Digitized by the Internet Archive in 2016 https://archive.org/details/inquiryintouseof01rush AN INQUIRY #& &»***,& INTO THE USE OF THE OMENTUM. BY JAMES RUSH. OF PHILADELPHIA. PHILADELPHIA, FROM THE PRESS OF T. fcs* G.-PALMER. / 1809 . T > *• V * V4 AN INAUGURAL DISSERTATION FOR The Degree of Doctor of Medicine . SUBMITTED TO ) THE EXAMINATION OF THE REV. JOHN M‘DOWEL, LL. D. PROVOST, THE TRUSTEES AND MEDICAL PROFESSORS OF THE University of Pennsylvania. ON THE 19TH DAY OF APRIL, 1809 * . TO BENJAMIN RUSH, M. D PROFESSOR OF THE INSTITUTES AND PRACTICE OF MEDI- CINE, AND OF CLINICAL PRACTICE, IN THE UNIVERSITY OF PENNSYLVANIA. HONOURED SIR, For favours which I can neither express nor repay, I beg your acceptance, in this public manner, of the acknowledgments of your affectionate and grateful son and pupil, JAMES RUSH, • ♦ , * i . f r - , i ' c. , u; * P ' *:* :r ■*** i . . r :i , i : n • ' ;• - : ' o' l i i ’■ • ?1 ’ Y? •• ‘ V ALSO TO CASPAR WISTAR, M. D. PROFESSOR OF ANATOMY ; JAMES WOODHOUSE, M. D. PROFESSOR OF CHEMISTRY ; BENJAMIN SMITH BARTON, M. D. PROFESSOR OF MATERIA MEDICA, NATURAL HISTORY, AND BOTANY , AND TO PHILIP SYNG PHYSICK, M. D. AND JOHN SYNG DORSEY, M. D. UNITED PROFESSORS OF SURGERY, IN THE UNIVERSITY OF PENNSYLVANIA, AS A TESTIMONY OF GRATITUDE FOR THEIR CIVILITIES, AND THE INSTRUCTION DERIVED FROM THEIR LECTURES, THE FOLLOWING DISSERTATION IS INSCRIBED, BY THEIR OBLIGED FRIEND AND PUPIL, JAMES RUSH. • - - ' * * ■rr , . . V - i AN INQUIRY INTO THE USE OF THE OMENTUM. N O VEL opinions in science, like the essays of infant speech, are often faultering or false. Let it be considered, however, that the faulter may become the tone of authori- ty, and that error detected lessens the embarrassments of truth. These reflections countenance the attempts of theory, and encourage the adventurer with hope. It is true, the period has been anticipated when observation and books should have yielded their contribution to the writer ; but the subject has been entered upon, from a conviction that system in arrangement and method in reasoning, give their advantages to the framer. He who benefits an individual does a plausible duty, and such is his beneficence, who renders a service to himself. Truth lies hidden beneath the surface, and though theory cannot always make the discovery, it may work upon the spot of its concealment : a better occupation surely than his, who indolently waits, vainly imagining it will take root, and spring up under his feet. B 10 The theories or reasonings in physiology, and their importance to practice, have been particularly the ob- jects of cavil. Many of the functions of the human body can be explained only by analogy ; as if nature, for the comprehension of her noblest work, required the exertion of man’s noblest faculty. The enemies of physiology object not to its established, but to its un- known doctrines. The practical utility of those alrea- dy proved, are too obvious to admit of dispute. The circulation of the blood, the process of digestion, and the actions of the intestines, are truths, without the knowledge of which even the empiric could scarcely practise. These were the result of physiological re- searches ; and were once as obscure as many things yet to be discovered. This is my apology for considering a speculative subject in physiology. In the list of subjects for discussion, an inquiry into the use of the omentum in the animal structure, has been suggested by the doctrine of the office of sanguification, lately, ascribed to the liver, by my father*. To this function, he has also attributed the conversion of fat into the matter of nourishment for the body. This opinion I have embraced, and by its more particular application to explain the intention of the omentum, shall endeavour to treat it with more minuteness than the author himself has devoted to it in his lectures. '* See Medical Museum, Yol. Ill — Dr. Rush on the functions of the liver, spleen, See. il It would be tedious to consider, at length, the struc- ture and other anatomical circumstances of the omen- tum. It will be sufficient to observe, that it is a pen- dulous membranous body, folded so as to form a cavity resembling a sack ; attached to the stomach by its ante- rior, and to the colon by its posterior fold ; hanging between the anterior parietes of the abdomen and in- testines ; extending commonly as low as the umbili- cus. It consists of two thin membranes, united by cellular substance, and ia well supplied with blood- vessels. The cellular substance uniting these two membranes is the seat of the fat, which is the more im- mediate object of this essay. The uses ascribed to the omentum have been many and various ; some of those generally received shall be the objects of consideration. I. Its office has been supposed to prevent the injuries from the friction of the intestines upon each other, by furnishing an oleaginous fluid to lubricate them. It has long been the practice of physiologists, to measure the intentions of nature by their own ingenu- ity. Hence the explanations of the pulsations of the heart ; of the equilibrium given to the body by the spleen ; and of the lubricating quality of the omentum. I object to this opinion, first, because it is too mechani- cal. Although, strictly considered, every natural opera- tion must be mechanical, yet physiology has often suf- fered from a confusion of the attenuated laws of vital action, with the grosser rules of the arts or mechanism 12 of common life. Secondly, it is not necessary . We know that moisture alone, is sufficient to give facility of motion to parts pliant and polished ; now the in- testines are under these circumstances, with regard to themselves, and the peritoneum. Thirdly, by its fat it cannot lubricate the intestines . The omentum is not a fat-secreting surface, but a fat-containing cavi- ty : its surface affording nothing except that moisture which is natural to all internal membranes, and this I have spoken of as abundantly supplied without the aid of the omentum. Fourthly, the supposition that it is to prevent friction , only substitutes, for attrition, a substance less regular and yielding than the peritone- um it is intended to cover. II. A second use which has been ascribed to the omentum is, that it is intended, with other abdominal viscera, to prepare blood for the formation of bile. Here, from an accidental, and at the same time an un- avoidable circumstance, is deduced a conclusion not warranted by any proof : accidental, as the liver was placed in the cavity of the abdomen, and unavoidable , as it could receive its blood from the viscera of no other part. If we infer from this situation of the liver, that a change takes place in the blood of the vena por- tarum, this change must be produced by each particu- lar viscus, or it must be the joint operation of all. It cannot be the former, for each of the several parts se- creting a different substance from the blood, must give a different quality of blood to be returned. If it be the 13 latter, disease in those parts must prevent the formation of the peculiar hepatic blood. Let it not be said, that disease or obstruction of these preparing viscera is often attended or followed by fatal consequences to the system. To this it may be answered, that these parts are vital in other respects than their relation to the cir- culation of the blood. Moreover, if the bile require this oily secretion, why is the fat thrown out into cells ? It ought to pass directly on to the liver through the veins ; as this is not its course, it can get there only- through the medium of the absorbents. To suppose it first secreted, effused into cavities, and afterwards taken up by lymphatics, is to admit a prolix, where nature has a more simple process. This opinion is grounded upon the fact, of fat being found in the omental branches of the vena portarum ; and from this has been explained the oily nature of the bile. The inference from this fact is, that the liver is not a secretory organ, but a filter. It is impos- sible however that acini so minute as to prevent the passage of blood, should give admission to so viscid a substance as fat, of such a size as to be the object of examination by the eye. The bile does not derive its oily nature from the fat ; we have seen that it cannot pass by filtration, it must undergo the secretory ac- tion. Now the very essence of secretion is an altera- tion of chemical properties, which if the fat suffer, it cannot form the oil of the bile, for, take the most minute portion of its principles away, and you destroy its nature as fat. 14 III. A third opinion advocated for the use of this vis- cus, is that it serves to keep the intestines warm. If this should need a refutation, I would observe : First, it will apply only to hybernating animals. In their living state, nature has prevented the evil arising from a de- fect of warmth, by placing these viscera near the great- est source of heat. Secondly, if it were true, die want of such a provision would be felt elsew here. Why has not the brain its hood, or why is the thorax without its breast- plate ? This opinion is deduced from the fact, that very fat people feel the cold less sensibly than those who are lean. But this is to be ascribed to the effect it has upon the nerves. Richerand, in speaking of the uses of the fat, says, “ and finally, it covers and surrounds the extremities of the nerves, diminishing their suscep- tibility, which is always in an inverse proportion to cor- pulency .” Again, “ In fact, persons subject to nervous affections, constantly join an extreme leanness to an ex- cessive sensibility Other opinions of the uses of this organ have been proposed. They will be omitted to give place to one, to the support of which the following pages shall be devoted. I shall endeavour to prove the omentum to be an or- gan for the secretion of fat , furnished with vesicula for its reception , in order to supply the body with nourish- ment , when the resources by the stomach fail. * Physiology. Article Ixxvi. 15 The arguments for the support of this proposition will be deferred, till the consideration of some circum- stances which are connected with this view of the sub- ject. That fat nourishes the body in certain states is no new idea ; the phenomena of its existence were too ob- vious not to lead to that conclusion. As an old doc- trine, it has little meaning. Blood is the only medium of nourishment with which we are acquainted ; but the fat has not yet become blood. How is this effected ? It may be said that it is produced by the lymphatics and their glandular system. This may be answer- ed, by observing, First, whatever change is the effect of their action, it is certain they do not completely con- vert it into blood ; nay, they do not even form a chylous substance, but a more limpid fluid. Secondly, fat has been found in the branches of the vena portarum. A sufficient proof that it has passed, with little or no alter- ation, the action of the lymphatics : it being immaterial whether it has gotten into the veins by a set of partial vessels, or has passed the circle of the general absor- bent system. The change then must be made after it enters the circulation, and nowhere is there a cause ade- quate to that, except in the lungs or the liver. It can- not be in the lungs, for chyle has been found in the blood after it has passed through them. It remains then for the liver to perform the office in question, and this I shall now consider more in de- tail. 16 “ The design of the liver,” says the author, in the essay referred to, “I believe to be, to receive the blood from every part of the body, in order to subject that part of it which has not been completely animalized, or divested of its chylous properties, to a secretory process, and afterwards to pour the product of this secretion, mixed with the liquor of the pancreas, into the duodenum, to be absorbed or otherwise taken up by the lacteals, and conveyed with the chyle from the stomach iiiio the bloocl-vessels, in order to be com- pletely converted into red blood, for the purpose of serving the various and important uses for which that fluid is intended in the human body.” It would con- sume too much time to give, at large, the facts and rea- sonings used by the author to support this proposition. I shall give an abstract of them. The same power that perfects the chyle, converts the fat to a like matter ; and as this is one of the ideas embraced by this essay, its proof may be required. The arguments in support of this doctrine are, “ 1st. The presence of the liver, in nearly all ani- mals, being in this respect on a footing with the sto- mach.” “ 2d. The immense and disproportionate size of the liver in the foetus, compared with that of the adult, the design of which appears to be, that nourishment may be carried on exclusively by that viscus, without any aid from the stomach.” 17 £t 3d. The size of the liver in adults, and 4he quan- tity of bile secreted, said by Haller to be twenty -four ounces in 24 hours.” “ 4th. Chyle has been found in the blood after it has passed through the lungs ; hence it requires another process.” “ 5th. The quality of the venous blood from which the bile is secreted. It is less disposed to putrefaction than arterial blood in any part of the body. This arises from the chyle it contains, as chyle is less putrescent than blood.” “ 6th. The quality of hepatic bile, it being sweet. Haller says, “dulcior hepatica cystica arnara. ” “ 7th. Sever 4 experiments of Dr. Fordyee prove chyle to be formed by the action of saliva and gastric juice upon the aliment, without the mixture of hepatic bile.” “ 8th. The structure, situation, and function ot the pancreas. It resembles the salivary giands in its struc- ture ; it secretes a liquor which possesses the same dis- solving and animalizing properties as the saliva ; and it pours this liquor so directly upon the hepatic bile, as to change it into perfect chyle.” “ 9th. It is inferred that a second chylopoietic pro- cess goes on in the liver, from the effects of intempe- rance upon it. It increases its labour, and thereby in- creases its size.” To the above arguments in support of this opinion of the function of the liver, I shall add the foil on ing ob- servations. Doctor Pemberton, in his treatise upon the c 18 diseases of the viscera*, has taken a view of the glands of the body, as divided into those that secrete a fluid from the blood for the use of the system, and those that secrete a fluid to be discharged from it. The former he has called glands of supply ; the latter, glands of waste. He has satisfactorily shown, that derangements of the glands of waste are not attended by any altera- tion ill the bulk of the body ; whereas disease in the glands of supply, in almost every case, produces emaci- ation. The liver is an organ, the diseases and disorders of which cause a wasting of the flesh. This gives it a place among the glands of supply. I would however infer that it serves this purpose, more than is generally allowed ; for if so great a quantity of bile as 24 ounces, which is secreted in 24 hours, be not excrementitious, how considerable must its effect be in nourishing the body ! It is known that gall-stones obstructing the biliary ducts produce emaciation. This has been as- cribed to the effect of the irritation of pain upon the system. I would rather suppose it to be owing to the obstruction to the flow of bile, when the stone is in the ductus communis ; and when it is in the cystic duct, to the irritation, by continuous sympathy, causing a vitiated secretion of bile. With these views of the liver as established premi- ses, I shall proceed to exhibit the proofs of the proposi- * See “A Practical Treatise on Various Diseases of the Abdo- minal Viscera,” by C. R, Pemberton. 19 tion laid down, on the subject of the intention of the omentum. This viscus seems not to be one of those whose use is inscribed upon it so legibly, as not to need the efforts of reason to decypher it. The appearance it exhibits to the eye, is not sufficient to manifest its operations. It is of such inconsiderable importance to the animal sys- tem, as not to give by its own derangements any very sensible alteration to the functions of the body, or at any rate it has its office vicariously supplied. From this view we may see why the separation of parts of it, its adhesions, and every other preternatural state of it, have so little effect upon the body. Hence too the dif- culty and inefficacy of any experiments, to which it could be subjected. There exist, however, facts enough con- nected with its ordinary phenomena, as exhibited after disease, to afford just conclusions of its use. To this add its fitness for the office here ascribed to it. For though the sufficiency of a cause be not an undeniable argument for its agency, yet it is essential to proof. It has been said before, that the omentum is an organ for the secretion of fat , furnished with cells for its re- ception. This is true, whatever be the intention of the fat when secreted. It is true, because it is seen. I know of no other argument for its proof. Beside the evidence of our senses, proof requires the media- tion of axioms. There is no assertion more self-evi- dent. I might indeed vary its form, but, like the revo- lutions of a sphere, it would not bring a greater com pass into view*. The second part of the proposition to be considered is, that the omentum is intended for the purpose of sup- plying the body with nourishment when the resources by the stomach fad. My behei in this arises from the following