>.;•...• <** **> v v *••- ^&» A o v %•; Lf» ^ v > 1 •iiw> > v v »*•■- SPECIFIC DIAGNOSIS: STUDY OF DISEASE WITH SPECIAL REFERENCE TO THE ADMINISTRATION OF REMEDIES. BY JOHN M. SCUDDER, M. D.. PROFESSOR OF PATHOLOGY AND THE PRACTICE OF MEDICINE IN THE ECLECTIC MEDICAL INSTITUTE ; AUTHOR OF THE PRACTICE OF MEDICINE ; THE PRACTICE OF MEDICINE IN DISEASES OF CHILDREN ) THE PRINCIPLES OF MEDICINE J DISEASES OF WOMEN J ON THE USE OF INHALATIONS ) SPECIFIC MEDICA- TION AND SPECIFIC MEDICINES, ETC., ETC. CINCINNATI: WILSTACH, BALDWIN & CO., PRINTERS. 1874. Entered according to Act of Congress, in the year 1874, BY JOHN M. SCUDDER, In the office of the Librarian of Congress. PREFACE. In presenting this volume to the profession, as a com- panion to "Specific Medication and Specific Medicines," my object has been to make a study of the prominent ex- pressions of disease, with reference to the administration of remedies. However learned we may be in pathology, and associate branches of medical study, unless we can make our knowledge point to means for the relief of suffering, the arrest of disease, and restoration to health, it will be of but little use. We believe that the expressions of disease are uniform, and always have the same meaning, and that the action of reme- dies is something definite aud uniform — "that like causes always produce like effects." If we properly study our cases, so as to determine a definite condition of disease, and know the direct action of remedies in such conditions, we will have a certain and rational practice of medicine. IV PREFACE. I concede that the study is difficult, but it is difficult principally because it is new, and sufficient observations have not been made. Physicians have so long practiced by rote, and taken it for granted that there was no "certainty in medi- cine," that we have not the material we would wish for spe- cific diagnosis. But attention is being directed to it, and the time is coming in which the field will be full of observers. No apology is made for the shortcomings of this little book, though I hope that in the main, experiment will prove the correctness of its statements. It would be singular if there were not some errors, and some things to be corrected by further experiment and study. It does not profess to be a complete treatise, or to give all the information that might be thought desirable. But it is a study of disease, which may be continued by other books and at the bed-side of the sick. If it serves the purpose of stimulating investigation and thought, pointing the road to a better system of medicine, I will be fully compensated for the labor. Cincinnati, Nov. 15, 1874. ON THE STUDY OF DIAGNOSIS. XT/E wish to make a new study of Diagnosis— one that will show us the relation between symptoms of disease and the curative action of drugs. Evi- dently this is what we need to give us a rational prac- tice of medicine — very certainly it must be the founda- tion of specific medication. It is yet the opinion, that " diagnosis " has reference to the classification of disease according to the received nosology ; that it means naming the affection " bilious fever," "typhoid fever/' " pneumonia," " nephritis," etc. And so it does with the genus doctor, at large, and their souls travail in diagnosis until a suitable name is deliv- ered. And then they consult their memories and books for recipes to throw at this name, which to them seems almost an entity. It looks absurd when thus plainly stated, yet it is true to a far greater extent than the majority suppose. If we examine the literature of the profession, we find that writers on the "Practice of Medicine" labor to (9) 10 STUDY OF DIAGNOSIS. make diagnosis in this way, and so arrange the symp- toms of disease that their readers may be enabled to follow in their lead. The student would certainly think, from this teaching, that getting a name for a disease, was the first and principal object in medical practice. Not only does this seem the principal, but the only end of medical study, and men pride themselves on their skill in naming diseases — calling it diagnosis. What can be more natural than that medicines should be prescribed at names, when so much trouble is taken to affix them ? And so we find that treatises on thera- peutics are efforts to associate drugs with names of dis- ease, with a — " this has been used with advantage" — "this has been employed in," etc., etc. The trouble is that almost every remedy in the materia medica has been prescribed at the more common diseases — pneu- monia, for instance — and the student has difficulty, not from the paucity of his means, but from their abun- dance. Some go a little further than this. They want a name for their disease, it is true, but they also make their diagnosis extend far enough to guide their thera peutics. Thus they determine a condition of the stom- ach that indicates an emetic, constipated bowels a ca- thartic, dry skin a diaphoretic, scanty urine a diuretic, periodicity Quinine, sleeplessness or pain an opiate, heat and dry skin baths, etc. Add to this counter-irri- tation for the relief of local disease, and we have the ordinary round of treatment. This kind of diagnosis is well enough — is very much better than that which simply names the disease — but it also is very crude at times. For we find at times that there are very much better means to relieve the stom- ■Mid STUDY OF DIAGNOSIS. 11 ach than an emetic; and that in some, where seemingly- indicated, it would do more harm than good. That constipation is not an indication for cathartics, and that this class of remedies are so used as to do a vast amount of harm. That impaired secretion from the skin does not mean diaphoretics ; for when most indicated they will frequently not cause secretion ; and that other means, not directed to the skin, will cause it. That scanty urine does not mean diuretics, for they will fre- quently fail to influence the kidneys when they seem to be indicated most, and will sometimes still further ar- rest secretion. Periodicity does not always mean Qui- nine, for Quinine fails nine times where it succeeds once, sometimes intensifying disease, at others produ- cing a disease peculiar to itself — quinism — worse by far than the disease for which it is given. And sleepless- ness does not mean Opium, for it fails frequently, and, as generally used, does far more harm than good. It is still worse when the physician thinks he sees the need^ of cathartics, diuretics, diaphoretics, tonics, Quinine, nervines, etc., and gives them all at once, or in a miscellaneous hodge-podge. The common result is to intensify the disease, derange the stomach, and impair the vegetative nervous system. The remedies are fre- quently given so that the action of one opposes that of another, as for instance a cathartic with a diaphoretic, or at such times that they can not possibly do what they are intended for. How, then, shall we study diagnosis ? Is there any better method than that usually pursued ? I believe there is a right way to study diagnosis — one that will prove satisfactory to patient and physician — will name the disease for the one, and determine a ra- 12 STUDY OF DIAGNOSIS. tional therapeutics for the other. Such a way I endeav- ored to point out in my Principles of Medicine, to which my readers are referred for my opinions in extenso. Man has but one body, and though it may be divided into parts, each has the same life, is supplied from the same blood, governed by the same nerves, and has the same nutrition and waste. Only in so far as drugs act on special parts or organs, need we study disease of these independent of the organism at large. Man has but one life, and it is the same for all parts. The normal manifestations of this life we call health ; the abnormal manifestations of it disease. If we can always think of disease as a method of life, in a living body, we will have gotten rid of an old error, and have made the first step toward a correct diagnosis, and a rational therapeutics. Disease, then, is not an entity — something to be for- cibly expelled from a living body — but is actually a method of life. It can not be purged from the bowels, vomited from the stomach, strained from skin and kid- neys, or exorcised by counter-irritation. Such means may do good, as when they remove an offending sub- stance, or when they establish a function that is defi- cient, but they should have a rational use. The life of disease is not as good as the life of health, neither in the whole nor in any individual part. It is always exhaustive, impairing the life now, and the life to come by renewal of tissue. It makes no difference what may be the seeming condition of the body or a part in disease, the real condition is, an impairment of life. We study disease, therefore, as a method of living ; and we treat the diseased body as a living body, which STUDY OF DIAGNOSIS. 13 has been placed in such position that its life has been enfeebled or deranged. We next want to understand clearly the structure and uses of the various parts of this one body. We want to know clearly the conditions necessary to healthy life, and how their change works that we call disease. If we can understand clearly the relation of a condition or function to healthy life, we are in a position to learn how the change in condition or function produces dis- ease, and a correct therapeutics is at once suggested. Examining the human body, we find certain condi- tions and functions underlie others, and seem to be first elements in the sum of life. Of these I may name tem- perature, circulation, innervation, nutrition and waste, and the blood. We always study these first, and we want to know the exact character of the wrong, in one or all, and how that wrong may be corrected. Going one step farther, we want to know the relation of these conditions and functions to one another. There is a general relation in health ; possibly they are of equal importance in the problem of life. But in disease one or other may stand first, and serve as a basis for wrong of life in many directions. Thus a disease involving every function of life, may arise in a wrong of the temper- ature and circulation of the blood. There is a want of appetite that tonics will not reach ; a wrong of secre- tion that can not be righted with cathartics, diaphoretics and diuretics ; a wrong of innervation that can not be reached with narcotics and nervines. Direct remedies that restore normal temperature and circulation, control the entire process of disease ; like a card-house, the re- moval of a first card is sufficient for the overthrow of the entire structure. 14 STUDY OF DIAGNOSIS. It is not so easy, always, to determine which wrong is thus first, yet with care it may be determined — and this is an essential in good diagnosis. A disease pre- senting similar symptoms — the same symptoms to an ordinary observer — may rest equally upon a first lesion of the circulation, innervation, nutrition and waste, blood-making, or the conditions of the blood. We want to know which stands first, and then rectifying the first wrong the treatment is easy and successful. Disease has certain expressions, which we call symp- toms, as health has certain expressions. We find that the manifestations of life in health are very uniform, and consistent, and one can hardly mistake their meaning. So in disease, the expression of morbid life is uniform, and constant, and does not vary in different individuals, as many have supposed. If we determine in any given case the expression of diseased life, we will find it the same in all cases. It has been claimed, and tacitly admitted that symp- toms of disease were so changeable and inconstant, that they could not be depended upon with any certainty. This was certainly true to those who made their di- agnosis according to the recived nosology, and then pre- scribed at the name. For as very diverse pathological conditions would be grouped under each name, the symptoms would of course vary, and the treatment would show the element of uncertainty in so marked a maner that idiosyncrasy would be constantly called in to explain the trouble. We propose studying the expressions or symptoms of disease with reference to the administration of reme- dies. It is a matter of interest to know the exact char- acter of a lesion, but it is much more important to know STUDY OF DIAGNOSIS. 15 the exact relationship of drug action to disease expres- sion, and how the one will oppose the other, and restore health. If I can point out an expression of disease which will be almost invariably met by one drug, and health restored, I have made one step in a rational practice of medicine. I have no hesitation in affirming that if we have once determined such relationship, we have determined it in all diseases alike, in all persons, and for all time to come. If, with this symptom or group of symptoms, my Aconite, £fux or Podophyllin cures to-day, it will cure to-morrow, next year, and so long as medicine is practiced. If it cures Tom, it will be equally applicable in the same condition to his father, mother, wife, or mother-in-law. " Do you. mean to say," asks the reader, " that the present system of nosology is useless? " Yes, so far as curing the sick is concerned, that is just what I mean to say. Not only useless, but worthless — a curse to physician and patient — preventing the one from learn- ing the healing art, and the other from getting well. But you may ask, "how would you make out the certifi- cate for the Undertaker V That's just what we wish to avoid, we don't care about furnishing subjects, and would very much rather people should die of old age, and then we would write it in English — " old age." The first lesson in pathology we want to learn is, that disease is wrong life. The first lesson in diagnosis is, that this wrong finds a distinct and uniform expression in the outward manifestations of life, cognizable by our senses. The first lesson in therapeutics is, that all remedies are uniform in their action ; the conditions be- ing the same, the action is always the same. We learn 16 STUDY OF DIAGNOSIS. to know the healthy man — know him by exercising all our senses upon him. We want to know how he feels, how he looks, how he smells, how he tastes, and what kinds of sound he makes. Then we want to learn tho diseased man in the same way, and compare him with our healthy standard — certain expressions of life mean- ing health, and certain other expressions meaning dis- ease. Then we study the action of drugs upon the sick, and when we find them exerting an influence op- posed to disease and in favor of health, we want to know the relation between the drug and the disease — between disease expression and drug action. I do not say that we should not study drug action in health — indeed I think it a very important study. You may, on your own person, study a wholly unknown drug, and determine its proximate medicinal action. How ? Easy enough. You will feel where it acts ; that points out the local action of the drug, and as a matter of common sense, you would use it in disease of that part, and not of a part on which it had no action. You will feel how it acts — stimulant, depressing, altering the innervation, circulation, nutrition and function. If now you want to use it in disease, use it to do the very things it did in health, and not as our Homoeopathic brethren would say, to do the very opposite things. This might not seem altogether pertinent if we were studying old diagnosis, but new diagnosis means medi- cine, and must point out the cure for the particular case in hand. STUDY OF DIAGNOSIS. 17 THE STUDY OF LIFE. The diagnosis that wc are studying has a physiologi- cal basis, and we want to learn something of the hind of physiological knowledge necessary. Is it that which may be learned from Carpenter, Draper, Huxley, etc. ? Most decidedly it is not. The knowledge from books is most important, excellent in its place, but worth nothing here unless supplemented by a new study. We must study the living man, and learn to recognize every manifestation of this life by our senses. Nothing less will serve the purpose in rational med- icine. We want to bring our own senses to bear upon him, and hnow how he feels, tastes, smells, and how he looks and what sounds he makes. This study of the living man, the most important study in medicine, is al- most wholly neglected. Men live a lifetime, and know nothing of the manifestations of life. Students become conversant with books, attend their lectures, pass their examinations, and yet have no practical knowledge of human life. And physicans will practice medicine a life- time, and yet fail to know what healthy life is. How would you make a good surgeon ? There is but one way. He must exercise his senses on the human body, and learn to know it for himself. He studies upon the cadaver, and learns the relation of parts; and he also studies che living man, and learns to recognize these relations by the sense of touch. Your accom- plished surgeon recognizes a displacement or fracture, as soon as his eyes rest on the part. Let him pass his fingers over a limb in the dark, and he will tell you if anything is wrong, and just what the wrong is. He is a good surgeon, just exactly as he is an expert in this. 2 18 STUDY OF DIAGNOSIS. Not a year passes but what we have one or more suits for malpractice against physicians of our school, arising out of bad bone-surgery. (They have quite aa many in other schools.) Why these cases ? Simply be- cause they have not taken the trouble to learn on the cadaver and living body for themselves, just how it is made, and the relation of one part to another. Any man, whether he is a surgeon or not, can so train his senses, and know the anatomy of man, that mistakes would be impossible, and cases of malpractice would be the result of accident, or the fault of patients. I say to the student, study anatomy and physiology on the living man. Observe him closely with your eyes, until you learn his varied expressions. See him walk, sit, lie, work, eat, breathe, talk, etc. Feel of him, and see how he is made, and what he feels like in different parts. Learn every prominence of bone in the body, and its relation to articulations, blood-vessels, nerves, organs, etc. Hear every sound he makes, and learn to recognize its character. And, lastly, learn to recognize all of the many smells of which he is the base. Learn him from the crown of his head to the sole of his foot, and analyze him with your own senses, and you will have the foundation for a good physician. I place very great stress on this method of studying physiology, and recommend it to the old practitioner as well as the medical student. No knowledge in the memory can take its place. It must be the basis of a rational practice of medicine, for unless we know what health is, we can not know disease, and unless we know disease we will have a random and very uncertain therapeutics. I have already called attention to the necessity of STUDY OF DIAGNOSIS. 19 training all our senses so that we may be able to observe well. These faculties are like many others, they may be so trained under the influence of the will, that after a time they work automatically, and with a rapid- ity that is astonishing. This is the work of time — but time placed where it will do the most good. All that one need do, to have good, active senses, is to use what he has rightly. There is no mistake about these things, and I will guarantee any physican a success that will astonish him, if he will put them in practice, Need I say that the reward is great. Outside of professional reputation, and the ordinary rewards of successful business, there are sufficient returns. A man's conscious life is in and through his senses, and as these are educated and en- larged, his life becomes larger, and his pleasures in- creased. Nature is a most bountiful mother, and her laws bring certain compensation ; and of these there is none truer than that " a man grows as he is rightly used." Applied Anatomy. — The ordinary study of anatomy is a good thing, and is the basis for a sound medical education. Yet T am sorry to say that the study of anatomy with the majority of physicians is very *• ordi- naiy." It is a good thing to be able to name the various bones, processes, muscles, and organs of the body, but it is very much better to know them, as a man knows his best friend. I may know a man's name, and yet know really nothing about him, physically, mentally, or morally. So it is in the common study of anatomy, the memorizing of names takes the place of that study which will enable one to really know the structure of the human body. 20 STUDY OF DIAGNOSIS. A good anatomist will strongly insist on dissection as an important means of learning. He well understands and endeavors to impress the fact that it is only by personal examination that one may know the various tissues and organs, and their relation to one another. The surgeon supplements this by the additional state- ment that the most important preparation for the use of the knife in surgery, is the use of the knife in dis- section. K"ot only to acquire anatomical knowledge, but to know the resistance of different tissues to the scalpel, and to train the sense of touch. An accomplished pl^sician should be a good anato- mist — the skilled diagnostician is a good anatomist. No one need say he has no opportunity, for every one can make opportunity. A dead man is a good thing in this study, but any animal or part of an animal will serve the purpose of the man who really wishes to know, and there is not so very much difference between man and the remainder of the mammalia. The nearest butcher shop will furnish material in abundance — from eyes, to tongue, larynx, trachea, bronchial tubes and lungs ; the digestive canal and its associate organs ; kidneys, etc. : whilst a quarter of lamb or veal gives pretty good muscular dissection. The worthless curs prowling about the village or town, give excellent facilities for dissection or vivisec- tion. Chloroform the brute, and he is ready for work, and you may educate your touch on living tissue, as well as learn anatomy. In the olden time the study of anatomy was com- menced with the bones — not with pictures or plates of bones* This study in which bones are tangible reali- ties, and convey to the sense of touch and the eye their STUDY OF DIAGNOSIS. 21 peculiarities is the right study. Every physician should be able to recognize any bone by the sense of touch, and at once give it its proper position. Just as he should be able to recognize the normal from the ab- normal in shape, size and position. The skeleton prop- erly articulated is a valuable adjunct, and if it was thoroughly studied by the hands in a dark room, we would have but few cases of mal-practice in bone- surgery. But this study of anatomy from the skeleton, and by dissection, assisted by reading and lectures, is but pre- liminary to a more important study. We want to study anatomy upon the living man. We want to know the situation and the relation of various parts, so that we may be able to put our finger upon them at once, and detect the slightest variation. We want the impress of this living man upon our senses, so that they may know him intimately. What does he look like? What does he smell like ? What does he taste like (in so far as taste is applicable) ? What sounds does he make ? And how does he feel? We want to know his every expression, standing, sitting, lying, on his back, sides, etc. His expression in activity, and at rest. We study his muscles in life, their arrangement on the bones, and their influence in giving the body motion. We study the situation of blood-vessels in the same manner, and learn to trace their course by the prominences of bone, relation to muscles, etc., and going deeper, we study osteology again, as the bones are clothed in tissue. No man need excuse himself for want of opportu- nity, so long as he possesses a body of his own, and there are so many other bodies that might be engaged for the purpose. 22 STUDY OF DIAGNOSIS. There are two objects in this study, both important. The one is to knoiv the mechanism of life, and the other is to educate the senses. The importance of the first will not be disputed, and before we have concluded this study, I think the other will be conceded. Applied Physiology. — The knowledge of physiology from the books is a good thing, but it is not sufficient for our purpose. We not only wish to learn that Car- penter, Huxley, and others, have witnessed certain phe- nomena, and learned to know them as constant expres- sions of life, but we wish to know them of ourselves, and through our senses. Dr. Huxley introduces the study of physiology by saj T ing — " The body of a living man performs a great diversity of actions, some of which are quite obvious; others require more or less careful observation ; and yet others can be detected only by the employment of the most delicate appliances of science. " Thus, some part of the body of a living man is plainly always in motion; even in sleep, when the limbs, head and eyelids may be still, the incessant rise and fall of the chest continue to remind us that we are viewing slumber and not death. " More careful observation, however, is needed to de- tect the motion of the heart; or the pulsation of the arteries ; or the changes in the size of the pupil of the eye with varying light; or to ascertain that the air which is breathed out of the body is hotter and damper than the air which is taken in by breathing. "And lastly, when we try to ascertain what happens in the eye when that organ is adjusted to different dis- tances; or what in a nerve when it is excited ; or of STUDY OF DIAGNOSIS. 23 what materials flesh and blood are made ; or in virtue of what mechanism it is that a sudden pain makes one start — we have to call into operation all the methods of inductive and deductive logic; all the resources of physics and chemistry ; and all the delicacies of the art of experiment." Huxley is an admirable teacher, probably the best living, and we will do well to get an idea of these methods. The first lesson we learn from these brief, but expressive paragraphs is, that we are to observe this man, who " is plainly always in motion," and that we are not to be satisfied with the observations of another. Then follows the natural sequence in these observa- tions. At first the gross expressions of the body, and the difference between the man awake, asleep, dead. Next a k *more careful observation," determining the motion of the heart, etc. And lastly, the skilled obser- vation, from a trained mind, aided by the various in- strumentalities and appliances of science. Books are useful in this study, though not the object of study ; it is the man we want to know, not the book nor its author. The book may serve as a guide-board pointing the way, and at the same time give us a standard of comparison. It tells us what to exercise our senses upon — what to observe — and it informs us what others have observed, and what is the common standard of healthy activities. There is nothing in the life of the man but should be a subject of close scrutiny. We want to know him in the entirety of his action, as we wish to know^ him in every detail. And we want to know him so inti- mately and thoroughly, that this physiological man shall be always present with us as a standard of com- parison. 24 STUDY OF DIAGNOSIS. The reader will at once see the necessity of this study as a basis for diagnosis. The physiological man is the man of health, the pathological man is one who has left this common standard of being. The physiological man is the standard of measurement, the common mean that we measure from. To have a measurement at all, it is necessary to have a fixed point to start from ; this healthy man is the fixed point. Measurement has reference to certainty, and certainty is what we most desire in medicine. A measured mile is a definite distance, an imaginary mile, having its origin and termination in the cranium of Paddy Ochhone, is a very different thing, though very like the ordinary measurements in medicine. The first thing that the physician wants, then, is a sound physiological standard, which he carries with him as he makes his rounds. It is lain by the side of the patient in bed, sits by him on the chair, stands by him, walks by him, puts out its tongue, extends its hand to give the pulse, has lungs, bowels, kidneys, re- productive apparatus, etc., always at your service, and open for comparison. Disease is wrong life, and a wrong presupposes a right. To determine the existence of a wrong, we must know what the right is ; to determine the character of the wrong, we must compare it in all its parts with the standard right. This is diagnosis, as the reader can at once see. TIow now shall we get this physiological standard. Clearly by observation with our own eyes, and the use of our own senses. Each man must make it for him- self, and give it distinctness by the education of his own senses. Theoretical knowledge will not do. STUDY OF DIAGNOSIS. 25 If we take Huxley's first example, " awake, asleep, dead," we find an excellent study. Can you tell the difference between the appearance of sleep, sleep and death ? Hardly by the first glance, and possibly only by a very close examination, and some experimenta- tion, (the last especially evidences a state of uncer- tainly). But if we carefully observe the phenomena of sleep, in the infant, the child, the adult, we will soon have a healthy standard, and the expressions of sleep are so distinctive, that no one could deceive us by shamming sleep. So, too, if we carefully observe and study death, we will never mistake it. There are distinct expressions of body in death that can never be counterfeited. It is not only the absence of motion, of respiration, of pulse, or heart-beat, of heat, but there is an absence of the expression of life in its totality, and an expression of lifelessness that is characteristic. The relaxation of death is distinctive, as is the rigor-mortis, as is the de- composition of tissue. It is a good thing to have a standard of death for comparison as well as of life. Not that we usually have any doubt of death, but that we require it as a measure of life. It is well to have two points to mea- sure from — the standard of life and the standard of death. There is an approximate death, as well as a total death ; a dying by degree, or part, as well as a dying at once and in entirety. Taking a man in entirety, we find a distinct expres- sion when he walks, stands, sits, or lies. Every part of the man talks to us, his hands, his arms, his legs, his feet, even his "calves may wink," as described by Dickens in one of his Christmas stories. 3 26 STUDY OF DIAGNOSIS. We not only learn from this much of the physical life of the outer man, but learn of the life within. The expression is the shadowing forth of the underlying nervous system, and this again of the real or spiritual man behind this. As physical, mental and moral health has a distinct expression in the outer man, which we purpose using as a standard of admeasure ; so all diseases, physical, mental and moral, have a distinct expression in the outer man. You will no more find disease under a healthy exterior, than you will find a devil in the garb of an angel. We have a standard temperature, which we may learn to recognize by the hand, though it is best to measure it with a thermometer. We have a standard electrical condition as an important factor of life, which we will learn to recognize in the general expression and movement, the special expression of the face and eyes,, and by the touch. And we have a standard formative force, which we will recognize in the expres- sion of tissues, and the sensations they give to touch. We have a standard color for the general surface, and for special parts that the eye will learn to recog- nize, and use for comparison. We make this study thorough ; it is the skin at large, and then those por- tions where the circulation is less free, where it is very superficial and free, the nails, hair, veins, etc. We have a standard color for mucous membranes, for lips, gums, tongue, teeth> etc. We have a standard in touch — of smoothness, resist- ance, elasticity, size and association ; and we have it of every part of the body. Of course we have not learned it of Huxley or Carpenter, but by the use of our own hands on the human body. STUDY OF DIAGNOSIS. 27 We have a standard respiration, in frequency, full- ness, depth and freedom, which is distinct and clear, and which we know of ourselves by observation. We have a standard circulation, which we know at the radial artery, by the even, distinct, regular blood wave that passes under our finger, as well as by the ex- pression and color of the surface, and the expression of parts associated with the heart in action. We have a standard condition of the digestive organs, which we learn from books and by observation. It don't take long to learn, even by the general expres- sion, and the special expression of the muscles of the mouth, whether a man has a good appetite, good diges- tion and good blood-making. Even constipation will be shadowed forth in the outer man so that one may re- cognize it. Blood-making and nutrition must have distinct ex- pression, and a standard for measurement will be readily formed, for all functional activity is dependent upon nutrition. The standard of healthy excretion by skin, kidneys, and bowels is readily formed by observation. Not ob- servation on the sick, and under the influence of drugs, as many suppose, but upon the well. Thus we see it is possible to so learn our physiology, that it may serve as the basis of a rational practice of medicine. And I think every reader will see that this education is essential to good diagnosis, and that its at- tainment is the first object in medicine. This is not a question of schools ; it is a question of sheer empiri- cism, (call it quackery if you will), or rational medi- cine ; it is a question of whether the physician is to be a coadjutor and aid to death, or whether his influence will be upon the side of life and health. 28 STUDY OF DIAGNOSIS. METHODS OF DIAGNOSIS. Where do we find the expressions of disease ? When you think of this question a moment, it does not seem so easily answered ; indeed it furnishes good material for thought. Probably we had better preface it with another. How do we find the expressions of disease ? Man has knowledge of things external to him, by means of the general sense of touch, and the special senses — sight, hearing, smell, taste. We may ask, then, when brought in contact with the sick, what do we feel, see, hear, smell, taste, that differs from the normal condi- tion — health. What the patient feels, sees, hears, smells and tastes is not so important, for his senses are im- paired by disease, they have never been educated, and his mind is not in a good condition to receive im- pressions. I imagine the reader saying to himself — well — really — I don't know afiout that. I don't feel my patients much, and am not sure that I learn much by feeling. I see them — but — I don't know that I can tell the char- acter of disease by sight. I hear — yes — I hear all the patient has to tell me about his bowels, number of ope- rations, whether he passes wind up or down, or both, makes water, where he has aches and pains, etc. I don't smell much, unless I examine the bed-pan or chamber utensil, and I don't want to taste in the sick 100m. That is — he makes his diagnosis, from the patient's feelings, and not by the use of his own senses — a very imperfect way of making a diagnosis. We have called attention to the uncertainty of diag- nosis from " what the patient says," yet it is the com- STUDY OF DIAGNOSIS. 29 nion means of diagnosis with all schools of medicine. If the patient was wholly truthful there would be suf- ficient uncertainty, for they have little knowledge of disease, little skill in observation, and from disease they are incapacitated for reasoning. The patient can not, in the very nature of the case, know very much of his dis- ease, and does not know that little well. If now we supplement this by the well known ten- dency to exaggeration by the sick and friends, we find still more uncertainty. You ask when you visit a patient whether he slept. The wife answers — " not a wink," and yet you know from the patient's expression that he has rested during the night, though his sleep may have been broken. Or the nurse answers, " Oh, yes, he had a good night's rest," though the only ground she has for supposing so is because she slept herself, but the patient's expression shows you he has passed a restless night. You ask if the patient has taken food — " no, he hasn't been able to take a bite," though you find on persistent inquiry, that he has had broth, or milk in sufficient quantity. You ask if he has passed urine — " Oh, yes, sufficient," yet you see by the pinched, anxious countenance, and position of abdomen and pelvis, that he is suffering from retention or sup- pression of urine. You ask if the patient suffers much — " Oh, yes," is the reply, " I have had severe pain," or "I have suffered intensely," yet you see by the countenance that the statement is false cr overdrawn. I do not believe that my patients aro worse in this respect than others, yet I have occasion to say to myself every day, when listening to the patient's or nurse's story — " Madam, or sir, you are lying." Indeed, I have always made it a rule to believe nothing that 30 STUDY OF DIAGNOSIS. was told me in a sick room, unless it was corroborated by my examination of the patient. I have tried the experiment several times, of seeing how far the patient and attendants would go in their exaggeration. Take one that is imaginative, and by leading questions and promptings you can get the symptoms of every ailment to which man is subject ; and the story will have more consistence and semblance of truth, the more the patient knows of disease. The nurse is frequently as bad as the patient in this respect, and quite as easily led to exaggeration. I had an illus- tration of this a few weeks since in the person of a monthly nurse. The mother and child were doing well, yet you would think from the nurse's description that they were just on the point of having every ailment that the puerperal state would afford. The mother was not easily influenced, or the nurse would really have made her sick. Why has a good physician better success in diseases of children than in other cases ? There is no doubt of the fact, and I have heard it remarked many times — '' I would much rather treat children than adults — medicines act better." You can't question the child, and you •^arn but little that is important from the mother — hovi do you get your information ? True, the mother and Triends will say — " it is so hard to doctor children, you can't find out what is the matter with them." But a good practitioner knows better than this, and though possibly he has never thought about the subject, he knows he can treat children better than grown persons. "Why ? For the very good reason that he uses his senses, and prescribes from what he knows, instead of tv ring the say-so of patient or nurse as a basis for the STUDY OF DIAGNOSIS. 31 prescription. If I should suggest to you, that in the practice of obstetrics you should place dependence upon the statement of nurse and patient, instead of making an "examination" — you would think it most absurd. Yet, in reality, it is not more absurd, than de- pending upon the story of nurse and patient in ordi- nary diseases. If these are facts, and I think the experience of every reader must satisfy him that they are, we want to change our method and get a better basis for diagnosis and prescription in diseases of the adult. Let us sup- pose every patient a child — which they are in fact, so far as medicine is concerned — and give them the same careful examination that we would to the child, and thus reach conclusions from what we know, rather than from what patients or nurses say. We do not wish to lose the advantage of any infor- mation we may get from patient or nurses, but we pro- pose to make no suggestions in the manner or charac- ter of questions, that will bring false answers. There are some things the patient will know, and a little care will frame the questions so as to get at the real facts. There are some things the friends or nurse will know, and direct questions will usually bring straight replies. But there are many things that neither can know any- thing about, at least with any certainty, and these should always be avoided. All answers should pass in review of our own senses, and what we know of health and disease. These are the judges, and if the evidence is good it will have their approval ; if it does not have their approval we throw it to one side. We do not purpose receiving anything that is opposed to what we know of disease, and we do 32 STUDY OF DIAGNOSIS. not purpose believing anything that is opposed to the evidences of our senses. THE EDUCATION OP THE SENSES. We have already seen that the education necessary to make a good physician, is not from books, or of the memory — both good in their place, but insufficient. The education that gives the best results, and makes the successful practitioner, is of the senses, and of the brain to receive impressions, and make deductions. We have called attention to the proper study of an- atomy, by which one may know the structure of the human body of himself; and the right study of phy- siology, by which one may know the various activities of this mechanism. To make these attainments re- quires study — not midnight oil burned in reading books, but the continuous exercise of our senses upon the human body, living and dead. The same course of study is necessary to know dis- ease. The description from Aitkin, Wood or Scudder, is not the knowledge we want ; it is not what another man knows that is of advantage to us, any more than it is another man's dinner that sustains our life. We want to know disease for ourselves, and we learn it by the exercise of our senses upon diseased bodies. If the senses, then, are the instruments by which we obtain knowledge, it will at once be patent to the reader that their development and goodness will be the mea- sure of our ability and our attainments. Hence the man of educated and acute senses will be for superior to and have every advantage over the man who has not been thus trained and developed; STUDY OF DIAGNOSIS. 33 Most persons seem to think that the human senses are natural, not acquired — that they are born to us, and not the result of education. This is a very great mis- take, and a grave error to the physician. Man is born with an organism that, so to speak, has germinal capaci- ties for use, and its future development is by normal use. The child at birth has perfect hands and arms, every bone, muscle, bloodvessel and nerve being there ; but they are as yet wholly useless. Its feet and legs have all the parts of the adult, but it can not walk, or even wag its toes under the influence of the will. Its eyes are perfect, yet the images formed upon the retina are wholly without meaning, and might quite as well be a blank. The child slowly learns to use its hands, and months pass before it can hold an object, and a still further time before it can move the object in obedience to the will. We see it d&y by day learning to see, slowly taught by its surroundings. And the adaptation of the nether limbs to walking is the persistent work of the first twelve or sixteen months. Compare the child of these attainments of one year with the child of two years, and you see a wonderful difference. The education has been continually going on during this period, and with continued use in right directions comes increased devel- opment. At the third year there is further improve- ment, and thus, as we go on to the fifth, the tenth, the twentieth year, we observe a continued education of the senses, and a better development of them. I want to call attention to the fact that we find every grade of development in different individuals, from the ■first year up to maturity, and that this development does not always depend upon the original capacity. A 34 STUDY OF DIAGNOSIS. difference in use or in education, so to speak, gives dif- ferent capacities. It is not in the initial or starting point, but in the method of progress, that gives the fully developed sense. If the child has been rightly directed, and the senses have been rightly used, they will have proportionate capacity. Many who would admit that the human senses*are acquired, think of them as being acquired very much as the man increases in stature and weight, and some- thing essentially belonging to this period of growth. They conclude that the senses grow with the body, and attain maturity when it has reached the full size and stature of a man ; and now a man, having his full capacity, will find neither increase nor diminution so long as he may live. They measure a man in all his parts in this way ; his every function is now developed for life. A greater mistake could not.be made. The law of development is always in operation in the human body, as it is throughout the animal and vege- table world. As any organ or part is rightly used, it grows in capacity. Not only in infancy, in childhood, up to adult years, but each and every year of a man's life to old age. It is more marked, of course, when the repro- ductive powers are active, but it is always a law of life. The man between thirty and forty years, will lind that lie still has the germs of a large capacity, which needs but the right use for development. He may grow legs, arms, body, chest, lungs, brain, the sense of touch, of taste, of smell, of hearing, of sight, if he will ; all that is necessary is, that he should rightly use that he has. Shakspeare makes his typical Dogberry say, "To be a well-favored man is the gift of fortune; But to write and read comes by nature:' STUDY OF DIAGNOSIS. 35 But however it may be with reading and writing, very surely acute sight, smell, taste, hearing, touch, do not come by nature. We all recollect the tedious process of education — how we slowly attained our A, B, C's, and what a work we had done when we could spell b-a ba, k-e-r ker, baker — and so on through, whether it has been little or much. This is the type of education, and this is the way it is obtained — little by little, and by continuous application. But there is another view of the question, quite as important to many persons. The law is not only ope- rative in the one direction — to increase functional capacity — but quite as much so in the other direction — to lessen or take away that we have. The part or organ disused loses its functional capacity, becomes atrophied, and finally loses the power of reproduction — is wholly gone. The Indian Faakar, who vows to hold his arms above his head, finds after years are passed, that they are no longer obedient to the will, are lost. This is the oase with any part of the body — with the organs of special sense, and with the brain and its functional ac- tivities. It is the application in the human body of Christ's parable of the talents : " For the kingdom of heaven is as a man traveling into a far country, who called his own servants, and de- livered unto them his goods. And unto one he gave five talents, to another two, and to another one; to every man according to his several ability ; and straight- way took his journe} 7 . Then he that had received the five talents went and traded with the same, and made other five talents. And likewise he that had received two, he also gained other two. But he that had re- ceived one, went and digged in the earth and hid his lord's money." 36 STUDY OF DIAGNOSIS. The reader will recollect the application of the para- ble — the one who had used his talents found them in- creased ; the one who buried his, had taken away from him that which he had. The divine Teacher enunci- ated a law as wide as the universe, and as applicable to physical and mental growth, as to moral development. It is just as applicable to the training of the senses of the physician, as it is to the growth of the moral nature of man. The lesson is clear : if we want anything, we must work for it ; if we will not work, we lose that we have. Man has conscious life in his brain and through his senses. Take away his senses, and he has lost all com- munication with the world without. Through his senses he has pleasurable life, and it is deep and broad in proportion to their development. One would think that this would be sufficient incentive to their full de- velopment. But, unfortunately, men dislike work, not realizing that even this will prove a jDleasure. It is the continued and orderly exercise of parts that gives them increased capacity. Not by fits and starts, but continuously, day by day, week by week, month by month, year by year. The organs of special sense have in them a mechanism for skilled use, as well as for the gross purposes of life, and it is this skilled use we pur- pose to call forth in diagnosis. Man has five senses — of touch, of sight, of hearing, of smell, of taste — all of which are useful in this study, find all require training. The physician of unskilled touch, sight, hearing, smell, taste, can never be suc- cessful. It is hardly necessary to give examples of this, as every reader's experience will show it a truism, but a few may stimulate thought. STUDY OF DIAGNOSIS 37 In the obstetric art the skilled touch is the important element of success to the accoucheur. Without it he is groping in the dark, and is obliged to sit passively by the bedside and wait. He can not know, and of course can not give intelligent assistance when assistance may be required. In the same way the unskilled touch could never use a knife in surgery, could not pass a catheter, could not recognize the variations of the pulse, could not determine the condition of the skin, could not do a great many things that might be done if the touch were educated. The untaught eye can not distinguish the variations of form, size, color, and other physical properties of bodies, which tell of condition, and functional activity. To the extent that it is uneducated the man is blind, and of necessity is groping in the dark. The untaught ear has no use for the beautiful mechan- ism that adapts the organ to receive the varied impres- sions of sound. It can hear thunder, and it can hear noise, but to the " concord of sweet sounds " it is deaf. In medicine the ear requires education by use in order to detect some of the minute sounds, as the " respira- tory murmur," and a still further education to detect the minute shades of difference in sound, which tell of disease. The same may be said of the educated senses of smell and taste. The uneducated nose may recognize the genus stink, but has no power of analysis ; as it may recognize fragrance, and have no pleasure from it. To the uneducated taste all substances are savory, or un- pleasant, and with this gross classification the sense is satisfied. To the educated taste there is every grada- tion of the one and the other, and a power of discrimi- 38 STUDY OF DIAGNOSIS. nation that is sometimes really wonderful in its acute- ness. How may we Cultivate the Senses? — This is the really important question, though the answer has been partly given in the above study. We cultivate the senses by continuously using them, and their education is the work of months and years. We can always find objects to exercise them upon, the training school is all about us, and we have only to make intelligent use of the facilities at our command. It is well, however, to have an intelligent plan, and follow it up assiduously, recollecting that " time, patience and perseverance will accomplish all things." The senses are intimately associated with the brain, and their education implies a mental training as well. Whilst we develop the organ of sense by use, we develop the brain upon which the impression is made, and the higher brain which takes cognizance of, and analyzes the sensations. The development is thus a double one, and both are essentials in correct diagnosis. A plan presupposes thought, the act of the rational mind, as well as orderly activity.* ^Sensations and Judgment. — (That the reader may have before him a brief synopsis of the physiology of sensation, I give the following description from Huxley's Physiology:) "In explaining the functions of the sensory organs, I have hitherto confined myself to describing the means by which the physical agent of a sensation is enabled to irritate a given sen- sory nerve ; and to giving some account of the simple sensations which are thus evolved. " Simple sensations of this kind are such as might be produced by the irritation of a single nerve-fibre, or of several nerve-fibres by the same agent. Such are the sensations of contact, of STUDY OF DIAGNOSIS. 39 The Touch. — The tactile sense has its highest de velopment in the hands, and it is in this locality, espe- cially, that we purpose cultivating it. Delicacy of touch is associated with a normal condition of the skin, and necessitates care of the hands. It does not mean a life of idleness, but it means proper protection from cold, cleanliness, and an avoidance of such work as thickens the epidermis, or gives it unnatural hardness. " Clean hands and a pure heart " is a gospel expression that we can w^ell apply to medicine, both essentials. Show me the physician with rough, unpleasant, grimy hands, and I will show you the man who is unsuccessful in his calling, and is being gradually imbruted in his nature. The hand is the characteristic feature of man, and is the outer expression of the reason within, and the spirit that is above the beast. A French writer once remarked, " Show me the man's hand, and I will tell you what manner of man he is." A plan of use ? It suggests itself at once — we will exercise our touch upon every object we come in con- tact with. Here are objects large and small, long and short, rough and smooth, of varied form, with special Inequalities of surface, of varied consistence, and we warmth, of sweetness, of an odor, of a musical note, of whiteness, or redness. " But very few of our sensations are thus simple. Most of even those which we are in the habit of regarding as simple, are really compounds of different sensations, or of sensations with ideas, or with judgments. For example, in the preceding cases, it is very difficult to separate the sensation of contact from the judgment that something is touching us; of sweetness, from the idea of something in the mouth ; of sound or light, from the judgment that something outside us is shining, or sounding." 40 STUDY OF DIAGNOSIS. purpose feeling them until we can recognize them as well in the dark as in the light. We take the bones of the skeleton, and learn to re- cognize them by the touch as well as by the sight. Our Profs. Freeman or Howe will tell you the bones as well by touch as by sight. We take the dead body, and train the touch to recognize every part, by its form and resistance. We take the living body, and learn to re- cognize the impressions given by the skin, fasciae, mus- cles, bones, and by the cavities of the body. Attention has already been called to the necessity of the skilled touch in the obstetric art. You know a ver- tex presentation by the impression made upon the fin- gers brought in contact with the head. You determine fontanelles and sutures in the same way, and thus know the position. The nates give a different impression, and the finger recognizes the genitalia of male and female, as additional evidence. It recognizes a shoulder or elbow, a hand, a knee, or foot. How? Not intui- tively ; we have no natural knowledge of this kind, it is cultivated. Shall we wait until in obstetric practice we learn and acquire a skilled touch ? That would be very bad policy, especially for our patients. The sense of touch is first trained by general use, and then we find opportunity upon the child already born, to acquire the knowledge of how a cranium, suture, fontanelle, nates, genitalia, shoulder, elbow, hand, knee, foot, feels — it is easy enough to find the opportunity, if one is inclined to learn, and it is easy to get this necessary skill in obstetric diagnosis if one is inclined to improve his opportunities. Sight. — The sense of sight is one of the most impor- tant in diagnosis, and it, like others, requires education, STUDY OF DIAGNOSIS. 41 both as to the eye which receives and the brain upon which impressions are made. The eye receives im- pressions of color, and by education learns to detect the form, size, distance, and many of the physical prop- erties of objects. Color being one of the .prominent characteristics of health and disease, the ability to accurately distinguish colors must be a great aid to the physician. The un- educated eye receives the impress of color very much as it does light and shade, attaching about the same meaning to it, but when trained by use, it readily de- tects slight variations. It is quite easy to form a cabinet of colors, from natural objects which may be studied in detail, and this is suggested to the reader in preference to giving the color sheets here as first intended. The vegetable and insect worlds furnish them in great abundance, and specimens can be readily preserved. Quite soon the eye has learned to distinguish color from light and shade, and in a few weeks will become quite skilled, and yield much pleasure by the habit of observation thus acquired. There is nothing trivial in nature, and nothing so poor or worthless that it should not be known ; this is especially true to the physician because he must be a student of nature, to be able to deal with nature's greatest work, the human life. The practical education of the eye to color is com- pleted upon the human body. We find distinct varie- ties of color in health — of skin, of mucous membranes, of parts where the circulation is superficial, showing arterial blood, of veins, of the eye, the nails and the hair. We want to learn to know the healthy man by his color, and we may know him by this. 4 42 STUDY OF DIAGNOSIS. There is also abundant opportunity to educate the eye to the variations of color in disease, so that they will be readily recognized, and their true meaning known. We may procure types of these morbid colors, so that we will be enabled to refresh the memory with them. Some of these will be given farther along in this work, but the reader is advised to select samples of other colors for himself. The training the eye to the determining of size is not so important, yet will be found quite useful. One phy- sician will recognize a swelling, which evidences local disease, which another has failed to notice. So one will recognize a fullness of skin, of cellular tissue, of mucous membrane, of tongue, which another fails to see. Training the eye to recognize form is very important, both to the physician and surgeon. The trained eye of the surgeon at once detects a deformity, and deter- mines its cause, whether from fracture, dislocation, or structural disease. The trained eye of the physician should be able to recognize at once the general form of health, in the posture and expression of the patient, and the evidences of disease in the changes of form, in position, in sitting, lying, in the position of the limbs, and in the expression of the features. The trained eye recognizes changes in the form of the tongue, which express conditions of disease, and call for special reme- dies. Hearing.— Physicians do not seem to have realized the importance of the ear in diagnosis. It is true that we have a system of physical diagnosis for diseases of the chest, which the student is advised to learn ; but, STUDY OF DIAGNOSIS. 43 unfortunately, the advice is not supplemented by the lesson we are trying to teach — that these organs must be educated'. The student applies his untrained ear, and hears nothing, or is unable to distinguish variations in sound, and becoming disgusted, gives physical diag- nosis over to the expert or the specialist. Even if he persists in trying to learn, he finds that he can not hear the sounds described in the books, (simply because there are no such sounds produced),, and is thus discouraged. All nature is vocal with sound, and the sounds are the expressions of life. The old Hebrew poet recog- nized this fact, and gives expression to it — even " the morning stars sang together." All nature is vocal with sound, but to the uneducated ear it might quite as well be still, for it expresses naught to him. Train the ear, and educate the brain, and we have a " concourse of sweet sounds," taking the entire range of life, express- ing all its feelings, its hopes, its fears, its griefs, its cares, its pleasures, its pains. It recognizes the love song of the bird, the tone of wedded bliss, the gush of parental affection, the cry for assistance, the shriller cry of assault, the song of victory, the wail of defeat, and the moan of death. There is a fascination in the study of sound when once commenced, that will carry the observer on, and he will find a continued reward from it. If we take up the single study of the expression of animals in their cry, we find it of wonderful interest. We learn to re- cognize the speech of bird and beast, though we may not have slept with the fairies, as did the little boy of old. The cry of pain in the animal kingdom is so ex- pressive, that it will be recognized at once, and pretty soon we will find ourselves locating and giving charac- 44 STUDY OF DIAGNOSIS. ter to the disease by this expression. One of the most striking examples of this I have ever witnessed, was in the case of a pet goat that was poisoned by eating paint. The cry was as expressive as that of a child, and one involuntarily located the wrong in the intes- tinal canal — it was lead colic. " Ears ye have but ye hear not/' is applicable to the physician in ordinary. He is diligent in questioning the sick, and seems to think there is wisdom in the thoughts of the poor sick brain. The expressions of the voice, which tell the condition of the brain, and of the life of the man, to a considerable extent, is never heard, the doctor is deaf. In auscultation, the first lesson is in learning to hear. It requires close and continued study to hear the respi- ratory murmur distinctly, and this study must be con- tinued if we expect to recognize the variations of this and the sounds produced in the bronchial tubes. Skill in physical diagnosis does not come by nature ; it is the result of study, and the education of the ear and brain. No man can expect to succeed in it unless he is willing to give months to it, first to educate the ear to the hear- ing and analysis of sound, and next to the hearing and analysis of the sounds heard in the chest. Smell.— Of still less importance is the sense of smell, and yet it has its place in diagnosis. A good nose is a good thing, and the sense of olfaction should not only be a safeguard to the individual, warning him of noxious influences, but should be a source of pleasure as well. To some extent this sense is instinctive, especially as it warns against irritant substances, and leads to their avoidance. But it is one that may be educated to a STUDY OF DIAGNOSIS. 45 very high degree. We have examples of this in some varieties of merchandising. The wine merchant grades his wine by its boquet, as well as the taste. The tea dealer will classify his wares, and price them, by their odor, as will the fancy grocer with a majority of the edibles he deals in. We want a good nose for the purposes of diagnosis, and we especially want a good nose that it may look after the hygienic surroundings of our patients. There is an abundance of bad smells about the sick room, some peculiar to the condition of disease, and some the result of want of cleanliness and ventilation. We want to know them, and to do so we require an educated nose. What is an educated nose? It is one so trained by use that it transmits sensations to the brain, which has also been trained b}^ use to receive and analyze them. In other words, it is the association of brain and nose in the work. This sense is educated in the same manner as the others. We find odorous objects, and use this sense in their cognition. Pursuing the study we learn to discriminate between odors, and to recognize them immediately, and the character or condition of bodies they express. It will require but little training to enable this sense to detect the unpleasant surroundings of a patient. The first impression of the air of the sick room tells of a want of ventilation, of a deficient supply of oxygen, a superabundance of carbonic acid gas, and a surplus of foul gases. The nose not only recognizes these wrongs, but will insist upon their abatement. It says, open the windows and doors, let in the sunlight, build an open fire, and wash up. There is no mistaking the language, 46 STUDY OF DIAGNOSIS. and the physician feels that he must carry out its orders. It recognizes a want of bathing upon the part of the patient, dirty clothing, dirty bed-clothes, a foul chamber utensil under the bed, dirty dressings, dirty or bad food, dirty medicines, and says in unmistakable lan- guage, get these things away. u Cleanliness is next to godliness,'' and of far more importance in the recovery of the sick. It will also point out conditions of disease, and talk to you of special medicines. It says, typhoid, sepsis, loss of life and breaking down of tissue plainly ; and sug- gests for your consideration an individual of the group antiseptic — chlorate of potash, sulphite of soda, sul- phurous acid, carbolic acid, baptisia, permanganate of potash, etc. Taste. — Whilst the sense of taste is a good thing, and should be well cared for, we do not propose to make much use of it in medicine. It is well, however, to use it upon the food prepared for the sick, because we find a great many w^rongs here. Peopie have not lost the old impression that the sick need no food, and that it makes but little difference what kind is given, or how it is prepared. If the physician does not look after this, he will find many times that his patient is being starved because food is unpalatable, or so badly prepared that it is indigestible, or so changed in char- acter, that it really does the patient a wrong. If the physician has a right appreciation of the ne- cessity of good food, and the nurse or friends know that he will make it his business to look after it, and see that it is well prepared, they will probably use STUDY OF DIAGNOSIS. 47 more care, and will ask for information when it is re- quired. There are some things that the physician will do well not to cultivate a taste for or in. He should not be a connoisseur in liquors. It is far better that the patient run the risk of getting bad whisky, brand}', or wine, than that his medical attendant should have acquired the ability to determine for him. If there is any one road shorter than another to want of success, loss of character, poverty and wretchedness, it is the habit of tippling. The road seems especially broad, smooth and direct to the doctor, and he may well apply the old Latin quotation from Virgil : u Facilis descensus Averni" ; and the second line — " but to escape is indeed a work of difficulty." We have thus briefly examined the means by which one is prepared for the practice of medicine. The reader will have noticed that we place great stress on self-education, as the basis of skilled diagnosis and therapeutics. All knowledge is available in medicine, and we do not wish to depreciate the ordinary medical course of study, and would advise that the study of medicine and the collateral sciences should be carried as far as possible — and it is possible, even with the busiest man, to make very considerable attainments outside, as well as inside the range of studies usually pursued. Still, unless the physical organism be trained to use, our other education will prove a dead letter. It is the means that brings man in relationship to, and gives him cognizance of his surroundings and the world at large. He not only has knowledge of things through his senses, but his practical knowledge is in proportion to their education and acuteness. 48 STUDY OF DIAGNOSIS. In the study of disease it will be best to change the order in "which we have noticed them here. The phy- sician sees his patient first, and then the examination commences with the sight, touch, hearing, smell, taste. This may be regarded as the natural order, and we will observe it in the further study of the subject. THE USB OP THE SENSES IN THE DIAG- NOSIS OP DISEASE. It is well to notice that we have a two-fold object in studying. We wish to determine the locality and nature of disease — its pathology ; but we also wish to determine those agencies which will oppose disease and restore health — its therapeutics. These are both im- portant studies, and we do not wish to neglect either, yet the reader will see that the last is the practical one, If we can determine what will cure, we have accom- plished the important object of medicine. The means of cure have held a secondary place m medicine, and indeed it seemed sometimes that it held no place. Physicians would be very learned as to pathology, and able to divide and subdivide the lesions of function and structure until they would be " an im- mense multitude," yet you could count their remedies upon your fingers, and these were of the olden time, devitalising, and most absurd. You would find an im- mense volume on pathology and diagnosis, teeming with wisdom, and a therapeutics meager and feeble in everything but its power to do harm. STUDY OF DIAGNOSIS. 49 In this study we wish to make therapeutics occupy the first place, and the diagnosis will mean remedies, whenever this is possible. We do not care so much to affix a name, by which the wrong may be known, as to prefix a remedy by the means of which the disease will not be known. Or to put it in plainer form 7 the object of examination is to determine what will cure. It is my opinion that we can so study disease, that its symptoms or expressions will talk to us of individual remedies, and in language so plain that it can not bo misunderstood. As this is the first object of study, we will keep it constantly in view. DIAGNOSIS BY THE BYE. The educated eye requires no prompting to do its work in the examination of the sick — its training is to this end. It takes in the appearance of the patient and his surroundings in all their detail. An effort of the will is required to make the mind attentive, and to co- ordinate the impressions, and reach conclusions from them. It would seem unnecessary to say that many conditions of disease find outward expression through the muscu- lar system and its investing connective tissue and skin, and that the physician should recognize them as soon as his eyes have made their examination, and yet the study of medicine is pursued as if this were not so. The doctor is very eager to see the patient's tongue and feel his pulse, and ask all manner of questions pertinent and absurd, but he is blind to these natural expressions, or if he learns, it is slowly and because the facts are 5 50 STUDY OF DIAGNOSE. forced upon his consciousness. The reason is obvious — his attention has never been directed to it, and he has failed to study the subject as it was presented to him in practice. This study requires an exercise of the mind, and that the reader may commence thinking to advantage, we will take some very familiar examples in the animal kingdom. Let us see, for a moment, how animals ex- press emotion (the action of the mind in so far as it is developed). If you notice your dog or cat for a few days, you will see the clear expression of the entire range of the emotions, anger, fear, love, hate, joy, grief, consideration, conclusions reached, etc., and so plainly that you can make no mistake. Examine your horse, and you will find the same clear and striking language of expression. It is really wonderful, this voiceless language of animal life, and well repays study. Supposing now we study the expression with refer- ence to rest. You notice the dog taking his siesta, and carefully scan his posture and feature, and the idea of rest is so strongly impressed that you are sure you could not be mistaken. Whistle sharply, and notice the change to a position and expression of activity and ex- pectant attention. Give his ear a sharp pinch, and you will sec the evidences of pain as clearly as you would in the expression of man. Think of the sickness you have seen among animals. The cat or dog with a " sick stomach " — before they have made an effort at vomiting you have jumped for the door to let them out. In ordinary ailments the drooping head, ears and tail, the expressionless eyes and face, and indeed the entire want of muscular ex- pression, tells the story of impairment of life. Take STUDY OF DIAGNOSIS. 51 an irritative disease, of the intestines for instance, and the marked contraction of muscular tissue; the rough- ened coat, the strong drawn lines of the face, the re- tracted lips, tell you the kind of wrong. Would you know if your horse was sick by his ex- pression f I think you would, and if the subject had a little study you would know the kind of sickness as well. If you found him in the morning with drooping ears and tail, expressionless eyes and nose, you would hardly take him out for a day's ride. You recognize the expression of exhaustion from over-work, and feel so much for your companion that the stable is visited before retiring, and you probably know from his pos- ture and expression in the stall whether he is resting, or in a condition that precludes rest. If in driving you notice the ears drooping or turned backward continuously, you know there is something wrong. That the one means a wrong of exhaustion, and the other a wrong of irritation. If you notice his tail fall helplessly between his legs, you feel sure he is in no condition for work, is suffering from exhaustion. Suppose you observe an unnatural twist in his tail to one side, and you are quite as sure he is sick, the dis- ease one of irritation, probably colic. Carry this observation a little further, and watch the process of labor in animals, and you will be still more surprised at the wonderful mechanism of voiceless ex- pression. You will be able to read the history as plainly as if expressed in language. The process of dilatation, the expulsive second stage, the tedious and difficult labor, the irregular and inefficient uterine contractions, the rigid soft parts, etc. Let us watch the case of a cow with puerperal fever, (yes, she has puerperal fever, 52 STUDY 01 DIAGNOSIS, and other puerperal diseases as has the human mother), and you will Bee every phase of Buffering, ami Bee it so distinctly that you can not forget it if you would. Yon notice a horse put out one of his feet in stand- ing, ami at oiuv you think of disease. By the expres- sion of the leg and its position, your accomplished horseman will loeate the wrong tor you : telling you Whether it is in the shoulder, leg, knee, in the lower articulations, or in the hoot'. How does he tell? Be- eanse the leg has a language, and he has learned it. I have eited these examples as subjects of thought. This study requires thought, and the doctor is so little in the habit of right thinking with reference to human disease and diagnosis, and so certain that everything must be known, that it is better to get a basis for thought outside. If the reader recognises the truth of these statements, and can confirm them by observation, he will say at once — ' v if disease is thus clearly ex- pressed in the lower animals, there must be similar ex- pressions in man, and the subject is well worth my attention." Disease has a voiceless language, and it is this we wish to study, but in order to do so successfully, the reader must get a basis for thought, commence to think of it, and find his illustrations in every-day life. It is well to have clearly before us at the commence- ment, the objects of the examination, and the faets that may be determined ; they may be classified as follows: l>t. The right life that we designate as health ; 2d. The wrong of life that we call disease — the amount of vital impairment; 3d. The condition of rest : 4th. The con- dition of unrest : 5th. Disease of excitation ; 6th, Dis- ease of depression ; 7th. Pain ; 8th, The evidence of local disease, both as to structures involved, and kind. STUDY OF DIAGNOSIS. 53 Decumbence. — In acute disease, the impairment of life is usually such that the patient assumes and keeps a horizontal position, as this requirestheexpenditureof much less power than any other. We use the term de- cumbence in preference to the old medical one, decubi- tus, and it is defined by Worcester as " The act, or the posture of lying down, prostration." In health the de- cumbent position is associated with the idea of rest, and when assumed at unusual times, with the idea of debility. Thus the first idea obtained from seeing the patient in bed is, that there is impairment of life. It would be a blessing to the sick if the physician could get this fact so thoroughly impressed, that he would re- fuse to depress the life still more by the administration of drugs. Evidently this fact is one of much importance, and whilst the general expression may not be absolute evi- dence, it is among the best we have. If in acute dis- ease the patient keeps his bed all the time, there is con- siderable impairment of life. If in ordinary chronic disease we find the patient frequently assuming the de- cumbent position, and maintaining it for a considerable time, we have to consider it an evidence of enfeeble- ment, and we husband our patient's strength, and em- ploy the class of remedies known as restorative, with appropriate food. Studying the patient's expression in bed, we find that it gives us additional information. If he lies on his sides, changes his position readily, holds his shoulders and extremities in position, we conclude that the im- pairment is not great as yet. But if we see him in- clined to lie upon the back, or if upon the side that the shoulder falls forward or down, the arm falls and is 5± STUDY OF DIAGNOSIS. expressionless, the upper leg and hip show the inclina- tion to fall, and even the soft tissues of the face droop, we are certain there is great impairment of life, and the treatment must be conservative and restorative. In the worst case, where the patient lies continuously upon his back, and is inclined to slip toward the foot of the bed, physicians usually recognize the approach of death. There can be no mistake about the importance of the inquiry, or the character and certainty of these expres- sions. If we know that the life is feeble, we will care- fully husband it, and guard against unnecessary expen- diture. If we know the life is feeble, we will be sure to avoid unpleasant and harsh medicines, especially the class antiphlogistic. If we know the life is feeble, we will appreciate the im])ortance of keeping the digestive organs in good condition, and giving the necessary food. If we know the life is feeble, and we have any- thing in our Materia Medica that will aid and strengthen it, we will realize the importance of its use. To determine the condition of rest or unrest is of great importance. When a man or a part is sick, rest is necessary to recovery, and very much of the treat- ment used looks to procuring rest. The position of de- cumbence is assumed to get rest, yet we find that many times it is not sufficient. It is well to know that we have to think of this with reference to sleep as when awake, for though sleep usually means rest in health, it may not give rest in disease. It is well to get an idea of perfect rest in health, as a standard of comparison. Observe the child sleeping, and the perfect equipoise of the entire muscular system, and the natural position of the extremities show the condition of rest. Even when the child falls asleep in STUDY OF DIAGNOSIS. . 55 a constrained and unnatural position, the body so adapts itself to it, that we have the idea of rest. A group of harvest workmen, taking their noonday rest on the grass under the shade of a tree, will give every shade of this restful expression, and is well worth our study. We learn something here that can not be told in words, but which serves as an excellent standard of comparison at the sick bed. Notice the position of a healthy person in sleep, especially how the body accom- modates itself to bed and pillows, so that one position will sometimes be maintained the whole night, with rest to every part. Now when we come to examine the sick, the condi- tion of unrest is clearly expressed. The body does not accommodate itself to the bed, and the effort to main- tain the position shows itself in the constraint of dif- ferent parts. We see it in the evident contraction of the cervical muscles to hold the head in position ; in the unnatural flexure of the extremities to maintain the body and themselves in position. AVe have every gradation of these expressions, from that which comes some time after the position of the body has been moved, when the patient is tired, to that which is so continuously marked, that we know the patient has not one moment's rest. The position of the body also tells us something with reference to the fifth and sixth propositions — whether the disease is one of excitation or depression, especially as regards the circulation. This also is an important element in diagnosis, and refers us to appropriate reme- dies. The condition of excitation is marked by constraint and undue contraction. We notice it in the expression 56 study oe Diagnosis. of the entire person, and of special parts. In the first it has reference to the entire body, in the second it is more the expression of local disease. The ideas that we get is of want of ease, and of constant effort on the part of the muscular S3 T stem to obtain it. An unusual and constrained position of one or more of the extremi- ties is quite a common expression. It may be but flexure of one leg, throwing it out or from the body, or a contraction and elevation of one shoulder, or a prone fore-arm and hand with marked muscular contraction, or an unpleasant constrained position of the head, with prominence of the cervical muscles, or we may have it in facial expression. Once the mind is directed to it, these features are quickly learned, and having the knowledge of health, we quickly determine the extent of the lesion. The evidences of enfeebled function — depression, are just the opposite. Whilst in the previous case, we have an unusual excitement of the nerves, and of the vascu- lar S3 T stems, in this we have deficient innervation, and impaired circulation. In this there is want of expres- sion, the body lies, so to speak, as if no effort was made to hold it in position ; parts fall of their own weight. This want of expression is noticed especially in the subcutaneous muscles, and in the skin, giving an un- pleasant uniformity of surface, and a sodden expression to the soft tissues. Pain, or suffering, is expressed in every portion of the body, and one may learn to recognize it as soon as the eyes strike the body, and yet it would be difficult to describe the expression. When pain is associated with, or the result of undue excitation, the expression will be that just named under this head. But if asso- STUDY OF DIAGNOSIS. 57 ciated with, or the result of an enfeebled condition, either of the entire body, the part suffering, or the brain, the general expression may be quite the reverse, and will more resemble the exhaustion that follows ex- cessive grief — one of anguish. As has been clearly shown by Darwin ,* expression is most marked in those muscles in most common use, or those associated with mental activity. Thus we would *Ihave now described, to the best of my ability, the chief ex- pressive actions in man, and in some few of the lower animals. I have also attempted to explain the origin or development of these actions through the three principles given in the first chap- ter. The first of these principles is, that movements which are serviceable in gratifying some desire, or in relieving some sensa- tion, if often repeated, become so habitual that they are per- formed, whether or not of any service, whenever the same desire or sensation is felt, even in a very weak degree. Our second principle is that of antithesis. The habit of volun- tarily performing opposite movements under opposite impulses has become firmly established in us by the practice of our whole lives. Hence, if certain actions have been regularly performed, in accordance with our first principle, under a certain frame of mind, there will be a strong and involuntary tendency to the performance of directly opposite actions, whether or not these are of any use, under the excitement of an opposite frame of mind. Our third principle is the direct action of the excited nervous system on the bod}-, independently of the will, and independently, in large part, of habit. Experience shows that nerve-force is generated and set free whenever the cerebro-spinal system is ex- cited. The direction which this nerve-force follows is necessarily determined by the lines of connection between the nerve-cells, with each other and with various parts of the body. But the direction is likewise much influenced by habit; inasmuch as nerve-force passes readily along accustomed channels. 58 STUDY OF DIAGNOSIS. expect to find the most marked expression in the face, and next probably in the hands and the extremities. If the reader will think for a moment, he will probably recall distinct expressions in these forms. He will especially recollect the common expressions of pain in the muscles of the orbits and frontal region from con- traction of the corru gator supercilii, some of the fibres of the occipito frontalis, the orbieulars, and sometimes the zygomatic. His attention will only need be called to the forced contraction of the flexors of the hand during labor, the involuntary expression of pain, and to similar contraction in the feet. Indeed here is a most excellent sfoKiy. and one may learn the natural history of pain by closely observing a few labors. There is nothing like having a familiar example for study, and we may look still further at the phenomena of childbirth. I need hardly say that these expressions have the same meaning as in ordinary disease, though here we find them greatly intensified. Possibly we will get as good an idea of rest during the absence of pain in a natural labor, as we can get anj T where. And in a difficult labor we will get as distinct an idea of the state of unrest. We observe the pain, finding expression in marked muscular contraction of the muscles of the upper and lower extremities and the forced flexion of the muscles of the hands and feet. We also see the ex- pression of pain in the countenance, but in natural labors it is evanescent and not very marked. In diffi- cult labors, especially where the pains are inefficient, we find the constant contraction of the " muscles of pain/' and it is one of the evidences of this condition. The evidence of local disease will be found in the po- sition of the body with reference to removing pressure STUDY OF DIAGNOSIS. 59 from the part, or giving it support. This is sometimes so distinct that the attention is at once directed to the affected part. Ii the position of the body is such as to take off muscular pressure, we conclude that the disease is one of excitation. If, on the contrary, the position is such as to give additional support, we would think of it as being one of impaired innervation and circulation, possibly congestion. A man gives a diseased leg rest in the same manner as a horse. Flexion takes off ten- sion, and if the disease is one of irritation, the limb is flexed. Disease of bladder or rectum will be indicated by flexure and crossing of one thigh over the other. Disease of the abdominal viscera, by flexion of the thighs upon the trunk and probably flexion of the trunk. Disease of one kidney will be announced by flexion of the body on the affected side. Disease of stomach by marked flexion of the trunk, and relaxation of the ab- dominal muscles and diaphragm, and thoracic respira- tion. Disease of one lung will be indicated by the flexion of the body on the affected side, and the droop- ing of that shoulder. Disease of the upper lobe of the lungs will be indicated by the falling of the shoulders forward, the additional curvature in the upper dorsal and cervical spine, and by abdominal respiration. A very natural expression of disease is the involun- tary movement of the hand to it. In typhoid fever, when the patient is seemingly wholly unconscious, we find the hand over the bladder in retention of urine, as it seeks the umbilicus when disease of Peyer's patches is marked. The child suffering from disease of the ear involuntarily carries the hand to the affected part. In acute disease of the kidneys the hands are carried to the loins. In some gastrointestinal disease the hands 60 STUDY OF DIAGNOSIS. sometimes go to the mouth, and it seems as if the child wanted to get something out of its throat. It is always well in low forms of disease to carefully watch these expressions, as they give us early intimations of local trouble. And in diseases of children, when we have to depend almost wholly upon our own observation, it is also well to carefully observe every expression. Facial Expression. — The fact has already been no- ticed that mental states find easiest expression in the usual channels of innervation, and through those mus- cles in common use. This is not only true of mental activity, but is also true of disease. There is no disease without a wrong of the nervous system, and I think I may add with truth, that there is no wrong of life that is not represented upon the surface through the nervous system. We may not be able to read it, because our senses have not been trained to observation, and we have not sufficient experience, but the fact that disease is thus expressed should stimulate to study. The face will show clearly the right life that we call health ; and the wrong life we call disease. If one will closely study the expression of the face in health, and compare it with the expression seen in sickness, this fact will be clearly seen. It not only tells us of im- paired life, but also of the kind of impairment, and of the remedies that will remove the wrong, and restore health. It will be w r ell to make this study with refer- ence to — 1st. The condition of the brain ; 2d. With reference to the condition of the sympathetic nervous system, and associated spinal cord; 3d. With reference to the condition of the circulation and the blood ; 4th. With reference to local disease; 5th. With reference to pain ; 6th. Resistance of disease. STUDY OF DIAGNOSIS. 61 The Condition of the Brain is very clearly ex- pressed in the face, and we have learned quite a good deal of its language. We may subdivide this study into — a. With reference to the circulation, determiuation of blood, congestion, inflammation, effusion ; b. The nu- trition of the brain ; c. Its functional activity. Determination of Blood is marked by flushed faca, bright eyes, contracted pupils, and general but moderate contraction of the facial muscles. The expression is one of excitation, and the patient is restless and uneasy. The direct remedy is Gelseminum. The indirect means are those which relieve vascular excitement, and the old-fashioned derivatives— counter-irritation, etc.* Congestion is marked by dull eyes, dilated pupils, immobile pupils, expressionless face, patient dull, in- clined to sleep, and eventually coma. *A bright and sparkling eye is as characteristic of a pleased or amused state of mind, as is the retraction of the corners of the mouth and upper lip with the wrinkles thus produced. Even the eyes of microcephalous idiots, who are so degraded that they never learn to speak, brighten slightly when they are pleased. Under extreme laughter the eyes are too much suffused with tears to sparkle; but the moisture squeezed out of the glands during moderate laughter or smiling may aid in giving them lustre; though this must be of altogether subordinate importance, as they become dull from grief, though they are then often moist. Their brightness seems to be chiefly due to their tenseness, owing to the contraction of the orbicular muscles and to the pressure of the raised cheeks. But, according to Dr. Piderit, who has discussed this point more fully than any other writer, the tenseness may be largely attributed to the eyeballs becoming filled with blood and other fluids, from the acceleration of the circulation, consequent on the excitement of pleasure. He remarks on the contrast in the appearance of the eyes of a hectic patient with a rapid cir- 62 STUDY OF DIAGNOSIS. The direct remedy is Belladonna. In some cases, and when associated with local disease with impairment of the involuntary muscles, Ergot The indirect means are counter-irritation, dry or wet cupping, stimulant cathartics. An intermediate hypercemia, observed in apoplectic conditions is marked by fullness of eyes, which are protruded, fullness of face, prominent veins, and from contraction of the platysma a drawing down of the face and angles of the mouth. For this condition the direct remedies would be Ergot, Lobelia in stimulant doses, Apocynum. The in- direct remedies, dry or wet cupping, stimulant hydra- gogue cathartics. Inflammation is marked by still greater contraction of the muscles, especially those of the orbits and the frontal region, the deeper flushing of the face, the sharper expression of the eyes, which are dry and pinched, the contracted pupils, and as the life is im- paired, by the appearance of constriction of all the tis- sues around the base of the brain. The direct remedies in the first stage of an inflamma- tion of the brain are : The proper sedatives, Aconite or Veratrum, and Gel semi num. These may be followed and aided by such as increase the action from skin, kid- neys and bowels. The indirect remedies are such as may call the excitation to other parts. culntion, and of a man suffering from cholera with almost all the fluids of his body drained from him. Any cause which lowers the circulation deadens the eye. I remember seeing a man utterly prostrated by prolonged and severe exertion during a very hot day, and a bystander compared his eyes to those of a boiled codfish. — Darwin. STUDY OF DIAGNOSIS. 63 Effusion is marked by the dullness, and finally by coma. The eyes lose their sharp, bright expression and become dull ; the muscles of the lower part of the face relax, as do the muscles that move the inferior maxillary and the mastoid. If the irritation still continues, the contraction of the orbiculars and frontal muscles per- sists, and the evident constriction or pinched appearance around the base of the brain becomes more prominent. If the irritation passes away with the effusion, these muscles gradually lose their power, and the upper part of the face assumes a dull, sodden appearance. The direct remedies are small doses of Aconite and Belladonna, alternated with Apocynum. The indirect means will consist in cupping the spine, and the use of a stimulant hydragogue cathartic. The Nutrition of the brain is not so easily deter- mined, yet I think we may reach correct conclusions in the majority of cases. The enfeebled nutrition will be marked by a want of expression, especially in the mouth, showing a want of decision. The eyes may have a normal appearance at first sight, yet as we watch them uncertainty is shown in their movements. In some cases, the expression when the patient's attention is not attracted, is very like that which follows exhaustion from excessive emotion. Softening of the Brain, so called, will be marked by a smooth, placid countenance, the want of expres- sion in the forehead being especially marked. In some of these cases the tissues have their ordinary fullness, and sometimes the soft tissues of the face are unusually full, yet they look soft and flabby, and hang in un- natural folds. Atrophic Irritation of the Brain is marked by 64 STUDY OF DIAGNOSIS. the pinched and uneasy expression of the upper facial muscles, the muscles of the orbits and the frontal region. The patient holds his head in a constrained position, frequently inclined to one shoulder, and the face turned to one side, giving the eyes an unpleasant expression of obliquit}^. The elevation of one eyebrow and the fall- ing of the other, with an apparent divergence in the axis of the eyes, will locate the lesion in or near the cerebellum. The evidences of structural disease vary with the situ- ation and character of the lesion. They may be divided into irritative and atonic, the one showing marked contraction of some muscle or muscles of ex- pression, the other a want of contraction, and conse- quent fullness and drooping. Sometimes in the severest structural disease there is no external expression. The Functional Activity is very clearly shown in facial expression, and we will observe the entire range from normal function to furious delirium on the one hand, and to entire loss of function and conscious life on the other. Activity is not only shown in muscular contraction, but in alternate contraction — the play of the emotions — of the muscles. This change of expression is one of the most familiar examples of mental activity. In de- lirium we observe that the play of the muscles is exag- gerated, as indeed is the expression of all the emotions. This is especially noticeable in the expression and movement of the eyes, and their external muscles. Want of Activity is expressed by want of contrac- tion of the facial muscles; dull, immobile eyes, and full lids. The condition of the sympathetic nervous system is STUDY OF DIAGNOSIS. 65 pretty clearly shown by the eyes, the orbital muscles, and the tissues about the base of the brain. The disease of irritation is shown by the contraction of the tissues which form the bed of the eye, the retraction of the eye, especially upward, the thinned and constricted eyelids, and the tissues about the temples. In some cases the pinched or contracted alae nasi is a marked feature. The disease of atony is shown by the full, ex- pressionless eyes, fullness of the lids, pallid and waving alae nasi, and fullness and want of expression about the mouth. A temporary want of sympathetic innervation that is rectified by Podophyllin, is shown in the fullness of all the tissues of the face, especially the ujyper portion, and by fullness of the veins. For the disease of irritation, 1 prefer Aconite, Ehus, B^onia, Muriatic Acid, Nitric Acid, the selection being made by the other symptoms present. Temporary re- lief is obtained by the local application of Chloroform before and behind the ears, and over the first cervical ganglion. The Chloroform is so applied as to prevent evaporation, and a change in the pulse will usually be noticed in a few minutes from its first application, and the relief is marked, and very frequently it lasts for some time. The disease of atony is met by Nux, Phosphorus, Quinine, stimulant doses of Lobelia, minute doses of Podophyllin, Digitalis, more rarely Veratrum, the bitter tonics and food. Whilst the expression of the face will give us pretty accurate information with regard to the circulation, we may obtain this information more directly elsewhere. If the cellular tissue is full, we think of Veratrum. If 6 66 STUDY OF DIAGNOSIS. it is shrunken, Aconite. If the expression of the eyes and associate muscles is dull, with fullness, we think of capillary congestion, and Belladonna. If the cellular tissue is full, the face expressionless, and the veins prominent, Podophyllin. If the eyelids are especially full, Apocynum. If the eyes have a pinched expres- sion, dry in acute disease, secretion of tears in absence of fever, dry, shriveled epidermis, flushed left cheek, Elms Toxicodendron. Eight eyebrow drawn down, and expression of eye changed, flushed right cheek, Bryonia. These are the most prominent examples, and in each case there is a wrong of the circulation, which may be the predominant wrong. At any rate, the remedies thus indicated will prove curative. With reference to the condition of the blood, we may find more direct expressions than in the face, yet these are not unimportant. The sodden tissue evidences poor blood and poor nutrition, as the firm elastic tissues show good blood and good nutrition. The typhoid con- dition of the blood will be clearly shown in the con- tracted and opaque skin in the one case, and the sodden inelastic tissues in the other. Pyaemia will show itself first, in the marked contraction of tissue about the base of the brain, sinking in of the bed of the eyes, and espe- cially by retraction in the upper part of the orbit. Some local diseases are clearly indicated by facial ex- pression. Disease of the respiratory apparatus will be shown by the expression of the nose and accessory muscles. The lesions of irritation by contraction, the lesions of atony by relaxation. Any one who has watched the progress of an acute inflammation of lungs, of pleura, of bronchia, with irritative cough, must have seen the pinched expression of the nose, and the con- STUDY OF DIAGNOSIS. 67 traction of the alse. So marked is this, that sometimes it seems to precede the trouble, and will be marked, be- fore the disease of the respiratory apparatus has full development. The relaxed and waving aloe nasi gives an unpleasant impression of disease, and as before named, has reference to the lesion of innervation, as well as to impairment of the respiratory function. The expressions of the mouth are associated with dis- ease of the abdominal and pelvic viscera. Let us take the familiar examples of intestinal worms as an illus- tration. The full upper lip, with pallor, the white lines arcund the mouth, and picking the nose, is the most pronounced evidence of ascaris lumbricoides This worm inhabits the small intestine, and the conditions present are atony of mucous membranes, with impaired function, and increased secretion of mucus, and at once we think of the associated symptoms and the intestinal wrong. The remedies will be those which will give normal stimulation to the structures involved, Podophyllin, Santonine, some of the ordinary cathartics, the sto- machic bitters, and sometimes the alkaline salts, or acids, as may be indicated by other symptoms. If fullness in this case means atony and impaired function, and increased mucous secretion, it must mean it always, and we will always think of such remedies as will influence the small intestine and associate viscera, giving normal stimulation and circulation, and restoring functional activity. There is a peculiar expressionless mouth, or an expression of u loss of spirits/' with a little depression of the angles of the mouth, that invariably means Kux Vomica. Nausea is shown by depression of the angles of the 68 STUDY OF DIAGNOSIS. mouth, and slight incurving of the lower lip. If the tissues are full, we know that there is atony ; if pinched and shrunken, that there is irritation and determination of blood. It is a singular fact, and one not heretofore noticed, so far as my reading extends, that simulation of these expressions will provoke sensations in the parts referred to. The instance just given affords a marked example. Let a person draw down the angles of the mouth and incurve the lip, and he will be quite certain to feel nausea after a time. In two persons who tried it the sense of nausea was very marked ; in one producing vomiting, in the other an arrest of digestion and head- ache. Try to simulate the frontal expression of pain, and it will be singular if you do not wake up unpleasant sensations somewhere, perhaps real pain. Contraction of the orbicularis oris is usually found in some diseases of the reproductive organs, especially of the female. In chronic disease, there is distinct retrac- tion from the other muscles of the face, and the entire tissues seem thinned. In some of these cases the zygo- matic muscles are also prominent. Pain and Suffering are distinctly expressed in the features, yet not always in the same way. Firm con- traction of muscles is the most common expression. Thus every reader will recollect the contracted brow as evidencing pain, especially pain with irritation of the nerve centres. We involuntarily associate contraction of the structures about the eyes, and the wrinkled skin, with pain, or with suffering. But we have the evidence of pain in this region without muscular contraction ; indeed there is the reverse, drooping of the tissues, the expression is sad, of the exhaustion that follows exces- STUDY OF DIAGNOSIS 69 sive grief, and we are assured that there is enfeebled circulation in the brain, and the pain is the expression of atony. It is very important to make these distinctions in order to select remedies. Pain is the result of two very opposite conditions — an excited circulation and an en- feebled circulation. In the one case we use Gelsemi- num, the sedatives, salines, Ehus, Macrotys, Bryonia, as may be indicated. In the other we use Quinine, stimulant doses of Opium, JSTux, stimulants, tonics, beef tea or other histogenetic food. Pain in the abdomen, pelvis, or lower extremities, finds expression in the mouth. Acute pain almost always finds expression in contraction of the mouth ; when very severe the lips are firmly drawn in, the angles of the mouth retracted, and somewhat depressed. In some other cases, the angles of the mouth are drawn in, and there is that action of the muscles of the upper lip that gives it and the cheeks a full expression. I hardly need call attention to the fact, that some patients resist disease by an influence of the will, and that sometimes this effort is very important. Others yield to it from the first, and thus favor its progress. Every one has made these observations, and will recog- nize the importance of knowing whether a patient re- sists or yields, as it may determine whether he will re- cover or die. Darwin remarks that — " The firm closure of the mouth tends to give an expression of determination or decision to the countenance. No determined man probably ever had an habitually gaping mouth. Hence, also, a small and weak lower jaw, which seems to indi- cate that the mouth is not habitually and firmly closed, 70 STUDY OF DIAGNOSIS. is commonly thought to be characteristic of feebleness of character. A prolonged effort of body or mind im- plies previous determination ; and if it can be shown that the mouth is generally closed with firmness before and during a great and continued exertion of the mus- cular system, then, through the principle of association, the mouth would almost certainly be closed as soon as any determined resolution was taken." I do not think any one can make a mistake here, and certainly it is important to know whether the patient is inclined to resist disease, and is determined to get well, or whether he is yielding, despondent, hopeless. The firm mouth means that the patient will get well if he can. The relaxed, drooping mouth, falling jaw, trem- bling muscles, show us the need of giving the patient courage, and strengthening the will power. It also shows the necessity of increased care to conserve vital- ity, and of the employment of restorative remedies. Expression in Motion. — We not only find disease expressed in position, and in persistent muscular con- traction, as heretofore named, but it is also shown in motion. We see a man standing or sitting, and ob- serve that his soft tissues seem to sit on him like a badly fitting suit of clothes, and we think at once of impaired nutrition and degeneration of tissue. But it may be only a want of innervation, from habitual torpor of the nervous system. Set him in motion, and we will soon see whether this is so or not, for there are none so sluggish in this respect, but what they may be aroused. We notice the movements of the person that we may confirm the diagnosis of expression, especially as re- STUDY OF DIAGNOSIS. 71 gards the important point of undue irritation and cir- culation, or impaired innervation and circulation. The quick, restless movement is characteristic of the first. The desire to lie still, and the slow movements, of the second. Possibly there is no evidence of disease more definite than this, and it should be allowed its full weight in diagnosis. In some cases the rapid movement is but a means of removing excessive excitement of the brain and spinal cord, as in great grief or joy, or in case of severe, but temporary pain. In such cases it may be looked upon as a means of relief, for if the excessive emotions, or pain were pent up, the person might suffer severely from it. But in other cases, whilst i,t tells of nervous irrita- bility, the bodily movements give no relief, but even in- tensify the wrong, besides causing exhaustion. In these cases we endeavor to get bodily rest from the first, as a means of allaying the nervous excitation. Every one will have noticed the influence of the phy- sician, nurse, or iriend, who with kindness but firm- ness, insists on keeping still. The hand placed upon the body of the sufferer to give support, seems to strengthen the will power, and frequently with an effort on the part of the patient comes rest and relief. There is a case of restlessness from an enfeebled and atonic condition of the nerve centres that requires notice. The unsteady movement, or the evidence of exhaustion following it, with the anxious, depressed countenance, tells the story. In the other case we will find almost continued tension of the muscular system. Whilst in the case of irritation and determination of blood, we would employ the sedatives, with Gelseminum. 72 STUDY OF DIAGNOSIS. or remedies exerting a like influence, in that of atony, we would use Quinine, Nux, Phosphorus, stimulants, tonics, and histogenetic food — beef-tea. Increased movement is not associated with structural, or even with severe local functional disease, so that un- less it points to a wrong of the cerebro-spinal centers we do not regard it as an unpleasant symptom. In or- dinary colic the patient is restless, and seems to get re- lief from motion, but in the severer forms of colic, called " bilious," and in acute enteritis, he remains very still. In local disease the patient favors the affected part in movement. Frequently the first evidence we have of morbus coxarius, is the care shown in moving the leg and placing the feet in walking, and the elevation of the hip to remove pressure from the joint. Turning the toes inwards, both in movement and rest, has the same signification. One can readily distinguish a wrong of the pelvic viscera by the movement of the hips and extremities, showing the constant effort to prevent stress or pressure of the parts. This will be noticed in some uterine disease (irritative) as well as in displace- ments. In chronic disease of the kidneys, a forward curvature of the spine is frequently marked, and the patient is observed to put the hands upon the hips in rising from the chair, and sometimes in walking. If but one kidney is involved, or the liver, or spleen, we observe the slight flexure to one side, and the effort to save the part from the movement of muscles. Evi- dently the drawing forward of the shoulders — " winged scapula," is a symptom of similar import so far as the lungs or thoracic region is concerned. So certain is this, that with the marked falling forward of the STUDY OF DIAGNOSIS. 73 shoulders, and separation of the scapulae, one may be sure there is some disease in the thorax. The head drooped forward has a similar import, though this is sometimes an indication of a wrong of the sympathetic nervous system. In irritative disease of the cerebrum, or of the organs of special sense the head is flexed, but in disease of the medulla oblongata, cerebellum, pons and crura, the head is drawn backwards. Forced extension, or head drawn backward, will be recollected as a prominent symptom in cerebro-spinal meningitis. In all these cases flexion and favoring the part in muscular movement are evidences of irritative disease, and indicate the treatment. First, remedies that influ- ence the affected part ; and second, remedies that re- move excited innervation and circulation or functional activity. In another class of cases, we will find flexion from or opposite the affected part, and the position of the body, and muscular motion is such as to give support and moderate pressure. The evidence in this case is of im- paired circulation, congestion, effusion, and enlarge- ment. It is safe to say that in the majority of these cases the remedies w^ill be such as will give additional stimulus. If one will closely observe the movements of the ab- dominal muscles, they may determine conditions of dis- ease in pelvis or abdomen. The careful, slight move- ment evidences disease of the pelvic viscera if especially marked below — the chylopoietic viscera, if especially marked above. The full abdominal walls, with slug- gish movement, evidences atonic disease and congestion. If we examine with reference to the thorax, we will 7 74 STUDY OF DIAGNOSIS. find that free movement of the abdominal muscles and diaphragm, and but slight movement of the upper thorax, is evidence of disease of the upper lobes of the lungs. On the contrary, thoracic respiration, with but slight and careful movement of the abdominal muscles, evidences disease of stomach or liver. We have already examined the expression of the face sufficiently, and the movements of the muscles do not give much additional evidence. Twitching of the muscles is an unpleasant expression, and indicates un- due spinal irritation, or irritation of the basilar brain, the cause being frequently extrinsic. If of the mouth, our attention is directed to the abdominal organs ; if of the upper lip and face, to the stomach ; if of the nose, to the lungs ; and if of the eyes and forehead to the brain and spinal cord. The quick, involuntary movement of the eyes, refers us at once to the excito-motor nervous system, and at once we make an examination to determine the source of the lesion, its cause, and adopt means to prevent its further progress, and convulsions. The forced con- traction of one of the muscles of the eyeballs, turning them upwards, downwards, to one side, or causing stra- bismus, evidences disease of the brain, which may or may not be associated with wrong of the spinal cord. The character of the disease may be determined by the expression of the eyes and associate muscles, or by other symptoms. In diseases of children we will notice that sudden contraction of muscles and movement of parts is a pre- cursor of convulsions. The quick movement of the hand, with contraction of the fingers, the quick move- ment of the lower extremities, with forced flexion, or STUDY OF DIAGNOSIS. 75 the quick movement of the head upon the pillow, or the sharp, jerking movement of the shoulder, should never be neglected. This is but a mere outline of the subject, yet if it stimulates to observation, pointing out the way, it will serve its purpose. It is something one must learn from observation, and not simply store up in the memory. Indeed, unless the senses can be trained with the memory of facts, but little benefit will follow. COLOE OF THE SURFACE. As has already been named, the education of the eyes to distinguish colors, is of much importance in diag- nosis ; and the reasons will be obvious to the reader. There is no property of living bodies so sensitive as color. It is usually thought of as evanescent, change- able, fleeting, and the expressions of poetry in this re- gard, but represents the results of close observation. The florist is guided by it to a very considerable ex- tent. When he visits his green-houses in the morning, his eye closely scans the plants with reference to their health. Change of color, even so slight that it would not be noticed by an ordinary observer, is to him evi- dence of disease. He recognizes in change of color, the escape of gases from his flues, want of ventilation, a wrong in the temperature, the want of, or a wrong plant food, the presence of parasites, etc. He not only makes his " diagnosis " from change of color, but gives the prognosis as well. The farmer, without any special training, or knowing why, recognizes the wrong color in his plants, and 76 STUDY OF DIAGNOSIS. speaks of their sickly appearance. If he has been a close observer, there is a something about their expres- sion, and usually in their color, that tells him of the character of the wrong — from drouth, from wet, from too much heat, from cold, from atmospheric changes, from want of plant food, from excess of certain foods, or from a wrong kind. He recognizes the coming of blight, rust, mildew, and the various parasitic diseases, by these changes, before the diseases are fully de- veloped. These are familiar examples, and should prompt to diligent study on our part. For, if in the vegetable world, disease may be recognized in changes of color, should it not be a means of diagnosis in animals and man? And if so definite in determining the kind of disease in vegetable life, will it not be equally definite in determining disease in man? It will be noticed further that color has reference to the life ; to the life of the blood, to the nutrition of tissue, to the oxygenation and decarbonization of the blood, and to the waste and excretion. Even here the popular expression should have stimu- lated professional inquiry — he has a healthy color — what is the color of health ? he has a sickly appearance, what is a sickly color? If the popular mind recognizes health in color, and disease in color, is it not well that we should make a careful study of it ? Color in man has two sources — a, from the blood ; 6, from pigment — and it is well to distinguish these. In the first case the changes of color are referred to wrongs of the blood ; in the second they are referred to changes in the quantity or character of the pigmentary matter of the body. A simple division would be into — i, color STUDY OF DIAGNOSIS. 77 which has red for a basis ; 6, color which lacks red, is a shade of yellow, brown, black. In making examinations with reference to the blood, we select parts where the circulation is free and the epidermis or epithelium is thin — where the skin is thin, and the mucous membranes delicate. We examine the nails, the lips, the cheeks, the hands, sometimes the feet, the tongue, and mucous membranes of the mouth. What is the color of health as shown from the blood? It is rosy, a light shade of carmine and lake, and is clear, transparent, and offers no darkness, or admixture with blue, purple, or brown. As the finger is pressed upon the surface, or pressed over it, toward the heart, the rosy color is removed, leaving the structures clear and transparent, and the color comes back quickly when the pressure ceases. It is difficult to describe color in words, but if the reader will now make his examina- tions of health he may readily learn to distinguish the color of health. The shade of rose color in mucous membranes differs somewhat from the skin, because it is modified to some extent by the pigment in the rete-mucosum. It is well to get a clear idea of it by examinations of the lips, the tongue, the mucous membranes of the mouth, and fauces. The color of mucous membranes is quite changeable to a slight degree, even in health, having shades of blue, violet, white, probably from the secre- tions of the mouth, and the food and drink; and we never regard these slight variations as diagnostic. The pigment color of health varies in different races, and in different individuals. But if we say it is some- what transparent and clean, we may express its char- acter for all races. If we take a negro for example, we 78 STUDY OF DIAGNOSIS. will find the jetty black has a transparency and clean- ness — glossy and smooth, which will be readily recog- nized. Let this man become sick, and the color grows dingy and opaque. If we take the olive or brown skin, the same cleanness and clearness of color is marked, and it seems so transparent that you may almost look into the skin. If you take the Caucassian, the brunette will show the same clearness in the skin pigment, and in the healthy blonde it seems as if you cauld look quite through the skin, it is so transparent. We may even notice these peculiarities in the color of the hair, as it shows health and disease like other parts, but modified more by local conditions. In studying color, especially that given by the pres- ence of blood, it is well to note that it may be changed in quantity (so to speak), and in kind. Change in quantity has reference to an increased circulation, and an increased amount of blood in the capillaries; change in kind, to the condition of the blood. Simple excess may be noticed from any cause increas- ing the circulation to the surface, or to a part. We ob- serve this excess of color in slight acute diseases, where the activity of the heart is increased, and there is gen- eral vascular excitement. It is not an unpleasant symptom, and points clearly to the arterial sedatives, Aconite and Yeratrum, as the special remedies. If a part of the surface shows this excess, we at once think of its relation to internal organs and functions. If of the upper portion of the face and eyes, we refer the wrong to the brain. If of the cheeks, one or both, we refer it to the respiratory organs or apparatus of circulation. If of the mouth and lower part of the face, we refer it to the abdominal viscera. STUDY OF DIAGNOSIS. 79 As the excess refers to vascular excitement, and means general sedatives, so these local excesses mean local vascular excitement and local sedatives if we have them. Thus for the brain it would mean Gelseminum ; for the thoracic organs, Veratrum ; for the abdominal viscera, Aconite, Ipecac, etc. It is well to note the condition of the capillaries in this examination, and we may determine somewhat of their condition by the effects of pressure. If the capil- laries are in normal condition, pressure should efface the redness, but it is but momentary. If the finger is drawn across the reddened surface we notice the white line made by displacing the blood, but it rapidly passes away, and the blood flows quickly in and fills the ves- sels. If now we examine the redness in scarlet fever in the same way, we will find that the fingers carried over the part with pressure, effaces the redness, and leaves a distinct white line, more or less persistent, as the fever is severe. This shows enfeeblement of the capillary circulation, especially from the arterial side, and is an indication for Belladonna. In the larger number of cases, Aconite is the arterial sedative. The next best remedy to Bella- donna is the Carbonate or Hydrochlorate of Ammonia. If the capillary wrong is from venous obstruction, the color will be deeper, and the wrong will be asso- ciated with fullness of cellular tissue in many cases, and the white line made by pressure is not so clear. In this case, Podophyllin, Lobelia, Bryonia, are reme- dies. We not only find an excess, as above named, but in other cases a defect in color, showing poor blood, leuco- sythaemia, or an impaired circulation to the surface. The 80 STUDY OF DIAGNOSIS. pallor of anaemia is shown in all parts of the body, and is associated with evidence of impaired nutrition. In the rare pathological condition, leucocythsemia, there is sometimes marked pallor, but usually it is disguised by increase or change in the pigment of the skin. In de- ficient circulation to the surface, we have want of color, but no evidence of want of blood in totality, or impaired nutrition. Deepening of color — dark red — is usually associated with zymosis, and has reference to sepsis of the blood. It is associated with asthenia, and when observed it tells of impaired function. But it especially shows the need of acids, and in this respect refers to a direct remedy. It makes no difference where we find it most marked, its meaning is quite the same, of course modi- fied to some extent by local disease. If the reader Avill think for a moment of the cases he has seen presenting deep redness of the surface, he will recognize the truth of these statements. In typhus fever, the gravity of the disease is shown by the flushed skin — dark-red. If in smallpox, we find the skin assuming this dark-red color, we are confident the dis- ease will be severe, showing depravation of the blood, and marked asthenia. If we observe it in measles, we anticipate trouble from tardy appearance of the erup- tion, depravation of the blood, respiratory trouble, and impairment of function. If seen in pneumonia, it talks to us of approaching " typhoid symptoms," of a low grade of inflammation, and great prostration. So clear is the evidence, and so rare the exceptions, that it be- comes one of the most reliable evidences of disease we possess. The meaning is modified to a certain extent by the STUDY OF DIAGNOSIS. 81 results of pressure — whether the color is solid and un- yielding as the finger is pressed over the surface— or whether it is effaced by such pressure as heretofore named in simple excess. In the first case it has refer- ence wholly to the lesion of the blood, in the other in part to the lesion of circulation — at least the evidence is less grave. If the dark redness is an evidence of zymosis — sepsis — it speaks directly of antiseptics as a necessary part of the treatment. It says clearly — this patient must be kept clean, his clothing and the bed-clothing must be frequently changed, and kept clean and sweet, all the surroundings must be clean, he must have good air, fre- quently changed by good ventilation. It means further, that proper means shall be employed for disinfection when this becomes necessary. If the dark-redness is associated with asthenia and impairment of life, and gives us timely warning of such impairment, it will caution us against the use of all de- pressant remedies, or anything that will impair any of the important functions of the body. And it suggests the necessity of keeping the stomach in condition to receive food, and the proper selection and preparation of food during the progress of the disease. But it directly refers to acids as remedies, and this is of much importance. Acids here are the antiseptics and antizymotics. We give Muriatic Acid, Acetic Acid in the form of good cider, and Lactic Acid in the form of whey, and we find the condition of the patient markedly improved. Muriatic Acid is especially the antiseptic, though the others have an influence in this direction. The dull purple (bluish) of venous blood has reference 82 STUDY OF DIAGNOSIS. to imperfect venous circulation, and imperfect decarbon- ization of the blood. It may be caused by disease of heart or lungs; if not we recognize a lesion of sympa- thetic and associate spinal nervous systems. It evi- dences an unpleasant condition of life, and one that should be removed if possible. In some cases the dull- ness of color becomes so marked, that we designate it as leaden. If we find local structural disease to account for it, this will receive our attention. If it is sudden, and associated with precordial oppression and constriction of the chest, Lobelia is the remedy. If less marked and chronic, we will think of Cactus, Digitalis and Pulsa- tilla. In acute cases, Chloroform counter-irritation around the lower margin of the thorax, gives speedy and marked relief. In the lesion of cholera we will find the blueness of hands and feet dependent upon enfeebled capillary cir- culation, the blood being loaded with carbonic acid gas. If the condition of the blood can be so changed, as to enable it to circulate, this passes off. This blue- ness with pallor is one of the most marked indications for common salt as a medicine. Want of color, with a shade of solid blue where the blood shows freely as under the nails, the lips, tho cheeks, and thin skinned portions of the body, may be assumed to indicate the want of Iron. A violet tint with increase of redness uniformly, or only where the circulation is superficial, is a prominent indication for Nitric Acid. Deep color, with purplish, brown, or black tinge, is a prominent indication for Baptisia. Color not deep, but muddy or dirty, of parts freely 8 STUDY OF DIAGNOSIS. 83 supplied with blood, is an indication for Sulphurous Acid. If there is this dirty shade with pallor, we would use Sulphite of Soda. When we come to study the local changes of color referred to the blood, we divide them into two classes, the one in which the change is to be referred to a lesion of some other part — sympathetic ; the other in which it is dependent upon local disease. The reader will notice that the significance of color must depend very much upon this, for whilst the one may have no refer- ence to the condition of the blood at large, or to any structural lesion, the other is wholly referred to the lesion of the structures, and to changes in the blood. We always want familiar examples to show that a method of study is likely to prove advantageous — that is a basis of fact, and we will adduce the three familiar cases of — change in the color of areola of the nipple, the dark line under the eyes in certain conditions of women, and the white line around the mouth in some intestinal diseases of children. Every practitioner will have noticed the darkened areola of the nipple as an evidence of pregnancy, but may not have had his attention called to it as an evi- dence of disease of the reproductive function. In wrongs of this function simulating spermatorrhoea, we will find this change of color marked, as we will in scanty menstruation with congestion, and in hyper- trophy of the cervix uteri. Of course we do not look for this, except in the diagnosis of pregnancy, but in this case it is one of the most valuable symptoms. If you should notice the deep color under or around the eyes in women, you would say at once there was a wrong of the reproductive organs or function, and you 84 STUDY OF DIAGNOSIS. would rarely make a mistake. If the tissues seemed dry, the eyelids sunken and contracted, it would be safe to say that the disease was one of irritation, and would probably be relieved by Pulsatilla and Macrotys, (especially if functional.) And if the eyelids were full, swollen, relaxed, that the disease was of congestion or atony, and would be benefited by Hamamelis, Apo cynum, Staphysagria, Phosphorus, Iron, etc. Many cases present themselves where we do not wish to suggest an examination of the reproductive organs at first, or there may be some reason why it should not be made at present, hence the importance of other means of knowing the character of the wrong, and the class of remedies we may select from. If one should notice the white line around the mouth, with full pallid upper lip, full or contracted mouth, he would at once refer the symptom to a wrong of the gastro-intestinal apparatus. The reference is undoubt- edly right, if we except the rare case in which the symptom is dependent upon lesion of the brain. There is a wrong of the stomach and bowels. What is the character of that wrong ? If the structures are full, it is pretty surely one of atony — a want of innervation and a sluggish circulation. If the structures are con- stricted and pinched, the wrong is very certainly one of irritation, excited innervation and circulation. Is it worth our while to read the evidences of disease in the patient's face? I think it is, especially when the remedies are at once suggested. The white line around the mouth — gastro-intestinal disease. With fullness of tissue — Podophyllin, Hydrastia, Santonine. With con- striction and thinning of structures — Aconite, Ipecac. But suppose we notice a peculiar bluish or leaden STUDY OF DIAGNOSIS. 85 tint to this white line around the mouth, and see a slight dragging down of the corners, we would recog- nize the gastro-intestinal lesion— remedy. Bismuth, or sometimes minute doses of Arsenic. Increased color of cheeks has been noticed as a symp- tom of thoracic disease for thousands of years. What relation has this flushing of cheek to the condition of the lungs ? Can you explain the nervous and vascular connections ? Evidently we can not tell why, and I doubt if the evidence would be any more valuable if we could tell why. This is one of many examples that the interrogatory — why? is not always a profitable study in medicine. We know the fact, that a habitual recurring flush of one or both cheeks has reference to an irritable or diseased lung. The persistent high color, even thougb it be a distinctly circumscribed spot, has a different meaning. If we notice this circumscribed flushing of the cheeks, our attention is at once attracted to the re- spiratory apparatus. Associated with frequency of pulse and increased temperature, it telle us of com- mencing tubercular deposit. In this case the one cheek is usually flushed. It may be remarked further, that this symptom is always associated with a wrong of the sympathetic nervous system, especially in its relation to circulation and nutrition, and in phthisis we only find the bright, flushed cheek with irritation. Sometimes there is quite as marked pallor, and the evidence would be a want of innervation. The bright-red flush of left cheek in acute disease is usually referred to thoracic disease, but does not always indicate it. It evidences a lesion of sympathetic and 86 STUDY OF DIAGNOSIS. spinal innervation, but is especially valuable as calling our attention to .Rhus Toxicodendron as the probable remedy. The deeper flush of right cheek is more frequently seen in disease of serous membranes and fibrous tissues, but is especially valuable because it points out Bryonia as the probable specific remedy. Whilst the bright color of the cheeks, where it has reference to disease of the respiratory organs, tells us of irritation and activity of circulation, deep color in- dicates impairment of the circulation and of the life. The livid, purplish color in some cases of angina pec- toris, may be taken as the type. We have it in much less degree in thoracic aneurism, in apoplexy of lungs, and in some very severe cases of asthma with conges- tion. The dark redness is always evidence of a difficult and imperfect circulation. There is a, pinkish color of parts freely supplied with blood, that is regarded by some as an unpleasant symp- tom. As this color becomes more pronounced, we ob- serve it in the veins as well. In women we may usually refer it to a menstrual wrong, which will be corrected by the use of small doses of Pulsatilla. Actea Alba, Helonias. For the chronic lesion we think of Phos- phorus, the Hypophosphites, the bitter stomachics, and food. Among the things that old women know is — that prominent blue veins crossing the nose in children is a si^n of feeble vitality, and it is quite as true as if a phy- sician knew it. There is something wrong in the life when you observe these cutaneous veins showing the distinct and constant blue line, whether it is across the nose, at the wrists, upon the back of the hand, over the STUDY OF DIAGNOSIS. 87 breast or abdomen, or elsewhere. Whilst it may not point out any special medicine, it does prompt us to ad- vise that the child have abundant out-door exercise, good blood-making food, and that it shall not commence study early, or be much confined until there is a much stronger and robust life. Unusual blueness of veins is a very good indication for Iron. If associated with pallor of surface, we may s< loot Iron by Hydrogen, or Yalett's mass, but if there is deep color of tongue, Tincture of Muriate of Iron. The color of the conjunctiva and sclerotic will some times give us information in regard to the circulation of the brain. If we find an injected conjunctiva (not the result of local disease), we conclude that the cere- bral circulation is similarly affected. If the color is bright, and the surface looks smooth and moist, we have evidence of determination of blood. If the color is deep and the surface looks dull and dingy, or dry and pinched, it represents hyperemia, with obstruction to the return of blood — the apoplectic condition. The dull, colorless eye is the best indication for Belladonna, though we use it when the eye is injected, with tortuous vessels. In superficial disease, the color of the part is a means of determining its condition, If we take the ordinary symptoms of inflammation, increased color — redness — is one of the first named as constant. Given increased color, with heat, pain and swelling, and we say there is inflammation ; but which of these will best tell us the real condition of the part? I should answer, color. If the color is bright, healthy red, we know at once that the inflammation is simple, and is not very likely to work a very great wrong to the part, or to the body 88 STUDY OF DIAGNOSIS. at large. It tells us of irritation, determination of blood, and of activity of circulation ; the second part of the wrong of circulation — stasis — is in but small pro- portion. It says, give general arterial sedatives, use local sedatives, get rid of increased heat, and establish secretion. The evidence is quite the same, whether we are looking directly at the inflamed part, or at some distant surface, that is influenced by sympathy. If the color is deep-red and dull, we are confident there is marked impairment of life and arrest of circu- lation. The fact that there is too much blood in the part is evident, that the capillaries are enfeebled, and the circulation in them is sluggish or arrested, that change has commenced in the stagnant blood, and that the life of the part will be destroyed, unless these wrongs are corrected. It saj^s distinctly, strengthen the general circulation, whilst you lessen its frequency, and conserve and sustain the life of the blood by rest and food. If a local application is to be made, it is now stimulant — we want to strengthen the life of the part. If we select an internal remedy that is to influence the part from the blood, this remedy must be stimulant or tonic in its character. If the part assumes a blue or purplish color we recog- nize venous stasis, and an obstruction to the circulation from the part. With our attention called to the nature of the wrong, we will find its cause and remove it if possible. My attention was first called to this evidence of venous obstruction in a case of fracture of the fore- arm, with laceration of the hand, in which a roller was applied before the splints, yet not very tight. Inflam- mation sprang up in the hand, and the third day came this bluish discoloration, with a great deal of local STUDY OF DIAGNOSIS. 89 trouble. The roller was removed, and the difficulty slowly passed away. I have seen the same wrong arise from the position of an extremity being such as to im- pede the circulation of blood. In some cases the wrong being general, venous im- pairment is cardiac. We do not know why, bat we rarely find an impairment of the right heart, when the left is sufficient for the systemic circulation. Lobelia in stimulant doses exerts a very favorable influence in these cases. If there is fullness of cellular tissue, Apocynum may be associated with it, or given alone. If the wrong is from venous impairment, and is chronic, Hamamelis is probably the remedy. The erysipelatous redness is so distinctive, that being once seen it can hardly be forgotten. The vivid color- ation, evident dryness, shining appearance, give the be- holder a sense of burning. It makes no difference so far as the significance of this coloration is concerned, whether we have the local inflammation of the skin or not, it refers us to a lesion of the blood, zymotic in character. If the surgeon find this tint of vivid red- ness on the edges of a wound, or the flaps of an ampu- tation, he would be at once on the alert to get rid of the lesion of the blood. If the physician observed this erysipelatous flush on the cheek in inflammation of the lungs, or any where on the surface during the progress of an inflammation or fever, he might feel sure he would have a more than usually serious case to manage. We may distinguish four shades of this erysipelatous redness quite well marked in many cases, pointing out the remedies for the disease of the blood, and the local inflammation. In the first the redness is quite vivid, and the edges of the local disease show a simple erythe- 8 90 STUDY OF DIAGNOSIS. matous flush, and the part does not look dry and con- stricted. Sometimes there is arterial throbbing of the part, and the pulse is full. In this case Veratrum is the general and topical remedy. In the second case the redness is very vivid, and the parts dry and constricted, with sometimes the appearance of a slight pustular eruption. The pulse is small, sharp, vibratile ; the remedy is Eh us Toxicodendron. In the third case the redness has a deeper shade, sometimes vivid, sometimes dull. The remedy, both general and local, is Tincture of Muriate of Iron. The fourth case shows more or less of a blanched appearance, as the disease advances : sometimes in the centre, sometimes at the borders, sometimes of the deep structures — you seem to be look- ing through the superficial redness. In these cases the general remedy is Sulphite of Soda, the local remedy Sulphurous Acid, Permanganate of Potash, or Carbolic Acid. The variations of pigment color in different individ- uals is so great in health, that it might seem almost im- possible to get definite information from its variations in disease, yet I think we will find it quite as certain as other evidences of disease. Of course we must have a correct idea of normal pigment coloration, and some guide to the natural tint of the individual. Transpa- rency and cleanness are the characteristics of health, whatever may be the shade. The lesions might be divided into those of excess, defect and perversion, though the last is the most important. Excess of pigment, when it retains the clearness and transparency of health, is usually evidence of active life, and good nutrition and excretion. Of course out- door exposure is always taken into consideration, as STUDY OF DIAGNOSIS. 91 causing an increase of pigment. Local excesses of pigment have a variable meaning, though if still clear and transparent we think of functional activity. If we take the areola of the nipple, the clean, transparent, deep color evidences healthy gestation, as does the deepened color over the gland. The increase of abdom- inal pigment has the same meaning, as has the increased pigment color of the vulva. Even the increased pig- ment of face observed during gestation is an index of healthy function. Not so the unequal and unpleasant brownish coloration known as morph. The deep pigment coloration of the neck in brain workers is a sign of healthy nutrition of the nerve centres, whilst the want of pigment would indicate anaemia, and the dirty pigment would show a wrong of nutrition. The coloration of the skin and hair have the same associations. The clear, transparent color is the evi- dence of health, especially of the skin. The deepened color is evidence of an active life, especially of the vege- tative functions ; whilst a loss of color is at once re- ferred to impaired nutrition. Even the color of the hair is subject to slight changes, and one may learn to distinguish by this the condition of the nutritive func- tions. It is an unpleasant sign to find the hair becom- ing dull and sickly in color. There is an increase of pigment distinctly brown, and in patches on various parts of the body, which is known as " liver spots." They generally make their appearance on parts covered by the clothing, and may be quite large and extensive. We refer them to a wrong of the bile pigment, and frequently find it asso- ciated with a wrong of digestion, and impairment of 92 STUDY OP DIAGNOSIS. the function of the brain. The remedy is Podophyllin, associated with its natural bitter principle, Bebeerina, (Hydrastia). The brownish-yellow coloration is evidence of a wrong of the organs of digestion. We may find it only about the mouth or the face, or we may find it pretty general where the lesion is chronic. It refers us to Nux Vomica as the remedy. Give us the same color, but dull and opaque, or with a leaden tinge of adjacent skin, and we again refer it to a lesion of the organs of digestion. The remedy is Chelidonium ; Podophyllin, if the tissues show more than usual fullness. The bright yellow of jaundice is a symptom of wrong of the liver. What the condition of the liver may be other symptoms must decide. But in so far as the color is concerned, we expect to wash it out through the kidneys. There is a peculiar sallowness with a tinge of green that indicates great impairment of blood-making and nutrition. The remedy is Copper; we usually give Eademacher's Tincture. No one could mistake the opaque, tallow-like color of hypochondria, and associate states. It tells us of impairment of the digestive and blood-making organs, of nutrition, and of waste and excretion. There is a slow renewal of life, and the tissues are old and feeble. Very clearly in this case we want a more active " re- newal of life/' and we stimulate the processes of retro- grade metamorphosis and excretion on the one hand, to remove the old structures, and see that the function of digestion is well performed, that we may have in- creased nutrition. STUDY OF DIAGNOSIS. 93 One could hardly mistake the evidence of the dingy, dull, grimy, dirty color of skin. It refers us to a wrong of the blood — " bad blood," and we conclude that the blood is as dirty as the skin. Of course it would not do to mistake the dingy, dirty skin of the " great un- washed," but this is not very likely. Soap and water will show the difference. In this case remedies to in- crease secretion, and sometimes to promote retrograde metamorphosis, hold the first place, though we do not forget the importance of improved nutrition. There is a deepened tint of skin, dull and opaque, that is a very good indication for Arsenic or Phos- phorus. The tissue seems to have lost life, and is in- elastic. Dullness of color and opacity, may be regarded as the special features ; and opacity where the color is lighter than usual may indicate the remedy. If we have a distinct want of pigment, the want of color not dependent upon anaemia, or an enfeebled cir- culation of blood, we think of Sulphur as a possible re- storative. Given in small doses, we sometimes find it exerting a marked influence upon the nutritive pro- cesses. EXAMINATION OF THE TONGUE. " Let me see your tongue," says the doctor at every visit, though what he expects to learn from " seeing the tongue " he would be puzzled to tell you, unless it was that the patient was " bilious." Of course habitu- ally seeing the tongue in disease will, unconsciously, many times, grow some knowledge of its diagnostic value, and if the physician is a close observer, it will give him valuable aid in determining the character of 94 STUDY OF DIAGNOSIS. disease. But many men are so little in the habit of using their eyes, and thinking for themselves, that they learn but very little. If we think for a moment, we will see that the tongue may tell us of — a, the condition of the digestive appa- ratus ; b, the condition of the blood; c, the condition of the nervous system • ind d, of the functions of nutri- tion and excretion. As these are important inquiries, indeed just the things we want to know, we will make the tongue talk as plainly as possible* We find the expression of disease in — a, its form ; &, its condition of dryness or moisture ; c, its coatings ; d, its color; and e, its motion. It is well to think of the subject in this methodical way, even though we are not able to follow it wholly in this study. The common idea of physicians is, that the tongue expresses the condition of the stomach and intestinal tract, and it should be examined with reference to this ; few think that it may give further information. Being a part of the digestive tract, supplied by the same nerves, and invested by the same mucous membrane, we would naturally expect it to show something of the condition of parts below. If we say that its condition may be taken as the type of the condition of parts below, we will not be far out of the way. True, there are many exceptions, but the rule is a very good one, and will hardly lead to serious error. The mind at once recognizes the changes of form, movement, condition, color, and secretion, as ex- pressions of local disease. It will not be far wrong, if it recognizes them as expressions of disease of the entire digestive apparatus. Change of form is quite expressive, and rarely leads STUDY OF DIAGNOSIS. 95 us into error. The elongated and pointed tongue ex- presses the condition of irritation and determination of blood to stomach and intestinal canal very distinctly, and it is safe practice to give it full weight, and be very careful in the administration of remedies. As it is associated with excitation of the nerve centres, this is to be taken into consideration, when we value the evi- dence with reference to the stomach and bowels. If we observe this change of form early in the disease, we not only anticipate unpleasant gastric irritation through the sickness, and use care in avoiding irritants, but we employ means to remove it. Among these may be named minute doses of Aconite, Ipecac, Hydrocyanic Acid, Peach-bark infusion, small doses of Ehubarb, and Bismuth. The full tongue, broad and thick, is the evidence of atony of the digestive tract, especially of the mucous membranes. In this case the stomach and intestinal canal tolerates the common medicines given, and the use of cathartics is less harmful, and may be more bene- ficial than in others. The pinched, shrunken tongue expresses a want of functional activity in the digestive apparatus. It is the tongue of advanced acute disease, and is usually asso- ciated with dryness. " Want of functional activity " hardly expresses the condition, for the life of the diges- tive apparatus has suffered to such an extent, that there can be but little function. Whilst it is one of the indi- cations of want of food, it causes us to be very careful in its selection and administration, giving small quan- tities at a time, and at such periods as the unpleasant symptoms are least marked. The fissured tongue in chronic disease points us to 96 STUDY OF DIAGNOSIS. lesion of the kidneys inflammatory in character. In some cases the fissures are transverse only, but in severe cases they are somewhat irregular, and by pressing the tongue down it is seen to separate in irregular patches of prominent villi. The symptom is so definite, that one may be assured of inflammation when this tongue presents. The fissured tongue in the advanced stage of febrile diseases refers us to lesion of the kidneys, or irritation of the nerve centres. In many cases we find a wrong in the secretion of urine, and close examination shows a condition of kidneys bordering on inflammation. It deserves careful consideration, and especially means to place the skin in better condition, and to allay irrita- tion of the cerebro-spinal centres. The conditions of dryness and moisture are important evidences of the condition of the intestinal tract. If the tongue is dry, we are sure the stomach and intes- tinal canal can do but little digestive work, and we give it as much rest as possible. In such cases food is always given in fluid form, and usually above the temperature of 100°. It is also carefully selected and prepared, that the labor of digestion may be as small as possible. If the tongue is dry we are confident there is want of secretion from the intestinal canal and associate glands, and indeed that there is a condition present which will prevent the action of direct remedies to favor secretion. It is most absurd to employ cathartics in such cases, unless the object is simply to remove irritant accumula- tions. Moisture, on the contrary, expresses a condition favorable to functional activity. True, there may be impairment of function, as when the tongue is full, showing atony, or heavily coated, showing increased STUDY OF DIAGNOSIS. 97 mucous secretion, or dirty, showing depravation of the blood and secretions. If in acute disease with dryness of the tongue, we observe it becoming moist, we are confident of improve- ment, of the establishment of secretion, and indeed of all the vegetative processes. Having this meaning, it is nearly alwaj^s regarded as a favorable symptom. The coatings of the tongue are observed with care, as they are thought to be especially symptomatic of the condition of the digestive tract and the " liver."* * Appearance of the Tongue as a Symptom of Disorder of the Stomach — The aspect of the tongue was held by the older writers in medicine to be one of the most important criteria of the state of the digestive organs; and its morbid appearances were therefore carefully observed and minutely described by them as indications for both diagnosis and treatment In more recent periods, however, the value of the evidence furnished by this organ has been, if not entirely denied, at least so greatly depreciated, that it seems desirable to ascertain what are the limits of our knowledge with regard to the association of changes on its surface with those occurring in lower portions of the alimentary canal. The question appears to be capable of being resolved into three principal divisions : 1. What are the nature and causes of the alterations in the tongue which have been regarded as diagnostic of affections of the stomach ? 2. In what other diseases, occurring independently of stomach affections, are these changes observed ? 3. What is the nature of the alterations of the digestive organs with which these conditions of the tongue have been found to be associated ? The appearances of the tongue which have been most com- monly believed to be associated with the diseases of the rest of the intestinal canal, are (a) an increase of its epithelial covering 9 98 STUDY OF DIAGNOSIS. Whilst there is much of error in the common ideas of "furred tongue," something valuable maybe learned. The vivid whiteness of the tongue, evidently a change in the epithelium, evidences simple functional wrong, and is associated with the febrile state. If observed at other times, it may be taken as an indication that the stomach and digestive tube want rest. The thin, transparent mucoid coating of the tongue, evidently upon and from the secretions of the mouth, evidence enfeebled digestive function, frequently from intemperate eating or drinking. or "fur," which may present various degrees of thickness, and different shades of color; (b) enlargement of its papil; (clae ) various shades and degrees of redness of the mucous membrane ; and (d) certain alterations in its size and shape. (1) The fur or coating (saburra,) has been shown by micro- scopic examination to consist of epithelium scales, which are often fattily degenerated, and sometimes massed together, of free fat drops, and of confervoid growths ; of these the largest pro- portion is formed of the epithelial cells which are derived from the covering of the organ together with the saliva and buccal mucus, which in drying form a thick glutinous material, con- glomerating the other elements into a mass. The fur may be of greater or less thickness, dry or moist, uni- form, or accumulated more particularly at the posterior portions* it is sometimes deeply fissured by sulci, which may extend into the mucous membrane beneath. At other times it may separate in flakes from the surface, which then may look raw, and of a deeper red than natural, but which may, when the process of separation is gradual, present no deviation from the normal appearance. Mixed with the fur may be sometimes found pigment, blood corpuscles, mucous or pus corpuscles, or the remains of vegetable and animal portions of food. STUDY OF DIAGNOSIS. 99 The fur which has consistence is evidently upon the tongue, and can be scraped off — evidences impairment of function, and the wrong is generally in proportion to its thickness. If uniformly distributed it may be regarded as having reference to the entire intestinal tract ; if restricted principally to the base, we think of greater wrong of the stomach. The heavily loaded tongue would call our attention to accumulations in the bowels, and would prompt to means (mild) to secure their evacuation. The heavily loaded tongue at the base calls attention to accumulations in the stomach, and The color may be white or milky, or may present various shades of yellow or brown. The nature and cause of some of the changes in color are very imperfectly understood. Some of them arise from articles if food, medicinal substances, tobacco, etc.; a large proportion, how- ever, are caused by slight hemorrhages from the gums ; while some others, and especially those occurring in fevers, remain un- explained. Excepting, however, those cases where there is direct pigmentary discoloration from jaundice, when other tissues par- ticipate in the change, there is no foundation for the common belief that a yellow fur on the tongue has any necessary connec- tion with hepatic disorder. As regards the chief causes to which the production of this fur is attributable, may be mentioned: (a) Idiopathic conditions in which the tongue of some persons may, consistently with apparently perfect general health, form and throw off a much larger amount of epithelial covering than is ordinarily the case; inquiry should, therefore, be directed to this point before any general conclusions are formed respecting the indications to be drawn from its presence. Qb) States in which a coating is formed on the tongue by the Bimple drying of inspissated mucus and saliva, owing to the mouth being kept open, as is oft^n the case during sleep. (c) Conditions of irritation in the mouth itself, giving rise to 100 STUDY OF DIAGI^OSIS. suggests the use of an emetic to free this viscus, and stimulate normal innervation and circulation. Yellowness of coating is thought to arise from wrong in the hepatic function, and to point to the use of" liver remedies." Whilst it may have this reference in some cases, it is well to avoid the usual cholagogues. It may be said to call for Nux Vomica, small doses of Podo- phyllin and Hydrastine. A dull, leaden, yellow fur is an indication for Chelidonium. A dull, cheesy look- an .ncreased production of epithelium on the cheeks, gums and tongue, and which, from their similarity to the state of other mucous membranes, where increased secretion, attended with shedding of the epithe.ial covering, is the result of irritation or subacute inflammatory action, are usually termed catarrhal. The belief that this is the true pathology of this state,, is also favored by the coincidence, in many such cases, either of a gen- eral redness of the surface, beneath the thickened epithelium, or of hyperemia and enlargement of the papillae, especially of the papillae fungiformes of the lateral and anterior portions. In some instances, also, the inflammatory state is further evidenced by the production of aphthae, giving rise to slight and superficial ulcerations, with a reddened base, and often surrounded by a reddened margin. Many of these conditions of the tongue may, however, be due to local causes, such as carious teeth, or other sources of irritation to the fifth nerve, or to accumulation of food around the bases of the teeth, or to medicinal agents affecting the salivary glands and mouth, as Iodide of Potassium and Mercury, or to the habit of smoking (though this does not ordinarily produce a thickened epithelial fur, nor hyperemia of the papillae fungiformes, its effects being, generally limited to an enlargement of the papillae filiformes, which gives to the surface a finely roughened aspect). As smoking, however, is not an unfrequent cause of stomach affections, our observations on this head are always attended with certain grounds of fallacy. — Fox on Diseases of Stomach. STUDY OF DIAGNOSIS. 101 ing fur, with slight green tinge, is an indication for Copper. The bright redness of tip and edges, especially of papillae is an evidence of irritation with determination of blood. It always suggests care in the use of reme- dies, rest to the stomach, and the special agents named to remove irritation. A good condition of stomach is of first importance in the treatment of disease, and when these symptoms present, these means will hold a prominent place. The tongue gives us the best evidence of the condi- tion of the blood, and of the remedies which rectify its wrongs. All exudations or secretions from the blood must give information of the character of this fluid, and there is no better place to observe them than in the mouth. The circulation of blood is also very free and superficial in the tongue, and we are thus enabled to observe its changes of color better than in other situa- tions. The reader will recollect the distinction between the tongue itself and the fur or coating, when color is spoken of, as the one is from the circulating blood, and the other from the exudation. The broad, pallid tongue — marked want of color in the tongue itself — evidences the want of the alkaline elements of the body. The evidence is clear and dis- tinct, and the want one of much importance. It may be the basis of the entirety of the disease, which will fade away as soon as the proper alkali is given, or it may be but a portion of the wrong, and the alkaline salt prepares the way and facilitates the action of other remedies. If there is no special indication for some other, we prescribe Soda because it? is the salt of the blood. 102 STUDY OF DIAGNOSIS. Usually we direct the bicarbonate added to water to make a pleasant drink, and given freely as the patient wishes it. If there is predominant wrong of the mus- cular system, we may select a salt of Potash. If of tho cellular tissue, a salt of Lime. The deep red tongue, (usually contracted and dry), evidences the want of an acid, as well as that condition of the blood known as " typhoid." Here, as in the preceding case, the want of an acid (undue alkalinity of blood), may be the principal element of disease, and all the symptoms are ameliorated, and the patient con- valesces when it is given. In other cases it is but a por- tion of the disease, and the acid facilitates the action of other remedies. It is a very common symptom in typhoid and typhus fevers, and the use of an acid in these cases has been found a very successful treatment by Chambers, Anstie and others in the London Hospi- tals. Our Prof. King, some twenty-five years since, suggested the use of good sharp cider in these cases, and it has been employed with much success. He did not say there was deep redness of mucous membranes, but he might have said so, for he did name the dry and contracted tongue with dark sordes, and they are asso- ciated together. In this case we select with reference to the condition of the stomach, and the blood poisoning, and some- times we may defer to the taste of the patient. Muri- atic Acid usually receives the preference, as it is well borne by the stomach, is a natural acid, and is a power- ful antiseptic. It is added to water to make a pleasant acid drink, and given ad libitum. In some cases sharp cider is better borne by the stomach, is grateful to tho taste, and the small amount of alcohol in it is beneficial. STUDY OF DIAGNOSIS. 103 In others lactic acid, in the form of whey, answers an excellent purpose, as it furnishes a calorifacient food as well. The deep red, or deep violet colored mucous mem- branes, with fullness, evidences sepsis, and is an indica- tion for the special remedy, Baptisia. The acid should also be given in some cases. The full color, with violet shade, superficial and trans- parent, is the indication for Nitric Acid, and it will be found one of the most valuable remedies of the Materia Medica. The tongue large, thick in centre, with incurved edges, and of a dull blue, or leaden color, is one of the strongest indications for Arsenic, and it will rarely fail to arrest the progress of disease in such cases. The same dull, leaden color, with no change in size or shape of the tongue, is one of the best indications for the use of Phosphorus, or the Hypophosphites. The slick, raw-beef tongue, the papillae wholly effaced, evidences sepsis of the blood, and is one of the most marked of the " typhoid " symptoms. The color of the tongue is usually deep, and we will emploj r an Acid or Baptisia. The exudation or fur upon the tongue is a pretty good index of the condition of the blood. Of course we must weigh the influence of local disease of the mouth and teeth, and the sympathetic relations with the stomach and bowels, as heretofore named. (See note.) The dirty fur is an indication of sepsis of the blood, as well as of depravation of the secretions. It is fre- quently associated with moisture, and the redness is rarely increased. We use the common word " dirty/' 104 STUDY OF DIAGNOSIS. because it expresses our meaning clearly — the impres- sion upon the senses is that of dirt, and its meaning is dirt. It may be a dirty- white, a dirty -gray, a dirty- yellow, or a dirty -brown, but the dirty, grimy appear- ance always assumes prominence in the mind. If we have a dirty tongue, pallid, we usually think of Sulphite of Soda. If the redness is natural, we may use Sulphurous Acid or Sulphite of Magnesia. If dirty, with increased redness, Muriatic Acid. All shades of brown and black have reference to the condition known as typhoid. We have every shade of color from the slight tinge of brown to the deep brown or almost black. It is not only the coating of the tongue that shows this color, but accumulations of sordes about the teeth, and sometimes crusts upon the lips. As is the deepness of color, so is the wrong known as " sepsis," and so is the need of the class of reme- dies known as " antiseptic." As is the deepness of color, so is the impairment of life, and the need of care and rest to conserve it, and of food and restoratives to support it. These dark coatings are so usually associated with deep redness, that we usually think of acid remedies, first of which is Muriatic Acid. But some of the cases will need Baptisia, others Chlorate of Potash, and some will be benefited by Carbolic Acid. Cleanliness is of especial importance in these cases, as all decomposing animal matter in the air or surroundings, increases the wrong of the blood. The reader may not have thought that the tongue could tell him much with regard to the condition of the nervous system, and yet a little study will show that it does give very important evidence. It has STUDY OF DIAGNOSIS. 105 special reference to the condition of the sympathetic nervous system, and this may be regarded as the most important, but we also learn much of cerebro-spinal in- nervation. We associate dryness of tongue with excitation of the nerve centres, especially the ganglionic. So positive is the evidence that it is not possible to mistake it. Dry- ness of tongue is associated with vascular excitement, and with arrest of secretion from this cause. If in acute disease with dryness of tongue, we find it becom- ing moist, we know that the nerve centres are being re- lieved, and that the circulation is improved, and secre- tion is commencing. If in a case of disease marked by enfeebled innervation from the sympathetic, and moist, relaxed tongue, the tongue commences to dry and be- comes firmer, we know that this nervous system has been stimulated, and many times it is a first evidence of amendment. Whilst dryness always evidences undue excitement of the nerve centres, and calls for sedatives, or that class of agents which remove this, too much moisture and relaxation is evidence of the opposite condition. The reader will recollect the typical salivation from Mercury, and its influence in this regard, and will weigh the de- pressant influence of the mineral upon the sympathetic nervous system, by these conditions. If after mercu- rial salivation, the nerve centres are stimulated by Quinine, or Quinine and Opium with Ipecac, the tongue will become firmer and may become dry, and if not too great, this has been regarded as a good symptom. Moisture of tongue is one of the prominent conditions assuring us of the kindly action of Quinine, and even of Opium when indicated. If marked, and accompanied 106 STUDY OF DIAGNOSIS. by full, relaxed tissues, the patient always requires nerve stimulants. Contraction is always an evidence of an excited nervous system. Sometimes, indeed, we may measure the wrong of innervation by this symptom, as in typhoid and typhus fevers, and in the later stages of acute dis- ease. The reader who has seen the great nervous wrongs of these affections, will recollect the pinched, contracted tongue as one of the prominent symptoms. Fullness of tongue has the opposite meaning. If marked, we are quite sure that innervation is impaired from atony, or want of normal stimulus of the nerve centres, especially of the sympathetic. It suggests nerve stimulants as a part of the treatment, Podophyl- lin and Lobelia for the solar and cardiac plexus, Nux Vomica, Strychnia, Belladonna, Ergot, for the associate sympathetic and spinal nervous systems, and Quinine for the associate wrong of the three, or simply for the brain alone. Whilst the elongated and pointed tongue has especial reference to the stomach and intestinal canal, it is one of the expressions of disease of the base of the brain. It is well to note this fact, for we may have the wrong of the brain as the primary lesion, the nausea and vom- iting being but the result, and if treatment was wholly directed to the stomach, we would make a great mis- take. Gelseminum assumes a prominent place here, associated either with Veratrum or Aconite. Rest is obtained by the topical action of Chloroform about the ear. The small tongue, full in the centre, which is covered with a thick, tenacious mucoid coat, is an indication of marked disturbance of the brain, unless we have evi STUDY OF DIAGNOSIS. 107 dence of acute disease of ears, the globes of the eyes, or the sphenoidal or ethmoidal cells. It may indicate a very grave lesion, or in the latter case will pass away with the local disease. In those cases where the coat- ing is removed, the surface is left slick, and very dark colored. The tongue covered with a grayish or yellowish fur, showing small patches of red distributed uniformly over the surface, is the tongue of scarlet fever. The same appearance will be seen in other cases, where the capillary circulation of the skin is enfeebled. The eroded appearance of the papillae at the tip of the tongue, looking like small, rose-colored bubbles, evidences a peculiar wrong of the nerve centres and of the blood, for which Ehus Toxicodendron is the remedy. The movements of the tongue are sometimes of im- portance in determining the condition of the brain. If the patient has complete command over it, we conclude that the functions of the brain are still well performed. But if it is protruded with difficulty, is tremulous, or is inclined constantly to one side, we are confident we have a proportionate cerebral lesion. Whilst we might get the evidence elsewhere, it is quite as well to give weight to these symptoms, and when observed, to adopt means early for the relief of the brain. From what has been said, the reader will draw the conclusion that impairment of nutrition and secretion will be indicated by marked dryness and contraction on the one hand; or increased moisture and relaxation on the other. In the first case there is undue excita- tion, and if we select remedies to increase secretion or excretion, they will be of a sedative character. In the 108 STUDY OF DIAGNOSIS. other case there is a want of innervation, and the reme- dies will be those which will give stimulus and tone. There is a sodden, unpleasant looking tongue, which is quite as good evidence of cacoplastic material in the blood as any we can find. We recognize at once the evidence of enfeeblement of the digestive functions, and if there is local irritation we expect that the exu- date will be of this character, readily breaking down and destroying the tissues. EXAMINATION OF THE DISCHARGES. The examination of the discharges in common dis- eases is usually quite superficial, and whilst it has some diagnostic value is usually of little importance. The physician from force of habit asks after the discharge of urine and feces. Has the patient passed urine? freely? was it high colored, or what was its color? Has the patient's bowels been moved? how often? These are the common questions, and the answers are very uncertain and indefinite. Possibly the physician wishes to examine " the vessel," but in these days he is usually satisfied with these casual inquiries, and pre- fers to get his information from pleasanter sources. In the olden time examination of " the vessel " was of greater importance, for the principal part of the phy- sician's business was to fill it — medicine meant dis- charges. It may be well to give this subject a brief study, though we do not attach such great importance to it. We may divide the study into five parts — a, with refer- ence to the discharge from nose and mouth; 6, with STUDY OF DIAGNOSIS. 109 reference to the discharges from the skin ; c, with refer- ence to the discharges from the urinary apparatus ; d y with reference to the discharges from the bowels ; and e, with reference to the discharges from the reproduc- tive organs. From the Nose. — The discharges from the nose are of local significance, and indicate changes of function and structure in these cavities. In measles and typhus, catarrhal symptoms are among the most prominent, and in the first are almost pathognomonic ; but these and epidemic influenza are the only instances where the disease is referred to the blood. The thin, glairy secretion is evidence of irritation and determination of blood. The white of egg looking mucus of active inflammation. The yellowish, glairy discharge of commencing suppuration — muco-pus, and the opaque, yellowish, non-tenacious secretion, of the subsidence of inflammatory action. Dryness of the anterior nares is usually referred to scanty or arrested lachrymal secretion ; too much mois- ture of the anterior nares, thin, watery, to increased lachrymal secretion. In chronic disease of the nasal cavities, the condition of the parts is pretty clearly shown by the character of the discharges which have the entire range of mucus, muco-pus and pus. In determining the diagnostic value of these discharges, we will be guided by the same rules as in other situations. We wish to know the phy- sical properties of normal mucus, and of normal pus, and we will then have a standard of comparison ; this we will study in discharges from the respiratory tract below. 110 STUDY OF DIAGNOSIS. From the Mouth. — The discbarges from the mouth proper are of saliva with some mucus secretion. But through the mouth we have all the discharges from the respiratory tract below, of mucus, pus, blood, exudative material, etc. We also have occasionally discharges from the digestive tract, the stomach, upper small intes- tine, and secretion from the liver. The saliva normally is a thin, transparent, slightly viscid fluid, with a marked alkaline reaction to litmus paper. If it loses these properties in degree, or is iL- creased, we will conclude that the first act of digestion is improperly performed. Physicians have not been properly impressed with the importance of buccal diges- tion, and frequently direct their remedies to the stomach when it is not at fault. We have already seen that dryness of the mouth evi- denced arrest of secretion, and necessarily impairment of the digestive process. If the salivary secretion is found to be scanty, we anticipate a wrong of digestion, especially of starchy foods, and a wrong of nutrition. It is usually associated with excitation of the nerve centres, and local disease presents unusual irritation. We have the same results where the saliva is constantly thrown off in chewing and smoking. The remedies suggested in chronic disease by scanty secretion of saliva are, Iris Versicolor, Phytolacca, Panax, and some others of this class, with the Iodides and Bromides, especially of Ammonium. Increased secretion of saliva is found as a symptom in some forms of chronic disease, and occasionally in acute disease. If marked, it interferes with digestion, and is a cause of depravation of the blood. This may seem singular to the reader, and yet I think any one STUDY OF DIAGNOSIS. Ill who has closely observed cases presenting this symptom will bear me out. The tendency is always to low grades of albuminoid deposits — eacoplastic, or aplastic. In acute disease the remedies will be the Alkaline Sulphites or Sulphurous Acid, or sometimes Chlorate of Potash, or Chloride of Sodium. Quinine and Nux Vomica are thought of for the wrong of innervation, and Hydrastis and Podophyllin for the wrongs of the intestinal canal. The same remedies will be applicable in chronic disease, and in addition we may think of Phosphorus, Sulphur, and sometimes Arsenic. It is hardly worth w^hile to speak of changes in the character of saliva as regards its viscosity, as it is always associated with excess in quantity, and the indications for remedies will be as above. I would call attention, however, to the need of antiseptics in these cases, for very surely we will have sepsis as a prominent feature in the progress of acute disease. If the proper antiseptic is selected, as elsewhere described, whether Sulphite of Soda, Sulphurous Acid, Chlorate of Potash, Baptisia, or Muriatic Acid, this symptom will pass away. The reaction of the secretions of the mouth to test paper will be found to vary, and this will sometimes in- dicate the class of remedies to be selected. The alka- linity may be markedly increased, and acids will be as- sociated with remedies to influence the digestive pro- cess. In such a case, with dyspepsia, Muriatic or Lactic Acid, largely diluted, with the addition of a small por- tion of Nux, will cure when the ordinary means have failed. In infantile dyspepsia, w^e sometimes find the saliva neutral, or in rare cases the entire secretions of the mouth are slightly acid. We find the same condi- tions in the adult, though not so often nor so marked. 112 STUDY OF DIAGNOSIS. In such cases we would give Phosphate of Soda, and surely expect the patient to amend rapidly. From the Stomach. — Ejections from the stomach as the result of disease may sometimes give valuable in- formation, though usually we depend more upon what the patient tells us than upon what we see. But as a matter of interest we may examine the discharges. Eructations in dyspepsia are very acid or feebly acid. The first is very common and is usually met by an alkali or Bismuth, though experience shows that this is not good treatment, or at least but a part of good treat- ment. It is associated with hyperesthesia, demanding Aconite, Hydrocyanic Acid, Ehubarb, Ipecac, and like remedies ; with externally the wet pack, either of water or water with an acid. The second evidences a condi- tion of atony, and suggests Muriatic and Lactic Acids, with Hydrastis and similar bitters, Podophyllin, etc. Eructations containing a yellowish, or yellowish- brown coloring material, and of a bitter taste, shows irritation of the upper small intestine, and sometimes an irritation of the entire chylof>oietic apparatus. The remedies will be such as prove sedative to these parts. Blood in the discharges has a variable significance. If in small quantities, during violent vomiting, we may conclude that some mmr.te vessels have given away; if dark colored and clotted, we conclude there is passive hemorrhage — usually from congestion, except in the rare case of ulceration, with erosion of some of the vessels, when the discharge may either be of bright or clotted blood. Vomiting of considerable quantities of mucus is occa- sionally noticed in persistent atonic dyspepsia, and its STUDY OF DIAGNOSIS. 113 therapeutic value will be obvious. Vomiting of pus is at once referred to ulceration, the result of chronic in- flammation. The " black vomit " of yellow fever, and some rare cases of congestive, intermittent and remittent fevers, shows the breaking down of the blood, as well as the congestion of the digestive mucous surfaces. From the Eespiratory Tract. — The discharges from the respiratory tract are of mucus, pus, blood, and the material of exudation. As heretofore remarked, we wish to have a clear idea of the origin and value of these discharges, and senses trained to recognize them when seen. In health the respiratory mucous mem- brane is continuously lubricated with mucus, but it is not in quantity to be discharged by mouth ; even the increase of quantity is evidence of disease. If mucus is thin, glairy, and very tenacious, we know that it comes from a mucous membrane in a condition of great vascular excitement — inflammation. The more marked these proporties, the more active the excite- ment. We see it in minor degree in catarrhal bron- chitis, but most marked in sthenic bronchitis when secretion is first established. The typical remedy is Yeratrum. The opaque mucus, not so tenacious, is associated with a subsidence of the inflammation and resolution. The quantity may be such as to enfeeble the part or the patient, but other than this it is regarded as a favor- able symptom. The reader must not suppose from this that abundant opaque mucous discharges are essential to recovery, for they are not, and the patient convalesces better if the discharge is never in excess, and but little 10 114 STUDY OF DIAGNOSIS. changed in character. The typical remedy is Ipecac. Change of color evidences local structural disease, and disease of the blood, whatever the color may be. Shades of yellow and green show suppuration — the dis- charge is more or less purulent. Shades of brown, if not from blood in this discharge, show a low grade of inflammation and impairment of the blood. In some of these cases the discharges look like "prune juice/' or still worse, like the washings of spoiled beef. Globular sputa is characteristic of pneumonia, as the glairy, tenacious mucus is of bronchitis. So marked is this character of the expectoration in inflammation of the parenchyma of the lungs, that it is evidenced, not only in the single portions of mucus expectorated, but when the patient spits in a vessel, they all run together to form a globular mass. The cheesy expectoration, lacking consistence, seem- ing to be somewhat granular, is usually regarded as tuberculous. Whilst there are exceptions, it is prob- able that it may usually be regarded as evidencing aplastic or cacoplastic deposits, and a condition favoring tuberculosis, if it is not broken down tubercle. Masses of dessicated mucus are sometimes expec- torated, that are well calculated to deceive. They are in larger and smaller granules, and fully meet the popular idea of tubercular deposit. Yet when we take a portion and soften it with water on a glass, it gives the glairy, tenacious mucus, and not the friable, tuber- cular matter. These little bodies are evidently from accumulations in mucous follicles, principally in the larynx, which are forced out in the act of coughing. Pus from mucous membranes, will in appearance take the entire range of this product. It is usually admixed STUDY OF DIAGNOSIS, 115 with mucus, and thus has greater consistence. It is laudable, or bad, thin, thick, bland, ichorous, yellow, green, brown, etc. It evidences local destruction, though it may be but superficial, the relationship be- tween mucus and pus being very intimate. The grada- tions of pus have the same significance here as elsewhere. Blood may be discharged from the throat and pha- rynx, from the stomach, from the larynx, and from the lungs. From the throat and pharynx it is of usual color, is not frothy, and is ejected by an act of the will. Blood from the stomach is of darker color, is sometimes admixed with food and the secretions of the stomach, or is in part clotted. Blood from the larynx is but little frothy, is of usual color, and is in part discharged by an act of will. Blood from the lungs is usually bright, frothy, and wells up into the mouth without the con- sciousness of the patient. We always want to know whether hemorrhage is active or passive, as the treatment will depend upon this. Very fresh and bright blood would evidence active hemorrhage, whilst deeper colored blood would evidence passive hemorrhage. Yet we will find better evidence in the color and expression of the face and in the pulse. Active hemorrhage calls for Veratrum and Ipecac, whilst passive hemorrhage refers us to Erigeron, Gallic Acid and Ergot. Mucus streaked with bright blood evidences inflam- mation, and is seen in sthenic bronchitis. If the blood is less bright it evidences a lower degree of inflamma- tion, or rather impairment of the life of the part, and if it assumes the " prune juice " character, it evidences an unpleasant condition. The blood in the sputa of pneumonia is rusty, and maybe found perfectly admixed 116 STUDY OF DIAGNOSIS. with the mass of mucus, or forming a central nucleus. If here it becomes brown, or has the "prune juice" character, it evidences a low grade of inflammatory action and impairment of the life. We occasionally see exudative material. First, as fibrinous exudations from the mucous surfaces, in croup and in croupous bronchitis; second, as broken down tubercular material from the parenchyma of the lungs. The last is sometimes very characteristic, but at others it is so masked by the bronchial secretions and by the breaking down of the structures, that we can hardly recognize it. Gall it cheesy, friable, and the fluid dif- fering in character from laudable pus in consistence, color, etc., and the reader will get a fair idea of it. EXAMINATION OP THE TJKIJSTE. The physician in common practice has but little knowledge of the urine — possibly he maj^ not know the physical properties of normal urine. As we have stated so often, this is the first thing that needs be learned. If we can recognize normal urine when we see it, it will be possible to tell its common variations by sight. Yet here we find a serious obstacle in the way — the very great variations of normal urine both in color and in quantity. Yet there is a normal color, and these differences are more in its concentration than in any real change. The quantity may vary very greatly without any marked change in the excretion — water forming its bulk.* ^Composition of Kenal Excretion. — The renal excretion has naturally an acid reaction, and consists chiefly of urea, with some uric acid, sundry other animal products of less importance, in- STUDY OF DIAGNOSIS. 117 The majority of physicians attach but little value to the ordinary examination of urine by the sight, which is popularly known as " Uroscopy." Yet whilst we are convinced that there is a broad basis of charlatanry, there is evidently something real that serves as a basis for selecting remedies. Evidently it is worth study, and I think I can point out a method by which the reader can learn all there is to be known. It is claimed that all disease is represented in change of the urinary secretions, and that these changes can be recognized. Let us admit it, and then to study diagnosis by the urine we will take cases of disease eluding certain coloring-matters, and saline and gaseous sub- stances, all held in solution by a large quantity of water. The quantity and composition of the urine vary greatly ac- cording to the time of day ; the temperature and moisture of the air; the fasting or replete condition of the alimentary canal; and the nature of the food. Urea and uric acid are both composed of the elements carbon, hydrogen, oxygen, and nitrogen ; but the urea is by far the more soluble in water, and greatly exceeds the uric acid in quantity. An average healthy man excretes by the kidneys about fifty ounces, or twenty-four thousand grains of water a day. In this are dissolved five hundred grains of urea, but not more than ten to twelve grains of uric acid. The amount of other animal matters, and of saline substances^ varies from one-third as much to nearly the same amount as the urea. The saline matters consist chiefly of common salt, phos- phates and sulphates of potash, soda, lime and magnesia. The gases are the same as those in the blood — namely, carbonic acid, oxygen, and nitrogen. But the quantity is, proportionally, less than one-third as great; and the carbonic acid is in very large, while the oxygen is in very small, amount. The average specific gravity does not differ very widely from that of blood-serum, being 1.020. — Huxley. 118 STUDY OF DIAGNOSIS. where tbe diagnosis is well made, and compare the urine with the normal standard of health. Certainly we will now be able to see these differences if they exist. Here is the patient suffering with pneumonia, bronchitis, or tuberculosis. Is there a urine that represents pneu- monia^ bronchitis, or tuberculosis? Here are patients suffering from well recognized nervous lesions, neural- gia, paralysis, epilepsy, etc. Is there a urine that rep- resents neuralgia, paralysis, epilepsj', etc. ? Here are certain well defined lesions of digestion, blood-making, nutrition, and retrograde metamorphosis. Are there urines that represent these lesions of digestion, blood- making, nutrition, and retrograde metamorphosis? But supposing we do not find that these diseases are represented in the urines, and we can not diagnose the situation of local disease from it, possibly we can diag- nose a general condition of disease. At least we will very certainly learn what is to be learned, and we will learn something that is valuable. The ordinary examination is conducted with refer- ence to — a, quantity; b, specific gravity; c, color; and the person is not plethoric, we ask the question — is it dependent upon a more rapid movement of the mass of the blood, especially to the surface, or is it dependent upon an obstruction to its movement through the capillaries ? Freedom in the pulse-wave in- dicates the one, and a want of freedom — oppression — indicates the other condition. 150 STUDY OF DIAGNOSIS. The sharp impulse of the wave of blood, as it strikes the finger, may be referred to lesions of the nerve cen- tres, especially of the sympathetic. The wrong is of irritation, and calls for remedies that relieve it. If the impulse is sharp, the wave short, and the inter-cur- rent vibratile, the irritation is extreme. The dull, elastic stroke of the wave refers us to an impairment of innervation from the sympathetic and spinal cord. The more marked this is, the greater the necessity for those remedies which stimulate and give strength to these nerve centres. The length of blood-wave has reference to that con- dition known as " sthenia," an excitation founded on strong life. This is especially the case where the wave is large in volume, and well supported by the column of blood behind. The oppressed pulse is marked by a want of power in the stroke, and more especially by a feeling as if the current in advance of the wave broke its force. Evi- dently the blood-wave does not measure the amount of blood passing through the artery. It refers us to ob- struction in the capillary vessels, or possibly an impair- ment of the large vessels as well, or a wrong in the blood unfitting it for circulation. If the finger is carefully trained it will notice a vari- ation in the surface of the wave, as well as in its length. Many times it is distinctly felt as two waves — a first sudden and short, and a second full, even and prolonged The first may be called the shock-wave, and the second the sj^stolic-wave which represents the movement ol blood from the heart. The shock-wave sharp and pronounced may always be referred to undue excitation of the nerves distributed STUDY OF DIAGNOSIS. 151 upon the vessels, and an undue contraction or tension of their walls. The full, strong, systolic-wave may be referred to ex- citation of the heart and strength in its movement. The short, systolic-wave evidences a want of cardiac power, and especially of impaired innervation from the spinal cord and sympathetic. The inter-wave current sometimes gives valuable in- formation, and it is well for the reader to observe it carefully in health and learn its normal condition. We find in disease that it has more or less volume, has more or less strength, and has more or less of the vibra- tile quality. When we speak of a full pulse 3 we have reference to the inter-wave current as well as to the wave, and the condition of sthenia will be determined by this. It is strong life in a state of excitation. If now we add hardness, we have added an especial lesion of innervation, of excitation steadily maintained. If we speak of a small pulse hard, we refer it to im- pairment of life from activity, still maintained. If we have a small pulse soft and easily compressed, we refer it to deficient innervation. If we have a small pulse vibratile, we say it is the ex- pression of impaired life, with great excitation of the nerve centres. If we have an empty pulse, the inter-wave current hardly perceptible, it is the evidence of impaired life, with enfeebled innervation from the sympathetic. There are other changes of the pulse which might be noticed, bat they are difficult to describe and learn. I do not think that we can tell every lesion by it, as Chinese doctors believe, but to the educated touch it 152 STUDY OF DIAGNOSIS. gives most valuable information with regard to the most important functions of life. I doubt not many physi- cians can locate lesions with very great certainty from it alone ; that they can distinguish lesions of the brain, lungs, digestive apparatus, urinary apparatus, etc., and determine, to some extent, their character. But in the practice of medicine, there is something of more importance than locating a disease, or even de- termining the character of the lesion. The important object is to associate the evidences of disease with reme- dies for their cure, and to make the expressions of dis- ease point to the medicine. Feeling the pulse gives us a knowledge of the lesions of the circulation — most important information in the majority of diseases. Every lesion of the circulation is distinctly announced to the cultivated touch, as is some lesions of the blood and of the nervous system. In so far as we study the pulse, I desire that it shall mean special remedies — not names of disease. Frequency calls attention to a wrong of the circulation and prompts the asking of ther question — why? It does not necessarily mean Veratrum, Aconite, Gelsemi- num, etc., though it is suggestive of them. Why ? Is the wrong in the vessels an obstruction to the free circula- tion of blood, requiring an increased movement of the heart to compensate it ? Is the wrong an enfeeblement of the heart, requiring increased frequency of impulse to compensate for want of power? Is the increased frequency dependent upon irritation of the cardiac plexus ? Is the frequency dependent upon a wrong of the blood? Upon a cerebro-spinal wrong? The full pulse with strength means medicine — Vera- trum. Whether full and hard, full and bounding, the STUDY OF DIAGNOSIS. 153 special sedative named is at once suggested. It may not be all that the patient wants, but it is one, and in many cases will stand first. The full pulse doughy (lacks the marked vibration) means Lobelia ; or if marked and associated with full- ness of mucous membranes and purplish discoloration, Baptisia; or if accompanied with muscular pain, Apo- cynum. The full pulse open, is kindly influenced by Podophyl- lin, and especially by Quinine in full doses. The large pulse empty calls for the alkaline sulphites, Sulphurous Acid, stimulant baths or fatty inunction, Quinine, and histogenetic food. The sensation we get in this case is of an artery of large calibre, but with too little volume of blood — the sensation after the impulse being of emptiness. The full pulse vibratile calls for Gelseminum, usually associated with Yeratrum. The full pulse oppressed, calls for Belladonna, alter- nated with Yeratrum ; if sepsis, Baptisia. * The small pulse usually means Aconite. The small pulse vlbratile Aconite and Gelseminum. The small pulse oppressed Belladonna and Aconite. The small, soft, easily compressed pulse, Aconite, stimulants. Small doses of Quinine with Opium and food. The small pulse, frequent, easity compressed, the wave of blood giving a sense of squareness as it passes under the finger, Opium. Want of power in the impulse suggests Digitalis, Capsicum. The sharp stroke of the pulse with tremulous wave be- tween strokes, means Rhus. 154 STUDY OF DIAGNOSIS The sharp stroke of pulse, with even, small, vibratilo current between strokes — Bryonia. The dull stroke with tremulous or vibralile wave — Phytolacca. The open, tremulous pulse — Arsenicum. The small or open pulse in which the wave of blood drops suddenly as it passes the finger — Pulsatilla or Cactus. Irregularity of pulse, soft or open, with a distinct wrong in the stroke — Cactus. The steady, vibratile pulse, without marked wave — Macrotys. We have often reason to believe that Quinine is indi- cated bj^ the periodicity of the disease, and yet our ex- perience with the remedy raises doubts of whether it will be well received and exert a kindly and curative action. If the pulse is hard and vibratile, wiry, we will not give it; if it is soft and open we may expect its kindly action. The physician who would administer Opium or its salts with a hard, wiry pulse, would be doing his patient a great wrong. Here, also, we want a soft, open pulse for the kindly action of the medicine. No one in his senses would give Podophyllin when there was a small, wiry pulse, or when it had a sharp stroke — the patient might get through safely, and it might kill him. This is only a partial consideration of the subject, and the results of my own experience. It should agree with what others know of the pulse as a means of diagnosis, and 1 hope will be thoroughly proven. Even if proven to be without foundation in fact, the investigation will give practical knowledge, and will increase our knowledge of the relationship between the evidences of disease and remedies. STUDY OF DIAGNOSIS. 155 If the reader will notice carefully, he will see a marked resemblance between the touch of the pulse, and the general sense of touch when the hand is applied to the skin. The sensation from the slight oedema of cellular tissue, that indicates Apocynum, and the pulse that says Apocynum is wonderfully similar. The sen- sation from the skin that says Lobelia and the pulse that says Lobelia is the same. The pulse of Veratrum is associated with the skin of Veratrum. And so we will find it all the way through, if we see the indica- tions for remedies rightly they never conflict. THE TEMPEBATUKE. Among the evidences of disease, none are more defi- nite and important than changes in the temperature. Heat is not only force in the animal bod}^, but it is also a condition of life ; a man has activity through it, and he has life by it. The theory of Samuel Thomson — " Heat is life, cold is death," was very simple, and had much of truth in it — it was just one-third of the truth. Cold is death, but so is too high a temperature, and an unequal distribution of heat. The human body maintains its healthy functions at a temperature varying from 98° to 98.5°. This is a con- dition absolute for health. If the temperature varies from this above or below, disease must result. We may state the proposition in a different form — no disease can exist without changing the temperature of the body, either raising it, depressing it, or rendering it unequal. Thus, change of temperature becomes an absolute evidence of disease, though it may not point out the character or the location of the lesion. 156 STUDY OF DIAGNOSIS. In the olden time changes in the temperature were determined by the hand applied to the surface of the body. With some physicians the touch would be so educated that it would recognize these changes with considerable accuracy. Whilst it would not note the changes within one or two degrees when the tempera- ture was above, it would recognize certain alterations of the skin, and modifications of heat or electricity, that the body thermometer does not take cognizance of. This information is of great importance, and whilst we highly value the body thermometer, we purpose to cultivate the touch as far as possible. The Body Thermometer. — The thermometer is pre- sented to us as a new means of diagnosis, but as far back as 1754, one hundred and twenty years ago, An- tonius De Haen, the first clinical teacher of medicine at Yienna, insisted upon its use to determine the tem- perature of the body, rather than to judge by the hand. But though De Haen showed that it was the only cor- rect index of heat, and seemingly indispensable in diagnosis, if it was desirable to determine the temper- ature, he was not able to convince the profession that this was desirable, and its use lapsed with his death. The use of the thermometer has been revived within the last fifteen years, and is now exciting much attention, and is employed by many as a most valued means of diagnosis and prognosis. It is valued now, because we appreciate the fact that the vital processes can only be performed in perfection at the normal temperature of 98°, and that just in proportion as it varies from this, either above or below, they are changed or arrested. Indeed, it would seem, that heat, at this degree, was thu STUDY OF DIAGNOSIS. - 157 most essential condition of life, and that if there is a variation from it, those means which will restore the thermal equilibrium are the most direct and important. The difficulty in the way of using the thermometer to determine the temperature of the body, seemed to be in a want of sensitiveness, and precision in marking fractions of a degree. This has been overcome by em- ploying a large quantity of mercury in the bulb, and a short stem graduated from 80° to 115°. By thus in- creasing the quantity of mercury, the degree, as marked upon the scale, was so lengthened that it could readily be divided into fourths, and even eighths or tenths. And the sensitiveness to heat was in direct proportion to the increased length of a degree as marked upon the scale. A registering thermometer is one in which a small por- tion of mercury is detached from the main column in the stem of the instrument. This detached portion is elevated by the expansion of the mercury below, which ascends in the stem below it, and thus marks the degree of heat. But it is not influenced by the descent of the main column, but remains in its place, thus acting as a register. In using this thermometer, the detached por- tion of mercury is lowered in the stem below the register by giving it three or four gentle taps with the hand from below. As the instruments require great accuracy in manu- facture, they exceed in price the ordinary thermometer. Tet very good instruments may be purchased for $2.50 to §5.00; the self-registering, in morocco cases, I would recommend as preferable. It may be remarked, that we employ thermometers graduated to Fahrenheit's scale, but some of the 158 STUDY OF DIAGNOSIS. cheaper German instruments have the scale of Reaumur or Centigrade. Applying the Thermometer. — The majority of writers direct that the thermometer be applied in the axillae, as it is there completely enclosed and sur rounded by the soft parts. When it is convenient, as in some acute diseases, the person being in bed, I think the axillae the best, yet there are many cases when we should like to test the temperature, that it would be very inconvenient for the person to unfasten the clothes to reach this part. Women, especially, will object to this method of examination. To suit these cases, I apply the bulb of the ther- mometer under the tongue, having the patient close the mouth. This is much more convenient, and so far as my experience extends, just as reliable. The thermometer should be retained in its place from three to five minutes, as it requires this length of time for the full influence of the body's heat. It is well also, in some cases, to watch the register to see how rapidly the mercury rises, as there is much difference in this in different cases, and it also becomes an element in diagnosis. Ranges of Temperature in Health. — The standard temperature of the healthy body is 98.5°, and is sub- ject to a slight variation during the day of about 0.820°. The maximum temperature is in the early morning; it fluctuates and gradually decreases during the day, and is lowest at midnight. " The observations of Drs. Edwards and Davy have shown that the amount of animal heat may be consid- erably altered by a number of collateral circumstances. STUDY OF DIAGNOSIS. 159 But the great distinction between these alterations of temperature in health, and those which are the result of disease is, that these variations are generally tempo- rary, and within narrow limits — amounting to mere fractions of a degree — rarely more than 1.8° Fahr. to 3.6° Fahr. whereas those which are due to disease are persistent so long as the disease exists. " The following are the collateral circumstances which mainly influence animal heat in our daily life, and which require to be remembered in order that erro- neous conclusions may not be drawn: 1. Active exercise [not carried to the extent of exhausting fatigue] raises the temperature proportionally to the degree of mus- cular exertion made. 2. Exposure to cold without exer- cise lowers the temperature. 3. Sustained mental ex- ertion reduces temperature about half a degree* 4. The amount of heat is also reduced by a full meal and the use of alcohol ; but it rises again as digestion advances. 5. There are diurnal fluctuations capable of being thus determined. 6. The temperature of the body rises with the temperature of the air ; and sudden transitions from a cold to a hot climate induce a feverish state marked by increase of temperature on bodily exertion. 7. The average temperature within the tropics is nearly 1° Fahr. higher than in temperate regions. 8. The temperature is more readily and rapidly affected — more sensitive, so to speak — than either the pulse or the res- piration ; and this is especially the case in disease." — Ait ken. Eanges of Temperature in Disease. — We have to study both an increase and a decrease in the temperature of the body, the first being of most common occurrence 160 STUDY OF DIAGNOSIS. and having the greatest range. Thus whilst a decrease of but one degree, if maintained for a considerable time, will result in death, an increase of two to four degrees may be maintained for a month with safety to life. The increase of temperature is usually proportionate- to the frequency of the pulse, one degree corresponding to an increase of ten beats per minute. Thus : With a temperature of 98° pulse of 60 99°. 100°. 101°. 102°., 103°., 104°. 105°. 106°. 70 80 90 100 110 120 130 140 This table is for adult males of good development, and will not apply to those of feeble constitution, of sedentary habits, or of a nervous temperament. In such, with a normal temperature of 98°, the pulse would be 70 or 80, and the increased frequency to each degree would be but six or eight, until the 103° was passed. In chronic disease we also find an increase of tem- perature, and the thermometer becomes almost as cer- tain a means of diagnosis and prognosis as in febrile and inflammatory affections. Thus, for instance, in phthisis pulmonalis, we find a permanent increase of temperature to 99° and 100°, in the 'first stages, in- creasing to 101° and 102°, as the disease progresses. This increase is so uniform that it will furnish the best evidence of the nature of the disease in its earliest stage. The frequency of the pulse corresponds to the increase STUDY OF DIAGNOSE. 161 of temperature. Breaking down of the tubercles is announced by a marked increase of temperature, cor- responding to the destruction of lung tissue, and the danger to life. In acute fevers and inflammations, we find the tem- perature increasing in the ratio of the severity of the disease. It does not, however, remain uniformly the same throughout the twenty-four hours, but presents a marked morning decline and evening elevation. This is very distinct, even in continued fevers, which we are accustomed to think of as being uniform in all their phenomena. This fluctuation is rarely less than one degree, and is frequently two degrees cr more. The value of the thermometer, as a means of diag- nosis, is thus estimated by Dr. Aitken : " In the course of many diseases, whose diagnosis has be^n accurately determined, if the temperature de- parts from its normal or typical range, the thermometer will furnish the best and the earliest indication of any untoward event, such as the additional development of disease, or other visceral complications, in its course. " When once the typical range of temperature (nor- mal, as it were, of the particular disease) is determined, a basis is laid for appreciating irregularities or compli- cations in its course in particular cases. For example, a patient exhibits symptoms of fever of the typhoid type, but during the progress of the first week his tem- perature becomes normal, for however short a space of time — the occurrence of this event proves that the fever is not what it was suj)posed to be. Again, a patient may suffer from all the general symptoms of incipient pneumonia ; but there still is a doubt as to whether in- farction of the lung has taken place. The sputa being 14 162 STUDY OF DIAGNOSIS. suppressed, or not procurable, does not assist the diag- nosis. If, however, the temperature is found to be normal, it is certain that no croupous exudation has taken place in the lung, and that there is no pneumonia. Again, if a tuberculous patient has a sudden attack of haemoptysis, and if the temperature of his body is normal during and subsequent to the. attack, no reactive pneumonia, nor any exacerbation of the tuberculous exudation need be expected. This is a new field open for investigation in cases of phthisis. " Again : In all cases of convalescence, so long as the defervescence proceeds regularly, as measured by the temperature, no relapses need be feared ; on the other hand, delayed defervescence in pneumonia, the persist- ence of a high evening temperature in typhus or typhoid fever, or the exanthemata, and the incomplete attainment of normal temperature in convalescence, are signs of great significance. They indicate incom- plete recovery, supervention of other diseases, unfavor- able changes in the products of disease, or the continu- ance of other sources of disturbance requiring to be carefully examined into. The onset of even a slight elevation of temperature during convalescence is a warning to exercise careful watching over the patient, and especially for the maintenance of a due control over his diet and actions." The Influence of Treatment on the Tempera- ture. — By reference to table on page 160, it will be noticed that there is a constant relation between the frequency of the pulse and the temperature : that with a range of temperature of 103° to 105°, we find a pulse ranging from 110-115 to 130-140. It is evident, there- STUDY OF DIAGNOSIS. 163 fore, that if we have any means that will control the circulation — lessening the frequency of the pulse — it will also lower the temperature. The question then arises, if a treatment will thus control the pulse and temperature, may it not change a severe and dangerous case into a mild one without danger? We answer this question in the affirmative, not as a theory, but from observations on many cases of disease. I think I am justified in stating, as an axiom, that just in the ratio that the circulation is thus controlled, and the temperature reduced, the fever is rendered mild. I wish it distinctly understood, however, that I refer only to those influences which can be continued for some days, and not to those which endure but a few hours. The use of large doses of Veratrum will bring down the pulse from 120 to 60 or 70 beats per minute, in six to ten hours, and with a corresponding reduction in temperature ; but it is not possible to continue this influence, as in a few hours the stomach becomes irri- table and rejects it, or the depression of the sympathetic nervous system is such as to peril life. But if the remedy is given in doses of half to one drop, sedation is slowly produced, the stomach receives it kindly, and instead of depression of the vegetative functions, the remedy acts as a stimulant to them. But is it possible to arrest a fever before it has run its course? I am satisfied that this question may also be answered in the affirmative. Not that every case can be shortened, for in some the local lesion of Peyer's glands proves an insurmountable obstacle ; but many can be arrested from the seventh to the ninth day, more 164 STUDY OF DIAGNOSIS. by the fourteenth, and in nearly all the disease can be restricted to twenty one days. A fever terminates naturally — by a decrease in the frequency of the pulse, a diminution of the tempera- ture, and the re-establishment of secretion, by which the cause of the disease is removed. If, then, by the use of sedatives, we lessen the frequency of the pulse, and obtain an equal and uniform circulation, with a corresponding decline in temperature, we find it easy to establish secretion from the skin, kidneys and bowels, by the usual means. And in a majority of cases these processes may be sustained by the use of nutritious food, and the use of small doses of the Bitter Tonics. But the question arises, does the temperature bear the same relation in chronic disease, and will treatment influencing the temperature have a like curative influ- ence? I answer the question in the affirmative, and adduce as an example phthisis pulmonalis, one of the most intractable diseases we have to contend with. In this, so long as the increased temperature is main- tained, the disease progresses ; and very frequently its rapidity is in exact ratio to this. Diminish the temper- ature, and the disease progresses more slowly. Reduce it to 98.5°, and maintain it at this, and the patient re- covers. The wrong of temperature is but the expression of disease. If the disease is favorably influenced by rem- edies the temperature falls or rises towards the normal standard. I'hus in a given case of disease we may see the pathological wrong, whether of the blood, the nervous system, or of waste and excretion, and at the same time the indications for the remedy which will STUDY OF DIAGNOSIS. 165 right the lesion, and we know that its use will reduce the temperature. Thus in a case of zymotic fever the evidences of sepsis are marked, and with sepsis there must be an exalted temperature. If now we select the right antiseptic, say Sulphite of Soda. Chlorate of Potash or Baptisia, the temperature will fall with its use. If in any given case we have a special indication for Nitric Acid, for Podophyllin, Quinine, etc., they will influence the temperature toward the normal standard. But in many cases the wrong of temperature may be regarded rather as a cause than as a result. If the temperature is above the normal standard the functions of life are impaired in the ratio of the excess. Thus as we have already seen — increase of temperature is asso- ciated with acceleration of the pulse — increase of tem- perature is associated with frequent respiration. With an increase of temperature there is an arrest of diges- tion, blood-making, nutrition, waste, retrograde meta- morphosis, and secretion from skin, kidneys and bowels. We also find that structural lesions are influenced in the same manner. Inflammation is active in propor- tion to increased temperature, as is also the tendency to suppuration and death of the part. The influence of zymotic causes of disease is also increased in tho ratio of increase of temperature, and the condition known as typhoid is marked in proportion to it. In surgical disease we find the processes of repair arrested when the thermometer marks 103° ; above this the pus loses its laudable character, becomes thin, ichorous, etc., and presently the structures soften and break down. The fact that increase of temperature is a condition 1<)6 STUDY OF DIAGNOSIS. in many chronic diseases has already been noticed. In phthisis pulmonalis the first advent of disease is an- nounced by a temperature of 100°. In morbus coxa- rius, white swelling, etc., increase of temperature is one of the most pronounced and distinctive symptoms. In all these cases we may say that the rapidity of dis- ease is in the ratio of increased temperature, and so long as the temperature is thus high no amendment need be expected. If the temperature can be reduced and maintained at or near the normal standard, the de- structive processes are less active, and a cure rendered possible. If we decide that a wrong of the temperature is a cause rather than a result, even though but in part, we wish to know the means by which it may be rectified. The first proposition — " as is the pulse so is the tem- perature " — gives us the use of the very important class of remedies — the special sedatives. If these rem- edies exert a direct influence in giving a slower and better circulation, they will also lessen the temperature. Certain remedies especially influence the temperature through the nervous system, as Ehus, Gelseminum, Bryonia, Belladonna, Nux, Nitric Acid. Others influ- ence it through the constitution of the blood, as alka- lies, acids, food, etc. Then again we look to the skin as the regulator of heat in the body. It is possible that a wrong in the condition of this apparatus is the cause, in whole or part, of this lesion. What is the condition of the skin ? Is it dry, constricted, full, relaxed ? What remedies, in the form of baths, or otherwise, will right these wrongs ? If we take the simple lesion of excess of temperature STUDY OF DIAGNOSIS 167 and frequency of pulse, as seen in febricula, we will find a cure in the cold wet-sheet pack, as we would in the early stages of a sthenic inflammation. Or in place of this the ordinary vapor bath or spirit-vapor bath might be employed. In many cases with a diy and constricted skin the sponge baths are found to place this organism in better condition, and lessen the tem- perature. If a bath is medicated, we select it as we would the internal remedy. If an alkali is indicated internally by pallid mucous membranes, it will be found best for a bath. If an acid is indicated internally by deep colora- tion of mucous membranes, we will employ an acid bath. If the skin is relaxed and enfeebled, we think of stimulant, tonic, or astringent baths. We employ fatty inunction in two conditions — when the skin is dry and constricted, and when it is relaxed and enfeebled — in both the inunction answers a good purpose. In some cases w r e combine with it a stimulant, or one of the essential oils ; in others we make it a vehicle for the topical application of Quinine. If the increase of temperature is associated with waste of tissue, we find it important to provide a better fuel for burning, and thus allay the excitation caused by destruction of tissue. Thus in chronic disease we think of Cod Oil, and foods that contain calorif'acient material in excess, and that are at the same time easily digested. In acute disease we furnish similar kinds of food, whilst at the same time we modify the process of combustion as much as possible. In depression of temperature we find every function of life impaired, but in this case the lesion is always of depression, whilst in the preceding it was most fre- 168 STUDY OF DIAGNOSIS. quently of excitation. It requires but a slight fall of temperature to impair and finally arrest functional ac- tivity. With a depression of a single degree a man ia sick, and if this is maintained death will result in from two or three days to a week. In some cases of chronic disease we find a slight de- pression of temperature, as a part of the lesion. At once we ask the question, what is the cause ? Is it de- pendent upon want of food, or of proper food? A wrong of digestion ? An impairment of the respiratory function, and of the burning ? Or a wrong of the skin, so that it permits a rapid escape of heat? On the answer obtained to these questions, will depend the treatment. If it is a want of food, or of calorifacient food, a right treatment will look to the selection of appropriate kinds. If we find a lesion of digestion, either buccal, stomachic, or intestinal, means to rectify these lesions will be demanded. If it arises from deficient respira- tion, Ave will direct such exercise as will call into activ- ity the respiratory function, and facilitate comb.ustion. It is possible there may be a defect in certain materials that favor combustion. Thus in some cases I have found the want to be of Phosphorus, and its administra- tion at once restored the calorific function. In others it may be of Sulphur, or of Soda, or in some cases it would be met by Cod-Oil. Wrongs of the skin, per- mitting the escape of heat, are readily recognized by the touch, as evidences of relaxation, of exudation of water from the blood, or hyper-activity of the sudori- ferous glands. The remedies will consist of stimulant and tonic baths, or sometimes the use of fatty inunction with stimulants or with Quinine. STUDY OF DIAGNOSIS. 169 An irregular or unequal distribution of heat is a source of trouble as well as its increase or diminution. If we have too much heat in one place and too little in another, we will find associate wrongs of circulation and innervation, and there will be impairment of digestion, blood-making, nutrition, waste, retrograde metamor- phosis, and excretion. Wrongs of the blood are like- wise increased, and there is the tendency to deposits of imperfectly formed albuminoid material. Local dis- eases are also more severe, and the tendencj 7 to struc- tural changes more marked. In chronic disease we will frequently find that no im- provement takes place until the wrong of temperature is rectified. Getting well may hinge on getting the feet warm. With cold feet, remedies which seem adapted to the case, continually fail ; warm the feet, even by sprinkling Capsicum in the stockings, and the patient improves at once. In some of these cases topi- cal means will be all-sufficient, but in others we will have to employ such as give strength to the circulation and improve innervation. In acute disease unequal temperature is one of the most unpleasant symptoms met with, and it is always looked for in the advanced stages of severe disease. The experienced physician examines the patient's toes, his knees, his ears, the tips of his fingers, with as much interest, as he examines the pulse. If he finds coldness of these parts, he is at once awake to the necessity of every means for the conservation of life, whether it has reference to means to prevent undue expenditure, or such as will increase the forces of the body. Cold- ness of parts distant from the heart at once suggests the idea of alcoholic stimulants as food, to be supple- 15 170 STUDY OF DIAGNOSIS merited, as soon as may be by such foods as seem best adapted to the case. Changes of kind in temperature will not be recog- nized by the thermometer, and hardly by the physician who prides himself on being " scientific." " Kinds of heat indeed ! there is but one heat, and it is nonsense to try to make a distinction in kind " (?) This is all very well, but the practiced physician knows that there are kinds, at least in so far as his sensations are concerned, and that these " kinds " tell him of definite lesions, and point to remedies. We do not know just why we have varying sensations of kind, but we do even in warming apparatus. The sensation of heat is not the same from a coal stove, an open fire, hot water pipes, or a Dutch earthen-ware oven. And the sensation of heat by the hand is not the same in simple febricula, remittent fever, typhoid, typhus, yellow fever, scarlet fever, etc. The kind is unmistakable, and becomes more and more so as the wrong of the blood and of the nervous system increases. If one applies the hand upon a surface from which a sinapism has been recently removed, a peculiar sense of " pungency " is experienced. Quite as distinct a sensation comes in severe scarlet fever, in malignant rubeola, and in diseases characterized by the symptoms known as typhoid. We get a similar pungent heat when there is great excitation of the sympathetic and spinal nervous systems. We may say then, that this character — pungent heat — which is so readily recog- nized by most persons, refers us to lesions of the blood — sepsis, and to lesions of the nerve centres — excitation. We at once think of antiseptics as appropriate reme- dies, and select the particular one by symptoms already STUDY OF DIAGNOSIS. 171 named. In so far as the nervous lesion is concerned, we will be guided in the selection of remedies by the facial expression and by the pulse. It is possible many times, to determine the character of a local lesion by the sensation given the hand. Thus one very readily recognizes the peculiar pungent heat of erysipelas, and sometimes the touch will determine the advent of this lesion in surgical disease before the eye would recognize the change of color, or the intu- mescence of tissue. The hand placed upon the abdo- men will feel the advent of puerperal inflammation before it will be recognized by ordinary symptoms. There is very much to be learned in this regard, and it is well to give it thought and experiment. DIAGNOSIS BY THE EAK. The ear may not be as important in diagnosis as the eye or touch, yet we purpose employing it to its fullest capacity. To the routine physician who asks questions and depends for his knowledge of disease upon what the patient tells him, it is the organ of greatest impor- tance. But we have already seen that we do best when we study disease with our senses, and depend but little upon what the patient says. If the reader will refer back to our study of facial expression, he will notice the statement that wrongs of life find expression through the usual channels of ex- pression ; where the nerve currents have been most in the habit of flowing in health, they incline to flow in disease. Mankind use the facial muscles to express their feelings or sensations, and hence disease is ex- 172 STUDY OF DIAGNOSIS. pressed in the face. For the same reason we should expect to find wrongs of life expressed m the voice, in all animals using the voice, and especially in man who finds it a principal instrument of expression.* *The character of the human voice, under the influence of various emotions, has been discussed by Mr. Herbert Spencer in his interesting essay on Music. He clearly shows that the voice alters much under different conditions, in loudness and in quality, that is, in resonance and timbre, in pitch and intervals. No one can listen to an eloquent orator or preacher, or to a man calling angrily to another, or to one expressing astonishment, without being struck with the truth of Mr. Spencer's remarks. It is curious how early in life the modulation of the voice becomes ex- pressive. With one of my children, under the age of two years, I clearly perceived that his humph of assent was rendered by a slight modulation strongly emphatic; and that by a peculiar whine his negative expressed obstinate determination. Mr. Spencer further shows that emotional speech, in all the above respects is intimately related to vocal music, and consequently to instrumental music; and he attempts to explain the character- istic qualities of both on physiological grounds, — namely, on " the general law that a feeling is a stimulus to muscular action.'' It may be admitted that the voice is affected through this law; but the explanation appears to me too general and vague to throw much light on the various differences, with the exception of that of loudness, between ordinary speech and emotional speech, or singing. That the pitch of the voice bears some relation to certain states of feeling is tolerably clear. A person gently complaining of ill-treatment, or slightly suffering, almost always speaks in a high-pitched voice. Dogs, when a little impatient, often make a high piping note through their noses, which at once strikes us as plaintive, but how difficult it is to know whether the sound is essentially plaintive, or only appears so in this particular case, from our having learnt by experience what it means! Kcngger states that the monkeys ( Cebus azara;), which he kept in Para- STUDY OF DIAGNOSIS. 173 As we come into the sick room we give attention to the voice of the sick person, quite as much as we do to what he is saying. We find that it expresses strength and weakness, is free or difficult from local disease, and shadows forth the condition of the brain in its tone, which varies from the listlessness of atony to the quer- ulousness of excited feebleness, and the excitation of over activity. In studying the voice as the expression of disease, we recognize its three-fold bearing as it refers us to a general impairment of life, a lesion of the brain, and to lesions of the respiratory apparatus. If we did not keep these sources of wrong in view we might make serious mistakes. If, for instance, we have feebleness of voice, it may be due to general impairment of life, to impairment of the functions of the brain, to deficient innervation from the spinal cord, or to a lesion of the respiratory apparatus. Whilst strength of voice is usually regarded as evi- dence of good vital power, and a good respiratory ap- paratus, it will not do to place too much dependence guay, expressed astonishment by a half-piping, half-snarling noise; anger or impatience, by repeating the sound hu hum a deeper, grunting voice; and fright or pain, by shrill screams* On the other hand, with mankind, deep groans and high piercing screams equally express an agony of pain. Laughter may be either high or low; so that, with adult men, as Haller long ago remarked, the sound partakes of the character of the vowels (as pronounced in German) and A ; whilst with children and women, it has more of the character of E and /; and these latter vowel-sounds naturally have, as Helmholz has shown^ a higher pitch than the former; yet both tones of laughter equally express enjoyment or amusement. — Darwin. 174 STUDY OF DIAGNOSIS. upon it in these regards. It certainly evidences good innervation from the brain and spinal cord. But if these nerve centres are sound, active, and well supplied with blood, we may have a strong voice, even though the body at large is nearly exhausted. Usually it is a favorable symptom. Feebleness, on the contrary, evidences a lesion of atony, either of the body at large, of the brain or mind, of the spinal cord, or of the respiratory apparatus. Whilst the probabilities are in favor of its being a nervous lesion, we will not take it for granted, but make such examinations as will localize the lesion. Feebleness simply, without querulousness, suggests the use of Phosphorus, the Hypophosphites, Cod Oil, Alcohol as food, Iron, Arsenic, Quinine. If it is associated with a marked effort from the will, and a sighing respiration, we refer it to deficient innervation from the spinal cord, and think of Strychnia, Ergot, or Santonine as reme- dies. In lesion of the respiratory apparatus there will be change in the voice other than feebleness. It is difficult to give a name to the peculiar expres- sion of voice associated with nervous irritation and vas- cular excitement, yet the reader will learn to recog- nize it readily, and may frequently be able to deter- mine these characters of disease by simply hearing the patient speak. There is a sharpness, and want of smoothness, representing pretty accurately in degree the amount of disease. The halting voice, evidencing a labored action of the brain, tells the story of congestion, and suggests the use of Belladonna, or if markedly halting, of Lobelia. The oppressed voice, hollow and unsteady, evidences a general impairment of life, and calls for stimulants, tonics and food. STUDY OF DIAGNOSIS. 175 The oppressed voice from the upper part of the lungs suggests deficient innervation to heart and respiratory apparatus, and causes us to think of stimulant doses of Lobelia. Sharpness of voice suggests nervous excitation, and will sometimes point to the remedy, as in the peculiar sharp accentuation of the Rhus voice, resembling the cry cncephatlque of the child. The cry of the child will frequently inform the phy- sician of the location and character of the disease. Of course we recognize the fact that there may be but little change in the ciy, or that there may be changes without corresponding disease, but we have other means of diagnosis to supplement this, and prevent error. Physicians who have given this subject atten- tion will recall the peculiar cry of abdominal distress, the change which marks disease of the respiratory ap- paratus, the oppressed cry of congestion, the shrill, metallic cry of inflammation of the brain, etc. It does not take much observation to distinguish the cry of disease from the cry of hunger, or anger. In the preceding paragraph a peculiar cry, encepha- Uque, was noticed, which is so distinctive that it will never be mistaken. Its suddenness and shrillness is characteristic. In its slighter forms it arises from cere- bral irritation and determination of blood, and calls for Gelseminum as the rernedj\ When marked and shrill, I should always think of Ehus Toxicodendron as the remedy. A sudden cry, followed by sobbing respiration, is a prominent indication for Bromide of Ammonium. The voice is the function of the larynx, and its changes will point us to disease of this organ. The 176 STUDY OF DIAGNOSIS. croupous cry and voice is quite as distinctive as the croupous cough. If it evidences moisture, we have mucous croup; if it is dry and metallic, pseudo-mem- branous croup; if variable in tone and character, spas- modic croup. In chronic disease of the larynx, roughness of the voice is one of the first symptoms. As the disease pro- gresses, we have various changes in the voice and dif- ficult use of it, as characteristic symptoms. In chronic bronchitis we also find change, but not similar in kind. It may give the voice shrillness, as in irritative bronchitis, or dullness, hollowness, or rever- beration, as in asthenic bronchitis. Cough. — Whilst cough calls our attention to a prob- able disease of the respiratory apparatus it does not in- dicate with any certainty the character of the disease. But even to this extent it is important, for it is possible to overlook local disease, from the prominence of gen- eral symptoms. Whilst cough is usually the expression of diseaso of the respiratory apparatus, it may have its origin in other diseases. Thus we find cough from gastric, biliary and intestinal lesions, and from disease of the nerve centres, and our examination is made with reference to these probable causes in obscure cases. Cough is the expression of irritation, and comes from the sense of an irritant material in the respiratory pas- sages, which it is intended to remove. But many times there is nothing to be removed — it is a misconception of the respiratory nerves, which suffer from irritation, and we wish to determine whether or not the effort is to be favored. In the larger number of cases expccto- STUDY OF DIAGNOSIS. 177 ration is undesirable, and if we remove the irritation of the nerves the cough ceases. A little attention upon the part of the physician will determine this point, as it is quite easy to distinguish the cough necessitated b} T increased secretion, and at- tended by expectoration, from the inefficient, rasping cough of irritation. In either case, but especially in the last, an effort of the will is of marked benefit in checking cough. The character of the cough expresses to some extent the condition of the respiratory passages. If dry, ringing, metallic, we think of irritation, determination of blood, and arrest of secretion, and the remedies at once suggested are those which allay irritation, check determination of blood, and favor normal secretion. If moist, rattling, gurgling, dull, stimulants to the res- piratory passages, as well as remedies to relieve irrita- tion are suggested. A cough is more or less forcible, and more or less easily under the control of the patient. If forcible, not under control, or explosive, we at once suspect a wrong of the nerve centres, usually of the basilar brain, and select remedies accordingly. Of course we may have si'ich uncontrollable cough from local irritation, especially of the throat, but this will be readily recog- nized by the expression, as well as from the patient's sensations. A cough has more or less evidence of strength, both of the respiratory apparatus, and of the body at large. The strong, well sustained cough may be a source of annoyance, but evidences good vitality and a naturally good condition of the respiratory organs. A feeble cough, on the contrary, is the evidence of debility, and 178 STUDY OF DIAGNOSIS. at once suggests the necessity of care in the conserva- tion of life, and the employment of means which will give strength, especially the selection of proper foods. A cough may be feeble from deficient spinal innerva- tion, and spinal stimulants would prove the best reme- dies. Coughs are spoken of as short, hacking, deep, bron- chial, etc., and these characteristics may suggest the locality of disease. A short cough may arise from dis- ease of the upper lobes of the lungs, or it may be due to disease of the parenchyma of the lung, as in the first stage of a pneumonia. The hacking cough evi- dences irritation of the respiratory nerves pointing in the throat. The deep or bronchial cough is at once referred to lesions of the bronchial tubes, though it is not as good evidence as we would wish. A cough niay have its origin in irritation of any part of the respiratory apparatus, from the pharynx, larynx, trachea, bronchial tubes, parenchyma of lungs, to the pleura. As named above, its character may suggest the seat of disease, but as a rule, it is not definite. A sin- gular thing about coughs is, that the irritation points so that many times the patients can localize the sensa- tion of irritation for us. Cough very frequently points in the pharynx, and the irritation of the throat seems to be its direct cause ; such a cough is based to a con- siderable extent upon irritation of the respiratory nerves, and remedies directed to relieve this will be the best cough medicines. In other cases cough points about the supra-sternal notch, and if very severe and persistent suggests the use of remedies which influence the sympathetic nervous system, as Veratrum, Bryonia, Cactus, Pulsatilla. STUDY OF DIAGNOSIS. 179 Coughs may be spasmodic and paroxysmal, even in severe cases, showing distinct, epileptiform symptoms. Whooping cough is the typical spasmodic cough, but we have in the cough of measles, and some diseases of the respiratory apparatus, the same characteristics. It suggests Drosera, Belladonna, and Bromide of Ammo- nium. PHYSICAL DIAGNOSIS. Diseases of the respiratory organs and the heart are diagnosed in part by an exploration of the chest with the ear. Whilst an examination of the chest with the e}^e and the touch will determine something of the character of disease, and direct our attention to reme- dies, our reliance will be placed principally upon what we hear. In the case of the respiratory organs, a very import- ant part is to determine the capacity of the lung for air, or the amount of air contained in the chest, and this is accomplished by percussion. The walls of the chest are thin and elastic, whilst the lung which fills it contains normally four or five times as much air as there is of solid substance. Any elastic body contain- ing air will give resonance when struck, and the reso- nance will be in proportion to the amount of air. Lessen the amount of air, replacing it with a solid or fluid, and dullness of sound is the result. The object of percussion then, in diseases of the re- spiratory organs, is to determine the condition of the parencl^ina of the lungs with reference to capacity for air. By examination of the healthy thorax we obtain a standard of normal resonance for different parts of 180 STUDY OF DIAGNOSIS. the chest, and this we use as a basis for comparison. In many cases, but one side of the thorax being in- volved in disease, a comparison is instituted between the sound and the diseased side. In such cases, of course the information is more accurate, as we have the normal standard of resonance before us. Percussion is either direct or mediate, as we strike directly upon the wall of the chest, or interpose some- thing between. Direct percussion may sometimes be employed with advantage, using one or two fingers to give the blow. The only objection to this method is the unpleasantness to the patient, and the difficulty of making percussion of the intercostal spaces. In medi- ate percussion an ivory or rubber plate (pleximeter) is sometimes employed, using the finger for the stroke, or a small mallet of similar materials. The best method, however, is to apply one or two fingers accurately to the wall of the chest, and use the middle finger, sup- ported b} T the ring finger and thumb to give the stroke. It is necessary to use care in this, the fingers of the one hand being accurately applied to the chesty and the stroke being at right angles, and the muscles of the hand held firmly so as to give a quick rebound. As the object to be determined is the capacity of the lung for air, we make percussion both during full in- spiration and after expiration. In examining the mar- gin of the lungs over the false ribs and the sternum, it is necessary to have the patient take a full inspiration to carry the lung down to the insertion of the diaphragm in the one case, and to the mesial line in the other. In making percussion over muscles it is well to put the body in such position that the muscles will be rendered tense. In examinations about the shoulder, it is raised i STUDY OF DIAGNOSIS. 181 to allow our examinations to be carried up in the axillary space, or thrown forward or backward, to enable us to reach the upper part of the chest. In making comparison between the two sides, we are careful that there is the same degree of inflation, and it is better to have the patient take a full breath, and hold it as long as he can conveniently, or cease respiration for a moment, after the air is thrown out. Normal resonance tells us that the parenchyma of the lung is free from .effusion, it may be the seat of irri- tation, but the capacity for air is not interfered with. Increased resonance in slight degree is heard when the function of one lung being impaired, the other does an increased work. In greater degree it is the evidence of emphysema. When very marked, and over a lim- ited portion, it is the evidence of a cavity. Dullness on percussion evidences that the air is re- placed by a solid or fluid ; as is the degree of dullness, so is this change in the physical condition of the lung. We have dullness in acute pneumonia commencing about the third day, sometimes earlier, and increasing as deposit takes place in the air cells and intercellular passages, and in the connective tissue — as is the dull- ness, so is the intensity of the disease. Resonance returns when the circulation is restored, and effused materials are absorbed. Dullness is also an evidence Of chronic inflammation of the lungs, being usually much more extensive than in phthisis pulmonalis, for which it might be mistaken. Dullness on percussion, is heard in phthisis, when the tubercle is deposited in consider- able quantit} r and near the surface. In the earlier stages the dullness is so slight that it is not an import- ant evidence of disease. 182 STUDY OF DIAGNOSIS. We have dullness on percussion where there is fluid in the pleural cavities, whether it is simply of water, or the products of inflammation. In this case the dullness is of the most dependent part, and unless it is an ex- treme case, changing the position of patient, will change the situation of the dullness. Wc have dullness on percussion in hydropericardium, and to a limited extent in hypertrophy of the heart. The situation of the dullness, and the change in the sounds from the heart, will determine the condition of disease. Occasionally we have dullness on percussion from the formation of a thoracic aneurism, and still more rarely from growths in the cavity of the chest. Other symp- toms will determine the character of the wrong. The reader will notice that in acute disease dullness on percussion has reference mostly to effusion into, and solidification of the parenchyma of the lung. The ex- tent of the dullness determines the amount of tissue involved, and its intensity determines, to some extent, the severity of the lesion. In so far as it suggests treatment, it would say — lessen irritation and determi- nation of blood to the lungs — give the respiratory appa- ratus rest — by appropriate food, and in so far as medi- cines act to sustain the life of the part, and of the body at large — and by the establishment of secretion, promote the absorption of the effused material. Percussion is sometimes employed in other parts than the thorax to give evidence of disease. Thus we find that some wrongs of the stomach, of the liver, spleen, bowels, and reproductive apparatus, give rise to changes in the sound? heard on percussion. Disease of the stomach with generation of gas, will STUDY OF DIAGNOSIS. 183 be evidenced by marked resonance on percussion over the stomach. In some cases of chronic disease, this condition is persistent, and the continually distended stomach is pressed upwards until it occupies consider- able space, and resonance might lead us to suppose that a cavity had formed in the inferior lobe of the lung, had we not symptoms of gastric lesion, and the reso- nance extending across the epigastrium. On the right side an enlarged liver pressed upwards encroaches upon the cavity of the chest, and gives marked dullness on percussion over the right false ribs. The evidences of wrong digestion, and the fullness at the margin of the ribs will correct the diagnosis. In distension of the bowels by gas, we get the evi- dence of resonance on percussion. If of the small in- testine it occupies the anterior part of the abdomen; if of the large intestine it is lateral, or in the situation of the transverse colon. In ascites the small intestine distended with gas floats at the top, and though we get the dullness of water below, and succussion on palpation, there is resonance at the highest part, if the convolutions are free to move. In ovarian dropsy, on the contrary, the sac displaces the small intestine as it grows, and either crowds it upward or backward. Intestinal resonance on the surface, in dropsy, is therefore one of the differential points in distinguishing between ovarian disease and ascites. We employ palpation to determine the presence of fluid, whether in the cavities, or formed by the break- ing down of tissue. In some cases the evidence of fluctuation is very distinct, the wave of fluid passing 181 STUDY OF DIAGNOSIS. distinctly from the hand on the one side, to the hand on the other. In other cases, we only obtain a sense of mobility and the elasticity of fluid. When parts give rise to sound in the performance of their functions, the character of this becomes evidence of disease. This is the case with the respiratory appa- ratus, the heart, and to a less extent with some other parts. Listening to sounds thus produced is called ausculta- tion, and as practiced may be either direct or mediate. In direct auscultation, the ear is applied to the part, and the sounds heard. In mediate auscultation, an instrument called a stethoscope is employed as a con- ductor of sound. I prefer direct auscultation, as we desire to hear the exact sounds produced, neither intensified nor modified. It is quite as easy to apply the ear as a stethoscope, and except in some rare cases of cutaneous disease there is nothing objectionable in such examination. It is claimed that female modesty might be shocked by this direct examination, both of the chest, and especially of the lower abdomen to detect the beatings of the foetal heart. But I confess that in my professional life I have met with but little of this mock modesty. The special value of the stethoscope is the impression it makes upon the public. In the olden time the ph}- sician carried a gold or ivory headed cane, or rather a staff, to give him an appearance of dignity, and the professional pose, as shown by Hogarth, with the head of the cane pressed against the nose or forehead, in profound thought, is a fair representation of the dig- nity " that pays." As the physician's cane has gone out of fashion, the stethoscope, and instruments of STUDY OP DIAGNOSIS. 185 similar kind earne in to sustain the dignity of the pro- fession. Stethoscopes are made in varied forms, from the sim- ple short wooden cylinder (with a hole through it) to the double ear-tube instrument of Camman. Some are bo illy adapted to their use, that scarcely anything can be heard, except the unpleasant roaring from ill adap- tation to the ear. The best stethoscope is a simple cylinder of solid wood, with the one end adapted to the walls of the chest, and the other to the physician's ear. It may be long or short, or have any shape the taste of the maker may give it, if it possess the characters named, it will answer its purpose well. In the practice of auscultation, whether direct or with a stethoscope, the physician is careful to avoid adventitious sounds, and to place his body in a conve- nient position for listening. The rubbing of clothing, either upon itself, or against a stethoscope, will fre- quently mask the sounds we wish to hear. A con- strained position of body frequently interferes with listening. In auscultation of the chest in health two respiratory sounds are heard — the respiratory murmur, and the bronchial sound. The first is heard during inspiration and expiration over the entire surface of lung ; the second is heard by applying the ear over the spinal column from the middle cervical region to the sixth dorsal vertebra — the spinal column being a good con- ductor of sound. If the normal respiratory murmur is heard we know this portion of the parenchyma of lung is healthy ; if it is changed in character, or re- placed by adventitious sounds from the air cells and email passages, we know that there is disease. 16 l86 STUDY OF DIAGNOSIS. Id studying auscultation, it is well to study in the language most familiar to us. If we are original Eomans we may pursue the study in Latin ; if French, we may use French technical terms; but if English is our mother tongue, we had better e m pi oy English, and use words with especial reference to their meaning. I think it is possible to so classify and name the morbid sounds that the reader can learn them without trouble. We may say first, that a wrong sound made in the respiratory apparatus is evidence of disease of this apparatus. We want then to determine the value of the sound, and the distinct lesion that produces it. To this end, the first question is as regards the medium for the conduction of sound. Solids conduct sound best, fluids next best. Air stands next as a con- ductor, and mixed bodies last. The lung, with its spongy tissue filled with air is a bad conductor of sound. If it is solidified, it becomes a good conductor, and sounds will be heard, which otherwise would not reach the ear. Fluids compressing the lung are also good conductors of sound. To determine this point, then, percussion is made — if there is resonance the sound is referred wholly to a wrong of the part where it is produced ; if there is dullness on percussion, it is referred in considerable part to the consolidation of lung, or to the effusion, which gives a better conductor of sound. Morbid sounds may be divided first into blowing and crepitant, having reference to the parts in which they are produced. Blowing sounds are produced in bron- chial tubes, and crepitant sounds in the intercellular passages and air cells, Blowing sounds are blowing. The idea the listener STUDY OF DIAGNOSIS. 187 gets is of air blown through a tube possessing some elasticity. In the blowing sounds heard in diseases of the respiratory apparatus, the listener gets an idea of obstruction ; the air does not pass as freely as in health. In one case the sense is of constriction — evidently the calibre of the tube has been diminished— the sound has the higher tone or shrillness that would be thus pro- duced. In another case the obstruction is evidently within the tube, either from fullness of mucous mem- brane, or from increased secretion, and the sounds are lower in tone — duller — or show the evidence of mucus in more or less of gurgling. In a third class of cases, the obstruction is evidently from want of elasticity and tone in the tube, which yields before the passage of air, both in inspiration and expiration — the wavering tone of the sound determines this condition. In so far then as we have analyzed the simple char- acter blowing, we have suggested to us a rational prac- tice of medicine. Contraction of bronchial tubes is in the majorit}^ of cases from irritation — employ those remedies which take away the irritation. Fullness of mucous membrane suggests the use of means to relieve determination of blood, and to promote absorption Increased secretion suggests the employment of means to take away irritation and determination of blood, and check secretion. Whilst the wavering sound indicating atony, calls for stimulants, tonics and restoratives. Blowing sounds are dry and moist, and these common words express clearly the idea formed upon hearing the sounds. They are dry and moist, as they refer to a condition of dryness or moisture of the mucous lining of the bronchial tubes. Dry blowing sounds evidence a condition of bronchial 188 STUDY OF DIAGNOSIS. tubes in which there is an impediment to the free passage of air, and more or less arrest of the normal mucous secretion. Dryness itself is an impediment to the passage of air, but in addition there is contraction of the bronchial tubes. We are in the habit of saying — as is the blowing, so is the contraction of the tubes — as is the sound of dryness, so is the arrest of secretion. Contraction of bronchial tubes results from irritation, and it suggests that such means be employed as will relieve irritation. Dryness results from irritation, de- termination of blood, and the developed inflammatory process. Given a dry blowing sound, we at once think of general and local sedatives which lessen determina- tion of blood, remedies which "allay irritation, remedies which so rectify general lesions of circulation and tem- perature as to permit secretion, and remedies which restore secretion, if such be necessary. Thinking in straight lines, our ear gives us information of the con- dition of the air passages, Ave at once think of the pathological states, and having the factors of disease before us, we at once think of those remedies which restore normal functional activities. Moist blowing sounds tell us of obstruction to the free passage of air, and to the pressure of fluid in the air passages. As is the blowing so is the impediment to the passage of air ; as is the moisture, rattling, bub- bling, gurgling, so is the amount of fluid in these pas- sages. The ear readily determines from the character of the sound, whether the blowing is still due to contraction of the tubes, for in this case the sound is steadier and more resonant, than if caused by obstruction from accu- mulated fluids, or from atony. The well-sustained, STUDY OF DIAGNOSIS. 189 sonorous sound always means contraction — contraction results from irritation — use remedies to lessen or take the irritation away. The impediment from secretion of mucus, muco-pus, or purulent fluid is clearly expressed in the sounds heard, and it is well to take the evidence of the ear, rather than any technical classification of sound. The presence of just sufficient secretion to lubricate the passages, of occasional accumulations which need re- moval by expectoration, of continued accumulation, giving rise to rattling sounds like the bursting of large bubbles, or the gargling which comes from large quan- tities of fluid, are distinct and unmistakable. The treatment is clear — take away the causes of determina- tion of blood, whether due to irritation of the respira- tory nerves, or some general lesion. Give these tissues such support as we can, by the use of remedies that give local or general stimulus and tone. And to a cer- tain extent favor the removal of these accumulations by expectoration — usually by giving strength to the respiratory apparatus. The evidence of atony of the respiratory passages is found in the yielding or tremulous character of the sound. Whilst the evidence of contraction was found in the well sustained sound, this is found in the feebly sustained sound. The treatment is clear — to sustain and increase the strength of the patient, and to stimu- late and strengthen this enfeebled organism. In some cases alcoholic stimulants give prompt relief, and their effect is maintained by Quinine, restoratives, and food. The local remedy is Lobelia in stimulant doses, and we always think of this, especially in infancy and child- hood. 190 STUDY OF DIAGNOSIS. When cavities arc formed in the lung, communicating with a bronchial tube, the ear detects a peculiar blow- ing sound, as of air blown into a bottle. This may be dull and more or less gurgling, showing that the pro- cess of removal is not yet completed, and the walls of the cavity are of the spongy, partly broken down lung. Or it may be clear, well sustained, and more or less re- sonant, showing the removal of deposit, and cicatriza- tion. Small blowing sounds, varying in character, shrill, whistling, piping, irregular, tortuous, dry, moist, rat- tling, all combined, in varying proportions, are the best evidences of phthisis pulmonalis. If the reader will think for a moment of the structures involved, the situation of the tubercular deposits, how they must press upon the smaller bronchial tubes, changing their position, making them tortuous, changing their calibre, he will see at once that these are just such sounds as might be expected. In addition to these small, queer, blowing sounds, the ear detects that known as dry crackling. During a full inspiration three or four distinct crackling sounds are heard, which seem to the ear veiy much like the sounds produced by separating two surfaces attached by a glu- tinous fluid. And undoubtedly this is the condition, for if the tubercle is so deposited as by pressure against a bronchial tube to efface its cavity, the separation of the glutinous walls of mucous membrane would give just such sound. Crepitant sounds take the place of the respiratory murmur, and are formed in the air-cells, the intercel- lular passages, and the minute bronchial tubes. When ? therefore, small crepitation is heard, we refer it at once STUDY OF DIAGNOSIS. 191 to disease of the parenchyma of the lung. If we in- quire into the condition of the lung — the changes of structure that will produce such sound — we find it in irritation, determination of blood, and slight effusion into these minute air passages. If the effusion goes on, the lung is rendered impermeable to air, and the crepi- tant sound ceases. Crepitance is therefore the evidence of inflammation of the lung in its first stage, and is associated with re- sonance on percussion, for the disease has not pro- gressed to hepatization. Where effusion has taken place to the extent of giving dullness on percussion, the crepitant sounds are replaced by blowing sounds from the bronchial tubes, the lung being now a better conductor of sound. Larger crepitance refers us to the minute bronchial tubes, and is the evidence of capillary bronchitis. The smaller crepitance is not only heard in the first stage of an inflammation of the lungs, but returns with the absorption of the effused material, and resolution, and is therefore the evidence of the subsidence of the disease. As crepitance is the evidence of the active stage of an inflammation, in which irritation and determination of blood are the prominent factors, the treatment is plain. In so far as we can take away the irritation, and stop the determination of blood, our treatment will be rational. The frequent pulse, the high temper- ature, and the rapid respiration, are important elements in the furtherance of the local disease, and means which will rectify these wrongs, are of first importance. As the succeeding stage is one of local depression of life, no means should be emplo}-ed that will depress either the life in general, or of the affected part. v 192 STUDY OF DIAGNOSE, Where solidification of a lung has tciken place, it becomes a better conductor of sound, and if now the ear is applied and the patient is engaged in conversa- tion, the voice seems to come out through the chest. We do not get articulate speech, but simply the modu- lations of the voice. This is called bronchophony (speaking through the bronchial tubes), but its only value is to determine solidification of the lung, and per- cussion is the better evidence. If there is fluid in the chest, and the ear is applied over it, the patient conversing, the voice seems to come out through the chest, but has a tremulous tone. This has been called segophony, and is one of the evidences of fluid in the pleural cavities. If the ear is applied over a cavity, which is free and communicates with a bronchial tube, and the patient is engaged in conversation, the articulate voice comes to our ear through the chest. This is called pectoriloquy, and is additional evidence of the formation of a cavity in the lungs. In some cases of structural disease of the pleura, the result of inflammation, certain friction sounds are heard, but they are not very common, distinct, or defi- nite. Once in a while they are said to assume the dis- tinctness of the u creaking of new leather," but in the two cases I have seen, the sounds were evidently from wrong of the parenchyma of the lung, and not from the change of the pleura. We employ auscultation in the examination of the heart with as much advantage as in diseases of the respiratory apparatus. As the sounds produced by the heart are much louder, and more distinct or arbitrary, many persons will succeed better in auscultation of the heart, than of the lungs. STUDY OF DIAGNOSIS. 193 The normal sounds of the heart are smooth, uniform m tone, regular in time, and give the ear an agreeable sensation. Ko description in words would give the reader a sufficient knowledge of them; they must be heard to be thoroughly known. It is hardly worth while to call the reader's attention again to the impor- tance of knowing the phenomena of life for himself, and especially with regard to things that may so easily be known by the senses. If, in examination of the heart, we find that the sounds are normal, we are quite sure that there is not structural disease of this organ. If there are general symptoms of heart disease, the wrong is functional. If, on the contrary, the sounds of the heart are changed, or replaced by adventitious sounds, we are just as sure that there is structural disease of the organ. The two exceptions to these rules are : — 1st, in case of anaemia or spansemia, we hear blowing sounds, which are re- ferred to the wrong of the blood, and not to the heart ; and 2d, in fatty degeneration, no change in the sounds of the heart announce the structural lesion. The morbid sounds of the heart may be divided into blowing and sawing, and the ideas conveyed by these words represent exactly the character of the sound. Whilst blowing sounds may be referred sometimes to lesions of the walls of the heart, and a wrong in mus- cular contraction, the sawing sounds are referred to the openings of the heart, and to the valves, and usually to lesions that obstruct the free flow of blood. The blowing sounds have been named bellows mur- murs, and have every range between the simple, smooth, blowing sound, similar to that heard from the bronchial tubes, to the roughened, irregular, rattling 17 194 STUDY OF DIAGNOSIS. sound, similar to that produced by a pair of bellows in motion. If the sound is dependent upon poor blood, it may many times be heard over the larger arteries as well as the heart, and in this case will call for the proper restoratives and food to make good blood. If dependent upon enfeebled nutrition, or degeneration of the walls of the heart, we employ means to give the heart rest, see that it is not subject to excitement, and employ means to improve nutrition. The rough, irregular sound that is attributed to valvular insuffi- ciency and regurgitation, would demand the same treatment. The saw sound has been divided into three varieties, the saw, rasp and file sounds, but the distinction has but little reference to conditions of disease, or to the use of remedies. Possibly the finer sounds may refer us to a more acute condition of disease, in which plastic material is yet being deposited. In some cases of val- vular insufficiency we hear a marked saw sound, but it has an irregularity and dullness that we do not meet with in the other cases. The more common lesions that give rise to contrac- tion of the openings of the heart, and such disease of the valves as prevent their free movement, are inflam- matory, and give fibrinous exudation as the result. The most of these are rheumatic in character, involving the tendinous portions of the muscle, and the endo- cardium. There are rare cases in which the sounds are due to fibrinous vegetations from the valves, or to ossific deposit in their structure. The treatment suggested by these sounds has refer- ence, first to rest, and secondly, to means which will promote absorption, and give us a better renewal of STUDY OF DIAGNOSIS. 195 life. Eest is absolutely essential to recovery from chronic inflammation and the absorption of its pro- ducts. We want physical rest, and mental rest, and such relief from irritation of the cardiac nerves as may be obtained from the use of Cactus, Pulsatilla, and the special sedatives. Eemoval of deposits is facilitated by the establishment of free secretion, and a better heart is made by means to obtain good blood, and good nutrition. To determine pregnancy after the fifth month the ear is applied over the lower abdomen to hear the beat- ings of the foetal heart. If it is heard the diagnosis is clear, but if not, we are not yet certain that pregnancy does not exist, for in many cases, from feebleness of the movement of the foetal heart, excess of liquor amnii, thick abdominal walls, or the position of the child, it can not be heard until late in pregnancy, or not at all. DIAGNOSIS BY THE SENSE OF SMELL. The sense of smell has less development in the majority of men than any other of the senses — as some writer has recently remarked — " it is yet in the savage state." It may not be of much use in diagnosis, and yet the little it may tell us we want to know. It requires education, as do the others, and we must learn to dis- tinguish pleasant odors from stin7ts, and thus be able to analyze stinks, and determine their influence upon the human body. It is possible that some persons will never be able to recognize the genus " stink," much less be able to assort them for our present purpose. It is well for the physician to commence educating 196 STUDY OF DIAGNOSIS. his nose at home, and to start with a realization of the fact that all unpleasant smells are noxious to the human body. It requires very little exercise of reason to reach this conclusion, for if the thing was not unplea- sant or noxious to the economy, the nose would not give the warning of unpleasantness. What is the evi- dence of disease to the person suffering? Unpleasantness ; the very expression used, " persons suffering," tells the story of disease. Is disease ever pleasant ? No. Are causes of disease ever pleasant ? No. Do causes of disease ever pleasantly impress the senses? You might answer yes, but I say no again. Commencing at home I put my nose inside your office door, and — heaven preserve me — what a com- pound of stinks, from Asafoetida to Jalap, from Castor Oil to Turpentine. Lesson No. 1, true remedies have no bad odor, clean up j^our stinks and put them in the nearest privy-vault, and have a thorough disinfection. Eeason why — it will be money in your purse— people that paj^ good bills don't like stinks, as a rule. Let me nose your saddle-bags and pocket-case ? Faugh ! what a terrible sickly smell! — reminds me of the old country doctor, who was always announced by a mixed smell of Asafoetida and Jalap. It won't do in this age ; burn them up, and order a new stock. Now clean up your- self, and get your nose in good working order, that j^ou may learn diagnosis with it. Do you know how to eat onions and go-a-sparking too ? Have the maiden taste them. Eeverse the simile — if you cany bad smells about you, j*ou will not be able to detect them in the sick room — and it is a most important work, believe me. When I visit a sick room, my nose commences the inquiry, (it is a most excellent interrogation point). STUDY OF DIAGNOSIS. 197 What provisions have you made for fresh air, sunlight, and cleanliness ? It says straightway, the air is bad, there must be ventilation, and opens a window, builds an open fire, and does what is necessary. It noses a stink from under the bed, and suggests half cleaned chamber utensils, excreta, dirty clothes, dirtied floors, etc. It says with emphasis there must be a thorough cleaning up. The excretions muot be removed as soon as voided, the utensils thoroughly cleansed and disin- fected, every loose thing removed, the floor cleansed, the bed drawn from the wall, and so arranged that the air can pass freely under it. It says you have been trying to feed this patient upon stale, badly prepared food, and it detects it remaining in the room hour after hour, poisoning the atmosphere, and taking away what little desire the patient may have for nourishment. It says, the food for the sick must be nicely prepared, fresh and savory, at such times as he can best take it, and then promptly removed from sight or sense. It says — you are dirty — dirty in person, dirty in clothing, dirty in bed. You must be thoroughly cleaned up, washed with soap and water, have frequent changes of clothing and bed linen — " cleanliness is next to godli- ness." You can't hide dirty sheets from this nose, or a bed soiled by involuntary discharges, or a bed sore, a badly dressed w^ound, however you may try to cover them up. It recognizes the row of nasty medicine bottles, and says, "take them out" — your spoiled poultices and fomentations, and says, " fresh water." It tells you of damp walls, of lack of sunshine, of choked drains, of ground saturated with garbage, of foul closets, of cellars uncleaned, of decomposing vegetables, 198 STUDY OF DIAGNOSIS. and of the hundred and one noxious agencies which breed disease and steal away a man's life. But it not only tells you of dirt, and specifies clean- liness as the remedy, but it tells of specific agents to destroy causes of disease. I will warrant that you have already associated an unpleasant odor of decay with lime. Lime to freshen the air of cellar, lime to slush a bad drain or cess-pool, lime to make way for sunlight, and to get rid of the deatient, indeed his life may be destroyed by its presence with and around him. Variola. — The diagnosis of smallpox will be made by — a, the intense, aching pain in all parts of the body, deep seated, during the first day of febrile reaction ; b, the appearance of the eruption, as distinct red spots, Which give to the touch the sensation of hardness like a shot under the skin ; c, the regular development of the pustules in a period of nine days; and d, the flat- tened and umbilicated form of the pustules. It suggests protection by vaccination, by avoidance of the cause, by the use of proper antiseptics. In the treatment of the disease, that the contagion be removed, as far as possible, by the excretory organs, and at length by the completed stages of the eruption. When the contagious virus is in large quantity, as shown by the nsual evidences of decomposing animal matter, it suggests the use of antiseptics, agents that destroy the material of contagion, great cleanliness, and a sustain- ing treatment. Eubeola. — The diagnosis of measles will be made by — a, the catarrhal sj-mptoms, full, suffused and in- jected eyes, w T hich announce the attack; b, the pecu- STUDY OF DIAGNOSIS. 229 liar and constant cough ; and c, the irregular form of the eruption. It suggests Lobelia and Asclepias to favor the deter- mination of the eruption upon the skin, and relief of irritation of mucous membranes, and Drosera as the special remedy for the cough. Scarlatina. — The diagnosis of scarlet fever will be made by — a, the early appearance of a sore throat, which persists and is a marked feature of the disease ; 6, the high range of temperature, and dryness of sur- face ; c, the vivid scarlet redness of the eruption ; and J, the evident impairment of the cutaneous capillaries, as marked by the persistent white line left as the finger is drawn over the surface. It suggests Belladonna in minute doses as a prophy- lactic, Belladonna and Carbonate of .Ammonia as stim- ulants to the capillary circulation of the skin. And the use of fatty inunction alone, or with stimulants — Creosote and Common Salt. Varicella. — The diagnosis of chicken pox will be, made by — a, the irregular appearance of the points of eruption ; 6, their speedy development ; and c, their vesicular form. Pertussis — The diagnosis of whooping cough will be made by — a, the occurrence of cough without febrile symptoms ; 6, its parox}^smal and spasmodic character ; and c, the whoop, the sibilant or whistling sound as the air is forcibly drawn through the contracted larynx during or at the close of the paroxysm. It suggests specific remedies, Drosera, Belladonna. 230 STUDY OF DIAGNOSIS. Nitric Acid, and Trifolium Pratense, as may be indi- cated in each case by special symptoms. Zymotic Disease. — Whilst all contagions may bo classed as zymotic, all zymotic diseases are not conta- gious. Those named — erysipelas, diphtheria, spotted fever, and cerebro-spinal meningitis — maybe epidemic, endemic, or contagious, and we study them in each of these classes. When they prove contagious, it may be from either of two conditions — the intensity of the dis- eased action, or the loss of life and breaking down of the tissues. If we take the first disease, erysipelas, we will find that it sometimes develops remarkable virulence in this direction ; so much so that it will attack almost every surgical case in a hospital, and will be contracted by nurses and others. This of course will be noticed espe- cially in certain years (epidemic influence) and in cer- tain localities (endemic influence), but we can not neglect to notice the contagious element. In the one case we notice the intensity of disease, both as to its local and general symptoms. The part is in- tensely hot, burning, painful, and is dry and tense, and its color, whether bright or dark, is vivid. The pulse is frequent, tense, and unyielding, the temperature has a high range, and the nervous system shows great exci- tation. Whenever such symptoms show themselves, we may fear contagion, and will employ means to pre- vent the infection of others. In the second case we have the evidences of sepsis and deliquescence of tissue. Locally the part is full, and wants elasticity, the epidermis yields, and presently the connective tissue The discharge becomes offen- STUDY OF DIAGNOSIS. 231 sive, the pulse oppressed and feeble, and the tissues at large softened. Whilst in the first case remedies would have reference to the intensity of diseased action, and consist princi- pally of the five specifics — Iron, Veratrum, Ehus, Apis, Belladonna; in the second it will consist in the use of the proper antiseptics, with restoratives and food. In the second, puerperal fever, we notice the same two elements of contagion, quite as marked as in erysipelas. But there is added a third, an infectious material thrown off from the reproductive organs. So marked and virulent is this, that it is readily communicated by the physician from patient to patient, even through an interval of days or weeks. It is not only thus infec- tious, but is intensely poisonous to the patient, and its re-absorption intensifies disease, and frequently leads to a fatal result. Having regard to tho means named in erysipelas, the physician gives especial attention to prevent the spread of contagion. In some cases this may be avoided by strict attention to cleanliness, change of clothing, and the use of antiseptics, as washing with a solution of Chlorate of Potash, Sulphite of Soda, Labaraque's Solution, or dilute Sulphurous Acid. To prevent re- absorption, we use great cleanliness, and the antiseptics just named. In diphtheria the contagious property seems to be developed more by the intensity of disease, than by devitalization of tissue and putrescence, and it is always well to use extra precautions when the febrile action and local inflammation are intense. But here as i n puerperal fever a specific infection is generated at 232 STUDY OF DIAGNOSIS. the point of local disease, and is readity communicable to others. This is so marked that the diphtheritic de- posit is readily inoculable, not only in the throat, but on almost every abraded surface. The knowledge of these facts will not only cause us to guard against the general conditions of contagion, as in the other cases, but especially against the trans- mission of the local infection by coming in immediate contact with the patient and inhaling the breath, the use of towels, handkerchiefs, before they have been thoroughly purified b}^ boiling, and especially the use of probangs, swabs, or surgical instruments that have been employed on a diphtheritic patient. In cerebrospinal meningitis and spotted fever we have the double element of contagion first named. The generation of the infectious material by intensity of disease, and b3 r loss of life in tissues, and putrescency. The same means will be employed as in the case of erysipelas, both to prevent the spread of contagion, and to protect the patient against the poison generated in his own body. Cholera. — Asiatic cholera might be studied in the class of epidemic diseases, as in the seasons of its prev- alence there is a marked epidemic influence, that shows itself in other diseases as well as this. But though we recognize this, the evidence that it is propagated b 4 y a specific contagion is too well proven to allow us to neglect it. Cholera advances on lines of travel, and renews its strength as it goes, going with people, being propagated by and in people. Gaining strength and virulence b}^ special combination of circumstances in its native country India, it takes passage by steamship STUDY OF DIAGNOSIS. 233 to Europe, from Europe to America, where it is dis tributed by railroad, steamboat and stage It is probable that the infectious poison is found prin- cipally in the excretions, and mainly in the dejections from the bowels, and the disease is especially propagated from them. If so, it points the physician to the neces- sity of especial care in the removal of the dejections, and that they be so disposed of as not to endanger others, either by their exhalations, or by contaminating the water supply. We diagnose an attack of cholera by— a, the great exhaustion that attends the first discharges ; 6, by the evidences of imperfect circulation and aeration of the blood, as seen in the bluish discoloration of the ex- tremities ; c, by the want of color in the faeces, " rice water"; d, by the marked enfeeblement of the circu- lation, and lowered temperature ; and e, by the exces- sive thirst, nausea and vomiting, and muscular cramps. Typhoid Feveb, and acute diseases assuming typhoid symptoms, usually possess the contagious element in slight degree. Yet in some cases we observe a remark- able development of this character which demands the attention of the physician. Typhoid is generally thought to mean asthenia, but it is better to think of it as having reference to sepsis of the blood. With the condition' of sepsis, comes the property of contagion, and under some circumstances this becomes marked. 1 think diseases called typhoid will be found to develop the character of contagion both from intensity of dis- ease, and from impairment of the life of tissue and putrescence. The most marked cases I have known were when there was great nervous excitation, tense 20 234 STUDY OF DIAGNOSIS. tissues, high temperature, and the sensation of pungent heat when the hand was applied to the surface. The other cases are distinguished by a peculiar sweetish cadaveric odor of breath, dark fetid faeces, and fetor of urine. Typhus Fever is markedly contagious, and may be wholly propagated by a specific contagion generated during the progress of the disease, and thrown off in the excretions both from bowels, kidneys, skin and lungs. It has been noticed that here intensity of dis- ease, marked by great febrile excitement, was more likely to develop the contagious element, than the con- dition commonly known as putrescence. Yellow Fever is undoubtedly contagious in degree, sometimes very markedly, and at others so as to exert but little influence. Both conditions of contagion have been noticed : that from great intensity, of disease, with the symptoms heretofore named, and from putres- cency appearing in the last stage with the black vomit. ENDEMIC DISEASES. If disease showing distinct peculiarities is confined to a locality, it is said to be endemic, especially if it prevails to any considerable extent. In such cases the cause is evidently local, and it is evident that many times it may be discovered, removed, or avoided. These diseases have a definite and distinctive expres- sion, which should and may suggest the means of cure. In some the endemic influence is so wholly the cause, and the endemic expression so clearly indicates the STUDY OF DIAGNOSIS. 235 lesion, that remedies will be remarkable for their cura- tive influence. At other times the endemic influence, and disease produced, will be but a part of the wrong, &nd whilst the endemic remedies are important, they are not so certain as before, and have to be aided by other means. The diagnosis of endemic disease is usually very clear : a, There is something distinct and special in the expression of disease ; 6, there are a number of cases, showing these special features ; c, the diseases are re- stricted to definite localities. First among the diseases included in this classifica- tion are all those showing periodicity, including inter- mittent, remittent, and yellow fevers. Following these, wc find that an endemic influence may give rise to the series of continued fevers, to all inflammations, and to many functional and structural diseases. And it is to be noticed that as -a rule the endemic influence intensi- fies the natural disease in addition to giving it special features. Periodicity. — Whatever may be the cause of period- icity in disease, the fact is sufficient^ 7 tangible, easily recognized by the periodic expression, which indicates a special pathological condition, and calls for a special group of remedies, anti-periodics — Quinine. As before remarked, the periodic element may serve as a basis of nearly every named disease, which will be cured by the one remedy, Quinine. Or it may only be a complica- tion, or part of the disease, and Quinine will only be one of the remedies called for. But periodicity does not always mean Quinine, and it is sometimes difficult to determine whether it does or not. All diseases are 236 STUDY OF DIAGNOSIS. periodic to a certain extent, having* periods of increase and diminution, as may be noticed even in the fevers called continued. Indeed all the functions of life, both in health and disease, have something of periodicity in their performance. The diagnosis of periodicity will be made by — a, The marked remission or intermission of the evidence of disease, and return to the healthy standard of life ; fc, the equally marked exacerbation of disease, especially with reference to the wrongs of innervation, tempera- ture and circulation ; c, the disposition to continue such functional aberrations without change of structuve; and d y the fact that such disease is endemic in the localitj r . Intermittent Fever. — We diagnose an ague by — a, the marked cold stage ; Z>, followed by a hot s.tage ; c, a sweating stage — all occupying a comparatively short time, usually less than twenty-four hours ; and f the blood and the tissues. We may sum these up as Iron. Phosphorus, Soda, Lime, Potash, Sulphur, Silica, ^m 274 STUDY OF DIAGNOSIS. Copper, and the bitter principle. These may not be all, but if we can get a clear conception of their use, the wrongs that follow their defect, and the symptoms that point them out, we will do well. As Iron is the coloring material of the blood, want of color is generally regarded as indicating the use of this remedy as a restorative. In some cases the evi- dence is sufficiently clear, and when Iron is given the effect is direct and positive. If taking the symptoms, " want of color from blood, " we are careful in our ex- amination to exclude those cases where other and pri- mary lesions exist, th^ certainty would be almost abso- lute. But there is another indication quite as certain as " want of color," when tissues, especially the tongue, show a solid but not deep blue. In these the action of Iron is specific. Again we find certain lesions of the blood, more noticeably those which give an erythe- matous eruption (erysipelas), in which the redness is dirty or dulled, in which Iron is specific. When the diagnosis is carefully made, the action of Iron will give great satisfaction. A recent case of uterine disease of long standing with greatly impaired nutrition, presented as a prominent feature frequent erythematous eruptions of this dirty, though somewhat vivid redness, and the cervix uteri and vaginal tissues presented the same color. One grain of Iron by Hydrogen three times a day, was sufficient to effect a cure in a month. In another, where there was im- paired nutrition of many years' standing, and no direct symptoms but the solid blue tongue, the patient made a quick and good recovery on Iron alone. The best indication for Phosphorus in its varied forms, will probably be found in the v>an t of expression, STUDY OF DIAGNOSIS. 275. both ill the face and in movement, an enfeebled respi- ration and unequal temperature. The sensations of the patient may point to impaired nutrition of the nerve centres, or simply to a general failure of life. The indications for Phosphorus in the ordinary dose, are invariably of atony — impairment of the circulation and innervation. In a minute dose it may be used where there are evidences of vascular and nervous ex- citement with enfeebled tissue — as instanced in low grades of inflammation of the lungs. Soda "is a true restorative in some conditions of dis- ease. If deficient in quantity every function of life is impaired, and without its restoration recovery can not take place. In some cases want of Soda is the basic lesion, and its administration all that is necessary- for a cure. In others this deficiency is but one of many lesions, and the giving of Soda will be but one of the means employed. The indication for the use of Soda is clear and un- mistakable — want of color in mucous membranes — which are usually full. Usually we are guided by the tongue, and the expression would be full and pallid — Soda. The indications for Lime are not so distinct, but yet quite definite. We are in the habit of saying that Lime is indicated in all idiopathic cases of suppurative disease of cellular tissue. The very fact of inflamma- tion with a low euplastic or cacoplastic deposit, not the result of injury, evidences a peculiar wrong, and for this Lime is the remedy. Furuncular disease in all its forms, finds a remedy in Lime. In the majority of cases, there will be pallor of mucous membranes, though in some cases they will be purplish or blue. Lime is 276 STUDY OF DIAGNOSIS. employed in chronic disease of the lungs, with eaeo- plastic deposit, determined by a low grade of inflamma- tion. The indications for Potash will be found in pallor of mucous membranes, calling for an alkali, and impair- ment of muscular power. In most cases a dull, leaden hue oi mucous membrane with pallor, will point espe- cially to the Salts of Potash. A marked example will be found in syphilis, in which this coloration is the in- dication for Iodide of Potassium. In some cases a Salt of Potash may be needed, even though the deep color- ation calls for an acid ; this is sometimes seen in scurvy. Here the Soda is excess, Potash is defect, and the patient is cured by the administration of Lemon juice and vegetables containing Potash in large quantity. The best indication for Sulphur as a restorative is a change in or want of the pigment of the skin and hair. In some cases the dull, dirty color may call for Sulphur, in others the blanched surface. Rapid loss of color in the hair will sometimes be an indication. Sulphur is also indicated by a peculiar blue or leaden color of urine and faeces. It would be designated by some ? "want of color," and so there is a marked lack of the natural coloring material of these excretions. If I were picking a case to obtain the most marked curative action of this drug, I would take the dirty or tawny skin with bluish urine. The indication for Silica is not very well known. I have used it with most advantage when the epithe- lium had a lifeless appearance, and there was continued tendency to desquamation. In some cases these symp- toms are followed by severe ulceration of the skin. Hahnemann claimed that it was a valuable remedy in STUDY OF DIAGNOSIS. 277 rachitis of children, and named sweating of the head, as one of its most prominent indications. Copper is not usually regarded as a constituent of the body, yet I think it is clearly proven that it is present in small quantity. The indication for its use is the unpleasant greenish pallor of skin met with in some diseases of women, and a veiy similar coloration of tongue. In some cases the patient has not lost flesh, and nutrition seems to be quite as good as usual, but there is a want of energj^ and power of endurance. The Bitter Tonics are in such common use, that it would seem hardly necessary to point out the indica- tions for their use. But one would find it a little diffi- cult to point out clearly the cases in which the bitters are direct remedies. One might say "want of appe- tite," and as by their topical action they are appetizers, he would guess his case off right with the majority. Or we may say "' impaired digestion/' and by their topical action the)^ do improve digestion, and we would be right in the majority. Or we might say " enfeebled nutrition, " and as they do improve nutrition, we would make a right diagnosis in a great many cases. The blood requires a bitter principle, and its want is the cause of most serious disease, yet I can not point the reader to any better evidence of it tban impaired appetite, digestion and nutrition. Further along, we will see that a right circulation is essential to carry the blood, thus well made, to the tis- sues where it is to be used. Wrongs of the circulation impair the quality of the blood, and the power of the tissues to withdraw from it the materials for nutrition. Thus in all cases of lesion of nutrition a right circula- tion must be maintained. In this connection attention 278 STUDY OF DIAGNOSIS. may also be called to the necessity of having the normal temperature of 98°, which, as we have already seen, is a condition of healthy life, A patient may have good food, good digestion, and good blood-making, and yet there will be a failure in nutrition. If the tissues are not in a condition to ap- propriate the material and weave it into organic forms, the patienjb would be better not to take it as food. We have already referred briefly to the properties of form- ative cells, and have seen that we have no means of determining their condition, except by the physical properties of the tissues en masse. If they have normal hardness, elasticity, form, and activity, we have reason to conclude that nutrition is good, in so far as the power of appropriation is concerned. Conversely we may say, if they want hardness, elasticity, form, and activity, there is a want of power to organize new tissue. Diagnosis is here made by the tactile and visual senses, and will be valuable just in proportion as these have been trained to use. Concluding from these evidences that the tissues lack the power of appropriation, what will be the remedies ? In so far as internal remedies are con- cerned, we have but few that influence the function of the formative cells. To a limited extent, some of the bitters may do this. Yet when we subtract their topi- cal influence upon the digestive apparatus in increasing the appetite and improving digestion, and the slight stimulant influence upon the circulation and innerva- tion, there is but a small fraction to be accounted for. Want of hardness, elasticity and activity will show a want of nutrition, whilst the change in form, want of expression — dull and lifeless — may be taken as evi- STUDY OF DIAGNOSIS. 279 dences of a want of retrograde metamorphosis. We have already made reference to the great law of animal life — as an organism is used it gains the power, of re- production and increased use; as it is disused it loses this power. But it is well not to forget that over-use will impair reproduction, the forces of life being thus exhausted. In many cases, after providing for good food, good digestion, and good blood-making, a good circulation, normal temperature, and good innervation, we stimulate the appropriation of material by the tis- sues by well regulated exercise. Or if the patient is over-worked, and thus exhausts his powers of repro duction, by recommending rest. In some cases the patient requires exercise under the influence of the will, innervation in this way being of as much importance as the activity of tissue. In other cases it requires passive movement, with as little expenditure of nervous power as is possible. In some cases the stimulus of electricity becomes an important means, and by its general use normal nutrition of tis- sues may be obtained. The character of deposits may usually be determined by the symptoms indicating the condition of the gen- eral health, and by the local appearance of the part when near the surface. Bearing in mind that good blood will give euplastic deposits, an inferior blood cacoplastic deposits, and a very poor blood aplastic deposits, we will be in a pretty good position to judge. The means of determining this have already been pointed out. As regards the local symptoms we may say that the inflammatory process, regular in its course, is the best evidence of euplastic deposit. All irregularities, 280 STUDY OF DIAGNOSIS. whether of time, intensity, or of the common symptoms — heat, pain, redness or swelling — point to a deposit of lower character. So certain is this that the pl^sieian will very rarely make a mistake if irregularities cause him to employ greater vigilance. If for instance, in local disease, there is too much or too little heat, too much or too little pain, too much or too little swelling, too much or too little redness, or if the color is changed, we are sure the deposit, if there is one, will be low in character. So if the disease runs its course too rapidly, or progresses too slowly, we conclude that the deposit will be of lower grade. So true is this, that we look with suspicion on all alterations of the inflammatory process, and use extreme care in the treatment of such cases. Degeneration is not easily recognized, and in a major- ity of cases it progresses until the destruction is beyond remedy. Of course I exclude granular degenerations of the kidneys (known by albumen in the urine), and degeneration of the liver (known by jaundice), which present characteristic functional disturbance. The gradually decreasing power of continued exertion is an important point in the diagnosis. Persons having de- generation will find themselves incapable of prolonged exertion. There is a want of expression in every part, and the soft tissues sit upon the bones like an ill-fitting suit of clothes. A want of sharpness and strength in the wave of blood as it passes under the finger is an additional element. In the treatment of degenerations we wish to re- establish this " renewal of life." Whilst we want good food, .good digestion and blood-making, adding any agents of the class restorative that may be needed, and STUDY OF DIAGNOSIS. 281 an active condition of the formative cells, we also want increased retrograde metamorphosis to remove the old and degenerated tissue. In so far as the tissue is de- generated it can never be replaced, but it is possible to so improve the function of nutrition, that what yet re- mains may serve the purpose of the organism. The diagnosis of growths belongs to the province of surgery, and requires but a brief notice here. They are classified as benign and malignant, and to deter- mine to which of these two classes a growth belongs is the first object. As a general rule we may say a benign is a growth from the tissues, whilst a malignant is a growth in. A benign growth is distinctly separate from the tissues, and though it may be deeply seated it obtains room for its enlargement by separating them, and occupying the place of the connective tissue. It may interfere with the nutrition and use of tissue by pressure and weight, and in rare cases when inflamma- tory action is set up may form adhesions to them, other- wise it maintains a distinct and separate existence. On the contrary, a malignant growth takes possession of the tissues of the body, and grows in them, trans- ferring the structure into its own lowered forms. It is no respecter of tissue, and occupies one quite as readily as another, taking possession alike of skin, connective cellular tissue, muscle and bones, using the fibrous tissue as its skeleton, and the blood-vessels, lymphatics and nerves, for its supply, waste and innervation. The reader will notice that if in any case it be pos- sible to determine the condition of a growth — from or in — the diagnosis is readily made. A growth that does not interfere with or take possession of tissue, is of necessity benign, whilst a growth that does appropriate 24 282 STUDY OF DIAGNOSIS. the normal tissues is as surely malignant. In a major- ity of cases careful inspection of the part will deter- mine this. A benign growth is generally of uniform consistence, smooth, and of equal elasticity as the hand is passed over it. The reader will readily see why this should be the case, as it has a single point of origin and supply, and consequently a uniform development. But in the case of a malignant growth, its consistence and elasticity will depend to a considerable extent upon the tissues it appropriates, and hence it will be of unequal hardness and elasticity — nodulated. There is a marked difference in the sensations of the part, The benign growth has no nerves, and any sen- sation experienced will be from its pressure or drag- ging upon adjacent parts. The malignant growth appropriates the nerves of the part, and hence inter- stitial pain of a peculiar character is usually found in these cases. A benign growth has no lymphatics, and does not influence the blood other than by withdrawing the materials for its supply. On the contrary, the malig- nant growth appropriates the lymphatics as it does other tissue, and furnishes through them a cancerous lymph which eventual^ produces the constitutional impairment so generally noticed. SECRETION. Among the important functions changed by disease secretion holds a first place, and in the practice of medicine remedies influencing the secretions have held STUDY OF DIAGNOSIS. 283 a first place. But very crude ideas of the function of secretion have been held, and of course the medication based upon these was equally crude and empirical. Whilst phj'siologists have been pretty clear in their teaching that (in the main) secretion was purely a vital function performed through certain cells, called secre- tory, physicians have acted as though they believed it, a purely physical process, like the osmose that occurs through an animal membrane. If secretion is a vital process, life is an essential, and the conditions of life necessary; if it is a physical process of straining, then a dead tissue may secrete as well as a living one. There is little use to talk of diagnosis here, unless we have first a clear idea of the apparatus of, and the conditions for secretion. If we can clearly appreciate that in the case of all the secretions — recrementitious and excrementitious — there must be a membrane con- tinuously giving birth to secreting cells, and that these grow to the normal stature of cells, withdraw from the current of blood the special material of their secre- tion, and then discharge themselves with it in the com- mon duct, we will have a basis for correct diagnosis and therapeutics. Taking one step further, we find that function not only depends upon life, but upon the normal conditions of life. This is true of every part and every function of the bod}'. Studying the life of cells, and secreting cells bear a very close relationship to formative, we find that a certain temperature, circulation and innervation are necessary .* Probably the life of the secreting cell *These conditions are as necessary to the entire organism as to the individual cell, otherwise we would not be benefited by 284 STUDY OF DIAGNOSIS. is not so much affected by changes of these, as the life of the formative cell, but in a certain range it is so de- pendent ; whilst the range is greater the effect bej^ond certain points is just the same. The cause of lesions of secretion maj T be general or local, and the diagnosis is made by an analysis of gen- eral symptoms influencing secretion at large, and symptoms pointing to local lesion of the secreting organs. When secretion in general is affected, we have good reason to think that the lesion is general ; when but a single secretion is affected we have good reason to believe that the lesion is of the organ furnishing the secretion. When all the secretions are involved, the cause, as a rule, will be found in changes of temperature, circula- tion, innervation, digestion, blood-making and waste. knowing them. We haveconstant cognizance of the gross form, while the minute structure is beyond our vision oply as Ve bring the microscope to bear upon it. Let us now see how they are applicable to the body as a whole. - First.—- An original viability is seen to be an imperative condi- tion. A want of this gives us hereditary diseases and early death. A. want of it also gives us an enfeebled life and a want of resisting power to the ordinary causes of disease; while a strong viability gives great resisting power to disease, and long life. This has already had a partial consideration. Second.— A proper supply of nutrient material is also an abso- lute condition, as man only lives by a constant renewal of his bodv. The material for this renewal being furnished, and the cells possessing a normal formative power, life continues in a regular manner. Third. — The circumstances favorible for normal development in man are a normal circulation, innervation, temperature, and excretion. — Principles of Medicine. STUDY OF DIAGNOSIS. 285 If now secretion is to be restored to its normal condi- tion, we want normal temperature, normal circulation, innervation and waste, especially the first three. In a large majority of cases, secretion is re-established so soon as the conditions of life permit, without the use of special means to this end. Thus in acute disease, if means are employed to rectify the wrongs of circula- tion, the temperature and innervation, Ave find that the tendency is to a re establishment of secretion as the conditions of health are approached. Local lesions of the secretory apparatus are best classified as irritative and atonic, as it points out the classes from which our remedies are to be drawn. When a part is involved there will be in nearly all cases such unpleasantness of it as will call the attention of patient and physician to the wrong. It may be pain, or something less pronounced than pain, but it gives the special part a distinctive character sejmrate from the general life. In health the body is a unit, and all sensations are pleasurable, in local disease there is a feeling of separateness between the part and the life, and the severer the disease (as a rule) the more distinct this feeling which regards the suffering part as distinct from the life — a foreign body, which it would be well to get rid of. It is true these subjective sensations are not always pronounced, and in some cases the suffering is so mani- fested that it seems of some other and distant part. Yet if the patient's attention is excited, he readilj^ de- termines the wrong sensation, and our knowledge of nervous distribution and sympathies will soon translate the character and situation of pain. The reader will already have been impressed with 286 STUDY OF DIAGNOSIS. the character of pain as determining the condition of a part as regards excitation and atony. Excluding neuralgia, acute sharp pain is the evidence of undue excitation and an active condition, whilst dull pain and sensations of weight and fullness, indicate atony, with impaired circulation and innervation. It may be said that this method of diagnosis is too gross and arbi- trary, but I think in the majority of cases it will serve as a good basis for the selection of remedies. With this method, we should say the absence of local symptoms points to general disease, and we carefully examine our patient with reference to the conditions of normal secretion. Finding the wrong in tempera- ture, circulation, or innervation, we select from those remedies that influence the particular function, and take that one which in its action is opposed to the dis- ease, and in its influence brings the functional wrong toward the standard of health. Determining a local wrong, we at once think of those remedies that espe- cially influence the organ or part, and take that one which in its action will do that which favors the healthy life of the part. Nothing can be simpler than this in theory, as nothing, I am sure, will furnish a better basis for a successful practice of medicine. Secretion is divided into two classes, recrementitious and excrementitious, and it is well for the reader to have a good knowledge of these distinct from each other, learning the uses of each. We want to know the simple facts, w T ith regard to the use of saliva, gas- tric juice, bile, pancreatic fluid, and the small gland ul® of the intestine in digestion, that we may weigh the wrongs which may arise from changes in these secre- tions. We want to know the value of mucus as a STUDY OF DIAGNOSIS. 287 lubricant and protector of mucous membranes, and of the sebaceous secretions as a lubricant and protector of the skin. And we want to know the value of excre- tion from the lungs, the kidneys, skin, and bowels, as a means of removing worn out and effete material from the body. It is direct thought that we want, for when the mind is directed to a single object it readily grasps it, but when it is made to embrace a multitude of objects, they become indefinite and indistinct. If, for example, we are called to a case of increased secretion of .saliva the diagnosis is easily made, for the senses can not fail to be impressed by the increased amount of fluid in the mouth. But the questions that follow are not so easily answered — is it mercurial? from local disease of the salivary glands? from disease of parts contiguous ? from diseases of the digestive apparatus below ? from disease of the brain ? or from a lesion of the sympathetic system of nerves? It seems difficult at first to make such diagnosis, and yet as the mind considers one after the other of these, with such light as additional symptoms may throw on it, the problem is soon solved, and in its solution we are directed to the particular class from which the remedy is to be selected, and possibty the special remedy which will cure. The example given above is one of the most com- plex, and we will find the others simpler. If we take the secretion of gastric juice we might make a different study. First, is the disease general, local, or sjnnpa- thetic? If the examination is carefully conducted, the absence of evidence of local disease, and of parts with which the stomach is in special sympathy, and the evi- dences of general lesions which might affect the 288 STUDY OF DIAGNOSIS. stomach, will determine the first classification. But if the local symptoms were pronounced, and there was wanting the evidences of general or sympathetic dis- ease we would have determined the second classifica- tion. Whilst if we had pronounced disease of parts with which the stomach sympathizes, as of the uterus or brain, but without marked symptoms of local or general disease, we would have determined the third classification. It may be that we will find two, or pos- sibly three of those causes in some cases, but we reach our conclusions by these methods of examination and thought. If we take the liver as the next example, we will find it necessary to employ a different method. The first questions we ask are with reference to local disease. Has the patient unusual sensations in the right hypo- chondrium, of pain, weight, distension, pressure up- wards on lungs, toward the mesial line on the stomach ? is there tenderness on pressure, sense of fullness when the hand is passed over the part, or can the organ be felt below the margin of the ribs ? Is there expression of disease from adjacent parts, as from the bowels, stomach, lungs? Is there a wrong in the uses for which the bile is secreted? It is always well to get rid of old-time errors, and in these methods of diagnosis we wish to start with a right physiology. What is the use of bile? Your physiologist will tell jou^ possibly, that he does not know, but he is sure that it is not, as was formerly thought, an excretion, but that it is elaborated to serve uses in digestion and blood-making. As you read on, and think of what you are reading, you see the absur- ditjr of the old practice of medicine, which was con- STUDY OF DIAGNOSIS. 289 tinuously looking after the liver and the secretion of bile, and talked glibly of liver complaint, liver disease, "your liver is affected," and about liver pills, chola- gogues, " touching the liver," etc. It requires but little stud}^ to get rid of this old rubbish, and reach the conclusion that the liver does its work very kindly and well, and is an organ that aids nutrition, and not waste. If, therefore, we find a wrong of intestinal digestion, in which the liver is very surely concerned, we may look after the condition of this organ. The secretion is peculiar in color, and sometimes wrongs of the liver may be determined by this. Thus faecal matter is to some extent colored with biliverdin, and if the color is dark we say, excess of bile — if it is light we say deficiency of bile. This method of diag- nosis is a little crude, for there are many sources of error. Thus Lehman showed that the peculiar green stools following the administration of Calomel were not due to any action of that drug upon the liver, but to the presence of Sulphate of Mercury in the faeces. An excess of acid may also produce green stools, as a de- ficiency may render them lighter in color. The cutaneous pigment will prove a better guide than the color of the fasces. The yellowness of jaun- dice will be called to mind as an instance, and many will recollect brownish spots — liver maculae — that are very clearly traceable to the liver and its associate organs. But a change in the pigment less marked than this has a very definite meaning. I allude to a tawny coloration of the skin, giving it a dull, dirty appear- ance. I believe this always points to a wrong of the chylopoietic viscera, especially to innervation from the 25 290 STUDY OF DIAGNOSIS. solar plexus, and indicates the class of remedies that have been regarded as " liver medicines." But the really important point to determine in these cases is, the condition of the organ with regard to ex- cess or defect, in its circulation and innervation — is there excitation or atony? The symptoms are usually distinct so far as this is concerned, and the remedies will be clearty pointed out. And yet there is nothing in which mistakes are so frequently made. Take, for in- stance, a case of jaundice, and the teaching of the books, is to give hepatic stimulants — Podophyllin, Leptandrin, Blue Pill, Calomel, etc., without reference to the condi- tion of the liver. But in one-half the cases, there arc evidences of excitation in pain, tenderness on pressure, and accelerated circulation, increased temperature, dry skin and scanty urine. Surely hepatic stimulants are not remedies here, and they usually do much harm in- stead of good. In such case the patient requires the special sedatives, Gelseminum, Acetate of Potash, the bath, and possibly the cold-pack or fomentations to tho right hypochondrium. In the opposite class of cases, with sensations of weight, fullness, oppression, unequal temperature, etc., such remedies as will stimulate the liver and associate organs will prove remedies. Again we wish to know in this connection that tho bile pigment when once deposited in the cutaneous tissues is never removed by way of the liver, but is always excreted in principal part by the kidneys. In so far then as getting rid of the unpleasant coloration of skin in jaundice is concerned, we might just as well give a remedy to act upon the salivary glands as the liver. There are scores of these olden-time errors in STUDY OF DIAGNOSIS. 291 practice that can only be gotten rid of by a careful study of physiology. The pancreas does a most important work in secretion, one which the physiologist clearly understands, and yet we hear nothing about " pancreatic complaint," " pan- creatic disease," or " touching the pancreas." Indeed there are no pancreatic remedies in our Materia Medica. Why is this ? There is nothing like getting these sub- jects fairly in view, that we may think of them. Leh- man remarks — " The function of the pancreatic fluid in digestion, may be two-fold, according to the above men- tioned properties, namely : to change starch into sugar, and to decompose the fats, so as to render them absorb- able. That it actually performs the former in diges- tion, has been placed beyond doubt by numerous ex- periments. The pancreatic fluid possesses this property in a much higher degree than the saliva; it is opera- tive at even a low temperature ; neither bile, nor gas- tric juice, nor free acids, interfere with the function of the fluid." What then would be symptoms of disease of the pan- creatic secretion? Most surely they would be func- tional, and we would find them in imperfect digestion of calorifacient foods, a deficient supply of burning material, and a more or less rapid consumption of the fat stowed in the body. We would naturally expect to find unchanged starch and fat globules in the fasces, and examination shows that this is the case. Just so soon as we begin to reason rightly, we reach definite results. But if we have no " pancreatic medicines," how will we rectify these wrongs, after we have found them ? This is also easy enough. There are in almost all cases 292 STUDY OF DIAGNOSIS. certain general lesions of the circulation, temperature, innervation, excretion, etc., easily recognized, and which must be relieved in all cases preparatory to a successful local treatment. As local remedies we may think of Veratrum, Cactus, Chelidonium, Oxide of Zinc, Nux Vomica, Podophyllum, Iodine in minute closes, Panax, etc. They all act " there or thereabouts," and we can choose from the list those that act in the right direction. To the doctor in ordinary, the intestinal canal is a place to put pills, powders and potions, for purgation. Bowels were made to be moved, and it is the doctor's business to move them, and sometimes, it seems, it is almost his whole business. He never thinks that the intestinal canal is a digestive .apparatus, and if he has ever learned this in his physiology he has forgotten it. And yet this function of the intestinal canal is really the most important element in digestion. In addition to the bile and pancreatic fluid, we have an intestinal fluid secreted by the " bottle- shaped " glands of the alimentary canal. With regard to this Lehman remarks — u The intestinal fluid serves, as re- gards its function, as a complement to the digestive fluids, the gastric and pancreatic fluids, which become inoperative toward the middle of the small intestine ; it possesses not only, as the latter of these does, the power of rapidly changing starch into grape sugar, but also of dissolving and rendering absorbable flesh and other protein bodies. In tied knuckles of intes- tine, into which starch or paste has been introduced, all the starch is transformed into sugar at the end of three hours, and in a great measure absorbed. Pieces of meat or coagulated albumen disappear from such knuckles after six to fourteen hours." STUDY OF DIAGNOSIS. 293 This is good reading, my friend of many cathartics, and it is well to give it a prayerful consideration. Here is a fluid that will do the entire work of digestion, and here is an apparatus that really does do a considerable part of it. When you have occasion to use the old- fashioned harsh remedies, think twice, and possibly you may see that the wrong done to this important function may outweigh, man}' times, the good that comes from counter-irritation. The remedies named above, for wrongs of the pan- creatic secretion, may be employed here, with some additional ones. What we want to know, as a basis for a rational prescription is — do we want sedation or stimulation — do we want it of the circulation, or the innervation, though these are usually associated. It is hardly worth while to point out now the special indi- cations for Amygdalus, Bismuth, Nux, Chelidonium Aconite, Ipecac, Nitric Acid, Podopl^llin, etc., for their uses will have been learned elsewhere. Mucus is secreted to lubricate and protect mucous surfaces, and in normal amount it favors the perform- ance of function. Wrongs of the secretion are usually easily determined. If of the outlets of the body, the condition may be seen and felt. Thus it is easy to re- cognize increased secretion from the nose, throat, and genito-urinary passages, from the abundant discharge. Increased secretion from the bronchial mucous mem- branes is known by its discharge, and also by the blow- ing and rattling sounds heard during cough and on auscultation. Increased secretion of mucus in the stomach is usually shown by the heavily loaded tongue at its base. Whilst increased secretion of mucus in the intestinal canal will be shown by .the uniformly dirty 294 STUDY OF DIAGNOSIS. tongue, and by the tumid abdomen. Scanty secretion gives rise to irritation, and this is one of the prominent signs, and taken together with the absence of discharge is very good evidence. With a wrong of mucous secretion we ask the ques- tions — what are the general wrongs, operative in this case ? what is the condition of the mucous membrane, as regards its circulation and innervation? It is a rule in practice, to rectify any general lesions, prepara- tory to the cure of local disease, and many times with this the local disease will disappear. Thus in a given case of acute disease, we have a frequent pulse, high temperature, and excited innervation, with dry mucous membranes; the use of the appropriate general reme- dies will establish secretion. And on the contrary, if secretion is too free, the use of appropriate general remedies will lessen it. When we think of local remedies we want to grouj), a, those which act upon mucous membranes ; 6, those that act upon the special organ, part, or function in- volved. Having the classes of remedies before us, we now select a stimulant, sedative, or one which by its action tends to change the character of the secretion or function. It is not difficult to select a local remedy if we know exactly what needs be done, and we have a clear knowledge of the value of remedies. A change in the sebaceous secretion frequently gives rise to cutaneous disease. If our attention is directed to the function of this secretion, as a lubricant of the skin, its lesions will readily be detected. The treat- ment here will have reference to the condition of exci- tation or atony of the circulation and innervation, and to changes in the nutrition of the organ. Sedatives in STUDY OF DIAGNOSIS. 295 the one case, stimulants and tonics in another, and remedies that alter morbid action in others, will be selected to meet the different cases. A wrong in the secretion of tears, or the meibomian secretion, may occasion serious trouble with the eye. Profuse lachrymal secretion is sometimes a source of irritation, always a source of feebleness to the tissues. Scant}- secretion on the contrary, by leaving the eye dry, and without the protection given by this fluid, is a cause of irritation. The secretion of the meibomian glands serve an important purpose, and when in excess or defect, the function of the eye is impaired, and un- pleasant disease may be grown. Just so soon as the mind is directed to the parts which may be diseased, it is pretty certain by direct symptoms or by exclusion, to determine the exact loca- tion and kind of disease. Then knowing the action of remedies, local and general, these may be selected with reasonable certainty. A wrong in the secretion of cerumen is a vciy fre- quent cause of partial deafness, and many aural un- pleasantnesses. It is surely well to know this, and by a careful examination determine the character of the disease — whether in excess, defect or perversion — and also the condition of the secreting structures as it re- gards increased excitation or atony. With such knowl- edge as may be readily obtained by any one, the treat- ment of these diseases becomes successful. The principal object in the consideration of these secretions is to call attention to the necessity of con- stantly keeping our physiological knowledge well in hand, and directing attention first to the use, that we may be able to understand the disease. If at any 296 STUDY OF DIAGNOSIS. time we forget this, and tako the ordinary writers on pathology and therapeutics as authority, we are quite sure to go astray. The excrement it ions secretions are four in number — the lungs, the skin, the kidneys and the bowels — and these remove the waste of the body. The due performance of the function of excretion is essential to health, and in disease we invariably find a lesion of one or more. If the excretions are in excess, debility is the result, and becomes a prominent symptom. If they are in defect, materials which should be removed, are re- tained within the body; the result being irritation or oppression, according to the character of the material, and the amount retained. Excretion by the lungs is but little studied, and yet this is one of the most important of the excretions, being to the extent of 517 grains of carbonic acid per hour. In a rough estimate the value of these excretions may be written — lungs eight, kidneys two, skin and bowels each one. True it is carbon which is thus ex- creted by the lungs, (this being regarded in the olden- time as the special province of the liver), but a simple experiment in closing the mouth and nose of an animal will show that it will kill in a very few moments. Excretion by the lungs may be in excess, and this will be seen by the vivid redness of the blood where it reaches the surface, by the frequent full respirations, an exalted circulation, an excited nervous system, a high range of temperature, and rapid waste of tissues. We find these evidences of excess both in acute and chronic disease, and it must be evident to the reader, that means to check it will be of value in both cases. Such a remedy as Veratrum, and to a less extent STUDY OF DIAGNOSIS. 297 Lycopus, Cactus, Sticta, must prove of great value in such cases, associated with such local and topical ap- plications as relieve irritation and give rest. The reader will see very clearly that in the early stage of pneumonia with such symptoms, Veratrum and a mush- jacket may prove speedil}' curative, and that in some cases of phthisis, Veratrum becomes a prominent remedy. Defect in excretion from the lungs will be known by the darker color of the blood where it conies to the surface, the evident defect in the movements of the chest, fullness of superficial veins, and the oppression of all the functions from retention of carbonic acid gas. At once our attention is directed to such remedies as prove excitant to this function, as Xux, if there is de- ficient spinal innervation, Phosphorus, Arsenic, Lobelia, Bryonia, Drosera, Apocynum, etc. If by these means, excretion of carbonic acid can be increased, the various functions of life are relieved from oppression. Even if this knowledge did not point us to special remedies, it would be valuable as suggesting a proper hygiene, The patient suffering from excess wants quiet and rest, a moist atmosphere, and one not stimu- lant. The patient suffering from defect requires such exertion as will call into action the respiratory appa- ratus, a dry atmosphere, and one which is stimulating. Proper direction in these regards may be the one thing necessary to recovery, and we can only give such ad- vice when we thoroughly understand our case. The attention of physicians has been specially directed to the skin, kidneys and the bowels, as the apparatus of excretion, the importance of this function to health, and as a cause of disease. Indeed they have 298 STUDY OF DIAGNOSIS. received too much attention (such as it was) for three- fourths of the Materia Medica has for its object an ac- tion on these emunctories. If we should take away from the regular physician his cathartics, diaphoretics and diuretics, he would be poor (for harm) indeed. Whilst I do not wish to depreciate these functions, either in health or disease, I think a much more care- ful study should be made of them, and that their thera- peutics should be improved. This fact should be especially learned — that in a large majority of cases wrongs of excretion are depen- dent upon changes in general conditions of life — the circulation, temperature and innervation — and that when these are corrected, the excretions resume their normal condition. Even when the function is not re- stored, very simple means are usually all that is required. Excess in secretion from the skin is readily deter- mined by its moisture to the touch, dampness of the clothing, as well as by the patient's sensations. The questions that follow are — is it from excitation, or is it a result of debility? It rarely results from excitation in disease, though once in a while from increased circu- lation to the skin, as in some cases of rheumatism, and in the so-called sweating fever, and some other anoma- lous cases, this will be found to be the case. Here the diagnosis is quite clear — the skin has an active circula- tion, is deepened in color, and the temperature is in- creased. The increased perspiration of debility is not secretion, but an exudation of water, washing away a small quantity of albuminoid materials. The condi- tion is determined by the evident relaxation and loss of tone to the touch, the pallor, and usually the want of sensitiveness. STUDY OF DIAGNOSIS. 299 Evidently the treatment will be different in the two cases. The one of excitation requires the special seda- tives, Aconite, Veratrum. Gelseminum, or special reme- dies influencing the sympathetic nervous system as the Rhus, Ly cop us, etc. We want to relieve the undue ex- citation of the skin, and this accomplished the sweating ceases. In the other case an opposite treatment is re- quired. Here we select such remedies as stimulate the the skin — stimulant diaphoretics — Serpen taria, Senega, Erigeron, Erecthites, Polygonum, etc. Or stimulants to the circulation and innervation, as Belladonna, Lobelia, Ipecac, Bryonia, etc. Local means will vary just as much, in the one case being sedative, in the other stimulant. Defect in secretion may usually be known by exam- ining the skin, which in one class of cases gives the hand a sense of dryness and constriction, and in another dryness with want of elasticity and life. The symp- toms produced by retention of this excretion, are first of oppression, terminating in chill, and second of exci- tation, giving the phenomena of fever. As will be seen, the general symptoms are somewhat indefinite, for both the oppression and stimulation may be the result of other causes. It is well to give due weight to this lesion, though we ma} 7 not rest our entire practice upon it. If the defect in secretion is due to an increased cir- culation and temperature, means to rectify these wrongs will stand first. In a majority of cases of fever and in- flammation, a right use of the special sedatives and proper baths will place the skin in such condition that it will resume its function ; or that it can be called into action by very simple remedies. In other cases, where 300 STUDY OF DIAGNOSIS. the wrong of circulation, temperature and innervation is bused upon other special lesions, the use of the special remedy for this, is followed by a return of normal cir- culation, temperature and secretion. A marked ex- ample of this will have been seen in the administration of Tincture of Muriate of Iron in some cases of erysip- elas, as well as in the use of Ehus, when special!}^ indicated. If the defect is due to a want of excitation in the cutaneous nerves and circulation, remedies are employed which exert a stimulant influence upon the skin. Many diaphoretics owe their power to influence this secretion to their stimulant influence, and of course they can be beneficial only when a correct diagnosis is made, and they are rightly used. Perversions of this secretion are not uncommon, but owing to our imperfect means of diagnosis are rarely recognized. " This fluid, (sweat), as it collects in drops on the skin of one perspiring, is colorless, tastes salty, has a peculiar odor, is poor in solid constituents, and, when recent, always reddens litmus." Yet we find in disease that it has color, sometimes to the extent of coloring the clothing, varying in shade and intensity ; has a variety of tastes, sweet, sour, acrid ; is rich in albuminoid elements ; and is sometimes neutral to test paper, and in other cases will change red litmus blue. Evidently here is a field that will repay investigation. Authorities upon skin diseases have recognized the fact, that perversion of the secretion may be a cause of some of these, and may perpetuate the most intract- able. In so far as we know now treatment will be directed to the physical condition of this organ, as shown by STUDY OF DIAGNOSIS. 301 examination, and to lesions of the blood. The last are sometimes very important, for so long as there is in this fluid morbid material that is excreted by the skin, so long will the skin suffer. Before leaving this subject, I wish to call the reader's attention to the character of normal cutaneous secre- tion, and to the fact, that in so far as it is a secretion it is effected by secreting cells. In its normal state the skin has a uniform temperature slightly below that of the blood, gives to the hand a pleasant sensation of softness and elasticity, is not damp and moist, indeed rarely shows moisture upon the surface except on in- crease of temperature and exertion. As this is the condition in which it does the best work, it is the con- dition we wish to obtain in disease. Many act as if they supposed secretion from the skin necessitated the pouring out of an increased quantity of fluids upon the surface, as from the old class of sudorifics. Yet in practice we find that the soft and but slightly moist skin is the best evidence of secretion. We have already studied the urine as an index to disease and a means of diagnosis, and it will only be necessary here to notice a few of the more salient fea- tures connected with this study. Whilst the physician is aware that the seeretion of urine is indispensable to life, in that it removes the largest portion of the nitro- genized waste, he finds the common means of diag- nosis so defective, that he takes it for granted that the kidneys are doing their work right, because in a very large percentage of cases, they do their work right. As a matter of form he will ask — "how is your urine? " and in the olden time he might examine a mixture of urine and faeces in the chamber utensil. If the patient 302 STUDY OF DIAGNOSIS. complained of scanty urine, it might mean something, if there was uneasiness in voiding it, there was prob- ably something wrong, and if there was arrest, very surely something must be done. But just what that something should be, was not so definite, only that it must be drawn from the class diuretics, and was usually the favorite prescription. In this study it would be well for us first, to see wliy in any case the urine should receive a special examina- tion, and then how this examination should be con- ducted. We take it for granted that in ordinary prac- tice examinations of urine will not be made. In acute disease retention of the elements of tho urine are so clearly shown by the nervous system, that there can hardly be a failure to have our attention directed to them. The first influence is that of excita- tion — the patient becomes restless and irritable and suf- fers more than the condition of disease will account for. The second influence is of oppression — the patient be- comes dull and lethargic, and finally sinks into coma. Of course Ave may have cerebral excitation and coma, without any wrong of the urinary secretion, but we never fail in these cases to make diligent inquiry, and satisfy ourselves as to the source of the nervous lesions. Now scanty urine has a definite meaning, as has un- pleasant sensations in its passage, or a failure to pass it, or going further, we may make a critical examina- tion of it, as heretofore named. I do not wish to be understood as saying that inquiries with regard to tho urine need not be made unless there is nervous dis- turbance, for there can be no harm in thorough exami- nations in all directions — but I desire to impress it STUDY OF DIAGNOSIS. 303 upon the mind of the reader that these are the cases where such examination is imperative. But finding a failure upon the part of the kidneys to do their work, we are not yet ready to say — give " diu- retics*" We want to know the condition of the kid- neys as regards their circulation and innervation. Such arrest may result from irritation and determination of blood, and any excitant may so increase this as to en- tirely suppress the secretion and cause death. Or it may result from capillary congestion, which the ordi- naiy diuretics would increase, and thus death might result from the use of remedies which in ordinary cases would increase secretion. The condition of the kidneys may be determined in part from the patient's sensations, and in part from a personal examination. In irritation with determina- tion of blood (active condition) the patient will have a sense of constriction in the loins with tensive or draw- ing pain, sometimes seeming to be in the spine. Some- times the sense of irritation extends to the bladder, the urethra, the testes, and even to the rectum. In irrita- tion the patient is restless, quick in his movements, the eyes are bright, the tissues around them seemingly con- tracted, the tongue small and pointed, and the pulse small, wiry, or vibratile. In congestion the patient complains of a sense of fullness and weight in the loins, and sometimes the same sense of fullness and weight in the pelvis. The patient is dull and apathetic, the eye dull, the face expressionless, the tongue somewhat full, and the pnlse lacks sharpness in the wave — op- pressed. Such diagnosis is of especial value, because it en- ables the practitioner to select his remedies with cer- 304 STUDY OF DIAGNOSIS. tainty. If we have the condition of irritation, we give Gelseminum, with or without the sedatives, as may be indicated. If there is the condition of congestion wc give Belladonna, Ergot, or Solan um, with or without Aconite as the sedative. Diuretics are not given until there is marked relief, and secretion has become more free; indeed, sometimes they will not be required at all. When we do give them, they are selected with refer- ence to the condition of the kidneys — sedative diure- tics for the condition of irritation, stimulant diuretics for that of congestion. Excess in this secretion is not of frequent occurrence, and is usually recognized without trouble. The large amount of urine in diabetes, insipidus and mellitus, at- tracts the patient's attention, and is evidence to the physician of the nature of the wrong. But there are a few other cases in which the excess is not marked in this way — the patient passing but the usual amount of urine, or possibly it is less in volume than usual. It is only when tested with the urinometer that it is found continuously of high specific gravity, and that the solids are increased from one-tenth to possibly one- fourth more, and still it does not contain sugar or albu- men. Such excess will be marked by loss of flesh and strength, and by feelings of weight and dragging in loins or pelvis. The wrong may be wholly due to a lesion of the kidneys, or principally to an excess in retrograde me- tamorphosis. This of course must be determined to give us a rational treatment. Attention is rarely called to lesions of perversion by the common examinations of the urine. Of course there are exceptional cases, as the excess of urine in STUDY OF DIAGNOSIS. 305 diabetus nielli tus, and urinary irritation in some cases of deposit, in which the direct symptoms are sufficient to excite attention. In the majority, the diagnosis is made by exclusion. There is an impairment of the health; object — to locate and determine the character of the lesion. And thus we give the patient a thor- ough examination, with reference to the more import- ant functions and organs. Is it of the circulation, digestion, respiration, innervation, nutrition, secretion of skin, bowels, kidneys f Thus excluding one after the other, as we find them free from disease, we at last reach the affected part. Even now we do not know the character of the lesion, and proceed by the same method to determine it Is there sugar in the urine, albumen, blood, the phosphates, or some of the rarer morbid materials? The general symj)toms may point us to the special examination, or we may be obliged to make test after test, until we determine what the real trouble is. But having learned the character of the perversion, we are not yet ready for treatment. It will not do to say, here is a remedy for all cases of diabetus mellitus, albumien blood, deposit of the triple phosphates. The examination must go a step further — to what extent is it a lesion of the kidneys, or of some other part, the blood, nervous system, or the associate secretions from lungs, skin and bowels? and still a step further, we want to know the physical condition of the kidneys, and the special character of any other wrong. The reader may say these methods are very com- plex, and it will be difficult for one to follow them out (?) I admit it, and whenever possible, should rather prescribe from a single characteristic symptom, but 26 306 STUDY OF DIAGNOSIS. there are cases that require just such thorough analysis to give succeesful treatment. When we study excretion from the bowels, we want first to correct our physiological ideas of the value of the secretion. Plrysicians have made a hobby of the bowels and have ridden millions of them to untimely graves. We want to know if bowels were made to be continuously phj^sicked? and whether good or harm is most likely to result from the common use of purga- tives ? If we consult Lehman again, (a most excellent authority), we find that — "The contents of the intes- tines, even after the use of tolerably simple articles of diet, consist of a mixture of undigested, indigestible, and already changed or decomposed substances, with which are mingled constituents, partly undecomposed, partly already metamorphosed, of the digestive fluids." But of a real secretion eliminated by the glandulse of the intestine the faeces contain but a small proportion — probably less than the excretion from the skin. Excess is usually associated with frequent fluid evac- uations — diarrhoea — yet we must not take it for granted that in all cases of diarrhoea there is excess. Excessive discharges of fasces produce debility, first by the re- moval of some portions of the food, and secondly by withdrawing some of the albuminoid materials of the blood. Constipation is not to be regarded as positive evi- dence of defect in secretion from the bowels, as it is possible, and not uncommon, for constipation to exist for days, and yet excretion goes on into the bowels as before. But even constipation may be a cause of dis- ease, either from irritation produced by the debris of digestion, or by the decomposition of some of the STUDY OF DIAGNOSIS. 307 material, or by the generation of offensive gases, or the absorption of some of the decomposed matters. Evi- dences of irritation, or of oppression, when they can be referred directly to inaction of the bowels, may be regarded as an indication for the simpler cathartics. The more harsh remedies of this class have usually been used for their derivative effect, and the saline hydragogue cathartics to deplete the blood-vessels of fluid. Small doses of some of the cathartics, as Podophyl- lum, Apocynum, etc., do increase the secernent function of the intestine, and at the same time improve its func- tion of digestion. The dose is less than that required for catharsis, and the indications are sensations of full- ness, weight and atony. Perversions of the secretions of the bowels and acces- sory glands are recognized principally by changes in color and in odor, but these are not as certain as would be thought at first sight. The reasons are clear — there is so much and varied coloring material taken with the ingesta, and the odor naturally intense and foul is so readily changed by decomposition of faecal material. Still it is well to make the faeces yield all the informa- tion possible. A few examples may be given in illustration. The vivid green discharges of childhood, acrid and irritat- ing, give information of excess of acid, and suggest the use of alkalies. The extreme yellow (chrome) of in- fantile discharges, evidence an insufficient digestion of the food, both of albuminoid material and fat, and sug- gest more care in diet, and the use of remedies that give tone to the digestive apparatus. The clay-colored evac- uations of disease tell of want of secretion from all 308 STUDY OF DIAGNOSIS the intestinal glands (liver included), of impaired power of digestion, and suggest the use of stimulants to- the upper intestinal canal and associate viscera. The yellow rye-mush feces of typhoid fever is characteristic, and calls our attention to commencing disease of Peyer's glands. The deep brown or black feces, with greenish tinge, sometimes yeasty, is one of the most marked in- dications of the typhoid condition, and calls attention to the necessity of antiseptics. The color and physical properties of mucus, pus and blood, are readily \*ecog- nized, and either by their quantity, condition, or some local symptoms, their source may be readily detected. THE BLOOD. The study of the blood is one of much interest to the physician, for in changes of its structure and circu- lation Ave find a principal element in many diseases. The old Hebrew poet well remarked that — " the blood is the life of the man," at least Ave find by experience that Avrongs of the blood are manifested by impairment of the life. We study both the lesions of the blood and the lesions of its circulation, and it is well to keep them separate in the mind. Excess in the amount of blood is of very rare occur- rence as a cause of disease, and yet occasionally Ave meet with cases in which, from local disease, the high stimulus of a large amount of rich blood is injurious. We find such cases in local disease of the kidneys, the lungs, the heart, the brain, in which these organs, en- feebled by disease, can not bear the strain of such vig- orous life. This has been named sthenic plethora. STUDY OF DIAGNOSIS. 309 There is another condition in which a large amount of blood is continuously made, but owing to exhaustion of the circulatory apparatus and nervous S3^stem by ex- cesses, its circulation is sluggish. Excess of blood is readily recognized by the fullness of the blood vessels, especially of the capillary system of the surface, which shows the deep tint of abundant red globules, by the full firm tissues, and the vigorous performance of function. Asthenic plethora will be recognized by fullness of blood vessels, oppression in the stroke of the pulse, and a turgid venous circulation, giving the surface the peculiar color of venous blood. The color is so characteristic, that when associated with the full animalized tissues, and the full blood vessels, there can be no mistake in the diagnosis. When high stimulus is likely to be a source of danger, we take measures to lessen the quantity of the blood. The safest means is to diminish the supply of food to a minimum, and select such vegetables and fruits as yield small proportions of nitrogen ized material. In some crises the saline purgatives and diuretics may be em- ployed to a limited extent with advantage, which, with well regulated exercise, will remove the source of danger. Many a man has lost his life because his digestive and blood-making organs were so much better than the remainder of his body, that they have furnished the material for a too active life. In asthenic plethora the important remedy is right living. Cut off the supply of stimulant drinks and food, establish good excretion, and have the patient take such exercise as will promote a more rapid combustion and waste of effete material, and in a few months the patient will be on safe ground. 310 STUDY OF DIAGNOSIS. Defect in the quantity of the blood — ancemia — is readily recognized by the want of color of surface, and the loss of that hardness and elasticity of tissue that we call tone, and a loss of size and functional activity of the soft structures of the body. " As the life of the man is his blood," we have a loss of life in proportion to the condition of anaemia. But we may have gone so far in our diagnosis as to determine absolutely that there is a want of blood, and yet not be ready to make a prescription. It will not do to say, give Iron, or give " Bitter Tonics and Iron." We want to know why a sufficient amount of blood is not made, or why, if made, it is not applied to its proper use — nutrition. In one case it will be a want of proper food, or of some special element of the blood, in another a want of buccal, gastric or intestinal digestion, in another a wrong in the blood-making organs, in an- other a lesion of the circulation, in another a lesion of innervation, in another a lesion of retrograde meta- morphosis or excretion. Is it too much to ask that each of these receive due consideration, and that our prescription should be directed to the special fault? It requires a little time to pass all this in review, but the mind works very rapidly, and taught to work right, it will do all of this automatically. Of course the treatment of anaemia must vary in different cases, as the cause of it varies so much. In one case good food, well prepared, is all sufficient ; in another some special element of blood needs to be added — as Iron, Phosphorus, Soda, Potash, etc. ; in an- other the digestive apparatus requires stimulation ; in another special stimulants are required -to increase sym- pathetic innervation ; in another special means to give STUDY OF DIAGNOSIS. 311 a right circulation and temperature ; in another stimu- lants to the formative cells by remedies and exercise ; and in others still the cure comes from stimulating the processes of waste and excretion, thus getting rid of old and feeble forms. The consideration of spanhcemia, or poor blood, is hardly necessary here, because it is included in the general term anaemia. Whilst it is possible to have a normal amount of blood, yet poor in some of its ele- ments, this is a rather rare condition. It will be known by the full, limp, inactive tissues, the full, blue veins, the full pulse without power in its stroke, and the ten- dency to dropsical effusions. It is really a worse con- dition than a simple anaemia, and requires more care in its treatment. As we employ means to increase the formation of blood, and add those elements necessary to its proper structure, we at the same time wish to get rid of the old stock, and the safest way to do this is by well regulated exercise and gentle stimulation of the apparatus of excretion. As remarked under the head of anaemia, special con- sideration is always given to a want of some of the ele- ments of blood, and to the means which will restore them. This is the basis of the treatment called restora- tive. If the blood requires Phosphorus, it will not do to give it Iron, as when it requires Iron it will not do to give it Sulphur or a bitter. The special symptoms heretofore named, showing these defects, should be closely studied. But the blood may be bad, or changes may be going on within it which will work its destruction. You may say that " bad blood " is a popular myth, and does well enough to base a nostrum advertisement upon, but 312 STUDY OF DIAGNOSIS. it will hardly do for specific medication (?) There you are wrong, for " bad blood " is a real, tangible entity, with definite expressions, and a definite therapeutics. How will we recognize it? Assuredly in the ordinary way, by an inspection of it where it sIioavs at the sur- face, by any material (secretion) that is drawn -from it, and by wrongs in the nutritive function which is based upon it. When you think of these methods for a moment you will see that they have a physiological basis, are plain, and eminently practical. In acute disease we are more interested in those changes going on in the blood which we call septic, than in any special material contained within it, and these changes are more readily recognized by exuda- tions than other means. Attention has already been called to the secretions and deposits upon the tongue, as evidencing the condition of the blood. We find that all exudations that might be called dirty, and all changes in color toward brown and black, might be regarded as certain evidence of sepsis, and of the impairment of the blood. We put the proposition in this form — "as are the secretions of the mouth (notablj 7, the coating of the tongue) dirty or of deep color, so is the intensity of sepsis, and the death of the blood." In so far as the term typhoid is applicable to sepsis, these symptoms are among the most prominent in typhoid diseases. Any exudation will serve to show the character of the blood as well as the coating upon the tongue. The discharges from the bowels and of urine, the sputa in disease of the respiratory apparatus, the lochia in puer- peral disease, the " washings-of-meat" discharges in dysentery, the secretions of an ulcer, the sanies of an injury or surgical operation, all tell the story explicitly. STUDY OF DIAGNOSIS. 313 It is not possible to get a good secretion or exudation from septic blood, and the character of the one will show the condition of the other In some forms of chronic disease there is effete or imperfectly elaborated albuminoid material in the blood in considerable quantity. It serves to lower the char- acter of this fluid, and to impair all vital activities, and by influencing the nutrition of structures it gives rise to local disease. This bad blood has been a basis for the administration of the various compounds called alte- rative, so extensively employed by the profession, and also for nostrum venders, and no doubt the treatment adopted, by increasing waste and nutrition, has cured many cases. The evidence of bad blood is best found in wrongs of excretion and of nutrition. There can not be a wrong of this character without an effort upon the part of the skin, kidneys and bowels to remove the unpleasant material, and we will usually find that all three of these emunctories show a lesion caused by the effort, though one ma} r suffer more than another. In the case of the skin it manifests itself in cutaneous disease, taking the forms of the exanthemata in the simpler cases, and the graver forms of the pustulse, squamae and tuberculae, when the lesion is more persistent and severe. This fact has long been recognized, in so far as the treat- ment of skin diseases has embraced means for remov- ing effete and unpleasant materials from the blood. We frequently hear it remarked, "I know my blood is bad, because my flesh does not heal easily, and wounds and scratches inflame and suppurate." True there is something wrong here, and it maybe " bad blood," according to our definition above. At least in 27 314 STUDY OF DIAGNOSIS. a large number of cases, a treatment that looks to the increase of excretion, and better digestion and blood- making, removes all the unpleasantness. In the re- maining cases some special material of the blood is wanting, frequently Lime, sometimes Soda, Potash, Phosphorus, etc. In some cases the urinary apparatus is the special seat of suffering. The entire apparatus is irritable, and the urine contains an abundance of ammoniacal com- pounds, and gives characteristic deposits. The effort at removal may be continued by these organs, until severe disease is induced, as seen in some cases of chronic in- flammation, and an occasional case of degeneration. The bowels always suffer more or less, indeed 1 hardly think it possible that this condition should continue long, without a loss of regularity in defecation, and a change in the character of the stools. The lesions of nutrition may take the form of de- generation, or of deposits. In the one case we have the symptoms heretofore described, of enfeebled func- tion, and a want of expression in the soft tissues. In the other comes the evidence of local disease, enlarge- ment preceding inflammatory action, which, runs a very irregular course. The last is so important an evidence that it is well to read it over. Whenever swelling and change in the form and functions of a part precede inflammatory action, there is a wrong of the blood, and means must be employed to remove the unpleasant material by excretion, and to provide for better blood- making. In place of thinking of certain remedies called " alte- rative," which act in " an insensible and inexplicable manner," it is best to think of the process of cure. STUDY OF DIAGNOSIS. 315 The bad material is to be removed, and good material is to be introduced in its place. We wish to know whether it is necessary to employ means to stimulate retrograde metamorphosis, by exercise or medicines, to increase the processes of combustion, to employ remedies that modify and arrest the septic processes, or to use such as increase excretion It is possible that the habits and surroundings of the patient must be changed before a cure is effected, or that he should have better food, better digestion, or better blood- making. In thus getting a better blood, there is less tendency to depravation. THE CIECULATION OF THE BLOOD. Among the most common lesions in disease are wrongs of the circulation of the blood. We may state it as an axiom that the condition of health requires a circulation normal in time and character, and just in proportion as we have a change from this normal standard we have severity of disease. The time of the pulse varies greatly in different individuals in a state of health, in the adult having a range of from 50 to 90 beats per minute, yet in its other characteristics it is pretty uniform, and can hardly be mistaken. The finger on the pulse is trained to determine lesions of the circulation, and should rarely make any mistake. The wrongs of the circulation may be general or local, and classified under the three heads, excess, de- fect and perversion. The first has reference to rapidity, the second to an impairment or checking of the circu- lation, and the third may embrace cases in which the circulation is not uniform, or is irregular. 316 STUDY OF DIAGNOSIS. Increased frequency of pulse is one of the character- istic symptoms of fever, and is usually associated with a proportionate increase of temperature. As a rule we estimate that ten pulsations represent 1° of tempera- ture — that is for each degree of increased temperature we may expect to find an increase often pulsations per minute. There are many exceptions to this rule, the increased frequency of pulse being sometimes more, sometimes less, and indeed sometimes showing but little relation. As a rule, increased frequency of pulse represents gravity of disease, and we are accustomed to think of it as an unpleasant symptom. As is the frequency of the pulse, so is the arrest of secretion, the increase of heat, the impairment of digestion and blood- making, the arrest of nutrition, the development and progress of sepsis, the progress of inflammatory dis- ease, and the danger to life, local and general. Hence the importance of means which influence the circula- tion, reducing its frequency without impairing its free- dom. Frequency of Pulse may be the basis of fever or inflammation, and when the pulse is brought down to a normal standard all the other phenomena of disease may disappear. Thus we often observe under the in- fluence of the special sedatives, that as the frequency of pulse is reduced, the temperature falls, the nervous system is relieved, the skin softens and becomes moist, the urine is increased, the bowels move of themselves, and the appetite returns. Or, in case of inflammation, the pain, ceases, there is less heat, redness and swelling, and resolution rapidly progresses to complete restora- tion. These results are so common, that we are sur- prised in some seasons and in some cases to find that the sedatives do not seem to produce sedation. STUDY OF DIAGNOSIS. 317 This brings up the important point in the study of disease — that there is a first and predominant wrong upon which the entire morbid process rests. In some cases, as in the instances given, this is so markedly the case that when Ave have removed this, the whole disease rapidly fades away. But in others this simply paves the way for the doing of something else, and this again for the restoration of other functions, and thus a suc- cession of means may be required in a single case. It will not do to say here, I have frequency of pulse, and my patient requires a sedative, taking any one of this class at random. The ten or a dozen remedies grouped under this head are not alike, and can not be used one for the other. It is true that we may so sub- stitute Yeratrum and Aconite in many cases, but even these had better be given according to the special indi- cations heretofore named — Yeratrum when the pulse is full, Aconite when it is small. Then we have Digitalis when the impulse is feeble, Lobelia when it is op- pressed and the artery is turgid with blood, Gelsemi- num when it is full and vibratiie, Belladonna when it is full, soft, and without strength, etc. For these indica- tions and others, the reader is referred to a former con- sideration of the pulse as an element of diagnosis. Slowness of Pulse is not a common symptom in disease, but is occasionally met with in chronic disease. It indicates a want of innervation, or excitability of parts supplied from the sympathetic. The wrong may be found in degeneration of tissue, or simply a want of waste and nutrition, the tissues becoming old and in- active. In some cases the pulse will be slow when the patient has remained quiet for some time, but is in- creased in frequency upon exertion. 318 STUDY OF DIAGNOSIS. These cases will be benefited by the use of small doses of Lobelia, Digitalis, or Ergot, with the use of means to stimulate increased waste and nutrition. Changes if* the character of the pulse are of very fre- quent occurrence, and many of them have already been named in connection with special remedies. In most severe diseases change in the character of the pulse will be found associated with frequency, and will prob- ably point out the sedative which will be found most useful. As heretofore stated, our examination of the pulse has reference to size, the movement of the mass of the blood, the impulse of the wave, its length, gen- eral character and termination, and the inter wave- current. A reference to any sphygmographic illustra- tions will show that there is very great variation in all of these, and that they do represent definite pathologi- cal conditions. Irregular distribution of blood is frequently met with in disease, and a popular expression in treatment is, " equalize the circulation." Some have laughed at the expression as being indefinite, unscientific, and partak- ing of the character of u old women's " medicine. But there is no plainer pathological fact than that the cir- culation of blood is unequal in many instances — here too much blood, there too little — a want of circulation to the extremities and surface, too much blood in the cavities of the body. That such inequality is the cause of disease is very easily shown by many examples. Every one will recollect the cold feet and chilled sur- face that attends an ordinary bad cold, and will recall the local and general wrong that comes from a similar condition at the period of the menstrual flow, xcvy greatly increased by the local stasis of blood in the STUDY OF DIAGNOSIS. 31S uterus if the flow should be stopped. Many can recall cases of chronic disease, associated with cold feet and a tendency to chilliness of the surface from imperfect circulation, and they will recollect that such cases were very intractable. Some will recall cases of pneumonia or of typhoid fever, in which an irregularity of the cir- culation, and a tendency to accumulation of blood in .the cavities, and a want of blood to extremities and surface were prominent features, and they will recall the gravity of such cases. As the mind recalls these well-known facts, the im- portance of equalizing the circulation will be seen. If in the commencement of a cold, means are employed to give an equally vigorous circulation to surface and extremities, the mucous membranes cease to suffer If in chronic disease we so improve the circulation that all parts receive an equal quantity of blood, we have ac- complished one of the essential things necessary to re- covery. If in severe local disease, or the graver acute affections called typhoid, we find an irregular distribu- tion of blood and heat, getting well will probably de- pend upon our ability to rectify this wrong. The Local Lesions of the Circulation that interest us most are embraced under the head of hyperemia, or an excess of blood in a part. This has special reference to the capillary circulation, though arteries and veins are involved to a limited extent. The condition of local hyperemia is easily understood and recognized. In health the mass of capillaries are not full, indeed it is impossible that they should be full at once. If there is an increased amount of blood in a part, with its motion unchanged, there will be increase of size— swell- 320 STUDY OF DIAGNOSIS. ing — redness, if the part is superficial, and increase of temperature and sensitiveness. Whilst it is possible to have the condition above nanied.it is uncommon. As a rule there is a change in the rapidity of the circulation as well. Thus we divide hypersemia into two varieties, active and passive — in the one there is excess of blood in a part with its move- ment increased, and in the other excess of blood in a part with its movement diminished. We call the first determination of blood, and the second congestion. It will not do to mistake these pathological conditions, as the treatment of one is almost the opposite of that of the other. The cause of determination of blood is one — irrita- tion — xibi ivrilatio ibi jiuxus ; and the condition of the part is one of excitation. The symptoms are very clear — there is swelling, heat, increased sensitiveness, and redness. In minor degree the functional activity of organs and parts is increased; but when in excess, though the part is excited, the function is diminished. If now we compare with this the condition of the capillary circulation in congestion, we will see that there is much difference. In this the capillaries are filled with blood, but the movement of the blood is sluggish, or entirely arrested in some vessels. The active life of the part is impaired to the extent of the impairment in the circulation, and all the expressions show dullness and want of functional activity. Whilst there wns but one cause for determination of blood, in congestion we may have three. The principal one of these is an impairment of the life of the part — the structures being enfeebled the capillaries yield to the visa (ergo of the blood. In some cases an irritation STUDY OF DIAGNOSIS. 321 of the part is a first cause, determining a greater amount of blood to it than its weakened vessels can withstand. In other cases an obstruction to the return current by way of the veins, is a principal cause. As before named, the symptoms are all of impaired function and oppression, and when we compare this with the excitation of the active state of determination of blood, the distinction will be clear. We say that the sensations are of fullness, weight, dullness, and if there is pain it will partake of these characters. The . objective symptoms when near the surface are of swell- ing, and an increased redness that has not the bright- ness of the active circulation ; the temperature may or may not be increased. If we take some examples of the two conditions, the subject may be clearer. In determination to the brain, there is a flushed face (bright), bright eyes, contracted pupils, increased temperature, and excitation of func- tion — the patient being excited, restless and sleepless. In congestion the face is usually flushed (dusky, pur- plish or livid), the eyes are dull, pupils dilated or im- mobile, the mind is sluggish and the patient inclined to coma. If we take the lungs, we find in determina- tion a rapid, uneas}' respiration, characterized by quick movements of the walls of the chest, and the patient shows the excitation in the sharp, forcible cough, and frequent change of position to get relief. The func- tional activity of the lungs being increased, the color of the blood when it reaches the surface is brighter than usual, and the surface is therefore flushed. In conges- tion, the movement of the chest is sluggish, labored and oppressed, and the cough has a like dull and oppressed character. The function of the lungs being diminished 322 STUDY OF DIAGNOSIS. the surface is inclined to be dull, dusky, or livid. If we take a. diarrhoea as an example, the symptoms are quite as clear. With determination of blood, there is marked uneasiness, and the evacuations are unpleasant or possibly painful, and attended with some tenesmus. From congestion, the bowels are tumid, have a sensa- tion of weight and fullness, and the discharges are free and without uneasiness. Whenever we find these two conditions, the symp- toms will have the same character, and will be shown by the sensations, and by the function of the part. In determination there is the feeling of increased activity, and in congestion the feeling of impaired activity; in determination there is excited function, in congestion impairment of function. As the cause of determination is irritation of the part, any agent which will remove this irritation becomes a remedy. As the circulation in its entirety is controlled by a system of nerves, a lesion of a part may some- times be best relieved by an action upon the whole through the sympathetic. Determination of blood to any part may be relieved by the use of Veratrum, Aconite and Gelseminum. Other than these general remedies, we select those that influence the special part affected, and that remove irritation. In determination to the brain we use Gelscminum ; to the lungs Vera- trum or Ipecac; to the kidneys Gelseminum ; to the bladder Eryngium ; to the bowels Aconite and Ipecac ; to the uterus Aconite and Macrotys. In so far as we use local applications they are selected in the same way: wet packs, poultices, fomentations, enemata, in- halations, etc., are selected with reference to their seda- tive character. STUDY OF DIAGNOSIS 323 In congestion the part requires stimulation, especially stimulation through the sympathetic. It may also be influenced to a greater or less extent by remedies stimulating the circulation at large. Thus Belladonna, Lobelia, and to some extent Aconite, are of value in all cases of congestion. Other remedies are selected with reference to their action upon the part, as stimulants or excitants. In congestion of the brain we use Bella- donna; in congestion of the lungs or of the heart, Lobelia ; in congestion of the abdominal viscera, Nux Vomica ; in congestion of the kidneys, Belladonna, etc. In selecting local applications we observe the same rule ; whatever their form, they should be excitant to the part. In studying the action of remedies, we first wish to know where they act, and second the kind of action. If a part is diseased, we wish a remedy that acts upon that part particularly, and which does that which is necessary to restore it to health. In the case of determination of blood — the active circulation — we want a remedy that will remove irritation, and the un- due excitation of its circulation ; in congestion we want a remedy that will increase the life of a part, or that will give the necessaiy stimulus to the capillary vessels. According to Dr. Williams, inflammation is a local hyperemia, with the movement of the blood partly in- creased and partly diminished. We study this process of disease, with reference to its cause, the lesion of the circulation, the exudation, and the result or termina- tion. The cause is one, irritation with such impairment of vegetative life. From the irritation comes an in- creased circulation to the part, the capillaries are filled with blood, which in some moves slower and slower, until the circulation through them is arrested ; and yet 324 STUDY OF DIAGNOSIS. in others the movement of the blood still continues rapid. As the capillaries lose their strength and be- come thus filled, the fluid portion of the blood is exuded into the intercapillary spaces, or upon free surfaces. This completes the pathological process, and we next study its result upon the life of the part. If the origi- nal lesion has not impaired the vegetative life too much, or the lesion of the circulation has not been too great, we find that after a time these minute vessels regain their tone, and the circulation is re-established in them. As the current of blood commences to flow through them, the material exuded is drawn into the current and carried away, thus leaving the part in its original condition. This termination is called "resolution," and is the result most to be desired in all cases. But if the life of the part be so impaired by the cause, that it can not renew itself; or if the impairment of the cir- culation be so great as prevent its receiving tho necessary amount of oxygen, and the removal of car- bonic acid gas, then it must die and be removed. This death and removal takes place in two ways — by sup- puration, and by gangrene or mortification. In sup- puration the process of death is modified by a lower form of life — the production of pus-cells, from the formative cells of the part, and thus the remainder of the body is protected in part, and repair facilitated. But if the impairment of life is greater than this, the part dies, and is removed en masse, by the suppurative process when the tissues still retain sufficient life. The symptoms of inflammation, according to the old authorities, are pain, heat, swelling and redness, and for superficial parts these are characteristic and definite, but for internal and concealed parts we are obliged to STUDY OF DIAGNOSIS. 325 rely uj^on the first, and the evidences of impaired func- tion, and the influence upon the general health. Pain is a very constant expression of inflammation, though it is very common from other causes. It varies from simple uneasiness from over-excitation, to the sharpest and most severe suffering, and its intensity is not to be taken as the measure of inflammatoiy action in anj^ case. It becomes symptomatic of inflammation only when there is evidence of a wrong circulation, and increase of temperature, general or local. Heat is a constant symptom, and much more reliable than pain. It may be but local in superficial inflam- mation, or when but a small and unimportant part is affected, but is general when an important part or much tissue is involved. In some cases the patient's sense of heat may be taken as evidence, though this is very liable to error. As a rule the temperature of an in- flamed part will not rise higher than 102°, unless there is a corresponding elevation in the temperature of the body, and there is rarely more than one or two degrees difference between the general and local temperature. The sense of heat, when the hand is placed upon a superficial inflammation, is due in part to arrest of secretion from the skin, which is also the cause of any difference there may be in temperature. Swelling is also a constant symptom, though not so marked when free surfaces are involved, or very "dense tissues. It is not a reliable symptom, however, for it may be due to changes in the nutrition of a part, to growths, deposits -.and exudations. To be of any im- portance in diagnosis it must be associated with evi- dences of derangement of the circulation, and with in- creased heat. 326 STUDY OF DIAGNOSIS. Redness is only an evidence in superficial inflamma tion, and is due to the presence of a large number of red globules. It is deeper than in determination of blood, though it may be simulated by some rarer con- ditions of the skin. Among the prominent and most valuable symptoms of inflammation are wrongs of function ; these are con- stant and characteristic. In the early stage of excite- ment the functional activity of some parts will be in- creased ; but in a majority it simply shows excitement and is really impaired. As the capillary stasis in- creases, and exudation occurs, the function becomes more and more impaired, until in some cases it is com- pletely arrested. Thus in inflammation of the brain, we have at first great mental excitement, then delirium, then probably incoherent (muttering) delirium, and finally from exudation — coma. In this case the symp- toms of the first and second stages are almost opposite — active delirium and coma. In inflammation of the lungs we find at first increased activity and a rapid oxi- dation of the blood ; but in the second stage there is oppression, and an imperfect aeration of the blood. In inflammation of the liver, there maybe at first stage an increase of biliaiy secretion, w T hilst in the second there is complete arrest. So in inflammation of the kidneys, the first excitement produces increased secretion of urine, whilst the second may arrest it entirely. The different phases of the inflammatory process and its results, require care in diagnosis. Recognizing the presence of an inflammation, we want to know the danger to the life of the part, and to the life as a whole. In this respect it may be said, that those cases of but moderate excitement are most favorable. When the STUDY OF DIAGNOSIS. 327 vascular and nervous excitement are extreme we may anticipate an unfavorable result, as well as when we have marked swelling and redness, with impaired sen- sibility and arrest of function. Tbe sensation given to the touch will be most reliable in external inflamma- tions; the greater the departure from the normal stand- ard, the greater the danger to the tissues. Suppuration is announced by an increased fullness of the tissues, a sense of increased tension, and a change in the character of the pain, which becomes throbbing. If but a moderate amount of tissue is involved in an unimportant part, suppuration is followed by relief of the general symptoms, but when considerable tissue is broken down, or important organs are involved, it is frequently ushered in with a chill, and attended by a fever having somewhat the character of hectic. Gangrene of external parts is announced by the change iu color — purplish or black — by coldness, and a want of sensibility. Internally it is announced by great prostration, the subsidence of pain, loss of sensi- bility, and a soft, feeble pulse. The general symptoms are those of fever. The cause of inflammation is depressing to the life of the indi- vidual as well as to the life of the part, and when con- siderable structures are involved the expressions are very distinct. The first influence gives the listlessness, languor and loss of function ; this culminates in a chill or rigor ; and this is followed by the symptoms of febrile reaction — frequent pulse, increased temperature, arrest of secretion, and derangement of the nervous system. In the severer cases of inflammation these general symptoms are as pronounced as in fever, and it is some- 328 STUDY OF DIAGNOSIS. times difficult to determine a local lesion, except by close examination and attention to special symptoms. If care is used, however, a special wrong of function will attract attention to a part or organ, and symptoms of inflammation will be detected. The close relationship between fever and inflamma- tion should not be forgotten, and indeed it is well in practice to recognize them as requiring the same treat- ment ; an inflammation is fever of a part. The reme- dies for fever are remedies for inflammation, and in many cases they are the best and most direct, we have. If, in the majority of cases, the pulse is brought down to a normal standard, the temperature reduced, inner- vation normal, and the secretions restored, the inflam- matory process will cease, and if the life of the part has not been too much impaired, resolution will be rapidly effected. In studying the treatment of inflammation it is well to bear in mind the different phases of the morbid pro- cess. First, irritation and determination of blood ; second, impairment of capillary circulation until its final arrest, and lastly, the impairment of the life of the tissues from this and the exudation. The irritation may continue through the entire progress of the in- flammation, and thus will continuously attract the blood to the part, Avhilst from the commencement there are marked evidences of impairment of tissue life. Anything that will lessen or remove irritation will prove a remedy in inflammation. Take away the irri- tation, and you take away the cause of an excited cir- culation of blood to and in a part. The general means have been already referred to, but some of them are local as well. The sedatives, Veratrum and Aconite. STUDY OF DIAGNOSIS. 329 influence the inflammatory process directly, wherever it may be located. So do the indirect sedatives of the olden time — the nauseant emetics, and the more power- ful diaphoretics. In the selection of local means, we must closely value the inflammatory process, and determine the kind of influence most desirable. It may be directly sedative, removing irritation, and in some instances maj r be depressant. In others, whilst an object is to remove irritation, we also keep in view the greater ne- cessity of stimulation to the capillary circulation. And in many we keep in view, as a principal object, such treatment as will increase the life of the tissues. When we have determined by an examination that the inflammation must terminate in suppuration, we should not forget that resolution goes on at the same time, and that it is our business to confine the suppu- rative process to as small a proportion as possible, and to obtain resolution as far as is practicable. The treat- ment is just the same as in mortification ; we wish to restrict the death to as small a portion as possible, and we do it by strengthening the life of the tissues. The means named are those which might be em- braced under the head of physiological medicine, and give us an excellent basis of treatment in man}^ cases. In some we have special means, the action of which can not be explained in this way. These remedies are indicated by some special expression of disease, and as we have already seen, they prove curative in very diverse (seemingly) conditions of disease. I need but instance the action of Tincture of Muriate of Iron in erysipelas ; the action of Rhus, Bryonia and Macro tys and some other agents in the arrest of special inflam- 28 330 STUDY OF DIAGNOSIS. mations, or the special action on individual parts or associate functions, as Phytolacca in mammary inflam- mation, or in. disease arising from nursing. INNEKVATION, We divide the nervous sj^stem into three parts, for study— the brain, the spinal cord, and sympathetic* The first is the organ of conscious life, the second of automatic movement, and the third governs and asso- ciates the functions of vegetative life. The functions of the brain are reason, emotion, volition and sensation ; of the spinal cord, the co-ordination of muscular action, and the functions of respiration, defsecation and urina- tion, and expulsion of the uterine contents ; and of the sympathetic, digestion, circulation, nutrition, and secre- tion and excretion. Lesions of innervation may be due to a change in the condition or structure of the nerve centres, or to some iesion external to these. The more common lesions are of the circulation, and we have them from the two opposite conditions of an excited circulation — too much blood in a part, or an enfeebled circulation — too little blood in a part. Whenever we find these legions, this is the first question we ask, and usually the symptoms of hypersemia or anaemia will be distinctly marked. A physiological treatment will be based upon this, to a considerable extent. If we have hyperemia we use remedies which lessen excitation, if it is anaemia we emploj 7 such agents as stimulate and give a more vig- orous circulation. In the first cases the treatment may be temporarily depressant, in the second it is always restorative and tonic. STUDY OF DIAGNOSIS. 331 Delirium in acute disease is readily recognized. The inability to reason rightly, and the illogical and unreasonable expressions tell the story clearly. We say delirium is active, it is passive, it is coherent, it is in- coherent — tailing the entire range of that active con- tinued expression, in which it is almost impossible to control the patient, to the dreamy delirium of typhoid fever, in which the patient is calm and still, or the mut- tering delirium that soon passes into coma. But we are not so much interested in the expression of delirium as we are in the symptoms indicating the physical condition of the brain. We want to know whether there is an active circulation, or an enfeebled one : whether the patient can bear temporary depres- sants, or requires stimulants and restoratives. The practitioner will recognize the pertinence of this in- quiry, as it points the way to the selection of direct remedies. In the first case we use the sedatives and ;iate means that relieve excitement, and the special remedy. Gelseminum. In the second we u^e Quinine, stimulants, restoratives, tonics and food. It may be remarked here, that in addition to the means selected in this way. any remedy which may be indicated by special symptoms, is a remedy for delirium. Thus we see a delirium rapidly disappear under the use of an acid, an alkali, one of the antiseptics. Rhus, and other agents heretofore spoken of. The two methods may be sometimes combined ; though, if the symptoms indicating a single remedy are pronounced it should be first given. In delirium tremens, we also find two conditions of the brain as a basis for the wrong reason. A want of re- cognition of this fact has given us some queer medical 332 STUDY OP DIAGNOSIS. literature. For a time we will find our medical peri- odicals teeming with recommendations of stimulants, tonics and food as the means of cure ; then for a time they will recommend a sedative and depressant treat- ment. It never seems to have impressed the profession that delirium tremens might arise from two opposite conditions of the brain — one in which the circulation of the organ is depressed, and the other in which it is too active — and yet this is very certainly the case. If we find our patient with sunken eyes, blanched or livid lips, cold extremities, and a small and feeble pulse, we know that he requires stimulants, and especially food. In the early stage of such a case we would ex- pect to arrest its progress by the stimulant action of Nux, Iodine and Hydrastis, and the use of beef-tea. We can see how it is that Capsicum in large doses should prove curative, and how small doses of Quinine, Opium and Camphor exert a beneficial influence. But if we find him with a florid face, full, bright eyes, increased temperature, and a full, hard pulse, we recog- nize a condition of undue excitement, and would hardly use the treatment just named, though it has proven successful in cases of delirium tremens. On the con- trary, we propose to select remedies which will remove the undue excitement of the circulation, and give rest to the brain. Thus we give full doses of Veratrum and Gelseminum, saline cathartics and diaphoretics, and possibly follow with Bromide of Potash and Chloral. If we study puerperal mania, or acute insanity, we find two classes of cases, as in delirium tremens. In one from exhaustive discharges, lactation, and starva- tion (the regulation toast and tea), we have a condition of anaemia. We find the face pallid, the eyes dull, the STUDY OF DIAGNOSIS. 333 tongue broad and pallid, the pulse small and feeble, and the extremities cool. We at once recognize that this patient wants proper stimulants, tonics, restoratives, and food, and as we give them we find that there is a stead}' improvement. If we had emploved the olden stereotyped treatment of purgatives and depletives, we would have had a funeral, or a case for the lunatic asylum. But in other cases we do find a flushed face, full, bright eyes, contracted tongue, increased temperature, a fnll, hard pulse, and partial arrest of secretion. The case is just as clear as the first one, and we cure it by the use of the proper sedative, Gelseminum, and means which will restore secretion and excretion. In this case temporary depressants may sometimes be employed with good results. In chronic mania, the diagnosis of the physical condi- tions of brain and body will be made in the usual way. All wrongs of function and structure are to be removed as far as possible, and the patient placed in the best possible health. Thus if there are special indications for any single remedy, this should be given. In some cases the action of such agents is very speedy and per- manent. With regard to the psychological treatment, but little need be said. It must be based upon this law of nature — "that in proportion as an organ or function is used it gains strength ; and as it is disused it loses strength." In so far as the morbid mind has material to feed upon, and has exercise, the insanity will be in creased ; and in so far as the normal functions of the mind are disused, they become enfeebled. The object, therefore, is, to call out the mind in orderly channels as 334 STUDY OF DIAGNOSIS. much as possible, and to give as little cause for the in- sane manifestations as possible, that the one may gain strength and the other lose it. What has been said with reference to reason is appli- cable to the emotions, in so far as the necessity of re- cognizing the physical lesions are concerned. Emo- tional wrongs have a physical basis, and if perfect health can be restored, they will pass away. Indeed, permanent cures can only be effected in this way. The wrongs of the emotions may be in either of the three ways — excess, defect and perversion — but the first and last associated, are usually met with. The expres- sion is so distinct that it can hardly be mistaken ; too great a manifestation and rapid alternation of grief, joy, hope, fear, exaltation, depression, etc., without sufficient or corresponding cause, tells the story. Hys- teria is the type of this class of diseases, though it in- volves other than the emotions. A defect in volition is often noticed as an element of mental disease, and as an attendant upon some other diseases. It is often remarked that the strong will is an important means of recovery — " that when one wills to get well, he will get well " — and every practitioner will have noticed the difficulty of managing those cases in which there was an indifference, or want of volition. The expression of the face will frequently give this in- formation before a word is spoken. The firm expres- sion of the muscles of the mouth and closure of the jaws is characteristic of strong will ; whilst the relaxed muscles of the mouth, and the general want of expres- sion, tells of enfeebled will. Eecovery will frequently depend as much, or more, upon strengthening the will, as upon the use of reme- STUDY OF DIAGNOSIS. 335 dies. If we can call it into action, by presenting addi- tional motives for its exercise, or by a judicious stimu- lation from attendants and friends, we find that it will grow by exercise, and that which was difficult to the patient at first soon becomes easy and natural. The brain receives impressions from the world with- out, and from the various parts of the body, through the apparatus and nerves of special and general sense — and this we call sensation. In the healthy body all sensations from it are pleasurable, and the use of the special senses is a source of pleasure. But in disease sensation is unpleasant, and a source of discomfort, and we designate it as pain. It is well to become thor- oughly conscious of this, by passing the various sensa- tions in review. To the sound eye, use is a pleasure, and we only know the organ through the pleasurable sense of vision ; the impulse of sound waves upon the ear is pleasurable; so is the use of the sense of taste, and of smell. When we direct the mind to the appa- ratus of digestion, we find that it gives pleasurable sen- sations, in so far as it gives sensation at all ; the func- tion of respiration is pleasurable, and so is defalcation and urination. When this sense of pleasure is lost, we may know that an organ or part is diseased, though the discomfort may not tell us the quality or amount of disease. If the use of the eye becomes a source of discomfort, our attention is called to that organ as the seat of disease, and we at once make a proper examination to deter- mine its character. If the use of the ear is a source of discomfort, we at once conclude that it is the seat of disease, and we make the necessary examinations to determine its exact character. If there is discomfort 336 STUDY OF DIAGNOSIS. in the sense of taste, we know there is a wrong in the mouth where these nerves are distributed, or of the digestive apparatus to which these- nerves stand sen- tinel. If there is discomfort in the sense of smell, Ave at once conclude there is disease of the nasal cavities. So when there is discomfort from any apparatus or function — the throat, larynx, lungs, stomach, bowels, defecation, urination, etc., we know there is disease, and having our attention directed to its seat, we pro- ceed with the proper examinations to determine its character. Persons will sometimes have their first knowledge of organs or functions through discomfort and pain. The dyspeptic realizes that he has a stomach through pain ; the minister realizes that he has a larynx, when it has become irritable and painful by abuse ; the location of lungs, liver, spleen, bowels, kidneys, bladder, uterus, etc., is first realized by many through the suffering of disease. It is well to bear in mind that pain may have two causes — it may be due in principal part or in whole from disease of the part that suffers, or of the brain that re- ceives the impression. To determine this is an impor- tant part of the diagnosis of pain. A little care in noting the expression of the face, the eyes, and the other functions of the brain will determine this in most cases, and this may be supplemented by a careful ex- amination of the part. The diagnosis between the pain of structural disease and neuralgia is usually made with ease. The absence of heat, redness and swelling, in any considerable de- gree, is usually sufficient, but in obscure cases it is well to cany the examination further to determine lesions of the blood, of nutrition, waste and excretion. STUDY OF DIAGNOSIS. 337 General disease will give rise to the conditions of pain, and to a considerable extent may be considered its cause. Thus, the vascular excitement and increased temperature of fever render the brain more sensitive to impressions, and the nerves more active purvej r ors. The symptomatic fever that attends inflammation has the same influence in increasing pain. Thus, in those cases where pain is very severe, the means that lessen the frequency of the pulse, diminish the temperature, and establish secretion, are the most effective to cure pain. When we study the condition of the brain as a cause of pain, we find that it is not one, as generally sup- posed, but two, possibly three. In one case we have evidence of vascular excitement in the flushed face, bright eyes, contracted pupils, and increased tempera- ture. And we meet this condition with Gelseminum, the sedatives, and possibly the saline diuretics and cathartics. In the second case we find the evidence of an enfeebled circulation in the pallid, expressionless lips, the dull eyes, dilated or immobile pupils, and pos- sibly the coolness of nose, ears and forehead — the gen- eral expression is of want of stimulus. In these cases we think of nerve stimulants, of Belladonna, Quinine, Xux, Ammonia, etc. The feeling of dullness and in- clination to sleep attending some forms of pain is met especially by Belladonna and Ergot. The wrongs of perversion are not so easily determined, but with care we may find the indications for special remedies, some- times in the expression of the face, sometimes in the appearance of the tongue, and sometimes in the changes of the pulse. There is no doubt that many times the character of 29 338 STUDY OF DIAGNOSIS. the pain may point out the special remedy for the cure of the disease, though it is not as certain as other mean3 of diagnosis. If we could feel the pain, as we feel the pulse, it would be different, but trusting to the patient's uneducated senses, and his imperfect power of analysis and expression, we find it uncertain. If per- sons are trained to close observation, analysis and ex- pression in this regard, as in some Homoeopathic fami- lies, it may become very reliable. Lesions of spinal innervation are diagnosed from wrongs of function controlled by this nerve-center. Thus impairment of muscular motion may be referred to an enfeebled spinal cord, an exalted sensibility of muscles, to increased spinal innervation, whilst all forms of convulsion may be attributed to perverted spinal innervation. Among the important functions controlled from the spinal cord is that of respiration. We will sometimes find deficient respiration, that phy- sical examination will determine is not from structural disease, and we reach the conclusion that it is want of innervation. In acute disease we sometimes find this so marked, that respiration can not be carried on except through the influence of the will and the external re- spiratory muscles. We notice that so soon as the patient sleeps, respiration becomes more and more dif- ficult, until at last he is suddenly aroused by a feeling of asphyxia ; thus rest is prevented, and death may re- sult. In all these cases we think of spinal stimulants as remedies, Nux Vomica and Strychnine being the t} r pe — and increasing spinal innervation, we find our patient breathes better, and gets necessary rest. The lesions of excess are rather rare, but still they deserve close study. We will find it marked in some STUDY OF DIAGNOSIS. 339 cases by excessive muscular irritability, so that the patient exhausts himself by over-exertion, or more fre- quently by that uneasiness which might be called mus- cular fret. In others the lesion is principally manifested In the respiratory muscular apparatus, giving frequent or irregular respiratory movements — respiratory fret — or sometimes severe and intractable cough from very slight internal irritation. In other cases we find the evidence in defecation and urination, giving frequency and some tenesmus, without corresponding internal disease. In these cases there is usually hyperaemia of the cord, marked by a full, hard pulse, tense skin and muscular structures, and rigidity or contraction in all the expres- sions of the body. The remedies will be Veratrum, Gelseminum, Sulphur in free doses, the saline cathartics and diuretics, the cold wet-sheet pack, alkaline batL, etc. In some rare cases, there is a condition of anaemia, and the patient requires Nux, Strychnine, Quinine, Iron, Arsenic, stimulant baths, with restoratives and animal foods. The lesion of perversion gives us the entire series of convulsive affections, so frequently met with in the practice of medicine. In this case the spinal cord takes complete control of the body, and sets it into disorderly movement. How the wrong is produced, or what is its exact character, is not known, but when once it has obtained, the tendency is to its repetition. There is no difficulty in its recognition ; the complete arrest of the function of the brain, and the disorderly activity of the muscles is so marked that it can not be mistaken. Two causes of convulsions are recognized : the one 340 STUDY OF DIAGNOSIS. disease of the spinal cord itself — intrinsic, the other a lesion of some other part — extrinsic. The exact condi- tions of the spinal cord are not well known, but we may recognize one of vascular excitement, and one of atony and impaired circulation. In the first the surface and face is flushed, the eyes bright and pupils con- tracted, the pulse somewhat full and hard, and the tem- perature usually increased. In the other the face is pallid or livid, the eyes dull, the pupils dilated in the intervals of spasm, the extremities cold, and the pulse small and frequent. There is a third case in which there is very evident congestion of the cord, and the face will be full and dusky, the eyes protruding, and the pulse full and oppressed. These cases are usually so well marked that the diag- nosis is not difficult, and a correct treatment is at once suggested. In the first case we use Gelsemjnum or Veratrum, or both. In the second case we use Lobelia, Chloroform, Bromide of Ammonium, or the foetid gum resins. In the third case, Belladonna, Ergot, and pos- sibly Aconite; Bromide of Ammonium is sometimes an excellent remedy here. It is most absurd to think of treating all cases of convulsions with one prescription. Specific Medication never goes that far, it treats conditions of disease, and not names. The instance of convulsions furnishes a very good example of the necessity of accurate diag- nosis. It is well to note here that the spinal cord having formed a habit of convulsive action, lias a tendency to repeat this at varying intervals, even though no change of structure, or disease of other parts can be found to account for it. In addition to the treatment for the STUDY OF DIAGNOSIS. 341 convulsions, this habit, or tendency to recurrence is to be broken up, and we find in many cases that the longer the convulsive action can be postponed, the less disposition there is to its recurrence. In the treatment of some cases of epilepsy, this is a principal object, and any means which will even temporarily ward off an attack, becomes a part of the cure. The extrinsic causes deserve consideration, though many times they have ceased before we are called to treat the cases. If in infancy we find the gums swollen and purplish, a free incision over the coming tooth may relieve the convulsion at once. If green fruit or other irritant ingesta has proven a cause of convulsions through irritation of the stomach, an emetic will give the speediest relief. If it has come from irritation of the solar plexus, attended by pain — colic — ISTux Yomica will give relief. If from irritating materials in the intestine, cathartic enemata ma} 7 be of great service. If from partial suppression of urine, the hot pack over the loins, with Geiseminum, will be the treatment. Worms may be a cause of convulsions, and yet I do not think it advisable to give worm medicines, until all symptoms of nervous irritation and convulsions have been removed. Otherwise the additional irritation from the worm medicine may prove fatal. In epilepsy the original cause may pass away in a few hours, or it may persist for years. Thus in some cases an epilepsy will arise from a temporary irritation of the stomach, the intestinal canal, or the reproductive apparatus, and no traces of the lesion will be found when we are called to treat the patient. But in other cases the lesions will persist, and their occasional or periodical increase will determine the convulsion. Thus, 342 STUDY OF DIAGNOSIS. menstrual derangement may prove a continuous cause, as will disease of kidneys, stomach, bowels, and some other parts. In all cases the examination is careful \y made to detect local lesions, and when found, means are employed to remove them as part of the cure. The study of paralysis might follow the consideration of the lesions of the brain and spinal cord, as it may embrace either or both. When the lesion is of one of the hemispheres of the brain, the paralysis is of one- half of the body, divided vertically, and is called hemi- plegia. When it is of the spinal cord, it is of the lower portion of the body, the division being horizontal, and involves all parts below the seat of disease ; this is called paraplegia. When of but limited extent, we call it local paralysis, and we trace it to a lesion in the course of the nerves, or to a limited disease of the cen- tre from which the nerve has its origin. We must not suppose that when we have diagnosed a paralysis by the impairment or total loss of motion or sensation, or both, that we are ready to make a pre- scription, and that all that is necessary to be done is to stimulate the nerve centres or the affected parts, by Strychnia, or electricity. We want to know the char- acter of the wrong, both of the nerve centres and of the general health, and when we have determined this we can prescribe intelligently. In hemiplegia we will find two conditions of the brain. In one case we will have a flushed face, bright eyes, contracted pupils, increased temperature, im- paired excretion, and a pulse characterized by fullness and hardness. Surely no sane person would treat this case with Nux or Strychnine? On the contrary, we use the proper sedative, Gelseminum, means to establish STUDY OF DIAGNOSIS. 343 secretion, and possibly suppurative counter-irritation. In a second case the face is swollen and dusky, the lips livid or purple, the eye dull, pupils dilated or immobile, and the pulse full and oppressed. This patient wants Belladonna, Ergot, Bromide of Ammonium, and wet- cups to the spine, with, possibly, stimulating cathartics. In a third case the head is cool, the face lacks expres- sion, and the pulse is nearly normal, but wants force. Every symptom points to anaemia of the brain, and to the want of restoratives. Here we give Nux or Strych- nine as nerve stimulants, the bitter tonics, good food, and use electricity for its stimulant influence. The diagnosis will take the same course in acute paraplegia, and the same means will be used in its treat- ment. When it has been preceded by an injury, or b}" inflammation, we wish to determine as nearly as pos- sible the condition of the part, and whether or not the lesion has destroyed the nerve structures. Even here the treatment may be rational. We do that which needs doing, whether it be to promote the removal of effusion of organized lymph, or of water, or by an in- crease of waste and nutrition gradually renew the dis- eased structures until they are capable of doing their work. Wrongs of the sympathetic nervous system are so in- timately associated with lesion of the vegetative func- tions that we find difficulty in separating them. Pos- sibly it is only where an important part or the whole of this system is involved, that it requires special study. We may classify these lesions as an excess, defect, or perversion, though the excess is more an undue excita- tion than an increase of power. We will find this excess marked in an unnatural and 344 STUDY OP DIAGNOSIS. unaccountable frequency or hardness of pulse, and an unpleasant irritability of the organs of digestion and secretion. There can be no improvement until we can have better innervation. In such cases Veratrum has a most excellent action, and followed by Arsenic, will frequently effect cures in very stubborn cases. Defect is marked by a feeble circulation, the artery giving the sensation of a want of tone or elasticity, and all the vegetative functions are feebty and imper- fectly performed. That it is not due to a wrong of the organs themselves is readily determined by other symp- toms. In these cases, Phosphorus, Sulphur, Iron, Cod Liver Oil, Pulsatilla, Digitalis, Aconite, are especially indicated, the particular remedy being selected by spe- cial symptoms. Perversion of sympathetic innervation is shown by irregularity in the performance of the vegetative func- tions, and by changes in the character of the pulse, other than frequency, strength, or feebleness, The remedies will be selected, as named in the first part of the work. The association of the sympathetic with the spinal nervous system gives us that condition of disease known as spinal irritation. It is of frequent occurrence in chronic disease, and when marked is sufficient to pre- vent a cure by the ordinary means, being a continued source of wrong innervation. It is a little singular that the source of this lesion of the spinal cord should always be an organ supplied from the sympathetic, and that irritation should be so readily propagated back- ward along these nerves. Yet it is a fact that a dis- ease of irritation can not exist long in an organ with- out some disturbance of the great sympathetic, and the STUDY OF DIAGNOSIS. 345 spinal cord immediately behind the ganglion, that fur- nish the nervous supply. Spinal irritation is usually marked by tenderness on pressure over the bodies of the vertebrae, and when such tenderness is found, it is taken as evidence of this lesion. But once in a while we will find the evidence at some distance from the spine, but always in the course or termination of the posterior spinal nerves. It has been proposed by Prof. John King, to deter- mine the locality of chronic visceral disease, by an ex- amination of the spine, and this can be done where there is spinal irritation. If the reader will refer to a text-book on anatomy, he will see that the distribution of sympathetic nerves, and connection with the spinal cord is very simple. The sympathetic ganglia send off large nerves, which before their distribution form a net- work, called a plexus, and from this the nerves are dis- tributed upon the nearest arteries. Thus if we know the source of nerve supply to a plexus, and the distri- bution of the arteries nearest to this, we will readilv make the association between a particular part of the spinal-cord, and a special organ or organs. It might be remarked that the connection between the cord and the ganglia which lie upon the bodies of the vertebrae in front, is immediately backward and forward by fila- ments of communication, and that a limited portion of the gray substance of the cord is thus associated in action with a ganglion. The first cervical ganglion sends its branches upwards on the carotids, to supply the brain andL the organs of special sense ; and a nerve downward, which through the cardiac plexus is distributed to the heart; thus to a certain extent associating the brain and heart in action. 346 STUDY OF DIAGNOSIS. The other cervical ganglia, send nerves downward to the cardiac plexus, which supplies the heart, and to some extent the lungs. The upper dorsal ganglia send off the great splanchnic, which passing through the diaphragm form the solar plexus, and from this the nerves are distributed upon the cceliac axis to the stomach, liver and spleen, and upon the superior me- senteric to the small intestine and pancreas. Branches from this pass downwards upon the spermatic artery to the testes in the male and the ovaries and uterus in the female. The lower dorsal ganglia furnish the lesser splanchnic nerves, which form above the renal arteries the renal plexus, and furnish nervous suppty to the kidneys, ureters and bladder. The dorsal ganglia fur- nish nerves for the formation of the hypogastric plexus, which gives nervous supply to the pelvic viscera. The sacral ganglia furnish nerves for the sacral plexus, which supplies some parts at the outlets of the pelvis, and the lower extremities. The above is but a brief synopsis of this subject, and the reader will do well to give it a thorough study, and trace out the distribution of these nerves on an anatom- ical plate. It will be found that there is a free inter- communication between different parts, some more especially than others, and thus many sympathies ob- served in health and disease can be accounted for. In the olden time we were in the habit of recom- mending the irritating plaster for all these cases, and though unpleasant, it may be employed with advantage in a great many. It is better, however, to determine more exactly the condition of the cord, as quite surely it is not always the same. Possibly our old division will serve our purpose here, classifying them with refer STUDY OF DIAGNOSIS. 347 ence to the circulation — a, with vascular excitement; h, with enfeebled circulation, or spinal anaemia. The case of vascular excitement will be shown in the bright eyes and contracted pupils, slight increase of temperature, and a pulse that has hardness and undue vibration as an element. It is especially the case for suppurative counter-irritation over the site of tender- ness, though I prefer, as being much pleasanter, the use of the wet-pack, of water, vinegar, or water acidulated with Sulphurous Acid. The internal remedies will em- brace Veratrum, Gelseminum, Bromide of Potash, and these may be aided by means to establish secretion. The case of anaemia of the cord will be recognized by the dull, sunken eye, feeble circulation to the sur- face and extremities, and a pulse that wants strength. In many of these cases the skin is relaxed, and there is undue exudation. These cases may have the irritating plaster used to rubefaction, stimulant frictions, rubbing of the spine with salt water, the use of electricity (Faradization) and means of a similar character. In- ternally the remedies will embrace Nux, Ergot, stimu- lant doses of Iodine, Pulsatilla, Bromide of Ammonium, and if the pulse is small and vibratile, Ehus. There are a few cases, marked by a full, sluggish, and oppressed pulse, dull eye and dilated pupil, in which Belladonna and Ergot will prove very efficient internal remedies, and in which a Belladonna plaster is the best local application. 348 STUDY OF DIAGNOSIS. NOSOLOGICAL CLASSIFICATION. The stucty of this is beyond the scope of this little volume, and the reader is referred to works on the u Practice of Medicine," or special treatises on diag- nosis, in which this classification is the basis. Our study has been wholty with reference to the selection of remedies, and the ordinary nomenclature interests us only as it points us to groups of remedies. The stud}' of nosology is of some importance in enabling one to give appropriate names, in writing or conversing of disease, and especially as satisfying the friends of a patient, who are always desirous of having a disease named. If the reader will take the classifica- tion given, and apply the methods of examination named through this work, he will find but little diffi- culty. We will pass it in brief review, pointing out the method of studj^, and giving the most pronounced symptoms. Chlorosis. — In the early menstrual period, usually before the age of twenty ; is characterized by want of blood, impaired nutrition, loss of flesh and strength, and differs from anaemia only in a greenish coloration of the otherwise blanched and bloodless skin. The name has no meaning in selecting remedies, unless in some cases, the peculiar shade of green would indicate Cop- per, and in others Sulphate of Alumina and Iron. Scorbutis — Is caused by a want of vegetable food, and is especially marked by softened and spongy gums, usually of a deeper color than natural ; and, finally, by a tendency to deliquescence in all tissues of low organi- STUDY OF DIAGNOSIS. 349 zation, espcciall} 7 cicatrical tissue. The name indicates a special pathological condition, and calls for vegetable acids (Citric Acid or lemon juice), and for vegetables, especially those containing a considerable amount of Potash. Dropsy — Has different causes, which require special study. It is characterized by exudations of water into the cellular tissues — oedema, anasarca ; or into the serous cavities — ascites, hydrothorax, hydropericardium, hydrocephalus, hydrocele, and hydrops articuli. The diagnosis is made b} r the touch, which gives a different sensation from growths, deposits, or accumulations of pus, blood, or gases. It refers us to special remedies, Apocynum, Aralia, and the hydragogue cathartics and diuretics for the removal of the accumulated fluid. Diabetes Mellitus. — Increased flow of urine, with loss of flesh and strength, and impairment of every function. Examination of the urine, as named under that head, determines the presence of sugar. The name does not point to remedies, which must be selected with reference to the symptoms in each individual case. Pyemia. — A condition of blood simulating suppura- tion in solids, usually having its origin in injuries or wounds of loose, non-vital tissues, though it may arise from wounds of any part in which putrescency develops. The condition may be known by the extreme restless- ness, and fear of a fatal result, a small, tremulous pulse, (sometimes the pulse has its usual inflammatory condi- tion until a short time before death), a peculiar con- striction of tissue about the base of the brain, pinched nose, and a general expression of irritability. It points 350 STUDY OF DIAGNOSIS, us to antiseptics and good food, as the means of cure. Opiates should not be used to relieve pain, if it is pos- sible to get along without them. Tuberculosis. — The impairment of the blood that gives rise to aplastic and cacoplastic deposits, has already been described. There is impairment of diges- tion, blood-making and nutrition, with loss of flesh and strength, local symptoms indicating the situation of the deposit. The treatment is suggested by the above description — increase retrograde metamorpho- sis and excretion, and remove the low albuminoid mate- rials, and improve nutrition. Fever. — The different forms of fever have been de- scribed in a preceding classification, and it is only necessary here to call attention to the principal phe- nomena, and the treatment. A fever is a disease of four stages — forming, cold, hot and sweating. The symptoms of the first are of prostration — there is an impairment of life. In the second this impairment is still greater, especially of innervation and circulation, and the patient feels cold. In the third vascular and nervous excitement are marked, the pulse is frequent, the temperature increased, the secretions partially arrested, and the vegetative functions impaired in pro- portion to the severity of the disease. In the fourth stage, the various functions are restored, and excretion established — it is convalescence. Whether a fever lasts a day or a month, it has these symptoms, with addi- tional ones showing a wrong of the blood. The treatment suggested is very plain. In the form- ing and cold stages means to increase the life, and espe- cially to stimulate the nervous and vascular systems. STUDY OF DIAGNOSIS. 351 In the hot stage, to reduce the frequency of the pulse, the temperature and excitation of the nervous sj^stem, and to increase excretion and the vegetative functions, employ such means as will check destruction of the blood, or that will neutralize any morbid element in it. Local Disease. — Local disease is determined by the unpleasant sensations in the part, experienced by the patient; by change in its functional expression; and by an examination with our senses, and the application of any instrumentality that medicine affords. The distinction between functional and structural disease is determined by the careful examination of the physician. In functional disease we expect to find little or no change in the physical properties of the part; in structural disease such changes will be de- tected The Brain, — Disease of the brain is shown by un- pleasant and painful sensations experienced in the organ, a change in the expression of the face and body, and changes in its functional expression. The charac- ter of the disease will be diagnosed by symptoms already pointed out. It suggests the use of brain remedies, in addition to a right general treatment. As examples we may name Gelseminum, Belladonna, Pulsatilla, Opium, Bromides of Potash and Ammonium, Phosphorus, Cypripedium, Camphor, Nux, Quinia, Ehus. The Spinal Cord. — Disease of the spinal cord is shown by unpleasant sensations experienced in the spine by the patient, by wrongs of muscular movement, respiration, etc. The same remedies are employed as for the brain a 352 STUDY OF DIAGNOSIS. Of the Nose. — Unpleasant sensations in and change in secretion of the nasal mucous membrane. Remedies that influence mucous membranes. Pharynx. — Sore throat, with unpleasant sensations in deglutition and respiration. The throat can be in- spected and changes of structure noted. Larynx. — Unpleasant sensations in the part ; change in the voice; difficulty of respiration ; cough; sputa; and change in* the sounds on auscultation. Special remedies, Aconite, Spongia, Antimony, Collinsonia. Bronchia. — Unpleasant sensations in the thorax; difficult respiration ; cough ; sputa; and change in the sounds heard on auscultation — blowing. Treatment will be general, and remedies that influence mucous membranes. Lungs. — Unpleasant sensations in the thorax ; diffi- cult respiration ; cough; sputa; sounds heard in aus- cultation — crepitant; percussion gives dullness when consolidation has taken place from any cause. Reme- dies, Aconite, Ipecac, Lobelia, Drosera, Agrimonia, Phosphorus. Heart. — Unpleasant sensations in the* prsecordia; sense of oppression and impending danger ; change in the pulse; and impairment of the circulation. Special remedies, Veratrum, Aconite, Digitalis, Cactus, Pulsa- tilla, Rhus, Bryonia. Pleura. — Pains of a sharp, lancinating character; difficulty in inspiration; cough; no change upon aus- cultation except in rare cases ; dullness on percussion from effusion. Remedies are all general, unless we ex- cept Bryonia and Asclepias. STUDY OF DIAGNOSIS. 353 Mouth and Salivary Glands. — Unpleasant sensa- tions, especially on taking food ; on exposure structural lesions can be seen and felt. Special remedies, Mer- cury, Iris, Podophyllin, Phytolacca, Collinsonia. (Esophagus. — Difficult deglutition. Eemedies gen- eral, except for nervous dysphagia, Pulsatilla. Tonsils. — Uneasy sensations in the throat ; difficult deglutition and respiration ; can be inspected and changes in size and form noted. Eemedies, Aconite, Nitrate of Potash. Stomach. — Unpleasant sensations in the region of the stomach, and impairment of function. Special remedies, Hydrocyanic Acid, Bismuth, Muriatic Acid, Lactic Acid, Pepsin, Hydrastis, Podophyllin, Leptan- drin, Nux, the class of emetics. Small Intestine. — Uneasiness in the abdomen ; im- pairment of digestion ; diarrhoea. Special remedies, Bismuth, Podophyllin, Nitric Acid, Hydrastis, Nux, Agrimonia, Epilobium, Aconite, Ipecac, a part of the class of cathartics. Large Intestine. — Uneasiness in the abdomen; tormina ; tenesmus ; and small, non-faecal evacuations. Special remedies, Aconite, Ipecac, Aloes, Colocynth, Hamamelis, Collinsonia. Liver. — Unpleasant sensations in right hypochon- drium, with occasional slight change in form and size ; impairment of digestion ; and changes in the color of the skin. Special remedies, Leptandra, Nux, Nitric Acid, Sulphur. 30 354 STUDY OF DIAGNOSIS. Spleen. — Unpleasant sensations in left hypochon- drium; change in form and position of the organ de- termined by the touch ; and impairment of blood-mak- ing and nutrition. No special remedy unless it be the Uvedalia. Peritoneum. — Sharp, lancinating pain in the abdo- men, increased by pressure, motion or respiration, with small, wiry pulse, if inflammatory. No special reme- dies. Supra-E-enal Capsules. — But one disease known— Addison's — characterized by bronzed discoloration of the skin, gradually increasing, and associated with im- pairment of the vegetative functions. No remedies known. Kidneys. — Unpleasant sensations in the lumbar re- gion near spine, in the urinary apparatus below, and in micturition ; changes in the urine determined by ex- amination ; and an influence upon the nervous system by retained urea — excitation at first, coma following. Special remedies, G-elseminum, Belladonna, and the class of diuretics. Bladder. — Unpleasant sensations behind the pubes; perineal pressure ; difficult and painful micturition ; and the presence of its secretion, mucus or pus, in the urine. Special remedies, Eryngium, Apis, Phosphorus, Hydrangea, Agrimonia, Staphysagria. Prostate Gland. — Unpleasant sensations in the peri- neum; difficult and painful micturition; and an ex- amination externally and by rectum determines change in size and sensibility. Special remedies, Staphysagria, Hamamelis, Phosphorus, Pulsatilla. STUDY OF DIAGNOSIS. 355 Urethra. — Unpleasant sensations in passing water ; discharges. Special remedies, Cannabis Indica, Copai- ba, Cubebs, Macrotys, Sandal Wood. Testes. — Unpleasant sensations in ; changes in size and form. Special remedies. Phytolacca, the Bromides, Pulsatilla, Staphysagria, Phosphorus, Iodine. Ovaries. — Unpleasant sensations in the iliac regions ; change of size and sensibility to the touch ; and wrongs of the reproductive function. Special remedies, Ma- crotys, Actea, Caulophyllum, Pulsatilla. Uterus. — Unpleasant sensations in the pelvis ; change of size and form ; change of position ; change in the menstrual and reproductive functions by the discharges ; change in the tissues determined by the touch and by sight. Special remedies, Ergot, Macrotys, Caulophyl- lum. Vagina and Yulva. — Unpleasant sensations ; by the discharges ; and by an examination by the touch and speculum. Special remedies, those which influence the reproductive function ; other remedies such as influence mucous membranes, and the general health. Arteries.— Changes in the sensation given to the touch, and impairment of the circulation. Special remedies, the same that influence the heart. Veins. — Change in size, form, course, and in their color. Special remedies, Hamamelis, Ergot, Iron. Lymphatic Glands. — Changes in size, in tempera- ture and in sensibility; with special impairment of the 35G STUDY OF DIAGNOSIS. blood, and of nutrition in some cases. Special reme- dies, Phytolacca, Iris, Stillingia, Alnus, Scrophularia, Iodine, Bromine, Phosphorus, Arsenic. Skin. — Unpleasant sensations ; changes in structure determined by examination. Special remedies, diapho- retics, Arsenic, Phosphorus, Sulphur. Eye. — Unpleasant sensations ; wrongs of function. Special remedies, Belladonna, Calabar Bean, Gelsemi- num, Opium, Bhus, Macrotys, Cannabis Indica, Arsenic. Ear. — Unpleasant sensations ; wrongs of function. No special remedies. Bones. — Unpleasant sensations ; change of form, size, sensibility, and impaired use. No special remedies. Muscular Tissues. — Unpleasant sensations in move- ment ; changes in size, form and sensibility. Special remedies, Macrotys, Apocj-num, Bryonia, Sticta, Phyto- lacca, Colchicum, Potassae. Articulations. — Unpleasant sensations ; changes in form, size and sensibility. No special remedies, except possibly Bryonia and Macrotys. Cellular Tissue. — Symptoms of inflammation, sup- puration. Special remedy, Lime. We have passed most of the organs and tissues in review, in order to impress the fact that remedies do act on special parts. Only a few remedies have been named as examples, but the reader is advised to make notes of remedies under the various heads as they come to his notice by reading or experiment. It must prove STUDY OF DIAGNOSIS. 357 of value in therapeutics, to be able to at once associate a group of remedies with special parts and functions, as having them thus clearly before us we can better choose the individual remedy applicable to the case in hand. Much more might have been written on this subject, and I doubt not the reader will feel that a more minute examination of local disease would have been profit- able. Yet there are many authorities who give this information, and as said before, it is beyond the scope of our work to make this study. Something must be left for each reader to think out for himself, (and this is really the most profitable study), and I have endeavored to point out the way, and give subjects for such thought. The physician who does his own thinking will always have the largest measure of success, and the greatest pleasure in and from his work. INDEX OF REMEDIES. In appending an index of remedies, I desire to point out the prominent indications for their use, whilst reference is made to the pages where the agents are noticed. "With some of the agents this index will be quite a complete study, and as the reader has all the special indications before him, he will be better able to group them together. So in the study of individual remedies, I thought it would be better to so arrange the index that the reader might do his reading with reference to the one agent; or when using it as a work of reference, he would be pointed to the special feature he desired to study. Acids, Indicated by deep redness of tongue and other parts freely supplied with blood, 80, 81, 102 Slick tongue 103 In stomachic digestion 271 Acid Acetic, Indicated by deep redness, zymosis 81, 102 Lactic, Indicated by deep redness 81 Tissues pinched and stringy 143 Eructations from stomach 112 Sepsis Ill Gastric digestion. 272 In diseases of the stomach 353 Muriatic, Contraction of tissues 65 Deep redness of mucous membranes 81 " and condition of stomach 102 Slick tongue 103 360 STUDY OF DIAGNOSIS. Acid, Muriatic, Sepsis , Ill Eructations from stomach 112 Hot breath, pungent 199 As an epidemic remedy 221, 227 Typhoid symptoms 238 Pungent heat 263 Gastric digestion 272 In diseases of the stomach 353 Nitric, Irritation of sympathetic 65 Yiolet color 82, 103 To influence the temperature 166 As an epidemic remedy 229 "Whooping' cough ,.. 230 To influence the pancreas 293 Sulphurous, Color muddy or dirty 83 Erysipelatous redness, blanched 90 Dirty tongue.... 104 Increased secretion of saliva Ill Large pulse, empty 153 Mawkish odor from excreta 198 " u breath 199 As an epidemic remedy 227 Zymosis 231 Typhoid symptoms 238 Pungent heat 273 Aconite, Illustrating the certainty of medicine 15 Inflammation of brain 62 Effusion, with bright eyes 63 Constriction about temples 65 Shrunken face 66 Simple increase of color 78 Vascular excitement 79 Constriction and thinning of structures 84 Elongated and pointed tongue 95 Contraction of tongue , 106 Eructations from stomach 112 Contraction and irritability of muscular tissue 142 Small pulse 153 INDEX. 361 Aconite, Epidemic remedy ... 227 To influence the nerve centers 263 Tongue, redness of tip and edges 269 Contracted slick tongue 272 To inflnence the pancreas 293 To influence secretion . 299 To influence the kidneys 304 Frequency of pulse , 317 Determination of blood 322 Congestion 323 In inflammation 328 To influence sympathetic innervation 344 In diseases of the larynx, lungs and heart 352 In diseases of the stomach and intestinal canal 353 Acetate of Potash, Sensation of fullness without elasticity... 143 To remove bile pigment 290 Alkaline Salts, Pallid tongue 101 Acidity of stomach 211 Potash, Muscular wrongs 102 Alcoholic Stimulants, Oppressed voice, hollow and unsteady, 174 Small, soft pulse 153 Asclepias, Rubeola, measles 229 Apis, Surface hot, burning, painful, dry 231 In disease of the bladder 354 Aralia, A remedy for dropsy 349 Ammonia, Enfeebled capillary circulation 79 Scarlatina 229 As an antidote 247 As a cerebral stimulant 337 Actea, Pinkish color 86 In the treatment of disease of the ovaries 355 Arsenic, White line around mouth, dragging down of corners, 85 Tongue large, thick in center, incurved edges 103 Dull and opaque skin 93 Increased secretion of saliva Ill Pinched, contracted tissues 144 Open, tremulous pulse 154 Feebleness of voice 174 31 362 STUDY OF DIAGNOSIS. Arsenic, Influence upon the temperature 261 Defect in excretion from the lungs 297 Anaemia of the spinal cord 339 In the treatment of diseases of the skin 356 Alnus, In disease of the lymphatic glands 356 Apocynum, Fullness of eyes, fullness of face, drawing down of corners of mouth 62 Dull eyes and relaxation of face 63 Full eyelids 66, 84 Full pulse, doughy, accompanied by muscular pain... 153 (Edema of cellular tissue 155 Defect in excretion from the lungs 297 To increase excretion from bowels 307 A remedy for dropsy 349 In diseases of muscular tissue 356 Asclepias, In disease of the pleura 352 Agrimonia, In diseases of the respiratory apparatus 352 In diseases of the gastro-intestinal canal 353 In diseases of the kidneys 354 Aloes, To influence the large intestine 353 Baptisia, Deep color, purplish, brown, black 82 " sepsis 103 Saliva, viscosity of Ill Full pulse, oppressed 153 Pungent heat 165 Fetor of cynanche 199 An epidemic remedy 227 Typhoid symptoms 238 Pungent heat, sepsis. r 263 Belladonna, Dull eyes, dilated pupils 62 Dull, sodden expression of face 63 Expressionless eyes 66 Slow return of capillary circulation when pressure is made upon the skin 79 Dull, colorless eye 87 Fullness of tongue 106 Full, oppressed pulse 153 To influence the temperature. 166, 261 INDEX. 363 Feebleness of voice .174 Spasmodic cough 179 Pain in head, heavy, dull, sleepy 203 Pain dull, heavy, full, with sense of functional im- pairment 206 An epidemic remedy 227 Scarlatina 229 In convulsions... 231 To influence the skin 299 To influence the kidneys 304 To influence the circulation 317 A remedy for congestion 323 Feeble cerebral circulation 337 In the treatment of paralysis 343 In disease of the brain 351 In disease of the kidneys 354 In disease of the eye 356 Bismuth, Dragging down of corners of mouth 85 Elongated and pointed tongue 95 Eructations, pyrosis 112 Irritation of stomach 269 Excess of gastric juice 271 Intestinal dyspepsia 272 To influence the pancreas 293 In diseases of the stomach and small intestine 353 Bitter Tonics, Kelaxation of tissue 143 Defect in electricity 265 Absurdity in prescription .... 267 Want of expression 270 Intestinal atony 273 Want of appetite 277 Bryonia, Constricted tissues 65 Eight eyebrow drawn down, flushed right cheek 6Q Pain, excited circulation 69 . Deep flush of right cheek 86 Yenous obstruction 79 Sharp stroke of pulse, even vibratile current 154 To lessen the temperature 166 3()i STUDY OF DIAGNOSIS. Bryonia, Cough points at supra-sternal notch 178 Pain in right side of head, passing from before back- ward 203 Pain, with sense of oppression 205 An epidemic remedy 221, 227 Excess of temperature 260 "Wrong in combustion 261 To influence excretion from the lungs , 297 To influence excretion from the skin M ... 299 In the treatment of inflammation m 329 In diseases of the respiratory apparatus 352 In diseases of the articulations 356 Beeberina, Brownish discoloration of skin 92 Bromides, Scanty secretion of saliva - 110 In diseases of the testes .«.< , 355 To influence the lymphatic glands 356 Bromide of Ammonium, Sudden cry, with sobbing respira- tion 175 Spasmodic cough , 179 In disease oi the spinal cord 340 In the treatment of paralysis 343 In the treatment of spinal irritation. 347 In diseases of the brain , 351 Bromide of Potash, A remedy in delirium tremens 332 In spinal irritation 347 In disease of the brain 351 Carbolic Acid, Blanched appearance in inflammation 90 Dark coating of tongue 104 Fetor of putrescence 198 Camphor, In disease of the brain 351 In delirium tremens 332 Caulophyllum, In disease of the ovaries 355 Cactus, Precordial oppression 82 Irregularity of pulse, wrong of stroke 154 Cough pointing at supra-sternal notch 178 Morbid sounds from the heart 195 To influence the temperature 261 To "influence the pancreas .... 291 INDEX. 365 Oactus, To influence the skin 297 In diseases of the heart 352 Canabis Indica, In diseases of the urethra 355 In diseases of the eye « 356 Calabar Bean, To influence the eyes 356 Capsicum, Want of power in pulse 153 Cold feet 169, 263 In the treatment of delirium tremens 332 Chloroform, to relieve irritation of the sympathetic nervous system 65 Precordial oppression 82 Elongated, pointed tongue * 106 In the treatment of convulsions 340 Chloral, In the treatment of delirium tremens 332 Cathartics, Stimulant, Congestion of brain 62 Hydragogue, Effusion into brain 63 Full, broad tongue 95 Heavily loaded tongue 99 Creasote, In scarlet fever 229 Chloride of Sodium, Blueness with pallor 82 Increased secretion of saliva Ill In scarlet fever , 229 Colocynth, To influence the large intestine 353 Chlorate of Potash, Appearance of tongue 104 Increased secretion of saliva Ill Sepsis 165 Odor resembling lochial discharge 199 An epidemic remedy 227 In puerperal fever 231 Typhoid symptoms 238 Pungent heat 263 Chlorine, Odor of putrescence 198 Chlorinated Soda, In puerperal fever 231 Cod-liver Oil, Pinched, stringy tissues 144 Want of calorifacient food 169 Feebleness of voice 174 To influence the temperature 261 In defective sympathetic innervation 344 366 STUDY OF DIAGNOSIS. Chloride of Lime, As a disinfectant 198 Cider, Deep red tongue, dry t contracted, with dark sordes... 102 Collinsonia, In diseases of the larynx 352 Influences the large intestine and rectum 353 Chelidonium, Color dull and opaque 92 Dull, heavy, tensive pain, with occasional twinges, as if the part was being torn 106 Dull, leaden, yellow fur 100 Intestinal dyspepsia 273 A pancreatic medicine 292 Chamomilla, Gastric indigestion 270 Intestinal indigestion , 272 Charcoal, Excess of gastric juice 271 Columbo, Atony of stomach 270 Copper, Sallowness with a tinge of green 92 Dull, cheesy-looking fur with tinge of green .101 An epidemic remedy , 222, 223 As a restorative 274 Greenish pallor of skin 277 In Chlorosis 348 Colchicum, In disease of muscular and fibrous tissue 356 Cupping, Congestion of brain 62 Effusion into brain 63 Cypripedium, In the treatment of diseases of the brain 351 Digitalis, Fullness of the tissues of the face ,... 65 Dull, leaden color 82 Pulse, want of power in impulse 153 To influence the temperature/ 261 Frequent pulse 317 Change in the character of the pulse 318 To influence the sympathetic nervous system 344 Drosera, Spasmodic cough 179 Whooping cough 229 Measles, 229 To influence excretion from the lungs. 297 In diseases of the respiratory apparatus 352 Emetics, Heavily loaded tongue at base...., 99, 271 Erecthites, In excessive secretion from skin 299 INDEX. 367 Erigeron, Passive hemorrhage r 115 To influence secretion from the skin 299 Ergot, Fullness of eyes, face, prominent veins 62 Passive hemorrhage 115 Feeble voice, sighing respiration 174 A remedy for congestion 304 Slowness of pulse - 318 In the treatment of paralysis » 343 In disease of the spinal cord 347 To influence the uterus 355 Electricity, To influence the temperature 261 Epilobium, Intestinal irritation 272 In disease of the gastro-intestinal canal 353 Eryngium, Irritation of the bladder 322 In disease of the bladder 354 Gentian, Loss of appetite, 270 Gelseminum, Bright eyes, contracted pupils, flushed face 61 Inflammation of brain 62 Pain, with evidence of excitation 69 Restlessness, with determination of blood - 71 Vascular excitement.*., 70 Elongated and pointed tongue *. 106 Pinched, contracted tissues 142 Full pulse, vibratile ~ 153 To influence the temperature 166, 260 Sudden, shrill, sharp cry 175 Pain, sharp, restless 203 Exalted sensibility, arterial throbbing 206 An epidemic remedy 227 To influence the skin 299 In jaundice * 290 In irritation of the kidneys- 304 Frequent pulse 317 In the treatment of delirium 331 " mania , 333 '* convulsions .,o 340 paralysis 34? " delirium tremens 332 368 STUDY OF DIAGNOSIS. Gelseminum, Determination of blood 322 In hyperemia of the spinal cord , 339 In suppression of urine 341 To influence the sympathetic 347 Gallic Acid, Passive hemorrhage 115 Helonias, Pinkish color of surface 86 Hydrastis, Yellow coating of tongue 100 Intestinal dyspepsia Ill Eructations feebly acid 112 Indigestion 269 Tongue full and expressionless 270 In disease of the stomach 353 In delirium tremens 332 Hamamelis, Swollen, relaxed eyelids 84 Color purplish from venous stasis 89 In diseases of the large intestine 353 " urinary apparatus 354 " venous system 355 Hydrangea, In diseases of the bladder 344 Hypophosphites, Pinkish color of surface 86 Dull, leaden color of tongue 103 Tissues loose and flaccid 143 Feebleness of voice. 1 74 To influence the temperature 261 Hydrocyanic Acid, Elongated and pointed tongue, reddened tip and edges 95 Acid eructations 112 Gastro-intestinal irritation 269 In diseases of the gatro-intestinal canal 353 Iodides, Scanty secretion of saliva 110 Iodide of Ammonium, Tissues pinched and contracted 144 Localized pain 206 Iodide of Potassium, Fullness without elasticity 143 Not when tissues are pinched or stringy 144 Iodine, As a disinfectant 198 To influence the pancreas. 292 In the treatment of delirium tremens 332 A stimulant to the sympathetic 347 INDEX. 369 Iodine, To influence the lymphatic system 356 Iron, Muriate of, To influence the skin 300 In the treatment of inflammation 329 Solid blue color 82 Eyelids full, swollen 84 Blueness of veins . 87 Tissues loose and flaccid 143 Feebleness of voice 174 Pain in the back of head, dull, heavy 203 An epidemic remedy 222, 223 In zymotic disease 231 An endemic remedy 239 Defect in electricity 265 As a restorative 273 Want of color.. 274 Anaemia 310 Anaemia of the spinal cord 339 Deficient sympathetic innervation 344 In chlorosis 348 In wrongs of the venous circulation 355 Muriated Tincture, Blueness with deep color of tongue 87 " " Deep erysipelatous redness 90 Iris, Scanty secretion of SaMva 110 Enlarged thyroid gland In disease of the lymphatic system 356 Ipecac, Excess of color 79 White line around mouth with thinning of tissue 84 Elongated and pointed tongue 95 Acid eructations 112 Opaque mucus 114 Active hemorrhage 115 To relieve irritation of stomach 269 Pinched face . ..... 272 To influence the pancreas 293 To influence the skin 299 Irritation of the bowels 322 In disease of the respiratory apparatus 352 In disease of the ^astro-intestinal canal 353 370 STUDY OF DIAGNOSIS. Lobelia, General bluish or purplish color from venous ob- struction 89 Fullness of eyes and face 62 Want of sympathetic innervation 65 Capillary stasis from venous obstruction 79 Precordial oppression and constriction of the chest... 82 Fullness of tongue 106 Full and doughy tissues 142 Pulse full and doughy , 153, 155 Halting voice 174 Oppressed voice 175 Yielding or tremulous character of sounds from the chest 189 Anguish, fear of impending danger 204 An epidemic remedy 1 227 In measles 2*29 To influence the temperature 260 Defective excretion from the lungs 297 To influence the skin 299 To influence the circulation 317 Slowness of pulse 318 Congestion 323 In disease of the respiratory apparatus 352 In the treatment of convulsions 340 Lime, As a restorative 273 In disease of cellular tissue 275, 356 In lesions of nutrition 314 Lycopus, To influence the temperature 261 " " " respiratory function 297 " " " skin ., 299 Macrotys, Pain from an excited circulation 69 Deep color under the eyes 84 Contraction and irritability with pain 142 Steady vibratile pulse without wave 154 With Khus 205 Continued succession of tensive pains 203 In determination of blood to the uterus 322 In the treatment of inflammation 32? INDEX. 371 Macrotys, In diseases of the reproductive apparatus 355 In diseases of muscular and fibrous tissues 356 Nux Vomica, Illustrating the action of medicine. 15 Full, expressionless eyes and face 65 Expressionless mouth 67 Pain with enfeebled circulation 69 Unsteady movement, anxious countenance 72 Brownish-yellow coloration , 92 Yellow coating of tongue... 100 Fullness of tongue, 106 Increased secretion of saliva.. Ill Influences the temperature 166 Pain pointing at umbilicus 203, 205 An epidemic remedy 227 Defect of electricity 265 Atony of stomach.. 270 Atony of intestine 273 To influence the pancreas 292 To influence excretion from the lungs 297 In congestion 323 In the treatment of delirium tremens 332 To influence the brain 337 To influence the spinal cord 338 In anaemia of the spinal cord 339, 347 In the treatment of convulsions 341 In the treatment of paralysis 343 In diseases of the brain 351 In diseases of the gastro-intestinal canal 353 Nitric Acid, (See Acids,) Violet color 82, 103 Nitrate of Soda, An epidemic remedy 222, 223 Opium, Pain with evidence of atony 69 Moisture of tongue.... 105 Small pulse, open, square wave. 153 Pulse soft and open ■. 154 In delirium tremens 332 To influence the brain 351 Oxide of zinc, Gastric irritation 269 A pancreatic remedy... 292 372 STUDY OF DIAGNOSIS. Panax, Scanty secretion of saliva 110 To influence the pancreas , 292 Peach bark, Amygdalus, elongated and pointed tongue, red- dened tip and edges 95 Irritation of stomach , 269, 270 Intestinal irritation 272 To improve digestion 293 Permanganate of Potash, Erysipelatous redness, blanched... 90 Cadaverous fetor , 198 Phosphorus, Full, pallid face, waving alae nasi 65 Unsteady movement 71 Eyelids full, swollen, expressionless 84 Pinkish color 86 Dull and opaque skin 93 Dull, leaden color of tongue . 1C3 Moist mouth Ill Feebleness of voice 174 To influence the temperature 261 Deficient electricity 265 As a restorative 273 "Want of expression 274 To influence excretion from the lungs.... 297 Anaemia 310 Bad blood 314 To influence sympathetic innervation 344 In disease of the brain 351 In disease of the respiratory apparatus..... 352 In disease of the urinary and reproductive organs 354 In diseases of the skin. 356 Phosphate of Soda, Secretions of the mouth neutral or acid.. 112 Phosphoric Acid, Tissues pinched and stringy 143 Potash, As a restorative 273 Pallor of mucous membranes, impairment of muscular power 276 In anaemia 1 310 Bad blood 314 In the treatment of scorbutis 349 In disease of muscular tissue 356 INDEX. 373 Polygonum, To influence excretion by the skin 299 Phytolacca, Scanty saliva....... 110 Pulse, dull stroke with tremulous wave 154 Mammary inflammation 330 In diseases of the mouth and salivary glands 353 In disease of the testes 355 In disease of muscular tissue 356 Pepsine, Enfeebled digestion 272 In disease of the stomach..., 353 Podophyllin, Illustrating the action of medicine 15 Fullness of the tissues of the face 65 Cellular tissue full, veins prominent 6Q Full upper lip, pallor 67 Yenous obstruction 79 Fullness of tissue 84 Change in pigment, liver spots 92 Yellow coat of tongue 100 Fullness of tongue 106 Moist mouth Ill Full, open pulse 153 Contra-indicated when pulse is small and wiry 154 Pain in ischiatic notches 203 An epidemic remedy 221, 227 An endemic remedy 239 Dull, expressionless face 270 Deficiency of gastric juice 271 Intestinal atony 273 To influence the pancreas 292 To increase intestinal secretion 293 To increase excretion by the bowels 307 In diseases of the gastro-intestinal canal 353 Pulsatilla, Color dull purple 82 Eyes sunken, contracted 84 Sudden dropping of wave of blood as it passes the linger 154 Cough points at supra-sternal notch 178 Mental rest 195 Pain, sharp, limited in location, despondent....... ...... 203 374 STUDY OF DIAGNOSIS. Pulsatilla, To influence the sympathetic nervous system 344 To influence the brain 351 To influence the heart 352 In dysphagia ....... 353 To influence the reproductive organs... 354, 355 Quinine, Full, expressionless face C5 Drooping tissues, expression sad ,.... 69 Unsteady movement, relaxation of muscles 72 Causes dryness of tongue 105 Moist mouth Ill Tissues loose and flaccid 143 Soft pulse 153 Contra-indicated by hard and wiry pulse 154 Feebleness of voice...... , 174 Tremulous sounds from chest 189 An epidemic remedy 227 Periodicity 235, 236, 237 Malaria 246 A. nervous stimulant .\... 265 To influence the brain 331, 351 In delirium tremens 332 As a remedy for pain ; 337 To influence the spinal cord 339 Rhubarb, Elongated and pointed tongue, gastric irritation... 95 Acid eructations 112 Irritation of gastro-intestinal canal 269 Restoratives, Want of expression 54 To increase the blood 273 Rest, Expression of 54 Rhus, Constriction about temples and eyes 65 Pinched eyes 66 Pain with excitement of circulation 69 Bright flush of left cheek 85 Bright redness of surface 90 Eroded appearance of anterior papillae of the tongue, 107 To influence the temperature 166 Sharp cry, cry encephalique 175 Frontal pain, pain in left orbit 203 INDEX. 375 Rhus, Burning pain 205 An epidemic remedy 221 Zymosis 231 An endemic remedy 239 Illustrating prescription from single symptoms 255 To influence the temperature 260, 261 Pungent heat .. ... 263 To influence the skin 300 In the treatment of inflammation 329 " delirium 331 " spinal irritation 347 To influence the "brain 351 In diseases of the heart 352 " eye 356 Santonine, White line around the mouth with fullness of tissues o.... 84 Sighing respiration 174 Full upper lip, picking at the nose 67 Staphysagria, Full, swollen eyelids 84 In disease of the reproductive apparatus 354 Senega, To influence excretion by the skin 299 Strychnia, Sighing respiration 174 Fullness of tongue , 106 Atony of gastro-intcstinal canal 270 To influence the spinal cord 338, 339 Serpentaria, to influence excretion by the skin 299 Stramonium, Constrictive pain, muscular contraction 206 Sticta, To influence excretion by the lungs 297 In diseases of muscular and fibrous tissues 356 Sulphur, Want of pigment, change of color 93 Moist, dirty tongue Ill As an antiseptic or disinfectant 198 To influence the temperature 261 Change of pigment..... 276 In hyperemia of the spinal cord 339 To influence sympathetic innervation. , 344 In disease of the liver 353 " skin 356 376 STUDY OF DIAGNOSIS. Solanum, Congestion of the kidneys 304 Sinapis Alba, Atony of stomach 270 Sulphite of Soda. Erysipelatous redness 90 Pallor of tongue, with dirty coat 83 Dirty tongue 104 Viscidity of saliva Ill Large, empty pulse 153 To influence the temperature . 165 Mawkish or sweetish odor 199 An epidemic remedy 227 Zymosis 231 Typhoid symptoms , 238 Heavily coated tongue , 271 Sulphurous Acid, (see Acid Sulphurous.) Sulphite of Magnesia, Dirty tongue, redness natural 104 Sedatives, Dryness of tongue 105 Silica, Dullness of epithelium, desquamation 276 Soda, An epidemic remedy 227 Asa restorative 275 Anaemia 310 Bad blood 314 Trifolium Pratense, Paroxysmal, spasmodic cough 230 Veratrum, Inflammation of brain « 62 In disease of atony 65 Color, simple excess of. 78 In disease of thoracic organs 79 Bright redness, arterial throbbing 90 Elongated and pointed tongue, evidencing vascular excitement in the brain 106 Glairy, tenacious mucus 113 Active hemorrhage 115 Or Aconite 142 Tissues pinched and stringy , 144 Pull pulse, with strength 152 Influence of large dose 163 Cough 178 An epidemic remedy 22 7 Zymosis 231 INDEX. 377 Veratrum, An endemic remedy 239 To influence the temperature 261 A pancreatic medicine 292 To increase excretion from the lungs 296, 297 To influence excretion by the skin 299 Frequency of pulse 317 In determination of blood * 322 A remedy for inflammation 328 In the treatment of delirium tremens 332 Hyperemia of the spinal cord 339 In the treatment of convulsions 340 spinal irritation 347 In diseases of the respiratory apparatus 352 Wet Sheet Pack, In simple increase of temperature 167 32 INDEX Abdomen, pain in 69 Acids as remedies 81 Adventitious sounds .....193 ^Egophony 192 Anatomy applied 19 Animals, Study of 50 Anaemia 310 Applied anatomy 19 Apoplectic condition of brain 62 Appearance sickly 76 Arteries 355 Articulations 356 Areola 83 Atrophic irritation 63 Auscultation 184 Stethoscope 184 Healthy sounds in chest.185 Study in English 186 Physics of 186 Morbid sounds 186 Blowing sounds 187 Blowing and moist 188 Tremulous sound 189 Sounds from cavities 190 Small 190 Dry 190 Crepitant sounds 191 Broncophony 192 ^Egophony • 192 Pectoriloquy 192 Of the heart .193 Adventitious sounds 193 Of the foetal heart 195 Bath in temperature 167 Basis for all schools 256 Blood, condition of the 66 Color from the 77 Blueness of..... 82, 115, 308 Pulse waves 149 Wave, length of. 150 Circulation of the 244 Condition of the 244 Making 273 Excess of. 308 Defect 310 Bad 311 Evidences of.. 313 Sepsis of 312 Exudates from 312 Circulation of 315 Irregular distribution of318 Determination of 320 Evidences of determina- tion of 321 Examination of 112 Black vomit 113 Blowing sounds 187 Bladder 354 Boquet 45 Books, advantage of 23 Bowels 135 Body thermometer 1 56 Bowels, liver, percussion of..l83 Excretion from the 306 Bones 356 Brain, condition of the 61 INDEX. 379 Brain, Congestion 61 Determination of blood.. 61 Apoplectic condition 62 Inflammation 62 Effusion 63 Nutrition 63 Softening 63 Atrophic irritation 63 Functional activity 64 Innervation from.. 250, 330 Pain, condition of.. .337, 351 Brown color 91 Broad and full tongue 95 Broad and pallid tongue 101 Brown and black fur 104 Broncophony 192 Cadaverous faeces 138 Capsules, Supra-renal 354 Cardiac wrongs, Color from. 89 Cavities, Sounds from 190 Certainty 24 Cerebro-spinal meningitis... 232 Cells, Secreting 283 Cerumen 295 Cellular tissues 356 Children, Better diagnosis with 30 Childbirth, Expression in 59 Change of form of tongue... 94 Cheesy sputa 114 Changes of kind of tempera- ture 170 Chest, Healthy sounds from. .185 Chronic disease, Epidemic influence in 223 Change of type in disease 224 Chicken-pox, Varicella 229 Cholera 232 Character of normal secre- tion from skin... 301 Changes in the character of the pulse 318 Chlorosis .>348 Clay-colored faeces 137 Clinical examination urine...l30 Cleanliness 197 Classification, general... 21 7, 220 Classification, nosological.... 348 Condition of the sympa- thetics 65 Condition of the blood QG Convulsions, symptoms of... 74 Color of the surface 75 From the blood 77 Of health 77 Of mucous membranes.. 77 Pigment of health 77 Transparency and clear- ness 78 Excess of 78 Capillary circulation.... 79 Eftacement of. 79 Venous obstruction 79 Defectof 80 Deepening of 80 Dark red 80 Typhoid 80 Unyielding 81 An evidence of sepsis... 80 Deep redness 81 Acids as remedies 81 Dull purple 81 Blueness 82 Violet 82 Deep purplish brown... 82 Muddy... 82 Local 83 Of the areola of the nipple 83 Under the eyes 83 Of conjunctiva". 87 Of bright red 87 Of deep red 88 Of purplish 88 From cardiac wrong 89 Erysipelatous redness... 89 Pigment 90 " Excess 90 " Transparent.... 90 " Local excess.... 91 " Deep 91 " Brown 91 u Greenish yellowyi " Dull & opaque. 92 " Bright yellow.. 92 380 STUDY OF DIAGNOSIS. Color, pigment, greenish 92 " Tallow-like 92 " Dirty 93 " Want of 93 Of faeces 137 Coatings of tongue 97 Yellow 100 Dark 104 Contraction of tongue 106 Cough 176 Expresses irritation 176 Dry, ringing 177 Forcible ■. 177 Strength 177 Short, sharp, hacking... 178 Points 178 Spasmodic 179 Contagious diseases 227 Condition of the blood .245 Of the tissues 278 Of the kidneys 303 Constipation 137, 306 Congestion 61, 320 Evidence of. 321 Convulsions 339 Intrinsic 340 Extrinsic 341 Cord, spinal 351 Cry of pain 43 Encephalique .175 Cu'tivation of the senses 38 Dark red color 80 Dark coatings .104 Dark brown faeces 137 Dead, awake, asleep 25 Development of senses by use.. 34 Decumbence 53 Depression or excitation 55 Determination, expression of 69 Defeneration, expression of.. 70 Defect of color 80 Deepening of color 80 Deep redness, associated with asthenia 81 Deep purplish brown 82 Deep color 91 Dessicated mucus ,114 Deposits, urinary.. 129 Table of urinary 134 Deficient fieees 136 Deposits 279 Degeneration 280 Defect in secretion 299 In excretion from lungs,297 Of the blood 310 Determination of blood 320 Delirium 331 Delirium tremens 331 Diagnosis, study of 9 Anatomy necessary in ... 20 Methods of 28 Better with children 30 Use of the senses in 48 By the eye 49 By the touch 139 By the ear 171 Physical 179 Disease not an entity 12 Expressions of.....* 14 .Relation between reme- dies and 15 Varieties of color in 42 Evidence of local 58 Local 66 Range of temperature inl59 Temperature in chronic 160 Cause of. 165 Voice expresses 173 Laryngeal, voice changed by 176 Diseases, classification of. 21 1 Contagious... 227 Change of type in 224 Disuse, senses lost by 35 Dirty color 93 Dirty fur 103 Discharges, examination of.. 108 Disinfection 198 Distinction and definition of disease 209 Digestion, intestinal 272 Distribution of blood irreg- ular 7..318 Diabetes 349 INDEX. 381 Doctrine of Kademacher 222 Dryness of tongue 105 D;y, ringing cough 177 Dropsy 349 Dull purple color 81 Dull and opaque color 92 Dull, elastic stroke of pulse.. 150 Dullness on percussion 181 Ear 356 Education of the senses 32 Educated nose 45, 196 Effusion 63 Effort for rest 71 Effacement of color... 79 Elongated & pointed tongue 95, 106 Elements of disease, first 13 Empty pulse 151 Emotion 334 Entity, disease not an 12 Encephaliquc cry 175 English, study of ausculta- tion in 186 Equalizing the circulation. ..319 Errors from nosology 9 Eructations, examination of.112 Expression of the mouth 67 Provokes function 68 Of disease 14 In the Horse , 51 Law of. 57 In the face 58 In Childbirth 58 Facial 60 Of determination 69 In motion 70 Of degeneration 70 Of the voice 172 Expresses disease 173 Examination of tongue 93 Of the discharges. ....... .108 Discharges from nose.... 109 Discharges from mouth..H0 Saliva increased 110 Saliva, reaction of Ill Of discharges from the stomach , 112 Examination of blood 112 Eructations 112 Vomiting 112 Black Vomit 113 Of discharges from res- piratory tract 113 Mucus, thin, glairy 113 Mucus opaque 113 Globular sputa 114 Cheesy sputa 114 Dessicated mucus .14 Pus 114 Blood 115 Mucus streaked with blood 115 Exudative material 116 Of the .urine 116 Objects of. 118 Clinical of urine 130 Of thesediment 132 Of the feces...... 135 Care in 202 Of the urine 301 Excess of the urine 304 Of the excretions from the bowels 306 Of blood 308 Of color pigment 90 Of color pigment local.. 91 In secretion from skin... 298 Exaggeration by the sick.... 29 liy the nurse 29 Excitation or depression 55 Extension, flexion 73 Excretions, odor of. 199 From lungs, defect in. ..297 From the bowels 306 From bowels, excess of.. 306 Perversion of the 307 Exudates from blood 312 Extrinsic convulsions 341 Evidence of local disease 58 Determination of blood.321 Of congesiion.. 321 Of baof blood... 313 Eye 3^6 Diagnosis by the 49 Color under the 83 382 STUDY OF DIAGNOSIS. Facial expression 60 Favoring the affected part... 72 Faeces, examination of 135 Increase of 136 Fluid 136 Deficient 136 Color of 137 Dark brown 137 Greenish 137 Clay-colored 137 Fetor of 138 Cadaverous.... 138 Odor of. 200 Feebleness of voice 174 Foetal heart, auscultation of. 195 First elements of disease... 13 Fivesenses 36 Fissured tongue 95 Flexion, extension 73 Fluid, dullness from 182 Forcible cough 147 Form, recognition of 42 Frequenc}^ of pulse 146 Increased 316 Functional activity of brain. 64 Function, expression pro- vokes 68 Full and broad tongue 95 Fur, dirty tongue 103 Fullness of tongue 106 Full, systolic wave of pulse. 151 Full pulse 151 Gangrene 327 Glyiry, thin mucus 113 Globular sputa 114 Glands, intestinal...... 292 Greenish yellow color 92 Grayish or yellowish fur 107 Gravity, specific 119 Greenish faeces 137 Growths 281 Hardness of pulse 151 Hard, small pulse 151 Halting voice 174 Hacking, short, sharp cough. 178 Hearing 42 Health, color of pigment in. 77 Hemorrhage 127 Healthy standard of temper- ature 155 Health, range of tempera- ture in 158 Healthy sounds in chest 185 Heart, auscultation of the.... 193 Foetal, auscultation of... 195 Heat from inflammation 325 Hemiplegia 342 Heart 352 I Huxley, method of 22 Imagination 30 Irritation, atrophic 63 ; Irritation 322 \ Indications for quinine 154 I Inflammation and fever,tem- peraturein 161 J Influence of sedatives 163 j Increased frequency of pulse316 | Inter-wave current-pulse.... 151 Inflammation 62, 323 Symptoms of .....324 liesolution of 324 Pain from 325 Heat from 325 Swelling from 325 Kedn ess from 326 Wrong of function from326 Danger to the life from. 326 Innervation * 330 From the brain 330 Insanity 333 Intrinsic convulsions 340 Innervation, sympathetic. ...343 Intestine, small 353 Large 353 Intestinal digestion 272 Glands 292 Irregular temperature 169 Distribution of blood. ...318 Irritation, spinal 344 Kidneys, condition of... 303, 354 Knowledge, source of 17 Senses the source of 32 INDEX. 383 Law of expression 57 Larynx 352 Large intestine. ., 353 Lesions of nutrition 314 Life, one 12 Wrong 12 Stud}- of 13, 16, 17 Living man, study of. 18 Light 40 Lines, white around mouth... 84 Lip, pallid upper 84 Liver, percussion of.183, 289,353 Local disease, evidence of.... 58 Diseases 66 Color 83 Bright red color 87 Excesi of color 91 Disease 51 Lungs, the 352 Defect in excretion from297 Lymphatic glands 353 Man, study of the living... 18 Mania, puerperal 332 Method of Huxley 22 Measurement 24 Methods of diagnosis 28 Mediate or direct percussion 180 Medical stinks 196 Medication, restorative 273 Metamorphosis, retrograde.. 2 79 Mouth, expression of. 67 White lines around the. 84 Bluish tint around the... 85 Salivary glands 353 Movement, rapid 71 Unsteady 71 Moistening tongue 96 Movements of tongue 107 Morbid sounds 186 Moist, blowing sounds 188 Muscles 74 Mucous membranes, color of 77 Muddy color of blood 82 Mucus, thin, glairy, opaque..H3 Dessicated 114 Streaked with blood, 1 15,293 Muscular tissue 356 Names, prescribing at 10 Nausea 67 Names necessary 214 Nipple, areola color of the... 83 Nosology 207 Errors from 9, 208 Distinction & definition. 2o9 Useless 15 Nosological classification.. 348 Nose.... 352 Educated 196 Examination of dis- charges from the 109 Nomenclature 210 Nutrition, lesions of 314 Objects of the examination... 118 Odor of the excretions 199 Of the urine 200 Seminal 200 Of fseces 200 (Esophagus 353 One body, one life 12 Opaque mucus 113 Ovaries... 355 Pain 56, 68, 203, 336 Cry of 43 From inflammation 325 The result of two condi- tions 69 In the abdomen 69 Pallid upper lip 84 Pallid and broad tongue 101 Palpation 183 Patient, information from. ..200 Pancreas.. 291 Paralysis 342 Paraplegia 343 Percussion 179 Direct or mediate 180 Rules for 180 Object of... 180 Standard of comparison. 181 Normal resonance 181 Increased resonance 181 Dullness 181 Dullness from fluid 182 384 STUDY OF DIAGNOSIS. Percussion on other parts... 182 Over liver and bowels... 183 Pectoriloqy 192 Perversion of secretion 300 Of urine 304 Of the excretions from the bowels 307 Peritoneum.. 354 Physical diagnosis 179 Physiology applied 22 The basis of practice 27 Physiological standard 24 Table 215 Physics of auscultation 186 Pharynx 352 Pigment color of health... 77, 90 Pinched & shrunken tongue. 95 Pleura , 352 Polypharmacy 11 Position to remove pressure. 59 Pointed, elongated tongue... 95, 106 Prescribing at names 10 Prostate gland ■. 354 Purple dull color 81 Purplish 82 Color, local 88 Pus 114 Puerperal mania 332 Pulse, the.., 144 Anal}-sis of 145 Frequenc}' of 146 Respiratory association 147 Relation of temperature to 148 Blood waves .149 Volume 149 Sharp impulse 150 Dull, elastic stroke 150 Length of blood wave... 150 Oppressed 150 Surface of wave ....150 Shock wave 150 Full, systolic wave 150 Inter-wave current 151 Full 151 Hardness 151 Small, hard 151 Pulse, small, soft 15\ Small, vibratile 151 Empty ....151 Remedies indicated by ...152 Indications for quinine..!54 Relation to touch 155 Relation to temperature. 160 Increased frequency of..316 Slowness of. 317 Changes in the charac- ter of 318 Pyaemia 349 Quantity of urine 119 Quinine, indications for 154 Rapid movement 71 Range of temperature in health 158 In disease 159 Recognition by touch 21 Of form 42 Rest and unrest 54 Eftbrt for 71 Resonance normal 181 Increased 181 Red, dark color 80 Bright color, local........ 87 Deep color, local 88 Redness, erysipelatous color, 89 Tip and edges of tongue, 101 Red, deep tongue, 102 Reactions of saliva. ...... .....Ill Respiration, association of pulse 147 Remedies indicated by pulse, 152 Relation to touch by pulse... 155 Registering thermometer.... 157 Relations of pulse and tem- perature 148, 160 Restorative medication 273 Retrograde metamorphosis..279 Recrementitious secretion ... 286 Resolution of inflammation..324 Saliva, increased 110 Salivary glands 353 Scanty urine 302 INDEX. 385 Scor'butis 348 Senses, education of 32 The source of knowledge, 32 Acquired 33 Developed by use 34 Lost by disuse , 35 Conscious life thro' the... 36 Five 36 Cultivation of the 38 Use of in diagnosis 48 Sediment of urine, examina- tion of 132 Seminal odor 200 Secretion.. 282 Secreting cells 283 Secretions, recrementitious...286 Sebaceous ,294 Excrementitious 296 Defect in 299 Perversion of 300 From the skin, excess in, 298 Sepsis of blood 312 Sensibility 335 Shrunken, pinched tongue... 95 Sharp pulse 150 Shock wave 150 Sharpness of voice 175 Shrillness of voice 175 Short, sharp hacking cough, 177 Sick, exaggeration by the.... 29 Sickly appearance 76 Skin, regulating temperature by ,166,356 Slick tongue 103 Slowness of pulse 317 Smell 44 Small tongue, full in centre, 106 Hard pulse 151 Soft pulse. 151 Smell, diagnosis by 195 Small intestines 353 Source of knowledge 17 Softening of the brain 63 Sobbing respiration 175 Sounds, healthy in chest 185 Morbid 186 Blowing 187 Blowing and moist 188 Sounds, tremulous 189 From cavities 190 Small, blowing 190 Crepitant 191 Adventitious. 193 Sputa, globular 114 Cheesy 114 Specific gravity 119 Spasmodic cough 179 Spanaemia 311 Spinal innervation 338, 344 Cord 351 Spleen 354 Study of diagnosis 9 Of life 13, 16, 17 Of the living man 18 Of animals , 50 Objects of 52 Standard, physiological 24 Stomach, examination of discharges from 112 Stroke, dull, elastic of pulse.150 Strength of voice 173 Of cough 177 Standard of comparison 181 Stethoscope 184 Study of auscultation in English 186 Stinks, medical 196 Stomach 353 Surgeon, education of 17 Surface, color of 75 Of pulse wave 150 Suppuration 327 Swelling from inflammation, 325 Sympathetic, condition of... 65 Symptoms of convulsions... 74 Systolic wave, pulse full 151 Symptoms of inflammation. .323 Sympathetic innervation.. ..343 Taste 46 Tallow-like color of pigment, 92 Table of urinary deposits. ...134 Physiological 215 Of Dr. Williams.. 216 Temperature. 155 Healthy standard of 155 386 STUDY OF DIAGNOSIS. Temperature, range of in health 158 Kange of in disease...... 159 Relation to pulse 160 In chronic diseases 160 In fever and inflamma- tion 161 Treatment for 162 Influence of sedatives on 163 Relation to functional disease 164 A cause of disease 165 Regulation of the skin... 166 Baths in 167 Waste of tissue 167 Depression of 168 Irregular 169 Changes of kind.... 170 Tears 295 Testes 353 Thermometer, body .156 Registering 157 Use of ..158 Tissues, condition of 278 Muscular 356 Tongue, examination of the, 93 Indications from 94 Change of form 94 Elongated and pointed.. 95 Full and broad 95 Pinched, shrunken. .... 95 Fissured 95 Dryness, moisture 96 Coatings of 97 Coatings, whiteness of... 98 Coatings, transparent... 98 Heavily loaded 99 Coatings yellow 100 Redness of tip and edgeslOl Represents the blood... 10 1 Broad and pallid 101 Deep red 102 Violet colored- 103 Thick and large 103 Leaden 103 Slick 103 Dirty fur 103 Brown and black fur... 104 Tongue, dark coatings 104 Dryness of .105 Contraction of 106 Fullness of 106 Elongated and pointed..] 06 Small, full in centre 106 Grayish or yellowish fur, 107 Movements of 107 Touch, the 21, 39 Diagnosis by the 139 In obstetrics 141 Relation of pulse to 155 Tonsils 353 Transparency and clearness of color 78 Transparent color of pigment. 90 Track respiratory, examina- tion of discharges from.. 113 Tremulous sounds on auscul- tation 189 Typhoid color 80 Unrest 54 Unyielding color 81 Uncertainty of information from patient and nurse .201 Upper lip pallid 84 Urine, examination of the... 116,301 Deposits from 129 Clinical examination of, 130 Without visible deposit, 130 Examination of the sed- iment 132 Odor of 200 Scanty 302 Urinary deposits, table of... 134 Wrongs, symptoms of... 302 Urethra 355 Uroscopy 117 Useless nosology 15 Use of the senses in diagno- sis 48 Uterus 355 Variations of color in disease, 42 Vagina and vulva 355 Venous obstruction 79 INDEX. 387 Veins 355 Blueness of 86 Violet color 82 Colored tongue 103 Vibratile pulse 151 Vomiting.'. 112 Vomit, black 113 Volume of pulse 149 Volition, will 334 Voice, expression of the 172 Expresses disease 173 Strength of 173 Feebleness of 174 Of nervous irritation.... 174 Halting 174 Oppressed 174 Sharpness of 175 Encephalique 175 Shrillness of 175 Sobbing respiration 175 Want of color 93 Wave of blood 149 Blood, length of 150 Surface of 150 Shock 150 Full, systolic 151 Intercurrent 151 Waste of tissue , 167 White lines around mouth... 84 Whiteness of tongue 98 Will, volition 334 Williams Dr., table of 216 Wrong life 12 Cardiac, color from 89 Wrongs of function from in- flammation 326 Yellow, greenish color of pigment 92 Bright color of pigment 92 Coatings of tongue 100 Yellowish fur on tongue 107 H 257 83 <* r oV ^ ♦! •.T.V -hO j V ' % £ ^ •iaSfizfc ^ ,# : '**\ ^ ■><* **n ?W?* ** *« J9K* <^ ^ -:w?* ^ «s°* . .y^'"--' -.. MAR 83 N. MANCHESTER, INDIANA 46962 J* ^ niii mihiiii illinium