§1111 CORNELL UNIVERSITY LIBRARY Cornell University Library QK 99.L79 pt.3 3 1924 024 758 330 ...-.I Cornell University Library The original of this book is in the Cornell University Library. There are no known copyrigtit restrictions in the United States on the use of the text. http://www.archive.org/details/cu31924024758330 Bulletin No. 9. 1907. Reproduction Series, No. 5 BULLETIN &» of the Q**> LLOYD LIBRARY of BOTANY, PHARMACY and MATERIA MEDICA J. U. & C. G. LLOYD CINCINNATI, OHIO REPRODUCTION SERIES, No. 5 AN INVESTIGATION OF THE PROPERTIES OF THE SAN- GUINARIA CANADENSIS; or PUCCOON By William Downey, of Maryland Member of the American Linnean and Philadelphia Medical Societies TRAVELS THROUGH THE INTERIOR PARTS OF NORTH AMERICA IN THE YEARS 1766, 1767 AND 1768 By J. Carver, Esq. Captain of a company of provincial troops during the late war with France. Illustrated with Copper Plates. London. Printed for the Author, and sold by J. Walter, at Charing-cross, and S. Crowder, in Paternoster Row. MDCCLXXVIH LIBELLUS DE USU MEDICO PULSATILLA NIGRICANTIS By Antonius StOrck. MDCCLXXI 0»V Q K qcf f ,t. t-3 Capi: i JOJVATHAN CAR VER . t^ww Original Picture tns-m&f/ajbfato'n/ 0//&* M.T>.^. fiiMs/tsd as lA£ Jet direct, ty R.ftavdrtJV, "vfl-i.nzai SiTurn-rttlc Jlptdorn.fov'lS; i ySp , CAPTAIN JONATHAN CARVER. Our Frontispiece portrait of Carver is from the 3rd edition of his Travels, published in 1781 by John Coakley Lettsom, who purchased that edition, and the plates. Jonathan Carver was born in 1732, at Stillwater, in the province of Con- necticut. He was a grandson of William Joseph Carver, of Wigan, in Lan- cashire, England. At the age of 18, he purchased an Ensigncy in Connect- icut, obtaining afterward the command of a company. Under General Webb, he took part in the battle of Fort William Henry, where General Montcalm of the French and Indian army was victorious. In 1758 he served as second lieutenant of Captain Hawks' company, commanded by Colonel Oliver Part- ridge, in the invasion of Canada, and in 1760, he was made Captain of a com- pany in Colonel Salstonstall's regiment. In 1762 he commanded a company of infantry in Colonel Salstonstall's regiment. In all of these positions he ac- quitted himself admirably, both as concerns integrity and courage. The year after accepting his commission under Colonel Salstonstall, came the Peace of Versailles, 1763, when Carver retired from the army. But he was not content to remain in the lines of civil industry, and struck out into the forests of the great American West and Northwest, as an explorer. Of rounded experience and good education, he was excellently qualified for descriptive writing, his narratives being both interesting and instructive. Lake Pepin and its vicinity took much of his time, and "Carver's Travels" concern much of that part of America, as regards quadrupeds, birds, fish, de- scriptions of the natives, vegetation and insects. The portion reproduced in the accompanying Bulletin is that which concerns trees, shrubs, roots, herbs and flowers. In addition to the work now known as "Carver's Travels," Carver issued a pamphlet of fifty-four pages, on the subject of tobacco, accompanying same by two engravings of the plant, and an account of its cultivation on the Amer- ican continent. (See Dr. Lettsom's edition of Carver's Travels.) Captain Carver was rather above the middle stature, muscular in build, and of a florid complexion. He was sociable and affable with friends, but reserved when among strangers. In addition to his scientific descriptions, he touched the poetic, Dr. Lettsom stating that his verses "afford proofs of his lively imagination, and the harmony of his versification." Notwithstanding the fact that Carver was very religious, and was consid- ered to be a very moral and upright man, he deserted his American wife and children, and went to England, where he again married, thus casting a blot upon his record. 4 CAPTAIN JONA THAN CAR VER. After reaching England, 1769, and publishing his Travels, he became dis- tressed in mind, body, and finances, and in 1779, in order to exist, he served as clerk in a lottery office. His vitality and strength were much reduced by depression of mind and body, as well as by the inroads of poverty, and on the 31st day of January, 1780, in the 48th year of his age, he died and was in- terred in Holywell-Mount burying ground, England. A detailed biography of Carver may be found in the Dictionary of Na- tional Biography, by Leslie Stephens. Our brief notice is condensed, mostly, from Dr. Lettsom's Introduction to the 3rd Edition of the work. In this con- nection it may be stated that Dr. Lettsom's interest in Carver led him in the dark times of Carver's later life to devote both care and money in Carver's behalf, and to contribute much to the support of his English family, giving them the entire returns from the subscriptions to the third edition of the work, for which he, (Lettsom), had paid all expenses. J. U. L. AN INVESTIGATION of the PROPERTIES OF THE SANGUINARIA CANADENSIS; OR PUCCOON. BY WILLIAM DOWNEY, OF MARYLAND. — MEMBER OF THE AMERICAN LINNEAN AND PHILADELPHIA MEDICAL SOCIETIES. " Let no presuming impious railer tax Creative wisdom, as if aught was form'd In vain, or nought for admirable ends." THOMPSON. Printed, for the Author, by Eaken & Mecum. (1803.) 4? AN INAUGURAL EXPERIMENTAL INQUIRY, FOR THE DEGREE OF DOCTOR OF MEDICINE. SUBMITTED TO THE EXAMINATION OF THE REVEREND JOHN ANDREWS, D. D. (PROVOST PRO TEMPORE), THE TRUSTEES AND MEDICAL PROFESSORS OF THE UNIVERSITY OF PENNSYLVANIA, ON THE EIGHTH DAY OF JUNE, 1803. TO DOCTOR RICHARD PINDELL, of maryland. Sir, IN the dedication of this, the inaugural fruits of my medical education, commenced under your direction, I shall not consider, that any of my numerous obligations to you, which I with pleasure, thus publicly acknowledge, will be obliterated. Was my dissertation more worthy your notice, your virtues as a citizen, and your merits as a professional character, would alone claim this of me. The friendly instruction which you were ever ready to communicate, and the polite attention which I received from you and your amiable family, during my residence in it, shall always be recollected with gratitude. And that you may long enjoy that happiness, which it is your constant endeavour to communicate to others, is the sincere wish of Your much obliged Friend, and Grateful Pupil, THE AUTHOR. TO BENJAMIN SMITH BARTON, M. D. PROFESSOR OF MATERIA MEDICA, NATURAL HISTORY AND BOTANY, IN THE UNIVERSITY OF PENNSYLVANIA, THIS DISSERTATION IS INSCRIBED, AS A TRIBUTE OF RESPECT AND GRATI- TUDE FOR NUMEROUS FAVOURS CONFERRED UPON HIS FRIEND, AND HUMBLE SERVANT, THE AUTHOR. ALSO, TO DOCTOR FREDERICK DORSEY, OF MARYLAND, THIS IS INSCRIBED, AS A MARK OF HIGH ESTIMATION, AND AS AN ACKNOWLEDGMENT OF THE MANY ACTS OF KINDNESS SHEWN DURING THE PUPILAGE OF HIS SINCERE FRIEND, THE AUTHOR. EXPLANATION OF THE PLATE. A. THE tuberous, premorse root. B. A young involved leaf as it appears with the flower. C. An expanded leaf after the flower. D. An opening corolla, shewing d. the calyx, which is a two-leaved perianth, and falls off as soon as the flower be- gins to expand itself. E. The scape supporting the corolla fully ex- panded. F. The pericarpium, which is oblong, ventri- cose, and bivalved; crowned, with its sulcated stigma. WiBa^tram,, (Ul, INTRODUCTION. WHEN we take a view of the vast number of vegetables with which our country is adorned, we must candidly acknowledge that our ac- quaintance with their medical properties, is ex- tremely limited indeed. The investigation of their uses in the arts and as medicines, is an ob- ject of some importance to society. There is, perhaps, no portion of the globe that has been more highly favoured by nature in esculent and medicinal vegetables. The zea (maize) and po- tatoes, as articles of diet, stand unequalled; the podophyllum peltatum, nicotiana, spigelia and what has been emphatically called the vegetable antimony , the eupatorium perfoliatum, are medi- cines not inferior to any yet discovered. An in- finite number yet remain to be investigated. To increase the list of articles in the Materia Med- ica, is not, however, a desirable object; but to expunge those which are nearly inert, and in- crease the number of active ones is certainly of the first importance. This taken into consider- ation, and with a view to the more easy procure- ment of our medicines, is of sufficient conse- quence to stimulate to an examination of our in- digenous vegetables. I have made a feeble attempt to investigate the properties and uses of the Sanguinaria Cana- densis, a plant peculiar to our country. Most of B the experiments have been repeatedly made, and are related with as much precision as I was ca- pable of. Any errors which may have been com- mitted, were through my inexperience in the business of experimenting. Circumstanced as I have been, little more has been done by me than the simple introduction of the subject. It is well worthy further investigation, both as it respects the science of medicine and the arts. BOTANICAL ARRANGEMENT. T HE genus Sanguinaria belongs to Linnaeus's twenty-seventh natural order, Rhce- deae. In his sexual system he places it in the class polyandria and order monogynia. The characters which he gives of the fructification are as follows : * Cal. Petals eight,t oblong, obtuse, most ex- panding; the alternate ones interior, nar- rower. Stam. Filaments very numerous, simple, shorter than the coral. Anthers simple. PlST. Germ oblong, compressed. Style none. Stigma thickish, two furrowed with a stria the heighth of the stamens, permanent. Per. Capsule oblong, bellied, acute at both ends, two valved, seeds very numerous, round and pointed. * Translation by the Litchfield society. t From eight to fourteen. [ 12 ] DESCRIPTION OF THE PLANT. ist. Root. Is of a very indefinite size, varying in thickness from one fourth to half an inch in diameter, and in length from three to four inches. It is sometimes pretty straight, with a curvature at each end; that from which the stalk proceeds is always to be found, but the other is frequently a wanting, hav- ing the appearance of being broken. Num- erous stringy fibres of two or three inches in length are observed to originate from the body of the root. A coloured liquor, that stains paper of a beautiful orange col- our, is thrown out when a root is broken, from a great number of very minute veins. 2d. The petiole or foot-stalk of the leaf is round, generally from six to eight inches in length and thickness of a quill. 3d. The scapus or stalk which supports the flower, is of a like length with the petiole, but is not quite so thick. Both of them, when broken or squeezed, emit a coloured liquor, which stains of a very pale yellow. Near their origin from the root they are of a red- dish colour, which becomes much more faint near the leaf. 4th. The leaves are cordate and lobate. The number of lobes are mostly five or seven, and their edges have a number of small in- dentations of unequal depths. There is but one leaf to a stalk, which stands nearly in a horizontal direction from the top of the [ 13 J stalk. On each lobe, one large fibre of a very light yellow colour, may be seen run- ning from the stalk, and many smaller ones branching from it in all directions. OF ITS NATURAL HISTORY. The plant which is the subject of the pre- sent enquiry, is known by different appellations, in America, as the puccoon, bloodwort, red root, Indian paint, turmeric, &c. Perhaps it is one of the most abundant vegetables of our country. In the Florida's it is found to grow plentifully, and Professor Barton informs me, he has seen it as far north as lati- tude 43 , and imagines it extremely probable, that it extends much farther. We find it gene- rally inhabiting a rich loose soil, and the declivi- ties of hills. It is seldom or never found to grow in lands, which have been cleared of their tim- ber, or in a state of cultivation. Its flowers gen- erally appear about the first of April, and before its leaves put out. ANALYSIS OF THE ROOT. EXPERIMENT I. Having obtained a quantity of the root dried, and reduced to a gross powder, six ounces of water were poured on two ounces of it; after standing twelve hours, the whole was subjected to a low degree of heat in a glass retort, to which a receiver was properly adapted. At the expira- tion of three hours, the liquor which had passed into the receiver, was examined, and found to be 2 [ H 1 perfectly colourless and insipid. On increasing the heat, a fluid slightly coloured, came over, which had the peculiar smell of the recent root, and was considerably acrid in the fauces. Nei- ther the first nor the last portion was altered by the addition of a solution of the oxy-sulphate of iron. Paper stained with litmus underwent no change. EXPERIMENT II. Six ounces of alkohol were digested in the sun, and one ounce and a half of the root, dried and reduced to a coarse powder, for the space of seven days; it was then decanted, and a fresh quantity added; after standing also the same length of time, it was put with the first portion in a glass vessel, and exposed to evaporation, in a gentle heat. Ninety-eight grains of resin, and extractive matter of a beautiful crimson co- lour, were obtained, of a warm agreeable bitter taste. One dram of this was triturated in a glass vessel, with some warm water, which was after- wards passed through a filter, and evaporated. On drying, and collecting that which was inso- luble, in water, it was found to weigh sixteen grains; the saponaceous or extractive matter, which was soluble in alkohol, as well as water, weighed thirty-eight grains. In the course of the experiment six grains were lost. HAVING dried the roots on which the al- kohol had been digested, a quantity of boiling water was poured on them, which, after standing a short time, was passed through a filter, and evaporated. One dram two scruples of gum- mous matter were obtained, of a dark colour, and an acrid bitter taste: a small quantity dis- [ i5 J solved in the saliva, and swallowed, produced considerable irritation in the fauces, which con- tinued for several hours. To ascertain what action the different prin- ciples of the root, had on the human body, in a state of combination, and when separated, the following experiments were made : EXPERIMENT III. Having breakfasted at eight o'clock, I took twenty grains of the recent root two hours after, my pulse beating seventy-six strokes in a minute. Min 5 [ 10 | 15 | 20 | 25 | 30 | 35 | 40 | 45 | 50 | 55 | 60 | 65 | 70 Puis. 76 | 78 | 80 J 84 | 86 | 86 | 87 | 84 | 82 | 85 | 80 | 77 | 74 | 75 M. 75 | 80 | 85 [ 90 P. 73 | 72 | 73 | 74 In ten minutes I had a burning sensation at my stomach, pulse full and strong; twenty- five, a considerable nausea came on, my pulse very irregular, and not so full; forty, I had a slight head-ach, my face very pale; fifty, the nausea returning at intervals, rendered my pulse extremely irregular, in fullness and force. About three hours from the time of taking it, it purged me gently two or three times. EXPERIMENT IV. To my friend and fellow graduate, Mr. Young, four hours after dining lightly, I gave twenty-three grains of the pulverized root, made into pills, with honey. In fifteen minutes he [ 16 ] complained of a burning at his stomach, his pulse very quick, without much fullness ; thirty, he had a great nausea ; and in thirty-five, it ope- rated most violently as an emetic, producing six or seven full vomitings. He drank a considera- ble quantity of warm tea, with the view of assist- ing the operation, and to allay the violent irrita- tion which was produced in his throat. All the contents of his stomach, as well as the tea, on being discharged, were of a colour similar to the decoction of the root. EXPERIMENT V. Three hours after dining lightly on veal and potatoes, my friend Mr. Rees, took eight grains of the extract obtained by alkohol from the dried root, his pulse beating eighty strokes in a minute. Min. 5 | 10 | 15 | 20 | 25 | 30 | 35 [ 40 | 45 1 50 | 55 1 60 I 65 Puis. 80 | 82 | 82 | 80 | 82 | 84 | 86 | 84 | 84 | 85 | 86 | 88 | 89 In fifteen minutes he had a warmth at his stomach, which he compared to that produced by camphor, his pulse a little fuller; twenty-five, his pulse was strong and full; thirty-five, a slight nausea commenced; forty-five, he had eructations of wind from his stomach; sixty- five, he had one gentle motion to vomit. EXPERIMENT VI. To my friend, Mr. Young, I gave eight grains of the extract, obtained by decoction, with water, and evaporation, his pulse perform- ing only fifty-eight strokes in a minute: in [ i7 1 twenty minutes, his pulse was increased to sixty- two, and had a warmth at his stomach: when forty minutes had elapsed, he became much af- fected with nausea, and was shortly after relieved from every disagreeable sensation, by discharg- ing the contents of his stomach. It produced only two motions and those very gentle. He ob- served to me, that in this, as also in the former experiment, he experienced some difficulty in discharging his urine, having somewhat of an ardor urinae. EXPERIMENT VII. HAVING breakfasted at eight o'clock. I took eight grains of the saponaceous or extract- ive matter, at half past ten, my friend Mr. Wal- ker, attending to my pulse which was at its standard seventy-six. Min. 5 | 10 | 15 | 20 | 25 | 30 | 35 | 40 | 45 | 50 | 55 | 60 | 65 | 70 Puis. 76 | 77 | 77 | 79 | 78 | 79 | 78 | 78 | 80 | 81 | 79 | 78 | 77 | 75 M. 75 | 80 1 85 | 9 P. 76 | 76 | 75 | 76 In twenty minutes I had a slight nausea, my pulse diminished in fullness and force; thir- ty, my pulse very small and quick; forty, I had a disposition to puke, which, however, continued but for a very short time ; fifty, the nausea had nearly disappeared, and my pulse became consi- derably fuller; seventy, my pulse was nearly na- tural in fullness and force, only being a little ir- regular. C [ 18 ] EXPERIMENT VIII. To my friend Mr. Bartram, four hours after taking breakfast, I gave eight grains of the gum- mous matter, his pulse beating seventy-eight strokes in a minute. Min. 5 1 10 | 15 | 20 | 25 | 30 1 35 | 40 | 45 | 50 [ 55 | 60 Puis. 78 I 78 j 80 | 81 | 80 | 83 I 83 I 82 I 80 I 80 I 78 I 82 In fifteen minutes a slight nausea came on with a burning at his stomach; forty, he com- plained of a head-ach, the nausea, at intervals, much more violent; sixty, he was vomited twice, the motions were pretty strong. EXPERIMENT IX. Two hours after breakfasting, my pulse at seventy-four, I took eight grains of the resin, my friend Mr. Walker attending to my pulse. Min. 5 | 10 j 15 | 20 | 25 | 30 | 35 | 40 | 45 j 50 | 55 [ 60 1 65 | 70 Puis. 75 | 75 | 76 | 77 | 77 | 76 | 75 | 77 | 75 | 74 | 74 | 73 ! 74 | 74 In twenty minutes my pulse was a little fuller, with an agreeable sensation at my sto- mach ; from this time, through the whole course of the experiment, there was no perceptible change in my pulse, or my feelings, except what might be occasioned by continuing in the same posture for such a length of time. [ i9l ANALYSIS OF THE LEAVES. EXPERIMENT X. ONE half ounce of the leaves was boiled for half an hour, with a pint of water, which was then poured through a filter, and evaporated. Fifty-eight grains of a dark coloured extract were obtained, of a pleasant sub-acid taste. To the same leaves which were previously dried in the sun was added a portion of alkohol, which after digesting in a gentle heat for three days, was decanted and evaporated in a glass vessel. Twelve grains of resinous matter were obtained, which was nearly of an insipid taste. To the fifty-eight grains of extract were then added, two ounces of alkohol, which after standing four days in the sun, was poured off and evaporated. Eighteen grains of saponaceous or extractive matter, were obtained. EXPERIMENT XL My friend and fellow graduate, Mr. Pender- grast, two hours after breakfasting, took four grains of the leaves powdered and made into pills, his pulse at seventy-six strokes in a mi- nute. Min. 5 | 10 | 15 | 20 | 25 | 30 | 35 | 40 | 45 | 50 | 55 | 60 1 65 | 70 Pvls. 76 | 78 | 79 | 80 | 80 | 82 | 80 | 82 | 78 | 77 | 74 | 72 | 74 | 76 M. 75 | 80 P. 76 | 75 In fifteen minutes his pulse became fuller, and he had a sensation of warmth at his sto- mach; twenty- five he had a fullness in his head [ 20 ] with vertigo; forty, he complained of great de- bility and head-ach ; sixty, he was affected with slight tremors, and very frequent yawning; eigh- ty, his sensations were natural in every respect, but for a slight sickness at his stomach, which continued for several hours after. EXPERIMENT XII. Two hours after taking a light breakfast, I took eight grains of the leaves made into pills, my friend Mr. Walmsley attending to my pulse, which was at its standard seventy-six. Min. 5 | 10 | 15 | 20 | 25 | 30 [ 35 | 40 | 45 1 50 | 55 | 60 [ 65 | 70 Puis. 76 I 76 I 76 | 78 I 80 | 82 | 83 | 84 J 80 | 78 I 76 J 75 | 74 | 74 M. 75 | 80 | 85 P. 73 | 77 I 76 In fifteen minutes I had a warmth at my stomach; twenty-five, my face was flushed, and had a fullness in my head with a slight vertigo ; thirty, my wrists were cold, and a profuse sweat on my forehead ; forty, a slight nausea came on, my pulse small and quick; fifty-five, my pulse was somewhat fuller, the affection of my head still continued, with slight involuntary motions of my muscles ; eighty, my pulse was nearly natural, but I felt extremely languid, with a dull head-ach, which did not leave me for several hours. EXPERIMENT XIII. My pulse at its standard seventy-six, I took four grains of the extract obtained by decoction with water and evaporation. [ 21 ] Min. | 5 | 10 | 15 | 20 | 25 | 30 | 35 | 40 | 45 | 50 | 55 | 60 | 65 Puis. 76 I 76 | 76 | 78 I 80 | 82 | 84 | 86 I 84 | 82 | 82 | 80 | 78 | 76 M. 70 1 75 | 80 | 85 | 90 | 95 | 100 P. 75 | 74 | 72 | 73 | 74 | 73 | 76 In twenty-five minutes I had a pleasant warmth at my stomach, my pulse full; thirty- five, my pulse was rather small and quick, with considerable tension; forty-five I was affected with tremors, as in the preceding experiment; seventy-five, I had a dull pain directly over my eyes, and felt extremely languid ; ninety-five, my pulse was smaller than usual, and I had a dis- agreeable sensation at my stomach, that conti- nued for the remainder of the day. OF THE PERICARPIUM, OR SEED VESSEL AND SEEDS. EXPERIMENT XIV. Having procured two drams of the seed vessels and seeds not arrived at maturity, six ounce measures of water were boiled on them, until evaporated to two. Of this I took two dram measures, my friend Mr. Walmsley at- tending to my pulse. Min. | 5 | 10 | 15 | 20 | 25 | 30 1 35 ] 40 | 45 | 50 | 55 | 60 | 65 Puis. 76 | 76 | 78 | 82 | 82 | 80 | 83 | 83 | 81 | 82 | 79 | 77 | 79 | 81 M. 70 | 75 | 80 1 85 | 90 P. 76 | 75 I 75 | 77 | 76 In twenty minutes not perceiving that any other effect was produced than increasing my pulse a little in frequency, I took two drams [ 22 ] more ; thirty-five, I had a glow of warmth over my body; forty- five, I took three drams more; fifty, I perspired freely, my pulse tense and quick, though not full; seventy, my pulse was extremely irregular; a torpor of my whole system came on, with very frequent yawning; ninety, my pulse nearly as full as usual, though not so strong, and fluctuating. I was not en- tirely free from the effects of it, in the space of two hours. EXPERIMENT XV. My friend Mr. Wootton, two hours after dining, took five dram measures of the decoc- tion, his pulse at eighty strokes in a minute. Min. 5 | 10 | 15 | 20 | 25 1 30 | 35 | 40 | 45 | 50 [ 55 | 60 1 65 j 70 Puis. 80 j 83 | 84 | 87 | 88 | 86 j 84 j 85 I 83 I 81 I 79 I 77 | 78 j 80 M. 75 1 80 | 85 | 90 P. 81 | 79 I 78 | 78 In fifteen minutes his pulse was very strong and full; twenty it became smaller and tense; forty, his pulse was remarkably small and quick; fifty-five, he complained of great languor, with an irresistible propensity to yawn; his counte- nance pale: he mentioned that his vision was somewhat affected; the pupils of his eyes were evidently dilated more than usual ; ninety, his pulse was nearly of its natural fulness, though very irregular, the languor still continuing, as also the propensity to yawn for some time after- wards. [ 2 3 ] REMARKS ON THE PRECEDING EXPERIMENTS. From the result of the two first experi- ments, it appears that there is a gum, a resin, and a saponaceous or extractive matter in the root, but that the former preponderates consi- derably. In the leaves a still larger proportion is found to exist, and a much smaller quantity of saponaceous or extractive matter. By experiment fourth, it is shewn, that the root of our plant is endowed with powerful eme- tic qualities, when taken in the dose of fifteen or twenty grains. But in consequence of the irrita- tion which is produced in the fauces, it is proba- ble, that in the form of a powder, it will never come into general use. This inconvenience may, however, be obviated, by giving it in form of a decoction or extract. Eight grains acted as a very gentle emetic in experiment sixth, without having any such effect. It is but little inferior to the ipecacuanha, either in the certainty or speedi- ness of its operation. THE principle of activity resides chiefly in the gum and saponaceous or extractive matter, but more especially in the former. The resin possesses little or no activity. Perhaps the most certain preparation as an emetic, would be the gum; though combined with the saponaceous matter, as I have already said, it operates pretty certainly. The primary and most prominent effects induced by it, were a warmth at the stomach, an increase in the frequency and force of the pulse ; [ 24 J and if in a considerable dose, nausea and vomit- ing, in a smaller one, it increased in a remarka- ble manner the appetite. In all the experiments it had a tendency to produce costiveness, except in the third, when it acted gently cathartic. The powder of the root may be given as an emetic for an adult, in the dose of fifteen or twen- ty grains, made into pills ; otherwise a consider- able irritation will be produced in the fauces on taking it. As a stimulating tonic, two or four grains may be taken, if nausea be produced, the dose must be diminished. I have repeatedly ex- perienced very sensible effects from taking one single grain. The experiments xii, xiii and xiv, evince a difference in the properties of the leaves and root* Not only in these cases which are re- lated, but also in several others not mentioned, they evidently induced tremors, head-ach, and a great torpor of the system. Such effects are only induced by substances, deleterious to the human constitution. The few experiments which I made with the unripe seeds, convinced me that they pos- sessed a very considerable influence over the pulse, and a stupifying or narcotic quality, t Not * That different parts of the same vegetable should possess powers extremely dissimilar, is a circumstance which frequently occurs, thus, in the Podophyllum Peltatum (or May apple,) a plant nearly allied in its botanical affinities to the Sanguinaria ; we find the fruit esculent, the leaves deleterious, and the root cathartic. This, like many of the mys- terious operations of nature, claims our admiration, though incapable of explanation. t Professor Barton, in his Essay towards a Materia Medica of the United States, mentions, " that the seeds appear to possess nearly the " same quality as the seeds of the Datura Stramonium," which are pow- erfully narcotic. [ 25 J being able to procure any of the ripe seeds, which, in all probability, are more powerful, I was prevented from entering so fully into this part of my subject as I could have wished. AS A COLOURING MATTER. The juice of the root making a very fine dye of an orange colour, has frequently been used by country people, for the purpose of stain- ing flannels and woollen cloths.* But it unfor- tunately is one of those colours, which require an intermediate substance to give it fixity. For frequent washing, and exposure to the sun, de- stroy it entirely. Considering it of some im- portance, to discover a substance which would give it this permanency, by rendering it insolu- ble in water, I made several experiments — But previously, to ascertain what effects those sub- stances commonly made use of as mordants, would have upon the colouring matter, I made the following : A SMALL quantity of the nitric acid was ad- ded to some of the decoction of the root, which was nearly of a brown colour; a precipitate in- stantly took place, and the liquor changed to a muddy yellow colour. On adding the muriatic acid, the colour was rendered much more vivid, without any precipitation occurring. * Professor Barton informs me, that the Indians also make use of it, as a dye for their baskets and articles of ornament. D [ 26] The sulphuric was attended with the same results as the marine. Sulphate of alumine (or allum,) produced very little change in the colour. Acetate (or sugar of lead,) destroyed the co- lour almost entirely, and after standing some time, a copious precipitate of a whitish appear- ance, fell to the bottom. ') Tartrite of pot-ash (or cream of tartar) pro- duced no perceptible change. Murio-sulphate of tin, produced a beautiful mixed colour, between an orange and a red, without any precipitation taking place. An infusion, as also the alkohol of galls, produced a colour nearly similar to that of the murio-sulphate of tin, but after standing some time, a precipitate took place. On adding the prussiate of pot-ash, a dark coloured precipitate took place, after standing a short time, and the super-natant liquor was per- fectly colourless ; but on pouring in a very small quantity of sulphuric acid, the precipitate was redissolved, and the original colour restored. HAVING premised these experiments, I shall proceed to relate the results of several which were made on pieces of flannel, silk, cot- ton and linen, with a view to discover a proper mordant for them. EXPERIMENT I. TWO ounces of sulphate of alumine (or al- [ 2 7 ] lum,) were dissolved in a pint of water; in the solution the strips of flannel, silk, &c. were boiled for fifteen minutes ; when they were taken out, and thrown into a decoction, made by boiling a quart of water on two ounces of the dried root; after stirring them about for a few minutes, they were taken out and placed in the sun to dry. They had all acquired a deep orange colour; but on boiling them in some water, that of the cotton and linen faded considerably, the flannel and silk were but little changed. EXPERIMENT II. EQUAL quantities of the sulphate of alumine (or allum,) and tartrite of pot-ash (or cream of tartar,) were dissolved in some water, and pieces of flannel, &c. boiled in this solution. On taking them out and dyeing them, they acquired a co- lour nearly similar to that in the first experiment ; but on treating them in the same manner, great part of the colouring matter was washed out, more particularly in the linen and cotton. EXPERIMENT III. A STRONG solution of the acetate (or sugar of lead,) was made with rain water, and the same process performed as in the other experiments. The result was, that the flannel and silk acquired a colour approaching to a pale red ; but was con- siderably changed by boiling; the linen and cot- ton were at first but slightly tinged, and which was entirely washed out. 1 28 ] EXPERIMENT IV. Having dissolved about two ounces of the sulphate of alumine in some boiling water, the different pieces of cloths were immersed in it, and as much caustic pot-ash was added as was sufficient to precipitate the alumine, by uniting to the sulphuric acid, and forming sulphate of pot-ash. After boiling them for some time, they were taken out and dyed; the flannel and silk exhibited a very fine orange colour; the linen and cotton retained much less of the colouring matter. Boiling in water rendered the colour more bright in the flannel and silk, but in the others nearly washed it out. This experiment I varied a little, but not with exactly the same result. Having immersed the bits of flannel, &c. in the solution of allum, they were taken out, and a portion of caustic am- moniac poured on them, which uniting to the acid deposited the alumine on the bits of cloth. They were then dyed, but did not retain the co- louring matter as well as in the other experiment. EXPERIMENT V. THE murio sulphate of tin made use of as a mordant, produced an orange colour tinged with red. Washing in water rendered it somewhat more faint, but both the linen and cotton, as well as the other bits of cloth, remained of a very bright orange. [ 2 9 ] EXPERIMENT VI. DILUTED sulphuric acid was tried, as a mor- dant. All the pieces of cloth exhibited a vivid orange colour, but boiling water washed a consi- derable portion of it out. EXPERIMENT VII. A PIECE of white broad cloth was boiled with a solution of the sulphate of iron, and then dyed. A colour approaching to a drab was pro- duced after washing. OBSERVATIONS ON THE FOREGOING EXPERIMENTS. By the first experiments, it appeared, that the colour was entirely destroyed by some arti- cles, and by others, it acquired different shades, which might be varied at pleasure. In all the experiments made with a view to find a mordant, the flannel and silk acquired a deeper or lighter colour, which could never be entirely washed out. But in none was the orange colour retained so completely as in expe- riment fourth, when the alumine was used as the mordant. The murio-sulphate of tin produced a very handsome colour, which was sufficiently permanent; and was the only mordant that fixed- it on the cotton and linen. UPON the whole, by the foregoing experi- ments, I think it is ascertained that the sulphate 3 [ 3o] of alumine, or the alumine alone, and the murio- sulphate of tin, are tolerable good mordants for flannel, cotton, silk and linen. The colours produced by the puccoon are rich, and might undoubtedly, if taken in hands by one conversant in the business of dyeing, be- come one of their most valuable articles. OF THE PROPERTIES OF THE PUC- COON AS A MEDICINE. We have seen that it is a powerful stimu- lant, and that when taken in certain doses, it ex- cites vomiting. And that in small doses it acts as a general stimulating tonic, as is shewn by its increasing the appetite, and its action on the ar- terial system. It has been placed in the class of emetics by Professor Barton,* which is certainly its pro- per arrangement. Its most prominent effect be- ing to induce vomiting even in moderate doses. The leaves and seeds ought to be classed with the incitants, for they evidently are power- ful and diffusible stimulants. In common with other articles belonging to that class, they sometimes act as diaphoreticsf and diuretics. * See his collections for an essay towards a Materia Medica of the United States. t My much esteemed friend Dr. F. Dorsey, of Maryland, informed me in a letter, that the root was frequently given by farriers to horses, with a view to induce sweating, and to promote the shedding of their old coats of hair. [ 3i ] As an errhine, the root finely pulverized, is perhaps inferior to none; a small quantity snuff- ed up the nose, induces an immense discharge and violent irritation. OF ITS USE IN PARTICULAR DISEASES. i. Intermitting fever. I have been informed by a very intelligent gentleman,* that a spirituous tincture of the roots, is very generally used by the inhabitants of low marshy grounds, in the southern states, as a preventive to the in- termitting fever; and in what is called inward fevers, which is but an inferior grade, and is cured by the same remedies. From its general properties, very probably it might be a very useful medicine in this disease, in some particu- lar states. 2. Dysentery. This being a disease, in the primary states, requiring depletion, and the careful abstinence from stimulating and tonic medicines, would render the use of the puccoon very precarious, but after sufficient evacuations have been made or in chronic cases, it will be found a medicine of great value. In the western parts of this state, I have been told, a decoction of it has been used with great advantage, and from the very commencement of the complaint. Probably it was given in such quantities as to prove emetic, or produce a deter- * Mr. William Bartram. C 32 ] mination to the surface of the body, and thereby induce sweating, which is the practice of some physicians in this disease. 3. Jaundice. The roots dried and re- duced to a powder, was recommended by Colden, in this disorder. The dose, however, which he tells us may be taken, is certainly too large ; few systems would bear more than half the quantity. It is more than probable that our medicine was first introduced as a remedy for this disease, un- der the influence of the absurd doctrine of signa- tures. A similarity subsisting between the co- lour of the juice, and the jaundiced eye, was proof sufficiently strong of the propriety of ad- ministering it. Acting as an emetic, no doubt it eventually proved effectual in some cases. Bi- liary concretions, obstructing the ducts, are not unfrequently forced into the duodenum by the violent agitation induced by an emetic. So far we believe it might, in some instances, be of use in this complaint. 4. Ulcerous sore throats. I would in- fer, from its effects generally, that it will be found a valuable medicine, Where there is a ten- dency to slough, or an accumulation of sordes in the throat, as frequently occurs in what is called the putrid sore throat; if given in sufficient quan- tities to induce vomiting, it would be useful, both by removing this collection, and stimulat- ing to a healthy action. 5. AMMENORRHEA. It is very uncertain whether our medicine possesses any other qua- lity than that of a powerful stimulus, and that its action is upon the system generally. One case, [ 33 1 however, related to me,* seems to shew, that it manifestly exerts an influence, sometimes over the uterine system. A young woman who was pregnant, by taking a small quantity of it, with a view to excite a sweat, produced thereby an abortion. Perhaps, when other remedies fail, in obstructions of the menses, it might be worth while to try it. GONNORRHEA. Doctor Schoepf makes men- tion of a decoction being useful in this com- plaint, though he does not say in what manner it is used. In the first stages no preparation of it can be proper: but in chronic gonnor- rheas or gleets, it will be found a very effec- tual remedy. From one to two drams of the dried root, may be infused in ten ounces of wa- ter, and about two tea-spoonfuls of this injected into the urethra three or four times a day. By this treatment, a young gentleman who had been affected with a gonnorrhea for near four months, and had used the common remedies for this com- plaint without effect, was completely cured. OF ITS EXTERNAL APPLICATION. My amiable and ingenious friend Mr. Grimes, at my request, made a few experi- ments with the root, in ill-conditioned ulcers of long standing. In one or two of the cases, the edges of the ulcers were callous, and a thin icho- rous matter was discharged. No dressings had been applied to them for some time previously, except a plaister of the common unguent, prce. Rub. A portion of the powdered root was sprin- * By Mr. E. Griffiths, one of the Physicians to the Alms'-house. E [ 34 J kled over the ulcers, and then covered with a little common cerate, in which some of the powder was also incorporated. The discharge, by this treatment, was much amended; the cal- lous edges were rendered much softer, and the ulcers in general acquired a healthy appearance. It may be proper to observe, that these changes were effected by only a few applications of it: possibly, if the use of it had been continued for some length of time, a cicatrization might have taken place. The juice of the root has been mentioned as a cure for warts, and against the bite of some particular kinds of snakes. Whether it is enti- tled to any notice as such, I will not pretend to say. With this I conclude my essay;"*conscious of its many imperfections, and that little has been done by me, though a subject of great im- portance, and claiming the attention of physi- cians, as also artists. I cannot, however, take leave of this University, without returning my sincere acknowledgments to the different Pro- fessors, for the much useful information I have received from them; but in a more particular manner to Professors Barton and Wistar, for their friendly attention and kindness to me. THE END. TRAVELS THROUGH THE INTERIOR PARTS O F NORTH-AMERICA, IN THE Years 1766, 1767, and 1768. By J. Q A R V E R, Eso^ CAPTAIN OF A COMPANY OF PROVINCIAL TROOPS DURING THE LATE WAR WITH FRANCE. ILLUSTRATED WITH COPPER PLATES. LONDON: Printed for the AUTHOR ; And Sold by J. Walter, at Charing-cross, and S. Crowder, in Pater-noster Row. MDCCLXXVIII. T O JOSEPH BANKS, Esq. F.R.S. S I R, WHEN the Public are in- formed that I have long had the Honour of your Acquain- tance that my Design in pub- lishing the following Work has re- ceived your Sanction that the Composition of it has stood the Test of your Judgment — and that it is by your Permission a Name so deservedly eminent in the Literary World is prefixed to it, I need not be apprehensive of its Success ; as your DEDICATION. your Patronage will unquestion- ably give them Assurance of its Merit. For this public Testimony of your Favour, in which I pride my- self, accept, Sir, my most grateful Acknowledgments ; and believe me to be with great Respect, Your obedient humble Servant, London, June 20, 1778, J. CARVER. [Travels through the Interior Parts of North-America, in the Years 1766, 1767, and 1 768. J [ 494 ] CHAP. XIX. Of the Trees, Shrubs, Roots, Herbs, Flowers, &c. I SHALL here observe the same me- thod that I have pursued in the pre- ceding chapter, and having given a list of the trees, &c. which are natives of the interior parts of North America, particu- larize such only as differ from the. pro- duce of other countries, or being little known, have not been described. OF TREES. The Oak, the Pine Tree, the Maple, the Ash, the Hemlock, the Bass or White Wood, the Cedar, the Elm, the Birch, the Fir, the Locust Tree, the Poplar, the Wickopic or Suckwic, the Spruce, [ 495 ] Spruce, the Hornbeam, and the Button Wood Tree. The OAK. There are several sorts of oaks in these parts; the black, the white, the red, the yellow, the grey, the swamp oak, and the chesnut oak: the five for- mer vary but little in their external ap- pearance, the shape of the leaves, and the colour of the bark being so much alike, that they are scarcely distinguishable; but the body of the tree when sawed disco- vers the variation, which chiefly consists in the colour of the wood, they being all very hard and proper for building. The swamp oak differs materially from the others both in the shape of the leaf, which is smaller, and in the bark, which is smoother; and likewise as it grows only in a moist gravelly soil. It is esteemed the toughest of all woods, being so strong yet pliable, that it is often made use of instead of whalebone, and is equally serviceable. The chesnut oak also is greatly different from the others, particularly in the shape of the leaf, which much resembles that of the ches- nut tree, and for this reason it is so de- nominated. [ 496 ] nominated. It is neither so strong as the former species, or so tough as the latter, but is of a nature proper to be split into rails for fences, in which state it will en- dure a considerable time. The PINE TREE. That species of the pine tree peculiar to this part of the continent is the white, the quality of which I need not describe, as the timber of it is so well known under the name of deals. It grows here in great plenty, to an amazing height and size, and yields an excellent turpentine, though not in such quantities as those in the northern parts of Europe. The MAPLE. Of this tree there are two sorts, the hard and the soft, both of which yield a luscious juice, from which the Indians by boiling make very good sugar. The sap of the former is much richer and sweeter than the latter, but the soft produces a greater quantity. The wood of the hard maple is very beautifully veined and curled, and when wrought into cabinets, tables, gunstocks, &c. is greatly valued. That of the soft sort differs in its texture, wanting the variegated grain of the hard; it also grows [ 497 ] grows more strait and free from branches, and is more easily split. It likewise may be distinguished from the hard, as this grows in meadows and low-lands, that on the hills and up-lands. The leaves are shaped alike, but those of the soft maple are much the largest, and of a deeper green. The ASH. There are several sorts of this tree in these parts, but that to which I shall confine my description, is the yel- low ash, which is only found near the head branches of the Mississippi. This tree grows to an amazing height, and the body of it is so firm and sound, that the French traders who go into that country from Louisiana to purchase furs make of them periaguays. This they do by ex- cavating them with fire, and when they are completed, convey in them the pro- duce of their trade to New Orleans, where they find a good market both for their vessels and cargoes. The wood of this tree greatly resembles that of the common ash, but it might be distinguished from any other tree by its bark; the ross or outside bark being near eight inches thick, and indented with furrows more than six I i inches [ 498 ] inches deep, which make those that are arrived to a great bulk appear uncom- monly rough ; and by this peculiarity they may be readily known. The rind or inside bark is of the same thickness as that of other trees, but its colour is a fine bright yellow; insomuch that if it is but slightly handled, it will leave a stain on the fingers, which cannot easily be washed away; and if in the spring you peel off the bark, and touch the sap, which then rises between that and the body of the tree, it will leave so deep a tincture that it will require three or four days to wear it off. Many useful quali- ties belonging to this tree I doubt not will be discovered in .time, besides its proving a valuable acquisition to the dyer. The HEMLOCK TREE grows in every part of America in a greater or less degree. It is an ever-green of a very large growth, and has leaves somewhat like that of the yew; it is however quite useless, and only an incumbrance to the ground, the wood being of a very coarse grain, and full of wind-shakes or cracks. The [ 499 ] The BASS or WHITE WOOD is a tree of a middling size, and the whitest and softest wood that grows; when quite dry it swims on the water like a cork; in the settlements the turners make of it bowls, trenchers, and dishes, which wear smooth, and will last a long time; but when applied to any other purpose it is far from durable. The WICKOPICK or SUCKWICK appears to be a species of the white wood, and is distinguished from it by a peculiar quality in the bark, which when pounded and moistened with a little water, in- stantly becomes a matter of the consist- ence and nature of size. With this the Indians pay their canoes, and it greatly exceeds pitch or any other material usu- ally appropriated to that purpose; for be- sides its adhesive quality, it is of so oily a nature, that the water cannot penetrate through it, and its repelling power abates not for a considerable time. The BUTTON WOOD is a tree of the largest size, and might be distinguished by its bark, which is quite smooth and prettily mottled. The wood is very pro- per for the use of cabinet-makers. It is I i 2 covered [ 5oo ] covered with small hard burs which spring from the branches, that appear not unlike buttons, and from these I believe it receives its name. NUT TREES. The Butter or Oilnut, the Walnut, the Hazlenut, the Beechnut, the Pecan- nut, the Chesnut, the Hickory. The BUTTER or OILNUT. As no mention has been made by any authors of this nut, I shall be the more particu- lar in my account of it. The tree grows in meadows, where the soil is rich and warm. The body of it seldom exceeds a yard in circumference, is full of branches, the twigs of which are short and blunt, and its leaves resemble those of the walnut. The nut has a shell like that fruit, which when ripe is more furrowed, and more easily cracked; it is also much longer and larger than a walnut, and contains a greater quantity of kernel, which is very- oily, and of a rich agreeable flavour. I am persuaded that a much purer oil than that of [ 5oi 1 of olives, might be extracted from this nut. The inside bark of this tree dyes a good purple; and it is said, varies in its shade, being either darker or lighter according to the month in which it is gathered. The BEECH NUT. Though this tree grows exactly like that of the same name in Europe, yet it produces nuts equally as good as chesnuts; on which bears, martins, squirrels, partridges, turkies, and many other beasts and birds feed. The nut is contained, whilst growing, in an outside case like that of a chesnut, but not so prickly; and the coat of the inside shell is also smooth like that; only its form is nearly triangular. Vast quanti- ties of them lie scattered about in the woods, and supply with food great num- bers of the creatures just mentioned. The leaves, which are white, continue on the trees during the whole winter. A decoc- tion made of them is a certain and expe- ditious cure for wounds which arise from burning or scalding, as well as a restorative for those members that are nipped by the frost. The PECANNUT is somewhat of the walnut kind, but rather smaller than a I i 3 walnut, [ 502 ] walnut, being about the size of a mid- dling acorn, and of an oval form; the shell is easily cracked, and the kernel shaped like that of a walnut. This tree grows chiefly near the Illinois river. The HICKORY is also of the walnut kind, and bears a fruit nearly like that tree. There are several sorts of them, which vary only in the colour of the wood. Being of a very tough nature, the wood is generally used for the handles of axes, &c. It is also very good fire wood, and as it burns an excellent sugar distills from it. FRUIT TREES. I need not to observe that these are all the spontaneous productions of nature, which have never received the advantages of ingrafting, transplanting, or manur- ing. The crab apple-tree, the plum-tree, and the cherry-tree. The CRAB APPLE-TREE bears a fruit [ 503 ] fruit that is much larger and better fla- voured than those of Europe. The PLUM-TREE. There are two sorts of plums in this country, one a large sort of a purple cast on one side, and red on the reverse, the second totally green, and much smaller. Both these are of a good flavour, and are greatly esteemed by the Indians, whose taste is not refined, but who are satisfied with the productions of nature in their unimproved state. The CHERRY-TREE. There are three sorts of cherries in this country, the black, the red, and the sand cherry; the two latter may with more propriety be ranked among the shrubs, as the bush that bears the sand cherries almost creeps along the ground, and the other rises not above eight or ten feet in height; how- ever I shall give an account of them all in this place. The black cherries are about the size of a currant, and hang in clusters like grapes; the trees which bear them being very fruitful, they are generally loaded, but the fruit is not good to eat, however they give an agreeable flavour to brandy, and turn it to the colour of cla- I i 4 ret. [ 504 ] ret. The red cherries grow in the greatest profusion, and hang in bunches like the black sort just described; so that the bushes which bear them appear at a distance like solid bodies of red matter. Some people admire this fruit, but they partake of the nature and taste of alum, leaving a disagreeable roughness in the throat, and being very astringent. As I have already described the sand cherries, which greatly exceed the two other sorts both in flavor and size, I shall give no further description of them. The wood of the black cherry-tree is very useful, and works well into cabinet ware. SHRUBS. The Willow, Shin Wood, Shumack, Sassafras, the Prickly Ash, Moose Wood, Spoon Wood, Large Elder, Dwarf Elder, Poisonous Elder, Juniper, Shrub Oak, Sweet Fern, the Laurel, the Witch Ha- zle, the Myrtle, Winter Green, the Fe- ver Bush, the Cranberry Bush, the Goos- berry Bush, the Currant Bush, the Whir- tie [ 505 ] tie Berry, the Rasberry, the Black Berry, and the Choak Berry. The WILLOW. There are several species of the willow, the most remarka- ble of which is a small sort that grows on the banks of the Mississippi, and some other places adjacent. The bark of this shrub supplies the beaver with its winter food; and where the water has washed the soil from its roots, they appear to consist of fibres interwoven together like thread, the colour of which is of an in- expressibly fine scarlet; with this the In- dians tinge many of the ornamental parts of their dress. SHIN WOOD. This extraordinary shrub grows in the forests, and rising like a vine, runs near the ground for six or eight feet, and then takes root again; in the same manner taking root, and spring- ing up successively, one stalk covers a large space; this proves very troublesome to the hasty traveller, by striking against his shins, and entangling his legs; from which it has acquired its name. The SASSAFRAS is a wood well known for its medicinal qualities. It might [ 5o6 ] might with equal propriety be termed a tree as a shrub, as it sometimes grows thirty feet high; but in general it does not reach higher than those of the shrub kind. The leaves, which yield an agree- able fragrance, are large and nearly sepa- rated into three divisions. It bears a reddish brown berry of the size and shape of Pi- mento, and which is sometimes used in the colonies as a substitute for that spice. The bark or roots of this tree is infinitely superior to the wood for its use in medi- cine, and I am surprised it is so seldom to be met with, as its efficacy is so much greater. The PRICKLY ASH is a shrub that sometimes grows to the height of ten or fifteen feet, and has a leaf exactly resem- bling that of an ash, but it receives the epithet to its name from the abundance of short thorns with which every branch is covered, and which renders it very troublesome to those who pass through the spot where they grow thick. It also bears a scarlet berry, which when ripe, has a fiery taste like pepper. The bark of this tree, particularly the bark of the roots, is highly esteemed by the natives for its medi- [ 507 ] medicinal qualities. I have already men- tioned one instance of its efficacy, and there is no doubt but that the decoction of it will expeditiously and radically remove all impurities of the blood. The MOOSE WOOD grows about four feet high, and is very full of branches; but what renders it worth no- tice is its bark, which is of so strong and pliable a texture, that being peeled off at any season, and twisted, makes equally as good cordage as hemp. The SPOON WOOD is a species of the laurel, and the wood when sawed re- sembles box wood. The ALDER or ELDER, termed the poisonous elder, nearly resembles the other sorts in its leaves and branches, but it grows much straiter, and is only found in swamps and moist soils. This shrub is endowed with a very extraordinary quality, that renders it poisonous to some constitutions, which it effects if the person only approaches within a few yards of it, whilst others may even chew the leaves or the rind without receiving the least detriment from them: the poison however is not mortal, though it operates very [ 5o8 ] very violently on the infected person, whose body and head swell to an amazing size, and are covered with eruptions, that at their height resemble the confluent small-pox. As it grows also in many of the provinces, the inhabitants cure its venom by drinking saffron tea, and anoint- ing the external parts with a mixture com- posed of cream and marsh mallows. The SHRUB OAK is exactly similar to the oak tree, both in its wood and leaves, and like that it bears an acorn, but it never rises from the ground above four or five feet, growing crooked and knotty. It is found chiefly on a dry gravelly soil. The WITCH HAZLE grows very bushy, about ten feet high, and is co- vered early in May with numerous white blossoms. When this shrub is in bloom, the Indians esteem it a further indication that the frost is entirely gone, and that they might sow their corn. It has been said, that it is possessed of the power of attracting gold or silver, and that twigs of it are made use of to discover where the veins of these metals lie hid; but I am apprehensive that this is only a falla- cious [ 509 ] cious story, and not to be depended on; however that supposition has given it the name of witch hazle. The MYRTLE is a shrub about four or five feet high, the leaves of which are larger than those of the common myrtle, but they smell exactly alike. It bears small berries, which are generally called Bay Berries, and these are full of a gluey substance, which being boiled in water, swims on the surface of it, and becomes a kind of green wax; this is not so valu- able as bees-wax, being of a more brittle nature, but mixed with it makes a good candle, which as it burns sends forth an agreeable scent. WINTER GREEN. This is an ever-green of the species of the myrtle, and is found on dry heaths; the flowers of it are white, and in the form of a rose, but not larger than a silver penny; in the winter it is full of red berries about the size of a sloe, which are smooth and round; these are preserved during the severe season by the snow, and are at that time in the highest perfection. The In- dians eat these berries, esteeming them very balsamic, and invigorating to the stomach. [ Sio J stomach. The people inhabiting the in- terior colonies steep both the sprigs and berries in beer, and use it as a diet-drink for cleansing the blood from scorbutick disorders. The FEVER BUSH grows about five or six feet high; its leaf is like that of a lilach, and it bears a reddish berry of a spicy flavour. The stalks of it are exces- sively brittle. A decoction of the buds or wood is an excellent febrifuge, and from this valuable property it receives its name. It is an ancient Indian remedy for all inflammatory complaints, and like- wise much esteemed on the same account by the inhabitants of the interior parts of the colonies. The CRANBERRY BUSH. Though the fruit of this bush greatly resembles in size and appearance that of the com- mon sort, which grows on a small vine in morasses and bogs, yet the bush runs to the height of ten or twelve feet; but it is very rarely to be met with. As the meadow cranberry, being of a local growth, and flourishing only in morasses, cannot be transplanted or cultivated, the former, if removed at a proper season, would [ 5ii ] would be a valuable acquisition to the garden, and with proper nurture prove equally as good, if not better. The CHOAK BERRY. The shrub thus termed by the natives grows about five or six feet high, and bears a berry about the size of a sloe, of a jet black, which contains several small seeds within the pulp. The juice of this fruit, though not of a disagreeable flavour, is extremely tart, and leaves a roughness in the mouth and throat when eaten, that has gained it the name of choak berry. ROOTS and PLANTS. Elecampane, Spikenard, Angelica, Sar- saparilla, Ginsang, Ground Nuts, Wild Potatoes, Liquorice, Snake Root, Gold Thread, Solomon's Seal, Devil's Bit, Blood Root, Onions, Garlick, Wild Parsnips, Mandrakes, Hellebore White and Black. SPIKENARD, vulgarly called in the colonies Petty-Morrell. This plant ap- pears to be exactly the same as the Asia- tick [ 5" J tick spikenard, so much valued by the ancients. It grows near the sides of brooks in rocky places, and its stem, which is about the size of a goose quill, springs up like that of angelica, reaching about a foot and a half from the ground. It bears bunches of berries in all respects like those of the elder, only rather larger. These are of such a balsamic nature, that when infused in spirits, they make a most palatable and reviving cordial. SARSAPARILLA. The root of this plant, which is the most estimable part of it, is about the size of a goose quill, and runs in different directions, twined and crooked, to a great length in the ground; from the principal stem of it springs many smaller fibres, all of which are tough and flexible. From the root immediately shoots a stalk about a foot and half long which at the top branches into three stems; each of these has three leaves, much of the shape and size of a walnut leaf; and from the fork of each of the three stems grows a bunch of bluish white flowers, resembling those of the spikenard. The bark of the roots, which alone should be used in medicine, is of a bitterish fla- vour, [ 5i3 ] vour, but aromatic. It is deservedly esteemed for its medicinal virtues, being a gentle sudorific, and very powerful in attenuating the blood when impeded by gross humours. GINSANG is a root that was once supposed to grow only in Korea, from whence it was usually exported to Japan, and by that means found its way to Eu- rope; but it has lately been discovered to be also a native of North America, where it grows to as great perfection and is equally valuable. Its root is like a small carrot; but not so taper at the end; it is sometimes divided into two or more branches, in all other respects it resem- bles sarsaparilla in its growth. The taste of the root is bitterish. In the eastern parts of Asia it bears a great price, being there considered as a panacea, and is the last refuge of the inhabitants in all disor- ders. When chewed it certainly is a great strengthener of the stomach. GOLD THREAD. This is a plant of the small vine kind, which grows in swampy places, and lies on the ground. The roots spread themselves just under the surface of the morass, and are easily K k drawn [ 5i4 J drawn up by handfuls. They resemble a large entangled skain of thread of a fine bright gold colour; and I am persuaded would yield a beautiful and permanent yellow dye. It is also greatly esteemed both by the Indians and colonists as a re- medy for any soreness in the mouth, but the taste of it is exquisitely bitter. SOLOMON'S SEAL is a plant that grows on the sides of rivers, and in rich meadow land. It rises in the whole to about three feet high, the stalks being two feet, when the leaves begin to spread themselves and reach a foot further. Every fibre of the root has an impression upon it about the size of a sixpence, which ap- pears as if it was made by a seal, and from these it receives its name. It is greatly valued on account of its being a fine purifier of the blood. DEVIL'S BIT is another wild plant, which grows in the fields and receives its name from a print that seems to be made by teeth in the roots. The In- dians say that this was once an universal remedy for every disorder that human na- ture is incident to; but some of the evil spirits [ 5i5 ] spirits envying mankind the possession of so efficacious a medicine gave the root a bite, which deprived it of a great part of its virtue. BLOOD ROOT. A sort of plantain that springs out of the ground in six or seven long rough leaves, the veins of which are red; the root of it is like a small carrot both in colour and appear- ance; when broken, the inside of it is of a deeper colour than the outside, and distils several drops of juice that look like blood. This is a strong emetic, but a very dan- gerous one. HERBS. Balm, Nettles, Cinque Foil, Eye- bright, Sanicle, Plantain, Rattle Snake Plantain, Poor Robin's Plantain, Toad Plantain, Maiden Hair, Wild Dock, Rock Liverwort, Noble Liverwort, Blood- wort, Wild Beans, Ground Ivy, Water Cresses, Yarrow, May Weed, Gargit, Skunk Cabbage or Poke, Wake Robin, Betony, Scabious, Mullen, Wild Pease, Mouse Ear, Wild Indigo, and Cat Mint. K k 2 SANICLE [ Si6 ] SANICLE has a root which is thick towards the upper part, and full of small fibres below; the leaves of it are broad, roundish, hard, smooth, and of a fine shining green; a stalk rises from these to the height of a foot, which is quite smooth and free from knots, and on the top of it are several small flowers of a reddish white, shaped like a wild rose. A tea made of the root is vulnerary and balsamick. RATTLE SNAKE PLANTAIN. This useful herb is of the plaintain kind, and its leaves, which spread themselves on the ground, are about one inch and half wide, and five inches long; from the centre of these arises a small stalk nearly six inches long, which bears a little white flower; the root is about the size of a goose quill, and much bent and divided into several branches. The leaves of this herb are more efficacious than any other part of it for the bite of the reptile from which it receives its name; and being chewed and applied immediately to the wound, and some of the juice swallowed, seldom fails of averting every dangerous symptom. So convinced are the Indians of [ 5i7 ] of the power of this infallible antidote, that for a trifling bribe of spirituous li- quor, they will at any time permit a rat- tle snake to drive ijiis fangs into their flesh. It is to be remarked that during those months in which the bite of these creatures is most venomous, that this remedy for it is in its greatest perfection, and most luxuriant in its growth. POOR ROBIN'S PLANTAIN is of the same species as the last, but more di- minutive in every respect; it receives its name from its size, and the poor land on which it grows. It is a good medicinal herb, and often administered with success in fevers and internal weakness. TOAD PLANTAIN resembles the common plantain, only it grows much ranker, and is thus denominated because toads love to harbour under it. ROCK LIVERWORT is a sort of liverwort that grows on rocks, and is of the nature of kelp or moss. It is esteemed as an excellent remedy against declines. GARGIT or SKOKE is a large kind of weed, the leaves of which are about six inches long, and two inches and half broad; they resemble those of spinage in K k 3 their [ Si8 ] their colour and texture, but not in shape. Their root is very large, from which spring different stalks that run eight or ten feet high, and are full of red berries; these hang in clusters in the month of Septem- ber, and are generally called pigeon ber- ries, as those birds then feed on them. When the leaves first spring from the ground, after being boiled, they are a nu- tritious and wholesome vegetable, but when they are grown nearly to their full size, they acquire a poisonous quality. The roots applied to the hands and feet of a person afflicted with a fever, prove a very powerful absorbent. SKUNK CABBAGE or POKE is an herb that grows in moist and swampy places. The leaves of it are about a foot long, and six inches broad, nearly oval, but rather pointed. The roots are composed of great numbers of fibres, a lotion of which is made use of by the people in the colonies for the cure of the itch. There issues a strong musky smell from this herb, something like the animal of the same name before described, and on that account it is so termed. WAKE [ 5i9 1 WAKE ROBIN is an herb that grows in swampy lands; its root resembles a small turnip, and if tasted will greatly inflame the tongue, and immediately con- vert it from its natural shape, into a round hard substance; in which state it will continue for some time, and during this no other part of the mouth will be affected. But when dried, it loses its astringent quality, and becomes beneficial to mankind, for if grated into cold water, and taken internally, it is very good for all complaints of the bowels. WILD INDIGO is an herb of the same species as that from whence Indigo is made in the southern colonies. It grows in one stalk to the height of five or six inches from the ground, when it divides into many branches, from which issue a great number of small hard bluish leaves, that spread to a great breadth, and among these it bears a yellow flower; the juice of it has a very disagreeable scent. CAT MINT has a woody root, di- vided into several branches, and it sends forth a stalk about three feet high; the leaves are like those of the nettle or be- tony, and they have a strong smell of K k 4 mint, [ 520 ] mint, with a biting acrid taste; the flowers grow on the tops of the branches, and are of a faint purple or whitish co- lour. It is called cat mint, because it is said, that cats have an antipathy to it, and will not let it grow. It has nearly the virtues of common mint. FLOWERS. Heart's Ease, Lilies red and yellow, Pond Lilies, Cowslips, May Flowers, Jessamine, Honeysuckles, Rock Honey- suckles, Roses red and white, Wild Hol- lyhock, Wild Pinks, Golden Rod. I shall not enter into a minute descrip- tion of the flowers above-recited, but only just observe, that they much resemble those of the same name which grow in Europe, and are as beautiful in colour, and as perfect in odour, as they can be supposed to be in their wild uncultivated state. FARI- [ 5*i ] FARINACEOUS and LEGUMINOUS ROOTS, &c. Maize or Indian Corn, Wild Rice, Beans, the Squash, &c. MAIZE or INDIAN CORN grows to the height of about five or six feet, on a stalk full of joints, which is stiff and solid, and when green, abounding with a sweet juice. The leaves are like those of the reed, about two feet in length, and three or four inches broad. The flowers which are produced at some dis- tance from the fruit on the same plant, grow like the ears of oats, and are some- times white, yellow, or of a purple colour. The seeds are as large as peas, and like them quite naked and smooth, but of a roundish surface, rather compressed. One spike generally consists of about six hundred grains, which are placed closely together in rows to the number of eight or ten, and sometimes twelve. This corn is very wholesome, easy of digestion, and yields as good nourishment as any other sort. [ 522 ] sort. After the Indians have reduced it into meal by pounding it, they make cakes of it and bake them before the fire. I have already mentioned that some na- tions eat it in cakes before it is ripe, in which state it is very agreeable to the palate and extremely nutritive. WILD RICE. This grain, which grows in the greatest plenty throughout the interior parts of North America, is the most valuable of all the spontaneous productions of that country. Exclusive of its utility, as a supply of food for those of the human species who inhabit this part of the continent, and obtained with- out any other trouble than that of ga- thering it in, the sweetness and nutri- tious quality of it attracts an infinite number of wild fowl of every kind, which flock from distant climes to enjoy this rare repast; and by it become inex- pressibly fat and delicious. In future pe- riods it will be of great service to the infant colonies, as it will afford them a present support, until in the course of cultivation other supplies may be pro- duced; whereas in those realms which are not furnished with this bounteous gift [ 523 1 gift of nature, even if the climate is temperate and the soil good, the first settlers are often exposed to great hard- ships from the want of an immediate re- source for necessary food. This useful grain grows in the water where it is about two feet deep, and where it finds a rich muddy soil. The stalks of it, and the branches or ears that bear the seed, re- semble oats both in their appearance and manner of growing. The stalks are full of joints, and rise more than eight feet above the water. The natives gather the grain in the following manner: nearly about the time that it begins to turn from its milky state and to ripen, they run their canoes into the midst of it, and tying bunches of it together just below the ears with bark, leave it in this situation three or four weeks longer, till it is per- fectly ripe. About the latter end of September they return to the river, when each family having its separate allotment, and being able to distinguish their own property by the manner of fastening the sheaves, gather in the portion that be- longs to them. This they do by placing their canoes close to the bunches of rice, in [ 524 ] in such position as to receive the grain when it falls, and then beat it out, with pieces of wood formed for that purpose. Having done this, they dry it with smoke, and afterwards tread or rub off the outside husk; when it is fit for use they put it into the skins of fawns or young buffalos taken off nearly whole for this purpose and sewed into a sort of sack, wherein they preserve it till the return of their harvest. It has been the subject of much speculation why this spontaneous grain is not found in any other regions of America, or in those countries situat- ed in the same parallels of latitude, where the waters are as apparently adapted for its growth as in the climates I treat of. As for instance, none of the coun- tries that lie to the south and east of the great lakes, even from the provinces north of the Carolinas to the extremities of Labradore, produce any of this grain. It is true I found great quantities of it in the watered lands near Detroit, be- tween Lake Huron and Lake Erie, but on enquiry I learned that it never arrived nearer to maturity than just to blossom; after which it appeared blighted, and died I 525 ] died away. This convinces me that the northwest wind, as I have before hinted, is much more powerful in these than in the interior parts; and that it is more inimical to the fruits of the earth, after it has passed over the lakes and become united with the wind which joins it from the frozen regions of the north, than it is farther to the westward. BEANS. These are nearly of the same shape as the European beans, but are not much larger than the smallest size of them. They are boiled by the Indians and eaten chiefly with bear's flesh. The SQUASH. They have also several species of the MELON or PUMPKIN, which by some are called Squashes, and which serve many nations partly as a substitute for bread. Of these there is the round, the crane-neck, the small flat, and the large oblong Squash. The smaller sorts being boiled, are eaten during the summer as vegetables; and are all of a pleasing flavor. The crane- neck, which greatly excels all the others, are usually hung up for a winter's store, and [ 5^6 ] and in this manner might be preserved for several months. I am sensible that I have not treated the foregoing Account of the natural productions of the interior parts of North America with the precision of a naturalist. I have neither enumerated the whole of the trees, shrubs, plants, herbs, &c. that it produces, nor have I divided them into classes according to their different genera after the Linnaean method: the limits of my Work, in its present state, would not permit me to pursue the Subject more copiously. However, if the favour of the Public should render a future edition neces- sary, as I trust, from the number of Subscribers who have already favoured me with their Names, will be the case, I then propose to enlarge it considerably, and to insert many interesting particulars and descriptions, which the size of the present Edition obliges me to curtail or entirely to omit. APPEN- JLNTONII gTORCK, SAC. CMS. REG. APOST. MAJEST. CON- 8IL1ARII AVLICI , ARCHLATRI, IN NOSOCO- JKIO CIVICO PASMARIANO - PHYSICI , BT PLURIUH SOCIETATU« MEMBRI &C. LIBK1LLIJS D E USU MEDICO VINDOBON;©, TYPis JOAN. THOM. Wob. de TRATTNERN, C.*«. 8SO. AUt/E TTPOGR. BT BIBLIOP. MDCCLXXI. PRvEFATIO. WM J*w f~\ ^a[ m (^ muamvis Pulsatilla nigricans nullum * ■ • • - *• hue usque locum inter nerbas officina- les obtineat, earn tamen ad illas jure merito pertinere, experimenta, in hoc libello re- censita, evincunt. His enim comprobatur: Pulsatillum ni-, gricantem esse remedium maxime innocuum, eamque tuto posse eegrotantibus exhiberi & prodesse plurimum in morbis pertina- cissimis. A 2 Uti- 4 PRiEFATio. Utinam primeevi medicimz parentes, & primi rei Herbaria Scriptores tot plantis nomen veneni non imposuissent/ Nam inde contigit, ut omnes fere medici, ad nostra us- que scecula, harum usum sollicite evitaverint, & partem medicince maxime necessariam ne- glexerint, relinquerintque incultam. Venena terrent cegros & inscios, cur au- tem medicos terreant, ignoro. Ego profecto! mihi persuasum habeo, in prudentis medici manu nullum dari vene- num; Etenim is, ratione £? experientia edoctus, debet novisse methodum, qua pa- rentur, dosimque, qua exhibeantur medica- menta efjicacia; debet preeterea novisse mor- bum, in quo recte conveniunt & conferunt, & symptomata, quce similia remedia expo- scunt; debet etiam novisse tempus & stadium morbi, in quo indicantur. His Pr.ruf<-ri.War3ticf|e SSinbblume DESCRIPTIO PLANTS. j! ^ II fl ^ x est °blonga, rugosa, inae- qualiter crassa, perennis, fibro- sa; haec primo vere emittit Fo- lia solummodo radicalia bipinnata, foliolis A 4 con- ape 8 De Pulsatilla nigricante. conserta angustioribus, elongatis, acumina- tis, inaequaliter divisis, obscure virentibus. Antequam foliola penitus evolvantur, ex- surgit caulis unus alterve teres, exfusco viridis, cinctus Involucro nonophyllo, pro- funde multoties ac inaequaliter diviso, externe subfusco, interne obscure viridi; pars caulis, quae supra involucrum emi- net, Florem gerit nudum, hexapetalum, fere clausum, coloris saturations & quasi nigricantis! fundum floris stamina occu- pant filamentis numerosis, flavis, capill- aribus, corolla dimidio brevioribus, an- theris didymis, erectis; Germina in cap- itulum collecta sty lis acuminatis, saturate purpureis terminantur, & in semina abe- unt acuminata, longiori cauda, pilosa, ornata. Crescit haec planta passim in locis apri- cis; floret mense Aprili. Omnes ejus partes, paululum mastica- tae, lingua? acerrimum, urentem, & diu per- De Pulsatilla nigricante. persistentem saporem imprimunt; sola radix mitior est. Datur adhuc alia Pulsatilla species, quae Pulsatilla vulgaris dicitur, seu Ane- mone Pulsatilla Linncei: haec ob copiosam, densamque pubem, qua undique large tegitur, quasi ex viridi canescit; Foliola habet latiora; Florem gerit majorem, erectum, magis apertum, pallide vio- laceum: caeterum omnes plantae partes, etiam diutius masticatae, acres non sunt, & linguam sapore nauseoso ac leviter ama- ricante afficiunt. Aqua inde destillata vix non insipida est. Dum hasc Pulsatilla vulgaris defloruit, tunc incipit nostra Pulsatilla nigricans flo- rere, quam, ut colligentes a priori rite distinguant, & seligant, oro; etenim earum virtutes non videntur esse aequales. Egregius ac Doctissimus Jacobus Well Pharmacopaeus, ad ursum nigrum, mihi ex Pulsatilla nigricante paravit aquam de- stillatam & extractum. A 5 Sum- io De Pulsatilla nigricante. Sumsit is plantam totam cum floribus, abjecta tamen radice, conscissam imposuit cucurbitae vitreae, & adfudit octo partes aquae fontanae, & apposito capitello, ad- junctoque excipulo ad balneum arenae medietatem abstraxit. Hocque abstractum asservavit sub no- mine aquce Destillatce Pulsatilla nigricantis, quae admodum acris & penetrans est. Reliquum adhuc paulisper decoxit, her- bam aliquantulum expressit, percolavit, & colaturam ad extracti mollioris con- sistentiam lenissimo calore fecit evapo- rari. Extractum hocce linguae impositum in principio leniter adstringere videtur, dein pungentes dolores excitat, & tan- dem ardorem diu permanentem pro- ducit. Confeci ex hoc extracto binos pul- veres; primum, qui leviorem extracti dosim continet, nominavi pulverem A., se- De Pulsatilla nigricante. i i secundum vero pulverem B., qui duplam extract! dosim recipit. J?. Extract! Pulsatilla nigricantis gr. VII. Sacchari albi dr. i. m. f. pulv. tenuissimus diu terendo in mortario marmoreo. ^. Extracti Pulsatilla nigricantis gr. XIV Sacchari albi dr. i. m. f. pulvis tenuissimus diu terendo in mortario marmoreo. Ex pulvere A. assumsi quinque grana mane, & eandem dosim vesperi repetii, idque hac ratione praestiti per triduum; & quoniam nullum in me efrectum perce- pi, sumsi grana decern mane & totidem tempore vespertino. Ex hac dosi sensi semper aliquot mi- nutis ab assumtione dolorem lancinantem in oculo dextro, in quo magnam contusio- nem biennio abhinc passus fui; quum ef- fraenes equi currum, cui insidebam, vio- lento concussu invertebant; in reliquo au- 12 De Pulsatilla nigricanti. autem toto corpore nil prorsus incommodi animadverti. Postquam per quinque dies quotidie grana viginti hujus pulveris deglutivissem, nullamque inde in me functionem turba- ri, aut laedi observassem, credidi: tuto & omni jure hunc pulverem posse exhi- beri aegrotantibus. Omnem curam parva pulveris A. do- si inchoavi, & didici dein experimentis iteratis, aegros ejus magnam quantitatem sensim sine omni molestia & noxa ferre. Aliqui acceperunt per diem unam, duas, tresve Drachmas. Dum dofis pulveris A. ad drachmam mediam vel drachmam integram augeba- tur, exhibui tunc pulverem B., ut asger sub minori volumine eandem tamen ex- tracti seu medicamenti portionem aqui- reret. Ex herba sicca paravi infusum sequen- ti modo: Her- De Pulsatilla nigricante. 13 Herbae Pulsatilla nigricantis dr. 1. consciss. infunde s. q. aq. fervid, per J4 hor. vase clauso dein cola- turae lib. 1. adde Sacchari q. s. ad gratiam. S. sumat aeger ter quotidie vasculum unum unciarum trium vel quatuor hujus infusi. Reddidi hoc infusum fortius, dum ad ejusdem colaturae quantitatem dr. ij. vel dr. iij. vel unc. B. adhibui, idque aegri sine molestia tulerunt. Hoc infusum interne, & externe ap- plicatum in fcedis & sordidis ulceribus op- timos quandoque praestitit effectus. Tentavi id etiam in tinaea capitis anti- qua admodum, verum cutis inflammaba- tur, caput vehementer doluit, unde ab ul- teriori experimento abstinendum judicavi. Ex- i4 De Pulsatilla nigricante. EXPERIMENTA EXPERIMENTUM I. Fcemina, 35. annorum, a quinque annis & dimidio brachium sinistrum non poterat movere; erat enim totum rigi- dum, & emaciatum. Causam mali rejecit in morbum rheu- maticum, quo olim per totum corpus la- boravit, & quo disparente brachium cce- pit immobile fieri, & rigescere. Remedia interna & externa huc- usque nil profuerunt; ipsa vis electrica dolorem magnum produxit, sed malum non emendavit. Huic exhibui mane drachmas duas aquae destillatae Pulsatilla nigricantis; ean- dem dosim vesperi iteravi. Primis binis diebus nullam sensit mutationem. Unde tertio die suasi, ut sumeret ma- ne unciam dimidiam, & totidem ad me- ridiem & vesperi. Per- De Pulsatilla nigricante. 15 Percepit tunc vagos & lancinantes in brachio dolores, & noctu pruritum in- gentem. Post octiduum coepit digitos paululum movere, & dolores fuerent frequen- tiores. Dedi dein ter de die unciam integram hujus aquae, & jussi, ut mane & vesperi brachium totum probe fricaretur pannis laneis, & dein lavaretur aliquamdiu ea- dem aqua destillata ex Pulsatilla nigricante. Intra binas septimanas potuit brachium elevari, & digiti movebantur liberius. Debito tempore rediit fluxus men- struus, sed longe copiosior, ac alias esse solebat. Quamdiu menstrua fluebant, aegra nee dolorem, nee pruritum sensit in bra- chio; his autem finientibus novus & val- de molestus ortus est pruritus & compa- ruerunt pustulae rubrae, copiosissimae, quae dein pure replebantur. Dum 1 6 De Pulsatilla nigricante. Dum prims pustulae exsiccatae sunt, & in squammas secesserunt, novae iterum multae eruperunt; hoc aliquoties eodem ordine contigit, & aegra semper inde le- vamen habuit, atque spatio trium fere mensium poterat brachium libere in om- nem partem movere, & eo uti ad soli- tos labores bene peragendos. Eandem remedii dosim usque ad finem curationis semper assumsit, nee abstinuit, dum menstrua fluebant. Neque lotio & lenis frictio brachii fuit intermissa, licet pustulae suppurantes do- luerint acriter & cutis superficies fuerit inflammata; quoniam his externe irritatis motus brachii semper factus est melior & liberior. Unde has molestias aegra pa- tenter tulit. Primis diebus ex usu hujus remedii urina copiose educebatur, & aegra subin- de levem vomendi conatum percepit; caeteroquin de nullo incommodo conque- sta fuit. Ex- De Pulsatilla nigricante. 17 experimentum ii. Sacerdoti, 63. annorum, qui para-, lysi brachii & pedis dextri jam a decern annis laboravit, dedi mane & vesperi unciam dimidiam aquae destillatae Pulsatil- la nigricantis; spatio octidui nil mutatum fuit. Sumsit dein ter de die unciam dimi- diam, mox autem nausea ipsum prehen debat & vomendi conatus. Suasi, ut dosim remedii iterum mi- nueret, verum nee exiguam quantitatem amplius potuit deglutire, quin vomitus moveretur; unde erat ab hoc remedio abstinendum. EXPERIMENTUM III. Fcemina, 28. annorum, ante trien- nuim a foedis venereis ulceribus curata fuit, ab eo autem tempore sensit in om- nibus membris & articulis continuos & dilacerantes dolores, qui quotidie ver- B sus 1 8 De Pulsatilla nigricante. sus horam quartam matutinam multa cum vehementia exacerbabantur. Appetiit quidem, & reliquae functio- nes bonae erant, sed corpus mansit debi- le & emaciatum. Quaecumque adhibita remedia nil le- vaminis adtulerunt, nee juverunt balnea. Huic dedi mane & vesperi unciam dimidiam aqua? destillatae Pulsatilla nigri- cantis, quam bene tulit; urina inde co- piose fluxit, & primis diebus aliquoties solvebatur alvus. Sexto die noctu multum sudavit, & sudor male olebat, dolores minuti sunt, & somnus tranquillus usque ad horam sex- tam matutinam duravit. Octavo die catamenia prodierunt, quae solito longe copiosiora erant; nee dolor colicus, qui alias semper ea praaecesserat, tunc advertebatur. Remedium etiam tempore catameni- orum fuit continuatum; unde sensim re- dierunt vires, habitus corporis iterum in- cre- De Pulsatilla nigricante. 19 crevit, tandem dolores cessarunt, & finita quinta septimana sanitas fuit bona. EXPERIMENTUM IV. Vir, 34. annorum, Gonorrhoea venerea neglecta, & inveterata jam diu vexabatur; praeterea testiculus dexter durus fuit, & mole longe major sinistro. Sumsit mane & vesperi unciam dimi- diam aquae destillatae Pulsatilla nigricantis; primo statim die oriebatur intollerabilis fere ardor urinae; altero die idem ardor continuavit, & multus ichor fcetidus ex- stillavit ex urethra. Tertio die aeger in dimittendo urinam tantum sensit dolorem, ut fere in animi deliquium ceciderit; praescripsi tunc satu- ratum ex herba althaea decoctum, ut copiose id biberet tota die, nee tamen remedii alterius usum interrumperet. Quarto die ardor longe minor fuit, ichoris stillicidium autem adhuc erat copiosius ac die praecedenti. B 2 Quin- 20 De Pulsatilla nigricante. Quinto die omnia fuerunt mitiora, appe- titus bonus, noctes tranquillae. Spatio trium septimanarum usu conti- nuo ejusdem remedii & decocti emol- lientis gonorrhaea fuit integre curata, sed testiculus induratus permansit in eodem statu. EXPERIMENTUM V. Vidua, 42. annorum, tophos venereos in osse frontis, ad sternum, & utramque tibiam habuit, & dolores vehementes in omnibus artubus, qui vesperi semper val- de exacerbabantur ; oculo dextro jam a viginti annis nil vidit, quoniam cornea tota transparens panno erat Obducta; men- struo fluxu jam a binis & dimidio an- nis caruit. Exhibui ei mane & vesperi unciam dimidiam aquae destillatae Pulsatilla nigri- cantis, quam sumsit per octiduum sine effectu; id solum sibi observare visa est, lucem se quamdam confusam oculo, quo jam De Pulsatilla nigricante. 21 jam per viginti annos nil vidit, percipere. Auxi tunc dosim, & dedi ter quotidie unciam dimidiam ejusdem aquae. Post octiduum rediens dixit: dolores nocturnos esse minores, seque posse oculo suo dextro jam colores distinguere. Examinando tophos, inveni eos in fronte longe minores, molliores; reli- qui autem non sunt mutati; pannus in oculo erat tenuis, & hinc inde transpa- rens. Jussi, ut eadem dosi continuaret; quo contigit, ut spatio trium & dimidii men- sium visum in oculo, jam a tot annis ob- fuscato, recuperaverit, ut dolores no- cturni cessarint, disparueruntque tophi in fronte; verum reliqui nee mole nee du- ritie minuebantur; erant tamen absque dolore. His aegra contenta abstinuit a reme- dio, ex cujus usu nil insoliti unquam ob- servavit. B 3 Ex " 22 De Pulsatilla nigricante. experimentum vi. Ancilla, 26. annorum, tophis vene- reis valde magnis a quinque mensibus la- borans in utraque tibia, dolores noctur- nes enormes patitur, & extenuatur fluo- re albo. Tentavi eandem aquam, exhibendo mane unciam dimidiam, & totidem ve- speri. Intra octiduum nil levaminis sensit; suasi, ut ter de die sumeret unciam di- midiam; inde videbantur dolores noctur- ni leviores per aliquot dies; verum pau- lo post eadem cum violentia redierunt. Exhibui tunc ejus aquae unciam inte- gram mane, ad meridiem, & vesperi, ita ut quotidie tres uncias deglutiverit ; ast nee inde malum emendatum fuit, licet per sex septimanas diligenter & magna cum constantia earn assumserit. Hinc ut ab hoc remedio abstineret jussi. Prae- De Pulsatilla nigricante. 23 Praescripsi dein saturatum florum Flam- mulce Jovis infusum, ex quo, spatio trium mensium, integre convaluit, pinguis facta est, & nupsit. EXPERIMENTUM VII. Ancilla, 14. annorum, in tota facie, collo, & pectore ulcera habuit fceda, & fcetido ichore manantia; in hac tentavi pulverem A., exhibendo mane grana decern, totidem ad meridiem, ac vesperi; ulcera jussi bis quotidie infuso florum sam- buci ablui, & dein tegi emplastro dia- pompholygos. Primis quatuordecim diebus omnia vi- debantur mutari in melius; copia ichoris minuebatur, & margines ulcerum futu- ram cicatricem promittebant. Verum haec iterum evanuerunt subito, & ulcera redierunt aeque mala, licet aegra quotidie drachmam integram, dein drach- mam unam & dimidiam hujus pulveris as- sumserit per multas septimanas. B 4 Ex- 24 De Pulsatilla nigricante. Exhibui dein ter quotidie vascula bi- na saturati infusi flammulce Jovis, & bis quotidie conspersi ulcera pulvere ejus- dem plants, & texi emplastro diampom- pholygos; felix inde sequebatur succes- sus; etenim spatio binorum mensium ulce- ra erant firma cicatrice clausa, & sanitas fuit bona. EXPERIMENTUM VIII. Homo, 21. annorum, a pessimis veli- penduli & palati ulceribus venereis cura- tur; manet autem ipsi pertinax admodum ophthalmia, & opacitas in utroque ocu- lo; dextro quidem oculo confuse quae- dam videre potuit, in sinistra autem al- bugo visum penitus impedivit. Parotis dextra jam a longo tempore scirrhosa fuit & magna. Remedia omnis generis mercurialia, antimonialia, aliaque interna & externa, longo & diligenti usu applicata, nihil juve- runt; aeger potius inde vires prosterni, vi- De Pulsatilla nigricante. 25 visum diminui, & appetitum deleri, no- ctesque inquietas reddi conquerebatur. Ideo dabantur ipsi grana viginti pul- veris A. mane & totidem vesperi. Primis octo diebus magnus in oculis dolor ortus est, & copiosissime plorabant oculi. Data dein fuit ter quotidie similis do- sis ejusdem pulveris, & inde sequebatur multa salivatio, qua prodiit gluten tena- cissimum. Salivatio duravit per aliquot dies, & visus in oculo dextro melior factus est, & ad oculum sinistrum ccepit lumen ob- scure penetrare. Cessante salivae fluxu insurgebat diar- rhaea copiosa, foetidissima ; eadem nihi- lominus dosi & eodem remedio continua- vimus, quoniam aeger nequaquam debi- lis reddebatur, & in oculis magnum sen- tiebat levamen. Sponte desiit diarrhaea, & tunc caput ccepit vehementer dolere per biduum. B 5 Spa- 26 De Pulsatilla nigricante. Spatio quinque septimanarum oculo dextro omnia sat bene distinxit, isque fere totus serenus fuit; in sinistra lumen magis percipiebatur, & coepit manifeste dissipari albugo. Aucta tunc dosis remedii fuit, exhi- bendo ter quotidie drachmam dimidiam ejusdem pulveris. Ex hac dosi iterum novus in oculis dolor sequebatur, & dixit aeger: se sen- tire ac si quis cultro aliquid in oculis ab- raderet, nee tamen oculi rubebant, la- chrymae multae exstillarunt, & fluxit uri- na solito longe frequentior & copiosior. Post aliquot dies dolores in oculis re- miserunt, coepit emolliri parotis schirrhosa, & finito secundo mense visus iterum me- lior fuit. Dedimus tunc ter quotidie drachmam dimidiam pulveris B. & hac dosi in quar- tum mensem pereximus, quo tempore aeger utroque oculo bene omnia videre po- De Pulsatilla nigricante. 27 potuit, & simul a parotide scirrhosa inte- gre curatis fuit. EXPERIMENTUM IX. Vir, 35. annorum, crurum paralysi, & ingenti ad os sacrum dolore jam a Ion- go tempore laborat; varia & maxime efficacia remedia nil juvant. Dantur ei grana XV. pulveris A. ma- ne & totidem vesperi. Primis sex diebus dolorem sat acutum in ventre sensit quotiescunque hunc pul- verem assumsit, is autem ultra mediam horam nunquam duravit. Septimo die afficiebatur diarrhaea, & tunc dolores ventris cessarunt. Postquam per 20. dies usus erat hoc pulvere, percepit dolores ardentes, lan- cinantes & vagos a digitis pedum ad in- guina usque; praterea nil mutatum fuit. Dedimus tunc grana XX. ejusdem pulveris bis per diem, & inde aucti sunt dolores in cruribus & praesertim in digi- tis pedum. Post 28 De Pulsatilla nigricante. Post binas septimanas potuit crura ali- quantulum movere, surrexit e lecto, am- bulare tamen non poterat. Exhibebatur tunc bis per diem drach- ma dimidia pulveris A. & dolores in cru- ribus aucti sunt. Octiduo post dolores ad os sacrum ve- hementes adeo fiebant, ut somnum impedi- verint. Sumsit tunc ter de die grana XX. pul- veris B., & mox haimorrhoides coepe- runt copiose fluere per triduum. Finito haimorrhoidum fluxu dolores ossis sacri evanuerunt, & ii in cruribus multum sunt diminuti. Dedimus tunc ter quotidie grana XXX. pulveris B. qua dosi jam per ali- quot septimanas continuat, & dolores in cruribus cessant, aeger surgit e lecto, ambulat solus, sed valde adhuc est de- bilis. Ex- De Pulsatilla nigricante. 29 experimentum x. Vir, 48. annorum, ulcera venerea in faucibus & lingua tota habet, quae re- mediis antevenereis non solum non ce- dunt, sed serpunt semper, & vicinas partes magis in latum & profundum cor- rodunt. Tentavimus pulverem A., exhibendo ter quotidie grana viginti. Per quinque dies nullam vidimus in ulceribus mutationem, sed urina ingenti copia profiuxit. Dedimus tunc ter quotidie grana XXX. ejusdem pulveris, & sensim videbantur puriora fieri ulcera. Demum auximus remedii dosim prae- bendo ter quotidie grana XXX. pulveris B., & hac dosi aeger intra quatuor septi- manas integre curatus est. EXPERIMENTUM XI. Homo, 30. annorum, ex apertis tu- moribus Lymphaticis ulcera habuit ma- gna 30 De Pulsatilla nigricante. gna ad scapulam sinistram, & ad cubitum brachii dextri, genu sinistrum tumuit, & erat immobile. Ulcera tantam seri copiam fundebant continuo, ut aeger caeperit contabescere, licet usus fuerit optimis remediis, & diaeta lactea. Prae nimio in genu dolore nee pedi in- sistere, & minus adhuc ambulare potuit. Exhibuimus ei pulverem A., inci- piendo a granis XV. mane, todidem ad meridiem, & vesperi, sensim auximus dosim, donee ter quotidie drachmam integram hujus pulveris absumserit. Primis diebus sensit dolorem in abdo- mine ex asumpto pulvere, postea au- tem nil amplius incommodi percepit, nee ulla alia in corpore mutatio contigit. Spatio trium mensium ulcera sunt fir- miter consolidata, tumor ad genu fuit multum diminutus, rediit quaedam in ge- nu nobilitas, aeger ambulat, & recupe- rat vires naturales. Ex- De Pulsatilla nigricante. 31 experimentum xii. Ancilla, 24. annorum, ulcus habet foedissimum in lingua, quo lingua fere tota a basi ad apicem usque bifurcata, & erosa fuit. Per multos menses laudatissimis usa est remediis; verum nee mali limites pote- rant coerceri, nee ullum unquam leva- men observabatur. Spatio autem quinque septimanarum ex usu pulveris A. non solum ulcus pu- rum fuit redditum, sed & replebatur pulchra carne, & totum bona cicatrice obducebatur; in apice solummodo levis adhuc excoriatio superest, ad quam de- struendam penitus eodem adhuc pulvere parva dosi utitur. Vires autem habet optimas, & solita servitia omni cum alacritate & constantia peragit. In principio ex usu pulveris tormina sensit; dein autem sequebatur alvi flu- xus 32 De Pulsatilla nigricante. xus, qui omnem ventris dolorem su- stulit. Observavit quoque aegra urinam longe copiosius ab hoc pulvere moveri. Menstrua ipsi redierunt solito tempo- re, & sub usu pulveris erant longe abun- dantiora, & per plures dies durarunt. EXPERIMENTUM XIII. Foemina, 34. annorum, ulcere ve- nereo & carie ossis frontis laborat. Remedia antivenerea diu applicata vix ullum auxilium adferunt. Pulvis autem B. spatio trium mensium cariem destruxit, induxitque firmam & bonam cicatricem. EXPERIMENTUM XIV. Ancilla, 25. annorum, gerit a longo tempore tumorem lymphaticum ad arti- culum genu dextri, qui a perito chirur- go lanceola fuit pertusus, & effluxit mul- ta lympha turbida. Fa- De Pulsatilla nigricante. 33 Facta incisione tumor concidit; verum lymphae stillicidium continuat, genu do- let multum, & aegra incipit contabescere. Praeter alia remedia sumsit decoctum corticis peruviani cum lacte, & externe applicabatur cataplasma ex herbis resol- ventibus, & aqua vegeto-minerali Gou- lardi; malum autem nequaquam fuit emendatum, & genu iterum magis in- tumuit. Datus igitur fuit pulvis B., quo intra paucos dies mitior fiebat dolor in genu, & aegra potuit dormire. Sensim quoque minuebatur lymphae stillicidium, genu detumuit, dolores ces- farunt. Tandem spatio binorum mensium con- solidatum fuit ulcus, aegra ambulat sine omni dolore, recuperat vires, genu ad- huc paulisper tumet. Sub usu pulveris aegra advertit urinam solito copiosiorem cieri, & alvum habuit laxam; praeterea nil insoliti observavit. C Ex- 34 De Pulsatilla nigricante. experimentum xv. Ancilla, ij. annorem, fluore albo venereo, condylomatibus ad pudenda, ul- ceribus faucium & linguae pessime af- ficitur. Consuetis remediis tolluntur condylo- mata, sistiturque fluor albus; ulcera au- tem permanent aeque sordida, & serpunt continue Datur pulvis A., & spatio unius men- sis ulcera omnia sunt optime curata, & rediit robusta sanitas. Urinam primis diebus abundantius moveri sensit aegra ex usu hujus pulveris, aliud nihil insolidi accidit. EXPERIMENTUM XVI. Fcemina, 28. annorum, oculo sini- stra jam ab aliquot annis nil videt, nee lumen distinguit, quoniam pannus crassus totam corneam transparentem occupat. Re- De Pulsatilla nigricante. 35 Remedia interna & externa juvant nihil. Data ideo fuerunt grana XX. pulveris A. mane, totidem circa meridiem, & vesperi. Primis statim diebus enormes in oculo affecto dolores aegra conquerebatur, quo- tiescunque hunc pulverem assumsit. Hi vero sensim mitiores facti sunt, & tandem cessarunt. Decimo quarto die pannus videbatur tenuior, & aegra lumen optime discerne- bat a tenebris. Exhibebantur tunc ter de die grana XV- pulveris B., & haec dosis ad cura- tionem perficiendam suffecit. Etenim spatio binorum fere mensium pannus evanuit, aegra eo oculo omnia vidit, & distinxit. Praeter dolores in oculo affecto, quos primis diebus aegra patiebatur, nullam aliam mutationem in corpore suo per- cepit. C 2 Ex- 36 De Pulsatilla nigricante. experimentum xvii. Ancilla, 25. annorum, tophum ve- nereum habuit ad articulum sinistrum ma- xillae inferioris; hie in suppurationem abiit, & solitis remediis ulcus, inde or- tum, curabatur; remansit tamen quidam tumor, & dolor ingens in parte laesa, & maxillae motus omnis fere erat impossibilis. Datur pulvis A., unde in principio dolores augentur, & aegra cogitur fere omni momento urinam dimittere. Post decern dies maxilla fit mobilior, dolores autem sunt adhuc magni. Spatio sex septimanarum cessant do- lores, tumor evanescit, maxilla liberius movetur, & aegra cibos suos sine mole- stia masticat, & deglutit. EXPERIMENTUM XVIII. Puella, 14. annorum, amaurosi la- borat in utroque oculo, & praeter lumen confusum nil videt, pupillae sunt dilatatae, immobiles. Dan- De Pulsatilla nigricante. 37 Dantur ter quotidie grana XV- pul- veris A., unde sensit in oculis validos dolores. Decimo quarto die jam quaedam vi- dere potuit, & pupillae erant mobiliores. Spatio binorum fere mensium visus integer rediit, pupillae factae sunt natura- les, & optime mobiles. Haec puella primis tribus septimanis ex usu hujus pulveris quotidie bis terve purgata fuit, nee tamen se debilem inde sensit; caeteroquin de nulla re conque- rebatur. EXPERIMENTUM XIX. Puella, 15. annorum, albuginem ha- bet in utroque oculo; videt quidem, sed nee colores nee objecta potest di- stinguere. Varia applicata collyria, aliaque pe- netrantissima ac solventia remedia interne adhibita malum nequaquam emendant. C 3 De- 38 De Pulsatilla nigricante. Demum sumsit ter de die grana XV. pulveris A., unde in principio magnos in oculis dolores sensit, & levi diarrhaea laboravit, post paucos autem dies ccepit visus emendari, & spatio sex septima- narum omnis albugo disparuit; & oculus dexter fuit perfecte curatus; sinister au- tem fuit adhuc debilis; hinc pergit in usu ejusdem pulveris, & spes est: fore ut is quoque integrum suum robur recuperet. EXPERIMENTUM XX. Foemina, 39. annorum, a 14. annis, amaurosi laboravit in oculo dextro, & sinister oculus eodem malo afficiebatur a sesquianno. Misera nil potuit videre, nee diem a nocte discernere, nee sola ambulare. Postquam multa adhibuisset remedia sine omni effectu, sumsit tandem pulve- rem A. Dolores validissimi, dilacerantes, per- terebrantes & lancinantes in oculis a prin- ci- De Pulsatilla nigricante. 39 cipio orti sunt, & coeperunt oculi vehe- menter plorare. Post tres septimanas proruperunt men- ses copiosi, qui jam ab aliquot annis re- tinebantur. Post sex circiter septimanas coepit lu- men clare distinguere, & pupillae in utro- que oculo fiebant mobiles. Quinque nunc menses finiti sunt, qui- bus utitur hoc pulvere, & oculo sinistro objecta videt, colores distinguit, & sola per plateas ambulat; dexter autem ocu- lus male se habet, licet pupilla sit mobi- lior, & luminis sensus penetret; nullus autem color discernitur, nee figura ob- jecti. Ulteriori autem usu hujus pulveris speramus hunc quoque oculum bonum futurum, cum jam quaedam in melius mutatio observetur. iEgra autem est quam contentissima, quoniam uno oculo videt, & sola ara- bulare potest. C 4 Men- 40 De Pulsatilla nigricante. Menstruorum fluxus ipsi omni tertia septimana redit; reliquae corporis actio- nes sunt quam sanissimae. EXPERIMENTUM XXI. Foemina, 33. annorum, primis die- bus puerperii summis in mamma dextra doloribus afficitur; mamma tumet, dura est, rubet. Applicatis bonis remediis dolor mam- ma? cessat, rubedo disparet, durities emollitur, sed mox vehementissimus do- lor occupat aurem utramque, & altero die pus effluit ex utroque meatu audito- rio, & dolor remittit. Hie puris fluxus durat per quinque dies, & tunc sponte sistitur. Triduo post conqueritur aegra de ten- sione in oculis; dicit sese objecta non rite videre; tandem perit totus visus, & oritur amaurosis in utroque oculo. Applicata vesicantia ad nucham & post aures, data remedia purgantia, aliaque de- De Pulsatilla nigricante. 41 derivantia, solventia, discutientia &c, nil levaminis adferunt, & malum durat per septem annos. Nunc sumit per tres & dimidium men- ses pulverem A. & jam sola ambulat, & incipit objecta etiam minora discernere. In principio magnos in oculis dolores ex usu hujus remedii passa est. Menstruorum fluxus semper bonus & regularis fuit. EXPERIMENTUM XXII. Ancilla, 20, annorum, ante medium annum laboravit ophthalmia inflammato- ria in oculo sinistro, quae in suppuratio- nem abiit. Pus corneae laminam exteriorem pe- netravit, & relinquebatur inde crassa ci- catrix, & tota cornea fuit opacata, at- que aegra eo oculo nil poterat videre. Cum incassum tentata fuissent plurima remedia, tandem dabatur pulvis A.; cujus uso spatio binorum menfium cornea C 5 se- 42 De Pulsatilla nigricante. serena & pellucida facta est, cicatrix eva- nuit, & a?gra visum integre recuperavit. Huic aegrs retinebantur menses jam ab integro fere anno, qui mox ab uso hujus pulveris comparuerunt copia bona, & observarunt deinceps semper debitum ordinem, & solitam periodum. EXERIMENTUM XXIII. Mulier, 43, annorum, ex partu dif- ficili afficitur amaurosi utriusque oculi, & jam a binis fere annis nil videt. Exhibetur ei pulvis A., qui in prin- cipio ingentes in oculis dolores produxit; spatio autem septem septimanarum tan- tum boni praestitit, ut aegra jam rite per agat labores domesticos, & sola possit per plateas incedere. EXPERIMENTUM XXIV. Mulier, 40. annorum, dextro oculo nil videt, quoniam lens crystallina grisea est, & penitus opaca. Uti- De Pulsatilla nigricante. 43 Utitur nunc pulvere A. per sex sep- timanas, & lens fit tenuior, & aegra eo oculo jam quaedam videt, distinguit. EXPERIMENTUM XXV. Juvenis, 22. annorum, visum in utro- que oculo adeo debilem habet, ut cha- racteres majoris etiam magnitudinis legere amplius non possit. Penetrantissima ipsi adhibita sunt reme- dia sine omni effectu; nunc per sex se- ptimanas sumit pulverem A.; & jam com- mode legit impressos characteres, & re- liqua omnia objecta melius videt. EXPERIMENTUM XXVI. Vir, 42, annorum, casu fortuito sibi vulnus inflixit in medio corneae oculi dex- tri; magna sequebatur inflammatio, quae repetitis venae sectionibus, aliisque re- mediis derivantibus ac antiphlogisticis mitigata fuit, verum mansit fceda cica- trix, & crassa opacitas in tota cornea. A 44 De Pulsatilla nigricante. A variis varia collyria, aliaque reme- dia applicabantur ; morbus autem sem- per in pejus mutabatur. Nunc per tres menses usus est pul- vere A., & vix amplius cicatricis mini- mum vestigium superest, cornea tota optime pellucet, & oculus objecta per- fecte videt. EXPERIMENTUM XXVII. Puer, 8. annorum, ante binos annos variolis laboravit, & his superatis orie- batur inflammatio in utroque oculo, qua disparente remansit opacitas in tota cor- nea oculi dextri, & sensim formabatur pannus crassus; in oculo sinistro obser- vatae sunt variae maculae albae, quae visum turbarunt. Spatio binorum & dimidii mensium usu pulveris A., oculi ambo perfecte sunt curati. Ex- De Pulsatilla nigricante. 45 experimentum xxviii. Juvenis, 22. annorum, a septem mensibus gerit testiculum dextrum indu- ; ratum, & magnum ex gonorrhaea, re- mediis adstringentibus suppressa. Tentavimus pulverem A., & spatio binorum mensium testiculus ad statum naturalem fuit redactus. EXPERIMENTUM XXIX. In viro, 31. annorum, eodem mor- bo laborante eundem pulverem adhibui- mus longo tempore, verum nulla fiebat mutatio. EXPERIMENTUM XXX. Vir, 24. annorum, pertaesus diutur- nae gonorrhaeae, parat sibi injectiones ex remediis saturninis, quibus virulentae ma- 'teriei fluxus sistitur; & urinae ardor cessat Se tunc cito curatum gloriabatur, & gaudebat; verum post duodecim circiter dies 46 De Pulsatilla nigricante. dies dolorem obtusum sensit in testiculo dextro, & eum tangendo observat esse multo majorem, & durum valde. Sumsit remedia purgantia & mercu- rialia, sed sine effectu per alquot septi- manas. Tandem me accessit, & re bene exa- minata adhibui pulverem A., ex cujus usu spatio binorum mensium magnum le- vamen sensit; etenim testiculus mollis f actus est, & multo minor; & tunc se jam curatum putavit, & ab ulteriori usu remedii abstinuit. Contigit postea, ut iterum praeter causam sibi cognitam idem testiculus valde intumuerit, durus admodum evaserit, & cceperit multum dolere. Unde anxius rediit, & novam pulve- ris dosim efflagitavit. Dedi tunc purgans ex granis XL. Ja- lap. & totidem granis cremoris tartari; & altero die praebui grana XX. pulveris B. ma- De Pulsatilla nigricante. 47 mane, eandem dosin iteravi ad meridiem, & vesperi. Hac ratione, diligenter continuando, spatio novem septimanarum perfecte con- valuit asger; testiculus naturalem magni- tudinem, mollitiem, & figuram iterum obtinuit. EXPERIMENTUM XXXI. Homo, 29. annorum, pannum eras- sum jam a 23. annis habet in oculo sinistro supra totam corneam transparentem. Hoc malum ex variolis confluentibus originem derivavit. Pulvis B. intra paucos dies manife- stam induxit mutationem; p annus hinc inde tenuior & transparens fiebat, & aeger coepit lumen bene distinguere. Mensis spatio p annus evanuit, & re- linquebatur solummodo in latere sinistro levis nubecula; quae sensim quoque dif- flatur. Sta- 48 De Pulsatilla nigricante. Statim in principio dedi huic aegro ter quotidie scrupulum unum pulveris B., nee amplius dosim auxi. EXPERIMENTUM XXXII. Foemina, 50. annorum, ab aliquot annis laborat in oculo dextro amaurosi, & in sinistro habet cataractam. Nunc in tertium mensem utitur pul- vere A. & iris in oculo dextro fit mobi- lis, & cataracta jam videtur multo tenuior, sed aegra nullam adhuc lucem percipit. EXERIMENTUM XXXIII. Vir, 40. annorum, ex morbo acuto, gravi admodum, visum in utroque oculo sensim amisit; in dextro orta est amauro- sis, & in sinistro glaucoma. Per aliquot annos utebatur variis re- mediis, sed a nullo sensit in oculis le- vamen. Per binos menses nunc sumit pulve- rem A., & glaucoma minuitur, iris in ocu- De Pulsatilla nigricante. 49 oculo amaurotico mobilis fit, & aeger can- delam vespertino tempore lucentem di- stinguit. EXERIMENTUM XXXIV. Puer, 6. annorum, oculo dextro fere nihil videt, quoniam is totus est opacus, & turbidus ex morbo varioloso, quern biennio abhinc passus est. Sumsit nunc pulverem A. per binos & dimidium menses, & oculus est serenus, & visus bonus. EXERIMENTUM XXXV. Puella, 9. annorum, ad depellendam oculi dextri inflammationem applicuit col- lyrium ex aqua rosarum, & vitriolo al- bo; valde tunc doluit oculus, & aucta fuit inflammatio. Venae sectionibus & remediis antiphlo- gisticis alvum ducentibus opus erat, ut suppuratio impediretur. D Ces- 50 De Pulsatilla nigricante. Cessit tandem inflammatio, sed man- sit opacitas in tota cornea, & oculus erat adeo sensilis, ut nee minimum lumen fer- re potuerit. Dedi ter de die grana X. pulveris A., & altero statim die oculus, qui antea erat ftotus siccus & aridus, coepit multum plorare. Spatio octidui puella eodem oculo po- tuit lumen sat commode ferre. Finito mensis spatio oculus bonus fuit; nee necesse erat augere remedii dosim, quoniam has cito & bene perficiebatur cu ratio. EXPERIMENTUM XXXVI. Juvenis, 13, annorum, ad angulum externum oculi dextri habet tumorem ex rubro lividum a medio anno, & tota ejus- dem oculi cornea est opaca, & obducta crassa albugine. Suasi ut ter de die sumeret grana X. pulveris A., qui in principio magnos do- lores excitavit in oculo et tumore. Spa- De Pulsatilla nigricante. 51 Spatio octidui ex tumore fiebat ab- scessus, qui sponte rumpebatur, & pus bonum, copiosum effluxit. Curavi dein ruptum tumorem tegi em- plastro diach. simplici, & jussi, ut conti- nuaret pulverem A. eadem dosi. Spatio unius mensis tumor totus dissi- patus est, & oculus naturalem pelluci- ditatem recuperavit. EXPERIMENTUM XXXVII. Puer, 10. annorum, ulcus sordidum & magnum habuit ad tibiam pedis dex- tri, collum & scapulam dextram serpigo antiqua occupavit. Sumsit ter de die vasculum infusi le- nioris Pulsatilla nigricantis, & eodem in- fuso eluit mane & vesperi ulcus, & dein lintea carpta eodem infuso madida ap- plicuit. Spatio binorum fere mensium non so- lum ulcus perfecte fuit curatum, sed etiam serpigo tota evanuit. D 2 Uri- 52 De Pulsatilla nigricante. Urina ex usu hujus infusi copiose eli- ciebatur. EXPERIMENTUM XXXVIII. Vir, 46. annorum, in oculo dextro propter cataractam admodum densam nil videt. Sumsit nunc per quinque septimanas pulverem B., & cataracta videtur te- nuior, & aeger, dum candela incensa fer- tur in cubile, lucis splendorem percipit. Magnos semper ex assumpto remedio dolores sentit in oculo afrecto. EXPERIMENTUM XXXIX. Vetula, 65. annorum, ultra viginti annos oculo sinistra prorsus nil videt; erat enim is totus ex ophthalmia inflam- matoria destructus, & habebat figuram, molemque praeternaturalem. Sumsit per binos menses pulverem A., unde in principio dolor ingens in oculo oriebatur, post aliquot dies ccepit pus per De Pulsatilla nigricante. 53 per narem sinistram mungendo prodire, dein ex partibus internis palpebrarum, & earum margine copiosum pus protrudeba- tur; membranae crassae, albae, & varie- gati coloris, factae sunt tenuiores, moles oculi diminuta est, & aegra hoc oculo po- test nunc objecta distinguere. EXPERIMENTUM XL. Vir, 62. annorum, in oculo sinistra jam ultra septem annos habet cataractam, & nihil videt, oculus dexter ita quoque debilitatus & sensim turbidus factus est, ut miser nee labores suos amplius perfi- cere, nee solus in platea ambulare po- tuerit. Sumsit ter quotidie grana X. pulveris B., & jam solus per plateas incedit libere, & labores suos, qui oculum exactum re- quirunt, peragit, & in oculo sinistra can- delae lucentis splendorem percipit. D 3 In 54 De Pulsatilla nigricante. In hoc aegro promptiffimum remedii effectum observavi; nam hae mutationes spatio duodecim dierum contigerunt. Sunt adhuc numerosissimi aegri, qui ex- tracto Pulsatilla nigricantis utuntur, & in pluribus bonum effectum jam experior. Vir, 35. annorum, pertinacissima me- lancholia laborans, & totus macilentus sumsit pulverem B. & inde intra paucum tempus reficiebatur, perversa? mentis ideae disparuerunt, rediit robur, & sa- nitas. Unde putabam: idem forsan medica- mentum profuturum Epilepticis aut Ma- niacis. Rogavi propterea Dominum Faucken & Dominum Rechberger, ut in suo No- socomio ad S. Marcum, ubi tot homines similibus malis affecti decumbunt, expe- rimenta instituerent. Verum nee in morbo epileptico, nee in mania ullum ex hoc remedio effectum observarunt. Au- De Pulsatilla nigricante. 55 Augebatur dosis, donee epileptici drachmas duas, & aliqui maniaci drach- mas tres pulveris B. per diem assumsissent; nee ullo modo inde afficiebantur. COROLLLARIA. I.) Pulsatilla nigricans est remedium in- nocuum & efficax. 2.) iEgri videntur facilius ferre extra- ctum hujus plantae, quam ejus aquam destillatam, quoniam haec majori dosi data aliquibus conatum vomendi, & nauseam excitavit. 3.) Nihilominus sunt aegri, qui hanc aquam sine omni molestia assumunt, & iis subinde prodest in vehementissi- mis artuum doloribus nocturnis, in tophis venereis &c. profuit quoque quibusdam paralyticis. 4.) Extractum Pulsatilla nigricantis sol- vit potenter, nil tamen in corpore turbat. D 4 5- Plu- 10 56 De Pulsatilla nigricante. 5.) Pluribus movet urinam copiose. 6.) Quibus tormina ventris exitat, & dein leviorem diarrhasam, his saluta- re plerumque est. 7.) In quibusdam chronicis oculorum af- fectibus videtur maxime convenire, & vix non specifice in oculos agere. 8.) iBonum est: si aegri sentiant inde in oculis dolorem. 9.) Amaurosim subinde curat, quando- que diminuit cataractam; pannos au- tem, ungues, & albugines frequenter dissipat, neque opus est ullo remedio externo. 10.) Infusum Pulsatilla nigricantis tuto quoque datur interne, applicaturque externe in foedis ulceribus, in carie, & serpigine. 11.) Quibusdam fceminis fluxum men- struum, prasternaturaliter suppressum, Pulsatilla nigricans iterum excitat, & redigit in ordinem. APPEN- De Pulsatilla nigricante. 57 Appendix. Biennio abhinc edidi libellum de usu interno & externo herbae Flammulce Jo- vis, & multis experimentis comprobavi: Flammulam Jovis efficacissimum quando- que Remedium esse in pertinacissimis & diuturnis capitis doloribus, in ossium do- loribus nocturnis, in cachexia venerea, in scabie, herpete, in ulceribus ichoro- sis, fungosis, cancrosis, in carie os- sium &c. Iterata experimenta usu ejusdem her- bae & a me & aliis multis Medicis institu- ta eundem iterum effectum, & eandem efficaciam confirmant & adtestantur. Foeminae plures, summa & tristissima melancholia laborantes, infuso Flammules Jovis integre restitutae sunt. Ferdinandus Leber chirurgiae Professor cancrum exulceratum mammae, qui nee cicuta nee aliis medicamentis mitigari po- rerat, sola Flammula Jovis radicitus percu- D 5 ra- 58 De Pulsatilla nigricante. ravit publice coram suis discipulis & qui- busdam Medicis. De usu & utilitate Cicutce ulterius dis- serere superfluum arbitror; quum novi viros cordatos, & bonos Medicos illam ea, qua par est, aequitate respicere, illam- que asgris suis optato cum successu persae- pe adhibere. Extractum Aconiti flore coeruleo, seu Extractum Napelli nova experimenta sem- per magis magisque commendant; & est sane! egregium medicamentum, quod parva dosi multum praestat. Prodest frequentissime in malis vene- reis, ubi laudata alia remedia incassum adhibentur. Tollit quandoque exostoses venereas, & articulos rigidos reddit mobiles. Levavit saepius Podagram, Arthriti- dem, & Rheumatismos pertinacissimos. Dedi hoc extractum in similibus mor- bis, etiamsi febris adfuisset valida; sed tunc adjunxi debitam nitri quantitatem. Et De Pulsatilla nigricante. 59 Et observavi hac methodo aliquoties vehementissimos dolores fuisse intra ali- quot horas penitus dissipatos, qui per multos dies copiosissimis aliis medicamen- tis nee leniri poterant. Plerumque sudor largus sequebatur. iEgri ferunt hujus extracti grana duo, tria, quatuor, quinque &c. nycthemeri spatio, dosibus divisis. Oxymel ex recenti & succulento Col- chici autumnalis Bulbo paratum, plures ite- rum gravi hydrope, vel & asthmate glu- tinoso pessime affectos curavit pellendo urinam, aut promovendo sputa copiosa. Si hoc oxymel ex Bulbo arido vel fari- noso conficiatur, tunc caret omni efficacia. Extractum cicutce mixtum cum oxy- melli colchico in hydrope, a viscerum ob- structionibus orto, saepe mira praestat. Hyosciami Extractum spasmos & con- vulsiones frequenter compescit; juvat quandoque in morbo epileptico, in ma- nia, & furore. His- 60 De Pulsatilla nigricante. Hisce diebus vidi sacerdotem optime valentem, & fungentem munere honori- fico, ad quod perfecta mentis sanitas re- quiritur, qui ante binos annos mania la- bo ravit. Similes casus existunt plures. Fcemina, 38. annorum, per tres inte- gros annos singulo mense bis vexabatur paroxysmo gravissimo epileptico, cura- ta solo hyosciamo, jam ultra annum optime se habet, hilaris est & libera ab omni malo. Hyosciamus tusses molestissimas phthi- sicorum quandoque longe melius & citius mitigat, quam ipsum opium. Parva dosi subinde optimo cum suc- cessu exhibui extractum Hyosciami in con- vulsionibus infantum, ortis a terrore. Hoc extractum recta methodo datum asgris nunquam nocet, & confert saepe. Miror propterea magnae famae Me- dicum in ultimo suo tractatu extractum Hyosciami aut inutile pronunciare aut no- De Pulsatilla nigricante. 6i xium; licet id propria experientia son observaverit, sed audierit solummodo ex aliorum relatis. Ego certus sum, quod doctissimus ille Vir, quem vere veneror, aliam de Hyosciamo sententiam confiteretur, si so- lita sua prudentia ejus extractum in aegris suis tentaret. .',',