Addresses, Papers and DiscDssiflns IN T:^E SBCTION OF. AND NEUROLOGY, AT THE PORT Y-SECGMnNBUAL MEETING OF THE AMERICAN MEDICAL ASSOGUTION; At Washington', D.,C., IVTay5-fi, 1 89 1 . CHICAGO: Printed at the OPpic'E of the Association 1891. • ■ THE GIFT OF J^. ^Jj£u^^ ..^$Jjlf...i... INDEX. Karly Physical Symptoms of Traumatic Brain Injuries. Crothers ... ... i The Neuroses from a Demographic Point of View. Rosse. . 13 Status Epilepticus. Trowbridge and Mayberry 25 Functional Brain Degeneracy. Searcy 51 The Virile and other Nervous Reflexes. Hughes. 79 A. Case of Idiopathic Spinal Hsemorrhage. Diller 91 The Diagnosis of Traumatic lycsions in the Cerebro-Spinal Axis and the Detection of Malingering Referred to this Centre. Watson. 95 A Consideration of Traumatic Lesions of the Spine Resulting from Railroad and other Injuries; their Etiology, Pathol- ogy and Diagnosis. Manley ^ 119 Electro-diagnosis in Brain and Nerve Injuries. Methods Used and the Apparatus Required. Walling . '. ... 173 Ligation Disease a Form of Neurosis. Judd . • • ■ 195 Paretic Dementia and Life Insurance. Kiernan . . ... 211 Medico-Legal Investigation of Deaths by Violence in Massa- chusetts. Presbery . 219 Ether Inebriety. Kerr. . . 229 Synopsis of Opium Inebriety; Effect, Needed Legislation, Dis- tinctive Plans of Treatment Necessary for the Successful Cure. Watson. . . . . r. 243 The Absence of Reasonable Motive in the So-called "Criminal Acts" of the Confirmed Inebriate. Mason. 259 Personality as it Affects the Course of Drunkenness. Wiight. 277 Treatment of the Opium Neurosis. Lett . . 299 Does Science Justify the Use of Alcohol in Therapeutics. If so, when? vrhere? Chenery. . . . . 317 Insanity as Related to Civilization. Everts. 333 Studies of Criminals. Degeneracy of Cranial and Maxillary Development in the Criminal Cl-ass, with a Series of Illus- trations of Criminal Skulls, and Histories Typical of the Physical Degeneracy of the Criminal. Lydston and Talbot. 353 The original of tliis book is in tine Cornell University Library. There are no known copyright restrictions in the United States on the use of the text. http://www.archive.org/details/cu31924031303567 EARIvY PSYCHICAI, SYMPTOMS OF TRAUMATIC BRAIN INJURIES.' BYT. D. CROTHERS, M.D., OF HARTFORD, CONN. The department of neurology in the practice of medicine has attained such proportions that it would be almost impossible in the limits of a single paper to give any complete history of the advances of even one year. In this country there are six large journals devoted exclusively to this branch. Five quar- terlies and one monthly, viz: The Journal of In- sanity; The Alienist and Neurologist; The Jour- nal of Psychology; The Journal of Mental and Nervous Dise,ases; The Journal of Inebriety; and The Review of Insanity and Nervous Diseases. Abroad, the periodical literature is more vol- uminous, and books and pamphlets follow each other rapidly. A neurological library of to- day, to be complete, would number thousands of vol- umes and pamphlets. This would be exclusive of the literature which I Address by the Chairman of the Section. appears in the general journals, comprising rec- ords of cases, theories, and discussions of diseases of the brain and nervous system. The different fields of neurology have been studied until the specialists find it almost impos- sible to master more than a single phase of the subject. The lunacy specialists, the specialists of nervous diseases, the specialists of alcohol and drug diseases, the specialists of idiocy and con- genital diseases, the experimenter and teacher of psychology, and the electrician are all ex- amples. The unknown regions of the physiology and pathology of the brain and nervous system are attracting an increasing number of most ardent students, and already the discoveries are very numerous and startling, and the process of learn- ing and unlearning is more and more difficult. In the department of Medical Jurisprudence prog- ress and change is less rapid. Seven medico- legal societies and one large quarterly present the many practical topics which are constantly appearing. The confusion of theory and practice in both law and medicine, relating to questions of crime and responsibility, has given rise to many strange conceptions of the teachings of science. Thus, from the text books and legal rulings of judges, the lines of sanity and insanity are laid down as absolute facts. Free will, and accountability, judgment, punishment, equity, with brain con- trol and capacity, are regarded as settled facts, based altogether on theory. All these questions comprise a realm of the densest superstition and error that will continue until studied scientifi- cally. To- day the student of medical j urisprudence must pursue his studies above all present theo- ries, text books and rulings of law. The ques- tions of motive and human conduct must be de- cided from a knowledge of natural laws of physi- ological and psychological growth. Science calls for a great revolution and evolu- tion in the medico-legal solution of many of the disputed questions of to-day. The insane, the inebriate, the defectives of all grades and condi- tions, and the tramp and criminal, can never be restrained or prevented from being sources of peril to all law and order, on theory, or meta- physical abstractions of mind, or legal rulings. Medical jurisprudence of the future must de- pend on the progress of scientific medicine. Both neurology and j urisprudence are largely influenced by the neurotic element of American civilization. This is a tremendous factor in de- generation and disease, and enters into all de- grees of life and living. The family physician and general practitioner are most favorably situated to become the earliest and most accurate students of most of those con- fusing problems in neurology and jurisprudence. Every year it is more and more apparent that the failure to recognize the early symptoms of brain degeneration and disease, constantly in- creases the army of incurables. The crowded insane asylums, alms-houses, jails and hospitals, all refer back to early neglect, and failure to rec- ognize and apply the means of prevention and cure. A clearer knowledge of neurology would point to conditions and methods of treatment that could be successfully applied at that time only. An outline view of some of those early stages is the central topic of this paper. There is probably no one disease more often mistaken in its early stages than general paraly- sis. Even after the symptoms have become ap- parent, there are confusing halts, and a delusive masking of symptoms that often puzzles even experts. A long formative stage precedes the well-defined symptoms, beginning in slight changes of conduct and character, elation of spirits, increased activity of the intellect; the disposition, the manner, the temper, the habits, and general character all become altered. Then come acts and words which are unusual, the friends and associates are conscious of some change which they seek to remedy by moral ad- vice. Finally, when some reckless conduct or strange disposition is manifest, the physician is called and the disease is clearly made out. To the patient this has no foundation in fact, and sometimes the physician joins in this belief, and explains these changes of mind and conduct from some moral basis. Symptoms of alcoholic and sexual excesses are explained in the same way. After a period extending over months and years in many cases, the disease is above all question, and beyond all medical skill. This formative stage has been attended by distress, loss, sorrow and most serious blunders. In some cases, crim- inal acts and sad domestic and pecuniary afflic- tions have marked this period. If the family physician had made an early diagnosis, and the treatment been based on this, a different history and result would have followed. Some of the ataxies have a similar obscure, early stage, marked by psychical disturbances which are regarded as moral lapses. Nearly all forms of insanity begin with this obscure failure of the high brain centers. Early changes of temper, conduct and character, defects of emo- tional control, defects of reason, slight and ob- scure at first, and yet clearly the oncoming shad- ows of diseases that should be anticipated and pointed out. These changes and early symptoms are not new to science, but in most cases, they are overlooked and seldom receive the attention they deserve. There is a class of symptoms that are already becoming the center of serious controversy. They are not only not recognized in the early stages, but are sharply disputed by both laymen and physicians. I refer to the alcoholic, opium and other drug symptoms, which are affirmed to be purely vicious acts and the voluntary giving way to the lower animal impulses. Public opinion has sought to control them by fine and impris- onment. The medical profession accepts this the- ory of treatment, only asserting after a time, the use of these drugs brings on diseased states. The impulse for alcohol and other narcotic drugs is al- ways a symptom of some form of brain palsy. There are two classes of these cases in which this fact seems very clear. The first class are those with a history of some distinct traumatism — no- ticeably, sunstroke, blows on the head, profound wasting illness and severe injury of any kind. Recovery follows, but with it appear changes of temper, character and emotions, then comes the drink impulse or the use of some form of opium. These drugs cover up other changes and are interpreted to be the cause of all subse- quent degeneration and disease. Many of these cases die of pneumonia or some other acute disease, others go on to insanity and become inmates of asylums, while the majority remain as common drunkards or inebriates slowly growing worse year after year. They are treated as low, voluntary inebriates, despised, persecuted and punished, and die the centers of wretchedness and misery, and frequently leave defective families that are always burdens to the world. The second class of inebriates or drug takers have a distinct history of psychical traumatism. A man previously temperate and well, will have a history of profound mental shock, such as sud- den overwhelming grief at the loss of wife, or children, or property, or the failure to realize some absorbing ambition, or some calamity that will distress him acutely. His entire character and disposition will change, and the drink im- pulse will appear suddenly, without any cause, and continue persistently. Several instances have been noted in which the effect of a railroad accident, where no exter- nal injury was produced, was the beginning of the drink impulse. The shock of sudden fear seemed to so paralyze the brain as to demand alcohol or opium ever after. In these cases, alcohol may be taken at first as a medicine and in moderation, but the degeneration which calls for it is apparent when efforts are made to dis- continue its use. Another class of cases show these symptoms equally marked; thus persons who occupy centers of great care and business or professional responsibility; persons who are most active in business in the prime of life, pre- viously temperate, who suddenly begin to take spirits and rapidly become excessive drinkers, and defenders of its value as a medicine. Such cases are soon incapacitated and die. The drink symptom is always treated as a moral condition in these cases. In the first class of physical traumatisms some form of brain degeneration is apparent in this morbid impulse for alcohol and opium. The be- ginning and progress of the case confirms this. In the second class of psychical traumatism, a brain palsy and siidden perversion of brain func- tion and activity takes place, and the demand 8 for alcohol and opium is the expression of this state. In the third class, the use of spirits is a symp- tom of exhaustion and general brain failure. All these forms of palsy and degeneration are rapidly intensified by the chemical action of the spirit or drug used. The pathological condition which calls for re- lief by these drugs has a uniform order of events, beginning at a certain point and passing down, marked by a regular succession of symptoms, reaching a certain termination that rarely varies. The drink craze is a symptom which should never be misinterpreted or overlooked. Any one who persists in using alcohol or opium to ex- cess is suffering from some brain degeneration and ■ disease, which requires medical study and care. The use of alcohol or other drugs is, in a cer- tain number of cases, a marked symptom of in- sanity. This fact has been noted for many years, and generally occurs in neurotics who, after some great strain or mental perturbation, become ex- cessive users of spirits, and continuously or at intervals, stupify themselves with such drugs. When arrested and deprived of spirits in jails, acute mania or melancholy follows; then it ap- pears that the spiiit and drug craze were only symptoms of insanity concealed and masked by the spirits. The facts in this direction are numerous and startling, and unknown except to the few stu- dents who are at work in this field. Scientific study has established this fact, viz. : that the "drink craze" ("meaning the impulsive, unreasoning desire for spirits or narcotics) is a symptom of disease. Whether this is so in all cases at the beginning is not yet established; yet nothing can be more certain than this, that the use of spirits will cause disease and diseased con- ditions in all cases. Another fact is becoming more prominent, that, .the number of inebriates of all forms is increas- ing; and with them the army of neurotics and defectives is likewise rapidly growing larger. The problems of causation, prevention and cure are still involved in the realms of obscurity and quackery. Great parties and numerous societies are attempting its solution frorn the moral side alone. As a scientific problem, it is practically un- known, and yet, no question of modern times is so eminently one of causes and conditions that are tangible and within the range of science to understand. The neurologist must point out the road and stimulate the family physician to study these early psychical symptoms, which, like signal flags of distress, are becoming more apparent. Scientifically the abnormality of an increasing army of neurotics and suicidal drug takers, who receive no care or medical attention until they are chronic, is a reflection on modern medicine. Over five million of laymen in this country are agitating the question of means and remedies lO to check this disease. Of the sixty thousand physicians, less than a hundred have given any special attention to the cure and prevention of this wide reaching malady. The specialists can study these cases in asy- lums, but the family physician must be the scien- tific student to point out the early causes and remedies. The drink problem can never be solved except from physiological and psycholog- ical study. This must begin with heredity, growth, nutrition, culture, surroundings and all the phenomena of life. The early psychical symptoms must be studied also, the traumatisms, the beginnings of patho- logical changes that manifest themselves in the drink impulse. This is the path along which science must seek the solution of this problem. The temper- ance agitator and reformer must give way to the physician. The roar and conflict of parties and societies will die away, and only the voice of science will be heard. Then the armies of ine- briates, criminals, and insane will be halted, dis- banded and forced back to health and rational living. The inebriates will be protected and housed. The saloon will disappear, and alcohol will be unknown. This will be a reality when medical men take up this study from a purely scientific point of view. In discussion Dr. Kiernan said: He thought that Dr. Crothers did not fully appreciate the legal difficulties in caring for the inebriate. It is only when he has reached crim- inality that the law becomes efficient in restrain- ing his morbid appetite. Additional difficulty ■was added to these cases by the confused rulings ■of courts regarding tests of criminal responsibil- ity. There were, however, signs of advancement^ and a disposition to yield time honored but «rroneous precedents. Inebriates should have the same legal status as lunatics. THE NEUROSES FROM A DEMOGRAPHIC POINT OF VIEW. BY IRVING C. ROSSE, M.D., OF "WASHINGTON, D. 0. The title of this paper may seem rather an ambitious one, since the study of vital and social statistics, and their application to the compara- tive study of races and nations, is almost too new to furnish many principles that may serve as bases of induction. However, I purpose to state in a fragmentary way a few notes and observa- tions bearing on the subject. More than usual experience as a traveller has brought me in contact with various races of men under different mesological conditions. Experi- ence and observation in this line show that, in spite of physical and moral varieties, there exists practically, for the physician, but one people, since there are no wide differences, biologically or medically speaking, in the human species; and the infirmities of men, notwithstanding their physical inequalities and the extensive range of the nosological table, are much the same the 14 world over, no matter whether they be classified among the white, the yellow, or the black races^ I confine myself advisedly to the simple classi- fication of white, yellow and black, as it seems- to be the best for descriptive anthropological pur- poses, and is, moreover, that adopted by Aris- totle, Cuvier, and by a recent contemporarj- au- thority, Dr. Latham. In the consideration of ethnological subjects there seems to be an inability, on the p&rt of some people, to rid the mind of such abstractions. as geographical lines and political distinctions, though it is well known that they will not keep- away disease or noxious products. Indeed, the prejudice is carried so far that one might infer the notion that being born in a stable makes one a horse. We should not lose sight of the fact that the offspring of an English man and woman. in Africa will partake of the ethnological chara€>- teristics of the Anglo-Saxon race for all time to- come, so far as we know, and that the descend- ants of a black African man and woman in America will perpetuate the negro type witb marked persistency. The latter fact is so well established that in studying cases of the crossing. of the colored races, families have been observed in which, at the end of several generations, there were a series of children having much more thaik their father and mother the signs of an Africaa mixture, going back at least to a fifth anterior generation. A woman whose father was a quad- roon and whose mother showed traces of Africais 15 blood, having married an Englishman of pure race, had nineteen children, all of whom showed unequivocal traces of this sixteenth of African blood (Bulletin de la Soc. d' Anthropologic, 1865, p. 288). Among the motley population of the West Indies, it is noticeable that the African negro, transplanted to a sky but a little differ- ent from his own, has scarcely undergone any physical or moral modification ; in fact, he flour- ishes in the Antilles like the green bay tree, na- ture there being so much in his favor that after successive generations of mulattoes, the children revert to the negro type. Of course I do not pre- tend to deny the influence of meteorological con- ditions. Food and drink, and social and political surroundings; the conception of the remotest past and a forecast of the remotest future circumstan- ces ; everything in space, from a man's shirt to the farthest nebulae and deepest stratum of earth that he can infer, are but parts of the tremendous whole that acts upon man, or that he can act upon. In the climate of the West Indies, for instance, which Darwin speaks of as a great wild, untidy, luxuriant hothouse, the combined efiect of hu- midity with extreme heat softens, relaxes and impairs the fibres in men and animals, renders them lazy, inert, phlegmatic, and reduces them promptly to a state of complete atony. In these islands of indolence, even mosquitoes are lazy, and appear supremely indifferent when compared with the ones that I have seen inside the Arctic i6 circle in Northern Alaska. Fish are not game. It is related with some show of authenticity, as evidence of climatic result, that the tarpon has allowed itself to be caught by fishermen who dived to the bottom and placed a hook in its mouth. Mice are also wanting in the alacrity that characterizes the northern species. Imported quadrupeds weaken and degenerate rapidly. The hog alone flourishes. Frenchmen do not accli- mate and flourish in the Caribbean climate as they do, for instance, in Canada, under the same isotherm as Denmark, and Dr. Rochoux declares that families who are not from time to time re- cruited become extinguished in the third and fourth generation. It is true that atmospheric vicissitudes have much to do with the sicknesses of all latitudes, and may impart a different shade of color to a malady, that is produced by a sort of anatomical determinism. Meteorological influences of the climate modify the telluric conditions, alimenta- tion, habits, etc., yet as regards climate, obser- vation and experience seem to be our only guides. Up to the present time, climatology has given us many figures with but few results, and topogra- phy teaches nothing upon the salubrity of a coun- try. It does not explain why cholera is in India, plague in Egypt, and yellow fever on the shores of the Gulf of Mexico. Nor does it tell why malarial fevers spare New Caledonia, in spite of the existence of numerous marshes, and why 17 they ravage Madagascar in spite of its grand chain of mountains. We, of course, do not look for sunstroke and malarial fevers among Eskimo, nor for frost bites and snow blindness among the natives of tropical Africa, yet I have found locomotor ataxia equal- ly in Hayti and New York, and have seen the prevailing geophagism of the Antilles and South America among negroes of the Southern States. This neurosis of the function of digestion is not the exclusive infirmity of degraded and prim- itive negro tribes. Pathological geophagy is found among the yellow races' in Java, China and Siberia. It has been observed in the white race in some of the provinces of Spain, and among the poorer classes of whites inhabiting the pine barrens and thinly settled portions of several Southern States. Gastric depravity is not confined to human Ijeings. Collective investigation on this subject enables me to mention numerous instances. I have known a sow to eat her whole litter of pigs, and I have seen coprophagy in one of the elephants confined in the I/ondon Zoological Gar- den, On observing the habits of the fur seal during four visits to the Prybolof Islands, I have learned that these animals are in the habit of swallowing stones. The lithoborous habits were confirmed by finding in many stomachs stones weighing J^ lb. apiece. One paunch contained in the aggregate over 5 lbs. of large pebbles, and in the stomach of one sea lion there were found i8 more than lo lbs. of stones, some of them of great size. If such facts as the foregoing convince the bi- ologist of the identity of pathological phenomena occurring in the animal series with those ob- served in man, it is more striking from an anthro- popathological point of view that there is strong- er relation among diseases of men of all races,, in all climates. Nervous diseases form no excep- tion to this principle ; for in a general way it is. true that all species suffer nearly in the same manner when exposed to the action of the same morbid causes. In a retrospective way it is quite possible for a neurologist to study at the present time some of the convulsive manifestations of the Middle Ages ; and if we have the snake worship, magi- cal associations and nocturnal mysteries of voo- douism in Africa and Hayti, is not our own country preeminently the land of spiritualists, mesmerism, soothsaying, and mystical congrega- tions ? Much of my practice having been among Jews, I have had occasion to notice the calm, sober, and sedentary manners of that cosmopolitan race, in whom the prolonged influence of climate has certainly caused no material transformation of type. The world over, they preserve the Semitic stamp, and observe the excellent hygienic code that secures them such pathological immunity- that it is said they are less often struck by light- ning than other people. On the other hand, the 19 phenomena of nervous and mental disease are more frequent in them than in other races. We find familiar examples of strange nervous manifestations in such circumstances as a dance among the Sioux Indians, or a revival among the Anglo-Saxons at a camp-meeting. At both many of the participants will sing, laugh, weep, foam at the mouth, and fall exhausted in a faint or swoon. Analogous conditions of nerve disturbance may be found equally among the black inhabitants of equatorial latitudes and the Hyperborean Mon- goligse who live under the midnight sun. Be- sides gross anatomical differences in the negro and a difference of personal essence, so to speak, we find an obtusion of peripheral sensibility, said to be owing to flattening of the tactile corpuscle. There is a want of fineness in the reflexes, les- sened sensibility to alcohol, small intensity of nerve action, and, according to some observers, difference in the electrical state. I have noted similar things among the Eskimo of Bering Strait, the Tchutchkis of Arctic Siberia, and among the Innuit population generally. The nervous derangements of the Northern tribes, who, by the way, believe in and practice Sha- manism, go to show that nervous diseases are not, as many people believe, confined to civiliza- tion. Among these people I have seen insomnia, epilepsy, chorea, cerebral haemorrhage, paraple- gia and hemiplegia, and suicidal mania. A nervous affection known in the State of 20 Maine as the jumping disease, has its analogue in the Siberian emeryaki, so prevalent in the vi- cinity of Jakutsk. I may remark incidentally that, in the original account of this affection given to the public, the word was incorrectly spelled. Dr. Bunge, of St. Petersburg, writes me that it should be written emeryaki in order to approximate its Russian pronunciation. There is, besides, emeryak, the male patient; emeryaki, emyraka, the female patient ; and finally a verb, emery atschitz, to be affected with this disease. My friend, Lieut. Schutze, of the Navy, who has seen much of this disease, thinks it is owing to excessive consumption of tea and tobacco, and psychic depression of isolated communities and long polar nights. The ancient habit of tattooing is still common among school-boys, sailors, soldiers, criminals, and prostitutes living in so-called civilized com- munities. The practice, generally confined to a low grade of development and originating in perversion of the sexual instinct, is found pretty much over the world, notably in the Polynesian Islands and some parts of Japan, and I have been struck with the similarity of design on the chins of women when visiting two places so far apart as Morocco and Saint Lawrence Island. To anticipate criticism for mentioning what may seem a very trivial subject, I would say that tat- tooing is significant from a medico-legal point of view, no less a person than the Lord Chief Jus- 21 tice of England, having characterized it as a matter of vital importance. As regards perversions of the sexual instinct and outrages on morals, our common humanity seems to have much the same aptitudes and in- stincts, regardless of the points of the compass. Even a superficial observance of the sexual morals of the Eskimo causes one to smile at I hypodermically; a few minutes after he had a single fit, and this was followed by sleep. This same dose was repeated at 6 and 9 p.m. Slept all night. No convul- sions in the morning, no excitement. An inter- esting feature of this attack is the absence of excitement, which has always before followed status epilepticus in this patient. Casey. — Admitted July 8, 1889. Male, aged 38; family history of insanity and epilepsy. On January 4, 1890, was attacked with status epilep- ticus, though since admission has only had five convulsions; fits followed each other so closely that attendants were unable to count them. When first seen, the convulsive stage had nearly ceased. Ether was administered, and morphine hypodermically. The convulsions were stopped entirely, but the man died in the second stage f^om exhaustion forty-eight hours after the com- mencement of the attack. Case 8. — Male, aged 26^ no known heredity; a deaf-mute; febrile disease in early childhood 39 is the supposed cause of epilepsy; has had an average of -five epileptic fits a month while under a mixed tonic and bromide treatment; physical condition is usually good, but at present some- what impaired from constant use of bromides. May 25 had a series of convulsions in the night, number unknown, but when first seen he was passing from one fit to another without any marked interval. Given hyoscine hydrobrom, , gr. tItj, hypodermically, at 4 a.m. Slept until 7 A.M., and was then awakened by a convulsion, which was immediately followed by others; giv- en amyl nitrite by inhalation, without effect; ether administered, and chloral, grs. xxx, per rectum, with but a temporary cessation of con- vulsions; 12 M., coninae hydrobrom., grs. yus, hypodermically, after which the fits ceased and sleep ensued. At this time his physical condi- tion was bad; temperature 104° F., pulse 142, body covered with cold perspiration, face cyan- otic, hands and feet cold. At 9 p.m. he was somewhat restless, although there had been no recurrence of the convulsions; slight muscular movements in different parts of the body. Given nourishment and whisky per nasal tube, an enema, digitalin and coninae hydrobrom. , aa, gr. ■jl„, and atropise sulph., gr. -g\, hypodermically. Slept during the night without a convulsion, and is less stupid this morning; takes nourishment and stimulants. From this time he improved grad- ually, and in five days was about the ward again. Case p. — Same patient as Case 8. For past 40 two months has had no convulsions under a mixed tonic and bromide treatment. August 20, at 2:30 P.M., an attack began similar to the last; physical condition much better than at time of last attack. When first seen had had thirteen convulsions; temperature 100° F., pulse no. Given coninae hydrobrom., gr. y^; slept until evening without convulsions and was in good physical condition; takes nourishment this morning, and was able to be about the ward on the following day. Case 10. — Male, aged 46; family history shows a predisposition to nervous disease; duration of epilepsy unknown; has a history of syphilis twenty years ago, but there is no indication of cerebral disease or that his convulsions are not true epilepsy. At the time of his attack he had had no convulsions for several months. On De- cember 16,1890, had three fits in the afternoon,, followed by seven in the evening without physi- cal failure. At 9 p.m. given coninse hydrobrom., gr. jf^j,; slept during the night without recur- rence of the fits. At 8 A.M. convulsions again occurred the same in character as before. Given chloral, grs. xxx, and potass, bromide, grs. 60, by stomach, without effect, also morph. sulph.,. gr. y^, and atropias sulph., gr. -^-^, with the same negative effect; at 11 p.m., coninas hydrobrom., gr. ^'d, with an immediate cessation of the con- vulsions. Patient rapidly improved, and in two> days was in his usual health. Case II. — Male, aged 45; 'family and previous 41 history unknown; has had previous attacks of status epilepticus, all having two points in com- mon, viz.: I. The large number of fits and their rapid occurrence, and 2, a state of secondary consciousness following such attacks in which the patient was greatly excited and very brutal; violent to any one who came near him. Physi- cal condition good; has had three fits in the last three months. On May 10, at 4 p.m., he had a severe convulsion, followed by others with inter- vals of about two minutes between them. At 4:20 he was etherized, after taking chloral hyd., grs. XXX, and potass, bromide, 3 i. On coming out of the anaesthetic, no convulsions occurred until 5:30 P.M. At 6 he was given coninae hy- drobrom., gr. y-J^. Slept during the night with- out convulsions. No attack followed this, and the man rapidly returned to his usual condition. The highest temperature during this attack was 104° F., pulse no. Case 12. — Same patient as Case 11. Physical condition impaired; no convulsions for several weeks. September 30: had twenty-three fits be- tween II A.M. and 12:30 P.M. Given coninse hydrobrom., gr. j-^-j. Convulsions ceased. Slept until 7 p» M., when the convulsions again com- menced; coninae repeated with same good result. October i, had several severe convulsions, fol- lowed by unconsciousness, stertorous breathing and right-sided hemiplegia. After being in this condition for about fifteen hours, death occurred. Temperature in this case ranged between 103° on 42 the first day of the attack and 107" at time of death. Such are the histories of twelve attacks of status epilepticus. Of the twenty cases which have come under our care, four were examined post-mortem. These examinations showed certain points common to all: i. A lack of symmetry in the two hemispheres, which is so often found in epi- leptics; 2, an inequality in the weight of the two hemispheres, also quite common in epilep- tics; 3, more or less extensive decortication; 4, intense engorgement of the brain and its mem- branes — the sinuses were filled with blood, the vessels of both the dura and pia were distended, the brain on section showed the puncta vasculosa to a marked degree; 5, in all four cases, and es- pecially marked in two, serous efiusion into the ventricles and arachnoid space. In one of the cases there was softening of the first and second temporo-sphenoidal convolutions on the right side. In another, which showed all the symptoms of apoplexy toward the end of the attack, a large haemorrhage from the middle cere- bral artery on the left side was found. In a third case, in which death occurred in- stantly and during a convulsion, a small haemor- rhage was found in the medulla. In none of these four cases was the cause of the status epilepticus found, and in only two was there evidence of the immediate cause of death. 43 The others, in all probability, died from the ex- haustion consequent upon the convulsions. The prognosis of status epilepticus is very un- favorable, the mortality being estimated at fifty per cent. The violence and frequency of the convulsions; the high temperature; the rapid, weak and irregular pulse; the consequent coma- tose condition, with its accompanying extreme depression, are all factors of such grave import that the outlook in most cases is very serious. Besides this, we must take into consideration the mechanical action brought into play, viz., the intense and powerful contractions of the muscles during a convulsion, which by exerting an irre- sistible pressure on the vessels, force the blood into the cerebral vessels, thus producing the great engorgement, with imminent liability to cerebral haemorrhage. Even though the individual passes safely through the status, hemiplegia often results, leaving him in a weak and helpless condition, and totally unable to withstand a second attack. The three most probable modes of death are: I, exhaustion; 2, from cerebral haemorrhage; 3, from serous effusion. Tredtment. — In a condition like status epilep- ticus, where the life of the individual may be de- stroyed in a few hours, any measure which will abort the attack is of the greatest importance. Our treatment must be chiefly symptomatic, at least until more is known of the pathological condition than we know at present. There are 44 two important indications for treatment which must be met in each case: i. To bring the con- vulsive period to an end as quickly as possible, and 2, to sustain the life of the individual through the stupid or excited period which may follow the attack. I. In order to meet the first indication for treatment, a large number of drugs have been tried, with a view of depressing the motor cen- tres of the cerebrum or cord, or of paralyzing the efierent nerves, or all of these, and thus pre- venting a fatal termination, either by diminish- ing the number of convulsions, making them less severe, or preventing them altogether. Among the therapeutic measures suggested to fulfill this indication, we shall consider only those with which we have had personal experi- ence in our own cases. These include the fol- lowing: Ether, chloroform, chloral hydrate, bro- mide of potassium, nitrite of amyl, sulphate of morphine, sulphate of atropine, hydrobromate of hyoscine, salicylate of physostigmine, and hy- drobromate of Conine. Ether and chloroform are given with the pur- pose of itr mediately stopping the convulsions by paralysis of the motor centres of the cerebrum and complete muscular relaxation. However successful these may be in the con- vulsions of Jacksonian epilepsy, in our experi- ence in rases of idiopathic status epilepticus they are but temporary measures, the convulsions ceasing only when the point of surgical anaes- 45 thesia has been reached, and coming on again before the patient has regained consciousness. They are of great use, however, in preventing the convulsions when exhaustion is imminent, while waiting for some other agent to act. Either may be used; but ip a case where the heart and respiration are already in a weakened condition, ether would be the safer. Chloral hydrate by the rectum has succeeded in some cases, but has more often failed. In giving this drug, it has been the custom to keep the patient under an anaesthetic during its absorp- tion, giving grs. xxx, and repeating it in an hour if necessary. Although acting as a de- pressant of the spinal cord and brain, yet the amounts which can be given with safety are usually too small to produce the desired effect. We have not used it hypodermically, but it seems probable that used in this manner the re- sults would be much better. Bromide of potassium has been given in sev- eral cases in combination with chloral hydrate, but without any good results. If, as in several of our cases, status epilepticus follows a course of bromide treatment, very little could be ex- pected from it, and indeed in any case, its action is so slow that but little could be hoped for from its use. In the few cases in which we have tried it, it has been given in doses of 3i-.^ii. Nitrite of amyl is highly recommended by some authors; but repeated trials have failed to establish its value. It has been given by inha- 46 lation, "L x, repeated at intervals; Although undoubtedly useful in preventing an impending convulsion of ordinary epilepsy, it has proved of but little value in the cases of status epilepticus in this hospital. Sulphate of morphine has succeeded in one case in which gr.^ was given hypodermically during ether anaesthesia; but in several other cases in which it was used it failed to change the course of the attack in any appreciable way, although given in doses of gr. }i—%, hypodermically. Sulphate of atropine, in any safe dose, acts strongly upon the cardiac and respiratory centres and upon the pneumogastric nerve, but very slightly upon the motor nerves of voluntary mus- cles. Carried further than this, it stimulates the cardiac sympathetic and paralyzes the pneu- mogastric, and in consequence there results a rapid heart failure. For this reason it is impos- sible to stop the convulsions without cardiac failure. Its immediate effect has been good by its stimulating action on the vagus and the re- sultant improvement in the character of the res- piration and circulation. Although it has been used with a view to stopping the convulsions, it is of more value in the second stage of neurosis. Hydrobromateof hyoscine, if given in sufficient amount hypodermically, produces almost imme- diate sleep, affects the motor tract of the spinal cord and cerebral cortex, and in a case in which its use is not contraindicated by weakness of the heart or respiration, its employment promises 47 good results. In the cases in which it has been used, the convulsions have quickly ceased, the heart's action has been slightly depressed after a short time, the respirations have been more fre- quent and less full, and sleep has followed, last- ing from two to eight hours, with a recurrence of the convulsions on awakening, and an improve- ment has occurred in the patient's condition. Although hyoscine has failed to bring the at- tack to an end in any of these cases, yet the rest and freedom from convulsions for several hours, with the resulting improvement in the bodily condition, would indicate its use as a temporary measure. It has been given in doses of gr. -j\j- ttssj hypodermically, its success in acute mania when given by this method, and its almost com- plete failure when given by the stomach, suggest- ing a similar result in status epilepticus. Salicylate of physostigmine, gr. -ji^, was given in one case with a view of depressing the cord sufficiently to stop the convulsions, but without success. Hydrobromate of conine was first used in a case in which most of the other measures in this list had failed, and its use was followed by an almost immediate cessation of the convulsions. Its action is from the periphery, extending to- ward the centre, the motor nerves being chiefly affected, the sensory nerves remaining almost un- changed. When a case in which it has been given is carefully watched, the following results are noticed: i. Weakening of the convulsive 48 movements, beginning at the lower extremities, and extending upward over the trunk and upper extremities, and last the head and face, with finally a complete cessation of the movements if a sufficient amount has been given; 2, slight di- lation of the pupils and ptosis; 3, some impair- ment of general sensibility; 4, heart slow and full, respiration slow and labored; 5, combined with sulphate of morphia, sleep follows, lasting several hours; 6, if the convulsions are to return, as the influence of the drug is lost, fibrillary con- tractions, beginning above and passing dowuT ward — that is, in the opposite direction from what they ceased — and finally the general con- vulsions are reestablished. This drug has been given in small doses, gr. -rffT-^V. hypodermically, and. repeated as often as indicated, the adminis- tration being guided by the character of the res- piration. It has usually been combined with sulphate of morphine to produce sleep, and sul- phate of atropine to act as a stimulant to the respiratory and circulatory organs, and also at times with digitalin and hyoscine. Only two of the cases in which it has been used have termin- ated unfavorably. In the first it stopped the convulsions; but they recurred, and cerebral haemorrhage complicated the case. In the second case it was given, as were all the drugs mentioned, the only measures attended with any success be- ing the administration of ether and chloroform, until there was complete muscular relaxation; and in this case the patient died suddenly, while 49 in a fit, from haemorrhage into the medulla. In several of the cases, conine and a small amount of morphine have been the only drugs used. Although it failed to control the convulsions in one case, yet it has been the most successful method of treatment tried, and its results encour- age us to believe that it will succeed in the ma- jority of cases of status epilepticus. 2. The exhaustion of the patient gives the second indication for treatment. In almost every case of status epilepticus, before the convulsions can be controlled there are evidences of physical failure; the pulse is rapid and weak, the respira- tion shallow and increased in rapidity, the tem- perature raised several degrees above normal, and a profuse perspiration covers the body, all of which call for immediate treatment in order to carry the patient through the dangerous period. The condition of the patient usually prevents the administration of food or medicine by the mouth, although if introduced into the stomach they will be retained. To fulfill this indication, we have introduced two methods: i. The hypodermic use of such agents as atropine, digitalin, spt.frumenti and quinine sulph. ; and 2, the introduction of milk, eggs and stimulants into the stomach by means of the nasal and stomach tubes, on account of the inability to swallow; artificial introduction of food into the stomach being especially called for in cases in which the stupid or excited periods are of several days' duration. 50 The conclusions drawn from this paper are as follows: 1. On account of its association with epikpsy, status epilepticus should not be considered a dis- tinct disease, but merely a climax of the neurosis, 2. It consists of two stages: i. A convulsive, and 2, a comatose, though the latter is some- times replaced by a period of maniacal excite- ment. 3. That there is no demonstrable lesion causa- tive of the status. 4. That the prognosis is unfavorable. 5. That the treatment is in a measure symp- tomatic, but considerable reliance can be placed upon the hypodermic use of the hydrobromates- of hyoscine or conine combined with the sulphate of morphine. FUNCTIONAL BRAIN DEGENERACY. BY J. T. SEARCY, M.D., OF TDSCALOOSij ALA. It is interesting to notice how much we are given to the habit of grading and estimating oth- ers in society. We are continually engaged in this kind of work, and we consider the opinions we have of our acquaintances and associates as very valuable items of information. So intuitive and instinctive is this kind of work that we do it unconsciously, as it were ; and as soon as we make an acquaintance, we find ourselves silently estimating and classifying him. The two particulars in which we generally con- sider it very important to estimate others are, first, their intellectual ability ; and secondly, their ethical sense. We call these ' ' mental and moral qualities," and recognize that they are more or less distinct and separate. In common with all other living beings, man lives in competitive life ; and so fundamental and continuous, from the earliest existence of life in the world, has been the necessity of alertness 52 and observation in order to survival and continu- ance, that man, in common with all other sen- tient beings, has acquired a constant sense of in- security on account of rivalry. We are all born with an instinctive knowledge of this fact. It haunts us from our earliest consciousness, and it follows us all through life. By highly advanced and improved brain capacity, and by suppression of rival species, man has so widened the distance between himself and lower grades that, compar- atively, he recognizes little danger from that di- rection. His principal rival is his fellow-man. It is this instinctive sense of insecurity on ac- count of rivalry, that begets the instinctive habit in us of grading and estimating our fellows. We wish to know at once how formidable a competitor our new acquaintance will prove, hence we promptly grade him in intellectual ability ; and we wish to know whether he will conduct his competitions or associations with us in accordance with established and advanced rules of decorum and propriety — hence, with equal promptness, we grade him in ethical sense. By the long progress of practice, we have be- come exceedingly expert in this kind of work. Some boast they can frame an opinion from as slender a foundation as expression of face, the cut of the eye, the step on the pavement, the iandwriting, the tone of voice, or style of dress. Of course such expressions are exaggerations, still they show how adept we have become, and how much we value such information. 53 As we estimate men in these particulars, we grade them into types, from the lowest savage, who is both very ignorant and very immoral, to the highest civilized, who is both highly intelli- gent and highly moral. Between these extremes there is every conceivable grade, variety and type. In the gradual rise of man from the state of savagery to that of civilization, his steady prog- ress is occasioned by and marked by gradual im- provement in both these particulars. There is a steady improvement in him of intelligence, and a steady improvement in him of ethical sense. We readily recognize that the person who suc- ceeds and excels is the intelligent one. He sur- passes others in the competitions of active soci- ety. Intelligence is very plainly a double quali- fication. I would divide it into two parts : the inherent brain- ability of the person to think — intell igoncc , and the acquisitions he has made by thinking — knowledge. . Ability to think is by far the most important, and whatever tends to im- prove or lower this qualification of the person tends to raise or lower his amount of knowledge, and his chances for success in the world. The person with a high order of brain capacity can and does acquire knowledge as the occasion re- quires. By intelligence, therefore, I mean ca- pacity to think and knowledge combined. In the slow and gradual advance of man, through generations, from a savage condition to a highly civilized one, it is the gradually increas- 54 ing necessities occasioned by the competitions of a more and more complex society, that force him, in order to avoid suppression and elimination, to steadily improve his brain ability to think. The elimination of those least fit in brain capacity, and the survival of the more fit, is the natural method of gradual improvement in humanity. The original source of improved capacity and of accumulated knowledge, that is, of intelligence in the world, is therefore competitive life, and it is very easy to trace back all varieties of intel- lectual ability to the gradually acquired brain capacity that has been the result of the struggles for existence and for ascendency, carried into the more and more complex and refined methods and habits of advanced society. As society advances, we notice that not only is there an advance in intellectual qualifications — in ability to think — but almost pari passu with this line of capacity, there also is acquired an- other habit of thought, namely, an ethical sense. As soon as human society begins to grow com- plex, then arises the public necessity that the competitions of its membership shall be regulated. Families, communities and races soon become themselves aggregated into wholes, individual- ized, because they become competitors with other families, communities and races, and public good demands that the internal rivalries of their mem- bers shall be so harmonized and so adjusted to each other as to subserve general welfare. Pub- lic safety demands ethical observances, and a 55 large proportion of the efforts and powers of so- ciety are spent in the inculcation of rules of con- ■duct that relate to public good ; in this the rules, laws and government of society, with the moral sentiment and public opinion that back them, as men become intelligent, become of a higher and higher grade, until those that harmonize and adjust the associations and competitions of the most advanced society are reached. For these reasons the individual member of advancing society, besides becoming by compet- itive practice more and more capable intellectu- ally, at the same time, becomes more and more habituated in the performance of ethical obser- -vances. The habit of adjusting conduct ethi- ■cally, that is, according to established rules of society and the rights and wishes of others, be- comes more and more fixed as a trait of character. My object in this sort of observation is to draw attention to the fact that the tests by which we grade and classify our fellows — their intellectual and ethical abilities — are the results of the grad- ^lal practice and exercise to which men have been submitted through generations on generations of advancing, developing existence. A most advanced man, therefore, is he who las such intellectual ability to think, that he can so understand the complexities of advanced soci- ety as to be able to formulate arid promulgate the highest and best rules of conduct, and has such an ethical habit inherent in him that he holds 56 true by an educated conscience in the observance of tbem. The highest type of man, in short, is he who has the highest intellectual sense, coupled with the highest ethical sense. Brain strength, like muscle strength, is the result of previous practice and exercise. All- round ability is the result of all-round work, and specialized accomplishments are the results of special kinds of practice. In brain-work, as in muscle-work, the exercise, in order to be im- proving, must reach the degree of being effort. Unless there is a constant sense of effort in mus- cle-work, muscle strength does not improve ; the same is the case in brain- work. Brain work is therefore necessary in order to continue brain ca- pacity; and in order to raise the level of capacity, increased effort is necessary. Previous activity alone produces capacity; continued activity alone continues capacity ; and increased activity alone increases capacity. The previous activity that produces capacity is either ancestral or individual. In biological descent the individual only represents one link in a chain of activity. ^The person gets his abil- ity from the line of his ancestry — receives it at a certain level, and maintains or raises it solely by his own activity. Heredity means no more than the continuance in the line of the habits of ac- tion established in the ancest«» Of the two elements of intelligence which I have mentioned, viz.: capacity to think and knowledge, capacity 57 is inherited, knowledge is not. Knowledge has to be acquired, but by far the greater part and the best part of the capacity is inherited from ancestry, and is the result of previous ancestral brain exercise. Brain abilities are not constant qualities; they vary in the life of the person and in the line of descent according to habits of thought. Prac- tice alone produces ; practice alone continues ; and increased practice alone increases brain abil- ities. According to these rules, our high-grade intel- lectual person is the result of previous ancestral and individual intellectual practice, and is, at the same time, ethical to a high degree, because of high-grade ancestral and individual ethical practice. The highest type of man, the one highly intelligent and highly ethical, is solely the result of the practice of both these kinds of brain work, and can occur only in that sort of advanced society which has been active and in- dustrious, so as to have necessitated brain activ- ity on the part of its members, and in that sort of society where the study and observance of high ethical rules are a constant practice. No community, no matter how civilized, is uniform in its membership ; we can find low types of men everywhere. In the most advanced society its membership will grade from the high- est type — highly intelligent and highly ethical, to the lowest — very ignorant and very immoral. Brain abilities are not constant qualities. There 58 is no constant level of capacity; it rises and falls according as the brain is practiced or not prac- ticed. While, therefore, we may state that activity improves capacity, we can with equal accuracy assert that inactivity lowers capacity. Much — probably most — of tbe impaired or lowered brain capacity in society comes from brain idleness. Functional capacity begins at once to lapse if functional brain activity is abated. We witness this on all sides : whatever conditions, due to wealth or poverty, conduce to lessen functional brain work, tend to impair intellectual capacity to think, and the ethical sense to do right. In the idle wealthy ranks and in the idle poor ranks we find most degeneracy. The active, indus- trious middle class carry the main current of improvement. Improvement is only found where there is activity, and degeneracy is always an accompaniment to idleness. Society sloughs off at its two inactive idle extremes. , If you study the conditions that lead to brain work on the one hand, and those that lead to a cessation from brain work on the other, you have much of the secret of improvement and of degeneracy, in the individual, in the family, in the community, and in the nation. There is in this way a very ready, because a very physiological, explanation of much that otherwise is strange and diflBcnlt to understand. Families lapse from wealthy posi- tions into poverty in the course of one or two generations, because the necessities for brain 59 ■work having been removed, degeneracy comes ■with the condition of inactivity. Races and nations readily follo^w the same course. A very large proportion of the incompetent and the ■vicious elements of society is made up of the lapsed members — of those whose lines of capacity point downward. Almost every family can be said to be tending towards survival or towards elimination, and the cause of their tendency can be readily learned by observing whether their brain habits are active or inactive. The competitions of active, industrious society determine the levels of its members. The incom- petent poor classes become poorer, occupy unfa- ■vorable and unhealthy positions, and eliminate rapidly; while wealth induces idleness and de- generacy, and consequent inability to add to, or to even hold to the property that parental or "ancestral capacity may have provided ; in time the rich disappear, or ' ' the top rail goes to the bottom, " to be eliminated in the poor ranks. In •our rapidly changing American society, it is ■very common to find in the second or third gen- eration the relics of once wealthy families, unable now to compete successfully for a living because of degeneracy in intellectual ability, and with ethical habits alongside the very lowest. I have probably said enough to warrant the statement that brain activity alone induces brain capacity, and that brain inactivity induces brain incapacity. In this observation, we notice that there is 6o only one way of improving capacity, namely, by activity; but when we turn to the converse prop- osition, we recognize there are several ways of lowering it. Inactivity, I have said, induces most of the incompetency, but it does not pro- duce all. It does it by impairing the brain's ability; but the brain's ability is also lowered by whatever else, in any other way, impairs or in- jures its structure. Functional capacity depends upon structural integrity. Any defect, injury or disease of the brain lowers its capacity ; and we judge the pathological disability by the same tests that we use in grading physiological disa- bility; that is, we witness there is always more or less impairment in intellectual and ethical capacities in brains pathologically impaired. In all our insane asylums we find persons who once were graded high in intellectual and ethical abilities, now sadly lowered in both these quali- fications. We estimate the insane by the same tests we estimate the sane. In a large majority of cases the decision is easily made. It is only in those cases when the insane degree of disabil- ity is not yet quite reached, but is approaching, and it is necessary to anticipate it, and in those cases when the disability is transient and ques- tionable, that the expert is required. The methods of brain degeneracy I have thus far mentioned are, foremost and principally, brain idleness, and next, those pathological conditions which are the results of disease, injury or defect; but there are other causes at work in society, by 6i some not recognized or classed as pathological, which question I won't stop to discuss ; and these causes, in my opinion, are very potent — probably, next to brain idleness, the most potent in modern brain degeneracy. I allude to the widespread and abundant use of brain drugs, the principal one of which is alcohol. Next to brain inactivity, I believe brain injury with drugs, especially alcohol, produces most modern brain degeneracy. In proportion as the amount of alcohol in the circulation is increased, in addi- tion to a lessening of sensibility, we witness a gradual lessening of intellectual ability. This declines through descending stages from the condition in which we describe the person as a "little off," intellectual capacity slightly low- ered, judgment and accuracy of thought slightly defective, to that condition where there is entire loss, and the man is a temporary dement. In proportion, too, to the amount of alcohol taken, we witness ethical ability to be lowered, and the cerebral disability in this particular will be exhibited in descending stages, reaching from slight loss of the sense of propriety and decorum to that condition in which the person is such a nuisance, or is so degenerous to his associates, that he reaches the degree of temporary mania, and has to be restrained. These effects of alcohol upon the brain will vary in different persons. Callous brains exhibit impairment to a degree than more sensitive ones; low grade brains reach the savage level sooner 62 than highly advanced ones, and defective, injured or diseased brains exhibit their failures in the lines of their deficiences. The length of time, also, that the alcohol use is continued increases the degree of disability. A single debauch can be readily recovered from, but long-continued use leaves such impairment that only in rare cases does complete recovery- ensue. Sometimes we have these conditions all super- vene in the same person; that is, we have a con- siderable quantity taken by a brain already weak or defective, and the drinking is continued a long- time. This is the case with the majority of those whom we call inebriates. In a majority of cases the brain of the inebriate is originally low- grade, and nothing could be done to more effectually lower its capacity still further. But it matters not whether there is original weakness or not, a sufficient quantity, long continued, will bring^ down, in intellectual and ethical capacity, the most advanced brain to the level of the lowest. Whenever an idle, incompetent brain is rendered still more incompetent by the chemical effect of a drug, degeneracy and the consequent elimina- tion of the person and his lines of descent is rapid indeed ; and this happens not nearly so much by the injury to other structures and organs of the body, so as to induce death direct- ly, but, because the injury to the brain places the person, by his loss of intellectual and ethical capacity, in unfavorable, poor and vicious sur- 63 roundings and indirectly causes the elimination of himself and his line. Brain injury with drugs produces a great deal of modern brain degeneracy, and, in connection with brain idleness, is an exceedingly rapid elim- inator in society. The popular and indiscreet use of alcohol, nicotine, opium, and similar drugs, is a very potent factor in modern degen- eracy. The application of the above principles to the explanation, on the one hand, of success and sur- vival, and on the other, of failure and elimina- tion, is very interesting. We are very apt to lose sight of the rapid rate of human elimination. What is a possible or normal rate of increase is never reached by any people; causes of elimination are constantly at work to keep the increase below the normal rate. If every human female who is born reached adult life, and bore a reasonable number of children, directly, there would not be standing-room in the world. The grade of brain ability, as I have said, is the factor that, more than anything else, determines a person's position in the world ; and a physiological consideration of the causes that lead to increase or decrease of these faculties is seldom heard ; yet it is a most rational way of dealing with the subject. Before I close, I think it will prove interesting if I apply some of the physiological principles I have been enumerating to a broader field, and as briefly as possible show how the rise and fall of 64 races run on the same principles that individu- als rise and fall in society. A race is an aggregate of similar individuals — or, more properly, of similar lines of descent. What determines the grade of a race is the level of the aggregate capacity of these lines. The centre of the aggregate potentiality of the race, in the progress of its social dynamics upwards or downwards, varies as an individual's ; with, of course, less sudden variations, because of the overlapping of generations — still it never, or sel- dom long, remains at the same level. Just as much as with the individual, it takes continuous activity to keep up capacity in the race, and in- activity lowers capacity. We often hear it stated that a race or nation degenerated because they forgot the instructions or accumulated experiences of their forefathers. The forgetting or the not heeding had very little to do with it. The records of the accumulated experiences of a race's previous history are al- ways abundant, and the alarmed, but gradually thinning ranks of their leaders are continually pro- claiming and preaching and teaching them; but the secret of their gradual decline in prestige and power, and comparative influence among other races, lies, as is often the case with the individual in society, in gradual abatement and stopping of previous brain industry and activity. An active race soon reaches a stage of comparative excel- lence and wealth and power, so as to be relieved of the immediate competitive necessity for con- 65 tinued exertion. When this is the case, it is just as much " human nature " in the aggregate of individuals, as in the single individual, to stop further exertion and exercise. The ancient Semitic races, who once inhabited western Asia and ancient Egypt, and who long antedated the Aryans of Europe in civilization, grew powerful first and then rich, stopped activity and declined in excellence. It matters not whether you locate the origin of the Aryan races in the centre of Asia or in cen- tral Europe, as is more recently advocated ; when first known, they were an active, combative, com- petitive people in Europe, considered by the an- cient Assyrians, Phonicians and Egyptians as barbarous and semi-civilized. Those Aryans who occupied the peninsulas of ancient Greece and Italy, caught up first the civilizations of Asia and Egypt, because they were nearest to them. An active, progressive, advancing race, like the in- dividual, is acquisitive of knowledge as well as wealth, They learned from their advanced neigh- bors, and by activity themselves became powerful in knowledge and resources ; then conquered and plundered the old Semitics, and rose to be the excellent and leading races of Greece and Rome. Greece, the one nearest to the Semitics, improved first and declined first. In time, the same physiological processes took place with the people of Greece and Rome. They waxed "comparatively excellent, the necessity for further exertion was relieved, and they turned 66 the pinnacle of excellence and began the decline of the other side because of brain degeneracy— not because they had not the accumulated wisdom and wealth of the world, but because the aggre- gate of their brain capacity lowered in level for the want of the continued brain practice and ex- ercise necessary to keep them up. The aggregate capacity of the nation to think and to act ethically declined. Defended by the mountains to the north of them from their kindred Aryan races of central Europe, and having thoroughly demolished the races south of them, the Empire of Greece, and of Rome particularly, had abundant time of idle- ness and inaction to become thoroughly degener- ate ; so, when the hordes from the north poured over the mountains, these empires sank easily. The darkness that followed the submergence of these ancient civilizations, was for a time so com- plete and dense, because the Goths and Vandals were themselves not able to appreciate and appro- priate the civilizations that they destroyed. They conquered Rome too soon, before they were them- selves ready for it. "The dark ages " were the result ; and if it had not been for the Arabs in Alexandria, who worked round the coast of North Africa, and into Spain, keeping up the lamp of civilization, with the help of the Jews and Greeks they imported to teach them, the light of civilization would have been almost to- tally submerged. The Moors of Spain took event- ually the same old routine course, before the 67 gradually improving Aryans of central Europe ; in their turn became rich, inactive, and disap- peared. Those Aryan nations of Europe who to- day hold their positions of highest excellence in the world, have solely reached their eminence by their improved brain abilities — the result of gen- erations on generations of advancing brain prac- tice. A semi-civilized king of Asia or North Africa may think in his visit to London, if he had all the wealth and vast material resources of Eng- land transported to his country, his would be a nation equally as great. Nothing is more mis- taken. The only way for his people to reach the proud eminence of excellence of the British Is- landers, is for them to have gone through the same long processes of industrious, persevering, high- ordered brain practice, similar to that through which these people have passed. It is the work of generations, and cannot be donated in a day. In this connection, it is interesting to notice to what degrees and at what levels the different savage, barbarous, semi-civilized races of the world have appropriated the civilization of Eu- rope, as it has, in the intercommunication of modern commerce and travel, and by teachers, been conveyed to them. There are hundreds of illustrations in the world of the fact, that a low grade race accepts and runs advanced civilization just at the level of their inherent ability. A 68 singular observation, connected with this fact — often some test of competitive ability, in war for instance — is necessary to show the superiority of the advanced race to the inferior one, so as to make it ready to appreciate and learn. The inhabitants of the Pacific and Indian Ocean Islands are good illustrations of these principles. Those inhabitants, who by ethno- logical tests show themselves to be descendants of the more advanced races of Eastern Asia, have appropriated civilization at more rapid rates than those types similar to the races of Southern Asia and Africa. At one extreme, we may men- tian the notable examples of the Sandwich Is- landers and the Hoovas of Madagascar, both of Eastern Asia types ; and at the other extreme, the Andaman Islanders and the inhabitants of Tasmania and New Zealand, of African type. Of the Eastern Asiatics, the Japanese exhibit, in all particulars, more activity, and consequent- ly more progressiveness, than tne Chinese, the Malays or Burmah races. The ancient civiliza- tions of these races were among the first in the world, but, in the case of the Chinese par- ticularly, the rigidity of too crowded a popula- lation suppresses improving activity. I could take the range of the world to illus- trate these principles, but have not the time. It may prove more instructive to come closer home. In America we have three very distinct types ■of men^the Indians, the Africans and the Euro- pean whites. 69 It is a remarkable fact, low-grade races melt away and disappear in the presence of the more advanced ones. In modem times they are not exterminated by war; very few are killed out ; still, they rapidly disappear. Whole tribes con- tiguous to the English and European colonies in Africa have disappeared, and in Australia they are melting away like our Indians. The last Tasmanian has been said recently to have died, and- the English government, out of sym- pathy, has recently been gathering together the few natives of New Zealand as ethnological curi- osities. When an advanced race, as the Europeans in America, for instance, occupy the country of a low-grade race, and attempted to force them to assume the methods of civilization, the change of the brain habits of thought is too sudden for the inferior race to assume. In civilized society, as I have shown, persons of low intellectual and ethical abilities occupy the eliminating grades. To force an inferior people, never practiced or trained in the habits of industrial competitive thought, into the ranks of a civilized race, is equivalent to forcing them into the eliminating grade of that society. The Indians have no- where been able to enter into industrial competi- tive life with the Europeans and survive, but, wherever it is attempted, they simply asstmie the position they are capable of taking ; in common language, they become poor and vicious, and are eliminated along with the eliminating whites. 70 The vice of civilized society, to which they take with avidity, is alcohol drinking ; and nothing contributes more rapidly to increase their incom- petency and viciousness. As with low- grade individuals in advanced society, alcohol is a most rapid eliminator of low-grade races. The general government, in its management of the Indians, finds it has to prevent their access to alcohol, and the missionary among them, in his endeavors to arrest the current of their downward degeneracy, finds his efforts futile, if drink is allowed. The elimination of the Indian races is due principally to these causes; first, it is impos- sible for the Indian to assume so suddenly the habits of civilized thought which are necessary in order to prevent elimination. For the same reasons the hyena and eagle in confinement be- come unprolific and defective in descent, so does the Indian ; and he often adds rapidly to his degeneracy by drink habits. When the Spaniards discovered America, they set out at once to enslaving the Indians. They did this first on a large scale in the West Indies, by the hundreds of thousands. The sudden change of brain habits was so severe and extreme that these races exterminated excessively. To- day there is hardly a relic to be found. They proved so unsuitable for slaves, the Spaniards had soon to import Africans. The Africans, from the remotest antiquity, have been preyed upon by other races for slaves. From the eastern side of the continent, next to 71 Asia, they have been raided most, and are still so to-day, On the west coast, whence America received her slaves, they had been before that for thousands of years unmolested and least mixed with Asiatics. They had, among them- selves, varied to some extent into grades, accord- ing; to activity, climate and surroundings. The lowest types of men in the world were found among them, while some were somewhat ad- vanced. The characteristic that rendered them suitable for slaves was, they were passive in dis- position, and would bear pressure and moulding. After African slavery had begun in the West Indies, it was soon extended to the continent. The two hundred years that slavery continued in the United States under its extreme artificial conditions, it exerted powerful modifying influ- ences upon both the Africans and their European masters. The Africans, for four or five generations, un- derwent forcible practice in very much more advanced brain activity than they ever performed before. The African, originally, with very mod- erate exceptions an abject savage, was rapidly made to assume the language, dress, customs and conventionalities of the whites, and practice their habits of thought as far as he was able to understand and imitate them. Each one may be said to have had a private tutor of his own. It is true, the master's interests directed and largely controlled their brain practice; selfishly, in many cases, he directed his slave's habits and labors ; 72 still, involved in all such work, was brain exer- cise of a higher order than the African ever prac- ticed before. His muscles were exercised, hi& food directed, and his improved sanitary condi- tion brought his average general health to a. higher level. At the time of their emancipation there could not, in my opinion, have been found in the world six millions of people, in a body, to- excel the American slaves in three essential par- ticulars — general healthfulness, prolificness, and sobriety. These excellences were the results of two or three hundred years of artificial selection and improvement. In brain work, higher intel- lectual and ethical practice and instruction was- the result of simple association with the whites, as well as the result of direct efibrts on the part of the whites to improve them. The. selfish in- terests of the whites dictated, probably, most of their efforts ; still, some were incited by the highest altruistic motives. Upon the whole, the American negro emerged from slavery improved above his original grade in intellectual and eth- ical capacities; and his was an example of more rapid advancement than has ever been witnessed before in such a type of people in such numbers. The national processes of improvement by- activity, and of deterioration by inactivity, had obtained to some extent among the tribes of Africa, which made slight variations in the types- imported as slaves, and probably still hold in the grades among them; but the artificial and forcible influences which obtained all during 73 slavery, by training, association and education, and are still continuing, in the efforts made to improve and govern them, together with mis- cegenation, have tended to advance some few lines toward comparative ability to compete, and toward continuance and survival; but the large majority are taking their natural level in the eliminating grades of society, and prove an incu- bus upon the country's progress. The race is certainly letting down in the three particulars in which they excelled — of healthfulness of sys- tem, of prolificness, and of sobriety. Among those, braced up by, and floating along with, the currents of activity established and maintained by the whites, most examples of improvement are found. But in these sections, where they are in large majorities, and left to their own ex- ertions, intellectual and ethical deterioration is very apparent. Statistics show very rapid elim- ination of them in the towns and cities, where competitions with the whites force them into most unfavorable surroundings. That the negro, in the South, is seen to fill the prisons, the police courts and the peniten- tiaries is an exhibition of a natural condition ; he is living under a civilization and a code of laws that he is not able himself to formulate or maintain. He fails ethically, as well as intel- lectually, in larger proportions than the whites, because he is not as capable in maintenance of the kind of activity his surroundings demand. 74 But I have not the time to pursue this question further. It- is only necessary, generally, in the case of the European whites in this country, to apply these pri&ciples, to have ready solutions of the changes going on in our diflFerent communities and in our national society. The wholesale im- portation of the degenerating classes of the old world is having a most deteriorating influence tipon our national, intellectual and ethical level. As the good of society feels the fluctuations in the ethical currents first and most, we can see the deterioration, even in high places, due to this influence. Brains degenerated in capabili- ties, by the rigidity of the strata in European society, which prevents all kinds of activity, •except muscle drudgery, are filling our land faster than the three or four generations neces- sary to elevate them can counteract. We have not yet invented a cerebral dynamometer by -which we can quickly test a man's intellectual ability and his ethical strength. Such a test, "however, is sadly needed. Persons who fall below A certain level in these two essential qualifica- tions ought not to be allowed to enter the coun- try, no matter whether they haU from Europe, Asia or Africa. In conclusion, I insist I have been on purely physiological and professional ground all the ^way in this discussion. The corrollaries I would 4iraw from it are: 75 1. Brain capacity is solely the result of ances- tral and individual brain practice. 2. The test of these qualifications are the grades of intellectual and ethical abilities, usu- ally determined by the level the individual, the family or the race occupies in competitive life. 3. Degeneracies of brain ability are occasioned by brain inactivity, which is the principal meth- od of deterioration ; but whatever injures the brain structure impairs intellectual and ethical ability, whether it be traumatism, disease or defect, or abuse with drugs. 4. A great field for the highest order of public sanitation is open in this direction, heretofore almost wholly unoccupied by our profession. In discussion Dr. Herdman, of Michigan, said: I, for one, feel like congratulating the -mem- bers of the Section upon the privilege of listen- ing to such a philosophical paper as has just been read. It seems to me to have presented topics eminently appropriate for consideration ' by this Section. It is a deplorable fact, disheart- ening oftentimes to the neurologist and alienist, that many of the diseases with which he has to deal in his daily practice are, in the individual, incurable ; but little can be done for them in one generation. The causes and influences that have been at work in bringing about the pathological change are inherited from the ancestor ; are the fruit of bad social customs, of imperfect methods of education. 76 The work of the neurologist, therefore, as a student of brain deterioration, carries him beyond the immediate to a study of remote causes, which are the chief factors oftentimes in producing the result in the individual he is called upon to treat. Upon us rests the responsibility of pointing out these far-reaching influences, and herein is the most encouraging field for the exercise of our talents as promoters of the welfare of humanity. It is true, as has been clearly set forth in the paper, that man, in his evolution to the point of greatest efl&ciency, can only attain that end by healthful exercise of every faculty. Man's con- stitution is a trinity composed oi physical, mental' and moral faculties. • The perfect man is the product of these three acting harmoniously and carried to the degree of their highest possible devslopment. They constitute a tripod on which the superstructure, when symmetrically built, rests securely. And in the process of develop- ment toward the perfect man no one of the three pillars, upon which the final result depends, can be ignored. To neglect the physical, the mental or the moral faculties of his nature ; to cultivate one at the expense of the other; to fail to observe the interdependence of the one upon the other, will produce a greater or less degree of deformity, and not the perfect man. The central nervous system is the organism upon which the develop- ment of these faculties depends, and by means of which they find expression. The growth of the normal structure and function go hand in 77 hand. What then, we should ask ourselves, are the causes, the influences at work in the race and in society; what are the conditions necessary for obtaining perfection in the harmonious develop- ment of man's threefold nature? These are legitimate subjects for the thought- ful consideration and research of every physician who attempts to enlighten his fellow- man as to the laws to which his nature is subjected, and the forces that afiect his well-being in its entire- ty. And such responsibility rests upon the neu- rologist and alienist, perhaps to a greater degree than upon any other class of practitioners of the healing art. In him do we expect to find a store- house of all truth, so far as discovered, which has a bearing upon the evolution or dissolution of man's brain. What then is the value of the discussion of this or that agent in the pharma- copoeia in some particular disease, as compared with a study of these principles, which underlie an entire class of pathological conditions ? There is at the present time a strong convic- tion among neurologists, which is shared by oth- ers in the medical profession and by thoughtful men and women among the laity as well, that the man addicted to the use of alcohol in excess is a sufierer from disease ; that his brain has under- gone functional, if not structural, change, which renders him as incapable of self-control as the idiotic or the insane, and that this condition of irresponsibility is not confined alone to those times when his blood is saturated with alcohol 78 from recent indulgence or debauch — but that during the intervals of drunkenness he is inca- pable of acting as a sane man, and should there- fore be dealt with, not as a criminal to be turned over to the police only in some fit of bacchana- lian excess, but is at all times, until pronounced cured by competent judges, a fit subject for the hospital or the asylum. This and other social problems of no less im- port and wide-reaching applications, come within the legitimate range of our purpose ; are rather the most vital questions for discussion by the members of this Section, and the paper which has just been read points out the road along which, as a company of specialists, we can do the greatest good to our fellow-men. Dr. Hughes said he desired to express his ap- preciation of the worth and excellence of the paper. He was glad to see papers of this kind brought before the Section. Formerly physio- logical psychology was a subject that emptied the room, but this to a great extent had been changed by Maudsley and Spencer. These wr ^' ers had attracted general medical attention. Pa- pers of this kind will do much to settle' psychical hygiene for both the individual and society. THE VIRILE AND OTHER NERVOUS REFLEXES. BY C; H. HUGHES, M.D., OF ST. LOUIS, PROFESSOR OF NEUROLOGY IN MARION-SIMS COLLEGE OF MEDI- CINE, HONORARY MEMBER OF THE BRITISH MEDICO- PSYCHOLOGICAL ASSOCIATION, ETC. In a previous communication on this subject {vide Alienist and Neurologist ior 'i&nn.airy, 1891), I have called attention to the fact that in a per- fectly healthy individual, whose spinal cord is entirely normal, especially in its genito- spinal center, placed supine on a couch without head- rest, nude about the loins, the sheath of the penis made tense by clasping the foreskin with the left index finger and thumb at about the place of the fraenum, and pulling it firmly toward the umbilicus, placing the middle, ring and little finger low down upon the dorsum of the virile organ, the dorsum or sides of the penis, near the perineal extremity, then sharply precussed, a quick and very sensible reflex motor response or retraction of the bulbo-cavernous portion will be felt to result from this sudden percussional im- 8o pressioD, like that which follows, though less pronounced, in the testicles, after sensory irrita- tion of the inner aspect of the thighs, and known as the cremasteric reflex, with this difference only, the cremasteric reflex is a sudden upward moyement of the testicle of the side irritated, while the virile reflex is a sudden downward jerk. While this reflex, like all reflexes with which I am familiar, is away from the irritating afferent impression, it is in marked contrast with the patellar tendon phenomenon in being away from the heart instead of toward it, as so many reflex movements are. It differs from the ordinary penile erection, and must not be mistaken for it (for it cannot properly be called an erection) in this respect, too, viz., that it is downward, and not upward, and proceeds always from a periph- eral and external irritation; whereas, erections more often proceed from direct central (cerebral) impression proceeding downward and outward. Its action corresponds to the oesophageal re- flex, or reflex for swallowing. This reflex symptom is of important clinical and physiological significance, as will later on be shown. I have called it the virile reflex, because I think, if properly sought for, it will be actively ■present in all healthy adult males with normal spinal cords ; at least, I have so found it in all. It is absent in infants, and feeble or absent in male children who have not attained the age of puberty. 8i A number of years ago I ventured the asser- tion that the absence of the cremasteric xeflex would be found of significance in the determiaa- tion of impaired virility from sexual excess or masturbation. This, subsequent experience has only confirmed. Now this new sign— the virile, the penis percussion reflex, or, as M. Ounanoff calls it, the bulbo cavernous reflex — present, im- paired or absent, gives us another valuable evi- dence of the vigor, impairment, loss or abeyance of the sexual powers in man. After prolonged excessive venery it becomes impaired or disappears, to return again with sexual recuperation. After excessive masturbation, long continued, with accompanying neurasthenia, I have found it impaired, but seldom entirely absent in young subjects. It is not impaired in masturbation when the habit has destroyed the sexual power. It disappears in some cases of chronic meconism, and becomes abeyant in long and beastly intoxi- cation, though often excitable in acute alcohol- ism. This subject needs further investigation. It is lowered and abeyant in the later stages of typhoid fever, and I have found it also in the moribund state. I have found it absent in old men who have acknowledged and sought treat- ment for entire virile incapacity. It is often, but by no means uniformly, found in sympathy with the other reflexes in spinal cord disease of the lumbo-dorsal spine, as the quadriceps extensor femoris tendon reflex, the 82 anal, vesical and cremasteric reflex, the Achilles reflex; ankle clonus, etc. This phenomenon may also be elicited by sud- denly jerking the foreskin after it has been made tense, or by pinching the theca of the penis when it is in this stretched condition. This reflex may be reinforced like the knee phenomenon, but by a difierent process, viz., the frictional excita- tion of the glans and body of the organ by means of a brush, or brushing it briskly with a piece of paper. It may also be evoked by electrical excitation, a kind of clonus sometimes appearing after this form of irritation. As I said in my first communication, some skill in palpation — a sort of tactus eruditus — is necessary in examin- ing for this sign, the characteristic jerking back of the bulbous urethra within the sheath of the penis being felt only when carefully sought for. It is not ordinarily to be seen. I have found the sign absent in cases like the following : Pupils unequal, patellar reflex exag- gerated, and other evidences of sclerose in plaques, with history of syphilis, and acknowl- edged feeble virility, and diagnosis by a compe- tent ophthalmologist of optic- atrophy. I believe it will be found to be quite generally absent when there is optic atrophy, unequal pupils, and other evidences of cerebral sclerosis, or multiple cere- bro-spinal disease of this nature. I have found this sign absent in the status epilepticus, but not necessarily modified in hemiplegia, and exag- gerated in cerebral paraplegia. 83 The following clinical records, made since my first report on this subject, add additional confir- mation to the significance of this sign : Case I. — Mr. J. B., aged 23, single, locomotive fireman, first presented himself for treatment at my office July 11, 1891, when I obtained the fol- lowing history : Some three years ago, in alight- ing from his locomotive running at the rate of 15 miles an hour, he sprained his back, but it did not give him much trouble at that time. About three weeks ago, while perspiring freely, he ' ' caught cold ' ' and the perspiration suddenly stopped — from this patient refers present trouble, though he had an attack of la grippe in Febru- ary, and about latter part of April, he noticed impairment of motion of right leg. Some four years ago he indulged in sexual intercourse to excess — ^upon one occasion, had connection seven times in twenty-four hours. He has had no in- clination for sexual intercourse lately, thinks he has had sexual desire but about a half dozen times during the past two years. Bowels constipated, for which he resorts fre- quently to purgatives. Had an attack of vertigo to day, and fell to the floor while in the act of yawning. Pulse (sitting) 66 ; upon slight exer- tion (walking about the room), pulse increases to 78. Right knee-jerk abnormal; R. quadriceps clonus marked up to origin of muscles — a slight tap below right patella (not suflBcient to produce patellar reflex), will cause quadriceps muscle to vibrate, R. knee response below normal, left 84 knee-jerk impaired, no quadriceps clonus. R. gastrocnemius reflex normal ; R. plantar and solar reflexes exaggerated, and clonus follows reflex excitation; plantar surface of right foot hypersesthetic. Flexion of right foot incomplete one- half, rotation impaired one-half, flexion and extension impaired about one-half. While sit- ting, he can only lift right leg and thigh about three-fourths as compared to left. Has head and«back ache. No spinal tenderness, tender over crest of right ilium and beneath ribs of right side. ^sthesiometric tests of finger tips give nor- mal results. Numbness of left great toe, but no abnormal sesthesiometric sign. Has slight right scrotal hernia ; has phimosis. Virile reflex impaired, extremely feeble, and elicited with difliculty. Patient put upon the following treatment : R. Quiniabisulphatis, drachm ij. Ext. nucis vomicae, gr. xij. Ergotine, scrup., ij. Ext. belladonnEe, Aloiu (Merck), aa gr. iij. Liq. potass, arseuitis, gtt. xv. Misce, et fiat cap.. No. xxxvj. Sig. One three times a day. R. Sodii bromidi, oz. iss. Aq. menth. pip., q. s. ad. oz. vj. Misce, solve, et Sig. Tablespoonful at night. Patient reported some three times at intervals of a week, and a marked improvement was ob- served. He then left on a trip, to return unless the improvement continued uninterruptedly, and 1 have not heard from him since. 85 Case 2. — Mr. Chas. B. H., 21, occupation far- mer, single, applied at my office for treatment August 15, 1891, and gave the following history: About a year ago, he slept on the damp ground for five successive nights, each morning he felt stiff, and head was very sore. As the effect of this, he was sick in bed with fever for a week or more, legs were paralyzed, bowels constipated, and urine retained — was catheterized several times. He was attended by two local physicians. Says he suifered severe pain during first three weeks of illness, and was troubled with erections. Patient's present condition is as follows : Pulse 90 (patient sitting) and full, temp. iod° Fah., appetite and digestion good, and sleeps well ; no erections at present. Some pain in lumbar and sacral region. Crosses right leg over the left with difficulty, cannot lift the left leg without the assistance of hands, cannot stand alone. Patellar tendon reflex is absent, virile reflex present, but impaired, cremasteric reflex normal, and has ab- dominal reflex. Has never had syphilis, or any zymotic disease. Patient placed upon the following treatment : R. Quiniae bisulphatis, drachm ij. Ext. nucis vomicae, gr. vj. Ext. ergotae, gr xxiv. Fowler's sol., gtt. xl. Misce. Tiat. cap. No. xxiv. Sig. Take 2 capsules three times a day — in the morning, after dinner, and at bedtime. 86 R. Sodii bromidi, oz. iss. Kalii iodidi, oz. ss. Syr. Hypophos. comp. (Fellows'), oz. iv. lyiq. pot. arsen., dr. j. Aq. merith. pip., ad., oz. vj. Misce. Solve, et Sig. Teaspoonful in the morning and 2 teaspoonfuls in the evening. I select and epitomize a few cases from my earlier records as follows: The first three were middle aged, of these, the first was married, and gave a history of syphilis, brewer by occupation, erections feeble, white atrophy of retina, unequal pupils — left larger than right, vision obscure in both eyes, cerebro- spinal sclerosis (multiple and lateral). The second gave a history of former syphilis, though at time of observation he was in good flesh and general health excellent, miller and merchant, lives in country; impotent — seldom has erections, but at times has good erections and completes the sexual act. The third is impotent, fails to have erections. The next two are children under twelve years of age; of these, the first is a country boy and has epilepsia mitior, the second, also a country boy, has epilepsia gravior. Another case was that of a civil engineer, sin- gle, aged about 28, with nocturnal epilepsia from excessive masturbation. Additional experience since the discovery of this important diagnostic sign only confirms the conviction uttered in my first paper, viz.: It should receive further consideration at the hands of neurological clinicians, for it appears worthy 87 a place in clinical neurology with Westphal's paradoxical contraction, Erb's reaction of degen- eration, or any of the hitherto recognized diag- nostic reflexes, or clonuses. I have found an analogous reflex to this phe- nomenon in healthy females. It may be elicited in normally vigorous per- sons when that condition of the organ is present that we find coexistant with a desire for coitus, when the sexual act is about to commence, and shortly after coitus, if the sexual desire has not been gratified to satiety. It can be evoked dur- ing priaprism, and during penile relaxation, if power for a second coitus remains in the organ. In conclusion, I think we are on the verge of further most important discovery in the direction of physiological and pathological reflex phenom- ena, and on the verge of an enlarged comprehen- sion of their value in diagnosis and prognosis. I believe that every part of the body supplied by an afierent (sensory) nerve communicating with a center, whether cerebral, spinal or ganglionic, capable of an efferent or motor response, will be found susceptible under appropriate stimuli (elec- trical, mechanical, or special) in normal or path- ological state, responsive in some way, and that this plus or minus responsiveness is yet to have far more remarkable value in clinical estimation than is now accorded it or dreamed of in medic-al minds. For instance, in our clinical investiga- tions, we take into consideration such purely physical reflexes (in addition to the cardiac and 88 visceral movements) as the palpebral, pupillary, naso-pliaryngeal, gastro- cardiac, diaphragmatic, vesical, cremasteric, anal, and the tendon re- flexes of the lower and upper extremities, nor- mal and abnormal, and the clonuses which are of the nature of reflex phenomena prolonged into rhythmical movements. Many of these are more or less influenced by conditions of psychical inhibition like singultus. Then we have in disease often to consider the state of the psycho- physical reflexes, as the in- voluntary sobbing or sighing, unintentional, or causeless weeping, involuntary and unsuppressa- ble laughter, shouting, involuntary exclamations of various kinds, as of fear, disgust, joy, the many, emotional reflexes of hysteria, etc., and sudden involuntary and unrestrainable psycho- motor responses of various kinds, virile erections under erotic psychical impressions. These latter are downward influences, reflex responses from psychical excitation through peripheral impres- sions transmitted through sight or other senses, or originating altogether in ideational center. Then we have the psychical responses to periph- eral impressions, such as the sudden mental states and expressions following physical im- pressions, like the immediate outcry of periphe- ral pain — the true nature of a reflex phenomenon wherever we find it being a peripheral impres- sion transformed into an immediate, or almost immediate, motor response or expression. If we take into consideration how much of our 89 power for regional diagnosis has been aided with- in the past few years by what we already know of these reflexes, especially of the knee jerk, Achilles reflex, the foot clonus, the anal, vesical, cremasteric, and virile, and the numberless and as yet unnamed reflex responses to elec- trical stimulation, how much more may we hot hope for with confidence, if we but persevere in our search for yet unknown manifestations of these phenomena? I have already elicited in certain moribund states, an oral reflex, as here- tofore announced, and a physiological anal re- flex; and have confidence even before its an- nouncement, not knowing it was new, much that Rosolimo asserts concerning the reflex of the an- al sphincters, this latter reflex serving as an es- pecially valuable difitrentiating test where sex- ual failure is to be early distinguished from com- mencing vesical or rectal paralysis. A CASE OF IDIOPATHIC SPINAL HEMORRHAGE. BY THEODORE DILLER, M.D., FELLOW OF THE PITTSBURGH ACADEMY OF MEDICINE. Haemorrhage into the spinal cord of traiimatic origin, while not of very frequent occurrence, has been noted often enough to establish the fact of its occurrence beyond a doubt. But as to whether haemorrhage into or about the cord may take place without an antecedent traumatism some writers are in doubt. However, the major- ity of writers do admit that idiopathic spinal apoplexy may occur, but they are all in accord in stating that the affection occurs only very rarely. In view of these facts I trust the case I am about to relate will prove to be of some value as tending to place the existence of the disease beyond the perad venture of a doubt. Although the case is incomplete insomuch as no post-mortem record is included, yet I believe the clinical history alone will be sufficient to establish the diagnosis. 92 T. K., a laborer aged 51 years, had been in robust health and worked steadily up to the date of present illness He is a tall man of rugged frame; habits of life good; never had syphilis nor any prolonged illness; heart normal. March 12, 1891, after performing his ordinary day's work he went to bed feeling as well as usual. But instead of going to sleep in a few minutes as had been his habit, he remained awake, turning about the bed uneasily until 1 1 o'clock, when he was suddenly seized with an excruciating pain at about the first lumbar verte- bra, which radiated from thence around the abdomen and down the thighs. He at once arose from bed in the intensity of his agony and rapidly walked up and down the room. After a few minutes he sat down upon the edge of the bed and bathed his feet in hot water which his wife had brought for him. While thus engaged, became nauseated and attempted to vomit several times but did not succeed. The gastric distress lasted only a few minutes. While his feet were yet in the water he noticed that they were becom- ing "numb," and told his wife about it. Upon attempting to stand up, soon afterwards, he be- came conscious of a diminution of power in his legs. He became greatly alarmed at this discov- ery and at once got into bed, and became aware, a few moments later, of the entire loss of motion and sensation in both legs. The pain rapidly lessened in intensity so that he was entirely free from it twenty- five minutes after the initial 93 attack. The patient feels sure that his conscious- ness, his memory for words and ability to utter them, was never lost or even impaired during the attack. Members of his family bear him out in this statement. They are further in accord in stating that at no time was the motion or sensa- tion in any of the organs above the umbilicus impaired. The loss of voluntary control of the bladder and bowels was noticed the next day and must have occurred coincidently with the pari- plegia. A critical examination the next day revealed the following conditions: Paralysis of motion complete in both legs ; power in the abdominal muscles greatly impaired ; anaesthesia of all kinds completely lost in both legs, impaired over lower half of abdomen. Patient is unable to expel urine or faeces; was not aware that both bladder and bowels needed emptying. No impairment of mental functions; no pain; motion and sensation in muscles of upper half of body unimpaired. Subsequent history. — Pain never returned, save for an occasional twinge. Urine and faeces taken away regularly by mechanical means. The par- alysis as described continued unchanged until about April 4 (three weeks after initial symptom) when the first signs of the return of muscular ppwer were noted. Patient could at that time move toes of left foot. From this time up to the present date (May i) there has been steady pro- gress towards recovery. He can now move both legs about the bed, flex knees and thighs. Sensa- 94 tion has largely returned. He is not yet able to expel his urine and faeces, although the desire to micturate and defecate now comes to him. Remarks. — The very sudden onset of the symp- toms would preclude the possibility of the trou- ble being due to tumor, aneurism, bone disease or myelitis. An embolus would produce sudden symptoms, but it would be highly improbable that trouble of this kind could cause such a com- plete condition of paraplegia in less than half an hour. So I am forced to conclude that the le- sion was a haemorrhage — and a large one — either in the cord itself or in the structure immediately surrounding it. I am inclined to think the haem- orrhage occurred in the cord itself. As .to the part of the cord involved, the symptoms would indicate the lower part of the dorsal region. THE DIAGNOSIS OF TRAUMATIC I,E- SIONS IN THE CEREBRO SPINAI, AXIS AND THE DETECTION OF MAI^INGERING RE- FERRED TO THIS CENTRE. BY B. A. WATSON, A.M.,M.D., CONSULTING SURGEON TO THE BAYONNE HOSPITAL, SURGEON TO THE JERSEY CITY HOSPITAL, ETC., JERSEY CITY, N, J. The counterfeit can not be detected without an accurate knowledge of the genuine, and in ad- dition to this an exact knowledge of the counter- feit, and likewise a definite knowledge of the difference between the genuine and counterfeit, is still imperatively required. It therefore follows that he who would attempt to detect malingering should always be able to diagnose concussion of the brain and spinal cord. The proper performance of this task requires a full knowledge of the etiology, semeiology and pathology of the morbid condition under consid- eration. Let us, therefore, direct our attention to these essential factors of diagnosis — carefully analyzing each — in order that we may more 96 thoroughly comprehend their relation and bear- ing on each other. It is universally admitted that concussion of the spinal cord most common- ly follows falls upon the feet, buttocks, less fre- quently on the hands when both arms are out- stretched, gun-shot wounds involving portions of the spinal column, a stroke of lightning, heavy blows delivered over the bones of the pel- vis or in the line of the spinal column, etc. The direct effect of these falls and blows is the pro- duction of contusions of the soft parts, etc., which are more or less disorganized by these traumatic agents. The force of these agents is not by any means entirely expended in the production of these contusions, but there will be carried along the bony structure a vibratory motion which will also be imparted in varying degrees to the adja- cent soft parts. A very fair idea may be gained of these vibratory movements by placing the hand on the apex of a bell, suspended in the air, while its base is struck with a metallic hammer; or by the touch of a properly keyed string of a musical instrument when it has been put in motion. The same vibratory motion may be likewise very well illustrated by tapping gently with the finger on a glass jar or other vessel which is partially filled with jelly, and then watching the tremulous movements imparted to the contents by the slight blows delivered on the vessel. The at- tention of the medical profession has been very frequently called to the peculiarities of con- cussive or vibratorj- force by French authors, 97 but its physiological and pathological action has never received that careful study to which it is entitled. A very important factor, which presents itself for our consideration in connec- tion with study of this force is, the fact that it is not transmitted equally well by the various organs and tissues of animal bodies; and, consequently, a direct blow delivered on one part of the body may be entirely negative or result in the production of very little vibratory action, while on another part of the organism the results will be very marked. Thus a blow delivered directly on the nates will give rise to the con- cussive force and be transmitted along the spinal column to the bony walls of the skull, and from this structure to the brain itself, which is in such close contact with these bones. A portion of the . same force will likewise be expended in varying degrees on those organs which are in intimate contact with this line traversed by the traumatic agent. The functional disturbances and the pathological changes in the various organs will depend on the physiological functions, weight, texture, etc., of the parts involved, which need not be enumerated here. A blow delivered on the feet, while the lower extremities are extended^ will be transmitted to the bones of the pelvis^ and then along the spinal column. A somewhat similar result may possibly be produced by a fall on the hands when the arms are extended; how- ever, the force of this blow will be much dimin- ished by reason of the anatomical differences in 98 the parts, particularly the less intimate connec- tion between the bones of the arms and the spinal column, than that which exists between the bones of the lower extremitif s and this im- portant highway for the transmission of concus- sive force. It should likewise be remembered that the more concentrated the direct traumatic force, i. e. , the smaller the area to which it is applied, the greater will be the amount of con- cussive force generated while the other factors remain unchanged. Thus a blow covering an area of four square inches delivered directly over any part of the spinal column will generate far more concussive force than it would if spread over the whole posterior region of the body. In fact, in the former case, if the blow was a severe one, functional derangements and pathological lesions might be rationally expected to follow from the concentrated nature of the concussive force, but in the latter they will be looked for in vain. There is a very marked difference between the concussion in the case of gunshot wounds produced by musket or rifle balls, and that which follows heavy blows or falls — in the former the pathological changes are more circumscribed, while in the latter they may be considered gen- eral. Thus a musket ball having found lodge- ment in the vertebral column, which has in some degree impaired its outer surface without pro- ducing any lesion of the osseous tissues within the canal, the spinal cord will be frequently found in an ecchymotic state at a point approx- 99 imating to the lesion in the spinal column. In connection with this subject, it may be further stated that no single blow, — however great its momentum — delivered on the anterior surface of the thorax or abdomen, could be rationally ex- pected to produce concussion of the spinal cord, since its force would be almost entirely expended on the visceral organs within these cavities. The study of the effects of lightning, and likewise those of electrical currents of both a high and low degree of potency — possess for the surgeon, in connection with the consideration of concussive force, very great interest. The vibratory charac- ter of electrical currents is apparently identical with the other forms of concussive force; and, furthermore, it is readily demonstrable that the physiological action, functional disturbances and pathological changes likewise possess essentially the same characteristics. The fact has long been recognized by the ablest authorities that concussion is physiologically indicated by,a nerv- ous and circulatory excitation or depression. In accordance with this opinion Verneuil has given the following definition of concussion: "A series of phenomena more or less sudden followed by a mechanical disturbance of the anatomical ele- ments, tissues and organs, characterized by a temporary excitation or a depression of the func- tions of the parts disturbed, and likewise pro- ducing anatomical changes which are generally observed in cases of functional activity or re- pose." Mschaaical concussive force, like light- lOO ning strokes and electrical currents, may produce every possible degree of concussion, varying from the slightest functional disturbances, which pass off within a few seconds, to instantaneous death. Further similarity on the effects of these agents is shown by the fact that concussion and even death may be produced by rapidly repeated me- chanical blows or a rapid succession of electrical strokes, while a single impulse would be scarcely sufiBcient to cause even temporary functional disturbance. The pugilist knows that the blows which will promptly render his antagonist un- conscious should be delivered on his head. He therefore seizes the head of his enemy and deliv- ers on it in rapid succession blow after blow until his object is accomplished. Experimentation on animals has shown that concussion of the brain may be caused by slight taps delivered on the head in rapid succession with a hammer, etc. In our consideration of the etiology of concus- sion of the cerebro- spinal axis we have said little in regard to its causation in the brain. It is probably understood, however, that those agen- cies which have already been mentioned are the important factors in its production in this organ as well as the other organs of the body. The same general laws pertaining to the etiology of this morbid condition are as applicable here, as elsewhere; consequently a blow delivered on the head will be more efficacious in the production of concussion of the brain than would be the con- cussive force had it been transmitted to this or- lOI gan from some other part of the body. Further- more, the weight of this organ and other anat- omical peculiarities of the same, must receive due consideration. In this attempt to describe the symptoms of concussion in the cerebro spinal axis, we immediately encounter a difficulty aris- ing from the fact that the functions of the organs are materially difiFerent; and, consequently, the symptoms observed in connection with a trauma- tism in the spinal cord, will produce entirely different symptoms from those found when a similar lesion exists in the brain. The remedy for this difficulty is very simple, and only requires that the symptoms be separately noted as they pertain to lesions in the different organs. A much more serious obstacle is found in the com- bination of all sorts of injuries with those oi pure concussion, especially those having their origin in fractures, dislocations, sprains, rupture and stretching of ligaments, particularly in the spi- nal column, and likewise with the concussion in one organ, the symptoms of which are erron- eously attributed to this morbid condition in an- other. In illustration of the above mentioned error, I desire here to call attention to the fact, that haematuria is frequently mentioned as a symp- tom of concussion of the spine, while I have con ■ clusively shown by my experiments on animals, that it bears no constant relation to lesion of the cord, but on the contrary, following concussive acci- dents, indicates a concussion of the kidney. Fur- thermore, visual changes are frequently attrib- I02 uted to concussion of the spine, while as a matter of fact, the lesions on which these changes de- pend are situated either in the brain or the eye, I am now prepared to assert that the greater part of the organs within the thorax and abdomen are equally as liable to suffer from concussive force as the brain itself; and likewise that con- cussive accidents are much more frequent in these visceral organs than in the spinal cord. This assertion is based on the fact, that these lesions are entirely analagous to those observed in the brain, merely requiring that the proper allowance be made in these organs for difiFerences in weight, texture, etc., factors which must be taken into consideration in connection with the study of the lesions of concussion in the brain and spinal cord. Furthermore, every true con- cussion takes its origin in the same peculiar force. Therefore, if it is desirable to speak of concussion of the brain, spinal cord, etc., why should it not be applied to the lungs, liver, kid- neys, etc.? Would it not be absurd to speak of gunshot wounds of the brain and spinal cord, while the term is withheld from analagous lesions caused by the same peculiar force in other parts of the body? There has recently been made an attempt to employ the term ^''jiervous shock" in- stead of concussion; but this departure' possesses no advantage and has already caused much confu- sion. No attempt is here made to deny that cer- tain portions of the nervous system participate in the concussion; although it is self-evident that I03 the functional disturbance and pathological lesions are primarily developed in connection with the circulatory system. These preliminary comments are made in preference to any attempt at the mere enumeration of symptoms, which, in order to possess real value, must be fully stated and explained. It should likewise be remem- bered that there are different degrees of concus- sions, and these differences are indicated by a corresponding difference in symptoms. It -must now be apparent that the limits of this article compel me to economize space, so far as it can be done without defeating the object for which it was written. Permit me, therefore, once more to call attention to the fact, that concussion always produces either excitation or depression, i. e. , functional activity or repose. The former condition possesses practically little interest, if observed immediately after the application of the concussive force, since it is commonly of short duration, and does not require any attempt at treatment. However, there is another form of excitation occasionally observed in severe cases of concussion of the brain, which commonly makes its appearance from twelve to forty- eight hours after the receipt of the injury." This con- dition is indicated by a full pulse, flushed face, throbbing of the carotids, headache, dry and hot skin, photophobia, noises in the ears, and some- times m arked drowsiness. These symptoms point to the existence of cerebral hypersemia, which is commonly of short duration ; but in some cases I04 it is the prelude to inflammation of the brain. In the severe cases of concussion of the brain or spinal cord, \h& prompt appearance of symptoms indicative of depression, commonly suggests the existence of organic lesion, rather than mere functional disturbances; while, as a general rule, the degree of danger is fairly expressed by the depression. It should, however, be remembered that the symptoms of depression, in order to pos- sess any special value, must pertain especially to the functions which are known to be performed by these organs. Therefore diminished con- sciousness, although the patient may be aroused sufficiently to answer questions, the pupils con- tracted or dilated, relaxation of the sphincters, a feeble and irregular pulse, shallow and sighing respirations, a cold, pale and clammy skin — point very clearly to the brain as the seat of the injury, when the symptoms have followed promptly after the application of concussive force. The symp- toms following those recorded in the above belong to the reactionary period ; the object of this paper does not require that they should be mentioned here. Concussion of the spinal cord is most com- monly indicated by the appearance of paralytic symptoms, which frequently involve the lower extremities — -especially the motor power, and likewise, in many cases, also the sensory. There- fore, in our experiments made on dogs, our at- tention was promptly directed to the movements of these animals immediately after the applica- tion of the concussive force. I05 The following facts possess an important bear- ing on the subject now under our consideration. In a recent summary made from my "Experi- mental Study of Lesions arising from Severe Concussion," I shall here venture to cite the following : ' ' Paraplegia is a very important in- dication of a lesion of the spinal cord, and may have its origin either in a disease or traumatism. This morbid condition may be either complete or incomplete, and when due to disease, it is com- monly slowly progressive ; but if due to a trau- matism, it is rapidly manifested, and soon reach- es its fullest development. In support of this statement, examine the following facts: The whole number of cases in which pathological changes were found in the cerebro-spinal axis were fifty ; the whole number of cases in which any indications of these lesions were observed during the life of these animals were thirty- three, while our record shows that in the last mention- ed class there were twenty- three cases of para- plegia." It will here be observed that there were ten cases in which there had been noted during the lifetime of these animals some indications of a traumatism, but which did not exhibit during that period paraplegic symptoms. It is also wor- thy of notice that in every instance these para- plegic symptoms were observed immediately after the application of the concussive force, and furthermore, that in all cases of complete para- plegia there was not a single case which subse- io6 quently improved. In the large majority of cases of incomplete paraplegia there was commonly some improvement observed during the first three days, but in a few instances the paraplegic symp- toms became more marked during the first twen- ty-four hours; however, even these cases soon showed signs of improvement. It is not claimed that even the immediate appearance of paralytic symptoms after the application of concussive for-ce, in all cases establishes the existence of pa- thological lesions in the spinal cord. I am strongly impressed with the idea that an injury of the peripheral nerves may be followed by tem- porary and commonly local paralysis. A certain degree of importance should be attached to the existence of either anaesthesia or hyperaesthesia in all cases where lesions of the spinal cord are suspected. The existence or absence of pain in these cases — especially true concussion of the spinal cord — possesses very little interest for the diagnostician. In fact, the existence of pain and soreness ought probably to be looked on as having their origin in a contusion, sprain or wrench, involving the vertebral ligaments, mus- cles, etc. , rather than indicating lesions of the cord. Having now presented a few of the char- acteristic symptoms of true concussion of the brain, and likewise of the spinal cord, I desire to add in this connection, that it is certainly' very unfortunate for the science of surgery, that hith- erto it has been the custom of nearly all authors, writing on what they have unfortunately desig- I07 nated as "concussion," to group togetter "half a dozen or more traumatic conditions, difiFering radically from each other in their etiology, semeiol- ogy and pathology. It requires no prophet to assert positively that so long as this grouping is continued there will be a want of clearness in all these articles^that theory will be frequently introduced in the place of scientific facts, that clinical observation will continue to mislead the profession, that good-natured authors, believing that all their predecessors in writing on this sub- ject have told a little truth, will still further add to the existing confusion in their attempts at compounding these incompatible ideas. Let me ask what would be the inevitable result, if med- ical authors should group together under the unfortunate cognomen of "Smith's disease" scarlatina, diphtheria, rubeola, roseola, variola, typhus fever, etc.? However, this combination is no more objectionable than that grouped under the name of " railway spine, " which is so fre- quently employed by many of our surgical au- thors even at the present time. However, the dawn of a new light may be approaching, since Dr. John A. lyidell, in writing on "Injuries of the Back, Including those of the Spinal Column, Spinal Membrane, and the Spinal Cord," states that " the traumatic lesions of the back naturally arrange themselves in three groups, as follows : 1. Injuries of the integuments and muscles, or soft parts generally. 2. Injuries of the vertebral column. io8 3. Injuries of the spinal membranes, spinal cord and spinal nerves.' It must be apparent to any one that this classi- fication presents many important advantages over that which is so commonly employed. An- other serious source of confusion has arisen from the fact, that the term concussion, in former times, was restricted in its application to the brain — although analagous pathological lesions were produced by the same force in nearly all the organs of the body. Furthermore, concussion was badly defined by the old authors; since the term was used to indi- cate a condition induced by a more or less vio- lent shaking of. the brain, whereby serious symp- toms were produced without lesions of the struc- tures. Recent experiments on animals and a careful study of this subject have entirely failed to sup- port their statements in regard to the non-exist- ence of lesions after concussive accidents in the brain and spinal cord. The results of my exper- iments were very conclusive in regard to the ex- istence of these lesions. There were fifty cases in which pathological changes were observed in the cerebro-spinal axis, but only thirty-three of these cases showed any symptoms during life of injury of this centre; it will therefore be readily seen that in seventeen cases, although patholog- ical lesions existed, they were not made apparent I The International Bncyclopsedia of Surgery, Vol. iv, p. 668. Edited by John Ashhurst, Jr., M.D. New York: Wm. Wood & Co. I09 by symptoms whicli could be recognized on the animals. It is likewise important to state in this connection, that there was not a single case ob- served during all of our experiments in which ■we even suspected the existence of concussion of the cerebro spinal axis where we failed to discov- er pathological lesions by our subsequent exam- ination— /(Ji/worfew or microscopual. These pa- thological lesions, in true concussions, are cer- tainly unique in character and nearly or quite pathognomonic in their signification. The only lesions which bear semblance to the pathological changes of concussion, are those arising from contusions, and these are localized, and not dis- tributed generally throughout the organ, which is commonly the case in the former morbid con- dition. However, there is found an exception to these rules in the case of concussion following gunshot wounds, in which the injury is common- ly localized and resembles more or less closely the ecchymotic appearance arising from contu- sions. The functional disturbances and the pa- thological lesions are clearly shown in my exper- iments, to have had their origin in the vaso mo- tor system. In order to illustrate the pathologi- cal changes in the spinal cord which have been observed to follow in a mixed or complicated case of concussion of this organ, I will here cite the report of an autopsy, etc.,'' made on the body of 2 International Kncyclopsedia of Surgery, Vol. iv, p. 790 et seq. Edited by John Ashhurst, Jr., M.D.. New York. Wm. Wood & Co. no a coal- porter who died thirty-four hours after the accident. Autopsy. — There was no external trace of in- jury. The membranes of the cord were healthy. The substance of the cord was contused opposite the fourth and fifth cervical vertebrae. On sec- tion, there was found ecchymosis of the posterior horns of gray matter on the left side, and of the adjacent part of the lateral and posterior columns. There were also limited spots of ecchymoses on the right side, one in the right posterior column, and one in the right anterior horn of gray mat- ter. The gray substance generally was hyper- aemic. On removing the spinal cord and mem- branes, nothing abnormal was discovered in the vertebrae until the posterior ligament had been dissected off, when it was seen that the body of the fourth was separated from that of the fifth, and the left articular process of the fourth had been chipped off. Dr. John A. I^idell, who re- ports this autopsy, comments on it as follows: "The essential features of this instructive case areas follows: i. The cord substance was injur- ed by concussion, and not by any displacement of the parts; 2. the injury was attended by a number of minute extravasations of blood (ecchy- moses) in the gray substance; 3. there were an- aesthesia and loss of motion in both lower ex- tremities and in the left arm; 4. there was paral- ysis of the sphincter ani and sphincter vesicse, which denoted that the reflex motor apparatus was also paralyzed; 5. the anaesthesia passed away in the course of some hours, the return of sensi- bility being noted first in the parts most distant from the injury; 6. hyperaesthesia appeared syn- chronously with the reaction from "shock," and steadily increased in severity; 7. hypersemia of the gray substance was found as well as ecchy- mosis. It should be remarked that the hyper- aesthesia was more severe in the right arm than elsewhere, and this part had not at any time been paralyzed." This case was reported by Dr. Li- dell as a pure or unco>mplicated one of spinal concussion, but I am compelled to question the correctness of the report in this particular, and direct attention to the ruptured ligament, which it seems to me may have permitted a partial dis- location to have taken place — with contusion of the cord — the vertebrae afterwards having been restored to their proper position by the natural resiliency of the parts. The symptoms of paral- ysis were certainly more marked than they are usually in cases of pure, uncomplicated concus- sion of the spinal cord. The following micro- scopical report conveys a very clear idea of the pathological lesions observed in our experiments on animals in the cerebro-spinal axis when there were no complications in this centre.^ "Brain in- tensely hypersemic otherwise normal. Every por.- tion of the cord intensely hyperaemic. There were punctate haemorrhages in the dorsal and cervical regions of the spinal cord, in both the anterior and 3 An Experimental Study of Lesions arising from Severe Con- cussion, p. 22 et seq. by B. A. "Watson, M.D., Philadelphia, Pa. P. Blalciston, Son & Co. 1890. posterior horns, also in the middle commissure." The striking analogy existing between the path- ological lesions in cases of death caused by elec- tricity and the other cases of concussion, may be probably better illustrated by giving a condensa- tion of the report of the autopsy made by Dr. Carlos F. McDonald on the body of William Kemmler, after execution by electricity, since this examination has been more carefully detail- ed than any of the others. The others, however, entirely agree with McDonald's so far as given. McDonald's report is as follows: "Rigor mortis marked. On incising the skin over the sternum, the blood which escaped was unusually dark and fluid, remained so on exposure. Lungs: tardieu spots were noticed on the posterior border of the lower lobe of the left lung, so also in the middle lobe of the right lung. Heart: valves and sub- stance normal, ventricles empty. Liver: blood from cut surface of dark crimson hue. Gall bladder: distended with bile. Spleen: normal. Kidneys: both markedly congested. Brain: capillary hemorrhages were noted in the floor of the fourth ventricle, also in the third ventricle and the anterior portion of the lateral ventricle. The perivascular spaces seemed to be distended with serum and blood." Dr. Spizka's report of the preliminary microscopical examination is as follows: "The brain, spinal cord and peripheral nerves appeared strictly healthy in every part ex- amined, except in the area corresponding to the discolored (anaemic through the contraction of "3 the vascular channels) area of the Rolandic and pre-Rolandic regions, the ventricular surfaces, the pons and the medulla oblongata. The latter, which had been the seat of post-mortem preser- vation of temperature approaching that of the normal human body, were distinctly softer than the observer has ever been accustomed to find these parts in autopsies on persons of Kemmler's age and performed so soon after death. The hsemorrhagic spots in the fourth ventricle, which were strongly marked, were not accompanied by signs of parenchymatous rupture of large blood vessels. Hence they may be regarded as having the same significance as the "taches de tardieu" found on the surfaces of the organs, notably the heart and lungs. The peculiar softened vesicu- lar zone of tissue underlying the outermost lay- er of the cerebral cortex is noteworthy, as "the destruction line" runs parallel to the free surface of the brain and does not dip with the sulci. Ex- amination of the fresh specimen revealed the ex- istence of vacuoles (probably gas bubbles) in the ganglion cells and in the parenchyma of the "de- struction line." From the fact that no haemor- rhages had occurred in this softened area it is a just inference that it was produced after life had become entirely extinct, for the continuance of a blood circulation in a softened brain area is in- compatible with the bloodless appearance, al- ready noted, and the absence of capillary haem- orrhages in this very district while they were 114 present in those remote from the site of the elec- trode." In order to approach the consideration of ma- lingering, it is necessary to devote some attention to the traumatic conditions which frequently com- plicate concussion in the cerebro-spinal axis, since the majority of authors still include these morbid conditions under the head of ' 'spinal concussion, ' ' ' ' railway spine, ' ' etc. Fractures and disloca- tions of the vertebrae require little attention, at the present time, since they are easily diagnosed. The only exception to this rule will be found in those cases where there is a complete absence of deformity, which may be the case where the frac- ture consists in chipping off a portion of the ar- ticular vertebral surface, etc. , or in an incomplete dislocation of a vertebra, in which the natural resiliency of the ligaments and muscles has re- stored the symmetry of the parts. In these cases, it is thought that the careful and observing sur- geon will not be compelled to remain long in doubt as to whether the patient before him is a malingerer, or suffering from a real traumatic in- jury ; since the prompt appearance of objective symptoms will certainly be largely dependent on the locality of the injury, while their degree of severity will depend very much upon the extent and character of the traumatism. There now re- mains for our consideration in connection with this subject, contusions, sprains, twists and wrenches of the back, which are entitled to a more thorough analysis than can be given 115 them in this article, on account of their medico- legal bearings, in litigated cases. The study of these morbid conditions, it should be remem- bered, will be greatly simplified by bearing in mind the fact that their symptoms, the primary and secondary effects, are entirely analogous to injuries of the same character in other parts of the body. It is claimed that the spinal col- umn and the bones which connect directly with it, are provided with ninety-nine articula- tions. The symptoms which characterize the morbid conditions now under consideration are pain, swelling, tenderness under pressure and occasional ecchymoses. The existence of the symptoms will be limited to the area involved in the traumatism, while the degree of severity will depend on the intensity of the injuries. There may be likewise, in some cases, constitutional disturbances which will aid in establishing the existence of a morbid condition. The ecchy- moses and swelling are objective symptoms, and consequently entitled to due consideration, while the pain, stiffness and tenderness under pressure may require confirmation. The verification of the patient's statements on these points, and frequently on others — especially questions in- volving the existence of paralysis — might be defi- nitely put at rest by the proper use of an anaes- thetic, which ought to be frequently employed in medico-legal cases. The general surgeon no. longer hesitates to employ this agent in his pri- vate and public practice for diagnostic purposes, ii6 and why should it not be thus employed for the purpose of securing justice in our courts? Drunkenness and syncope may make the diag- nosis more difficult in certain cases of concussive accidents, whether it be pure or complicated con- cussion ; but these factors are of short duration, and therefore cannot continue long to embarrass the surgeon. Having presented our views on the chief factors involved in the diagnosis of the so- called "railway spine," therefore we are prepared to devote a few minutes to the malingerer. It is unfortunately too frequently the case that a sur- geon commences his examination, in medico- legal contests, after having fully formed an opinion, or at least a bias or prejudice. This, in many cases — in fact, almost universally — arises from the want of an analytical mind, and likewise the want of any carefully arranged system of exam- ination. These are very serious defects in the expert witness and, when fully demonstrated, should disqualify him to give testimony. There is another serious defect, frequently observed in the members of our profession, which sometimes has its origin in laziness, although occasionally in an inordinate greed — where the physician has been accustomed all his life to give an opinion to a patient without either an examination or thought. It will be perceived that I have not yet reached the case of the malingerer ; but I have thus far merely paid my respects to those Nwho aid and assist the malingerer. The malin- igerer is certainly entitled to a careful and thor- 117 ough examination, and each surgeon employed in the case ought to proceed in his examination with the same degree of care and caution that the most conscientious chemist would exercise, when required to make a chemical analysis in the interest of justice. It therefore becomes highly important to learn the true history of the litigant, and likewise that of his father, mother, brothers and sisters. All these matters have a special bearing on the case. It will be readily admitted that any person who has established a good character for truthfulness and honesty ought not to be classed with a mere adventurer. In the examination of all the factors involved in these cases of so-called "railway spines," the fact should never be lost sight of that correct sci- entific opinions can only be reached by a systematic, methodical and painstakijig investigation. Let us here present a brief risume of some of the points which have been more or less consid- ered in this paper. 1. The term concussion, as used by those who first employed it, was erroneously defined, and unfortunately restricted in its application to the brain. These errors had their origin in a defi- cient knowledge of the pathological lesions en- gendered by concussive force. 2. Concussion is a more or less violent shaking or agitation of various organs in the body, pro- ducing functional derangements dependent on vaso motor changes and well-defined pathologi- cal lesions. ii8 3. Concussion may be either general or special, general when several organs are involved at the same time, or special when the entire concussive force is expended on a single organ. 4. The symptoms arising from concussion will chiefly depend on the extent of the pathological lesions and the functions of the organs. 5. The frequency with which concussion will occur in any particular organ will depend on the point to which the concussive force is applied, the relative weight of the organ, the character of its texture, and the protection afforded by its anatomical surroundings. 6. The fifth statement supplies the explanation of the comparatively frequent occurrence of con- cussion of the brain, lungs, liver and kidneys to that of the spinal cord. 7. Concussion of the brain and spinal cord iS' always attended with immediate symptoms. 8. Concussion of the brain or spinal cord with- out immediate symptoms is a mere hypothesis — a myth — and has no real existence. 9. There is no pathognomonic symptom of concussion in any organ of the body ; but a thor- ough, systematic, methodical examination by a skilled surgeon will secure a correct diagnosis. Finally, I desire to reiterate the fifth conclusion expressed by Dr. Henry Hollingsworth Smith, in a paper which he read before the Surgical Section of the American Medical Association in 1889, which is as follows : ' ' No physician should go into court and swear that a plaintiff has had a concussion of the spinal cord, or of its nerves, unless he has proved the disturbance of the nor- mal functions of the cord, as shown in sensation or motion, or both, and that the symptoms ap- peared soon after the injury," A CONSIDERATION OF TRAUMATIC LE- SIONS OF THE SPINE RESULTING FROM RAILROAD AND OTHER INJURIES— THEIR ETIOL- OGY, PATHOLOGY AND DIAGNOSIS. BY THOMAS H. MANI/EY, A.M. M.D., VISITING SURGEON TO HARLEM HOSPITAL, NEW TORK. Since the enormous extension of the railroad system — surface, submarine and elevated — where- in steam is utilized as a motor, the attention of surgeons and the profession has been attracted to certain special features, which commonly at- tend or subsequently follow accidents, sustained by individuals on cars in motion, on iron rails. Many have maintained that injuries resulting from railway disasters, possess characteristic and positive lesions, which are peculiar to themselves, in symptomatology, pathology and termination. While, on the contrary, there are not a few, who take an opposite view and claim identity of an- alogy, between them and other disorganizations of tissue, in which the collision of heavy, mov- ing bodies has been the direct cause, or in which I20 similar physical agencies, but devoid of steam propulsion, have come into action. In the meantime, as if to give stability and warrant to the former allegation, certain practi- tioners in different sections of the country have organized, and now the profession is threatened with another specialty; we have the Society of Railway Surgeons. We have in several of our large cities and railroad centers, hospitals owned and controlled by railway corporations, or the medical officers in the immediate employ of roads. These are maintained by the companies for the purpose of treating those of their em- ployes injured while in their service. With those hospitals owned and controlled by individual surgeons or colleges, services are usually render- ed by contract with the railroad corporations, much to their advantage; for while professional aid is procured at a minimum rate, the compa- nies are also protected, in having their maimed or injured under such supervision, as will effectual- ly guard against malingering; and, besides, should a civil suit arise, the surgeon is drafted into their service. So far we have no special section at the meet- ings of the American Medical Association, for railway surgeons. Is it necessary to further sub- divide the field of surgery? While all general surgeons are presumed to possess ample qualifi- cations to serve their country in the field, in times of war, yet France, Germany and Eng- land have each, supplementary medical institu- tions to equip medical graduates for military duty. With our rapidly extending lines of railroads, which radiate and ramify in every direction, on which more than one hundred thousand men are employed and millions of travelers ride, we can easily apprehend that the number injured annu- ally must be very large. Do their injuries or lesions differ in their dynamic essentials, their anatomical characters or pathological phenomena, from those sustained by other causes in civil life? Do those injuries occasioned by collisions on railroads or otherwise in connection with travel or employment on them, constitute a certain and separate category of features, which are charac- teristic and peculiar, with regard to their local destruction and ultimate termination, and de- mand for their successful treatment the superin- tendence of one of special skill and extended ex- perience? I think the majority will answer in the negative. ETIOLOGY OF SPINAI, INJURIES ARISING FROM RAILWAY ACCIDENT AND OTHER CAUSES. Conditions of the spine arising from trauma in a general way, may be resolved into two divisions, viz., those in which there are' distinct and defi- nite lesions, and those in which there are func- tional disturbances, without any visible alteration of structure. With the former chiefly are we con- cerned, on the present occasion. It has been seen that many regard railroad in- juries of every description as possessing charac- teristic features. Everyone, who has had any 122 hospital service, into which are entered casualty cases from railroads, has noticed that the destruc- tion of the soft parts is very much more than is seen from other injuries, so that when amputa- tion becomes necessary, and we trim sparingly, in a few days after, the flaps are gangrenous and we must go further up; or if we secure primary union not infrequently we will see an insidious osteo-myelitis arising; requiring a later and more extensive section of bone. It is this class of cases, too, in which we all must often notice that fearful phenomenon, of which so much is seen and dreaded by military surgeons — secondary shock. It is important, therefore, before we can make a rational study of this question, that we ask ourselves, what a serious railway accident really is, which should give it those fearful attributes of destruction, or why they should be more com- mon now, than formerly. In considering the physics of the study, we must have a correct notion of inertia, momen- tum, velocity, power, resistance, motion and di- rection. A body at rest, is struck by a flying missile, the penetrating power of which is in di- rect proportion to its initial velocity. In study- ing railway injuries, or rather those occasioned by collisions on railways, we will discover the same identical laws in effect, as in the case of a flying missile, but the picture is reversed; the human being is then in a passive, inert state, 123 wholly beyond his own control at the moment of collision. In the practical flight of an express train down an inclined plane, that ponderous mass of metal, the engine, and the passenger coaches are literal- ly shot through space. In this state of motion, in making a sharp curve, or otherwise, the wheels leaving the rails, this train and its human freight, are sent onward, until the initial motion impart- ed by the locomotive and by increased gravity, has spent itself on the parts, in a state of inertia at the instant of collision. What gives to rail- way rolling stock its great destructive properties are its weight and speed. The car trucks to sup- port their burdens, with safety, must be heavily constructed; besides, the more weighty their wheels, the more regular and easy their motion. To supply the demands of travel for fast mail and freight transportation the moving rate of speed has been very greatly augmented, hence danger, in the event of an accident, is proportionally in- creased. We have then, in the modern moving train, pro- pelled by steam, two factors indispensable for force, viz., weight and speed, which are always brought to bear on the body, in cases of sudden and violent concussions, when it in whole or part, is crush- ed, stretched or twisted. In many respects there is no little analogy between the spine and a train of cars. We may suppose each vertebra a car; the interlying cartilage a buffer; the ligaments connecting links and the head, the massive ma- 124 chine. In the center of all the medulla cerebralis et spinalis, the precious freight, the passengers. Of all the traumatic lesions which have defi- nite and presumptive pathological lesions, aris- ing in consequence of railway accident, or other mishaps, there are none, which have given rise to so much investigation, study, experimenta- tion and vehement controversy, as those arising from railway accident, and which occupy the cerebro- spinal axis. Eric Erichsen was among the first who contrib- uted anything in a methodical way on the subject of spinal lesions attributable to railway casualties. In America Dr. B. A. Watson, of New Jersey, conducted a very extended series of experiments on the lower animal (the dog) with a view of further clearing up mooted pathological ques- tions and endeavoring to connect symptoms with pathological changes. Since the appearance of Erichsen's lectures we have had such a pathological entity as the ' 'rail- road spine." For he taught that the clinical features, morbid anatomy and history of certain forms of spinal injury, caused by railway acci- dent, were unique, definite and characteristic' Watson, on the other hand, after his painstaking, laborious and exhaustive investigation, conclud- ed, to quote his own language, that "concussive accidents never produce pathological changes in the spinal cord, except when g^eat force has been I Watson, An Kxperimental Study of Traumatic LesiGn of the Spine 125 applied to the spinal column, and these cases generally, if not always, are complicated with a fracture, rupture and stretching of the ligaments, or severe lesions in other parts of the body, which terminate quickly in death." Erichsen ventured to aflSrm that neuroses of every phase and degree, from profound melan- cholia, dementia or paralysis, might arise, either immediately after the railway collision, or at a remote date. His observations are mainly limit- ed to the elements of the cord and brain with the meninges, and he takes but little notice of the part which the enveloping tissue play, either in association or as independent factors. The mus- cles, tendons, ligaments, extravascular supply and peripheral nerves are wholly ignored, and he looks solely for pathological changes to support his theory in the medulla and meninges. Wat- son's experiments having been conducted on the dog dropped through a chute, we must com- pare the striking difference between them and man, with respect to their physical conformation and mental attitude, before we can properly esti- mate the clinical application of these experi- ments. In one the spine is nearly perpendicular, and we must not overlook the element of fear. In the otber, the spine is horizontal and has four supports instead of two, besides psychological influence is wanting. Man's head is very heavy in proportion to his size. The quality and di- rection of concussive force possessing but little analogy with such as is inflicted in railway acci- 126 dents, we cannot unqualifiedly apply those ex- periments in the lesions under consi'deration. Although the views of both distinguished authorities here cited are widely divergent and antagonistic in many respects, though, strange as it may appear, in one direction, at least, they evidently agree, for neither appears to attach much, if any, importance to the direful conse- quences to the integrity of the spine, which may follow injury of the soft parts independent of implication of the cord itself. Neither author has been able to supply anything but very scant pathological data from post-mortem examination on the human body, where death has been di- rectly or indirectly caused by spinal injury. In this connection an effort will be made to demonstrate by anatomical analysis and patho- logical observation that, quite independent of alleged morbid states which are manifested by clinical symptoms, we may and frequently do find the motor functions of the spine temporarily im- paired orjlost by lesions which in no way direct- ly implicate^the cord itself. To proceed intelligently with the separative causative factors, we must have a clear compre- hension of the varied structures which we have to deal with, their relations and functions. Among^the laity, and even medical circles, some- times a most confused notion would seem to pre- vail with regard to injuries in the rachidian re- gion. What is the spine? We will be told that so and 127 so met with an accident and has seriously injured his "spine." Lay people have a vague but sin- gularly correct impression, nevertheless, that when paralysis immediately follows injury, the "back is broken." With our profession, the general opinion of a serious injury of the spine always implies that the cord has participated in the lesion. Neither view is correct, for we may have complete paraplegia without a broken back, and vice versa. And we may too see individuals invalided for life when the great nerve cylinder and bony arches have entirely escaped. The spinal column in man is maintained in the upright position by a powerful set of muscles, with an accessory set of stays, the numerous lig- aments which, though permitting varied move- ments, firmly retain the vertebrae in position. Besides those osseous spurs given off by each vertebrae, serve as levers and are so intimately interlocked that even in the dead body they are detached from each other with diflSculty. If the vertebral column be denuded of its mus- cles and traction force is applied in opposite di- rections, the arches or transverse processes will give way often before the ligaments. As the dorsal vertebrae are firmly braced on either side by the ribs, the spine, in the event of a trauma- tism, will yield less in this situation, but as the lumbar region is reached lateral support is want- ing, and on this the whole weight of the head and trunk is borne. Speaking in a general way, we may say that 128 among the manifold and varied purposes which the rachidian column serves, the most obvious and important are: i. To form the posterior boundaries of four cavities, if we include the sacrum. 2. To support the head. 3. To carry all viscera and structures lying beneath the un- der surface of the cranium. 4. To provide lodge- ment and protection to the spinal cord. Its weakest and most superficial segment is its most mobile; its middle the most fixed, and yet — to employ a paradox — is in constant motion, through costal action on either side. The lum- bar region is the most powerful and is the center of flexion between the trunk and pelvis. It may be well in this connection, while cou- sidering the powerful and complicated structure of the spine, to remember that that organ within the tubular canal, the cords, is but fifteen inches long and weighs but an ounce and a half; that it floats in a water bed that protects it from pres- sure and ordinary jars. The cervical or lumbar segments, in the event of great and concentrated violence, permits of a distinct, lateral swayingmo- tion, so that the momentum of force may be spent rather on the ligamentous, osseous or muscular - parts, than be transmitted to the cord or brain. Besides either extremities of the spinal column where force may be applied, either in the way of traction or compression, it may be also brought to bear from behind, or latterally. Violence, to reach the cord interiorly, must first encounter the viscera, or disorganize the spinous bodies, 129 which would be impossible without immediate destruction to life. Of the different regions, probably none can sus- tain a crush or fall with as much impunity as the dorsal. The osseous structures of the spine, here lie below the posterior costal curves and force is diffused through the elastic contents of the thor- ax, or one or more ribs are fractured. The same degree of violence inflicted on the cervical re- gion, suddenly and unexpectedly, would have mortal consequences. But, when one has even a second's notice, he instinctively shortens his neck, obliterates it, as it were, by crowding it into the thorax, by raising his shoulders up to the ears, depressing the chin to the sternum and the occiput to the vertebree prominens. Accordingly we find the lumbar region the most vulnerable; for we may regard this segment as the centre of a hinge joint, and, as might be expected, is oftenest found the part which suffers in these spinal injuries, from which a patient may, for a time, survive. But the lumbar seg- ment has a powerful and compact development ; hence, simple violence, to compromise its deli- cate contents, must be direct and great, so that, as Watson discovered in his unique experiments on the dog, the lesion of the cord often, in itself, is of but minor importance, in comparison to the rupture or laceration of an organ vital to life. It would be rational to assume that, in the vast majority of cases in which force operated in the cervical or dorsal regions with sufiBcient concus- I30 sion to fracture bone, death would seem an al- most inevitable consequence. In eight cases which have come under my observation, in which the brunt was borne by the lumbar spine, six died, one in six hours, two in a week, and one lived three weeks. One recovered completely, and the other left the hospital, paraplegic. There was paralysis in all these cases in the beginning. Three of them were the result of railroad acci- dent. In all the cases, the kidney sustained as- sociate lesions. As far as the etiology of traumatic spinal mal- adies goes, my experience is mainly in harmony with the views promulgated by Dr. B. A. Wat- son, of New Jersey, in his experimental Work on the spine, viz. : that in traumatisms of the spine, attended with paralysis, we will always find path- ological lesions involving it, of a definite and positive description. Prof. Erichsen, in his lecture on spinal concus- sion, details at considerable length a large num- ber of cases, in which symptoms of paralysis at varying intervals after railroad accidents appear- ed. In some of these cases, there were compli- cations of brain symptoms, with affections of the nerves of special sense. In many there were dis- orders of vision or hearing, melancholia, halluci- nations, neuralgias, loss of memory, unsteady j^ait in walking, numbness and hyperaesthesia, and other ailments aflecting the nutrition of the body. In none of those cases were pathological 131 changes present which could be proven, but it was assumed that ansemia of the cord existed, or that there were either chronic meningitis or myelitis. Having seen myself a considerable number of cases of injury to the back, arising from railroad injuries, in none have I ever encountered these sequelae. And, with proper deference to the dis- tinguished author, yet I am convinced that his premises are unsound and untenable. And I am satisfied that his conclusions, though ingeniously constructed, will not meet with favor among those of extensive experience in the treatment of rail- road injuries, or serious traumatisms of the spine. There are, however, other serious lesions which may attend injury of the spine, which have been described by no writer in modern times, except Olliver.^ I refer to those which are limited to the peripheral nerves, muscles, tendons, liga- ments, vessels or bone ; which are attributable to strain, twist, pressure, laceration or contusion, and give rise to extravasation of blood, to in- flammatory exudates, synovitis, periostitis, ab- scess, amyotrophic changes, myopathies, throm- bosis, embolism, phlebitis, cellulitis or anchylosis, and which may and often do, in early childhood, or even in middle life, be the starting-point of various organic maladies. Extrinsic spinal injuries are very common. The vascular system supplying and maintaining the nutrition of the cord ; its coverings, the meninges; the rachidean structures, osseous, lig- * Traits Maladies de I'Epine, ed. i, p. 207. 132 amentous and muscular, is peculiar in its arrange- ment, although in many respects it is similar to the cranio cephalic, in that there is a free inter-, communication between the peripheral and the deep vessels. Hence, the explanation how in- flammatory conditions are propagated from the superincumbent cellular tissues to the synovial investment of the vertebral joints, or to the ele- ments of the cord, when the process is in relation to the cervical region. I have on three occasions met with cases of spinal meningitis, in which the primary injury was first borne on the nates, or over the shoulders. A case of this description I saw with Dr. W. B. Fisher two years ago, in the town of Yonkers, N. Y. The patient was a young lady who, while on roller skates, fell on her left nates and side. She was very sore, over the seat of injury, for two or three days, the parts being swollen and tender. Soothing applications were applied, and she was confined to bed. As the fulness and pain commenced to subside over the gluteal region, she began to complain of "pins and needles" (formication) in the soles of her feet. This was followed by numbness, and on the seventh day after injury she was com- pletely paraplegic. On the tenth day she died, of typical meningitis of the spinal cord. My two other cases were seen in hospitals. In one, spinal meningitis developed six days after the patient was violently clubbed by a police offi- cer. On the second day after his castigation, his 133 mid-dorsal region was one mass of welts and bruises. The skin over the injured area was mot- tled, hard and lumpy. With him, paralysis was confined to the lower extremities, but there was much more convulsive spasm of the ■•xtremities than in the preceding. His case was remarkable with respect to its termination, as he recovered from the meningitis, so that he was able to leave -the Workhouse Hospital, on crutches, i/iree months after injury,, the paralysis not having wholly disap- peared. No doubt a thickening sclerosed condi- tion of the neurilemma of the nerve roots lingered, which might account for the nerve symptoms. In my third case, the patient was injured by being knocked down by a passing team. Two ribs were fractured, but she was able to get on her feet, and walk home without assistance. She was brought to the hospital on the fourth day, with symptoms of incipient spinal menin- gitis. The disease made rapid progress, quickly extending into the cervical section. She died on the fourth day after admission into hospital. On post-mortem examination we found, on the left side, the sixth and seventh ribs fractured, close to the transverse processes. A large, "dif- fuse extravasate of blood was discovered under the long, broad bands of the serratus magnus muscle, and the connective tissue on the right side. In places, it was liquid, in others partly organized, but for a very considerable radius about, the tissues were deeply red- stained by the escaping hsematin. 134 The tendinous and ligamentous structures in the vicinity of the sixth and seventh cervical vertebrae were softened and thickened. On en- tering the spinal canal, no haemorrhage was met with. The dura mater was greatly distended with a turbid, flocculent serum. Between the arachnoid and pia mater, throughout the cervical area, as far as the atlas, a fibro-plastic exudate was seen, which insinuated itself along the hori- zontal septa into the lateral sulci of columns. The medullary substance of the cor^ was softened in the centre, and was everywhere dotted with mi- nute ecchymoses. Besides those lesions which involve the cord secondarily, and have reference to propagation of irritation or infection, through the nerves, vascular channels or lymphatics, we have anoth- er important group arising from muscle or liga- ment strain, from contusion of the peripheral nerves, which regulate movement and nutrition of all the overlying structures, from the integu- ments inwards, from haemorrhage, cellulitis, peri- ostitis, synovitis, arthritis, fatty degeneration of muscle, limitation of muscular action or anchy- losis. The etiological factors in all the above were primarily concussive force, and conditions dependent on vital phenomena. Sprains are commonly understood as trivial wrenches or twists of an articulation, attended with pain, swelling, and ecchymosis of the in- teguments. Authors give them little noticed But over strain or violent sprain of a joint, or . 135 series of joints, attended with extravasation of blood into the articulation, with laceration of muscle or ligament, may be the starting-point of very grave organic changes, particularly in the young, or those inheriting a feeble constitution. In spinal injuries, chronic, multiple synovitis, periostitis, softening, wasting and atrophy of the muscles, with weakening, stretching or displace- ment of the ligaments, are a few of the sequelae, in aggravated cases. I have met with a case, in which a violent twist at the ankle-joint origi- nated a diffusive osteo-myelitis which ultimately necessitated amputation above the joint. We may have, in one or more joints of the spinal column, the same precise pathological con- ditions as obtain in the extremity ; but as the spinal articulations are all deeply lodged, they more often escape. And, if they should be the seat of sprain, it must, during life, be rather in- ferred than proven. Nevertheless, when a person comesunder our ob- servation, who is injured in the back, who has a febrile pulse and a high temperature, with a local fulness and hardness over a localized area of the spine, but in whom sensation and motion are perfect, there can be no doubt as to superficial or extrinsic nature of the lesions. The most frequent source of injury to the lig- amentous and muscular structures, is by indirect force at either terminus of the column. The dorsal and lumbar regions suffer most from this form of violence. One falls from a considerable 136 height, or is hurled a short distance, striking on his nates or hip. The spine is bent backwards, forwards, or laterally, the inertia of the head, shoulders and trunk is mostly spent on the lum- bar vertebrae. Not infrequently, however, serious strains are induced by concussive force coming from an op- posite direction ; as when one is precipitated in such a direction that the point of impact is on the shoulder and side of the head, when the whole weight of the lower trunk and extremities im- pinges, with great momentum, on the upper mo- bile, lumbar segment. These accidents, involv- ing only the extrinsic structures of the spine, then, well deserve a careful study, for it cannot be denied that, when of a severe nature, the original pristine strength of the spine is forever lost, and locomotion will be always thereafter diflBcult and painful. If they occur in a maiden, she can never properly fulfil the duties of matri- mony with safety ; nor, in fact, perform any sort of labor requiripg considerable effort. A consideration of those infirmities of the spine, exclusive of the neuroses of the cord, fol- lowing spinal injuries, opens the way for a new line of study, which may be cultivated with great interest to the surgeon and practitioner, and ad- vantage to the crippled. I have met with a few cases of spinal injuries in adults in which there followed absolute and permanent impairment of power, while the cord remained free. 137 The first case I saw with Dr. Sheahan, of this city, in which the patient, a young woman, was suffering from the effects of a fall into a deep trench on a dark night. She thought she struck on her shoulder but was not positive. She was confined to bed for more than six months and was unable to sit in the upright position for more than a year. The lumbo-dorsal muscles were markedly atrophied on both sides and the spinous processes of the lumbar vertebrae pro- jected out so that the tips could be easily counted. There was no neurotic condition of any descrip- tion. Her infirmity was local and was confined to the muscular and ligamentous structures alone. She was, when I saw her, wearing a very heavy gypsum jacket. Without it she was al- most powerless to move. Her general condition was good, with a fair muscular development. There had never been any question in this case, or the two others which will be recorded, as to suits for damages. It is now two years since I saw her, and her physician writes me that though she makes a living with the needle, yet she is as weak and helpless in the back as ever. The second case was also in a woman. She was nineteen years old, and was injured while descending the steps from an elevated railroad station. She was near the surface when she slipped and fell with great violence on her back. Being unable to stand or walk, she was conveyed home in an ambulance, where she lay in bed four months. She was now examined by the railroad 138 surgeon, who was inclined to regard her troubles as trivial, inasmuch as there was no central im- plication of the cord. At this time she was ad- mitted in the hospital. On examination in the lower lumbar region it was evident that an ab • scess was forming close to the inner border of the quadratus lumborem muscle. On freely incising it a fistulous tract was discovered ex- tending down to the transverse processes of the second and fourth lumbar vertebras. By enlarg- ing the wound, we came down on those proces.ses of bone which were necrosed, and with the ron- geuer cut them away. There was a considerable area of diseased tissues along the line of the in- cision, which was scooped away. The incision healed by granulation, beginning at the bottom, but it was more than three months before it closed in entirely. She now occupies a position in a dry goods store, but there remains a rigidity of the muscles of the back, which greatly limits the normal stooping movement and prevents her from occupying her former position. My third case of permanent impairment of func- tion following severe injury of the back, was a carpenter, who while in a stooping position was struck over the lumbar region by a falling piece of timber. I saw him shortly after he was in- jured. There was no palsy, but his spine was rigidly fixed and over the seat of injury there was great pain. He passed blood in his urine, both as coagula and in the fluid state, in such quantities as to threaten fatal anaemia. By the 139 aid of refrigerant drinks and cold applications on the nephritic regions it gradually lessened and in a few days completely ceased. This man had a slow and painful convalescence. For many months he could not maintain the trunk on the femora in sitting or walking, without making a lumbar support, and for three years he was an invalid. For a long time there was a marked and considerable fullness over the left kidney, whether attributable to haemorrhage be- neath the capsule into the parenchyma or steno- sis of the ureter with hydronephrosis, we are unable to say. It, however, gradually diminished in size and ultimately disappeared. These three cases constitute all the lesions of an extrinsic character clearly attributable to over- strain or contusion of the spine, in which perma- nent disability in varying degrees have followed injury, that I have seen. In the treatises and brochures of Abercrombie, Guthrie, Brodie, Cooper, Ollivier, Chappioneare, Duplay and Richet many cases of this character are mentioned but not fully described. In analyzing the phenomena of those painful neuroses over the long axis of the rachidian plane, we cannot forego at least a cursory exam- ination of the nerve supply, of the meninges, the bony framework of support, the soft parts and integuments. The dura-mater is supplied mainly b}' extreme- ly delicate prolongations inward of the sympa- thetic through the intervertebral foramina, and 140 by ganglionic fibres from the nerve roots which pierce the neuralemma, and are reflected inward and upward in opposite directions. The deep osseous tissues, ligaments and cellu- lar elements in the dorsal region, are provided by the posterior ramifications of primary divi- sion of the twelve dorsal nerves. The anterior branches of the six lower dorsal nerves supply the three sets .of muscles which laterally wall in the abdomen. The arrangement of the lumbar nerves is simi- lar to the dorsal, but it may be noted, in all the regions of the vertebrae, that, beginning in the superior segment, the cervical nerves send pro- longations into the thoracic region and freely inoculate or are blended with its nerve-trunk, the dorsal with the abdominal, and the lumbar with the pelvic or sacral nerves. As a result of violence to the spine we may have haemorrhage, laceration of substance, in- flammation, peripheral paralysis or neuritis. The consequences arising from these various condi- tions are important or serious in proportion to their extent, the age of the patient, sex, and the condition of health. One of those pathological conditions may be dependent on the other. For instance, sanguineous extravasation into or-along the muscle sheaths, if properly treated and of moderate extent, will rapidly disappear. But under varying circumstances it may give rise to irritation, inflammation or suppuration. I^ocal 141 inflammation may he confined and its spread prevented. As a rule, however, unless very great injury has been inflicted, the processes of repair in the spinal coverings are rapid and complete. This may be explained partly, perhaps, by their greater vascularity and elasticity. There are, nevertheless, occasions when a muscle is subjected to sudden and considerable strain; the result may be very serious. Such we sometimes meet with, in those cases of irreduci- ble luxations at the shoulder joint, in which the muscle has lost its elasticity with contractility, and we fail to retain the head of the humerus in position after replacement. Dire results may follow rupture of the meningo-rachidian veins. Their walls are very thin, hence, when ruptured, fail to close in the rent. Bleeding from these vessels is a most prolific source of secondary in- flammation, of the meninges and pyelitis, by pyogenic processes, propagated either through the lymph channels or the blood vessels, which, in this situation, communicate very intimately. Primary and direct disorganization of the os- seous structures of the spine, without mortal implication of the medulla-spin alls, or such a lesion as will at once and permanently destroy the conducting power of the spine below the area of contact, is very rare. Pathological changes involving the bones of the spine, after injury, are mostly secondary, and are not often seen, except in early life. Even 142 then, when met with, after an alleged injury, it might become an important question to decide just what part the traumatism exercised as an etiological factor in the initial changes, or wheth- er or not the necrosis or caries was rather attrib- utable to influences originating within the or- ganism itself, the development of which, imme- diately following the accident, being rather an adventitious circumstance. The same observation might apply to synovial implication of the manifold articulations of the spine. In all grave spinal traumatisms, provided the patient survive immediate shock, spinal- meningi- tis arises, and, in time, the brain shares in the changes which commenced in the cord. Hence, when the basilar membranes are reached, and those of the meduUa-oblongata, the respiratory centers become the theater of inhibitory action, and life is quickly terminated. The subarachnoid cavities of the brain and spinal cord freely communicate. In serious in- juries of the cord we often have premonitions of approaching dissolution, accentuated through the nerves coming from the cord, within the skull, while all the mental faculties are yet un- dimmed, and the patient himself is warned of the terrible change which awaits him only by indi- cations made manifest through those nerves which preside over respiration and phonation. Very much has recently been written concern- ing what is designated "concussion of the spine" 143 —a condition which has no definite pathology, and the existence of which is mostly based on a series of vague and ambiguous symptoms. In other words, it is revealed mainly by clinical phenomena. It is alleged that its striking characteristic is the fact that it manifests its effects only after the lapse of considerable interval from the time of injury; is exceedingly insidious in its onset, but withal, may have a speedy and favorable termi- nation; that it is always followed by psychical disturbances of an emotional character, impair- ment of vision, ataxic symptoms, unsteady gait, pain in the back, headache, and a general break- ing down of health. Many distinguished authorities agree that as a result of violent physical shock, we may have a condition of the brain or cord in which there are well-marked evidences of serious pathological disturbance, and yet, after death, no gross lesions of structure are found to account for them. No one who has examined many bodies of men or women who have come to their end by a ca- tastrophe but must admit that not infrequently practically nothing can be found which unequiv- ocally accounts for death. Yet, from my own experience, I feel confidant that in many of those cases set down as spinal concussion, wherein there is no shamming, pathological changes may be discovered which will account for symptoms. It is preposterous to assume, then, whgn vio- lent and concussive force is appligd to the body, 144 that that slight, delicate cord, firmly enclosed by the dura- mater, and protected within a pow- erful, bony wall, will suffer detriment, while the exposed, friable viscera escape. Dr. B. A. Watson's experiments on animals have definitely decided this question. The spinal cord, we are told, may become anaemic. The patient, they say, has "anaemia of the cord." It is said to be a morbid condition which arises solely as a result of railroad acci- dent. A most ingenious theory has been devised to connect cause and effect in this new addition to our nomenclature of disease. The imagination and credulity of the observ- ing and thinking student are strained to the utaiost to reconcile many of the unsupported theories and allegations of its discoverers and votaries. In order to maintain the theory, and give force to reasoning, something more is demanded than hypothetical assumption and illogical conclu- sions. It is imperative and proper that the profession be enlightened on some of those moot points, which have been ignored or warily evaded by those who have written most on this mysterious disease. In the beginning, we must be con- vinced that the emotional state of terrible alarm, trepidation and suspense attendant on a railway collision are different in quality and magnitude from those which must be of frequent occurrence 145 in the carnage of battle, during the firing of heavy guns, explosions of shells, and springing of mines, from that borne by the wounded when a whole limb is torn away, or when the maimed and crippled, unable to withdraw their mangled, bleeding bodies, are ridden over, or trampled on, by the columns of advancing cavalry or artil- lery. Can the horrors of railroad calamity exceed those which accompany the crashing destruction of a thunderbolt, when it falls with destructive energy on a dwelling, lifting it off its foundation, cleaving it in two, killing outright, in an instant, one or more individuals, yet, with the survivors, how many of them suffer from spinal anaemia ? In our large cities, with their numerous, enor- mous n^odern apartment houses of great height, from which occupants or mechanics often fall in every attitude of the body, here, accordingly, the bospital surgeon will meet with every variety of spinal injury. In no case which I have ever seen of spinal injury was there ever observed by me that mental aberration which is said to con- stitute that condition which they allege to be an integral part of spinal anaemia. Next in importance to those symptoms reflect- ed through the, organ of the mind in spinal anaemia is that condition in which the spinal cord is the seat of pathological changes; or in its molecular, or vascular elements. It is not clear whether we are to understand by this, that the quantity of the blood present is di- 146 minished, or whether its nutritive, reconstructive elements are deficient, for the demands of the cord. Presuming that the pathological condi- tion can exist, as a sequelae of a violent shake of the body, there is no difiSculty in the way of ar- raying symptoms almost indefinitely, as arising from or dependent upon it. But, what proof is there from an anatomical, physiological or pathological standpoint, that such a condition is probable; that such a phase of spinal disease is possible; that the vascular supply to the spinal cord is obstructed, dimin- ished or altered, so that its nutrition is disturbed, or that its cellular elements are impoverished, while all the other organs of the body are func- tionally active? Organs stimulated by the same nervous systems, the same blood current; under the same physical laws and influenced by the physical and chemical changes. All such proof is totally wanting; nay, on the contrary, in mechanical anaemia of the organ or limb induced by the surgeon, there is no analogy whatever, into the symptoms resulting and those said to be associated with "spinal-anaemia." On ligation of the femoral arterj', as it emerges from under Poupart's ligament, we will notice a cool- ing of the limb arising from the emptying and collapse of the peripheral capillaries and loss of heat. Owing to veinous stasis and temporary diapaedesis, there is a sense of fullness in the iconnective tissues; but usually no pain, except 147 wfiere the ligature was applied and perhaps a nerve branch was injured. With the brain itself, although one or both of the carotid currents is dammed back, we may im- mediately notice the physical effect resulting; yet nothing will present itself, having the slightest analogy to this new disease. "We have other in- stances of mechanical, accidental, or pathological exsanguination in which every organ must con- tribute its share in the general loss, the spinal cord as well as others, but the local impoverish- ment of the spine, here, is not demonstrable by any special symptoms. From the foregoing, it is evident that there is absolutely nothing whatever, which should permit the continuance of a supposed pathologi- cal entity which has no substantial existence. We have no right, in these days, when instru- ments of percision are at hand, to assume the existence of a malady demonstrable, if at all, rather by therapeutic than pathological proof. It being supposed that certain functional disorders are present, which indicate impoverishment of the cord, medicines are given, which supply tone to the muscles, enrich the blood and act as a spur to the nervous system. But it is inconceivable how one can infer from therapeutic induction alone, that the spinal-marrow is the center of a morbid change, when the system responds to constitutional tonics or alteratives that act on every fibre in the organism. It would be just as illogical to argue that there was a localized anse- 148 mia in the sciatic nerve, when, through some acute malady, the bodily strength is at a low ebb. The actual pathological condition which the patient suffers from, in so-called spinal-anaemia, is unquestionably a peripheral neuroses, of a neu- ralgic character. As a matter of observation, it is well known that along the central and lateral planes of the spine there are local diseased areas, whose principal manifestations are pain and hy- peraesthesia. This pain may be localized or dif- fused; constant or intermittent. It is usually regional. It is a condition of aduk life, and is much more common in women than men. There is always a well-marked derangement of the general health. The hepatic functions are languidly performed. The patient has loss of appetite and is constipated. He is pale, leuco- cythenic and weak. If a woman, there will be menstrual disturbances. What constitutes its essential clinical differences in the sexes, ' is its local, neuralgic manifestations, its seat of selec- tion. With the male sex it is very uncommon, though when it does arise, its location will be in the lower lumbar and gluteal regions; or those parts supplied by the peripheral, or muscular ramifications of the posterior division of the lum- bar and sacral nerves. Then we will have what is designated lumbago or sciatica. With woman, these neuralgias generally radi- ate through the nerve- filaments from the anterior branches of the six upper dorsal nerves, on the 149 left side, and also, along the pelvic fibres of the anterior crural, which penetrate the ovary. Here, too, singularly, pain is most frequent in the left side. These neuralgias, intercostal and ovarian, then, are a consequence of a general debility, malaria, and functional disturbances, and are not depend- ent on traumatism of the spinal cord. These neuroses belong to that class in which the faith-healer and charletan reap a rich har- vest; or in which anyone, who can make a sud- den and positive mental impression on the mind, will meet with marked success, when internal medication fails. Many phases of this, so-called, anaemic spine, will yield to internal, reconstructive remedies, as quinine, iron, arsenic or mercury; good dieting, sea-bathing, change of air, travel, faradization, shampooing, massage, dry cupping, plasters, etc. The above may seem rather a digression from the strict text; but under the circumstances, it forms an important constituent of our theme, as it is, in reality and fact, no fanciful or imaginary picture; but is a truthful resume of what has evidently been erroneously designated "anaemia of the spine." I have endeavored to completely demolish the artificial and unstable foundation on which it rests, and tried to demonstrate that this 'Watl- roarf spinal anaemia" is a myth; but is, unhappi- ly, often a source of distress among many who have never seen a railroad. I50 Having so far considered the etiology and clinical history of those lesions and derangements attended with definite and precise pathological changes, and other maladies assumed to succeed concussive force applied to the back, it is now necessary to extend our field of inquiry from the parts which directly enter into the composi- tion of the spine, to the cavities which it poste- riorly walls in, the abdominal, thoracic and buc- cal. The abdominal cavity contains four fixed, solid organs, dependent and suspended, having . no bony encasement, and lying immediately anterior to the flexible lumbar-curve, which are frequently exposed to injury from indirect violence. It is in this situation, that is most frequently seen, destruction, limited or extensive, from trans- mitted force; as when the liver, kidney, a dis- tended stomach, bladder or gravid uterus, sufi"ers laceration or rupture. The renal organs suffer most frequently. Their juxtaposition to the spine, behind the perito- neum, when their meso-nephron, or the envelop- ing layers of fibro-cellular tissue, is dense and firmly fixes the organ in position. With the exception of grave injury of the cord, as a complication, I had never seen but two cases of injuries of the back in which there were evidences of kidney complications in ex- trinsic lesions. One of those cases, a physician, who, while aboard what is known as a cable-car, was inj ured. These cars stop and start suddenly ; 151 so that, unless managed by a competent grip- man, there are almost constant jars and starts, in their working. He had but entered the car and was advancing towards the front, when it gave a lurch forward, throwing him violently back- wards against the iron-arm of a seat. The doc- tor was unable to rise unassisted, and suffered from shock for several hours. The day follow- ing injury, he had haemoptyses and bloody urine. By proper remedial measures combined with rest, after ten days the haematuria ceased, and he was able to sit up. His recovery to health was slow, though in time he quite regained his former vigor. I have never seen hepatic disorganization, as a sequence of spinal injury, unless mortal force had been sustained. This leads me to infer either one or two things in this connection. The liver may suffer periph- eral or central disintegration, when this does not involve the large bload-vessels, with quite unique impunity, as it undoubtedly possesses within itself the property of complete and rapid repair. It may, perhaps, be partly attributable to its situation which, when attentively studied, will be found to have a configuration and posi- tion which effectually provide against extensive damage by violence, and guards it against sud- den concussive force. It has long been a matter of observation by physiologists engaged in ex- perimental work on the liver, of lower animals, and by surgeons operating on hepatic structure, 152 that if the primary gush of blood could be con- trolled, little diflBculty would be experienced; as the triple compound, circulating through the hepatic lobules, possess marvellous haemostatic properties, and plastic inflammation with rapid coaptation, was the rule. Only the free, thin-edged borders of the liver are exposed. The solid, compact mass of this organ, has a broad and intimate attachment to the inferior surface of the diaphragm. It rises high up under the shelving margins of the ribs and rests on a surface well calculated to receive and scatter concussive force, as it lies at its ante- rior, superior, and greater part of its posterior border on an air-cushion — the highly elastic and expanding lung. I know of no recorded case, wherein the spleen suffered laceration in connexion with spinal in- jury. The stomach in a distended state, lying on its posterior surface, in immediate contact with the vertebral bodies, one might expect, would easily rupture. It, however, is singularly invulnerable to physical shock. Certainly, it goes without saying, that violent concussion, sustained, through transmission, by the uterus, when impregnated more than three months, almost inevitably leads to abortion or premature delivery. The contents of the thorax, the circulatory and pulmonary organs, are seldom involved in severe injuries to the back. Very often, force brought 153 to bear will so compress the chest antero- poste- riorly as to induce multiple, costal fracture. The pulmonary parenchyma is very tough and will resist great pressure. I have never seen rupture of the heart from concussive force, through the dorsal region; although Watson has observed such a complication in his experiments. An injury of the cervical vertebrae sufiici«nt to compromise the integrity of the buccal cavity, alimentary or air-passages, must be almost in- evitably fatal. MORBID ANATOMY AND PATHOLOGY OF TRAU- MATIC SPINAL LESIONS. Morbid changes of structure, resulting from injuries born of the spine, vary according to manifold circumstances, to the quality and force applied; the time intervening from the accident; the age and condition of the patient; the extent of parenchymatous changes and degree of repara- tive effort. If the violence have been shortly followed by death, little will be noted, except extensive lacer- ation of the parts, with disorganization, partial or complete, at the seat of injury. There may be ecchymosis of the integuments and evidence of some bleeding in the underlying tissues, its quantity and quality being dependent on the de- gree of shock, heart depression, chemical and vital changes. I ha-ve frequently noted that when the bleed- ing is eccentric to the spinal- canal, the blood is commonly more or less coagulated; but when 154 within the bony rings of the vertebrae, whether intra- or extra-meningeal, is always ©f a dark liquid consistence. In those who have succumbed from lesions entailing much loss of blood, with compression of the cord resulting therefrom, I have invaria- bly found the haemorrhage located external to the meninges spinalis, and coming from the lacer- ation of the meningo-rachidian or the longitudi- nal spinal sinuses. /ntra-meniageal haemorrhage, either from the fine capillaries on the serous surface of the dura- mater or the medulla- spinal viens of the columns, horns, sulci and substance of the cord itself, I have never seen. Possibly it may occur as a pathological process in certain constitutional maladies, but as a result of an injury is not pos- sible, except in connection with mortal destruc- tion. It is well to remember that the cord, weigh- ing but an ounce and a half, has but from sixty to eighty drops of blood ever circulating in it, that it is swung in a chamber holding' nearly three ounces of fluid, by which it is surrounded on ev- ery side, and nowhere comes in contact with the bony walls which enclose it. Haemorrhage within the theca seldom is seen, post-mortem, to rise above the mid-dorsal region. The adjacent fibrous tissues are always deeply stained and occasionally the haemorrhage will find its way outward through the inter -vertebral foramina in the direction of the nerve -trunks. I have not yet seen any cases in which ad- 155 vanced changes in the direction of disintegration tion were noted after spinal bleeding. When haemorrhage has been considerable, not disappearing by absorption, we will find associ- ated with it changes attributable to congestion and inflammation. The vessels on the thecal and serous surfaces of the dura- mater are greatly distended, the subarachnoid fluid is turbid, and small flakes of lymph may be seen floating in it. In places the piamater and arachnoid are glued together, by adhesive inflammation. The cord itself is softened, and under the microscope are seen along the periphery of the white matter round cell infiltrate with leucocytes and granu- lar matter intermixed. All the membranes are markedly thickened and have a deep congested hue. The soft tissues overlying the spinal cord in spinal-meningitis, as with all other tissues which overlie inflamed serous membranes, as those of the abdomen, thorax and skull, are always considerably thickened and distended by an in- flammatory exudate. There will be found at times, evidences of bone implication, synovial destruction within the cap- sular ligaments, and sero- purulent formations. The pathological changes observed during life after spinal injuries, are important to correctly comprehend. They may, for purposes of descrip- tion, be divided into four classes: i. Eccentric lesions; 2, centric lesions; 3, organic lesions; 4, functional disturbances. 156 Eccentric lesions are those of the structure which are situated external to the spinal canal and involve the bony architecture, the motor leverage, circulatory system, mainly; and the peripheral nerves. They are dependent on pressure, tension or laceration. In the vast majority of cases, being of a trivial nature, they give little inconvenience; but when the back has borne great and considerable force, we may witness such lesion of muscle or other structure as will cause temporary or permanent loss of function. If inflammation supervene, the residuum of its deposit may undergo fibrous changes and so bind the sinewy structure together, as to occasion muscular anchylosis, pressure on the nerves or blood-vessels and amytrophic changes, in all the tissues. If the integuments and the subjacent tissues are lacerated we can readily comprehend how, through the intimate connection between the dorso- spinal and meningo-rachidian vessels, septic processes may be transported to the envel- oping membranes of the cord . Primary congestion or inflammation in the in- ter-muscular connective tissues seldom give rise to organic changes, and readily subside. But a severe injury, the widespread effects of which involve en masse all the tissues, may be followed by a low grade of inflammation, implicating the vascular supply, giving rise to a phlebitis or thrombosis of the superficial or deep veins, in this manner seriously interfering with nutrition and inducing a softening or wasting of the mus- 157 cles. The bony structure of the spine usually escapes an injury unless great violence is borne. In children, however, this immunity does not obtain, especially when tubercle is inherited. In fractures of the spine, so called, everything will depend on the direction which the fragments have taken. If the broken bone be crushed in, on the cord, we will have haemorrhage, inflam- mation and softening, while if there be slight displacements, the cord may escape. We have no proof that the bones of the spine will regen- erate; certainly if they are allied anatomically and physiologically with those of the cranium, which is claimed by some anatomists, then they are destitute of osteogenetic power. Simultaneous or consecutive osseo-arthritic changes of an inflammatory nature in the verte- bral joints seldom extend to the cartilagenous pulp between the bodies in the absence of consti- tutional cachexia. The pain along the spine in various regions according to where concussive force is applied, is dependent, I am convinced, rather on a low grade of cellulitis, involving the muscles and tendons, than a peripheral neuritis. Centric lesions of the cord, accentuated by clearly defined symptoms and resulting from trauma, are very seldom met with. Although I have seen and treated now more than one hun- dred, and fifty cases of fracture of the vault of the skull, up to the time I reported them in Oct. , 1890 (Trans. New York Medical Ass'n., 1890), and saw more than fifty fractures at the base, 158 besides very many cases of cranial injury in which spasm or paralysis followed and the pa- tients recovered; in that seventeen years experi- ence I had under my care but ten spinal injuries of an intrinsic character, so that on a reasonable calculation, in falls, blows, or collisions, it may be said that the proportional injuries of the cord with that of the brain under those circumstances, was rather less than one to twenty. As the spinal cord cannot be stretched nor sundered by concussion, we must direct attention mainly to the effects of pressure; pressure by bone, luxated or fractured, or pressure by blood; by an excess of serum, lymph, a plastic exudate or pus. Should a large spicula of bone be driven in or through the meninges, the cord is irreparably disorganized beneath it. Fractures of the lateral arches, involving the transverse processes, imply great violence, and I believe are always fatal, either immediately or remotely. The spinous processes in slim subjects being very superficial, give way to force most frequently; but owing to their inclined, overlapping adjustment and nu- merous ligamentous supports, are dislodged with difficulty. When bone pressure is moderate but constant, along with producing paralysis, involv- ing the motor or sensory nerves, or both, it gives rise to meningitis and myelitis. Before necrotic processes of the osseous structures is complete, the patient has usually succumbed. Intra-spinal haemorrhage, after severe injuries of the back, by pressure, may induce temporary 159 paralysis, meningitis or molecular degeneration of the medullary substance. The pathological changes which it induces are those characteristic of pressure exercised by a solid substance. The effused blood being confined within an air-tight chamber, in which the circulation is necessarily languid, absorption is slow and imperfect. Spinal meningitis, resulting from trauma as a primary affection, is very rare, except in the presence of fracture. . Commencing as a local and well-defined affection,' its tendency is to spread upward into the basic meninges of the brain. The peripheral sensory nerves in spinal men- ingitis are always morbidly susceptible to im- pressions, and the reflexes in the early stages of the malady give rise to intermittent or constant spasm of the muscles. Authors have in turn framed different theories to explain the predominance of one phenomenon over the other in those meningeal inflammations, when at one time we will have anaesthesia or hyperaesthesia in a limb which is motionless. They have sought to justify and prove their conclusions by experimental physiology, ascrib- ing one set of symptoms as attributable to path- ogenic changes in the an tero- lateral columns of the cord ; another, to the posterior columns ; to the grey matter and white substance, alternate- ly. These views are, however, merely specula- tive, and are lacking the confirmation of post- mortem examination. Admitting, nevertheless, their scientific accuracy, it would, as far as we i6o know, in no way aid their surgical management. Meningeal inflammation, although, as its stages merge one into the other, thus inducing pain, spasm and paralysis of the lower regions of the body, is compatible with consciousness and life, until the upper cervical segment of the spine and base of the brain are involved. Irregularity of cardiac and respiratory action, with twitching of the facial muscles, loss of speech and the power to swallow, slowly devel- oping deafness and dimness of vision, announce that the roots of the cranial nerves are involved and that the end is near. As we invariably wit- ness spinal manifestations in cerebral meningitis, so in grave spinal meningitis the vital and psy- chological functions of the brain never escape parti- cipation. Organic lesions of the cord, arising inde- pendently of constitutional causes, are infrequent. The medulla-spinalis is seldom involved in inflammatory processes without the participation of the meninges, the latter being the primary structure to take on inflammation. When the spinal marrow undergoes intersti- tial or molecular disintegration, as a result of trauma, along with constant pain over the integ- uments of the back, which often, too, is reflected along the sensory nerves into the extremities, we will see paralysis, spasm or hypersesthesia, which will correspond with that area of the cord sup- plying the affected group of muscles. As I have never seen the seat of traumatic pyelitis or pathological changes limited to the i6i cords alone, post mortem, I cannot speak from personal observation ; nor can. I find such a con- dition even mentioned by such world-renowned pathologists as Virchow, Paget, or Billroth. We must turn to medical pathology for infor- mation relative to those fine structural changes which occur in the pulpy matter, for, no doubt, like pulmonary tuberculosis and Bright's disease of the kidneys, those microscopical changes in the nerve-cylinders invariably depend on sys- temic influences solely, and not on violence of any description; hence what has been written so fully relative to pathological changes in the spi- nal marrow has but little application to surgical or traumatical lesions of it. Of the functional neuroses of the spine, their name is legion. In a surgical essay on spinal diseases, their consideration from a pathological stand would seem a work of superrerogation, if it were not claimed that many of them had their starting point in an injury. They have been designated spinal anaemia and spinal congestion, spinal concussion, etc., and one author CHam- mond on the Nervous System, page 217) has even gone so far as to further subdivide them on a physiological basis into anaemia or congestion of the antero-lateral and posterior columns. An imaginary pathology has been elaborated, with considerable detail and circumspection, to corre- spond with the views and notions of the authors, and we are told now that precise localization of spinal lesions is a matter of great simplicity. We 1 62 are informed that certain cells within the grey mat- ter and white substance degenerate and regenerate under the influence of the circulation, which, at one time, is excessive and another diminished ; that one train of symptoms is dependent on one phase of the blood supply, another on a contrary. Now, as no one has yet been able to demonstrate by an autopsy the pathological changes, if any in those functional maladies are present, the necessary proof is wanting to support these assertions. These allegations are dependent then wholly on empiricism. When subjected to the rigorous test of scientific analysis, they fade away into nothing. Very many of these spinal neuroses of a func- tional nature are chiefly hysterical, epileptic, or choreaic, probably dependent on hereditary in- fluences, sex or habit, which act through the blood. Their pathology cannot be definitely written yet, for it is not understood. Without question, however, we may rather look to the cerebral organs for the central trouble than the medulla-spinalis. THE DIAGNOSIS OF INJURIES OF THE SPINE. Before the days of I,aennec, every species of acute inflammatory afiection involving the lung, its parenchyma, its tubular structure, and serous investment, was designated "a pleurisy," and all were treated on the same general principles, by essentially the same remedial agents. But 1 63 there came forth a genius, who applied the reve- lations of physics to vital phenomena within the human body, and he taught how, by the aid of the eye, the ear and the tactile sense, we might not only recognize the different structures in- volved, but that we could, with certainty and precision, estimate the progress or retrogression of the pathological changes within them. Now, though of great value, this application of physical laws to the elucidation of pulmonary diseases, for diagnosis and prognosis, yet the late famous clinical teacher, Thomas Watson, said, in speak- ing of pulmonary disease : "It may seem para- doxical, but the very perfection of the physical diagnosis of pulmonary diseases, has often con- stituted an impediment to their treatment." Spinal diseases taken collectively, as a whole, were in the same chaotic state, at the beginning of the present century, as were maladies of the lungs before the days of I^asunec. But through the discoveries and experiments of Magendie and Bell, the functions of the nerve roots are now known, and by the aid of Brown Sequard and other experimental pathologists, we have been made aware of the special properties resident in the columns and matter of the cord, itself. Surgical pathologists have made it possible for us to differentiate the inflammations or patholog- ical changes in the various structures which en- velop the medullary cylinder, from within out- ward. And hence, to-day, not as formerly, we are enabled to speak definitely of the idiopathic 164 or traumatic affections which may occupy any area of the spine, or its organic components. It may not be always possible to effect a defi- nite diagnosis immediately after an injury of the spine has been sustained, unless very great vio- lence was applied, and the cord itself suffered direct and positive pressure from displaced bone, or fracture, as under which circumstances, complete and instantaneous paraplegia is invariably a symptom of mortal omen. At the first visit to our patient, we may find him suffering severe pain in all the joints below the sacro-lumbar articulation and upward along the lateral planes of the spine. He is unable to raise the body or elevate the lower limbs without very great difficulty, even if it is possible at all. He has perfect control of his sphincters, and sen- sation is nowhere impaired. The family, friends, or patient himself may now demand of the medical attendant informa- tion as to the nature and extent of the injury. This cannot be stated at this visit, but I feel as- sured, from my own experience in a large num- ber of spinal injuries, that, however, it will sel- dom require but a very few days before we can, with certainty, say whether the spinal marrow is involved or not. Haemorrhage, inflammation, se- rous or purulent effusion, will present symptoms of such a clear and unmistakable type, that one cannot be deceived or incapable of interpreting their clinical significance who has had experience. The most serious, but infrequent, lesions at- i65 tending violent injuries to the back, are those which have reference to the cord and its mem- branes. These are of a primary and secondary charac- ter. With the former, we are promptly apprised of direct medullary implication, by the presence of paralysis in the lower members, complete or incomplete. Primary paraplegia after the inju- ry is usually induced by pressure, which effects the disorganization of the cord, destroying its conducting power. We are not always able to precisely define the exact situation or extent of pressure, for an arch or lateral plate of vertebra may have been fractured and forced into the spi- nal canal at the time of accident, but, owing to the elasticity and strength of its connecting liga- ments, with the rebound, it is retracted away from the indented cord. And, on examination, although there may seem some slight increased mobility of a projecting vertebral spur, we can- not always assume that there is displacement. As a diagnostic aid, we might have recourse to an exploratory incision, so as to effect a more ac- curate estimate of the effect of the injury, and to guide us in the way of treatment. But, although this might be a theoretical ad- vantage in serving a dual purpose, yet practically it cannot, only in very exceptional circumstances, be regarded as a permissible procedure. Possi- bly, under extreme circumstances, might a free incision into the tissue be allowed as a therapeu- tic measure — as a diagnostic, never. 1 66 In the presence of total inhibition of the spinal or neural functions in the lower extrem- ities, we may pronounce the lesion in the spinal cord one of an irreparable character, re- sulting from direct and permanent disorganiza- tion of such a description that, even though the cord were stripped of its investments and com- pletely accessible, we are powerless in the way of instituting remedial measures. Traumatic compression, laceration, or disinte- gration of the spinal cord, accordingly, may be said to be a condition of easy diagnosis, when complete paraplegia is present. Certainly, when bone is fractured, but is not displaced, and no symptoms are present indicative of paralysis, we cannot, in the deeply buried lines of the back, always make an immediate diagnosis. It is ol little consequence under these circumstances, how- ever, that we fail to correctly ascertain the extent of lesion, for it will in no way influence remedial measures, or affect prognosis. Unfortunately, when the cord and its mem- branes become secondarily involved, some days or weeks after injury, diagnosis is attended with many perplexities. Next to osseous pressure, in producing organic changes in the spinal cord, will come haemorrhage. Paresis following hypersesthesia within twenty- four or forty-eight hours of the injury, will be suggestive of intra-spinal haemorrhage. Its vol- ume may be estimated by the extent of paralysis and the areas affected. When the viscera sup- 1 67 plied by tHe lumbar plexus show evidences of paralysis, and the sphincters of the bladder and rectum fail to act, we may assume that the efiu- sion has mounted up to the dorso- lumbar junc- tion. It may require a very nice discrimination in diagnostic tact to differentiate, at the outset, in- tra-spinal haemorrhage from meningeal inflam- mation. But the patient's exsanguinated condi- tion, the deep-seated pain from pressure, the absence of chills, acceleration of the pulse and of rising temperature, all point to the exclusion of inflammatory changes having yet occupied the rueninges. Our diagnosis of intra- spinal haemorrhage will be corroborated if, within a week's time, amelio- ration of the symptoms is present, and restora- tion of function is being gradually reestablished. Extensive haemorrhage from the dorso-rachid- ian vessels, when profuse and localized as in an intra-muscular haematoma, may be recognized as a sanguineous effusion which, in the healthy in- dividual, rapidly vanishes by absorption. Changes of an inflammatory character in the spinal cord are rnanifested by a diversity of symp- toms. First, by constitutional phenomena, which profoundly impress the nutritive processes and local conditions. The patient has fever, quick pulse, rising temperature, is thirsty, has neither sleep nor appetite. There is always pain in the back in traumatic spinal meningitis, associated with extreme pe- i68 ripheral tenderness, localized or extensive anass- thesia along tlie extensor or flexor surfaces of one or both limbs. Thus a clonic spasm, unilat- eral or symmetrical, is always present, provided there has been no implication of the medulla. When there is this association, the cord having lost its connective power below the seat of lesion, spasm will be noticed only above this limit. We are perhaps justified, in the presence of a certain set of symptoms, in assuming that we may, at the outset, be able to localize the limit of meningeal inflammation. This would seem all the more positive when, in the presence of every symptom of incipient meningitis, we suc- ceed, by the active interposition of therapeutic resource, in arresting its progress. Accordingly, we may assume that the lumbar segment, the Cauda equina, is the primary and only region af- fected when paralysis, paresis, hypersesthesia, spasm or muscular twitching, is confined to the parts supplied by the nerves whose roots are lo- cated in this district. Stifihess, pain or spasm in the muscles supplied by the lower dorsal seg- ment, those muscles animated by the lower six dorsal nerves, viz.: the deep spinal muscles of that region and the three sets of muscles which anteriorly and laterally wall in the abdomen, the external and internal, oblique and transversalis. Hence, the muscles of the back are hard, stifi" and unyielding, and it is noteworthy at this junc- ture, that the patient begins to complain of a most oppressive sense of weight and constriction 169 over the abdomen, which he compares to being drawn tightly by an encircling cord, the abdom- inal muscles pulling in an opposite direction ; or having a heavy weight resting on the prsecordia. The movable wings of the thorax are locked and fixed by an intermittent spasm of the lower intercostal muscles, and respiration is maintain- ed principally, now, by its auxiliary muscles, the cervical and scapular, with the aid of the diaphragm. Meningeal inflammation having compromised the entire dorsal district, we have anticipated it, as it were, i. e., knowing, when this area of the arch is invaded, our patient — whose mental fac- ulties remain as yet unclouded — is warned of his impending danger, and given time to prepare himself and arrange his affairs — as, with but an- other slight advance into the cervical region, the implication of post- thoracic and the phrenic nerves, when asphyxia will terminate the strug- gle. The diagnosis of cervical meningitis is unim- portant, as the general meningeal disease is wholly beyond our control, and swiftly fatal, when this area is occupied. I have seen in several fatal cases, a rather sin- gular clinical phenomenon, in the upward march of inflammatory changes. It was this: that whereas the extension of the disease, from the lumbar to the lower dorsal district, may occupy several days and be extremely insidious in its advance, but, when it was finally manifest in the dorsal segrnent, it often, within the lapse of a few hours, spread into the cervical region and quickly terminated life. CONCLUSIONS. In dealing with the foregoing subject, my aim has been to compress within a small compass as much as possible, without omitting any impor- tant detail ; but I fear, with the space at my command, in this I have but partly succeeded. Quotations and the historical part of the subject have been largely omitted. In presenting the study of spinal lesions my object has been, rather, to make it clear and comprehensive than to confine myself rigidly to any arbitrary arrangement of matter; for, re- gardless of what pains may be taken in con- structing an article, under various headings, the divisions and subdivisions are often more rela- tive than absolute. Very little or no notice at all is given to the subject of traumatic lesions of the spine, in text . books, or even encyclopaedic works on surgery ; hence, we are justified in assuming that serious injuries of this structure are rare, or else, that surgeons have given them very little attention. An attempt has been made here to isolate the complexity of lesions following severe injuries of the back, and not confound the consequences of one with the other, and to demonstrate that grave injury may be sustained in the rachidian region without any implication of the cord. Accordingly, in the light of our present knowl- edge, and after a careful study of normal struct- ure and function; the physics of force which give rise to spinal injury; experimental investigation, clinical phenomena, pathological changes and morbid anatomy, it may be definitely stated : 1. That in the vast majority of cases in which complete paraplegia immediately sets in, after spinal injury, it may be assumed, with almost positive certainty, that the medulla-spinalis has sustained a palpable lesion of its integrity, which usually ends mortally. 2. That there is no proof that mere concussive force will either simultaneously or consecutively ever lead to paralysis, without inducing well- marked and positive pathological changes in the anatomical elements of the cord. 3. Physical force and the psychological effects of fright being the same in railroad as other in- juries, there is nothing to justify the claim that there are grave lesions of the spine resulting from railroad collisions which are characteristic and peculiar. 4. There being no proof of the existence of such diseases as anaemia or hypersemia of the cord, as pathological entities, they are entitled to no place in the nomenclature of traumatic spi- nal diseases. 5. Eccentric lesionsof the back, without anyim- plication of the cord, may, nevertheless, by pres- sure on the meninges secondarily give rise to meningitis, local or general; also by infection, 172 propagated inward, ultimately effect tlie meduUa- spinalis. Those extrinsic injuries may, too, of themselves, by inducing pathological changes in the bones, cartilages, joints or muscles, occasion a permanent weakening or loss of power in the back. 6. It should be constantly borne in mind that there are always essentially two different and distinct sets of pathological lesions which result from spinal injury, viz., those involving the cord, of rare occurrence and generally fatal, and those exterior to the spinal canal, very common, but seldom giving rise to serious impediment of function. EI.ECTRO-DIAGNOSIS IN BRAIN AND NERVE INJURIES — METHODS USED AND THE APPARATUS RE- QUIRED. BY W. H. WAI/LING, M.D., OF PHILADELPHIA, PA. There are two very important propositions to be considered in connection with electro-diagno- sis, the first of which is, an adequate knowledge of electro-physics and electro-physiology, and the second, the need of the proper apparatus with which to conduct such investigation. The first proposition, or a proper understand- ing of the subjects named, is so obviously essen- tial that it is scarcely necessary to discuss it. The apparatus required for accurate electro- diagnosis merits our careful consideration. While with an ordinary faradic battery and common electrodes the approximate condition of a nerve may be arrived at, our tests will be of only a proportionate value. The batteries, meter and controller that I use here to- day were made by Mr. Otto Fleming, of Philadelphia. 174 Unfortunately, we have no definite standard in this country for our faradic coils, or for the size of our electrodes, hence the resulting confu- sion in comparative tests by different operators. It is to be hoped that the American Electro- Therapeutic Association will, at its next meet- ing, appoint a committee to consider this very important question of the standardization of our apparatus and electrodes. This is secondary in importance only to the proper standardization of the fluid extracts and tinctures of the U. S. P., which I so strenuously advocate. For electro-diagnosis three different currents are used, the faradic, the galvanic, and the franklinic. The faradic coil, which I use in diagnosis, which I here show you, is constructed upon the DuBois- Reymond principle, and grad- uated, by means of a scale, into centimeters and millimeters. The cell used to operate this coil is a modification of a grenet cell, and has an electro- motive force of one and a half volts. For my stationary coil I use two modified I,aw cells, as they are less troublesome, and are quite con- stant in action. The dry cells have not, as yet, met our expectations, when used upon the fara- dic coil. It must be remembered that the cell, in all faradic machines, is on what is termed short circuit when in use, hence the dry cell, having a tendency to rapidly polarize, soon runs down, and the battery will not work until the cell has time to recover. This apparatus is supplied with a slow, as well 175 as a rapid interrupter, and the movements of the former may be regulated to suit the operator. With a machine constructed upon this plan, the exact coil distance required to produce a con- traction, if one be obtainable, may be observed and recorded, andaccuratecomparisons made from time to time. It has been repeatedly stated that it makes no difference which of the two poles of the faradic battery are used, as the reaction of nerve and muscle is the same for both poles. I dissent from this statement. In testing a nerve with my ofiSce coil, for instance, I find that I can get a contraction with the cathode from six and a half centimeters coil distance, while seven and a half centimeters are required with the anode to get the same contraction. This from the primary coil. With the secondary coil the same contrac- tion was produced by two centimeters c.d., cath- odal closure, and two and eight-tenths of c.d. were required with the anode. The electrodes selected to make the first ex- amination should be used throughout the case. Erb recommends that the active electrode should be ten square centimeters surface measure; Stintz- ing one of three centimeters surface. Erb's in- strument is the one most generally used. Both electrodes should be covered in the same manner, preferably with absorbent cotton, wetted to the same degree, in the same solution, and be placed upon the same spots on the body at each exam- 176 ination, and the pressure should also be the same as near as possible. The size of the electrodes used make a vast difference in the amount of current required in order to produce a contraction. For the purpose of general diagnosis, the pa- tient is prepared by removing as much of the clothing as may be necessary, and, if a female, protected by a sheet or loose wrapper, and seated upon a suitable stool, upon which a wet sponge , electrode is placed, attached to the positive pole of the secondary coil of a faradic machine. The operator then takes a small, well-wetted sponge or cotton-covered electrode, attached to the neg- ative pole, and, commencing at the nape of the neck,' with a current plainly perceptible to the patient, passes down the back upon both sides of the spinal column, noting the effect produced. If there are tender spots, they will be quickly ap- parent by the patient wincing, or saying that it is painful. Note the coil distance required to locate these spots. Anaesthesia may be present in some areas, and more current be necessary to produce an impression. The tender spots indicate points of greater or less inflammation. Blood being the best conductor of all the tissues of the body, all such foci of congestion or inflammation offer less resistance to the current, consequently the greater amount will seek to pass in that direction, and cause the pain by reason of such density. Test both sides of the spinal column, and note all the reactions. 177 Pain is ijot always an indication of an inflam- matory condition, or of a lesion, as when the sponge is passed around the sides of the patient, and over the ribs, more or less pain will be ex- perienced, due to the effect of the vibrations upon the periosteum. This effect is always seen when the faradic current is used over bones which are superficial, such as the scapula, etc. As the electrode passes over the motor points of some of the abdominal muscles, they will be strongly contracted, but this is, as a rule, of no particular significance. For testing for anaesthesia, this small electrode will be found useful ; also for testing the electro- cutaneous sensibility of va- rious parts of the skin. It is made of a large number of copper wires, closely approximated, but insulated from each other, and placed in this hard- rubber case. The coil distance necessary to produce a sensation upon different parts may be compared. This electrode is to be attached to one pole of the secondary coil, and the other placed upon the sternum, and the coil distance required to produce a sensation noted. A pain- ful impression is then given, and noted, when the active electrode is removed to the opposite side of the body, and the same test made, when the two may be compared. Diminution of sensibility, or sensory irritabil- ity, is present in nearly all lesions of the spinal cord and peripheral nerves, which are serious in character, and is also present in many cerebral affections. 178 Stintzing has tabulated the normal reactions of nerves to the faradic current, a few examples of which I present. The numbers are the milli- meters on scale: Musculo cutaneous, contraction at 15 m.m. Frontal branch of facial, 25 m.m. Ulnar, at olecranon, 31.5 m.m. Crural, 38.5 m.m. Radial, 45 m.m. As no two machines are alike, the value of these tables are only approximate. THE GALVANIC BATTERY. As the galvanic battery is our sheet anchor in definite electro- diagnosis, it is essential that everything be as perfect and complete as possi- ble. The battery must be able to maintain a fairly constant potential, and for this purpose, especially for an ofiEice, or stationary battery, the I^aw or lycclanche cells are the best. The cells should be coupled in series; that is, the zinc of the first cell is attached to the carbon of the sec- ond, the zinc of the second to the carbon of the third, and so on until all are connected, the bat- tery consisting of from forty to eighty or more cells. The two terminal wires from the end cells are run to the controller and meter, thus com- pleting the circuit. This is the common arrange- ment, but I prefer to have each cell connected with my switch-board, so that I may select any number, from one up to the whole number. My reasons for such arrangement are, that where you 179 are using the whole battery, and attempt to con- trol the current by means of the rheostat, the amperage is alone controlled, and not the volt- age. In this connection, I desire to enter my protest against the use of the Edison electric- light current for medical purposes. It will charge your secondary -batteries, light your houses, your streets, and some of the cavities of the body, but I consider it unsafe and unreliable when used in place of a chemical galvanic battery. There is too much voltage, or electro motive force, which cannot be properly controlled. But there is the greater danger of a short circuit somewhere, and of the whole current being thrown in upon an unsuspecting patient, with damage to health, and possible loss of life. Such accidents have happened, and are liable at any moment to be repeated. It is also on account of the high voltage from the primary battery, when all the cells are con- stantly in circuit, that I object to the series arrangement. Suppose, for instance, that you wish to use one half of a milliampere of current upon the eye; of what possible use have you for eighty to a hundred volts of pressure? Not only is such pressure useless, but it is hurtful, if not positively damaging. This I have demon- strated again and again, to my entire satisfac- tion. For instance, one of a series of patients referred to me by Prof. Kej'ser for treatment for facial paralysis, and now under my care, com- plains of intense pain in the supra-orbital nerve. i8o with only one-half of a ma. of current, when I have fifty cells in circuit, the current- controller •being also used, but bears one ma. from twenty cells, not onl}^ without pain, but with positive comfort. A painful and sensitive nerve quickly differentiates against voltage. It seems evident that as we throw in resistance, by means of a rheostat, we increase the pressure, and my rule is to use only just a sufiBcient number of cells to give the current strength I want, and no more. All above that number is a waste of force, and a positive disadvantage. When making a diagnosis, the meter, but not the controller, should be in the circuit. DeWatte- ville's method is to place the electrodes in posi- tion, and commence with ten cells, adding cell by cell as needed, to get the reaction desired. I have tried various methods, but have gone back to DeWatteville's plan, as being the most satisfac- tory. For brain testing I have a separate series of ten cells, arranged according to my plan, and kept almost exclusively for the purpose named. Attention to polarity was seen to be of advan- tage, when using the faradic battery. With the galvanic, polarity becomes of prime importance, for the reaction of nerves is distinctive for each pole, and gives definite and unvarying results, when intelligently applied. Suppose that we wish to test the median nerves, in its most super- ficial portion, about two inches above the annu- lar ligament. With the anode, or positive pole, placed on some convenient point, place this small i8i electrode, attached .to the cathode, or negative pole, upon the nerve, and turn on the current. So long as there is no break in the current, there is no movement of the muscle, differing in this respect from the faradic current. Having say- two or three ma. the current is broken, and again suddenly closed. A quick, sharp, lightning- like contraction of a healthy muscle takes place, quickly subsiding. Upon reversing the polarity of the battery, we will find that it requires more current to get the same contraction with the anode, than it did with the cathode. Upon this has been based the following formula of normal reactions of nerve and muscles. First we have cathodal closing contraction , c . c. c . Followed by anodal closing contraction, a. c. c. and this Followed by anodal opening contraction, a. o.c. The two latter may change places and still be classed as normal, but if the anodal closing con- traction appears first, we then have what is termed the reaction of degeneration, generally expressed by the letters, R. D. There is a fourth reaction, the cathodal open- ing contraction, but it requires too strong a cur- rent to produce it, and being painful, I do not attempt it in health. Ordinarily, we will get the three contractions above noted with about the following current strength, that is in healthy subjects: Cathodal closing contraction, with 2 to 5 mil- liamp^res. I82 Anodal closing contraction, with 5 to 8 mil- liamperes. Anodal opening contrsction, with 5 to 8 mil- liamperes. These numbers are only approximate, as much depends upon the condition of the subject, whether there be much or little adipose tissue to deal with. To illustrate the reactions, we will take a case of injury to the arm, the result, we will say, of a railway accident. The patient states that the arm has been rendered useless. Having bared both arms, and the chest of the patient, place a large,' well wetted sponge, or other electrode, upon the sternum, connected with the positive pole of the faradic battery, and with the small negative electrode, test the well arm first, noting the coil distance necessary to produce a contraction. Use the secondary coil in such testing. Next test the diseased arm, noting, as Bramwell tersely puts it: "i. Whether a muscular contraction is pro- duced or not. 2. If a contraction is produced, what is the minimum strength of current required to produce it, and whether the character of the contraction is in any way altered from the normal. 3. The strength of current and the rapidity (whether slow or quick) of the interruptions re- quired to produce the maximum amount of mus- cular contraction." It is better, in all such i83 cases, to test corresponding groups of muscles, as above stated, so as to compare results. Next test with galvanic current and note "i. Whether a muscular contraction is pro- duced or not, 2. If a contraction is produced [a] what is the minimum strength of current required to pro- duce it; \_l>] the order of the polar reactions; [c] the character of the contractions, whether healthy or not; [rf] the strength of current re- quired to produce tetanus; [e] whether the con- tractions are more easily excited by slow or quick interruptions of the current." In order to get the most satisfactory reactions, the muscles must be relaxed. If you get con- flicting or confusing reactions, and the patient is resisting the current, he must be placed under ether, or some other anaesthetic, when the prop- er reactions will readily appear. If, however, you find the normal formula re- versed, that is, if anodal closing contraction comes before cathodal closing contraction, you may be assured that there is degeneration, as the reactions of degeneration cannot be simulated. We are here dealing with a peripheral paraly- sis, and the reaction of degeneration appears, because the nerve has been separated from its trophic center in the cord. I herewith present a graphic representation of the normal reaction of a nerve under galvanic stimulation. i84 4 s<„ II If »,° i!a $1 a p a; u aiBW "3 a < ■0 n " S a. 2 «,2 a a als" ^ ...-ga E 2 aS ota aS IE •J 3 h a a ll :l sa a o ft E a l-< i a i E 2| > a; m .2 2 wi a 1 2 1 cug 5 ° a u-a £-3 ta i.2 £■« m a. 3 l^a E