RAGt4 C3Q- Columbia ^nitjer^fftp intlieCitpoflmjgork College of ptpsiictans: anb ^urgeon£( ililirarp ^^^5^P^ Gipt or RHOOt ISLAND MEDICAL SOCIEry Digitized by the Internet Archive in 2010 with funding from Open Knowledge Commons http://www.archive.org/details/statecontroloftuOOchap FiSKE Fund Prize Dissertation. No. XLIV. STATE CONTROL OF TUBERCULOSIS. CHARLES V. CHAPIN, M. D., Superintendent of Health of the Chy of Providence. PKOVIDENCE : Snow & Farnham, Printers, 1900. THE Trustees of the Fiske P\incl, at the annual meeting of the Rhode Island Medical Society, held at Providence, Sept. 0, 1900, announced that they had awarded a premium of two hundred dollars to an essay on " State Control of Tuberculosis," bearing tlie motto : " Festina lente." The author was found to be Ciiari.es V. Chapin, M. D., of Provi- dence, R. I. GEORGE D. HERSEY, M. D., Providence. GEORGE F. KEENE, M. D., Howard. WILLIAM R. WHITE, M. D., Providence. Triditees. HALSEY De wolf, M. D., Providence, Secretary of the Trustees. The State Control of Tuberculosis. To successfully control a disease it is necessary to know how it is caused. For a century or more, many acute observers have been convinced of the contagious character of tuberculosis. Experiments were long ago imdertaken to prove its communicability, and some of them, particularly those of Villemin, were successful. The intelligent medical ^vorld was not, therefore, un- prepared for the discoveries of Koch. By him was discovered the essential factor in the causation of the disease. His experiments were a complete demon- stration that the disease we are considering is due to the action upon the tissues of the tubercle bacillus. The bacillus is the cause of the disease. Scores of competent observers at once attempted to prove or disprove Koch's views. This is the proper fate of every important discovery and of every alluring error. Eighteen years have passed, and no person able to judge denies the causative relation of the bacillus to the disease. The definition of the disease is made by the facts. Whatever abnormal condition is produced in the tissues by the bacillus is tuberculosis. DISTRIBUTION OF THE DISEASE. There are various forms of tubercular disease occur- ring among both men and animals. Of the forms occur- ing in the hmnan species, phthisis is the most common. It is generally said to cause one-seventh of all deaths, but that, at present, is scarcely true, for, owing to the 4 THE statp: control diminution wliicli has, of recent year.s, taken place, it does not, luider favorable conditions, cause more than one-ninth or even one-tenth of the deaths. It is diffi- cult to determine just what proportion of tubercular deaths is due to other forms. The recent Royal Com- mission considered that al)out one-quarter of tubercular diseases are not phthisical. In Providence, however, probably not over 15 per cent, are non-phthisical. It is only in infancy that non-phthisical forms are the most prevalent. In Massachusetts, under one year, the non-phthisical are to the phthisical as 116 to 11, and Ijetween the first and fifteenth year, as 61 to 37'. The non-phthisical forms of the disease Ave are consider- ing are retiu^ned, sometimes, as " tuberculosis," some- times as tubercular meningitis, laryngitis, etc. ; again, as hydrocephalous or lu])us. Diseases of the bones and joints and intestinal diseases, especially in young chil- dren, are very commonly due to tubercular infection. In this connection, it must be remembered that the deaths do not by any means represent all the cases. Tuberculosis is not infrequently recovered from, though it leaves its traces in the organism. Marks of tuber- cular infection are frequently found at the autopsy of persons who have died of other affections. Knopf says that traces of tuberculosis are found in 25 per cent, of all such autopsies. In the New York hospitals it runs as high as 30 per cent., and in Vienna, where the disease is particularly prevalent, the marks of tuberculosis are said to l)e found in (S5 per cent, of all autopsies. A very large number of species of the lower animals are also suljject to tuberculosis, particularly domestic animals oi" wild animals kept in confinement. OF TUBERCULOJSIS. 5 To tiiljerculosis acquired iiatiinilly. the bovine species appears to be more susceptible than are other animals. Next in susceptibility among the domestic animals are swine. Goats and fowls also contract it, and sheep sometimes have it. It is very readilv inoculated into rabbits and guinea pigs. Parrots and canaries have been known to have it, but it is very difficult to pro- duce it in sparrows. The carnivorous animals are very slightly susceptible, though wild animals kept in con- finement, as lions and tigers, occasionally contract it. As a rule mammalia are more susceptible than the other vertebrate classes. Birds come next, and it has only recently been discovered that fishes sometimes have this disease. Even in the Ijovine species, tuber- culosis is not uniiormh^ distributed. The statistics of the Leipsig slaughter-house for 1895 showed that of oxen 28.14 per cent, had tuberculosis ; of heifers, 20.35 per cent. ; of cows, 43.51 ; of ])ulls, 23.83, and of calves, 0.18. It would be of very great interest to know just how ex- tensively tuberculosis prevails among the herds of this and other civilized countries, but we have no accurate statistics, at least, for this country. It is probably much more common in certain parts of Europe than it is in any part of tbe United States. It is said that 27 per cent, of all animals slaughtered in Saxony have tuberculosis. No such figures have been obtained in this country, though, in Philadelphia, it is said that a year or two ago 20 per cent, of the slaughtered animals were infected. In the New York slaughter-houses, 7 per cent, have been found infected, and, at the Brighton abattoir, 5 per cent, of Eastern cattle. In Massachusetts, wdiere the tuberculin test is required 6 THE STATE CONTHOL for all animals imported into the State, it is said that 10 per cent, of the animals tested ])rove to he tuher- ciilons. There is ahnost no tnherculosis among the eattle on the ranges in the West, and the most is found among the dairy herds which sn])ply the Eastern cities. Veterinarians seem to he very generally agreed that tuberculosis among cattle has increased considei'ahly during the last few years, at least until steps began to be taken for its eradication. It has been suggested that the tuberculosis of man and of the other animals may not be identical. The bacilli which are found in the lesions of the different species are not always exactly the same. There are slight morphological and cultural differences between the bacilli usually found in man and cattle. The bovine bacilli are usually slightly shorter and straighter, and their growth upon artificial media is less luxuriant, and these characters are quite consistent through several generations of artificial cultures. There are some differences, also, in regard to the degree of viru- lence of the different forms. Theobold Smith, who has given special attention to this subject, has rarely found the bovine type in human subjects. He is, however, far from holding that the different types may not pass from one species to another. Recent bacteriological work seems to show that the morpho- logical and physical characters of most species of bacteria can be considerably changed, usually slowly, sometimes raj^idly, by change of environment. Thus, although ordinarily the tubercle bacillus does not grow at a temperature below 98*^ F., it can be made to do so by careful manipulation, hy gradually reducing the temperature for successive generations. The general OE TUBERCULOSIS. 7 opinion seems to be that such slightly different forms as the limnan and l)ovine bacillus may readily pass one into the other ; moreover, as will be seen, there is con- siderable evidence to show that the disease is fre- quently transmitted from animals to man and not rarely, vice versa. There are many who go so far as to think the evidence shows that almost all human tul^er- culosis is derived from the lower animals. One argu- ment for this, which has been elaborately presented, is that the prevalence of the disease in the human and bovine species is co-extensive, and that human tuber- culosis is not found where there are no domestic animals affected with this disease. This argument will not, however, bear close investigation, for right in our own section of the country, at Nantucket and on Cape Cod, tuberculosis among cattle is very rare, but is ex- tremely common among human beings. While the bacillus is the essential cause of this dis- ease, there are, of course, many other factors in its production. There are, probably, differences of indi- vidual susceptibility to all infectious diseases, and this difference appears to he very marked as regards tuber- culosis. It has long been believed that a poorly nourished body is one of the chief factoi's in the caus- ation of individual cases of the disease. There are certain physical characteristics which are difificult to define, but not so dithcult for the practiced eye of the physician to recognize, which are indicative of a tuber- cular disposition. It is through the inheritance of such characters that heredit}' has its share in the spread of this disease. The disease itself is rarely in- herited, but the susceptibility to it frequently is. It is always difficult to demonstrate the relative import- THE STATE CONTROL aiice of heredity and eiiviroiinient, but ino.st physicians have seen so many cases where tlie influence of heredity appeared to be very great, that most are con- vinced that this is a very important factor. Law re- ports an interesting case where he found eleven cows of a certain herd infected with tuberculosis. These eleven were all of one family, distinct from the rest of the herd. The actual inheritance of tuberculosis does sometimes take place. Calves killed immediately after birth are sometimes found to be tuberculous. In the Munich slaughter-house this is found only once in 100,000 cases, and in Lyons the proportion was not much greater. Most European veterinarians consider it a great rarity. It appears to have been seen more often in the United States. The Maine cattle commis- sioners report having met with it in sixty cases. What are called unhygienic surroundings, over- crowding, impure air, especially dust-laden air, lack of sunlight, insutficient clothing, and improper food are all good friends of the tubercle bacillus. The State may do much to improve the conditions of life, and, in this way, indirectly control the spread of tubercular disease, but it is not this indirect form of State control which will be considered in this paper. METHODS OF EXTENSION. That tuberculosis is contagious was incontestably demonstrated by Koch. The difticulty of demonstrat- ing the contagiousness of a disease clinically is very great. For years physicians have felt that such evi- dence was very strong, and, not long since, the com- mittee on collective investigation of the British Medical Association attempted to secure evidence which would OF TUBERCULOSIS. 9 satisfuctorih" prove or disprove the point at issue, ))ut, altli(nigh several hundred cases were reported, it was sliown in an ahle pjiper l)y Langstaff that they were not much more numerous than the coincident affection of the two persons could be expected to occur, accord- ing to the law of chance. It has, how^ever, been proved beyond question that among animals the dis- ease ma}^ be and is transmitted from one individual to another. The identity of the lesions in man and animals, and the fact of the universal presence of the bacillus in these lesions renders it certain that tuber- culosis in man also is a contagious disease.- There can be no question that tuberculosis is only caused hy the tubercle bacillus, and that the tubercle bacillus does except under extraordinary conditions, not, grow out- side of the human body. In order to grow tlie tubercle bacillus, it is necessary to exercise great care in the preparation of the culture medium. Furthermore, growth will very rarely take place except at the temperature of the body. The conditions are such that it can be said to Ije strictly ])arasitic in its habits of life. If any animal becomes infected, the germs must have been derived mediately or immediately from some other animal. While the bacilli do not grow outside of the l^ody, they may re- main alive for a considerable length of time. They are not, however, so resistant to destructive agencies as are many bacteria. Exposure to sunlight very speedily destroys them, sometimes in a few minutes. Drying, however, does not destroy them. Dried sputum has been shown to retain its virulence for three months, and doubtless, at times, will retain it for a much longer period. The bacillus is readily 10 THE STATE COXTROL killed by beat, exposure to a temperature of 00'^ C. for 15 minutes proving fatal. It is, bowever, quite re- sistant to dry beat. It is killed by disinfectants of ordinary strengtb, but tbe action of corrosive sublimate upon sputum requires a strengtb of 1 to 500, as it forms inert compoiuids witb tbe allnmiinous matter of tbe sputum. Tbe presence of tbe tubercle bacillus in tbe dust of bospitals, cburcbes, tbeatres, scbools, dwellings, and streets bas been mucb discussed. A considerable number of investigations bave been made to determine its presencein different localities. Some years since, Webb, in Pbiladelpbia, found it in tbe air of places of public assembly. Hance found it in tbe air of Adiron- dack sanatoria, killing 5 out of 25 Guinea pigs wbicli be inoculated. Gardiner did not find it in 8 tests made at a Colorado Springs botel. Tbe most careful and complete experiments were made by Cornet. Tbe following table shows tbe results of bis work : Places fko.m w uki Sami'les of DrsT WEKE Taken. In the seven hospitals In the three insane asylums.. . . In two prisons Inhalation experiment room. . . Private patients Poliklinik, orphan asylum, etc Surgical halls Streets and hygienic institute. . Streets alone Totals : .. 892 59 94 33 14 4 170 28 8 41 196 !£ cS C O !3-~ — 0) C o ^ S •O Si 2 oj QJ C 72 19 6 2 125 14 1 16 255 76.6 67.5 42.0 50.0 73.5 50.0 12.5 39.0 55.0 14 8 2 25 14 65.05 137 OF TrBERCULOSIS. 11 From this table we can make the dediietion that the danger to the inocuLated jinimals of tnbercular infec- tion was in tlie hospitals 47.6 per cent., in the insane asylmns 17.G, and in private dwelling houses of con- sumptive patients 43.6. Cornet's experiments showed that invarial)ly, where the tul)ercle l)acillus was found the patients did not restrict themselves to the use of a spit-cup, but expectorated, also, upon the floor or into a pocket handkerchief. He succeeded only in a single instance in making an animal tul^erculous where the patients had surely restricted themselves to the use of the spit-cup. Twenty-nine of his samples of dust were taken from places not especially frequented l^y tuber- culous persons, such as general hospitals, an orphan asylum, the hygienic museum, public stairways, and, in nine instances, from streets. These samples were inoculated upon 873 animals, not one of which became tuberculous. These experiments tend to make it quite certain that the tubercle l^acillus is not very widely distributed. There is not much chance of meeting with it except in the close neighborhood of a consump- tive or in apartments wdiich have been for some time occupied by a consumptive. Further investigations of the distribution of the tubercle bacillus would be very desirable, but from those already made and from what we know clinically of the spread of this and other com- municable diseases, it is entirely likely that the con- clusions of Cornet would be fully verified. Strauss examined the saliva of a number of persons who had the care of those sick wdth phthisis, and found bacilli present in a few of them. It has been demon- strated by very many observers that the expired breath contains no bacteria of any kind. AVith the conditions 12 THE STATE COXTUOL that pre\ail in coughing, sneezing, and sometime.s even in talking, it is otherwise. Under such conditions there appears to be a fine spray thrown out, in the droplets of which bacteria may be found, and tubercle bacilli have thus been shown to be given off from phthisical patients. This spray, however, extends only a few feet from the patient. Experiment, then, seems to shoAv that ordinarily quite close contact is necessary for contagion in this disease. Clinical evi- dence also supports this view. Of course in the majority of cases of marital contagion wdiicli have been recorded, the intimacy was close. Of 213 cases of probable contagion collected by Martin, one-half were marital. Cornet's investigation of the Catholic Nurs- ing Orders in Germany, before precautions were taken to prevent contagion, showed that a very large number succumbed to this disease. Of 2,099 deaths, 1,320 were due to tuberculosis, and of course in all these cases there was close contact between the nurse and the patient. The evidence, then, seems to be very strong that the tubercle Ijacillus is not widely distributed outside of the body, that it is not found in the air except close to tlie patient, and not then in any quantity if proper precautions are taken. Contagion is found only in the air close to the patient, on the patient himself, and on articles wdiich the patient or his secre- tions have touched. Prol)ably the same conditions are necesary for contagion from animals. There are three avenues of infection : , First, tkroiKjh the skin. There are a number of cases of persons who have been inoculated through the skin. The celebrated OF TUBERCULOSIS. 13 Laennec died of pulmonary tiiberculoisis which was thought to be contracted through the accidental inocula- tion of his finger at an autopsy. A more recent case and one concerning which there is little doubt was reported by Pfeiffer, who tells of a veterinarian whose finger was inoculated, whose joints later became involved, and who finally died of the pulmonary form of the disease. Law and Ravenal both report cases of the accidental infection of the hands of veterinarians, and in the case reported by the former, the extension of the disease was only prevented by amputation. Knopf had a similar case in a nurse who l^ecame inflected while dressing a tuberculous wound. Ernst rejDorted a case of infection of the tongue. Heron, in evidence pre- sented to the Connnittee on Collective Investigation, in 1890, reported seventy-three articles dealing with this subject. A considerable number are also reported by Senn in his surgery. Lindeman, Jacobi, and Knopf report a numl^er of cases of infection through the rite of circumcision. There are also on record cases due to the common practice of tattooing. In can thus be seen that the danger of infection through the skin is a real one. Nevertheless, the evi- dence shows that the danger is very slight, and may be neglected in any measures undertaken for the state control of the disease. Second, throiKjh the respiratory tract. It is generally believed that this is by far the most common avenue of infection. This view is based chiefly upon the facts that the pulmonary is the most common form of the disease, and that the lungs are, in such cases, involved to a very much greater degree 14 THE STATE CONTROL than are other organs. It is pro])a])le that in the main this reasoning is correct. But it does not necessarily follow that because the lungs are chiefly involved that they were the seat of the primary infection. Wood- head has shown that infection through the intestinal wall may leave very few traces there, the most im- portant lesions being subsequently found elsewhere in distant organs, such as the thoracic glands. From the time of Koch, many experiments have been tried to produce pulmonary tuberculosis l)y the inhalation of dust containing the living bacilli. Most of these experiments have been unsuccessful. The attemj)t has also Ijeen made to induce it by the inhala- tion of spray, such as was referred to as given off from consumptive patients during sneezing and coughing. These experiments have been more often successful, but not invariably so. It seems to be quite certain from the experiments of Cornet that have ))een referred to, and from the observations of many careful investi- gators, that pulmonary infection is not readily induced. The breating of a few bacilli by a healthy person is not likely to cause the disease. Chance contact with bacilli in the dust of the street, which has Ijeen much dreaded, probably rarely gives rise to the disease. Most of those who have studied the contagion of this disease clinically, as tlie Committee on Collective In- vestigation, Heron, Martin, Russell, and Cornet, believe that close and prolonged contact is necessary, in most cases, to produce infection. Infection is not carried far by the air. This accords with the known facts in regard to the transmission of other diseases. Scarlet fever and diphtheria do not pass from one tenement to another in the same house unless there is an actual OF TUBERCULOSIS. 15 passage of infected persons. The carrying of con- tagion from the sick to the well by a third person is not common. Physicians rarely carry contagions dis- eases. It seems most reasonable to jjelieve that the majority of cases of consumption are due to primary infection of the pulmonary tissue, but this is by no means proved. It may be that future investigation may change this view. Even now, there are man}' who hold to the contrary. Knopf believes that fully as many cases of tuberculosis receive their infection through the alimentary canal as through the respira- tory mucous membrane. Third, through the a/lnteutari/ tract. Medical literature contains the record of many cases of tuberculosis which are presumably due to infection • through the alimentary canal, usually from the in- gestion of milk supposed to be tuberculous. Some- times, however, as in cases reported by Sherman of San Francisco, the infection was caused by kissing or putting infected articles in the mouth. In many of these reported, the evidence of the source of the in- fection was bv no means certain, and in not a few of them, infection through the alimentary canal was a possibility rather than even a probal^ility. Ernst re- ceived 1,013 answers to a circular sent out to physicians and veterinarians, asking for reports of cases of tuber- cular infection through the medium of milk. Although (juite a number of cases were reported, it was not possible in many of them to exclude, with any degree of certainty, other sources of infection. It is thus seen that clinical evidence of infection through the 16 THE STATE CONTROL alimentary canal is not very strong. But such a result might well l)e expected. It is ditticult to trace con- tagion in any disease, and particularly so in tubercu- losis, a disease which is slow in developing, and which is extremely common. There is certain statistical evidence which indicates that infection frequently takes place through the ali- mentary canal, probably by the ingestion of milk. Tubercular disease of the digestive organs is much more frequent among young children and particularly infants under the age of one year than at any other age. Such children, of course, live largely on a milk diet, and if tuberculosis is transmitted through the medium of milk, we should expect intestinal and similar forms of the disease to be more prevalent at these ages. Again, statistics show that intestinal forms of tuberculosis have not, of late years, diminished nearly as much as has the pulmonary form. The re- port of the Royal Commission states that tuberculosis among children under one year of age has actually increased in England and Wales. In most places, how- ever, cases in infants have diminished somewhat in frequency. It is not, of course, to be assumed that all cases of tuberculosis in young children are due to milk infection. Yet as there is good reason to believe that tuberculosis among dairy animals has of late years in- creased, the fact that tuberculosis retains a stronger hold in infancy than in later life, tends to support tlie view that, in the young, milk infection is no incon- siderable source of the disease. The following table illustrating the distribution of the different forms of tuberculosis in Glasgow, also throws some light on this sul)ject : OF TUBERCULOSIS. 1890-5. GLASGOW Death Rates Per 100,000. 17 tr. < •2 Other Tubercular Diseases. All Tubercular - Diseases. i CORRECTED FOR AGE DISTRIIU'TION. City Average of three districts with (1) Highest death-rate from Phthisis (2) Phthisis death rate near- est mean of city (3) Lowest Phthisis deatli- rate 2,336 3,256 2,197 1,692 230 328 213 157 91 125 95 67 321 454 309 225 28.3 27.5 30.9 30.2 It is seen that all tubercular deaths most prevail where the general death rate is greatest, and there also phthisis is most prevalent, but the other tubercular diseases are relatively less prevalent than in other dis- tricts where there is not only less phthisis, but a much better condition generally, as is indicated by the general death rate. It can scarcely be maintained, therefore, that the other forms of tubercular disease occur as a direct result of the frequency of infection afforded by the prevalence of phthisis. Chalmers who prepared tlie above table states that in the l)etter class districts there is a greater consumption of milk than in the slums, where the other tubercular diseases form a relatively smaller proportion of the tul)erculous death rate. Woodhead states that of 127 cases of tuberculosis in children, in which autopsies were made, the mesenteric ulands were involved in 100. He assumes from this 18 THE STATE CONTHOL that the source of iiit'eetioii in these 100 cases was, in all probability, through the intestines. In fact, in many cases, he conld trace the infection from the in- testinal wall up through the mesenteric glands to distant organs of the Ijody. Woodhead also believes, from pathological e\idence, that infection not rarely takes place through the tonsils, this often being the soiuTe of the tul)ercTdar infection of the cervical glands. A great deal of experimental work has been done upon the jiroduction of tuberculosis hy way of the alimentary canal. A good many examinations have been made to determine the frequency Avith which tubercle bacilli may he expected in the milk supply. There has been much discussion as to the occurrence of the bacilli in the milk of tul)erculous animals. It has been claimed hy some that they will not ])e found in the milk unless the udder is iuAohed ; Init it has been shown that this is not true. Milk is much more likely to Ije tuberculous when the udder is seiiously involved, Init it does occur when no signs of disease can be detected. Ernst examined microscopically the milk of thirty-six animals, which were tuberculous but had sound udders and found bacilli in the milk of twelve. They were found equally in the milk itself and in the cream. In fifty-six samples of milk and thirtv-three sami)les of cream, taken from the general supply of the Cit}' of Boston, no bacilli Mere found on miscroscopical examination. The most certain way of detecting the presence of tubercle bacilli in milk or, in fact, in any material is by inoculating the same into animals. Ernst found in twenty-five inoculation ex- periments performed with milk from the Boston supply, OF TIBEIICULOSIS. 19 tliut three gave jKJsitive results. Kaiitliaek, experi- menting in Camljridge, England, found infection in nine out of sixteen dairies supplying that town. The milk, however, was not very thoroughh' impregnated, as only a very few of the animals inoculated succmnljed to the disease. It has been shown experimentally in reii;ard to the tuljercle Ijacillus in milk as, indeed, it has to the cultures of many other bacteria, that the greater the dilution and the smaller the dose, the less the chance of infection. Kanthack. as well as p]rnst, has shown that the Ijacilli are found in cream as well as in the whole milk, l)ut when milk is put through a centrifugal machine, the larger ptirt of the bacilli are renio\ed in the sediment. Experiments in Germany have shown that butter may contain tubercle bacilli. A number of other experimentors, as well as Ernst, "have found 1)acilli in milk, when the udders were apparently healthy, and. in fact, when tuberculosis could only be detected by the tuljerculin test. It must l)e admitted, then, that we have pretty strong- evidence that if a dairy herd has in it tuberculous animals, the milk fnjm that herd stands a very good chance of being infected. The more disease there is in the herd, and the farther advanced it is, the greater the danger. ~- The fact that tul)ercle bacilli are found in milk and may, by injection into the lower animals, cause tuber- culosis, does not prove that milk would cause the disease if taken into the alimentary canal. Of course, many feeding experiments have Ijeen undertaken with milk and other products from tuberculous animals. These have not always been successful. Smith, Law, Nocard, 20 THE S'I'ATE COXTL'OL and McFadyeaii coidd not infect rabbits and gninea pigs by feeding tbem witb milk winch was known to be tubercnlons. Pencil, for two months, fed two pigs with milk that, by injection, prodnced tnbercnlosis in rabbits, withont prodncing any effect npon the pigs. Gerlach also was sometimes snccessfnl and sometimes not. On the other hand, many feeding experiments have been snccessfnl. Ernst, nsing milk from tuber- cnlons animals with apparently healthy udders, pro- dnced tu])erculosis in two out of forty-eight calves fed with it. He also infected five out of twelve pigs ; and, in another series of experiments, eight out of tAventy- one calves. Law reports three calves which had milk from sound udders, but became tuberculous. Pearson fed pigs with milk known to be tuberculous, and the animals apparently got fat upon it, Init wdien killed were found to Ije infected. He saj^s instances are not rare in which calves and swine fed with skim milk from a creamery, have developed tul^erculosis on farms that are otherwise free from this disease. The evidence, then, seems to ))e that milk of tuber- culous animals is quite likely to be infected, and that if infected it frequently produces tuberculosis in other animals, even of a different species, wliicli partake ui it. If milk can infect human lacings as it does calves and swine, it is certainly dangerous to use in a raw state the milk from tuberculous animals. While we have no incontrovertible evidence that bovine tul)er- culosis is thus transmitted to man, it is extremely probable that it is so. We certainly have very little evidence that it is not, and it would require prett}- strong evidence to show that a disease which can l)e carried over from cows to swine, rabbits, guinea OF Tl'BEROULO.SIS. 21 pigs and iiiaiiy other species, cannot he transmitted to Mian. There has jjeen a great deal of discussion as to the danger from the nse of meat from tuberculous animals. As the tubercle ))acillus is killed by a moderate deo;ree of moist heat, we can probably safely assume that, in the majority of cases, even if Ijacilli are present in meat, they will be destroyed by cooking. Experi- ments, however, to substantiate this view, are much to ])e desired. In cases where the lungs chiefly are in- volved and the disease has not progressed too far, there is not much likelihood of the muscles being in- fected. In fact, it is very unlikely that the muscular tissue itself will be. infected at all, but when there is a tendency to generalization of the disease, the small glands between the muscles or their fasciculi may be involved. In such cases^ it would be dangerous to eat the meat in a raw state. Feeding experiments have been conducted upon animals with little positive re- sult. Pencil succeeded in infecting two pigs, but only after feeding them for v. long time. Nocard was un- successful, as also were Touissant, Chaveau, Arloing, Martin, and Yallin. Perroncito fed eighteen pigs for from three to five months witli condemned tuberculous meat, but none of them were mfected. It would appear that the danger of infection by meat of tul)ercidous animals, at least unless the disease has progressed very far and is much generalized, is not very great. This view is held by many leading veterinarians. It is the practice of many not to condemn the flesh of tuberculous animals wlien the disease is circumscribed. In Saxony, the govern- ment inspectors permit the sale of the larger portion 22 THE .statp: control of the llesli of tuhcrculoiis ;iiiiiiials killed at tlie ahat- toirs. This meat, however, is sold on its merits as eoming from tiihereuloiis animals. At the Brighton abattoir, a considerable ])()rtion of the tnberculous ammals their slaughtered are allowed to go upon the market. METHODS OF CONTROL ALREADY ADOPTED. Notificntion. An important step in the control of other infections diseases is the report of cases of the disease to the sanitary authority. This is desired, in order that the cases may be studied and more may l)e leai-ned of the way in which the diseases are spread, and, in order that any necessary methods of restriction may be applied to each individual case. It would appear that notification is as necessary in tuberculosis as in other diseases. In this country, notification has been I'e- quired in a numljer of states and cities. Sometimes it applies to phthisis alone, and sometimes to all tuber- cular diseases. Notification was first required in the City of New^ York, and, at present, is a requirement of the State law in Maine and Michigan, and of the nruni- cipal regulations of Alameda, California ; Buffalo, Cin- cinnati, the City of New York, Salt Lake City, and Yonkers. In these regulations the requirement ap})lies only to i)hthisis. Tuljerculosis is to l)e reported by the State law of Washington and by the regulations of Asbury Park, Minneapolis, San Francisco, and Syracuse. A recent decision of the Supreme Court of Michigan has affirmed the validity of the law in that state. The followinjj: is the rule in the City of New York : OF TIBERCULO.SIS. Zo City of Xew York, Sanitary Code, 1899, Section -ui : Section lo^J. That pnhnonary tuberculosis is herein' dechired to 1)6 an infectious and communicable disease, daiijierous to the public health. It shall be the duty of every physician in this city to report to the Sanitary Bureau in writing the name, age, sex, occupation and address of every jierson having such disease who has been attended by or who has come under the observation of such physician for the lirst time, within one week of such time. It shall also I>e the duty of the commissioners or managers, or the jirincipal, superintendent or physician of each and every public or private institution or dispensary in this city to re})ort to the Sanitary Bureau in writing, or to cause such report to l)e made by some })ro}»er and competent ]>erson, the name, age, sex, occupation and last address of every person afflicted with this disease who is in their care or who has come under their obser- vation within one week of such time. It shall be the duty of every jierson sick with this disease and of every person in attendance upon anyone sick with this disease, and of the authorities of public and private institutions or dispensaries, to observe and enforce all the sanitary rules and regulations of the Board of Health for preventing the spread of pulmonary tu])er- culosis. These laws and regulations are not Avell enforced. The Secretary of the State Board of Health of Michi- gan informed the writer that probably not one-cjuarter of all the cases appearing in that state are reported, and the board of health of Buffalo report that notice is rarely recei^^ed of a case except when a physician sends in sputinn for examination. In Michigan, whenever a case of consumption is reported from a town, the health officer is required to fill out a Ijlank, stating a large nmnber of facts in regard to the history of the case, possible sources of infection, and methods taken to ]'estrict the disease. On the death of the patient, or re- covery, if recovery takes place, another and final report 24 THE STATE (ONTKOL is to be made, giving fucts of inteniiediate history and whether or not disinfection was done. No verv valu- able results have, as yet, been obtained from these investisrations, as onh* a few of the rm-al health officers can be expected to 1)e skilled enough to investigate the cases properly. In New York City, careful record is kept of all cases reported, and, owing to the active interest taken by the health department of that city, more cases are reported there than elsewhere, so that, of late, the number of cases reported has exceeded the number of deaths. A careful record is kept of all cases, and their location is also noted on a map. A study of this map has shown that phthisis prevails to a much greater extent in some districts, and in some houses, than it does in others. Notification presupposes correct diagnosis. It is generally admitted that the examination of the sputum for tubercle bacilli is a great aid to diagnosis, though it is to l)e feared that many physicians place too much dependence upon a single negative finding. To assist plivsicians, many states and cities olf'er laboratory facilities for the examination of the sputum. Education. A great deal has been done, during the past ten years, to educate the public to a knowledge of the contagiousness of tuberculosis. Prol)aldy a large pro- portion of intelligent people now imderstand that tul)erculosis is contagious. A large part of this work of education has been carried on h\ public health officials, particularly those engaged in laboratory work. It is to be feared, however, that some of the teachingr has oone farther than the facts would warrant. x^ '^'^" c OF TI'BERfrLOSIS. ZO It is certain that tuberculosis is contagious, but, as we have seen, the exact path of infection is not perfectly known. Nevertheless, dou'inatic statements have been verv common as to the great danger of breathing tuberculous dust, of drinking tuberculous milk, and of eating the iiesh of tul)erculous cattle. It is true, however, that most of the extravagant statements in regard to these matters have not emanated directly from the Ijacteriologists. The pul)lic press, and pseudo- scientists generally, have sometimes misunderstood the meaning of the work of scientific investigators, and have made too much of what are, perhaps, the least important patlis of contagion in this disease. The daily press is of great assistance in sanitary education, but its powers should be called into play with consider- able care. One of the most common and useful means of education in such matters is the distribution of cir- culars of information. Such circulars, explaining the nature and methods of the spread of tuberculosis, have Ijeen issued hy many health officials and l)y the societies for the suppression of tuberculosis. One of the first and best of these circulars was that issued by the Board of Health of New. York City. At present, such circulars are issued by the State Board of Healtli of California, Colorado, Connecticut, Delaware, Indiana, Iowa, Kentiu^ky, Maine, Massachusetts, Michigan, New Hampshire, New Jersey, New Mexico, New York, Ohio, Rhode Island, South Carolina, Tennessee, Texas, \^ir- ginia, AYest Yirginia, and Wisconsin. They are dis- tributed by many local lioards of health in these states m\(\ have been issued by cities outside of the states mentioned, as St. Paul, Minneapohs, Chicago, St. Louis, and Philadelphia. In New York City they are sent to 26 I'lIE STATE CONTROL the physicians for (Hstrihiition to their patients, and tliis method is probaljly followed in most cities. In Buffalo tliev are sent to all cases reported, or to tlie friends of tlic patient. In New York City the sunnnei' corps of physicians who visit among the poor, distri- bute some o(),(JO(J annually. In Brookline, Mass., one is sent to every family in the town. In Minnea])olis one form of the circular is printed upon a card which is to be hung in the room occupied by the patient. It must be confessed that many of these circulars are not very ^vell prepared, exaggerate very much some of the means by wliich the disease is spread, pass lightly o^er others, and suggest many unnecessary and impossible things. ControJ of expectoyat'ion. At one time more importance was attached to the spread of tul)erculosis 1)y the inhalati(ni of the dust of the streets and public places than is at the present time. As a result of the view that tuberculosis is chiefly spread in this way, various ordinances have been adopted to ])revent indiscriminate expectoration. The first rule of this kind was that adopted by the Board of Health of New York City, May 12, 1896. By this rule it was forl)idden to spit upon the floor of the public buildings, of railroad cars and ferry-boats. Rules covering this sujjject have since been adopted l)y a large numl)er of cities and towns and by the State Board of Health of Indiana, but have not yet been incor- porated into statute laws. Many of the rules go much further than that of New York, and forbid spitting in omnibusses, hacks, carriages, vehicles, steam-cars, or any pul)lic conveyance, also in public halls, 'assembly OF TUBERCULOSIS. li rooms, shops, stores, halls, i-ailway stations, churciies, sehoolhouses, and other })Lil)lie places. Some of the rules go further still, and forhid the spitting upon the sidewalk, as in Cincinnati, Cambridge, Colorado Springs, l^rookline. Providence, Springfield, and Rochester. The following is the rule in Cambridge, and perhaps is as explicit as any : Cambridoe ; Rules of the Board of Health, April 12, 1S99 : The Board of Health hereby adjudoes that spitting upon the floor, platform, or any other part of a public conveyance ; upon the floor, steps, or stairs of any public building, hall, church, rail- way station, or sho]> : upon the sidewalk of any street, court or passageway; or ui)on the patlnvay of any park, square, or com- mon is a nuisance, source of Hlth and cause of sickness, and pro- hibits spitting in any and all such places. Many of the rules require tliat copies of the rule shall be conspicuously hung in public conveyances and other public places. Most of the transportation com- panies are very ready to do this, and have welcomed the law, and have tried to enforce it. Cases have Ijeen brought for violation of these rules, and it is said that the courts have sustained them. It requires a good deal of effort, however, on the part of the police, to secure any permanency in this reform. It is, perhaps, questionable whether rules of this kind can be enac^ted as necessary for the preservation of ])ublic health, but, fortunately, it is not necessary to prove the exact i-(jle played by promiscuous spitting in the production of tuberculosis to enact such legislation. Promiscuous spitting is a nuisance and may be sup- pressed on that score alone, thus enabling us to try a very practical experiment as to the importance of one alleged means of spreading tuberculosis. 28 THE STATE CONTROL The surest way to prevent expectoration in ])laces where it may be dangerous is to keep consumptives out of such phices. It is dou))tless for this reason that Pennsylvania has passed a hiw forbidding tlie employ- ment ])y bakers of persons having consumption, and the sanitary code of Yonkers makes it a misdemeanor for leakers or market-men to pursue their occupation if they have this disease. Very little lias Ijeen done Ijy any municipality to control expectoration by regulating the conduct of the individual. In New York City, wdien a case of con- sumption is reported to the board of health, unless the attendant physician recjuests otherwise, an inspector is sent to the home of the patient and gives verljal direc- tions how to dispose of tlie sputum without danger to others. Subsequent visits are made to see that these directions are carried out, and it is claimed that they are in about one-half of the cases. Doubtless, all over the land, educated physicians in private practice and in charge of institutions, have done much to teach patients in regard to this matter, and prol)a])ly have accomplished far more than have the health officials. Disinfection. Experiments have shown that it is ([uite possible that the apartment occupied by a consumptive patient may become infected with the germs of the disease. Scrapings have Ijeen taken from the Avails and furni- ture of such apartments, and have Ijeen found to contain bacilli. There is not, however, much clinical eA'idence that such apartments may be the cause of spreading the disease. The investigations of Flick, in Philadelphia, and of the board of health in New York OF TUBERCULOSIS. 29 City, show that certain houses appear to be the homes of tuberculosis. Certain houses have had cases in them for a long series of years. A minority of the houses furnish a majority of the cases. There are few cases on record, however, where a tubercular family has removed from a house and a non-tubercular family entered it and Jjecome infected. A case of this kind has recently been reported in the Indletin of the Ohio State Board of Health. But such cases are not more numerous than could reasonably he explained as coin- cidences. Still, it nnist be admitted that there is some chance of the disease Ijeing spread in this manner, so that it is advisable to disinfect premises that have been occupied by consumptives before they are occupied by others. This is commonly done by municipal boards of health, when requested ))y the family, and such requests are becoming quite common. Doubtless, alsO, many per- sons thoroughly cleanse the premises, practically disin- fecting them, without calling upon the health otiicers. A few cities, notably New York, require the disinfec- tion of such premises ; but the method prescribed is cleansing, rathei- than disinfection. It is required that all walls and woodwork shall be washed with washing soda, one-half pound to a pailful of hot water, and then the room is repapered, whitewashed or kalsomined. Occasionally goods are taken away and steamed. HospltaU. It is considered that isolation hospitals are a neces- sity for the control of communicable diseases. If they are needed in scarlet fever, diphtheria and small-pox, thev are needed still more in tuberculosis. Jn tuber- 30 THE .STATE CONTROL ciilosis, far more than in any otlior disease, does the welfare of the })atient depend npon hospital treatment. By going to a hospital, not only does a patient avoid all danger of giving the disease to others, but he stands a nnich Ijetter chance of getting well. There are not many hospitals for consimiptives in the United States, and some of these are designed more as homes of refuge for the inciu-al)le poor than as true sanatoria. In Germany the use of hospitals for the cure of con- sumptives has been known for a long time. There are many such hospitals, and many patients are cured in them. Knopf says that cures can be obtained in from 25 to 50 per cent, of the ca^es. Of 5,032 patients at Goerbersdorf, in Germany, from 1876 to 1886, 11 per cent, were reported as cured, and 15 per cent, as almost cured. Of 1,390 received during the first stage of the disease, 27 per cent, were cured, and 31 per cent, almost cured. The other German sanatoria report cures of from 14 to 27 })er cent. Several French sanatoria report cures of from 21 to 50 per cent. The Loomis sanitarium in New York reports 25 per cent, of cures and 50 per cent, of ameliorations. The Saranac sanitarium reports 20 to 25 per cent, of cures. At Chestnut Hill, Philadelphia, where patients in all stages are received, there are 8 per cent, of cures and 11 per cent, of ameliorations. Perhaps the most striking proof of the ^-alue of hospital treatment is shown hy the action of the st?ite-aided insurance companies of Germany. These companies Hnd it for their advan- tage to send their policy holders who become phthisi- cal, to sanatoria, and to pay their board while there. During 1898, Ijetween three and four million marks were expended for that purpose. It has Ijeen shown OF TrCERCULOSIS. 31 that it is not necessary to go into deejj forests or high mountain regions to secure a good location for a con- sumptive hospital. Dry and somewhat isolated situa- tions can be found, suital)le for these hospitals, within a few hours' journey of nearly all our cities. Consid- erable difticulty has. at times. l)een found in seeming a site for such hospitals, the people of the locality tear- ing: it mav be the means of introducino- contao-ion. This fear is unfounded. The care which is exercised in hospitals to prevent the spread of contagion is etfectual. It is shown that at Goerbersdorf and Fal- kenstein, the death rate from phthisis has diminished from 18 to 11 per cent, since the sanitoria were estab- lished. Hospitals not only help to cure a patient and keep him from infecting others, but they teach him habits of care in regard to the disposal of spntmn, and in •other ways instruct him in the principles of hygiene, so that when he leaves the hospital he is much more likely than liefore to lead a healthful life and to avoid infecting others. The cost of treatment in hospitals designed for the care of consumptives is not far from the cost in gen- eral hospitals. The cost in the German hospitals is 6(1 to 80 cents per day; the cost in St. Joseph's Hospital, New York Ci^y, is 50 cents ; and of the Chestnut Hill Hospital in Phihxdelphia, 40 cents. These hospitals, however, do not offer the best facilities. The cost at Saranac Lake is from $1 to |1.2o ; at the Loomis San- itarium, $1.43 ; at the Cincinnati Hospital, about .$1.25. The exact figures for the hospital in Massa- chusetts are not given, but are apparently considerably greater. Knopf says it is more economical for the 32 THE STATE CONTROL municipality to care for its phthisical poor in special sanitaria than it is in general hospitals. The initial cost may be somewhat greater, but the length of stay is pretty certain to 1)e less, and, in the aggregate, many years of useful life will be preserved to the community. Considering tlie advantages wliich are secured hy hospital treatment, it is rather remarkaljle that in this country so little has been done l)y the state to furnish it. The first and only municipal liospital for the care of consumption, with which the writer is ac([uainted, was that at Cincinnati. This is a substantial brick Ijuilding in the suburbs, jjuilt for a, smallpox hospital, but devoted to the care of consumptives since July 8, 1897. The hospital and other buildings, exclusive of land, cost about |rSO,000. During the first two years that the building was occuj)ied, 330 patients were treated. The visiting physician. Doctor Lyle, reports some cures and many improvements, but he has not been able to follow the cases very carefully after their discharge. This hos- pital, however, is not intended so much as a curatixe institution as an isolation hospital to which patients may go instead of entering the general hospitals of the city. Massachusetts has set the example for the establish- ment of State hospitals. The Massachusetts Hospital is at Rutland, in that State, and was opened for the reception of patients on Oct. 1, 1898. It is intended to accommodate 200 patients, and cost over $150,000. It is intended for patients in the early stages of the disease. There is a uniform charge made of 50 cents per day, but poor patients may l)e admitted without OF TUBERCULOSIS. 33 charge on application of the poor department of the town to which they belong. Of conrse, this board does not begin to pay the running expenses, and these are met by State appropriation. Control of Milk Supply. It is, of course, useless to attempt to secure a milk supply which shall be free from tuberculous taint, except by inspection and control of the dairies from which the milk is derived. As yet, not very much has been done along this line, in the United States. In New Jersey and Wisconsin the laws permit of the inspection and licensing of dairies. In Minnesota a somewhat recent law confers upon cities the authority to license milk producers, and inspect and test dairy cows. This law has been tested and its validity upheld by the Supreme Court. Notwithstanding the dearth of specific legislative authority, a considerable number of cities have taken more or less enero-etic o action, looking to the supervision of the sources of their milk supply. In some, the action taken is merely one of inspection, advice and publicity ; in others, control is exercised over dairies within tlie jurisdiction of the municipality. In others, the at- tempt is made to control all the sources of milk supply of the city.^ It is necessary, first, to obtain a knowledge of all the dairy cattle supj^lying the city. To accomplish this, every dealer must be licensed and must keep the authorities informed of the location of every herd from which he obtains milk. This method is followed in New York, Minneapolis, St. Paul, the District of 34 THE STATE CONTROL Columbia, St. Louis, Buftalo, Lynn, Nashua, Portland, and other cities. The second step is to provide for an inspection of the herds and dairies from which the milk is derived. Sometimes this inspection is confined to the limits of the city, as it is in New York, Baltimore, Cincinnati, and the District of Columbia. Of course, such local inspection cannot accomplish much. Every herd sup- plying the city should ])e controlled. Among cities which have attempted to inspect every herd supplying the city may be mentioned Portland, Lynn, Nashua? Rochester, the District of Columbia, Minneapolis, St. Paul, St. Louis and San Francisco. Lastly, it is necessary to test with tuljerculin ever}^ animal from which the municipal supply is derived. By licensing dealers, by registering jDroducers, by in- specting their herds, by testing the cattle witli tuber- culin, and condemning all infected animals, hy tagging the animals so that they may be identified, and by re- inspecting, at intervals, the milk supply may be kept free from tuberculosis. This method has, at present, been successfully adopted only in Portland and Westr brook, Me. ; in Lynn, in Minneapolis, and St. Paul. Such drastic methods are sure to meet with great opposition, and permissive legislation is difficult to obtain. The attempt was made in the District of Col- umbia, and San Francisco, but Avas a failure. In Massachusetts, also, the authority was sought by which local boards of health could, in this manner, control the milk supply, but it was successfully of)posed by the milk dealers and producers. The attempt has been made in New Orleans, St. Paul, Indianapolis, and, doubtless, in other cities, to improve the milk sup]3ly by moral agencies. The OF TUBERCULOSIS. 35 municipal authorities offered to test tlie dairyman's herd and certify to those which were found healthy. Few, howeyer, took adyantage of the offer, for they did not find that the expense and trouble were com- pensated by increased custom. This method, howeyer, was successful in Indianapolis, where nearly all the dairymen liaye yoluntarily sul)jected their animals to inspection. In 8t. Paul, on the other hand, the city was obliged to resort to compulsory methods. The limited demand for "certified milk" shows that the public is hardly ready to ask for clean milk, or willing to i^ay for it. The Eradication of Tuherculosis in Cattle. If it is true, as is not improbable and as many would haye us belieye, that a large part, perhaps eyen half, of human tuberculosis is deriyed from cattle, an impor- tant step in controlling the disease in man is to get rid of it in animals. It may. perhaps, be admitted that the eyidence is not strong enough to warrant our taking the radical ste'ps necessary to get rid of tuber- culosis, on account of its danger to human beings. ])ut there are other and ample reasons why the State ^should seek to free its herds from tuberculosis, as it has from pleuro-pneumonia and other infectious dis- eases. In/this work, howeyer, the co-operation of the dairyman and farmer cannot be expected, as it maybe in the acute diseases. Tuberculosis is a chronic aft'ec- tion. The cattle owner can detect it long before death, make use of the milk for a considerable period of time, and finally sell the animal for slaughter, at a small loss, or perhaps no loss at all. The trouble and ■expense incurred in entirely freeing a herd from 36 THE STATE CONTROL tuberculosis are considerable, and the average man who hesitates to incur a momentary loss for the sake of future gain, had rather take the chances of losing a little money now and then on a cow, than of going to the trouble of getting rid of the disease altogether. Nevertheless, the aggregate loss from tuberculosis is enormous, and the State would be justified in making large expenditures to exterminate it. Various plans have been suggested and tried for getting rid of tuberculosis in cattle. The most radical measures were those adopted in Massachusetts, where the plan was adopted of inspecting every animal in the State, and killing and destroying all which reacted with tulierculiu. Large sums of money were ex- pended, great opposition was aroused, and the plan had to be abandoned. A somewhat similar, but less rigorous method, was adopted in Belgium, in 1896, but it also has been modified. In Baden, herds from which tuberculous cattle are reported by the meat inspectors are examined and measures taken for the suppression of the disease at the expense of the state. In Baden, as in Saxony and other parts of Germany, a part of tuberculous meat is used as food. In France, also, the flesh of tuberculous animals is not always condemned, though animals that are discovered to be tuberculous are always killed. In Denmark, the state offers to test herds for their owners, and tuberculous cattle are killed if the disease is far advanced, and their flesh is then destroyed. In the early stages of the disease the animals may be kept in quarantine, or they may be slaughtered and are largely used for food ; Ijut the milk and cream of quarantined animals cannot be used without pasteurization. A similar plan has been adopted in Norway. OF TUBEECULOSIS. 37 It is of specital interest to us to know what is Ijeing done in the United States. The importation of tuljerculons cattle into the United States is guarded against by the inspectors of the Bureau of Animal Industry. While this bureau might under the laws attempt to prevent the passage of tuberculosis from one state to another, it has not yet had the means for doing so. This is at. present controlled by the states, and eighteen of them have laws respecting it, among which are Maine, New Hampshire. Vermont, Massachusetts, Rhode Island, New Jersey, Pennsylvania, Iowa, Montana, and Texas. A common form of the law is that requiring that no animal shall l)e imported without a certificate that it has been inspected and tested with negative results. In Texas cattle must not be imported for breeding or dairy purposes, and an exception is made in favor of animals certified to as natives of Colorado or Ne- Ijraska. In New Hampshire animals may be brought in for pasturage only, without the tuberculin test, provided they are sound on physical examination. In Connecticut, when any one imports cattle from an adjoining State he must, within six days, notify the commissioner on domestic animals. Very little work has l^een done in eradicating l^ovine tuberculosis Ijy municipal health officers except in connection with the protection of the milk supply. Nearly all the active work, except in a few cities as New York. Minneapolis, St. Paul, Indianapolis, Roch- ester and Lynn, has been done by state boards. Some of this work is done by l^oards of cattle commissioners and some by state boards of health. Much of the following summary is taken from the seventh annual report of the state veterinarian of Maryland. 38 THE STATE CONTROL 3IassachHsetts. Under Chapter 491, acts of 1894, some 465 inspectors were apjDointed, whose duty it was to inspect cattle and stables, and report the occur- rence of any contagious disease. All cattle visibly affected with tuberculosis were killed and paid for, while many w^ere tested at State exj)ense at a cost of $240,737.84. This does not include the cost of test- ing many more cattle, which was made at the expense of individual owners. Condemned cattle were paid for upon written applica- tion for the test to be applied, and upon the provision to thoroughly disinfect their premises, and to introduce none but cattle tested (at owner's expense) in future. This led to an order that cattle to be paid for must be tested Ijy the cattle commissioners or their authorized agent. The large amount of money spent and the numl:>er of animals destroyed caused great opposition and resulted in a change of policy. It is now ref[uired by law that each town and city shall appoint an in- spector who will act in conjunction with the state board. This work may be considered under three heads : 1. The supervision of the traffic in live cattle brought into the State. 2. A general inspection, the examination of cattle quarantined as diseased by the local inspectors in the various cities and towns, and the payment for those found to be infected with tuberculosis. 3. Testing entire herds for the purpose of perma- nently eradicating tuberculosis from the premises. In 1899, $75,000 was appropriated and only|50,000 was to be asked for the next }' ear ; 785 tuberculous animals were killed, for which $17,277.69 was paid ; 565 animals were tested for owners who Avere trying to free their herds, and of these 63 were condemned. OF TUBERCULOSIS. 39 Maine. Maine was the first of the New England States to adopt the system of placing quarantine on the admission of out-of-state cattle. The law was first enforced in 1802 against Massachusetts, because of the large per cent of Massachusetts cattle that were found diseased. Later it was placed on all out-of-state territory, except on such animals as were provided with certificates of the tuberculin test. The authori- ties in Maine test lierds only on the voluntary applica- tion of the owner. The owner to receive one-half the value, as determined on the basis of health before infection, the limit of compensation being $100 for pedigreed animals and |50 for others. The commis- sion have power to investigate as to the existence of disease and to condemn and destroy such as show physical evidence of disease. During the year 1898, 415 head of -cattle were destroyed at an appraisal of $18,122. Vermont. Vermont, with its small percentage of diseased animals, has probably been more successful than any other State in its attempts to control tuber- culosis. Since Feb. 1, 1897, 60,000 have been tested, and 2,360 have been found diseased and killed, a percentage of disease of nearly four per cent. In Vermont i^o animals are tested unless the owners allow the entire herd to be tested, and thereafter every animal admitted to the herd must be tested and the stables thoroughly disinfected. The commission test only where application is made by the owner. In their annual report a list of seventy-eight retested herds is given, in which tuberculous animals were found. Twenty-three herds were found free on the second test, and twenty-three had only one case each on the second test. Eight of the remaining herds that 40 THE STATE COXTHOL were found diseased on the second test were free on the tliird test. The report states that " the proper dis- infection is a more diffienlt matter tlian is the discovery of the diseased animal."' The commissioners have found that cattle Ijuyers from States where no ({narantine was enforced have purchased many suspected animals at a price a little less than would have been paid if not suspected. New Hampshire. Diseased animals are reported to the commission through the selectmen, and are released or condemned on physical examination. When the owner applies for inspection of his herd, and where there is reason to believe the disease exists, the board may treat the entire herd, the owner receiv- ing half compensation. In 1808,225 herds were tested and 148 animals killed for which $2,894 was paid. Hhode Island. Rhode Island has a commissioner in each county, appointed by the l)oard of agriculture, whose duty it is to inquire into the condition of any animal in their county whenever there is any reason to suspect tuberculosis. When any animal is thought to be tuberculous by a commissioner, he shall immediatel}^ quarantine and examine. In 1 898, 49G animals were killed for which $9,014.50 was paid. JVeiD Yorli. In New York state, tuberculosis in cat- tle is handled l)y a tuberculosis committee of the state board of health. No appropriation has been made by the legislature for the use of this committee and no cattle have been ordered killed, except where the owners have waived all right to compensation. The commit- tee, however, have received many requests from owners asking to have their herds tested ; and also test the animals belonging to public institutions. OF TUBERCULOSIS. 41 JVew Jersey. New Jersey lias a commission of seven members. The commission, on application from the owner, the state board of health or the state dairv com- mission, will make an examinatien of suspected herds, the reacting animals to be condemned and killed. They are appraised at their market value, not exceed- ing forty dollars, the owner receiving compensation at the rate of three-fourths of their valuation. In 1898 there were tested 1,438 cows, of which 245 were con- demned. The cost of inspection was $1,179, and the amount paid for the cows was $5,098.20. Pennsylvania. It has been the practice in Pennsyl- vania to test herds only on the application of the owner, and then only where the disease was suspected to exist. The application is made on a printed form, and in mak- ing the application the owner promises to observe every direction recommended that tends to the purification of his premises. If he has to tear down half his Ijarn, or cut windows through his stables, or put in new floors, he agrees to do that before the examination is made, and he agrees also to procure his animals for restocking from as healthy a source as possible. It has been impossil)le, however, to comply with all the recjuests sent in, and. as far as possible, the worst herds have been picked out for testing. Reacting animals are all condemned and compensation given the owner. At the time of pul^lication of the last annual report the average appraisement for cattle condemned was twenty-four dollars and fifty cents. Since the begin- ning of the last fiscal year the total payments for tuljer- culous cattle to date (January 1, 1898,) amount to $57,191.16 for 2,510 animals, an average of $22.78 per head. 42 THE STATE CONTROL In Pennsylvania the number of cattle tested up to the 1st of June, 1897, was 0,108 ; the number con- demned as tuberculous was 1,839, a percentage of 20.39. Since the 1st of June, 4,887 cattle have been tested ; of these 671 were found to be tuberculous and were killed ; a percentage of 13.73. All parts of the state are represented among these herds, as only herds sus- pected as diseased are tested. The state officials be- lieve that many of the w^orst herds have been discov- ered, and that the percentage of tuberculosis among cattle at large is being steadily and rapidly re- duced. lU'mois. The live stock commission has been con- ducting tests on herds where the OAvners appl}^ for it. All animals are slaughtered w^ithout compensation, the owners having whatever there may be from the sale of the hide and carcass ; where the disease is slight the beef may be sold, if fit, for food. During the year 1897, 36 herds were tested, includ- ing 851 animals; of these 77 were found diseased, or about 9 per cent. (This percentage includes a herd of 251 that had previously been tested.) Of the 77 dis- eased animals, 41 carcasses were condemned and 36 passed as fit for food. During the year the board has made tuberculin tests on all dairy herds for which applications w^ere made. There were fewer tests made in 1898 than during the previous year, not because the disease was any less prevalent among the untested herds of the state, but simply because a less number of owners of herds ap- peared to be willing to bear all the loss to be sustained thi'ough the members of their herds that would respond to the test. OF TUBERCULOSIS. 43 Mlchifjan. Cattle found to be tuberciiloiis are quar- antined and killed. The laAvdoes not provide compen- sation, however, and, as a result, the commission has met with a good deal of opposition. The commission has followed the plan of inspecting animals brought to their attention as suspicious, and killing such as reacts without compensation. During 181J7 and 1808 the commission has applied the tul)erculin test to nearly 1,000 head of cattle, a goodly proportion being milch cows. In fact, a larger number of cattle have been tested for tuberculosis dur- ing the last two years than had previously been tested since the tuljerculin test was adopted by the commis- sion. The tuberculin test is apphed only when suspicion is directed toward, or complaint made of, either a single animal or an entire herd. The records of tests made show but a small per cent, of infected animals, and when it is considered that only suspicious herds are tested, it is felt to be a- safe estimate that less than two per cent, of the cattle in Michigan are affected with tuberculosis. Minnesota. All cattle which show symptoms of tuberculosis must be quarantined at once and the entire herd tested with tuberculin. When cattle have once reacted the owner has his option of having them killed or continued in quarantine for a j^eriod not to exceed three months, when they are again tested. If they react on the second test, they must be killed within one month. The owner has no compensation for cattle killed, but he is allowed to have them killed under inspection, and, if they pass, he can dispose of the flesh like any other beef. In 1898, 2,975 cows mostly 44 THE STATE CONTROL fui'uisliiiig milk to St. Paul were tested and G.37 per cent, were condemned. Wiscoitsij/. The state l)oard of health are applying the tubercidin test to infected herds reported, as far as their means Avill allow and condemning the animals that react to the test, the state paying two-thirds of the appraised value. It has not seemed necessary in this discussion to con- sider the value of the tuberculin test any more than the causative relation of the tuljercle bacillus to the disease. All competent persons seem agreed that in tuberculin we have the Ijest means possijjle for making a diagnosis of this disease. It is not infallible, hut per- mits a very much surer diagnosis than can be obtained by any other means. Without it, the eradication of tuberculosis would be much more difficult and expen- sive than with it. With tuberculin the recognition of the disease is the most certain part of the work. Perhaps the most diffi- cult part is the disinfection of infected premises. The following directions which the Massachusetts Board of Cattle Commissioners insist on being carried out on all premises that they attempt to free from the disease are perhaps as good as any : REGULATIONS OF MASSACHUSETTS liOARD OF CATTLE COMMISSIONERS FOR CLEANSING AND DISINFECTING BARNS. lliese Must he (.'oiiqilied With by Ov:ners of Cattle, U'/ilrh the State Payn For. In attempting to get rid of tuberculosis in a herd of cattle, it should be remembered that not oul}" is it necessary that all the diseased animals be picked out and either isolated or destroyed- OF TUBERCULOSIS. 45 but that no new animals should be introduced unless they have been tested and are known to be free from disease. The barns should also imdergo a thorough renovation and be properly cleansed and disinfected before they are again occupied. In renovating or remodelling barns the great imjiortance of sunlight, thorough ventilation and good drainage should always be borne in mind. Disinfection of the barns is always necessary to destroy any infectious material that may have been left after the removal of diseased cattle. The best disinfectant we know is sunlight. Germs of disease will live but a short time when exposed to the direct rays of the sun, and for this reason, if for no other, a southerly exposure and plenty of windows in the barn are to be desired. In proceeding to disinfect a barn the first, and perhaps the most important step to be taken is to collect all rubbish, have the walls, ceilings and floors thoroughly swept and cleansed of all litter, dust, cobwebs, and the like. The floors, mangers, feeding- troughs and stanchions should be carefully scraped and cleaned, special care being taken with the corners, and all of the rubbish xjollected and burnsd. All odds and ends of boards and old and broken mangers and partitions should also be removed and burned, and when occa- sion requires it, new plank floors should be laid in place of old ones. After cleaning thoroughlj^ with hoe and broom, and hose if running Avater is convenient, and if the barn contains a boiler Avith scalding water, or live steam, applied with a hose, or failing that, with boiling water and soft soap or Avashing soda. A solution of bichloride of mercury (corrosive sublimate), 1 to 1,000 parts of Avater, should be applied Avith a AvhiteAvash brush and poured over the floors. (CorrosiA-e sublimate should be used in Avooden ves- sels, as it corrodes metal ones.) After applying the corrosive sublimate, the ceilings, Avails, par- titions, mangers, etc., should again be washed and gone over Avith warm freshly made white Avash ; a half pound of chloride of lime to the gallon of AvhiteAvash is an addition that may make it more effective. Fumigating with sulphur or chlorine gas is not of any great value in ordinary stables. 46 THE STATE CONTROL In using corrosive sublimate it must he borne in mind that it is a dangerous poison, and mangers and partitions should be care- fully Avashed after applj'ing this mixture, and then again scalded or whitewashed. If at a season of the year when the animals can be turned out, the stables should l)e left vacant for some time with doors and windows open. Six months after the first test the herd should again be tested and undergo a careful physical examination, so as to be certain that no diseased animals have been overlooked, and the barns should again be thoroughly disinfected. Great care also should be taken that all animals have been tested before their introduction to the herd. THE DECREASE OF TUBERCULOSIS. Over most parts of Western Europe, Great Britain and the United States, there has, for half a centiuy, been a marked decrease in the number of deaths due to tubercuhxr diseases, and particuhxrly in deaths from consumption. The figures, of coin^se, vary somewhat in different localities, but the fact of marked decline is illustrated by almost all registration rejDorts which cover a considerable number of years. It seems liardlj^ necessary to present a mass of statistics to demonstrate this, but it may not be uninteresting to examine the data from local sources which are herewith presented. The followino; table is from the advance sheets of the report on births, marriages and deaths in Providence, for 1899. The main fact of the decline is shown graphically in the succeeding diagram : OF TUBERCULOSIS. 47 Decedents from Phthisis, Forty-four Years, 1856-1899. Parentage. Sex. 1 S American. Foreign. Males. Females. ft YEARS. to 5 OS c ai 5| 1 IS . ftp 1 = 1 ftp 1° O § a o 1 1856-60 1861-65 1866-70 1871-75 1876-80 1881-85 1886-90 1891-95 1896 1897 1898 1899 525 495 532 553 570 573 '62^ 486 91 92 87 99 364 329 306 252 235 227 204 no 153 151 135 149 236 405 480 520 682 928 1,177 1,206 1,202 259 229 238 268 391 i 420 384 332 322 371 329 286 285 246 243 264 326 379 477 490 668 676 824 863 846 180 178 178 177 324 387 339 279 267 304 288 253 249 233 228 219 551 498 562 667 822 926 872 842 170 148 147 190 421 352 342 301 301 310 266 233 218 185 174 218 285 930 975 1,052 1,235 1,498 1,750 1,735 1,688 350 321 325 367 1 375 368 340 290 285 307 277 243 233 ; 208 ; 200 218 44 years 4,632 1 / 7,594 5,831 285 6,395 1 12, 226 j 285 48 THE STATE CONTEOL Pkovidknce, R. I. PHTHISIS. Deaths pkh 100,000 Living. 18.55-1804 380 180.5-1874 317 187.5-1884 298 188.5-1894 259 1895-1897 212 It lias been claimed by many that this diminution in the death rate of phthisis is, to a large extent, due to the application of the knowledge recently acquired. The writer, however, does not believe that this is the case. Certainly, in most places, as has been shown, very little has as yet been accomplished in regard to the purification of milk supplies or the eradication of bovine disease. Expectoration laws are not enforced, and no more consumptives are cared for in hospitals than formerly. It is true that some few cases do, OF TUBERCHTLOSIS. 49 undouhtedly, take rational measures to prevent infect- ing- others. Physicians have been a)jle to teach a minority of their patients to do this. It can scarcely be believed that such very little progress has produced such marked results. The decrease in consumption in the United States has not jjeen due to state control, for the excellent reason that the state, as yet, has not Ijeen able to excercise any efficient control. The only city where anything of consequence has been done to check the spread of tuberculosis from man to man is New York. An inspection of the death rate from phthisis in that city does not show that it has decreased any more rapidly since 1895 than it did before. It is not necessary in this paper to attempt to explain why consumption of late years has diminished to a cer- tain extent, but it is generally believed to be due to improved living on the part of our people. Better food, better clothing, better shelter and better care of the sick have done much to improve the general health. Shorter hours for work and more time spent in the open air, especially by women, are supposed to be ele- ments in causing the decrease. METHODS OF CONTROL PROPOSED. Notification. The writer believes that one of the most important things to be done to control tuberculosis is to study still further the manner in which the disease is caused. Experimental evidence is desired on many points, as has been referred to in the preceding pages. Clinical evidence is still more to be desired, and this can be best obtained by government investigation. It is neces- sary to study a very large number of cases etiologically. 4 50 'rilK STATE CONTKOl^ If for no other purpose than to give an ()])portnnity for such Htudy, the wtate should recpiire the report of all cases of tuhercnlosis. It is just as important to study other varieties of tuberculosis as it is to study ])hthisis. They should all he reported as is recjuired in a number of existing regulations. There has been considerable opposition to the notification of this disease, but it is believed that this has been due largely to a fear that the health officer would interfere with the family phy- sician by the advice which he miglit give to the patient. If the health officer does not so interfere, but merely co-operates with the physician, it is believed that it will not l)e any more difficult to secure reports of tuber- culosis than it is of scarlet fever. It should be the duty of the health officer to study with the help of the attending physician the causation of every case re- ported. Notification presupposes correct diagnosis, and therefore every state and city should certainly offer facilities for tlie examination of suspected sputum. Education. Every sanitary official should do all that he can in every way to spread abroad a correct knowledge of the causation of this as of all other communicaljle diseases. The daily press usually affords valuable assistance in this. Another and most useful means of educating people is by means of circulars. Every local health officer shoidd provide himself with a circular explaining the means by which tuberculosis is spread, and describ- ing what precautions should be taken to prevent its spread from one person to another. Such a circular should be prepared with very great care. It should be OF TIBEIICULOSIS. 51 expressed in language wliicli can be readily under- stood, and it is very important that it should contain no statements which cannot be fully substantiated. Impossible things should not be required. It is advis- able to send such a circular to every family in the community, stating upon it that this is done. By so doing, no one can be offended. It is, of course, very desirable that it should be made certain that the family of every consumptive should receive a copy, and where there is a physician in attendance, the circulars may well be presented by him. The following is offered as a form of circular for general distribution : Consumption, or tuberculosis of the lungs, is caused by the bacillus of tuberculosis, a kind of germ or microbe. This germ also sometimes causes consumption of the bowels especially in children, and sometimes it causes disease of the bones or of other parts of the body. All these different kinds of tuberculosis are caused by the germs getting into the body in one way or another. Persons who have consumption usually have a cough, and the matter that they cough up contains great numbers of the tiny germs which cause the disease. If the sputum or matter coughed up gets on the carpet, floor, furniture or clothing, it may become dry and powdered, and float about in the air. It may then be breathed in by another person and thus start another case of the disease. In cases of consumption the face and hands are likely to become soiled with this sputum, and cups, spoons, forks, pencils, handker- chiefs and othfer things are likely to be infected in the same way.' If other persons use these things before they are thoroughly washed they are likely to catch the disease. In cases of consumption germs are not given off by ordinary breathing, though in coughing or sneezing they may be. But there is probably not much danger from this except to a person who remains much in close contact with the patient. A person who has consumption should always sleep alone. Cows have tuberculosis as frequently as human beings do. When they have it the milk is likely to contain the germs of the 52 'I'lIK STATE (CONTROL disease, and ])ers()iis wlio drink tlie milk are likely to have tuber- culosis. No milkman ought to keep a tuberculous cow in his herd. He ought to have his cows examined every year and kill all that are sick. It is a good }>lan for all persons to iiKjuire of their milkmen as to whether their cows have been tested for tuber- culosis. It is the duty of every ]»erson who has consumption to take the greatest care of his sputum, for it is this that is particularly dangerous to others. AVhen at home he should always spit in a cup which should contain water, so that the matter may not dry. This cup should be emptied into the water closet at least twice each day and be thoroughly washed in boiling water. Paper spit cups may l)e used which can l»e burned. These are furnished by the health department to those unable to pay for them. When away from home a person who has this disease should sjiit into a pocket flask which should be emptied into the water closet and scalded on returning home. These flasks are furnished by the health dei)artment. A person with consumption should never spit anywhere except into a spit cup or flask. He should take great pains not to get sputum on his hands or clothes. Hand- kerchiefs used to wipe the lips and nose may be carried in a rub- ber-lined pocket so arranged that the lining can be removed and washed. Handkerchiefs should be washed frequently. As the face and hands of the patient are certain to be more or less infected they should be frequently washed in hot water and soap. It is best for a mail with consumption not to wear either mustache or beard. All dishes used by a consumptive should be thoroughly scalded before they are used by another. The bed clothes and night clothes of a person with consumption should be changed often. AVhile consumption is contagious the contagion is almost entirely in the sputum, and if this is taken care of there is prob- ably not much danger in living or woi-king with a consumptive. Consumption is not always a fatal disease. A great many per- sons who have the disease recover from it. A large proportion of cases get well if they take proper care of themselves. When a person with consumption has been sick a long time in one room, even if great care has been taken, the woodwork and OF TUBEKCT'LOSItS, 00 furniture are liable to be infected and should be tborougbly washed. It is a good jilan to use Avashing soda for this. The walls should be repapered, the old paper being taken off. Car- pets and rugs should be disinfected with steam. Conti'ol of Ex2)ectoration. As has been said, indiscriminate spitting is a nuis- ance and should Ije stopped. Spitting in pul)Uc places should, bj statute law, Ije made an offence. In place of statute law, if such cannot be obtained, every muni- cipality should have a regulation of this kind and enforce it. It is not at all improbable that such en- forcement mig-ht have considerable influence in check- ing the spread of consumption. It is perhaps possible for the health officer to do much in the way of helping the individual to care for his expectoration. The plan followed in New York city of visiting the patient, unless the attending physi- cian requests otherwise, appears to be a good one ; and, in that city, has been productive of good results. Subsequent visits shauld, however, be made, and if the inspector has tact and gains the confidence of the patient, much may be accomplished. When in the house, it is probable that the best thing for a patient to do is to use a spit-cup. These are made in various forms and one made by Seabury & Johnson, which has a paper lining which can be removed, and, with its con- tents, burned, is a very good one. If a person is able to be about, and, particularly if he is alile to work, he must be j)rovided with a pocket flask and perhaps, also, with some sputum receptacle at his place of busi- ness. A pocket flask made of aluminum in two pieces, so that it can be readily taken apart and cleaned, has been devised by Knopf and is probably the best that 54 THE STATE CONTliOE can be obtained. If snch a flask is not employed, handkerchiefs may be used, Ijut, if tliey are, the pocket which hohls them shonhl have a rubber lining kept in place by clamps. Cups, flasks and rubber lining should all be frequently washed and scalded, and disinfected if feasible. If the consimiptive can l)e induced to thus take care of his expectoration, the danger of his trans- mitting the disease to others will be reduced to a min- inuuii. The health inspector, either by himself or with the assistance of the attending physician, can doubtless do very much to bring about this desired end, but it is not, by any means, recommended that any compulsion should be employed. It might he advisable for the municipality to furnish the spit cups and flasks to those who cannot afford them. Dismfection. Every municipality shoidd be ready to show how apartments can be disinfected after cases of consump- tion have been removed from them, and should stand ready to disinfect if it is probable that it will not other- wise be properly done. It might, perhaps, be advisable to require Ijy ordinance that all premises occupied by consumptives should Ije disinfected before they are occupied ]jy others. There seems to be little doubt that cleansing, as practiced l)y the board of health in New York, is as good as disinfection. Disinfection, if practiced, should always be hy washing, and steaming, if necessary ; gaseous disinfection should not be relied upon. Hosjntals. There is no question in the mind of the writer that hospitals furnish the Ijest means availaljle for the state OF TUBERCULOSIS. 55 control of tuberculosis. The majority of consum})tive patients are among the poor or people in very moderate circumstances. It is extremely difficult for such to take the precautions necessary to prevent the spread of the disease ; therefore the danger is greatest from this class of persons. Unless something is done to help them, they are almost certain to die. If they can be cared for in suitable sanatoria, a large proportion will recover, provided they, are taken in hand early enough in the disease. Furthermore, during the whole time of their treatment, there will be no danger of their infecting others. The state should provide hospitals for the curative treatment of consumption in its early stages. The consumptive poor who are suffering from the last stages of the disease should also be cared for by the state. Although the danger to be apprehended from this class is not great, because they do not move about so freely, and although the chance of cure is slight, humanity demands that they should receive the best of care. General hospitals very properly do not like to receive them, but they are frequently obliged to, to the danger of other patients. The state should also receive them, as well as incipient cases, in its hospitals set apart for this disease. If the state or the municipality can only do one thing to control tuberculosis, it sliould establish hospitals for consumptives. Control of the Milk Supply. As has been shown, the evidence is pretty strong that a consideralde amount of tuberculosis in human beings is caused by the ingestion of infected milk. This seems to be sufficiently certain to warrant the making of a very strong effort to prevent the sale of 56 THE STATK OONTitOL inilk tVom tuberculous jinimals. This action is tlic more warranted, because it will ultimately l)e to the great advantage of the dairymen, though at first it may cause tliem some trouble and expense. The only certain way to accomplish the desired result is to license all dealers, register all cows, test them with tuberculin, and slaughter all that are infected. Such drastic measures will rarely meet with popular support, l)ut must l)e carried out by numicipalities tliat really desire to protect their milk supply, provided they can secure the necessary legislative authority. If this is impos- sible, as it frequently is, it is w^ortli while to try the Indianapolis })lan and endeavor to encourage dairymen to voluntarily eradicate tuberculosis, in order that they may secure from the city a certificate that this has been done. The Eradication of Ttfherciilosi.s in Cattle. From a review of what has been done and attemj)ted in this line in the United States, it is quite evident that it is impossible to successfully carry out any A^ery dras- tic measures. Little can be done without the co-opera- tion of the cattle owner. The plan which seems to be most successful is for the state to offer its assistance in freeing herds from tuberculosis. If the owner will agree to the application of the tuberculin test, and will agree to improve and disinfect his stables, as required, and thereafter to purchase none Ijut tested animals, the state should test his herd, slaughter and pay for all infected, and assist in disinfection, and, subsequently, ins|)ect from time to time to see that the health of the herd is maintained. It is believed that by thus grad- ually securing healthy herds in different parts of the OF 'iri'.KifcrLosis. 57 state, enough friends will finally be seciu'ed for the carrying out of more radical measures and the compul- sorv cleansing of those herds whose owners still per- sist in maintaining them as foci of the disease. The eradication of tuberculosis in animals, except as it is incidentally involved in the protection of municipal milk siip])lies, had best be attempted by state rather than munici])al aiithoi'ities. To sunnnarize what seems to be feasible for the state at present to attempt in the way of control of tubercu- losis, it may be said : First. Every state or city should require the noti- fication of the disease, and offer assistance in diag:nosis. Second. State and municipal health authorities should do everything possible to educate the people by publications and by verbal instructions, in all cases co- operating with and never superceding the attending physician. Thii'd. The spitting habit should l)e controlled as much as possible, and effort made to instruct and help the consumptive to care for his sputmn. Fourth. Municipalities should assist in cleansing premises occupied b\' consumptives. Fifth. Tlie state or the municipality, or both, should offer hospital facilities for the care of this disease. Sixth. If , j)ublic opinion will warrant, no milk should be sold except from cows tested with tuberculin. If this canncjt l)e done, effort should l)e made to induce dairymen to apply this test. Such work must, at present, be chiefly done by municipalities. Seventh. The state, by means of state officials, slioidd strive to secure the co-operation of cattle owners in the eradication of tuberculosis from their herds, and should test and pay for slaughtered animals. DUE DATE t«Ai i 1 1' 91 jm z 1 ivyi '!.J„ ■ bi- if/- ^ ilf 1 f -i/^ n« VI ^tx5« w. •- V •"■•> , : .-- . . ^ i /CifiS I. jJ^JJWWB Printed in USA «^^^^^^l^,ll^;mSmS^''"' '6023818298 ^;i^pf'iBm%^^