INTRODUCTOllY LECTURE TO A COURSE OF LECTURES UPON COMPARATIVE AXAT031Y, AND THE DISEASES OF DO^ilESTIC ANIMALS, DELIVERED J^'OVEMBER 3, 1813 BY JA3IES MEASE, M. D. SrXRETART TO THE PHILADELPHIA SOCIETY FOR PROMOTING AGRICULTURE, MEM- BER OF THE AMERICAN PHILOSOPHICAL SOCIETY, AND HONORARY 3IEMBER OF THE BATH AND WEST OF ENGLAND SOCIETY. i PHILADELPHIA : PRINTED BY LYDIA R. BAILEY, No. 10, NORTH ALLEY. 181 i. AKeaS€- Digitized by the Internet Archive in 2015 1 / https://archive.org/details/introductorylect01nneas TO «■ ROBERTS VAUX, AND REUBEN HAINES, AND THE GENTLEMEN WHO ATTENDED HIS FIRST COURSE OF LECTURES, COMP.IEATIVE Jl^ATOMr, AND THE mSE^SES OF DOMESTIC JimMJlLS, THIS INTRODUCTORY LECTURE IS DEDICATED, BY THE AUTHOR PMlad. Jliigust 10 , 1814 , At a stated meeting of tlie Philadelphia Society for pro- moting Agriculture, July 12tli, 1814, the following resolu- tion was on motion unanimously passed. , The society having been long impressed with the import- ance of veterinary knowledge, and having offered a premi- xim for the best essay thereon, are Avitli great satisfaction informed of the merit of a course of lectures, delivered last winter, by Dr. Mease, on “ comparative anatomy and the diseases of domestic animals;” whereupon resolved. That Dr. Mease he requested by the president to permit the introductory lecture, on the subject mentioned, to he print- ed in the third volume of the Memoirs of the Society. Belmont, July 14, 1814. Sir, Permit me to request a compliance with the xvishes of the Society, expressed in the enclosed resolution, hy your publish- ing your lecture, and thereby contributing to one of the great objects our society have long had in view ; — the encouraging every endeavour to promulgate and promote vetmnary hnoiv- ledge. I am, very truly, yours, Richard Peters. Dr. James Mease. INTRODUCTOIiY LECTURE TO A COURSE OF LECTURES UPON COIMPARATIVE ANA rOMY, AND THE DISEASES OF DOMESTIC ANIMxULS. BY JAMES MEASE, M. D. nELIVERED J\i'OVEMBER o, 1813. / Gentlemen, A conviction of the great necessity at present of a course of lectures upon Comparative Anatomy, and the Diseases of Domestic Animals, has induced me to undertake to de- liver them. I had indeed contemplated a course on the last subject, several years since, but was prevented from com- mencing it, by circumstances that no longer exist. The dif- fusion of knowledge upon the subject of my intended course, although at all times desirable, from mere motives of huma- nity, as connected with the means of increasing the comfort of a class of animals over which Providence has made us masters, who labour for us, feed, and clothe us ; is particu- larly important, if we reflect upon the value of some of those animals at the present time, when a laudable spirit of im- provement induces agricultural gentlemen to stock their farms at a considerable expense, with foreign breeds, or to take great pains in originating new stock at home, for the purpose of increasing the quantity and quality of flesh, milk, or fleece ; and when the employment of a large body of ea- VOL. III. c On Comparalhe Jlnatomy, and the valrj is rendered necessary, by tlie war in winch the United States are en.qaged. — But independently of this latter consi- deration, which is of a public nature, and certainly of suffi- cient consequence to claim the notice of government ; if the noble animal, the horse, considered in a domestic view, were alone the object of our attention, the importance and high value set upon him, when his powers for either speed or drauglit, or the beauty of his form have been greatly im- proved, would he an inducement sufficiently great to autho- rise a course of instruction upon his structure, diseases, and the means of preserving his health. As it is very probable that a part of my hearers are en- tirely irnacquainted Avith the subject upon Avhich I am to lec- ture, and even with the meaning of the Avords “ Comparative •Inatomy,’’ it is due to the importance of this branch of knoAvledgc to explain them, to shoAv what attention the stu- dy has excited in the old Avorld, to enumerate the names of the distinguished characters Avho have cultivated it, and to lay before you the very great benefits derived from it, in elucidating the structure and functions of the human body, and explaining the doctrines of its physiology : in aiding the Painter, Sculptor, and Engraver, and lastly, to point out its intimate connexion Avith Veterinary Medicine. By the term “ Comparative Anatomy” is understood, the investisation of the structure of brute animats : and its ob- jects are to demonstrate the diversity that exists among si- milar organs, and analogous parts, and to compare them with one another, and Avith man. It is reasonable to suppose that this study must have at- tracted the attention of mankind in very early times. The slaughter of animals for food, the preparation of the offer- ings on the altar by the priest, and the custom of deducing auguries from the state of the entrails, would naturally lead to some knoAvledgc of the structure and appearances of the parts : Ave knoAV likcAvise, from the book of Exodus, that names Avere even attached to them, and the parts deelar- Diseases of Domestic tlnhnals. S ed to be clean, and unclean, are particularly designated. But Greece first distinguished itself among nations, in the study of anatomy, as a science, as it did in the study and practice of the fine arts ; and Horner,^ by the familiar use of several anatomical terms, and the mention of certain parts of the body, and their connexion with each other, shows that some knowledge of the structure of the human frame was then extant. Pythagoras, after an extensive tour to India and Egypt, brought to his native country, the knowledge on all subjects to be ac(|uired at that time, and of anatomy among others, and disseminated it among his countrymen, with great ai’dour. His pupils, Alcmeon and Empedocles, but more especially Democritus of Abdera, extended the fame of their master, and raised themselves to deserved emi- nence among the philosophers of that day. Upon the suppo- sition that all the disorders of the human body proceeded from bile, he endeavoured to discover its origin and course, and by the ardour of his pursuits, and consequent frequent seclusion from the public, laboured under the imputation of insanity, until the sage Hippocrates, who was sent to visit him, discovered his retreat, and while he undeceived his fel- low citizens, with respect to his mental derangement, did ample justice to his industry and merits. Aris-totle, however, was the first scientific anatomist : he enjoyed particular advantages under the patronage of his pupil, Alexander the Great, who granted him a very large sum of money, to purchase animals for dissection, and to de- fray the expenses attending his studies. He did honour to the munificence of his royal patron, by his attention to, and improvement of the subject ; his regular anatomical works have been lost, but he has given much comparative anatomy in the first part of his treatise on animals, and he has form- ed an anatomical nomenclature, which is in part still receiv- ed. Without dwelling on the labours of Diodes of Caiy stus, and of Praxagoras of Cos, I shall pass on to inention the i On Compamlive Jhiatomy, find the, successors of Aristotle, viz. Erasistratus his grandson, and Ilerophilus, avIio having been protected and employed by the Ptolemies, sustained the character of the school of Alexan- dria so Avell, that, during their lives, and for a long time after, it continued tlie chief place of resort for students, from all nations. About the year 160 of the Christian account, Galen, a name familiar to the whole world, settled at Home, and con- tributed very largely to the advaneemcat of medical science generally, and particularly of anatomy, by his talents, in- dustry in experiments and dissections, and by collecting to- gether all that had been previously Avritten on the subject by the Greek teachers.* After his days Ave have no account of any addition having been made to the previous knoAvledge, in either human or comparative anatomy, for a very long time. To this suspension of the labours of science, the de- cay and division of the Roman empire, in the close of the second century, greatly contributed j hut the finishing stroke to all liberal studies or mental improvement, in the Avestern parts of Europe, Avas given by the irruption of the Barbarian tribes of Germany and Scythia, first into Rome, in 410, un- der Alarie, and finally over the Avhole of Italy, Gaul, and Spain, at different times afterAvards, until the year 476, Avhen the Roman empire Avas finally extinguished in the West. A long interval of midnight darkness in science of every kind, succeeded in the Avestern parts of Europe. The Sara- cens Avere at length, in their turn, destined to be the rulers of the former seat of learning and of the liberal arts in the East, and for a long time they did little except destroy. The burn- ing of the library of Alexandria Avill forever remain a splen- did monument of their fanatic barbarity.* Their successors Avere fortunately better disposed, and encouraged the arts,** and after the subversion of the A^isigoths in Spain, Arabian learning Avas introduced by them into that country, (anno 710,) Avhere it maintained its ground^ and spread through Diseases of Domestic d^nimals. 5 western Europe, until the ajra Avlien the genuine spirit for improvement and for scienee began to appear in the world. A worse enemy to scienee than even the Saracens originally had been, succeeded in the Turks, who from their first de- scent on the great theatre of the M orld, from the mountain- ous regions of Taurus and Imaus, to the present day, have uniformly evinced a settled hostility to improvement and in- novation of any kind. In 1055 they pillaged Bagdad, and the ruin of that seat of splendor and of learning, was com- pleted by the Moguls in 1258. In the progress of their victo- ries, but not until after a long siege, the Turks became mas- ters of Constantinople, (the last remnant of the Roman em- pire,) in the year 1453, and thus became the unwilling instru- ments of the diffusion of learning and the arts throughout Eu- rope : for the philosophers who had made that city their place of residence, after having been driven from Rome, fled to the Italian states for protection, bringing w ith them their own works, and those of the Greek authors in their original dress, and fortunately found the people eager to receive the information they had to communicate ; and, what was of most consequence, the different rulers of the country w ere disposed to afford them all the protection and support they desired. This spirit for the liberal arts had been revived, in part, in consequence of the acquaintance which the cru- saders had made wdth Arabian learning, during their chi- valrous expeditions to the holy land ; and the means of gra- tifying it had been already obtained, by the discovery of the mode of making paper, in the eleventh century, and had been powerfully promoted by that of the precious art of printing, in the year 1445, which facilitated the multiplication of co- pies of books. Europe thus enriched and roused made some progress in medical literature, and in anatomy, but it w as slow ; the popular prejudices, nay the abhorrence against touching dead bodies, and much more against their patient examination, long continued in almost all countries except Italy, and the 6 On Comparative Anatomy ^ and the consequence was, that Italy was the country in which human and comparative anatomy was for a long time chiefly taught. Upon the general diffusion of the spirit of inquiry in Eu- rope, Avhich continued to take place, the study of human and comparative anatomy kept equal pace for nearly all those eminent men who attended to one branch, were zealous in the prosecution of the other. But the sixteenth century may be considered as the sera whence we must date the re- vival of anatomical knowledge in general ; during which, we find among others that might he mentioned, the names ofVcsalius, Fallopius, Eustachius, and Fahrieius,® promi- nent as teachers. The science was prosecuted with ad- ditional spirit in the succeeding century, after the doctrine of the circulation of the blood had been taught by Harvey in London ; and more especially after his publication of the great discovery in 1628, when a new field w'as opened, from which both branches of our subject derived important bene- fits, by the new stimulus to experiment which it excited, and by enabling medical men to illustrate many points, before inexplicable, relative to the animal economy. In the course of the 17th, and the early part of the 18th century, the world was favoured with the labours of Grew,® Willis,^ Ty- son,® Collins,® Lower,“ Keill, and others in England ; Pey- eiV^ in Switzerland ,• He Graaf,i^ Leew^enhoek,’® Blazius,!"* Swammerdam,'® Ruyscli,'® Steno, and others in Germany and the Netherlands ; Eudbeck'^ in Sweden ; and Bartho- iine'® in Denmark ; Bellini, Valisneri, Malphigi,'® and Redi, in Italy ; Casscrius,^® Perrault, G. J. Duvcrney,^' and others, in France, The collection of facts made by the foregoing anatomists w^as great, no complete system however was farmed, until about the middle and latter end of the last century, when the observations of preceding authors were arranged, and the science was prosecuted Avith ncAv ardour. We were then favoured with the discoveries of D’Auhen- ton,22 the friend and coadjutor of the Count de Buftbn, in his great Avork on natural history, and Vie D’Azyiy® in Liseases of Domestic dnimals. 7 France 5 Camper^^ and Sandifort, in Holland; Pallas, in Russia; the illustrious Haller, professor at Gottingen ; Scar- pa and Camparetti, in Italy. In England, we are indebted to William and John Hunter, Hewson, Home, M’Cartney, A. Cooper, Townson, Haigbton, Cruiksliank, and others, and in Scotland, to the two Miinros (1st and 2nd,) for the elucidation of the organs of various animals, and for very considerable additions to our stock of knowledge on the sub- ject. Lastly, Cuvier,^® of Paris, and Blumenbachj^e of Got- tingen, may justly be considered as the most eminent contri- butors to comparative anatomy, in modern times. It would be tedious to detail the particular animals and subjects, to the investigation and dissection of Avhich, these illustrious men devoted their attention ; it may be therefore only necessary to say, that scarcely any part of the animal creation, from the colossal elephant to the crawling cater- pillar, escaped their attention; and that from all of their la- bours, instruction of the most useful kind, and from some of them, of the most pleasing nature, has been derived. I shall now proceed to enumerate the advantages that have resulted to mankind from the prosecution of comparative anatomy. Every well read medical man, Avho, not content with knoAV- ing merely the present state of the science of medicine and the art of surgery, has investigated the progress of their improvement, must be acquainted Avith the essential services Avhieh have been rendered to both professions by comparative anatomy ; yet as some of my hearers are not expected to be informed on this subject, it is due to the study, and may not prove uninteresting to them, to give a short account of the benefits Avhich have resulted from it. 1. The study of comparative anatomy opens to the mind a source of the highest satisfaction and interest, and tends most poAverfully to give exalted ideas of the Avisdom of the Author of all existence. In the Avords of the eloquent Her- der, it « gives man a clew to liimself, which conducts him 8 On Comparaiive Jlnalomy, and the through the great labyrinth of living creation ; and if we can say of any method, that through it our understanding ventures to scrutinize the profound and comprehensive mind of God, it must be this.”^^ From a very slight knowledge of the structure of the human frame, the royal psalmist was enabled to exclaim, “ man is fearfully and wonderfully made,” and had he been acquainted with the structure of the inferior order of animals, he would have found in them additional sources of wonder and of praise, from contempla- ting the infinite variety of modes in which the same func- tions are performed in diflerent animals, and in tracing the contrivances and structure of the organs and general me- chanism of their frames, which are so nicely adapted to their diflerent economies and necessities, whether their residence he in air, in water, or on land. 2. In the early stages of society, this study materially promoted the knowledge of the structure of the human body : for owing to the invincible prejudices against human dis- sections, and the prevalence of the opinion that the handling of a dead body communicated a degree of moral pollution to the living, it was extremely difficult to procure human bo- dies for the purpose of examination, and injurious to the re- putation of medical men to dissect them even if procured. The ancient physicians therefore were under the necessity of drawing their inferences with respect to the anatomy of the human body, and the uses of its various organs, from brute animals ; and apes, probably from their external form more nearly than any other animal, resembling that of man, were the chief subjects of investigation; and we know from the disagreement of Galen's account of the structure of va- rious parts of the body, with what has been ascertained by anatomists in later times, and from recent dissections of those animals, that it was from them his descriptions were chiefly taken.28 3. Upon various questions of physiology, which from their nature could not be ascertained in the human subject, this Diseases of Domestk Anbntils. 9 study has rendered the most essential services. The deer, in the park of king Charles the first, with which he gene- rously furnished Dr. Harvey, served to make some progress in the discovery of the process of the evolution of the foetus^ a subject that has since been greatly elucidated byDe Graaf, Spalanzani, Dm Haighton,^® and Mr. Cruikshank.^ By experiments on other animals. Dr. Harvey also ascertained, beyond contradiction, the circulation of the blood through the body, and its rotatory motion by the heart arteries and veins, so as to make many complete circuits round the body in twenty hours.^^ 4. It is to comparative anatomy we owe the discovery of the lymphatic system, and the certainty of the use it was in- tende(l to perform in the human body. The otfiee of this ad- mirable and curious system of vessels, is to absorb and con- vey back to the blood, all the decayed parts of the human body, (even bone itself,) and all those thin, pellucid fluids, that wander from the course of the circulation, that they may undergo new preparations, or be thrown entirely out of tjie body : and in the intestines, they perform the important office of conveying the nutritious and watery part of the food into the system. Hence they arise from every organ of the body. An opinion may be formed of the active pow- er possessed by those apparently tender, and minute vessels, from considering the rapidity with which they transmit their contents : this has been satisfactorily "“ascertained by Mr. Cruikshank, to be at the rate of twenty feet in length, in one minute. His experiments were made upon dogs, and the well known facts of a peculiar smell in the urine, being perceived in less than one hour after eating asparagus and certain species of cabbage ; and the increase of urine in the same space of time, after drinking certain mineral waters, lead us to suppose that the activity of the laeteals in man, is equally great.^^ 5. It is to this study we owe the discoveries of the cele- brated Italian professor Spalanzani, Dr. Stevens, John Hun- von. III. d 10 On Comparative Analomij, and the ter, and others, on the digestion of food in the hnman sto- niaeh, and in many other animals, about Avhieh process vari- ous erroneous theories had been previously entertained. The consideration of this process, as conducted in animals, with an examination of the admirable organs for the purpose, will form a very interesting part of our course.^^ 6. “ Comparative anatomy becomes necessary in ascertain- ing the action of organs. All the functions have ceased long before the human body can be opened, and it is only in the inferior animals that we can presume to make experiments examining the movements of the different organs before the principle of life has escaped.” It is chiefly in this field of in- quiry, that Ave have obtained the correct knoAvledge Avhich Ave noAV possess, of many of the animal functions.^^ Nor can the supposition be admitted, that this study savours of cru- elty : every humane mind is shocked at the idea of wantonly giving pain to any animal ; but Avhen such pain is requisite to illustrate the animal physiology, the sacrifice is indispen- sable and justifiable. Without it, Ave might, in all probabi- lity, have been ignorant at this day of the sublime discovery of the circulation of the blood, and deprived of the impor- tant henefits resulting from it to mankind. 7. By comparing the internal organization of different animals, Ave are enabled to distinguish those parts which are common in the structure of every animal body, and essen- tially necessary for the performance of the vital functions j from such as are peculiar to certain animals, and exclusive- ly subservient to their necessities, economy, or enjoyment. Thus Avhen Ave find particular organs imperfectly developed in certain animals, or extraeted^^ in some, and naturally Avant- ing in a third, without any essential injury to life, Ave are then enabled to judge of the rank Avhicli these organs hold even in the human species : and by the circumstance of life being supported, and the functions of the body going on, after a cessation in the performance of certain functions, Ave are not only taught the propriety of attempting the sav- Diseases of Domestic Animats. 11 ing of life, under cireimistanees whieli Avitliout such knoAv- ledge Avould have been deemed impossible ; but we are indu- ced to admire the Avonderful kindness of Providence, in fur- nishing the system Avith resources, Avhich enables it to sur- vive after such serious privations, and outrages to the ani- mal economy. We had long knoAvn that in tlie operation for aneurism, Avhere a Avounded artery is taken up, and com- pletely divided at the elboAV, or in the thigh, the limb heloAV the part is supplied Avith blood by the inosculating branches given off from the larger artery, above the point of obstruc- tion j hut Mr. Astley Cooper, of London, has shoAvn us, that even the carotid, femoral, and brachial arteries of the dog, in Avhich the stoppage of circulation might naturally he supposed would he folIoAved by the death of the animal, may he tied Avith impunity ; nay, that the aorta of the same ani- mal may he tied and divided Avithout injury to the animal and hence Ave are taught the propriety of attempting the saving of a human life, by ligature, in ease of a Avound in the large arteries of the body, instead of amputating the limb. To the military surgeon, Avho is called upon suddenly to exert his skill, in eases of dreadful Avounds, the inferences to he draAvn from Mr. Cooper’s experiments are invaluable.®" 8. It Avas by the study of comparative anatomy that avc have ascertained the cause why orans, apes and monkeys cannot speak. J. J. Rousseau, Avith the strangest inconsist- ency, Avhile he laboured to perfect his system, by Avhieh hu- man reason and the human poAvers Avere to attain the high- est possible exaltation, absurdly Avished to degrade man by assimilating his nature to that of brutes, and asserting that those animals had originally been endoAved Avith the divine faculty of speech, but had lost it from disuse. Although the assertion or opinion Avas contradicted, by the negative fact, that no savage nation had been discovered without an artificial language, while herds of orans had been found, without any ; yet no public refutation had ever been made, of the absurdity of the opinion, until after the year 1 779, when 12 On Compavatire vlnatomy, and ilic the excellent professor Camper of Holland, by dissecting the organs of voice in orans, apes and monkeys, demonstra- ted from their situation and structure, that no modulation of the voice, resembling human speech, can be produced in those creatures, because the air passing through the inma Glottulis, (or top of the Avindpipe,) is lost in two ventricles, or hollow bags in the neck, causing it to sAvell, and out of which the air is forced back, without any voice or melody, into the throat and mouth, tlu'ough a slit or hole at the root of the epiglottis.^^ 9. It is essential to the study of natural history : for ana- tomical structure is the only true basis of a natural classifi- cation of the animal kingdom. It was owing to his not be- ing conversant Avith comparative anatomy, that the zoologi- cal arrangement of the celebrated Linnseus is so deficient, and to an opposite reason may be ascribed the admirable and comprehensive classification of the French naturalists. 10. An attention to this study has enabled us to explain the facts related by some travellers, the extraordinary na- ture of which had occasioned an unbelief in them, and the imputation of a disregard to truth. — I allude to the narra- tives of the surprising poAver of the camel to take in at one time a sufficient quantity of water to last four or five days, and thereby to become capable of inhabiting the parch- ing deserts of Arabia ; and of the practice of the people of a caravan, of opening those animals when they die, in order to obtain the water from their stomachs. — The ex- amination of the stomaeh of this useful animal, shoAvs hoAV it is enabled to retain the water, and that it is pure enough to be drank Avhen taken from his body, by men Avhose thirst is great.^® 11. But Avhile comparative anatomy enables us to do jus- tice to travellers, it also furnishes us with the means of putting to the test the truth of various stories of the vulgar, some Oi which have been unaccountably admitted by men of sciettce.'‘“ Such, among others that might be mentioned. Biseases of Boviestie Animals. lii is that of the siihniersion of swallows in rivers, creeks, or ponds, during the winter, which has long been implicitly believed.-’i 12. A knowledge of the principles of comparative anato- my are as essential to the landscape painter, sculptor and engraver, as the knowledge of the human anatomy is to the painter of mankind. An artist may indeed depict upon canvass an animal, which without an inscription under it, may he known to be of the species intended to be represented ; but unless he is acquainted with the relative and natural proportions and forms, which modern improvements have shown are connected with not only beauty of person but pro- fit, he will not reach that perfection in his portraits or deli- neations, nor produce that effect by his labours, which is at all times desirable. ItAvas this knoAAdedge that has render- ed the engraved figures of the horse, by Stubbs, so much and so justly admired, although done so many years since, (1766, London ;) and Avhich contributed greatly to the reputation of the painter Adrian Vandervelde,42 and a fcAv others ; and although a minute knowledge of the anatomy of all animals is not expected from an artist, yet an acquaintance with the structure and mechanism, peculiar to each, is essen- tially necessary to enable him to delineate the muscles, and their action in various positions of the body, and to prevent the commission of those gross absurdities we sometimes see in statues and paintings, such as a Avalking horse represented Avith two diametric opposite feet in an elevated position.'*^ 13. Comparative anatomy is as essential to the successful practice of veterinai'y medicine, as a knoAvledge of the struc- ture of the human body is to the cure of the diseases and accidents incident to mankind. It is OAving to a Avant of this knoAvledge of their structure, that our useful domestic animals are so mismanaged by farriers, and pretenders to animal medicine ; and that diseases, trivial in their nature, or that slight surgical cases often end in death, or lameness, On Cominiralive Jinatomy, and the li whicli might have been easily prevented by a scientific treat- ment. Tlie aid which comparative anatomy is capable of afford- ing to veterinary medicine, must be evident to every one who reflects a moment upon the subject. “"The veterinary art is a practical application of scientific principles, to the preservation of the health of domestic ani- mals, and to the cure of their diseases, in the same manner as the art of medicine applies to the health and preservation of man : and the science on which this art is grounded, and which it requires for its perfect exercise, comprises the na- tural history, anatomy, physiology, and pathology of those animals, together with such portions of the vegetable and mineral kingdoms as are connected with them, either in the way of aliment or remedy. “ To practice this art with certainty, it is necessary to make a special and accurate investigation of the economy of the animal itself, and to observe minutely the different effects that the different subjects of the materia medica might have upon it, and to repeat tlipse inquiries with the same exact- ness, for every animal that is the subject of the art ; and moreover, to superadd such knowledge of the human anato- my, as may be of use in the way of comparison.”^^ A plan of study like this, requires a leisure and education, far be- yond the capacities and circumstances of those to w hom the care of our animals has been hitherto abandoned, and yet such is the importance of the art, that a course of study as long and as circumstantial as that just detailed, is indispen- sable for those who w ould fully, fairly, and honourably en- gage in the exercise of it ; nay, from the inability of the sick animal to describe his feelings, and to point out the seat of his pain, his pathology must necessarily he uncertain, and consequently we might suppose, that a greater degree of judgment and penetration are requisite for the physician of animals than of mankind. What then must be the feelings Diseases of Domestic vlnimals. 15 of any humane mind, to have a favourite horse, which may have greatly contributed to our comfort, health or pleasure, committed to the care of the most ignorant smith or farriei*, whose stock of knowledge may consist in knowing how to ruin the poor animal’s foot, by bad shoeing, or in giving him when sick, the same drench from a horn, whether the dis- ease be pleurisy or colic ? This regret will necessarily con- tinue so long as veterinary medicine is not studied scientifi- cally, or until medical gentlemen cease to think it beneath their notice ; and I may add, until the owners of fine horses will by pecuniary rewards, encourage men of respectability and knowledge to engage in its practice. Further, it is a truth, that nature, amidst the infinite variety in structure, seems to have fashioned all the living creatures on our earth after one grand model of organization : this is more especi- ally the case with those composing the extensive class mam- malia, of which man is the head. The bones, the muscles, the vessels, the nerves, the or- gans that prepare and secrete the various fluids of the body, and those of the difierent senses, as of seeing, hearing, smell- ing and tasting, seem to be substantially the same, except as regards some difference in form, size and position, arising from the peculiar wants of each animal. The diseases of mankind and of some animals, particular- ly the horse, are moreover very similar. Independently of the various accidents requiring the aid of surgery, such as wounds and fractures of bones ; the horse is also subject to fever, pleurisy, dropsy in the brain, severe catarrh, violent colics, dysury or difficulty in staling, diabetes or a preterna- tural flow of urine, various kinds of worms, epilepsy, asthma, locked jaw, and other complaints ; with the locked jaw, ma ny horses are carried off in this city every year. The Goitre or swelled neck, which is so prevalent a com- plaint among the inhabitants of Switzerland, of Thibet, and other countries of the old world, and also in the new fron- tier settlements of the United States, attacks sheep and calvev 16 On Comparative Anatomy, and the in tliis country, and dogs in Switzerland according to Mr. Coxe. From my inquiries into this complaint, as it ex- ists in the United States, I have ascertained that it invaria- bly disappears when the land is well cultivated, and di*aincd. But the fact is far otherwise in the other quarters of the globe ; there, it seems to he indissolubly connected with the climate and soil. Calves are also subject to the croup or hives,''^ and dogs and hogs to inveterate cutaneous eruptions. Dr. Sims, president of the Medical Society of London, says he knows the mange in dogs and cats will give the itch, and that of two sorts, the one being evidently larger than the other and a friend of mine was alfeeted with a large pustule, similar to the chicken pock, from touching his face after handling an imported merino sheep, at the time the animal was aftected with the disease called by the French, claveaii, or sheep-pock. Poultry too have their peculiar diseases, as the gaps in fowls,-*? and dropsy in the craws of turkeys. If we consider the present state of animal medicine in this country, under its appellation of farriery, we see it in as de- plorable a situation, as was the aj-t of medicine, during the barbarous ages, when the gross ignorance of its professors brought disgrace upon the art itself, and when many disea- ses, which now yield readily to judicious treatment, raged without controul ; yet that the veterinary art, like human medicine, in tlie hands of a judicious person, is raised to re- spect, we may see by the example of ancient times, and by the present example of several nations of Europe. If we look into ancient histoi-y, we find that before the downfall of the iloman empire, which crushed in its ruins all arts and sciences, veterinary medicine was esteemed among the most important objects, and worthy the consideration of an en- quiring mind. Connected on the one hand with human me- dicine, and on the other with agriculture, it both enlarged tlie stock of human knoAvledge, and improved an important Diseases of Domesfic Animals. 17 brancli of rural eeononly.^^ The renerahle Hippocrates Avrotc a treatise upon the subject.— In Carthage, Mago com- posed an elaborate work on rural and veterinary medicine. — Columella, who lived about the fiftieth year of the Chris- tian account, devoted four hooks, out of twelve on husbandry in general, to veterinary medicine. Catoj Tai’ro, Pliny, and Vegetius, (A. C. 300,) also laboured to serve veterinary me- dicine. — Indeed I find from my researches on this subject, that the course of human and animal medicine proceeded to- gether, until they both fell at the irruption of ignorance and barbarity into Europe, in the third and fourth centuries but at the revival of knowledge, and of a spirit of inquiry, while the intrinsic value of the life of man animated those labours which have advanced human medicine to its present state of perfection, it was the undeserved lot of veterinary medicine to he excluded from the asylum of the sciences, and to he left to the undisturbed possession of the most illi- terate and obstinate of men. — To withdraw it from its obscu- rity, and to restore it to that rank among the arts and scien- ces which it was its right to hold, was a merit reserved to France. So long back as the beginning of the sixteenth centnry, Ruellius compiled by order of Francis the first, a large assemblage of veterinary matter, whicli he translated into Latin, and published in folio, in the most splendid style, at the expense of his king. Afterwards, the government of the same country, under Lewis the fourteenth, formed the first establishment for studying the diseases of animals ; and in the year 1762, a regular school was founded at Lyons, in France, for the study and improvement of veterinary sci- ence, with every convenience for that purpose •, apartments for dissections, with a botanic garden, and professors in clie- mistry and materia medica, and others to teach the anato- mical structure of animals in general ; w ith the nature and cure of the diseases incidental to them, that thereby tlie whole nation might be provided Avith skilful farriers.^® This shortly after gave rise to a similar one near Paris, and VOI. IIT. c On Comparalivc Analomy, and the lA at present veterinary schools are as regularly organized throughout France, as schools for arts and sciences. The ce- lebrated D’Aubenton, the friend of the count de Buffon, pre- sided over the school at Charenton, and afterwards at Eam- houillct, on the removal of the national farm to that place. All these establishments being directed by men of zeal and science, and set on foot and supported by government, gave a degree of respectability unknoAvn before to the study, and so completely removed all former prejudices against it, that it soon afterwards became very generally cultivated by peo- ple of education throughout the kingdom. The example set by France was soon followed in Vienna by Maria Theresa, and her successor Joseph the second ; by Denmark, Sweden, and Prussia ,* and last of all England. — The veterinary college was established in London in the year 1790 ; and 1500 pounds sterling are annually granted hy government for its support. No person is permitted to offer as a candidate for the post of veterinary surgeon in the ar- my, without attending a stated time, the lectures and demon- strations of the professor, and undergoing an examination, conducted by some of the most eminent medical and surgi- cal characters in London, who from patriotic motives take on themselves that trouble. The professor of the college is Edward Coleman, a regular bred surgeon. The Dublin so- ciety, which is liberally endoAved by the government of that country, and Avhich has done so much for the improvement of Ireland, has also established a veterinary professorshij), and a regular bred physician (Dr. Peel) gives lecture-s on the subject. It remains for this country, in which the spirit for im- provement in stock of every kind is so visibly inci’easing, and tlie value of which is enhanced by the high price and the growing demand for some of them j to follow those ex- amples and by advancing the art to a height as yet unat- tained, to make it amends for the neglect Ave have hitherto slioAvn it. Indeed I am persuaded that in a short time the Diseases of Domestic Animals. 19 public attention will be called to the subject, and that men of education will think it no derogation from their medical character, to become acquainted with the diseases of cattle, or to lend their aid in the removal of them when required j and thus rescue our useful animals from the unqualified hands to whose care they must otherwise, as at present, from necessity be committed. A distinction must be made between veterinary medicine and farriery. The first is founded upon science, whereas farriery disclaiming any connexion with science, proves itself a mere practice, habit or routine, and as it rests on nothing regular or solid, so it must ever be variable. The course of veterinary medicine and farriery are indeed the same, but with this difference, that the former condescends to admit a guide, while the latter prefers to ramble at risk and hazard. Were their objects any way different, farriery would have a plea for rejecting the assistance of veterinary science, found- ed on the peculiarity of its own object. But they are strict- ly the same, so that the only alternative might be in the su- perior excellence of the means by which it endeavours to ac- quire it. But we know that farriery pretends to ho such means, that its practice is a collection of prescriptions and operations, without rule or precision, communicable to any body, in the form of a pamphlet. With this view" of the subject, how is it possible that we can sacrifice so much of our common prudence, as to give to it any portion of that -confidence w hich medicine itself is only capable of exacting from us, in proportion as it exhibits a quite opposite cha- racter.™ Such being the facts Avith respect to the knowdedge re- quired for the veterinary practitioner, and such the distinc- tion betAveen veterinary science and farriery, let us inquire into the inducements and necessity that exist for acquiring the knoAvledge of this branch of the medical profession. 1. The importance of the subject. The argument derived from this source rests on the value 20 On Comparative Jinalomy, and the of cattle, as they are a source of public and private opulence; the means of our subsistence, and the instruments of our convenience and pleasure. This value, 1 repeat, is daily in- creasing, owing to the spirit for improvement now spreading through the United States, and to the high price of some stock, particularly line woolled sheep, the demand for which even in the case of peace, will rapidly increase, from the mere increase of population. 2. The veterinary science offers a new and respectable means of employment to its professors. It must be obvious, that to the medical practitioner in the country, the knowledge of the diseases of domestic animals will be tbe means of not only greatly extending the sphere of his utility, but his personal consideration, particularly with respect to the noble animal the horse, which always contributes so largely to our wants, wbieh augments our enjoyments, and preserves our health, and is on many oc- casions an object of particular interest, from the circum- stances of cost and individual merits, Will the young practitioner think that he derogates from his medical dig- nity by performing an act of humanity, and extending the sphere of his usefulness in any way connected with the ex- ercise of his profession, especially in one that has engaged the attention and labour of some of the most eminent men, both of ancient and modern time, in Europe ?— -AVill he de- rive no satisfaction— -nay more, will he not add to his medi- cal eclat, or obtain pecuniary recompense, from saving the life of a favourite racer of a sportsman, or the hackney of a wealthy invalid ? Will he not think himself well employed in setting the leg of a horse of the hunter breed, so valuable for cavalry, and the carriage, and which, although no longer able in consequence of the accident to shine in the field, may still propagate his valuable race ? 3. In the United States, an additional necessity for atten- tion to improvement in our knowledge of veterinary medicine arises not only from the fact of our ignorance of the sub- Diseases of Domestic Animals. 21 ject ; but of our stock being liable as well to the common dis- eases to Avhieh they are from their nature exposed in all countries, as to peculiarly fatal diseases, the origin of which is involved in great obscurity. In the states of South Carolina and Georgia, cattle brought from Europe, or from the interior, to the vicinity of the sea, are invariably attacked by a disease which is generally fatal. Cattle from the interior of the state of South Carolina, (but only a particular district,) so certainly disease all others with which they mix in their progress to the north, that I am told they are prohibited by the people of Virginia from passing through the state. The singularity of a fact attending the disease is, that the cattle alluded to have the power of in- fecting others witli which they associate, while they tliem- selves are in perfect health ohis I can assert from my own personal observation, in the year 1796. The particulars of this singular but fatal complaint I shall hereafter detail. Pennsylvania has to regret the loss of many thousand horses, by a disease which deserves no other name than yel- low fever. I allude to the “ yelloio xvaier,” the symptoms and method of cure of Avhich are totally different from the jaundice, yellows, or yellow water of Europe. This disease, I have reason to believe, is peculiar to North America.®* Europe furnishes no disease similar to the mortification in the limbs of the New England cattle nor to that peculi- ar salivation Avhich has Avithin the last tAventy years attack- ed our horses, from eating second crop grass, particularly red clover,®^ and Avhich from its debilitating effects, amounts to a disease. For the last four or fire months, a ncAv and very fatal disease has prevailed among the horses in the vi- cinity of Ncav BrunsAviek, Ncav Jersey. 4. It has already been shoAvn, that by means of compara- tiA'e anatomy Ave have ascertained the uses of various organs of the human body ; and I now can add, that by an attention to the diseases of brute animals, the folloAving advantages have also resulted to mankind. 22 On Comparative Anatomij, and the 1. We have been enabled to obtain precise ideas of the nature and seat of some serious diseases of the animal frame. ! Of the facts illustrative of this position, one of the most im- j portant to mankind is the knowledge of the cause of the lo- cal and general disease that sometimes succeeds the opera- tion of bleeding in the arm. — 'For a long time the inflamma- tion and suppuration beginning at the orifice made by the lancet, and the fever that ensued, were ascribed to a punc- ture of the tendon of the biceps muscle, or of the fascia of the arm, or of a nerve ; by others these symptoms were sup- posed to originate from a bad habit, or from the introduc- tion of some poison adhering to the lancet ; but that great benefactor to medical science and to surgery, the late John i Hunter, of London, having observed a similar accident to take place after the rough operation of bleeding horses in the neck, was led to ascribe the disease in both eases to the same cause, viz. the inflammation of the internal coat of the vein ; and repeated dissections of inflamed veins, in which | the operation had been performed, have proved the accura- cy of his opinion. By the elucidation of the disease in ques- tion, Mr. Hunter has made us acquainted with the true cause ^ and seat of a serious disease, and increased the obligations i he has laid the medical world under by his other improve- ments in surgery and medicine.** 2. We have been indebted to the brute creation for one of the greatest temporal blessings, ever conferred upon man- j kind by Providence, in the discovery, that by conveying from a small pustule on the teats of the udder of the cow, a par- ticle of matter, under the cuticle of the human subject, he was forever secured against that scourge of his existence, the small pox. If before this new source of happiness to mankind had been drawn from this useful animal, such an event as that just now mentioned, had been declared within the compass of possibility, the supposition would have been thought as improbable as that which I now venture to make, viz. that there is just reason to believe, as in the instance Diseases of Domeslie tAnimals. eye* here exhibited, the possibility that an incapacity of being I acted upon by the canine virus in both man and animals, may be produced by exciting in them a previous disease. In alluding to the disease sometimes produced by the bite of a rabid animal, I am sorry, very sorry to be obliged to declare, that it still continues to humble the pride of the me- dical profession. We know indeed its peculiarities and symp- toms, and I myself have contributed to elucidate its patbo- logyj but we also know its extreme fatality 5 and with regard to the means of cure, the learned and experienced physician is brought at once to the level of the most uninformed among the multitude ; for, gentlemen, the disease has never been cured, and to this day, we are obliged to remain the helpless spectators of our patient’s sulferings.’® But we must not despair ; for I cannot think that Provi- dence has determined to permit this disease to he forever in- curable, and can any more powerful argument be adduced for investigating the diseases of domestic animals, than the knowledge of this fact, that all of us are cvei’y day of our lives liable to the attack of an aAvful and incurable malady from one of them, and who is the gratcfisl companion, and faithful midnight defender of our bouses and property ? On this disease I shall deliver a particular lecture ; and although I will not assert that I can point out a mode of cure, yet it will still be useful to investigate its pathology, for truth is always elicited by discussion. 3. An attention to the diseases of domestic animals is more- over of infinite importance to the practitioner of medicine in another point of view : for by them we are led sometimes to anticipate fatal epidemics, and of course are provided with the means of guarding against them. Homer tells us, that the plague that spread among the troops at the siege of Troy with great fury, first made its appearance among dogs and cats. In the plague that ravaged the island of Egina, to the south of Athens, about sixty years before the Trojan war, and of which Ovid has given an affecting account/' the 2-i On Convparativc JLnalomy, and the disease also first invaded dogs, then sheep and oxen, and lastly mankinds The pestilence eindeinic among the cattle, in the year 576, at Rome, was succeeded the next year by a mortal plague.®* Dr. Sims of London, informs us, that the scarlet fever which prevailed with very great mortality in the city of Lon- don, in the year 1798, was preceded by a remarkable epide- mic among cats, which is said to have killed myriads of them. In the following year an epidemic prevailed among the hor- ses, which appeared to he a peripneumony, attended with a discharge from the nostrils like glanders. A similar mor- tality among cats prevailed in the months of May and June, in 1797, in Philadelphia, and destroyed thousands of them : and we all remember the pestilential fever that prevailed during the following autumn. Fish too, often experience the effects of a pestilential atmosphere,^ of which the history of the epidemics in 1793, 179i, and 1797, in our own country, afforded strong proofs.®® In other cases, epidemic diseases, or a general unhealthi* ness of the air, have been preceded or accompanied by a vast increase of insects and small animals. Of this, a number of instances might be mentioned, from Lord Bacon respecting tlie plague in London in 1666 ; from Diemerbroek on the same disease in Holland in 1635 and 1636 ; from Baddam, on the plague of Dantzick in 1709 ; and from the account of the epidemic at Bengal in 1771. During the fever at Plymouth, Massachusetts, in 1633, the woods were filled with innumerable large flies, of the size of bees, 6® and during the pestilential time in the United States, between 1792 and 1801, various other insects abound- ed in different parts.®^ In particular, during the year 1798, grasshoppers overspread the country ; and we know that that year Mas very unhealthy. In the year 1805 also, the grass Mas destroyed by them in the low counties of New Jersey; and the same year, such was the mortality in Salem county, that I M as informed the courts could not proceed in Diseases of Domestic Animals. 25 their business, owing to the death of many jurymen by malignant fevers. The same year tlie yellow fever prevail- ed in Philadelphia. Many more facts of a similar nature might be mentioned, were it necessary. In the prosecution of my course, it is my intention to adopt the following plan : 1. I shall demonstrate the structure of different animals. 2. Explain the use and functions of the several parts, and compare them with those of the human body. 3. Point out the causes, nature and symptoms of diseases in our domestic animals, w ith the method of cure. 4^. Give the natural history, operations and doses of me- dicines. From this plan it will he seen, that farriery, strictly so called, or what relates to the fashionable operations on a horse, makes no part of the course. By thus separating the scientific from the merely mechanical part, the veterinarian science will be at once put in a condition to go hand in hand with human medicine ; but it is proper to remark, that in respect to the noble animal just mentioned, the preservation of whose health is so essentially important to us, the proper method of shoeing shall be taught, and directions given for restoring to a natural state those hoofs which have been in- jured by a bad system having been previously followed ; with ample instructions how to preserve his health in all situa- tions in which he may be placed. vox. III. f NOTES TO THE INTRODUCTORY LECTURE. JV'*o/e 1. See the Iliad, book 5, verses 65 and 30i. Book 11, verse 5T-i : other passages might be referred to. J\'‘ofe 2. Galen was a native of Pergainus in Lesser Asia; and af- ter travelling wherever instruetion was to be obtained, settled at Rome. Although a pupil of the Alexandria sehool, he did not blindly adopt its dogmas. On the contrary, he thought and acted for himself; as a proof of which it may be men- tioned, that he disproved by a simple and obvious experi- ment, the opinion it had long entertained and taught, (viz. that the arteries carried air,) by laying bare a branch of one of them, in a living animal, and dividing it between two li- gatures. JVotc 3. This event, it is said, took place in the year 640 of Christ, and that for six months the Turks heated their numerous baths by the MSS collections of one thousand years. Tlie fact is not credited by M. Renaudot or Gibbon. The writer upon whose authority it is given, is Ahul Pharagius, “ and the solitary report of a stranger, who wrote at the end of 600 years, on the confines of Media, is overbalanced by the silence of two annalists of a more early date, both Christians, both natives of Egypt, and the most ancient of whom, Eu- tychius, has amply described the conquest of Alexandria.” Gibbon’s Decline, &c. chap. 51. Eutychius lived between ^''otes to InlroAuctonj Lecture. 27 the years 876 and 950. Abul Pharagius was a native of Malatia, and died in 1286, at Aleppo, primate of the East. His work (Historia Dynast.) was translated from the Ara- bic, by the learned Pococke, into Latin, 1659. JV’ofe 4. Under the auspices of Almanzur, the second caliph, and his son Abdallah, Bagdad arose and flourished in the East, (762) and at once became the residence of the successors of Mahomet, and for a long time the seat of all the learning in that quarter of the world. The exertions of the learned men of that day, however, were confined to translating an- cient Greek manuscripts : they made no dissections. Never- theless the spirit of inquiry was thus kept up, and to their translations did the western part of Europe OAve their ac- quaintance with the learning of the ancients. JN^ofe 5. AndrcAV Vesalius Avas born at Brussels about the year 1512 or 1514. He AA^as educated at Louvain, and studied anatomy at Paris, under Sylvius. In 1537 he Avas appointed professor at Padua, by the republic of Venice. Charles the fifth called him to be his physician, and he Avas also physician to Philip the second. He published his celebrated Avork, de Humaiii Corporis fahrica, in 1543, Avhen only about 30 years of age : in this he detected the anatomical errors of Galen, and proved that he had taken his descriptions from brutes. This service to truth raised him numerous enemies. He is said to have been forced to fly, or to banisli himself, in con- sequence of having opened the body of a Spanish nobleman, supposed to be dead, but Avhose heart he found beating. Other causes are ascribed for the act, but Avhatever Avas the motive, he set out to visit Jerusalem Avith Rimini, general of the Venetian army, and returning at the invitation of the senate of Venice, to fill the chair at Padua, he Avas ship- Avrecked, and died on the island of Zante, in 1564. Fallopius Avas born in 1490, and was a pupil of Vesalius, and aftcrAvards professor at Pisa, and at Padua, Avhere he as J\*otes to Introduclory Lecturt. died in 1563. Ilis works are contained in three volumes folio. He was deemed among the lirst physicians and ana- tomists of the age, and cultivated medicine and anatomy with great zeal. Eustaehius was contemporary with the two forinei', and taught at Rome. He was a zealous anatomist, and the pas- sage from the ear to the mouth is called after him, the Eu- stachian tube. Fahrieius Ah Aquapendente, (the preceptor of Dr. Har- vey,) was professor at Padua, which for nearly 200 years was the most respectable medical school on the continent of Europe. His works were collected and published in Latin, atLeipsic,hy professor llohn, in one volume folio, 1687, with numerous plates. Besides much human anatomy, he has treated largely of the organs of animals. 6 . Nehemiah Grew, an ingenious and learned physician, was the son of Mr. Obadiah Grew, minister in Coventry. Hav- ing been sent to a foreign university for some years, he re- turned, after taking the degree of doctor of physic, to Lon- don, and was admitted to fellowship in the college of physi- cians in 1680. He obtained extensive practice ; was elected a fellow of the royal society ; and on the death of Mr. Old- denburg, succeeded to the office of secretary ; in consequence of which he carried on the publication of the Philosophical Transactions for a considerable time. He also drew up a catalogue of the articles in the museum of the society, which he finished in folio, under the title of Museum Regalis So- cietatis. To this is generally appended a work entitled the « comparative anatomy of stomachs and guts,” being seve- ral lectures read before the royal society in 1676. The work however by which Grew is most deservedly celebrated, is his anatomy of plants, in which he has shown a wonderful degree of ingenuity. This work is accompanied by very nu- merous and well executed engravings, and may be consider- ed as one of the most curious performances of the seven JV\)f€S to Introductory Lecture. 29 teenth century. Another very celebrated publication of this author, is the Cosmologia Sacra, or “ a discourse of the uni- verse, as it is the creature and kingdom of God.” — This was chiefly composed to demonstrate the truth and excellence of the sacred writings. Dr. Grew died in 1711. Trans. Royal Soc. Loud. J^ew JLhrid. vol. 1. page 660. J\''ote 7. Thomas Willis was born in Wiltshire, in 1621, and died in 1675. He was an excellent anatomist, as he has proved in his Jlnatome Cerebri. He also wrote Pathologia Cerebri, and Be Anima Brutorum. His works Avere published in London, 1679, in Latin, and 1681, in English. 8 . Edward Tyson was a celebrated physician and anatomist of the seventeenth century, and a great contributor to the Philosophical Transactions, especially on subjects relative to natural history and comparative anatomy. He read lec- tures at Gresham college. Besides his numerous commu- nications to the royal society, he published the following works : Phocfena, or an anatomy of a porpus, 1680. Cari- gueya seu Marsupiale Amerieanum, or the anatomy of an opossum, dissected at Gresham college, 1698, (of Avhich an account is also inserted in the Philosophical Transactions.) The anatomy of a pigmy compared with a monkey, an ape, and man, 1699. Trans. Royal Soc. Loud. JVeio Mrid. vol. 2. page 448. JV'ote 9. Samuel Collins published “ a system of anatomy ofcthe bo- dy of man, beasts, birds, insects and plants,” 2 volumes folio, 1685, Avith numerous plates, accurately representing the parts described : there is as much comparative as human anatomy in the Avork. < JV'ote 10. Richard LoAver Avas one of the best anatomists of the se- venteenth century. He Avas educated at Oxford, took his degree of M. D. in that University, and exercised his pro- 30 ^"“otes lo Inlroduclovy Lecture. Icssioii there for some years ; but at length removed to Lon- don, where he got into extensive praetice. He and Dr. King appear to have been the first avIio performed the experiment of the transfusion of blood. Besides several papers inserted in the Philosophical Transactions, he wrote a treatise, Avhich procured him a great and deserved renown, de corde, item de motii et colore sanguinis ct chyli in eum transitu, 1669. Among other things in this treatise, he pointed out the difference between arterial and venous blood, proving that the florid colour of the arterial blood is derived from the air. Trans. Royal Soc. Land. JSTew Ahrid. vol. 1. p. 197. J\'ote 11. John Conrad Peyer, M. D. rendered important services to the anatomists of his day, by his Avork entitled “ Meryco- logia, sive de ruminantibus ct ruminationc commentarius.” Bazil, 1685. Js^ote 12. Rcgner de Graaf Avas born at Shoonhoven, in 16 il j he studied at Leyden under de le Boe Sylvius and Van Horne j but took his doctor’s degree at Angers, and practiced at Delft. He Avas the author of the folloAving anatomical trea- tises: De sued pancrcatici nalura, 166i>, and 1666 ; Devi- vorum organis generationi inservientibus, 1668 ; De miilk- rum organis generationi inservientibus, 1672 ; Defensio par- tium genitalium, 1675. These Avere collected into one 8vo volume, and reprinted after his death, under the title of Opera Omnia, Leyden, 1677. He died prematurely when only 32^ears of age, in consequence, as is supposed, of great uneasiness of mind, brought on by the Avarm disputes in Avhich he Avas involved Avith SAvammerdam. In his tract on the pancreatic juice, he gives an account of a very difficult ana- tomical experiment Avhich he performed on a living dog, opening the abdomen, and inserting a tube into the pancrea- tic duct, for the purpose of collecting the juice thereof; to Avhich he, like Sylvius, ascribed acid properties. By his other Avritings he thrcAV considerable light on the structure Xotes to Introductory Lecture. 31 and uses of the different parts belonging to the organs of ge- neration in both sexes. Trans. Royal Soc. JVexo Jlbrid. vol. ±, page 2ii. De Gi’aaf also rendered essential services to anatomy, by contriving convenient instruments for injecting vessels, the idea of which had however occurred before to others, and had even been carried into effect. JV’ote 13. Anthony Van Leewenhoek, so highly celebrated for his curious microscopical observations, was a Dutch gentleman, of Delft in Holland. He was born in the year 1632, and died in 1723, aged 91 years. Leewenhoek was not, properly speaking, a man of letters, hut from the extraordinary assi- duity with which he pursued his researches into the minuter parts of nature, and the striking novelty of the curious ob- servations which he published, his name is perhaps more frequently quoted by philosophers and naturalists, than that of any other writer of his time. This celebrated observer had the good fortune to live at a period, when the instru- ment by which he obtained bis fame, was yet in some de- gree in its infancy. He applied himself with unremitted care to the grinding and polishing into a state of perfection, the simple lens, as being the best calculated for accurate in- vestigation ; and less liable to those deceptions which a com- position of glasses sometimes occasions. So many, and so extraordinary were the discoveries of Leewenhoek, that he may be said to have brought into view a new world in sci- ence ; and such was the general truth and fidelity of his ob- servations and descriptions, and the respect paid to his com- munications, that he has been not unaptly complimented with the title of the Delphic Oracle, and yet he was not free from errors. Trans. Royal Soc. Land. JVew Mrid. vol. 2, page 66. His works were printed in Latin at Leyden, in 1722, and afterwards in Low Dutch and have been translated into English by Samuel Hoole, London, 1800. 32 Js*otes to Introdiictonj Lecture. J\''ote 14. Blazius published in 1681, a volume in quarto, on the ana- tomy of various animals, with plates, entitled Jlnatomia Jlni- maliumjiguris variis illustrata. He had previously publish- ed a smaller one in 1673, entitled Jlnatome Hominis, Bruto^ rimque variorum, and other works. dVote 15. John Swammerdam. This celebrated anatomist and natu- ral historian was horn at Amsterdam in 1637. His father Avas an apothecary in that city, and possessed a small cabi- net of natural curiosities, by the frequent survey of which his son acquired a taste for those pursuits, by Avhich he af- terwards rendered himself so conspicuous. He studied at Leyden, where he took the degree of doctor in medicine, in 1667, hut never engaged in the practice of physic, devoting himself wholly to anatomical and physiological inquiries, and to collecting and examinyig insects. Of this class of animated beings he investigated the generation, structure, and metamorphoses, with astonishing patience and assiduity, and described and elucidated the same in his admirable work entitled, « A general history of insects,” first published in the Butch language, in 1669, and afterAvards translated into Eng- lish. His Historia Ephemerse appeared in 1675. These and other observations, relative to the natural history of insects Avere collected into a folio volume, (Dutch and Latin,) print- ed at Leyden in 1737, under the title of Biblia Naturae, sive historia insectoriim. This edition Avas superintended by Bo- erhave, Avho Avrote the biograpMcal memoirs Avhich are pre- fixed to it j but the Latin translation was by Gaubius, pro- fessor of pathology at Leyden. Besides a tract on respira- tion, Swammerdam Avrote another anatomical Avork, entitled, Miraculmn J^aturcc scu uteri mutieris fabrica, published in 1672. He appears to have been the first who practiced the art of injecting the blood vessels Avith wax ; for his country- man and contemporary Ruysch learned this method of him. His collection of insects and other objects belonging to JS^otes to Introductory Lecture. natural history, forM liich tlie Grand Duke of Florence once offered him 12000 fforins, was sold for a very inconsiderable sum. I'cans. Royal Soc. Loud. JK'^ew Jlhrid. vol. l*]j. 190. Swammerdam first employed hot wax to inject into the blood vessels. J\''ote 16 . Frederick Ruysch was born at theHague in 163S, studied at Leyden, and settled at Amsterdam, on being appointed professor of anatomy there. He formed a fine collection of anatomical prcjiarations, and curiosities in natural histoi-y, Avhieh was purchased by Peter the Great, and sent to Peters- burgh. He died in 1731, aged 91 years. Ruysch excelled in the art of injecting the blood vessels, and in filling the ca- pillary vessels. He also employed maceration and erosion. He first discovered valves in the lymphatics, and contributed largely to the progress of anatomical knowledge by his la- bours. His Avorks make four volumes quarto, enriched with a great number of plales. jVote 17. Rudbeck Avas born in Sweden in 1630, Avas professor of physic in the university of Upsal, and founder of the botanic ganlen there. Xote 18. Thomas Bartholine Avas the son of Caspar Bartholine, (a man of universal erudition,) he ’arss Jt ffrst made professor of mathematics, at Copenhagen, bcif afterwards filled the anatomical and medical chair in that university. In this si- tuation he discovered the lymphatic vessels. He also traced the course of the thoracic duct in the human subject, con- firming and elucidating Pecquet’s description thereof. His anatomical and medical Avritings are very numerous. This celebrated man died in 1680, aged 6i years. Philos. Trans, abridged, vol. 1, p. 247. J^^oic 19. Mareellus Malphigi Avas born in tlie year 1628, near Bo- logna, Avhere he studied and graduated, M. D. in 1633. He J\'‘otc$ to Inlroduclorij Lcclure. 3i' Mas elected to the professorsliip of the theory of medicine in tliat university, in 1656, but soon afterwards accepted of a similar appointment at Pisa, which situation he resigned at the end of three years, as the air of that place was pre- judicial to his health. In 1662, he succeeded Castelli in the professorship of physic at Messina, where he remained four years, and then returned again to Bologna. Here he continued as a teacher of medicine in the highest repute, Iroin 1666 to 1691, when he was invited to Rome, and ap- pointed chief physician to Pope Innocent XII. He died at Rome of an apoplexy, in 1691. Malphigi’s labours have throAvn great light upon the structure and physiology of the human, brute, and vegetable creation ; as may be seen by consulting his Jlnatomc Plantarum, Epistolce AnatomicK, Exercitationes tAnatomicce, Dissertationes dc JJtero, de For- matione j)ulli in ovo, de honibyce, &c. These tracts were col- lected intotw'o folio volumes, printed in London in 1686, un- der the title of Malphigii opera Phijsica et Medica. And in 1697 a third folio volume appeared, containing his Opera Postliuma. In his anatomical investigations he resorted to Avhat in those days Avere iieAV methods ; viz. to maceration of the parts, injection of the vessels Avith coloured liquors, and the employment of magnifying glasses. By such means he Avas veiy successful in developing the intricate structure of some of the viscera in man and quadrupeds, as Avell as the minute fabric of insects and vegetables. He appears to have been the first Avho used the microscope for examining the circulation of the blood. Trans. Moyal Soc. Land. JTav ,*3.1). Tol. 1, p. 190. Francis Redi Avas born at Arezzo, in 1626 ; studied phy- sic at Pisa ; Avas appointed physician to Ferdinand II, and aftei'Avards to Cosmo III, for Avith the family of the Medici, literary and scientific merit led to preferment, and was sure of receiving its due tribute and rcAvard. After his death, in 1698, Cosmo caused a medal to be struck to perpetuate his name. Ilis letters (2 vols. 8vo) contain a variety of medi- JV"o{cs to Introductory Lecture. 35 eal cases and remarks, wUli observations on anatomy, natu- ral liistory, and experimental philosophy. His style is re- garded hy his countrymen as higlily classical. His works amount to 7 volumes 4to. Hutchinson, vol. 1, p. 429. JS'ole 20 . Casserins wrote Be voce uuditusquc organis historia ana- tomica. Paris, 1600, folio, with plates and cuts. J\"'otc 2H The title of one of Perrault’s Avorks is OEuvres diverses de Phisiqnc et de Meclianique, far Mess. C. & P. Perrault, (a Avork of the latter, on fountains, having been published with those of his brother Claude,) Leyden, 1622, 2 vols. ito. Claude Perrault also Avrote Memoires pour servir d Vhis- toire naturelle des aniinaux, 1676, folio. He Avas an excel- lent architect, and designed the superb entrance of the Lou- vre. lie died in 1687, aged 75. His life may be seen in Hutchinson’s Biographia Medica, Ijondon, 1799. G. J. Duverney, professor of anatomy, Paris. Haller says of him, ‘‘per sexaginta annos innumerabilia corpora incidit, ct a praxi etiam medica abstinuit, ut inter mortuos viveret ; multorum certe inventorum auctor, que aliis nominibus tri- buuntur.” Bibl. Anat. tom. 1, p. 626. Duverney Avas the human and comparative anatomical pioneer of the latter part of the J 7th, and beginning of the IStli centuries, Xole 22. D’Aubenton gave the anatomy of most of the animals, Avhose natural history Avas described by Buffon. Two edi- tions AA ere originally published of Buffon’s Avork one in ito. and another in 12mo. — But later French and English editions have omitted the anatomical parts. Mote 23. Yic D’Azyr, the son-in-laAV of D’Aubenton, Avas a very able human and comparative anatomist ; he compiled the excellent system of comparative anatomy inserted in the Mouvellc Encyclopedie Methodique in Avhich the anatomy of each animal is given separately ,• and published many papers 36 ^^oles lo Introductory Lecture. on the subject in the Memoirs of the French Academy. The anatomy of each animal is given separately, whereas Cuvier and Blumenbach treat the subject according to the organs and functions of the body. J^otc 24. An excellent account of Camper may he found in the New Edinburgh Encyclopsedia, published by Edward Parker, Philadelphia. Me 25. Cuvier’s work is entitled Lecons D’Anatoinie Comparee ; in 5 vols. 8vo. and a 6th of plates, Paris, 1805. The two first vols. have been translated in Loudon by Mr. Ross under the direction of IMr. McCartney, lecturer on comparative anatomy. A larger work by Cuvier is shortly expected on the same subject. JVote 26. Blumenbaeh’s work is in one vol. 8vo. and forms an ex- cellent compend of the science. It is well translated by Mr. Lawrence of London. The transactions of the royal society of London contain a great number of papers on com- parative anatomy by various persons : a list of which is given in Dr. Thompson’s excellent and, entertaining “ His- tory of the Royal Society from its institution to the end of the ±8th century, London, 1812,” p. 112. The subjects be- ing scientifically classed, by Dr. Thompson, a reference to it will save much unnecessary labour in searching the volu- minous work of the society for a paper on comparative anatomy, or any other subject that he may wish to investi- gate. See also the article Comparative Anatomy” in the Philadelphia edition of the New Edinburgh Encyclopfcdia for a list of authors and papers on our subject. JVote 27. The title of Herder’s profound work is “ Outlines of the philosophy of the history of man, by John Godfrey Herder.” An English translation was published by T. Churchill, Lon- don, 1800, 4to. JVo/es to InlrodHclory Lecture. jyote 28. Anatomists might have reasonably concluded that Galen’s anatomical descriptions had been taken from brutes ; be- cause, although he says, he had dissected many of the latter, yet he makes no mention of having examined human bodies : we know also that he expressly advises physicians to prac- tice the dissections of apes and monkeys, and not to lose the opportunity of dissecting human subjects if by chance, the German war, or any other accident, they should find one ; and had Galen ever dissected a human body, his vanity Avhich is so conspicuous in his writings would not have permitted him to conceal the fact. Vesalius first discovered that Galen’s description of the human body Avas formed from the dissection of brutes, by comparing his descriptions Avith the actual structure of the parts as laid open by the knife, and for this service to medicine and to truth he excited the en- mity of all the medical professors, Avho had been promulgat- ing Galen’s mistatements, as truths. J\'ofes 29, so. Trans. Royal Soe. London, 1797. A^ofe 31. Harvey’s account of his discovery is entitled “ Exercitatio Anatomica de Cordis et sanguinis motu.” It is an extraordi- nary circumstance that the circulation of the blood through the body, should not have been discovei ed before the time of Harvey, considering that the fact (although not founded on experiment) is plainly asserted by Plato, Avhose Avritings had been so long familiar to the learned Avorld. “ The heart, says he, is the centre or knot of the blood vessels : tlie spring or fountain of the blood Avhieh is carried impetuously round; the blood is the pabulum, or food of the flesh : and for the purpose of nourishment, the body is laid out into canals, like those Avhich are draAvn through gardens, that the blood may he conveyed, as from a fountain to every part of the pervi- ous body.” 3S J^otes to Introductory Lecture. Hippocrates also speaks of the “ vessels communicating Avith each other, and of the hlood undergoing a kind of flux and reflux from and to the heart like the ebbing and flowing of the sea,” and even mentions the throbbing of the temporal arteries, as an evidence of the fact. Galen also had (as I have before said,) showed that the arteries contained blood as well as the veins, by the simple experiment of dividing a branch between two ligatures in a living subject, and thus disproved the opinion of the Alexandria school, that they merely contained air. The lesser circulation, or that through the lungs, had been ascertained by Servetus a Spanish phy- sician, and by Columbus the pupil of Vesalius, and was known to other eminent men ; and Coesalpinus an Italian even men- tions the communication between the arteries and veins at their extremities, and speaks of the valves of the arteries and auricles as capable of preventing the return of the blood, but still it is apparent from other parts of his writings that he had no consistent idea of their use or of the circulation. Further, the early discevery of the valves of the heart, and those placed at the mouths of the large arteries which had been made by Erasistratus ; of those in the veins of the ex- tremities by Sylvius, as mentioned by Stephanus, and the dis- covery of similar valves in the veins of the arm by Fabricius of Padua, the preceptor of Harvey, it Avould seem might at once have led to the belief of the existence of a similar organization in the veins of other parts of the body, and to a knowledge of their use in preventing the return of the blood, to the extremities, and to the deduction of its having been previously carried from the heart by tlie arteries. It was this organization of the veins that furnished Harvey with one of the strongest arguments in favour of his sublime dis- covery. Finally, says Dr. Hunter, “ the obvious phtenomena in bleeding animals to death, the different effects of ligatures on different vessels, the practice of surgery with regard to bleeding and blood vessels, the action of the heart when ex- posed to view in living bodies, all these so evidently proclaim ^'"otcs to Introductory Lecture. 33 the circulation, tliat there seems to have been nothing more required for making the discovery than laying aside gross prejudices, and considering fairly some obvious truths.”* Yet anatomists continued until the time of Harvey to assert that the liver was the source of blood, and that from it, the vital fluid was distributed to other parts of the body. For an account of the opposition made to Dr. Harvey by the envious part of his contemporaries, and of the injurious effects which this sublime discovery had upon the temporal prosperity of its author, the reader is referred to Dr. Rush’s volume of Introductory Lectures, a work which ought to be in the possession of every gentleman, and of every professor of divinity, medicine or law. — The life of Harvey may be found in Hutchinson’s Biograpliia IMedica. JV'otc 32. See Cruikshank’s anatomy of the absorbent vessels, p. 30, London, 1790. The history of the absorbents is curious and extremely Interesting. — Erasistratus the grand son of Aris- totle had certainly discovered these vessels in the intestines of a kid, but he thought they were arteries and agreeably to the opinion of the Alexandrian school of which he was a pupil, he supposed they contained air like other vessels of the same nature. These vessels are also hinted at by Hip- pocrates, and Galen, but their real use was ascertained by Azellius of Cremona in 1622, who in dissecting first a dog, and afterwards other quadrupeds, observed vessels contain- ing a milky fluid to commence from the intestines •, but though he traced them to a cluster of glands which he called pan- creas, yet because he also found a few similar vessels on the liver he supposed that viscus to be their final place of termi- nation. The result of the labour of Azellius was published with coloured plates in 1627, after the death of the author, and the year before Harvey’s work on the circulation came Tntrodvictoiy Lecture, p. 43. 40 vYoles lo Inlvodiiclory Lcclure. out : for many years both these works excited great interest and the anatomists of all Europe were zealous in verifying their discoveries, and in testing their remarks hy the dissec- tion of living animals. At length Pecquet of Paris saw the chyle actually floAving into the heart of a living dog in a regular stream, and traced the source of this fluid to the com- mon receptacle of the thoracic duct. He published his ac- count in 1651 : Eustachius before had seen this duct, hut did not knoAV the real use of it : he called it vena sine parL Van Horne a Dutch professor laid claim to the merit of the same discovery the following year. Eustachius had a century be- fore discovered the same vessels in a horse, hut he was igno- rant of their use in the economy of the animal, or of their origin. The honour of ascertaining both points was reserv- ed for Pecquet. The discovery of another set of absorbents, Avhich arise from all the cavities of animal bodies soon fol- lowed hy the dissection of dogs, viz. in 1651 or 1652. These were called lymphatics from the pellucid nature of their con- tents, and were found toeiulAvith the laeteals in the thoracic trunk. In later times, the same system of vessels Avas found hy various anatomists in all other animals that Avere examined, of both land and water, and in the human brain hy Mascagni of Italy, from Avhosc dissections a series of the most elegant plates have been published. The merit of discovery of the lymphatics in other parts of the body, besides the intestines, Avas due to Bartholine and Rudbeck, Avho Avere contempora- ries in the 17th century. The priority of time hoAvever hy a fcAV months seems to belong to Rudbeck, although Bartho- line first published his account of the lymphatics. 33. Dr. EdAvard Stevens of St. Croix : his experiments are contained in his inaugural dissertation on digestion, Edin- burgh, 1777 : a very good abstract of them may he found in Smellie’s philosophy of natural history. Dr. Stevens made some of liis experiments upon an Hungarian. JS^otes to Introductory Lecture. 41 JS'*i)te 34. New Edinburgh Encyclopsedia, article comparative anato- my. In this way the vermicular and peristaltic motion of the bowels — the respiration of birds, and the action of their gizzards, &c. &c. were ascertained. JS^ote 35. The spleen has been extracted from dogs and other animals without any injury, and even from man : as Haller shows by numerous authorities : Phys. tom. 6, p. 421, 4to, Lugdun. Batav. 1764. Mr. Shipton cut out two fingers length of the ilium of a dog, without injury to him. Phil. Trans. No. 283. Dr. Musgrave cut out the cpecum of a bitch, without any in- jury. Phil. Trans. No. 151. The late Dr. Jones of Phila- delphia cut off a portion of the pancreas of a man, that pro- truded from a wound, and he did well. J\Tote 36. One dog lived « for more than twelve months, with the two carotids, the two femorals, and one brachial artery ob- literated.” The vessels were tied in succession, after the wounds of a previous operation had healed. The dog whose aorta was tied, lived two years, and was then killed ; and the body being injected, the anastomosing vessels were beau- tifully seen. Med. and Chirurg. Trans. London, vol. 2. ^^ote 37. The saving of life by taking up the vessels of the neck, or the large vessels of the extremities, when they are diseased or wounded, is a modern improvement in surgery. In form- er times, death in the one ease, and the loss of the limb in the other, was tlie fate of the sufferer. Mr. John Bell of Edinburgh, took up the posterior iliac artery, in consequence of its division, by the points of a long pair of scissars, “ at the place over the sciatic notch, Avhere it comes out from the pelvis j” it was tied exactly where it turns over the bone, and the man was cured, and walked stoutly.” Surgery, 4to, vol. 1, p. 423. h vox,. III. ^''oles to Introductory Lecture. vZ. Mr. Abcrnethy of London, first tied the external iliae ar- tery above Poupart’s ligament, Avliieh operation he perform- ed in a case of femoral aneurism. His first and second at- tempts were unsuccessful, owing to the desperate nature of one case, and an unusual occurrence in the other. Mr. A. afterwards was happy in saving two lives by it.* Mr. Freer and Mr. Tomlinson of Birmingham, performed the same ope- ration with success, each onee.f Dr. Dorsey also perform- ed it in the Pennsylvania Hospital, in 1811, successfully.:]: The patient walked on the twentieth day. Mr. Astley Cooper of London, has also tied tlie carotid artery for aneu- rism, in two cases, the first, in 1895, was in the right caro- tid ; death took place from “ an inflammation of the aneu- rismal sac and parts adjacent, by which the size of the tu- mour became increased so as to press on the pharynx, and prevent deglutition, and upon the larynx, so as to excite vio- lent fits of coughing, and ultimately impede respiration.” In the second case, in 1808, the disease was in the internal carotid, and was cured. See Medieo-Chirurgical Trans, vol, 1, pages 1 and 222. London, 1809. Dr. Post of New York, has also within the last year successfully operated in New York for aneurism in the carotid artery.:]; See also Mr. Cooper’s account of the dissection of a limb, in which the operation for poplitial aneurism had been performed, in the Medieo-Chirurgical Transactions, vol. 2, London, 1812. eYofe 38. Professor Camper rendered most important services both to human and comparative anatomy. His account of the dis- section of apes, monkeys and ourans outang is inserted in the Trans. Royal Soc. London, for 1779 — vol. 69, and is entitled * Surgical observations on the constitutional origin and treatment of local diseases, and on Aneurisms. London, 1809. f Freer on Aneurism. Birmingham, 1807, 41o. Dorset’s Surgery, vol. 2. J\'otes to Introdiiclory Leeliu'e. 43 On the organs of speech of the ouran outang.” But as these animals cannot speak, the expression should have been voice and not “ speech.” — Dr. Tyson of London Avho Avas himself an accurate dissector, had published in 1699 “ ourang outang, or the anatomy of a pigmy compared Avith a monkey, an ape and man,” 4to. Avithout discovering the difference be- tween their organs of speech and voice. Albinus, Martini and even D’Aubenton are also silent on the striking construc- tion of this organ in apes. The merit of professor Camper Avas therefore the greater, for it unraA'elled the mystery of their incapacity of speaking, although possessed of organs, (as Avas supposed) equally Avell adapted to the end, as those of man. Mr. White confirms professor Camper’s statement, and exhibited a preparation of the membranous bag of the monkey to the Manchester Society. Account ol' the regu- lar gradation of man, by C. White, p. 27 — London 1799. There can be no doubt of the confirmation, nor any difficul- ty in accounting from it, for the Avant of speech in ourans, apes, &c. Lord Monthoddo labours hard to prove, Avith Rousseau, the humanity of the ouran outang, and accounts for the difference between the result of Tyson’s and Camper’s dissections of ourans, by the circumstance of the first having examined one from Angola, and the other those from Borneo. See Origin and Progress of Language, vol. 1. p. 344: and Ancient Metaphysics, vol. 3. p. 44. No anatomist or natural historian Avho grounds his distinctions of animals upon anatomy will attend to this argument. tMofc 39. D’Auhenton, by the dissection of a camel for Buffon’s na- tural history, had many years since actually found a consi- derable quantity of Avater in the cells of the stpmach, though the animal had been dead ten days. The Avater Avas clear, almost insipid, and drinkable. He therefore assents to the assertion of travellers, that camels are killed for the Avater in their stomachs. Perrault, Avho dissected a camel in 1676, Mem. de I’Acad. de Seien. tom. 3, Avas of the same opinion, JN'*otes to Introductory Lecture. but Mr. Home has put tlie question beyond all doubt, by the dissection of a camel in London, in the year 1806 j an ac- count of which may be found in the Trans, of the royal soci- ety Lond. for that year. He fully and vei-y clearly explains, from the structure of the camel’s stomach, how that animal is enabled to take in a supply of water for future use, thus fitting him to live in sandy deserts, where supplies of water are precarious or scanty. Hr. Russel says he knew an instance of a camel in a Bas- sora caravan, remaining fifteen days without water j but none of the natives recollected a similar instance. Leo Afri- canus however mentions one. Descript. Africa;, lib 9, p. 281. Dr. Russel says that camels sometimes show a preference for salt w ater. Nat. History of Aleppo, vol 2, p. 167, 168, London, 1794, 4to. A’ote 40. Chemistry also has recently lent its aid to disprove a po- pular error, which has long prevailed respecting the origin of the salt familiar to most persons by the name of sal am- moniac, which was first brought to Europe from Egypt, and was said in early times to be formed by the action of the camel’s urine upon the sands of the desert, near the temple of Jupiter Ammon. Lemery and Pomet both give assent to this notion, and the latter, in his history of drugs, gives a plate of a camel in the act of discharging his urine, and the mass of salt forming in consequence of it under his body !* But the recent analysis of the urine of the camel, shows that ammonia exists in it in so small a proportion, as to render it impossible to suppose it could have the leasd; agency in the formation of the salt in question. The analysis of the urine of camels referred to, was made by two good chemists, in different countries, viz. Messrs. * Pomet on Drugs, page 250. London, 1737. The work was originally pub- lished in French, in 1694. Lemery derives ammonia from afxfjios, (ammos) arena, sand. Jfotes to Introductory Lecture, 45 Rouelle ia France and Mr. Brande in London, and their agreement in the general result, leaves no douht as to the accuracy of it. Analysis of the camel’s urine, as given by Mr. Home. BRANDE, ROUELLE.* Water, ... Phosphat of Lime, Muriat of Ammonia, j Sulphat of Po .ash, ^ Urat of Potash, ( Carbonat of Potash, J Muriat of Potash, Urea, . . . , 75 6 8 6 Carbonat of Potash, Sulphat of Potash, Muriat of Potash, Urea. * Thompson’s Chemistry, second Edition, vol. 4, page 655. 95 The urine of cows was also analyzed by both Mess. Brande and Rouelle, both of whom agree in stating that potash is the only fixed alkali in them. We now know that the salt which the ancients called sal ammoniac, was common salt : and that the true sal ammoni- ac is not found native. The Egyptians are stated to have procured it by sublimation from soot of cow’s or camel’s manure, urine and common salt ; but fi’om accounts trans- mitted to the royal society at Paris, it appears certainly that this salt is procured by sublimation from the soot taken alone without any addition. Nicholson’s Chemical Dictionary, vol. 1 , p. 116 ; and Magellan’s edition of CronstadCs Mineralogy, p. 458. The soot taken from the chimneys in which cow dung only, as fuel, is burnt, is said to furnish the best sal ammoniac. This salt is however commonly prepared from burnt bones, in the United States, and in Europe. From Vauquelin’s analysis of the urine of various animals, (Annales de Chimie, tom. 82, p. 197,) it appears that the urines of the lion and the tiger are perfectly similar, and differ from the human in some essential points. 1 . It is alkaline, even at the instant of being voided, and hence its bad odour 5 while the urine of a healthy man is al- ways acid. i6 e/Voies to Inlvoduclovij Lecture. 2. They do not contain any uric acid, nor any combination of this acid with the alkalis. The defect of uric acid in those urines, struck Mr. Vauquelin more forcibly, as he used to ascribe its formation to animal food. 3. They contain only a very small quantity of muriate of soda, (sea salt,) whereas that of man contains a great deal. We find in these urines, much urea, phosphates of soda and of ammonia, sulphate of potash, mucous matter, and a trace of iron. The urine of the heaver has a great resemblance to the urine of herhiverous animals ; that of a rabbit, con- tains lime, magnesia, and carbonate of potash, sulphates of potash and of lime, muriate of potash, urea, gelatine, and sulphur. He did not find any soda in the urines of the ca- mel, cow, Guinea pig, or rabbit. The urine of the horse, according toFourcroy and Vauquelin, (Thompson’s Chemis- try, vol. 4;,) contains carbonates of lime and of soda, much benzoat of soda, muriate of potash, and urea. Mr. Braude’s analysis of the horse’s urine, agrees with that of Messrs. Fourcroy and Vauquelin, but he also found in it sulphate of soda, muriate of soda, but no urea, potash or ammonia. Mr. Brande found that tlie urine of the ass contains a much great- er relative proportion of the phosphat of lime and urea, also carbonate, sulphate, and muriate of soda, and a small quan- tity of potash. The urine of both the horse and ass is des- titute of ammonia. The foregoing details of the urine of various animals are given, as being connected with the interests of agriculture ; urine having been found to be highly stimulant to vegeta- bles : and from the abundance of certain ingredients in that of a particular animal, and their deficiency in others, we may ascertain why certain urines are prejudicial, or useful to particular plants. JVotc 41. The notion of the submersion of swallows during winter is of Swedish origin. Olaus, the bishop of Upsal first promul- gated it, and naturalists more worthy of attention assented to Introductory Lecture. 47 to it. Linnseus confined submersion to ebimuey swallows and martins. Kalm his pupil believes the story, and begins the discussion of the subject by saying that “ natural history like all other histories depends not always upon the intrinsic degree of probability, but upon facts founded on the testi- mony of people of noted veracity.”* But this testimony must not violate probability, nor be inconsistent with one of the first rules of philosophising, viz. that “ like causes produce like efiTeets now, if we find that the lungs of two animals are constructed precisely alike, and that one of them cannot live under water, we must conclude that the other is also defi- cient in that same power. This is the ease with man and swallows: both are formed alike, and hence they must be sub- ject to the - same laws. Those w ho wish to see more on this question are referred to apaper I published (anonymously) in the Med. Repository of N. York, vol. 3, p. 241. — 1800. Bar- ton’s Fragments, Philad. 1799, Caldwell’s Memoirs, 1801, and to Observations on the brumal retreat of the sw allow s,” by Thomas Foster, F. Lin. Soc. London, 1813. The argu- ments of this author in favour of the sw allow being a bird of passage are indisputable : he has also annexed an index to passages relating to the sw allow in the w orks of the antients, and in modern European authors, which is curious and highly interesting. JVote 42. Adrian Vandervcdde was born in 1639 at Amsterdam, and was a pupil of John Wynants. He died at the age of 33. See further, Pilkington’s dictionary of painters, p. 686, ito. London, 1798, and Camper on the connexion between ana- tomy and drawing, &e, translated from the Dutch by Dr. Cogan, London, 1794.'^ ^ JV*ote 43. Aristotle long sinc^.remarked that the motion or steps of animals in general are made in the line of their diagonal : * Travels, vol. 2, p. 140, 4S JV'otes to Introductory Lecture. that is, in the dii'ection of their two opposite quarters. The absurdity of the error noticed is evident. But the camel forms a striking exception to the rule : he walks by raising the two legs of the same side, the one immediately after the other. AristoteL de hist, animal, lib. 11, cap. 1. Dr. Rus- sel confirms Aristotle’s statement. Nat. Hist, of Aleppo, vol. 3, p. 169, & p. 4-23. The engravings of the skeletons of some of the animals in Buffbn’s natural history, particularly of the horse, are very inaccurate. Artists should read the following works besides Camper’s. 1. Refleetions on the painting and sculpture of the Greeks, with instructions for the connoiscur, and an essay on grace in works of art, translated from the German original of the Abbe Winkleman, by Henry Fusseli, London, 1765 — 8vo. 2. Count Algarotti on painting, London, 17 63 — 12mo. 3. Dr. Brisbane on the anatomy of painting, with 6 plates, London, 1769. 4<. Essays on the anatomy of expression in painting, with plates, by Charles Bell, 4?to, London, 1804?. This last is by one of the first anatomists of the present day, and ought to be studied by every painter or engraver, of either man or animals. J^ote 44. Gentleman’s Magazine, 1790, p. 299. JV’otc 45. See an aecount of a case of croup in a calf, in memoirs of the Philadelphia society for promoting agriculture, vol. 3, by Mr. Peters, president of the society. 46. Alemoirs medical society, London, vol. 5. eA*ote 47. This disease has prevailed with great mortality in Phila- delphia county during the last spring. Mr. G. Montague gives some reasons, for believing that by mixing the food of foAvls with urine instead of water, and feeding them with it three or four times a day, it may he removed. Memoirs of J^'^otes to Introductory Lecture. 49 Wernerian Nat. Hist. Soe. Edinburgh, vol. 1. 1811. Mr. Peters informs me that he eures it by small pills of camphor, given twice a day. J\''otes 48, 49. Gentleman’s Magazine, 1790, page 497. JV’ofe 50. Mr. Lawrence, “ Philosophical and practical treatise on horses,” has justly ridiculed, and with much pleasantry, the absurd farrago of nostrums administered by farriers. JS''ote 51. 1 was told by an intelligent drover, that it is the cattle from the district of the long-leaved pine, that possess the power of diseasing other cattle. This species is the Finns vlustralis of Miehaux, Finns Falustris of Linnseus, the pitch pine, yellow pine, red pine, or broom pine. According to Miehaux, the country occupied by this pine commences near Norfolk, and continues in a south west direction for 250 leagues in length, and 40 to 50 in breadth. See Histoire dcs Jlrbres Forestiers de L’Amcr. Septent. Faris, 18i0. I Avould be very thankful for any information on the subject of the disease in question. We sec something similar to the dis- ease produced among northern cattle, by mixing with those from the south, in the human race. During the revolution war in the United States, the mixture of southern with northern troops, speedily induced disease, if encamped to- gether, although both had been previously healthy. See Rush’s Works, vol. 1. In like manner, the mixture of the crews of ships of different nations, at sea, has often produ- ced disease. See Blane’s diseases of seamen, page 235 ; and the arrival of a stranger at St. Kilda, one of the remote and small western islands of Scotland, produces a catarrh among the inhabitants. — Martin’s History of the Western Islands, page 284. The case of the South Carolina cattle is how ever peculiar. W'e do not find that those from other states pro- duce a similar complaint, or any other, w hen mixed with the stock of Pennsylvania. The fatal disease alluded to, that VOI.. III. I 50 ^'"otes to Introductovif Lecture. occurred in 1796, in one instance, at Columbia, on the Sus- quohannah, attacked stock vliich liad merely strolled about, or bad lain down in a ploughed field, in which the South Carolina cattle liad been previously penned for one night; a full proof of the virulence of the effluvia left by them on the ground. The precaution suggested by the foregoing facts, in grazing, and in armies and navies, is obvious. JYote 52. See Memoirs of the Philadelphia Society for promoting Agriculture, vol. 1, pages 139, 154. J\''ote 53. See account of this disease, by the Rev. Mr. Parsons, in the New York Medical Repository, vol. 1. J\'ote 54. See Archives of useful knowledge, vol. 1, page 398, and vol. 2, page 400. JVote 55. For Mr. Hunter's account of the inflammation of a vein from bleeding, (which is highly interesting,) see Transac- tions of a society for the improvement of medical and chi- rurgical knowledge, London, 1793, page 18. Also, Dorsey’s Surgery, vol. 1. The late Mr. Wignell, of the Philadelphia Theatre, died of this disease. Inflammation in the veins of horses or man, after bleed- ing, according to Hunter, arises from not fully closing the external wound, “ and when inflammation takes place be- yond the ^ orifice, the surgeon should immediately put a compress upon the vein, at the inflamed part, to make the two sides adhere together : or if they do not adhere, yet simple contact will be sufficient to prevent suppuration in tliis part : or if inflammation has gone so far as to make the surgeon suspect that suppuration has taken place, then the compress must be put upon that part of the vein just above the suppuration. This I once practiced, and as I suppose, with success.” If the disease proceeds, bleeding and other depleting remedies are to be used. Dr. Physick has applied ^'‘otes to Introductory Lecture. 51 a blister ^ver the part with success. Dorsey’s Surgery vol. 1. “ Upoa tracing the vessels, after death, from the inflamed part,” Mr. Hunter says, “ pus is found mixed with the blood. In some places the sides of the vein were adhering, and in others the ^nner surface of the vein was furred over with coagulable 1 miph.” J^ote S6. The cases of the cure of the disease produced by the bite of a mad dvg, in Calcutta, which have been recently pub- lished by Mr. Tymon, Dr. Shoolbred, and Dr. Berry, ought possibly to be adduced as exceptions to the general position ; but we must have more cures by the same remedy, before it can be Said to be safe. It never has succeeded before in any count 'j. See Medical Repository, vol. 2, New Series, and Eclectic Repertory, Philadelphia, vol. 3, for the cases al- luded Is). JS'^ote 57. Meta n. lib. 7. v. 523. Jfote 58. Liv^v, lib. 41. 59. M?m. Med. Soc. London, vol. 5, and Webster’s history of epide mic and pestilential diseases, vol. 1, pages 139 and 321. Harubrd, 1799. J\'’otes 60, 61. Webster, vol. 1, pages 86, 181, and other places. Mr. WeLster has rendered an essential benefit to medicine, by his gre 1 collection of facts on the subject of epidemic diseases, an ^by showing their connexion with, and occasional depen- dence on natural phfenomena. J lien