COLUMBIA LIBRARIES OFFSITE HEALTH SCIENCES STANDARD ^a^i^f't.^.-!?;!^ HX64053865 RDil Su7 Surgical clinics i RECAP IN HONOR OF DR. LEWIS STEPHEN PILCHER 1917 bdm 5oT \nti\t€\mtMmff}xk College of ^ijpgiciansi mh burgeons; Eibrarp Digitized by the Internet Archive in 2010 with funding from Open Knowledge Commons http://www.archive.org/details/surgicalclinicscOOmedi IN HONOR OF DR. LEWIS STEPHEN PILCHER SURGICAL CLINICS AND CLINICAL REPORTS IN HONOR OF LEWIS STEPHEN PILCHER Being the Reports of Surgical Clinics at the Hospitals and Clinical Monographs by Surgeons in Brooklyn, New York, to commemorate the completion of his fifty years of service as a doctor of medicine. PUBLISHED BY THE MEDICAL SOCIETY OF THE COUNTY OF KINGS, NEW YORK. 1917 -KJ>\ i-1 PREFACE On the 28th of March, 1866, Lewis Stephen Pilcher received the degree of Doctor of Medicine from the University of Michigan, and entered upon a career, which now for fifty years has been charac- terized by devotion to the high ideals which have won for him the esteem of his profession and the honor and respect of the public. On the eve of the fiftieth anniversary of his entering the medical profession, the Medical Society of the County of Kings, in New York, appointed a committee to arrange for a suitable celebration of the event. A banquet was held on the 12th of May, and on the 11th, 12th and 13th of May, Surgical Clinics were held in the hospitals of Brooklyn and surgical addresses were delivered by Brooklyn sur- geons in his honor. It was to Brooklyn in 1866 that Dr. Pilcher came to begin his medical career. It was at the Naval Hospital in Brooklyn that he en- tered upon the duties of the physician. In this community he has practiced his profession for forty-two years, and for the past twenty- seven years has devoted himself exclusively to surgical work. This volume is a simple expression of the alifection and respect of his surgical colleagues who are his neighbors. The great world of surgery outside of his own community has been glad to do him honor. The surgeons who are his neighbors have been the chief re- cipients of his benefactions because they have enjoyed the privilege of living and working within the close circle of his inspiring influence. This volume contains the reports of the surgical clinics and surgical addresses given in honor of the man and the occasion. James P. Warbasse, Rai^ph H. Pomkroy. Committee. UNITED STATES NAVAL HOSPITAL OF BROOKLYN. NEW YORK SURGICAL CLINICS, HELD AT THE U. S. NAVAL HOS- PITAL, BROOKLYN, NEW YORK. Philip Leach, M.D., Medical Director, U. S. N. C. M. Oman, M.D., Executive Surgeon, U. S. N. E. P. Halton, M.D., Passed Assistant Surgeon, U. S. N. H. F. Lawrence, M.D., Passed Assistant Surgeon, U. S. N. Disi,oCATioN OF Intra- Articular Cartilage of Knee-Joint. N , C.S., Ordinary Seaman ; age 19 ; white. This man was admitted from the U.S.S. Nevada, April 15, 1916, with a diagnosis of dislocation of an intra-articular cartilage of the right knee joint. History. — While exercising in the gymnasium in November, 1915, he fell from parallel bars and struck on the inner right knee. He states that he got up and walked immediately but that the knee felt sore and painful. It was not "locked." He was put to bed at this time and remained in bed for three weeks, receiving the usual hot applications and liniments. At the end of this time he felt much relieved and according to his statement, the pain and stiffness had practically disappeared. However, on resuming his duties he noticed that this knee was distinctly troublesome and that he continually had a sensation of uncertainty as to the manner in which this joint was going to act. Eight times since November, 1915, the joint has be- come "locked" in a semi-flexed position, but he has always been able to straighten it out himself by manipulation. The last time "locking" occurred was one week ago. During the past two weeks he has occasionally complained of pain and stiffness in the joint. Physical Examination. — Examination shows very little difference in the contour of the two knee joints; and there are no signs of effusion. There is distinct tenderness over the position of the right internal cartilage. X-ray examination is negative. Operation by Surgeon C. M. Oman, U.S. Navy. — Ether anes- thesia. A 3''' longitudinal incision is made over internal cartilage : and what hemorrhage there is is controlled by ligatures. Capsule of joint opened and immediately the internal cartilage is seen detached from its normal position and hanging in joint, detached at both ends. Care is taken to use instruments alone in the joint, not touching with fingers. The cartilage is cut at each end and removed. Knee joint flexed and extended to observe condition and to see that no loose bodies are present. Capsule closed accurately with fine catgut and a curved needle. External wound closed by interrupted silk-worm gut sutures. Dry sterile dressing applied and joint supported by a long posterior splint. The splint will remain on for three weeks. Then the patient will be allowed to walk on crutches for two weeks, and at the end of five weeks from the time of operation he will be allowed to bear his weight gradually on this leg. Comments by Operating Surgeon. — The above is a typical history of many cases which are being treated for "sprains," "rheumatism," etc., which really are dislocated cartilages. It is a well-known fact that the internal cartilage is usually the one dislocated, due to the anatomical arrangement of the joint. It has been very rare in my experience to feel any projection on the surface and never have I been able to fix a cartilage before operating, as is mentioned in some works on surgery. Of course it is needless to say that strict asepsis should be fol- lowed. We have operated on a number of these cases and have never seen any ill results. In fact, all the patients have resumed their active duty on board of seagoing vessels without any discomfort. I have been able to follow up a number of my operations on this condi- tion for a period of six or seven years, and all the results have been satisfactory. It seems to me that a great many surgeons are a little shy in opening the knee joint for this disabling condition; they seem to retain the extreme fear and dread which were formerly felt when the knee joint was operated upon. Adenoma of Male Breast. S , S., Machinist's Mate 2nd class ; age 23 ; white. This man was admitted from the U.S.S. Ontario, April 20, 1916, with a diagnosis of adenoma, left breast. History. — In 191 2 he first noticed a swelling in the left breast which seemed to him as an enlargement of the whole breast. The next day the swelling had disappeared. Six months later the swelling again appeared, and has been present ever since. At times, after working hard, the breast became red and painful. Usually it caused him only slight discomfort, and this was more or less imaginary. There never has been any discharge from the nipple and no ex- coriation about the breast. Physical Examination. — Physical examination shows a firm mov- able mass, regular in outline and rather firm in consistency, about the size of an orange and not adherent to the skin or muscles. No secre- tion can be expressed from the nipple. It is tender on manipulation. The diagnosis of adeno-fibroma is made. Operation by Surgeon C. M. Oman, U.S. Navy. — Ether anesthe- sia. The whole breast was amputated by the usual incisions. Very little hemorrhage. Wound closed by interrupted silk worm gut and arm bandaged to side after dressings were applied. Varicocele. - S , R. T., Chief Machinist's Mate ; age 28 ; white. This man was admitted from the U.S.S. Winslow, April 29, 1916, with a diagnosis of varicocele, left. History. — He gives the usual signs and symptoms of a moderate varicocele and recently it has caused him considerable pain and the usual mental worry. Physical Examination. — Examination shows moderately enlarged veins in left scrotum. 10 operation by Surgeon C. M. Oman, US. Navy. — Ether anes- thesia. High operation. A 2'' incision made over external ring; testicle dislocated into wound ; the vas, a couple of small veins, and the cremasteric muscle separated; veins ligated and transfixed; about 2^" removed and ends brought together by a double ligature of cat- gut. The tunica vaginalis cut with scissors and everted. The testicle returned to scrotum and the wound closed by deep fascial catgut sutures, and three superficial silk worm gut sutures. Dry dressings and support of testicle. Patient will be in bed for one week. Comments by Operating Surgeon. — We have found that this method of doing this operation gives very satisfactory results. The dislocation of the testicle permits one to get at the diseased veins, and the cutting of the tunica vaginalis not only does away with swelling of the testicle after the operation but absolutely prevents the forming of a hydrocele some weeks or months later. It is a very quick opera- tion, usually taking about seven to eight minutes. Depressed Scar, FoIvI/)wing Maxillary Sinus. B , J. H., Chief Electrician; age 39; white. This man was admitted from the U.S.S. Florida, October 15, 1915, with a diagnosis of depressed maxillary scar. History. — He has had a chronic sinus of the right lower jaw about seven years. During the past few months he has had the wound opened and the lower maxilla scraped. No dead bone found. The roots of two teeth had been removed. The sinus ceased discharging some weeks ago and the external wound is entirely healed, leaving a depressed scar attached to the jaw bone. Operation by Passed Assistant Surgeon H. F. Lawrence, U.S. Navy. — Novocaine anesthesia. A 2.5 cm. (i inch) linear incision made down to jaw bone. All the tissues were freely separated and the wound closed by three silk-worm gut sutures in such a way as to lift up the depressed portion of the scar and leave a wound in which the scar should be level with the adjacent surface. Deflected Nasal Septum. Case I. S , G. H., Chief Carpenter's Mate ; age 30 ; white. This man was admitted from the U.S.S. Prometheus, April 8, 1916, with a diagnosis of deflected nasal septum. History. — He has complained of nasal obstruction for some years, and has had the usual disagreeable symptoms on catching a fresh cold. Physical Examination. — A marked deflection of septum to the right is discovered. Operation by Passed Assistant Surgeon B. P. Helton, U.S. Navy, Retired. — Cocaine anesthesia. Submucus resection of septum per- formed. Case n. W , H. C, Seaman ; age 22 ; white. This man was admitted from the U.S.S. Wyoming, May 5, 1916, with a diagnosis of deflected nasal septum. History. — He has complained of the usual symptoms resulting from obstruction of the nasal cavities. Physical Examination. — There was a marked deflection of the nasal septum with an old chronic ulceration on the septum. 11 operation by Passed Assistant Surgeon B. P. Halton, U.S. Navy, Retired. — Cocaine anesthesia. Submucus resection of septum per- formed. Deviation o^ Nasal Septum. K , S. G., Seaman; age 21; white. This man was admitted from the U. S. S. Wyoming, May 2, 19 16, with a diagnosis of irregular deviation of nasal septum. History. — He complains of the usual obstructive symptoms and mouth breathing at night. Examination. — Shows a markedly deviated septum to left. Operation by Passed Assistant Surgeon E. P. Halton, U. S. Navy, Retired. — Cocaine anesthesia. Submucus resection of septum per- formed. Hypertrophibd Tonsils and Adenoids. M , N., Female; age 9^; white. This child is a daughter of a Marine Officer. Diagnosis: Hyper- trophy of tonsils and adenoids. Operation by Passed Assistant Surgeon E. P. Halton, U. S. Navy, Retired. — Ether anesthesia. Tonsils removed by dissection and cold wire snare. Curettement of masses of adenoids. Double Inguinal Hernia. L , M. G., Gunner's Mate 2d class ; age 24; white. • This man was admitted from the U.S.S. Arkansas, May 10, 1916, with a diagnosis of a left inguinal hernia. History. — Patient had been operated on for a left inguinal hernia in August, 1913. One month ago he noticed a swelling at the site of the old scar. Physical Examination. — Examination reveals a small reducible indirect left hernia at the site of the previous operation. Examina- tion also shows a small indirect reducible right inguinal hernia. He has not been aware of the presence of this hernia. Operation by Surgeon C. M. Oman, U. S. Navy. — Ether anes- thesia. A Bassini operation performed on each side with the Kocher modification. A small sac containing omentum present on left side and a small sac found on right side. Comments by Operating Surgeon. — This patient will be kept in bed for two weeks. Chronic Bursitis of Toe. C , J. D., Bugler; age 30; white. This man was admitted from the U. S. S. Maine, May 2, 1916, with a diagnosis of bursitis, chronic, metatarsophalangeal joint, left foot. History. — For the past year the patient has been troubled with pain, redness and swelling over this region. The pain becomes much worse on standing for any length of time or upon taking the usual "hike." Physical Examination. — Shows swelling, redness and tenderness over the inner side of joint. Practically no deformity of joint. Operation by Passed Assistant Surgeon H. F. Lawrence, U. S. Navy. — Ether anesthesia. Excision of bursa. 12 Hemorrhoids. Case I. W , F. J., Gunner's Mate 3rd class; age 26; white. This man was admitted from the U. S. S. Wyoming, May 9, 1916, with a diagnosis of hemorrhoids. History. — Five years ago this patient was operated upon for a similar condition. One week ago the hemorrhoids again became prominent. There is some protrusion and they bleed. Physical Examination. — Shows two large bleeding internal hem- orrhoids that cannot be replaced. Operation by Passed Assistant Surgeon H. F. Lawrence, U. S. Navy. — Ether anaesthesia. Sphincter dilated for 5 minutes. Clamp and cautery applied to two sections. One mass ligated by catgut ligature and removed by scissors. Iodoform and opium suppositories. Comment by Operating Surgeon. — Bowels will be kept bound up for four days. Patient will be allowed up after one week and advised as to regularity to prevent future trouble. Case II. — S , C. G., Boatswain's Mate 2nd class; age 26; white. This man was admitted from the U. S. S. Utah, May 9, 19 16, with a diagnosis of hemorrhoids. History. — About one week ago patient first noticed small bleed- ing, protruding mass. Physical Examination. — Shows a small external pile and two small internal piles. Operation by Surgeon C. M. Oman, U. S. Navy. — Ether anes- thesia. Sphincter dilated for 5 minutes. Clamp and cautery applied to two sections. Acute Appendicitis. H , F. A., Ordinary Seaman; age 20; white. This man was admitted from the U. S. S. Wyoming today, with a diagnosis of acute appendicitis. History. — Gives a history of having had acute appendicitis two months ago. Last night he was taken with pain in right iliac region, vomiting and fever. Physical Examination. — Temperature 98.8, respiration 20, leucocytes 30,000, polymorpho-nuclears 90 per cent, urine normal. There is tenderness and rigidity. Operation by Surgeon C. M. Oman, U. S. Navy. — Ether anes- thesia. Gridiron incision, below and external to classical McBurney incision. There is a marked increase in peritoneal fluid. Appendix acutely inflamed, large, and surrounded by plastic lymph. Ligated. Stump cauterized and returned to abdominal cavity. Wound closed in usual manner. Comment by Operating Surgeon. — This man will be kept in bed for ten days. Acute Appendicitis. C , N., Private Marine; age 33; white. This man was admitted from this hospital. May 12, 19 16. He is a member of our marine guard. 13 History. — He was taken sick three days ago with a pain in the region of gall bladder. He was slightly jaundiced at the time. No symptoms referable to the appendix at that time. He was given the usual purgatives. He felt fairly well until last night when he began to have violent pains in the abdomen which became locaHzed in the right iliac region this morning. He vomited. Physical Examination. — There was tenderness over region of appendix, some rigidity. He states he has had a similar trouble once before. Skin jaundiced. No tenderness over gall bladder. Operation by Passed Assistant Surgeon H. F. Lawrence, U.S. Mavy. — Ether anesthesia. Gridiron incision. Peritoneal fluid in- creased; appendix bound closely to cecum and enlarged meso-appen- dix, short and very thick. Appendix removed by dissection. Stump cauterized and gut returned to abdomen. 14 II SAINT CATHARINE'S HOSPITAL. CLINIC AT SAINT CATHARINE'S HOSPITAL. James C. Kennedy, M.D., F.A.C.S. Gentlemen: This clinic is held in honor of Dr. Lewis Stephen Pilcher, one of our most distinguished confreres. He has now reached his fiftieth anniversary as a practicing surgeon. His useful life as a highly respected citizen, an earnest and competent surgeon, and as editor of a widely circulated surgical journal, has given him a high place in the esteem of the people of our city and of his medical and surgical colleagues. By his teaching and example, always the true surgeon and gentleman, the distinguished editor and scholar, he has justly earned his place among the great men of modem times. This clinic, comparatively insignificant, will evidence the gratitude of myself and my colleagues of Saint Cathar- ine's Hospital for the great work Dr. Pilcher has done throughout a long and honorable career. Chronic Appendicitis: Gali* Stones. The first patient for operation this morning is this slenderly built woman, whose age is thirty-nine years. She was born in this country, and is the mother of two children ; she has menstruated regularly and has never had any miscarriages. Her previous history is negative, except for the diseases of childhood. She states that two years ago she began to have attacks of pain in the right iliac fossa, and that, in addition she has had almost a constant feeling of fullness and heaviness in the right hypochondrium, accompanied by a dragging sensation over the hepatic area. This patient was sent into the hospital with a diagnosis of chronic appendicitis which we believed to be cor- rect; still we do not believe that all the symptoms stated are due to appendicitis. Laboratory findings together with the x-ray examina- tion, are negative. However, in the prone position, palpation over the region of the gall bladder elicits soreness, but not sharp pain ; the same is found in that portion of the liver, bounding the gall bladder. These are two symptoms that I hold in high regard in gall bladder disease. She has never had biliary colic or jaundice, but when the abdomen is open we must not forget to examine the gall bladder. Our incision is made below the umbilicus, through the right rectus muscle. We are now in the peritoneal cavity, and find a chronically inflamed appendix which we will remove; the stump is inverted ac- cording to the Dawbarn method. I now place my right gloved hand into the peritoneal cavity; the uterus and ovary are correct, — now upward, and I find everything normal, with the exception of the gall bladder which is filled with calculi. We will now close our appendiceal wound, and, using the Mayo Robson incision, do a cholecystostomy for cholelithiasis. On opening the gall bladder in the usual way I am able to remove these stones with the forceps. Each stone, as you see, is about the size of a small bird's egg. 'This is the last one, making 17 thirty-two calculi in all. With the duets now freed, we will drain the gall bladder as it is done ordinarily. We all know that calculi may exist in the gall bladder or in some portions of the bile ducts without giving rise to any symptoms, or at least so few that it is almost impossible to make a diagnosis of their existence. This statement is borne out, in some degree, by this case. GaIvI. Stonr Disease. Here is another operation for gall bladder disease, but it differs materially from the case we have just concluded. The patient is a stout lady, and on referring to the History we find her weight to be l8o pounds, her age is fifty years, she was born in this country, and is the mother of four children. There is a scar in the lower abdomen, but the patient was unable to state the reason for the operation which it marks. She has had paroxysms of pain, chills and jaundice for four years. From the time of her arrival at the hospital she has had all the classical symptoms of obstructed gall bladder disease. On opening the abdomen, we find, with the exception of the hepatic ducts, that the biliary canal is filled with calculi. Since this is so, the obstruction to the flow of bile into the intestinal canal must be in the common duct — here is a large stone lodged at the ampulla of Vater. This was surmised because of her jaundice. As you know, jaundice is produced by the passage of bile and its coloring matter from the liver into the lymphatic vessels and the blood. Its essential cause is obstruction of the outflow of bile into the intestines. The obstruction does not prevent the secretion of bile by the liver, hence there is a consequent dilatation of the biliary ducts and canals, stagna- tion of their contents, and absorption by the lymphatics of the biliary coloring matter and acids which reach the general circulation by way of the thoracic duct. The biliary acids have the power of destroying red blood cells, thus setting free hemoglobin — the free hemoglobin increases the formation of bilirubin by the liver and so may serve to intensify the jaundice. The characteristic lemon-colored appearance of the skin and conjunctiva and urine are noted at this stage. The feces become clay colored, owing to the absence of coloring matter, and we often have constipation accompanying these cases, with alter- nating attacks of mucous diarrhea, as a prominent symptom. We will now open the gall bladder, and we find many small stones floating in the dark colored fluid. These are removed with the scoop. The calculi in the cystic duct are easily milked up into the gall bladder and removed. Here in the common duct, however, is quite a large stone which we can neither push upwards nor down into the duodenum. I am unable to crush the stone with my fingers — and I never use a forceps for that purpose lest the walls of the duct be damaged per- manently, — so we will do a choledochotorhy ; here is the stone. You will note the free discharge of bile which flows into our laparotomy pads and which we will continue to sponge away until it stops. Two catgut sutures are placed through the edges of the cut into the com- mon duct, and passed around a long, dressed, rubber tube, fenestrated at its lower end. These sutures will hold the end of the tube in place for about ten days. Two heavy strips of iodoform gauze are placed on either side of this tube, and will be left in place several days after the tube is removed. The gall bladder is also drained with rubber tubing, and the abdomen closed in the usual way. 18 Chronic Appendicitis. This is a case of chronic appendicitis. Our patient is a young girl of seventeen years, born in this country. For the last year she has had variable symptoms, paroxysmal pains being the most constant ; these were confined to the right iliac fossa. Associated with this there has been intestinal indigestion, alternating with mucous diarrhea and constipation. The patient is extremely nervous — a symptom very prevalent in chronic appendicitis. The right rectus incision is the one we will use, pulling aside the muscle after dividing its anterior sheath, and incising the posterior sheath and peritoneum which leads us into the peritoneal cavity. With the finger we endeavor to hook up the cecum, but we are prevented from doing so, with the freedom we usually experience, because of the adhesions. We find the appendix somewhat chronically inflamed and enclosed in a well formed pocket. Bands running from the ileum to th-e cecum constitute this ; here in the cecal wall I find a hard mass snugly imbedded. We will remove this. It is, as you see, a calcified body, about the size of a ten cent piece. It is white and hard, and may be a calcified gland or a small ruptured blood vessel which has undergone calcification. Perhaps it was this which caused the adhesions, through irritation and the resultant inflammation. We will send the specimen to the laboratory and perhaps the pathologist will be able to help us out. The appendix is somewhat thickened ; we will remove it, and invert the stump according to the Dawbarn method. Fracture oe Pelvis; Rupture of Bladder. The last case for operation today is this small boy who was brought in by the ambulance this morning. He is twelve years old. Several hours ago, he climbed upon the seat of an automobile truck while the driver was delivering goods. He started the machine, and then becoming frightened, jumped from the truck and fell under the wheels. The rear wheel passed over him, causing a comminuted frac- ture of the pelvis and rupture of the bladder. We thought that he would die, soon after his arrival in the hospital, from shock, but he is still alive and has some pulse. We bring him to the operating room because it is impossible to pass a catheter into his urethra, and because, as you see, his pernieum is bulging to an alarming extent from extra- vasated urine. We will make a single incision into the perineum, and you see the large amount of bloody urine which escapes. We believe this to be a humane thing to do, notwithstanding the fact that we do not believe the boy will live. By passing the finger through the wound we find the pubic bone torn from its mooring, and lying on the rectum. The ileum is fractured in several places. We will do nothing further now, except to place a drain in position to carry ofif the extravasated urine. We must await developments. 19 THE TREATMENT OF GALL-STONE DISEASE. Mathias Figueira, M.D., F.A.C.S. Case L This patient came to the hospital with the history of stom- ach trouble and more or less pain for a number of years. She remembers suffering severe pains at intervals, several years ago. She had no severe pain lately but has suffered from stomach and intestinal trouble in the form of indigestion and constipation. At admission to hospital besides the above symptoms she did not present anything noticeable except a quite marked tumor under the right costal border moving with respiration and continuous with liver. It was not very tender and abdomen did not show any marked signs except moderate distension. At operation the tumor was found to be caused by a very much enlarged gall bladder, containing fifteen stones, one of them as large as a pigeon's egg. It weighed 130 grams. The length was 15 centimeters and the greatest width 6 centimeters. The walls were 5 millimeters in thickness. On section it showed the lesions of chronic inflammation. Patient made a good recovery and is now well. Case; II. The second case I report, came under by care two years ago. A young woman was taken with abdominal pain that soon centered under the costal border on right side and required hypo- dermic injections of morphine for relief. After pain subsided her stomach was so irritable that rectal alimentation had to be resorted to for several days. Under the most careful dieting and care she recovered but was soon taken with a similar attack and that followed by another at such close intervals in spite of the best care and advice that operation had to be done to save her from grave complications. She is now well. Comment. — That once the diagnosis of gall stones is made, opera- tion is the best treatment, all surgeons are agreed. The internists, many of them, still claim that a good many cases of gall stones can be cured by medicine and proper dietetic treatment. It is certainly possible for gall stones under rare conditions to pass into the intes- tines and be eliminated that way, and anyone who has seen much of gall stone disease knows that under medical treatment many cases will very much improve. The attacks of pain will disappear, the diges- tion will improve, the appetite return and such patients seem to re- cover and remain comparatively well for months, sometimes for years, and the doctor who treated them will enter them in his records as cures. Months or years afterward when the patient has passed out of the doctor's memory, probably out of his neighborhood, as such cases often do, another doctor will get the case and will have to operate on it to save life. The first case reported in this paper is probably such a case and is down in somebody's book as a cure of gall stones by medicine. I have no doubt that if the history of cases that come to the operating table with such grave complications as adhesions, per- foration, involvement of neighboring organs, stricture of duct — if the 20 history of such cases were carefully traced, the history of gall stones "cured" by medicine would be elicited. Medical treatment bears the same relation to these cases as the ice bag does to complicated appendicitis cases. As for those corresponding to the second case here reported, even the internists will admit the urgent indication for surgical inter- ference. It is very important, I believe, to bear in mind that of all organs the stomach oftener presents symptoms caused by disease in other parts, and the gall bladder, in many cases of obscure and insistent stomach trouble, is the organ at fault. Appendicitis and gastric ulcer have often been operated upon when the gall bladder was affected and gall stones were the cause of the trouble. The statement of Dr. Mayo of Rochester in a recent publication that, of 375 cases of gall stone disease coming to his clinic for opera- tion, 13 per cent had been previously operated upon for the wrong disease, should be a warning and a lesson to all of us. And the practice of exploring the gall bladder in all abdominal operations is a wise one as gall stones are often present with other abdominal diseases. I know of a case in which the surgeon operated for salpingitis with abscess. He was wise enough to explore the gall bladder which he found was full of gall stones. He did not remove them as the patient's condition did not permit, but afterward informed her of the condition. Within a few months symptoms of gall stones developed and he operated with success and credit. Had he neglected to examine the gall bladder and inform his patient when symptoms of gall stone developed afterward, the chances are he would have been accused of operating for the wrong disease. When the diagnosis of gall stone disease is once made what operation is the best to perform ? Keen's Surgery, the latest standard work, published only a few years ago, contains the following state- ment by the leading surgeons of the country on gall bladder surgery: "Cholecystostomy we consider the normal operation for gall stones." In 1,600 cases of gall stones reported cholecystostomy was performed in 1,200 cases (just three-fourths of all cases) with a mortality of less than 2 per cent. Since the above statement and statistics were published quite a change has taken place in the practice and teaching of some leading clinics in this country, and cholecystectomy is now considered the best operation for gall stones with a mortality a little less than cholecystostomy. Statistics, published last year from the Mayo Clinic at Rochester, show a total of 763 operations for gall stones. Of this number 589 were cholecystectomies and 74 cholecystostomies. This is a complete reversal of the practice and results of a few years before. There is no doubt that the above results can only be attained with the unusual skill and experience of the surgeons at the head of that clinic. Cholecystectomy requires more skill in its technic and greater care to avoid injury to the bowel, the vessels and main duct. This is the statement made by Dr. Mayo in comparing the two operations. I believe statistics from other clinics and from the general practice of surgeons will give different figures corresponding rather to the figures in Keen's Surgery. The statement of Crile, that the cases of cholecystostomy that came back to the surgeon are the cases in 21 which the gall bladder was diseased or the mucous membrane in- flamed or the cystic duct closed or some other lesion present besides the gall stones, is certainly true. If at operation the gall bladder has a normal appearance, the mucous membrane is not markedly altered, the bile flows freely and looks natural, I believe cholecystostomy is the best operation in the hands of the general surgeon. Maybe it does not speak for so much surgical skill but the curing of disease and saving of life is the main thing. When on the other hand if the gall bladder is changed by in- flammation or disease, when the mucous membrane is altered or degenerated, when there is empyema or obstruction of duct, then cholecystectomy is the operation and the surgeon not equal to it should pass the case to better hands. There are, however, cases in which the indications are not so clear and distinct, border cases as it were. If I am permitted an opinion I would say that in general surgical practise, with the skill of the general surgeon at hand, the patient should be given the benefit of the doubt and cholecystostomy performed. If perchance he should be one of the cases that come back then cholecystectomy can be done. Quoting again from a noted surgeon, "the drainage operation may be chosen for primary safety with later cholecystectomy recom- mended as a probable necessity in the future, a two stage operation." I will conclude by saying that when the deep sea captains follow such opposite routes, it behooves the skippers of smaller craft to sail by 'the dead reckoning of judgment and prudence, rather than by the sun and stars. 22 Ill ST. JOHN'S HOSPITAL. SURGICAL CLINIC AT ST. JOHN'S HOSPITAL. Warren L. Duffield, M.D. Probable Fracture of Base oe Skull, Immediate Decompression. Clinical History. — A male 60 years of age was brought to the hospital about midnight with the history of having been struck by an automobile. When admitted he talked in an irrational manner, was actively delirious, requiring restraint, and his pupils were said to have been unequal. When seen about one-half hour later he was in a deep coma and could not be aroused. Examination revealed four wounds of the head and a fractured nose. One wound directly over the sagittal suture was incised and a small portion of the bone had been gouged away but there was no demonstrable linear fracture. The other wounds were not complicated by any traumatism to the bone. The pupils were now equal, contracted and slowly responded to light; the pulse was 90 and of good quality. Slight patellar reflexes could be elicited after some effort. There was tonic muscular spasm of all extremities but slightly less pronounced in the left forearm. During the course of the examination there had been no active movements of the extremities. Upon exploring the scalp wounds all extremities with the exception of the left arm were moved by the patient, but with no apparent return of consciousness. Upon further examination of the left arm it was found to be flaccid with the exception of the adductors which were in a condition of tonic muscular spasm. A right temporal decompression was decided upon. Operation. — Without any anaesthesia and through an inverted U incision over the right temporal region the fibres of the muscle were separated and the skull opened with a Hudson drill and the opening enlarged with rongeur. There was no bulging of the dura but upon opening it cerebrospinal fluid escaped in large quantity and with considerable force. At first the fluid was perfectly clear but as it con- tinued to flow it became markedly blood stained. Up to the time of opening the dura the patient had been quiescent but as soon as the fluid began to escape he commenced to talk in an incoherent manner and began moving his extremities. The brain substance was dark in color but there was no tendency to hernia. A rubber tissue drain was introduced to the dura, the muscles sutured over and the flap accu- rately restored. Post-Operative History. — The average pulse, temperature and respiration for several days were respectively 100, loi 1-5 and 30. His blood-pressure six days later was 90 and 120; and twelve days after operation no and 135. For about ten days there was an active delirium almost every night and a mild delirium during the day, though when spoken to he would answer in a rational manner and as a test was able to read a newspaper. At present his pulse and tem- 25 perature are normal and only occasionally is he slightly irrational at night. All bodily functions are apparently normal and there is no paralysis. Comments. — Dr. William Browning made an examination sev- eral days after the operation and expressed the opinion that the delirium was due to an old and chronic alcoholism. It is of course an open question whether this patient would not have recovered under expectant treatment but as all symptoms of intracranial injury had apparently increased during the first hour and a half of observation an exploratory craniotomy was decided upon and the results would seem to justify the decision. Gastro-Enterostomy for Duodi;nai, Ulce;r. Clinical History. — The patient is a married woman, 38 years of age, whose family history is negative except for the death of one sister from tuberculosis. The patient had an attack of pneumonia seven and one-half years ago, had puerperal peritonitis eight years ago, and has given birth to seven children. Twice during each of the past six years she has had attacks of profuse hemoptysis with severe pain in the epigastrium. Her most severe attack was in Sep- tember, 1914, when in the course of two weeks she had fourteen hemorrhages. Her present illness began one week ago and during that time she has had eight hemorrhages each lasting about five minutes. Repeated doses of coagulose were given by her physician, Dr. C. B. Cortright, to control the bleeding, as at this time she would not consent to operation. Her epigastric pain is somewhat relieved by vomiting. There is macroscopic evidence of blood in the stools. She is the sub- ject of a mild pulmonary tuberculosis, though at present tubercle bacilli cannot be demonstrated in the sputum. In May, 191 5, she was twice operated upon, once for the removal of a diseased ovary and later for the removal of the appendix. Examination is practically negative except for a small point of considerable tenderness in the epigastrium. The stomach contents are acid, free HCl 15, combined acid 27, total acidity 46. No lactic, acetic nor butyric acid present. Maltose and pepsin and a large amount of mucus present. Microscopically a trace of blood, many fungi and many starch granules can be found. Her blood count is red-cells 3,950,000; leucocytes 6,800; hemoglobin 90 per cent, and polymorphoneuclear cells 69 per cent. Examination of feces reveals a small amount of blood. X-ray plates show a filling defect of the pyloric end of the greater curvature and the duodenum immobilized to the left of its normal position. There is an overlapping of the duodenum and pylorus and a consequent blurring of the picture. Operation. — Through a vertical right rectus incision an ulcer about one and one-half cm. in diameter can be distinctly palpated in the inferior wall of the duodeno-pyloric junction and at this point there are numerous thin but firm adhesions. The duodenum and pylorus are drawn upward and to the right by thin but firm perigastric adhesions which extend downward across the duodenum and pylorus. A typical Mayo posterior gastro-enterostomy is now performed with- out difficulty except for posterior perigastric adhesions, similar to those above noted and which require division before the stomach wall can be drawn through the meso-colon. 26 Comments. — After the abdomen was opened and before perform- ing a gastro-enterostomy a Finney pyloroplasty with resection of the ulcer, or a simple resection of the ulcer followed by a posterior gastro- enterostomy were both considered but abandoned because of the im- mobility of the pylorus due to the perigastric adhesions which would have required considerable time for their dissection. With the patient's history of pulmonary tuberculosis it was considered wisest to do the simplest and quickest operation which would give relief, and this seemed to be a posterior gastro-enterostomy. Post-Operative History. — For seven days her recovery was smooth and uninterrupted and all sutures were removed. On the eighth day vomiting began and became more constant, the vomitus consisting mainly of bile. On the tenth day the abdomen was again opened and the second operation revealed the meso-colon folded on itself and firmly adherent over the anastomosis producing an obstruction. Fol- lowing the second operation there was slight and diminishing vomit- ing. At this time her convalescence is well established. Comments. — There are two features of interest in this case. Be- fore operation the hemoptysis had been so pronounced that she was quite exsanguinated, yet seven days post-operative, though the vomit- ing was constant and persistent for about forty-eight hours, there was not the slightest evidence of blood. A fair assumption would seem to be that the ulcer had become quite firmly healed in the' interval. The second point of interest is that in spite of a very easy gastro- enterostomy, excepting for a few posterior perigastric adhesions, and with but little handling of the intestines very dense adhesions were found across the entire meso-colon on the tenth day. These adhesions were out of all proportion to the traumatism inflicted and were more extensive and greater than we have ever seen under the same condi- tions. Can it be that the repeated doses of coagulose had increased the viscosity of the peritoneal fluid and thus favored the formation of early and dense adhesions? Stab Wound of the Abdomen Involving the Liver, Stomach and Omentum. A colored boy of nineteen was brought into St. John's Hospital by the ambulance, suffering with an incised wound of the abdomen and stating that about one-half hour before admission he had been stabbed. Examination reveals a well developed muscular youth with an incised wound 2 cm. long slightly to the left of the median line at a point midway between the ensiform and the umbilicus, and protruding from the wound is a mass of omentum 2 cm. wide and 7 cm. long. The pulse is 76, regular and of excellent quality, the temperature is normal and there is no vomiting, abdominal rigidity nor complaint of pain, and no evidence of shock. Operation. — A vertical incision is made 2 cm. to the right of the wound and reveals an incision passing through the edge of the liver. The liver is sutured on both surfaces. There is also a wound 2 cm. long in the anterior wall of the stomach through which gas can be seen bubbling. A double row of Lembert sutures are here intro- duced. No further injury can be detected on the right side but on the 27 left two severed omental vessels which are bleedjng briskly axe ligated. The base of the protruding omental mass is now ligated and sectioned within the abdomen, a cigarette drain introduced to the neighborhood of the opening into the stomach, the operative wound closed in layers, the protruding omentum removed and a small drain superficially introduced into the stab wound. In order to pre- vent all further infection of the abdomen the protruding omentum was carefully excluded from the operative field before beginning the opera- tion and was not touched until after the laparotomy wound was closed. Post-Operative History and Comments. — Following operation there was no vomiting, fluids by mouth being withheld for forty-eight hours, during which period Murphy drip was administered. At no time was there evidence of peritonitis and the drains were removed on the fourth day. A satisfactory and prompt recovery was made, and the patient was discharged fourteen days from the receipt of the injury. This case serves well to illustrate the absolute necessity of ab- dominal exploration in all cases of penetrating or suspected penetrat- ing wounds of the abdomen, a practice which is or should be universal. Assuming that there had been no protruding omentum one might have felt almost justified in awaiting the development of symptoms for there were certainly none present to indicate serious injury. To have delayed, with actively bleeding omental vessels and a penetrating wound of the stomach wall, would have been to have waited too long. Acute Intejstinai, Obstruction Due to Procidentia Uteri. This case is reported because of its apparent rarity. The index of the first sixty volumes of the Annals of Surgery does not record a case. Clinical History. — A Hebrew woman of 57 years was admitted to the hospital and the only history that could be obtained was that twenty-four hours previously vomiting had begun and had increased in frequency until at the time of admission it was constant. Examination revealed a woman who appeared very much older than the age given. She was very poorly nourished, her pulse was weak and thready and the abdomen markedly distended. She was constantly vomiting small quantities of fluid almost black in color. Protruding from the vulva was a mass under considerable tension which consisted of uterus, bladder and rectal wall — a complete pro- cidentia uteri. All hernial openings were carefully examined but nothing abnormal found. We were unable to determine from her how long she had suflFered with a procidentia or whether it had increased in size or had changed in consistency coincident with the onset of vomiting, but received the impression that there had been some change in it at this time. Feeling that the cause of her obstruction was a strangulation of bowel in the everted vagina, but not being able to exclude other possible causes, it was decided to reduce the mass and wait for an hour, as her condition did not seem to warrant any greater delay. She was placed in a slightly exaggerated Sim's position, the mass re- duced without great difficulty and the vagina tamponed. One hour later, the vomiting still persisting, her abdomen was 28 opened through a right rectus incision. Upon passing the hand down into the pelvis a large mass of small intestine could readily be dis- lodged. The intestine was dilated to about three times its normal size and was of a deep bluish color. The large intestine from the rectum back to the cecum was thoroughly but quickly inspected and found to be collapsed. The ileum was found to be collapsed back to a point about 45cm. from the cecum and at this point there were no definite signs of obstruction. Proximal to this point the intestine was found distended and congested and distal to it collapsed and light in color. Upon handling the bowel the fecal current passed on and into the cecum. The uterus was drawn up and rapidly fixed to the anterior abdominal wall and the abdomen closed as quickly as possible. It was doubtful whether she would live through the operation; but under stimulation the operation was completed. She died about five hours later. Though no definite point of obstruction was demonstrable it is our opinion that the obstruction was due to the gut being forced into the sac formed by the everted vagina — a form of intestinal obstruc- tion which we have not seen recorded. 29 IV THE LONG ISLAND COLLEGE HOSPITAL. CLINIC AT THE LONG ISLAND COLLEGE HOSPITAL, MAY 12, 1916. Wm. B. Brinsmade, M.D. and James Watt, M.D. Inguinai, He:rnia. THE patient is a man, thirty-five years of age, who three months ago first noticed pain in his right inguinal region. This was not brought on by any particular muscular effort, although his ordinary vocation is one that entails hard work. Since its inception the pain has gradually increased and is now fairly constant. Six weeks ago he first noticed some protrusion in the painful region. This protrusion has gradually increased in size, is now a constant annoy- ance and hinders his work. On examination, the patient standing, a protrusion the size of an egg is visible emerging from the inguinal canal. On percussion this tumor gives a resonant note and on manipulation disappears within the abdomen with a gurgle. The history and results of the examina- tion indicate the presence of a complete inguinal hernia. The ques- tion arises whether such a case is one for which an operation should be done or not. All operations are operations of either necessity or election. When an operation is necessary a considerable risk to the patient must often be assumed by the operator, whereas in opera- tions of election a surgeon should not assume any risk that can possi- bly be avoided. A hernia such as the one under consideration might be held in place by a truss, but a truss is a very inconvenient and troublesome implement to wear, if one is to earn his living by hard work. We know also that a truss will not cure such a hernia as this, and notwithstanding that a truss may suffice to retain the hernia under ordinary circumstances, it not infrequently happens that in spite of the presence of a truss the hernia escapes under special con- ditions of exertion and is strangulated, the very presence of the truss adding to the dangers of strangulation. In this particular patient the records show that his kidneys, heart and lungs are all in good condi- tion and we have therefore advised an operation, since in more than 95 per cent of the cases done in this clinic a permanent cure has been secured by operation. The surgeon has at times been called upon to give an opinion as to whether a certain hernia was caused by an accident. The teaching in this clinic is that there must be two causes for hernia ; first, a predisposition by way of weakness in the abdominal wall and second, increased abdominal pressure. Without both these factors at work it is doubtful if a hernia would ever occur. The method of operating adopted by us is that known as the Bassini operation ; so far it has given in our hands perfect satis- faction. In m.ost cases the person has but little ether, he seldom vomits and there is no shock. Our rule is to keep these cases in bed for 33 eight days. Upon the ninth day he is allowed to sit up in a chair, and thereafter to walk around as strength returns. The cases are dis- missed on the fourteenth day after operation with definite instruc- tion to have the bowels move daily, and to engage only in moderate exercise ; to avoid lifting of heavy articles for six weeks, after which time they are permitted to take up their former method of living. Fracture of the Patella. A man forty years old, while walking in the street, caught his foot against an obstacle and, in an effort to save himself, threw his body backward. As he did this a snapping was fell in his right knee; he sank to the ground and found to his surprise he could not lift his right leg. He was taken home and an evaporating lotion was applied to the knee for two days when he was sent to the hospital. When ad- mitted the right knee was swollen and the patella was found to be the subject of a transverse fracture, with separation of the two fragments so that a finger could be placed easily between the two. He has now been three days in the hospital, five days have passed since the occur- rence of the accident. There is considerable redness and swelling about the injured knee, and it is evident that the knee joint is filled with bloody fluid. What is the best thing to do for this man? The prime necessity is for him to get back to his work with a sound limb in the shortest time possible. An absolute bony union of a broken patella is not essential to excellent function. There- fore, if operation is done upon this man simply for bony union, the operation would be one of election and not of necessity. The patient is advised to have the knee joint opened, the blood removed, and the broken and lacerated tissues restored to their normal positions, and we feel safe in promising him that he will have a more perfect result in a shorter period of time by such procedure than by waiting for healing to take place without operative interference. We had in- tended to perform this operation this morning, but we find that there is still present much evidence of reaction in the tissues with consider- able infiltration of blood. Realizing that the knee joint is the largest joint in the body, and that the slightest infection may lead to the loss of the joint, or even of the leg, we think it better to postpone surgical interference until the tissues are restored to a more normal condition. When we do open this joint with a curved transverse incision we shall find that not only the patella is broken, but that both lateral ligaments are torn well down on either side of the joint. We wih also observe that when the lacerations of the lateral ligaments have been repaired, the broken fragments of the patella will have almost restored them- selves to their proper position. The dense fibrous fascia, covering the anterior surface of the patella, will have been torn across and its lacerated edges will have dropped down like a fringe between the fragments. These fibers are lifted out and the fascia sutured with a few fine catgut sutures. After the operation the extended leg will be put in a plaster case, and the patient confined to bed for seven days, at the expiration of which time the case will be taken off and the skin sutures removed. A lighter case is then applied and cut into anterior and posterior sections. The patient is allowed to get out of bed and sit in a chair for the next five days, at the expiration of which time the case is left off while the patient is in bed and reapplied every time he gets up. After eighteen days passive motion and massage 34 are practiced and the patient is encouraged to bend the knee. This method of treatment is kept up until the patient is able to flex his knee to a right angle, after which he is discharged with instructions to carry a cane in the streets constantly for the next two months. Such care and help is important to avoid dangers of refracture. The functional results from the closed method of treatment are often so excellent that a surgeon is not justified in urging an opera- tion in all cases of fracture of the patella. Such an operation should never be performed except under the most rigid asepsis. In this clinic we never put anything into a wound which has not been boiled ; the operator and assistant should leave an operation with their gloves as clean as when they commenced ; the blood clot being removed with toothed forceps and a spoon curette. If there is any question about the desirability of doing an open operation, always decide in the nega- tive. One should be perfectly sure that the tissues have a normal amount of resistance, and that the surroundings are surgically perfect. It is for this reason, therefore, that operation on this patient is post- poned until a future date. Choi,e;cyste;ctomy for Chronic Ini^lammatign of thf Gai^i, Bladder with Gali, Stonfs. The patient is a woman forty-two years of age who was brought to the hospital six days ago, suffering acutely with pain in the upper right quadrant of the abdomen and over a small area in the back close to the spine. She had been vomiting for two days and had a tem- perature of 1023^ and was jaundiced. During the past six years she has had from time to time attacks similar to the present one, but never so severe. She has had two pregnancies during this period and during each pregnancy has had several attacks similar to the first one. There was bile in her urine and her stools were clay colored. She commenced to improve as soon as she entered the hospital and her jaundice has almost disappeared. We never operate upon any cases of pronounced jaundice where it is possible to postpone operation. The patient describes so-called bilious attacks as occurring from time to time and not associated, in her mind at least, with the ingestion of or abstinence from food. She is a well developed women of good frame. It is fair to assume an obstruction to the flow of bile. I want to call particular attention to Boas' sign which is pain over a restricted area in the back, directly behind the region of the gall bladder. I have never failed to find stones in any case in which this symptom was distinctly present, but on the other hand I have often found stones where the symptom was not present. With such a his- tory and condition as has been described one is justified in urging an operative procedure because it is certain that she will never be well of these attacks until the cause is removed, and that she may develop conditions which might become rapidly fatal. Mere pres- ence of gall stones alone does not demand operation, since statistics show that in a large percentage of all adult cadavers gall stones are found. The patient has accepted our advice and is ready for operation. As the ciher is administered it is noticeable that she takes it well. A pad placed under her back brings the liver well to the front. A trans- verse incision is made through the right rectus muscle, about I inch below the border of the ribs, because it seems to give a wider field 35 for easy operative manipulation, and also because it is easier to close. I do not know who first suggested this incision, but I saw it used in Germany many times several years ago, and more recently it has been brought to the attention of American surgeons by Dr. Moschcowitz of Mt. Sinai Hospital, New York. After the abdomen has been opened a large sheet of gum rubber is placed so as to cover the exposed intestines, and on this rubber the gauze sponges that are used are placed. Thus these sporgcs absorb whatever discharge there may be without coming in co'iiact with the intestines. I believe this pro- cedure to be of considerable value in prevention of that abomination of abdominal surgery, adhesions. The region having been oriented we discover a small gall bladder with thickened walls, within which just as it narrows down to the cystic duct a stone can be felt. The neck of the gall bladder is tightly contracted on it so that it cannot be pushed up into the fundus of the gall bladder. The entire gall bladder and cystic duct are hard and thickened. Nothing is discovered in the common duct by palpation. We have then to deal with a diseased gall bladder and duct containing a stone. In our opinion this gall bladder is diseased beyond repair and must be removed. If left behind and drained it will merely become a foreign body. The cystic duct is therefore caught in a right angle clamp, by blunt dissection the cystic artery is separated and tied. The duct is then cut across be- tween tv/o clamps and the gall bladder removed from behind forwards, leaving the surface of the liver which oozes very slightly. A long probe is then passed through the duct into the common duct and the ampulla of Vater for exploration. No obstruction is discovered. The duct is then ligated. A long cigarette drain is fastened to the duct and another drain, containing a split, soft rubber catheter, packed with gauze, is placed beside it. Notice that both these drains are covered with gutta percha tissue so as to prevent any irritation which might set up adhesions. All sponges are now removed and counted. There is no moisture at the bottom of the wound or around the liver so the rubber dam is removed. We are sure that this woman will be restored to her family in three weeks in better health and with a better disposition than she has had for a long time. Whenever you find either a man or woman who is cranky and disagreeable to live with, do not put it down to disposition or cussedness until every effort has been used to find a local or pathological cause. In this connection I Vv^ould impress upon you once more the necessity of arriving at a diagnosis first, by the history ; next by examination ; and finally as an addendum to these, the use of the laboratory. Do not learn to depend entirely upon the X-ray for diagnoses ; valuable as it is, it is sometimes deceptive and sometimes also it fails to reveal the condition which is present. 36 ArtificiaIv Anus. In certain cases of cancer of the rectum when the entire rectum can be removed by the combined abdominal and either perineal, sacral or vaginal operation, it becomes necessary to create an artificial anus. The comfort and effectiveness of the new opening determines the well-being of the individual. For the satisfactory control of an artifi- cial anus we have found that the following method gives the best results : A transverse incision is made above the pubes, and the sigmoid isolated. The gut is then cut across well above the growth and a second small incision is then made through the skin about 2^^ inches above the transverse incision and to the left of the median line. This brings the opening well above the pubic hairs. By blunt dis- section through the fibres of the rectus, keeping well in front of the peritoneum a passage about 2^ inches long is created down to the transverse incision. The proximal cut end of the gut is drawn through this passage and fastened to the peritoneum at this point of entrance in the abdominal wall and to the skin at its exit. The operation for the removal of the cancer may be performed at this or subsequent sitting. The effect of this procedure is to create a loop or segment in which fecal contents may collect beyond which there is a perpendicular passage through the rectus muscle which seems to compress the bowel and control its contents to a mild degree. I have used this method six times, and my friend. Dr. Fiske, has used it four times, and the re- sults have been satisfactory in all these cases, both to ourselves and to the patients. I now present a patient who is the subject of an artificial anus thus made. A woman, who was operated upon eighteen months ago on account of a growth in the rectum. The operation was performed as described. The after course was hard for several months owing to a large amount of tissue-sloughing through the peritoneal vaginal wound. She has now gained weight and recovered full strength and considers herself a well woman again. The artificial anus functionates in a very satisfactory manner; by using a small syringe each morning she is able to empty her bowel of the fecal contents. It takes her about one-half hour each morning to perform her toilet for the day. She wears no cup and only a simple compress made of a few layers of gauze and cotton, which is pinned to her undervest. I believe this is far better than any other form of artificial anus. As far as I know this particular procedure has not been described. I have re- served any description of this procedure until it had been performed several times, and am now glad to present it to Dr. Pilcher on the occasion of our celebration of his fifty years of devotion to humanity and science. 37 THE DIAGNOSIS OF FRACTURE OF THE NECK OF THE FEMUR. John D. Rushmore, M.D. THE following remarks apply to the diagnosis of fracture of the narrow part of the neck of the femur, or intra capsular fracture. In the large majority of patients with suspected fracture of the femoral neck the diagnosis is not difficult ; in a few cases one may feel uncertain whether a fracture exists or not, without the evidence fur- nished by a satisfactory skiagraph. On the other hand, before the use of the x-ray, cases have been reported as fractures when a post mortem has failed to show the fracture ; and even experts may differ in the in- terpretation of a clear skiagraph, as to whether a fracture exists or not. And inasmuch as the x-ray apparatus cannot be used in a large per- centage of cases, for various reasons, one is obliged to fall back on the long list of symptoms that are, singly, uncertain, but taken in their totality, render mistakes in diagnosis very exceptional. Considering then the symptom on which we base a diagnosis of fracture of the neck of the femur, the most positive evidence for or against the existence of a fracture is furnished by a good skiagraph, when it can be obtained. Next to a skiagraph I have depended on a symptom or sign which is as evident to the eye as Allis's sign is to the touch. Place one end of a tape measure over the anterior superior spine of the ilium under firm pressure of the finger or thumb ; have an as- sistant draw, by traction on the foot, the limb downward to its utmost length without inflicting pain ; place the taut tape where it comes op- posite to the inner malleolus over that bony point under firm pressure with the thumb of the other hand, and then, being careful that the knee of the patient is kept rigid, have the assistant shove the unbent limb forcibly but slowly up toward the pelvis, and if there is relaxation of the taut tape visible to the eye, a fracture of the neck of the femur exists. If the same procedure is used on the opposite limb there is no relaxation of the tape. The amount of relaxation that takes place will depend upon the presence or absence of impaction. This sign has nothing to do with mensuration ; any flexible and inelastic material can be substituted for a tape measure ; even the edge of the sheet covering the patient may be used; it is as useful in a one-legged man as a two- legged man ; and probably could be employed where the patient had lost the leg of the affected limb. It can be used in every case of suspected fracture of the femoral neck ; and it is not necessary that pressure should be made exactly over the top of the iliac spine or exactly over the edge of the inner malleolus. The two important points to be ob- served in this procedure are that the examiner should use forcible pres- sure over the two bony points, and that the patient's knee should be kept rigid. At the same time the assistant should make the utmost 38 justifiable traction downward and pressure upward during the manipu- lation. I at first thought that the relaxation visible in the tape indicated that the fracture was ununited, and that the sign would be of little or no value when there was impaction ; but from the inspection of ski- agraphs which seemed to show impaction, and where the relaxation of the tape was evident, I am led to think impaction does not lessen the value of the sign. It is surprising how little approximation (less than a quarter of an inch) of the points of pressure will show a marked sagging of the tape. In differentiating a fracture from a dislocation of the hip joint, I have had no experience in the use of the above sign. I imagine the same relaxation occurs as in a fracture; but the signs of each of these conditions are so different as not to give us trouble in differentiating them. At the bedside the question is almost always whether the patient is suffering from a fracture or not, and not whether he has a fracture or a dislocation. Taking up the question of the value of mensuration in the diagnosis of this fracture, it is common experience that two surgeons will not only differ in their measurement, but each one may obtain different results in his own measurements, even though he has the patient lying on a table and with the line of the body perfectly straight. The usual reason given for these differences is doubtless valid, that while the inner malleolus is easily made out, the anterior spine is not a spine, and it is difficult or sometimes impossible to be sure that one is pressing over the exact centre of it. More important still is the inequality of the limbs demonstrated by the late Dr. A. T. Bristow in a very careful set of measurements of the femora and humeri (Transac- tions of the American Surgical Association, Vol. XXVII. Page 429). These measurements confirm the conclusions arrived at by the late Dr. J. S. Wight from measurements in the living subject. These tables prove that an inequality, varying from 1-8 to i 3-8 inches may exist in the length of the lower extremities, the difference not depending on any previous lesion in the bones or limbs measured. This asymmetry demonstrated to exist in such a large percentage of persons (78 per cent in femoral lengths according to Bristow's figures) makes any con- clusions as to shortening in suspected fracture of the neck of the femur, based on measurements from the anterior superior illiac spine, a source of error. It is interesting, but not important, in this connection, to note the asymmetry that exists in other parts of the body — in the head as shown by comparing the two sides of hatters' patterns that are used in the custom-made silk hats ; in tailors' measurements for custom-made clothes ; in shoemakers' measurements for custom-made shoes ; and sometimes, though rarely, in comparing the two sides of a face or the length of fingers in the two hands. It is, however, very important, in using the anterior superior spine of the ilium in measuring the comparative length of the lower ex- tremities of a patient to ascertain if there is or is not an asymmetry in the pelvis similar to those mentioned above. It has been taken for granted that in using the anterior spine for measurements of this char- acter that symmetry of the pelvis exists in spite of the fact that de- formity of the pelvis is a subject that the obstetrician has been lecturing on for more years than the oldest of us have lived. This deformity is no doubt due in most cases to rachitic or other disease. But the other instances of asymmetry mentioned suggests that there may be a 39 pelvic asymmetry short of actual deformity that would make the an- terior superior spine of the ilium an unsafe point from which to meas- ure the comparative length of the lower extremities. Just here it may be mentioned that it is unsafe, when there is ap- parent shortening in suspected fracture to draw the limb downward sufficiently to have the malleoli on a line. The downward traction should be accompanied by actual measurement from some fixed point on the anterior spine, otherwise the apparent lengthening of the afifected limb may be due to tilting of the pelvis, unless counter ex- tension is used and both limbs drawn down with equal extension. To prove whether there is asymmetry of the normal pelvis, set a normal pelvis thoroughly cleansed of soft parts, on a flat surface, the pelvis resting on the point of the coccyx and the tuberosities of the ischium; lay a ruler across the anterior spines, and in a few cases the distance between the ruler and the surface on which the pelvis rests will differ on the two sides. Lack of ante-mortem knowledge of the history of the patient and a possible inequality of the tuberosities render uncertain any inference as to the asymmetry of the spine. A better method is furnished by cadavers in the dissecting room. Drive a pin into the top of the middle of the sternum through a tape measure in order to avoid any slipping of the tape, and measure the distance from this point to the anterior superior spines of the ilium (and this can be exactly located in a cadaver) ; and it will be found that the distance between the two points on the right and left side will differ in many cases. In one body that I measured it amounted to a half inch. Lack of knowledge of ante-mortem injury or disease, in spite of evi- dence to the contrary in the cadaver, holds here as well as in pelvic measurements. The best and most reliable evidence is furnished at the bedside, in living patients who can testify to any ailment or injury that might render the same measurements as in the cadaver uncertain. The anterior spine is more difficult to locate with exactness in the living person than in the cadaver, and one must be careful in the fixation of the upper end of the tape in the sternal notch, and also be careful to allow for differences produced by respiration. In spite of these causes of uncertainty, I found the measurements in forty patients confirmed the results of the cadaver measurements. In four cases the difference in the measurements was one-half inch (the maximum). It varied from this to equality in length. There is still a possibility that there may be an asymmetry in the malleoli of which I have no measurements to show whether it does or does not exist. With reference to the method of holding the upper end of the tape between the patient's teeth, it may be said that it im- plies the teeth to hold the tape, also a sterile tape before use, and a re- sterilization before employing it in the same way again. If mensura- tion is employed at all — and it certainly should be — I think with Dr. Bristow, "that the measurement taken from -the supra-sternal notch to the plane of the heel, as indicated by a plane surface in apposition therewith, will prove to be a method least open to error. The follow- ing precaution, however, must be adopted : The measurement must be made at the same period of respiration. The plane surface in ap- position with the heel must be parallel in each case, as a slight inclina- tion in either direction would mean an error in the measurements." The method employed in Dr. Bristow's bone measurements — a modified shoemaker's rule— would allow one to neglect the respiration as a cause of error. I have preferred, however, to use the "relaxation" 40 sign described above, as it enables one to neglect the respiration, asym- metry, mensuration, and even pelvic deformity in the diagnosis. Outward rotation of the foot is a well-known and often a striking symptom of fracture usually marked, sometimes excessive and at times absent. In a few cases inward rotation is present and difficult to ex- plain. Limitation of voluntary inward rotation of the outward rotated foot is also of some significance. This outward rotation of the foot gets its importance only as associated with other signs of fracture, for it is well known that it exists with contusion of the hip at times, and even when there is no question of fracture, as in general anaesthesia, in natural sleep, in debilitating disease, especially where the knee is even slightly flexed, and in the cadaver. I once saw it in an old lady suffer- ing from senile dementia who fell out of a low bed; the outward rota- tion was marked with no other signs of fracture except difficulty in standing for a few days. The rotation disappeared promptly, and after a few weeks the patient fell out of the other side of the bed producing a less marked outward rotation than on the other foot and with some lameness and with the same prompt recovery as before. The inability to lift the extended leg from the bed is a very marked symptom in almost all cases ; and some authorities have gone so far as to advise, even when other symptoms were absent, that such a patient should be treated as a case of fracture. I have seen certainly six cases where this symptom alone was present and a clear skiagraph has negatived the possibility of a fracture. One case recently was an elderly female who fell on her left hip and who presented this symptom of fracture alone. The skiagraph showed no fracture. At the same time the patient sitting on the edge of the bed had good though not quite normal power in extending the leg on the thigh and flexing the thigh on the abdomen. Another case with this symptom, beside out- ward rotation of the foot, shortening and the ability to have the limb lengthened by traction, and a positive skiagraph, after six weeks' treatment by Buck's extension, could lift the extended leg while the other symptoms of fracture were as evident as when she entered the hospital. This symptom is present in fracture of the patella; and I have seen it in acute synovitis of the knee joint, explained perhaps in this instance by the patient's timidity or fear of inflicting pain in any effort at lifting the limb. More importance should be attached to Hennequin's symptom than is usually done. The tenseness and swelling in the upper part of Scarpa's space, which is described as Hennequin's symptom, are quite characteristic of a fracture, and should be sought for in all cases. This sign is accompanied by the helpless look of the thigh if the foot is markedly rotated. In a few cases of very thin patients I have been confident that I could feel the deformity produced by the fracture by pressing deeply into the upper part of Scarpa's space, in spite of the increased tension. The so-called excursion of the trochanter is an unreliable sign at best, especially so if the patient is not under a general anaesthetic. Excursion of the anterior part of the foot with the patient anaesthetized, when the trochanter is seized between the fingers and thumb and forcibly lifted and depressed vertically, is of more value than the trochanteric excursion. Allis' symptom (relaxation of the fascia lata) has, theoretically, much to commend it, but personally I have not felt sure of its presence iniless there were more than the usual amount of shortening. I may make the same statement with regard 41 to use of Nelaton's line and Bryant's triangle, as I have had difficulty in being certain about the exact position of the top of the trochanter. Tenderness on pressure in the upper part of Scarpa's space, tenderness on pressure from behind forward at the suspected seat of fracture and pain complained of when a short stroke is made over the trochanter are signs usually present. Crepitus, false (or new) point of motion and deformity which are relied upon in diagnosticating fractures of the long bones are largely neglected in the diagnosis of the fracture under consideration, partly from an unreasonable fear of breaking up impaction by manipulating the limb to elicit crepitus and partly on account of the impossibility of recognizing the other two signs. The age of the patient is to be considered in fracture of the neck of the femur. A large proportion of these fractures occur in elderly persons with sometimes very slight injury ; and yet not a few fractures occur in the femoral neck of children although they are not disabled to the same extent as old persons. Let me in closing add one or two observations that seem not in- appropriate in this connection. With the exact knowledge furnished by a clear skiagraph the interne of a hospital, unless he is on his guard, will be tempted to neglect the search for the well established signs and symptoms on which reliance for so many years has been placed in making a diagnosis of fracture of the neck of the femur; and when he has finished his term of service, and gone into practice, and not having the facilities for the taking the skiagraph, he will feel keenly the lack of that aid and realize that he has been lax in the use of other and quite reliable methods of diagnosis. And on the other hand he will feel the unreliability of not a few of these signs that have been depended on in former years. For instance, a malingerer might sue another for causing a fracture of the neck of the femur and assume, as a result of injury, pain, inability to stand or flex the thigh, outward rotation of the foot, inability to lift the extended limb from the bed; and the surgeon might find a shortening of a half inch ; and if he could not find a deformity at the seat of fracture or a false or new point of motion and feared to examine for crepitus in the interest of the patient, and did not, or could not, confirm or correct his diagnosis by a ski- agraph, the patient would be treated for a fracture that did not exist and a jury might, within reason, render a verdict for damages to which the patient was not entitled. 42 V THE GERMAN HOSPITAL OF BROOKLYN. ECHINOCOCCUS CYST OF THE LEFT LOBE OF THE LIVER DISCHARGING INTO THE LEFT HEPATIC DUCT. Russell S. Fowler, M.D., F.A.C.S. Chief Surgeon, 1st Division, German Hospital of Brooklyn. Cases of echinococcus cyst involving the biliary passages upon which operation has been done are very rare. Cases have been re- ported by Duval, Langenbuch, Sasse, Lejeuntel (Alencon), Borchard (Bean), Page, Rossi, von Ruber, v. Mosetig-Moorhof, Korte and Kehr. Rupture of such cysts into the biliary passages is very uncommon. Rupture causes sudden blockage of the common duct and is the occasion of very severe biliary colic. There is profound collapse and death has been known to immediately follow. Frequently the block- age is diagnosed as calculus obstruction. A correct diagnosis is only possible if echinococcus elements are found in the stool. In some cases there have been reported recurring colicky attacks and inter- mittent common duct obstruction ; this occurs when the communication between the cyst and bile passages is small and closes from time to time. In other reported cases there were no colicky attacks but symp- toms of cholangitis. One fatal case presented the appearance of acute yellow atrophy of the liver. In cases in which the cyst does not present as tumor the differential diagnosis is between liver abscess, cholangitis with chronic stone or tumor blockage of the common duct; the diagnosis is only possible when cyst elements are recognized in the feces. Occasionally rupture occurs without symptoms ; then also the con- dition can only be recognized by the appearance of echinococcic ele- ments in the stools. In some cases there has been rupture into the veins of the liver or inferior vena cava followed by the carrying of embolic cyst elements to the heart and pulmonary arteries occasion- ing immediate death. The usual symptoms of rupture of an echino- coccic cyst into the biliary passages are severe pain, chills and fever. The obstruction in the common duct accompanying the rupture may be by impaction of cyst contents or by inflammatory swelling caused by the intense irritation. The case herewith presented gave the following history: N. R., female, age 21, married. No. 33205, seen in consultation with Dr. Calogero Giovinco Nov. 12, 191 5. About four months before the patient had noticed that her urine was high colored and she became jaundiced; after three days this jaundice disappeared. Two weeks ago she had pain in the epigastrium, diarrhea and vomiting. This pain continued and she vomiteid from time to time. Examination showed the abdomen extremely tender below the right costal border and over the right lobe of the liver. There was rigidity of the right rectus muscle. Moderate jaundice. 45 Immediate operation was done. The liver was found enlarged and acutely congested; the edges rounded. Intense inflammation of gall bladder and ducts with all the glands along the cystic, hepatic and common ducts acutely enlarged. Locally intense peritonitis. Gall bladder opened and found packed with fine brilliant yellow sand. Walls thickened and acutely inflamed. Gall bladder cleansed. Chole- cystostomy. Two split tube drains. It was not thought wise to ex- plore the ducts on account of the extreme and unusual acute inflam- mation. It was thought in all probability the same yellow sand would be found throughout the ducts and that it would be impossible to cleanse the ducts with the existing inflammation. After course: The jaundice slowly subsided Dut never entirely disappeared, a little yellow tinge persisting in the eyes. Pain sub- sided. Bile flowed from the tube and appeared in the feces. It was deemed advisable to continue gall bladder drainage for a consider- able period but unfortunately the tube became displaced on the tenth day and this fact was not discovered until the day following. An attempt to replace the tube was unsuccessful. The patient continued free from pain except slight epigastric cramps from time to time; gradually gained strength though a slight degree of jaundice per- sisted. The wound healed slowly. There was but slight discharge of bile from the wound. Dec. 8, 191 5. Discharged. Wound healed. Very slight jaundice. Dec. 22. Severe epigastric cramps and slight increase in jaundice. Deo. 26. More severe cramps and pain over the gall bladder and liver. Readmitted to hospital. Slight jaundice. Liver enlarged, two fingers breadth below free border of ribs. Gall bladder region sensitive. Wound firmly healed. Operation was delayed on account of the difficulty which it was felt would be experienced in cleansing the ducts. However, pain increased and jaundice deepened slightly so that operation could no longer be delayed. Operation. Jan. 6, 1916. Incision through previous scar. Many dense adhesions. Gall bladder adherent to scar; acutely distended; opened. Contents, thin bile ; mucous membrane intensely congested ; hour glass type of gall bladder. Colon, omentum, duodenum, liver and stomach densely adherent to gall bladder and neighborhood. Adhesions separated carefully and normal anatomical relationship of parts restored. Cystic duct dilated to twice normal. Common duct dilated to the size of the duodenum or even larger. Bile aspirated from common duct by suction apparatus. Duct incised, walls two to three times normal thickness ; escape of bile and bile stained mem- branous detritus. This membranous detritus varied in size from pin point to the size of the last joint of the ring finger. Metal catheter in- troduced into common duct and duct washed out with saline, the opening into the duct having been enlarged sufficiently to permit of the ready escape of the saline alongside the catheter. Over a pint of detritus, stringy, glutinous, stained black with bile, was washed out in this manner or removed by a long curved blunt curet introduced for several inches, ten inches at times, into what was taken to be the left hepatic duct. In the detritus were numerous pieces of thick green membrane, recognizable as probable echinococcus cyst lining. Two gallons of saline were used. A large probe passed freely into the dun- denum. Some saline, about a pint in all, was allowed to run into the duo- denum from time to time. When the saline from the duct returned 46 clear the curet was passed up and fresh membrane removed and the flow again started. This was repeated until so far as could be as- certained the ducts were clean. The curet passed ten inches into the left hepatic duct without meeting resistance. There was no bleeding from the irrigation. Digital exploration revealed a large opening of the common bile duct into the duodenum, an opening large enough to admit the tip of the finger into the duodenum; the common duct itself was enormous, the finger was lost in it ; toward the liver the finger felt an opening about twice the normal size, taken to be the right hepatic duct opening and a continuation of the common duct taken to be the left hepatic duct which freely admitted the finger. The latter was fully as large as the enlarged common duct, the size of the duodenum (Fig. i.) The cystic duct opening could be demonstrated and was twice the normal size. The lining of the common duct and the left hepatic duct was smooth. The lining of the common duct so far as could be seen presented no evidence of inflammation. The patient was thin, worn out by long illness and bore the operation very badly. The pulse, while the beats were distinct, was extremely rapid, rising to over 200 per minute during the irrigation of the hepatic duct. It was felt, however, that the patient stood very little chance of recovery unless this duct could be freed entirely of its impacted detritus. When the ducts were apparently clean and the irrigation discontinued, the pulse fell to 180 but of very poor quality. Continuous hypodermic whiskey stimulation was given from the time the pulse became weak and saline and whiskey were administered by rectum. A rubber tube, with a fenestrum cut in the side was placed in the left hepatic duct through the common duct incision in such a manner as to place the fenestrum facing toward the duodenum. This was used to take the place of a T tube which was not available. A large calibre tube was used not only for the purpose of freer drainage and to avoid block- age but also with the idea of allowing of irrigation of the hepatic duct and common duct should blockage occur, or should some of the detritus show in the discharge from the tube. The incision in the duct was sutured around and to the tube. A split tube was placed in the foramen of Winslow ; a second split tube in relation to the junction of the cystic duct with the common duct (which juncture was higher than usual) ; a rubber tube was placed in the gall bladder and the gall bladder edge inverted. The condition of the patient did not allow of cholecystectomy although otherwise this was indicated. A rapid layer closure of the abdomen was effected. The patient left the table with a pulse of 180, very weak. After-course: General treatment of shock (heat, posture and saline by rectum) in addition to direct cardiac stimulation with half strength whiskey by hypodermic, continuous at first, then every two minutes, later every five minutes and so gradually stopped, succeeded in accomplishing restoration to a fairly good condition in twelve hours; at the end of twenty-four hours the bed was leveled and the patient out of danger so far as the operative procedure was concerned. The jaundice was less marked. At no time had it been severe. For the first forty-eight hours the discharge through the duct tube con- nected with a subaqueous drain was free and consisted of clear bile. Jan. 8, 1916. Detritus began to pass through the duct tube and it was feared that blockage might take place. Eight ounces of saline were slowly introduced into the common duct, the subaqueous drain 47 being also disconnected and cleaned. The introduction of saline pro- duced no pain. The patient noticed a sensation of warmth in the epigastrium. There was a return of about one ounce of saline through the gall bladder tube. The return flow through the duct tube con- tained mucus and thick stringy material, blood streaked. About two ounces of the saline was not returned. Following this flushing of the common and hepatic ducts the discharge from the duct tube again became free and clear bile. As much as ten ounces of bile was col- lected in the bottle in twelve hours. Jan. 9, 1916. The flushing was repeated there having appeared some detritus in the discharge. This detritus consisted of echino- coccus cyst lining. At this irrigation seven ounces of saline was used, two ounces at a time being slowly introduced and then a wait of a few minutes. The return flow again contained mucus and thick, stringy reddish material. About two ounces of saline returned through the gall bladder tube. Practically all of the saline returned. The patient complained of slight pain during the irrigation. Jan. 10. The common duct was irrigated, seven ounces of saline being used. Return flow as before ; two ounces were returned through the gall bladder tube. Practically all the saline returned. Jan. II. Common duct irrigated; return flow about the same; some saline, about two ounces, returned through the gall bladder tube. Patient noticed scarcely any pain. A small amount of saline escaped through the wound alongside the tubes. Jan. 12. Return flow the same. Saline returned through the gall bladder tube and a considerable amount escaped through the wound alongside the tubes. This irrigation occasioned no pain. Jan. 13. Sutures removed ; good wound union except at emer- gence of tubes. Split tube removed. From this time on the patient was comfortable. Free biliary drainage continued from the gall bladder tube and from the duct tube. The tubes were removed on the seventeenth day. Further convales- cence uneventful. The wound discharged a good quality of bile and the stools became normal. Feb. 5. Discharged. Wound reduced to a small sinus. No biliary discharge. Patient strong. Pathological Examination : The detritus removed at operation showed everywhere echinococcus cyst wall and hooldets. No daughter cysts could be demonstrated. Examination of the detritus passed through the common duct tube post-operatively showed characteristic booklets. Repeated examination of the stools failed to show echino- coccus elements. Feb. 23. Wound firmly healed. Patient has remained free from symptoms and is rapidly regaining her strength. May 21. Patient has remained well. 48 EXTENSIVE AND RECURRENT CARCINOMA OF THE BREAST AXILLA, NECK AND THORAX. James Peter Warbasse, M.D., CASES of carcinoma of the breast, which have or have not been operated upon, which show symptoms of extension along the course of the axillary vessels and nerves, giving rise to swelling, pain, and numbness in the arm, have customarily been regarded as in- operable, and condemned to morphine, x-rays, serums, bacterins, or quackery until the inevitable end. The suffering of these patients is very great, and death is welcomed as a rehef. Has surgery nothing to offer these unfortunates? I think it has. The mistake made by the older surgeons has been to think of carcinoma of the breast as carcinoma of the breast, when as a matter of fact it soon is carcinoma of the axilla, neck, and thorax, and should be thought of from the beginning, either in fact or potentially, as such. In these desperate cases the surgeon must put out of his mind the idea that he is considering a disease of the breast, lest the psychol- ogy of timidity be stimulated by the observation of the great distance from its origin which the disease has traversed. When vs^e think of disease of the axillary vessels, brachial plexus, scapula, humerus, clavi- cle, lymphatics of the neck, ribs, pleurae or lungs, we are aware that any of these structures may be removed, and are every day being attacked with impunity by surgery. Primary cancer of these struc- tures is unhesitatingly extirpated. Why should the surgeon withhold his skill from such disease, if perchance it were preceded by a can- cer of the breast? These patients can be made more comJortable, and life in a cer- tain number prolonged, and in some the disease cured by such radi- cal operations. I have no hesitation in saying that such operations have more to offer and will show more cures, than the simple am- putation of the breast for primary carcinoma which was commonly practiced thirty or forty years ago. When the disease involves the axillary vessels and nerves and has palsied the arm, the operation begins with amputation of the shoulder. A flap is made from such tissues as are farthest from the disease. The scapula and clavicle should be removed without hesitation in order to remove disease or to uncover the vessels and nerves which are involved. The axillary and sub-clavian vessels should be followed up into the neck and thorax, and the vessels together with all surrounding tissues removed. This dissection and excision may be carried as far as is necessary to reach the limit of the disease. At the same time the cords of the brachial plexus should be followed up and removed with their surrounding tissues. Before cutting the nerve-trunks they should be injected with novocain to block impulses and prevent shock. 49 This dissection and excision of vessels and nerves may be carried as far as is necessary. If it is discovered that a rib or ribs are in- volved in the disease, they may be removed. Ribs are removed for other conditions; why not to save a patient from cancer? Involve- ment of the pleura calls for resection. Involvement of the lung de- mands removal at least of the affected lobe. A lobe or the whole lung is excised for other disease, why not for carcinoma . There is no structure in the side of the neck which may not be sacrificed. Vessels, including the internal juglar and carotids, may be resected. The brachial plexus, vagus, and phrenic nerves may all be removed. In the chest the only structures which must be preserved on one side are the heart, aorta, and vena cava. The whole of one lung, the ribs which cover it, clavicle, scapula, arm, all the vessels and nerves of one side of the neck, and the neighboring and involved connective tissue, muscles, and lymphatics may be extirpated. This means that everything, practically on one or the other side of the spinal column from the base of the skull to the diaphragm may be removed (Figs, i and 2). No operation, of course, would involve all of these structures; can- cer would not involve them all. They are enumerated, however, to show the possibilities of radical operations. Such procedures should be carried out with due regard for the possibilities of shock. Blood should be saved; and nerve trunks should be desensitized. Operations of this sort may be done in several stages, with intervals of several days for recuperation. In the hands of the experienced surgeon who knows how to save blood and minimize shock, these operations have much to offer. The experience of surgeons is showing that many patients, other- wise doomed to a painful exodus, may be made comfortable, may have life prolonged, or may be cured by such radical procedures. The literature of surgery is growing rich in the reports of these triumphs. Presumedly hopeless cases have been cured. Many cases have been operated upon repeatedly for recurrences and life prolonged, or the disease ultimately cured. No patient should be regarded as beyond the hope of relief unless the general toxemia and inanition indicate an early conclusion. 50 ™ nS EPITHELIOMA OF NOSE. James Peter Warbasse, M.D. THIS patient, a man now seventy-two years of age, was operated upon by me twenty-two years ago for epithelioma of the nose. At the place where the nose-clip of his eye-glasses pressed against the skin on the side of the nose, an indurated area had de- veloped. Discontinuation of the pressure by changing the position of the clip and modifying the character of the glasses was not followed by healing. The area was small, and the induration but slight, still the suspicion of epithelioma was sufi&cient to call for its removal. Ac- cordingly, under cocaine anaesthesia, an eliptical incision was made about the area of the disease, which was removed, together with a small zone of apparently normal skin around it. As large a wound was made as could be closed by simple suturing. The closure of the wound was accomplished by interrupted silk sutures. The removed piece was subjected to microscopic examination by Dr. Eugene Hodenpyle and Professor T. Mitchell Prudden, of the College of Physicians and Sur- geons, New York, both of whom reported that the growth was epi- thelioma. Most probably enough tissue had been removed to eradi- cate the growth. The incision had been placed about 2 m. m. away from the apparent disease. Still the operation had been done for two pur- poses: (i) diagnosis and (2) therapy. Had a positive diagnosis of epithelioma been made before the operation, the therapy would have been expressed in a wider operation. Plastic on Nose (a) The lines of skin incision. (b) Tumor ex- cised and wounds sutured The diagnosis now being at hand, it was determined to apply the therapeutic measure of choice. The wound had healed and the sutures had been removed. Under local cocaine anaesthesia, the scar of the first operation and the skin about it for a distance of 4 m. m. were ex- cised by an elliptical incision. This left a wound too large to close by simple apposition sutures. A curved incision was carried from either end of the elliptical wound, marking out a flap on either side, the length of the wound, and having a width at their bases equal to the widest width of the wound (Fig. i). One of the lateral flaps was made by carrying the incision to the median line of the nose, the other by carrying the incision to the inner canthus of the eye. These flaps were dissected free, and united in a straight line over the denuded area. The two lateral wounds were then closed by in- terrupted sutures. Fine interrupted silk sutures were used (Fig. 2). Primary healing followed. Now after twenty-two years the patient is here free from any suggestion of disease, and with a scarcely discernible scar. It is ob- served that he still, as a matter of precaution and habit, wears his glasses low down on the nose, thus giving expression to the surgical sense which prompts avoidance of further irritation of a once vulner- able area. 51 ON IMPENDING PERFORATION OF GASTRIC AND DUODENAL ULCERS. Carl Fulda, M.D. IT must have been noted, even by those only superficially acquainted with the Hterature of perforated gastric duodenal ulcers, that the mortality in this class of cases is higher than it should be in view of the advances made in other acute abdominal conditions. A mortality of 73 per cent ^ or even of 40 per cent - does not compare favorably with the death rate of appendicitis or cholecystitis. And yet these latter conditions frequently present, at operation at least, far greater technical difficulties than do those cases now under dis- cussion. Aside from those determining factors, as age and general condi- tion of the patient, which are common to all surgical procedures, there are two which decide what shall be the issue, once a perforation has taken place. They are : 1. The age of the perforation. 2. The operation performed. Considering the second factor first, we find that it has received the greater attention. We will grant at once that a decided difference in the outcome is to be noted between those cases in which closure could be performed and those in which closure could not be done.^'^ Failure to close the ulcer may be due to inability to find the perfora- tion, to technical difiiculties presented by extensive induration, or by its position. This is admitted even by the most skillful and "from the char- acter of the condition and its urgency it must happen that these cases will be operated upon by those not of long experience in emergency abdominal operations." ^ Petren's table shows, that while 9 per cent were saved where suture could not be done, that even where closure was possible there was still a mortality of 46 per cent. The most attention has been given to the question as to whether or not a gastro-enterostomy should be added to the closure. The sugges- tion of von Eiselsberg to perform jejunostomy in certain cases of this type, has only very rarely been followed, in this country at least. As to gastro-jejunostomy, it is advocated: (i) When the infolding of large indurated ulcers has resulted in obstruction at the pylorus; (2) for the reason that closure alone does not cure the ulcer or a second ulcer present; (3) it is maintained that closure does nothing to pre- vent subsequent ulcer formation ; and finally (4) because gastro- enterostomy will, in addition to its other advantages, allow earlier feeding and laxative medication. ° As to the question of obstruction, it will be acknowledged that it is difficult to obstruct the pylorus unless elaborate operative pro- cedures are undertaken. ^-^ \\'"e have never seen it occur even where the infolding was very extensive. As to late results, such as obstruction and cicatricial distortion, it has been shown that this does not occur.''' In regard to the second point of advantage, enough cases have been reported to show that within a short time after perforation and 52 Fig. 1. Chronic nicer of stomach. Microscopic section from Case 11. All layers except serosa are destroyed and perforation is imminent. Fig. 2. Removed pylorus from Case II, with portion of stomach and duo- denum. Mucosa aspect ulcer directly at pylorus about to perforate. closure, the ulcers have healed absolutely. As objection to the third advantage, that of preventing subsequent occurrence of ulcers, enough evidence has been presented to show that subsequent ulcers do occur.2'8'^ Lastly, these patients can be fed as early without gastro- enterostomy as with it ; and as to the administration of laxatives, that will not generally be accepted as desirable. We object to the performance of gastro-enterostomy in these cases of perforation because we are not convinced that it is a safe procedure in the presence of a peritonitis. Granted that the infection is of a low grade, it must also be allowed then that the escape of an acid gastric contents has lowered the resistance of the peritoneum. Further, its performance must add to the length of time of operation and so to the shock of the perforation in a patient whose resistance is low from prolonged gastric disturbance and who still has to look forward to a struggle with a peritonitis. We have never performed a gastro-enterostomy in "five or at the outside seven minutes." ^ Thirty-five to forty minutes, the time stated by Eliot ^ is more nearly like the length of time required by most operators. The danger of a jejunal ulcer following gastro-enterostomy, though slight, must be added to the total of evidence against it. When we consider the question of cancer formation on an ulcer base ^^ excision would be of greater value than gastro-enterostomy. More important, however, than all this, is the fact that it has not been shown that adding gastro-enterostomy to closure of the ulcer has in the slightest degree lowered the mortality of perforated gastric or duodenal ulcer. Its advocates claim for it some value in the patient's future; but the present events in his life are those with which we are most concerned. If there were no other valid reasons against its being done, it should be omitted for the reason that it adds nothing to the chances of recovery. Of vastly greater importance is the question of the time of operation. On this point there is, and can be, no dispute. The longer the interval between perforation and operation, the higher is the mortality; the further the peritonitis has advanced, the less is the chance of recovery. Perhaps because it is generally accepted, little has been said on this point in comparison with the amount of discussion on "gastro- enterostomy or not." Now, one might suppose that from the ability to recognize a perforation early to the ability to recognize a threat- ened perforation would be a natural progression of events. And yet, with one or two exceptions, nothing has been said on this point. We beheve that the important reduction in the mortality of these cases will come when an imminent perforation is recognized, and the necessary surgical steps taken ; and not before that time. It must be remembered that early recognition and operation of a perforation, though important, are not alone sufficient. Similar symptoms, of a perforated ulcer, may accompany vastly different pathologic conditions, as discovered at operation. In one case the perforation may be small with little leakage. In others there may be a wide opening with the escape of large quantities of gastric juice and even an entire meal. So that, even if operated upon early after prompt recognition, there will still be factors present beyond our control and variable in determining the end results. Again, these acute abdominal conditions do not always occur when time and place are convenient for patient and operator. As a matter of fact it is doubtful whether the exact time of 53 perforation is ever recognized. In the great majority of cases it is the spreading of the peritonitis that produces the alarming symptoms. The erosion has gone on slowly, approaching the serosa little by little. The inflammatory process spreads to the peritoneum which thickens in its attempt to prevent the perforation. The threatened point is further protected by omentum, sometimes by the under surface of the liver, by spleen, or even by the anterior abdominal wall. As the erosion goes on, one of several events may happen. Either the de- structive process goes on faster than the protective process without, or the force within the stomach may become too great, and there results more or less profuse leakage, and a rapidly spreading periton- itis. It is not denied that there are cases in which little or no effort at a protective process can be seen, but in the greater number of cases the sequence of events occurs as described. Epigastric pain and epigastric tenderness are the most important symptoms of impending perforation of gastric or duodenal ulcer. Other symptoms of ulcer may or may not be present, or have been present. The pain varies in severity a good deal with the patient's temperament, but it is decidedly epigastric, and, if present in the patient's past history, increased markedly. The tenderness is severe and localized, the maximum point thereof corresponding to the site of the ulcer. Rigidity of the abdominal wall, though present, is of a lesser degree than when the peritonitis is well under way. It is true that these, symptoms are present in most cases of ulcers, but it is their increase, their comparison with previous conditions that is important. It must not be forgotten that chemical, thermal and mechanical stimuli are felt only in the upper and lower ends of the alimentary tract. They are lost in the upper esophagus, and only perceived in the lower rectum. Ulcerative processes in the stomach and duo- denum do not in themselves cause pain except when the inflamma- tory condition extends to the neighboring peritoneum. According to the direction in which the lymphatics carry the inflammation, the pain, by irritation of the lumbar and intercostal nerves, may be re- ferred to organs that also send lymphatics to these nerves. ^^ These anatomic relations explain the frequency with which less acute ulcer- ative conditions in the stomach and duodenum are confused with lesions of the gall-bladder, kidney, appendix or pancreas. ^^ Increased epigastric pain and increased epigastric tenderness then, in cases with a history of gastric or duodenal ulcer, are to be interpreted as meaning that the peritoneum over the lesion is taking part in the inflammatory process. Whether or not the necrosis also will extend to the serosa, that too, is beyond our control. The im- portant fact is that the perforation is imminent and prompt surgi- cal interference is indicated. Brentano^ obser\^ed that cases of perforated gastric and duo- denal ulcer gave in their histories prehminary symptoms of perfora- tion, such as cramps and stabbing pains and called them "Heralds (Vorboten) of perforation." MitchelP^ observed that rigidity and tenderness are signs that the peritoneum is already involved, and are danger signals of perforation. McGuire^* noted an increase in pain and tenderness just before perforation. Noetzel^^ hoped that the mortality of the perforated cases would be reduced by prophylactic means, that is, by early operation of painful ulcers. That is what 54 Fig. 3. Removed pylorus with portion of stomach and duodenum, tense inflammation of peritoneum. Perforation imminent. In- FiG. 4. Removed pylorus. Mucosa side of Fig. 3, showing part of stomach and duodenum, ulcer about to perforate. Second ulcer is seen. we wish to emphasize and indorse, operation before, not after, per- foration. In the following seven cases the diagnosis of impending perfora- tion was made and operation urged. Case I refused operation for the reason that several months before, he had recovered from a similar attack under medical treatment. His refusal was given in much the same manner that patients with appendicitis, in their second or third attack, beg for another trial of the ice-bag. And this we point out as an objection to the medical treatment of painful ulcers, that if the patient recovers for the time, as they do, in later attacks much valu- able time may be lost trying the same treatment again. As a further objection to this plan of treatment we may add that many of these cases, for economic reasons can ill afford to undergo these long terms of rest. They must be returned to work as promptly as possible. ^^ Case I. — German Hospital. No. 31546. O. B. 27. Admitted to hospital April 24, 1915- History of stomach trouble for several years. Pain and epigastric tenderness. Worse two months ago. Recovered under care of physician, rest in bed, milk diet, etc. On readmission, symptoms again worse for several days. Operation advised by physician and refused. Twelve hoiurs after admission symptoms alarming. Operation April 24, 1915. Large indu- rated ulcer high up on lesser ctuvatiu-e. Considerable free blood in epi- gastrium. Perforation only made out by noting point of escape of gastric con- tents. Infolding with one deep suture and gauze tampon. In this case the perforation took place while the patient was in bed in a hospital. Recovery uneventful, discharged thirty-ninth day after operation. Case II. — German Hospital. No. 3031 1. L. I/. 49. History of stomach trouble for years. Periodic pain, vomiting and epigastric tenderness. Food increases pain. Recently all symptoms worse. Retracts epigastrimn in walking. Tenderness in epigastrimn over area midway between umbilicus and ensiform. Diagnosis, impending perforation of gastric ulcer. Operation November 12, 1 9 14. Large indiu-ated ulcer on lesser curvature. Peritonemn red and thick over lesion. ]Bxcission of ulcer and posterior gastroenterostomy. Recovery uneventful. Discharged twenty-first day after operation. From the illustration (Fig. i.) it will be seen that only the thinnest layer of tissue separates the stomach and peritoneal cavities. There is little doubt in our mind as to the probability of perforation in this case. Case III. — German Hospital. No. 30903. W. D. 22. Attacks of pain in stomach for two years, lasting weeks at a time. Pain came on soon after eat- ing. Present attack began three weeks before admission. Artificial vomit- ing brings relief. Entire epigastrimn tender, most marked to right of point half way between umbilicus and ensiform. Operation, February 5, 1915. Ulcer, indurated, of anterior siuface of stomach near pylorus. Peritonetmi red and thickened. Posterior gastroenterostomy. Recovery imeventful, discharged nine- teenth day after operation. In this case gastroenterostomy was deemed sufl&cient. The man has been well since. Case IV. — German Hospital. No. 33090. H. P. 48. Had stomach trouble for five years. Sharp pains in epigastrimn radiating to back. At first twice a year, attacks are now once a month and more severe Ln character. Artificial vomit- ing brings relief. Four days before admission pain is continuous. Eat- ing does not influence pain! Diagnosis, Impending perforation of gastric ulcer. Operation, November 11, 1915. Ulcer high up on lesser curvature, adherent behind and boimd down. Much induration. Peritonemn thickened and red. 55 Posterior gastroenterostomy. Discharged cured twenty-seventh day after operation. As in Case III, gastroenterostomy was sufficient to bring about a cure. Patient has been free from pain since. Case V. — German Hospital. No. 33257. C. G. 34. One week before ad- mission patient had pain in epigastritim, stabbing in character, vomited blood. Pain relieved by eating! Had tarrystools. Kpigastrium rigid and very tender over area to right of point half way between umbilicus and ensiform. Diag- nosis, impending perforation of ulcer at pylorus. Operation November 22, 1915. Large induration of duodenvmi pylorus and pyloric part of stomach. Peritoneum very red and ulcer can plainly be felt, especially its thin base. Resection of pylorus and indurated area either side thereof. Posterior gastro- enterostomy. Discharged on thirty-second day, cured. Aside from the extensive induration the case presented the inter- esting feature of a second ulcer on the gastric side of the pylorus (Fig. II.). On searching for this patient to ascertain his present con- dition we learned that he had contracted pulmonary tuberculosis and had gone to some country sanitarium for treatment. Case VI. — German Hospital. No. 33278. F. S. 38. Four years history of stomach trouble. Boring pain in epigastrium. Food aggravated pain! Vomited no blood. Pain severe for last year. Starved on account of fear of food. Even milk caused excruciating pain. Same pain day and night. Entire epigastrium very tender but not rigid. Diagnosis, ulcer at or near pylorus. Operation November 23, 1915. Entire pylorus for 2.5 cm. (i inch), both ways red, indurated and hard. Ulcer felt in pylorus with thin base. Under surface of liver adherent over ulcer but easily freed. Resection of pylorus and posterior gastroenterostomy. Discharged one hundred and sixty- ninth day after operation. (Figs. Ill and IV.) It will be noted that in this case also, a second ulcer was found. The peritoneum was intensely inflamed and the ulcer base thin. On the twenty-eighth day after operation a gastric fistula appeared which failed to close until the hundred sixty-ninth day after opera- tion. Case VII. — German Hospital. No. 34408. P. S. 25 Denies any previous history of gastric disturbance. About an hour before admission he experienced sudden epigastric pain. Epigastrium is tender and rigid. Maximum point of tenderness over duodenum. Diagnosis, impending perforation of duodenal ulcer. Operation March 30, 1916. One and one-half hours after admission pylorus and first part of duodenum adherent to anterior abdominal wall. Only very slight leakage from ulcer at pylorus which may have been started by separating gut from abdominal wall. Entire pyloric portion of stomach, pylorus and first part of duodenum indurated. Adhesions freed and ulcer found in pylorus with base the size of a dime. Whole indurated area infolded without regard to occlusion of pylorus. Gauze strip to point of infolding. Discharged seventy-nineth day after operation, cured. Dismissal in this case was delayed by a suppurative parotitis and by repeated x-ray examinations. The last report made May 22, 1916, six weeks after operation, is : Plate of stomach shows good tone, regular peristalic wave and perfectly normal contour (Report Num- ber 406). On the fifth day this patient was taking all the fluids he wanted and in the twenty-seventh day was eating regular mixed diet. He vomited only once, an hour after operation. This case is added because, though there was infolding of a greater amount of gut wall than usual, there was no ill effects noted and six weeks after opera- tion no distortion of the stomach was observed. It must be noted here, that the infolding is done in the long axis of the stomach and duodenum which probably occludes less than if the folds were made across the gut, 56 Tabi,e I. Durati®n Tender- No. I 2 3 4 5 6 7 In Vomit- Pain ing + + o + Rel. of Food to Pain worse worse worse none relief worse Age Loc. of Sym. ness 2^ Gast. 2 years 4- 49 Gast. 5 years -}-+ + 22 Gast. 5 years + + Induced 43 Gast. 5 years + + Induced 34 Duod. 1 week -f- ++ + 38 Duod. 4 years ++ ++ + 25 Duod. o + + + _ — the table given, the symptoms are arranged in the order of their value to us. It will be noted that those considered most import- ant are also the most constant. It may be added that the same relative value is placed on these symptoms in dealing with less acute ulcers or ulcers already perforated. In conclusion we may state that gastroenterostomy, of whatever value in other types of ulcers, does not, when added to closure of a perforated gastric or duodenal ulcer, improve the patient's chances of recovery. Though early recognition and operation have given the best results, we submit, nevertheless, that the hope for improvement in the situation Hes in operation before perforation. REFERENCES. 1. Brentano, Langenbeck's Archiv. Bd. 81, No. i. 2. Petren, Surg. Gyn. & Obst. Vol. XIV, p. 555. 3. Eliot, E. Annals of Surgery. Vol. LV, p. 557. 4. von Eiselberg, Deutsche Med. Wchnschft. 1906, No. 30. 5. Patterson, Surgery of the Stomach, p. 170. 6. Lewisohn, Surg. Gyn. & Obst. Vol. XXII, p. 379. 7. Gibson, Surg. Gyn. & Obst. Vol. XXII, p. 388. 8. Jaboulay, Archiv. Prov. de Chir. 1906, No. 9. 9. Cuff, Brit. Med. Journal. 1907, Feb. 2. 10. MacCarty, W. C, Surg. Gyn. & Obst. 1910, p. 447. 11. Seyffarth, Deutsche Med. Wchnschft. 1911, p. 731. 12. Lennander, Centralbl. f. Chir. 1901. 13. Mitchell, Annals of Surgery. 1911, Dec. 14. McGuire, E., Buffalo Med. Journal.^ Vol. 67, No. 11. 15. Noetzel, von Bruns Beitr. z. Kl. Chir. Bd. 51, No. 2. 16. Schwarz, Centralbl. f. Chir. 1912, p. 26. 57 VI THE JEWISH HOSPITAL OF BROOKLYN. CLINIC AT THE JEWISH HOSPITAL. William Linder, M.D. SPLENECTOMY FOR TUBERCULOSIS OF SPLEEN. Case; I. The patient is a woman twenty-nine years of age, who for three years has been suffering from symptoms referred to her stomach. She has lost twenty pounds in weight and is the subject of progressive weakness. She is the mother of three children, of whom the youngest is one year of age. She was admitted to the hospital on March 27, 1916, complaining of a lump in the left side of her abdomen, which was not painful or tender, she is the subject of occasional chilly feelings. Examination shows an emaciated woman, with clear conjunc- tivae, no petechia, no enlargement of glands, with diffuse signs of tuberculosis in both lungs. The left half of the abdomen is promi- nent. There is a marked diastasis of the recti muscles. The promi- nence of the abdomen is due to an enlargement of the spleen which by percussion is found to extend from the ninth rib above to the brim of the pelvis below. The liver is enlarged and extends from the fifth costal interspace above to i inch below the umbilicus. Blood : hemoglobin 57 per cent; R.B.C. 3,520,000; W.B.C. 4,200; Polys. 66 per cent ; slight poikilocytosis and anisocytosis. Wassermann negative. Urine normal except presence of some colon bacilli. Temperature upon admission, for the first three days varied from 100 to 102, then sank to from 99 to 100. Pulse from 100 to 120. Respiration 24. Remarks upon the diagnosis : The hemolytic function of the spleen has been determined by experimentation in Banti's disease when we find excessive hemolysis occurring. The removal of the spleen in the early stages of Banti's disease is attended by great benefit, before secondary cirrhosis of the liver with its associated jaundice, ascites and gastro-intestinal hemorrhages occur. In this connection the Gaucher type of splenomegaly must be considered for purpose of differentiating. The Gaucher spleen occasionally runs in families, has no associated cirrhosis of the liver, no hemorrhages, no jaundice, no ascites. In this particular case the blood picture, the leukopenia, the secondary anemia, the associated enlargement of the liver and the absence of any glandular enlargement suggests Banti's disease. On the other hand, the possibility of tuberculosis of the spleen must not be overlooked. Miliary tuberculosis of the spleen usually produce only a moderate enlargement. The largest spleen recorded with tuberculosis is the amyloid which accompanies chronic ulcerative phthisis. In this case the diffuse lung signs together with the X-ray findings, the dyspepsia, the temperature that subsided with rest bespeaks a possible tuberculosis. In either event a spleen, such as this, is a menace to the continued life and well-being of the patient, was made on the left side extending from the ninth costochondral and indication for removal is clear. Ether was then administered by Dr. I. D. Kruskal. An incision junction to the outer third of Poupart's ligament along the outer side 61 of the left rectus muscle. The peritoneum having been opened and the spleen exposed, it was found to have a very short pedicle with several large bands of adhesions attaching it to the diaphragm. A better exposure was now obtained by dividing the eighth and ninth costal cartilages and fracturing the corresponding ribs making an osteo-plastic flap, which when retracted brought the diaphragm and upper pole of the spleen into clear view. The esophagus going into the stomach was plainly seen. The operator remarked that an ulcer of the cardiac end of the stomach could be removed with ease by this method of exposure. He stated that he had done a complete gas- trectomy using this incision with the recovery of the patient. The diaphragmatic adhesions were doubly ligated and divided between the ligatures. Only the upper pole of the spleen was freed. The gastro- splenic pedicle was then exposed and divided between ligatures until the entire blood supply of the spleen was controlled. This was ac- complished without disturbing the spleen from its bed. The spleen was then lifted from its bed; inspection of the wound showed com- plete hemostasis. The abdominal wound was then sutured in layers and closed without drainage. Pathological report of specimen: gross weight 1,266 grams; size 26 by 14 by 7 cm. Capsule very thick, marked increase in consistency of parenchyma. Surface granular pinkish with areas here and there of bluish colored tissue. Tendency to fasicular arrangement of por- tion of the splenic pulp. Many blood vessels with patent mouths. Microscopic section showed tuberculosis of the spleen. CYSTIC GOITRE; THYROIDECTOMY. Cass II. The patient was a girl twenty-three years of age who had been the subject of a small swelling of the neck, noticeable for ten years. Six years ago it began to increase in size and has become steadily larger until the present time. Now there is a large swelling occupying the left side of the neck and extending from the left angle of the jaw to one and one-half inches to the right of the median line, and from the clavicle to the lower edge of the jaw. The patient suffers from cardiac palpitation only after much exertion, there is slight exopthalmia. Face is flushed; tonsils not enlarged. Blood count: W.B.C. 13,200; polymorphonuclears 81 per cent; monoculears and transitional i per cent; lymphocytes 18 per cent. Pulse from 72 to 88; temperature normal. Dr. Linder remarked that this patient has as yet manifested but slight symptoms of thyroid toxemia from a result of increased thyroid secretions, although she is very excitable. Her real motive for applying for operation is on account of the dis- figurement from the growth and some pressure symptoms. She has a simple cystic goitre, but such a goitre can produce secondary hyper- thyroidism, by pressure upon that part of the thyroid which is still active and so stimulating increased production of secretion. It may easily be converted into a simple goitre of the Basedow's type. In the removal of a goitre of this kind special care is to be observed to avoid removal of the parathyroid bodies producing myxedema. The patient was then anesthetised by ether oxygen by the endopharyn- geal method by Dr. I. D. Kruskal. A transverse collar incision extend- ing through the skin and platysma myoides was made and the flaps dissected up sufficient to fully expose the seat of operation. These flaps were then protected with towels secured by clamps and by gauze 62 sponges, after which an incision was made in the median line expos- ing the sterna-hyoid muscles which were retracted exposing the cap- sule of the thyroid gland. After two parallel clamps had been placed upon the muscles at right angles to their fibres, at about i inch below the hyoid bone, the muscles were severed between the clamps and re- tracted. The large venous trunks on the surface of the thyroid were carefully doubly ligated and cut between ligatures, and enucleation of the gland was started at the upper pole, the cyst being carefully lifted up as freed, the blood supply being identified and controlled. The recurrent laryngeal nerve was identified. The lower pole extended about one and one-half inches below the upper margin of the clavicle. It was carefully lifted up and rolled out toward the median line, and finally the isthmus was divided. In the course of this procedure the operator remarked that if the surgeon carefully worked outside of the capsule and ligated all blood vessels as they were met with, the lymphatic vessels would also be enucleated and a dry wound would result, and there would be no necessity of painting the raw surfaces with such an antiseptic solu- tion as Harrington's, and drainage would be avoided for the removal of the excess of thyroid juice spilt in the field of operation for future absorption and the production of subsequent post operative hyperthy- roidism. By the method of operating which he followed he left his wound so absolutely dry that he was able to close it and have no trouble thereafter. He was careful to avoid injury to the nerve or to the parathyroid bodies. If he met with any difficulty it was his custom to divide the isthmus first and study the region of the parathy- roids and the blood vessels. At the completion of the neucleation, the trachea exposed at the bottom of the wound was found to be compressed and flattened and displaced to the right of the median line. After final careful hemostasis the muscles that had been divided were resutured. A few interrupted subcuticular catgut sutures co- apted the skin. The skin wound itself was closed by special metal clips which were to be left in place for five days. The use of these clips was resorted to because of the less danger of skin infection that attends such use. No drain was put in place. The operator said that most cases of this kind were allowed to sit up at the end of twenty-four hours. The subsequent history of this case was an un- eventful recovery. ACUTE HEMORRHAGIC PANCREATITIS; EXPLORATORY INCISION; DRAINAGE. Case III. Woman thirty years of age; mother of two children, who gave history that six years ago she first experienced a severe pain over the entire abdomen, which came on suddenly. Was at- tended with repeated vomiting with chills and fever and marked perspiration over the entire body. The attack lasted eight hours, at the end of which time relief was experienced. It occurred during her first pregnancy. One and one-half years later, during a second pregnancy, second month, she then went through with a similar at- tack, almost identical in its features. Eight months later a third attack occurred and for the next five months these attacks occurred every week or two but of less severity than at first. They were re- lieved by enemata. Nine months ago these attacks again began, although not so severe as formerly. They were attended with pain 63 which extended throughout the abdomen and at times radiated to the right shoulder. They were attended with vomiting, chills and fever and her abdomen would become moderately swollen so that it was difficult for her to assume a sitting posture. Four days previous to admission to hospital she was again seized with severe epigastric pain, which radiated to the left lumbar region, attended with vomiting. The attack lasted for twenty-four hours, but the vomiting continued and the abdomen began to swell. She was constipated. No urinary disturbance. In this condition she was admitted to the hospital. Upon admission the abdomen was distended, the abdominal walls were slightly rigid, the epigastric region was doughy to the touch and very tender. The tenderness was present over the entire abdomen ; no abdominal organs could be palpated. Also tender in the left lumbar region, especially at the right costovertebral angle. Right trapezius tenderness also obtained. Blood count: Total 23,500; polymorphonuclears 75; mononu- clears I ; lymphocytes 24. Temperature from loo to 100.4. Pulse 72 to 80. Respiration is normal. Urine negative. Dr. Linder remarked that the previous history of this patient indicated typical attacks of gall stone colic. The last attack started four days ago which differed from her previous attacks for these reasons : The pain was referred to the mid abdomen which radiated to the left of the median line around to the lumbar region. Upon inspection both the abdomen and face showed a slight cyanosis. Pal- pation revealed a distended, soft, doughy abdomen with a sense of fullness in the mid epigastrium and tenderness extending to the left of the median line with special tenderness at the costo-vertebral angle. No special tenderness over the gall bladder and no palpable gall blad- der could be found. The diagnosis of chronic cholelithiasis and acute hemorrhagic pancreatitis was probable, and an exploratory abdominal incision is called for. Ether was then administered by Dr. Kruskal, and the abdomen was opened through a right rectus incision ; coils of distended bluish small intestines appeared in the wound. The gall bladder Avhen ex- posed was found to contain numerous gall stones. It was thin walled and bluish, no obstruction of the cystic duct. Palpation with the finger in the foramen of Winslow showed no stones either in the Ampulla of Vater or in the common duct. Through the gastro- hepatic omentum an opening was bluntly made by the finger to ex- pose and explore the pancreas. Some serosanguinous fluid escaped from the opening. After carefully sponging the cavity exposed, the pancreas was seen to be chocolate colored, containing numerous patches of fat necrosis. The pancreas was punctured in four or five places with a blunt instrument, and a split rubber tube containing gauze was placed down in the retro-peritoneal space. The gall bladder was opened and its contained stones were removed. Dr. Linder remarked that primary hemorrhage into the pan- creas does occur producing the typical lesion of fat necrosis. If this hemorrhage is not too great, these attacks may not be recognized, and the patient may get well from a slight hemorrhage, but such hemor- rhages have a tendency to recur and unless recognized and operated upon usually ultimately terminate fatally. The old conception that diagnosis of acute pancreatitis cannot be made except at an autopsy table, or if made the cases end fatally, does not hold today. In his own service at the Jewish Hospital they have records of at least 64 twenty-four cases of acute hemorrhagic pancreatitis during the past six years and fully 75 per cent had been diagnosed or suspected be- fore operation. It is important that in all operations upon the upper abdomen, where the pathology is not clear, that the pancreas should be exposed and inspected. If this routine was followed a great many more cases would be diagnosed, at least on the operating table. The history of the case just operated upon is typical of acute hemor- rhagic pancreatitis in its early and mild stage. When the pancreas was exposed, however, extensive hemorrhages were found. One of the most frequent conditions that acute hemorrhagic pancreatitis is mistaken for is acute intestinal obstruction. Pain, vomiting, abdominal distention and obstipation occur in both conditions, but the pain in acute hemorrhagic pancreatitis is more severe. It is so great often that a half grain of morphine does not relieve it. In intestinal ob- struction vomiting is more profuse. The differentiating from gastric or duodenal perforation is to be made by the absence of the scaphoid abdomen and the boardlike rigidity and also the absence of any previous history of gastric or duodenal ulcer. The after history of the patient operated upon was an uneventful recovery. 65 VII THE BROOKLYN HOSPITAL. THE ORIGIN AND COURSE OF CHRONIC PERITYPHIL- ITIS John Edward Jennings, M. D. Surgeon Brooklyn Hospital; Surgeon-in-Chief Greenpoint Hospital. THERE is a group of cases in which the symptoms, which had been attributed to the irritation caused by a chronically inflamed ap- pendix, persist, after the removal of that organ to the annoy- ance of the surgeon and patient alike. Forced upon the attention by the fact that the symptoms are unrelieved by operation, it is evident that conditions exist in the right iliac fossa which resemble chronic appendicitis in symptomatology but are due to other causes. The situation is complicated by the fact that almost all removed appendices are declared somewhat abnormal by the sympathetic pathologist and that complete relief of symptoms occasionally follows the excision of organs very slightly changed in gross appearance from the normal. This has led to increased interest in this region with the recognition and study of various pathological conditions associated with pain, constipation and digestive disorders. The French recognized, nearly twenty years ago, a clinical picture which has been described under the term "Typhlo-colite" or "Typh- lite ptosique." Dieulafoy pointed out that there were attacks of pain in the ileo-cecal region which had, he thought, nothing to do with the appendix but which signified the localization of a muco membranous colitis in the cecum. The attack resolves itself into a severe seizure of pain about the cecum which lasts only a few hours and disappears quite suddenly. If the patient is examined during the attack it will be found that tenderness exists on pressure in the illiac fossa but that there is no rigidity. In many cases an elastic body can be felt which may vanish under pressure and appears to be the distended cecum. Vomiting may be present with a slight rise of temperature and a spontaneous diarrhea often ends the attack: more or less tenderness sometimes presists. More recently the same condition has been described in Germany under the name of "Cecum mobile," or "Typhlatonie," etc. In this country, Jackson, Flint and others have described the fine vascularized membranes found upon the ascending colon or cecum. "The membrane," Jackson says, "does not resemble the ordinary conception of an adhesion. It is never adherent to the ab- dominal wall nor to any contiguous portion of the small intestine. Instead it resembles more closely than anything a thin pterygium. In recent cases the membrane is quite free and produces but limited restriction of the underlying colon. In more advanced and character- istic cases it seems to bind the colon close to the posterior abdominal wall and produces such marked angulations and convolutions of the colon as to practically produce a stricture of its lumen." The Theories as to Etiology are three: 69 I — That it is congenital, 2 — That it is mechanical — a physiological response to trac- tion. 3 — That it is inflammatory, either from a spreading peri- tonitis from pomts of original infection without or from infections within the contiguous gut. The studies of Flint and of Eisendrath and Schnoor may be accepted as determining the congenital origin of these structures. "They originate," to quote from Flint, "after the rotation of the gut from the secondary fusions of the peritoneum when the cecum becomes attached to the posterior abdominal wall just over the kid- ney and under the liver. In some instances these attachments, usually confined to the posterior aspect of the cecum and colon, are excessive and extend out over the ventral surface of the first part of the large intestine resulting, with the subsequent descent of the cecum, in their being drawn in the form of a thin veil or mem- brane. In this process the blood vessels take part, a fact which ex- plains the long unbranching course from their origin on the parietal peritoneum downward and forward onto the cecum or colon where they communicate with those of the intestinal wall." Eastman called attention to "the striking similarity of the foetal peritoneal fold described by Jonesco and Juvara and designated by them the parieto-colic fold to the adult peritoneal anomaly described by Jackson as membranous pericolitis and generally known as "Jack- son's veil," and also to the probable casual relationship between the bloodless fold described by Treves and a pocket-like anomalous peri- toneal reflection which is not rare in the adult and which passes from the mural peritoneum upon the right side quite low down, extending upward and inward over the caput coli and vermiform appendix, to be attached to the last two or three inches of the ileum and to the peritoneum of the caput coli. It forms the boundary of a pre-colic fossa in which the cecal head and the appendix may rest, as in a pocket. It is likely that the caput coli with the appendix are not rarely, during operations for appendicitis, shelled out of this peritoneal fold, that is the bloodless fold of Treves, which forms the pocket, being looked upon by the operator as an affair of adhesion forma- tion." He also at the same time called attention to the fact that, "Douglas Reid has described under the name Genito-Mesenteric Fold, a rather common foetal fold of peritoneum which passes from the terminal portions of the ileum into the pelvis" and connected it with the formation of the so-called Lane's kink, and frequent as- sociation of appendicitis and oophoritis. We distinguish the following anatomical forms of these veils or membranes : I — The parieto-colic, in which the veil stretches from the parietal peritoneum at the hepatic flexure over the lateral and ventral surfaces of the ascending colon and cecum. 2 — The parieto-cecal, which extends from the parietal peri- toneum lower down, passes over the head of the ce- cum and may merge with the first type above. 3 — ^The parieto-ileo appendicular, or fold of Treves. 4 — The genito-mesenteric or ileo-pelvic. 5 — The omento-colic, of Flint, which passes over the ven- tral aspect of the colon and is continuous with the omentum. 70 Eisendrath and Schnoor from observations during operations and from examination of ten foetuses, confirmed the position of East- man and drew attention to the similar parieto-colic and genito-mesen- teric folds on the left side. They reported a case which affords proof of the role which the Jackson's veil may play in the produc- tion of acute and chronic obstruction of the ascending colon and cecum. "We are not prepared to state at the present time," they write, "what causes this change in the peri-colic membrane from an innocent persistent foetal structure to the production of a distinct pathological entity." We may then consider the normal anatomy of the peri-colic folds as sufficiently established for us to advance their gross pathology and the nature of the process which brings it about. In a number of cases of acute appendicitis operated on during the attack the condition of the peri-colic membranes, which were present, have been observed. In many of these the veil was found edematous, somewhat thickened, pearly grey in color; and in several, small portions were removed for section and culture. The sections show round cell infiltration; and the cultures, a pure growth of colon bacillus. In all of these cases the peritoneum itself was not in- volved, and the process seemed to be a distinguishing symptom. Localized areas of injection and thickening were made out and from one of these the colon bacillus was isolated. It seems fair to assume that the contraction and band formation, which is found in later cases, are direct sequelae of this infectious process. I have also observed four cases in which the process of veil con- traction on the right side has been recognized at operation and at a later date symptoms have arisen which have been due to a similar process initiated on the left. These cases have also had more or less colitis. I think we may safely say that just as we know how acute infection spreads from the appendix behind the peritoneum, so it may be recognized that a more chronic inflammation in certain cases follows the same paths. This inflammation may be of short duration and followed by resolution, as may be seen if one notes conditions at operation in many catarrhal cases. It may be slowly progressive with remissions and exaccerbations and it may leave in its wake contractures and adhesions. There are cases in which a definitely progressive history is obtainable, beginning as a larvate appendicitis, advancing through the stage of ileocecal disablement to the beginning of a chronic colitis with involvement of the splenic flexure and sigmoid in the peri-colic process. It seems fair, to some authors, to consider these cases examples of a descending colitis, and to charge the peri-colitic bands to infection through the epiploic appendages. The disease may then be defined as follows : Chronic perityphlitis is a process characterized by the presence of areas of subperitoneal congestion, inflammation and cicatrical retraction accompanied by disturbances of ileo-colonic function, by catarrhal and croupous in- flammation of the cecum and ascending colon and sometimes initiat- ing a descending colitis and peri-colitis. The fact that these areas may be seen inflamed during an acute attack of appendicitis, that one or more of them are often seen inflamed, an exacerbation of chronic right iliac pain and that most of them recovered completely after the appendix had been removed render it probable that the infection takes its rise most often in the appendix. The fact that 71 some of them continue to give symptoms after the appendix has been removed calls for explanation. Is the continuation of trouble due to irritation from the scars of contractures unrelieved by opera- tion or is it due to recurrent attacks of inflammation set up by in- fection in the terminal ileum, in the cecum, or in the ileo-colic glands ? I am persuaded that each of these situations may furnish a nidus from which recurrent spreading infections may arise. The terminal ileum is rich in lymphatic tissue, it is the site of ulceration in typhoid, in tuberculosis and perhaps more often than we now admit, of infections not yet recognized as specific. In a recent case a well defined ulcer with edges as indurated as the usual duodenal type, involved two-thirds of the circumference of the ileum from the ileo-cecal valve backward about two inches. It would seem, how- ever, that this type of disease must be rare. The ileo-colic glands are not infrequently found quite distinctly involved in a definite group of cases of appendicitis, most often ob- served in children and adolescents. These cases occur as an immed- iate sequel of a tonsillitis. On the second, third or even the fourth day of throat infection abdominal pains and vomiting begin. The temperature is usually rather high, 103 to 104° F, and as the general abdominal pain and tenderness becomes localized it is often possible to recognize that it is somewhat higher and nearer the navel than the usual site of appendicular distress. Some of these cases go on to suppuration or gangrene, but most of them subside with rest. If such' a case be opened in the catarrhal stage one finds that the glands in the ileocolic angle are much enlarged and that this is much more noticeable than the involvement of the appendix which may even appear nearly normal. There will be found, however, the same retroperitoneal injection and edema that has been mentioned before. The relation of stercoral typhilitis to peri-typhilitis is doubtful It has been noted that the disease has a tendency to progress and to involve the left side and this appears in two different ways : In the first, a catarrhal colitis is followed by the appearance of pain and sensation of gas lodged on the left side. These "gas balloons," as some of the patients call them, are high on the left side — this may be called the diverticular type. In the second, after signs of right ovarian irritation, constipation increases and the sensation of "gas balloons" appears low on the left side. The first variety seems to be due to an extension within the colon and its dissemination in the region in which diverticulae are most often found. The second is due to a spread of the subperitoneal process around the pelvic brim, apparently advancing with the congestion of each menstrual period. These patchy areas of injection and edema may be seen in cases not too far advanced, in which proper search is made. There is a variety of peri-colic's which apparently originates in the gall bladder and descends involving the parieto-colic and omento- colis folds and causing, in its later stages, a rather confused picture of upper and lower disease on the right side. The condition is to be suspected in cases of long standing, inter- mittent right iliac pain and tenderness, in dyspepsia with tenderness in the right iliac fossa, although no complaint of pain is often made. These are typically ileal cases rather than cecal. It should also be suspected in dysmemorrhea of young, unmarried 72 women, especially if right sided ache persists between periods and the digestion is affected. The signs are: tenderness and pain in the same spot or spots at different times, often increased by exercise; delay of bismuth meal ; tenderness and pain on inflation of the colon. These cases should be carefully distinguished from those in which atony and dilatation of the cecum exist without inflammation or ob- structive retraction in the neighborhood. Such cases constitute quite another group, probably to be dealt with in the same chapter with local vagotonia, certainly not here. Treatment: A liberal incision through the middle or around the outer edge of the right rectus should be made so as to reveal the terminal ileum, the cecum and the ascending colon and give access, if necessary, to the right side of the pelvis. The appendix, the cecum and its neighborhood, the situations in which inflamed veils are to be found, are all investigated, as is the gall bladder region. The appendix is removed and if no perityphlitis is found nothing else is done. If there is present also a dilated and prolapsed cecum with evidence of inflamed parieto-colic veils, the veils are severed with a knife, not torn, bleeding points caught and tied, and the dragging cecum suspended in a slit in the parietal peritoneum. If the process involves the pelvis and the terminal ileum, this is taken care of by slitting the ligament, binding down the ileum, and covering the raw area either by folds of the broad ligament or by unrolling the mesen- tery or by rotating the cecum inward as circumstances may suggest. If the ileo-cecal glands are much enlarged they may be removed by careful dissection. If the disease is of long standing and the cecum and ascending colon are bound down by retracted bands, especially if colitis has begun to be evident, it is better and safer to remove the cecum and ascending colon and anastomose the ileum into the beginning of the transverse colon. In the cases of the longest stand- ing in which the muco-membranous colitis has set up toxic symp- toms and in which the patients are much reduced, the surgical treat- ment should be done in several stages. The appendix should be re- moved if this has not already been done, a cecostomy or appendicos- tomy made for irrigation and an ileo-sigmoidostomy performed. At a later date, if necessary, the colon may be removed or as much of it as seems desirable. Such measures will only be necessary in cases in which the colitis has progressed so far as to make simpler measures hopeless. It is desirable that the cases should be recognized early and taken care of at that time. 73 SURGICAL CONSIDERATIONS OF ACUTE DIFFUSE PHLEGMONOUS GASTRITIS. Richard Ward Westbrook, M. D. Surgeon to the Brooklyn Hospital. MONG the less well-known surgical diseases of the stomach is the so-called acute diffuse phlegmonous gastritis. The dis- ease will never attract wide discussion as it is fortunately rare. It is at the same time so fatal that it is unlikely that the most skillful diagnosis and the best surgical treatment will ever save more than an extremely small percentage of cases. It is, however, neces- sary that the unsatisfactory condition of our surgical knowledge of this disease should be cleared up. Suggestions made by certain well-known abdominal surgeons as to treatment are, I am sure, quite inadequate. Some years ago it was my good fortune to ob- serve and operate upon a case of true acute diffuse phlegmon of the stomach which forms the basis of this article. This case, like all the other authentic cases, was fatal in the outcome, but showed clearly the conditions which must be met, if surgery may ultimately be successful in its treatment. Historical. It is stated that the first mention of this rare disease was made by Varandaeus in 1620. In the same century further data were furnished by Borel (1656) and Sand (1695). Occasional ref- erences to the condition are found until 1874 when an important paper by Lowenstein appeared, and another in 1896 by Leith, of Edinburgh. At the present time some 100 cases have been reported. There are two distinctly marked varieties of phlegmon of the stomach: the circumscribed form, or abscess of the stomach wall, of which but few cases are reported; and the diffuse form — with which we have to do chiefly in this paper — known as acute diffuse phlegmon- ous gastritis. A case of the circumscribed variety has been operated upon by Dr. J. Wesley Bovee, of Washington, who recognized an abscess of the stomach wall after abdominal section, opened and drained the same, and was rewarded with a recovery. A second case of this variety was treated by partial gastrectomy, six months after the onset of acute symptoms, by F. Koenig, with recovery. No authentic case of the diffuse form has ever been known to recover, and in only two authentic cases — my own and a later one of J. E. Adams of London — has the diagnosis been made previous to autopsy. Pathology. The diffuse form of phlegmon of the stomach has been likened to a virulent erysipelas. The parallel is striking, the streptococcus being responsible for both conditions, the deeper form of erysipelas spreading in the subcutaneous tissues and often form- ing pus, very much as the phlegmon of the stomach wall extends into the submucous area, also with the formation of pus. The stomach wall is much thickened, sometimes eight or nine times greater than the normal. The thickening is greater in the pyloric portion, where the disease commences and from which it may spread to the whole of the stomach. The thickening lies chiefly in the submucous coat. This is white, or grayish-white, in color, and pus may often be squeezed from small openings in it. Micro- 74 scopically it is seen to be crowded with immense numbers of round cells, in the later recorded cases, the streptococcus has been the organism found most abundantly. The lining mucous coat is usually intact, but in the later stages may be ulcerated through by the underlying suppurative process. The muscular coat is intact at the start, but may also later be destroyed in part, allowing pus to pene- trate it to the peritoneal coat. The peritoneal coat very rarely is per- forated, but usually becomes involved in local peritonitis. The so-caUed circumscribed form of phlegmonous gastritis is due to bacterial invasion of the submucous coat, but of a milder nature. The staphylococcus is probably the infective organism. The mucous and muscular coats are thinned and pushed away from the abscess in the submucous layer. The localized abscess which forms may vary from the size of a bean to three times the size of the closed fist. It may rupture into the lumen of the stomach, or into the per- itoneal cavity. The rest of the stomach may show little or no change. This form has been supposed to go on to spontaneous cure in a num- ber of instances, where pus has been vomited. Vomiting of pus, how- ever, may be secondary to any perigastric abscess wherever arising. Early operation in abscess should be productive of good results. Etiology. The etiology of diffuse phlegmonous gastritis is as yet obscure. It is far more common in men than in women, at least in a proportion of 5 to i. It is chiefly a disease of early adult or middle life. A large proportion of the cases reported have been addicted to alcholic excess. All but a few of the cases are primary or "idiopathic" in their origin, and but a few are secondary to pus-infections elsewhere. A few cases followed operation on the stomach, such as gastroenterostomy, and a few were secondary to the presence of gastric cancer. Gastric ulcer has been antecedent in only a few cases. It is probable that the infectious organisms gain entrance to the stomach wall through the blood current rather than through any abrasion of the mucous lining, as evidence of the latter is rarely found. If the latter were the case, we should expect it to more often accompany gastric ulcer and cancer. Symptomatology. The symptomatology in the early stages of the disease, before the onset of peritonitis, I believe may be considered fairly characteristic, although authorities state that we can hardly do more than guess at the diagnosis. I am strongly of the opinion that I should be able to make the diagnosis in a second case so characteristic as my own. It is a violent disease from the start, and its abrupt onset may suggest corrosive poisoning. The earliest and perhaps most per- sistent symptom is vomiting. This is repeated at short intervals and is so continuous as to be a very distressing feature. It is said to cease in some cases a day or two after the onset, and later to recur as peritonitis advances. The vomited material is watery, becoming bile-stained, and later darkish as it contains more material from the upper bowel. Pain soon follows the sudden onset of the vomiting, and becomes the most prominent symptom. It is localized in the epigastrium, and is severe and continuous. In some cases it is said to be delayed, or absent. Pressure over the epigastrium elicits marked tenderness. Rigid- ity is not of high degree before peritonitis has advanced, but there 75 is present a very distinct sense of increased resistance in the epi- gastrium, over an area which the hand may cover. The pulse at first is full, but acquires fairly early a weak and rapid character. The temperature may range from ioo° to 105°. Chills often occur. Constipation, or constipation preceded by diar- rhoea, is apt to be the rule. Diarrhoea sometimes exists. The thirst is extreme as a result of the inflammation and the constant vomiting. Hiccough is commonly present. The patient's mental anxiety and restlessness are very pronounced, and he has the appearance of being very gravely ill. Leith states that the average duration of the cases analyzed by him was six and a half days before death occurred. It may occur much earlier. Death is produced by septicemia with general peri- tonitis. Acute Pancreatitis. Perforated Gastric or Duodenal Ulcer. PhlegmonouB Gastritis. Previous history Healthy, or occas- ional attacks of indi- gestion. May have had gall-stone history. Periodic or persist- ent indigestion. Healthy ; alcoholism, with or without gastri- ns. Gall-stone historr negative. ^e Chiefly middle age. Early adult and middle age. Chiefly middle age, but may occur from 11 to 76. Bex Male, in large pro- portion. Male, chiefly. Male, In large pro- portion. Chill at onset Usually lacking. Usually lacking. Frequently present. Vomiting Follows the pain. Becomes bile-stained, later black from al- tered blood. Follows the onset of pain. Blood may be vomited. Commences at once and is usually con- stant. Becomes bile- stained and dark. No blood present. No pus in early stages. Thirst Usually extreme. Less marked. Very marked and often intolerable. Pain Is the first symp- tom, accompanied with falntness or collapse. Is the first symptom, accompanied with falnt- ness or collapse. Appears after the vomiting, and often after a chill. Temperature Irregular, usually low, but may be high. May be subnormal early. Later high. Likely to be high 102° to 105°. Pulse Rapid and small. Rapid and small at the onset. From 100 to 110 early ; later very rapid and thready. Hiccough May be present. Not prominent. Frequently present. Bowels Constipation, usu- ally extreme. Usually constipation. Either constipation or diarrhoea. Tenderness Extreme in epigas- trium. Extreme in epigas- trium. Very marked, but not extreme. Tumor Rarely palpable tu- mor. Increased sense of resistance with dis- tention. None. None. But Increas- ed sense of tissue re- sistance. Rigidity in up- per abdomen Apt to be extreme. Extreme. Not extreme, but well marked. Leucocytosis 8000 to 39000. Averaging 20,000 to 30,000. 30,000 to 40,000 In cases observed. Urine Sugar may be pres- ent. Negative. Negative. Jaundice Slight jaundice usu- ally present. Usually absent. Slight, In 16% of cases. 76 Differential Diagnosis. The diagnosis must be made chiefly with regard to differentiation from acute pancreatitis and perforated gas- tric ulcer. At the very onset it may simulate acute ptomain or other poisoning, but on the second day it would require differentiation from the conditions mentioned. The accompanying parallel col- umns will show the distinguishing symptoms most readily. It will be seen that it is possible to make the diagnosis in the earlier stages of the disease, although it is but a narrow shading off from the picture of acute pancreatitis. An accurate history of the onset, combined with a careful observation of the several points of variation will throw the weight of evidence towards the correct diagnosis. At any rate, the diagnosis of an intra-abdominal surgical calamity requiring laparotomy should ordinarily be possible within some hours after the onset of the disease. Report of Writer's Case. My own case was that of H. A., age 51, captain of harbor Hghter, married. Previous history negative. Denies syphilis. No history of gall-stones. Has had no pus infec- tion of any kind for months past. Has bad teeth, but there is no trace of pyorrhoea alveolaris. Is an habitual drinker, chiefly whiskey and beer, but is rarely intoxicated. Has always had a good stomach up to six months ago, since when he has been inclined to vomit his breakfast. Present History. Was well on Sunday, Jan. 27, 1908, eating as usual, and having cod-fish for supper. Went to work on Monday, and felt well until the afternoon, about 3 o'clock. Was then seized with chilly sensations. Went to bed on board his boat, was given hot coffee and whiskey and became warm. At 5 o'clock began to vomit greenish material. At 6 o'clock reached home by means of the street cars, without assistance, and at this time pain commenced in the epigastrium, and continued steady and severe. The pain was not relieved by pressure, but he received some relief by steadying the epigastrium with his hand. Vomited continuously all that (Monday) night, and on Tuesday, also hiccoughed steadily. Thirst was extreme ; he had no sleep at all and chills returned. At noon was seen by his family physician. Dr. W. G. Hirseman, who found him with thighs flexed upon abdomen, with anxious countenance, heavily coated tongue, temperature 1005^°, respiration 35, pulse 85, good quality. The abdomen was not distended, but palpation revealed marked ten- derness of the epigastrium most intense to the right of the middle line. Below the umbilicus deep pressure did not elicit tenderness. There was no icterus. The patient was given one-fourth grain of morphine by hypodermic injection, and a powder for the vomiting. On the return of the physician at 8 p. m. the patient's symptoms were increasing, the abdomen showed slight distention below the umbilicus, and marked distention in the epigastrium. The temperature was ioi^°, respiration shallow, and pulse 100, small, and intermittent. On consultation with Dr. L. W. Pearson, the patient was sent to the Brooklyn Hospital, as probably requiring surgical treatment. I examined the patient at 1 130 a. m., Wednesday, less than thirty- six hours from the time of onset of the illness. The patient was seen to be a man of large frame, with every indication of severe suffering, complaining of constant epigastric pain, worse in paroxysms, vomit- ing slightly every minute or two, and hiccoughing. Pulse averaged a little over 100 and was regular. Examination showed a moderately distended abdomen, soft, and not tender below the umbilicus, but 77 very tender above. The whole epigastrium was tender, but the greatest tenderness was to the right of the middle line, at the point over the head of the pancreas where greatest tenderness is also shown in acute pancreatitis. The flat hand laid upon the epigastric area received a sensation of resistance or tumor, nearly the size of the palm, but not of a high degree of rigidity. Percussion gave a tympanic note, extending well up into the left hypochondrium. The combined findings suggested to my mind a distended stomach over- lying a pancreatic tumefaction, or of tumefaction or pus collection in the lesser omental cavity. A few rales were heard at the base of the left chest. The blood test showed a leucocytosis of 40,000. A diagnosis of an intra-abdominal calamity was made, strongly suggesting acute pancreatitis or a perforation of the pos- terior stomach wall, and operation advised. Examination under ether gave the same impression to the hand. Operation. Vertical incision through rectus muscle, four inches long, one-half inch to right of middle line. Preperitoneal fat and peritoneum seen to be slightly edematous. Sero-pus escaped on incising peritoneum. Immediately, the stomach wall presented it- self in the wound, thickened and boggy, with highly reddened but smooth peritoneal coat, showing no evidence of ulcer or perfora- tion. Further examination showed a segment of the stomach wall about 3>4 inches in breadth to be involved, the thickening apparently extending around the circumference of the stomach, although the thickest part lay in the anterior wall. This thickened segment com- menced with a well-defined border about i^ inches from the pylorus, and the normal wall of the pyloric area could be invaginated with the finger into the thickened segment, and the thickened wall palpated in that manner. The border of the thickened segment extending to- ward the cardia of the stomach was less well defined, and there was some thickening shading off towards the cardia. The abdominal incision was increased to 53^ inches, and an exploration was made through the meso-colon into the lesser sac, but revealed only a smooth, thickened posterior stomach wall, gently adherent. The meso-colon and lesser omentum were both very edematous and thickened, and a few enlarged lymphatic glands could be felt along the greater curvature of the stomach. Pancreas and gall-bladder were both found to be normal. It was decided to incise the stomach wall in the thickened area and a longitudinal incision, three inches in length, was gradually made down through the thick- ened coats. When the submucous layer was reached, drops of pus oozed freely out of small openings the size of a canary seed. Similar small cavities, near the pyloric margin of the thickened area were seen to be filled with opaque coagulum, not yet broken down into pus. The stomach wall was over half an inch in total thickness at this point. As far as the interior of the stomach could be seen and felt with the finger through the opening, the mucous lining was deeply congested and smooth, no evidence of erosion or ulcer being found. The condition was then recognized as a diffuse phlegmon of the stomach wall, and the question of drainage became the important one. The transverse colon was completely collapsed, but the jejunum was moderately distended, and dark bile-stained fluid welled freely up into the stomach from the duodenum. It was decided to trust to a gastrostomy for drainage, leaving the incisions in the stomach and abdominal wall as freely open as possible. The drainage tube was a 78 large sized stomach tube and was passed through the pylorus six inches into the duodenum. The incision in the stomach wall was loosely sutured with a catgut guy-rope suture at each end pene- trating only to the submucous layer and left long and the stomach lifted up into the abdominal incision and held there by tacking the catgut guy-rope to the abdominal wall on each side of the incision. Two wicking drains were passed into the lesser peritoneal sac, and three large gauze tampons were packed freely about the involved area of the stomach to isolate it in some measure, and to drain the peri- toneal cavity. The abdominal incision was closed to two-thirds its extent with through and through silk-worm gut sutures. The drain- age tube was sutured to the skin incision. Drainage made its way up freely through the tube from the duodenum, and the patient was taken back to his bed in fairly good condition. All vomiting ceased at once and the bile-stained fluid which passed from the duodenum by siphonage into the bottle attached, amounted to many ounces in the next twenty-four hours. The patient was allowed to suck ice wrapped in gauze to relieve his ex- treme thirst. He retained large quantities of saline infusion by slow absorption from the rectum after the method of Murphy. The gauze tampons in the abdominal incision drained very freely. There was no leakage from the stomach about the tube. The stomach area was no longer tympanic to percussion. The patient passed good amounts of urine, and seemed generally improved, talking freely. He still complained of the epigastric pain, however, which was but partially relieved by the operation. The pain came in marked paroxysms, emanating from the stomach area, and not due to general periton- itis. Thirty-six hours after operation, the upper abdomen was very sensitive, and the skin hyperesthetic. Abdomen was still but moder- ately distended, and but moderately tender below the umbilicus. Much drainage persisted from the wound. Several stitches were removed, and the stomach inspected as far as possible, and could be seen to be purplish in color along the greater curvature. Pulse 120. Patient not so clear headed, but he asked if condition was serious. On the third day after operation, patient was still suffering the paroxysmal pain; conscious, but unable to speak connectedly. Kidneys had ceased to secrete. Death ensued 3^ days after operation and 5 days after onset of attack. Report of Autopsy. Body well nourished. The peritoneum is everywhere somewhat injected and bathed with sero-pus, covered in spots with fresh lymph. The intestines are slightly adherent with lymph. The appendix is normal. The mesentery is very friable. The meso-colon is inflamed, thickened and covered with lymph. The gastric-colic omentum, more particularly at lower curve of stomach, is inflamed and edematous. The pancreas is normally located and apparently normal in size and consistency. Anterior aspect of the stomach is intensely hyperemic, studded everywhere with petechiae, covered with fresh lymph over the anterior duodenal half. The mesentery contains a great deal of fat and is somewhat edema- tous. The mucous membrane of the small intestine is everywhere cyanosed, somewhat edematous, excepting in the upper part of the jejunum which is pale and edematous. It is intact. The caput coli is normal. The mucous membrane of the larger gut is moderately congested and edematous. 79 The anterior mediastinum is normal. The superficial area of cardiac dullness is considerably increased. There is a total synechia of the left pleural cavity. Also a total synechia of the right pleural cavity, the adhesions being very ancient and firm. The heart is much enlarged; the epicardium thickened and opaque and studded with petechiae at the base. The left auricle is somewhat dilated and hypertrophied. The auriculo-ventricular orifice is large. The valve shows a moderate amount of atheroma anteriorly, in an early stage apparently; otherwise normal. The tricuspid orifice is very large; admits of four fingers separated. The valve seems to be normal. The myocardium is considerably thickened in both ventricles, firm in consistency, a trifle brownish on section. All of the cavities of the heart are markedly enlarged: eccentric hypertrophy and dilatation. Lungs. — The left lung is about normal in size ; somewhat heavy, crepitates feebly on pressure. On cross-section the cut surface is very dark and moist. The entire organ is intensely congested and edematous. The right lung is somewhat enlarged, heavy, crepi- tates feebly on pressure. On cross-section the cut surface is very dark and moist. The organ is intensely congested and edematous. The liver and the diaphragm on its under surface are united by old firm connective tissue. The sub-diaphragmatic lymph nodes are glued together. Diaphragm contains a large calcareous mass. Spl,EEn. — The spleen is large. The capsule is thick. On cross- section the surface is dark mahogany, moist; the pulp easily scrapes away; the trabeculae are somewhat hyperplastic. Pancrkas. — No edema or pus in pancreas. The lower surface of the gall-bladder is covered with plastic lymph. Organ is intact. No calculi. Liver. — The liver is large, somewhat firm in consistency, surface is smooth below and covered with old inflammatory tissue above. On cross-section the cut surface is smooth and presents no further distinguishing features. Kidneys : — The left kidney is very large ; the capsule is adherent in spots. Areas of depression on the surface of the organ, which is otherwise finely granular. On cross-section the cut surface is dark and cyanosed; cortex everywhere swollen; markings distinct. The right kidney is small. The capsule is everywhere adherent. It con- tains three cystic cavities filled with serum and fibrim. What remains of the cortex is moderately swollen. The markings are somewhat indistinct. Stomach. — The stomach is greatly enlarged, the mucous mem- brane is everywhere thickened, congested in spots, showing many petechial hemorrhages. The pylorus is normal as far as the mucous membrane is concerned. The submucosa and muscularis of the stomach are phlegmonous. The whole stomach wall in the pyloric region is very thick, perhaps more than half an inch. This condition involves all of the lower aspect of the stomach, only a small area at the cardiac end being free. No evidence whatever of ulceration. The duodenum is moderately congested, edematous; otherwise free from change. The stomach is free from pus. Microscopic and bacteriological examinations showed the pres- ence of the streptococcus. The streptococcus was also obtained from one of the kidney cysts. For the report of the autopsy, I am indebted to Dr. J. M. Van Cott. 80 Analysis of Operative Cases Reported. There are but five -authentic reported cases, in addition to my own, where surgery has been employed in acute phlegmonous gas- tritis. Of these, two have already been referred to as being of the circumscribed variety. Of the acute diffuse variety, but three authentic cases have been reported as having been operated upon, and in two of these the true condition was not recognized until the autopsy. The first case was of Leith, of Edinburgh, who in 1895, operated several days after the onset under the diagnosis of general peritonitis, supposed to be secondary to typhlitis, making an incision below the umbilicus and washing out and draining the abdomen. The patient died in collapse several hours after operation. Autopsy showed a typical acute phlegmon of the stomach. The second case reported was that of lycnnander, who, in 1898, operated on a woman of 29, with a history of gastric symptoms dating back two or three years, who gave evi- dence of a beginning general peritonitis following a supposed per- foration of the stomach or duodenum. No perforation was dis- covered, the abdomen was merely drained, and the patient died sixty hours after operation. Autopsy disclosed a diffuse phlegmonous gas- tritis involving the entire organ, the portal of infection probably hav- ing been through two non-perforating ulcers of the lesser curvature. The third case was a girl, aged 13 years, operated on by J. E. Adams, St. Thomas's Hospital, London, under the diagnosis of per- forative peritonitis with general peritonitis, four days after the on- set. No lesion being found at the appendix, exploration of the stomach showed no adhesions or perforation, but stomach walls an inch in thickness when held between the fingers. The condition was present throughout the stomach, but more noticeable in the pyloric half. By exclusion, the diagnosis of acute primary phlegmonous gastritis was made. Beyond drainage of the peritoneum, no further operative attempt was made. The child lived four days after the operation. Peritoneal fluid removed at operation gave pure cultures of the pneumococcus, and cultures made at autopsy gave the pneu- mococcus from the submucous and serous coats of the stomach. Included in the list of reported cases of phlegmonous gastritis in Robson and Moynihan's "Surgical Diseases of the Stomach" are three cases which should have no place under that heading. One of these (Case 84) is an instance of perigastric abscess following an eroding gastric ulcer of the posterior wall, where posterior gastro- enterostomy was done by Robson and recovery ensured. In another chapter, this case is not claimed as one of phlegmonous gastritis, but its incorporation with the list of cases has caused misleading quota- tions of the case as a cure of phlegmonous gastritis by gastro-en- terostomy. Another case (No. 85) was an instance of prolonged gastritis, the mucous lining only being involved, the patient dying after gastro-enterostomy, by the same operator. A case which has been much quoted as a recovery from acute phlegmonous gastritis by mere abdominal drainage was that oper- ated upon by Mickulicz, and reported (1902) by Lengemann. The patient was a young woman of 18, with prolonged history of anemia and gastric ulcer. Operation was done with expectation of finding a perforation. Bloody serum and gas-bubbles were present in the abdominal cavity, but no perforation was located. The stomach was thickened on its anterior wall, and two yellowish-gray maculae 81 presented there, each about the size of a silver quarter. No incision was made into the stomach wall, and the operator is said to have made his diagnosis on the symptom-complex. Gauze drainage of the abdominal cavity and over the inflamed area of the stomach brought about a prompt recovery. From my own experience with an un- doubted case of diffuse phlegmonous gastritis, I cannot believe that this case was correctly diagnosed. I cannot find, therefore, that there is any reliable proof of the cure of diffuse phlegmonous gastritis by medical or surgical means to the present date. Possibilities of Surgical Cure. One must admit that the chance of a surgical cure is extremely small. The object of this paper is to establish the lines along which surgery must proceed if there is to be any hope of cure. Robson and Moynihan suggest that benefit may accrue from drainage and rest of the stomach by gastro-enterostomy or gastrostomy. Gastro-en- terostomy, I am sure, would be an entirely unfit procedure, and would only defeat the end sought by adding additional traumatism to the stomach wall and further the spread of the infection. Gastrostomy would be also inadequate as shown by my own case, where a free incision into the heart of the phlegmonous area, and rest to the stomach, had no noticeable effect in staying the spread of the in- flammation. The claim made by Lengemann, who reported the case of supposed cure by Mickulicz, is altogether without appeal to surgical judgment. He states that the free drainage of the peritoneal cavity by gauze tamponade must have been sufficient in that case to limit peritonitis and at the same time to bring about a cure of the early require either the most complete drainage of the tissues involved, by multiple incisions, or wide excision of the same. In my own case, case can surgery hope to cure. Such treatment would seem to drainage. This might be accomplished by whipping over the cut phlegmon of the stomach wall. There is no reason whatever why a phlegmon confined within the walls of any abdominal viscus should be cured by simple drainage of the peritoneal cavity. Mickulicz's case, in the light of my own case, strongly suggests an induration of the stomach wall secondary to ulcer. My belief is that only in the most radical treatment of an early the thickened area, though not broad, extended from the anterior wall through both greater and lesser curvatures, around nearly a complete segment of the stomach, the posterior wall immediately behind be- ing also thickened. Multiple incisions down to the mucosa would manifestly have been very difficult in adequate degree in my case. It is possible that a still earlier or more limited case than mine might be adequately treated by free multiple incisions combined with gas- trostomy. The possibility of having present a developing circum- scribed abscess should be kept in mind in deciding the treatment, as incision should there suffice. My own case showed plainly in the submucous tissues the spreading gray lines of a streptococcus infection with little ous. I believe that nothing short of a partial gastrectomy was indi- cated in my case. The risks of such a step would have been ex- treme, but not entirely beyond hope. The condition being absolutely hopeless otherwise, one would be justified in taking extreme opera- 82 tive risk. In a similar case, I would do partial gastrectomy, adopt- ing at the start the usual technique. At the cardiac end, the clamps should be applied two or three inches beyond the marked thickening if possible. At the duodenal end, less distance beyond the involved area will suffice, as the inflammation does not tend to attack the duodenum. After cutting away the stomach with knife or scissors, a large-sized, moderately stiff drainage tube or catheter should be passed several inches into the open end of the duodenum, and the latter closed about it with purse-string suture. This tube will an- swer the double purpose of drainage of the duodenum, from which, in my case, a large quantity of dark fluid constantly welled up, and also for feeding later on, as in ordinary duodenostomy or jejunostomy. The treatment of the stump of the stomach remaining would be simply that of staying of hemorrhage from the cut surface, and drainage. These might be accomplished by whipping over the cut edges with catgut, and leaving the cavity unclosed, to be surrounded with a gauze pack; or the walls might be quickly sutured together with catgut for the most part of the opening, and a large soft rubber drainage tube left in the cardia. A large, free pack of simple gauze left in the stomach area might provide sufficient drain- age of that space and the peritoneal cavity. If the patient recovered, and were in fit condition, an anastomosis of the jejunum with the retracted cardiac end of the stomach, through a left rectus incision, might be done some weeks later. If this were not feasible, life might be prolonged by the duodenostomy. Conclusions. 1. Acute diffuse phlegmonous gastritis is a rare form of inflam- mation of the wall of the stomach, involving chiefly the submucous layer, and produced usually by streptococcus invasion, locally, or through the blood current. It is to be distinguished from local abscess of the stomach wall, which is still more rare. 2. It occurs chiefly in middle and late-middle life, but may occur at any period. 3. It is to be distinguished principally from acute pancreatitis and perforated gastric ulcer, an important difference being the on- set of vomiting before pain. 4. 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Eandbuch der allgemeinen Therapie. 86 RHINOPHYMA Walter A. Sherwood, M.D., F.A.C.S., Surgeon to the Brooklyn Hospital. When acne rasacea becomes exaggerated to what may be called its third or extreme stage, an increase in connective tissue takes place, the tip and sides of the nose become converted into a lobulated mass, so great as to form one or more pendulous tumors which overhang the lip. The condition is known as Rhinophyma. Digestive disturbance from whatever cause, producing reflex dilatation of the nasal blood vessels and capillaries, is the basic etiolog- ical factor. Rhinophyma occurs after middle life, most often in males and usually in subjects who are accustomed to rich food and a free in- dulgence in alcoholic stimulants. The extreme cases which require surgical measures for their relief are comparatively rare. The following pathological note has been kindly supplied by Dr. Nathan T. Beers : "As the result of hypemutrition and chronic hyperemia of the skin of the affected parts, the blood vessels and capillaries become permanently enlarged. The sebaceous glands are involved and enorm- ously distended. There is pronounced hyperplasia of the dermic connective tissue elements. Nodules, at first gelatinous and later fibrous in character, gradually develop. The increased vascular dilatation is due not only to arterial engorgement but also to a blocking off of the venous return as the result of follicular suppura- tion and consequent formation of cicatrices." The cartilage in some cases becomes hypertrophied. In a few of the cases reported the growth of the tumor-like formations has been rapid. Most of them, however, are of slow growth usually covering a long period of years. The condition must not be confused with Rhinoscleroma, a chronic granulomatous process affecting the lip, nares and adjacent structures and resulting in sclerosis and nasal deformity. This disease was first described by Hebra. It exists in the south-eastern countries of Europe and is exceedingly rare in the United States. The treatment of Rhinophyma is surgical and the operative method employed will depend on the characteristics of the individual case. Report of Cass W. L., aged 63, was recently referred to the writer by Drs. N. T. Beers and Raymond Clark, under whose care he had been for the correction of other conditions and for the purpose of attaining a proper degree of physical fitness in order that he might submit himself to the risk of a general anesthetic and operation. He had been the subject of an increasing nasal deformity which had started as an acne rasacea about twenty-five years ago. During the last year the size and unsightliness of the condition had increased 87 so rapidly as to be a matter of extreme embarrassment to himself, his family and his friends. The appearance of the man when he pre- sented himslf is well shown in the accompanying photographs (Figs. 1, 2 and 3). The enormous enlargement, the overhanging lobulated masses and the wide-open crypts of the sebaceous glands are well illustrated. The entire organ presented a deep, purplish red appearance with enormously engorged blood vessels. After careful consideration of the several methods of attacking such a condition it was decided to remove completely the diseased tissues and cover in the resulting raw surface with suitable skin grafts at one sitting. The method employed was practically the same as that described by Binnie in his work on operative surgery. The patient was referred to the service of the writer at the Brooklyn Hospital where the following procedure was carried out : Warmed ether vapor by Dr. Gwathmey administered through a mouth canula under pressure of a motor-driven pump. Step 1. — Gauze tampons introduced through nares to prevent inflow of blood into the naso-pharynx. Step 2. — With the forefinger of the left hand in the nostril as a guide, an incision was made all around the growth from the middle line outward. A straight incision was then made through the mid- line from above downward. These were carried down to but not into the cartiliage (Fig. 4). Step 3. — The edge of the tumor mass was grasped with forceps and all the diseased tissues within the line of incision were cut away first on one side and then on the other (Fig. 5). Care was taken to preserve the normal outline of the nostril and to prevent the knife from entering the cavity of the nares. The hypertrophied cartilage was shaved off with a knife until it assumed normal proportions. Step 4. — Hemorrhage, which of course was very profuse and continuous, was controlled by pressure, hot pads and the ligation of the larger vessels. Step 5. — The raw surface was then covered with good-sized Thiersch grafts (Fig. 6) taken from the outer side of the patient's arm. The principal steps of the operation will be readily understood from the accompanying drawings. The grafts were covered with silver foil, a dry gauze com- press applied and the parts protected from injury by the application of a rubber nose guard such as is used by football players. All dressings were removed on the fifth day, the grafted area was dusted with aristol and left exposed to the air and sunlight. Serous exudate was considerable and as the result of it a hard dry crust formed and covered the entire nose. This was in no way disturbed until two weeks had elapsed when it was softened with cold cream and gradually and carefully peeled off with forceps. It was found that all grafts had retained their vitality. The process of epithelial repair was very rapid, and at the end of three weeks the entire nose was com- pletely covered with a new healthy skin of a color corresponding to the rest of the face. The parts were smooth, the contour of the nose was normal, and there was very little scar formation (Fig. 7). The appearance of the nose has steadily improved and now ap- pears as in Fig. 8. The chief difficulties of such an operation are as follows: 1. The proper choice of an anesthetic and method of administer- 88 Fig. 1. — Rhinophyma. Condition before operation. Front view. Fig. 2. — Rhinophma. Condition before operation. Side view. Fig. 3. — Rhinophyma. Condition before operation. Anterolateral view. Fig. 4. — Rhinophyma. Incisions of operation. Fig. S. — Rhinophyma. Method of removing tissue. Fig. 6. — Rhinophyma. Wound covered with skin — grafts after removed of diseased tissue. Fig. 7. — Result after operat.ion for rhinophyma. Fig. 8. — Result after operation for rhinophyma. ing it. Rectal anesthesia is ideal for such operations but was not deemed advisable in this case. 2. The danger of hemorrhage and difficulty of controlling it dur- ing the dissection of the tissues. 3. The density of the tissues and absence of any line of cleavage makes dissection tedious and favors wounding the cavity of the nares. 4. The uncertainty of the healing process. The result obtained was so satisfactory and gratifying to all concerned, that it would seem to warrant the brief report herewith presented. The photographs are published by permission. 89 VIII THE NORV^EGIAN HOSPITAL. CANCER OF THE RECTUM. H. Beeckman Delatour, M.D., F.A.C.S., Surgeon-in-Chief to the Norwegian Hospital. URGERY of the abdominal viscera through improvements of technique and added experience of operators has been deprived of many of its former complications and is attended by a con- stantly diminishing mortality. Operations on the pelvic organs and the appendix have long since become commonplace. Within the past few years surgery of the upper abdomen, the stomach, liver, and gall bladder has been extended and perfected, and today is approached with much more confidence than formerly. Malignant disease of the intestine, however, has been much neg- lected and operations have been postponed until acute symptoms, such as obstruction, have developed and forced interference. During the past three or four years these Cctses have been diagnosed in the earlier stages and more radical operations are being undertaken with a marked reduction of operative mortality and a very decided gain in permanent cures. Cancer of the rectum has been the subject of operative attack for many years, but the methods employed were such that many cases were passed over as inoperable or were so operated that not suffi- cient bowel was removed to insure a permanent result. The hesitancy of the surgeon to produce an artificial anus has passed many a case on to a period of prolonged suffering and ultimate death. "I would rather die than have an artificial anus," is a statement we have fre- quently heard and given expression to ourselves. The very idea of it is repugnant. This feeling has delayed our progress in the treat- ment of malignant disease of the sigmoid and rectum and been re- sponsible for the infliction of prolonged suffering on many. Inexperience, tending to high operative mortality, has also been a factor in leading one to pass upon a given case as inoperable. Very interesting in this connection is the paper of Mayo in which he com- pares the percentage of operable cases at their clinic at different periods and also the operative mortality of the same. During the period from 1893 to 1910, there was an operative mor- tality of 17.8 per cent.; from 1910 to 1913, it was 17.17 per cent, with an operability of 51 per cent. During this period only about one-half the cases examined were considered subjects for a radical operation. For the years 1913, 1914 and 1915, the mortality averaged 12.5 per cent, and the operability 71.8 per cent., while the operations were made more radical. During this period nearly three-quarters of the cases examined were operated, upon. With further experience and due care in selecting cases the mortality will be lowered and the per- centage of cures increased. Early diagnosis is the keynote of success, but we must con- stantly bear in mind that cancer of the bowel is slower of metastasis 93 than cancer in other portions of the body, and that many apparently advanced growths can be successfully removed with a long period of immunity from recurrence and possibility of permanent cure. In doubtful cases exploratory operation is certamly justifiable, and should be performed in cases of persistent intestinal conditions m patients beyond thirty-five years of age, when other means have failed to reveal the cause of the symptoms. We must not wait for emaciation and cachexia to develop, for in these cases they appear late and the patient is then quite likely in the inoperable stage. Having made the diagnosis of cancer of the lower bowel, what shall be our method of attack? Shall it be from the perineum, through sacral section, by the abdominal route or by a combination of these? This must depend somewhat on the individual case, but no operation should be undertaken unless it is sufficiently radical to elimin- ate the disease. The frequency of recurrence in the past has been due to a too great desire to retain the anus in its normal position, and the sooner the surgeon can realize that this should be the last consideration the quicker shall we see an increased percentage of last- ing cures. It is our belief that very few cases can be satisfactorily operated by either the perineal or sacral routes alone ; and, further, the ab- dominal part of the operation is of immense importance in permitting a thorough exploration of lymph glands and liver to determine the amount of extension of the disease. If there is positive evidence of involvement of the liver, no radical excision should be undertaken. Enlargement of the lymph glands does not contraindicate operation, for in many cases these glands are found to be the seat of a simple inflammatory process and not due to extension of the growth. If an artifical anus has to be produced, should we endeavor to place this in the perineum or on the abdomen? Careful watching of several cases has convinced us that the abdominal anus is the more easily cared for by the patient. The perfection of the technique of producing the abdominal anus, and teaching the patient its proper care together with the application of a correctly fitted apparatus have so reduced the disagreeable features of this condition that we no longer hesitate to advise our patients to accept the operation. The abdominal-perineal operation in either one or two stages is our preference, and of late we have been better satisfied with the one stage operation in those patients in whom a sufiicient time could be given to preliminary preparation. In cases of obstruction, either complete or nearly so, a preliminary colostomy should be done in order that the bowel may be properly emptied and cleansed, for the mortahty is largely due to sepsis from escape of feces during opera- tion. The method of procedure varies with different operators, but a careful study fails to reveal any very radical differences. The most recent descriptions are those of Jones of Boston, and Cofifey of Port- land. The method of Coffey we have never attempted as it does not seem practicable. The operation which we have followed during the past four years in eight cases without any operative mortality and so far no recurrence, is similar to that described in the text books. Operation: With the patient well elevated in the Trendelenburg position, the abdomen is opened in the median line and an exam- 94 ination of the extent and location of the growth is made ; the liver is also examined for evidences of involvement. The intestines, ex- cept the sigmoid, are then carefully placed in the upper abdomen and protected by a large gauze pad, thus leaving the pelvis clear for our manipulations. The sigmoid is now lifted out and its mesentery traced to the promontory of the sacrum where the inferior mesenteric artery can be felt. The peritoneum is then incised and the vessel ligated in two places, between the upper and middle sigmoid branches, and the artery divided. This insures proper blood supply to the proximal sigmoid which is to be used for the colostomy. By further separation of the peritoneum to the left, the left ureter is exposed. The mesen- tery is then divided from behind forward up to the edge of the bowel. The incision through the peritoneum is now carried down- ward parallel to the bowel and about one inch from it to the bottom of the pelvic pouch and then these incisions are joined across the front of the bowel. By blunt dissection with the fingers the rectum, to- gether with the mass of fat, is separated from the hollow of the sac- rum, down to and, if possible, beyond the coccyx. If the vessels have been ligated above, this is accompanied by very little bleeding. The next step is to free the bowel from the bladder and prostate, and in doing this great care has to be exercised not to injure the ureters. The dissection from above is carried down as far as possible for this simplifies greatly the second stage of the operation. The division of the bowel is not made until all dissection has been completed. A large gauze sponge is now packed in the pelvis and soon stops any oozing that may be taking place. Two clamps are now placed on the bowel at the point selected for division, the bowel is severed by the actual cautery and both ends inverted and closed by silk suture. The gauze pack is next removed from the pelvis, and the distal portion of the sigmoid and rectum placed in the pelvis and covered with a small gauze pad. The edges of the divided peritoneum are next sutured by continuous chromic suture over the pelvis, thus excluding it from the general peritoneal cavity. Where the amount of bowel to be removed was too large to pack into the pelvis and permit suture of the peritoneum over it, we have removed a large segment of the freed portion, after properly closing the lumen by heavy silk ligature and then dividing with the cautery. We next proceed to the production of the colostomy as follows: A sufficient amount of bowel is brought forward so that about two inches will project beyond the skin, the bowel is then sutured to the peritoneum in the upper portion of the wound, the fibres of the rectus muscle are separated and the anterior sheath divided and through this the end of the intestine is passed and brought out beyond the skin where it is fastened by several silk sutures. After final cleansing of the abdominal cavity the wound is closed in layers and a gauze dressing applied. The sutures closing the lumen of the bowel are left in place and the bowel is not opened until from the third to the fifth day. The method of producing a colostomy described by Brinsmade has given very satisfactory results; as yet we have not used it. The further steps of the operation may now be carried out if the patient's condition will permit, or may be delayed for several days. As this procedure rarely takes more than eight to ten minutes it can usually be carried out at once. The patient is put in the lithotomy posi- tion with the pelvis well elevated, the anus is surrounded by an incision 95 through the skin and then closed by a strong silk suture. The levator ani is next divided and the rectum separated from the prostate or uterus in front and the remaining tissues attaching it to the COCC30C divided. The free end of the sigmoid can now usually be seized and brought through the wound and the remainder of the section be done from above downward. There is usually very little hemorrhage, the only vessels of importance being those near the skin and easily reached. In this way from fifteen to twenty inches of the bowel are removed. The gauze pack is now removed, the wound dried out and the large cavity remaining is lightly packed with zinc oxide gauze and the anterior portion of the perineal wound closed by interrupted silk sutures. If thought best the uterus and adnexa, or portion of prostate can be rem.oved as a part of the procedure. The after-care consists in irrigation and repacking of the lower wound as is necessary. The opening of the bowel is delayed for sev- eral days so as to avoid infection of the abdominal wound. In cases, where necessary, a large drainage tube may be sewn into the bowel and the free end placed in a bottle so that the discharge is collected without soiling the wound. The extra portion of bowel, one and a half to two inches, project- ing above the skin can be cut down to the level of the skin at any time without anaesthesia. We believe the leaving of this for several days to be an excellent plan because sloughing of some of the bowel occasionally takes place and then the opening is brought too close to the skin line. After recovery the patient is fitted with our permanent colostomy cup which enables him to go about his business without fear of soil- ing his clothing and without the presence of disagreeable odors. This operation, which has given in our hands an immunity of over eight years in one case, and others still free of recurrence at vari- ous periods over two years, with no mortality in the last eight cases and with comparative comfort to all during those years, strongly appeals to us when we recall the sufferers we have seen in the later stages of the disease. These poor sufferers are in a deplorable con- dition, reduced to mere skeletons, suffering intense agony, with con- stant tenesmus and a continuous foul rectal discharge. The odor is so offensive that they are avoided by their families. Their condition is worse than death. Let us make every effort to reach these people early and save them this miserable existence. 96 IX SAINT MARY'S HOSPITAL. GASTROJEJUNOSTOMY WITH CLOSURE OF THE DUO- DENUM AND CHOLECYSTOSTOMY. Onslow A. Gordon, M.D., F.A.C.S., THE case here reported is considered worthy of record because of the fact that the pylorus having been closed by a simple method remains impervious at the end of sixteen months. The patient, thirty-nine years old, referred to me by Dr. M. L. Bodkin, had suffered from "indigestion" for about two years. She complained of pain in the epigastric region often associated with nausea and vomiting. The pain was usually relieved by taking food and alkalies. Her vomiting usually occurred about two hours after meals and was as a rule sour and burning. She had on two occasions vomited almost clear blood and had noticed blood in her stools. Dur- ing the past year she had lost forty pounds. With this classical his- tory and physical and laboratory findings substantiating it, the diagnosis was apparent. She was operated on June 4, 19 15. The patihiology found at operation was an indurated ulcer just to the gas- tric side of the pylorus and a gall-bladder containing several calculi. The ulcer was treated by a posterior gastrojejunostomy with exclusion of the pylorus. The gall-bladder was drained after the usual manner. The interest in this case of course centers in the subject of exclusion of the pylorus. The advisability of closure of the duodenum has not been definitely established and advocates of this procedure are not at all agreed as to the most desirable method. In this case the pylorus was closed by the simple method advocated by Berg. A heavy linen purse- string suture was carried around the posterior stomach wall at the pylorus and then tied, thus closing off the duodenum. This closure has remained permanent up to the present time, a period of six- teen months, as shown by radiographs. The patient made an uneventful and complete recovery and since operation has gained about fifty pounds in weight and apparently is in perfect health. 99 X THE PILCHER PRIVATE HOSPITAL. PAIN DUE TO ANATOMICAL DEVIATION OF THE URETER. Paul Monroe Pilcher, A.M., M.D. TO determine the cause of pain referred to the abdomen or to the back is often a difficult problem. When the pain comes on unexpectedly in the night without a previous history of some definite disorder, we think of many lesions which might give rise to it. The occurrence of nausea, vomiting and frequency of urina- tion is so common an accompaniment of most attacks of colicky pain that they often simply tend to confuse the picture. In our search for evidence we palpate the abdomen; we examine the urine and blood ; we take the temperature ; we examine the pelvis ; we take radiographs, and when all is done we may be still in doubt. However, there are still more delicate tests which may be employed. They consist of a combination of special methods and instruments. I refer to the stomach tube, the Bismuth meal, the Bis- muth enema and the x-ray in stomach and intestinal lesions ; the blood test for cholesterol, urinary analysis, and the x-ray for gall stones; and the cystoscope, the ureter catheter, the x-ray and pyelog- raphy in obscure lesions of the kidney, kidney pelvis and ureter. Add to these a mind trained to interpret these combined findings and a correct diagnosis is the result, where fonnerly an exploratory opera- tion was resorted to, and only too often failed to reveal the lesion. During the past year several cases have been referred to our clinic complaining of recurring pain in the hypochondrium and lum- bar region, often extending downward to the lower right or left abdominal region. Those patients in whom pus or macroscopic blood, or tubercle bacilli have been found in the urine coming from the ureter of the affected side, have been relatively easy of diagnosis, es- pecially when a radiograph has shown the presence of a calculus at the pelvo-ureter junction, or in the ureter. In most of the remaining cases, gall bladder disease, ulcers of the stomach and intestines — aneurysms — spinal disease — and tubo ovarian and uterine lesions can be excluded as the cause of the pain. There remain chiefly the chronic lesions arising from the ap- pendix and a condition frequently mistaken for appendicitis, namely intermittent dilatation of the renal pelvis due to anatomical deviation of the ureter, and a small class of cases due to stricture of the ureter and perinephritis. The acute inflammatory lesions are not easily con- fused with any of these disorders. The cases of anatomical deviation of the ureter include chiefly those due to high implantation of the ureter into the renal pelvis, twists and kinks of the ureter due to undue mobility of the kidney and the first portion of the ureter, and the very important class of cases in which a set of aberrant blood vessels cross the ureter and enter the lower pole of the kidney and form a loop over which the ureter bends and becomes obstructed. 103 The diagnosis of such a condition can be made before operation with considerable exactness ; but oftentimes it involves an extended study of the case, and even when it is suspected after taking the his- tory, examination may lead to the discovery of other lesions as a cause of the pain. The possibilities of diagnosis and the means employed to establish the same are well shown in the following case reports : Ii^i^usTRATivE Cases. Case I. Clinic No. 1,976. Referred by Dr. H. M. LowenthaL Diagnosis: Intermittent hydro-pelvo-nephrosis ; obstruction of ureter due to aberrant blood vessels with kink and twist of ureter. Chief Symptoms: Recurrent pain in right hypochondrium and the right lower quadrant of the abdomen. Patient is a young nervous girl, aged 23, who seven years ago began to have pain in the right side coming on in the evening and lasting for about two hours. If she worked too hard, or was very nervous, pain would appear in the right hypochondrium. It would come on sharply and would disappear suddenly. Latterly the pain has been more severe and she has needed some morphine to control it. There has been no disturbance of any of the essential systems of the body. Her nutrition is good and the bowels are regular. There are no symptoms referable to the stomach or lungs. No bladder symptoms. Pain always starts in the same spot in the right hypo- chondrium with severe colic-like pain which passes through to the back, very similar to that observed in gall stone colic. After the sever- ity of the pain has passed, the soreness remains and feels like a sore tooth. Pain is more apt to come on when she is tired, but does not seem to have direct connection with exercise, and no connection with eating, gas formation in the bowels, or her menstrual periods. After awhile the pain goes away and she passes an increased amount of water, or at least she goes more frequently to pass her water. Lately the pain has been more severe. She has an attack every two or three weeks. Two weeks ago had an attack which lasted all day and into the next day. At first there is a gnawing feeling in the right side and sense of pressure, then developes severe colic, and now there is a continual sense of distress in that side. The condition has repeatedly been diagnosed as appendicitis and she has repeatedly been advised to have her appendix removed but the operation has been refused. Physical examination showed no abnormahties with the exception that the right upper quadrant of the abdomen examined during the time the patient was having pain, showed the presence of a fairly large mass in the region of the kidney and gall bladder presenting beneath the free border of the ribs. There is some tenderness over the cecum. Examination of the urine — acid, 1020, no albumin, no sugar and no abnormal microscopical findings. From the history of the case, the age of the patient, the peculiar character of the attacks, the long duration of the attacks, the ab- sence of urinary findings, the absence of any gastro-intestinal dis- of various types, the most probable diagnosis in this case is an inter- turbance, such as excessive fermentation, constipation and indigestion mittent hydro pelvo renalis, due to anatomical deviation of the ureter 104 1 Fig 1. Uretero-pyelogram in Case 1. Showing de- formity of ureter and "egg shaped" dilatation of renal pelvis. Pilcher Clinic. Fig. 2. Outlines of kidney and ureter in Case 1. Note oblique axis of kidne}^ Uretero-pyelo- gram. Fig. 3. Artist's interpretation of the pyelograph in Case 1. Pilcher Clinic. Fig. 4. Dilated renal pelvis due to anatomical deviation of ureter (aber- rant blood vessel). Incision exposing kidney showing dilated pelvis present- ing in w^ound. Case 1. Fig. 5. Dilated renal pelvis showing aberrant blood vessels crossing ureter causing constriction. Showing position of hand grasping kidney to accentuate deformity. Aberrant vessels (Ab) have already been cut — consisting of an ar- tery and two veins entering lower pole of kidney. Case 1. Fig. 6. Dilated renal pelvis due to anatomical deviation of ureter. Later step in operation after blood vessels have been divided and dissected free from ureter. In 'cases of long standing a permanent impression has been made upon the ureter with thickening. The probe should be passed from above downv/ard beyond point of obstruction and a suitable size soft bougie passed from above into the bladder. Fig. 7. Pyelograph of the ureter and renal pelvis in Case 2. caused either by an aberrant blood vessel or a fixed portion of the ure- ter kinked by prolapse of the kidney. In a case of this kind we can exclude chronic appendicitis and prolapsed or enlarged twisted cecum, on account of a definite lack of intestinal symptoms. Stone in the kidney is also possible, but may be excluded by x-ray examination. But a stone present in the pelvis or right ureter for a period of seven years would give absolute changes in the urine, which we did not find in this case. The indications for the examination are — first, an x-ray of the kid- ney and second, a pyelograph of the pelvis of the kidney. Further examination was made on October 21, 1915. Radiograph taken by Dr. James Pilcher showed right kidney to be normal in size, but its axis was oblique. There was no stone present in the kidney, or its pelvis, or its ureter. Argentide picture of the right ureter and kidney showed the right ureter to be normal in size until it reached a point opposite the transverse process of the first lumbar vertebra, where it is constricted and twisted about. The argentide, hov/ever, passes by the obstruc- tion and dilates the kidney so that the picture is that of a typical egg- shaped pelvis which is pathognomonic of an intermittent hydro-pelvo- renalis, due to constriction or aberrant blood vessels. (Figs. 1, 2, 3.) In examining the pyelographs it will be seen that none of the calyces are visible and this is so because the relaxed walls of the hydronephrotic sac are not distended to their full capacity. The kid- ney itself lies between the free border of the ribs and the crest of the ilium. Cysioscopic examination revealed the fact that the left kidney was present and secreting normal urine. Operation, exposing right kidney (Fig. 4). It was found pro- lapsed and in an oblique position wnth a dilated pelvis. A set of aber- rant vessels was found crossing the ureter, as indicated in the radio- gram, consisting of a fairly large artery and two veins, as in the accompanying drawings. The artery was ligated and divided and in addition was dissected away from the ureter. (Fig. 5) It was found that there was some constriction of the ureter beneath this attached vessel. The pelvis which was greatly dilated was separated, a large probe passed down through the ureter dilating it. (Fig. 6) A plastic operation on the pelvis of kidney was done; the kidney fixed in normal position and the wound sutured. Patient made an uneventful recovery and has never had any re- currence of symptoms since that time. Cask II. Male. Referred by Dr. Warren L,. Duffield. Diagnosis: Intermittent hydro-pelvo-nephrosis ; obstruction of ureter due to aber- rant blood vessels causing kinking of ureter. Abstract of History: Patient nineteen years of age. Six years ago began to have attacks of pain in region of right kidney, not very- severe, radiating to testicle and bladder. Lasting about two days. Attack comes on gradually, becomes more severe, dull ache and then disappears. These spells come on at least every two weeks, and are described as attacks of severe cramplike pain in the right side beneath the free border of the ribs, frequently brought on by violent exercise, riding on trains, etc. Generally comes on in the middle of the night. His urine has been examined by several physicians who stated that he had pyelitis. Aside from the pain there have been no symptoms of 105 renal disease. Bowels regular ; no indigestion ; sleeps well, but nervous. This is practically all of his history. In other words, he has recurrent attacks of pain in the right hypochondrium referred to the right lumbar region, extending down toward the bladder. The region of the kidney is tender during these attacks. The patient is becoming more and more limited in his activities. Urine Acid; 1018; trace of albumin; small amount of blood; many large round epithelial cells and crystals. Cystoscopy: Urine collected from right kidney showed many blood cells, probably traumatic ; large number of granular and renal epithelia. X-ray of kidney negative. Argument: By exclusion, all of the more common lesions were eliminated. Our only positive signs were the few blood cells in the urine and pain in the region of the right kidney, for the x-ray picture was negative. Therefore, a pyelograph of the right kidney and ureter was taken and showed that the right ureter was very markedly kinked, forming a hairpin curve opposite the pelvis of the kidney, and that it entered the pelvis of the kidney abruptly. A second picture showed an egg-shaped dilatation of the pelvis of the kidney (Fig. 7). On this evidence a diagnosis was made of intermittent dilatation of the renal pelvis due to obstruction of the ureter caused by aberrant renal blood vessels. Operation was advised and undertaken by Dr. Duffield. The exact anatomical conditions as outlined in the argument were found by him at operation. The blood vessels were divided and the ureter which had been very markedly kinked immediately straightened out. The kidney was fixed in a high position and the patient made a good recovery. Cass III. Male. Referred by Dr. Arthur H. Bogart. Diagnosis: Intermittent hydro-pelvo-renalis due to anatomical deviation of the ureter. Patient twenty-two years of age. Main points in history were that the patient had suffered from attacks of pain referred to the right side of the abdomen mostly in the lumbar region. First attack came on suddenly in the middle of the night, in February, 1914, very severe and suggestive of renal origin. There was frequency of urination. Second attack ten months later came on during the day. Pain started in the back and radiated to the front. At first the pain was severe, then moderated. There was increasing frequency of urination. X-ray examination negative. Several attacks followed. Was in hospital for three weeks under observation, as the result of which he was oper- ated upon for possible appendicitis, and a kinked, diseased appendix was removed. However, attacks recurred immediately. Further x-rays, wax tipped catheters and many examinations at another clinic failed to reveal the cause of his symptoms. A study, however, of the x-ray plates demonstrated that the kidney occupied an oblique posi- tion; that its axis was not perpendicular which it should be in the normal state; also that the kidney descended through an arc of fully two inches and that the hepatic flexure of the colon was prolapsed. Further, that there occurred regularly a spasm at the hepatic flexure (Fig. 8), which would account for pain in the region of the cecum. A pyelogram of the right kidney (Fig. 9), was taken under anesthesia and it revealed an irregular dilatation of the pelvis of the 106 Fig. 8. Radiogram of cecum and hepatic flexure in Case 3. Showing spasm of section of gut at flexure. Appearing on several plates. Fig. 9. Outlined pyelogram of kidney in Case Fig. 10. (2096j Reproduction of x-ray taken in Case 3 at Dr. Eastmond's Clinic showing pro- lapse of hepatic flexure, pro- lapse of right kidney and change in the kidney axis. Dotted line A is the normal axis of the kid- ney. Dotted line B is the axis of the kidney shown in the x-ra3\ [^liH^^^ Fig. 11. Pyelogram in Case 5. Showing normal ureter and kidney pelvis. right kidney with the calyces of the kidney moderately dilated. A positive diagnosis of intermittent dilatation of the pelvis of the kidney with anatomical deviation of the ureter was made. Previous to this time pain had centered more over the region of the appendix and low down in the pelvis. Argument: The symptoms in this case were very severe first, pain in the region of the kidney, later most marked over the cecum; some frequency of urination during attacks; a few blood cells in the urine; some rigidity of the right rectus muscle during these attacks. The patient was operated upon by Dr. Bogart. A moderate dilatation of the pelvis of the kidne ywas found. The kidney was sutured in a high position. No aberrant blood vessel demonstrated. Patient made a good recovery and has been well since that time. Case IV. Female. Referred by Dr. Walter D. L,udlum. Diagnosis: Intermittent dilatation of pelvis of kidney due to kink- ing of ureter in a case of ren mobilis. Partial volvulus of ascending colon. Some cases are complicated by intestinal lesions. It is very im- portant to search these out in order to do complete surgery when any- thing is attempted. This patient complained of pain in the right hypo- chondrium and the right lumber region, quite typical of renal disturb- ance. These attacks were severe and recurrent, passing down to the region of the cecum. The attacks of pain in the right side came on at intervals of months, but there were no evidences of disease demonstra- ble in the urine. In addition, she gave a very distinct history of in- digestion supposed to be due to gastric ulcer; was persistently con- stipated. Radiogram showed the presence of a rudimentary rib, a prolapse of the hepatic flexure and prolapse of the right kidney. A pyelograin showed a very slight dilatation of the pelvis of the right kidney, but no change in the calyces of the kidney. Negative for stone. Cystoscopic examination showed an accumulation of urine in the pelvis of the right kidney. Argument: A case with such a history demands more than a diagnosis of intermittent dilatation of the renal pelvis, and further examination revealed a prolapsed dilated cecum. Operation was undertaken. The kidney was found to be prolapsed and freely movable. It was raised up and fixed in good position. Then the abdomen was opened through a right rectus incision. A prolapsed and partially rotated cecum was found together with a markedly dilated caput with a long appendix. A plastic operation was done on the cecum, and the ascending colon was brought up into its normal position and sutured there. As a result, the patient made a good recovery and was relieved of her lumbar and lower abdominal pain. There are now no symptoms of her original indigestion and her bowels move regularly without cathartics. Case; V. Patient presenting symptoms similar to those found in cases of intermittent dilatation of the renal pelvis due to anatomical deviation of the ureter, hut really due to conditions of the colon and pelvic organs. A woman, twenty-four years of age, whose chief symp- tom had been persistent pain in the left hypochondrium passing around to the back and down toward the bladder. She stated that the 107 pain came on suddenly and v/as described as a general abdominal pain which later resolved itself into a colicky pain referred to the left hypochondrium and left lumbar region. She usually vomited with these attacks and demanded morphin to control the pain. The attacks recurred with increasing frequency. Was sent to another clinic and remained there for two months without diagnosis and returned home still suffering from the pain. The chief features of her illness while in the hospital were vomiting and pain. The diagnosis first suggested by the symptom complex was an ob- struction of the ureter with pain originating in the kidney. Urinalysis showed an acid reaction, sp. gr. 1.020, trace of albumin, no sediment. Radiographs of the kidney were negative. Vaginal examination showed tenderness in the left fornix. Trac- tion on the cervix caused pain referred to left hypochondrium. Radiographs of the colon demonstrated a deformity of the cecum and transverse colon, confining a fecal mass in the cecum; also show- ing the presence of adhesive bands binding together a portion of the transverse colon and ascending colon. A pyelogram of the left kidney and ureter was taken and no ab- normality was found. (Fig. 11.) Evidently the kidney must be excluded as the cause of the pain. With the definite lesions known to exist in' the first portions of the large intestine, the patient was again questioned as to her early his- tory, and it developed that at first she had suffered entirely from pain on the right side. This pain had come on suddenly, was accom- panied by vomiting and fever and was very suggestive of acute ap- pendicitis. The left sided pain evidently originated in the left tube and ovary. The abdomen was opened and a chronically deformed appendix was removed. The ascending and transverse colon v^^ere freed from the adhesions which bound them together. A plastic operation was per- formed on the left uterine adnexa and some adhesions extending to the sigmoid colon were divided. The patient made a good recovery and has been entirely relieved of her symptoms. In concluding this brief clinical report the writer wishes to em- phasize the fact that the diagnosis of pain due to anatomical deviation of the ureter can rarely be made from a consideration of the clinical symptoms alone, or by the aid of examinations made in the laboratory. One must depend more upon the various mechanical aids, such as the pyelograph and the cystoscope, basing our final judgment, how- ever, on the combined evidence collected from interrogation of the patient, a personal examination of the patient, the laboratory reports, and the interpretation of the scientific aids to our special senses, the cystoscope and the x-ray. 108 COLUMBIA UNIVERSITY LIBRARIES This book is due on the date indicated below, or at the expiration of a definite period after the date of borrowing, as provided by the library rules or by special arrangement with the Librarian in charge. DATE BORROWED DATE DUE DATE BORROWED DATE DUE 1 - 1 C28(842)MSO RDll Sureical olinics and clinioal Su7 COLUMBIA UNIVERSITY LIBRARIES (hsi.stx) RD11SU7C.1 Surgical riHiirs ,-inf! rhmrai iHjKiiism 2002105101