suture is known as a Lembert suture (Fig. 816). If the suture did not hold well he included tissues down to the mucous coat of the bowel, and Halsted, in 1887, renewed this injunction. It is said that it is easy to tell by the sensa- ' tion imparted to the surgeon's hand, when the needle has caught up the tough submucous tissue. As a matter of fact the needle often, if not indeed usually, penetrates all the coats of the intestine; and this makes no difference so long as no fecal leakage occurs along the needle IN TES TINA L iSVT UREA'S .S29 track. This is prcxciiti'd hy tlic use of (1) rouiid-poiiitcd lurdk's, and (2) linen celluloid thread (I'agenstecher's suture, !!)()()), wliich ])()ssesses no capillarity. This suture material becomes encapsulated and remains })ernianently. For additional security in intestinal wounds, and especially to check bleeding; from the cut niaruins of the bowel, it is the rule to enij)Ioy also a through-and-through suture, which passes through all the coats of the intestine. This is inserted before the sero-serous suture, is Fig. 816. — Perforation of the bowel, Ijeinfj; clos(!d hy three Lembert sutures. Fig. 817. — a, Czeruy-Lemljert suture; b, Albert-Lembert suture. (See the text.) knotted within the lumen of the bowel, and should be of absorbable material so that it will ulcerate out into the intestinal canal when union is firm. Chromic catgut (No. or No. 1) is the best material. The principle of the through-and-through suture knotted within the lumen of the bowel we owe to Albert. A diagram of the Albert- Lembert suture is shown in Fig. 817, b. Czerny's suture did not penetrate the mucosa, and was not knotted within the bowel (Fig. 817, a). Fig. 818. — Gely's suture. Fig, 819. — a, The first points of a Gely suture, used to close a puncture, b, a purse-string suture, used to close a per- foration. Suture of Punctures and Perforations. — A mere puncture may be inverted by a couple of Lembert sutures (Fig. 816) or by the first points of a Gely suture (1844) (Fig. 818). A perforation usually may be closed by a purse-string suture (Fig. 819, 6), but if it is large it must be sutured as a wound in a direction either transverse or parallel 830 ABDOMIXAL SURGERY IN GENERAL to the long axis of the intestine, whichever puckers the bowel less. As there seldom is bleeding from the edges of a perforation it is not usually necessary to use a through-and-through suture, the sero-serous suture being sufficient. Suture of Incisions or Wounds. — Gunshot wounds resemble perfora- tions and require the same treatment. Ruptures, lacerated and incised wounds, especially operation wounds, usually require first a through-and-tlirough suture to check hemorrhage. This may be Fig. 820. — Closure of an intestinal wound by a continuous through-and- through suture. The knots lie within the lumen of the gut. Fig. 821. — Continuous sero-serous suture (Dupuytren's suture). either interrupted or continuous. The needle is entered at one end of the incision, from the mucous surface, emerges on the peritoneal surface, crosses to the opposite side of the incision, and there again penetrates all the coats of the bowel from the serous to the mucous surface. It is then knotted; the knot thus lies within the lumen of the bowel. If an interrupted suture is desired, both ends of the thread are cut short, and other sutures introduced about one-half a centi- meter apart until the wound is closed. If a continuous suture is pre- ferred, only the free end of the thread is cut short, and the needle is Fig. 822. — Right-angled sero-serous suture of Cushing. re-introduced on one side of the wound from its mucous surface, and traversing all the coats of the bowel, emerges on the peritoneal sur- face. The needle is then carried across the wound to its opposite lip; here enters the serous surface of the bowel, traverses all its coats, and emerges on the mucous surface. This completes the second stitch, and the thread is then drawn taut, carefully inverting the lips of the wound as this is done. Each similar stitch is pulled taut until the other end of the wound is reached, when the suture is knotted and the INTESTINAL RESECTION 831 knot is allowed to retract within the lumen of the bowel (Fig. 820). To reinforce this throuiih-and-tiirouKh suture, a coniinuous scro-scrous suture (known also as i)upuytren's suture) is applied (Fig. S21). Any point which seems weak may be reinforced again by an interrupted suture. When there is much tension on the parts a sero-serous suture, inserted as shown in Fig. S22, usually holds better; it is known as the righi-auyird srro-scwus suture (also by the name of Ilayward W. Gushing, 1889). Or a mattress suture, either interrupted (Fig. S23) or continuous (Fig. S24) may be employed; this is known })y Ilalsted's name (1887). Fig. 823. — Interrupted mattress suture. (Deaver and Ashhurst.) Fig. 824. — Continuous mattress suture- (Deaver and Ashhurst.) Intestinal Resection.— When it is necessary to resect a portion of the intestinal canal, the mesentery is first tied off. This is done by a series of interlocking ligatures applied about an inch from the intes- tinal attachment of the mesentery, and never over quite as wide an area as the length of gut to be removed, for fear of endangering its vitality. The gut above and below the diseased area is then double clamped: suitable clamps, with their blades covered by rubber tubing, introduced into surgery by Rydygier (1881), and popularized by Doyen (1900), may be applied to healthy bowel, and if clamped only tight enough to appose the mucous surfaces may remain in place for an hour or more without inflicting any injury. These clamps should have light, elastic blades, which meet at their tips before the bodies of the blades come together (Fig. 825). They prevent fecal extrava- sation and also serve the purpose of temporary hemostasis, like the elastic band of Esmarch used in amputating. In emergency pieces of tape may be tied around the bowel. Such clamps should be applied to the healthy bowel an inch or more above and below the proposed limits of resection. Any ordinary clamp forceps are then applied at the limits of the diseased area, w^hich is thus cut at each end between two pairs of clamps (Fig. 826), so that no fecal extravasation occurs. The subsequent procedure depends upon whether it is desired to restore the continuity of the intestinal canal by anastomosis, or to establish [a false anus in the wound. The best way to establish a false anus after intestinal resection is to suture the two coils of bowel together like a double-barrelled shotgun—" en canon de jusil," as the 832 ABDOMINAL SURGERY IX GEXERAL French call it. This is easily accomplished by a few sero-serous sutures. Then the circumference of each intestinal coil is sutured to the parietal peritoneum, leaving about an inch of each gut pro- truding from the wound. The clamps used for resection may be left Fig. 82.5. -Clamps used in gastric and intestinal surgery. Note the form of the blades; in the upper (three-bladed) forceps the rubber tubing is in place. on the protruding ends for a few days (or until the peritoneal cavity is shut off by adhesions), if there is no urgent need to secure a fecal evacuation; or the ends may be simply ligated and be left to open themselves when the slough separates. Other methods of forming a Fig. 826. — Intestinal resection. After the mesentery has been ligated and cut close to the bowel, the resection clamps are appUed, and the diseased bowel is cut away. false anus are discussed at p. 914; and the treatment of this condition is considered at p. 894. Intestinal Anastomosis. — This may be accomplished by uniting the gut end-to-end (circular enterorrhaphyj ; or, after closing the open ends INTESriNA L ANASTOMOSIS 833 of tlic intestines, tliese may he plaeed side by .side and a lateral anas- tomosis may be establislicd (X. Senn, 1889). By an implantation is understood an operation in which the end of one bowel is sutured into the side of another, mnoli as the ileum is implanted into the cecum. End-to-end Anastomosis.— The rubber-covered clamps employed durinsj; he intestinal resection are left in place. By bringing? them parallel to each other, the ends of the gut are approximated; these then look at the surgeon like a double-})arrelled shot-gun. This brings four layers of intestinal wall to view, two of which are apposed. Fig. 827. — Encl-to-ond aimstoinosis. The through-and-through suture has been started. Fig. 828. — End-to-end anastomo- sis. Passing the through-and-through suture at the mesenteric attachment. 1. First, a continuous through-and-through suture of cliromic catgut is applied: this is begun by introducing the needle from the mucous surface of that coil of gut on the operator's right, at the anti- mesenteric point. The needle is pushed through the apposed intes- tinal walls from the lumen of one gut into that of the other, where it emerges on the mucous surface, having in its course traversed all intervening layers of both guts: of the first coil from the mucous to the serous, and of the second coil from the serous to the mucous surface. The first stitch is then tied, the knot coming within the lumen of the bowel. The end is left long. The suturing is then continued (Fig. 827) toward the mesenteric attachment, and when this is reached the suture is passed as indicated in Fig. 828. The suture is continued around the margin of the gut, always passing from the mucous to the serous surface of the first coil and from the serous to the mucous siu-face of the second coil of bow^l. When the point of beginning is reached at last, the suture is terminated by knotting it to the original end, which was left long for this purpose. When both ends are cut short, the knot disappears into the lumen of the bowel. 2. The clamps may then be removed, and the operation is com- pleted by passing a continuous sero-serous suture around the entire anastomosis, thus reinforcing the through-and-through suture. 3. The mesentery will become redundant when the intestinal ends are approximated; its free border may be stitched to the anastomosis. 53 834 ABDOMINAL SURGERY IN GENERAL ]\Iaunsell (1892) thought it facihtated the operation of circular enterorrhaphy to evaginate the divided ends through a longitudinal incision in one of the coils of intestine. After suture of the divided ends has been thus completed, from their mucous surface, they are replaced, and the intestinal incision through which they were withdrawn is closed. A partial intussusception of the sutured ends remains (Fig. 829). M. E. Connell (1892) advocated only interrupted mattress sutures, penetrating all the coats of the bowel, and tied on their mucous surface. Fig. 829. — Maunsell's method of circular enterorrhaphy. a, the incision in one coil of intestine; b, the open ends of both coils evaginated through this incision, to facilitate suturing; c, the operation completed. t/ Lateral Anastomosis. — The open ends of the resected bowel must first be closed. If the limien of the gut is small, it is sufficient to apply a ligature in the groove made by a crushing clamp, as in the operation of appendicectomy (p. 856) and to invert this ligature by a purse- string sero-serous suture. When the guts are to be left in or near the wound after the lateral anastomosis has been completed (as in some cases of resection for strangulated hernia), it is sufficient to apply a strong ligature, as above described, without a secondary inverting purse-string suture. Thus time is saved. In most instances, however, and especially where the lumen of the resected gut is of large size, it is safer to close the end of the bowel by two layers of sutures, the first being a continuous tlirough-and-through suture of chromic catgut, and the second a linen sero-serous suture. Lateral anastomosis should be made in an iso-peristaltic direction (Fig. 830); though where afferent and efferent loops are sutured together en canon de fusil, and an anastomosis is subsequently estab- lished, the antiperistaltic direction of the anastomosis appears to make little difference (Fig. 831). IN TKSTINA L A NA STOMOSIS ^^r^ The formation of n lateral anastomosis is nnicli facilitated bv the use ot rnl.hcr-covcro.l intestinal clamps. The three-bluded "Roosevelt elamp, or one ol snnilar pattern, is very convenient (Fig. 825) The ) _j Fig. !S30. — Lateral anastomosis with intestinal coils in iso-peristaltic relation. Fig. 831. — Lateral anastomosis with intestinal coils in anti-peris- taltic r(>hiti()n. 830 ABDOMINAL SURGERY IN GENERAL clanij) should be applied so as to embrace a considerably greater area of bowel than that concerned in the anastomosis. The anastomosis is made on the free (antimesenteric) border of the intestinal loops. 1. The first step consists in the insertion of a continuous linen sero- serous suture close to the median blade of the clamp, for a distance a little longer than the size of the proposed intestinal opening, say about 8 to 10 cm. This suture is begun at one end of the proposed intestinal opening, where it is knotted, the free end being left long; it is continued in a straight line to the other end of the proposed anas- tomosis, uniting the two coils of intestine, as indicated in Fig. S.32. When this point is reached the suture is not cut, but the needle, still threaded, is laid aside temporarily, to be used again before the close of the operation. This needle and thread will be referred to as the sero-serous suture. 2. The surgeon then makes a longitudinal incision in one of the coils of bowel, about one centimeter distant from and parallel to the sero-serous suture already applied, and about 6 to 8 cm. in length. This incision divides first the serous and muscular coats of the gut; as these retract the mucosa pouts into the incision. The mucosa is cautiously opened at one point, so as not to wound the opposite wall of the bowel. Any discharge from the lumen of the bowel is wiped carefully away. Then the opening in the mucosa is enlarged by scissors to the full extent of the intestinal incision. If the mucosa seems redundant, as is often the case in the small intestine, it should be excised. The other coil of gut is then opened in a similar way for an equal distance. There are now exposed in the wound two apposed loops of intestine, each with a longitudinal incision in its antimes- enteric border. Each of these incisions has two lips, an anterior and a posterior. The two posterior lips are fairly close together, while the anterior lips are some distance apart. For purposes of descrip- tion it is convenient to apply definite names to these structures: we may speak of the coil of bow^el on the operator's right as the first gut, and that on his left as the second gut (frequently it is impossible to know which of these is the afferent and which is the efferent loop); each of these guts has an incision with an anterior and a posterior lip; the posterior lips are closely apposed to each other. Where the anterior and posterior lip of each incision join, is found the angle of the incision; one angle is at the end of the intestinal incision away from the operator {the far angle of the incision) and the other is at the near end of the incision (the near angle of the incision) . 3. A through-and-through continuous suture of chromic catgut is now to be inserted. The needle is entered at the near angle of the incision in the first gut, from its mucous surface, and traverses all its coats, emerging on its serous surface; it s then inserted at the near angle of the second gut, passing from its serous to its mucous surface. This stitch is then tied, the knot coming within the lumen of the bowel. The end of the suture is left long; it should not be confused with the end of the sero-serous suture (linen), which also was left long. The INTESTINA L A NASTO.VOSIS 837 throuf^h-and-throufili chrDinic f-atj^ut suture is continued away from the operator, uniting tiie posterior lips of the intestinal ineisions, as shown in Fig. So3, until the far angk-s of the incisions are reached. During this time the needle ;s passed always from tlie nuieous surface of the first gut through all its coats to its serous surface, and imme- diately into the serous surface of the second gut, emerging on the mucous surface of the second gut. Then the thread is drawn taut; the needle is carried hack to the side from which it started, and again enters the mucous surface of the first gut, traverses all its coats to emerge on its serous surface, and at once enters the serous surface of the second gut, and, traversing all its coats, emerges on its mucous surface in the lumen of the second gut. This is accomplished each time by one push of the needle, which is enabled to pass through the walls of both guts "all at one bite," be- cause the posterior lips of the intes- tinal incisions are so closely approxi- mated. When, however, the far angles of the intestinal openings are reached, it is no longer possible for the needle to pass through the walls of both guts all at one bite, but it is necessary for it to be passed tlirough each separately. But the same method of suturing may be continued: thus the needle always enters the first gut from its mucous surface and emerges on its serous surface; it then is carried across to the free margin of the second gut (at its far angle or on its an- terior lip), and always enters its wall from the serous surface and emerges on its mucous surface. This is readily understood by refer- ence to Fig. 833. This method of suturing is continued along the anterior lips of the intestinal incisions toward the operator until the near angles of the incisions are reached, when a complete cir- cumference will have been traversed by the through-and-through cliromic catgut suture, which is finally knotted to its original end, which was left long for this purpose at the starting-point, the near angles of the intestinal incisions. As this suture is being inserted in the anterior lips these should be carefully inverted so as to ensure accurate contact of their serous surfaces. If there is difficulty in securing proper inversion of the anterior lips, it is a very good plan to use for this part of the operation a continuous right-angled suture Fig. 833. — Lateral anastomosis: the through-and-through suture has united the posterior lips of the intestinal inci- sions, and the far end of these incisions has been reached. 838 ABDOMINAL SURGERY IN GENERAL similar to the sero-serous suture of Gushing (Fig. 822), except that here the right-angled suture should penetrate all the coats of the intestine, leaving the loop of the suture always on the mucous surface of the bowel (Fig. 834). This is known as C. II. Mayo's suture (1905). It is nothing else than a right-angled through-and-through suture. 4. When the application of the through-and-through suture has been completed, the rubber clamps may be released, but should not be removed from their position, as they serve to keep the parts accessible for the application of the final suture. This is a continuation of the sero-serous suture first applied, the needle of which, still threaded, was laid aside temporarily be- fore the application of the through-and-through suture was commenced. This sero- serous suture is now continued over the inverted anterior lips of the intestinal anastomosis, further inverting them and burying from sight the through- and-through suture. The sero- serous suture is finally arrested at the near angle of the anas- tomosis, where it is knotted to its own original free end, which was left long for this purpose. The clamps are then entirely removed ; the anastomosis is in- spected on all sides, any weak spot being reinforced by one or two additional interrupted sero- serous sutures. The intestines are then replaced within the abdomen. The advantages of lateral over end-to-end anastomosis are the following: the opening may be made of any desired size; there is no mesenteric attachment to be included in the sutures, and no fear of leakage at this weak point. The chief disadvantage is the additional time required for its performance, when it is employed after intestinal resection, because then it involves also closure of two ends of bowel. After lateral anastomosis following intestinal resection the coils of bow^l involved tend to straighten out, so that after some years little or no trace of the anastomosis can be found, even when it was made in an antiperistaltic direction. Lateral anastomosis I believe should be preferred (1) whenever the large bowel is concerned, as this has a relatively large extraperitoneal surface and, therefore, usually is not well adapted for an end-to-end anastomosis; (2) in cases where the Fig. 834. — Lateral anastomosis: the far angles of the Intestinal incisions have been sutured, and the anterior lips of the incisions are now being united by the through-and- through suture which is passed in a manner similar to the sero-serous suture shown in Fig. 822. INTESTINA L A NASTO.\f()SIS S39 two coils of s,tion. Ke.section with end-to-end ana.stomosis may be required n many instances it probably will be safer to close both ends of the duodenum, and do gastro-jcjunostomv or duodeno- jejunostomy (Deaver and Ashhurst). • r!lf ^?-V''',""'^? ''^}^'' ^'''' "f*^" ^>'^^fi profu.seIy. There usually IS httle difficulty m checking bleeding by suture or tampon, and if hemorrhage is arrested in good time, the immediate prognosis is reasonably good; though secondary complications, such as hepatic or subpiirenic abscess, empyema, or pneumonia, are much to be feared. Ihe general mortality after operation is from 35 to 40 per cent.; in a series of 37 cases uncomplicated bv injuries of other viscera, the mortality was only 16 per cent. (Patel and Loaec, 1912) (runshot wovmds of the .spleen, as in the case of subcutaneous injuries, frequently cause so much disorganization as to require splenectomy. ' Gunshot wounds of the pancreas almost alwa^•s are complicated by injuries of surrounding viscera. The best exposure is gained through the gastro-colic omentum. Tamponade is more successful than attempts at suture. Drainage always should be emploved If the injury is undiscovered, death is practicallv certain. ThV death rate after operation is about 43 per cent. (Diehl, 1911) CHAPTER XXIII. SURGERY OF THE GASTRO-IXTESTIXAL TRACT. SURGERY OF THE APPENDIX VERMIFORMIS. Appendicitis. — Inflammation of the vermiform appendix of the cecum is the most frequent form of abdominal disease seen by the surgeon. Its s\Tnptoms were described even by authors of classic times; but no one, except perhaps Melier, in 1S27, considered disease of the vermiform process as the chief, if not the sole cause of these symptoms until it was proved, about thirty years ago, by IMatter- stock in Germany that almost aU abscesses in the right iliac fossa were associated with a perforated appendix; and by Fitz in America that in cases of so-called typhlitis (inflammation of the cecum) and in cases of appendicitis the symptoms were identical. The term appendicitis was introduced by Fitz in 1886. Pathogenesis. — The anatomy of the appendix predisposes it to inflammation. It is filled with fecal matter charged with bacteria; it contains a long mucous canal which opens by a narrow orifice into the cecum; usually it is more or less kinked or twisted, owing to the shape of its mesentery; and the slightest swelling of its walls at any point may cause complete obliteration of its lumen, converting its distal segment into a closed cavity whose naturally infectious con- tents are thus markedly increased in virulence. In addition to these factors, the appendix possesses a precarious blood-supply : it possesses no collateral circulation; its arteries are "end-arteries;" and the slightest swelling or constriction or kinking of the organ may cut oft' the blood-supply completely, resulting in partial or total necrosis. The infection, in the vast majority of cases, is enterogenous; but hematogenous infection sometimes occurs (p. 850). In enterogenous infection the bacteria swarming in the fecal contents of the appendix produce a sub-epithelial reaction, which is known as the primary focus (Frimarinfekt) of Aschoff (1908). This occiu-s in the depths of one of the mucous crypts of the appendix, and consists of a collection of neutrophile leukoc\"tes. The epithelium itself, which overlies the primary focus, may be destroyed very early in the process, its place being taken by a plug of fibrin. Usually a number of these primary foci develop simultaneously. The inflammatory reaction spreads very quickly toward the serous coat of the appendix, and peritonitis may develop before the mucous surface is seriously diseased. In almost every case, the primary infection is due to the streptococcus; but invariably the colon bacillus invades the walls of the organ secondarily, APPENDICITIS 849 and soon ovor-fjrows the strrptoromis, so that cultures of the latter are lost. If resolution does not occur at this \-ery early staf^e of ajjjjendicitis, these intranuiral foci become confluent, and the condition is known as simple phlegmonous appendicitis. The existence of a primary catarrhal appendicitis, with ulceration as its result, is denied by Aschoff; what was formerly described as catarrhal apjx'ndicitis is now recognized as phle<:;monous (intramural) in nature. This phlegmonous stage is present, with few exceptions, whenever the disease has lasted more than twelve hours. Even should resolution occur at this early stage of the disease, the appendix will not return to its normal state; cicatricial tissue remains, .strictures may form, and the organ is more than ever predisposed to infection. If resolutions does not occur early in the phlegmonous stage of the disease, intramural abscesses develop, miliary in size. These are prone to perforate the serous coat of the a])pen(lix {miliary perforalions), causing jicritonitis without macro- scopic perforation of the appendix. Or they may rupture into the lumen of the appendix, producing ulcers. Ulcerative appendicitis never is the primary stage; it follows the phlegmonous, whether or not this has progressed to the stage of suppuration. In this ulcerative stage the mucous membrane frequently is honorrhagic; but the most serious complications of this stage are (1) ulcerative perforation (macro- scopic), which usually occurs on the anti-mesenteric border of the appendix; and (2) necrosis of the wall of the appendix. This necrosis may be the result of anemia from vascular thrombosis, or it may be due to the direct toxic influence of bacteria on the appendicular wall. In either case secondary invasion of the necrotic area by putrefactive microbes (from the fecal contents of the appendix) leads to gangrene. Separation of the slough formed in this manner produces yet another variety of perforation. Every attack of appendicitis passes through all the stages described unless arrested spontaneously or unless the appendix is removed. If resolution occurs early in the phlegmonous stage of the disease, and if the appendix suffers a number of such mild attacks (which may be so mild as to pass unnoticed), a condition described as chronic appendicitis may develop.^ This term implies not so much a chronic inflammation, as defined at p. 35, as it does the result of previous inflammatory attacks. The lesions are fibrotic and sclerotic in nature, and are most marked in the distal portion of the appendix, especially behind a stricture. In some cases repeated mild attacks lead to obliteration of the lumen of the organ, through the process of adhesion between its apposed granulating walls. This appendicitis obliterans (Senn, 1894) usually affects only the tip of the organ, but as the patient ages the entire lumen may be obliterated. 1 This is the teaching of Aschoff, whose studies of the pathology of appendicitis are the most recent and accurate. Other authorities have held that an acute attack seldom occurs except in an appendix already the seat of chronic appendicitis. Both views are harmonized if we admit that chronic appendicitis alway.s begins with a definite attack which is acute pathologically, no matter how mild chnically. 54 850 SURGERY OF THE G ASTRO-INTESTINAL TRACT Strictures, or actual occlusion of the lumen of the appendix may occur at \arious points. If a stricture only is present, it is usual for a coprolith or fecal concretion to develop behind it (Fig. 837), or between two strictures. If complete occlusion exists the tip of the appendix beyond the occlusion or the segment lying between two occluded points may become the seat of an empyema, during an acute attack; or if the infection dies out a cyst may succeed the empyema. Not infrequently in an acute attack temporary occlusion (from edema or kinking) occurs close to the cecum and the whole appendix is con- verted into an abscess, sac. Fecal concretions found in the a})pendix at operation almost surely are the result of a previous attack of appendicitis; after they are once formed they predispose, by their mechanical action, to further attacks and especially to perforation, which occurs oftenest behind the concretion. Foreign bodies which are rare in the appendix, act in much the same way as do the fecal concretions: they may lie in the lumen of the appendix for years without producing any symptoms. Fig. 837. — Gangrenous appendix with fecal concretion near tip. Note thickness of wall«. indicating previous attacks; stricture on proximal side of concretion; and imi)f'ndin{i perforation near tip. Episcopal Hospital. Causes. — Appendicitis is commonest between the ages of ten and thirty years, when all infectious disorders are most prevalent. Strep- tococci, especially diplococci, are the bacteria most often directly responsible for an attack of the disease; but why it is that they produce the attack at any given time is a mystery. The great frequency of enterogenous infection has already been noted; and it is probable that stagnation of the contents of the appendix from kinking is the main predisposing cause. Digestive derangements increase the virulence of bacteria in the intestinal canal, or are the result of this increased virulence ; and disordered peristalsis may force fecal matter containing these highly virulent organisms into the appendix. There is no good proof that appendicitis arises as the extension into the appendix of a catarrhal inflammatory process in the cecum. It is probable that intes- tinal parasites found in the appendix (Fig. 838) have no etiological significance. In some cases it is possible that infection occurs through the blood- stream (hematogenous). In this connection attention has been called (by Kellynack, Kretz, and others) to the histological resemblance of the appendix to the faucial tonsils, both of them containing much lymphoid tissue; and it has been held that appendicitis is an abdominal angina. But neither the clinical history of the patients, nor the AI'I'KSDICITIS 851 liist()l<),<;ic;il cximiinatioii of X\\v disoast'd a])i)(MHlicrs supports the theory of heinatoj^euous infeclion, except in extremely rare instances. One attack of appendicitis predisposes to another. Nearly 85 per cent, of oOOO |)aticnts under Deavcr's care bad bad a previous attack. Fig. 838.— Acute ai)|)("iulicitis, appendix containiii}; oxyuiis vcnniculaiis. (Xaturu size.) Episcoi>al Hospital. Acute Appendicitis. — Symptoms and Clinical Course. — Pain, nausea, and vojuiiing followed by tenderness and rigidity: These are the cardinal symi)toms of acute appendicitis. Usually without pre- vious warning- the patient develops a sudden colicky pain, more or less diffused throughout the abdomen or localized to the umbilical region. This pain is due to the disordered peristaltic action of the appendix in attempts to empty itself against resistance. It is analogous to the pain of biliary, intestinal, or renal colic; like them it excites nausea and vomiting. The ^•omiting is reflex, and suffices only to empty the stomach. It is not repeated unless peritonitis develops, when it assumes the type already described at p. 806. This primary nausea and vomiting follows and does not precede the initial pain of appen- dicitis; to this rule there are very few exceptions. At this time there is no special tenderness in the abdomen; indeed, as in intestinal colic, pressure "may relieve the pain. But usually within twelve hours the character of the pain changes; it is no longer diffuse and colicky, but becomes localized to the right iliac region, where the diseased appendix is found. The pain is now burning, constant, and intense. Simul- taneously with this localization of the pain to the right iliac fossa there develop both tenderness and rigidity, which also are confined to the region of the appendix. Palpation now reveals a normal abdomen elsewhere, but over the right iliac fossa the muscles (par- ticularly the right rectus) are rigid, and tenderness is so marked that even slight pressure causes extreme pain. This localized rigidity is the most important single symptom of appendicitis. Roughly speaking, all these symptoms of appendicitis are localized around McBumey's point, which was described by its author in 1891 as a point from one and a half to two inches distant from the anterior superior spine of the right ilium on a line drawn between this spine and the umbilicus. When this stage of the disease has been reached it is possible in all but the most exceptional cases to make an accurate diagnosis of appen- dicitis. The condition is clinically one of localized peritonitis, as described at p. 805, and that this is the pathological state is evident from the account of the pathogenesis of appendicitis already given. 852 SURGERY OF THE GASTRO-INTESTINAL TRACT Appendicitis is localized peritonitis; all the signs of this condition are present : tenderness and rigidity, arrest of peristalsis in the immediate vicinity of the lesion, local tympany from paresis and distention of the ileo-cecal coil of the intestinal canal; and persistent constipation. The development of complications should not be awaited before making an accurate diagnosis. In a small proportion of cases the attack does not begin with acute pain, but with a gradually increasing discomfort in the neighborhood of the appendix; and in such cases, the physical signs of appendicitis often develop without any nausea or vomiting. Hence it is, that in appendicitis as in all other acute abdominal lesions when the history of the case is atypical, it is safer to rely on the physical examination than on the history, in reaching a diagnosis. No mention has been made hitherto of the temperature, pulse, or leukocytosis, in connection with appendicitis. They are of_ quite secondary importance. Usually the temperature is slightly elevated from the first, and the pulse quickened, as in all febrile states. There also is leukocytosis in most cases, the white blood cells numbering anywhere from 10,000 to 40,000. The white-blood count is of more value in prognosis (p. 859) than in diagnosis. When the stage of localized symptoms described above has been reached, the disease pursues either one of two courses: It subsides, or complications develop. In the former case the pain gradually lessens; the tenderness changes to mere "soreness," rigidity disappears, flatus is passed normally, the temperature curve reaches the normal, and the leukocytosis gradually subsides. The course of such an attack lasts on the average from three days to a week. If the attack does not subside, complications develop; they are frequent and almost countless. Among the more important are perforation and gangrene of the appendix, and abscess formation or diffuse peritonitis with all its dire consequences. The symptoms, diagnosis, and treatment of these complications are considered at p. 857. Diagnosis. — The diagnosis of appendicitis usually is easy. It is the most frequent of all acute abdominal diseases, and should be ever in the surgeon's mind. In intestinal colic the pain is general and does not become localized to the region of the appendix; pressure relieves it; nausea and vomiting are by no means constant, and often precede the onset of the pain; active peristalsis is audible; and diarrhea is the usual outcome. At no period of the attack is there muscular rigidity. Fever is unusual. Leukocytosis is absent. In biliary colic the pain is situated in the right hypochondrium and often radiates to the right shoulder. A history of many previous attacks often is obtainable, and jaundice may have been present at some time. Tenderness and rigidity if present are confined to the gall-bladder area. If the patient is past forty years of age the attack probably is biliary, not appen- dicular. In acute cholecystitis the symptoms somewhat resemble those of biliary colic. Tenderness and rigidity are constant, but are con- fined to the upper right abdominal quadrant, unless the gall-bladder M'i'i<:si)i('iTis 853 IS (lisplaccd. TIu« clmnictcrislics by vvliicli ;iii enlarged Kull-hladdcr is nc.un.z,-,! an- stated at p. <)L'(). Jn renal colic from disease of the right kidney, the symptoms may elosely simulate those of ai)peii- dieitis, particularly when a ealcuhis is lod^vd j,, the ureter Yet tlie ra(hatiou of tlie pain, the urinary HikHuks, aiilete. The freciuency of second attacks of a])pendicitis is j^reat, and they are attended by all the dangers of the first. Even should no such acute attacks occur, the presence of the diseased organ and of the adhesions which surround it often seriously impairs the patient's comfort and may render him a semi-invalid; moreover, the appendix may undergo malignant change. Chronic Appendicitis. — The pathogenesis of this condition was dis- cussed at p. N41). The ftympioms are many and various. Pain is the most constant symptom and is one without which the diagnosis cannot be made accurately. In most cases the pain is localized to the region affected, but it may be referred through the pull of adhesions to various parts of the abdomen. Gastric dyspepsia is frequent, and may be the predominant symptom. The stomach, as W. J. ^Nlayo points out, is the mouth-piece of the gastro-intestinal tract. Disorders anywhere in this tract are constantly calling attention to their pres- ence through disorders of the stomach. This is true, of course, espe- cially of gastric and duodenal lesions; but it is equally true of gall- stones and of clironic appendicitis, as well perhaps as of other less frequent lesions. The characteristics of the tlyspepsia due to chronic appendicitis are sufficiently distinct to enable a diagnosis to be made in most cases. The gastric symptoms occur with no regularity as regards ingestion of food, nor is relief obtained by eating. Indeed, eating usually aggravates the indigestion, but with no constancy or regularity. The patient complains of general abdominal pain, mostly below tliQ umbilicus. The patient usually is about thirty years of age. Patients past thirty-fi\e years much more often suffer from dyspepsia due to gall-stones, and those past forty years from that due to gastric ulcer or its sequels. Apart from the symptoms of chronic appendicitis, a good deal of reliance should be placed on the history of the case, and particularly on the physical examination. Usually there will have been one or two attacks of abdominal pain or distress sufficiently acute to have laid the patient up for a day or so, even if not so acute as to have been recognized at the time as attacks of appendicitis. Even when such a history is lacking, deep palpation of the abdomen over the right iliac fossa almost invariably detects marked localized tenderness even when none is complained of by the patient. Treatment. — The treatment of the disease consists in removal of the appendix. Often this contains a fecal concretion, and evi- dences may be found of past inflammation within the appendix (strictures, obliteration of its tip), or without it (peritoneal adhesions, kinks, etc.). 864 SURGERY OF THE GASTRO-INTESTINAL TRACT Primary Carcinoma of the Appendix is found in about 1 per cent, of cases wliicli come to operation or necropsy. Without microscopical examination tlie lesion usually is overlooked. It causes no symptoms which suffice to distinguish it from clironic appendicitis, with which it often is associated. Its frequency is an argument for the removal of the appendix as an incident in the course of other abdominal operations. Tuberculosis of the Appendix is scarcely less frequent than carci- noma. If any symptoms are produced the\' are indistinguishable from those of chronic appendicitis, except when the tuberculous infection has spread so far as to give rise to the clinical picture of tuberculosis of the peritoneum (p. 815). The appendix should be removed unless the disease is so widespread as to make this unusually difficult. Intussusception of the Appendix has been recorded in a few cases. The symptoms are those of acute appendicitis and the treatment is the same. SURGERY OF THE STOMACH AND DUODENUM. Gastric and Duodenal Ulcer. — It is probable that these ulcers, as well as others in the gastro-intestinal tract, are toxemic in origin. In practically all toxemias there are gastro-intestinal ulcers, and in practically all cases of gastro-intestinal ulceration there is present some form of toxemia (Dieulafoy, Gandy, 1899). The toxemia is of infectious origin, and the infection may arise in a clironically inflamed appendix, in the biliary tract, or in some other situation which is readily overlooked. Oral sepsis usually is present, and no doubt has etiological relation; constant swallowing of pathogenic microbes impairs the vitality of the stomach, and its acid secretions render it more vulnerable, ^lechanical indigestion, from rapid eating ("bolting" unmasticated food), is another important cause. The earliest stage in these gastro-intestinal lesions is ecchymosis; then follow hemorrhagic infarct, slough, and hemorrhagic erosion; next is developed the "exulceratio simplex" of Dieulafoy; then comes the true ulceration with hemorrhagic borders; and then the final stages, perforation, chronic ulcer with thickened border and little tendency to heal, or a cicatrix. These local eflfects probably are due to the action of hemorrhagins, which erode the endothelial lining of the bloodvessels, and of mucolysins, which destroy the gastric mucosa. Ecchymosis, the first stage, is produced by hemorrhagins alone; when mucolysins also act an erosion is produced, and in time a fully developed ulcer will be formed, unless anti-bodies are formed by the organism to hold these cytolysins in check (Hort, 1908). These ulcers are not formed alone in the stomach and duodenum though they are most frequent here. Other similar lesions, not so apt to produce symptoms, may exist in the jejunum or ileum or large intes- tine, but they are comparatively rare. In the mucous membrane of the stomach there are small collections of lymphoid tissue, and these GASTRIC AM) DUODICNAL ULCER 865 arc in jfrcatcst iiuiuIht al()ii to 2), and of gastric ulcers those near the pylorus and along the lesser curvature of the stomach are much the most frequent. At first "acute," "round," or "open" in type, the ulcer through long duration becomes callous, with thickened borders; and if healing finally occurs, in part or wholly, the resulting cicatrix will distort the stomach, and perhaj^s cause pyloric stenosis. Acute Gastric Ulcer, or Open Ulcer, is not very frequent in this country. It affects especially anemic young people, especially women, from eighteen to twenty-five years of age, and is as much a symptom of their disease as the anemia itself. It is apt to give rise to hemorrhage and to perforation. The ulcers usually are multiple; are round; api)ear punched out of the gastric wall; and usually are from 0.5 to 1 cm. in diameter. Symptoms. — The characteristic symptoms are severe Inirning pain soon after eating, relieved by evacuation of the stomach either through the pylorus or by vomiting. The pain seems to be due to the increased acidity of the gastric juice caused by the process of digestion, as well as to peristaltic movements and mechanical trauma by the food. There is hyperacidity even of the empty stomach . Antacids thus relieve the pain. iVn area of tenderness in the epigastrium is commonly pres- ent, usually to the right of the median line; sometimes a similar tender area is found just to the left, more rarely the right of the last two dorsal vertebrae. Vomiting is frequent, often being self-induced to relieve pain. The vomitus often is streaked with blood, and quite independently of the ingestion of food hematemesis may occur. Pro- fuse and prostrating hemorrhage usually is due to an erosion or an exulceration; more moderate bleeding, especially if frequently recur- rent, generally is due to the round open ulcer. Chronic Gastric and Duodenal Ulcer; Cicatrizing or Callous Ulcer. — This may be a later stage of the open ulcer already described, but it seems clinically often to have been chronic from its commencement, whatever its pathological origin. It is a much more frequent disease in this country. It is this type of ulcer which is more often duodenal than gastric. Mayo has established the position of the pyloric vein 1 The normal acidity of the gastric juice is equivalent to 0.48 per cent, hydro- chloric acid. If a patient is reported to have a gastric acidity of 60, this signifies that there is hyperchlorhydria. If, on the other hand, the total acidity is reported as .30 or 20, the acidity is clearly below normal. The "free" acid of the gastric juice normally varies between 0.1 and 0.2 per cent. 55 866 SURGERY OF THE G ASTRO-INTESTINAL TRACT as the dividing line, and classes the portion of the duodenum above the bile papilla as gastric rather than intestinal in nature. The ulcer, which usually is single, has thickened borders, and is quite irregular in outline. Cicatrization leads to contraction, and jiyloric stenosis (p. 868) is the most frequent result. If the ulcer is situated on the lesser curvature, it often extends on both anterior and posterior walls of the stomach (saddle ulcer) ; and its cicatrization may produce hour-glass sfomach (p. 871). The chronic inflammatory changes around the periphery of the ulcer are frequent forerunners of carcinoma of the stomach (p. 873). Symptoms. — These last a long time before relief is sought from surgery, so that the patients usually are thirty-five to forty years of age or older when first seen. The affection is commoner in men than in women. Symptoms of dyspepsia overshadow everything else. These dyspeptic attacks, characterized by flatulence, pain, palpitations of the heart, epigastric distress, belching, sour eructa- tions, nausea and even vomiting, occur in periods which last several weeks at a time. During the intervals the patient suffers less, but is not entirely free from symptoms. The pain and distress do not begin until tliree or four hours after meals, and are relieved by ingestion of more food (himger-pain of INIayo Robson). This is because the excess of acid is neutralized by food. Patients are unwilling to go without food for more than a few hours at a time. This constant and regular recurrence of gastric dyspepsia several hours after meals is particularly characteristic. The dyspepsia due to chronic appendi- citis (p. 863) is both inconstant and irregular in its occurrence, and is not relieved by eating. In chronic gastric or duodenal ulcer, how- ever, the distress from indigestion may finally become so extreme, that a patient will be unable to eat his full meals. He may be reduced to carrying a bottle of milk around with him, taking a sip every little while, to relieve the burning sensation in his stomach. Hemorrhage, as has been remarked, is less usual in chronic than in acute ulcer, and rarely is large in amount. If the ulcer is duodenal, blood in the stools (melena) is more frequent than hematemesis; the bleeding may be occult or visible to the naked eye. Physical examination is of much less assistance at this stage of the disease, than later, when pyloric obstruction has developed. Tender- ness is rather diffuse; and occasionally a mass may be felt in the pyloric region, and may be mistaken for carcinoma. Prognosis and Treatment of Gastric and Duodenal Ulcer. — Hemor- rhage kills about 5 per cent, of patients, and perforation about 15 per cent. Of the 80 per cent, which remain, prompt, efficient, and pro- longed medical treatment will cure perhaps three-fourths; but this cure seldom is permanent. From 30 to 50 per cent, of patients so cured have relapses, and though they may be "cured" a number of times by resort to medical treatment, the cure usually is attained with greater difficulty and is less lasting, after each new relapse. ]\Iean- while the patient is subjected to the danger of hemorrhage and per- GASTUIC AM) Dl'ODENAL ULCER