'^^^nx \^'^^ ffinlumbta Hntu^mtg in tl|r flittg 0f N^m f nrk IJfffrpttrp Cibrarg .ait' LECTUR ON THE TREATflENT OF FIBROID TUMORS OF THE UTERUS Medical, Electrical and Surgical. BY FRANKLIN H. MARTIN, M.D. prokessor of gynecology post-graduate medical school of chicago; siir(;eon woman's hospital of Chicago; gynecologist Chicago CHARITY hospital AND THE POST-GRADUATE HOSPITAL; CHAIRMAN SECTION OF OBSTETRICS AND DISEASES OF WOMEN OF THE AMERICAN MEDICAL ASSOCIA- TION (1895); PRESIDENT CHICA(;<> GYNECOLOGICAL SOCIETY (1895); ETC., ETC. AUTHOR OF ELECTRICITY IN OBSTETRICS AND GYNECOLOGY. THE F. A. DAVIS COMPANY, PUBLISHERS. PHILADELPHIA. - NEW YORK. - CHICAGO. 1897. ^- COPYRIGHT ACCORDING TO ACT OF CONGRESS BY FRANKLIN H. MARTIN, M.D. #• - PREFACE. It was the lot of the writer of these lectures to have entered J the practice of gynecology at the dawn of antiseptic surgery. ^ With the possibilities revealed by this great advance, for fifteen years, the surgeons of civilization have been struggling toward perfection. In a little more than a decade wonders have been accomplished and surgery developed to a science. During this period of unprecedented activity the treatment of fibroids of the uterus has received a large share of attention and may now be said to have reached as high state of perfection as any other branch of surgery. The benign nature of these tumors, their slow development, their small mortality without treatment made patients reluctant to accept the radical operations. Hence minor medical and surgical means were sought and persistently cultivated to the limits of their possibilities, Krgot, electricity, the Battey-Tait operation and ligation of the broad ligaments are minor treatments which have relieved much suffering, cured not a few patients, and saved many from the more dangerous procedure of hysterectomy. In the devel- opment of these minor means, not only, but in the cultivation and improvement of the major surgical technique the writer has devoted a greater portion of his professional time for the last ten years. The object of these lectures is to place in per- manent shape the outcome of this decade of work and to place in the hands of his friends and students a mirror, as it appears to him, of the present status of the treatment of fibroids of the uterus. FRANKLIN H, MARTIN, M,D. September 1, 1896. LECTURE I. Anatomy, Histology, Varieties, Etiology, Degen- eration, Spontaneous Disappearance, Etc. The designation, •' Fibroid Tumors of the Uterus, " which is employed throughout this work, is used for convenience, euphony, and because it has become the established and accepted term in America, for all myomatous or fibromatous enlargements of the uterus. These enlargements are also called: Myoma or Fibromyoma Uteri; Fibrous Tumors; Tumeur Fi- breuse ; Myofibroma Uteri; and Hysteroma and Mus- cular Tumors of the Uterus. gross anatomy. Fibroid tumors of the uterus vary in size from a scarcely perceptible enlargement of the uterus, to a tumor which may weigh more than one hundred pounds. No definite limit of maximum dimension can be assigned; some grow rapidly to an enormous size, while others, under apparently the same condi- tions, increase slowly and never attain such propor- tions as to produce deformity. The gross appearance of fibroids of the uterus differs as widely as does their size. There is no accounting for the great variety of shapes assumed by these benign growths. Each one is a law unto itself. For convenience we divide them according to their method of development, which influences their contour, into: 1. Interstitial. 2. Intramural. 3. Subperitoneal. 4. Submucous. An Interstitial Fibroid is one in which the new growth is uniformly distributed throughout the body of the uterus, without any large, distinct nuclei of development. The external appearance of such a fibroid is that of a symmetrically enlarged uterus, without external nodular enlargements, or without irregular projections of a submucous nature into the cavity of that organ. These symmetrical tumors often grow to weigh many pounds, and frequently enlarge the cavity of the uterus until it will measure many inches in depth, proportionately increasing the area of the endometrium. I have examined such cases where the uterine canal measured fourteen inches in depth. Intramural Fibroids are those in which the new tissue is confined to the walls proper of the uterus, but in which several distinct centers of development are apparent to the naked eye. While each center may possess several nuclei, the manner of growth is not uniform throughout the uterine walls. This variety makes the uterus irregular and the direction of the canal uncertain. The separate distinct centers of development, as felt through the uterine tissue, are much firmer and less elastic than the new tissue, which makes the typical interstitial variety. Its out surface frequently exhibits to the naked eye, white cartilaginous centers surrounded by loose connective tissue; these centers are often easily enucleated from the muscular tissue of the walls of the uterus. From the standpoint of gross anatomy this variety is distinct and unique. The intramural fibroid is much less liable to develop into very large tumors, because of their tendency to become pedunculated. A subperitoneal Fibroid is one which grows from one or more centers of development, which may become pedunculated, and projects from the walls of the uterus into the peritoneal cavity. The gross appearance of these projections when cut through is that of the intramural variety. A Submucous Fibroid is one which grows from one or more centers of development and projects from the walls of the uterus into its cavity. This variety resembles the intramural in its gross appear- ance. It may become pedunculated and then becomes an uterine polypus. I make the unusual distinction between interstitial and intramural fibroids, not only on account of anatomic reasons, but from a therapeutic and surgical standpoint, since their action under the influence of ergot, electricity and the knife is strikingly different. In the examination of an unusual number of fibroids, I can approximate the relative percentage of the occurrence of the several varieties as follows: Interstitial 55 per cent., subperitoneal 20 per cent., intramural 15 per cent., submucous 10 per cent. HISTOLOGIC CHANGES. Fibromata. — Fibroid tumors of the uterus are rarely fibromata; they are less rarely a mixture of fibromata and myomata; while in a large majority of cases they are pure myomata. According to Bland Sutton, ''typ- ical fibromata are generally dense tumors consisting of wavy bundles of fibrous tissue. The bundles are composed of long slender fusiform cells closely packed together. The tissue of the tumors, often arranged in whorls, is permeated by blood vessels." This same writer says: "The difficulty of distinguishing between a myoma, a slowly-growing spindle-celled sarcoma and a pure fibroma is well known to skilled histologists." Myomata are tumors composed of unstriped muscle fibers. Myomata are composed of long fusiform cells with a rod-like nucleus; the size of the cells vary greatly in different tumors. The bundles of muscle fibers are often interwoven in such a manner that the cut surface presents a characteristic whorled appearance. (Bland Sutton.) The well-developed tumor consists of unstriped muscle fibers mixed with more or less fibrous connective tissue and fusiform cells. (Garri- 8 gLies.) According to Pozzi, on microscopic section fibromata (fibro-myomata) present smooth muscular fibers and connective tissue in varying proportions. Blood Vessels. — The vascularity of fibroid tumors varies greatly. Hard fibroids composed of an unusual amount of fibrous material constituted in the main of long fusiform cells, closely packed together, contain smaller and fewer vessels than the soft or myomatous tumors, composed of unstriped muscular tissue- fibers more loosely packed. The latter are frequently very vascular, the blood vessels being easily traced into their interior. The former are often surrounded with a loose fibrous capsule which frequently contains a free distribution of blood vessels, from which the tumor proper draws its nourishment. The moderately vascular are slow in growth while the soft vascular tumors develop rapidly. " The vessels that traverse these soft tumors are often of larger size," says Sutton, "especially the veins, and furnish a loud systolic bruit on auscultation." '• Some of these myomata are so richly furnished with blood vessels that on transverse section they look not unlike erectile tumors. Indeed Virchow speaks of them as 'cavernous or telangiectatic myomata.'' The vessels seen on the cut surface are for the most part veins. Many excellent examples of the extreme vascularity of such tumors may be found, and it may easily be conceived that under varying conditions, such tumors would alter in size, and in some cases this has been so marked that the tumor seemed to be erectile." (Bland Sutton.) Winkle says: " Ordinarily these tumors are not very vascular but in exceptional cases, not only the adjacent tissues, but the tumor itself contains a great numV^er of large vessels." Nerves. — According to good authority nerves have been traced into the substance of fibro-myomata. According to Winkle, Astruc asserted that he found them in the parenchyma of a polypus, and Bidder, in a large fibroid, once found a nerve fiber Hartz described them and their method of termination in the nuclei of the smooth muscular fibers. Dupuy- tren also traced nerve fibers into these growths. Lymphatics. — Fibroids of the uterus contain lym- phatics. Conclusions. — In the proportion that the histology of a fibroid tumor approaches in microscopic struc- ture fibromata^ does it increase in density, become less vascular, has a more definite capsule, is less intimately connected with the muscular tissue of the uterus, is of much slower growth and is much more liable to be of the intramural variety. In the proportion that the histology of a fibroid tumor approaches in microscopic structure, myomata. does it decrease in density, become softer and more vascular, is its capsule more indefinite because the new growth is more intimately distributed with the the muscular structure of the uterus, is of more rapid growth and is much more liable to be of the interstitial variety. DEGENERATIVE CHANGES. Fihrocysts. — Mucoid Degeneration. — According to Bland Sutton large uterine myomata are especially prone to undergo a change, whereby large tracts of the tumor substance soften and become transformed into mucin. When this takes place extensively the tumor is converted into a spurious cyst. He adds that the degeneration is preceded by edema of the connective tissue and that the cells assume the characteristic spider-like form to which the term myxoma is applied. Virchow says this myxomatous degeneration is characterized by an effusion of mucous fluid among the muscular bands, and that it is dis- tinguished from simple edema by the presence of mucin and the multiplication of the nuclei and small cells. When the bands between the small round cells and the edema disappear, small fluid collections exist which form the spurious fibrocysts. The true fibrocysts, according to Pozzi, have a very 10 different origin. " These cysts are formed in pre- existing cavities, in dilated lymj)li spaces comparable to the similar dilatations which the blood vessels pre- sent. The fluid which they contain is limpid and coagulates on contact with the air. Leopold has termed these tumors 'lymph angiectatic myoma.' It must be noted that this lymphatic origin of certain cystic tumors of the uterus had already been clearly formulated by Koeberle. This formation seems to be due to the development of part of the tumor along the path of the lymph vessels contained in the broad ligament. On the internal surface of such tumors we can demonstrate an epithelial investment which distinguishes them from simple cavities formed from softening of the neoplasm or apojolexy into its substance. There are also mixed forms in part vascular and in part lymphatic." Induration. — Fibroids contract, reduce and harden as a rule following the menopause, while occasionally they disappear entirely. The same change takes place after confinement, in myomata of the fundus of the uterus which complicates pregnancy. The change resembles much that occurs in a fibroid after the removal of the appendages. The cause of the change, in each instance, is doubtless due, to a lessening of the blood supply. Fatty Degeneration. — Literature does not record many well authenticated cases of fatty degeneration of fibroids. That it does occasionally occur, there is lit- tle doubt, although so rarely that from a clinical 8tandi)oint it is of little value. Calcareous Degeneration.— 0\di uterine myomata, both large and small, are liable to become infiltrated with earthy matter. The change only occurs in slow growing tumors containing a large proportion of fibrous tissue. The calcareous material is not deposited in an irregular manner in the tissues of the tumor, but corresponds to the disposition of the fibers; on exam- ining the sawn surface of a completely^ calcified uterine myoma we find the whorled disposition of the 11 fibers so completely reproduced as to leave no doubt as to the nature of the mass. When these calcified tumors are macerated and the decayed tissues washed away, the earthy matter retains the shape of the tumor, but its exterior presents an irregular, porous, almost worm-eaten appearance. The calcification is confined to the tumor itself, and though we may occasionally find isolated nodules of earthy matter dotted about the capsule, this part of the tumor is not converted into a hard resisting shell. Suppuration. — Suppurating fibroids may be fibroid enlargements of any variety which by some accident have become infected. Fortunately it is a condition which occurs but rarely. Occasionally a subperitoneal fibroid, which in process of pedunculation has been deprived of a portion of its blood su^Dply, by a grad- ual narrowing of the pedicle, may become infected by migration of microbes through the walls of an adjacent intestine upon which pressure has been long main- tained. An interstitial fibroid may be converted, in rare instances, into a suppurating mass through infec- tion, by direct continuity, from a suppurating endo- metritis. Submucous polypi, of low vitality and small resistance to pathogenic microbes, quite often are infected from the endometrium and the vaginal secre- tions, and suppurate,resulting in an offensive discharge of pus, and occasionally, hemorrhages — all of which may give rise to a suspicion of malignant disease of the uterus. Carcinomatous Degeneration. — I have had an opportunity of examining and having under observa- tion, for long periods, an unusually large number of fibroid tumors of the uterus, and I have never known one to undergo carcinomatous degeneration. My experience coincides with that of the best authorities on this subject. Fibroid tumors do not predisjDose to carcinomatous degeneration. Cancerous changes may occur, however, in a fibroid uterus as a coincidental disease, but in no way as a direct result of the fibroid. Spontaneous Disappearance. — Almost every author- 12 ity who has watched the course of many fibroid tumors of the uterus, has witnessed the spontaneous disappearance of one or more of these growths, with- out any apparent cause. Gusserow at one time suc- ceeded in gathering from literature thirty cases in which this undoubtedly occurred. Of these thirty, thirteen were associated with pregnancy, while the majority of the remainder were connected with the menopause. It is not difficult to explain the disap- pearance of a fibroid which has been coincidental with pregnancy; the process of involution of the uterus which occurs after confinement, is imparted to the myoma, which so nearly resembles the uterine tissue, and the tumor, consequently, is greatly diminished, or disappears altogether. Then too, the decrease of the blood suiDi)ly to the uterus, as involution takes place, deprives the tumor of its accustomed nourish- ment, and thus causes its diminution. The reduction in size, or disappearance of a fibroid at the menopause may be accounted for on the theory of diminished blood supply, and consequent starva- tion. When senile atrophy begins in the organs of the pelvis, and m^enstruation ceases, with consequent decrease in the requirements of blood supply, the uterus atrophies, and necessarily a tumor dependent upon that organ for nourishment, must also suffer anenda and reduction in growth. But, occasionally, fibroids of the interstitial variety will suddenly and mysteriously disappear, without any apparent cause. 1 know of one which decreased in size, fully two-thirds, as the result of a simple exjjloratory operation. These tumors may also be spontaneously expelled by: 1, Pedunculation — a gradual narrowing and length- ening of the pedicle, until by violence or suppuration the stem separates. This may occur with either a subj^eritoneal or a submucous i)olypus. 2. Enucleation — This may occur with a submucous or an intramural of the hard variety (fibromata) 13 which is usually surrounded with a loose capsule, and which at its nearest approach to the mucous mem brane becomes infected. The suppuration will grad- ually encircle the mass, and by means of uterine con- traction, the tumor will slowly be shelled from its bed and expelled from the uterus. 3. Suppuration. — Spontaneous disappearance of fibroids occurs as the result of suppuration following infection. ETIOLOGY. Pathologists have been unable to satisfactorily dem- onstrate the causes for the development of fibroids of the uterus. Pozzi says of Velpeau's theory, attributing the development of fibroids to the presence of a blood clot in the uterine tissue: "The spontaneous organi- zation of coagula after ligation of the arteries sug- gested the idea that the same process might result in the formation of these neoplasms. But experimental study has demonstrated that this organization of coag- ula is nothing but an ingrowth of the elements of the vessel's wall and thus this edifice of theor}^ founded on lack of observation, collapses altogether. "Klebs asserts (Pozzi) that these tumors have their origin in a proliferation of the connective tissue and muscular layers of certain vessels ; the different nod- ules thus formed become aggregated to make one tumor. Kleinwachter describes the evolution of fibro- mata as due to a round cell which is found along the capillaries and produces a partial obliteration of them; these cells then become fusiform and produce nod- ules. In other words, our knowledge of the subject is still very imperfect." Winkle, without any clear demonstration or expla- nation, attributes the dependence of these growths to the peculiarities of the vessels of the uterus, in that the arteries are subjected to a very high pressure before they reach the uterine wall, notwithstanding their convoluted course 14 Senn believes in Cohnheim's theory of tumor devel- opment as modified by himself, viz.: That tumors never develop from mature tissue but from a matrix of embryonic tissue. According to Senn this matrix of embryonic tissue may be either of pre- or post-natal origin. "A fibroid," he says, "in the majority of cases springs, no doubt, from a matrix of mesoblast in the uterine tissue, while in exceptional cases the tumor may start from a similar matrix in the wall of blood vessels.'* AGE AND DOMESTIC CONDITION AS PREDISPOSING CAUSES. Fibroids seldom occur before puberty. In 575 autopsies upon females by Winkle, 12 per cent, had these developments. Of 135 examined in the dead house by him, under 35 years of age, only 5 per cent, had fibroids. Dr. Emmet, who has made a most careful study of this subject, basing his opinion on recorded cases, says: "It is impossible to determine with accuracy the age at which these growths are most likely to appear, since their development is, as a rule, slow at first, and they may exist for an indefinite period before their presence is recognized. The age can only be approximately inferred from the average one at which professional advice was first sought, and this would seldom be before the tumor had reached a suffi- cient size to cause hemorrhage or some other disturb- ance. We may also gain some information as to the rapidity of growth from the length of time elapsing after the birth of the last child, for a fibroid, it is well known is a cause of sterility. In the table is shown the age at which 225 women, who had fibroid growths, were first examined. The earliest age was 18, an unmarried woman; the next a sterile woman at the age of 22; 1 at 23; 10 between the ages of 24 and 25." His table then gives 25 cases between the ages of 25 and 30; 50 cases between the ages of 30 and 35; 48 cases between the ages of 35 and 40; 42 cases between 15 the ages of 40 and 45; 25 cases between the ages of 45 and 50; 8 cases between the ages of 50 and 55; and 5 cases between the ages 55 and 60. Thus accord- ing to this table, which corresponds closely with the experience of other writers, the age of greatest liabil- ity to fibroids is shown to be between 30 and 35 years. According to Emmet, based upon statistical tables, •'between the ages of 30 and 40 years the unmarried woman is fully twice as subject to fibrous tumors as the sterile or as the fruitful;" he adds, "It seems as if it were the purpose of nature that the uterus should undergo the changes dependent upon pregnancy and lactation about three years throughout the childbear- ing period, and that if the uterus is not physiolog- ically occupied in childbearing, a fibroid will the more rapidly develop. . . . This will also be the case with the married woman who has taken means to prevent conception, as well as with her who has been sterile from some cause beyond her control, but to a less degree in the latter case. . . . Finally, the woman who may have been fruitful in early life, but remained sterile long afterward from some accidental cause, may have a tumor developed, but is less liable thereto from having once borne a child." Brooks Wells says: "Myomata of the uterus are more common in old maids than in married women." This statement is often disputed by gynecologists who do not frequent the dead house. Very many exam- ples of myomata appear postmortem whose presence was not even suspected during life. Race. — It is an undeniable fact that the negro women, with the environments of this country, are more liable to have fibroids of the uterus than white women. This statement is doubted by Dr. Middleton Mitchel, of Charleston, S. 0. I can not but believe, however, that Mitchel is wrong, espec- ially as far as the negro women living in the northern and colder latitudes of the country are concerned. 16 SUMMARY. The cause of fibroid tumors of the uterus has never been satisfactorily demonstrated. Fibroids of the uterus rarely occur before puberty, and seldom before the age of 25, while the greatest number develop between the ages of 30 and 40 years. The unmarried state predisposes women to the development of uterine fibroids. Married women who prevent conception, while less liable to develop fibroids than unmarried women, are still much more prone to them than childbearing women. Childbear- ing women are the least predisposed to fibroid of the uterus. Xegro women are predisposed to uterine fibroids. LECTURE II. Symptoms — Diagnosis. A knowledge of the existence of a fibroid tumor of the uterus may be gained by the diagnostician by first (obtaining the symptoms as appreciated by the patient — the subjective symptoms; and further by acquainting himself with the actual physical changes by direct personal examination of the patient — the objective symptoms. SUBJECTIVE SYMPTOMS. Pelvic Symptoms. — Among the early local symp- toms of fibroid tumors of the uterus may be enumer- ated an irritable bladder amounting frequently to positive dysurea; rectal pressure; sensation of pelvic fullness; low backache or sacralgia, and frequently pain on cohabitation. These symptoms are all ijro- duced by a gradually enlarging uterus, and resemble many of the pelvic disturbances of early pregnancy, from which they must be differentiated. As the tumor enlarges ihe sensation of fullness extends to the lower abdomen, the j^ressure on the nerves to the lower extremities causes pain in the line of the nerves on the anterior or posterior aspect of the thigh, or on both. Even edema of the extremities may occur from pressure on the veins extending to them, and the appendages are frequently pressed upon, resulting in severe pain on one or both sides, while as the tumor begins to fill the abdomen symptoms of painful pressure on many or all the imp(H'tant organs of the pelvis will be experienced. 18 Symptoms due to Functional Disturbances. — The most important symptom under this head is that due to the disturbance of the function of menstruation. In 75 per cent, of all fibroid tumors of the uterus the menstrual flow is increased, on account, 1, of increased area of the endometrium due to interstitial enlarge- ment of the uterus, 2, of increased vascularity of the uterus due to the demands of the hypertrophied tis- sues, and 3, to the venous blood congestion due to pelvic i^ressure. In a large majority of cases pain is an accompanying symptom. This dysmenorrhea is caused, either by the abnormal contractile power of the changed uterus, by submucous projections into the uterine cavity, exciting painful contractions of the organ, or by a frequently accompanying endometritis. The development of the tumor influences decidedly the change of the menstrual function. In the early stages of the fibroid the patient will notice but a slight lengthening of the menstruation, but as further devel- opment is made the quantity of the flow will be in- creased. This changed condition, while at first it may attract the attention very slightly, as it gradually in- creases, will at last convince the patient that some- thing serious is afflicting her. The flow will increase rapidly, not only in length of period, and in quantity at a given time, but finally it will frequently become irregular and occasionally almost continuous. At the same time pain will often gradually develop, so that with the exhaustion of depletion will come the agony of physical suft'ering. These pains if caused by en- dometritis, will be of a dull aching character, accom- panied occasionally with slight uterine contractions; if caused by the effort of the uterus to expel submu- cous masses or polypi, it will be like those accompa- nying the uterine expulsive pains of a miscarriage or confinement; if caused ])y a pressure of the inordin- ately congested hypertrophied uterus upon the tubes and ovaries it will be severe and of an almost continu- ous character in the ovarian regions. The function of the bladder suffers from direct 19 pressure of the enlarged uterus, or from a subperito- neal enlargement. Frequent urination will first be noticeable, while the tumor is yet small, and later pain- ful micturition, with severe lasting x^ain in the bladder, as a direct result of traumatism produced by the en- croachments of the uterus. Comjilete stopi)age of the urine and painful distention of the bladder may finally occur from impaction of the increasing tumor. The function of the rectum is frequently im^^aired by direct pressure of the tumor uj^on that organ. Obstinate constipation will be complained of, while the interference of the tumor with the circulation will favor the development of hemorrhoids and their pain- ful symptoms. Temporary imi3action of feces in the large and small intestines occur as a direct result of the pressure of a large tumor. Deformity Produced by Fibroids. — One of the most embarrassing symjDtoms to many patients, who are afflicted with fibroid tumors, and frequently the firsi to attract their attention, is the change in the contour of the abdomen, which is enlarging. Upon closer ob- servation and examination of the lower abdomen, they discover the un wieldly mass, the tumor, which, as it gradually increases in size, produces a deformity that no device can conceal, while the patient, in order to maintain an upright position, must throw her shoul- ders back in a manner to make the tumor appear most embarrassingly conspicuous. General Co)istifufiona1 Disturbances. — Reflex ner- vous disturbances are early symptoms in many of these cases. Nausea, palpitation of the heart, indi- gestion, gaseous distensions of the bowels, flashes of heat due to vasomotor disturbances, headache, dizzi- ness, occasionally spasmodic cough and all the symj)- toms accomj^anying nervous storms, irritable temper, , from dynamos of the non -alternating or non-interrupting variety employed for incandescent street or house lighting and c, stor- age or secondary batteries, PRIMARY BATTERY. There are several distinct fcjrms of primary cells emijloyed by gynecolcjgists in the treatment of fibroids: Portahh Battery. — The old reliable pm-table bat- tery is the one with zinc and carbon elements excited 47 by a fluid of sulphuric acid and bichromate of potas- slum in water in cells of glass, or better, hard rubber. The voltage of each of these cells when freshly charged is about 2 volts. Therefore a battery of this descrip- tion of about 18 cells properly connected makes a very suitable portable battery for the treatment of fibroids. There are several so-called dry-cell batteries of secret construction which appeal to one on superficial observation, because of the claims of their inventors, of cleanliness, durability, and freedom from objec- tionable fluids. All such batteries should be looked upon with suspicion, until they have proved them- selves capable of furnishing an electro-motive force of from 30 to 40 volts for periods of five to ten minutes, several times a day for several months, otherwise the cost of recharging makes them too exiDensive. Office Batteries. — For office battery where porta- bility is not required, the Law cell, the improved Le Clanche, the Diamond Carbon, or cells of similar con- struction should be employed. They should be attached to a selective switchboard of such a construc- tion that any portion of the battery may be employed at will. These cells may be placed in an adjoining closet, or cellar, and connected with the switchboard by a cable of wire, or they may be placed in a cabinet beneath the switchboard. As these cells have an average voltage of one or one and a quarter volts each, a battery of about 40 cells should be selected. Streei Wire Current. — One of the most satisfactory office fixtures for electricity is a connection from an incandescent lighting system of the uninterrupted or non-alternating variety reduced by some safe form of rheostat. One of the simplest rheostats is the Mc- intosh (Fig. 1). It is comi:)act, easily comi^rehended and regulates the current in gradations from zero to the full strength of the street current, and reverse, without the slightest possibility of a break. A fuse box is also connected with this rheostat which will bum out and disconnect the current from the patient 48 in case of an accidental dangerous increase of the elec- tricity from any nnlooked for source. Storage Ixitttn'ies may be used as a source of elec- tricity for gynecologic practice. However, as they are not econ(jniical and wherever they can be used to advantage they must be near some other source of elec- 49 tricity, it is obvious that one would seldom select this form of battery. MILLIAMPERE METER. To employ galvanism in gynecologic practice with- out a milliampere meter is criminal. There are three reasons for this: 1, because the resistance through the abdominal walls is so small and variable, that no one, no matter how experienced, can even approximately estimate the amperage of a current by the number of cells employed. 2, because of the powerful current often required in this kind of work, a dangerous dose might easily be given, and 3, because of inaccuracy in recording cases. F Kit- RE -2. A milliampere meter should be selected which has two readings : One scale reading to 500 milliamperes and one reading to 50 milliamperes. This presup- poses in reality a double instrument. By changing a switch either reading may be selected without the necessity of changing the connections. The best milliampere meter I am acquainted with is the Weston. It is reliable, convenient, double reading, dead beat, and can be used in any position on a level without regard to the poles of the earth. The principal objection to this instrument for general use is its expense (Fig. 2). 50 An instrument which I have employed more than any other in my work outside of the office is the Mc- intosh instrument (Fig.3). It is of the galvanometer type and much cheaper than the Weston. It is ap- proximately correct, and bamng the fact that it must be carefully adjusted to the polarity of the earth, be- fore each using, and that the indicator is not dead beat, it is a very satisfactory instrument. It has a double reading; is made in two sizes, one large for office use and one small for portable purposes. ELECTRODES. In describing electrodes for use in the treatment of Figukp: s. fibroid tumors I will limit my description to those which I actually employ in my own work and leave the innumerable confusing curiosities which adorn the ordinary instrument catalogues unmentioned. Ahdominal electrodes in use by me are of two kinds according to the dose required. When a current of less than 50 milliamperes is employed a large si^onge, a large felt (^r a large spongio-pyoline instrument may be emjjloyed. These electrodes should be not less than six })y eight inches of an oval shape. They shoukl be thoroughly washed in warm water before using, and all surplus water squeezed out before the 51 application is made. For a current above 50 milliam- peres a clay electrode or the author's membranous abdominal electrode should be emx)loyed. These being the only instruments which I have found in my experience which will uniformly distribute the cuiTent and prevent burning of the skin in spots. The clay electrode is the cheapest form of the two. If made as recommended by Goelet, wrapped in cheese cloth with a rubber back it is comparatively clean and makes a suitable instrument where efficiency and economy alone is desirable. It is constructed of jjot- ter's clay of the consistency of putty molded into a cake, about eight by six inches in diameter by one inch in thickness. Fiia-RE 4. The membranous abdominal electrode devised by the writer, is a water electrode, the cavity of the disk hold- ing the water being covered with animal membrane, the membrane furnishing the surface of contact (Fig, 4). This instrument when filled with warm water makes an ideal electrode. It is cleanly, its temperature is easily regulated and it diffuses the current perfectly. For internal electrodes I employ intrauterine, vagi- nal and rectal instruments. The intrauterine electrodes are of two varieties; flexible concentration and soft copper. The flexible concentration consists of platinum wire wound spirally over soft copper for varying distances tipped with hard rubber, and the portion of the in- 52 strument not active, is covered with some insulating material as rubber or linen covered with shellac. These instruments may be made of any diameter. I have them in sets of two, three and five millimeters in diameter respectively. The active surface which I ordinarily employ is four square centimeters (Fig. 5). In knowing accurately the active surface of an elec- trode, one can estimate more definitely the particular effect to be exj^ected from a known current. This will be explained more comprehensively when we con- sider treatment technique. Soft copi:)er electrodes are employed in order that the uterine mucous membrane and deeper tissues may become infiltrated by cataphoresis with the salts of copper produced by a combination of tissue and cop- o^ Figure 6. per electrolysis, which occurs at the positive j^ole. I have these electrodes made in sets of three instru- ments, each instrument having an electrode of diifer- ent caliber on either end (Fig. 6). This makes six diameters — 2, 4, 6, 8, 10 and 12 millimeters. The length of each electrode surface is six inches. The portion of the staff not employed in the uterine canal is insulated with a loose rubber muff. Vfujinal electrode. — I employ an instrument for this purpose like the one shown in Fig. 7. It has an active surface of alxjut sixteen square centimeters, the staff of it being insulated with hard rubber over a copper core. The instrument is about six inches long and about three-quarters (jf an inch in diameter. ReeUd electrode. — I employ a long bulbous- pointed instrument about four inches long and one- 53 half inch in diameter for a rectal electrode. The insu- lated portion has a metal surface of about ten square centimeters. The staff is insulated with hard rubber. Effects of Galvanism on Living Tissues. — Fortu- nately the effects of electricity upon living tissues has been so thoroughly studied, clinically and experi- mentally, in the last few years that we are in a posi- tion to make some i^retty definite statements about its action. These studies, too, have not been limited to the living tissues, but have been carried into the chemic, physiologic and bacteriologic laboratories to such an extent that we have many experimental proofs which have proved true several former theories and exploded many others. In applying galvanism to the tissues of the body the employment of two electrodes is necessary. In applying electricity to fibroids of the uterus the inter- nal electrode is usually termed the active pole while the external one is called the passive pole. We speak, therefore, of three kinds of effects from the applica- tion of the current in this manner: Polar effects, inter-polar effects and general effects. The polar effects differ materially with the pole employed. In several respects the effects at the two poles are diametrically opposed. Effect on Sensihility. -The positive pole or anode acts as a sedative while the negative or cathode pole acts as an irritant. This effect on the sensory nerves is called the electro-tonic effect and the two effects are ex- pressed as the anelectro-tonic effect ( sedative ) and the catelectro-tonic effect (irritant). The use of electricity in gynecology with its employment of large doses has abundantly demonstrated to me the electro-tonic effect of galvanism. Effect on Blood Vessels. — The i^ositive pole con- tracts blood vessels in its immediate neighborhood while the negative pole dilates them. These vaso-con- strictor and vaso-dilator effects are easily demon- strated. Chemic Reaction. — The result of tissue electrolysis 54 between the poles produces an accumulation of alkalin elements at the negative pole and acid elements at the positive pole. This results in an acid reaction ob- taining at the positive pole and an alkalin reaction at the negative pole. If the electrolysis is persisted in with a powerful dose these polar accumulations become caustic acids and caustic alkalies resiDectively. Effect on Tissue. — The acid accumulation at the positive pole when it becomes sufficiently concen- trated fi'om the effect of a strong dose coagulates the soft tissues and renders them for a short distance from the i3ole hard and dry. On the other hand the alkalin accumulation at the negative pole when strongly con- centrated by a strong dose of electricity, dissolves the tissues and liquifies in the same manner as does caustic alkalies. Effect on Pathogenic Microbes. — A zone of uterine tissue around the positive pole of a depth varying from a fraction of a millimeter to one or two millime- ters according to whether the dose of current is small or great is rendered bacteriologically sterile by the employment of the galvanic current. This effect according to experiments made by Gautier, Apostoli, Enrico Burci, Vittorio Frascani and others, is not due to the electricity direct but rather to the chemic changes occurring around the positive pole as the result of electrolysis. For instance, if a copper elec- trode is employed oxychlorid of copper is formed as the result of a combination between the electrolyzed tissues and copper. This chemic combination is an active germ destroyer and in solution it is driven by cataphoresis into the tissues to a considerable distance, carrying its antiseptic projjerties with it. There is scarcely any antiseptic effect at the negative pole. INTERPOLAR EFFECTS. While it is easy to demonstrate polar action it is not an easy matter to make an ocular demonstration of the interpolar effects of the galvanic current on living tissues. 00 From exj)erience in the emi^loyment of this current on living healthy and ]3athologic tissue, experience of many earnest investigators extending over a period now of several years, we are convinced that evidence enough has accumulated to justify us in saying that the following definite effects occur in tissues so acted upon: 1, interpolar electrolysis, 2, stimulation of trophic nerves, 8, cataphoric action. Interpolar Electrolijsis undoubtedty occurs be- tween the poles as well as at the metal poles them- selves. When such electrolysis occurs in a fibrcjid uterus it is easy to account for the reduction in size of that growth. When the molecules of weaker ten- acity in such tissues become decomposed into their constituent elements ozygen, hydrogen, carbon, etc., these elements, as gas or solid i^articles, immediately on their release become foreign substances. While seeking for new combinations some of them are taken into some of the many absorbents traversing the tis- sues and are carried out of the system. Others form new combinations with free elements in the tissues, or with the decomposed material of the electrodes, or fluids surrounding the electrodes on the surface, and still others are liberated at the poles as solids or gases. Stimulation of Trophic Nerves. — While the elec- trolytic effect of the current may account for reduc- tion or absorption of growths, I believe that this re- sult is materially hastened by powerful stimulation of the trophic apparatus of the uterus by electricity. We are forced to believe this by the fact that the general nutrition and functional activity of all the organs, any way coming under the influence of the current, are markedly improved. The Cataphoric Action of the Galvanic Current. — This is the property of a current of electricity which enables it to push or conduct fluids in bulk through membranous or porous conductors in the direction of the current flow, from the positive toward the nega- tive pole. This is also called electrical cataphoresis. Fluids near or on the positive pole, either simple or 56 holding in solution drugs or chemicals, will be driven into the living tissues when living tissues are made a portion of the conductor. So that the tissues of the uterus may become impregnated with any drug which can be dissolved in water by sun-ounding an intra- uterine iDOsitive electrode with a film of cotton satu- rated with the particular fluid and causing a current to traverse the tissues. TJie general effect of galvanism upon the tissues is that of a powerful tonic. Irregular practitioners, for a large number of years, employed electricity in some form successfully because of its power to stimulate general nutrition. It mattered but little what form of electricity was employed, or where it was applied so long as some portion of the sick man became a part of an electric circuit; it was sure to stimulate him, im- prove his nutrition and make him feel a stronger man. The powerful doses employed in the use of gal- vanism in the treatment of fibroids exaggerates this tonic effect of electricity to such a degree that many physicians have endeavored to attribute to it all the credit for improvement of fibroids under electricity. Summary of Effects of Galvanism in the Treat- ment of Fibroids of the Uterus. Polar Action: Negative Pole a. Irritant; h. Vaso- dilator; c. Alkalin; d. Liquifies tissues; e. Anti- septic (slight). Positive Pole a. Sedative; b. Vaso-constrictor; c. Acid; d. Coagulates tissues; e. Antiseptic (powerful). Interpolar action: Electrolysis and trophic stimu- lation. General Action: Powerful tonic. THE APPLICATION OF GALVANISM TO THE TREATMENT OF FIBROIDS. What is the present status of the treatment of these benign tumors by electricity? With the brilliant results of i)resent surgery as a competitor, one must have considerable courage to offer electricity as a remedy at all in these cases. But as an abdominal 57 surgeon with at least average success, and at the same time as one who interested himself early and enthusi- astically in the much-lauded Ajiostoli treatment when it made its (Uhutin this country, I am constrained by sense of justice, knowing well both sides, to say that in the interest of those who have fibroids of the uterus, that the knife, even in these times of brilliant successes in surgery, is used too often and electricity too little. If a brilliant hysterectomy with its aver- age mortality of 5 per cent, ended the matter, and the 95 per cent, recovering gained health immediately, we could have but little to say. When, however, we must reckon on the months of nervous suffering with which the majority of these patients who have their tumors removed have to contend, after this operation, before they receive the well-earned cure, and when we take into consideration the not large but certain per- centage of fistulas, hernias and other well-known dis- tressing sequelae following oiDerations, and last but not least when we remember the grim specter of that 5 or 10 per cent, who did not recover, are we not justified if we have a conscience (especially when we realize that a fibroid of the uterus when left alone seldom proves fatal) in giving our patients the benefit of a treat- ment, which seldom fails to relieve these cases, and while it frequently fails to cure, never kills and never does harm and never inferferes ivifh the success of an operation, if it in the end fails to cure? Experience in the treatment of fibroids of the uterus by electricity has taught me how to select my cases, when to encourage a patient to receive elec- tricity and when to encourage her to select an opera- tion. Rules which I have formulated and allowed to influence me but not control me (because I make frequent exceptions to them in individual cases) are as follows: WHEN ELECTRICITY IS SPECIALLY INDICATED. 1. In bleeding fibroids in women approaching the menox^ause. 58 2. In all inoperable cases. 3. In incipient fibroids in women over 40 years of age. 4. In all bleeding fibroids of the smooth interstitial variety which have no symptoms but hemorrhage. 5. In all cases (not accompanied with pelvic pus accumulation) which refuse to have an operation. TECHNIQUE OF TREATMENT OF TYPICAL CASES. A typical case for the successful treatment of fibroids of the uterus by electricity is that of the inter- stitial variety, in which the new tissue is uniformly distributed throughout the uterus, enlarging it to a symmetrical tumor of varying sizes, and proportion- ately expanding the uterine canal. These cases are almost invariably of the hemorrhagic variety because of the expansion of the uterine mucous membrane. The hemorrhage occurs as an exaggerated menstrual flow. These tumors vary in size from a growth the size of one's fist to a tumor filling the abdomen with a uterine canal many inches deep. Those not exceed- ing six to eight inches in length and three to four inches in lateral diameter are the ones in which elec- tricity accomplishes the best results. METHOD OF PROCEDURE. We seek in these cases, a, to transmit through these tumors, for its electrolytic effect, as strong a current of galvanism as the patient will bear, without severe discomfort, and, at the same time, not to severely cauterize the tissue at the poles, b, We seek to get acid accumulation at the positive pole located in the uterus, of sufficient density to coagulate the tissues and thus lessen the bleeding c, This same acid at the positive pole we expect to combine with the cojji^er of the electrode and form salts, which salts in solution, by the cataphoric action of the current will be driven into the uterine tissues, immediately surrounding the electrode, and as a styptic materially aid in curing excessive flow, d, We seek further to 59 obtain the powerful antiseptic effect as the result of chemic changes occurring around the internal elec- trode, in order to cure the endometritis which almost invariably exists as a painful accompaniment of fibroids. After an antiseptic vaginal douche the patient to be treated is placed upon a table on her back with her buttocks drawn well to the edge and feet supxDorted by stirrups. The size, shape and direction of the uterine canal is obtained by the use of large, flexible sounds. A large copper electrode, then, of suitable diameter, is properly shaped and passed to the bottom of the uterine canal, and the vaginal portion insulated with the'rubber muff. This electrode is then attached to the positive terminal of the battery. A clay, or the writer's membranous abdominal electrode, is next passed under the loose clothing and placed on the abdomen and then attached to the negative pole of the battery. The current is now gradually turned on while the milliampere meter is carefully watched and the fea- tures of the patient are closely scanned for signs of pain, until the current reaches 100 to 150 or even 200 milliamiDeres, according to the tolerance of the patient and the size of the active internal electrode. If the active electrode is of the ordinary diameter of from 3 to 5 millimeters, a current strength of 100 milliamperes can be used safely in any particular case for every two inches in length of this electrode which is active. To he more accurate, the current should not exceed in strength 25 milliamperes for each square centimeter of active surface of the internal electrode. So that in the general run of cases one can safely give the patient as strong a current as she will bear without danger of producing excessive cauterization at the active pole. This will vary from 100 to 200 milliamperes. The time of each treatment should be five minutes for the maximum current employed. The treatment should be given as often as every sec- ond day. Except in cases of continuous flowing, the 60 treatments are best given between the menstrual periods. These cases begin to improve almost immediately. The lirst improvement is in relief of neuralgic and so-called pressure pain. In a few days they find that their general strength is improved. Reflex disturb- ances such as stomach irritation, palpitation of the heart, occipital headache and backache will be re- lieved. The patient will begin to eat and sleep nat- urally. There is a general feeling of well being engendered. In a few days the leucorrhea or puru- ent discharge from the endometrium will diminish. As the patient arrives near the menstrual period, she finds that the old premenstrual aches are not present, the old despondency is absent. If the treatment has been sufficiently active the menstrual flow will arrive without iDain frequently. Occasionally, the first month, the flowing is fully as free as usual, although frequently it is much less. If the treatment is con- tinued for two or three months these patients will begin to maintain that they feel perfectly well. All the old distressing symptoms will very often dis- appear entirely, they will gain flesh and the uterine discharge will become normal. While the tumor will still be apparent to the physician's examination it will almost invariably be found to be much dimin- ished in size. When the time arrives in the treatment that these patients are symx^tomatically cured, that is when they feel no symiotoms, I usually discharge them. I always inform them that the tumor has not disappeared, and that sometime it may again give them the old difficulties. As long as they are free from these they may be satisfied that the tumor is not growing — on the contrary decreasing in size. However, if the old symj)toms begin to return I instruct them to seek relief again in the electricity. The above treatment applies to the typical bleeding fibroids of interstitial variety. Where the uterus is large and the canal is deep, it is necessary sometimes to attack the mucous mem- 61 brane by piecemeal, in order to get sufficient concen- tration with the dose tolerated to accomplish sufficient changes in "the endometrium to check hemorrhage. The concentration necessary should approximate 25 milliamperes for each square centimeter of the elec- trode in contact with the mucous membrane. For examiDle, if a patient will only bear a current of 100 milliamxDeres, one should select an electrode of copper or zinc or platinum with a diameter of proper dimen- sions, insulated to all but 4 square centimeters of its distal end. The depth of the canal is measured. Then commencing with the distal end of the cavity, the exposed active surface of the electrode is made to cover in successive treatments its whole surface. By doing this the whole mucous membrane is acted uj^on uniforndy without employing at any time a larger dose than 100 milliamperes. INOPERABLE AND COMPLICATED CASES. The cases which are referred to the writer for elec- trical treatment, in these days when active surgery offers such a large percentage of recoveries from hys- terectomies^ are for the most part complicated cases, which the ordinary surgeon shuns. One complication which frequently induces the sur- geon to shift the responsibility of these cases, is that of severe purulent metritis and endometritis, accom- I^anied frequently with discharges of gangrenous masses from submucous fibroids, all accompanied with much pain, more or less hemorrhage, and with the discharges inclined to be very offensive. The patients are usually poorly nourished, with white and waxy skin in consequence of septic absorptions. When they reach this stage they are frequently pronounced malignant. The outlook for an operation certainly is not flattering. Now the writer has been honored frequently by having such cases sent to him for electrical treatment, by different friends of his who are conscientious sur- geons. 62 What have we to deal with? Usually a tumor of large size extending to the navel. It is soft, with nodular masses projecting from its peritoneal surfaces. The cervix is soft and patulous, with a canal large and irregular. Sometimes a small nodular mass is pre- senting at the cervix, This is usually soft and easily broken down. The endometrium and all cavities from which masses have been projected or from which masses have sloughed away are infected and ulcerat- ing, and emitting a discharge which rapidly becomes offensive. From the large mucous membrane periodic and irregular uterine discharges are occurring, serving to swell the already copious outpour. The writer has treated by electricity and symptom- atically cured several of these cases in which a diag- nosis of cancer had been made by men of more than ordinary talent. I prefer, when it is practicable, to dilate the canals carefully in these cases, and remove with a dull curette the sui3erficial debris before beginning the electricity. I then select one of the largest copper electrodes which can be inserted and make it the active positive pole, inserting it to the bottom of the canal with its whole surface uninsulated.' With the abdominal elec- trode in place, a current is gradually turned on until a strength of 200 milliamperes is reached, or the max- imum amount under that strength that the patient will tolerate. These treatments should be given every other day. Antiseptic douches should be employed night and morning. These cases respond rapidly. The powerful anti- seijtic action on the mucous membrane makes itself apparent by the decreased odor of the discharge. The passing and withdrawing of the electrode opens and provides free drainage for the secretions. The tissues become tanned by the salts of copper which are forced into them by catai)horesis, and the discharge of blood is lessened. The patient is toned by the general efPect of electricity on her system. In a word, it is fre- 63 quently marvelous what a transformation will take place in these apjmrently hopeless cases in a few weeks of judicious galvanic treatment. While these cases are apparently hopeless, often- times when they are "given over' by the surgeon, they are frequently symi)tomatically cured by this simple remedy. The writer has a long list of such cases, and they constitute some of the most satisfac- tory work he has ever had placed to his credit. INOPERABLE TUMORS TREATED BY OTHER THAN THE INTRAUTERINE METHOD. There is a class of comi^licated cases of difiPerent kinds in which it is impossible, because of the contor- tions of the growth, to enter the uterine canal with an electrode. Occasionally the tumor has displaced the cervix so that it is drawn high in the vagina above the bladder, out of reach of finger or sound; while again it is drawn up posteriorly with the uterine canal forming an acute angle with the vagina. In all cases where it is imjoossible to reach the canal, if they are treated by electricity, it is necessary to employ it without the advantages of an intrauterine electrode. Only in the most desperate cases, in which submit- ting to an operation is clearly suicidal, would one think of employing electricity as a means of treat- ment, when an intrauterine electrode was impossible. But it is in just these cases, with their distressing neuralgic and pressure symptoms, with dyspeptic com- plainings and bowel irritations, the result of reflex nerve disturbances, in which an operation is discour- aged, that we find patients ready to catch at any straw. In many of these cases I believe that electricity not only offers a straw, but a veritable lifeboat to their despairing bodies. When an intrauterine electrode is not practicable, then we should employ some other form of internal electrode which will have the effect of causing the current of galvanism to pass directly through the largest portion of the tumor. 64 If the vagina is not distorted so but that a vaginal electrode may be employed, that instrument should be used (Fig. 7), placing its active point posterior to the tumor. This should be made tiie negative pole. The abdominal electrode should be placed in such a position that the largest diameter of the tumor is interposed between it aiid the vaginal electrode. A current of 50 to 100 milliamjjeres may be safely em- ployed, if tolerated, for a period of five minutes. The treatments may be given as often as every second day, and in a few cases every day where it is well borne. When a vaginal electrode can not be employed to advantage in these cases, a rectal electrode (Fig. 8) should be employed. This should be placed well up opposite the tumor. It should be employed as the Figure 7. Figure 8. negative pole. It should have an active surface of more than eight centimeters and the current should never exceed 200 milliamperes. All we can expect to accomplish in this treatment is that beneficial action derived from passing a strong direct current through any tissue containing muscles, nerves, lymphatics and blood vessels, viz., a powerful trophic stimulation to the part, and incidentally a powerful general tonic effect on the general system. These cases get great relief. Neuralgias stop. Troublesome abdominal reflexes cease. Circulation is improved. Nutrition is stimulated. Sleei)lessness disappears. Bowels are stimulated and relieved of troublesome distension symptoms. The tumors often seem to decrease in size. The degree to which each 65 of these symptoms are relieved varies, of course, much in individual cases. The writer has seen a large num- ber of cases completely and for an indefinite time, relieved of all these symptoms. In fact, some of the most gratifying cases of relief he has, are of this variety„ Their cases are apparently so hopeless that often any relief is very gratifying. LECTUKE VI. SURGICAL environments: operating room; steril- izers; STERILIZING INSTRUMENTS, LIGATURES AND hands; CATGUT PREPARATIONS; PREPARATORY AND AFTER TREATMENT OP PATIENTS. DRAINAGE. The environments of a patient who is about to submit to a surgical oiDeration for a fibroid of the uterus must be made surgically clean.. These environments include operating room, bed, sterilizers, instruments, ligatures and operators' and assistants' hands and clothing. OPERATING ROOM. In a imvate house a room should be selected which has direct light through one or two large windows; a room which can be stripped of furniture, hangings and carpets. It should be convenient to the bedroom of the patient, or better the bed can be placed in the room in readiness for use when the o^oeration is fin- ished — the operating room constituting the bedroom. The woodwork of this room should be thoroughly scrubbed with soap and water, and the walls and ceil- ing carefully wiped free of dust. The room should be thoroughly aired by opening the windows and a reliable means of heating should be at hand in order to render it dry and to keep it at a temperature of 80 degrees F. when required. The table, which is selected for the operating table, and the stands for instruments and dressings, together with all recep- tacles or slop tubs and basins should be carefully scrublx^d and then conscientiously wiped with a 1:500 solution of chlorid of mc^rcury. All tin, iron or i3orce. lain basins should be boilM for one-half hour in a wash 67 boiler or other large boiler, as a means of sterilization Tho bed, if possible, should consist of a hair mat- tress which has recently been purified by steam. In a hospital a largo steam sterilizer should be jirovided where hair mattresses can be sterilized frequently. The bed should be comjjleted with dry sterilized sheets, blankets and pillow slips. If there is no sterilizer at hand the bedding can be sterilized by boiling in water one-half hour, and drying in a pure room, and ironing with a hot iron by an intelligent attendant or nurse. Growns, towels and aprons should be sterilized in the same manner as the bedding, pro- vided there is no regular steam sterilizer at hand. In an institution the operating room should have floor and walls of such material that they can be thor- oughly washed with antiseptic solutions and jjrovided with a central drain which will allow the cleaning of the walls and floors with water direct from a hydrant through a hose. The drain should be reliably trapped, or better, drain directly in to the external air. For convenience, a perfectly fitted oj^erating room should have several anterooms, including a preparatory room where the solutions are prepared, the water sterilized, and where the heating apparatus for the sterilizers and the sterilizers themselves are located. This room should have washable walls. There should also be one or more anesthetizing rooms, and finally there should be convenient dressing and wash rooms for the surgeon and his assistants. The private operating room which I use at the Woman's Hospital is shown in Fig. 9. It has direct side light and a large skylight. Its walls and floors are of marble. It is lighted at night entirely by incandescent electric lights, gas being impracticable where an anesthetic is necessary; these lights are in abundance, so that an operation can be performed equally well at night or day. The prepar- atory room is adjacent. This is shown in Fig. 10. It is entirely in marble. The battery of Boeckmann's sterilizers is shown in the foreground. In the far- ther end are two large tanks in which the water is 68 sterilized for the operation, one being filled with cold sterilized Avater and the other with hot water. They are connected with the operating room by large fau- cets which pass through the wall. Directly otf from this room is an anesthetizing room, and adjacent to this are two dressing rooms with washing utensils. In the oj)erating room is a spectators' rail which sep- arates the ojDerator, assistants, nurses and all operat- ing paraphernalia from those who may be invited to vritness operations. Sterilizers. — In a private house, in emergency cases, an ordinary copper or tin wash boiler may take the place of the most elaborate sterilizer. The gowns, towels, gauze operating sheets and all large articles used externally can be thoroughly sterilized by boil- ing for thirty minutes. For sterilizing instruments, silkworm gut, silk and other smaller articles a smaller kitchen article such as a sauce pan, or porcelain- lined flat pan, may be utilized as a sterilizer. In large institutions large steam sterilizers are em- ployed. I have used the Arnold sterilizer for dress- ings and instruments and other small articles until quite recently, since which time I have adopted for my hospital work the Boeckmann steam sterilizer (Fig. 11). These sterilizers are simple in construction, dur- able, inexpensive, efficient for all work, even the steril- ization of catgut, and they possess the advantage of sterilizing with steam, while at the same time when the process is finished the articles are left perfectly dry. At the Woman's Hospital several of these sterilizers are employed and everything that is liable to be required in several operations is sterilized, and the unopened sterilizers are placed in the operating room for future use. Surgeon's and nurses' gowns, towels, gauze, silk and silkworm gut in cotton -stoppered test tuVjes are removed as they are required at the time oi the operation, while a separate hot water sterilizer (Fig. 12) is employed immediately before the opera- tion for steriliziug iho instruments. Lif/atures.—l employ braided silk, silkworm gut 71 and catgut for sutures and ligatures. Silk and silk> worm gut I sterilize by boiling, or by steam in the Boeckmann sterilizer. They are placed in small skeins in large test tubes loosely stoppered with cotton and subjected to a temperature of boiling water for twenty minutes on two successive days when t have no sterilizer at hand, and to the temperature of the superheated steam for a like length of time in my hospital work. I only open at the operation a sufficient number of tubes ^^ Figure 11. for the operation in hand, the balance being reserved for future cases. Tubes of silk and silkworm gut may be prepared in considerable numbers and sterilized by steam with an efficient cotton filter and afterward car- ried to operations anywhere. On opening, the cotton stopper is first burned down low with the tube, then removed and the skein of material carefully lifted out 72 with sterilized forceps and placed in sterilized water when it is ready for use. Cat gut is the form of absorbable ligature which I, employ for buried sutures. I have it sterilized in the Boeckmann sterilizer with dry heat at a temperature of 284 degrees F. for a period of three hours. Previ- ous to sterilization, the catgut, cut in suitable lengths, is wrapped in oiled paper, one thread in each paper and the paper enclosed in small hermetically sealed envelopes. While this accomplishes perfect steriliza- tion, as can be demonstrated by bacteriologic tests it has been argued that sterilized catgut may act as a very favorable nidus for the growth of pathogenic germs in tissues in which it is buried, tissues which Figure 12.— Boeckmann*s Instrument Sterilizer. without the presence of this i)erfect sterilized culture medium would be competent to resist the few germs left in a wound, after ordinary surgical precautions had been exerted. For this reason I not only render my catgut aseptic with heat but I sui)plement that process by saturating it with non-poisrmous antisep- tics. According to Arthur Wocxlward Booth's admir- able article in the TJirrdpculir (Jfrzcffr, December, 1894, he found that pyoctanin blue in a 1 to 1000 alcoholic solution will render catgut thoroughly anti- septic and at the same time imjjart to it a longer life. Pyoct?inin is a much more i)owerful antise])tic than chromic acid and therefore may be employed in more 73 diluted form. Compared with bichlorid of mercury it is a more perfect germicide, non-poisonous, and it im- parts a longer life to the gut. Catgut saturated with pyoktanin becomes an antiseptic suture, the antiseptic of which can in no way prove a source of danger. THE writer's method OF CATGUT PREPARATIONS. A skein of new catgut is cut into about four lengths. This makes the threads of about forty inches each. Each section of the skein is twisted into a loose knot and they are soaked in ether for twenty-four hours in order to remove the fat. It is then boiled in alcohol, in a closed jar, for one hour in the steam sterilizer. Before boiling in alcohol the bunches are divided into their separate threads and each thread twisted into a little coil. After the sterilization by alcohol it is care- fully removed from the jar by an intelligent conscien- tious nurse, with sterilized forceps in sterilized hands, to a jar containing a solution of pyoctanin 1 to 1000 in absolute alcohol. Here it is allowed to remain for twenty-four hours in order to become thoroughly sat- urated with that powerful antiseptic. I then have it distributed into small wide-mouthed one-half ounce bottles, containing oil of juniper. Into each of these bottles about four of the forty-inch strands are placed. The bottle is then corked with a rubber stopi^er and is not opened until it is to be used at an operation, when the catgut is threaded directly from the bottle. The bottle, or several bottles, with their rubbsr stop- pers may be immersed in a 1 to 1000 bichlorid solution on the instrument table ready to be opened by the sur- gical nurse in the course of the operation. After it has once been opened I discard any small amount of catgut which may remain after the operation, prefer- ring to use always from a fresh supply. Instead of boiling the catgut in alcohol it may be sterilized in closed enveloi^es in the Boeckmann ster- ilizer as before described, at a temperature of 284 degrees F., and then treated from that point in the same way as that sterilized by boiling in alcohol. 74 It seems to me that this is an ideal and simple method of catgut preparation. There can be no doubt of its absolute sterilization after it has been boiled in alcohol for two hours, or after it has been submitted for three hours to a temperature of 284 degrees F. in the sealed enveloi^es in the Boeckmann sterilizer. Dr. Booth found that pyoktanin permeated every fiber of catgut when it had lain in a 1 to 1000 alcoholic solution of the drug for twenty-four hours. Dr. Booth quotes Sternberg as quoting Jaenicke on the antiseptic properties of pyoctanin as follows: Staphylococcus pyogenes aureus restrained by solu- tion of 1 to 2,000,000; bacillus anthrax aureus re- strained by solution of 1 to 1,000,000; streptococcus pyogenes aureus restrained by solution of 1 to 333,000. In blood serum stronger solutions are required. Thus we have not only a sterile catgut, but we have that sterile catgut thoroughly saturated with an effi- cient and non-poisonous antiseptic. The juniper oil preserves the catgut indefinitely, it fixes the pyctanin so that it will not stain the hands, and it keeps the catgut soft and pliable. The life of the catgut in the tissues prepared by this method is a little less than that prepared by chromic acid, but considerably longer than that prepared by bichlorid of mercury. By placing it in small bottles it can be handled economically without the necessity of ever being obliged to open twice the same supply. Spomjes. — Sea sponges are not safe when prepared under the most careful supervision, whereas gauze sponges may be perfectly reliable whenever there is the simplest device at hand in which they may be boiled. The best gauze sponges are made from loose-mesh gauze folded into three or four thicknesses, with the edges fastened with a running stitch of cotton thread. They may be made of any size. These sponges are sterilized in a steam sterilizer, or in emergency cases they may be sterilized by })oiling with the instruments. In laparotomy cases I prefer those sterilized by the 76 dry metliod. They are then used but orice and are discarded. This is not economical because of the large number of sponges frequently required, nor is it necessary. The advantage possessed by the dry sponge is in the increased absorptive power of the gauze. Gauze. — The writer has devised an apparatus in which to sterilize gauze for operations, either for hos- pital operations or o^^erations away from home. Chas. Truax, Greene & Co. kindly constructed this apparatus for me, as well as the furniture shown in the operating room in Fig. 9. It consists of a little stand which fits into the catgut sterilizer of the Boeckmann ajDparatus, or which can be set into any steam sterilizer (Fig. 13). Figure 13. Figure 14. The stand contains seven large test tubes, two inches in dicimeter, and about eight inches in length. In each of these tubes can be placed all the gauze of any one kind that will be required at any ordinary oi)era- tion, which is about two yards of sheet iodoform gauze. Ordinarily I have two tubes filled with iodoform sheet gauz(^, one with j^lain sterilized gauze, one with one- inch strip i(jdoform gauze cut the strong way of the cloth, one with two-inch strij) iodoform gauze cut in the same way, and one with a skein of silkworm gut and a skein i)i braided silk. These tubes are loosely filled and tlieir mouths closed with cotton. They are then Bu})jected U) steam sterilization in the Boeck- 78 mann or other steam sterilizer at maximum heat for one hour. They are then set aside and the following day they are again subjected to the superheated steam for one hour, and then dried by removing the cork in the top of the Boeckmann sterilizer so as to get the action of the diy heat. The contents of the tube are now thoroughly and permanently sterilized, and will remain so for weeks if the cotton stoppers in the mouth of the tubes are not removed. When I wish to preserve these tubes for indefinite use I have the nurse slip a sterilized rubber cap over the cotton and the end of the tube before removing them from the sterilizer. They may then be set aside for an indefinite time. When I wish to operate away from the hospital, I place the rack containing the tubes required into a metal box (Fig. 14), and that in turn is stored away in my instrument bag. Preparation of Operator and Assistants. — It should not only be taken for granted but should be insisted on, that any and all persons participating in the high calling of surgery should take a general bath, including the hair, every day. Dress. — For important operating, such as we have to deal with, special dress for the oj)erator and assist- ants is indispensable. Suits of white ducking or linen should displace the street apparel. Over this sterilized gowns should be worn. In this dress the operator can be comfortable and do hard work in a temperature of 80 degrees F. When he is through oi^erating all wet clothing, made so by perspiration and the fluids of the operating room, can be replaced by his (ordinary dry out-door dress and the reminders of the operating room are left behind. Preparation of Hands. — After the nails are filed .short and smooth the hands and forearms should be thorougldy scruV)l)ed for fifteen minutes in hot water with a stiff nail brush and plenty of pure soap. The water should be changed at least five times. The time should be estimated by an actual time piece and not 79 by guess work. A nurse should supervise this part of the work in imx3ortant operations, and report to the responsible chief any laxity on the part of any partici- pant. The spaces beneath the nails should be thor- oughly brushed and the undersurface of the nail scraped with a steel nail cleaner. After the soaj) and water scrubbing, the hands should be washed in alco- hol and then immersed in 1:1000 biohlorid of mercury solution, and this solution brought into contact with all irregularities by means of the hand brush. The hands should, finally, be rinsed in warm sterilized water. Before beginning the operation the hands should be rinsed in hot water which is placed in a basin close to the operator, so that it may be used from time to time during the operation. After the hands are once washed they should not be allowed to come in contact with anything before or during the opera- tion which is not surgically sterile. A7Tangetnent of OperatiiKj Room. — The steam or dry heat sterilizers containing dressings should be convenient to the nurse. Reservoirs of sterilized water, hot and cold, should be i)laced near the sponge table. Two large glass irrigators should be at hand. The table with which the Trendelenburg position may be obtained is necessary, and should be placed in an advantageous position for light and assistants. For a laparotomy, the arrangement of the furniture and par- ticipants of the operating room should be approxi- mately as follows: The table near the center of the room with the head of the patient near the chief win- dow. Anesthetizer at head of patient. Operator on right of table (from head). Chief assistant and assist- ants opposite the operator with the chief nearer the head of the table. The surgical nurse in charge of instruments at stand to right of operator. Nurse in charge at foot of table with sponge dish on small stand in reach of second assistant. Assistant nurse to her right, the latter to work sponges, and to attend to irrigators, sterilized water, etc. Superintending nurse without regular assignment, ready for emergency. To so left of operator, small table with sterilized solution for hands. Back of the assistants a similar table. Visit- ing physicians, admitted after everything is ready for the operation to begin, are arranged around the room out of reach of the operating corps, or any concerned in the oi3eration. If the case is one where a vaginal operation is required, the head of the patient is directed away from the window, and the patient in the exaggerated lithotomy position is placed with the buttocks directed toward the light. The limbs are supported on either side by two assistants. The operator sits at the foot of the table with the instruments at his right hand. To the left is the nurse with sponges and the irrigator. PREPARATORY TREATMENT OF PATIENT FOR LAPAROTOMY OR VAGINAL OPERATIONS. Kidneys. — The failure to recognize obscure kidney disease in jiatients before submitting them to a severe operation has been the cause of many avoidable deaths. We should not only recognize kidney difficulties in every case but we should also know when a case is laboring under some form of kidney trouble, whether that stage has been reached beyond which it is safe to proceed. It is not enough that the urine in any given case is approximately of normal quantity, of approxi- mately normal specific gravity, and that it gives negative results in tests for albumin and sugar. It is necessary to learn the history of the case, to estimate the sijecific gravity in a twenty-four hour specimen, to ascertain the amount of urea for twenty-four hours, and supplement this with a thorough and complete microscopic examination. In diabetes we should not operate. In interstitial nepl iritis when the disease is not far advanced an oi^eration may be risked with proper preparatory treat- ment. These latter cases arc^ tlie very ones which from their great difficulty of diagnosis are often neglected, and consequently disaster results. The importance of the suVjject must be my excuse for entering into 81 primary details. The following summarizes the signs of chronic interstitial nephritis: Lowered sj^ecific gravity of urine; patient arising at night to void urine (when there is no bladder or urethral disease to give rise to such a procedure); an enlarged heart with accentuated second sound; a tense pulse and diminished urea. Albumin is frequently absent. The diagnosis is doubly sure when hyaline casts are found. Every patient should be scrutinized in all these points. If the foregoing state of affairs exist to a marked degree I refuse to operate. If, however, with the above symptoms I find a normal quantity of urine, which does not show a reduced specific gravity under 1010 to 1014 and the amount of urea does not sink lower than six or seven grains to the ounce, if the patient is w^ell preserved generally without advanced heart disease, I am confident that I can operate with safety, if I can secure proper preiDaration. I i^repare these patients, first by placing them on an exclusive farinaceous diet w^ith miik and fruit for an indefinite number of days before the operation. A week or ten days before the operation a diuretic is added with instructions to drink large quantities of water, the object being to increase the daily quan- tity of urine from 60 to 100 ounces, in order to thor- oughly flush the kidneys and rid the patient of dan- gerous accumulations. With 60 to 100 ounces of urine flowing for several days, with the patient living on a non-nitrogenous diet, with the urea in improved proportion considering the diet, I feel safe in risking an operation. Dr. Charles W. Purdy, who has had an enormous experience in watching the behavior of kidney diseases under oj^erations, says in reference to chronic parcii- ch}jmafo}iS nephritis: "I see no reason why these cases, if unaccompanied with dropsy may not be ope- rated upon if carefully selected." Boivch. — In prei^aring patients for an ordinary laparotomy I begin preparations of the bowels two 82 nights before the morning of the operation. The first point is to seek thorough emptying of the bowels throughout their entire length. The second point should be to render their contents thoroughly aseptic and the third should be to impart to them a maximum tonicity. The bowels are emptied by means of mercurials and salines. The first night of ^preparation, six grains of blue mass are given. The next morning at 6 A.M., one drachm doses of citrate of magnesia are given every hour until the bowels move, or feel as though they would move with the aid of a small enema. This ought to insure a thorough movement of the entire length of the intestinal canal. If the movements are such, with the above treatment, to insure a thorough evacuation, and to start a free flow of bile, as indi- cated by the yellow glistening appearance of the stool, no further catharsis is necessary. The lower bowel should be thoroughly evacuated, however, by the employment of large enemas of soap and water, repeated four or five times during this second day of preiiaration. The last enema should be given late in the afternoon of this second day of preparation, if the operation is to be done the following morning, and the next morning if the ox)eration is to bo iDerformed in the afternoon. The bowels are rendei"ed aseptic by large doses of bismuth and salol. During the first and second days of jn-eparation, gr. x of salol and gr. XX of subnitrate of Insmuth should be given every six hours. The bowels are stimulated by means of carminatives, alcolujlic stimulants and strychnin. The second day of I^rei^aration 1 drachm doses of tr. of cardomon in one ounce of brandy are given every six hours. Strychnin is commenced three days before Iho o])eration iii 1-40 gr. doses every eight hours, andgradually increased in quantity until 1-20 gr. doses are given. The bowels should be kejjt in a thoroughly as(^])tic condition by feeding the patient a milk diet for two days lu'fore the ojieration. 83 External Preparations of the Patient. — The i&rst day of the preparation the patient should receive a thorough general bath and then be placed in clean clothing and a clean bed. The abdomen should then be rubbed with a saturated solution of permanganate of potassium until it is of a uniform mahogany color. This should be scrubbed off by means of a si^onge or brush and the application of a saturated solution of oxalic acid. A green soap compress should be bound on the abdomen, this latter to remain all night. Vaginal douches of, first, soap and water; second, 1 :5000 bichlorid solution, and third, plain sterilized water should be employed this first night. These should be repeated the night before the operation, and a last vaginal douche given immediately before the operation. The second night of preparation should begin with shaving of the abdomen and pubis, and should be followed by applying a bichlorid comjoress. Immediately before the operation, after this compress is removed, the abdomen should be scrubbed with green soap and hot water, this to be followed w4th alcohol or ether, and covered with an antiseptic towel until the incision is made. The bladder should be evacuated by means of a catheter immediately before the operation. Dress. — The patient is to be put in a long, loose, woolen night gown immediately after an operation, and is thoroughly covered, except the abdomen, with flannel blankets during the oi:)eration. Operation. — I am suspicious of an operator who operates on time. The best operators are those who oj)erate w^ell in the smallest space of time; this implies that the best operators are slow operators. An abdominrd incision should be a clean, true, unhag- gled cut, so that accurate coaptation is possible. Cold sponges should be employed on the external incision in order to contract the capillary vessels and check their bleeding without the necessity of forceps. Forceps should be employed, however, everywhere in abdomi- nal surgery that their use will save blood, because 84 most of our old-fashioned shock was caused by unnec- essary loss of blood. Keep the operative field free from oozing points if possible, even at the loss of a little time. The peritoneum is best opened between two catch forceps elevated so as to present a thin fold. After a small opening is made, the finger passed into the cavity should act as a guide upon which to complete the incision. The peritoneal edges should be attached to the integumentary edges by means of catch forceps, to j)revent its peeling off from the abdominal walls in the subsequent manipulation. In all j)elvic surgery of smaller tumors the pelvis should at this point be elevated by means of the Trendelen- burg table ; the elevation being sufficient to draw the bowels away from the field of operation, and to elevate the contents of the pelvis. Sterilized silk or catgut should be employed for any pedicle which it is safe to tie and drop. Catgut may be employed to close sim- ple peritoneal rents. Drainage should be employed in all cases where extensive enucleation has occurred, where there is a slow venous oozing from separated adhesions or where aseptic matter has in any way contaminated the peri- toneum. Drainage, in competent hands, never does any harm, therefore, where there is the slightest doubt, it should be employed. It has saved many lives, and made more comfortable those who might not have died without it, but who have 'been given the advantage of it. After my operation is finished, the peritoneal cavity is thoroughly dried; then if there has been at the operation a process of enucleation, leaving of neces- sity slight oozing points, or in cases where ordinary adhesions have bjeen separated, after drying the cav- ity as far as i)ossible, I place in the cul-de-sac a glass drainage tube and puirip out any remaining fluid. I next protect the abdominal contents from the abdominal wound with a large flat sponge, and insert the sutures^ after which I again pump the drainage tube. If there is more than a drachm of bloody fluid, 85 I leave the tube in until the sutures are nearly all tied and the sponge removed; then I make a last trial of the tube. If the fluid amounts to one-half drachm or more, and is bloody, I allow the tube to remain; if, on the contrary, it is nearly dry, or the contents is simply colored water, the result of flushing, if it has been employed, I remove the tube. What has been done influences one in regard to drainage. I almost invariably drain after it has been necessary to flush. I believe the peritoneum is satisfied, to an extent by the flushing, and will consequently neglect, in a degree, to absorb any remaining fluid. Ex- perience seems to sustain that argument. Mikulicz drain is almost indispensable in a limited number of cases. Cavities may be packed with gauze which can not be reached with glass drainage tubes. Hemor- rhages in cavities so packed will cease, when a glass drain would not avail. Operations are now possible with the Mikulicz drain which were impossible with- out it. The question about drainage is not, shall we drain, but how, and how often. To Prevent Intestinal Ohstruction. — In abdominal surgery one is constantly watching the behavior of the intestines. They are our prominent point of attack in our preparatory treatment, they are our greatest source of anxiety during the operation, and upon their management after the oi3eration much watchfulness is imposed. All of this anxiety is caused by our desire (with the exception of care against wounding when operating) to prevent obstruction. It, therefore, is a point in the technique of this work to which discussion may profitably be directed. The pathology of obstructions is well summed up by a valuable contribution on this subject by Dr. Ashton, of Philadelphia, from which I quote: "Adhesions between the intestines and raw sur- faces: a, to an omental stump; b, to the edges of the vaginal wound following supra-pubic or vaginal hysterectomy ; c, to a pedicle ; (/, to raw surfaces on the intestinal wall. 86 "2. Paralysis of the intestines. "3. Local spasm of the intestines. '•■4. Impacted feces. "5. Bands of inflammatory lymph. ''6, Adhesions between coils of intestines or between the gut and neighboring parts, due to trau- matic inflammation. "7. Kinking or twisting of the intestines, due to faulty technique. "8. Including the intestines within the loop of a suture of the abdominal wall, or between the edges of the abdominal incision. "9. Slipping of a coil of intestines through a slit or an aperture." Under the first head, "Adhesions between the intes- tines and raw surfaces," we must seek our remedy daring and following the ox3eration. Intestines should be handled and ex^Dosed as little as possible in order not to produce hyperemia or denudation of their sur- faces. An omental stumj^ of any considerable size should be selveged by inverting its raw edges with a running catgut, or with ligature. When denudations of the pelvic or intestinal pertioneum can not be rein- forced by a suj)erabandance in the neighborhood, care should be taken to carefully arrange the intestines in as near the normal position as jjossible. A pedicle of large size should be covered by securing over its end the peritoneal covering with a running stitch of cat- gut. Raw surfaces of any considerable size on the inte.stines should be covered with peritoneum if joossi- ble, with the edges well secured. Paralysis of the intestines may be avoided by emptying them thor- oughly previous to the operation of all irritat- ing matter (which may ferment and cause dis- tensi(m ) by rendering the contents aseptic by means of bismuth and salol, and the employment of full doses of strychnia to act as a muscular tonic. Car- minatives, such as wintergreen, cardamon, etc. may also be employed as antiseptics and inuscular tonics. During the oj^eration the intestines should not be 87 handled or chilled in order to avoid paralysis. After the operation, nourishment of non-fermentive and easily absorbable nature should be employed. The bowels should be stimulated to early action in order to keep them empty and avoid the beginning of dis- tention, which soon leads to f)aralysis. An early move- ment of the bowels, or free passage of flatus, assures a normal disposition of the bowels as regards location. If they adhere after such time, it will be in an advan- tageous, not cramped position. A flat sponge beneath the abdominal wound, after carefully spreading down the omentum and before the wound sutures are inserted, will avoid including an intestine within the loop of a suture, or between the edges of the abdominal wound. When ventral fixation of the uterus is practiced, great care should be exercised in disposing of the intestines in such a manner as to avoid their slipping through the opening left between the uterus and the abdominal wound. AFTER-TREATMENT. The immediate after-treatment consists in stimulat- ing the i^atient out of any tendency to nervous shock which may exist. She should be surrounded in bed with dry heat, and in hospitals x^laced on a water bed. If there has been any considerable loss of blood, the feet may be elevated in order to restore blood pressure in the brain. In severe cases of shock from loss of blood, it is well to bandage the blood out of the lower extremities by means of elastic bandages. A saline solution under the integument may assist to fill the blood vessels. Oftentimes the difficulty is not lack of fluids so much as lack of tone, which allows a patient to bleed to death, as some one has put it, "into her own dilated capillaries and venules." Here direct arterial stimulants and vaso-constrictor remedies are called for, as well as strong nerve stimulants. la these cases, I immediately order hypodermics of nitro- glycerin, strychnin and digatalin. Stimulating ene' 88 mas of whisky and warm water may also be given. What is done for shock should be done promptly, as patients who are allowed to go on for a few hours with a sub-normal temperature and high pulse, are with great difficulty restored. Dressing Glass Drainage Tube. — The glass drain- age tube, when it is allowed to remain, should be emj^tied with a syringe with a long rubber nozzle the first time in one hour. If the fluid is more than a drachm it should be dressed again in an hour, if a drachm or less, the interval between dressings should be increased one hour, and the same rule followed until the fluid is less than a drachm and of a light amber color, and the interval from four to six hours. At this time the tube may be removed. If it is left longer than thirty-six hours, a piece of sterilized gauze should be put in its place for six hours, when the latter is removed and the wound is closed with slight pressure and its closure is obtained by extra pressure of external straps. Care of Capillary Gauze Drain. — If capillary gauze drain has been employed instead of the glass drainage, the protruding gauze (from vagina or abdominal wound) should be kept abundantly covered with a pad of loose flufl'y gauze, and this should be changed as often as it becomes saturated with fluids. If all drainage ceases in twelve to twenty-four hours as indi- cated by dry dressings, the gauze packing may be removed. However, if drainage is free and the patient is normal it may remain forty-eight to sixty-two hours. When it is possible this drainage should have its exit through the vagina. After it has been removed a loose gauze packing should be placed over the wound. Dressings. — The wound is closed with silkworm gut, including all parts of the wound edges, and dusted with sterilized iodoform, and the dressing is a thick one of iodoform gauze, held in place by adhe- sive straps tight enough to take the strain off the sutures without jjuckering the integument. Over this is i)laced a liberal allowance of absorbent cotton. 89 and all retained with a binder. The dressings are not disturbed for four days unless there is pain or tem- perature. At the end of the fourth day the dressings are carefully removed, and the wound is thoroughly but carefully washed with equal parts of 95 per cent, alcohol and 1:5000 bichlorid solution. Iodoform is again applied and the dressings renewed. The seventh day, t>efore the stitches are removed, I again have the wound washed in the same manner and, after their removal, dressed as before. In vaginal operations the vaginal wound is dusted with sterilized iodoform and the vagina loosely packed with strij) gause. It is removed m forty-eight hours and after twelve hours vaginal douches of bichlorid of mercury solution followed by plain water are em- ployed once or twice daily. Botvels — If flatus has not passed freely, per rectum, in twelve hours by the simple emj^loyment of a rectal tube, I employ the "one, one, one" enema, one ounce, of sulj)hate of magnesia, one ounce glycerin and one ounce water. If this does not start the gas in two hours, I order it repeated in double quantity. If this enema is not retained, and flatus has not passed, I order an enema of soap and water one ]3int, with one- half drachm of turpentine. If they are still obdurate, I begin one-half grain doses of calomel in ten grains of bicarbonate of soda, given every two hours for four doses, or until gas passes, alternated with drachm doses each of gran, citrate magnesia and sulphate magnesia in an ounce of water. Following these rem- edies in one hour, another "one, one, one" enema is given. It must be an obstinate case indeed that will not yield under the above remedies. If the stomach is irritable and will not tolerate the bicarbonate of soda, the calomel may be given dry on the tongue. Other salines may be substituted for the above if they are objectionable. The bowels should be moved from above on the fifth day with small doses of some effervescing salt, or, if required, a more vigorous laxative. 90 Diet. — First week, fluids; second week, semi-solids; third week, semi-solid and solid food in small quanti- ties: fourth week, good substantial food, with a few curtailments. As soon as the patient is out of the anesthetic, I begin to give hot water in teaspoonful doses as often as every fifteen minutes. If the stom- ach tolerates this, the quantity is increased to one-half ounce, and the interv^al may be increased in length. If the patient is nauseated and the hot water causes vomiting (and it should be hot water), or increases the nausea, it should be withheld. When the patient can take the hot water, and still complains of thirst and begs for cold water the nurse is instructed to let her rinse her mouth with cold water. Ginger ale is a good alternate with water for the first twenty-four hours. After twelve hours, drachm doses of peptonized milk may be sandwiched with the water. If pepton- ized milk is offensive, plain sterilized milk may be substituted, or sterilized milk and lime water. Milk in some form, I feel to be the most perfect food. It should be increased every hour until ^- ounce doses are given by twenty-four hours, to one ounce by forty-eight hours, and to two ounces by the end of sixty-eight hours. Barley water may be alternated with the milk Later, the monotony may be relieved with the meat and shell-fish broths, thin gruels, etc. The fourth or fifth day the patient may be allowed to extract the juice of broiled beef by chewing it: the fiber, of course, should be rejected. Tea may be given the second or third day as a relish. Orange juice, and the juice of other fruits, may be given in small quantities the third or fourth day. Rules can not be laid down in regard to the diet of these patients, general princi- ples only can be hinted at. They)atientBhoukl beseen each day and her wants studied. If stimulants are required, one of the best is good brandy. Chami^agn© is all right if its sweetness dcjes not make it objection- able. If i)atients are unable to retain enough by stomach to properly nourish them, enemas of either milk or stimulants should be resorted to. 91 Getting Up. — Uncomplicated laparotomy cases are gradually bolstered up until they can sit in a bed with a bed rest at about the fifteenth or sixteenth day, sit up in a large chair at the twenty-first day, and leave the hospital from the twenty-eighth to the fortieth day. 92 LECTURE VII. THE author's operation OF VAGINAL LIGATION OF THE BROAD LIGAMENT AND OTHER MINOR OPERATIONS. Vaginal ligation of the contents of the base of the broad ligaments, for the cure of fibroids of the uterus, was devised and performed by me as a new and original operation Nov. 15, 1892, and was described and pub- lished in the April number of the American Journal of Obstetrics in 1893. In the January number of the American Journal of Obstetrics, 1894, I reported six cases treated by the new operation. The operation as originally described by me is as follows: The ligation of more or less of the broad ligament of the uterus, with its vessels and merves, the extent of the ligation depending upon the result sought, from a simple ligation of the base of the liga- ment, including the uterine arteries and branches of both sides without opening the peritoneum to a com- plete ligation of the ligament of one side, including both uterine and ovarian arteries, with partial ligation of the opposite ligament without opening the peri- toneal cavity, if possible, but by doing so if necessary. The results sought in the operation are, first to check uterine hemorrhages by cutting off blood chan- nels, and secondly to produce atrophy of the fibroid by, 1, depriving it of nourishment through the blood ves- sels and, 2, by changing the nutrition of the uterus by interfering with its nerve supply. Immediately after publishing my first article on this operation there were two claimants for priority; Dr. Walter B. Dorsett, of St. Louis, and Prof. S. ys Gottschalk, of Berlin, Grermany. Dr. Dorsett, in a letter to the American Jonrndl of Obstetrics, claimed that he had suggested a similar procedure to my oper- ation in an article he published in the St. Louis Cour- ier of Medicine in 1890, the article bearing title of "A Case of Atrophy of the Female Genitalia fol- lowing Pregnancy and remarks." In this article he made the following observation: "I believe that in the treatment of uterine fibroid . . . to ligate the uterine artery would not be an unscientific pro- cedure. On the contrary the more I have thought of it the more I am inclined to believe that it would be the most certain mode of treatment." Dr. D.^r- sett, while advancing the theory, had not at that time carried it out on a living woman. Prof, Gottschalk based his claim of priority on an article read by him at the Brussels Congress, Sept. 16, 1892, with the following title: " Die Histogenese und Aetiologie der Uterusmyome." In the latter paragraphs of this article he casually suggested liga- tion of the uterine arteries and stated that he had performed the operation twice. This is what he said: "The bilateral ligation of the uterine arteries ap- pears to be the therapeutic measure in this regard for the earliest incii3ient stages of myoma. This offers no difficulties in its technique; it is easily performed in a few minutes. . . I have already performed this ligation in two cases in which I was able to early diagnose the development of multiple myoma with best results." Thus these two men both suggested tying the uterine arteries for the cure of fibroids and at least one of them (Gottschalk) jjerformed the operation twice before I described my operation. This would definitely decide the question of priority in their favor if the operation they suggested was identical with mine. Their operation is not identical in theory, in execution, or in description with mine, and therefore their claim of priority for ni}-^ opera- tion can not be substantiated. 94 The operation suggested by these men simply in- ■cludes the ligating of the uterine artery from the vagina, while, 1, I ligate in all cases, the whole base of the broad ligament, in order, a, to occlude not only the main channel of the uterine artery, but all collateral branches; 6, in order to destroy the func- tion of the nerves as well as the arteries of nutri- tion; c, in order to diminish nerve reflexes. 2. I include, in desperate cases, not only the base of the broad ligament with the uterine artery and branches in my ligatures, but when practicable ligate high enough on one side to take in the ovarian artery. 3. I advise accomplishing this result, if possible, without opening the peritoneal cavity, but by doing so, if necessary. TECHNIQUE OF OPERATION. The preparation of a patient for vaginal ligation of the broad ligaments of the uterus should be sim- ilar to that demanded for vaginal hysterectomy, as described in my Lectures VI and IX. Ether is used as an anesthetic and the patient is placed on the operat- ing table in the exaggerated lithotomy position with buttocks brought to the end of the table, with an assist- ant on either side to support the limbs and hold the vaginal retractors. A broad, short vaginal retractor above and below exposes the cervix, which is trans- fixed with a strong silk ligature to be employed in handlinLc the uterus. The uterine canal is dilated and the uterine cavity curetted with a dull curette and thoroughly irrigated with 1:1000 bichlorid solution and then loosely packed with iodoform gauze. This procedure cleans the uterus and makes it impossible for the vaginal wounds to become infected by a septic uterine discharge. The uterus is now drawn down in order to jjut the broad ligaments on the stretch and then drawn to the right side so as to expose the left vaginal vault. The mucous membrane of the vagina at the utero- vaginal fold on the left side is tlieu^ caught with a tenaculum and incised with a i)air of 95 curs^ed scissors. One blade is allowed to enter beneath the mucous membrane and a curved incision one and one-half to two inches long is made over the broad ligament and at right angles to it (Fig. 15). By means of the index fingers of the two hands the oper- ,^^'*i-/'.., . ''JnW Figure lo. ator now separates the vaginal tissue from the broad ligament and carefully separates the broad ligament in front from the bladder for a height of two inches and laterally for nearly the same distance (Fig. K)). The bladder should be carefully separated in this way in order to avoid the danger of wounding the organ, 96 and by pushing the separation laterally the ureter is forced out of danger. One then carefully separates the broad ligament posteriorly to the same height as in front, without, if i^ossible, penetrating the peritoneum. Now, by passing one finger behind the other in front, the whole base of the broad ligament, representing two- FlGURE 10, Figure 17. thirds of its bulk, can be grasped (Fig. 17) foradistance of an inch to an inch and a half from the uterus. In this grasp one can easily feel the throb of the main trunk of the uterine artery and occasionally several branches. The curved pedicle needle is then passed, 97 armed with No. 10 silk, strong pyoktaninized catgut or kangaroo tendon, and guided by the index finger of the left hand (Fig. 18) is made to jDenetrate through the broad ligament. The ligature is drawn through, the needle removed and the base of the broad ligament is thoroughly ligated at a distance of one inch or more from the uterus. The ligature is cut short, leaving it Figure 18. Figure 19. buried in the tissues. The other broad ligament is treated in the same manner; the vagina is well steri- lized with bichlorid solution and the vaginal incision accurately approximated with fine antiseptic catgut so as to completely bury the broad ligament ligatures (Fig. 19). The handling string is now removed from the cervix, and the end of the gauze strip packed in 98 the uterus is tied to another strip and the vagina is filled loosely with a gauze drain. The after treatment of these cases is very simple. The vaginal and uterine gauze is removed tho second or third day, and twice a day thereafter a bichlorid vaginal douche 1 :2000 followed by plain douche are given = Figure 20 shows the joosition of ligatures when only the base of the broad ligament is ligated. Figure 20. SELECTION OF CASES. Interstitial fibroids of the uterus of moderate size are the cases in which the best results will be o})tained by this operation. Subi:)eritoneal fibroids sijringing from the fundus of the uterus especially would scarcely be benefited to any great extent by depriving the lower part of the uterus of its nourishment. Neither would one expect to obtain any lasting ben- efit from this oj)eration in cases of pedunculated sub- mucous fiVjroids. On the other hand, in true intersti- 9U tial growths depending upon the whole uterus for their nourishment, cases where the tumor is the uterus, and these represent 75 per cent, of all fibroids of the uterus, wherever it is possible to tie the base of the broad ligament from the vagina, this operation may be expected to accomplish prompt and decided relief of symptoms and a rapid reduction of the tumor. The cases in which the most satisfactory results must be exj)ected are incipient or small fibroids of the in- terstitial variety which show themselves late in the menstrual life. Here, we have a uterus which is small enough so that it has not risen above the brim of the pelvis, one which can be easily reached from the vagina so that its broad ligaments are accessible from below. Such a fibroid, too, from the age of the patient will reach a state of quiescence as soon as the menopause is established. In such cases, then, a major operation is particularly undesirable, because it is not imperatively demanded and because of a reasonable chance of relief at the approaching change; on the other hand the symptoms (with severe hemorrhage usually as the principal one) are such that immediate relief is earnestly sought, if one can be reasonably certain of obtaining it without submitting to a dan- gerous and radical procedure. These are ideal cases for this operation. Another class of cases in which this operation has been employed with gratifying success and in which it will j)robably find favor with the most radical oper- ators, are those of continuous and profuse hemor- rhage in which the desperateness of the drain is such that the patients are depleted to such a degree, that no radical procedure can be thought of, until a minor operative procedure has checked blood waste and recuperation is accomplished. My fourth and sixth cases were like the above. In the fourth case hemor- rhage was very profuse and the patient was completely exsanguinated and so weak that she had not been out of bed for several months. Some time before I deter- mined to submit her to my operation an attempt had 100 been made to remove the appendages, or, if possible, when the laparotomy was in progress, the uterus. From complicated adhesions and the weakness of the subject neither operation was possible after the abdo- men had been opened. The tumor was large and the elevation of the uterus in consequence was great, and it was with the utmost difficulty with the aid of the most competent assistants, that I finally succeeded in ligating thoroughly the base of each broad ligament. Both ligaments contained several arteries, some of them as large as the normal radial artery. They were all tied in mass. Hemorrhage stopped from the instant of tying the last ligature and it has never recurred. It has now been over three years since I operated on this case. The uterus has reduced until it is but slightly larger than normal. The woman (I examined her but a few months ago) is perfectly well. She has a slight menstrual flow each month, and is free from pain. Case six was of a severe hemorrhagic nature in a typical interstitial fibroid of three by five inches in diameter. The woman was too weak and dei^leted for a radical operation. I did my operation on her and the result was marvelous. In three months' time she had recuperated so that any radical ojjeration might have been done without danger. Dr. Humiston, of Cleveland, reported to me a case in which he used my operation as a procedure of last resort, in a patient nearly moribund from hemorrhage. She was so weak that he only attempted ligation on one side. The woman stopped bleeding instantly and eventually recovered. Hence, the operation may with propriety V)e employed as a rational temporary expe- dient in desperate cases of whatever variety, where uterine blood loss is conspicuous. CASES. In selecting cases for this operation I have been very careful. In the majority of them I have oper- ated on. there seemed no alternative. All were des- 101 perate ones, like cases 1, 2, 3, 6 and 8, or they would not submit to a more radical i^rocedure, and milder means, as electricity, ergot, etc., would not accomplish satisfactory results. I have been more conservative in adopting the operation, I am afraid, than the results in the few cases I have o^Derated on would justify. One reason for not adopting the operation in a larger number of cases is that I wished first to learn of the remote results. It is now over three years since my first operation and most of the operations which I have performed were during the first year. I have, therefore, a three years' history to analyze in the majority of my cases. In the following report there are no instances in which, at least, a year has not elapsed since the operation. Case 1. — This was an interstitial fibroid in a maiden lady 36 years old, in size extending above the umbilicus. The hem- orrhage was exhaustive and the patient greatly reduced in consequence. Her heart was hypertrophied and her con- dition was such that no surgeon with a proper care •for his statistics or his patient's life would have ven- tured a hysterectomy. She was operated on by my oper- ation Nov. 15, 1892. The hemorrhage decreased about one- half for several months after the operation. The tumor in the first four months materially decreased in size. In May, 1894, the hemorrhage is reported much modified, and no longer a source of alarm. The patient at that date considered her condition greatly improved, hemorrhage cured, tumor materially reduced and pressure symptoms subsided, March 12, 1896, four years and three months after the operation the patient reports herself well. The original fullness produced by the tumor she can no longer feel. No pain. The last flow- ing of any consequence was November, 1894. Since then the flow has been very slight until last July, when it practically ceased. "I have color in my lips and cheeks. I walk two miles or more every day," she writes. This report is certainly very gratifying. Case 2. — The second case was a married woman 40 years of age who had been under electrical treatment for a hemorrhagic myofibroma of the uterus. The galvanism decreased the size of the growth but did not materially lessen the exhaustive hemorrhage. The tumor was of the interstitial variety and the uterus appeared the size of a three months' pregnant uterus. When the patient entered the Woman's Hospital for operation December, 1892, she had been having almost contin- uous hemorrhage for several months. Upon exposing the 102 uterus with the retractors at the time of the operation, the cer- vix was large, blue and vascular. As the vagina was large the operation was very easily executed. The ligature on the left side included fully two inches in width of the broad ligament at a distance of at least an inch from the uterus. When I tightened this first ligature one of the spectators, a well known gynecologist, called my attention to the fact that the cervix had perceptibly paled in appearance. The broad ligament was easily exposed on the right side, and fully as much of it ligated as on the left. If there had been any doubt of the procedure affecting the vascularity of the uterus, it vanished when the second ligature was tied. The cervix immediately paled until it was nearly as white as a piece of cartilage. The covering of the broad ligament was so loosely attached in this case that I could easily feel the main channel of the ovarian artery, and it would have been an easy matter to have included it in the ligature. After over three years I can promise this case a perfect cure. The uterus has reduced to normal size. The hemorrhage has ceased completely. All pain has disappeared. A slight menstruation, normal in quan- tity, occurs each month. The patient's health has improved so, that from a state of almost complete invalidism she is transformed into to a strong healthy woman. The improvement has been progressive from the day of the operation. I have seen this case within the month (March 1896). Cane 3. — This patient was operated on in January, 1893. She had an incipient interstitial fibroid of two years' standing which was profusely hemorrhagic in nature. I tied the base of both broad ligaments including the uterine arteries and their branches. The relief was immediate. The menstrua- tion for the next four months was scanty. The patient gained in health and strength rapidly. The tumor, which was the size of a four months' pregnancy at the time of the operation decreased markedly in size within three months. Four months after the operation I lost track of this case, as she lived m a distant State and neglected to keejj me jjosted. Her last letter gave a rejjort of perfect health. CVi.sY:! 4. This patient had a large, bleeding fibroid filling the I^clvis, which extended to the umbilicus. The uterus and appendages were firmly adherent and immovable. Laparotomy had been attempted on the case, with the object of removing the appendages or the tumor. The abdomen was opened, but the adhesions and unusual complications rendered it impossible t() remove the tumor or even accomi)lish the oblation of the appendages. The patient was so unusually reduced from loss lOi of blood at the time of my operation that she had not been able to be out of bed for three months. I operated on the jjatient in January, 1893, at the Post- Graduate Medical School of Chicago, The operation was accomplished with great difficulty because of the large size and immovability of the uterus. Finally, however, after consum- ing more than an hour in time I succeeded in ligating thor- oughly the two broad ligaments well above the uterine arteries and their branches. In June following I made the following report on the case : "The flowing ceased immediately and the patient was relieved of her drain for over two weeks. She then had a few days' flowing, which resembled an ordinary menstruation. She has rapidly and steadily improved since that time. She has men- struated regularly but scantily, and without pain. She can at this time (June, 1893), five months after the operation, attend to her duties as a housewife, and considers herself cured. The tumor has become reduced in size until it is no longer notice- able as a deformity, and so that the patient herself is no longer conscious of its presence." Since the foregoing report was written in June, I have seen this patient several times, the last time within the month. The patient was then examined by several physicians, one or two of whom on inde- pendent examinations, failed to notice any abnormal enlargement. The uterus is still somewhat larger than normal, but is not more than three or four inches in diameter, while the testimony of at least three exper- ienced diagnosticians will bear me out in the estimate that its former diameters were not less than four and a half by eight inches. The patient is in good health now, Jan. 1, 1895; menstruation is regular but scanty, and she is free from pain. The patient, so far as I know, has remained well. Case 5. — This case was a woman with an interstitial fibroid about three by five inches. She was about 30 years of age, and the growth had been noticed for three years. Her principle symptoms were profuse menorrhagia with severe menstrual pain. The case was referred tomeby Dr. F. H. Greer, of Colum- bus, Neb. I did my operation on the woman Jan. 8, 1893. She had a little subsequent temperature, and one month after the operation the ligature sloughed from the left broad ligament. Four months after the operation Dr. Greer reports the woman V(^ell. "Menstruation scanty, no pain. Fibroid diminished in size until the uterus is about normal. Patient claims that she 104 is cured." This report was made in June, 1893. I iiave been unable to get any history subsequent to that date. Case 6*. — This was the wife of a physician of more than ordi- nary abihty and reputation. The patient was about 36 years of age, slightly above the average height, with well-proportioned frame, but poor in flesh, with a skin blanched and a body almost exsanguinated. The uterus was about the size of a three months' gravid uterus. The tumor was uniform and evidently interstitial. The uterus was in normal position. The cervix was nearly two inches in diameter, the os patulous. The history of the growth dated back, undoubtedly, several years. The patient had borne no children. The menstruation had for nearly two years increased in quantity and duration, until now, while coming with absolute regularity, it lasted fifteen days, and that in spite of vaginal and uterine tampons, the re- cumbent position, ergot, hydrastisand the rest. She flowed each month until she was completely exhausted, scarcely recovering in the next thirteen days sufficiently so that she could assume the upright position without fainting. Accompanying this unusual discharge was uterine pain, which in its severity brought the patient to the point of unconsciousness. During the four days in which the woman could drag herself around in the latter part of each intermenstrual period she did so with the greatest discomfort on account of the pressure and neuralgic pains of the pelvis. Upon examination of the broad ligament from the vagina the finger could detect on either side the large, pulsat- ing artery as it fed the tumor. The latter was movable, the appendages apparently normal, the broad ligaments accessible. In fine, here was an ideally typical case — a hemorrhagic fibroid of the uterus, a bed-ridden patient, an authentic diagnosis, an unusually interested physician to carefully watch and estimate the result, and one who enthusiastically demanded a trial of the new operation. Under the circumstances it seemed to me that much depended upon this case, as though the fate of this oper- ation must necessarily be more than usually linked with this particular patient. I operated on this case Aug. 2, 1894, at the Chicago Hospital, with Dr. Robert Dodds and Dr. Oksschct as assistants. The left broad ligament was carefully dissected from the peritoneal covering behind, and from the bladder in front, until fully two thirds of it could he grasped by placing one finger behind it and another finger or instrument in front of it. When {.'r.ifif;ed in this manner several beating branches of the uterine art<-ry, together with the main artery itself could be detected. This entire mass was then ligated in two sections with No. 12 braided silk, the silk cut short, the parts irrigated and the vaginal wound closed with catgut. After treating the opposite side in the same manner, the vagina was cleansed and loosely jjacked with iodoform gauze. When the operation was finished the throbbing arteries, which could be distinctly felt before, 105 could no longer be found. The cervix, which was large and prurplc previous to the operation, became pale and cartilagin- ous in appearance as soon as the ligaments were secured. The patient remained in the hosiDital three weeks. The first menstruation was due the day following the operation. It began the next morning, but was so slight and painless that the patient would not believe that it was her menstruation until several days had elapsed and no other flow apjDeared. It lasted about three days and was barely perceptible; absolutely no pain. The after treatment consisted in vaginal douches after removing the gauze, light diet and the recumbent position for two weeks. August 30, the second menstruation reappeared; there was a little of the old pain, but not sufficient to require anodyne of any kind; the flow was half the usual amount and lasted six days. September 28, the third menstruation appeared; the amount was normal in quantity, lasting but four days; the pain was slight. October 26, the fourth menstruation appeared; the amount normal in quantity, lasting but four days; the pain was slight. The patient was seen and examined by me just before the last menstruation. She had gained several pounds in flesh, her cheeks and lips were red and she was a i^icture of health and robustness. Her feelings were in accord with her appearance, as she enthusiastically assured me that she felt perfectly well. On examination I found the uterus was reduced in size. It was little, if any, larger than normal. Its bulk had decreased one-half. The cervix was small and normal. No arterial pulsa- tion could be felt in either broad ligament or around the vault of the vagina. The next report I received was in January, 1894: " I have to report," the husband says, " that Mrs. X. menstruated from December 19 to 21:. That the amount was about the same as before, /. c, slightly above the normal. Pain rather excessive for two days (possibly due to rheumatism and neuralgia). After flow had ceased I examined and found liGfature in 105 vagina and also small sinous opening to left side of cen'ix. Since then ihere has been slight discharge from same. She had been suffering some pain at that point, no pain since ligature came away." He adds enthusiastically: ''Taken all in all, the result so far is a grand success." Jan. 17, 1894, he writes: " Mrs. X. is up to-day (the fifth day) after the easiest menstruation she has had in her life; pain moderate and only one day. This in face of the right side still discharging. In the next two months I exjDect to have a well woman. The uterus is no^7 practically normal." I have lost track of this patient entirely, and I regret that I am unable to complete so interesting a history. If the- husband of this patient should read this report I hope that he will communicate with me. Case 7. — Mrs. S., Denver, Colo., aged 35, uterus about double the normal proportions, containing two or more centers of de- velopment and an extremely hemorrhagic tendency, was the seventh case operated on. The case had been treated unsuc- cessfully by curettement, electricity and the ordinary remedies for checking uterine hemorrhages. The uterus was retroverted but free from adhesions. The patient was prepai;ed carefully, and at the Woman's Hospital, on Nov. 11, 189.3, 1 ligated the base of both broad ligaments, and shortened the round liga- ments. The uterus was drawn well down, and each broad ligament, after incising the mucous membrane covering them in the vault of the vagina, was dissected free from the bladder and rectal attachments and then ligated with two strong liga- tures. These ligatures were placed high enough to include tho uterine artery, all its Ijranchcs, and all of tho contents of the base of each broad ligament. The ligatures were cut short after they were tied, the mucous membrane of the vagina was reunited with a running catgut ligature, and the vagina jxicked with iodoform gauze. The round ligaments wore then short- ened and the uterus left in a position of anteversion. Three days later tho gauze was removed from the vagina, an anti- septic douche was given and a Smith-Hodge pessary was in- serted. The antiseptic douches were then continued daily. The first menstruation was duo four days after tho operation. It did not appear. The second menstruation also failed to appear, notwithstanding the fact that menstruation had ordi- narily been exhaustive. One of the wounds caused in the operation for shortening the round ligament suppurated, and obliged 107 the i)atient to remain in the hospital until the latter part of January. Dizziness was complained of about the time when the menstruation was due. This symp- tom continued with different degrees of severity for some time, gradually disappearing. February 13, three months after the operation, the first flow ap- peared. The patient writes: "First menstruation came on the 13th of this month, without pain, but quite profuse for first two days. Since then has con- tinued, including to-day (the 18th). Discharge light." March 19, 1894, the patient reports: ''Am feeling fairly well this month. Had pain in back with last menstruation, which commenced March 13. First three days quite profuse; last four days very little No dizziness this month." Aj^ril 18, she writes: " Menstruation came on four days in advance of schedule time; continued one week. Am in fairly good health." December 14, 1895, two years after the operation, the husband writes that his wife suffers considerably with vertigo, especially severe immediately before menstru- ation. •' The operation performed by you has in a measure been successful, as the menstrual discharge is much less than before the oi^eration and the womb is in much better position." March 26, 1895, the husband writes: " Her men- struation is not i^rof use and she has less pain; her general health about the same" (as in her last letter). " I think the riding of the bicycle improves her gen- eral health and strengthens her in those parts wherein she is weak." Cases. — Mrs. Z., Muscatine, Iowa. About 35 years of age. No children. Multiple fibroid of the uterus approximating in size a four months' pregnancy. Hemorrhage profuse, followed foi a week by excruciating pain. Patient became extremely exsanguinated at each menstrual period. Frequently the flow- ing would last for two weeks. The uterus had been curetted. Electricity failed to control the hemorrhage and only |)ar- tially modified the pain The irregularity of the uterine canal undoubtedly accounted for the failure of the electricity. Nov. 28, 1893, the patient submitted to my operation for liga- tion of the broad ligament. The tumor was developed more to the 108 left side into the left broad ligament. I succeeded in separating the broad ligament for a height of two inches. On the right side a large double ligature was employed, while on the left side first a double and finally a second one higher and farther away from the uterus was applied. The ligatures were cut short, the vagi- nal vault closed with catgut and the vagina packed with iodo- form drain. The first menstruation was due three days follow- ing the operation. A slight watery discharge occurred instead of blood. Two days following the operation the patient com- plained of pain similar to that which ordinarily occurred after menstruation. Feb. 1, 1894, the patient's husband writes : " She commenced her menstruation Januaj-y 25, and it was continued until to-day, February 1, one day less than last time. Had one day of some pain ; not bad. She is getting stronger and can get around the house without being very tired, although she has not yet ventured out." February 26, the report is: "Mrs. Z. was sick this time six days, the same as last time. Had considerable pain two days which was very severe, the same as she complained of before the operation. She is get- ting along very nicely. She is now able to go out, and takes a walk every day. ' ' March 28, the -husband writes : "I am ready to make another report, but not as good a one as I would like. Mrs. Z. was sick on time and the flow was very little compared to what it has been, iasting but three days, but she had a great deal of pain -some before she was sick, and it was quite bad for two days after the menstruation. . . . Every- thing seems to be working very well if she could only get rid of that pain." April, menstruation still decreasing in quan- tity ; the pain decreasing. " There was one day of pain," the husband writes, " and the flow amounted to but very little." May 6, he writes : "Mrs. Z. has been feeling splendidly all this last month. Last week was her time to be sick again. The flow did not amount to anything, just enough to show. . , . In regard to her general health, it is excellent. Eats well, sleeps well and goes out every day the same as other women. Has gained her natural amount of flesh and a little more," I examined the patient May 19. The uterus was re- duced in size one-half. Patient in perfect health. March 13, 1896, two years and four months after this woman's operation, I received the following report from her: " Since the operation I have gained twenty pounds or a little more up to date. My men- struation period is abtjut one-half the time and amount it was before the operation. The pain is very much less than I had before the operation, but it has not left me altogether. ... I have the strength of the average woman now, while before the operati(jn I 109 was comi^elled to be in bed over half the time. Be- tween my menstruations I enjoy as good health as any one could ask. . . ." Case 9. — Mrs. C, aged 41, a resident of Iowa, consulted me for a bleeding painful fibroid of the uterus in May, 189i. The tumor was interstitial, uniform in contour, enlarging the ute- rus to the size of a four months' pregnancy. The hemorrhage at menstruation was profuse and lasted six or eight days at a time. The menstrual periods were accompanied with consid- erable uterine contraction pains. The patient complained of a great deal of heaviness in the pelvis and pains caused by the pressure of the tumor. The patient was weak, rather exsan- guinated and nervous. I concluded that the case was a suit- able one for my operation. The operation was done May 19, 1894. The lower portion of the uterus was so large and filled the pelvis so completely that it was with a great deal of diffi- culty that I accomplished the satisfactory ligation of both broad ligaments. However, when the operation was finished I was well satisfied that both uterine arteries had been thor- oughly shut off. The patient improved from the first. There have been no more hemorrhages. I have examined the patient two or three times since the operation, once v/ithin six months. The tumor has decreased in size, but has not disappeared. The pains and pressure symptoms are much better. The woman is apparently a healthy woman and does very much as other healthy women. In reply to my letter of inquiry she said March 12, 1896, one year and six months after her operation: " Since the operation I have had but few hemorrhages, while previous to that I had them very frequently. I am now quite regular, though I never go to my full time — about three weeks. I have less pain, but the heaviness still remains. I am better in health and strength than before the operation." Judging from my other cases I expect this woman to gradually recover. My fear was, when I adopted this operation, that collateral circulation would speed- ily overcome the result of ligating of the blood sup- ply. Experience, however, shows that the results of the operation are greater the farther away from the operation we get. Case 10. — Mrs. S.. aged 35, a resident of the central portion of 110 the State, came to the Woman s Hospital in August, 1894, to consult me about an interstitial libroid. She had borne no chil- dren. The uterus was large, regular in contour, hard and about four by six inches in diameter. It was freely movable in the pelvis. The woman gave a history of severe monthly hemor- rhages which lasted anywhere from six days to two weeks at a time. Accompanying the flooding were severe contraction pains. The woman was bloodless, pale, weak and extremely nervous. In all other respects she was normal I did my operation on the case in August, 1894, with the assistance of the house staff of the Woman's Hospital. It was easily performed on account of the movability of the tumor and the looseness of the broad ligaments. September, 1891, the patient wrote: ''It is now six weeks since I have menstruated. The pains are not any better My bladder trouble (pressure) is much relieved." October, 1894; " I have menstruated since my last letter. The quan- tity and length of time was small. Had a good deal of pain the first two days." November 13, 1894. ' ' Menstruations three weeks apart. I flowed more than usual." December 17, 1894. "Pains some less. My changes came ' at the correct date, but was greater in quantity than it should have been " January 29, 1895. "I flow a great deal more than I think I ought. I have to change my napkins six or seven times a a day." March 25, 1895. "I was a little better my sick week this month. The flowing did not last so long as it did before my operation, but more than is right. My pains are gradually improving." May 27, 1895. "I flowed very freely and had a great deal of pain this month." Cane 11.— Mrs. Y., the wife of a very intelligent physician of Indiana, consulted me in November, 1894. She had an inter- stitial fibroid aVjout the size of a four months' pregnancy. She was 43 years of age. I operated on her Nov. 7, 1894. Both broad ligaments were tied, so as to include two-thirds of their bulk. This occluded the uterine arteries on lioth sides with all their anomalous branches. I have seen this patient several times since her operation and the uterus is gradually lessening in size and the x^atient's symptoms are subsiding. I expect this case to jjrove successful with a little more time. In reply to a request from me for a statement ot xji'ogress, the husband writes March 12, 1894, a year and four months after the oi)era- tion, as follows : "My Dear Doctor : - In reply to yours of yes- terday, I have to say that my wife, on whom you operated Nov. 7. 1894, is doing very well as far as the fibroid is concerned. It has decreased in size some;, not a great deal. The menstrual flow on two occasions was quite profuse, but the last two Ill periods have been very scanty only lasting three days, and only using one or two napkins in a day, whereas before the opera- tion she used eight and ten each day for four or five days. She suffers very little pain, in fact none for the last month. Before her operation she suffered constantly. Her general health has greatly improved, and she has gained ten pounds in flesh, is much more cheerful, and in fact improved in every way. . . My wife is now past 45 years of age, and I l^elieve if the tumor does not increase in size until after the menopause, she will entirely recover." Case 12. — Miss V., single, age 40, consulted me in November, 1894, on account of a painful bleeding fibroid. She was de- pleted to an unusual state, and her nervous system was a wreck. She had an interstitial fibroid with the canal of the uterus measuring four inches in depth. The uterus measured approximatelv three by six inches in diameter. The organ was movable. Hemorrhage occurred only at regular menstruation periods. At this time it lasted a week or ten days and was very profuse. Accompanying the flow was great prostration of the patient and also most excruciating pelvic i^ressure symptoms. This condition of affairs had been going on for months until the patient from blood drain and harassment of pain had been brought to a deplorable state of health. December 5, 1894, 1 ligated the base of both broad ligaments. The operation was accomplished with ease because the uterus was movable and the broad ligaments loose. The patient recovered nicely from the operation. The next two or three menstruations were much more normal, the quantity of How being very small and the pain scarcely perceptible. The woman was placed on tonics and urged in every way to increase her blood supply. Her nervous system reacted slowly. Her menstruations later became more profuse and was accompanied on several occasions by quite severe pain. While but a short time has elapsed since the operation the patient is gradually improving. March l2, 1896, one year and three months after the opera- tion, she writes: "The amount of menstrual flow averages about one-half the amount it was before the operation. Have gained a little in fiesh. Have considerable pain. Still have nerves although under better control than formerly." This patient has improved in many ways. Dur- ing lier intra-menstrual periods she is compara- tively well and is able to go about and to do more work than she should attempt, whereas pre- vious to her oijeration she was unable to do much. While she had been neglected for a long time and her health had reached a low ebb, I can not but believe that she will gradually improve as a direct 112 result of the diminished flow. Her tumor decreased in the first four weeks fully one-third. It has not increased perceptibly to the patient since she left my care. Case 13. — Miss B., age 26, consulted me in January, 1895, for a bleeding intramural fibroid. The uterus was about five inches long and had a canal three and three-quarter inches in depth. The canal was a little irregular. In the fundus of the uterus could be felt two distinct centers of development, one on the anterior surface about two and one-half inches in diam- eter, and projecting from the main body of the uterus one and one-half inches. It was hard and had the unmistakable firm consistency of a fibroid mass. On the posterior surface of the fundus at its junction with the neck was a second center pro- jecting from the uterus about one and a half inches. This mass was irregular and was fully two inches in diameter. The symptoms which brought this patient to me were prolonged and exhaustive hemorrhages and uterine pains. The lady is a vocalist of unusual talent and these symptoms interfered seri- ously with her profession. The case was a typical one for hys- terectomy, especially as the left ovary was enlarged and cystic, but as that would involve the removal of the ovaries the patient objected to this because of the popular but unfounded fear that removal of the ovaries impairs the voice. I therefore decided to perform my operation on the case. When the patient was under the anesthetic I confirmed absolutely by bimanual manipulation my diagnosis as given above. Febru- ary 1, 1895, I operated on this patient. She left the hospital in two weeks. She did not have an unfavorable symptom. Men- struation practically ceased from the date of the operation. There was but the slightest show each month. No pain what- ever. In less than a month she was able to attend to her pro- fessional duties and was stronger than she had ever been. G^his fjerfect condition of affairs continued until aVjout Dec. 8, 1895, ten months after her operation. At this time I was called be- cause of a sudden attack of severe pain she had experienced in the left side of the pelvic region. The pain was accompanied with profound prostration and shock, I diagnosed ruptured cyst of the left side and advised a laparotomy. In making my examination I was surprised to find a perfectly normal uterus. I performed laparotorhy on this patient Dec. 28, 1895, and removed a ruptured ovarian cystof the left side and x^unctured a small cyst in the ovary of the right side. This gave mo an opportunity to examine the uterus which I had treated by my operation a little over ten months before. On the anterior por- tion of the organ corresponding to the location of the anterior fibroid described above 1 found buried in the wall and project- ing a half inch, a fibroid center one-half inch in diameter. On the posterior surface, corree ponding to the other center which 113 I palpated at the previous operation, was another center dis- tinct but even smaller than the anterior one. These were both exhibited to the house staff and physicians present at the oper- ation. The behavior of this case was most gratifying until the complication of the ruptured cyst arose. This fortunately gave me an opportunity of examining by direct sight the results accomplished by the first operation. I have no doubt but that those two fibroid centers would have been starved out eventually and the case actually cured without any further interference. General Summary: Thirteen cases operated on in which more than a year has elapsed since the operation : Case 1. — Age 40. Operation Nov. 15, 1892. Very large bleeding fibroid. Present condition : Tumor much reduced. Hemorrhages ceased. Patient well. Case 2. — Age 40. Operation December, 1892. Fibroid inter- stitial, size of three months' pregnancy. Profusely hemor- rhagic. Present condition: Tumor disappeared. Absolute cure. Case 3. — Operation January, 1893. Interstitial bleeding fibroid of two years standing. Four months after operation. Last report : Tumor reduced, patient much improved. Case 4. — Age 38. Operation January, 1893. Very large ad- herent intefstitial fibroid. Excessively hemorrhagic. Patient bed-ridden. Two years afterward : Uterus reduced almost to normal size. Hemorrhage ceased. Patient well and strong. Cased. — Age 30. Operation Jan. 8, 1893. Interstitial fibroid three by five inches in diameter. Profuse hemorrhage. Report four months after operation : Uterus normal ; hemorrhage ceased. Case 6.— Age 36. Operation Aug. 2, 1894. Interstitial fibroid. Profusely hemorrhagic and painful. Patient much reduced. Tumor three by five inches in diameter. Six months after operation much improved. No later report. Case 7. — Age 35. Operation Nov. 11, 1893. . Incipient inter- stitial bleeding fibroid. Two years after operation : Tumor reduced ; hemorrhage ceased. Case 8. -^ Age 3o. Operation Nov. 28, 1893. Painful, hem- orrhagic interstitial fibroid, size of four months' pregnancy. Two years and four months after operation : Tumor much dim- ished ; hemorrhage ceased ; pain less but not entirely relieved. Case 9. — Operation May 19, 1894. Interstitial, xjainful, hem- orrhagic fibroid. Tumor size of four months' pregnancy. One year and ten months after oxjeration : Tumor slightly dimin- ished ; hemorrhage materially reduced. Case 10. — Age 35. Operation August 1894. Tumor inter- stitial four by six inches in diameter. Hemorrhage and pain 114 excessive. Not much improved eight months after operation. Case ii.— Operation November 7, 1891. Tumor interstitial, hemorrhagic, painful and size of four months pregnancy. One year and four months after operation : Tumor decreased in size and hemorrhage ceased. Co.se 12. — Operation Nov, 1894. Tumor interstitial, pro- fusely hemorrhagic, painful, and three by six inches in diame- ter. One year and three months after operation : Tumor reduced ; hemorrhage less ; pain not improved. Case 13. —Operation Feb. 1, 1895. Tumor intramural, two centers of development two inches in diameter each. Pro- fusely hemorrhagic and excessively painful ; hemorrhage and pain ceased ; tumor nearly disappeared, as demonstrated by a laparotomy ten months later. MINOR SURGERY FOR SUBMUCOUS FIBROIDS. Pedunculated submucous fibroids may frequently be completely removed through the dilated cervix without interfering materially with the uterus. Un- less the tendency to pedunculate is well established however, and the center of development comprising the tumor is the only center of fibroid development to be discovered in the walls of the uterus as shown by careful bimanual palpation, it should be treated by hysterectomy either vaginal or abdominal. An excep- tion to this general rule would be when a peduncu- lated fibroid is discoverable either in the cavity of the uterus or hanging from the cervix with a long thin pedicle. In such a case the polypus should be care- fully removed from the uterus, even though there were other centers of development to be discovered. The uterus as a whole, here, could be dealt with in a later operation if the removal of the pedunculated mass did not sufficiently relieve the symptoms. The removal of an intrauterine i)edunculated fibroid is usually a simple procedure. If the pedicle is small and long and the tumor is in a position where it can be easily reached with forceps, it may be grasped in a strong vulsellum and the tumor twisted until the X)edicle is actually twisted in two. This can only be done with thin pedicles. If the pedicle is broad the uterus should be sufficiently dilated (the patient under an anesthetic) to expose the i)edicle, if 115 it is necessary to accomplish this the cervix may be divided as high as the vaginal junction. The mucous membrane of the pedicle should next be cut in its entire circumference. Then the remaining j)ortion of the pedicle composed of the blood vessels, connective and muscular tissue should be twisted in the same way that one proceeds to twist off a small pedicle. If the remaining portion of the pedicle is small it will give way by that treatment. If it is rather large and fleshy, after it has been twisted into a small bulk it may be grasped by a strong pair of curved pedicle forceps and the pedicle severed with scissors or a knife outside of the forceps. If the pedicle is very vascular the forceps may be left in place for six or twelve hours. If this does not seem necessary the forceps are removed and the uterus packed with iodo- form gauze. If the forceps are left on the pedicle, gauze should be packed around them. The forceps may be removed in six or twelve hours without dis- turbing the gauze. I do not favor attempting to enucleate a submucous fibroid of any considerable size if its principal bulk is buried in the walls of the uterus. Such a procedure is attended with considerable mechanical difficulty because of the position of the tumor in the cavity of the uterus; it is a difficult matter to secure hemosta- sis in such a location and finally one seldom reaches in such a procedure more than one of several centers of developments of the tumors which are situated in the uterus. In these cases a hysterectomy is more satisfactory. A cervical fibroid developing toward the mucous membrane, if pedunculated, should be removed in the same manner as that described for removing a pedun- culated intrauterine fibroid. A cervical fibroid of small size may be enucleated by incising its capsule, grasping the tumor with a vulsellum, and dissecting it from its bed. The cavity may be closed with buried antiseptic catgut sutures or it may be packed with iodoform gauze. 116 CURETTEMENT. In many cases of hemorrhagic fibroids much of the hemorrhage and leucorrhea is caused by endometritis. A safe and oftentimes beneficial treatment for such cases is thorough dilatation of the uterine canal and curettement of its mucous membrane. While it will not ordinarily have a direct curative effect it will fre- quently relieve disagreeable symptoms for a long period of time. The dilatation should be gradual beginning with Goodell's dilators and afterward exploring the anterior of the uterus with the index finger to discover whether there are any projecting masses into the interior of the cavity. After thor- ough dilatation with the cervix exposed and grasped with small vulsellum forceps in order to steady the whole organ, a sharp curette should be made to trav- erse all portions of the endometrium. This should be accompanied with some form of antiseptic in'iga- tion. The whole mucous membrane should be gone over at least three times with the curette, the canal then loosely packed with iodoform gauze, the vagina filled with the same and the patient put to bed for several days. The gauze should be removed in forty- eight hours. After that antiseptic vaginal douches must be given for several days LECTURE VIII. REMOVAL OF THE UTERINE APPENDAGES. Battey, Tait and Hegar independently conceived, performed and contributed to modem surgery the operation of removal of the uterine appendages. In 1865 Battey "conceived" but did not publish "the idea of producing an artificial menoj^ause for the remedy of disease." His idea was published in 1872. Hegar operated on the first case with the object of establishing an artificial menopause, a few days before Aug. 1, 1872, the memorable date of Tait'g first opera- tion for the same purpose. Battey did his first opera- tion just sixteen days later, or Aug. 17, 1872 Thus the time was ripe and three great men of three great nations, separated by thousands of miles, discovered the fact, independently of each other, and shook the tree of progress which has resulted in such an abun- dant harvest. The removal of the appendages for the cure of fibroids of the uterus is based on the facts: 1, that removal of the uterine appendages eradicates the part of the economy in which resides the organ or center of menstruation and produces an artficial menopause; 2, that removal of the uterine appendages accom- plishes a reduction of the direct blood supply to the uterus and thereby produces atrophy by depleting the organ. ARTIFICIAL MENOPAUSE. It is yet an unsettled question where the exact seat 118 of control of menstruation is located. It is not the province of this article to enter into the heated discus- sion as to whether this remarkable center lies in the ovaries or whether it is situated in the nerve structure of the Fallopian tubes. It is enough for us to know that the menstrual center, wherever it lies, is eradica- ted, in the maximum proportion of cases, when every vestige of both ovaries and Fallopian tubes is removed. It is well that such is the case, because it would be an awkward and incomplete operation which would seek to leave either the ovaries or the tubes. These two organs have a function which of necessity is incomplete without both of them. It would be difficult to remove the ovaries without interfering with the circulation and position of the tube. It would be equally impossible to remove the tubes without interfering with the circulation and function of the ovaries. Then, too, a much more secure and desirable pedicle can be obtained when both organs are included in a ligature than is possible if but one of the organs is selected. Then, as the function for which each of these small organs is designed is depend- ent upon both, and the removal of both is easier and therefore safer than the removal of one of them, and when we take into consideration the liability of either of these organs to become diseased, if not removed when opportunity permits, there seems to be no further reason why both organs should not always be removed when it is desirable to produce an artificial menopause. REDUCTION OF BLOOD SUPPLY TO THE UTERUS. In a previous article we discussed the blood supply to the uterus. We found that the organ depended upon two sets of arteries for its nourishment, the uter- ine arteries and the ovarian arteries (Fig. 21). The normal ovarian arteries are a trifle more than half the size of the uterine arteries. They supply the ovaries, the tubes, the fundus of the uterus and anastomose with the uterine arteries which course along the sides 119 of the uterus giving off frequent horizontal branches to the uterus. By referring to Fig. 21 it can readily be seen that the ovaries and tubes may be removed with- out including the main channel of the ovarian artery. Such a method of operating would deprive the removal of the appendages for the cure of fibroids of one of its chief features of benefit, viz., the reduc- tion of blood supply to the uterus. For that reason special care should be maintained by operators adopt- ing this procedure to include in all cases the main channel of the ovarian artery in their ligature. By Figure 21. tying this artery on both sides the large abnormally developed uterus is instantly deprived of one-third of its blood supply. Dr. Byron Robinson, after witnessing my operation of tying the broad ligament from the vagina, recog- nized the value of this principle of cutting off blood supply to fibroid uteri, and afterward applied one of the principles of my operation through an abdominal incision, after having first removed the appendages, by tying the uterine artery as it courses up the side of the uterus to join the ovarian artery. ]20 INDICATIONS FOR REMOVAL OF UTERINE APPENDAGES FOR FIBROIDS. But a few years ago this was the operation of selec- tion for the relief of uterine fibroids when an operation of the severity of a laparotomy was deemed a necessity. It is seldom performed at present except as an opera- tion of dernier ressort, when laparatomy has been instituted with the object of removing the tumor and uterus and, because of contraindications, the latter operation is found inadvisable. The reasons for this change of position are: 1. The operation of vaginal and abdominal hyste- rectomy has been so perfected that in patients of ordi- nary strength, with tumors without severe comi)lica- tions, the mortality of hysterectomy is not materially greater than that of double oophorectomy. 2. The operation of removal of the appendages fails about three times in thirteen recoveries to materially reduce the size of the tumor, and fails in one case in thirteen recoveries to produce an artificial menopause ; while hysterectomy on the other hand is absolutely sure of curing every case of fibroid of the uterus, which recovers from the operation both of hemor- rhage and tumor. This materially narrows the field of this operation which has done more to develojj modern surgery than any other discovery of modem time, except the dis- coveries of Lister. The very enlightenment which it has created helps to make it obsolete. The operation now, in the hands of expert abdominal surgeons, is limited to cases : 1, where for some reason the operation is dem}mded because of prejudice against sacrificing of the uterus; 2, in cases where for some good reason quickness of time in operating is desirable; 3, in cases where unusual complications are revealed when tlie abdomen is opened which make hysterectomy impracticable; 4, in cases of small bleeding tumors in weak women who are near the menopause; 5, in cases of small hemorrhagic fibroids in weak women in 121 whom laparotomy would not ordinarily be indicated but which, are complicated with disease of the appendages. THE OPERATION. An abdominal operation is properly divided into five parts: Incision, removal of pathologic material, drainage, closure of incision and dressing. The Incision. — After the skin has been prepared as described in Lecture VI, sterilized towels have been placed around the field of operation, the patient is thoroughly anesthetized with ether and the operating corps is in its place; the operator standing on the left side of the patient, with a sharp scalpel makes an incision from above downward in the median line, from about two inches below the navel to two inches above the upper margin of the pubis, an incision about three inches in length. This incision should be unhaggled and should extend in dej)th through the skin, superficial fasciae, the fat between the super- ficial fasciae down to the deep fasciae which immediately covers the muscles. In experienced hands but one stroke of the knife is necessary for this. If the hem- orrhage is but venous, sponges only are necessary to keep the wound dry. If there are any arterial points of bleeding they are caught in the points of forceps by the assistant. The operator by another stroke of the knife incises the white deep fasciae, and if this incision is through the linea alba, the subperi- toneal space is entered, as will be indicated by the bulging fat of this space. If the incision is to the right or left of the line the muscular coat of the abdominal wall will be exposed. The muscles are then separated by the handle of the scalpel in a stroke from above downward which brings into view the sub- peritoneal fat. The knife is carefully drawn over this from above downward, and this followed by a sweep of the scalpel handle separates the fat and subperito- neal tissue down to the peritoneum. The peritoneum is now caught in two catch forceps which are held up and separated laterally so as to present a sharp eleva- 122 tion of that membrane. This is carefully incised with the knife. When the peritoneum is opened it will be indicated by its sudden elevation in consequence of the entrance of air. An experienced operator will frequently open an abdomen carefully in thirty seconds. If it is done well it matters little if it takes five minutes. It is not necessary to seek for the linea alba if it does not happen to lie directly in the center of the superficial incision. It is more important that the wound should be direct and the different layers parallel than that the muscles should not be disturbed. When the peritoneum is opened between the forceps the index finger should act as a director above and below the opening and the perito- neum incised with scissors the full length of the wound, being careful not to wound the bladder below. Next attach the peritoneal edges of the wound at the center of the incision on either side to the deep fasciae with small catch forceps. This prevents peeling off the peritoneum from the parietes in any subsequent manipulations. E.Tjdorfdion. — With the index finger of the left hand I now make my exploration of the abdominal viscera including the appendages. First the uterus is sought as a central landmark. From the uterus the finger is first swept to the left side along the Fallo- pian tube from the horn of the uterus. Just below the tube and above the broad ligament is the ovary. The opposite side is rapidly explored in the same manner. The exploration takes into consideration the size and position of the fibroid uterus, adhesions, the condition of the appendages, the possibility or feasiVjility of removing them and any abnormal devel- opments. Ramovdl of the Appendages. — Our object, it must be remembered, in the removal of these organs must be to remove completely every vestige of ovary and tube and the thorcjugh ligation of the main channel of the ovarian vessel. When the uterine tumor is not large, or if it has not developed into the broad liga- 123 ment so as to spread out its folds and make it tense, it is an easy matter to ligate off the tube and ovary with one ligature. This is accomplished by lifting the tube and ovary with the loose broad ligament and making a pedicle of the infundibulo-pelvic ligament (Fig. 22 a), the ovarian ligament (6) and the Fallo- pian tube (c). The ligature No. 10 braided silk or No, 8 antiseptic catgut threaded in a round non-cut- ting needle is placed around the pedicle, never through it except as it ]3enetrates and surrounds a portion of the infundibulo-pelvic (Fig. 22 a) and the ovarian (6) ligaments in order to prevent its slipping Figure 22. over the edge of the stumi^. If the ligature is allowed to transfix the pedicle at any other place than through the firm ligamentous tissues of the two ligaments mentioned, it is liable to produce venous oozing into the loose subperitoneal tissue beneath the constric- tion of the pedicle, resulting in small hematomas which frequently prove troublesome. After the liga- ture is placed the ovary and tube are drawn well up and the strand of silk or catgut is tied firmly, first with a double twist knot and then two single twists and the ends cut short (Fig. 23). A pair of snap for- ceps is then placed on the pedicle outside of the liga- 124 ture and the pedicle is severed about one-fourth inch from the ligature, the stump cauterized or ren- dered sterile with some strong antiseptic, this anti- seiDtic removed by a moist sponge and the pedicle dropped. If the uterus is considerably enlarged or if it espe- cially develops into the broad ligaments, it is impos- sible to tie off the appendages of each side with a single ligature. This is because the loose folds of the broad ligaments of which the pedicle is ordinarily constructed, have been occupied by the enlarged Figure 23. fibroid uterus, and the ovary and tube are each flat- tened out on the surface of the tumor and are held fast by the peritoneum, which ordinarily acts as a mesentery to each, Fig. 24. Under such a disposition of affairs or any modification of it, the ovaries and tubes should be tied off' by first ligating the neck of the tube as near the uterus as possible after anchoring the ligature by a twist around the utero-ovarian liga- ment (Fig. 24 a); second by ligating the broad liga- ment outside the fimbriated extremity of the tube 125 Figure 25. 126 deep enough to include the ovarian artery, anchoring the ligature by a twist around the infundibulo-pelvio ligament (Fig. 24); third, after removing the tube and ovary the two peritoneal edges representing the broad ligament to which the tube and ovary are attached between the two ligaments already placed, should be united from one pedicle to the other with a running stitch of fine antiseptic catgut. This makes a perfect exsection of the apiDendages, and leaves the peritoneum perfectly closed with no tension on either of the pedicles (Fi^. 25). DISEASED APPENDAGES. All cases, unfortunately, are not typical like the ones we have described. We often meet with dis- eased appendages when opening the abdomen for the removal of these organs in cases of fibroids of the uterus. A pyosalpinx, or an ovarian cyst, or abscess of the ovaries are often encountered. Almost invari- ably when these things do exist, localized peritonitis has rendered them ad.herent to surrounding tissues, the uterus, omentum, intestines or the peritoneum of the broad ligament. When these complications exist, and we have decided upon the removal of the appendages for the treatment of the fibroid, we have before us the prob- lem of enucleation and excision of the diseasecl and adherent organs. The enucleation of an enlarged pyo- salpinx, or an ovarian abscess, or a tubal ovarian abscess, or adherent appendages the result of an old peritonitis where pus is no longer present, is accomplished in prac- tically the same way. When the abdomen is explored the abnormal condition of affairs immediately becomes api^arent. Frequently there is an inextricable mass; occasionally the outlines of the tube and ovary can be traced and they simply appear as enlarged adher- ent semi-fluctuating cysts; while rarely, the appen- dages, not materially changed from their normal size, will be firmly imbedded and adherent. I begin my enucleation in these cases, by passing 127 the index finger of my left hand, with the palmar surface directed forward, down behind the isthmus of the tube just as it is given off from the horn of the uterus, hugging closely the body of the uterus until I have reached Douglas's cul-de-sac. As a rule, at this place I will find a line of cleavage as indicated by the adhesions between the tube and the uterus and the ovary, and the intestines and omentum posterior to the ovary and tubes. This line of cleavage, which as it gives way feels like two pieces of strong paper which have been stuck together with fresh mucilage giving way before pressure of the fingers between them, can be followed rapidly, first with one finger, then with two or more, until the whole adherent tube and ovary are freed and lie ready to be ligated ofP in the palm of the hand. This is the happy result in the majority of cases. In a few cases, especially after long standing disease, the adhesions are strong and well organized. Here great care and patience must be exercised, in order not to go into an adherent bowel, or to the other extreme and leave a portion of the stroma of the ovary or a portion of the tube which may be just enough to prevent the menoi^ause and thus make our oj)eration a failure. Here, when the line of cleavage fails to yield readily, it is well to place the patient in the Trendelenburg position and separate the adhesions after exposing them to sight. With this precaution and the exercise of considerable care in manipulation it is seldom that one need fail to accomplish an enucleation. When these adherent masses are once dug from their beds the stumps, after ligation, should be ren- dered perfectly sterile by the application of the actual cautery or strong chemic antiseptics. The parts should then be dried, and where it is practicable the raw surfaces should be covered with peritoneum. Drainmje. — If there is oozing from the raw sur- faces caused by the enucleation, a glass drainage tube should be placed in the cul-de-sac of Douglas, the 128 lowest point of the pelvis, while the toilet of the peri- toneum is being completed and the abdominal sutures are being inserted. Before the abdomen is closed the tube should be pumped out in order to ascertain if there is more blood oozing from the peritoneal sur- faces than would naturally be taken care of by the IDeritoneum. If more than a couidIc of drams of pure blood accumulates in the few minutes that are required to make the toilet and insert the sutures, the tube Fkjure 26. should be allowed to remain, and the sutures tied so as to enclose it snugly. The tube should not be larger than an ordinary lead pencil, or about one- quarter of an inch in diameter. It should be long enough to project about one inch above the wound (Fig. 20) The abd(jininal dressings are then placed upon the wound around the tube and secured by 129 sterilized muslin bands which are pinned to broad adhesive straps fastened to the sides of the abdomen at some little distance from the wound. Over the top of the tube is slipped a piece of rubber dam (Fig, 26 a) about 12 inches square, the tube penetrating the cen- ter of the sheet rubber. The tube is then pumped out with a small glass syringe with a long rubber nozzle which will reach to its bottom (Fig. 27). After finally emptying the tube a long narrow strip of ster- ilized gauze is carried to the bottom of it with a straight metal sound, a small amount of the same gauze is left as a loose dressing over the end of the tube, over this is folded the rubber dam and fastened with a sterilized safety pin, and over all this is placed a liberal dressing of sterilized cotton and finally over this a snugly applied bandage of sterilized cotton. Figure 27. Now when it becomes necessary to exhaust the drain- age tube in an hour or two hours, it will not be neces- sary to disturb the wound dressing at all. The bandage is unfastened, the layers of cotton j^arted in the center and the rubber dam opened and sjDread out on the cotton, the capillary drain of gauze removed and the tube exhausted by means of the syringe, an- other strip of gauze inserted, the rubber dam refolded and pinned and the external dressings readjusted. I go into the detail of my method of caring for a drainage tube in order to justify myself for using it. As understood by the majority of good surgeons, it is really a dangerous means of draining. But a few weeks ago, in a discussion in a prominent society on. the subject of abdominal and pelvic surgery, I heeird 130 a surgeon of no mean repute condemn the glass drain and the suction pump, in unmeasured terms, when by his very language, he demonstrated his ignorance of the whole matter by saying that it was necessary to uncover the abdominal wound every time that the tube is exhausted. It is not necessary to uncover the wound at all to dress a glass drainage tube. It is not necessary to infect a glass drainage tube when uncov- ering it to exhaust it with the suction syringe, if the one doing the work is trained and competent. The nurse should be well trained. She should wash her hands to surgical cleanliness before loosening the bandage or removing the cotton over the end of the tube. She should rinse her hands in 1 to 1,000 bichlo- rid solution before unpinning the rubber dam; she should again rinse them in bichlorid before removing the capillary drain; she should take the glass syringe with its rubber nozzle out of a pitcher of 1 to 1,000 bichlorid solution, rinse it quickly in sterilized water, rapidly exhaust the tube, and eject the fluid into a small glass graduate which has just been removed from an antiseptic solution ; when the tube is dry she should take the steel sound out of a dish of bichlorid solu- tion, a strip of gauze out of a fresh supply from a sterilized package and insert it to the bottom of the drainage tube. She should again rinse her hands and then rajndly close the tube and replace the dressings. Such a procedure requires two minutes if done by an expert and intelligent nurse. I will agree with every- body that this kind of drainage can not be carried out by an ordinary nurse. But when well attended to it is the most satisfactory method of keeping dry the free abdominal cavity that we are as yet acquainted with. CAPILLARY DRAIN. Occasionally after extensive enucleation of diseased appendages we may be so situated that we have no experienced nurse to leave in charge of a glass drain- age tube; at the same time we must drain, and must drain in a manner that the after-care of the drain can 131 be attended to by one of little experience. In these cases combined capillary gauze and tubular drain, through the Douglas cul-de-sac, may be resorted to. A rubber tube one- quarter inch in diameter and about twelve inches long, and a quantity of sterilized iodo- form gauze in eight inch strips cut the strong way of the gauze without knots, are selected. After insuring thorough cleansing of the vagina the operator, guided by an assistant's j&nger in the vagina, penetrates the posterior cul-de-sac into the vault of the vagina with a pair of sharp pointed scissors. The scissor blades are then opened and between them from above down- ward, on a pair of forceps, is carried an end of the strip of gauze and the rubber tube. The assistant grasps these in the vagina and makes gentle traction on them. The operator then loosens his grasp and catches the abdominal end of the tube with a pair of catch forceps. The tube is then drawn through until from two to four inches of its upper end, according to the extent of drain required, is left in the abdom- inal cavity Enough of the gauze is drawn through to make a loose packing for the vagina. A small bunch of the gauze is left in the abdomen in the cul-de-sac, around the end of the rubber tube. It is closely packed so that it will remain in the position in which it is first placed. The abdomen is then closed in the usual manner. The vaginal end of the drain is ar- ranged by cutting the tube off at the vaginal outlet; and over the vulva and the end of the gauze is placed a liberal pad of loose sterilized dry strip gauze. Orders are given to change this outer gauze as often as it becomes moist. When at the end of twelve to twenty- four hours there is little drain, a portion of the gauze may be withdrawn from the vagina, and if the drain has been slight the tube may be removed at this time. In twenty-four hours longer, if the drain is still small or none at all, the drain may be completely removed. After the gauze has been removed, a liberal vaginal drain of gauze may be carried on the end of a forceps to the vault of the vagina. This may be removed in 132 twenty-four hours. After this nothing further is re- quired but an occasional vaginal antiseptic douche. If drainage is profuse after twenty-four to forty-eight hours the gauze drain should be withdrawn more slowly. Closing ahdominal Wound. — I favor any method which will coapt all the tissues of the abdominal wound in the exact relation and to the same extent that they were originally. This can be accomplished by including all the tissues, skin, fat, superficial and deep fascia, muscle, subperitoneal fascia, and peri- toneum in a row of silkworm gut sutures placed one- third of an inch apart. If I have some of my own specially prepared antiseptic catgut at hand, I fre- quently sew the peritoneal layer separately with a running thread of the gut and then include the remaining layers in the row of silkworm gut. This is especially desirable if one has a long wound in a hemorrhagic patient. It completely closes the abdom- inal cavity from any oozing from the abdominal incision. It also obviates the necessity of the silk- worm gut sutures entering the peritoneal cavity, thus removing the remote danger of adhesions of the abdominal viscera to the points of peritoneum pene- trated by the stitch, and danger of septic material gaining entrance to the peritoneal cavity along the route of the stitch, in case of external skin or mural sup- puration. I am careful to include all the tissues of my wound in order that the abdominal walls after incision will be as thick at the wound line as at any other position. If it is not, there will be a concavity at this point on the peritoneal surface which will act as a point of resistance, and which will favor abdom- inal x>ressure on the wound and from which ventral hernia is more liable to result. Before tying the silkworm gut sutures, I render the wound aseptic by washing thoroughly with 1 to 1,000 bichlorid solution (employing care that none of the jjoison enters the peritoneal cavity ) and finally rinsing the wound with sterilized water. After tying the 133 main sutures of the wound I always put in superficial stitches of fine silkworm gut wherever they are necessary in order to insure coaptation of the skin edges. Dressings. — Sterilized iodoform powder mixed with boric acid is dusted over the wound. Loose steri- lized strip gauze is placed over the wound, and sev- eral inches around it, and over this is placed a dozen thicknesses of sterilized sheet gauze. This is held in place by sterilized muslin straps which are pinned to broad bands of adhesive straps attached to the skin on the outer borders of the abdomen. This prevents the dressing from becoming displaced by any move- ments the patient may make, and it also supports the wound and takes the strain off the sutures. Over this is placed an abundance of sterilized cotton and over the cotton in turn is placed a snug abdominal bandage with a perineal T to keep it in place. AFTER-TREATMENT. For detail after-treatment I must refer the reader to Lecture VI. Dressing the Wound. — The wound is not disturbed until the fourth day unless there are symptoms indicating that it is not doing well, viz., pain, fever, etc. At the end of the fourth day the nurse uncovers the wound carefully, washes it thoroughly with alcohol, and 1 to 2,000 bichlorid solution equal parts, with sterilized cotton on the end of a dressing forceps. It is then dried carefully and redusted with sterilized iodoform and boracic acid. It is then re- covered with fresh sterile gauze. On the seventh day the same process is repeated and the stitches removed. After that it is washed off in the same manner every day until it is perfectly well. ANALYSIS OF CASES. I have removed the appendages for bleeding fibroids of the uterus in ^o cases. These cases have all recov- ered from the operation. The history, subsequent to lU the operation of a large per cent, of these cases, I have been unable to trace. Cases 26, 28, 47, 48, 55, 61, 64, or 14 per cent, con- tinued to menstruate indefinitely after the operation. Their symptoms were so severe in 26, 47, 48, 55, or 6 per cent, of the whole number that hysterectomy was afterward eiiiployed. In none of these cases was hysterectomy found necessary because of increase of the growth of the tumor. In the remaining cases, so far as I have been able to trace them, the tumors have reduced in size, hemorrhage has ceased and the patients have been materially benefited while in a small per cent, actual symptomatic cures were obtained. LECTURE IX, VAGINAL HYSTERECTOMY. HISTORICAL. Vaginal hysterectomy is closely associated in it early history with cancer of the uterus. Greig Smith says, that it is probable that incision of the uterus was practiced by the ancient Greeks, but it is certain that it was subsequently forgotten. Soranus, in his book of " Diseases of Women," who lived in Rome a century before Christ, describes the operation as a surgical procedure for prolapsus. The first authenticated description of vaginal hysterectomy subsequent to this was given by Berengarius, of Bologna, in 1507. In 1560 Andreas A Cruce performed vaginal hyste- rectomy. J. Schenck a Grafenberg 1617 (Senn) relates a number of cases in which the uterus was removed through the vagina in whole or in part by ignorant persons who had not the faintest idea as to the diff culty or of the extent and gravity of the operation. In 1792 Saumonier removed an inverted uterus below a ligature. Hildanus 1646, Wrisberg 1785, Bernhard 1821 reported cases of accidental or unintentional re- moval of uteri by the vagina by careless midwives and others. Intentional removal of the uterus by surgeons have been reported by Zwinger, Vieusse'n, Baxter, Faivre, Alexander, Hunter, Joseph Clark and Jack- son. (Senn.) The real history of vaginal hysterectomy begins when it was deliberately planned and executed for the relief of definite pathologic conditions. To J. M. 136 Langenbeck in 1813 belongs the credit of opening this page of history. He removed the uterus by enucleation, using neither clamps nor ligatures and his case recovered and lived many years. The post- mortem demonstrated to his incredulous critics the truth of his claim. Sauter, Jan. 28, 1822; Elias von Siebold, April 19, 1823; Holscher, Feb. 5, 1824; Elias voii Siebold, again July 25, 1825; Langenbeck, again Aug. 5, 1825; Recamier, July 26, 1829; Lan- genbeck, again Aug. 18, 1829; Roux, Sept. 20 and Sept. 25, 1830; Recamier, again Jan. 13, 1830; Blun- dell, Oct. 16, 1830; Siebold 1831, Delbach 1839 are the bold pioneers who followed the lead of Lan- genbeck in Europe. From 1839 to the revival of Czemy in 1878 there are no records of European cases. In America, however, a few cases were put on record during this long interval. Palmer Dudley reports that Dr. John M. Esselman, of Nashville, Tenn., in September, 1834, removed an inverted uterus by means of the ligature, his patient recover- ing. This same surgeon repeated the operation suc- cessfully in August, 1843, for an inverted uterus containing a fibroid. This is the first vaginal hysto- rectomy for fibroids of the uterus I find recorded. The first vaginal hysterectomy for cancer deliberately undertaken and successfully executed in this country was i^erformed by Dr. Paul F. Eve, of Augusta, Ga., April 16, 1850. (Am. Journal of Medical Science, 1858.) Dr. L. C. Lane, of San Francisco, operated for cancer Nov. 11, 1878, and at a later date in the same year on a second case for cancers. Both cases recovered. Lane executed this operation inde])endently of Czemy, who revived the operatic^n in Europe by I^erforming his first ojjeration April 12, 1878, or seven months earlier than Lane. From the revival of Czerny and Lane, with the dawn of clean surgery, the oi)eration of vaginal hyste- rectomy became a legitimate ojieration. In less than twenty yc^ars it has inade wonderful strides. It lias been performed thousands of times Vjy hundreds of 137 operators, and has, undoubtedly, been the means of adding many years to the sum total of human life. VAGINAL HYSTERECTOMY FOR FIBROIDS. It is argued that a patient suffers less real shock, on an average, when submitted to a vaginal hysterectomy than when operated upon by the abdominal route. The only rational explanation that can be forwarded to account for this fact is that the intestines and the peritoneum are not subjected to exjoosure to the air in the vaginal route, nor are they subjected to the hand- ling which they are liable to receive in the abdominal operations. While in our improved methods, the abdominal contents are exposed and handled to a small degree compared to former times, at the same time we can not help but recognize that there is less shock after a perfect vaginal hysterectomy than after an abdominal hysterectomy in cases of like severity. A vaginal hysterectomy avoids the abdominal scar, which so many patients dread as a brand of mutila- tion which must be carried through life after all abdominal operations. Many patients I find have this wholesome dread to such a degree that there seems to be no comparison in their minds between the two operations. An abdominal operation con- tains all the horrors of a most dreaded affair, while a vaginal operation with no sign of mutilation left, is contemplated like a normal labor with dread but resignation. An abdominal scar, it is true, will fre- quently become the seat of considerable irritation and rarely the seat of severe neuralgic jpains. There is always, too, the remote possibility of ventral hernias developing in an abdominal scar. It is also claiiiied. by not a few operators, that safer and more satisfac- tory drainage can be obtained, when it is required, through the vaginal route than by the abdominal. However, as soon as we undertake to do a vaginal hysterectomy on anything but the smallest kind of a fibroid, we are hampered by the narrow limits in which we have to do our work, and, therefore, if the 138 tumor is of considerable size, the extra time its proper removal from the vagina requires, off- sets what is gained by non-exposure of the abdominal viscera. So that the rational surgeon must discriminate here, as everywhere else in surgery, and select the opera- tion which best suits the individual case. If he has a small fibroid, or a large fibroid with relaxed liga- ments and a large, roomy vagina, he should select the lower route ; whereas, if he has a large fibroid high in the pelvis, or a small one with a narrow, contracted vagina and rigid tissues he should do a laparotomy and remove the tumor from above. Methods. — Vaginal hysterectomy for fibroids may be divided into two grand divisions: 1, removal of the uterus and its fibroid masses as a whole without division, or vaginal hysterectomy proper; 2, removal of the uterus and its accompanying fibroid develop- ment in piecemeal or morcellement. 1. VAGINAL HYSTERECTOMY PROPER. Indications. — Vaginal hysterectomy proper for fibroids must of necessity include only the smallest tumors, or at best fibroid uteri with long, slender sub- peritoneal projections. The operation is often the ideal method of treating small multii)le fibroids, which are so frequently the seat of severe uterine i)ain and excessive hemorrhage. Fibroids of considerable size may frequently be treated by vaginal hysterectomy, when the uterus is low in the pelvis and the vagina is large and the tissues loose. It is an easy matter to turn a complete vaginal hysterectomy for fibroids into a morcellement should any unlooked for enlargement manifest itself. TECHNIQUE OF VAGINAL HYSTERECTOMY PROPER. The patient should be prepared with the same care and manner that I have described in Lecture VI on prepanitory treatment for laparotomy. Special care should be maintained to rencler the vaginal tract and external genitalia aseptic. The patient should be 139 anesthetized with ether. She should be placed in the exaggerated lithotomy position with the limbs sup- ported by some mechanical device which will hold them firm and for any required length of time. Oth- erwise, they should be supported by strong skilled assistants on either side, who will also hold the vaginal retractors. Immediately before the operation begins a nurse or a third assistant should thoroughly scrub the external genitalia and the vagina with green soap. This should be thoroughly rinsed off, and the parts should be thoroughly washed with 95 per cent, alco- hol and finally rubbed with 1 to 1,000 bichlorid of mercury and then douched off with sterilized water. Moist sterilized towels are placed around the field of operation. The operator takes a seat at the foot of the table on a small stool. At his right are his instru- ments with the surgical nurse to do his bidding, At his left is the nurse who superintends the irrigator of sterilized water and handles the sponges. Operation. — Two small vaginal retractors, with short broad blades, are introduced and held by the assis- tants so as to retract the anterior and the posterior vaginal walls and expose the cervix uteri. The cervix is grasped by a light pair of vulsellum forceps with four teeth, the uterus rapidly dilated by first intro- ducing a small dilator and then a large strong one, until its interior can be reached and thoroughly explored with a sharp curette. The uterine cavity is thoroughly curetted and then rendered aseptic by wash- ing out with a solution of 1 to 100 bichlorid of mercury. It is then loosely filled with sterilized gauze. Through the cervix, by means of a curved needle, is passed a strong double handling string of braided silk, and this is tied over the os uteri in such a w^ay as to close the canal. The vulsellum forceps are now removed and the strong silk ligature is henceforth employed as a means of handling the uterus. The uterus is now drawn well down by making strong tractions and the cervix drawn back so as to expose the anterior utero- vaginal fold. With a curved scissors the mucous 140 membrane of the vagina at its attachment to the uterus anteriorly is penetrated and the incisions car- ried to the right and to the left following the utero- vaginal junction, until the incisions meet posteriorly and the uterus is completely severed from the vault of the vagina (Fig. 27). The assistant now grasps the Figure 27. handling string and makes downward and backward traction, while the operator with the index fingers of both hands carefully seimrates the bladder from the anterior surface of the uterus. If there are any firm bands connecting the two organs, they should be sev- ered with scissors near their uterine attachment, always 141 keeping the point of the scissors against the firm uterine tissue. As soon as the utero-vesical fold of the peritoneum is reached with the fingers the two fingers should be separated laterally, so as to detach the bladder from the anterior surface of the broad ligament, and also for the purpose of pushing the ureters, which pass under the broad ligaments near the cervix, well to the sides of the pelvis. The assistants now draw the cervix forward and the operator separates the uterus from its posterior attachments and the two fingers penetrate through the peritoneum into Douglas' cul-de-sac. The fingers are then separated laterally tearing the peritoneum in that direction. A large dry gauze sponge, with a string attached, is pushed through this opening and si^read out above the uterus. The broad ligaments and the appendages are then rapidly examined. The peritoneum in front of the uterus between it and the bladder is now torn through and the broad ligaments are the only attachments left between the uterus and the patient. If the uterus is not too large and the broad ligaments are loose and the vagina large, one pair of strong forceps will secure each broad ligament. The uterus is drawn well down and the operator slips his index finger of the left hand behind the left broad ligament and crowds the appendages toward the uterus until he can hook the finger over the ligament outside of the appendages. With the uterus held well down and steadied by one of the assistants, the other assistant holding the bladder well out of reach by a long narrow bladed retractor, the operator with his right hand slides a strong pair of Byford's clamp forceps (Fig. 28) over the broad ligament, the poste- rior blade following the lead of the index finger, which is still holding the ligament, until they include its whole width, and project half an inch beyond its upper edge when they are closed and locked. The jaws of the forceps should be examined carefully to see that they include all the tissues necessary, and that it compresses all portions sufficiently. The locks 142 of the forceps should be securely tied. With the index finger guiding the scissors, the clamped liga- ment is now severed close to the uterus. If the uterus is not too large and the right broad ligament is long the organ can be delivered as the next step and when delivered the right broad ligament may be clamped with ease outside of the vulva. If this is possible the clamp should be applied outside of the appendages and the uterus cut away. Frequently, however, the uterus can not be delivered until the other clamp is ai)plied and the ligaments severed. Under such circumstances the forceps should be care- fully aj)plied exactly like the first one and the liga- ments divided with the scissors from below upward Figure 28. while the assistant makes slight traction on the uterus until the organ is free, when it is delivered. The broad ligament forceps are carefully examined now, to be sure that each is doing all the work required of it, viz., including the whole ligament in its .grasp and firmly comjjressing every portion sufficiently tight to maintain hemostasis. Should any portion need rein- forcing, a small pair of straight hemostatic forcejjs may be ajjplied to the projecting free end of the sev- ered tissue. Occasionally it is not practicable nor safe to include the whole broad ligament in one pair of forceps because of its width and bulk, while again it may be difficult to j)lace the forceps on the whole 143 ligament at once, because of a too narrow vagina or a highly situated uterus with short ligaments. Here the bulky base of each broad ligament should be clamped first, with short stout catch forceps and the ligaments severed up to within a short distance of the forceps' bite. The uterus then can be drawn down and the remaining portion of the broad ligaments can be secured in one pair of forceps on each side. The last forceps are placed on the uterine side of the first pair. All the forceps are now held by the assistants to their respective sides of the vagina with their handles separated in such a manner as to act as lateral retractors. The sponge is removed from the pelvis and the toilet of the peritoneal cavity is made by drying it with sponges on holders. The posterior retractor is now inserted and the operator seeks the edge of the peritoneum which covers the bladder, grasps it with a catch forceps and draws it down and with a running stitch of antiseptic catgut attaches it to the upper end of the anterior vaginal wall. An anterior retractor is now inserted and the edge of the peritoneum covering the rectum is attached to the upjper end of tliQ XDOsterior vaginal wall in the same manner. This insures hemostasis of the anterior and posterior vaginal edges, and covers an otherwise uncovered gap of connective tissue space. Drainage. — The forceps are widely sej^arated, two narrow retractors hold open the vagina anteriorly and posteriorly, a square piece of sterilized iodoform gauze two feet wide is placed with its center over the vulva, and with a large pair of dressing forceps its folded center is carried well into the vagina beyond the ends of the forceps, so as to form a bag. It is then loosely packed with strips of sterilized iodoform gauze and the edges of the filled bag are left projecting several inches from the vulva. It is folded over the vulva. The handles of the clamp forceps are wrapped in gauze. A liberal supply of absorbent cotton is placed over and around the forceps and over the perineum and vulva, and all held in place by three small perin- 144 eal bandages, one passing between the handles of the forceps and the other two outside of the forceps handles. VAGINAL HYSTERECTOMY BY MORCELLEMENT. Indicdfions. — Vaginal hysterectomy by morcelle- ment may be done for fibroids of considerable size, the limit of maximum size on which the operation may be safely undertaken depending on the skill and expe- rience of the particular operator. The writer does not favor the ojDeration where the uterus is too large to deliver easily after bisecting, preferring to undertake such cases by the abdominal route. The operation is now performed every day, however, by an increasing number of skillful men on fibroids of every size, even on tumors reaching well above the umbilicus. Polk, a firm believer in morcellement for fibroids, lays down the following indications: 1. Whenever the mass is largely within the pelvis, especially if it is fixed therein by adhesions. 2. Whenever the mass is soft and, therefore, compressable as in myoma and fibrocystoma. 3. In all other cases where we have a patient in good condition ^ose pelvis is shallow, where the vaginal canal is roomy, and in whom the evidence of a pyosalpinx above the j^elvis brim are absent. Pean, Segmond, Richelot, Jacobs, Henrotin and others do not make suppurating appendages a contraindication to this method of operating. TECHNIQUE. Crises with Uterus only Double its Natural Size. — In these cases the technique is very similar to that for simple vaginal hysterectomy, with the exception that the uterus is bisected with an antero- j)osterior incision. Step 1: The vagina is severed close to the cervix, as in ordinary vaginal hysterectomy, and the uterus denuded until the posterior and anterior cul-de-sacs are opened. Step 2 : Grasp the anterior lip of the cervix on either side with strong bullet forceps or two well embedded 145 handling strings, and making strong traction split the anterior wall of the uterus with strong scissors with the posterior blade guided by the uterine canal (Fig. 29). When the scissors have reached the limit of exposure of the uterus the edge of the split uterus at the highest point of the incision should be grasped by the bullet forcei^s, and with this new grasp the uterus should be drawTi down still farther and the Figure 29. splitting process continued. When the uterus is usually movable or the broad ligaments unusually long, sometimes at this point the partially split uterus is completely anteverted and the fundus is delivered. As a rule, however, whenever it is necessary to split the uterus at all in order to remove it, the bisecting must be carried to completion. 146 Step 3: When the bisected uterus is well drawn down, the increased movability of the organ in conse- quence of being in two pieces enables one to clamp the broad ligaments with one, or at most two forceps, and the respective halves are removed. After one side has been cut away it is an easy matter to clamp and remove the opposite half. Step 4: Finish operation and apply drainage as in simple vaginal hysterectomy. Variations of Procedure. — If it is convenient it is often better to attempt to clamp the broad liga- ments immediately after opening the two cul-de-sacs, in order to save the patient as much blood as possible. When it is not possible to clamp the whole broad lig- ament, the base of the ligaments with the uterine arte- ries may be secured. As a preliminary every precau- tion should be observed to render the cavity of the uterus aseptic. Cases icith Uterus More than Double Its Normal Size. — In these cases the uterus must be removed by piecemeal. In order to accomplish this so as not to make a horrible failure, a thoroughly systematic course must be observed by one skilled in the details of pelvic surgery and surgical emergencies. No two cases are alike. Consequently no two operations are ever identical. Step 1: Circular incisions around the cervix, after first grasping the anterior and the posterior lip of the cervix with strong forceps. The uterus is denuded anteriorly and posteriorly and the posterior cul-de-sac is opened. An attemj^t is then made to enter the anterior cul-de-sac. Step 2: Clamp forceps are now placed on the base of each broad ligament high enough to include the uterine artery and its branches, and the ligaments are cut nearly as high as the point of the clamp. Step 3: The cervix is split into halves by a lateral incision on the line of the uterine canal with strong scissors or a knife (Fig. 30). Step 4: With the anterior lip well drawn down and 147 firmly held, the posterior lip is drawn well down and amputated. The remaining stump of the posterior half of the uterus is firmly grasped in forceps, keep- ing the uterus well down in the field of operation. Step 5 : If the uterus is not too large at this point a single clamp forceps may be placed on the remaining portion of the broad ligament. Figure 30. Step 6: With hemostasis well secured, from this point on the splitting of the uterus is continued and morcellation is proceeded with by amputation of first one-half or a portion of a half and then the other, sever- ing the broad ligaments by degrees until by piecemeal 148 the whole uterus is removed. Care should be main- tained to have a secure hold of the uterus with forceps at some point besides the point of amputation at all times, in order that it may not slip out of the field of operation. As soon as the uterine mass has been reduced suflBciently so that it may be delivered it should be removed. Care must be exerted to secure all large subperitoneal masses which from their situa- tion might by carelessness be accidently separated from the tumor and escape beyond the reach of the finger or forcej^s. As the morcellement progresses a finger in the x^osterior cul-de-sac from time to time learns facts of value to the operator. Bemarks. — The care of the forceps and the care of the vaginal and jDeritoneal edges, after this modified operation, is identical to that after the simple opera- tion. The toilet of the operation field and the drain- age is the same. If adhesions exist they must be care- fully separated. If the anterior cul-de-sac is elevated so that it can not be entered before amputation is commenced, amputation should be proceeded with and the uterus gradually drawn down until the cul-de-sao can be opened. Accidents to he avoided. — Wounding of the bladder or intestines and clamping one or both carelessly are accidents which must be carefully guarded against in vaginal hysterectomy of any kind. Severing of important blood vessels before they are securely clamped is another annoying accident, because of the tendency of the unsecured blood vessels to retract into the loose connective tissue of the broad ligament, where they will continue to bleed out of reach of hemostatic forceps. To avoid this accident great car© should be observed to securely clamp all tissues before severing, and if there is the slightest doubt about the security of any portion of the divided ligament after it has been cut, a second clamp should reinforce the first. To avoid clamping the ureters the forceps should not be applied to the base of the broad ligament until the bladder is thoroughly separated from its anterior 149 surface, until the finger can sweep between it and the broad ligament to the sides of the pelvis. This insures the pushing of the ureters out of the reach of the forceps. This same maneuver insures the integrity of the bladder also. If the bladder is found so adherent at any portion that it is not readily separated with the finger, scissors should be employed to dissect it from the face of the uterus or tumor, great care being observed to avoid wounding the bladder with the scissors by keeping the point of that instrument against the uterus. By following the imperative rule of separating the bladder early and keeping it out of the field of oj)eration by the use of an anterior retractor, it will never be wounded. To avoid wounding the rectum the same care should be observed in entering the posterior cul-de-sac as is exerted in opening the anterior one. If one carelessly opens this pouch, it is an easy matter to strip the peritoneal covering of the bowel posterior to the cul- de-sac and miss entering the peritoneal cavity entirely ; while by ignorantly pursuing this false track the rec- tum may be penetrated. To avoid this embarrassing predicament stick to the uterus. If one does strip off a portion of the uterine peritoneum it will do no harm and the rectum is safe. USE OF LIGATURES FOR VAGINAL HYSTERECTOMY. By some operators ligatures are emjDloyed for secur- ing hemostasis instead of clamps. In simple, uncom- plicated cases ligatures may be employed with ease. In morcellement, where high and excessive manipula- tion is required the ligatures are impracticable be- cause of the. difficulty of applying them, and because of the difficulty of preventing them from becoming loosened by the subsequent manipulation of the parts. When ligatures are employed they prolong the con- valescence if they are left long and allowed to ulcerate away. The time required for the accomplishment of that act is from twelve to forty days. During all this time it requires great diligence on the part of the 150 attendant to prevent infecting of the ligatures; in fact, it is seldom prevented. An offensive vaginal dis- charge bears evidence of the fact, until the ligatures are finally discharged. If ligatures are employed and cut short, with the idea of burying them, it fre- quently happens that they become infected, even when the greatest care is observed to preserv^e cleanli- ness. The reason for this is the necessity for drain- age in almost all of these cases. The method of drainage makes the wound practically an open one. Hence the danger of some portion of the otherwise buried ligatures becoming infected. Once infected long months of pus discharge from vaginal fistula is the sequel. This is all avoided when hemostasis is secured by strong forceps, because the means of hemos- tasis (the forceps) are removed in forty-eight hours, and nothing is left of a foreign nature which may be- come infected. AFTER-TREATMENT OF VAGINAL HYSTERECTOMY WITH CLAMPS. Shock is treated on the lines laid down in Lecture VI. I must, also, refer the reader to that Lecture for the detail treatment of the bowels and care of the patient as regards drink, diet, etc. The bladder is emptied every eight hours with a catheter until the forceps and the first drainage is removed. The catheter should be employed oftener if it is neces- sary. The nurse employs an aseptic glass catheter with a small nozzle which will run the urine off into a bottle. The urethra is carefully exposed before the catheter is introduced and thoroughly wiped off with a saturated solution of boracic acid. Forceps. — The locks of the forceps are carefully tied at the time they are put on to avoid accidental unclasping of their blades. The handles are kept covered with sterilized gauze. If it gets soiled at any time it is changed. At the end of twenty-four hours all but the principal forceps are removed. The string securing the lock is cut, the lock unfastened carefully, 151 the blades opened enough to loosen their grasp on the tissues and then they are carefully removed. At the end of forty-eight hours the main forceps are removed in the same manner. If the tissues in any particular case showed unusual tendencies to bleed at the time of the operation I allow the forceps to remain twenty- four hours longer. When the large forceps are re- moved they should be opened widely before an attempt is made to withdraw them, and then they should be brought out with a backward motion in order to avoid catching the tissues with the projection on the pos- terior blade. Di^essing. — If the external portion of the drain be- comes soiled with accidental discharges of urine or excessive drain fluid it should be removed and replaced with a new^ external pad of loose sterilized gauze as often as is necessary. Twelve hours after the last forceps are removed about one-third of the external gauze drain should be removed and a fresh pad of gauze placed over the vulva. In twenty- four hours another third should be extracted, and in twenty-four hours more, or sixty hours after the last forceps are re- moved, all of the balance should be taken out. When the last gauze is removed an external irrigation should be employed of 1 to 5,000 bichlorid solution followed by a plain water irrigation. A small sterilized iodo- form drain should now be carried carefully about three inches into the vagina on a strong pair of dressing forceps, and the end of the drain allowed to protrude from the vagina. Over this is placed an antiseptic absorbent pad. In twenty-four hours this drain is removed and then eighty-four hours after the last for- ceps are removed, and the peritoneum has had ample time to close, the first vaginal douche is given. Douches. — This douche must be given with extreme care by a nurse who understands all the responsibility she is entrusted with. The douche point must be made of glass, bulbous, with openings directed only at right angles to it. The patient should be placed on her back at the edge of a bed with feet supported 152 on two chairs. A Kelly pad should be under her buttocks. The reservoir containing sterilized water of a temperature of 105 should be placed but eighteen inches above the patient's hips, in order to have but slight iDressure. The nurse after thoroughly preparing her hands, inserts two fingers into the vagina about two and one-half inches, and between the lingers ex- tending to within one-half inch of their extremities is inserted the douche point. The water is turned on with every x^recaution employed to secure immediate and free return current. The douche is repeated in this way, the nurse introducing the fingers and douche point a little further each time until the vault of the vagina is reached, every twelve hours until the sixth day from the removal of the forceps, when 1 to 5,000 bi- chlorid of mercury solution may be substituted for the I)lain douche, always following the bichlorid douche by a plain one. It must be obvious why I insist on the great care in employing this douche. The peritoneal cavity is expected to close in a few hours after the gauze is removed. Frequently, there is no doubt, it is closed off a few hours after the operation is finished. Notwithstanding this tendency to early closure of the peritoneal cavity, carelessness in employing the first few douches, if free return stream is not provided and great pressure employed by placing the reservoir too high, might result in breaking up the union of the tissues and fill the abdominal cavity with the fluids and debris of the vaginal tract. After each douche the vulva should be covered with an antiseptic pad. After each urination or movement of the bowels the external parts should be douched otf with sterilized w.iter and the antiseptic dressing renewed. (jfettuifj Up. — Patients manifest a desire to get up earlier aft(^r vaginal hysterectcjmy than after abdominal operations. There is less prolonged reaction in the way of nervous exhaustion as there is less immediate shock with the vaginal o])eratiedicle allowed to contract into abdominal incision. 2. Iiitra-peritoneal Method. — This, as practiced by Schroeder, consisted primarily in constricting the jjedicle with the Kleeberg rubber band, removing the tumor, paring down the stumi), taking from its center a wedge-shaped piece of the bulky tissue, cauterizing the canal, closing the stump by strongly sewing 157 together the edges of the wedge-shaped incision and finally sewing over all the jjeritoneal edges. The stitching of the stump was intended to bo secure enough so that all subsequent oozing was made impos- sible after the final removal of the rubber ligature. The iDedicle was then dropped, as is the pedicle after ordinary ovariotomy, and the abdomen closed. This method was modified by Olshausen, Charles T. Parkes, Zweife], Hofmeier and others. (a) Olshausen modified by securing the pedicle with a rubber ligature, and sinking the whole by sewing over it the f)eritoneum. (b) Charles T. Parkes modified it by ligating firmly with strong silk and cauterizing the tissues of the pedicle to firm bone-like condition w4th the actual cautery over a temporary clamp. (c) Zweifel tied the pedicle firmly with a strong multiple ligature of silk, securing it in this manner in several parts. (d) Marcy of Boston, 1881, secured an intra- abdominal stump by sewing from the outer edge of one broad ligament to the other with thirteen cobbler's stitches; including in the process ovarian arteries, broad ligaments, uterine arteries and the stump of the uterus formed by the cervix uteri. (e) Hofmeier carefully ligated the pedicle in its cir- cumference without closing the cervical canal, and closed its abdominal end by covering with peritoneum. Drainage could take place into the vagina through the patulous canal. (/) Goffe and Albert independently employed treat- ment similar to Hofmeier's, with the addition of applying a capillary drain through the open cervix into the vagina. 3. Complete Removal, Eastmaifs methods. (a) In 1888 Dr. Mary A. D. Jones removed the entire uterus, including the cervix, by employing long hemostatic forceps for the lower portion of the broad ligament, and severing the cervix from the vagina. (6) Joseph Eastman's method, 1889: The broad 158 ligaments are tied off, including the appendages, the vagina opened posteriorly by elevating it by means of a special staff constructed for the purpose, which is held by an assistant, the vaginal edges are ligated with long ligatures which afterward serve to invert the edges into the vagina, and the cervix and stump are progressively cut away. The iDeritoneum is sewed over the inverted vaginal edges^ the abdominal wound is closed, and the vagina packed with gauze. The mass of the tumor, if cumbersome, may be cut away, pre- vious to opening the vagina, by putting on a tempo- rary rubber ligature. (c) Eastman in 1884 enucleated the stump without first tying the uterine arteries by peeling the pedicle portion of the uterus with a serrated gouge, keeping inside of the uterine arteries in their course up the side of the uterus. 4. Vcujinal Fixation, Byford's Method, — The broad ligaments are tied with silk and severed. The cervix is secured with provisional rubber ligature, the tumor €ut away, the pedicle firmly tied with multiple silk ligatures, left long, the stump trimmed and closed with long silk ligatures, an opening made into the vagina in front of the cervix, the ligatures securing the pedicle carried through it by traction on them, the stump inverted into the vagina, the peritoneum over the inverted cervix closed by stitching the bladder peritoneum to that covering the pedicle, closure of the abdominal wound, and finally j)lacing a special hemostatic clamp on the inverted pedicle in the vagina. Meinert, independently of Byford, suggested pulling the pedicle into the vagina through Douglas's cul-de- sac, but is not known to have accomplished it. Polk, of New York, has removed the entire cervix, stitching the vaginal stump to the abdominal wall. Thus briefly do we get an outline history of the develoi)ment of the technique of this important oper- ation. Erom the beginning the struggle was in the direction of accomplishing complete hemostasis of 159 the pedicle without the necessity of invariably fixing it in the abdominal wall. It was soon demonstrated that no XDedicle comprised of cervical or uterine tissue could be made bloodless by any amount of ligating with non-elastic ligatures which could not from time io time be tightened as the tissues shrunk. Hence with silk, steel or clamj) hemostasis it was necessary to fix the pedicle externally in order that they might be tightened in case of necessity. Elastic ligatures, while they accomplished perfect hemostasis, experi- ence soon demonstrated were not safe ligatures to bury, because they frequently gave rise to suppuration when the strangulated pedicle was dropped. At last it .seemed inevitable that external fixation of the pedicle was to be the only safe method of accomplishing abdominal hysterectomy. The displacement of the tissues necessary for abdominal fixation and its dis- tressing sequelae — bladder pressure, painful cicatrix, dragging pain, hernise, depressed cicatrix, etc., made surgeons slow to accept that means as final, while at the same time there seemed no other alternative. The Taginal fixation of Byford's which came in late in the race, solved many of the difficulties, and if something better had not speedily followed, it would have become the ideal method of pedicle fixation. But when the struggle was at its height the w^hole problem was sud- denly solved by the ap]3lication of a simple little prin- ciple described by Stimson in 1889 and i^racticed by ■others and redescribed and emphasized by Baer, of Philadelphia, in 1892. The principle consists in obtaining hemostasis of the uterine stum^D by ligating its blood supply outside of the uterine tissue before it reaches its substance; or, in other words, by ligating the uterine arteries at either side of the cervix. East- man had practically accomplished the same thing in his old operation of complete removal of the uterus the same year Stimson announced it, but none of us recognized the princij^le involved, nor did he announce with sufficient emphasis why he succeeded. So Stim- son and Baer get the credit of promulgating and 160 establishing a great but simple principle, and the uterus is removed every day now, j^artially or wholly, and the pedicle di'opx^ed with perfect impunity. 5. Ligation of Arteries at Side of the Uterine Tissue with Intra-abdominal Stuwp: Stiwson-Baer Mctliod. — This method is accomplished by ligating the ovarian arteries with or without the broad liga- ment, severing the broad ligaments after placing hem- ostatic clamps on the uterine side down to the uterine arteries, ligation of the uterine arteries, severing the uterus at the cervix, cauterizing the cervical canal, trimming the cervix, closing the stump with catgut or silk, burying the pedicle with peritoneum, closing the broad ligaments with a running stitch of catgut, and closing the abdominal wall. Senn modifies this operation by stri]3ping the tumor of its peritoneum in front and behind for three inches, severing the tumor at its bottom so as to leave the peritoneum like a cufp and then fixing this cuff open to the lower angle of the abdominal wall, draining it with iodoform gauze until all danger of hemorrhage has ceased, when the gauze is removed and the cuff closed by closing the abdominal wound by tying sutures inserted at the time of the operation. Stim- son-Baer principle when thoroughly carried out makes Professor Senn's precautions superfluous. INDICATIONS FOR ABDOMINAL HYSTERECTOMY FOR UTERINE FIBROIDS. Successful abdominal hysterectomy is the only absolutely sure cure for large fibroids of the uterus. Ergot, electricity, ligation of the blood supply will cure a certain percentage, but hysterectomy removes at once every vestige of the tumor and with it the uterus on which it j^ropagates. The operation of abdominal hysterectomy, in its I)resent condition of perfection, in the hands of expe- rienced operators should be the operation of selection in all fibroids which can not be removed by vaginal hysterectomy when the patient is in a physical condi- 161 tion which will not jeopardize her immediate recovery from the operation. Multiple intramural fibroids of every kind which are producing distressing symptoms should be sub- mitted to hysterectomy because there is no absolute cure for them by any other means. SuhjyeritoneaJ fibroids when from multiple develop- ments can only be removed by abdominal hysterec- tomy; no other treatment will reach them. Interstitial fibroids of large size, of hemorrhagic nature, if the patients are in a fair physical condition, should always be treated by abdominal hysterectomy. Cystic fibroids can only be cured by hysterectomy. Any form of treatment less radical only aggravates these cases. Suj)purating fibroids imperatively demand hys- terectomy. Fibroids complicated with pelvic suppurations, pyosalx^inx, supi^urating ovaries or appendicitis, should be removed at the same time that the pelvis is cleaned out. Large fibroids complicated with pregnancy where there is the slightest doubt of a successful normal ending of the condition of pregnancy, demand abdom- inal hysterectomy. ABDOMINAL HYSTERECTOMY — TECHNIQUE. Uncomplicated Case. — The writer adopts the Stim- son-Baer operation for uncomplicated hysterectomies for any cause. The abdomen is opened with a liberal incision which will allow of easy delivery of the tumor. The lower end of the incision is carried well down to within an inch of the symphysis pubis. If the bladder is unusually high the incision at the lower end need not include the peritoneum. The tumor should next be delivered by lifting it out with the hand or a strong joair of vulsellum forceps fixed in the fundus of the uterus or top of the tumor. It is very necessary that the tumor be delivered at this point in order to continue the work of removal intel- 162 ligently. As soon as the tumor is outside of the abdomen the general peritoneal cavity should be shut off with liberal packs of diy sterilized gauze. If the intestines are inclined to protrude the abdominal incision may be closed above the pelvis with a tem- porary silk suture. The broad ligaments are next clamped with a strong j)air of long jawed hemostatic forceps far enough away from the uterus so that another forceps of the same character may be placed between it and the uterus, and low enough to include all the upper portion of the broad ligament with the ovarian arteries. The broad ligaments on either side are next severed between the forceps to the lower limit of their bite. This frees the uterus well down to the cervix and the region of the uterine arteries. The peritoneum on the anterior surface of the uterus is severed at the utero-vesical fold transversely, the ends of the incision ending at the two provisional forceps placed on the uterine end of the severed broad ligament. The cervix is then stripped of its peritoneum anteriorly, care being exercised to sepa- rate the bladder from it, thoroughly. After the uterus is well denuded of its peritoneum belov/ the point marked off by the knife, and the bladder is well separated a gauze sponge of small size may be placed temporarily on the denuded surface. It is well at this point, too, to peel off' a small flap of peritoneum from the posterior surface of the lower jjortion of the body and cervix, beginning an inch above the i)oint at which the stump will be made, and denuding to a point just below it. The uterus is now drawn well to one side, retractors placed on the opposite side and the uterine artery is secured by placing around it a strong silk or antiseptic catgut ligature. The artery is securely tied and the ligature left long. A pair of artery forceps is placed on the tissue secured by the ligature between it and the cervix, and the tissue sev- ered between the forceps and the uterus. The oppo- site side is treated in the same manner. The uterus ifl now removed by severing it at its neck. The inci- 163 sion is begun about an inch above the vaginal attach- ment anteriorly and posteriorly and carried toward the uterine canal in such a way as to leave the uterine stump, a hollow wedge with the apex at the cervical canal, and the sides of the wedge the anterior and posterior surfaces of the stump, which when approx- imated, form flaps which completely shut off the cervical canal and the cavity of the pedicle from the abdominal cavity. The uterus can be severed from the cervix best with a knife. As soon as the flaps Figure 28. are begun posteriorly and anteriorly the stump should be steadied and controlled by securing these flaps in strong lock forceps. (Fig. 28.) As the uterus is sev- ered great care should be exerted not to infect the abdominal cavity with any septic matter which may be in the uterine canal, and the cervical canal must be immediately cauterized or otherwise rendered sterile. The stump is now closed by uniting the two flaps with inversion sutures of antiseptic catgut. The simplest 164 and most satisfactory method of suturing for this pur- pose in my opinion is the one employed by Prof. A. H. Ferguson, Fig. 29. The stitch is an interrupted one as shown in the drawing, and completely closes the flaps without i^enetratmg their cut surfaces. Prof. Ferguson uses the stitch in bowel surgery to take the place of the Lembert suture. When the pedicle is closed it is dropped. At this point the upper portion of the broad liga- Fjoure 29. Method of suturing the pedicle in hysterectomy; a, pedicle unclosed; b, pedicle and method of introducinf? inversion stitch; c, the comx)leted pedicle. ment upon which the provisional hemostatic forceps were jjlaced must be cared ior. It contains the ova- rian artery as it passes along the broad ligament par- allel to the infundiV)ulo-pelvic ligament which should be securely tied. Next if the pedicle of the broad liga- ment is long enough so that it can be easily included in the ligature left long after ligating the uterine artery 165 without undue tension, it should be so included, secur- ing the ligature from slipping by taking a turn around thfe infundibulo-pelvic ligament. When the ligament is in place ready to be tied the forceps should be re- moved from it and the ligature firmly tied, with a treble knot, and forceps attached to the pedicle out- side of the ligature. The opposite side is treated in the same manner. Everything is now finished about the pedicle except closing the peritoneum over the stump. This is accomiplished by stitching together with a running suture of antiseptic catgut the two edges of the peri- toneum which was stripped off the anterior and pos- terior surfaces of the uterus before amputating the uterus. When this is done the pelvic peritoneum is perfectly closed, and as soon as the toilet of the cavity is completed, the abominal wound should be sutured, the dressings applied and the patient put to bed. Remarks. — The Trendelenburg position may usu- ally be used with advantage immediately after the uterus is amputated in order to ex^Dose the bottom of the pelvis. Some operators place their patients in this position from the beginning of the operation. Drain- age is not necessary after a normal case. COMPLICATED CASES, Unfortunately in the surgery of fibroid tumors uncomplicated cases are not the rule. The most com- mon anomalies are the following: 1, pedunculated tumors; 2, tumors developed into the broad ligament; 3, interstitial tumors involving the cervix; 4, tumors complicated with diseased appendages; 5, sui^purating fibroids; 6, tumors complicated with pregnancy; 7, extra-peritoneal fibroids. 1. Pedunculated Tu)nors. — Tumors of varying sizes with small pedicles are occasionally found grow- ing from some portion of the uterus. If they repre- sent a distinct tumor and the uterus is not involved with separate or other centers of fibroid development, and the appendages are not involved, the operator 166 sliould seek to remove the tumor without interfering with the uterus proper. In order to accomplish the removal of these pedunculated masses, and secure a pedicle which may be safely dropped a definite line of procedure should be followed. If the tumor is only partially pedunculated so that a portion of its bulk is buried in the uterus necessitating enucleation, I pre- fer to remove the uterus, as I consider that the only absolutely safe procedure under the circumstances. If the tumor, however, is pedunculated, so that a pedicle of peritoneum, connective tissue, and the blood vessels feeding the tumor, without tumor tissue or uterine tis- sue, can be secured after its removal, I do not hesitate to ligate and drop the pedicle any more than I would hesitate to drop the pedicle of an ovarian cyst. Method: The tumor is delivered. A pair of strong hemostatic forceps is clamj)ed on the pedicle between the tumor and uterus, unless the tumor encroaches upon the pedicle too much to make a clamp effective after the growth has been enucleated, when instead of a clamp a provisional rubber ligature should be used. The tumor should now be cut away. If the pedicle is long and not involved by the tumor it should be severed close to the tumor, thus leaving abund- ance of tissue external to the clamp. If the pedicle is short and encroached ui)on by the tumor, the inci- sion should extend around the base of the tumor at a distance of at least two inches from the provisional rubber ligature, involving the peritoneal coat and con- nective tissue capsule of the tumor (the pedicle edges of the incision being caught on three sides by hemo- static forceps to control the stump and prevent sliiJ- ping of the ligature), and the tumor is enucleated, leaving a pedicle of connective tissue, blood vessels and peritoneum. The pedicle is treated in both cases alike. If blood vessels of considerable size are found in the free end they should be ligated separately close down to the provisional clamj) or ligfiture. Then a strong anti- septic catgut or silk ligature should transfix the pedi- 167 cle near its edges, and, after tying the first knot the provisional clamp or ligature should be removed and the ligature securely tied, so as to secure every portion of the pedicle. If care has been observed to eliminate all uterine or tumor tissue from the pedicle it will be as secure now as an ordinary pedicle of an ovarian cyst. The pedicle should be trimmed down to within an inch of the final ligature. The writer has removed two pedunculated fibroids of large size in this manner, one of ten pounds and another of eight pounds, in which pregnancy existed, the women both going on to term afterward and giving birth to their children without complications. One of these conceived afterward. Another case of this kind in which a tumor of large size was removed, afterward conceived and gave birth without complications to a living child. 2. Tumor developed into the broad Ligaments. — It is not a rare complication to find these tumors of the uterus develoxDed in the folds of the broad ligament to such an extent that the ligament is si^read out over the growth and its folds tense. Frequently it will be impossible to deliver the uterus until the por- tion has been enucleated from the broad ligament. The line of procedure here is: First, enucleate the tumor from the broad ligament, and second, deliver the uterus as in uncomplicated cases and complete the toilet in the same manner. First step: Tie if possible the ovarian artery near the outer edge of the tumor near the pelvic walls. If more convenient a provisional forcep may be used to secure the vessel. Second step: Split the tense peritoneum which represents the broad ligament, the folds of which have been eradicated by the burying tumor, by draw- ing a scalpel over it at its most prominent i3oint in a direction from the uterus to the side of the pelvis. Then with the fingers or some blunt instrument the tumor is gradually peeled from its subperitoneal bed, constant traction being exerted on it until the uterus and tumor are delivered. 168 Third step; Completion of the operation as in a normal case. 3. Interstitial Tumors involving the Cervix. — When the fibroid has developed low in the substance of the uteiiis so as to occuj)y the cervix, some management is required in order to secure a proper pedicle. Two methods may be pursued; first, complete enucleation of the fibroid tissue from the cervix, and second, com- plete removal of the cervix. When it is possible, I prefer to enucleate the tumor from the cervix in order to preserve that por- tion of the uterus for a pedicle and a key to the abdominal floor. The first part of the operation is conducted as in a normal case or if any portion of the tumor is subperi- toneal as in the last method described. When the region of the large cervix is reached, a blunt instru- ment should be employed to comj^letely enucleate it from all surrounding tissue, the bladder in front and all lateral tissue in order to insure perfect security of the ureters. This can only be done by keeping the point of the enucleating instrument well against the uterine tissue. If there is difficulty in securing the uterine arteries definitely, because of the necessary distortion of the tissues, two strong Tait pedicle-pins should transfix the cervix, at right angles to each other, their ends being supported by the abdominal walls, and beneath these a provisional rubber ligature should be placed. The tumor is then cut away, down to the i^edicle-pins, and the uterine arteries are sought and tied. After insuring hemostasis, the elastic lig- ature is removed and the fibroid tissue of the cervix carefully j^eeled out of its ca})sule. From this point the case is treated as a normal hysterectomy. Removal of the cervix: Occasionally it may seem l)est to remove the entire cervix when it is the seat of the fibroid invasion. The same course should be pursued here as when the cervix is to be retained. The uterus may or may not be severed above a provi- sional elastic ligature, before ligating the uterine 169 arteries. When the cervix has been thoroughly stripped and the vagina rendered aseptic, the vagina should be opened at the anterior or i^osterior cul-de- sac close to the cervix, and one blade of a curved pair of scissors slipped through into the vagina, and the cervix completely severed from its vaginal attachment by following the circumference of the cervix with the scissors. A guide in the vagina in the form of a staff may be employed in making the first vaginal incision. If there are any small bleeding points on the vaginal edges they should be tied with catgut or twisted with hemostatic forceps. The vagina should be loosely packed with sterilized iodoform gauze from above so as to just reach to the upper end of the severed vagina. The tissues in the bottom of the pelvis naturally fall together. ^With abundant drain in the vagina I simply allow the upper end of the vagina and the other severed tissues to fall together naturally, con- tenting myself to close the peritoneum alone with a running antiseptic catgut suture, exactly as when the cervix is allowed to remain. 4. Tumors compliccdedwiih diseased Aiypendacjcs. — Diseased aiDpendages are a frequent accomj)animent of fibroids of the uterus. When fibroids demanding a hysterectomy are complicated with diseased append- ages the disease of the adnexia should be treated in the ordinary way, and then the hysterectomy should be carried out on the lines best suited to the case. Cysts of the ovary, without adhesions, scarcely com- plicates a hysterectomy for fibroids. The pedicle of the tumor is at once ligated with strong silk or clamj^ed with strong forceps and the tumor removed. If it is of considerable size it may first be emptied with a trochar. Pyosalpinx should be attacked as though no fibroid existed. If there has been bilateral disease of the appendages with extensive peritonitis and numerous adhesions, the adhesions should be carefully separated and the diseased pus tubes and ovaries oarefully enu- cleated and removed. Then the uterus is removed in 170 the ordinary way. The matter of drainage should be dealt with here exactly as when no hysterectomy fol- lows, except that it may oftener be more convenient to drain through the vagina. If enucleation of the appendages has been such that large peritoneal adhe- sions have been separated and there is considerable unavoidable oozing from raw surfaces, some form of drain is imperative. As the most dejpendent portion of the ijelvis is Douglas's cul-de-sac, one should select that point from which to make vaginal drain. Fig. 30 crudely represents an instrument I have devised for opening the cul-de-sac and guiding my drainage gauze into the vagina. The lower instrument represents a staff which is placed in the vagina as a guide, with a Figure 30. tubular end which will act as a counter pressure for the pointed dressing guide which penetrates the cul-de- sac from the pelvic cavity. The upper instrument is a hollow forcei^s with pointed blades, which when they have penetrated into the vagina guided by the staff are opened and a strip of gauze of any size may be pushed ]')etween them and drawn through from below. The tubular forceps may also act as a guide for a rubber drainage tube. Those who have attempted to place drainage tubes or gauze without a i^roper guide will ajjpreciate the advantage of this instrument. So, after the uterus is removed a roll of sterilized strip gauze about the size of the index finger should 171 be drawn through the cul-de-sac into the vagina, the vagina loosely packed with gauze below and a packing left in the lower part of the pelvis sufficient to take care of any oozing from the peritoneal surfaces, Fig. 31. The toilet of the peritoneum is completed as in ordi- nary cases and the abdominal wound closed. The dressing used as a drain is removed as soon as it no longer soils the dry dressings which are placed in con- tact with it at the vaginal outlet, usually from twenty- four to forty-eight hours. Figure 31. 5. Suppurating Fibroids — Infected fibroids in which there is extensive interstitial suppuration are extremely rare. I have not seen more than two such cases in my experience. One of these I removed. The tumor had been infected more than a year before I operated on it. Several abscesses formed at inter- vals in4he interior of the walls of the large uterus and then discharged through the cervix. The case 172 failed to successfully drain after several operative pro- cedures which I attempted through the cervix. Finally I decided to do a complete abdominal hyste- rectomy, one which would also include the infected cer^'ix. The operation is performed practically as described above for the complete removal of the ute- rus including the cervix. Extreme care must be main- tained to proteCc the abdominal contents and perito- neum from the infected contents of the uterus. If the vaginal track is employed for drainage,it should be thor- oughly cleansed first by a competent assistant who is not allowed to further participate in the operation. All drain gauze should be drawn from above downward, never the reverse. 6. Tumors coinpliccded icith Pregnancy. — Fibroid tumors of large size complicated with pregnancy de- mands the sacrificing of the product of conception and the removal of the uterus. Symptoms: The symptoms of pregnancy are usually all present in an exaggerated form. Men- struation which has heretofore been excessive and frequent on account of the fibroid will cease abruptly. The tumor will begin to grow rapidly. Pressure symptoms are much exaggerated. The bowels and bladder will become crowded and sacralgia and dys- uria will result. In a word, all the ordinary symp- toms of growing fibroids of the uterus minus hem- orrhage, and all the classical symptoms of pregnancy, will become magnified to a painful degree. Pedunculated fibroids of the subperitoneal variety, with small thin pedicles complicating pregnancy may be removed in the manner described in this lecture under the head of pedunculated fibroids, without dis- tur})ing the contents of the uterus. If the tumor involves the uterine walls to any marked degree and the tumor is so large that it will prevent full develop- ment of the fetus or its development to the point of viability, or the tumor's jjosition is such that it will interfere with the jjregnancy taking its proper course, the entire uterus should be removed with the tumor. 173 if it is considered necessary to remove the tumor at once. If pregnancy is known to exist before an o^^era- tion is determined on for the removal of the tumor, as a rule it would be safer to empty the uterus as an early preliminary measure, if it is feasible, reserving the operation on the tumor for a time after convales- cence from the abortion is accomplished. Operation: However, if it actually becomes neces- sary to remove a fibroid uterus complicated with preg- nancy, either as a matter of choice, or accident from mistaken diagnoses, the operation is proceeded wdth exactly along the lines of an ordinary abdominal hys- terectomy. As a rule under these circumstances, the broad ligaments are loose, and the uterus freely mov- able making a hysterectomy comiDaratively easy. Any complication should be dealt with as in ordinary cases. 7. Extra-peritoneal Fibroids. — It is not infre- quent that one w^ill find in multiple fibroids that one or several of the centers of growth have developed low in the pelvis and in their increase in size they have gradually elevated the peritoneum and grown beneath it until they have become actual extra-perito- neal growths. The degree of such complication vary much in different cases, from a small nodule growing beneath the peritoneum from the cervix to a tumor weighing several pounds elevating the peritoneum in an irregular manner and distorting all the organs of the pelvis. Method of Procedure: These cases are all subject to removal if they are handled in the projper manner. They must be enucleated. The peritoneum covering the abdominal surface of the tumor must be carefully severed at its point of deflection from the tumor on to the parietes. The tumor should then be grasped with strong blunt toothed vulsellum forceps and while traction is being made to deliver the tumor the fin- gers should carefully enucleate the growth from its bed. Great care should be observed in order to enu- cleate it perfectly and free it absolutely from the ure- 174 ters or the rectum walls. By following the enuclea- tion the tumor will finally lead to its pedicle which will be the uterus. The cavity from which it is enu- cleated should be packed temporarily wdth sterilized gauze sponges in order to check serious oozing. When the tumor is finally enucleated and removed, together with the uterus, in the ordinary manner, the work of making a pelvic floor must be accomplished. If there is not peritoneum enough left to cover the floor of the iDelvis and a large raw surface is inevit- able, this should be drained into the vagina by a roll of gauze an inch in diameter with a packing in the pelvis sufficiently large to cover the denuded surface. Occasionally the cavity from which the tumor is enu- cleated may be packed with gauze and drained into the vagina as a subperitoneal pocket and the perito- neum closed over it. As a rule these cases require drainage. IN DEX. A Abdovien: Contour, with fibroids 19 Abdominal auscultation .... 22 Abdominal electrodes 50 Abdominal Hysterectomy 153 Complete removal 157 Complicated cases 165 Drainage 170 Extra-peritoneal method. . .156 History 155 Indications 160 Intra-peritoneal method. . . .156 Stimpson-Baer method. . . . IGO Technique 161 Vaginal fixation 158 Abdominal incision S3 Abdominal palpation 22 Abdominal Avound-closing. . . 132 Adhesions 126 Adhesions following laparoto- my 85 After-treatment: "Bowels 89 Care of glass drain 8» Care of gauze drain 88 Diet 90 Dressings 88 Forceps 150 Laparotomy .87 Vaginal Hysterectomy. . . . 150 After-treatment of laparotomy. 87 Albert, Dr 157 Abdominal Hysterectomy . . 157 Aloin 28 Alteratives 29 Ammonium muriate 29 Analysis of cases. .* 138 Anteversion 23 Antifebrin 31 Antipyriu 81 Ajjpeiidaties: Diseased 126 Removal of 117 Arrangement of operating room. 79 Arsenic 29 Artificial menopause 117 Asafedita 33 Ashton, Dr b5 Astringents 33 Astruc: Nerves in myomata 8 B Ballottement 25 Baths for fibroids 28 Battery: Office 47 Portable 46 Primary 46 Battey operation 117 Belladonna 32 Bidder: Nerves in myomata 8 Bimanual examination 21 Bladder: Effects of fibroids 18 In vaginal hysterectomy. . . 149 Blood supply of uterus 118 Blood vessels: In fibroids 8 Effect of galvinism 53 Blue mass 30 Blundell: Vaginal hysterectomy .... 136 Boeckmann sterilizer 71 Booth, Dr 74 Bowels: After-treatment 89 Preparation gi Bromids 31 Burnham, Dr 15.5 Byford, W. H. Administration of blue mass. 30 Byford, H.T 158 Clamp forceps 142 Ergot for fibroids 40 Vaginal fixation of stump . . 158 C Calumbo 28 Cancer of uterus . 24 Cannabis indiea 32 Capillary drain iso Cascara sagrada :.8 Cataphoric action of galvanic current 55 Catgut 70 Cells: ■ ■ . . - Diamond carbon 47 Law 47 Le Clanche 47 (■ern'x: In pregnancy 25 Position Avith fibroids 20 Chloral 31 Chlorid of iron 34 Chlorid of zinc 34 Cinchona 28 Clamp forceps 142 Clay electrodes .51 Closing abdominal wound. . . 132 Complications in livstorectomy.165 Cohnheim's etiology of fibroids. 14 Constipation 19 Constitutional disturbances . . 19 I INDEX. Copper electrodes 52 Curettement 116 Current, street wire 47 Czernv '. Vaginal hysterectomy 136 D Deformity produced by fibroids. 19 Delbaeh: Vaginal hysterectomy .... 13b Diagnosis of fibroids 17 Diet 90 Differential diagnosis of fibroids 23 Diseased appendages 126 Diseased appendages in abdom- inal hysterectomy 169 Dorsett, Dr 93 Douches: After vaginal hysterectomy . 151 Preparatory 83 Drainage ^°* In fibroids 1<0 In oophorectomy 127 Dress 1° Dressings. • • • .°° Dressing the wound irfo Dudley: ^ _. Vaginal hysterectomy .... lab Dupuytren : Nerves in myomata v Dysmenorrhea, with fibroids. . 18 E Eastman : Abdominal hysterectomy. . . Elect r if ity: Apparatus Current Indications for use Electrodfft Abdominal Clay Copper Flexible Intrauterine Rectal Vaginal Emmet: Etiology of fibroids Ergot: Duration of treatment . ... I'lTect on interstitial fibroids Effect on intramural fibroids Effect on submucous fibroids Eff(-ct on peritoneal fibroids Indications .• • • • M<'thod of administration . . Physiologic action Results Es.selman : Vaginal hysterectomy .... 'vaginal hysterectomy .... Extra-peritoneal fibroid .... F Ferguson stitch Fibrocysts 157 46 46 57 50 50 51 52 51 51 52 52 14 43 . 38 . 38 . 38 . 88 39 41 37 4^1 136 i:^(; n:; 9 Fibroids: Anatomy 5 Carcinomatous degeneration, 11 Classification 5 Degenerative changes 9 Diagnosis 17 Electricity in 46 Etiology 13 Histologic changes 7 Medical treatment 27 Minor surge rj- 114 Spontaneous disappearance . 11 Spontaneous expulsion. ... 12 Suppurating 171 Symptoms 17 Treatment 26 Floating kidney 20 Fetal movements 25 Fetal heart tones 25 Forceps 150 Functional disturbances .... 18 G Galvanisin: Applied to treatment of fibroids 56 Chemic reaction 53 Effect on blood vessels. ... 53 Etfect on living tissues. ... 53 Effect on microbes M Effect on sensibility 53 General effect 56 Interpolar effect 54 Polar effect 53 Garrigues : Histology of myomata 7 Gauze 76 General astringents 35 General tonics 27 Getting up 152 Glass drain 128 Glass syringe 129 Goffe: Abdominal hysterectomy . . 157 Goodell's dilators 116 Gottschalk, Prof 93 Gusserow : Disappearance of fibroids . . 12 H Hartz: Nerves in myomata 8 Hegar : Abdominal liysterectomy. . . 155 Hegar's operation, . . .... 117 Hildebrandt : Ergot in treatment of fibroids, 40 Hofmcier : Alxlominal hysterectomy. . . 157 Hydrastis Canadensis 85 Hyoscyamus 28 Hy])OSulpliites 28 JIi/HtcrrctD'iin/: Abdominal. ..." 155 Vaginal 135 Inoperable cases 61 INDEX. Instrument: Used in vaginal drainage. . . 170 Instrumental examination. . . 21 Internal electrodes 51 Interpolar electrolysis 56 Interstitial tumors of cervix . . 168 Intestinal obstruction 85 Intrauterine electrode 51 lodin 29 Iron 34 J Jones, Dr. Mary A. Abdominal hysterectomy. . . 157 K Kelly: Abdominal hysterectomy. . .156 Kidneys SO Kimball, Gillman: Abdominal hvsterectomv. . . 155 Klebs : Etiology of fibroids 13 Kleeberg : Abdominal hysterectomy. . . 155 Kleinwachter : Etiology of fibroids 13 Koeberle : Abdominal hysterectomy. . . 155 Fibrocysts 10 L Lane: Vaginal hysterectomy .... 136 Langenbeck : Vaginal hysterectomy .... 130 Laparotomii: After-treatment 87 For removal of ovaries . . . .120 For removal of uterus .... 155 Preparation of bowels .... 81 Preparation of patient .... S3 Latta: Abdominal hysterectomy. . . 155 Vaginal hysterectomy .... 136 Leopold : Theory of fibrocysts 10 Ligation of uterine arterie><: After-treatment 98 Report of cases 100 Selection of cases 98 Technique 94 Ligatures 68 Ligatures in vaginal hysterec- tomy 149 Lithotomy pcntion : For ligation of arteries . ... 94 For vaginal hysterectomy . . 139 Lymphatics in fibroids 9 M Marcy : Abdominal hysterectomj'. . . 157 Martin, Dr .155 Medical treatment of fibroids . 27 Meinhert : Abdominal hysterectomy . . . 158 Membranous electrodes. . . . . 51 Menstruation -with fibroids. . . 18 Mercury 29 Mllliampere meter 49 Minor surgery: Submucous fibroids 114 Mitchel : Etiology of fibroids 15 Morcellement: Accidents 148 Indications 144 Remarks 148 Technique 144 Uterus more than doul>le. . . 146 Variations 146 Myomata : Histology 7 N Nelson : Report of treatment with ergot 45 Nephritis 81 Nerves in fibroids 8 Nitrate of silver 35 Nux vomica 28 O Objective symptoms 20 Olshausen : Abdominal hj'Sterectomj-. . , 157 Ooptiorcctomij : Adhesion.s 126 After-treatment 133 Drainage 127 Dressings 133 Exploration 122 Indications 120 Operation 121 Vaginal drainage 130 Operating room 66 Opium SS Orarian cyxt: Diagnosis 25 P Parkes : Abdominal hysterectomy. . . 157 P(^an: Abdominal hysterectomy. . . 155 Pedicle: Of submucous fibroid 115 Pedunculated tumors 165 Pelvic examination 20 Phenacetin 61 Polk : Abdominal hysterectomy. . . 158 Pozzi : Etiology of fibroids 13 Fibrocysts 9 Histology of myomata .... 8 I'regiiaiicy: Complicating fibroids 172 Normal 24 Tubal 25 Prepared foods 28 Prcixirittion i>j: Catgut. . ." 72 Hands 78 IV INDEX. Patient 80 Vagina 83 Price, Joseph l"i^> Pyoktanin 73 Pyosalpinx 120 Q Quassia 28 Quinin 28 R Recamier: Vaginal hysterectomj- .... 136 Rectal electrodes -32 Rectum with fihroids 1« Removal of appendages 117 Removal of cervix 168 Results of vaginal hysterec- _ tomy 1-53 Retroversion 23 Rheostat— xMcIntosh 48 Robinson, Dr. Byron 119 Roux: Vaginal hysterectomy .... 136 S Sauter i Vaginal hysterectomy .... 136 Schroeder's abdominal hyster- ectomy 1-56 Sedatives 31 Seibold : Vaginal hysterectomy .... 136 Senn: Abdominal hysterectomy. . . 160 Etiology of fibroids 14 Sensibility: Effect of galvanism 53 Silk Jl Silkworm gut /I Sims' position 34 Speculum 22 Sponges 74 Stenli/ers o» Stimson-Raer: Abdominal hysterectomy. . . 156 Storage batteries 48 Stramonium 32 Strychnia 28 Subinvolution 23 Submucous fibroids 114 Stump in abdominal hysterec- tomy 103 Superficial stitches 133 Suppurating fibroids 171 Sutttm, Bland: Blood vessels in fibroids ... 8 Fibrocysts 9 Histology of fibroids 7 Sutures 68 Syringe 129 T Tait operation 117 Terfmiiiiif;: Abdominal hysterectomy . . 161 Application of electricity. . . 58 Ligation of uterine arteries. . 94 Oophorectomy 121 Vaginal hysterectomy .... 138 Treatment of fibroids: Abdominal hysterectomy. . . 155 Electrical 58 Ligation of uterine arteries . 92 Medical 26 Minor surgical 114 Morcellcment 144 Vaginal hysterectomy .... 135 Trendelenburg position .... 165 Tubal pregnancy 25 Tumors: In l)road ligament 167 Complicating pregnancy. . . 172 U Urination 19 Uterine artery— ligation .... 92 Uterine contractions 18 Uterine disinfection 139 Uterine sound 22 Uterus: Position with fibroids 20 V Vagina in pregnancy 25 Vaginal douche 83 Vaginal electrodes 52 Vaginal fixation 158 VcujindL hi/stcrectomi/ : Accidents 148 After-treatment 150 Bj' morceilement 142 Douches 151 Drainage 143 Dressings 151 Forceps 142 Getting up 152 History 135 Indications 138 Ligatures 149 Operation 139 Results 153 Technique 138 Vaginal ligation 92 Van de Walker: Abdominal hysterectomy. . 156 Velpeau : Etiology of fibroids 13 Virchow : Classification of inyomata. . H Fil)rocysts 9 W Wells: Etiology of fibroids 15 Winkle: Bhiod vessels in myomata . . 8 Etiology of fibi'oids 13 Nerves in inyoinata 8 Z Zweifel : Abdominal hysterectomy. . . L)7 J. J. COLUMBIA UiNivr^ivoi This book is due on *e. date indicated be,^^^^^^^^ expiration of a definite P«"f.f ^[^Itty or by special ar- as provided by the rules of the Library or rangement with the Librarian in charge. C«a( 1 t 40) M 1 00 JAN 1 6 10^ rv^fe Qi^rV^.J^^^^' W J-,«\.< ' I «c: — :m.' li J'- s-v' '•" tj-i.-/- ! h 1- . ' \ ^Y v't«3 • g Ji ftJi Si!*