l>tate Ql0Ucge of Agriculture At (Qocnell UninecsUg Jltl)ata. ^. $. ICibratg RS 157 ss""*" ""'™''*'*>' '-'""'^y '*tmmmmm!}S^.,^l "'"^s and solutions Cornell University Library The original of tliis book is in tine Cornell University Library. There are no known copyright restrictions in the United States on the use of the text. http://www.archive.org/details/cu31924003468208 NURSES HANDBOOK OF DRUGS AND SOLUTIONS By JULIA C. STIMSON, R.N. Vassar A.B. Graduate o£ The New York Hospital Training School for Nurses Formerly Superiniendefit of Nurses Harlevn Hospital of Belleviie and A Hied Hospitals Netv York City FOURTH PRINTING WHITCOMB & BARROWS BOSTON 1912 Copyright 1910 By Julia C. Stimson PREFACE This book has two objects : first, to present as much Materia Medica, in a simple and useful form, as is essential for a nurse to know ; and second, to omit as far as possible all that is not essential, albeit interesting and useful. It is not a reference book, but if mastered as a text-book it is hoped that the information it contains will enable nurses to have a sense of security and familiarity in the handling of drugs that will be of use and satisfaction to them in the practice of their profession, and also, that by its aid they ■will have no difficulty in preparing themselves for their examinations on the subject for State Registration. It is recognized that the Practical Classification is open to criticism as illogical and arbitrary. But it has not been made without reason. A study of many text-books of Ma- teria Medica for medical students and those for nurses has shown the great variety and the complexity of the classifi- cations of drugs as therein presented. Some authors believe that it is impossible properly to classify drugs according to their action, as the majority of drugs have several equally important actions ; therefore, they arrange the drugs alpha- betically. Some classify according to the physiological action ; some according to the therapeutic uses. The last arrangement is accepted by most writers as the best method. It is, however, a somewhat complicated and much subdi- vided method. The arrangement in these pages has worked itself out from a series of lessons based on the most com- mon and important drugs which are administered by nurses in the wards of large general hospitals. They fall into IV PREFACE groups classified according to their importance and thera- peutic action. It is, of course, as impossible to draw a line between the essential and the nonessential as it is to make a list of drugs arranged in sequence according to their power and importance. Such things are a matter of opinion and somewhat of locality. But a practical, easily memorized arrangement should be tried. A nurse's use of Materia Medica is limited, and lies along diflferent lines fiom the uses to which a doctor applies his knowledge of the subject, as it is beyond her province ever to prescribe. Still, it is essential that a knowledge of the powerful and important drugs be a part of her working equipment, that she may be able to afford the intelligent assistance to the physician, on behalf of the patient, that is required of her. To make such a knowledge an easy acquirement, this book has been prepared for use as a practical handbook, as well as a classroom manual. CONTENTS PAGE Part I Definitions, with Examples i Common Preparations of Drugs, with Examples ... 6 Commonest Methods of Applying Drugs .... 8 Considerations for the Modification of Dosage ... 9 Part II Tables of Weights, Measures and Solutions . . . 11 Rules for Solutions, with Examples 14 Part III Classification and Study of Drugs 21 Antidotes and Treatment for Poisoning • • • • SS Part IV Common Formulae 59 Latin Phrases and Abbreviations 63 Part V Antitoxins, Vaccines and Sera 67 PART I DEFINITIONS, WITH EXAMPLES Alkaloids are the organic basic substances existing in many plants, or the " active principles " of vegetable substances. All are powerful and are given in minute doses. Their Latin names always end in in. Strychnin is one of the alkaloids of Nux Vomica, and Atro- pin of Belladonna. Alteratives are remedies which alter the course of conditions, particularly in chronic diseases. Mercury Arsenic Colchicum Cod-liver Oil lodin Sulphur Phosphorus Analgesics or Anodynes are remedies which relieve pain. Opium Chloral Belladonna Atropin Acetanilid Phenacetin Local Anodynes are remedies which lessen. the sensi- bility of the skin and mucotis membrane when applied locally. Aconite Alcohol Volatile Oils Menthol Zinc Oxid Anesthetics are remedies which cause temporary in- sensibility. General : Chloroform Ether Nitrous Oxid (Gas) Local : Cocain External Cold Ether Phenol Menthol 2 NURSES HANDBOOK OF Antidotes are agents which prevent the action of poisons. Antiperiodics are remedies which oppose the periodic return of symptoms. Quinin Arsenic lodin Salicylates Antipyretics are agents or measures which reduce fever. Coal-tar Antipyretics Salicylates Quinin Aconite Baths, Sponges, etc. Cold Drinks Antiseptics are agents which arrest the development of bacteria. Silver Nitrate Phenol Lysol Creolin Pot. lodid Alum Acetate Naphthol Quinin Hydrogen Peroxid Potassium Permanganate Antispasmodics are agents which arrest or cure spasms or convulsions. Stramonium Opium Asafetida Chloral Belladonna Valerian Astringents are agents which produce contraction of muscular fiber and lessen discharges. Acids Alum Lime Phenol Tannic Acid Bismuth Silver Nitrate Zinc Sulphate Cardiac Sedatives are agents which lessen the heart's power and energy. Aconite Veratrum Viride Hydrocyanic Acid Bromids Pilocarpin Cardiac Stimulants are agents which increase the force and frequency of the pulse. Strychnin Digitalis Adrenalin Caffein Nitroglycerin DRUGS AND SOLUTIONS 3 Carminatives are agents which expel gas from the stomach and intestines. Asafetida Camphor Ether Chloroform Ginger Mustard Oil of Peppermint Cathartics or Purgatives are agents which cause in- testinal evacuation. Cerebral Depressants are agents which reduce the functions of the brain. Bromids Chloral Opium Aconite Most Hypnotics and Narcotics and a few Anes- thetics. Cholagogues are remedies which increase the quantity of bile secreted. Calomel Aloes Podophyllum Rhubarb Elaterin Demulcents are substances which soothe and protect the parts to which they are applied. Glycerin Starch Flaxseed Gelatin Honey Barley White of Egg Olive Oil Diaphoretics or Sudorifics are remedies which produce sweat. Alcohol Ether Pilocarpin Opium Aconite Salicylates Tobacco Disinfectants are agents which kill bacteria. Fire Moist heat at 212° F. Dry heat at 302° F. Bichlorid of Mercury Sol. i : 1000 Potassium Permanganate Sol. i : 100 Formaldehyd Sol. i : 33 Creolin Sol. i : 100 Lysol Sol. I : 100 Acetic Acid Sol. i : 14 Chlorid of Lime Carbolic Acid i : 20 4 NURSES HANDBOOK OF Diuretics are agents which increase the secretion of urine. Potassium Salts, Sodium Salts, Magnesium Citrate, Alcohol, Caffein, Calomel, Convallaria, Strophan- thus. Digitalis. Ecbolics or Oxytocics are agents which produce uterine contractions. Ergot Quinin Strychnin Oil of Rue Emetics are agents which produce vomiting. Alum S-30 grs. Mustard (Sinapis) dr. 1+ Zinc Sulphate 10-30 grs. Ipecac 10-30 grs. Tartar Emetic 1-2 grs. Apomorphin (hypo) gr. jJ^ Tepid water in quantity Salt Emmenagogues are remedies which restore the men- strual function. Ergot Iron Strychnin Pulsatilla Cantharis Excitants are agents which increase the function of the brain and spinal cord. Alcohol Ammonia Coffee Tea Ether Strychnin Tobacco Camphor Expectorants are agents which promote the excretion and expulsion of mucus from the bronchial mem- brane. Apomorphin and other emetics Benzoin Ammonium Chlorid and Carbonate Strychnin Licorice Acids Sulphur Hematinics are remedies which increase the hemoglobin of the blood. Arsenic Iron Cod-liver Oil DRUGS AND SOLUTIONS 5 Hypnotics are remedies which produce sleep. Paraldehyd Bromids Veronal Trional Opium Hyoscin Alcohol Chloral Mydriatics are remedies which cause dilatation of the pupil of the eye. Atropin Cocain Hyoscyamin Homatropin Myotics are remedies which cause contraction of the pupil of the eye. Eserin Pilocarpin Nicotin Narcotics are agents which lessen sensibility. Alcohol Opium Belladonna Chloral Phenol Respiratory Depressants are remedies which decrease the number of respirations per minute. Opium Aconite Chloral Alcohol Respiratory Stimulants are agents which increase the number of respirations per minute. Strychnin Atropin Caffein Cold Douche Electricity Rubefacients or Counter-irritants cause reddening and irritation of the skin when applied locally. • Capsicum Mustard Alcohol Turpentin lodin Cantharides Sedatives are agents which allay irritation, irritabihty and pain. General Sedatives include na;rcotics and anesthetics. Local Sedatives include local anodynes and 'local anesthetics. ' ' ■ i Sialogogues are agents which increase the flow of saliva. Ether Mustard Ginger Capsicuin Pilocarpin 6 NURSES HANDBOOK OF Stomachics or Gastric Tonics are agents which in-' crease the appetite and promote digestion. Dilute alkaline solutions before meals Arsenic Alcohol and Ether in small doses Pepper Nux Vomica Styptics or Hemostatics are agents which arrest bleeding. Acids Adrenalin Alum Local heat or cold Urinary Acidifiers are agents which make the urine acid. Benzoic Acid Urotropin Urinary Alkalinizers are agents which make the urine alkaline. . Potassium Salts Vegetable Diet COMMON PREPARATIONS OF DRUGS, WITH EXAMPLES Aqua — a solution in water of volatile substances. Aqua Rosae, Aqua Ammonise, Aqua Chloroformi, Chloroform Water Cerate — a preparation for external use, the base of which is wax, lard or petrolatum. Camphor Cerate Decoction — a solution made by boiling substances in water. Tea, Decoction of Dandelion Elixir — a sweetened aromatic alcoholic preparation. Elixir of Gentian, of Ferric Chlorid, of Pepsin, etc. DRUGS AND SOLUTIONS 7 Emulsion — a preparation in which an oily substance is kept suspended in water by means of some viscid substance, such as yolk of egg, gum acacia, etc. Emulsum Olei Morrhu'se, Emulsion of Cod-liver Oil Extract — a solid preparation of a drug made by evap- orating a solution of the drug. Extractum Opii, Extract of Opium Fluid Extract — a concentrated solution of a vegetable drug, usually a tincture, of definite strength (a minim of every fluid extract being the equivalent of a grain of the drug). Fluidextractum Ergotse, Fluid Extract of Ergot, Fid. Ext. Nucis Vomicae, Fluid Extract of Nux Vomica. Glycerite — a mixture of a medical substance with Glycerin. Glyceritum Acidi Tannici, Glyc. Ferri, Iron Glyc- erite. Infusion — a solution of a vegetable substance in water without boiling. Infusum Digitalis, Infusion of Digitalis. Inf. Sennae Compositse, Compound Senna Infusion. Liniment — an oily liquid preparation to be rubbed upon the skin. Linimentum Camphorse, Camphor Liniment. Chlo- roform and Belladonna Liniment, etc. Liquor — a solution in water of a non-volatile substance. Liquor Calcis, Lime Water, Liq. Potasii Citratis, Solution of Potassium Citrate. » NURSES HANDBOOK. OF Mixture — a preparation in which two or more liquids are mixed together. Mistura Rhei et Sodii, Rhubarb and Soda Mixture, Mistura Glycyrrhizae Compositae, Compound Licorice Mixture (Brown Mixture). Ointment (Unguentum) — a mixture of a medical agent in a basis of lard or petrolatum. Ung. Acidi Borici or Boric Acid Ointment, Ung. Hydrargyri or Mer- curial Ointment. Spirit — an alcoholic solution of a volatile substance. Spiritus iEtheris Nitrosi or Spirits of Nitrous Ether. Sp. Frumenti (Whisky), Sp. Ammonias or Spirits of Ammonia. Suppository — a solid body containing a medical sub- stance for insertion in the vagina, rectum or urethra. Suppositoria Glycerini, Glycerin Suppositories, Opium or Belladonna Suppositories, etc. Tincture — an alcoholic solution of a non-volatile medic- inal substance (with the exception of Tr. of lodin, for lodin is volatile). Tinctura Aconiti, Opii, or Tincture of Aconite, Opium, etc., Tr. Nuc. Vom. or Tincture of Nux Vomica. Wine — a tincture with white wine as a base. Vinum Ferri or Wine of Iron, Vinum Colchici Seminis or Wine of Colchicum Seed. COMMONEST METHODS OF APPLYING DRUGS I. To the Skin Inunctions (Oils, Liniments, Ointments, etc.) DRUGS AND SOLUTIONS 9 Contact without rubbing (Baths, Blisters, Cooling Applications, etc.) 2. To the Mucous Membrane (Gargles, Sprays, Douches, etc.) 3. To Wounds and Diseased Tissues (Antiseptic Powders, Ointments, Solutions, etc.) 4. To the Respiratory Tract Inhalation of fumes or vapors 5. To the Circulatory System Hypodermic Injection Intravenous Infusion Hypodermoclysis 6. To the Alimentary Canal By Mouth (Pills, Powders, Solutions, etc.) By Rectum (Enemata, Suppositories, etc.) CONSIDERATIONS FOR THE MODIFICATION OF DOSAGE Age. Rule for calculating the dose for a child when the adult dose only is known. Take the age (in years) of the child as the numer- ator and the age plus twelve for the denominator. The resulting fraction will be that part of the adult dose to be given. (Example : Age 3 years, ■3 2 1 — or — , which is part of adult dose 3+12 IS 5 to be given.) Weight, Heavy, muscular persons require larger doses, as a rule, than those who are delicate. 10 NURSES HANDBOOK OF Sex. The dose for a woman is usually smaller than that for a man. Idiosyncrasy. Certain individuals have a peculiarity of constitution whereby they are affected by a drug or agent in a manner entirely different from the ordinary. Acquired Immunity. The injection of certain toxins or drugs in gradually increasing doses at proper intervals can often be borne without reaction. Physical Condition. In illness the dose is increased according to the severity of the disease or the urgency of the case. Thus very large doses of Morphin are tolerated in severe pain, because the action of the drug is spent in overcoming the pain. In cases of great shock larger doses of stimulants are given than would be required in conditions of slight shock. Pregnancy, menstrua- tion and lactation modify the doses of some drugs. Accumulative Action. Some drugs are excreted from the body so slowly that the whole of one dose is not excreted before the next dose is given, conse- quently the amount present in the body gradually increases. (Examples : Arsenic or Digitalis.) Habituation. Larger doses than usual are often neces- sary if the individual has become accustomed to any drug taken for a protracted time. Method of Administration. One dose by hypodermic equals, approximately, two doses by mouth and four by rectum. PART II WEIGHTS, MEASURES AND SOLUTIONS Apothecaries' or Troy Weight Gr.xx, or 20 gr. = i scruple (9) 3iii, or 3 sc. ^ I drachm (5) Gr.lx, or 60 gr. = i drachm (5) Sviii, or 8 dr. ^ i ounce (g) Sxii, or 1 2 oz. ^ I pound (lb) Apothecaries' or Wine Measure m.lx, or 60 minims = i fluiddrachm Sviii, or 8 fldr. = i fluidounce Sxvi, or 16 floz. = I pint Sxxxii, or 32 floz. =-- 1 quart Metric System Unit of Weight = i gramme Unit of Length = i metre (39+ inches) Unit of Volume = i cubic centimetre (c.c.) I c.c. of water weighs i gramme (at 4° C.) Volume I c.c. = I gm. of water in weight 1000 c.c. = 1000 gms. of water (or I litre = i kilo (kilogramme) in weight) = lb. 2.7 Troy, or lb. 2.2 Av. W^ eight I gramme or Unit of Weight 1000 grammes = kilo 12 NURSES HANDBOOK OF Length I metre or Unit of Length I GOO meters = i kilometer Approximate Equivalents IS grains = i gramme IS grains = i c.c. IS minims = i c.c. I grain is equivalent to i minim 4 grammes = i fldr. 4 c.c. ^ I fldr. 30 c.c. = I ounce (32 actually) 1000 c.c. ^ I litre or quart 1 fldr. = I teaspoonful, or 4 c.c, or 4 grammes in weight 2 fldr. = I dessertspoonful, or 8 c.c, or 8 grammes in weight 8 fldr. = 2 tablespoonfuls, or 30+ c.c, or 30+ grammes in weight 2 floz. = I wineglassful, or 60+ c.c, or 60+ grammes in weight 4 floz. = I teacupful, or 120+ c.c, or 120+ grammes in weight 8 floz. = I glassful (filled to brim), or 240+ c.c, or 240+ grammes in weight Note I. I : 1000 solution always means is grains to the quart (-jlj-^). Note II. I : 100 or i^ solution always means 5 grains (or s minims) to the ounce. (Literally 4.8 grains.) DRUGS AND SOLUTIONS 13 Normal Saline Solution (-^ oi 1%) 90 grains of salt to the quart (Note I) 6 grammes (by weight) to the quart I J drachms or a rounded teaspoonful to the quart For a jSj. of ifo solution use 135 grains to the quart, or approximately a drachm to a pint (70— grs.) Brief Solution Table (Using 5 grains to the ounce for a i^ solution or Note II) For 1000 use dr.i to a gal., or mxv to i qt. (J^^ 100 use dr.ii, mxl to i qt. 100 use dr.i, mxx to i pt. 50 use dr.v, mxx to i qt. 50 use dr.ii, mxl to i pt. 25 use dr.v, mxx to i pt. 20 use dr.xiii, mxx to i qt. ^Ig- of if), or Jj^ = I : 1000 i of 170, or i^ = i : 500 1 of if, or i^ = i : 200 if=i: 100 2f= 2 : 100 or I : SO 3^= 3: 100 or I : 33* 4f= 4- 100 or I : 25 sf=s- 100 or I : 20 lof = 10 : 100 or I : 10 2of = 20 : 100 or I : 5 25^ = 25 : 100 or I : 4 So^ = 50 : 100 or I : 2 100^ = 100 : 100 or I : I (a pure drug) 14 NURSES HANDBOOK OF Rules for Solutions Rule I, To make a weaker from a stronger solution. Divide the strength desired (or the weaker solution) by the strength you have (or the stronger solution), and then divide the amount wanted by the first result. First be sure that the two strengths you are working With are in the same terms. For instance, if one strength is in f> (per cent) and the other in proportion, as I : 20 or I : 1000, change the per cent to proportion. (See table, page 13.) Examples I. Given a 5^ (or i : 20) solution of Carbolic Acid to make 3 quarts of a yf> (or i : 200) solution. (Rule I.) 20)200 ID 3 qts. -^ 10 ^ 96 oz. -^ 10 ^ 9^^ oz. -l-^ oz. X 8 = 4f drs. | dr. X 60 = 48 m. Ans. Six, 5iv, m.xlviii. II. Given a 2^ Silver Nitrate solution to make I gallon of a I : 4000 solution. (Rule I.) 2^ = I : 50 50)4000 80 I gal. = 4 qts. = 128 oz. = 1024 drs. 80)1024(12 drs. (:= Si, 5iv) 80 224 160 64 ^ -^ X 60 = 48 m. 80 Ans. Si, 3iv, m.xlviii. DRUGS AND SOLUTIONS 1 5 III. Given some pure drug. (Rule I.) (A pure drug equals loo^ or i : i.) For instance: To make 2 quarts of a i^ solution of Acetic Acid, i^ ^ I part of Acetic Acid to 100 parts of water. 2 qts. = 64 oz. =: 512 drs. Since there is to be i part of Acetic Acid to every ICO parts of water, we must give as many drachms of Acetic Acid as there are hundreds in 512 drachms, which is Syjj^o drachms. tVo X 60 = 7 m. Ans. Use 3v, m.vii of Acetic Acid for 2 qts. of ifo solution. Another way of working out this problem is to use Note II. 5 grs. to the oz. is a i^ solution. 2 qts. = 64 oz. 64 X S grs. = 320 grs., or the amount necessary for 2 qts. 320 grs. = 5 drs. and 20 m. (Divide by 60.) (The difference in the minims in the two methods is due to the fact that 5 grains to the ounce for a i^ solution is an approximate figure. Actually it should be 4.8 grains, but 5 grains is close enough for all practical purposes.) IV. Given a bottle of gsf> Carbolic Acid. (Rule I.) (A pure drug equals 100^ or i : i.) (gSf) Carbolic Acid is considered Pure Carbolic because 5^ water or glycerin is used to keep it in solution.) 1 6 NURSES HANDBOOK OF To make 3 pts. of a 5^ solution. 5^0 = 5 : 100 or I : 20. 3 pts. = 48 oz. Since there is to be i part of Carbolic to every 20 parts of water we must use as many ounces of Carbolic as there are twenties in 48 ounces, which is ^27 ounces. ^V = I X 8 drs. = if = 3i drs. ^ X 60 m. = 12 m. Ans. Sii, 5iii, m.xii. This problem can also be solved by the second method used in Example III, using Note II. For I ounce of a i^ solution we will need S grains. For I ounce of a 5^ solution we will need 25 grains. For 3 pints or 48 ounces we will need 48 times 25, or 1200 grains or minims, which, divided by 60, equals 20 drachms. 20 drs. = 2 oz. and 4 drs. Rule II. To estimate a dose of a different frac- tional part of a grain from the drug on hand. Multiply the denominator of the fraction of the solution on hand by the number of minims containing it, and divide the result by the denominator of the fraction required. Examples V. If m.x = gr. -^-^, how would you give gr. -^-^ ? If m.x = gr. ^Ijj, m.i will contain ^-^ of -^^ or -^^-^ of a grain. It will then take 300 minims to contain I grain. It follows then that if m. 300 contains i grain, ^ of a grain will be contained in ^^ of 300, or 4 minims. Ans. m.iv = gr. -^-g. DRUGS AND SOLUTIONS 1 7 VI. If m.x = gr. ^-^, to give gr. -^■^. (Rule II.) 200)300(1^ 200 100 200 Ans. m.iss = gr. ^^-g-. How to give a fraction of a minim. Double the dose, add an equal amount of sterile water, then give half of that whole amount. To give m.iss take m.iii, add m.iii of sterile water and of this 6 minims give 3 minims (m.iii). VII. From a bottle of 15 grain tablets of Bichlo- rid of Mercury how would you make 4 quarts of a I : 1 0000 solution ? IS grs. to I qt. is a I : 1000 solution (Note I). 4 X 15 grs. or 60 grs. to 4 qts. is still a i : 1000 solution. I : loooo is 10 times weaker than a i : 1000 solu- tion, therefore we need, for 4 qts. of a i : lOOOO solution, ■J^ of 60 grs. or 6 grs. The tablets are 1 5 grains. To obtain 6 grains, dis- solve I tablet in i drachm of water and take -f-^ of the drachm, or -f-^ of 60 minims, which equals 24 minims. If you have a capsule or tablet containing a larger dose than the dose ordered. Dissolve it in water and give the required fraction of the solution. For instance : Given a capsule containing S grains of Soda Bicarb, to give 2 grains. Dissolve in water and give I of the solution. 1 8 NURSES HANDBOOK OF VIII. Given a solution of Camphor in Oil 20^, to give 5 grains. 20^ = 20 : 100 or I : 5 or I gr. in 5 minims. Therefore to give 5 grains take 25 minims. SOLUTIONS, Continued Lysol — A preparation of Carbolic Acid. Used in i : 200 to i : 50 solutions for vaginal antisepsis. Lime Water — Gastric sedative. Prepared by dissolving unslaked lime in sterile water. Use i lb. to i qt. of water. Allow to stand for a few hours, then filter. Keep in a cool place, well corked. Chlorid of Lime Solution — For disinfecting evacua- tions. Use I lb. to I gal. of cold water. Mix in a wooden pail. Potassium Permanganate — Antiseptic irrigations and for stomach washings. Used in i : 500 to i : 5000 solutions for irriga- tions and stomach wash, and in i : 50 to i : 1000 solutions for gargles, sprays, etc. Aluminum Acetate — For antiseptic dressings and infected wounds, etc., Acetate of Lead 38 grs. Alum 24 grs. Water i qt. DRUGS AND SOLUTIONS I 9 Formalin — A solution of formaldehyd gas in water. Usually 40^. Used in a i : 50 solution for disinfecting wounds and instruments, in a i : 25 solution for disinfect- ing stools and a i : 400 solution for irrigating purposes. For Fumigation. Sufficient formaldehyd gas will be generated for 1000 cubic feet of air space by pouring over 6\ oz. of potassium permanganate crystals, i pint of formalin (40^). Peroxid of Hydrogen — For cleaning pus cavities and necrotic tissue. Oxygen is liberated and pus is destroyed. For pus cavities use pure. For gargle dilute \-\. Keep in a cool place. Bichlorid of Mercury — Efficient disinfectant, except for instruments, which it corrodes ; white goods, which it discolors ; and feces and sputum, which it does not disinfect on account of the albuminous material and ammonia usually present in excreta, which decompose the drug. Used in a I : 5000 solution for many antiseptic purposes and in a i : 1000 for disinfecting. Carbolic Acid or Phenol — Antiseptic and disinfectant. Pure Carbolic requires about 5^ of water or glyc- erin to keep it in solution. In making solutions hot water must be used, and the bottle must be 20 NURSES HANDBOOK OF shaken until all globules disappear, as they will bum any tissue with which they come in contact. Used in a I : 20 solution for disinfecting instru- ments, clothing, utensils and excreta and in a I : 100 or 200 solution for antiseptic dressings. Boracic Acid or Boric Acid Saturated solution is 4^. Antiseptic and soothing in dilute solutions. Used in I : 50 solutions for eye and ear irrigations. Carron Oil or Lime Liniment. -^- Equal vxriumes of lime water and linseed oil. For local use, particularly for burns. PART III PRACTICAL CLASSIFICATION OF DRUGS * Drugs upon which emphasis has been laid. I. Heart Stimulants a. Artery Constrictors *Strychnin *Adrenalin •Digitalis *Caffein Camphor b. Artery Dilators •Nitroglycerin Sodium Nitrite *Amyl Nitrite Sweet Spirits of Nitre II. Heart Depressants •Aconite Colchicum •Veratrum Viride III. Narcotics and Hypnotics a. Hydrocarbon Narcotics •Alcohol Alcoholic Beverages •Ether Nitrous Ether •Chloroform Hoffman's Anodyne b. *Opium Group Opium Paregoric Morphin Codein Laudanum Heroin c. Hypnotics •Chloral Veronal Chloralamid Paraldehyd Sulphonal Hedonal Trional Amylene Hydrate 22 NURSES HANDBOOK OF d. Alkaloidal Hypnotics Hyoscin Morphin IV. Respiratory Stimulants *Atropin Hyoscyamus Strychnin Stramonium *Hyoscin V. Motor and Respiratory Depressants *Eserin Bromids VI. Coal-Tar Products a. Antipyretics Acetanilid Aspirin Ammonal Migranin Antikamnia Phenacetin Antipyrin b. Antiseptics Benzoin Phenol-camphor * Carbolic Acid Picric Acid Creosote Lysol Creolin *Salicylic Acid Guiacol Salol VII. Diuretics and Diaphoretics *Scoparius Pot. Citrate A. B. C. Diuretic *Pilocarpin Pot. and Sodium Tartrate Squill Seidlitz Powder Senega Pot. Acetate Apocynum Urotropin Caffein VIII. Cathartics a. Laxatives and Aperients b. Simple Purgatives DRUGS AND SOLUTIONS 23 c. Drastic Purgatives d. Cholagogue Purgatives e. Saline Purgatives IX. Alteratives *Arsenic Calcium Chlorid *Iron Sodium Phosphate *Iodin Urotropin X. Metals Alum Cerium Lead Zinc XI. Intestinal Antiseptics Salol Urotropin Salicylates Creosote XII. Intestinal Astringents Bismuth Subnitrate Iron Antimony Arsenic Bismuth Copper Gold Iron Manganese * Mercury Silver Silver Nitrate Alum Opium XIII. Antispasmodics Asafetida Valerian XIV. Acids Acetic Hydrochloric Hydrocyanic Nitric Sulphuric Tannic Bismuth Subgallate Tannic Acid 24 NURSES HANDBOOK OF PRACTICAL CLASSIFICATION OF DRUGS I. Heart Stimulants a. Artery Constrictors. Strychnin (Nux Vomica) Source : Strong alkaloid from the East Indian plant, Nux Vomica. Action : Cardiac, Respiratory, Spinal and Cerebral Stimulant. Stomachic. Externally and locally poisons vermin. In the mouth has bitter taste. Increases flow of saliva and of gastric juices (bitter tonic effect). Pro- motes peristalsis and increases appetite. Has no direct action on the heart and respiratory system, but acts through the nervous system, which it stimulates. Contracts and tones arteries and veins. Raises blood pressure. Increases respiration. Steadies and holds heart in check. Lowers pulse. Has accumulative effect. Preparations and Dosage : Strychnin Sulphate or Nitrate, dose, gr. ^^^ to -^-^ Extract of Nux Vomica, dose, gr. \ to i Fluid Extract of Nux Vomica, dose, m.i to iii Fluid Extract contains i^ Strychnin Tincture of Nux Vomica, dose, m.v to xx Tincture of Nux Vomica contains J^^ Strychnin Wine of Nux Vomica, dose, oz. A DRUGS AND SOLUTIONS 2$ Symptoms of Overdosage : Overexcitation of nervous system. Restlessness and twitching. Convulsions, with relaxation be- tween spasms, which may be brought on by the slightest touch or sound, owing to the intense irritability of the nervous system. Rigidity. Opis- thotonos. Staring eyes. " Risus Sardonicus," or sardonic grin. Mind usually clear. Death due to paralysis of respiratory muscles. Antidotes and Treatment : Emetics (Zinc Sulphate). Lavage (Potassium Per- manganate). Tannic Acid. Chloroform to control convulsions. Amyl Nitrite inhalations. Chloral and Sodium Bromid by rectum. Catheterization. Quiet. When giving Strychnin in any form restlessness and twitching are always to be watched for. Strychnin is more effectual in old people. One of the differences between Strychnin and Tetanus convulsions is that in Strychnin poison- ing the jaw is one of the last parts to be affected. Digitalis Source : The Purple Foxglove. Action : Cardiac Stimulant, Gastrointestinal Irri- tant and Diuretic. Is a sharp irritant subcutaneously. Has a direct action on the heart muscle. Stimulates contractil- ity. Increases force and lowers rate of pulse. Stimulates and contracts blood vessels. Has a 26 NURSES HANDBOOK OF powerful checking influence on the heart. In- creases the amount of urine excreted. Has accu- mulative effect. Preparation and Dosage : Extract of Digitalis, dose, gr. ^ to i Fluid Extract of Digitalis, dose, m.i to m.iii Tincture of Digitalis, dose, m.v to m.xxx Infusion of Digitalis, dose, dr.i to iv Symptoms of Overdosage : Slow pulse, becoming rapid. Violent vomiting. Vertigo and pain. Dilated pupils and staring eyes. Diarrhea. Irregular, weak pulse. Rapid, feeble respiration. Delirium, stupor and convulsions. Final paralysis of heart. Antidote and Treatment : Emetics and cathartics. Tannin in large quan- tities. Rest and quiet in a horizontal position. Ammonia, Brandy, Strychnin and Atropin for stimulation. Digitalis is bitter, nauseating and may interfere with digestion. May also cause sleeplessness and fainting. Adrenalin Source : The Suprarenal Glands of sheep. Action : Cardiac Stimulant, Vasoconstrictor and Hemostatic. Is alkaloidal in character. Stops local bleeding and checks secretions. Contracts arteries. Increases the force and decreases the rate of pulse. Raises blood pressure. Increases DRUGS AND SOLUTIONS 2/ arterial tone and stimulates the heart. The most powerful hemostatic and astringent known and a stimulant of great energy. An ideal stimulant for rapid action in shock, collapse and cardiac failure. Preparation and Dosage : Adrenalin Chlorid (i : looo solution), dose, m.v to XX Suprarenal Extract, dose, gr. v (by mouth) Caffein Source : Coffee berries and tea leaves. Action : Cardiac Stimulant, Cerebral Excitant and Diuretic. Stimulates intestinal tract slightly. Stimulates heart and nerves directly. Increases thought action and acute sensations. Diminishes fatigue. Stimulates kidney cells. Preparation and Dosage : Caffein Citrate, dose, gr.i to v Caffein Hydrobromate, dose, gr. l to ii Caffein and Sodium Benzoate, dose, gr.ii to x Caffein and Sodium Salicylate, dose, gr.ii to x Symptoms of Overdosage : Caffein in toxic doses produces headache, restless- ness, insomnia, giddiness, profuse urination, colic, rapid, feeble pulse and collapse. Antidote and Treatment : Empty stomach, give Tannic Acid and Aromatic Spirits of Ammonia for stimulation. 28 NURSES HANDBOOK OF Camphor Heart Stimulant, Stomachic and Carminative, Dia- phoretic and Expectorant. Aqua, dose, oz. |- to i Spirits, dose, m.xv to xxx Camphora Monobromata, dose, gr.ii to x I. Heart Stimulants, Continued b. Artery Dilators. Nitroglycerin Source : Made from Glycerin and a mixture of Sul- phuric and Nitric Acid, by washing and evaporation. Action : Cardiac Stimulant, Vasodilator. Reduces blood pressure by dilating arteries and veins. Increases pulse rate. Powerful depressant to motor centers. Flushes skin. Increases res- piration and amount of urine voided. No external or local effect. No direct effect on stomach or heart. Preparation and Dosage : Nitroglycerin, dose, gr. -^\-^ to -^L Spirits of Glonoin (i^ solution in alcohol), dose, m.i to iv Symptoms of Overdosage : Perspiration. Flushed skin. Violent headache. Occasional nausea. Throbbing arteries. Dilated pupils. Intense pain in head. Slow, irregular pulse. DRUGS AND SOLUTIONS 29 Amyl Nitrite Action : Cardiac Stimulant, Vasodilator, Antispas- modic. Quicker effect than Nitroglycerin. Dilates arter- ies immediately. Increases pulse rate. Depresses motor centers. Acts as a heart stimulant. Vapor enters the blood through the lungs with great rapidity and reaches the tissues almost immedi- ately. The muscle walls of the arteries are para- lyzed and the vessels dilate. Blood pressure falls, with consequent relief to the heart, which has less work to do and the same or more strength to do it with. Excreted by the kidneys. Preparation and Dosage : Pearls for inhalation (3 to 5 drops) Symptoms of Overdosage : Fullness and throbbing of vessels. Flushing. Dilated pupils. Deep, labored respiration. Anxiety and restlessness. More severe symptoms are grave depression, with cold extremities. Slow, almost imperceptible pulse. Persistent headache. Pos- sible convulsions and paralysis of heart and nerve centers. Antidote and Treatment : Artificial respiration, Strychnin and Atropin. Sodium Nitrite, dose, gr.ii to v. Slower and more prolonged action than Nitroglycerin. Sweet Spirits of Nitre (Spiritus ^Etheris Nitrosi), dose, dr. 1 to ii. Stimulant, with mild diuretic, diaphoretic, antipyretic and sedative powers. 30 NURSES HANDBOOK OF II. Heart Depressants Aconite Source : Root of European plant called Monks- hood or Wolfsbane. Chief constituent "Aconitin," the most powerful alkaloid known (gr. gV fa-tal), dose, gr. ^1^. Action : Cardiac and Respiratory Sedative, Anti- pyretic, Diuretic. Dilates arteries and decreases pressure in febrile conditions. Externally and locally slightly ab- sorbed. Parasiticide. Analgesic. Paralyzes nerves locally, causing tingling and numbness. Irritant to stomach and causes vomiting. Powerful cardiac poison. Reduces frequency, force and tension. Produces a gentle perspiration and increases flow of urine. Respirations become slower and deeper and temperature falls. Preparation and Dosage : Fluid Extract, m.i to ii Tincture, m.i to iv (old 35^ solution) Tincture, m.i to xv (new 10^ solution) Symptoms of Overdosage : Tingling in mouth and skin. Constricted feeling, in throat. Tongue and breath are cold. Disorders of vision. Staring eyes. Respiration diniinished, and pulse may fall to 30 or 40 a minute. Great muscular weakness. Irregular pulse. Suppressed voice. Mind usually clear, except in cases of con- DRUGS AND SOLUTIONS 3 1 vulsions. Death may occur from paralysis of heart muscles or respiratory center. Antidote and Treatment : Emetics and lavage. Alcoholic stimulants. Ex- ternal heat. Absolute quiet and rest and artificial respiration. Head low. Cardiac stimulants. Atro- pin and Ammonia. Precautions : Pulse, respiration and temperature to be carefully watched. Guard against cold air and drafts. Allow no exertion on the part of patient. Veratrum Viride Source : The roots of Hellebore, an American and European plant. Action : General Depressant. Cardiac Depressant and Spinal Paralyzant. Re- duces pulse in strength and frequency ; lowering the pulse to 35 or 40. Exertion may make it rapid, thready, small and weak from being moderately full and soft. Direct influence on heart muscles, causing a depressing action and muscular weakness. Brain not affected.. Used in Eclampsia, though lacking power over excretion. Affects respirations less than Aconite ; paralyzes motor system cen- trally ; unaffecting sensation, but impairing reflexes. Emetic and Cathartic. Preparation and Dosage : Fluid Extract, dose, m.i to iii Tincture, dose, m.x to xxx (10^) Norwood's Tincture, dose, m.v, increasing (44^) 32 NURSES HANDBOOK OF Symptoms of Overdosage : Nausea and vomiting. Cold, clammy skin and threadlike pulse. Rarely fatal results, though symptoms are alarming, including faintness, loss of sight and partial loss of consciousness. Antidote and Treatment : Emetics and lavage. No exertion. Elevation of feet. Perfect rest. Alcoholic stimulants. Exter- nal heat. Pulse should not be allowed to fall below 70. Many incidental effects : dizziness, choking, dry- ness of mouth, etc. Colchicum Meadow Saffron (roots or seed). Action : Cardio-Respiratory Depressant and Irritant. Emetic, diuretic and diaphoretic, drastic purgative, gastrointestinal irritant and cardiac depressant. Sedative to central nervous system. Used in gout. Pulse slightly reduced in frequency. Stimulates the liver. Preparation and Dosage : Wine of Colchicum Seed, dose, m.xv to xxx Wine of Colchicum Root, dose, m.v to xx Fluid Extract of Colchicum Seed, dose, m.iii to x Fluid Extract of Colchicum Root, dose, m.ii to viii III. Narcotics a. Hydrocarbon Narcotics. Alcohol (Narcotic in large doses) DRUGS AND SOLUTIONS 33 Source : Made by a process of fermentation from substances containing grape sugar, also by chemical process and distillation. Action : Cerebrospinal Excitant, Cardiac and Gas- tric Stimulant, Antipyretic. Externally and locally a fat solvent, cleans the skin, hardens it and slightly stimulates. Irritant and local anesthetic. Relieves pain and has cooling effect (due to evaporation). Antiseptic. Deadens nerve terminals. In the mouth an irritant ; biting and semi-antiseptic. In the stomach an irritant, increasing the secretions ; hence, in small doses, increasing digestion and absorption. Slightly de- pressant to heart. Increases force and frequency of pulse ; causes sweating and heat loss. Marked effect on nervous system ; deadens control of mind and moral sense ; dulls the intellect and muscular control. Four stages: i. Excitement. 2. De- pression. 3. Paralysis. 4. Recovery. It is ex- creted by the lungs and kidneys. Alcohol in fevers reduces temperature by increasing perspiration. Dose, oz. J. Alcoholic Preparations and Beverages Absolute Alcohol contains i^ water. Brandy (Spiritus Vini Gallici) is obtained from grape wine and contains about 45^ alcohol. Whisky (Spiritus Frumenti) is obtained from certain 34 NURSES HANDBOOK OF grains, as rye, corn and wheat, by distillation and contains about 45^ alcohol. Rum is obtained by the distillation of molasses and contains about 42^ alcohol. Gin is grain spirits distilled with Juniper berries and contains about 45^ alcohol. Red Wine (Vinura Rubrum) is obtained from the entire grape and contains y—izfo alcohol. Exam- ples : Claret, Bordeaux and Port. White Wine (Vinum Album) is obtained from the juice of grapes and contains 7-12^ alcohol. Ex- amples : Sherry, Madeira and Catawba. Champagne is a carbonated wine and contains 10-13^ alcohol. Ale or Stout is obtained from barley and hops and contains 5-9^ alcohol. Beer or Porter is also obtained from barley and hops and contains 2-5^ alcohol. Kumyss, a fermented milk preparation, contains 1-3^ alcohol. Ether Source : A highly volatile liquid obtained by the action of strong sulphuric acid upon ordinary alco- hol. Very inflammable. Action : Anesthetic, Cardiac and Respiratory Stimulant. Locally anesthetic and a fat solvent. Is irritating in mouth and stomach. Stimulates heart and cir- DRUGS AND SOLUTIONS 35 culation, also secretions. Stimulates quickly . by hypodermic or mouth. Stimulates the heart by irritating. Is absorbed faster than alcohol, hence the four stages are quicker. Irritates nose, larynx and trachea, increasing secretions. Benumbs the nervous system. Chief vise is for surgical, anes- thesia. Four stages : i . Excitement and stimula- tion. 2. Narcosis. 3. Insensibility. 4. Recovery. Excreted by the kidneys and lungs. Recovery from Surgical Anesthesia : Natural reaction, with poor circulation and possible chills, makes it necessary to keep the patient warm and out of drafts. The excretion of the ether by the lungs requires plenty of fresh air. Increased secretions from the throat and mouth must be sponged out. To prevent the inhalation of vom- itus with the possible nausea, the head must be kept low and to one side. Patient must be watched for surgical shock and collapse. Nitrous Ether. Mild Diaphoretic and Diuretic. Car- minative and Stimulant, dose, m.x to dr.ii Hoffman's Anodyne (Compound Spirit of Ether). Same action, dose, m.x to dr.ii Chloroform Source : A volatile liquid formed by the action of chlorinated lime on methyl alcohol. Action : In addition to the effects of ether, chloro- form has a distinct depressing action on the heart and nervous system. There is danger of complete 36 NURSES HANDBOOK OF cardiac failure. It is less irritating to the kidneys and to air passages, non-inflammable, more agree- able, more prompt in action and produces less vomiting than ether, but is much more dangerous and has more serious after effects. Chloroform is also used locally in liniments as a rubefacient and anodyne and to relieve itching. III. Narcotics, Continued b. The Opium Group. Opium. (Morphin, Laudanum, Paregoric, Codein and Heroin.) Source : The juice of the unripe Poppy seed. Action : Analgesic, Hypnotic, Myotic, Secretory Depressant and in medicinal doses a Cardiac Stim- ulant. Externally and locally, slightly benumbing. Bitter taste and narcotic odor. Decreases appetite and digestion slightly. Causes nausea and vomiting. Constipating effect upon the intestines. Paralyzes peristalsis. Slight effect on circulation. Dilates vessels of skin and increases perspiration. Slight effect upon lungs, except through nervous system. The respiratory tract in the medulla is blunted, 'and respirations become deep and infrequent, and are liable to be destroyed entirely. Moral and intel- lectual senses are blunted, also sensory centers, especially for unpleasant impressions. Slows and steadies heart under certain conditions. Excreted through intestines. Will ' affect a nursing child through the mother's milk. DRUGS AND SOLUTIONS 3/ Preparation and Dosage : Opium, dose, gr. ^ to ii Laudanum (Tincture of Opium), dose, m.v to xv (lO^ Opium, m.x equals gr.i Opium, or gr. ^ Morphin) Paregoric (Camphorated Tincture of Opium), dose, dr.i to oz. i (oz. i equals gr.i) Majendi's Solution of Morphin, dose, m.v to x (m.xxx equals gr.i of Morphin) Morphin Sulphate, dose, gr. J^ to ^ Codein Sulphate, dose, gr. ^ to ii Heroin, dose, gr. -^^ to jL Dover's Powder contains gr.i Opium, gr.i Ipecac, and gr. viii Sugar of Milk Tincture of Deodorized Opium (lofo), (m.x = gr.i), dose, m.v to m.xxv Symptoms of Overdosage : Morphin, gr. ^, and Opium, gr.iii, may produce death. Contracted pupils, drowsiness, deepening stupor, no response to external stimuli, skin moist and clammy, becoming cyanotic. Respirations slow, rate 4 to 6 per minute. Feeble pulse. Coma, pin- point pupils. Death from failure of respirations in 4 to 12 hours. Treatment : Evacuate stomach by tube, if possible. Emetics. Destroy, or neutralize, the poison with Pot. Per- manganate or Tannic Acid (with Morphin, the latter forms Morphin Tannate, which is insolu- ble). Keep awake. Tone respiratory centers with Strychnin, Caffein and Atropin, 38 NURSES HANDBOOK OF Apomorphin (a derivative of Morphin) Dose, gr. J^ (hypo) Emetic Dose, gr. -^-^ Expectorant III. Narcotics, Continued c. Hypnotics. Chloral Hydrate Source : A chemical preparation formed by the action of Chlorine on Alcohol. Action : Powerful Hypnotic, Antispasmodic and Nervous Depressant. Irritates mouth and stom- ach. (Should therefore be "well diluted.) De- presses heart and circulation. Benumbs nervous system, causing sleep. Sometimes causes head- ache, excitement and even delirium. Danger of sudden collapse of heart. Dose, gr.v to xx. Symptoms of Overdosage : Profound sleep. Coma. Slow, feeble, irregular pulse. Slow, shallow respiration. Cold skin. Cyanosis. Antidotes and Treatment : Emetic and lavage. Coffee enemata. External heat. Possibly artificial respiration. Cardiac stimulants. Chloralamid. Hypnotic without after effects. Dose, gr. x to xxx. Amylene Hydrate. More agreeable and safer than Chloral or Paraldehyd. No influence on DRUGS AND SOLUTIONS 39 heart or respiration. No unpleasant after effects. Dose, dr. ^ to iss. Hedonal. Feeble Hypnotic. Considered safer than most other agents of the class. No unpleas- ant after effects. Dose, gr. xv to xxx. Paraldehyd. Hypnotic and Diuretic, with little depression. Readily absorbed by rectum. Safer than Chloral, strengthening and slowing heart's action. Sound, refreshing sleep follows a prelimi- nary stage of excitement. Dose, dr. 1 to ii. Sulphonal. Hypnotic of slow absorption, with un- fortunate after effects. Should be given in hot solutions. Dose, gr.x to xxx. Trional. More soluble than Sulphonal. Should be given in hot milk for best results. Especially effective with Codein. Dose, gr. x to xxx. Veronal. Same action as Trional, only more rapid. Produces a practically normal sleep, and is free from after effects. Dose, gr.viii to x. IV. Respiratory Stimulants Atropin : An alkaloid of Belladonna Source : The Belladonna plant, or Deadly Night- shade. Action : Analgesic, Antispasmodic, Cardiac and Res- piratory Stimulant, Cerebral Excitant, Secretory Depressant, Mydriatic. In small doses a vasocon- strictor, in large doses vasodilator. Most important 40 NURSES HANDBOOK OF actions: i. Respiratory stimulant. 2. To relieve spasms of involuntary muscles, as from stones in gall- bladder, cathartic gripes, etc. 3. To dry secretions of stomach, nose, sweat glands, etc. Externally and locally freely absorbed, with benumbing effects. (Belladonna plaster, ointment and liniment.) Bit- ter taste ; dries the secretions of stomach. Checks excessive spasms of stomach and intestines. Stim- ulates nervous system and brain, sometimes caus- ing delirium. Dries the secretion of all secret- ing glands. Stimulates .and tones whole system. Peculiar effect on the brain, causing excitability and possibly narcosis. Causes dryness of throat. Is a cardiac stimulant. Eliminated by the kidneys. Locally benumbs pain. Dilates pupils by paralysis of constrictor fibers. Preparation and Dosage : Tincture of Belladonna, dose, m.v to x Fluid Extract of Belladonna, dose, m.i to ii Atropin, dose, gr. j^-^ to -^^ Extract of Belladonna, dose, gr. ^ to J Symptoms of Overdosage : Rash. Pupils bright and staring. Dry, flushed skin. Dry throat, with difficulty in swallowing. Headaches, illusions and delirium. Rapid pulse, out of proportion to respirations. Symptoms like those of Scarlet Fever, except for the dilated pupils. Antidotes and Treatment : Evacuate stomach and treat symptoms. Catheter- ize. Apply external heat. Artificial respiration. DRUGS AND SULUTIONS 4I Give Tannic Acid. Pilocarpin, Morphin and Eserin. Stramonium Source : The Jamestown Weed or Thorn Apple. Action : Antispasmodic and Anodyne. Action similar to that of Belladonna. Causes cardiac irregularity and delirium. Relaxes muscles of bronchial tubes more powerfully than Belladonna. Contains the alkaloids, Atropin and Hyoscyamin, also some Hyoscin. The smoke inhaled brings Atropin into contact with the bronchial mucous membrane. Relaxes spasms in Asthma. Leaves prepared in the form of cigarettes. Fluid Extract, dose, m.i to v Tincture, dose, m.v to xv Hyoscyamus Source : Henbane. Action : Same physiological action as Belladonna. Cardiac and Respiratory Stimulant. Greater Seda- tive and Hypnotic (due to Hyoscin). Dries the mouth. Flushes face. Dilates pupils and causes delirium. Used as a sedative in bladder troubles. Preparation and Dosage : Fluid Extract, dose, m.i to v Tincture, dose, m.v to xxx Hyoscin Source : The alkaloid obtained from Hyoscyamus. The active principles have the same chemical for. mula as Atropin, yet are not identical. 42 NURSES HANDBOOK OF Action : Powerful Hypnotic and Spinal and Cere- bral Sedative. Reduces pulse rate and depresses circulation after first stimulating them. Is deadly and very de- pressing. Used in insanities, delirium and mania. Preparation and Dosage : Hyoscin Hydrobromid, dose, gr. yj^ to -^1^- V. Motor and Respiratory Depressants Eserin. An alkaloid from Physostigma. Source : A West African plant (the Calabar Bean). Action : Depresses spinal motor centers and res- piratory centers of the medulla. Stimulates secre- tions, excites nausea, salivation and diaphoresis. Stimulates muscle fibers, especially, those of the intestines, stomach and bronchial tubes. Raises blood pressure. Death may occur from paralysis of respiratory centers. Used in constipation, due to torpor of the bowels, and in Tetanus and Strych- nin poisoning to diminish reflex excitability. A myotic used in eye troubles. Prevents suppuration after operations. Empties vessels of eye and con- tracts pupil, Preparation and Dosage : Eserin Salicylate, dose, gr. -j^^ to -^ Eserin Sulphate, dose, gr. -j^^ to ^1^ Extract of Physostigma, dose, gr. J^ to J Tincture of Physostigma, dose, m.v to xx DRUGS AND SOLUTIONS 43 Symptoms and Treatment of Overdosage : Muscular weakness, tremor, small pupils, slow pulse and respiration. Emetics. Tannic Acid, Atropin, stimulants and artificial respiration. Bromids. Average dose, usually gr.x to xv. Source : Bromin, a non-metallic element found in sea water and in the product of certain salt works. Action : Powerful Depressants to nervous system and circulation. Hypnotic and sedative. VI. The Coal-Tar Products f a. Antipyretics ( b. Antiseptics Source : Prepared by complicated chemical proc- esses from the tar which is formed in the manu- facture of illuminating gas from coal. Action : Externally and locally all are antiseptics and irritants. To the stomach they are irritants- Upon the pain centers of the nervous system they have a blunting influence. a. Antipyretics. Circulation is at first stimulated, later depressed. Vessels of skin are dilated, and there is sweating and heat loss. Transitory stimu- lation of heart, followed by depression. Acetanilid, dose, gr.i to iv. (Death has occurred from gr.v.) Antipyretic and Analgesic and a Cardiac Depress- ant. (Acetanilid is the chief constituent of many "headache powders," making them very dangerous.) 44 NURSES HANDBOOK OF Ammonol, dose, gr.v to x. A proprietary Analgesic and Antipyretic, with stim- ulant and expectorant qualities. Antikamnia, dose, gr.v to xv. A proprietary Antipyretic and Analgesic, said to contain Acetanilid, Sodium Bicarbonate and Caffein. Antipyrin, dose, gr.i to x. Powerful Antipyretic and general Analgesic. Some- what hypnotic, diaphoretic and antiseptic. Migranin, dose, gr.v to xv. A combination of Antipyrin and Caffein. Power- ful Analgesic, used chiefly for sick headache and neuralgia. Dangerously depressant. Aspirin, dose, gr.v to xv t. i. d. A salicylic product. More efficient than the sali- cylates and less irritating to the stomach. Phenacetin (Acetphenetidin), dose, gr.v to x. Antipyretic, Hypnotic and Analgesic. Acts more gradually than the other antipyretics. One of the safest and most efficient of the group. VI. The Coal-Tar Products, Continued b. Antiseptics Have, in general, the same effect as antipyretics, only do not reduce temperature and are more poisonous. Benzoin Antiseptic, Analgesic, somewhat Antipyretic, Dia- phoretic, Diuretic and Stimulating Expectorant. DRUGS AND SOLUTIONS 45 Creosote Antiseptic, Expectorant and Astringent. Used es- pecially for its antiseptic action on pneumococci and tubercle bacilli. Combined with an insoluble salt (Creosote Carbonate, gr.xv) it is less irritating to the stomach. Guiacol, dose, m.v to xv. Chief constituent of Creosote. Antiseptic in tuber- culosis. Powerful local anesthetic, and rapid anti- pyretic when applied externally. Carbolic Acid (Phenol) Antiseptic and Disinfectant. Local anesthetic, also a cardiac respiratory and nervous depressant. Pow- erful irritant and caustic. Readily absorbed, and when poisoning is due to absorption an early symp- tom is a smoky appearance of the urine. Symptoms of Poisoning : Collapse, cold, clammy skin, contracted pupils, feeble, shallow respirations, dark green urine, stupor and coma. Antidote : Externally, Alcohol ; internally. Alcohol and water, equal parts. Picric Acid Externally, Antiseptic, Analgesic and non-irritant to the tissues. Used as local application for burns and Erysipelas. Creolin and Lysol Unofficial Antiseptics and Disinfectants. 46 NURSES HANDBOOK OF Phenol-camphor (Carbolic Acid, i part ; Camphor, 2 parts) Local Anesthetic and Antiseptic. Salicylic Acid Generally prepared from Phenol, but also derived from Salicin or the natural salicylates, Oil of Win- tergreen (Gaultheria) or Sweet Birch. (Methyl- Salicylate or artificial Oil of Wintergreen is a volatile preparation.) Antiseptic, Antipyretic and Germicide. Stimulates and disinfects kidneys and has diaphoretic power. Cholagogue and intestinal antiseptic. Overdosage •produces buzzing and roaring in the ears, disturb- ance of vision, excessive sweating, delirium, cardiac and respiratory depression. Sodium Salicylates (less irritating to the stomach) deaden pain perceptions in rheumatism. Dose, gr.v to XXX. Salol. Intestinal Antiseptic formed by the action of Carbolic Acid on Salicylic Acid. Dose, gr.i to x. VII. Diuretics and Diaphoretics Scoparius (Spartein Sulphate). From the Broom Plant. Diuretic and Laxative, also Emetic, Cathartic and Cardiac Stimulant. Spartein Sulphate, dose, gr. Jg to ii. Fluid Extract of Scoparius, dose, m.x to dr.i. DRUGS AND SOLUTIONS 47 Squill (Scilla) Powerful Diuretic and Expectorant. Gastrointes- tinal Irritant and Cardiac Stimulant. (Acts like Digitalis.) Fluid Extract of Squill, dose, m.i to v. Tincture of Squill, dose, m.v to xxx. Syrup of Squill, dose, dr. ^ to i. Pilocarpin (Jaborandi) Stimulates all the secretions but the bile. Depresses the heart. Dose, gr. ^ to ^. Hydrochlorid. Apocynum (Canadian Hemp) Diuretic, Emetic and Alterative. Fluid Extract, dose, m.ii to mc. Senega. Diuretic and Diaph^Bretic and Stimulating Expectorant. ',' Fluid Extract, dose, m.x to xxx. Syrup, dose, dr.i to ii. Potassium Acetate, dose, gr.xxx. Potassium Citrate, dose, gr.xxx. Rochelle Salt (Potassium and Sodium Tartrate), dose, dr.i to ii. Seidlitz Powder (Compound Effervescing Powder) A. B. C. Diuretic (Potassium Acetate, Bicarbonate and Citrate), dose, oz. ^. Diuretin, dose, gr.x to xv 48 NURSES HANDBOOK OF VIII. Cathartics a. Laxatives (hasten intestinal evacuation). (Ape- rients.) Olive Oil. Castor Oil (Oleum Ricini), dose, oz. \. Glycerin, dose, dr.i to ii. Magnesia. Figs, Prunes and stewed fruit. b. Simple Purgatives (produce active peristalsis and griping pain). Aloes (Aloes, Belladonna and Strychnin Pills). Castor Oil. Rhubarb (Mixture of Rhubarb and Soda, dose, dr.i to iv). Licorice Powder (Compound, dose, dr.i to ii). Cascara (Fid. Ext., dose, m.x to xxx). Senna (Fid. Ext, dose, m.x to dr.i). c. Drastic Purgatives (produce intense action, watery stools and much pain). Croton Oil, dose, m.i to iii (Oleum Tiglii). Jalap (Compound, dose, gr.x to xxx). Aloes. C. C. Pills (Compound Cathartic) Podophyllum (Fid. Ext., dose, m.i to xx). d. Cholagogue Purgatives (remove bile from the intestines). Calomel (Mild Mercurous Chlorid, dose, gr.i to iii). Blue Mass, dose, gr.iv. Gray powder. Podophyllum. Elaterin, dose, gr. ^V to ^^. DRUGS AND SOLUTIONS 49 e. Saline Purgatives (produce slight pain and watery evacuations.) Salts of Magnesia. Salts of Sodium. Salts of Potassium. Saline Waters. IX. Alteratives Arsenic Source : A metal that occurs in combination with many minerals. Action : Tonic, Antiseptic, Antiperiodic and Hema- tinic. Internally a stomachic and general tonic. Increases cardiac action and respiratory power and intestinal secretions. Stimulates peristalsis and exalts mental activity. A tolerance to large doses can be acquired. Used also in depilatories. Pro- duces a fair skin. Quickly absorbed. Eliminated by skin and kidneys chiefly. Often used in neu- ralgia, chronic malaria, anemia, rheumatism and chorea. Increases number of red blood corpuscles. Preparation and Dosage : Fowler's Solution (Sol. of Potassium Arsenite, a ifi sol.), dose, m.ii to vi t. i. d. Arsenous Trioxid (White Arsenic), most frequently used as a poison. Tasteless, cheap and easily procured. Symptoms of Overdosage : Itching and edema of eyelids, nausea and diarrhea. Skin eruptions, irritable heart, dyspnoea. In large 50 NURSES HANDBOOK OF doses a powerful irritant to gastrointestinal and broncho-mucous membranes. Pain in throat and abdomen. Bloody stools. Collapse. (Symptoms resembling those of Cholera.) Treatment : Lavage and emetics. Mucilaginous or albuminous drinks. Raw eggs in milk and lime water. Equal parts oil and lime water. Castor Oil. Opium and stimulants. Counteract depression. Iron (Ferrum) General Tonic and Stomachic. Enriches blood cor- puscles with hemoglobin. Promotes appetite and digestion. Astringent and hemostatic (on account of its power to coagulate albumin). Preparation and Dosage : Tincture of Ferric Chloride, dose, m.v to xv. Basham's Mixture (Sol. of Iron and Ammonium Acetate), dose, dr.ii to vi. Triple Phosphates (Iron, Quinin and Strychnin), dose, dr.i. Syrup of Ferrous lodid, dose, m.v to xl. Blaud's Pills. lodin (I) A non-metallic element found in seaweeds, some fresh-water plants, also in sponge, oysters, eggs, rock salt and several ores. Tonic and alterative, increases elimination and body-weight. Improves general condition. May cause coryza and gastro- intestinal irritation. Used in specific diseases. DRUGS AND SOLUTIONS 51 Potassium lodid, dose, gr.v to xx. Counteracts pathological conditions, promotes ab- sorption of morbid conditions and the elimination of several metallic poisons. Iodoform. Antiseptic, Anesthetic and Alterative agent. Aristol (Thymol lodid). A substitute for Iodo- form. Hydriodic Acid. A substitute for the lodids. Alterative in action. Dose, m.v to xv (dilute). Calcium Chlorid, dose, gr.iii to x. Marked alterative. Increases amount of urine and promotes the excretion of urea. Increases coagu- lability of blood. Urotropin (from Formaldehyd) Urinary and Intestinal Antiseptic. Promotes ex- cretion of uric acid. Efficient as alterative and diuretic in cystitis. Decomposes in the organism, setting free Formaldehyd. Sodium Phosphate, dose, gr.xx to dr.ii. Alterative. Increases secretions, especially bile. Cholagogue. Promotes the nutrition of bony and nervous tissue. X. Metals. (Symbols and Latin names in paren- theses.) Alum (Aluminum, Al). Astringent, Emetic and Antiseptic. Dried Alum, Aluminum Sulphate (Aluminum Ace- tate Sol). 52 NURSES HANDBOOK OF Antimony (Antimonium, Sb). Irritant and Emetic. Tartar Emetic (Antimony and Potassium Tartrate), dose, gr. J^ to ii. Arsenic (Arsenum, As). Tonic and Stomachic and Alterative. Arsenous Acid, Fowler's Solution. Bismuth (Bismuthum, B). Astringent and Sedative. Bismuth Subnitrate, Bismuth Subgallate, etc., dose, gr.v to XX. Cerium (Ce). Gastric Sedative. Cerium Oxalate, dose, gr.i to viii. Copper (Cuprum, Cu). Caustic, Stimulant and Astringent. ' Copper Sulphate (Bluestone), dose, gr.vi to xii (Emetic). Gold (Aurum, Au). Tonic and Alterative. Gold Chlorid, etc. Iron (Ferrum, Fe). Tonic, Stomachic, Astringent, Hemostatic and Hematinic. Basham's Mixture, Blaud's Pills, Syrup of Ferrous lodid, etc. Lead (Plumbum, PI). Astringent, Sedative, Hemostatic. Lead Acetate, dose, gr.ii to v, Lead and Opium Solution. DRUGS AND SOLUTIONS 53 Manganese (Manganum, Mn). Irritant, Caustic, Antiseptic, Disinfectant and Deodorant. Potassium Permanganate. Mercury (Hydrargyrum, H), Quicksilver. Antiseptic and Disinfectant, Astringent, Purgative and Alterative. Specific for Syphilis. Bichlorid of Mercury (Corrosive Sublimate), fatal dose, gr.iii to v. Calomel, Blue Mass, Blue Ointment, Yellow Oxid of Mercury. Silver (Argentum, Ag). Caustic, Astringent, Antispasmodic, Nerve Stimu- lant. Silver Nitrate. Zinc (Zincum, Zn). Caustic, Astringent and Emetic. Zinc Oxid, Zinc Ointment, Zinc Sulphate, dose, gr.xv to XX (Emetic). XI. Intestinal Antiseptics Salol, dose, gr.i to x. Sodium Salicylates, dose, gr.v to xxx. Creosote Carbonate, dose, m.v to dr.i. Urotropin, dose, gr.v. to vii. XII. Intestinal Astringents Bismuth Subnitrate, dose, gr.v to xx. Bismuth Subgallate, dose, gr.v to xx. Powdered Opium, dose, gr. ^ to ii. Preparations of Iron. 54 NURSES HANDBOOK OF Tannic Acid, dose, gr.i to v. Silver Nitrate. Alum, dose, gr.v to xxx. XIII. Antispasmodics Asafetida A powerful Antispasmodic, Nerve Stimulant and Expectorant. Also tonic, laxative, diuretic and diaphoretic. Nauseous in taste and odor. Used in hysterias, flatulent indigestion and bronchial affections. Tincture of Asafetida, dose, m.x to xxx. Emulsion of Asafetida, dose, dr.ii to iv. Valerian Antispasmodic and gentle stimulant to nervous and circulatory systems. Laxative and diaphoretic. Used in hysterias, for nervous coughs, etc. Tincture of Valerian, dose, dr.i. Fluid Extract of Valerian, dose, m'.xxx. Belladonna Opium Chloral Stramonium, etc. XIV. Acids Acetic. Astringent, Hemostatic, Caustic, Diuretic and Antiseptic. Glacial Acetic. Strongly caustic and only used locally. Dilute Acetic {6f>), dose, m.xv to dr.ii. Vinegar (Acetum) is an impure dilute acetic acid. DRUGS AND SOLUTIONS 55 Hydrochloric (Muriatic Acid) Caustic and Stomachic. Checks fermentation. Dilute Hydrochloric, dose, m.iii to xx. (lo^) Hydrocyanic (Prussic Acid) One of the most powerful and rapid poisons known. Death has resulted from smelling it. Dilute Hydrocyanic is used for its antispasmodic and sedative effects. Contains if) of absolute Hydrocyanic Acid and is the only official form. Dose, m.i to ii. Nitric. Caustic and Cholagogue Nitrohydrochloric Acid. Efficient Cholagogue. Dose, m.i to viii. Sulphuric. Astringent, Hemostatic and Caustic. Dilute Sulphuric, dose, m.v to xx. Tannic. Powerful Astringent, dose, gr.i to xx. ANTIDOTES AND TREATMENT FOR POISONING BY Acetanilid. Symptoms : Collapse, cyanosis, slow res- piration, feeble, irregular pulse, vomiting, profuse sweating. Treatment : Belladonna or Atropin, Strychnin, oxy- gen inhalations, heat. Acid, Acetic. Symptoms : Gastrointestinal irritation and collapse. Treatment : Magnesia, soap and water, lime water, chalk, milk, oils and thick gruel. 56 NURSES HANDBOOK OF Acid, Carbolic. Symptoms : Collapse. Cold, clammy- skin. Burning from mouth to stomach. Smoky or dark green urine. Slow respirations. Treatment : Lavage with Alcohol and water, equal parts. Epsom Salts, soap suds, heat to extremities with friction, Atropin and alcoholic stimulants. Lavage with Pot. Permanganate, gr. i| to i pt., or Condy's Fluid, dr.ii to i pt. Acid, Hydrocyanic (Prussic). Symptoms: Coma, dilated pupils, cold, clammy skin, slow, convulsive respira- tions, small, feeble pulse. Death from respiratory failure in a few seconds after large dose. Treatment : Emetics or lavage, artificial respiration with Ammonia inhalations, Atropin, Brandy, Ether. Acid, Oxalic. Symptoms : Gastrointestinal irritation, convulsions, collapse. Death from paralysis of respirations. Treatment : Lime water, chalk, whiting, wall-plaster in water. Magnesia, mucilaginous drinks. Acids, Mineral (Hydrochloric, Nitric, Sulphuric, etc.) Symptoms : Gastrointestinal irritation and collapse, pain. Treatment : Alkalies, as Magnesia, chalk, soap, whiting, wall-plaster in water, albumen, flour, milk, starch, olive oil. Avoid water in Sulphuric Acid cases. Opium, Alcohol and other cardiac stimulants. Aconite, see page 3 1 . Alcohol. Treatment : Emetics or lavage, cold affusion to the head, warmth to extremities, artificial res- piration, Caffein, Chloral and Pot. Bromid. DRUGS AND SOLUTIONS 57 Alkalies. Symptoms : Corrosion, gastrointestinal irri- tation. Treatment : Diluted vegetable acids, as vinegar, lemon juice, etc. Milk, gelatin, oils, Caffein, Alcohol and other stimulants. Ammonia, see Alkalies. Amyl Nitrite, see page 29. Anesthetics (Ether, Chloroform, etc.) Treatment : Oxygen, artificial respiration, Atropin, Strychnin, Adrenalin, heat to the body and limbs. Invert patient, draw the tongue well forward, com- press and relax chest. Arsenic, see page 50. Atropin and Belladonna, see page 40. Chloral, see page 38. Cocain. Symptoms of acute poisoning : Pallor, faint- ing, cardiac and respiratory depression. Treatment : Cardiac stimulants, artificial stimulation. Mercury (Bichlorid, etc., Corrosive Sublimate). Acute symptoms : Gastrointestinal irritation with great pain, vomiting and diarrhea, collapse. Treatment: Egg albumen (i egg for each 4 grains of the poison), demulcents, milk. Later, saline diuretics and rectal irrigation. Opium (Morphin, Laudanum, Paregoric, etc.), see page 37. Phenacetin, see Acetanilid. Digitalis, see page 26. 58 NURSES HANDBOOK OF Formaldehyd. Ammonia is the antidote forming Urotropin. Fish Poison (ptomaine). Emetics and cathartics. Po- tassium Chlorate, Opium, etc. Illuminating Gas. Treatment : Oxygen, artificial res- piration. Ammonia vapor, black coffee enema, hori- zontal position with clothing removed, catheteriza- tion, external heat, cold acid drinks. lodin. Symptoms : Gastrointestinal irritant, colored vomitus. Treatment : Starch water with lavage, flour, gelatin, albumen. Lead. Acute symptoms : Vomiting and colic, collapse. Treatment : Emetics, lavage. Magnesium Sulphate, external heat and cardiac stimulants. Nitroglycerin, see Amyl Nitrite. Phosphorus. Acute symptoms : Vomiting and abdom- inal pain, collapse. Treatment : Emetics and lavage (Potassium Per- manganate I : 6000), saline purge. Strychnin and Nux Vomica, see page 25. Veratrum Viride, see page 32. PART IV COMMON FORMULA A. B. C. Diuretic (Mistura Diuretica) A half-an-ounce dose contains Potassium Acetate, gr.viiss Potassium Bicarbonate, gr.viiss Potassium Citrate, gr.viiss Alum Acetate Liquor Aluminum Sulphate, Glacial Acetic Acid, Calcium Carbonate and Distilled Water. Anti-Alcoholic Mixture (Mistura Chloralis Composita) A half-ounce dose contains Chloral, gr.xv Morphin Sulphate, gr. ^ Tr. of Hyoscyamus, m.xxx Ginger and Capsicum Basham's Mixture One drachm contains approximately Tincture Ferric Chlorid, m.iiss Dilute Acetic Acid, m.iiiss Liquor Ammonium Acetate, m.xxx Aromatic Elixir, m.vii Glycerin, m.vii Water, m.x Dose, dr.ii+ S9 60 NURSES HANDBOOK OF Blaud's Pills Iron Sulphate, gr.iiss Potassium Carbonate, gr.iiss Brown Mixture (Compound Glycyrrhiza Mixture) One ounce contains Extract of Licorice, gr.xv Acacia, gr.xv Paregoric, dr.i Wine of Antimony, m.xxx Spts. of Nitrous Ether, m.xv Water and Syrup Dose, dr.i to oz.i Bronchitis Tablets (Delafield) One tablet contains Extract of Belladonna Leaf, gr. -^rf Dover's Powder, gr. ^-^ Pulverized Ipecac, gr. jV Quinin Sulphate, gr. ^ C. C. Pills (Compound Cathartic) One pill contains Extract of Colocynth (Compound), gr. i^ Calomel, gr.i Resin of Jalap, gr. 1 Powdered Gamboge, gr. ^ Citrate of Magnesia One bottle contains Magnesium Carbonate, i6o grains Citric Acid, 320 grains Oil of Lemon, few drops Sugar and Water, 12 ounces DRUGS AND SOLUTIONS 6 1 Chloroform Liniment Chloroform, Laudanum, or Camphor or Almond Oil. Compound Licorice Powder One drachm contains Powdered Sugar, gr.xxx Oil of Fennel, m. J Washed Sulphur, gr.v Powdered Senna, gr.xss Powdered Licorice, gr.xiv Dose, dr.ss to ii Dobell's Solution Sodium Borate (Borax), dr.ii Sodium Bicarbonate, dr.ii Glycerin, dr.iv Carbolic Acid, m.xx Distilled Water, q. s. ad oz.xvi Imperial Drink (Haustus " Cremor Tartari ") Potassium Bitartrate, i6o grains Spirit of Lemons, 1 5 minims Syrup, 3^^ ounces Water, q. s. ad 32 ounces Red Wash Zinc Sulphate, 10 grains Tincture of Lavender, 2 drachms Water, q. s. ad 4 ounces Rhinitis Capsules One capsule contains Extract of Pulverized Belladonna, gr. ^ Quinin Sulphate, gr.ii Camphor, gr.ii 62 NURSES HANDBOOK OF Rhubarb and Soda Mixture One drachm contains Sodium Bicarbonate, gr.ii Fid. Ext. Rhubarb, m.ii (Fid. Ext. Ipecac) Glycerin, m.viii Spirits of Peppermint, m.ii Water, m.xlvi Dose, dr4+ Seidlitz Powders (Compound Effervescing Powder) Sodium Bicarbonate, 45 grains and Potassium-Sodium Tartrate (Rochelle Salt), 117 grains in each blue paper Tartaric Acid, 34 grains in each white paper Stokes' Expectorant One drachm dose contains Ammonium Carbonate, gr.i Fid. Ext. Senega, m.ii Fid. Ext. Squill, m.ii Paregoric, m.xi Syrup of Tolu Water Thiersch's Solution (Liquor Boro-Salicylicus) Salicylic Acid, gr. xv Boric Acid, gr.xc Water, q. s. ad oz.xvi Triple Phosphates (Elixir Ferri, Phosphatis, Quininse et Strychninse) One drachm dose contains about Iron Phosphate, gr.ii DRUGS AND SOLUTIONS 63 Potassium Citrate Quinin Hydrochlorate, gr.i Strychnin Sulphate, gr. j-^ Alcohol Distilled Water Aromatic Elixir Dose, dr.i to ii Warburg's Tincture One drachm contains Purified Aloes, gr.ii Rhubarb, gr. i Angelica Root, gr. i Sweet Flag, gr. J Fennel, gr. J Gentian, gr. ^ Cubeb, gr. | Myrrh, gr. | Elecampane, gr. ^ White Boletus, gr. ^ Curcuma, gr. ^ Camphor, gr. ^ Quinin, gr. i| Alcohol, m.xxxv Water, m.xv LATIN PHRASES AND ABBREVIATIONS aa. ana of each a. c. ante cibum before meals ad ad to, up to ad lib. ad libitum at pleasure 64 NURSES HANDBOOK OF alb. albus white alt. alter the other alt. hor. alternis horis every other hour alt. noc. alterna nocte every other night aq. aqua water aq. calc. aqua calcis lime water aq. dest. aqua destillata distilled water aq. pur. aqua pura pure water b. i. d. bis in die twice a day c. cum with c. c. centimeter cubicum cubic centimeter comp. compositus compound dil. dilutus dilute div. in p. seq. dividatur in partes Let it be divided sequales into equal parts dr. drachma a drachm (60 grains) et et and ext. extractum extract F. Fahrenheit fl. fluidus fluid fol. folia leaves garg. gargarisma a gargle gm. gramma a gramme gr- granum a grain gtt. gutta a drop h. hora hour hor. hora hour infus. infusum an infusion inject. injectio an injection K. Kalium Potassium DRUGS AND SOLUTIONS 65 lac. Lac, lactis milk, of milk lb. libra a pound liq. liquor a solution lot. lotio a lotion M Misce mix m. minimum a minim min. minimum a minim mist. mistura mixture mol. mollis soft nig. niger black no. numero in number noct. nocte at night O. octarius a pint ol. oleum an oil 0. h. omni hora every hour 0. m. omni mane every morning 0. n. omni nocte every night OS OS the mouth OZ. uncia an ounce p. r. n. pro re nata occasionally, as ■ needed p. c. post cibum after meals per per through, by means of per OS by mouth per rectum by rectum pulv. pulvis powder q.h. quaqua hora every hour q. S. quantum sufficit as much as is sufficient R. recipe take 66 NURSES HANDBOOK OF rad. radix root rub. ruber red sem. semen seed S. 0. s. si opus sit if necessary sp. gr. specific gravity s. sine without ss. semissis a half sol. solutio a solution spt. spiritus a spirit Stat. statim immediately s. f. spiritus frumenti whisky s. V. r. spiritus vini recti- ficatus alcohol S. V. g. spiritus vini gallici brandy syr. syrup a syrup t. i. d. ter in die thrice daily tr. tinctura tincture troch. trochiscus a lozenge ung. unguentum an ointment vin. vinum wine PART V ANTITOXINS, VACCINES AND SERA Toxins are specific poisons produced by bacterial growth in suitable media, and when circulating in the organism they are the immediate causes of the acute infectious diseases. Those constantly associated with certain infectious diseases are, notably, Tetanus, Diphtheria, Cholera, Pneimionia, Erysipelas and Typhoid. Antitoxins are supposititious substances believed to be produced by the cells of the blood or tissue for the defense of the organism against foreign bacterial toxins. Antitoxic Sera are composed of blood serum con- taining antitoxin produced therein by the cells of the organism as a result of the repeated injection of a toxin into the tissues of the animal from which the serum is taken. An Antitoxic Unit is generally recognized as the quantity of an antitoxic serum which will counteract a definite amount of toxin in a guinea pig. Bacterial Vaccines are suspensions of killed bacteria in sterile salt solution. Generally speaking vaccines are composed either of the bacteria themselves unchanged, except in so far as they are affected by the heat used in killing them, or by pulverization, or are some deriva- tive of the bacterial cell. (Tuberculin, for instance, is a vaccine of the tubercle bacilli) 67 68 NURSES HANDBOOK OF The treatment of diseases due to pathogenic microbes, by the toxic products, is based upon the theory that these germs produce substances in their culture media which are hostile to their own life. (By culture media is meant substances used for cultivating bacteria.) In 1 89 1 the following law was formulated by Behring : "The blood serum of an animal which has been artificially rendered immune against a certain infectious disease, when injected into the body of another animal, has power to protect the latter individual against the same disease and to cure the disease after infection has occurred." The fact of spontaneous recovery from infectious disease indicates that the body has the power to im- munize itself against the bacteria and the bacterial products which are its cause. This faith in such im- munizing ability is shown in the present method em- ployed in the treatment of pulmonary tuberculosis, of placing the patient under the best conditions of hygiene and trusting for the cure to the inherent power of the body. The only real success in securing protection against, and in the cure of diseases produced by microorganisms, is now known to be based upon the artificial direction of the body's own immunizing ability, by means of re- moving obstacles to its action, of furnishing the appro- priate stimulus when such is lacking, or by the addition to the blood stream of specific substances which the body itself produces, but not in sufficient quantity to be effective in the production of a state of immunity against the infection under which it is struggling. DRUGS AND SOLUTIONS 69 In protection against typhoid, for instance, the use of typhoid vaccine induces the protective mechanism to fortify the blood with elements that are calculated to destroy typhoid bacilli when they enter the body. Quite the same elements appear to be responsible for the recovery from the disease. A good example of success in following nature's lines of treatment in the cure of disease is that obtained in the treatment of diphtheria by antitoxin. Here we furnish, at a time when the body may be lacking in ability to neutralize the toxin of diphtheria, a substance, which is known to neutralize diphtheria poison and render it inert. The remarkable reduction in the mortality in diphtheria attests the efficacy of this measure. Not only has the mortality been reduced, but there has been an extraor- • dinary decrease in the severity of symptoms. The prophylactic or immunizing dose in diphtheria is from 500 to 1000 units. Immunity is freedom from risk of infection. There are two kinds. Active and Passive. Active Immunity may be caused by recovery from a natural attack of an infectious disease, or it may be caused by the use of a vaccine which may be composed of living cultures of pathogenic bacteria of diminished or altered virulence, or of bacteria that have been killed by heat. An example of the use of a living vaccine is Vaccination. For this method is used a culture of the smallpox organism that has been modified by passage through calves (by inoculation). This modification is of such a nature that it has lost its power of producing the general disease, smallpox, but it has retained that ^0 NURSES HANDBOOK OF of causing a local disease, vaccinia, or cowpox, other- wise similar in nature. It appears here that through the stimulus which this mild disease furnishes, the cells of the body have derived an increased power to resist infection of smallpox. Here, then, has been made use of the body's own methods of protection against disease. Another example of the production of active immu- nity by the use of a vaccine is the treatment for Rabies (Hydrophobia). The organism of this disease is un- known, but the virus occurs in the brain, and emulsions of this substance are used for inoculation. Rabbits, are inoculated with this and their infected spinal cords are dried and used as a vaccine. This, in gradually increasing degrees of virulence, is given to patients, ■ depending on the time in which the drying has gone on. (Drying removes the virulence after a time.) Passive Immunity, or Antitoxic Immunity, is con- ferred in experimentation by injecting into a susceptible animal the serum of one which has acquired an active immunity to the disease in question. Active immunity takes some time, but passive immunity is established as soon as the serum has become mixed with the blood of the person or animal injected. Hence in severe infec- tions our best hope is in the production of passive immunity. Passive immunity is of brief duration. In general terms the duration is three to six weeks. All the Antitoxins cause passive immunity. DRUGS AND SOLUTIONS J I USES OF ANTITOXINS, VACCINES AND SERA Antistaphyloccic sera and vaccines have been pre- pared from virulent cultures derived from severe boils and carbuncles, and are sometimes used with benefit. Antistreptoccic sera and vaccines have been of great use in Erysipelas and other infections. In Bacilli Coli infections (Cystitis, etc.) the vaccine treatment has met with remarkable success. For Cholera, vaccines have been used with strikingly good results. The immunity afforded by the preventive inoculations lasts for a year. The value of the method has been proved to the full, particularly in India, where it has been used to a large extent. Diphtheria antitoxin treatment has been demon- strated to be of the greatest value. The sole preventive treatment in actual use consists in the use of compara- tively small doses of antitoxin. The protection which it confers is usually a strong one, but exceptions have been known. It lasts about a month. (See page 69.) In Gonococcic infections vaccine treatment has been of the greatest possible value, and results are usually beneficial in the extreme. In Meningococcic infections serum from convales- cent cases of meningitis is sometimes used, and there have been excellent results in some instances. Vaccines have been used in Pneumococcal Septi- caemia with good results. In acute pneumonia vaccine treatment has been used in a very satisfactory manner, and the general condition of patients has improved. It 72 NURSES HANDBOOK OF has been of especial value in unresolved consolidation, which often clears up after its use. Plague Sera have been prepared and used in the treatment of the disease with very favorable results. It appears that no other treatment available has been so successful. The results from the preventive treat- ment have not been so successful, but of the value of the method there can be no doubt, and statistics prove clearly that the treatment (by a vaccine) lowers the likelihood of infection and also the case-mortality. The treatment of Rabies or Hydrophobia by vac- cines has shown remarkable results. There are several methods, but whatever the method the value of the process cannot be doubted. Active immunization ap- pears necessary, because of the long period of incubation (one week to two months or longer) and the localization of the virus in the nerves. After the bite of a rabid animal the probability of the patient's developing the disease depends upon the severity of the bite, its posi- tion (that is, whether in regions rich in nerves or the reverse), and on whether the bite is through clothing, so that some of the virus is wiped from the teeth. (See page 70.) Results of the experiments in the treatment and prevention of Syphilis by sera or vaccines have been unsuccessful as a rule. Tetanus antitoxin is of great value as a prophylactic agent and it is of some value in chronic tetanus, that is, in the form with mild symptoms developing after a long period of incubation. Dose, 5 to 10 c. c. Concerning a Tubercle antitoxin, nothing really DRUGS AND SOLUTIONS 73 definite is known. The Tuberculin Reaction is chiefly used for rapid diagnosis of tuberculosis, and its main value is that it enables a negative diagnosis to be made with some degree of confidence, and is the only agent that will do so. Tuberculin vaccines are sometimes used for com- bating the disease. Results have been favorable in conferring a certain amount of increased resistance. In Typhoid P"ever a natural attack will confer im- munity, which probably has a duration of several years. Immunity due to preventive inoculation is thought to last six months at least. Curative treatment by serum or vaccines has not been satisfactory. The preventive treatment by the use of vaccines has been shown to confer a real though not absolute protection against an attack, and to be of still more value in diminishing the mortality rate among those attacked. (See page 69.) INDEX Abbreviations, 63-66 A. B. C. Diuretic, 22, 47, 59 A. B. & S. Pills, 48 Acacia Gum, 7 Accumulative Action, Modifying Dosage, 10 Acetanilid, i, 22, 43 Antidote, 55 Acetate, Lead, 18, 52 Potassium, 47 Acetic Acid, 3, 23, 54 Antidote, 55 Acetphenetidin, 44 Acetum (Vinegar), 54 Acids, 2, 4, 6, 23, 54 Acetic, 3, 23, 54 Antidote, 55 Benzoic, 6 Boracic, 20 Boric, 20 Carbolic, 3, 19, 20, 22, 45 Antidote, 56 Hydriodic, 51 Hydrochloric, 23, 55 Antidote, 56 Hydrocyanic, 2, 23, 55 Antidote, 56 Muriatic, 55 Nitric, 23, 55 Antidote, 56 Oxalic, Antidote, 56 Picric, 22, 45 Prussic, 55 Antidote, 56 Salicylic, 22, 46 Sulphuric, 23, 55 Antidote, 56 Tannic, z, 23, 54, 55 Aconite, i, 2, 3, 5, 21, 30 Antidote, 31 Aconitin, 30 Administration, Modifying Dosage, 10 Adrenalin, 2, 6, 21, 26, 27 Alcohol, I, 3,'4, 5, 6, 21, 32, 33 Antidote, 56 Alcoholic Beverages, 33, 34 Ale, 34 Alkalies, Antidote, 57 Alkaline Solutions, 6 Alkaloidal Hypnotics, 22 Alkaloids, 22, 24, 30, 36, 39, 41, etc. Aloes, 3, 48 Alteratives, i, 23, 49 Alum (Aluminum), 2, 4, 6, 18, 23, 51.54 Alum Acetate, 2, 18 Alum Acetate Liquor, 59 Ammonia, Aqua, 4, 6 Antidote, 57 Ammonal, 22, 44 Ammonium Carbonate, 4 Ammonium Chlorid, 4 Amylene Hydrate, 21, 38 Amyl Nitrite, 21, 29 Antidote, 29 Analgesics, i Anesthesia, Surgical, 35 Anesthetics, 1, 3, 5 Antidote, 57 Anodyne, Hoffman's, 21, 35 Anodynes, i, 5 Anti-Alcoholic Mixture, 59 Antidotes, >:, 55-58 Antikamnia, 22, 44 Antimony, 23, 52 Antiperiodics, 2 Antipyretics, 2, 22, 43 Antipyrin, 22, 44 Antiseptics, 2, 18, 19, 20, 22, 23, 43. 44> 53 75 76 INDEX Antispasmodics, 2, 23, 54 Antitoxic Unit, 67 Antitoxins, 67 Aperients, 22, 48 Apocynum, 22, 47 Apomorphin, 4, 38 Apothecaries' Weight, 11 Application of Drugs, 8, 9 Approximate Equivalents, 12 Aqua (Water), 6 Aqua Ammonia, 6 Aristol, 51 • Arsenic, i, 2, 4, 6, 23, 49, 52 Antidote, 50 Arsenous Trioxid, 49 Artery Constrictors, 21, 24 Artery Dilators, 21, 28 Asafetida, 2, 3, 23, 54 Aspirin, 22, 44 Astringents, 2, 23, 27, 53 Atropin, i, 5, 22, 39 Antidote, 40 Bariey, 3 Basham's Mixture, 50, 59 Beer, 34 Belladonna, i, 2, 5, 39, 54 Antidote, 40 Benzoate, Sodium, 27 Benzoic Acid, 6 Benzoin, 4, 22, 44 Beverages, Alcoholic, 21, 33, 34 Bichlorid of Mercury, 3, 19, 53 Antidote, 57 Bile, 3, 48 Bismuth, 2, 23, 52 Subgallate, 23, 53 Subnitrate, 23, 53 Blaud's Pills, 50, 60 Blue Mass, 48, 53 Ointment, 53 Bluestone, 52 Boracic Acid, 20 Boric Acid, 20 Brandy (Spr. Vin. Gall.), 33 Bromids, 2, 3, 5, 22, 43 Bronchitis Tablets, 60 Broom Plant, 46 Brown Mixture, 60 Caffein, 2, 4, 5, 21, 22, 27 Antidote, 27 Calabar Bean, 42 Calcium Chlorid, 23, 51 Calomel, 3, 4, 48, 53 Camphor, 3, 4, 21, 28 Cerate, 6 Camphorated Tincture of Opium, 37 Camphor-Phenol, 22, 46 Canadian Hemp, 47 Cantharides, 5 Capsicum (Pepper), 5, 6 Carbolic Acid, 2, 3, 19, 20, 22, 45 Antidote, 56 Carbonate, Creosote, 53 Cardiac Sedatives, 2, 21, 30 Cardiac Stimulants, 2, 21, 24 Carminatives, 3 Carton OU, 20 Cascara, 48 Castor Oil, 48 Cathartics, 3, 22, 23, 48, 60 C. C. puis, 48, 60 Cerate (Ceratum), 6 Camphor, 6 Cerebral Depressants, 3 Stimulants, 24 Cerium, 23, 52 Champagne, 34 Children, Dosage for, 9 Chloral, i, 2, 3, 5, 21, 38, 54 Antidote, 38 Chloral Hydrate, see Chloral Chloralamid, 21, 38 Chlorid, Calcium, 23, 51 Ferric, 6 Mild Mercurous, 48 of Lime, 3, 18 Chloroform, I, 6, 21, 35 Antidote, 57 Liniment, 61 Cholagogues, 3 Purgative, 23, 48 Cholera, 71 Citrate, Caffein, 27 of Magnesia, 4, 60 Potassium, 47 Classification of Drugs, 21-23 Coal-Tar Products, 2, 22, 43 INDEX 77 Cocain, i, 5 Antidote, 57 Codein, 21, 36 Cod-liver Oil, i, 4, 7 Coffee, 4, 27 Colchicum, i, 21, 32 Comp. Cathartic Pills, 48, 60 Effervescing Powders, 47, 62 Glycyrrhiza Mixture, 60 Licorice Powder, 61 Spirits of Ether, 35 Constrictors, Artery, 21, 24 Eye. S Convallaria, 4 Copper, 23, 52 Corrosive Sublimate, 53, 57 Counter-irritants, 5 Creolin, 2, 3, 22, 45 Creosote, 22, 23, 45 Creosote Carbonate, 53 Croton OU, 48 Cubic Centimeter, 11 Cystitis, 7 1 Deadly Nightshade, 39 Decoction, 6 Definitions, 1-8 Demulcents, 3 Deodorized Opium, 37 Depressants, Cerebral, Heart, 2, 21, 30 Motor, 22, 42 Respiratory, 5, 22, 42 Dessertspoonful, 12 Diaphoretics, 3, 22, 46 Digitalis, 2, 4, 21, 25 Antidote, 26 Dilators, Artery, 21, 28 Pupil of Eye, s Diphtheria, 69, 7 1 Disinfectants, 3 Excreta, 18, 19, 20 Instruments, 19, 20 Linen, 19, 20 Diuretics, 4, 22, 46 Diuretic, A. B. C, 22, 47 Diuretin, 47 Dobell's Solution, 61 Dosage, Estimation of, 16, 17 Modification of, 9, 10 Dover's Powder, 37 Drachm, 11 Drastic Purgatives, 23, 48 Dressings, Antiseptic, 18 Drugs, Application of, 8, 9 Classification of, 21-23 Preparation of, 6-8 Ecbolics, 4 Elaterin, 3, 48 Electricity, 5 Elixir, 6 Ferri, Phosphatis, Quininae et Strychnina;, 62 Emetics, 4 Emetic, Tartar, 4 Emmenagogues, 4 Emulsion, 7 Emulsum Olei Morrhuae, 7 Equivalents, 12 Ergot, 4 Erysipelas, 67, 71 Eserin, 5, 22, 42 Antidote, 43 Ether, i, 3,4, 5,6, 21, 34 Antidote, 35, 57 Comp. Spirits of, 35 Nitrous, 21, 35 Examples of Solution Problems, 14-18 Excitants, 4 Expectorants, 4 Extract, 7 Eye, Contraction of, 5 Dilatation of, 5 Ferric Chlorid, 6 Ferrous lodid, 50 Ferrum (Iron), 50, 52 Fever, Reduction of, 2 Figs, 48 Fire, 3 Fish Poison, Antidote, 58 Flaxseed, 3 Fluid Extract, 7 Formaldehyd, 3, 19 Antidote, 58 Formalin, 19 Formulae, 59-63 Fowler's Solution, 49 78 INDEX Foxglove, 25 Fruit, Stewed, 48 Fumigation, 19 Gargles, 18, 19 Gas, Illuminating, 58 Nitrous Oxid, i Gastric Sedatives, 18 Gastric Tonics, 6 Gelatin, 3 Gin, 34 Ginger, 3, 5 Glacial Acetic Acid, 54 Glassful, 12 Glonoin, Spirits of, 28 Glycerin, 3, 48 Glycerite, 7 Gold (Aurum), 23, 52 Gonorrhoea, 71 Grain, 11, 12 Gramme, 1 1 Gray Powder, 48 Guiacol, 22, 45 Gum Acacia, 7 Habituation, Modifying Dosage, ID Haustus Cremor Tartar!, 61 Heart Depressants, 2, 21, 30 Heart Stimulants, 2, 21, 24 Hedonal, 21, 39 Hellebore, 31 Hematinics, 4 Hemoglobin, 4 Hemostatics, 6, 26, 27 Hemp, Canadian, 47 Henbane, 41 Heroin, 21,36 Hoffman's Anodyne, 21, 35 Homatropin, 5 Honey, 3 Hydrargyrum, 53 Hydriodic Acid, 51 Hydrocarbon Narcotics, 21, 32 Hydrochloric Acid, 23, 55 Antidote, 56 Hydrocyanic Acid, 2, 23, 55 Antidote, 56 Hydrogen Peroxid, z, 19 Hydrophobia, 70, 72 Hyoscin, 5, 22, 41 Hyoscyamus, 22, 41 Hypnotics, 3, 5, 21, 22, 38 Alkaloidal, 22 Idiosyncrasy, Modifying Dosage, 10 Immunity, Modifying Dosage, 10 Imperial Drink, 61 Infusion, 7 Intestinal Antiseptics, 23, 53 Intestinal Astringents, 23, 53 lodid. Ferrous, 50 Potassium, 51 Thymol, 51 locUn, I, 2, s, 23, so Antidote, 58 Iodoform, 51 Ipecac, 4 Iron (Ferrum), 4, 23, 50, 52, 53 Irrigations, 19, 20 Jaborandi, 47 Jalap, Comp., 48 Kilo, II Kilogramme, 11 Kumyss, 34 Lard, 6, 8 Latin Abbreviations, 63-66 Laudanum, 21, 36 Antidote, 37 Laxatives, 22, 48 Lead (Plumbum), 23, 52 Antidote, 58 Acetate, 52 Licorice, 4 Comp. Powder, 48, 61 Lime, 2, 18 Chlorid, 3 Water, 18, 20 Liniment, 7 Belladonna, 7, 40 Chloroform, 61 Lime, 20 Linseed Oil, 20 Liquor (Solution), 7 Boro-Salicylicus, 62 Calcis, 7 INDEX 79 Liter, 12 Local Anesthetic, i Local Anodyne, i Local Sedatives, 7 Lysol, i!, 3, 18, 22, 45 Magnesia, 48 Salts, 49 Magnesium Citrate, 4, 60 Majendi's Sol. of Morphin, 37 Manganese, 23, 53 Meadow Saffron, 32 Measures, j i Meningitis, 71 Menstruation, Restoring, 4 Menthol, 1 Mercury, 23, 53 Antidote, 57 Bichlorid, 3, 19, 53 Metals, 23, 51 Meter, 11 Metric System, 11 Migranin, 22, 44 Minim, 11, 12 Fraction of, 17 Mistura Chloralis Composita, 59 Mistura Diuretica, 59 Mixture (Mistura), 8 Anti-Alcoholic, 59 Brown, 60 Basham's, 50, 59 Comp. Glycyrrhiza, 60 Rhubarb and Soda, 62 Modification of Dosage, 9 Monkshood, 30 Morphin, 21, 22, 36 Antidote, 37 Morrhuae, Oleum, 7 Motor Depressants, 22, 42 Muriatic Acid, 55 Mustard (Sinapis), 3, 4, 5 Mydriatics, 5 Myotics, 5 Naphthol, 2 Narcotics, 3, 5, 21, 32, 36 Nicotin, 5 Nitrate, Silver, 53, 54 Nitre, Sweet Spirits, 21, 29 Nitric Acid, 23, 55 Antidote, 56 Nitrite, Amy), 29 Sodium, 29 Nitroglycerin, 2, 21, 28 Antidote, 29, 57 Nitrous Ether, 21, 35 Nitrous Oxid, I Normal Saline, 13 Norwood's Tincture, 31 Nux Vomica, i, 6, 24, 25 Antidote, 25 Oleum MorrhuEe, 7 , Oleum Ricini, 48 TigUi, 48 Olive Oil, 3, 48 Oil, Carron, 20 Castor, 48 Cod-liver, i, 4, 7 Croton, 48 Linseed, 3 Olive, 48 • of Peppermint, 3 of Rue, 4 Oils, Volatile, i Ointment (Unguentum), 8 Blue, 53 Opium, I, 2, 3, 5, 21, 23, 36, 53, 54 Antidote, 37 Group, 21, 36 Ounce, II Oxalic Acid, Antidote, 56 Oxid, Nitrous, i Zinc, 1 Yellow, 53 Oxytocics, 4 Paraldehyd, 5, 21, 39 Paregoric, 21, 36 Antidote, 37 Pepper (Capsicum), 6 Peppermint, 3 Pepsin, 6 Permanganate, Potassium, z, 3, 18, S3 Peroxid of Hydrogen, 2, 8, 19 Petrolatum, 6 Phenacetin, i, 22, 44 Antidote, 58 8o INDEX Phenol, I, 5, 19, 20, 45 Phenol-Camphor, 22, 46 Phosphorus, I Antidote, 58 Phosphate, Sodium, 23, 51 Physostigma, 42 Picric Acid, 22, 45 Pilocarpin, 2, 3, 5, 22, 47 Pills, A. B. &rS., 48 Blaud's 50, 60 C. C, 48, 60 Pint, II Plague, 72 Plumbum (Lead), 52 Pneumonia, 71 Podophyllum, 3, 48 Poisoning, Antidotes for, 55 Poppy, 36 Porter, 34 Potassium, 2, 4, 6, 49 Acetate, 22, 47 Bicarbonate and Citrate, 47 Arsenate, 49 Citrate, 22, 47 lodid, 2, 51 Permanganate, 2, 3, 18, 53 and Sodium Tartrate, 22, 47 Pound, II Powder, Dover's, 37 Gray, 48 Comp. Licorice, 48, 61 Seidlitz, 22, 47, 62 Preparations of Drugs, 6-8 Problems, Solution, 14-18 Prunes, 48 Prussic Acid, 55 Antidote, 56 Ptomaine Poisoning, 58 Pulsatilla, 4 Purgatives, 3, 22, 23, 48, 49 Quart, II, 12 Quicksilver, 53 Quinin, 2, 4 Rabies, 70, 72 Recovery from Anesthesia, 35 Red Wash, 61 Red Wine, 34 Respiratory Depressants, 5, 22, 42 Respiratory Stimulants, 5, 24, 39 Rhinitis Capsules, 61 Rhubarb, 3, 48 and Soda Mixture, 62 Ricini, Oleum, 48 Risus Sardonicus, 25 Rochelle Salt, 22, 47 Rubefacients, 5 Rule for Children's Dosage, 9 Rules for Solutions, 12, 13, 14, 15 Rum, 34 Salicylates, 2, 3, 23, 46, 53 Salicylic Acid, 22, 46 Saline Purgatives, 23, 49 Saline Solution, 13 Saline Waters, 49 Salol, 22, 23, 46, 53 Salt, 4 Rochelle, 47 Solution, 13 Salts, Magnesia, 49 Potassium, 4, 49 Sodium, 4, 49 Scoparius, 22, 46 Scopolamin, see Hyoscin, Hydro- bromid, 5, 22, 41 Scruple, II Sedatives, 2, 5, 18 Seidlitz Powder, 22, 47, 62 Senega, 22, 47 Senna, 48 Septicaemia, 71 Sera (Serums), 67 Sialogogues, 5 Silver (Argentum), 2, 23, 53, 54 Silver Nitrate, 23 Simple Purgatives, 22, 48 Sleep Producing, 5 Smallpox, 69 Sodium Nitrite, 21, 29 Sodium Phosphate, 23, 51 Sodium Salts, 4, 49 Sodium Salicylates, 46, 53 Solution (Liquor), 7, 18, 19, 20 Problems, 14-18 Dobell's, 61 Fowler's, 49 Majendi's, 37 Saline, 13 INDEX 8i Solution, Table, 13 Thiersch's, 62 Spartein, 46 Spirit (Spiritus), 8 Spirits of Glonoin, 28 Spirits of Nitre, Sweet, 21, 29 Spiritus Frumenti (Whisky), 33 Spiritus Vini Gallici (Brandy), 33 Sprays, 18 Spinal Cord Excitants, 4 Squill, 22, 47 Starch, 3 Stimulants, Cerebral, 24 Heart, 2, 21, 24 Respiratory, 5, 22, 24, 39 Stokes' Expectorant, 62 Stomachics, 6 Stomach Washing, 18 Stout, 34 Stramonium, 2, 22, 41, 54 Strophanthus, 4 Strychnin, i, 2, 4, 5, 21, 22, 24, 25 Antidote, 25 Styptics, 6 Sudorifics, 3 Sulphate, Zinc, 2, 4, 53 Sulphonal, 21, 39 Sulphur, I, 4 Sulphuric Acid, 23, 55 Antidote, 56 Suppository, 8 Suprarenal Extract, 27 Surgical Anesthesia, 35 Sweat, 3 Sweet Spirits of Nitre, 21-29 Syphilis, 72 Table of Equivalents, 12 Tables, Metric System, 11 Troy Weight, 1 1 Wine Measure, 11 Tablespoonful, 12 Tablets, Bronchitis, 60 Tannic Acid, 2, 23, 54, 55 Tartar Emetic, 4 Tartrate, Potassium and Sodium, 22,47 Tea, 4, 6, 27 Teacupful, 12 Teaspoonful, iz Tetanus, 72 Theory of Antitoxins, 68 Thiersch's Solution, 6z Thymol lodid, 51 Tiglii, Oleum, 48 Tincture, 8 Norwood's, 31 Warburg's, 63 Tobacco, 3, 4 Tonics, Gastric, 6 Toxins, 67 Trional, 5, 21, 39 Triple Phosphates, 50, 62 Troy Weight, 11 Tuberculin, 67, 72, 73 Reaction, 73 Tuberculosis, 58 Turpentin, 5 Twitching, 25 Typhoid, 67, 69, 73 Unguentum (Ointment), 8 Unit, Antitoxic, 67 of Length, 1 1 of Volume, 1 1 of Weight, 1 1 Urotropin, 6, 22, 23, 51, 53 Urinary Acidifiers, 6 Urinary Alkalinizers, 6 Urine Increasing, 4 Uterus Contracting, 4 Vaccination, 69 Vaccines, 67 Vaginal Antisepsis, 18 Valerian, 2, 23, 54 Vegetable Diet, 6 Veratrum Viride, 2, 21, 31 Antidote, 32 Veronal, 5, 21, 39 Vinegar (Acetum), 54 Vinum (Wme), 8 Album, 34 Rubrum, 34 Volatile Oils, i Vomiting, 4 Warburg's Tincture, 63 Water (Aqua), 6 Waters, Saline, 49 82 INDEX Wax, 6 Weights, II Whisky (Spiritus Frumenti), 33 White Wine, 34 Wine (Vinum), 8 Wineglassful, 12 Wine Measure, 11 Wolfsbane, 30 Yellow Oxid of Mercury, 53 Zinc, 23, 53 Oxid, I Sulphate, 24, 53 m ^