TUB&RCULOS OICSK CONSUMPTION f JK BY H. H. SPIERS, M. O. R. NA. OHIO, GipgtaH?.J.3l2^: COPYRIGHT DEPOSIT; TUBERCULOSIS OR CONSUMPTION. — BY — J H. H. SPIERS, M. D., I) RAVENNA, OHIO. THE LIBRA CONGRL One Copy Received FEB. 9 Cop^wwht pntpv CLASS «-XXo. Nn. ^ 7. I L> %^\ COPY 8. , COPYRIGHT I902, BY HENRY H. SPIERS, M. D. RAVENNA, OHIO. 4 To A Weak, Common and Suffering Humanity These Articles are Respectfully Dedicated Preface to First Edition. In offering these papers for 2 second reading, it is the hope they will diffuse a brighter light by a collective ren- dering. Short articles, given from time to time, on various topics, and in many journals, seldom come under the eye of one individual. Hence the necessity of unity in presen- tation. The intractable nature of tuberculosis is our only apology. Respectfully, H. H. SPIERS, M. D. Ravenna, Ohio. Preface to Third Edition Fourteen years ago the law of tuberculosis was given the Portage Count}* Medical Society, at Ravenna, Ohio. In December, 1890, it was presented to the profession at large through the Cleveland Medical Gazette. During this pe- riod of twelve or fourteen years, the writer has constantly been before the medical public, upwards of one hundred ar- ticles have issued from his pen, in current medical literature. To-day, as never before, the causation and prevention of tuberculosis is clearly recognized. In this third edition of tuberculosis the writer endeav- ors to present more clearly the manifest workings of law. In this attempt the generous patronage of an unbiased pro- fession is asked. H. H. SPIERS, M. D. Ravenna, Ohio, Jan. 31st, 1902. PRELIMINARY STATEMENT. As my view of the origin of tuberculosis is at variance with established teaching, perhaps a. simple statement of be- lief is necessary. i. Tuberculosis is a constitutional disease, dependent largely on the evils of civilization, and governed by the fol- lowing law : The death rate from tuberculosis is in direct ratio to suspension of atmospheric influence. 2. The suspension or abeyance of atmospheric influ- ence may take place from within or from without. From without through impure or impoverished atmosphere ; from within through defective lung tissue, original or acquired. 3. Abej-ance of atmospheric influence, in whatever way induced, causes a depraved tissue or dyscrasia, through which the tubercle bacilli enter and grow. 4. The growth of tubercle bacilli, being dependent on the precedent state or condition of the individual, is never ■per sc the primary cause of tuberculosis. 5. Tuberculosis may exist, though infrequent, in the absence of tubercle bacilli, but can never exist without the precedent state or condition. 6. The plant growth, being a secondary condition or modifying influence in this most fatal disease, treatment di- rected against this growth must ever remain barren of per- manent curative results and dangerous to the patient. 7. The precedent or primary condition being subject to law, and under control, tuberculosis is under control. II MEDICAL THEORIES. When a small boy there came to my hands a pamphlet, which stated' the earth is flat, like a table, and rests on four huge elephants ; each elephant stands oil four tortoise. Child-like I ask mother, what do the tortoise stand on? 1 To me the theory was highly significant, but to be complete it required a little earth filling. Many theories of the past have been shown to rest on equally unstable bases. Many theories of the present, I apprehend, will be shown equally illusory. Many questions will be asked in the same child-like simplicity, and many learned disqusitions will be given to prove that which never did exist. Such is life, and such is the history of all human progress, with its periods of per- tinacity and vacillation alternately shown. Would you then discard all theory ^ By no means. Theory answers a great purpose in the world's advancement on scientific lines. Our theories are in one sense our ideals. We search for and endeavor to establish that which we really believe to be true. Thus far, theory is laudator}'. But it is evi- dent a theory must be based on some thing more than pure imagination. is the earth flat like a table, etc.? Would it not be better to take established truth as a ground-work, and build on this? But where can established truth be found? In medicine, in theology and in law we are constantly in search of it. Oft-times truth lies close beside us and zve see J not. To-day the great medical telescope is located in Ger- many. Multitudes of people flock to hear its revelations. 12 Nothing worthy of credence, observation or regard is seen, except through this instrument. To-day it is a bacillus— To-morrow a coccus. Each day is prolific in new schemes of detecting, cap- turing and destroying microbes. A very laudable under- taking to say the least. One microbe is accused, tried and condemned and the sentence is pronounced. Another passes through the same ordeal and comes out innocent. In the fatherland, a microbic court-of-law is in session at all seasons of the year. The strangely curious thing is : That whether innocent or guilty it matters not. No mi- crobes have received capital -punishment in situ. In other words, no remedies have been found that will eliminate or destroy the microbe without causing the death of the patient. Let us look further. The savant Koch has demonstrated that in tuberculosis there is generally found a microbe at the seat of lesion. This is called the bacillus tuberculosis, for it is found in no other disease. That the microbe is present is universally ac- knowledged. They have been seen in colonies, in diseased tissue, by innumerable observers. Seeing is believing. Thanks to our distinguished contemporary. That this ba- cillus is the cause of the disease named has been received without serious question. The only serious question has been how to rid the sys- tem of the microbe. The result of treatment has been already shown. That the disease may be modified by the presence of the bacillus, I think there can ])e no serious doubt . That the microbe has any casual action in producing the disease is, in my judgment, pure speculation. Astronomers tell us that presumably the planet Mars is inhabited. If inhabited, who can say its people are not well up in the arts and sciences —possibly have telescopes. Imagine a resident of Mars engaged in the stud}- of as- tronomy. Through his telescope he views the surface of —13— the earth and sees a flock of crows hovering near the car- cass of a sheep. What are these crows doing ? Day by day he watches them closely. They are eating the sheep. At once he concludes that the sheep are being killed by the crows. A book is written. This is standard authority in Mars. But one observer sees a dead sheep on which there are no crows. Again he looks and descries another. He publishes his observations, and asserts that sheep die from other causes than crows. Is not the conclusion a valid one? Again and again observers have found bacilli in the sputum and lung tissue of phthisis pulmonalis. Observations to this effect have been published from time to time. The microbe is charged with causing the disease. This is stand- ard authority. But one observer finds a case of phthisis pul- monalis in which no bacilli can be found in the sputum or lung tissue. He publishes the results of his observations and I assert that people die of phthisis pulmonalis, in which the bacilli do not enter as a factor. Is not the conclusion a valid one ? A new observatory is now erected on the planet Mars. Its telescope is of the finest make and highest power. The observer brings his instrument to bear on the planet earth, and sees not only dead sheep and live crows in abundance, but also multitudes of little birds which he calls sparrows. He watches these little birds closely. They are engaged in a contest with the crows. " They fight fiercely. At length the sparrows are victorious and the crows are driven from the field. The astronomer concludes his writings by saying that in order to prevent the death of sheep on the earth it is only necessary to increase the number of sparrows. A few tim- idly object to this teaching, but it is standard authority in Mars. Sparrows are now plenti ful, but sheep still die. Something wrong. A new scheme is now devised to clear the earth of its dread visitant, phthisis pulmonalis. It has the sanction of high medical authority. Phthisis pulmonalis is caused by — 14— tubercle bacilli. Two methods are open to rid the system of these microbes; the direct and the indirect, analogous to our dealings with the Indians in the past. Direct, to kill him: indirect, to take him from his feeding ground. In either event the microbe or Indian must die. A few timidly ob- ject, but this is standard authority. Tuberculin is plentiful, but mankind still die of phthisis. Something wrong. Science, though slow, makes progress even in Mars. A pains-taking observer has been watching a sheep for many months. He has seen the animal die. Crows could not have killed him, for none are in that neighborhood. A brother astronomer examines the sheep and says he finds foot-prints in the earth near by — probably crow tracks. The crows killed the sheep, but were driven away by the sparrows, or fled from sonic other cause Science in Mars. Likewise in earth science is progressive. A pains- tak- ing observer has been watching a case of phthisis pulmon- alis for many months. No bacilli are found in the sputa, though many examinations for the same have been made. The patient dies. No bacilli are found in the lung tissue. A brother scientist examines the body and finds tubercular nodules in the lungs. The bacilli caused the patient's death, but were either driven away or fled Jrom some other cause Science in the earth. The second observer in Mars reasons thus: Sheep die from various causes. Crows alone do not kill sheep. Crows simply eat the flesh of sheep after the}" are dead. // is the condition of the shce-p that allows the crow to begin cat i u o\ The second observer in the earth reasons thus: Man- kind die from various causes. Tubercle bacilli alone do 4 Bot kill mankind. Tubercle bacilli simply enter the tissue- as a feeding ground. // is the condition of the system that allows the bacilli to enter. 15- LAW IN TUBERCULOSIS. In mathematics, whenever a regularity can be traced, the general proposition expressing that regularity is called a lav\ . For many years I have been led to believe that tuberculosis is obeying certain fixed law, as the planets obey law in revolving around a central sun. To the general ob- server this statement may seem chimerical. Zone. Ventilation. Death Rate. Ratio. Frigid o Perfect o . . . . Zero i Torrid 5 . . . Less perfect 5 . . . . Small 1 Temperate 10 . . Least perfect 10 ... . Great 1 The ratio between ventilation and death rate is always constant. Tuberculosis obeying law ? Apparently no order in appearance or disappearance. No regularity in mode or extent of visitation. Coming and going like the wind, or a bird of the air — all is chaos, discord and confusion. So thought the ancients of the worlds about us. But soon law is discovered; order is evolved; a system is formed and it is found that not only do the planets move, but in regular orbits and with matchless precision. Stand by the seaside and watch the incoming and outgoing tide. Note with ac- curacy the flood and ebb of waters. Without previous knowledge }~ou could assuredly say these waters move in obedience to law. A law now fairly well understood — the law of gravitation. Stand by the bedside and observe the death rate from tuberculosis. Note the accuracy the figures tally year by year: Frigid zone, o; Torrid zone, small; Temperate zo::e. great Without previous knowledge you could assuredly say these factors are essentials to the formation of lav.-. On these essentials is based the law of tuberculosis. Extend your observations to the coast line of a continent. Mark the varied difference in tidal wave in the various latitudes. Truly, you could say this law is not equally potent at all places — but observe it is, nevertheless, the same law, an 1 the difference in height of tidal wave is due to the coast line -i6— of the continent. Extend your research to prevalence of tuberculosis in the cities of the world. Mark the varied difference in places of the same latitude. Truly, you could say here is absence of law. But observe the same law pre vails, and the difference of prevalence is due to abeyance of atmospheric influence. I herewith give, from standard authors, the maximum of tide for the places named; Bay of Fundy ,75 ft. Boston 10 ft. Straits of Magellan 50 ft. Florida Reefs 2 ft. Head of Persian Gulf 36 ft, Mid-ocean 2 to 3 ft. I herewith append, from W. Halle, a partial tabic showing the prevalence of tuberculosis per ten thousand, 1889 to 1890, for cities named. Brunn 76.7 Baltimore 24.9 St. Petersburg 48.8 London .........18.4 Vienna : 54.4 Rome. 22.5 As the difference in height of tide along the sea coast does not invalidate the law of gravitation, neither does the difference in per cent of tuberculosis in the various cities invalidate the law of tuberculosis. In truth, the law in both cases is verified by the appar- ent contradiction. In dealing with the problem of the tides we find it complex and difficult. Equally complex and difficult is the problem of tuberculosis. If the tide and tuberculosis be alike based on law, they should alike be susceptible of dem- onstration, and barring preconceived opinions, should alike be worth}- of credence. As already stated., the death rate is modified by abey- ance of atmospheric influence. The stabled cow, the penned sheep, the tame rabbit, the caged monkey, lion, tiger or elephant almost invariably die of tuberculosis. Seldom*, or never, do these animals die of this disease if living in the- open air. The disease prevails much more among those whose vocations are sedentary than among those whose occupations are out of doors. The mortality in prisons has been shown to be four times as great as outside. The death rate from phthisis is estimated at fifteen per cent of the total mortality, while in prisons it is from forty to fifty per cent. Primary tubercular lesions are, in a majority of cases, connected with the respiratory organs. "There is nothing essentially destructive or necessarily fatal in tuberculosis. That in all stages it may be checked and enable the person affected to live man)- years, and die subsequently of old age or other disorders." The Rev, josiah Strong, author of "Our Country," said in ni)' presence, a number of years ago, words like these: "When a young man I was declared consumptive. Sentence of death was pronounced by able physicians, east and west. I took no medicine; ate plain food and lived wholly in the open air. Today I am the picture of health." Dr. Joseph Parish, of Philadelphia, gives a similar experience. Many, no doubt, can recall cases that have a like bear- ing. It is, therefore, seen a constant ratio exists between ventilation and death rate. As the ventilation becomes poor, the death rate increases and vice versa. The law then, as laid down in October, 1890, is simplified thus: The ratio between ventilation and death rate is always constant. In order to present this more clearly to the intellect, through .the eye, I have arranged the following table: Zone Ventilation Death Rate Ratio Frigid ......... o .• . Perfect o Zero . . . . 1 Torrid 5 Less perfect 5 Small . . . . 1 Temperate .... 10 ... „ Least perfect 10 ... . Great . . . . 1 If, then, a regularity be traced, what shall we say of law:* According to the definition, law must exist. But it has been said that confinement, with insufficient ventilation means the presence of the bacillus. Observe this. Exposure to atmosphere breathed by consumptives is not attended with danger so long as good ventilation is maintained. Observe this: 111 ventilation, whether in the private room or crowded tenement, invariably increases the death rate. Good ventilation, then, insures immunity. Ill ventilation insures death. Can this much be said of the absence or presence of the bacillus? Is tuberculosis caused by the bacillus? Before the world today it stands not proven . Look upon that field, with its depression in the center. The rains of heaven fall upon that field. The depression is filled with water and it becomes a shallow lake. Rushes, reeds and grasses, peculiar to low places, begin to grow in that lake. Did the rushes, reeds and grasses cause the de- pression? Did the rushes, reeds and grasses cause the lake? Drain the lake, the rushes, reeds and grasses disappear. But, says the objector, can we not take these rushes, reeds and grasses and make them grow on the arid mountains? Yes, we can; but how great the labor and how small the result. Yes, we can; but nature does not work in that way. Look upon that man as he walks the streets. A bad family history, a prolonged illness — the depression in that field. Grinding poverty or pampered luxury has been his lot — the rains of heaven. Bacilli begin to grow in his lungs, are found in his sputum — the rushes, reeds and grasses. Did bacilli cause that man's history or illness? Did bacilli cause poverty or luxury? Take away the con- ditions, the bacilli disappear. But, says the objector, can we not inject bacilli, or a pure culture, into the healthy tissue and cause the disease? Yes, we can; but how great the labor and how small the result. Yes, we can; but nature does not work in that way. Tuberculosis caused by the bacillus? Tuberculosis is transgression of natural law. Violation of law brings its penalty; observation of law its reward. Standing near a spot sacred to every true American, I declare tuberculosis can be controlled. Not by the injection of chemicals — not by the injection of tuberculin, but by the observation of law. —i 9 — MARRIAGE, Should an attempt be made to analyze the cause of marriage one would inquire into the nature of the desire im- planted in the human breast. No attempt is made other than to express a judgment that it is largely social. In the beginning it was said: "It is not good that man should be alone." In this later da}' one portion of scripture seems to be tacitly acknowledged. Whatever the incentive that leads to marriage, whether love, impulse or ambition, in the eyes of the law united they are. The incentive -per se may be of little import, but the union is the weal or woe of two lives and succeeding generations. Generally speaking, the incentive is of great import. Two of opposite sex meet in a car or at a party and are- enraptured one with the other — a mutual liking. In what it consists even the participants can not explain, but it leads to marriage. One part}- sees another to whom he or she is attracted with an unwonted impulse, Every opportunity is sought for an introduction. The acquaintance leads to a wooing, which ends sometimes in an unrequited love, but more often in marriage. Another desires to rise in the social or financial scale — a very laudable ambition. Who does not. if honestly at- tained? The hand and heart are sought wholly for this purpose, under the guise of a fervent love — and ends in marriage. There are also those of sordid nature whole being is wrought up with having a good time. Matrimony has joys untasted. To these joys they are allured and seek kindred natures in marriage. Some seek wedlock as an oasis in the desert of life. — 20 — It is a constant theme of conversation; little else is thought of. Any one of the opposite sex is accepted readily. These subjects marry early in life. Some look on wedlock as a snare into which the unwary are entrapped. The subject is frequently referred to, but discernment is necessary in selection. These parties are hypercritical, and marry late in life, if at all. Again, we have the intellectual devotee, whose ques- tions, imaginary and otherwise, would deny the most ardent of lovers — who, in truth, settle marital questions as do the majority of people. Then there is the philosopher, who looks on wit, beau- ty and wealth as the mere accident or incident of fortune — the externals of life. Theoretically, these people have no choice except in health and a moral nature. Practically, the number who thus marry is very small. On examination, it is seen that in marriage, as in other things, all have a motive. Whatever the motive, the result attained is the home, the foundation and true secret of all organized society. On the purity of the motive hinges the secret of connubial happiness. Let those who contemplate wedlock and desire happiness study carefully this phase of the question. It will amply repay them. But marriage is something more than the union of two parties for life; it is the offspring — it is to give to that off- spring a vigorous life. Many a man or woman is deterred from marriage from fearing its burdens and responsibilities, largely how shall we feed, clothe and educate those granted us; but how few ask the greater question, how shall we best transmit health and long life to our children? A vigorous constitution — a fortune in itself — readily secures the great obje:t c - of life. Physical weakness, however great the fortune, is doomed to doubtful victory or defeat. How much wiser the parent who transmits health than wealth ! How much wiser the state that frames laws to secure healthy citizens than the one which legislates to amass individual wealth ! How little regarded by legislators ! —21 — Marriage is union — the joining of two segments, each incomplete in itself. Children are the fruit of this union. It is as consonant with reason to say that parents beget children after their kind as trees yield fruit after their kind. Observation shows it equally true. Still further, not only are the mental and physical excellencies or defects trans- mitted, but also the virtues or vices are transmitted in ex- cellence or deject. Let us endeavor to illustrate transmit- ted defect by a few familiar examples. A married couple start in life with good health as a fortune. By arduous toil a small tract of land is bought and a house erected. Another small tract is added. Still another, and so on, until five or six hundred acres are bought and paid for. Their life has been alone. Xo SaD- bath, no company, no holiday, no rest — continual toil early and late. I said alone — not so. Eight children have been added to that family. All are in poor health. The par- ents have been so engrossed in securing a competence as to forget a law of their being. Work — so commendable in all — carried to an extreme proves a vice. This vice is transmitted in physical weak- ness. The children must ever suffer the sin of their par- ents. We see this law illustrated in the wage-earner's fam- ily. Arduous toil, long hours, low wages, high rent, meager diet, etc., are some of the ways in which labor is degraded and physical vigor in parent and child emasculated. Legislation in behalf of those thus down-trodden is de- manded. It would be beneficial to the human race. Not alone in this regard is manual labor. Intellectual work is subject to the same law and grievance. Many a brain worker in the race of life has fallen by the wayside, or in an attempt to live or secure a competence has trans- mitted feebleness to his offspring. One instance of in- tellect and application is recalled, who buried twelve chil- dren under two years of age. This law is illustrated in the drink habit of today. How often we see the imbecile, the idiot and the deformed in the family of the confirmed drunkard ! Who can say — 22 these children are not equally deformed in their moral na- ture? They certainly are. How readily we condone an obliquity in a child when we know the weakness of the par- ents. In these and kindred cases law can accomplish much but I am satisfied education can do more. Not until man- kind clearly apprehend the law of their being will they be enabled to rise above a common level, even with the aid of human statute. How inefficient the best of statutes with- out an enlightened public sentiment! Thus must it ever be 7 ' 'line upon line and precept upon precept. Tr Education pre- cursory of true liberty. Dipsomania is not alone in its work of deterioration. It is but one in a series — though perhaps the greatest that is leading us down. Tobacco, opium, chloral, etc., have their votaries and claim their victims. Vicious habit is hydra-headed, and requires the actual cautery of education and law. Future generations demand it as their life. Rapid child-bearing is confirmatory of this law. In all great efforts of nature periods of rest are required. It is seen in the field and forest. In frequent births the mother's rest is short or nil, her vital force is reduced, and the children suffer from lack of nourishment intra and extra-uterine. This is seldom seen in the typical American home. More often is seen the pale face and wasted form of the mother striving to rear an only child in luxury that she may be a devotee of fashion. This much is open. Withdraw the curtain — too often is seen a tri-annual abortion. Among a privileged few is sometimes seen the family physician. To whom shall w e attach the blame ? To the frail mother ? In the writer's judgment, nine-tenths of all abortions are procured at the instigation or request of the father. To whom the blame ? To all concerned Does such action affect a future offspring ? Yes— mentally and physically — and that in a deleterious way. It is crime in the sight of God and man. Sickness in either parent causes feeble offspring. A father who begets children during a convalescence or illness entails weakness in those children. A mother seriously ill —23— during gestation either aborts or the child shows an infirm- ity. Of course, there are exceptions, but the rule may be laid down as established, that no -party should become a -parent whose health is seriously impaired. Age in one or both parents modifies the offspring. The parents, not having reached maturity, it is of ten seen that the first or second child is feeble and subsequent children are strong. With the mother nature has hef limitation. Not so with the father. In marriages where there is dis- parity of years, care should be exercised. How often we See the old man marry the young woman ! Are the children vigorous ? That depends. Some men are young at seventy, while others are old at forty. Age alone should be no bar to offspring. To recapitulate, vice transmits defect: ( To secure a 1 Vice in Parents. Overwork, mental or physical. J Choice. J \ ! Necessity. { competence. | To obtain 1 a living. Rapid child bearing, abortion, etc. Feeble }r Off- spring, Excess or ( Drink Habit and others, vicious habit. Sickness. I Age. The question may be asked, are the male and female equals in marriage? In accountabilit}^ to God and man, in the relations of life one to the other, they are equal partners. In the transmission of excellence, defect, similarity, etc., they may be equal partners, but at times there must be in- equality. In the early months of pregnancy the child is subjected to maternal impressions. During gestation and nursing the fetus or infant is living on pabulum distinctly the mother's. One would naturally infer the disposition and dyscrasia of the child to be largely of the mother. Is the inference the observation? An intelligent mother says: "When enceinte I longingly desired to attend dances. My husband thought it not best and refused to go. My only child from his boyhood until now has a mania for danc- ing.^ Another equally intelligent says: "I am ashamed of -2 4 — ni}' daughter's actions, yet am pleased she is trying- to do better, for I know it is all my own fault. She acts just as I did in the early months of gestation." There is an inequality. At conception the father in- delibly stamps an impress, and the being passes from his control. His work is done. Not so the mother. In gesta- tion the blood of the mother is the life of the child. So also in nursing. If the blood be impoverished the life of the little one is endangered. Abortion commonly occurs. The mother having a constitutional diathesis, the father be- ing in health, the diathesis is more certainly transmitted. Reverse the conditions; the diathesis is less certainly trans- mitted. The mother then has a greater power in transmis- sion than the father. This can be clearly shown only in a limited number of diseases. Maternal heredity is stronger than paternal heredity in syphilis. The family tree in tub- erculosis inclines heavily toward the mother. The fetus in utero. may be attacked with small-pox provided the mother is the subject of the disease. It is seen that while maternal impressions may affect all children it can only be presumed that maternal exceeds paternal heredity in all disease. Yet the presumption must ever be a strong one. Heredity is more or less a factor in gout, diabetes, mellitus and insipidus. The males having the disease are in preponderance to the females. This inequality does not show the male more readily transmits the diseases named, but that he is more subject to them. In fact, it rather shows the female the greater in transmission and the lesser in subjection. In that remarkable disease, hemophilia, this principle is still more strong. The mother transmits but does not inherit the tendency to hemorrhage, or, as a Dar- win might put it, the mother is a higher type of development. To formulate: i. The maternal impressions influence offspring. 2. In all so-called constitutional or specific infectious diseases a transmission, if shown, is largely of the female. From the above we would deduce: A race or stock is most surely improved by selection of mothers. —25— I have dwelt somewhat at length on the incentive to marriage. Perhaps not wisely. In every community there are some who have great faith in human statute. If there be a beneficent change in any regard it must be by law. My view accords more to education. In a democracy, enlight- enment must precede statute. It is with this endeavor the apparently little incentive is shown. If one's inclination to a partner runs in a pretty face, amiability, wealth, etc.. how absurd to so legislate as to restrict him to poverty in feature, disposition and fortune ! But if it be clearly shown that certain actions invaria- bly produce certain results; that a life of temperance and virtue is excellent and transmits excellence; that a life of debauchery and vice is defect and transmits defect, how clear it must appear to every well-thinking man and woman that there is but one way to enoble and elevate mankind: To -practice virtue and shun vice. Virtue is the obser- vance of law, vice the violation of law — the law of our be- ing. Let us shun vice and cling to virtue in marriage. 26- HEREDITY, John Milton, in "Paradise Lost," speaks of our first parents as "the loveliest pair that ever since in love's em- braces met." Milton is given to imagery, but who can think of a being more perfect than one fresh from the Crea- tor's hand, unsullied by environment, untarnished by sin? To me the creation should not only be lovely, but perfect in every particular. Looking back through the ages, I do not see Mother Eve with husky voice or disturbed respiration; neither do I see Father Adam with bacilli or tubercular nodules in the lungs. To me the conception is a perfect creation — perfect in form and in health. We are told our parents fell from this estate. The exact nature of the sin will ever puzzle theologians, but this much is certain: Adam and Eve violated law. "Of man's first disobedience and the fruit of that forbidden tree whose mortal taste brought death into the world and all our woe with loss of Eden." Then, as now, violation of law brings its penalty, ob- servation of law its reward. Evidently, the Adam of today is not the Adam of creation. Had we a complete account of disease since creation — embracing not only literature but observation — I firmly be- lieve the record would show no tuberculosis in the early centuries. All animate creation living wholly in the open air are free from tuberculosis. Our ancestors were nomads — wan- dering from place to place in search of game or pasture, sleeping under nature's canopy — life akin to animate crea- tion. The disease, in the early centuries, must then have been unknown, for we have no evidence that nature's laws —27— have in any waj r been modified or changed. If, then, no tuberculosis lurked in the tissues of our first parents, if the disease did not exist in the early cen- turies, how does it appear that one-seventh of the present mortality is due to its inroads? A frank question, and it should receive a candid answer. Tracing the genealogy of the patriarchs from Adam to Noah, we find a longevity unparalleled in the history of mankind. During this period two things stand out in bold relief — out-door life and length of days. These great object lessons may receive various interpretations. To me only one appears satisfactory: Out-door life — a sequel to crea- tion; longevity— a sequel of out-door life. Interpret them as you ma)', length of days and out-door life ever appear together. But it may be asked, is not immorality also associated ? Yes, it is — a depravity of mankind, but not a depravity of the patriarchs. An exuberance of animal spirits — with lack of self- restraint with the multitude — a consistent life of the few. We read of the general wickedness; of one hundred and twenty years given for repentance; of the flood, with the destruction of mankind. We also read "Enoch walked with God;" "Noah was a just man and perfect in his generations." A question now arises: Does heredity modify the aver- age life? In other words, does it make aught of difference to your grand-children or mine what our lives have been, so far as heredity is concerned ? I verily believe it does; that this has been true in all ages and in manifold ways. In primitive times the workings of a law on this line can be readily seen, but not as readily detected in the present gen- eration. Methuselah, the oldest man of ante-diluvian days, was the son of Enoch, who walked with God. Shem, aside from his father the oldest man of post-diluvian days, was the son of Noah, the perfect man of God. If we carefully examine, I think histo^ will show that not only do we inherit and transmit estates financial, but — 28- intellectual, moral and physical as well. In Enoch and Noah we see illustrated a law of retribution. The children inherit, the parents transmit, a tendency to virtue, plus length of days. To formulate our view: A father shortens or extends his days by vice or virtue. He transmits to his progeny a tendency to vice or virtue, minus or plus length of days. The same may be said of the mother. One parent being vicious and one virtuous, gives parents and children an equal footing in the race of life. Both parents being vicious or virtuous, makes the law doubly sure. It follows as the world becomes virtuous, longevity is increased, and vice versa. Of course, we are speaking only of the law of hered- ity or physical descent. We hold, then, as in a vase, the treasures given us. We add or take from as virtue or vice governs us. We transmit — how often less than we receive ! By heredity is meant prenatal inheritance, that which one receives prior to birth. Tuberculosis is used in its most comprehensive sense. Heredity in tuberculosis, then, means prenatal inheritance of an intractable disease. In all ages heredity has been recognized. This child looks like his father, that child resembles her mother. Physical resemblance to the biographer is heredity to the biologist. Physical resemblance is not alone, a mentality is trans- mitted. How often we see a family of children with men- tal traits or characteristics of their parents ! Yet this does not always pertain. Perhaps no better illustration can be given thar in the world-renowned Beecher family. Edward, the scholar; Harriet, the writer; Henry Ward, the orator — children of the eminent divine. A clear case of heredity in mentality. Yet today not one representative of that great family stands an equal in intellect to any of the four named. This brings us to a truth which I wish to indelibly im- press on the mind of every one. That while physical re- semblance and mental characteristic is transmitted, it is not —29— transmitted, so to speak, in one continuous stream, as with the river; there are water-falls and rapids and meanderings, so in heredity. Let no one claim that because heredity is not shown to be continuous it is no longer heredity. Heredity flows in no such perfect channel. On the principle of deviation in heredity and selection of offspring, Darwin has the great hold on the scientific mind. On this principle of deviation and selection the florist or stockman select the prettiest or best and make advances along this line. So in the thou- sand and one things we see around us. Ever since man's thoughts have been reduced to writing, perhaps before, certain diseases have been regarded transmissible from par- ent to child. Cancer, consumption and insanity belong to this class. Here is a field for the logician. If a healthy mentality be transmitted, why not a diseased mentality? If facial expression, why not other physical condition ? If tubercu- losis be a constitutional disease — and we believe it is — why not transmit the constitutional dyscrasia ? Thus, to the logician arguing from probability, constitu- tional disease is transmitted. Careful observation confirms this probabilit3 T . Insanity has been traced through successive generations in man} 7 families. Cancer sometimes shows itself in the offspring of the first generation, but more often in the second. Children of consumptives, though the environment be changed at birth, die oj this disease among other healthy children, born of other parents. We have already shown heredity travels in no perfect channel. It is therefore seen that the proof of heredity is complete. But, sa} 7 some, tuberculosis is not a constitutional dis- ease. It is a germ disease. The writer thinks differently, but for the sake of meeting on a common ground we assume you are right. The microscope makes main- revelations. By its means —30- scrofulosis and tuberculosis are declared one and the same. This has been verified in Germany. We accept it. Scrof- ulosis is modified by transmission, not so in tuberculosis. Thus it is seen, if the latter statement be true, the diseases which are declared one and the same are not one and the same. If one and the same they would alike be modified by heredity. Let me illustrate: My friend and I are walking in the country. I exclaim, ' 'What a lovely white house !" ' 'Yes," says my friend, "but that house is also black." You don't mean that same house is both black and white at one and the same time? That is just what I mean. Well, I fail to see it. My friend replies: "Were you ever in Germany ?' ' "No sir, I never crossed the North Atlantic." Well, that explains it. Ladies and gentlemen, are you satisfied with the expla- nation ? Would it not be wiser to call things one and the same that agree in every particular ? If these diseases be one and the same, heredity in tub- erculosis is rendered stronger than probable. Let us take another step. For many } T ears it was a moot question whether living bacilli could be transmitted. It is now universally agreed they may be carried by the cir- culation to various parts of the body and through the fetal circulation to the fetus itself. Ardent bacteriologists ex- claim: "Why look for heredity ? Here are seeds of disease carried to the prenatal offspring." Please reflect one moment. Did it ever occur to you that before a plant can take root there must be a suitable soil or condition of growth? Which takes priority, the plant or the soil in which it grows? Answer that question honestly and you condemn yourself. The moment you admit a growing bacillus at birth, that moment you tacitly admit heredity in tuberculosis. Heredity in tuberculosis is all we claim. We must not stop here. Imagine before you five ladies who gives intruction in painting on canvas. Your daughter — 3 i— wishes to acquire the art. Before selecting an instructor, s uppose you put a test question to each of these teachers. You hold a fabric in your hand and ask severally the color. Listen to the answers: Red, blue, orange, violet, indigo. What ?rises in your mind? One of two things — either these ladies are deceiving you, which is improbable, or else they do not understand the business they profess. What painter could instruct in blending three to five hundred shades of color who could not distinguish a primary one? You. have a son to send to college. You call before you five leading clinicians in the state and put to each the test question: What factor is heredity in tuberculosis? Listen to the answers: Nothing, little, much, a great deal, all. What arises in your mind ? One of two things — either these teachers are deceiving you, which is improbable, or el^e they do not understand the business they profess. Who can instruct except they zt'/io know? Ladies and gentlemen, have we been teaching error in the past? Come, let us acknowledge our fault, or rise in our place and refute what is said. We have not reached the pinnacle as yet. There is another step. With heredity in tuberculosis declared and demonstrated, an herculean work must be wrought. In marriage something more than minister or justice is required. It needs: i. General enlightenment in order to select. 2. A physician's certificate by both parties prior to the marriage contract. 3. A secretary of forensic medicine, with a universal marriage law. Ladies and gentlemen of the profession, when we rise to the occasion and demand these, they will be granted. —32- THE PRECEDENT STATE. When Robert Koch announced the discovery of the tubercle bacillus, its invariable association with tuberculosis and its consequent causative influence, the medical world were ready to accept anything as a working theory. Tuber- culosis had hitherto been an intractable disease. It was argued that when we have greater light or insight into the cause or causes of the disease, then we will be more success- ful in treatment. Some few physicians had anticipated the discovery. Others could see no reasonable objection to the conclusion. Figuratively speaking, the entire medical profession took off their hats and hurrahed. Had Koch discovered the same germ in health, deter- mined its invariable association and declared the presence of the germ the consequent cause of health, he perhaps would not have awakened the enthusiasm, but the truth uttered would have been equally clear. Tubercle bacilli are ubiquitous; are found in both health and disease. Growing bacilli are found only in dis- ease. A soil must precede the .growing plant. Hence, growing bacilli imply a precedent state. What causes the precedent state ? The error of Koch is a common one. Birds are seen on the growing plants. They are the supposed cause of failure in certain crops. The birds are killed. It is then found the birds were eat- ing the enemies of the growing grain. Tubercle bacilli are looked upon as the enemies of human kind. The prof ession have been largely engaged in their destruction in toto. To the writer it seems, should the extermination prove suc- cessful, tuberculosis would still exist. One thing should be plain to every observer: Health and the tubercle bacillus do not constitute disease. Some- —33— thing more is required, viz., the precedent state. What is the precedent state ? It is the condition of the individual that allows or encourages the growth of tubercle bacilli in his system. The tubercle bacilli are present in the bodies of every animate creature. They may be in the saliva, the blood, the tissue, etc. If the person be in health, or in other words, if there be no precedent state, these germs remain, or come and go, and cause no systemic disturbance whatever. Should the person inherit or should he acquire the pre- cedent state the living tubercle bacilli at once take root and flourish, for the temperature of the body is favorable to their development and growth. When these germs are found, growing in the human body the person is said to have tub- erculosis. Should one receive or acquire the condition fav- orable to the growth of these germs, this person may be said to have the precedent state. What is the precedent state ? Incipient tuberculosis — tuberculosis in the absence of tubercle bacilli. As elsewhere stated, tuberculosis may exist, though infrequent, in the absence of tubercle bacilli, but can never exist without the precedent state. In how many ways is the precedent state commonly received? In two ways — heredity and abeyance of atmos- pheric influence. Please explain in what way one inherits the precedent state? The precedent state is most commonly inherited through a tuberculous ancestry. The same state may also be inherited if one or both parents at conception, or the mother during gestation, be suffering from suspension of atmospheric influence, either from causes original or ac- quired. This, to some, may seem strange, but must of necessity be true. It is simply the violation of law on the part of the parents the precedent state transmitted to the children. To secure a healthy offspring it is showm to be just as necessary to live right as to marry right. A premium is - 34— therefore placed upon correct living and the taking of proper persons in marriage. To render this plain, let me illustrate: A mother or father has tuberculosis at concep- tion. Perhaps it is both parents who are afflicted with the disease. The children born die of tuberculosis. This seems plain. In the above, instead of tuberculosis, place the prece- dent state. The sentence then reads: One or both parents have the precedent state at conception. What would one reasonably expect as to offspring ? They would likewise have the precedent state. With children thus born, how easy to explain results. Many obscure cases are rendered clear by this explana- tion. We cite one by Austin Flint, Sr. ( "Practice of Med- icine," 1873): "Dr. Henry E. Paine, of Dixon, 111., illusirates a con- genital tendency without the evidence of inheritance. Mr, S. is fifty-seven years of age and in good health. His wife is fifty-two and well. No progenitors have- been known to die of tuberculosis. All the children, five in number, died with this disease between 1853 and 1861; their ages respec- tively being at the time of death twenty-three, twenty-five, twenty-four, twenty-two and twenty-three." In the absence of knowledge as to the occupation, mode of living, previous history of disease, etc., of Mr. and Mrs. S., the writer has the right to assume: 1. Mr. or Mrs. S., one or both, had pneumonia prior to marriage. In common parlance, the)' were well, but each had a bronchial difficulty, or perhaps an hepatized lung. To what does this condition tend? Suspension of atmos- pheric influence — the precedent state. 2. Mr. or Mrs. S., perhaps both, were engaged in an unhealthy occupation. Mr. S. in a tow-mill or grinding on an emery wheel ten hours per da}-, constantly spitting black dust from his lungs. Mrs. S. making shirts in close quar- ters fourteen hours per da}'. In either case to what would this induce? Suspension of atmospheric influence — the CO precedent state. 3. Their manner of living was unsanitary. Mr. S. was a miser. He lived in one room and kept the door shut to save fuel. Mrs. S. was a crank and afraid of night air. She put the children to bed and covered their mouths to keep,out the cold or heat. To what would this condition of things tend ? Suspension of atmospheric influence — the precedent state. Under these circumstances the parents were well or in good health, but their progeny received the precedent state just as trul3 r as though both parents were suffering from tuberculosis. Result — the children died of tuberculosis. The result would have been the same had the parents lived in our generation. They might have indulged in present scientific fads — the injection of tuberculine to cause sloughing of diseased tissue: the placing of sterilized gauze over all apertures for ventilation to prevent the entrance of microbes, so fatal to children; or, were they familiar with present ideas in the fatherland: the securing of artificial im- munity. The writer believes that under any or all of these so-called cures or preventives the children would have died as' the}' did, of tuberculosis. It is not cure, but prevention, that will ultimately con- trol the disease — prevention, not by injection, but by con- trolling the -precedent state. But hold ! Why not assume Mr. S. had a right in- guinal hernia or Mrs. S. scarletina in infancy? The reason is obvious. Nothing is assumed that does not naturally lead to the precedent state. Does it necessarily follow that one having the prece- dent state must die of tuberculosis ? It does not necessarily follow. It must be remembered the precedent state is the first link in a great chain. If there be no first link the chain will never be formed. If the first link be present, others are readily added. In a typical case will other links be joined. That depends. For the individual it must ever be a constant battle. -36- Let us endeavor to make this clear- Mr. A. has the precedent state. The soil in his system is read}- for the seed. The tubercle bacillus, the seed, is constantly present. What is the probability ? The seed will at once take root. How best to proceed ? There are three methods; i. To get away from the germ. 2, To get away with the germ. 3. To leave the germ alone or rid one's self of the pre- cedent state. To use terms more consonant with science; ( 1) Germ exclusion; (2) germ destruction; (3) germ non- intervention, 1. Dr. W. Van der Heyden, a bacteriologist of Japan, has recently built a microbe-proof house. Its manner of structure, dimensions, etc., are known to many. We t\ ill not refer to these, Japan is young in science. Science in theory and science in practice are two things. Suppose the germs cause the disease; the house perfectly excludes the germs. It is evident the doctor cannot always remain in his house. He must be a live M. D. He must attend to business. Will he take the house with him constantly ? He has a field to cultivate. Will he kindly loan the house to his servants while at work ? He has a large manufactory in which thousands of hands are employed. Will he in- clude this establishment in his microbe-proof house? If not, why not? The doctor will find theoretical science is not practical. We now introduce another class. In this we have the intellect of our land. Says an authority; Whenever I see a case of incipient tuberculosis I exclaim: "Haste to the mountains 7? Escape for thy life !" The writer asks why so great haste. To get away from the germs. "Come, let us reason together. " Suppose you stand before two bare rocks, the one on the right hand, the other on the left. On the one rock is placed one kernel of wheat. On the other rock is placed one thousand kernels of wheat. The conditions of growth, light, heat, moisture, etc., being the same, which would germinate the sooner, the one kernel —37— or the one thousand kernels ? The writer asks any man in the land to show a difference in germination. Why do you hasten your patients to the mountains ? To escape from the germs of disease. What foolishness ! Do not germs exist in the mountains ? They are not so plentiful in the mountains. If germs cause the disease, if the condition of the system be favorable to their growth, are not a few germs all that is necessary ? If absence from germs be all that is required, please be consistent. Why not lease Dr. Heyden's microbe-proof house? The truth lies here, the mountains do benefit, but the benefit does not consist in absence of germs. It con- sists in more perfect aeration of the blood. In other words the more perfect aeration drives away the precedent state and the germs do not grow. Let this be remembered. To recapitulate: (a) Science has no practical method of germ exclusion; (b) had science such method it would be useless unless germs cause disease. 2. Germ destruction. It is true germs may be de- stroyed. There are germicides in abundance, and some of them very efficient ones. It is also true that science knows no method of total germ extinction. Had we such method it would be useless unless germs cause disease. The writer thinks the latter stands not proven in tuberculosis. 3. Germ non-intervention. This is the author's own method, and, he thinks, has the merit of being practical. ■38- WHOM TO MARRY. . So long as medical men firmly believe the germ theor3 r of tuberculosis, so long there will be no true progress in prevention and control of this disease. So soon as we grasp the idea of a precedent state or condition in the individual prior to the advent of the bacillus so soon we take the first step in prevention and control. There can be no definite action until there is clear ap- prehension. If one only cares to look he can readily see the tubercle bacilli do not grow in the normal or healthy tissue. It is always in the abnormal or unhealthy tissue they take root and flourish. Tubercle bacilli, then, differ from the ordinary parasites that infest the animal and vegetable kingdoms. Again, a recognition of heredity in tuberculosis — a per- ception that something is inherited other than an active bacillus— likewise leads to investigation that will enlighten and aid in controlling the disease. It is into a channel of this character we desire to enter at this time. We have elsewhere stated, "Abeyance of atmospheric influence, in whatever way induced, causes a depraved tis- sue or dyscrasia, through which the tubercle bacilli enter and grow." In other words, a law underlies the formation or creation of the precedent state or condition. In heredity the precedent state or condition of the off- spring is received direct by parental transmission at con- ception, or more slowly, through the mother during intra- uterine life. At conception the father's work is complete. If the father at this time have a constitutional dyscrasia, or if he be violating a law of his being so as to impair his organism, the fetus will certainly show this dyscrasia or violation at —39— birth or in after years. The same may be said of the mother. If both parents have this dyscrasiaor are violating law, the result named to the fetus is doubly certain, or, perhaps better, doubly strong. At conception the work of the mother is incomplete. During gestation, if the blood of the mother be impure or impoverished, it will certainly cause the death or deteriorate the health of the intra-uterine offspring. This statement is confirmed by every -day observation. It is therefore seen that the character of the offspring must be largely deter- mined by the health of the mother. If we are clearly understood, the precedent state or condition is found in two classes: i. Those who in any way, suspend atmospheric in- fluence. 2. The fetus or intra-uterine offspring under the con- ditions named. Or perhaps it is rendered clearer by saying the preced- ent state or condition is received in two ways: i. Suspension of atmospheric influence. 2. Heredity. While the law of formation or creation of the precedent state or condition may be active in the ancestry, it is neces- sarily inactive in the prenatal offspring, -per se ; hence a question now arises: How do you reconcile a condition induced by law and the same condition induced by heredity in which this law is held in abeyance? An illustration perhaps will render this clear. Along the ocean coast there are tides. These tides are governed by law. A prevailing wind increases or diminishes the tide at any point of the ocean shore. Heredity is a prevailing wind. Heredity may increase or diminish the death rate from tuberculosis. Eliminate all disturbing elements and there would be uniformity in tide. Eliminate disturbing elements in tub- erculosis, of which heredity is one, and there is uniformity of action in law. There is this difference: The tide may -40— never be governed; heredity is, in many instances, controlled. Having tried to make plain the conjoint action of law and heredity in tuberculosis, showing that in some instances heredity aids the action of law and in others militates against its action, let us now proceed to discuss a topic in which we all are directly or indirectly interested, viz., marriage. A certain farm writer has compared marriage to the garden of the farm—in many ways a beautiful and happy comparison. The garden, a mere patch, highly cultivated/ yields the choicest and most luscious fruits; marriage, a fraction of duration, happily consummated, yields an off- spring the joy and jewel of our lives. The garden returns according to seed, soil and degree of cultivation; marriage returns according to parents, mother and care in after years, Let there be no mistake. Nature is not mocked. As the seed, soil and cultivation, so the fruitage. In marriage so many questions are involved that it seems like complication to add other conditions to those already known. But if the future welfare of a people de- mand care in selection, it must be granted that no care is too great. From time immemorial the man has sought the woman. It is the man who "pops the question." The woman chooses in the negative — receives or rejects. Whether this order should be changed, whether the change would be ben- eficial, are questions we w T ill not discuss, but there is one thing on which the writer expresses himself, viz., every man or woman's family history should be a public record. As one in the purchase of real estate goes to the public record to examine the title, so every one should have the right to examine a record of heredity when selecting a partner for life. This may be deemed foolish, but it is a foolishness beneficial to mankind. Let me illustrate. You select a partner. Whether guided by impulse or choice in the selection, she pleases you and the union is joyous but for one thing — in a number of years, more or less, usually less, the wife dies of tubercu- losis. Yet more — the children have a history of tuber cu- —4i— losis. Perhaps this is the record of a husband. The result to him is just the same; not always so to the children. All observers agree that tuberculosis travels most read- ily through the mother. Why ? Because it is the mother who sustains the fetus during gestation. A diseased condi- tion of the mother if therefore more liable to be transmitted. Father and mother are equals in conception, unequals in gestation. As social custom gives man the province of selec- tion, observation should teach him to select wisely. As social custom prescribes woman an acceptance or rejection, she should be taught to accept or reject wisely. WHOM TO MARRY. Let no man propose to a woman who has a clear family history of tuberculosis. Let no woman readily accept a man with a clear family history of tuberculosis. While the worn an, under certain conditions, as vocation, environment, etc., ma} 7 accept a husband w T ith a hereditary taint of tuberculosis, it is best for her not to do so. Under no circumstances should one secure a wife w r ith a tubercular history. The progeny in the former case is generally free from the disease, but not always so; the progeny in the latter case are seldom or never free from the disease. Of course there are exceptions. Intermarriage of tuberculous subjects should be pre- vented by legal enactment. What more can we say ? In prevention of tub erculosis education and restraint should be the watchword. In all theorizing, practical results should be the object or aim. — 4 2- EDUCATION. We must educate. We must educate. This has been the watchword in our country since its early history. A commendable watchword. Washington, Franklin and others expressed the same in like words. Some restrict education to the acquirement of knowl- edge. It is more than this. Education has for its object the development of the powers of man. This development may be along many lines of work. It truly includes orig- inal work. People must be educated even to think. It does not follow, then, that he is best educated who has the most information in store; the largest library. Rather he is best educated who best reasons from cause to effect; who, while having the requisite knowledge to in- quire, has also the ability to. generalize. We speak thus particularly, for many think education and acquisition of knowledge are synonymous. There is a distinction and of ttimes this distinction makes the difference in mankind. _ On no topic do we more clearly require education than on the one before us. Our mental shelves are laden with acquisitions, but in the writer's judgment little education is present. False notions and ideas have become so blended and intermingled with actual knowledge that much is taught which lies in shadow-land, that cannot endure the test of time. Education should lift us through or above the shadows into the reality; open the veil before us to let the sunshine of truth enter. We must educate, but we must do so as to awaken latent thought, cultivate original re- search, and teach every man to think independently. Then education will be of value. Today there is a germ theory of tuberculosis. Truly, it is a theory. Is it anything more? We think not. Med- —43— ical works are filled with disquisitions on the tubercle bacil- lus, the so-called cause of tuberculosis; when, where and how the germ is detected; its significance when found or when not found; the procedure, if latent or growing; the way to capture, isolate and cultivate; the best microscope to look at, after or into the invader, etc., etc., etc. This is all very well so far as it goes, but it seems to the writer like superficial cultivation. We need occasion- ally a subsoiler that will strike deeper and bring up that below into the sunlight, A number of years ago an enthusiastic agent was intro- ducing a certain kind of honey bee. Among the many points of excellence of this particular bee was its size, hard- iness and qualities as a honey collector; so large no other bee would quarrel with it; so hardy the climate had no effect upon it; so great a worker it did not require feeding. He dwelt on these points with a fervid oratory. A hive of peculiar construction was then introduced. It excelled every other in that the holes or exits were so small that no enemy of the bee tribe could enter. The hive was abso- lutely safe from all invaders. At this juncture an old farmer arose and asked how so large a bee could enter so small a hole. The agent was evidently master of the situa- tion and blandly remarked this was no business of his what- ever; this is the bee's look-out. After so much talk on the tubercle bacillus, what it does and what it does not, the writer is somewhat in the position of the old farmer, and asks how the tubercle bacil- lus enters the healthy organism. The reply is equally log- ical: "This is the look-out of the tubercle bacillus." This seems the only answer ever given by the bacter- iologist. Is there no other? We think there is. The fighting qualities of the tubercle bacillus, like the Span- iards, is vastly over-rated. Each desires little to do and plenty to eat. Neither would forcefully enter a harbor for temporary or permanent rest. How, then, do the tubercle bacilli gain a footing ? By falling as a seed by the wayside and simply taking root; by eating the first food that pre- —44- sents and satisfying a natural craving or hunger. The tubercle bacillus is not seeking whom it may devour. It never goes out foraging, but is everywhere present, and wherever there is suitable soil, simply grows. It is evi- dent that a soil must precede the growing organism. Every biologist will acknowledge the accuracy of this state- ment — first the soil, next the organism and lastly the growth. Say not, then, that the tubercle bacillus is a parasite. It is not a parasite. It is a vegetable organism, taking root in a fertile soil. The soil precedes, is prepared for and nourishes the growth of the organism. What is the mission of the organism ? That of a scavenger. It takes up the old, useless and worn-out tissue that has no further virtue in the economy. When this effete tissue is wholly taken up the organism disappears. So long as this tissue forms the organism thrives. In tuberculosis an animal debris is continually present. Suspension of atmospheric influence causes the debris or worn-out tissue. Remove the suspension and you at once remove the formative process. No formative process, no tuberculosis. This information may seem strange; may not be found in standard works; yet is nevertheless true. The tubercle bacillus is not the cause of tuberculosis. There is another cause, viz., suspension of atmospheric in- fluence in whatever way induced. With this truth clearly before us and ever in mind, no fear need be entertained regarding the tubercle bacillus. It is perfectly innocent and may be so considered by all. We are living in troublous times. The outlook is brighter. I^et us gird on our armor, fight the battle with courage and take heart for the future. A crisis is upon us. Men of science have laid out the metes and bounds of knowledge in this disease. ' 'Thus far thou shalt go and no farther." Men of observation, per- haps equally wise, see no progress — rather decadence; ob- serve a weakness or inefficiency in present methods. They boldly ask why this educative empty nothingness. Men of —45— the schools who hold place, perquisite and power ask why this cadence of invective. Each in his way maintains his right — a battle for supremacy. It becomes every thinking medical man to use his in- fluence for the right, whatever may betide. Disease stalks rampant through the land. Servitude, if of value, is hon- orable. Serfdom to a theory is dishonor. In this disease the gall and bitterness of bondage are severely felt. Are we thinking men ? Let us feel the chafing of a foreign yoke no longer. What is tuberculosis ? Says one: "An infective dis- ease caused by a germ." Says another: "A systemic dis- ease caused by violation of law." One says: "No tubercu- losis without a germ of disease." Another says: "No tub- erculosis without violation of law." One holds a vegetable organism or plant growth as necessary. Another holds violation of law or ill- ventilation as necessary. No tubercle bacillus, no tuberculosis. No suspension of atmospheric influence, no tuberculosis. One tries to catch or antagonize a bacillus. Another tries to correct or modify present action of law. One could prevent disease if no tubercle bacillus. Another could prevent disease if no violation of law. One says: "Give us more time; it is a question of science." Another says: "Give us a hearing; it is a question of com- mon sense. ' ' One stands entrenched with shield and banner displayed. Another stands in the open, fearing no defeat. What medicine can be more practical than preventive medicine ? 46- FOOD PRODUCT. No factor is more conducive to trie well-being of a peo- ple than diet or food product. If we turn to history and seek those nations which have secured the most lasting re- gard or aggrandizement, we invariably find a people well fed. Per contra, should we seek the tribe or race lowest in the scale of existence, whose history — if so it may be called — lies in the unwritten legend or tradition, whose home is migratory and uncertain, we find an insufficient diet, with alternate plenty and privation. So true are these statements, that brawn and brain work most harmoniously and efficiently when food product is adequate to the animal economy; so true are these state- ments that, other circumstances being equal, given the diet for five consecutive generations f the condition of a people may be fairly determined. No better illustration can be given than in the exam- ples of Great Britain and India. Great Britain, synonym for strength, has fought with nearly every nation of the earth, and today controls a do- main on which "the sun never sets." , Great Britain, a land of liberal diet. India, synonym for weakness, vast in area, population, resources and willingness to pay taxes; vast in little else, controlled by a few thousand alien soldiers. India, a land of restricted diet. Exchange the food product for five generations, think you their relative strength would remain the same ? As with the nation, so with the individual, though less marked. Show me the man or woman whose whole life diet is scant or insufficient, and I will show you the intel- lectual or physical weakling. Bone, brain and muscle are built on food ample in quality, quantity and variety. When little Oliver Twist calls for '"more" it is no idle, childish —47— whim or folly, but is au urgent call of wronged nature. The soup is too thin, the quantity too small, and the qual- ity deficient. Are there any little children in this land of plenty who are calling for more? Examine closely before you say no. Thus far we have spoken of normal or wholesome food product. But at times a staple production fails, or is defec- tive or diseased through climatic or other causes. A people dependent on one production must then face starvation or become enervated through diet. The famine in Ireland through failure of the potato crop, or local out-breaks of ergotism through eating black rye, etc., are familiar exam- ples. Again, a food product may be defective in that it is improperly cared for. Mouldy hay or musty grain must impair the health of the animal that eats them. Over-ripe fruits, partially decayed vegetables or meats improperly kept must cause sickness to the consumer. In regard to a food product there is only one royal way — to select only the best. Of food product there is only one with which we all are perfectly familiar; only one that fulfills every indication, meets every want, and in truth is ideal — pure milk. Per- fect and familiar food as milk is, no article has been more used and misused. Today it stands eulogized and con- demned. One fact remains — -pure milk a -perj ect food. The purity of milk is affected by intrinsic or extrinsic causes. In other words, milk ma}' be changed during se- cretion or after it is withdrawn. Of the various changes that take place after milking we will not refer, but simply state that they all may be prevented for a longer or shorter period by roper sterilization. Various apparatus are on the market and perfection in this regard seems to be reached. While sterilization is thus regarded so favorably there is one thing it can not do, as will shortly appear. Of the various changes that take place at or during se- cretion we wish to speak more particularly. i. It is asserted by high medical authority that tuber- culous animals secrete milk containing bacilli. So far as - 4 8- known, no one argues their presence in the milk. Seeing is believing. 2. That by sterilization the bacilli may be killed and the resultant milk rendered a perfect food. In the judgment of the writer this statement is as near prevarication as is Bill Nye's description of a cyclone. It contains some truth, but most of it is mythical. That bacilli may be killed by sterilization or that there are cy- clones, no one denies, That tuberculous milk may be ren- dered perfect food by sterilization is as mythical as Nye's description. There are two things of which American physicians can justly feel proud — practical ideas and good common sense. Suppose during the famine in Ireland that the Americans, instead of sending a ship-load of corn, had sent a ship-load of sterilizers. Would the famine have been staid ? Suppose during an out-break of ergotism some one should suggest sterilization. My dear sir, we do not eat uncooked rye. It is ground, made into loaves, and sterilized in the oven. The* people still die. No sterilization will render a diseased grain or a partially decayed potato perfect food product. Fondness of a bargain is likewise American. Suppose I have five tons of mouldy hay. It is sterilized after the most approved German method. Is there a physician in the land who will pay a full market price for this hay ? The hay is an imperfect food before a mould fungus starts. Killing the mould fungi does not restore perfect hay, Milk secreted by a ticbercu/otis animal is a diseased product — a diseased -product before bacilli are found. Killing the bacilli by sterilization does not restore a -per- fect milk Milk is a secretion — an elaboration — of principles from the blood. If the blood be pure, the milk is pure and vice versa. It is known that nervous impressions increase, dimin- ish or vitiate the milk flow. It is known that the milk of a syphillitic is poor in quality, and should be nursed only in —49— exceptional cases. What shall we say of the milk of an animal suffering from a constitutional disease ? To the writer, it seems a fallacy is foisted unwittingly on an intelligent public. Are there any little children in this land of plenty who are calling for more ? Herein lies a secret of the fifty per cent, of mortality under five years of age. Believing this, could you conscientiously recommend condensed milk for children, gathered as it is from unknown sources? Poor as are all artificial infant foods — in that they do not contain the elements of nutrition — they are superior to commercial condensed milk, in that they do not contain the elements of disease. Some one may ask what is the chemical difference be- tween diseased and healthy milk. Some one may likewise ask what is the chemical difference between a diseased and a healthy potato. Cook them and your three-year-old child will see a difference. Use the two kinds of milk and you will perceive a difference. Have you ever said to a mother: "You must not nurse your infant. You are in ill-health. The milk is a diseased product." In the moral as well as the phj^sical world no man should find fault with present conditions unless he be able to point out a better way. If pure milk be the only perfect food, if the infant human race must live on milk, the way to obtain pure milk is the desideratum of the century. i. We must have healthy animals. 2. Animals must conform to hygiene. 3. Every precaution must be taken to keep milk pure. How shall we obtain healthy animals ? What says the New York Health Board? "Use the tuberculin test and kill all diseased ones." To the writer this seems like cross- ing the valley of Lethe on the bridge morality. The bridge — a very fine structure — stops in the ?niddle of the river . In less than five years New York will again have to adopt the scientific method. — 5o- While removing the diseased animals would it not be a higher wisdom to secure a healthy progeny by selection. Animals must conform to hygiene. It is astonishing how inconsistent we are. Mothers must be very careful of diet, etc., etc., while nursing in- fants. Cows are allowed to be crowded in filthy stan- chions, eat mouldy hay, drink stagnant Water, without air, exercise or sunlight; milked at all hours, the milk delivered twenty-four hours late, is sterilized and pronounced perfect baby food. The man who sells rotten bananas and robs you of your child is no more guilty than he who thus cares for bis cows and spreads disease and death. They should alike be held amenable to law. Kvery precaution should be taken to keep milk pure. Herein lies a field for sterilization. Look over the able articles written during recent years and you will readily glean a concensus of belief as follows: (a) Diet causes tuberculosis; (b) diet cures tuberculosis; (c) diet prevents tuberculosis; (d) the same article of food taken in the same manner acts in the three ways mentioned; viz : a, b and c, at the same time, (e) Statistics prove all this. Our ascertained facts must be renovated. There is certainly something wrong. In what does the wrong consist ? We believe it con- sists in a false conception of the nature of the disease, tuberculosis. We are taught tuberculosis is an infective disease caused by the tubercle bacillus; infective in the sense that one takes the disease from another; caused, in the sense that growing bacilli are commonly found in the disease. So long as these ideas entertain and hold there can be little true progress. To progress there must be a radical change or rather interchange of ideas. Take the common food product, butter. No article of commerce is in more common use or contains greater number of tubercle bacilli. If present views be correct every time we partake of butter we are infecting our system with tubercle bacilli or causing —51— tuberculosis. On observation it is evident: (a) That multitudes of people eat butter who do not take tuberculosis; (b) that tubercle bacilli do not take root in the health}' human organism. Hence (c) butter does not cause tuberculosis only in certain diseased conditions of the system. It follows: (a) Those having this diseased condition should not ed't butter; or (b) should eat butter free from tubercle bacilli. The question now arises, what is this diseased condi- tion of system ? How does it arise or how is it caused, and in what way may we prevent it ? On close observation it is seen only those animals allow the entrance of growing bacilli who in some way have sus- pension of atmospheric influence. If there be no suspension of atmospheric influence there can be no tuberculosis. It is then a question of suspension or non-suspension of atmospheric influence, and not a question of eating or not eating butter; not a question, -per se whether tubercle bacilli be preseut or absent in said butter. If the reasoning be correct, instead of a microscopial examination of butter to determine the presence or absence of tubercle bacilli, we should examine the family histor3 r or environment of the party eating butter. The same reasoning may be applied to milk. No greater fallacy exists than that milk causes tuber- culosis. Yet it will take years to teach the public to think otherwise, because we are so imbued with the germ theory of disease. The truth will at last prevail. Some time, sooner or later, we will know better. In the accepted way, we have spoken of diet as causing tuberculosis. Let us now refer to diet as a cure of the disease. It is observed by all clinicians that tuberculous patients recover most rapidly who have good digestion and assimilation. They w T ho can eat food and digest it, increase in flesh and put on a healthy appearance. They are certainly getting better. Per con- tra , the}' who are scant eaters, or they who have poor di- —52- gestion gradually lose in flesh and become worse. They lose in flesh from lack of nourishment and from the waste constantly going on. Herein lies the secret, if there be one, of the so-called cure. Diet of food, rich in fat, if readily assimilated, restores the waste constantly going on. Does it cure? It is' certainly an efficient aid in cure. Should the cause of the disease be steadily at work, np true cure is affected by diet. Does diet prevent tuberculosis ? That there be no mis- apprehension we refer to one or two writers as expressing a belief that it does. Is this true? "Next to a life in the open air, perhaps even more than that, the question of food is of the utmost importance in the prevention of tuberculo- sis, as well as in the treatment of the disease." — Youth's Companion, March 31. Speaking of hygienic treatment: "Of equal importance with pure air is the selection of proper food and its diges- tion and assimilation," etc. — Lancet-Clinic, Feb. 5. These writings are selected simply to show the trend of modern instruction . They express what is being taught on every hand: That proper food is equal to pure air as a pre- ventive of tuberculosis. The writer thinks not. Proper food or diet per se will never prevent tuberculosis. Pure air per se will ever pre- vent tuberculosis. Taken together there is no equality. Improper or insufficient food causes inanition. Impoverished or impure air causes tuberculosis. In inanition there may be or there may not be tuber- culosis. In tuberculosis there is always inanition. To briefly summarize: Diet does not cause, cure or prevent tuberculosis. If true, how can the action of a, b and c take place at one and the same time? If true, are tubercular statistics of value? What is tuberculosis? A constitutional disease, de- pendent largely on the evils of civilization and governed by the following law: The death rate from tuberculosis is in direct ratio to suspension of atmospheric influence. —53" THE CAUSE OF TUBERCULOSIS, United States Indian Service, Yankton Agency, Greenwood, S. D., August 24, 1898. Dear Doctor — I have read with great interest your article in the last number of the Medical Record. I have held your views for some time. I have in my experience the best illustration imaginable. I have attended the Indians both here among the Sioux and in Idaho among the Bannocks. I have known many Agency physicians and have talked with them. All agree that the older Indians say they did not have consumption among them when they lived in teepees and in the open air. But as civilization advanced among them the government has constructed log cabins and small frame houses for them, and they have given up the teepee except a short time in the hottest weather of summer. Now we have consump- tion the most prevalent disease. More than half of the deaths are from it. In examining Indian children as to their physical fitness for school it is almost the rule to find tubercular glands in the neck or some evidence in the lungs. The joints of Indians and mixed bloods are rarely attacked by tuberculois. These houses are mostly low, having one room; many are log cabins with dirt floors, sealed as tightly as possible ; the whole family living in this one room, and except in summer, cooking there on a large cook stove, heating the poorly- ventilated room to furnace heat, and after perspiring freely, going into the cold air. They are in the transition stage between savagery and civilization, mentally, morally and physically. This may account in some measure for the fearful hold this disease has on them, but I think tubercu- losis came with the house and ' 'suspension of atmospheric -54— " influence." Would it be wise to embody these thoughts, rambling, in a paper to help prove the great factor, suspension of at- mospheric influence ? I trust you may find some interest in these remarks, and I thank you for the new light your valuable paper has thrown on the subject for me. Believe, me, I am, very truly yours, Geo. F. Pope, M. D., Agency Physician. The above letter is self-explanatory. The article re- ferred to is found in the New York Medical Record of August 20, 1898, and is one of a series now numbering nearly forty. In these papers it has been the endeavor of the writer to express a continuity of thought and establish the law of tuberculosis. The law and the proof of its existence may be found in the Transactions of the Ohio State Medical Society (1893). So far as known no writer has attempted to controvert this fa ^ Its author stands its champion and advocate. To some it may seem strange that disease obeys law. Why not? Is not everything in this universe subject to law ? Why not disease ? Malaria, the writer feels assured, is governed by law. He has so expressed himself in one or two published articles. So that whatever view may be entertained as to the Plasmod- ium of this disease, please remember there is a law of malaria. Cholera, the writer has long thought, is governed by law. The visitations of this disease are no mere chance visitations. Law underlies them in every instance. So we think in every disease there will be found a law. Knowing the law, we can the more readily control the disease. Medicine of the future will be largely preventive. In the past the effort has been to find a remedy that will suc- cessfully combat the symptoms of disease. This is well. We have a multitude of such remedies. In the future it will be the desire to determine the law that governs dis- ease. This will be better, in that we can the more readily predict the time, place and extent of disease zones. Then there will be less confidence in remedies and a greater con- —55— fidence in means cf prevention. All hail this happy day ! It will surely come. Malaria is a disease whose treatment is fairly well understood. In its worst type it is not considered a dis- tinctly fatal disease. It is largely enidemic and its visita- tions are under control. Cholera belongs to other climes, and visits our land only under certain conditions and {after the lapse of years. With this disease we are not so much concerned. With tuberculosis the case is different. This disease is with us at all seasons and is extremely fatal. It takes our nearest and dearest friends, and when once its grip is felt its hold is seldom relaxed. It is a strangely fatuous disease. The patient is ever having a slight relapse, never worse, gradually improving all the time, and dies in this belief. There is another fact. No treatment is of lasting benefit. The physician calls it a bronchitis, assures a cure, receives a retainer, until he who runs may read tuberculosis. Nor is this act of the physician a mere love of gain. At first he believes what he says. He then modifies his prognosis as the disease advances. At last, for fear of com- petition, he holds his patient by mere force of will. He says in his heart: "I know you cannot be cured, but you must not be a patient of my competitor. ' ' What a shame i Tuberculosis thus advances year by year without one thought of cause or cure. Of course we are speaking of the rank and file of the profession. What shall we say of them whose title, dignity and rank but belittle the name they bear? "Miserable comforters are ye all." The classic lore still guilds the page, but blinds the intellect. When will ye be wise ? In the Medical Review, October 5, 1895, the writer recalled the words of the Psalmist: "He brought them forth also with silver and gold; and there was not one feeble person among their tribes." The estimate being variously given as from one to two millions, where could we find such a people on the face of this earth today ? Cer- tainly not among the civilized. He also recalls the statement of the classic historian, Lossing. Speaking of the Indian tribes embracing the greater portion of the north temperate zone, L,ossing says: "Physical deformity was unknown, and there were few dis- eases among them. ' ' Could tubercul osis have been present ? We think not : Prof. Osier is also referred to in the same article as saying: "No race is immune. The Indians of this conti- nent are very prone to the disease. Matthews, whose ex- perience with the native race is large, states that the dis- ease is on the increase among them. The writer asks, how is the disease on the increase among them? As they come iu contact with civilization. Listen to Osier's own words, same page (Practice of Medicine, p. 185, 1892): "The death rate in the older res- ervations, as in New York, is three times as great as in Dakota." That is, the death rate is three times as great where the Indians are in contact with civilization three times as long; or, in other words, the death rate is in a direct ratio to contact with civilization. Could any testimony be more conclusive ? Carefully read the above letter, and you have the un- asked testimony of one from the field. Is it not a satisfac- tion to know we have reasoned correctly ? Is is not a greater satisfaction to see medical men in authority endorse the same view ? Would it not be a still greater satisfaction to see the dread disease, tuberculosis, banished from our midst? It certainly would. It shall be seen, but perhaps not in our day. "The world do move." Turn back the page of history and walk with me in the streets of Ephesus. It seems but yesterday Diana, that ancient goddess, blindly ruled a queen, Around her stood the workmen and knelt the votaries at her shrine. Who dare blaspheme her name ? The workmen saw that in their craft was gain. They wildly cried, "Great is Diana, the Bphesian god!" What now remains of this once lordly queen ? Perchance a broken column proclaims the place she stood. The times have changed. We worship now around —57— another temple. It is a German mosque. The worship is as senseless as of old, the gain far greater, the maddening cry of workmen yet more deafening. Who now dare speak against this altar? Here and there a still small voice. That voice will yet be heard. Along the shores of time are wrecks of theories. Here a broken rudder, there a mast, tell plainly of a palace in the years gone by. It long has disappeared. So will it be with this. -58- THE GERM THEORY. '.'And he sat in the tent-door in the heat of the day." — Genesis 18:1 The text needs little elucidation. The one spoken of is no less a personage than the patriarch Abraham. Of all worthy historic characters none stand more prominent. Born in Ur, of the Chaldees, about thirty-nine hundred years ago, Abraham, under a providence, not his own, be- came wealthy and the head of a numerous household. We read : ' 'The Lord had blessed Abraham in all things." It is not the purpose of the writer to dwell in detail, but his was a noble character, not perfect, but worthy of emulation. Two things are obvious : Abraham dwelt in a tent, and he rested at mid-day. The climate of Chaldea is such that life in the open air was common. Plainly, yet warmly clad, they dwelt as did their fathers, in tents and booths. Life to them was sweet in simple joys, which knew no after pain. Happy we, if in our race for greater joy had recognized the pain thereafter ! Man seeks greater closer habitations ; he builds a house. In building, had he kept the ventilation as in the tent or booth, all would be well. He builds regardless of an inner air, and garners as he sows — a spurious joy in dread disease — tuberculosis. In this we recognize a father's care is greater than man's protection. This, we think, is wisdom. Abraham rested at mid-day. Some think he idly sat, while others worked. The writer does not think so. He had been working, but at mid-day, while the heat was great, sat resting in the tent. A lazy man can never rest. Some may suppose he sat and slept ; the record does not say so. "And he lift his eyes and looked and lo," etc., showing —59— plainly he was wide awake — alive to duty. Multitudes are sitting, idly dreaming of the castles in the air, while the few are slowly moving upward, step by step, the golden stair. Of this few was plain old Abraham. Let us pursue the picture : "And lo, three men stood by him, and when he saw them he ran to meet them," etc. May we not learn a lesson ? Abraham sat, and looked and saw and acted. Let us imitate his example. Perhaps to day no one thing is receiving greater atten- tion from the medical profession than the germ theory of disease. Hundreds of Abrahams are sitting in their tents. Some, I verily believe, are resting. Many, wide awake, are looking with powerful miscropes and troubled gaze. Is the theory true or false ? What is seen ? In diseased conditions certain germs or microbes at the seat of lesion. At times, one kind alone ; at others, more than one. What is seen ? Myriads of bacteria or growing plants, subsisting on diseased or worn-out tissue in frail, unhealthy patients. What is seen ? A growing vegetation in a fertile soil. This is seen on every hand. Along the shores of lakes are seen the shoals of many fishes. At times, one kind alone ; at others, more than one. What is seen ? Myriads of the finny tribe subsisting on the food there placed, or propogating species of their kind in favored places. This is seen. Abraham could have seen the same and that without a microscope. As the fish along the shore take up the food and prop- ogate their kind, so bacteria in unhealthy tissue. Do bacteria cause disease ? Another class are looking, with microscope as fair and eyes as bright. They say, in words our own, no microbe, -per se can cause disease, unless said microbe be diseased itself. Wondrous knoweldge ! My friend, good bye. How can we yet determine the sickness or health of any microbe. Let us pass on. In passing would it not be wiser to as- sert that microbes are found in the environment most favor- able to growth ? The seed is scattered everywhere. It falls — 6o- in fertile places and takes root. Growing germs are found where there is proper food ; where proper food they propo- gate their kind. Do they cause disease? Look again. "Bacteria in their growth develop toxines." If by toxines is meant vegetable poison or alkaloid ; if by develop is meant store up in their substance, this statement is true. . "These toxines are given off by the growing vegetable organism." Abraham, where art thou? This, the writer thinks, is far from the truth. He finds no such fact record- ed in nature, giving plants do not give off their alkaloids while growing. They give them up only by infusion or ex- traction. Illustration : Strychnia, morphia, atropia, are vegetable alkaloids. Do the plants give off these poisons in growing? How utterly absurd ! This the writer endeav- ored to make plain some two years ago, vide "Status of the Bacillus." In order to be clearly understood, let us make a simple experiment. Put fifty pounds of rich earth in a box. Plant poppy seed in this earth. Place under the most favorable conditions of growth — light, heat, moisture, etc. The seeds germinate, the plants soon grow and develop to maturity. How do we obtain morphia ? Is there a physician in the land unable to answer? Listen to the bacteriologist : "Plants in growing develop toxines. These toxines are given off in growth." How do bacteriologists obtain morphia ? By collection from air, earth or water? If not, why not ? Do not plants in growing give off toxines? The following bacteriological experiment is very com- mon : Into a flask containing a small amount of bouillon, put a number of living tubercle bacilli. Let them multiply for several weeks. Filter out all the bacilli and inject a lit- tle of the filtrate beneath the skin of a guinea pig. See how quickly it succumbs. This, they say, is proof positive the plants give out toxines to the fluid in growing. The writer thinks not so. A plant in growing absorbs or inhibits the soil in which it grows. If the poppies in growing take up — 6i— one ounce of soil, there is just forty-nine pounds and fifteen ounces left. If in growing they develop one ounce of opium* this one ounce is found in the plants. No where else. As the plant in the earth, so the plant in the bouillon. Have we made this plain? If so, let us take another step. One suffers from tuberculosis. Tubercle bacilli are growing in his system; How are the symptoms of the dis- ease commonly explained ? Toxines are developed by the growing organism or bacilli. These toxines are thrown off by the bacilli in growing and continually poison the patient. Reason says the proper way to treat the disease is to give a remedy that will neutralize the toxines as thrown off by the vegetable organism. The writer smiles when he thinks of such foolishness. He at the same time feels vexed that men high in authority should make statements so erroneous. What is tuberculosis? A constitutional disease depen- dent largely on the evils of civilization and governed by the following law : The death-rate from tuberculosis is in direct ratio to suspension of atmospheric influence. In other words, tuberculosis exists before the entrance of the growing bacillus ; one has symptoms of the disease before there is evidence of the growing germ. — 62 ARTIFICIAL IMMUNITY The world in many ways is growing wiser. A few centuries ago they little thought of the progress to be made in the arts and sciences ; of the methods of travel, war, commerce, etc., now in vogue. Could past generations rise and view the strides taken we think they would truly be illuminated. Medicine, like other things, has been moving. While here and there the movement is retrograde, the general trend has been ahead. Should those ancient gods or myths in medicine arise we think there are many things for them to learn. But hold ! Some boldly assert the dead already know more than the living. If true, they keep this knowl- edge to themselves. There is no reliable evidence to establish intercom- munication. We have little sympathy for thinking men who consult or worship dead medical heroes. The writer believes a "live dog is better than a dead lion." The light of these men went out in their death. It is seen only in their works — "Foot prints on the sands of time." In mathematics certain facts are so plain they need no demonstration. Illustration: The shortest distance between two points is on the straight line between them. Other facts equally plain are based on an assumption. Illustration: Two and two make four, i. e. 9 according to our system of notation. We assume one is one. If one be two, then two and two make eight. These two forms of truth we will designate as innate and assumptive. The two forms are found in medicine. There is this distinction. Innate truth is accurate under all conditions. Assumptive truth may be or may not be accurate in these same conditions. There is a wide dif- -6 3 - ference in the meaning. The one is truth, the other assumption. One who reasons and uses truth and assumption as synonyms may find fallacy in his conclusion. Have we made this plain ? We believe that 'he who claims a possible immunity from tuberculosis by the injec- tion of an alkaloid of the plant tubercle bacillus is laboring under the mistake named— taking an assumption for a truth. If the writer be correct, the reasoning is of necessity fallacious. If assumption and truth be used synonymously one has no moral right to ask acceptance of his teachings. Let us be honest. In discussion one is apt to be carried away by the heat of argument and utter things which he would not in his more sober moments. This is true in all controversy. The fire which generates steam if too strong may cause an ex- plosion. No explosion is desirable. Let honesty of pur- pose and fervency of spirit be the motto. The subject de- mands it. With one-seventh of the death rate caused by this dread disease, taken largely from a people in the prime of life and otherwise well fitted for years of usefulness, let no man stand by the death-bed of his fellow and trifle or de- ceive. Rather let us be honestly in earnest. "Tuberculosis is caused by the tubercle bacillus." What evidence have we of this ? (a) Tubercle bacilli are found in the disease tubercu- losis. A murder is committed in a certain village. A, B and one thousand others are found in this village. Is this proof positive that the one thousand and two committed the murder? Would any lawyer, judge or jury so regard it? Tubercle bacilli are found in health. Is their presence the cause of health ? (b) Tubercle bacilli are found growing in tuberculosis. Please examine this answer carefully. We desire it. Rushes are found growing in a certain pond. Do the rushes cause the pond ? Is not the pond a suitable place for -64— the rushes to grow ? In tuberculosis a diseased condition is present. The diseased condition is a suitable place for the tubercle bacilli to thrive. Being found growing in this dis- eased condition is no evidence these plants caused the con- dition named. How utterly absurd? That no one think the writer has gone daft on this subject, we herewith append the following letter: Colorado Springs, Col., October 8, 1898. Dr. H. H. Spiers: Dear Doctor: — I wish to say most positively that in what you say regarding the cause of tuberculosis, etc., "I am with you,'' and that it is only a question of time before the whole truth will be known , I have studied consump- tion now for sixteen years, both in laboratory research and in a general practice among consumptives, and I have mai^ facts to prove beyond question that the tubercle bacilli only attack a tissue prepared for it. Flies only "blow" a dead horse, as the cowboy says. Hoping to meet you some day, I am, Very sincerely, C. F. Gardner. With the above statement before us we trust no one will henceforth talk of tubercle bacilli creating a soil in a healthy subject. They do no such thing. In every case of tuber- culosis the soil is prepared before the bacilli take root and grow — prepared in one way — suspension of atmospheric influence. Hence the law of tuberculosis : The death rate from tuberculosis is in direct ratio to suspension of atmos- pheric influence. This law the writer has advocated for the past twelve years. If true, the disease tuberculosis can be controlled. (c) Tubercle bacilli or their pure cultures are injected into healthy guinea pigs. In every case these animals die of tuberculosis. This, says the germ theorist, is proof pos- itive the tubercle bacilli cause the disease. Let us examine^ Admitting the injection causes the result named, it is nec- essary to show (1) the human race is a race of guinea pigs' -6 5 - (2) the method of injection is nature's method. Neither can be shown. (d) Tuberculosis is infectious. Example: Mr. H.^ aged twenty-five, is in poor health. He marries a healthy girl. Two or three years later the husband is told by an M. D. that he has tuberculosis. Mr. H. takes but little medicine, confines himself almost wholly to the house, and the wife, who is very much attached to him, stays long in the same room and ministers to his wants. One year from his first illness he dies of tuberculosis. His wife dies of the same disease about six months later. The neighbors say, "She caught the disease from her husband." If one take the disease from another in what way is the infection conveyed? In other words, if tuberculosis be due to suspension of atmospheric influence, how can this sus- pension be conveyed to another person? Do not be too hasty in judgment. Let us hear a further recital. Mr. B., of P., aged twenty- three, marries Miss T., of K. His family history is decidedly bad. At the present writing all the family — parents, children and grand-children, nine in number — are dead. The family tree is extinct. With but one exception all die of tuberculosis. One child, I think an infant, died of diphtheria. Mrs. B., his wife, aged twei^-one, is healthy, but never robust. About two years after their marriage Mr. B. dies of tuberculosis. His wife is very attentive in his sick- ness and does everything possible for him in her power. Eighteen years have elapsed. Mrs. B. looks older, but is in as good health today as in those days of her marriage. Will any M. D. in the land assign a reason why Mrs. B. did not take the disease ? Do not be too hasty and we will recite another case. Mr. B., of E., aged twenty-two, of poor family history, imperfectly recovers from typhoid fever. Two }< r ears later he marries Miss H., of about the same age and of fair fam- ily history. They settle in the township of R., and build a new house. Two children are born of this union, the elder still living, though delicate; the younger, an infant of six -66— months, dies of tuberculosis. The father dies of the same disease about six weeks later. Mrs. B. cares for both hus- band and child during their illness. Eight years have elapsed. A month or two ago I met this lady on the streets of this village, the picture of health. Why did the second Mrs. B. escape this disease? In both cases, narrated from life, the reason is simple. Need I explain ? It is these little things which tell me the law of tuberculosis must be true. It cannot be otherwise. How did they escape ? By having perfect ventilation in the rooms occupied. There is no danger whatever of "catching' ' or contracting tuberculosis if the ventilation be perfect. Why ? Because the tubercle bacilli cannot create a soil in the healthy individual. The soil is created by suspension of atmospheric influence. Write this in your note book, I solemnly declare it is truth. How, then, does a wife or husband "take" the disease from a partner? By living in the same environment, which is an improper one. This truth was shown many years ago. We have referred to it before. We refer to it again : "From the statistics of the Brompton hospital, collected by Drs. Cotton and Edwards, it has been shown that of the many nurses and others engaged in that institution during twenty-one years, but one nurse and one servant died of phthisis. Especial care seems to have been taken in the Brompton hospital in regard to ventilation and other hygienic conditions. Dr. Cotton's expression is that 'a residence in the consumptive hospital and long-continued working in its wards is a very good way, indeed, not to catch the disease." (Reynold's System of Medicine, vol. II, p. 117, revised by Hartshorne.) It is seen that especial care is taken in this hospital in regard to ventilation, etc. What other hospital has taken like care ? What other hospital has a like record ? It is not that we know less than formerly, but is it not true we have gone daft after a germ theory ; Is it not true our present system of medicine is so Germ-amzed that we think -6 7 ~ of little else except germs ? It is therefore seen if a, b, c and d are trie valid reasons why tubercle bacilli causes tuberculosis, the statement that they do cause said disease is assumption. If assumption be used as a synonym of truth, the conclusion is fallacious. To return, if tubercle bacilli do not cause tuberculosis, how can we rationally say their alkaloid affords immunity ? 68 THE BICYCLE A PREVENTIVE. The world moves on wheels. How rapid the pace. "Art is long and time is fleeting." As we look from our window and see the many swiftly gliding by on wheels, the question arises, how will the race be fitted for the "struggle for existence" in the years to come. On the good to result from the use of the bicycle, as of other things, there is a diversity of opinion. Whether the bicycle prove a benefit or a curse will largely depend on its proper or improper use. Some, predict a future race of humpbacks, with deflected spinal columns, etc. The writer takes a more hopeful view. He thinks as time passes the wheel will be made more specially adapted to individual wants. Each person cannot wear the same clothes. Why should wheels be made so nearly alike? The tall and the stout, the lean and the obese should each have a wheel adapted to his needs. The novelty in use .will wear away. Each will learn while there is celerity in move- ment and time saving in use, there is also a limit to physi- cal endurance. In the future we will be more conservative of our pow- ers. Grace in riding will be sought in the future. We cannot all be handsome. It should be the aim to ever ap- pear at our best. So that taking all in all, we are inclined to think many of the evils now existing in the use of the wheel will pass away. Beauty in the wheel will give way to grace in riding. Rapidity in motion to comfort in using. Novelty to utility and the world will be made better by its introduction. There is a phase in its use on which we wish to dwell. The wheel leads to out-door exercise. The toiling millions have exercise enough, say some. -69— Where is this exercise ? In the dusty shop or ill-ventilated hall. Mechanics, merchants, orators, laborers, all breathe an atmosphere absolutely impure. In this great world of ours, with the vast oceans to purify the air, should we breathe such vile stuff ? No ! A thousand times no ! What are we doing in breathing impure air ? The lodgment of dust in the air cells of the lungs causes sus- pension of atmospheric influence from without. The inhaling of impure or impoverished air causes suspension of atmospheric influence from within. What does suspension of atmospheric influence induce? The precedent state or condition ; tuberculosis in its incipient state. What does exercise in the open air accomplish ? The inflation of the air cells of the lungs and the inhalation of volumes of pure air. 7 he -prevention of the precedent state or tuberculosis Who most readily take tuberculosis ? They who have the greatest suspension of atmospheric influence. Who most readily convey tuberculosis ? The mothers of our land. Mothers, let us have more wheels. They prevent tuberculosis, the greatest evil of civilization and the greatest foe to the human race. 7o- LEGISLATION. A legislator should be argus-eyed. All feel the burden of taxation, have ideas of just and unjust law, and recog- nize the worth of public officials. Taxation should be equal, laws just and officials honest. This the legislator should know. He finds it difficult to place the burden of taxation equally, to know at all times a just from an unjust law, to be strictly honest on every occasion. The law giver may strive to do his duty, fulfill all the necessary conditions, yet be misunderstood or misrepresented by many rivals and fail at the next election. These are a few of the trials or tribulations which every law giver meets. Truly, the legislator should be argus-eyed. He should have great wisdom. Legislation is asked on a subject of which little is known. This is an unjust de- mand. Education should precede legislation. The legisla- tor has the right to ask enlightenment. A subject is clearly understood, yet there is a diversity of interest or opinion. One party asking, another denying, legislation. Here great wisdom or its opposite may be shown. It is a function of the legislator to exercise tact and judgment. In the exercise of these success or failure is as- sured. Barring those cases of exceptional wisdom and tact in the legislator, legislation can advance no faster than the public sentiment which lies behind. In a republic we have no moral right to ignore our laws. It is we, the people, who make them. The legislator is only our instrument. He should be wise. We have spoken of honesty. Without this all other traits or characteristics will fail. No matter how wise, per- suasive or brilliant, if honesty be lacking, no worthy legis- lation can be assured. It may be said if one be wise, he will also be honest. Not necessarily so. There is a wordly wis- —7i— dom without honesty; a love of office or power with evil intention. "A devil's purpose with an angel's face." If, then, we have correctly reasoned, three things are essential in the legislator, viz, many eyes, wisdom and hon- esty. Having spoken of the essentials in a legislator, having referred to the difficulty of always securing proper legisla- tion, and the necessity of education preceding it, we now take up a subject on which a great deal has been said, little formulated, and less put into execution. We refer to legis- lation on tuberculosis. It is the concensus of medical belief that tuberculosis can be controlled. The medical world is shouting this on every hand. L,et the legislator ask the question, in what way can tuberculosis be controlled? Many are silent, more are indefinite, and a few continue to talk without ideas. Some physicians have this latter faculty in an intense de- gree. It is not a faculty to be sought in prayer. Our prayer should rather be, not more words, but ideas. It is evident the method of ridding ourselves of this deadly disease will depend largely on its cause. If we have a large vested interest in bacteria, having traveled and stud- ied extensively at great cost, no doubt it will measurably shock our sensibility and pride to be told that bacteria are of little worth in tuberculosis, and may be ignored entirely in the control of this disease. If the truth is to be spoken, let not a vested interest swerve us to the right or left. Leg- islators should be wholly disinterested. Again, if we hold a chair in some school of medicine, let not the emolument of office or the pride of power prevent the discernment of right and wrong. Let our motto ever be, learn to unlearn that which has been learned amiss. Knowl- edge sought and won in this wa5^ is power. To the thinker, no other knowledge is worthy a place. If rightly understood, we now have a w 7 ise, honest and disinterested legislator. He asks: "What is tuberculosis?" We answer, a constitutional disease dependent largely on the evils of civilization, and governed by the following law: -72— The death rate from tuberculosis is in direct ratio to sus- pension of atmospheric influence, Please observe, in this answer no reference is made to the tubercle bacillus what- ever. According to the writer, then, the wise, honest and dis- interested legislator will take no cognizance of the tubercle bacillus in framing a law for the prevention of tuberculosis. All laws framed will be against the evils of civilization; none against the tubercle bacillus. Says one: "Do we understand there will be no legal notice taken of promiscuous spitting ?" None, whatever. This, we think, is a proper subject for education, not legisla- tion. People should be educated to be cleanly in their per- son, habits and environment. We think one could no more be legislated into cleanliness than into righteousness. Kach is -a subject for education. But says another: "Is it not true that tubercle bacilli are continually floating in the atmosphere ? Must we not prevent this?" Says the writer, it is true that tubercle ba- cilli are found in every atmosphere, more prevalent in some than in others. Two questions present: (i) Can we pre- vent their presence ? (2) Would prevention be of value? On the answers given these questions must hinge all law against the germ. In regard to the first, every medical man will agree that it is absolutely impossible to destroy all microbes or bacteria in the atmosphere. Why attempt the impossible ? Suppose we could destroy all bacteria in the atmosphere, what would it avail ? Bacteria are present in the food we eat and the w r ater we drink. Suppose we could destroy all these ? If it be shown the tubercle bacilli do not cause tuberculosis, of what avail the destruction ? The wide-spread disease tub- erculosis would still be prevalent. With the premises before us, no other conclusion could be reached. The reasoning of the germ theorist is somewhat as fol- lows: Tuberculosis is caused by the plant tubercle bacillus. The more plentiful the germ in the atmosphere, food or drink, the more prevalent the disease, and vice versa. —73— Could we in any way diminish the number of tubercle bacilli, we could diminish the prevalence of tuberculosis in the same ratio. Germicides, control of sputa, etc., dimin- ish the number of tubercle bacilli per cubic foot of air space. Therefore, germicides should be used and the sputa con- trolled. These, therefore, are proper subjects for legislation. This reasoning seems plausible, yet it is fallacious. Let us examine. In the first place, the prevalence of tub- erculosis is not in proportion to the number of tubercle bacilli in the atmosphere. Some will say at once that this is not true. It is true. We have already referred to the observation of Drs. Cotton and Edwards in the Brompton Hospital for Con- sumptives. Conditions in hospital, ventilation and hygiene good. Number of years in observation, twenty-one. Number of attendants who died of the disease, one nurse and one servant. Conclusion: "A residence in the con- sumptive hospital and long-continued working in its ward is a very good way, indeed, not to catch the disease. Take the same conditions except ventilation. Think you no attendants would have died ? All attendants would have died of the disease. Why? Because imperfect venti- lation is suspension of atmospheric influence, or a condition in which the living tubercle bacilli enter the system and grow. In the two cases wherein is the difference? Opening or closing a window or door does not alone determine the absence or presence of tubercle bacilli in the atmosphere. How foolish ! There must be something else. What is this something else? It is the -perfect ventilation that renders the system immune. Here is the immunity long sought, not an injection. It is the imperfect ventilation that ren- ders the system a fertile soil. Hence the law of tuberculosis. The corrected proposition, then, reads: "The preva- lence of tuberculosis depends on ventilation, not the number of bacilli." This is an important consideration, one which the biologist would do well to stop and investigate. We hardly look for this at present, he is so thoroughly imbued -74— with a germ theory. In the second place, tuberculosis is not caused by the plant tubercle bacillus. We have spoken of this in other places. We endeavor to be brief at this time. It is evident to any thinking mind that a plant cannot precede the soil in which it grows. Please consider: The tubercle bacillus is a plant, the soil is the being in which it grows. The being in health does not have growing bacilli. Why not? There is no soil. So soon as suspension of atmospheric influence takes place in said being so soon a soil is present and so soon the tubercle bacilli take root and grow. Is this plain ? When the ventilation is perfect there is no soil, and consequently no growing bacilli. This is true, no matter how few or many tubercle bacilli are in the atmosphere. If, then, the ventilation be perfect, there is no danger whatever of catching the disease tuberculosis. In this condition the tubercle bacilli are perfectly harmless. We are writing to rational beings. How, then, ought we to proceed ? Attempt to destroy the harmless tubercle bacilli, or render the ventilation perfect ? Which view ought to engage the attention of the wise, honest and dis- interested legislator ? There can be but one answer, legis- lation should be for better ventilation, l^eave the tubercle bacillus alone; it needs no care. In the course of events, as tuberculosis becomes less prevalent, through a purer atmosphere, the tubercle bacilli likewise become less. Whether few or many, it matters little if the ventilation be correct. What, then, shall we say of germicides and the control of sputa ? Germicides are of little worth. It is not neces- sary to use them. Tuberculosis can be controlled in a bet- ter way. Every one should care for his sputa, but the care of it is not a proper subject for legislation. "Cleanliness is akin to Godliness." Cleanliness should be taught. If the writer' s conclusions be correct the reasoning of the germ theorist must be fallacious. What, then, is a proper subject for legislation ? Ventilation. In order to present this subject in a clear light perhaps —75— one or two illustrations would be proper. In referring to these it is not to condemn any particular system, but simply to illustrate. The cases chosen are the ones which come most readily to mind. In the elevated railroad of New York a method of rapid transit is in vogue that is unsurpassed in this country. The trolley or horse car of other cities is excellent. All these systems have one fault, viz., the ventilation of the crowded car is poor. The writer has been on the New York road when every inch of available space was occupied ; no room to stand. The same may be said of the horse car line on Broadway as it was a few years ago. This condi- tion of things ought not to be. The situation seen in New York is seen in many other large cities. Every seat in a car should have a proper air space for its occupant. Every occupant should be given a seat. Then the question of ventilation is settled at once and forever. The ventilation of the car should also be perfect. In short stops and fre- quent changes this would be materially aided by frequent opening and closing of the doors. In long runs the case is different. Here the most perfect ventilation should be secured. One source of annoyance in long distances in the irritant dust. How to eliminate this and at the same time secure perfect ventilation is a question for science. Its present aim seems to be how best to catch, destroy or elim- inate the bacillus. The writer thinks its field of action should be changed. But ill-ventilation is not seen in the car alone. It is seen in the hall, church or shop; in truth, wherever people congregate. It is also seen at the fireside in the home. When will we learn wisdom? "Wisdom is the principal thing; therefore get wisdom." It may be said the question of legislation, in regard to ventilation, is a complex one. It is complex, yet it is very simple. Pure air is abundant. It is also free. Why should there be difficulty in obtaining it ? The first ques- tion to consider is one of desire. Do we, as a people, desire pure air ? If it be best for us to have it, if it be abundant - 7 6- and free, why should we hesitate ? It seems to the writer it is a question of education alone. There are many things we earnestly desire. They cannot be obtained, or if received they spoil us or injure our health. When a necessary is to be had at so little cost we should reach out our hands and receive or demand it as our right. This is American. We are taking a journey. The car or boat or bus is crowded. One passenger desires pure air; the rest are satisfied as it is. The conductor or captain or cabman is asked to open a window or door. Many at once object for fear of taking a cold, and the window or door is closed. All suffer from the closure. Do we not need education ? A consumptive or one having a cough enters this crowded car or boat or bus. He coughs or expectorates from neces- sity. The one in authority says: "My dear sir, or madam, you must not spit in this car." "Why not? Havel not purchased a ticket?" "Your ticket is all right, but you must not cough and expectorate while on this car." "My dear conductor, why do you not give us pure air?" "You talk to the authorities about that." The authorities are investigated. "We are perfectly willing to conform to any reasonable public demand. Scientists tell us there is great danger from dried sputa. It becomes disseminated through the air and causes consumption, etc. Scientists are silent as to ventilation." Do we not need education ? We certainly must edu- cate before we can legislate. Legislation without public sentiment behind it is a dead letter. Education and legis- lation, like twin sisters, walk hand in hand. What, then, shall a traveling public demand of its car- riers ? Perfect ventilation, abundant air space and a seat for all. How shall we render our halls, churches, schools, etc., less dangerous ? By having them more perfectly ventilated. This can be accomplished in many ways: (a) I^ess seating capacity or larger air space; (b) better heating apparatus, in that less atmosphere of the room is impoverished, i. e. } —77— by having greater heating surface and less intensity of heat less oxygen is abstracted from the air in the room; (c) an abundant supply of pure air partially warmed before enter- ing the room; (d) an exit for all vitiated or impure air. These taken collectively, with a proper construction of the building or room, will fulfill all needs. Many churches or halls are erected as to external ap- pearance or acoustic properties. While these must not be lost sight of, the ventilation of the building is of far greater importance. The life of the audience is of more value than the beauty of structure or voice of speaker. Architects, in making designs, should think of this. What shall we say of the home ? Our home is where we live or abide. Where is the home? In the country or city? Is it our own or another's? Or, rather, do we hold or rent ? The answer to these must modify the answer given. If in the country there, is greater opportunity to breathe pure air. The same may be said if the home be our own. In rented flats or rooms in the city we receive that for which we pay. If able to pay we receive the best; if unable to pay we must take that which we can get. With the poor wage earners it is often take the poorest or none at all. How comfortless are these ! How illy ventilated ! Often, how short lived the occupants ! Cannot legal re- straint give them better homes ? We have often thought in visiting country homes, what a field for cultivation ! How lovely and pleasant some of these homes are ! What taste and munificence ! Yet oft- times it is outward adornment like dressing the hair or body, not that inner fitness so essential to worth or useful- ness. Seldom does the architect or builder think of that inner adornment — ventilation. What a pity ! In other homes, how destitute and comfortless ! The home is a mere hovel or shelter. It is not the elegant home that confers health and longevity. Frequently it is the poorest. One log cabin the writer recalls, which contained a large family. It was so open the stars could be seen through the wall on either side. - 7 8- Yet that family lived in that home many years. Little sick- ness, plenty to eat and do made that home a happy one. The family grew to manhood and womanhood, separated and organized homes of their home. How beautiful the picture ! This is not seen in every home. —79" CONTROL. Of all historic diseases which have afflicted mankind, no continuous disease has been less subject to control than tuberculosis. There have been epidemics or endemics that were more fatal or less subject to control for short per- iods of time. But these have been only for short periods. These diseases die out for want of fresh fuel, or their very contagiousness has demanded great effort, which has re- sulted practically in control. With tuberculosis the case is different. This is a dis- ease with which we all are practically familiar — one which every medical man thinks he understands. The very clear- ness of apprehension with which he thinks he sees leads him blindly on in treatment or prevention. Hence no stop or cure. It is a common impression that tuberculosis is due to a germ. If true, the germ being killed the disease would at once cease. Methods of destroying germs are familiar to all. It is plain to the ordinary observer they are of little value. Germicides -per se being valueless, it enters the minds of some that perhaps a condition of the system may be induced that will prevent the entrance of germs, or — may be better — will not allow their growth. Germ cul- tures are procured and their alkaloids used to fortify the system or render it immune. With a pains- taking accuracy worthy a better result, these germs are isolated, cultivated and the alkaloids injected for this purpose. The result is before us. Is tuberculosis lessened by injections of these cultures? There are many occupying chairs in medical colleges who would be pleased to answer in the affirmative, but facts do not bear out the assertion. Instead of boldly saying no, which would be the writer's course, the attempt is made to waive a direct answer to the -8o— question and encourage a hopeful view for the future. At the same time these teachers are continually instructing in methods which have long since proved practically nil. Is such instruction a benefit ? Finding it impossible to kill the germs in the air or in the person without injury, rinding immunity largely an imaginary quantit} 7- , men have in some quarters advocated germ-proof houses. It is soon seen by all except a few fanciful scientists that even these germ- proof buildings could be of little value. The question now arises: If present notions prevail, how soon will tuberculosis be under control ? No one can clearly answer,' for no one knows. Under the circumstances, would it not be wisdom carefully to investigate the cause of dis- ease and see if there be not some other connecting or under- lying condition which allows the living tubercle bacillus to enter one's system and grow? If such condition be found, would it not be further wisdom to inquire if this condition is always present in the growth of tubercle bacilli in the human organism ? If always present, would it not yet be further wisdom to ascertain if this condition cannot be re- moved, and thereby prevent the entrance of a growing bacillus in one's system ? If this condition exists, is always present, is removable, we hold in our hands an effectual weapon for the prevention of tuberculosis. The writer claims that here is a succession of facts the force of which cannot be weakened by any argument. In other words, here lies a chain of reasoning on which the law of tuberculosis is based. This law is based on facts as immutable as is any law of Kepler or Newton. This law must stand. What is the law of tuberculosis ? The death rate from tuberculosis is in direct ratio to suspension of atmospheric influence. Having laid down a law of tuberculosis, let us now critically examine the facts on which this law is based. My attention was called to these many years ago. The first published article bearing on the subject is found in the December number of the Cleveland Medical Gazette, 1890. Phthisis pulmonalis is here spoken of as a zymotic disease. Medical experts had so placed it, and this opinion was ac- cepted without question. Upon investigation the contag- iousness of the disease was in doubt. It was found there are certain conditions of the system in which one apparently takes the disease. There are other certain conditions in which one does not take the disease. The question arose: On what does the contagiousness or non-contagiousness of tuberculosis depend? In answer to this, it is seen that cer- tain animals are affected and the same animals are not affected, according to the condition in which they are housed or kept. Some in authority have lately asserted that food or diet has as much to do in the origination or starting of tuberculosis as has the atmosphere. The writer thinks that in this statement there is a misconception. It is not the atmosphere -per se, but suspension of atmospheric influence that induces the condition or disease. Food or diet, according to quantity and quality, may improve or weaken the physical or mental condition. This, I think, is about all. Suspension of atmospheric influence, whether the animal be weak or strong, will produce a condition of the system which allows the tubercle bacilli to enter and grow. While suspension produces a condition favorable to the growth of a germ, food produces simply a strong or weak condition of the system and has no relation to the germ's growth whatever. This, I think, is a marked difference, and one which even late observers have entirely overlooked. Again, it is evident that if the basic facts be changed, the law depending on those facts must be worded differently. This accounts largely for the change made in the law. Another fact may be referred to at this time. It is very difficult for some to enter into a discussion or investi- gation in which figures or mathematics are used. In order to accommodate this class, the law is stated in the simplest language possible. The writer feels assured that those who impartially investigate the subject will find the conclusions accurate. With this simple law before us as demonstrated, with -82 — the deadly disease before us as seen, it is the writer's hope and belief that much may be accomplished in a practical way by simply living in accord with the teachings of this law; by avoiding in every possible way the suspension of atmospheric influence. A deadly enemy is before us. In every engagement thus far we have met defeat. Let us train our guns to do the most effective work. Before enter- ing an engagement it is always well to take an account of the character of weapons to be used. One great difficulty in the recent past has been that the bacteriologists have taken upon themselves the entire work. This I think is a mistake. Bacteriology is one arm of the medical service. Its work along its own line is of great value; its work in other lines of no value whatever. To illustrate: We have many ships in our navy — bat- tleships, cruisers, torpedo boats, etc. Suppose a captain of a torpedo boat should say, "My boat will act as a battle- ship." Or the captain of a battleship should say, "My boat will act as a cruiser." Or the captain of a cruiser should say, "My boat will do the entire work; the rest of you may remain idle." What would be the condition of the navy ? Any one could see that the service would be of no practical benefit whatever. We might as well do with- out a navy as to have one boat arrogate the entire service to itself . Thus with bacteriology. Bacteriology has been pushed forward to the exclusion of everything else. I trust some of my contemporaries will see the force of this assertion. There is another insuperable difficulty which bacter- iology has met in the battle with tuberculosis. It is as- sumed that tuberculosis is a germ disease. If it were a germ disease, rationally considered, it could be met with germicides or the alkaloids of germs. It not being a germ disease, rationally considered, germicides or alkaloids of germs would be of no value. Whether the disease be due to a germ or not, I leave to an intelligent profession; this much is certain, bacteriology has thus far found no cure for the disease. The same may be said of other methods of -8 3 - treatment. The writer believes that the secret lies in recognizing the cause of tuberculosis. It is plainly evident if the cause of tuberculosis be suspension of atmospheric influence, no line of treatment could cure without first recognizing the cause and removing it. Even then, if there be destruction of tissue, no treatment could restore tissue lost. These facts must be taken into consideration when talking of cure. So that he who asserts he has a cure for tuberculosis either falsifies or is ignorant. There being no cure for tuberculosis, it remains to be asked : In what way can we arrange our forces most effect- ually to battle with the disease ? To the writer it seems clearly evident that the control of the disease must be large- ly along the line of prevention. Now do not misapprehend. The writer believes that open air and constitutional treat- ment are of great value. In truth, in conjunction, they are the best treatment of tuberculosis known to the science of man. At the same time, to repeat a well-worn aphorism : "An ounce of prevention is worth a pound of cure." There is no cure for tuberculosis. There is prevention. If pre- vention succeeds, there is no need of cure. Today this hy- dra-headed disease exists on every hand. There is need of prevention and there is also need of treatment. Insiduous and deadly in its nature, say not to the afflicted that there is no value in treatment. There is value in treatment. But if cure be perfected, treatment must be given in the prece- dent state or incipient stage of the disease. Then there is cure. But, as said in a previous article, if there be disorgan- ization or breaking down of lung tissue, this tissue can never be restored. Yet even in this condition treatment is of value and by its judicious employment life may be prolonged, and aid and comfort given the afflicted. This elone is cer- tainly worthy our consideration. To speak directly of prevention, the first step to be taken is to remove the cause of the disease. If the disease be due to suspension of atmospheric influence alone, the first step in prevention is to remove the suspension. With- out this, nothing can be accomplished. With this, much -8 4 - can be accomplished. If due to heredity in conjunction with suspension, here the battle must continue as long as life lasts. Heredity is an entity of the parents, and must be controlled in the rising generation by proper marriage. Let no one marry into a consumptive family, should he de- sire healthy offspring. Evidently the marriage relation is a serious one if we look at it in the light of transmission of disease. Every one who asks in marriage should have a clear health register and he should expect the same of his partner. Without this, tuberculosis will remain a disease in the human family to the end of time. With this, tuber- culosis can be controlled. In a recent session of our legislature some one intro- duced a bill to regulate marriage. What became of the bill the writer only conjectures. One thing is known — the way in which the measure was received. Some spoke of it as ahead of the times; others as visionary, unnecessary, ridic- ulous, etc. It is not worth while to discuss the merit of this particular bill. This much is certain: In the years to come some measure of this character will be enacted to pre- vent disease. Education must ever precede legislation. It is education today, legislation tomorrow. In this way, step by step, the human family has risen in civilization. The laws of Ohio today could not be enforced in present China. The laws of Ohio, it is hoped, will be changed for the better in the years to come. True, it is difficult to legislate on marriage. To say one must or must not is somewhat arbi- trary. Is it not best to do so ? When one is educated to select only the best in marriage, it is more largely a matter of choice or judgment and less one of impulse or emotion. Not long since a man of this city, pointing to a deformed child, said: "If nature could give me no better body than has that child I would ask to be shot/' Please reflect ! What was nature's act other than the volition of the par- ents ? Why not legislate ? Reverting to suspension of atmospheric influence, this may be induced in many ways. The following classifica- tion presents the subject in the clearest light possible. SUSPENSION OF ATMOSrHKRIC INFLUENCE. atmosphere { D1 ventilation > vocation,etc. From without 1 T ., , j Over-heating rooms, im- I atoolphere { Proper ventilation, etc. From within (Defective f 0ri S inal {Heredity. Di< ure, etc. ) jjerecnve J ( | lung tissue | Acquired> (Disease, expos To explain more fully, suspension takes place in two ways — from within and from without. From within through original or acquired lung tissue. Though the scalpel or microscope may detect no difference in lung tissue, it is observed that children of consumptives take the disease more readily than children of the healthy. Why? Defective lung tissue — heredity. Such children will tolerate no confinement. Confinement to them means death from tuberculosis. These children die from the dis- ease, while other children escape — ventilation, food, phys- ical exercise, etc., being the same ; thus showing that there is a difference in the organism or lung tissue. It is also ob- served that those having stenosis of the air passages whether congenital or acquired, are more subject to tuberculosis t Why ? Suspension of atmospheric influe nee. In some of these cases operation to remove the stenosis is beneficial. In all, there should be perfect ventilation. There are certain diseases which tuberculosis is pretty sure to follow if precaution be not taken, viz., measles, pertussis, etc. Why? Defective lung tissue— acquired. Suspension of atmospheric influence due to thickened lung tissue. What precautions are necessary ? Perfect ventila- tion during sickness and recovery. From without, through impure or impoverished atmos- phere. Every observer has noticed that there are two classes in particular who suffer much from tuberculosis — they whose vocation or calling keeps them continuously in the dust and they who suffer from confinement in ill- ventilated rooms. In the first class there is suspension from lodgment -86— of dust particles in the air cells of the lungs or from me- chanical irritation of the same — one or both, commonly both. What is the preventive ? Avoidance of the irritat- ing dust, (i) Change of vocation; (2) wearing of adust protector; (3) elimination of dust by a dust collector. If heredity be a factor, the first method should be adopted. No one should engage in or follow an unfavora- ble pursuit if the subject of hereditary influence. Though the usual precautions were taken, the probability is he would die of tuberculosis. If the subject be vigorous and have a good family history, he may follow the vocation of his choice. In this case a dust protector is of service, but unequal to a dust collector. In all shops where there is an irritating dust these collectors should be obligatory. We now reach the topic of impure or impoverished atmosphere. This has been explained elsewhere, but a word or two in this connection will not perhaps be out of place. We, as Americans, are living in homes many of which are warmed by furnace heat. In all homes there is artificial heat for a part of the year. In these homes the atmosphere is at times impoverished. As a result the occu- pants suffer largely from respiratory and constitutional dis- ease , Tuberculosis is of this number. It is prevalent and deadly. Treatment is of little avail. Prevention is of value. The preventive, the writer is inclined to believe, consists in a stove or furnace of at least double the size or capacity of the one ordinarily used. It takes no more fuel, the heat is more constant and even, and the stove or fur- nace lasts longer. There is, therefore, no greater expense in the end. There is an assurance of better health. The danger in cold weather is that too much oxygen is with- drawn from the room to support combustion, and not enough air is let in to replace the oxygen abstracted. Suspension of atmospheric influence is induced. In this way plants and animals alike suffer. There is another factor which should engage our atten- tion. I refer to the irritant dust of soft coal stoves and furnaces. In the present arrangement of these, nearly all -8 7 - give off an irritant dust, smoke or vapor. Irritation of the throat, fauces and bronchial tubes commences soon after their use. This should not be. The draught should be perfect, so as to allow no dust in the room. If it is not perfect, there is suspension of atmospheric influence because of the irritant dust; also because of the lack of oxygen in the air. Consequent tuberculosis. When these facts are clearly understood and acted upon, the writer feels satisfied the death rate from tuberculosis will be much diminished. If true, this statement is worthy of consideration. In the above I refer to the atmosphere as found in country homes and villages. In large cities, as a rule, it is very much more impure. Large cities are railroad centers, contain the factories, workshops, etc. There are, of necessity, great volumes of smoke. At times the outdoor air is almost un- endurable. Science can and no doubt soon will remove this smoke nuisance of cities. There are other factors, not mentioned, in cities which contaminate the air and render it unfit to breathe. I pass over these. One or two others I mention which aid respir- ation and whose absence makes breathing more difficult. I refer to public baths and gymnasiums. To conclude, if the person be kept clean, a certain amount of physical exercise be taken, and pure air constantly inhaled, there is no danger whatever from tuberculosis if there be no heredity. Tuberculosis can be controlled. -88— STATUS OF THE BACILLUS "The bacteria are now admitted to belong to the veg- etable kingdom and to constitute the lowest forms thereof." — Dr. K. O. Shakespeare. There is a law of vegetable growth. Rationally con- sidered, the low form of organism or its microscopic nature does not militate against or invalidate this law. In other words, there are certain conditions which must be complied with in the growth of perfect vegetation. PLANT LIFE. (a) Conditions of Growth. Heat, solar or artificial, is necessary in the germination of every seed and in the fructification of every plant. Without heat plant life or plant growth lies dead as inorganic matter. There must also be moisture. Heat may awaken a latent energy in plant life, but if continued without mois- ture the agency that awakens destroys. Light is also a potent influence. Heat may awaken life, moisture may continue life, light alone perfects and thereby perpetuates the life begun. In the continuation of plant life these three factors are always present, and, so to speak, in an intense degree. No one of the three factors can be ignored. The bacteriologist with his culture media, etc., etc., recognizes these principles and applies them more or less in his field of labor. We say more or less. Heat is necessary; the temperature below a certain point little change takes place in the culture media. Moisture is necessary; no growth can develop without mois- ture. Light is necessary; with a perfect action of the other two, light is essential to fruition. In the construction of the ordinary culture oven, if a provision be not made for the generous admission of light, will the vegetation be a perfect one ? At the end of an in- -8 9 - definite series, a culture becomes attenuated. In what way ? There are many things a flood of light would illuminate. But hold ! The tubercle bacillus dies in the sunlight. "The tubercle bacillus dies under sunlight, in thin lay- ers in the course of a few minutes or hours, but perishes under diffuse daylight only in the course of a week." — Dr. Jas. T. Whittaker, Ohio Medical Journal, July, 1895. One other condition is necessary — a suitable soil. This will be referred to later on. (b) Modified by Environment. — Observe trees in a dense forest — tall, straight and without limb until near the top, in the crowded fence row — fan-shaped, with limbs to the earth; in the open — short, with branches extending in all directions. That a variable condition of the tubercle bacillus is due to environment is shown in an article in the Cleveland Med- ical Gazette, June, 1894, by Dr. C. W. F. Muenchehofe. (c) Elective in Location. — Sitting in a wood in Wes- tern Illinois I counted fourteen varieties of lumber trees on less than two acres in area. This is remarkable. Seldom do we see more than three or four varieties on so small a space. There are forests of oak, pine, cypress, etc. Often several kinds are intermingled, but usually one or two kinds predominate. The reason for this absence or predominance is prob- ably plant dislike or affinity for certain soils. We know from observation that native trees do not thrive equally well in all localities. There are certain spots in w T hich native trees refuse to grow. Change but a few 7 rods distant and 'at once they begin to thrive. Seeds from forest trees are scat- tered year by year in these waste places. They fail to take root and flourish. The voice of plant life is the voice of the maiden: I marry, but not w T hom I dislike; I grow but with affinity. In the distribution of bacteria man} T species are often found in the same tissue. "Different species of bacteria are so frequently asso- ciated together in substances that afford them nourishment -go- that some method of separation is essential for intelligent study, etc." — Dr. Shakespeare. At other times well nigh pure cultures are found. ''The main habitat of, the tubercle bacillus is the lungs and the sputum is sometimes almost a pure culture." — Dr. J. T. Whittaker. One of the greatest difficulties in the past has been to isolate in order to cultivate. It is thought this difficulty is now entirely overcome. With the removal of one barrier another appears. It is found the germ takes root in some soils and in some it does not. The reason for this affinity or dislike can only be conjectured. Instead of explaining in a perfectly natural way by saying it is owing to drainage or chemical constitu- ents of the soil, there arises the strange hypothetical doc- trine of phagocytosis, which is in substance that on the part of host and invader armed battalions are constantly on guard. On the least provocation a free fight begins. As neither party will yield, it is a war of extermination. It is readily seen how such a theory could arise on the continent. It is an every day picture.. It is not so clear how such a theory could become established among intelli- gent Americans. But it is simply wonderful the amount of trans- Atlantic idol-worship that is present among us. On this topic, as many others, revelations will arise. It is to be hoped they will be more in consonance with rea- son and common sense. (d) Absorption. — This topic is taken up with a degree of trepidation. Plant growth is shrouded in mystery. What the vital principle, when enters it the plant, how transmitted to the seed, death occurs in what way ? — these and many other questions are as mysterious as life and death in the individual. The diversity in growth is involved in mystery. Two children, born of the same parents, reared with the same care, grow up together — the one virtuous, the other vicious. Mysterious ? Not more so than the growth of plants. Two seeds from the same tree are planted, the soil,, —9i — moisture and sunlight alike to each, The one is straight- grained, the other twisted. Mysterious ! Perhaps the child, by bent of inclination, received the vicious tendency and grew as moulded. Perhaps the embryo tree met some obstruction and turned in growing, remaining thus as tree. Mystery when made plain is mystery no longer. The growth of plants indifferently from the same soil is somewhat mysterious. The beech, the maple, the oak, grow side by side. It seems there must be a difference in the elements assimilated. How diversity of labor is performed on the same food is mystery. Three persons sit at the same table. One rises an orator, another a hod-carrier, the third a nothingness until the next meal. It seems there must be a difference in the elements assimilated. There is a difference. All living organisms grow by absorption, or perhaps better, assimilation. To the vegetable world the soil is the food. Suitable soil means proper elements properly prepared. Whether the soil be prepared by the care or folly of man it matters not, nature [appropriates as found. This thought should carefully enter the mind of every one seeking a cause or cure for tuberculosis. There is a difference. Each plant takes the element best suited to its nature, leaves the rest. One has more, another less. All must eat or die. Example: Mr. R. plants a field to corn for eighteen consecutive years. The field is occasionally fertilized as others. Year by year the crop of corn becomes less and less. On the eighteenth year there is a good growth of fodder, but no corn. The soil for corn is exhausted. Without fer- tilizer the same field yields a large crop of oats the ensuing season. Here is a lesson showing the value of rotation in crops. No doubt each tree takes nourishment appropriate to itself and leaves the rest. Another tree absorbs from what is left. In this is seen a gathering up of all, or Nature's providence. - 9 2 — But, however rich a soil may be, it avails nothing to the growing plant unless it be rich in assimilable elements. To this subject my attention was early called in planting trees. All things considered, those trees grew best which were planted with the greatest care, in having all rootlets well cared for and the earth well pulverized around them. This much for soil constituents. In two articles on malaria, published in the Cleveland Medical Gazette, September, 1891, and April, 1895, the question of plant absorption of an element extraneous to the soil is dealt with. This must suffice for the present. Much as is known of the life history of bacteria, their growth is involved in mystery. Why arise these micro- scopic organisms ? Is their office eliminative or destructive ? Does their presence in disease constitute the disease fer sef When once in possession of a soil, can the soil be reclaimed ? These and kindred questions may be asked in all earnest- ness, and yet the answer be a hollow mockery. The presence of the bacteria in disease — causal — and the presence 'of the same bacteria in health — harmless — is mysterious. Mystery made plain is mystery no longer. If we look upon the bacteria as vegetable organisms — and the highest authorities in the land view them as such — the way is clear. As already stated, all organisms grow by assimilation. The presence of a growing organism implies the presence of assimilable food. The presence of assimilable food implies a something before the organism takes root. Which has the priority, the something or the organism ? Will some bacteriologist please tell us in what this some- thing consists ? Mark the issue, in this something exists the cause of tuberculosis. Control this something and you control the disease. Can tuberculosis be controlled ? Per contra, the pres- ence of a living organism — not growing — implies the con- ditions are unfavorable for growth, for it is as natural for organisms to grow under favorable conditions as it is for the sun to shine or water to seek its level. If, then, other —93- conditions be the same, in health as in disease, the growth not being the same, the cause or causes must be sought in the soil. Other conditions, light, heat and moisture, are supposed to be the same. A fair deduction then, is, the difference in growth is due to a difference in the soil. If, then, we take this rational view of the question, it is unnecessary to consider the hypothetical doctrine of phagocytosis at all. In other words, the peace of Europe does not demand an armed intervention. But say some, "The tubercle bacillus is a parasite.'' What is a parasite? We will let the Standard answer: (i) "A living organism, either animal or plant, that lives on or in some other organism from which it derives its nourish- ment for the whole or part of its existence, as a louse, tape- worm, mistletoe or dodder." Yes the tubercle bacillus is a parasite, One question please: Did you ever know of a person's head being so healthy that a louse could not live on it ? Does the mistletoe invariably grow most luxuriantly on the tree half dead ? Look around you. Did you ever hear of a tape-worm being found in a healthy -primes vice? Does the potato beetle always select a sickly potato ? "Come, let us reason together." Why does the tubercle bacillus select a sickly subject ? Why does the tubercle bacillus fail to grow in the health y subject? "Your reason, Jack, your reason." "What ! upon compulsion ? Yes, armed phagocytes at the portals. The changes produced by the tubercle bacilli are mys- terious. "The body which we term a 'tubercle' presents in its earh- formation nothing distinctive or peculiar, either in its components or in their arrangement," — Dr. Osler. i. £., before bacilli enter or are planted, "tubercle" is the same wherever found. The bacilli enter. "The bacilli then cause, in the first place, a prolifera- tion of the fixed elements with the production of epithelioid —94— and giant cells; and, secondly, an inflammatory reaction, associated with the exudation of leucocytes. How far the leucocytes attack and destroy the bacilli has not been defi- nitely settled." — Dr. Osler. The writer has a simple taste, but he thinks when a plant takes root it begins to grow; that in growing it absorbs nourishment from the soil; that whatever the plant gains the soil loses. There must be change while the growth is going on. Change can be detected. All pathological talk has been on what is found in or after growing. What is taken up by the plant ? What is lost to the individual ? These are questions that should be answered. The "agreement" of modern pathologists is mystical. Illustration : "Modern pathologists have agreed in this r that only such products, though histologically the same or similar, as contain and result from the specific bacilli, deserve the name of tuberculosis. Thus tuberculosis is defined an infectious disease." — Dr. A. Jacobi. Suppose the farmers of Ohio should agree that, inas- much as a horse has so many excellent traits, he shall henceforth and forever be called a man. As a result of this agreement would the horse hereafter walk on two feet ? While it is perfectly right and proper for the patholo- gists or farmers to act as in the premises, their action or in- action makes no change as to facts. The- horse still re- mains a horse. Pathological agreements are not solid rock against which the medical writer can indifferently place the Archimedian screw. This is a question of mal-absorption or assimilation. Theological writers have been accused of cultivating a third eyelid. Medical writers have, and use, only two: Schliesze bcide Atiglein zu. (e) Diffusion . — The earth teems with life in the springtime, when plants drink the moisture and sunlight. The air teems with life in the summer, when plants give the world their fragrance. —95— Plant Absorption and Diffusion . — Thus is taught a great lesson in nature: Secure, give. Man has perverted this lesson: Acquire, hold. It is not primarily a lesson in charity we desire to teach; the rather, to study plant diffusion and observe the lesson therein taught as closely as we may. Perhaps this study can be introduced in no better way than by an illustration; The city of Ravenna, O,, has a water supply inferior to none in the state. Drawn from Crystal lake, it is dis- tributed through mains to various parts of the city* Being soft, clear and pure, it is satisfaction to all who use. At a certain season of the year, and for eight or ten da3 T s, usu- ally in July and August, the water has a peculiar taste. I am told this taste is due to vegetation in the lake, which blossoms at this period. Since the intake has been supple- mented by wells in the immediate vicinity of the lake the taste of the water is not so marked at the period named. At any rate, if my informant be correct, here is a clear case of plant diffusion through water. The aroma of flowers, of birch, pine, etc., is familiar to all. Diffusion Through the Air. — If our senses were acute enough to perceive them, no doubt constant change could be detected in the soil, due to plant absorption and diffu- sion. Our natural sense is too dull to perceive them, and the chemist is bafBed in detection. Query: If growing plants diffuse an entity to surround- ing media, Cannot the same action take place within as without, the body ? Or to put the question more directly If growing plants diffuse to a fluid media, cannot living bacteria diffuse to the fluids of the body ? If yes, may not these diffusions markedly affect the organism containing said bacteria ? Let us examine. "Recent chemical examinations of the contents of pure cultures of various pathogenic and a few other bacteria have shown the existence therein of certain peculiar poi- sons, not only possessing specific physiological action, but also having peculiar chemical properties and constitution.- - 9 6- which ally them more or less closely to certain well-known poisonous vegetable alkaloids. These chemical bodies have been named ptomaines." — Dr. E. O. Shakespeare. The willow is a native tree of North America. In the United States many of these trees grow along the banks of the smaller streams. As an anti-periodic the willow has long been known. The medical properties are found in the bark. In 1825 Fontana declared the active principle to be salacin. Ptomaines and salicin are then similar in each being developed in the living plant. "Pathogenic bacteria have been killed in their pure cultures by the action of heat. * * * The culture medium then injected, produces a series of symptoms, etc." — DR. SHAKESrEARE. Willow trees may be boiled, /. air treatment. Is tuberculosis contagious? This question is often asked by near relatives, friends and attendants; those who directly minister to the wants of the patient. As a question, it is a perfectly proper one and should be answered in all sincerity. Before directly attempting an answer, perhaps a pre- liminary statement is necessary. Among civilized nations, tuberculosis is found in nearly every locality, is fatal in its nature, and is by some thought to be on the increase. Since the advent of the germ theory of the disease many worthy people have held tuberculosis should be isolated as variola, etc., on account of its contag- ious nature. These people have even invoked the aid of law to prevent contagion — to protect the healthy. Is tuberculosis contagious ? The word contagious is used in its ordinary sense. By, —153— is a disease contagious, is meant, is a disease catching ? Can one take the disease from another while staying in his house or rOom as nurse, or doing the ordinary work of the household ? In other words, does one ordinarily take tuberculosis while pursuing these vocations ? Is tuberculosis contagious ? John Smith is twenty-seven years of age , has a loving wife with five small children and the disease tuberculosis. No insurance. Mrs. John Smith is twenty-five years of age, of nervous temperament; does the work of the house but has heard of the germ tubercle bacillus. Mrs. S. thinks dearly of John, but occasionally thinks of herself and fam- ily. Very natural. She consults her family physician, who is a germ theorist. ''Doctor, I am afraid of catching this disease. Is tub- culosis contagious?" "Madam, your question is a very timely and pertinent one. I have been in attendance on your husband now for about one month. There is no question whatever as to the nature of his disease. Had thought several times of telling you to be more careful, but I have been busy, extremely busy. . Mrs. S., you ought not to enter your husband's room. There is great danger of the tubercle bacilli enter- ing your system." "But, doctor, what shall I do ?" "You ought to hire a nurse at once. A competent and thoroughly trained nurse; one who clearly understands the situation." "But, doctor, how shall I pay him?" "Really, madam, I do not know. The law makes no provision." "Doctor, will the nurse not take the disease ? If the bacilli enter my system, will they not enter the system of the nurse as well ?" "Madam, you do not understand. The nurse will take proper precautions." "Well, doctor, can you not give these precautions to me ? Why hire a nurse?" - 154— "You have thus far discharged the duties of nurse. Your work has been done well, yet there are certain precau- tions that should be observed. All sputa should be burned. The object in this is two-fold: To prevent contagion on the part of attendants and to prevent reinoculation on the part of the patient." . » "Doctor, since my husband's sickness I have burned all sputa, as an act of cleanliness. ' ' "As I said before, you must not enter your husband's room. There is great danger." "Doctor, in what does the danger consist ?" "What a question ! In what does the danger consist? The air is full of living tubercle bacilli. The danger con- sists in these bacilli entering the system and causing tuber- culosis." "But, doctor, does not all air contain tubercle bacilli ? Why should I be denied entrance to my husband's room?" "True, the tubercle bacilli are ubiquitous, but they are not so plentiful elsewhere as in your husband's room." "Doctor, how many tubercle bacilli does it take to start tuberculosis ?" "Well, really I do not know, but I suppose one or two would be all that is necessary." "Doctor, I have read there are many microphytes in the ordinary atmosphere. Now, according to your theory, in order to prevent tuberculosis, one would have to stop breathing." "Madam, there are so many things you must learn from experience. As I said before, you ought not to enter your husband' s room. ' ' "But, doctor, how shall I attend to his wants?" "By means of a telephone. So far as I know, no ba- cilli travel by wire." "Doctor, shall I convey his food and clean linen and arrange his bed by telephone ?" "Certainly, madam, certainly." "Doctor, ought. I to wear deceptive gloves while mak- ing my husband's bed?" —155— " Deceptive? You mean aseptic. There are so many mistaken terms in science." "Doctor, you say my husband's room is improper in that it contains multitudes of tubercle bacilli. What would you say to a larger room with more perfect ventilation ?" ' 'Madam, this is not in accord with approved treatment." "But, doctor, would not a larger room with perfect ventilation lessen the number of tubercle bacilli per cubic foot of air space ? Would it not render the room more fit for a nurse to enter ?' ' "Robert Koch, the greatest scientist who ever lived, does not treat tuberculosis in that way. He huddles his patients in small rooms. This is approved treatment." (Dr. Hyndman, Cincinnati, O., speaks of the number of patients in a small room.) — Lancet Clinic in Koch's hospital. "It seems to me, doctor, that science could yet learn a little common sense. However, so long as you are attend- ing physician, I will obey orders." "On one condition, madam, I will allow you to enter your husband's room: Provided you wear a mask well padded with cotton wool. The wool strains out the tuber- cle bacilli." "Yes, doctor; thank you. I can then look at my dear husband." "Yes, madam; but you must refrain from speaking." "In regard to diet, madam, it matters little what you give your husband to eat, provided it be served in the proper manner." "Doctor, what do you mean by proper service?" "All food contains tubercle bacilli. The food and dishes should be perfectly clean and all milk sterilized and the dishes placed in the hot oven before and after use." "Doctor, do you allow butter to your patients?" "Butter in limitations is quite nourishing. It is used with the usual precautions." "What do you consider the best way to sterilize butter?' ' "Butter should be boiled. It is best eaten while hot through a sterilized tube. There is then no danger of in- fection." - 156- "Doctor, what shall I do in regard to my five dear children?" "Madam, I have not read the latest article by Count Von Blaunerhasselt, but I am of the opinion you ought to take unusual precautions." "Doctor, what would you think of sending them to their grandfather's? He lives on a farm far in the country. The children could have abundance of exercise in the open air and plenty of nourishing food." "Madam, if you value their lives as anything at all, you should do no such thing. To insure safety, your children should be placed in a germ-proof house and the T. R. treatment commenced at once." "Doctor, of course I have a mother's fear, but is the T. R. treatment dangerous?" "The danger from the T. R. treatment is now at a minimum, but of course in all cases there is danger." "Doctor, what is the object of T. R. treatment ?" "The primary object is to induce immunity." "May I ask one other question, doctor? What is meant by immunity ?" "There are two forms of immunity, madam. Immun- ity to tuberculosis and immunity to tubercle bacilli. It is of the former kind I now speak." "Doctor, do you mean by immunity to disease that one has the disease all the time ?" "No, madam; the very opposite. When one has im- munity to disease he never has the disease; he never has the disease so long as he is immune." "How long does immunity last, doctor?" "That depends. On an average something more than two hours." "Well, doctor, of course I am a woman, but this does not seem like immunity to disease, but rather a continuation of immunity." "As I was about to remark,, there is another form of immunity, viz., immunity to the tubercle bacillus. If one should be so immune that the germ could not enter his sys- —157— tern and grow, as this germ causes tuberculosis, the person so immune could not take the disease if he desired to do so." "Doctor, that is just the immunity I desire for my dear children; please explain." 1 'Virulent living tubercle bacilli are injected into healthy guinea pigs." "Doctor, you do not mean to so inject my children, do you?" "If left alone, in every case, these guinea pigs die of tuberculosis. ' i "Doctor, my children are not guinea pigs." "If these guinea pigs are injected with T. R. in time, the animals do not die of tuberculosis." "Doctor, you stated the guinea pigs are healthy. Why have them die at all?" 1 'As I said before, the germs of disease must be injected. ' ' "Doctor, as I said before, I am a woman. If my babe takes tuberculosis, are the germs of disease injected? Does not a condition of system allow the tubercle bacilli to enter? Does the T. R. treatment or injection eliminate the condition of system ? If not, does it or can it cure the dis- ease tuberculosis ? Doctor, please answer my question: Is there not always a condition of system that precedes the natural entrance of the growing tubercle bacillus ? If yes, theT. R. treatment cannot cure tuberculosis." Is tuberculosis contagious ? Yes, if you have the precedent state. No, if you have it not* -158- AN OUTLOOK. To one who travels the northern portion of our country and sees the boulders scattered here and there — some large, some small, all rounded as if by gradual attrition and con- tinuous movement — he is led to inquire, whence came these and what cause can be assigned ? It was the observation of these and similar data that led to the glacial theory, now generally adopted by scientific men. But what caused gla- ciers in this latitude? Evidently, it was change in climate, but in the attempt to explain this man is baffled at every step. Thus it often is in the elaboration of any theory. In science as in religion we see through a glass darkly, and yet we see. To the physician who has sat by the bedside and ministered to the wants of his patient in the dread disease tuberculosis, and witnessed a decline more apparent day by day, though steadily laboring to combat symptoms, he is led to inquire, why this dark blot on present civilization and just stigma to medical science? It is this and similar observations which has led to var- ious theories of the disease. One sees symptoms in tuber- culosis which are distinctly nervous, and he declares it a disease of the nervous system. Another, as he travels, be- holds germs or vegetable growths in all tuberculous tissue; to him these cause the disease; he at once formulates and advocates the germ theory. The writer plainly asserts he is not satisfied with either theory. Perhaps it is because he has one peculiar to him- self. Some people are built in this way. They are satis- fied with nothing unless it conforms to their ideas. Be this as it may, the writer gives his theory gratis, and the rea- sons are accompanied therewith. What more can be asked ? We speak plainly, it is not our purpose to unjustly judge —159— any theory, but to give as best we may our reasons for dis- carding the same. In doing this we do not arrogate all knowledge to ourselves, but we speak in order to be clearly understood* If the disease tuberculosis be of nervous origin on ac- count of the nervous symptoms, why not in the same breath declare it of muscular origin on account of the muscle wast- ing seen in every case ? It seems to the writer this would be just as consistent. One thing medical men should know: An attendant symptom is not necessarily a cause of disease. Every disease has symptoms peculiar to itself. Symptoms correctly observed render the diagnosis clear. But watch- ing symptoms is not determining the cause of disease. If germs alone truly cause tuberculosis, if the germ be ubiquitous, as most writers claim, why do not all take the disease ? Why do any escape ? If true, the result is mar- velous in the extreme. Herein is the greatest fallacy of the century. It is assumed that the plant tubercle bacillus is a parasite. It is a -parasite only in the sense of its growing on an an- imal already diseased. It never grows on the healthy animal. This was pointed out many years ago and has not been successfully refuted. Where are our living germ theorists ? Living germs are abundant. One thing must be evident to every unbiased mind: A plant cannot grow without a proper soil. Whence comes the soil ? The germ theorist assumes the tubercle bacillus grows indifferently in any soil. The writer thinks this is no such thing. In every case the soil must be -prepared. Ofttimes no doubt it is prepared unwittingly, but preparation, as the seed, alike is requisite. This all must learn. In many ways the soil is analogous to the soil of the farm or garden. As is well known, all soils are not alike productive. Some must be rendered fertile,- some need great care in preparation; some are but waiting for the seed. Each soil needs its particular care or attention. This the wise farmer learns from sad experience. So, in tuberculosis et us enlarge our borders. — 175 — DEEP BREATHING VS. TUBERCULOSIS. One-half of the earth's people are poorly fed. The reason is obvious. It is not that Mother Earth fails to yield her sixty or one hundred fold, but that the hand has been negligent or slothful in preparing the soil or planting the seed. Prosperity and effort are closely allied. "The hand of the diligent waxeth rich." Indolence has no incentive to labor. As a rule, famine stalks rampant in its fields. India, today, is an illustrious example. We note also famine and its twin sister, pestilence, thrive most among the heathen or half-civilized. Christian civilization knows nothing of fam- ine and little of pestilence from personal experience. They are practically driven from its borders. While we thus exalt civilization of this generation we must also note some of its faults or defects. Foremost among these is imperfect aeration of the blood. A vast majority of the civilized are consuming less oxygen than they should. The reasons are multifarious. One would naturally think the primary cause for this fault, defect or wrong consists in ignorance of the value of oxygen. The writer is inclined to think this view an in- correct one. The civilized are well informed. That it is not ignorance alone is certain from the fact that physiology is taught in all the public schools. The laws of the land allow or compel attendance at these schools, so no plea of ignorance can be raised. But why is it assumed there is imperfect aeration among the civilized ? What is aeration ? Aeration is ventilation of the blood as it passes on in the life current. Aeration takes place through the lung tissue. It naturally occurs in no other way. The lungs of man, as the gills of fish, per- mit the oxygen to enter the system. If the lung tissue be — 176 — imperfect, thickened, or in any way defective, aeration i^ incomplete, i. e., insufficient oxygen enters the system. Should one consume less food than is required by the system, or should the food be of imperfect quality, there is a starvation of the body. The same may be said of oxy- gen. One who takes in or consumes less oxygen than he should, either from ignorance, perversity or inability, the system must suffer. In one sense it is oxygen starvation or famine. Should one by deep breathing or inhalation take in more oxygen, or should one breathe a purer air and thereby receive a larger supply, every want in the system is met and the famine is declared off. This is what deep breathing does in certain states of the system. It removes the famine. But first, why is it thought there is imperfect aeration among the civilized? One-seventh of all deaths are due to consumption or phthisis pulmonalis alone. If we add to this number others who die of distinctly lung disease, as pneumonia, etc., the proportion seems abnormally large. No such proportion is seen among native tribes remote from civilization. To the writer, the reason seems obvious: They have a more perfect aeration. The perfect aeration of native tribes secures a practical immunity from lung disease. Civilization can show no such immunity. What does aeration accomplish ? As the oxygen enters the lung tissue it comes in contact with the venous blood and changes it to arterial. The impure blood is thereby rendered pure. The body, by this means, is kept in a healthy condition. This of itself is one of the essentials to long life. In order to have pure blood our food must be ample in quantity and quality. The oxygenation of the blood is just as essential. We look on famine-stricken India with hearts of pity and sorrow. Pity, there is so much suffering; sorrow, the people are so unwise and improvident. India could look on us with the same commiseration. The Americans and Europeans are so talented; they have every resource of art., science and literature, yet they are actually dying of starva- —177— tion— an oxygen famine. The East India men should help us. No doubt they would had they the zeal and knowledge. The zeal, perhaps, could be attained by a better food supply, the knowledge by the exercise of an acute observation, cer- tainly not by consulting standard authors, who tell us so much of disease germs and their action. What else does aeration of the bloo d accomplish? The food we eat sustains us or builds up our system as we digest or assimilate the same. Without digestion and assimilation there can be no true growth or strength added to our frame. To every student of physiology it is known that the lacteals empty the chyle, for the greater part, into the thoracic duct and from thence it is poured into the venous circulation. All chyle passes into this current. It here becomes subject to aeration in its round of the circulation. What does area- tion do to this new current which enters the channel for the first time ? It seems this is the last creative act, if we may so speak, in the formation of the new blood corpuscle. If so, it must be a very important one in the animal economy. New blood corpuscles are being formed, while at the same time the old are revivified. These two actions are con- stantly going on during aeration, are imperfectly performed during imperfect aeration, and stop when aeration ceases. It is seen that if every part of the human machinery be in- tact except aeration there is here found sufficient cause for im- purity of the blood and scantiness of the red blood corpuscles. We may give eliminatives, we may ingest a better food sup- ply, we may order / err urn redactum ad libitum, but we do not reach the true cause of the difficulty until we establish a more perfect aeration. Herein lies a secret in the treatment of many diseases. The disease tuberculosis, which is caused, we are told, by the germ tubercle bacillus, originates in this way. The first stage of tuberculosis is simply a faulty aeration. The bacillus enters secondarily — is never a cause of the disease. The faulty aeration may be due to many causes, but the re- sult is one and the same — tuberculosis sooner or later. The -remedy lies in the correction of this fault. It may take -178- years to teach this simple truth, but it will eventually be accepted, and we will look back at the amazing folly of hav- ing once thought an infinitesimal germ caused the serious disease tuberculosis. Colorado's burden will then be les- sened and the world will breathe freer and easier, with a purer blood supply and an enlightened conscience. It is this field of original research that has remained so long fallow that is destined to yield an abundant harvest on proper cul- tivation. Let us each, with God-fearing assiduity, sow and reap as best we may and patiently await our reward. It will assuredly come and that with thanksgiving and joy. We stated the quality and number of the red corpuscles is dependent on the perfection of aeration. Let us see if this be correct as to its practical workings. Take, for example, the ordinary student life at college. Of course, we are aware there is great difference in the student life of today and that of twenty years ago. There has been improvement on the social side, larger physical culture, more out-door exercise, etc. In fact, there has been a constant change, and that for the better. Yet, after all, student life is stu- dent life — a host of duties, incessant cramming, and for the studiously inclined, but little exercise. Many students are constantly tired, easily exhausted, nervous and irritable. What is lacking? A pure blood supply. Of this there can be no question. What is the remedy? Physical exercise in the open air, more perfect aeration of the blood or hema- tosis. In the writers judgment there is no question but that mental and physical training should be conjoined. All schools should be conducted on this basis. For further illustration take the ordinary housewife, who does, for the greater part, her own work. What is her life ? A constant round of duties in her household, never fully done. From early morn till latest eve it is constant, never-ceasing work. "A woman's work is never done." What are her cares? For family, home and self. Self usu- ally comes last. Her wants are many, but her greatest is pure oxygen in her own home, or time and opportunity for out-door exercise. She regards neither, but toils on , a poor —179— weak, anemic creature, and dies, most often, of phthisis pulmonalis. Could her untimely death have been avoided ? Is civilization in any wise to blame ? These are questions the twentieth century will be called to answer. Is not their consideration proper now ? But perchance the woman's sphere is not among the toiling millions. Her life is one of so-called social joy and gaiety. It is calls, balls, parties and receptions, of late hours, untimely meals of indigestibles, society's loud call for dress improper, etc. The life, ill-ventilation, etc., cause rising with languor and the noon day sun. Envy, jealousy and rivalry enter this life, but not more often than imperfeet oxygenation of the blood. Society has yet im- portant lessons to learn. Who would dare dictate to fashion ? May be the life is that of a wage earner, and who is not ? If so, it is so much work for so much remuneration. We enter not the vexed question whether the pay be suffi- cient for the labor. This is left to others. The question with us is, is the ventilation ample. Workmen are often crowded; the air space is insufficient and the room is dusty, or perhaps the lights are consuming too much oxygen. The remedy must meet the requirement. In all these cases systematic deep breathing in the open sir will overcome the difficulty if taken in time, provided the fault be remediable. It will benefit the patient even though the cause be continued. But the benefit in the latter case will not, of course, be permanent. Permanent benefit means freedom from tuberculosis. A question now arises: What faults are and are not remediable? If the fault be not enough oxygen in the room, if an irritant dust, gas or vapor, if a use of the upper air passages of the chest only, due to tight lacing or other cause removable, these are remediable. If by heredity we receive a lung tissue incapable of perfect aeration under the most favorable environment, if from continued exposure, taking cold or other cause we acquire a thickened lung tis- sue incapable of perfect aeration, these, of course, are not remediable. Deep breathing cannot alter permanently an hereditary or acquired lung tissue. Deep breathing calls into exercise the healthy lung tissue we possess, and aids — i8o— the patient in his effort to secure a better blood supply. This alone places him on a higher plane of health and enables him to more effectually resist the encroachments of disease. In other words, one who so acts keeps his system in a con- dition in which the germ tubercle bacillus does not enter and grow. He who so acts has a -perfect immunity to the dis- ease tuberculosis. The number of germs in the atmos- phere is of little moment provided there be a perfect aera- tion of the blood. Now please understand we do not advocate deep breath- ing as a cure-all for every disease. Systematic deep breathing, if the lung tissue be healthy, will insure a pure blood supply in so far as oxygenation of the same is con- cerned. Oxygenation of the blood, it will be found, is the essential element in the prevention of the precedent state, or first stage of tuberculosis. If true, how essential is per- fect aeration in the prevention of the disease. If true, the law of tuberculosis stands demonstrated: The death-rate from tuberculosis is in direct ratio to abeyance of atmos- pheric influence. Deep breathing does more than the oxygenation of the blood. As a preventive to taking cold or the ordinary catarrh it perhaps has no equal. Deep breathing, then, not only prevents tuberculosis directly, but it also prevents the very causes which lead to the same. How essential is deep breathing ! It seems to the writer this article is incomplete until a relation between deep breathing and physical exercise is shown. In one sense deep breathing is physical exercise. In another sense physical exercise is deep breathing. Yet it must be evident to all they are not one and the same. One may breathe deeply with little exercise. One may exer- cise violently yet breathe shallow. Physical exercise should be such as to cause perfect inhalation and exhalation. — 181- AN AHERICAN NEED. "A just observation and reflection upon men and things give wisdom; these are the books of learning seldom read." — Wm. Penn. The Americans as a people are well educated. Many things conduce to this end. Foremost among them a sys- tem of common schools prevail throughout the length and breadth of the land — the pride and joy of the nation. The children, when grown, have vivid recollections of these schools. Not only do they remember, but the habit of thought then and there formed follows them in after years. Early life is a period of inhibition; not only so, we also re- tain what we see or hear. The child at school may be compared to a sponge. Whatever is presented is readily absorbed, so that, squeeze whenever you will, the child or man gives out that he has absorbed or inhibited. This is a sequel to the present sys- tem. Whether it be regarded a fault or not, this much is certain: There is not that in us which tends to a vigorous growth or development. As writers and teachers we lack originality and force. The writer believes this a fault, one that should be corrected, or in some way avoided. It is our life. Wherein does the wrong or fault consist ? In this: We take in or assimilate as presented; we memorize and give out just as we receive. Such teaching or instruc- tion develops no originality. It is a parrot-like acquire- ment and delivery. Ages come and ages go and we roll on forever so. It is a similar system which has brought the Chinese empire where it is today. No people on this earth are bet- ter educated than the Chinese. Yet in true progress and clear ideas where are they ? One thousand years behind the age. May it never be so said of America. It is not the object to find fault with a system of edu- cation the like of which is not elsewhere to be seen— the rather to commend it. At the same same time it must be remembered that all human systems are faulty. To elimin- ate a fault is to improve the system. Do we desire improve- ment ? Why object to an- elimination ? As before stated, in early life the receptive faculties are open. This is as it should be. The child imitates, receives and retains. As yet there is no cultivation of the percep- tives. The child sees nothing except through his teachers. As he grows why not occasionally let him look for himself ? He passes from grade to grade, and, if studious, becomes an encyclopedia of information, yet destitute of originality — a mere book worm. As the best pastor endeavors to find work for each of his parishioners, and thus adds to or improves his talent, so the most capable teacher strives to develop in each pupil his powers of perception or originality. This is wise. Ency- clopedias are common. Book- worms are unnecessary. What the world wants is original thinkers for its advance- 1 ment. The sooner we discover this truth the better for mankind. No discovery is probable by one who has been educated under the present system. The system itself blinds one to original research. It is a continual memorizing of what others have passed on or determined. That the writer is not giving vent to an hallucination may be seen by observing the high school graduate as he leaves his alma mater. Watch him ! His unaided ability to secure a position and adaptability to gain a footing in the "struggle for existence" is child-like. He is a mere tyro. Place him on his feet, tell him what is to be done and how to do it, show him what is expected of him, and if he be faithful he learns more of practical wor th in one year than in the many years previously. The world's book of prac- tical suggestion and infor?nation is now o-pen to him for the first time. Is he educated to read this book ? W& ihiuk not. -i8 3 - The same may be said of the ordinary college graduate. Note the length of time before he finds a place adapted to his abilities. When out of school he is like a landsman at sea. Perhaps he begins with some menial employment much to his distaste, if none^other offer. By diligence he rises step by step and from his chaos of information he discovers there is little available at present. The bent of inclination, or more often the solicitations of friends, determines his vo- cation. All may go well. Very often everything goes ill, or it is rough sailing from the start, and the voyage proves uneventful. The great trouble is we are made too dependent on some one else. Teachers are not always present. There are some things we must observe for ourselves, else we do not know. Birds and flowers and trees, etc., do not grow with names stamped on them. To be familiar with these objects we must learn them from nature in nature's school. So in science; science of today is not the science of yesterday or tomorrow. It is changing. He who reads science truly must walk as in the day, with both eyes open, recognizing all men, -paying deference to none. He alone can read wisely. "A just observation and reflection upon men and things give wisdom; these are the books of learning seldom read." Give us more self-reliance and greater originality; these are potent factors in the world's evolution. After the classical course in the schools comes the fit- ting of oneself for professional life — a great w T ork. It is said the major part of our great men are college bred. This at best, is saying but little, for all of our children must have more or less of college training. If, then, w T e have distin- guished men at all they must of necessity be from this class. The question under consideration is, do our strictly college-bred men show marked traits for original research ? Are they distinguished along the lines of acute observation ? Do they not work in channels or grooves in which they have — 184— been taught? Do they not hold and reverence the authori- ties ? Are they not, as a rule, inferior in wisdom to the so- called self-made men? Our greatest .artists have ever copied from nature. Why should we, the students of nature, ever be following the scholastic method ? Let us think wisely, but let us think for ourselves, re- membering there are "Sermons in stones, books in running brooks and good in everything." -185- THE DAWNING Within memory of the present writer a health officer declared one dying of consumption should not be carried in a public conveyance unless the casket be hermetically sealed. Reason: The danger from germs is so great the public de- mands precaution and protection. Germs, in some localities, are yet considered dangerous — dangerous in that their true action or condition of growth is not clearly understood. We must live and learn. Thanks to an enlightened public sentiment, the above order is obselete. Other orders will be obselete ere long. The light is gently breaking, and soon we will behold the sun in his effulgence. The writer thinks he will bring heal- ing in his wings. Give us the light ! For the past tw T o decades we, as a people, have been harassed by the announcement that milk and its products — cheese and butter — are full of tubercle bacilli. We have also, during the same period, been studiously taught that as tubercle bacilli cause tuberculosis, these products are dan- gerous and should be inspected. A government inspector, as in Germany, has been urged. They say the people should be taxed and microscopists should pass sentence on all milk products placed upon the market. In this way tuberculosis could be controlled. In the meantime, until such inspection, we are advised to avoid cheese, boil butter and sterilize the milk, some even going so far as to counsel the eating of butter while hot through an aseptic tube. The writer, in his weak way, at various times has de- nounced these statements as fallacious. In the first place, he argues that tubercle bacilli do not primarily cause tuber- culosis. Tuberculosis is a constitutional disease, is based on law and the bacilli enter secondarily. The constitutional disease allows the natural entrance and growth of the -i86— germ. On this topic the author challenges controversy. If tuberculosis be a constitutional disease, the disease preceding the germ's growth, milk is a diseased product before the entrance of the growing germ, therefore, kill- ing the germ by sterilization would not render it a perfect milk. This was shown by the writer in 1894, {vide Tran- sactions Ohio State Medical Society.) If the milk be imperfect, milk products are also imper- fect, and no microscopist could detect this imperfection by the presence or absence of tubercle bacilli in said product. Microscopical inspection is therefore a useless expense. We pay taxes enough in this direction already. As stated, the writer has attempted to clear the way for microscopical entities. The replies have not been numer- ous; in truth, as a rule writers have stood aloof. Is there a reason why ? From the hills of New Hampshire we receive the following: DANGER FROM MILK OVER-ESTIMATED. "Experiments as well as observations made in the last few years lead us to believe that tuberculosis is much less often communicated to man through milk than was former- ly supposed." — New Hampshire Sanitary Bulletin, January 1900. A closer observation, we feel assured, will lead to the conclusion that tuberculosis is not conveyed in this way at all, only under certain conditions. These will be spoken of later on. But who are making these experiments and observations and what is their intrinsic worth ! The professors of the United States agricultural experimental stations are largely doing the work. The reports are of value according to the ability, honesty and common sense of the ones making them. Honesty we naturally expect. Some men are down-right liars. Common sense and ability, like twin sisters, walk hand in hand. Sometimes they are found alone, but only for short periods of time. They soon come together. They think so much of each other that they are close companions; nothing can separate. So far as we can ascertain, these ir en, for the major part, are germ theorists. For convenience, we divide them into theorists of the first and second waters. Theorists of the first water believe the germ -per se is all in all. Prof. Robt. Koch and his con- geners belong to this class. Men of this stamp believe germs are veritable Napoleons, carrying devastation, disease and death. Theorists of the second water believe there are germs and germicides; also a few other things worthy of notice. Dr. Russell, of Glasgow, Scotland, and Prof. Rus- sell, of the Wisconsin station, are men of this class. They believe germs have a mission, but it is inferior to the mis- sion of the being they infest. In other words, _, men are superior to microbes. It is a common impression that first- water men are graduates cf German schools, while second-water men have not crossed the North Atlantic. This is a mistake. Many first-water men are found who never crossed their state line, while some second- water men have visited many cities of Europe, and vice versa. Where one has traveled is of little worth. What does he know? This is what the world is "asking. This it will ultimately find. One may deceive himself forever. He can deceive the vast intelligence of mankind but for a short time. Deception is short lived. From the Storrs Agricultural Experiment Station of Connecticut, eleventh annual report, we find experiments were made by feeding eight calves with milk from tubercu- lous cows, and that without infecting the former. These calves were fed for periods varying from three months to sixteen months without developing the disease. The report is closed in brief, from which we extract the following sen- sible words: "We kmfw comparatively little regarding the ■conditions which favor the spread and development of tub- erculosis among animals or man.''' Evidently, the above was penned by a germ theorist of the second water. The second water theorist knows but little in his own estimation; the first-water theorist knows it all. When one rises to the admission he knows but little, he is in position to take the first step to obtain more.; when ©ne knows it all there is no incentive. He is practically dead and only needs burial. That little is known, as yet, regarding the condition s which favor the spread and development of tuberculosis among animals, may be seen by consulting Bulletin 108, June, 1899, issued by the experiment station located at Wooster, O. Ohio as a state is in many regards a leading one. The presumption is our men at Wooster are as com- petent as others. Why not ? "The herd of cattle at this station was established in 1894, by the purchase of a bull and two or three cows, each of the Jersey, Guernsey, etc. . . . At the time these purchases were made the idea was prevalent that the tuber- culin test might be injurious to the health of the animal. . For this reason the test was not insisted upon, etc., etc. On the station farm they were, of course, given good care, etc. All the increase was retained and by the spring of 1897 there were about eighty animals in the herd, all apparently in perfect health except two — a short horn cow and a Jersey bull, which had begun to show evidences of disease; the cow by rapid loss of flesh and the bull by the growth in the throat of a visible lump, which caused diffi- culty in breathing. At the beginning of June both of these animals were killed, after having been subjected to the tub- erculin test. The cow was found to be in the last stages of generalized tuberculosis, and the lump in the bull's throat was found to be due to the same disease. A supply of tub- erculin was then procured and in December and January further tests were made, and on June 8, 1898, fifteen cattle were slaughtered." — An Outbreak of Bovine Tuberculosis at this Station, p. 295. Then follow temperature before «and after these injec- tions, and the result as found after death — a very interesting report. These gentlemen should be congratulated. But the writer is not satisfied, in that the report is incomplete. It is incomplete in that the same number of animals were not chosen by the tuberculin test and placed under similar con- ditions. We would then have two lists of animals, one — 189— chosen by general appearance or inspection and one by the tuberculin test. Should the first lot develop tuberculosis we could say, as in this case, it is lack of the tuberculin test in selection. Should the second, "after the test, develop tub- erculosis, what could we say ? Either the test is inefficient or there is other cause of tuberculosis. Which would it be ? The writer asserts that after the tuberculin test tuber- culosis will develop, though more slowly. Why? In an article (Lancet-Clinic, November 20, 1897,) the writer held these conclusions: (a) Tuberculin determines the presence of growing bacilli. (b) Tuberculin has no value in diagnosis. (c) Tuberculin has no certain value in differentiation of first stage. (d) Tuberculin is sometimes dangerous. The writer holds these conclusions tenable. But our method of experimentation would be along a different line. We claim the precedent state is the first stage of the disease tuberculosis; that this state is caused by suspension of at- mospheric influence and is based on law; that suspension takes place from within and from without. Our questions for answer would be as follows: 1 . Does suspension of atmospheric influence cause a condition of system that allows the tuberele bacilli a natural entrance and growth ? Take a healthy animal and subject it to this test. Answer, yes or no. 2 . Is there more than one method of suspension ? Experiment on an animal. Answer, yes or no, 3. Is there an anatomical difference in the lung tissue of health and of heredity, or of acquired influence ? Sub- ject the lung tissue of each to rigid microscopical examina- tion or other scientific test. Answer, yes or no. 4. Is there a test, chemical, microscopical or other- wise, which will determine the difference in the blood cf health and that of suspension of atmospheric influence ? Has science a delicate test ? Apply this test to the livirg animal. Answer, yes or no. When these experiments have been made and correctly answered the law of tuberculosis will read as follows: The death-rate from tuberculosis is in direct ratio to abeyance of atmospheric influence, 290— MATHEflATICS IN MEDICINE. In my boyhood days I taught a winter school in the village of R . On entering the school building early one morning I found written on the blackboard the following: x }y *z x y =* z The value of z, please? A question at once entered my mind. Who wants a solution ? Several weeks later I learned a Mr. , who had taught in the village , desired one. Algebra is used but little in medicine, yet the writer thinks its introduction would lead to more accuracy in defi- nition, solve many hard problems and clear up some points- now obscure. In illustration, take the word heredity. What is meant by heredity ? The author defines it a prenatal inheritance. Whatever one receives in bone, blood, muscle, etc., prior to birth is by heredity. Let us see if this be true. Suppose one or both parents have a constitutional disease. Does the definition hold ? If not there is a mathematical inaccuracy. If true, there is hered- ity in every distinctly blood disease, etc. We quote from "Tuberculosis or Consumption" as follows: ^ You have a son to send to college. You call before you five leading clinicians in this state and put to each the test question : What factor is heredity in tuberculosis ? Listen to the an - swersr Nothing, little, much, a great deal, all. What arises in your mfctd ? One of two things— either these teachers are deceiving you or else they do not understand the busi- ness they profess. If/w can instruct exceft they who know?''' But, replies, a germ theorist, if tuberculosis be caused fay a germ,, which we have every reason to believe; if the growing germ be not transmitted,, as experiments seem to i —I9i— show, what matters it whether heredity be much or little ? Let us see: "It would seem much easier to formulate a co- hesive and rational theory of the propogation of tubercular disease by infection than to account for it by heredity." (Ohio Agricultural Experiment Station, 1899, Bulletin 108, page 364.) The writer thinks this statement manifestly unfair. Remember, it is a public document, paid for by the great State of Ohio. The present writer has no motive other than the advancement of medical science. He has a right to ask fairness. In what does the unfairness consist ? In the ambiguous word heredity. Does heredity mean [nothing, little, much, a great deal, all? Much depends on the an- swer. The majority of germ theorists claim heredity is nothing. In place of heredity put nothing, and then read: "It would seem easier, etc., to formulate, etc., by infection than to account for it by nothing.' * Not only would it seem easier but it would be easier. Of this the ^ writer feels certain. Who claims heredity is all ? Perhaps, all told, about five persons in the United States. To whom, then, is the committee of this experiment station talking ? To these five. What does the great majority of the medical profes- sion hold? That heredity is a factor in tuberculosis — a variable factor. In some cases more, in other cases less. Refer to history. We will attempt to explain this later. Now look at the unfairness of the above statement in the light of mathematics. To compare a factor or part with an entity or whole as to the formation of a theory. Mani- festly unfair ! One thing should be required of all public servants, viz., accuracy of statement, mathematics in defi- nition. Says the same authority on next page (365): "In dis- cussing the question of heredity we should keep clearly in mind the biological meaning of the term," Exactly. This is just what the germ theorist does not do. The germ theorist claims the germ grows indifferently in any soil, i. e. , the germ tubercle bacillus is the cause of tuberculosis. The — 192 — writer says not so. A soil must be prepared, i. e. y the soil must precede the growing germ . The germ theorist says that heredity is practically zero. The spread of the disease is from the germ alone. The writer says not so. Heredity is a factor. A soil may be transmitted. This soil aids in spread of disease. What is the order of the biologist ? Soil, plant, growth or fruitage. Who keeps the biological mean- ing most clearly? Mathematics in statement is required. Why is heredity a variable factor ? Simply because it does not occur in two cases just alike. I^et me illustrate. A father has tuberculosis; his partner in life is in good health; heredity in the child is one factor. Both parents are in good health; heredity in offspring of these parents is another factor. Both parents have tuberculosis; the child in this case is still another factor. The mother has tuber- culosis, the father is in good health; the offspring are other factors. And so on ad libitum in as many conditions as the parents may be found. Again, the parents' occupation, environment, etc., cause a variable condition of blood due to perfect or imper- fect aeration, and this continued in the parents and trans- mitted to an offspring cause variation in heredity as a factor. The great body of physicians in America are as honest and as competent as any physicians on the face of this earth. In saying heredity is a factor in tuberculosis they express a great truth. It is a factor. But we must look yet further. Heredity is not the cause of tuberculosis. The cause is suspension of atmospheric influence. Heredity as a factor aids this cause in the extension of the disease. Moral: In the prevention of tuberculosis heredity must be regarded in connection with suspension. A question is now presented to the germ theorist, viz.: Why the diversity of opinion, past and present, in regard to heredity if the germ theory be true ? In heredity what is transmitted ? If there be transmission at all there must be an entity. In order to understand this rightly, one must first clear- ly comprehend the law of tuberculosis. What does this law —19 teach or show ? In every case of suspension from whatever cause, there is first an impurity of the blood due to imper- fect aeration. This, if continued, leads to a condition of tissue favorable to the growth of tubercle bacilli. The tubercle bacilli ma}' be ubiquitous, but the} 7 are not omnis- cient. They grow, but they grow as all plant life — in a soil prepared. Now take this truth and use it in connection with hered- ity. What is the entity transmitted in heredity ? A pre- pared soil. We have, then, in heredity an identical condi- tion as in suspension at the first. Suspension creates a soil and heredity transmits a soil and they (the soil) are one and the same. Illustration: Mrs. A. has poor ventilation in her home. She becomes pregnant. During the months of gestation the imperfect aeration continues and it induces an impurity of the blood and a condition of the system or tissue favora- ble to the growth of the tubercle bacilli. The fetus receives the same blood and the same condition of tissue. Is this clear? This is heredity in the child. Should tubercle bacilli be found growing in the mother they may sometimes be found growing in the child. In either case, the mother or child alike allow the growth. Or, perhaps better, let the illustration be taken from life. Mrs.T., of E., has tuberculosis. She becomes preg- nant, and in due time is delivered. (I often wonder if abor- tion in some of these cases would not be justifiable.) The mother having suspension, there is suspension in the child, for, according to the author, in every case of tuberculosis there is suspension. Here, then, we have a babe ready for the growth of tubercle bacilli. In some few recorded cases the bacillus is found growing at birth. Dr. Jacobi, of Xew York, mentions such a case. Dr. Russell, of Glasgow, says: "These cases have an academic interest," thereby acknowl- edging their authenticity. The author thinks they have a greater interest than this. They have a world-wide inter- est. They prove a soil may be transmitted by heredity alone. Yet there are men in high places who deny to hered- -194— ity a value, and that before large classes. What astounding effrontery in the light of observation, reason and common sense. We now hasten to discuss another phase of this ques- tion. When a soil is induced by heredity, can it ever be changed back to its original condition? That depends, as in suspension, assuming there be simply a blood change or slight change in the tissue — yes. If the change be to dis- organization — no. Destroyed tissue cannot be restored. Again, should there be disorganization with immense num- bers of tubercle bacilli, as there usually is, all effort to re- store health is in vain. The patient dies. Should enough sound lung tissue remain to insure fairly perfect aeration, under favorable conditions, health may be restored, though not normal. In what way may this change for the better be brought about ? Just reflect one moment. What causes the dis- eased condition? Suspension of atmospheric .influence. What removes the condition? Removal of suspension. The remedy is a simple one: Breathe pure air. Illustration: We stated Mrs. T., of E., is delivered of a child. What is its condition ? One of suspension. The writer stated plainly to the parents the method to pursue. Remove the child at once from the/breast, feed it cow's milk and let it have abundance of pure air. The mother said no — "If I die let the child die with me." Dr. W., of R., is called. He approves my opinion. The mother still says "No." An uncle, Dr. C, of C, is called, and he, holding the same belief, takes the mother to his home and leaves the child under the writer's supervision. In three or four months the mother is covered with the clods of the valley, but that child, today a man grown, is in perfect health. At the time of removal it was thought by the trio of physi- cians that the child would live but a few days. It had high temperature, colliquative sweats and hurried respiration. This history is but a counterpart of hundreds of others seen in every civilized land. Do all receive equally favora- ble results ? The writer thinks not. —195— Let us now return to our analysis of bulletin 108, same page. "The fact that the child of tuberculous parents de- velops tuberculosis is by no means conclusive evidence that it has inherited the disease in the sense that it may have inherited physical conformation or mental characteristics." The writer confesses he does not clearly understand what the author of the above means. That his own view on this most important topic be clearly understood, the writer again quotes from ' 'Tuberculosis or Consumption:" "Children of consumptives \ though the environment be changed at birth die of this disease among other healthy children born of other far ents" Example: Mr. B. marries Miss T. Result of union, one child. Mr. B.'s family history is unique. Of the en- tire family, nine in number, consisting of grandparents, children and grandchildren, all die of tuberculosis, except one child of three, of diphtheria. Miss T. is of good family history, but is delicate. Knowing th£ above history, the child is taken and reared among other healthy children, yet dies of tuberculosis, aged twelve; the writer being the last attending physician. It seems to the author that in this case an entity was transmitted. Who can determine ? Another question bearing on the above now comes to view. Is physical conformation or mental characteristic transmitted ? Common observation shows that it certainly is. This child looks like her father. That child acts like his mother, etc. A likeness, similarity or entity is here seen. To be more explicit, is the entity of facial expression, etc., as seen in heredity, one and the same as the entity of a prepared soil by suspension ? It is not. In the former case it seems to be the result of a natural law or unfolding, whereas in the latter it is the result of a law violation or suspension. Each is an entity, and each comes under the head of heredity, but neither, so far as known, is controlled by a germ. This may appear strange, but "truth is strang- er than fiction." And now for a bit of experience. "The experience at — i go — this station with tuberculosis in swine, given on another page, gives a forcible illustration of the manner in which the disease may even skip a generation, to reappear in full force in the next and yet not come under the law of heredity as above defined." Benjamin Franklin was pre-eminently a practical man. He said to England, in 1776, that the proper way to eat a, large cake is to commence at the edge. The above is a large cake, and we propose to take Franklin's advice. Our nibbling is only at the edge. If the law of tuberculosis be true — and we think it is, ideally, at least — we can skip not only one generation, but five or six generations in succes- sion — ad libitum — and reinstate the disease in any genera- tion in less than eight weeks. This may also seem strange, but this in mathematics is called a corollary. "Again, there is a possibility of prenatal infection from either parent, previously referred to, which would be quite a different matter from constitutional heredity." This is the same old story of the germ theorist. Infection without a soil. How could there be "prenatal infection?" Can a plant grow without a soil ? If there be growth there must be soil — ask any biologist. If there be prenatal soil, this is heredity — the condition of growth. We now give the algebra of the germ theorist. We wish to be strictly fair. a - Health. b - The tubercle bacilli. c - Tuberculosis. The formula reads as follows: a ~ b = c. I^et us examine. Mr. B., what is your age? Twenty- five. Are you in perfect health ? Never better; just took out a policy for twenty thousand dollars; examined by three physicians and all say first-class risk. Please step this way one moment, Mr. B., I want to examine your sputum. A microscopical examination is made. Tubercle bacilli are found. Mr. B., did you eat butter for breakfast ? Yes, sir. Please examine the butter. Tubercle bacilli are found. —197— Mr. B., where have you been this morning? Walking in the open air. Please examine the air. Tubercle bacilli are found. Let us examine the formula: a + b '- c, i. e. y health -J- tubercle bacilli = tuberculosis. (Mathemat- ics don't lie.) This man has got tuberculosis. Bring in tuberculin and let us make a test. If there be a reaction he has got the disease without doubt. Tuberculin confirms. Ladies and gentlemen of the medical profession, this is medical science as taught today. Millions of our fellow- beings are hastening to eternity. Is it not time to call a halt? Let us proceed. "It is true that either of these forms of transmission of the disease given would be in one sense a hereditary transmission, but it would be transmission of infective material, not of actual disease nor of diathesis. The difference may at first sight appear to be hair-splitting, but, in fact, this difference is of fundamental importance," etc. The above is rather a singular statement. Please ob- serve—it is hereditary transmission, yet it is not hereditary transmission. It seems like hair splitting, yet it is of fun- damental importance. To the writer it appears like — it either rains or it don't rain, for it is very evident if it don't rain it must rain. We now open a field for controversy. "Because there can be no hope of overcoming this dread scourge until the fatalistic idea that it is a constitutional disease can be dis- placed by a clear conception of its contagious character." The writer thinks if we wait until "the fatalistic idea that it is a constitutional disease can be displaced' ' we will wait until Mother Earth lays by for re-pairs and receives a new axle-tree. In our judgment the constitutional will remain. But we leave this for the future to determine and talk of other things at this time. If the view herein be clearly unde rstood or correctly interpreted, it is seen an attempt is made to show a law in tuberculosis — an inviolable law; that heredity is a factor — 19» — aiding this law in an extension of the disease; that all dis- ease of this nature of whatever character is governed by this law. THE LAW OF SUSPENSION, The first stage in each case of tuberculosis is one of suspension. This creates a condition of tissue which allows the growth of tubercle bacilli. The tubercle bacilli do not cause the disease, but in many cases render it more fatal — fatal in that they cannot be removed — as a rule, they con- tinue to grow; fatal in that their growth consumes the air which should be taken up by the system; fatal in that their growth renders the lung tissue incapable of perfect aera- tion, etc. If in the stage of suspension before a growth takes place or while there is yet a feeble growth, perfect aeration be established or re-established — according to this law — the disease disappears and health is restored. In other words, if a perfect being — meaning by this one free from heredity as a factor — maintain a perfect aeration there can be no tuberculosis. Tuberculosis is, therefore, a disease of ill- ventilation or imperfect aeration. What, then, is the alge- braic formula for tuberculosis in the various stages of the disease ? a - Health. b = Suspension. c - Heredity. d - The tubercle bacilli. e - Tuberculosis. e' - more fatal. e" - most fatal. a -f b - e (formula i) i. e., health with suspension added means tuberculosis. Or transpose b: a - e — b (formula 2) i.