L b= J Gornell University Library Ithaca, New York FROM J. S. Navy Department a SPE CIAL ie juMBER UNITED STATES NAVAL | MEDICAL BULLETIN | » PU BLISHED FOR THE- - INFORMATION. OF THE MEDICAL DEPARTMENT OF THE SERVICE. ISSUED BY THE: ‘BUREAU OF MEDICINE AND SURGERY: “NAVY DEPARTMENT | ~' DIVISION OF PUBLICATIONS REPORT. MEDICAL AND SURGICAL DEVELOPMENTS « oF THE WAR WILLIAM SEAMAN BAINBRIDGE / LIEUTENANT COMMANDER, MEDICAL CORPS UNITED STATES NAVAL RESERVE FORCE ; WASHINGTON GOVERNMENT PRINTING OFFICE " , JANUARY, 1919 SPECIAL NUMBER UNITED STATES NAVAL MEDICAL BULLETIN PUBLISHED FOR THE INFORMATION OF THE: MEDICAL ‘DEPARTMENT OF THE SERVICE ISSUED BY THE BUREAU OF MEDICINE AND SURGERY NAVY DEPARTMENT DIVISION OF PUBLICATIONS REPORT MEDICAL AND SURGICAL DEVELOPMENTS oF THE WAR BY WILLIAM SEAMAN BAINBRIDGE LIEUTENANT COMMANDER, MEDICAL CORPS UNITED STATES NAVAL RESERVE FORCE WASHINGTON GOVERNMENT PRINTING OFFICE JANUARY, 1919 i os RD. vy Be * A 456463 e ‘Navy DeparrMENT, Washington, March 20, 1907. This Unrrep Srares Navan Mepican Burierrn is published - direction of the department for the timely information of the Medi- cal and Hospital Corps of the Navy. Truman H. Newserry, Acting Secretary. NOTE. Owing to the exhaustion of certain numbers of the ButLerin and the frequent demands from libraries, etc., for copies to complete their files, the return of any of the following issues will be greatly appreciated : Volume X, No. 1, January, 1916. Volume XI, No. 1, January, 1917. Volume XI, No. 3, July, 1917. Volume XI, No. 4, October, 1917. Volume VII, No. 2, April, 1913. SUBSCRIPTION PRICE OF THE BULLETIN. Subscriptions should be sent to Superintendent of Documents, Government Printing Office, Washington, D. C. Yearly subscription, ‘peginning January 1, $1; for foreign subscription add 25 cents for postage. ‘ : § Single numbers, domestic 25 cents; foreign, 31 cents, which includes for- eign postage. , : : Exchange of publications will be extended to medical and scientific organiza- tions, societies, laboratories, and journals. Communications on this subject should be addressed to the Surgeon General, United States Navy. Washing- ton, D. C. i CONTENTS. REPORT: TREATMENT OF WAR WOUNDS BY THE ALILIES............¢...02.-02--.- Wound suture; primary, delayed primary, secondary................. Carrel-Dakin treatment.............0.0 0000000 ce cece cece eee ceeneeee Trephined cases........... joisid ee ald one lercia tag aclordenery amt e elwale ATH PU tations acto. cs tt ee cciehne $a y Secede cane eh is poe a cauis o cc Plastic and oval surgery......-...-.-02. 2-2. s eee cece eee ee eee eee eens Trenco Frver......-. #g)e eqaalesandass so 6 as eeatemeeeew e ¥ Fee saGGe dee s ook Care OF WOUNDED FROM Firine LINE To CONVALESCENT OAMP....... Surgery of the forward area, and transportation of the wounded....... Special notes on some of the hospitals visited........................ Military orthopedic hospitals...........2..2..2-.2..02 0020 e cece eee Convalescent camps...|..-..-- 2022-2 2--e eee eee eee eee nee eeees REEDUCATION FOR THE DISABLED..........--..2-0--2-20--2-0eec ec eeeee Functional ses scsxsseenag sss va teetwaness + 642 sejtaccudyheoss scared Vocationshees: <2 xsicsscsieu ed Sakiiganivs oy bb ae egaene odo vane Inter-allied conferences of surgeons..................--020.--es eee ee AUXITIARY NORGHS asc sccomesccceeun es aueaiaeiieds sch oiseegne eS ees SS MIGCELUANEOUS wos songs sore giun c's 64.9 Hee sOeNes pe oes ae eee Yew ees se Provisional legs sess vec asroeewaw «'s 2 x's) etwas «on 5 cleinbreseiiaueeale se Plan for surgical evacuation hospital formation.............-....-...- Proposed organization of educational service in war surgery........... Special points with regard to disposal of U.S. A. casualties. ......... Plan for surgical sanitary formations.............-.-.-------2-+--++-- " RECOMMENDATIONS..........000000ec cece cece eee eee eee eee e ee eeeeee TecuNnicaL Instructions ror IMPENDING MILITARY ACTIVITIES.......- Rerort oF TECHNICAL ADVISORY COUNCIL...........02-.-000e eee eee eeee Base HospitalizaATION AND Sure@icaAL MEASURES FOR AN ATTACKING PREFACE. 4 The"publication and issue of a quarterly bulletin by the Bureau of Medicine and Surgery contemplates the timely distribution of such information as is deemed of value to the personnel of the Medical Department of the Navy in the performance of their duties, with the ultimate object that they may continue to advance in proficiency in respect to all of their responsibilities, It is proposed that the Navan Mepican Buurerin shall embody matters relating to hygiene, tropical and preventive medicine, pa- thology, laboratory suggestions, chemistry and pharmacy, advanced therapeutics, surgery, dentistry, medical department organization for battle, and all other matters of more or less professional interest and importance under the conditions peculiar to the service and pertain- ing to the physical welfare of the naval personnel. It is believed that the corps as a whole should profit, to the good of the service, out of the experience and observations of the individual. There are many excellent special reports and notes beyond the scope of my annual report being sent in from stations and ships, and by communicating the information they contain (either in their entirety or in part as extracts) throughout the service, not only will they be employed to some purpose as merited, but all medical officers will thus be brought into closer professional intercourse and be offered a means to keep abreast of the times. Reviews of advances in medical. sciences of special professional interest to the service, as published in foreign and home journals, will be given particular attention. While certain medical officers will regularly contribute to this work, it is urged that all others cooperate by submitting such abstracts from the literature as they may at any time deem appropriate. , Information received from all sources will be used, and the bureau extends an invitation to all officers to prepare and forward, with a ~ view to publication, contributions on subjects relating to the pro- fession in any of its allied branches. But it is to be understood that the bureau does not necessarily undertake to indorse all views and opinions expressed in these pages. W. C. Braistep, Surgeon General United States Navy. v FOREWORD. This report comprises observations on the western front and in England during December, 1917, and the first six months of 1918, miade pursuant to the instructions of the Surgeon General, United States Navy. For purposes of comparison, there have been added certain data obtained while in Germany during the autumn of 1915. In making the survey, the following objects were kept constantly in mind: 1. To record the surgical lessons of the present war based on the experience of our allies. 2. To secure anything likely to be of value to the United States Naval Medical School, Washington, D. C., or helpful in the prepara- tion of medical men and hospital corpsmen for active service. The United States Navy is justly proud of its efficiency and fore- sighted policy of preparedness. Accordingly, it desires to have its medical corps fully abreast of the Army in learning the lessons being taught by this world war. The medical service of the Navy has not only the usual duty of caring for the incidental casualties in the Navy and of being constantly ready for sea warfare on a large scale, but is responsible for the marines fighting on land, maintains its own base hospitals abroad, some of which at times are ‘used exclusively for the Army wounded, sends forward operating teams to aid in times of crisis, and is entrusted with the care of the sick and wounded from all branches of the Army as well as of the Navy, on their way home. Our troop transports going over are ambulance transports on the return trip. “As ‘the men return to this side, the great questions of aftercare, restoration of function, plastic surgery, reeducation, and the like become matters of great importance. While the Army with its enormous numbers is most deeply concerned, it is just as vital from the standpoint of the needs of the bndlistduall that the naval per- sonnel should be thoroughly equipped to deal with the same problems, although they may be called upon to care for fewer cases. In harmony with the policy of making ready, and in order to supplement the individual reports which from time to time have come from various sources to the Bureau of Medicine and Surgery, Surgeon A. M. Fauntleroy, United States Navy, was sent abroad in VII VIIT rGREWORD. 1915 and upon his return made a report on the medico-military aspects of the European war. His observations have proved of much value and have helped to a larger knowledge of many matters connected with the war on the part of the medical officers of the Navy, as well as of surgeons in civil life. As indicated above, a somewhat different field is covered in the present survey. In writing a report of this kind, where the material gathered is so exhaustive and illuminating, there is a strong temptation to go ‘into detail. An effort has been made to combat this temptation and to cover only such points as seem to have a practical bearing on the objects for which the survey was made. Every source of information which could be reached in the time at my disposal has been utilized. The experiences of the British, the French, the Belgians, and of those American surgeons who were in active war service with our allies before we entered the conflict, were unreservedly placed at my disposal. To all who so materially as- sisted me I am most grateful. In both of my preliminary reports (April 27, 1918, and July ‘10, 1918) to the Bureau of Medicine and Surgery I mentioned some of those who aided me with advice and with information. Here and there in the text which follows will be found the names of some who furnished special data or contributed material for exhibits to accom- pany this report. If space permitted there are others to whom a special word of thanks should be given for their cordial cooporation and assistance. Particularly am I indebted to the American Red Cross, through Major J. H. Perkins, Major Alexander Lambert, Mr. Homer Folks, and their staffs; to the British. Red Cross, through Colonel Sir Arthur Lawley, Q. C. S. I.; to the French authorities, through M. Jean de Piessac, Prof. Theodore Tuffier, General Gou- rard, and Major Alexis Carrel; to the British Army, through Lieu- tenant General Sir Beauvon de Lisle and many others, for the many opportunities and hospitalities extended to me at the request of Director General Thomas H. Goodwin; to the Colony of Strangers, through M. Lawrence V. Binnet and Dr. Ernest H. Lines. Without their aid, and that of Commander W. R. Sayles, United States Navy, late naval attaché at Paris; Dr. Herbert Adams Gibbons, of the American Committee on Public Information, and General A. E. Bradley, until recently chief of the Medical Corps, American Expe- ditionary Force, this survey could not have been made. . | - W. S. B. New York, September 14, 1918. REPORT ON MEDICAL AND SURGICAL DEVELOPMENTS OF THE WAR. TREATMENT OF WAR WOUNDS BY THE ALLIES. In the many hospitals and casualty clearing stations visited, the method of treating war wounds varied greatly. There were those who believed in the use of the strongest antiseptics, as at the Grand Palais, where phenolization was employed, while others favored in- cising freely with drainage and practically no antiseptics. More and more, the two extremes are being emphasized; on the one hand, the Carrel treatment with its scientific laboratory control and systematic use of strong antiseptic solutions, and on the other, débridement and immediate closure. . : Late in September, 1915, after having spent considerable time in the hospitals of both the German and French armies, Prof. Kocher, of Berne, said to me: “The great lesson of the war so far is, back to antiseptic surgery. Asepsis is not enough.” Tm contrast with this, three years later (in June, 1918) Major A. L. Lockwood, D. S. O., who has had one of the largest experiences im acute war surgery in the present conflict, said when I was at casualty clearing station No. 36, behind the British front: “One of the greatest lessons of this war is that aseptic surgery and not anti- septic surgery should be practiced, the former in all cases, the latter associated with it in selected cases.” Between the two extremes of the Carrel-Dakin treatment and primary suture, both of which are described in detail hereinafter. there are many other methods and agents employed with more or less satisfactory results. These are also taken up somewhat briefly. Their classification is arbitrary for there is overlapping all along the line. . After going from hospital to hospital and station to station and hearing éach of these many methods acclaimed or criticized, it be- comes convincingly apparent that the obtaining of satisfactory re- sults depends far more upon the surgeon himself than upon the agent which he employs. The lesson to be learned from all this diversity of opinion is that those who are to be given charge of this surgical work should have first, a thorough knowledge of surgery, second, sufficient 1 2 I. WOUND SUTURE. experience to give them an adequate technique, and third, the neces- sary judgment to select and employ such of these methods or agents as seem best for the particular case at the given time. From the purely therapeutic viewpoint, the surgery of wounds in the present war may be grouped under fairly approximate chrono- logical headings, as follows: ; 1. The period of ordinary antiseptic agents; second half of 1914 and first half of 1915. ; 2. The period of wound drainage combined with antiseptics, 1915. 3. Introduction of hypochlorites; later in 1915. 4, Evolution of the Carrel’ technique of intermittent wound in- stillation; early in 1916. ; 5. Ascendency of Bipp method; 1916. 6. Period of approximately equal use of the Morison and Carrel methods; 1916-17. 7. Prominence of flavine and colored wound pastes, such as bril- lant green; 1917. 8. Progressive general adoption of wound-excision method (which had its beginnings early in 1916) ; late in 1917. 9. Period of primary wound suture, immediate or delayed; - 1917-18. . 10. Period of attempted selection, adaptation and standardization; late 1918. I, WOUND SUTURE. In the recent remarkable advance of the science and art of surgery, with its exacting demands upon the time and energy of modern operators, its modest beginnings are sometimes overlooked, but a rich vintage is in store for the investigator of medical records of the past. After visits to the front and observing much of primary and delayed suture, I determined to secure the memoirs of Paré and the life of Larrey, with a view to learning if any of the modern war wound treatments was foreshadowed by those two great surgeons who lived so much in advance of their times, and who, many years ago, fought over northern France and southern Flanders much as we are now doing. Neither in Paris nor London was I successful. Finally, by advertising, both volumes were obtained from the North of England. There, in the last of the sixteenth century was described immediate closure; and in the days of Napoleon, molded splints and early primary amputation, much as we know them to-day, except for the phraseology of the time. The pioneer in the proper treatment of gunshot wounds, and per- haps the forerunner of ultramodern methods of treating fractures and other war wounds, was Ambroise Paré, the father of French I. WOUND SUTURE. 3 surgery, who was enabled to add the surgical observations of many years of. warfare to his early experience as an army surgeon in the Piedmont campaign.. Later on he became the premier chirurgien of the French kings, Charles IX and Henry III. The first English translation of his works appeared in London in 1578. In Book IX of his “ Chirurgery ” he devoted to wound suture a chapter enriched by illustrations showing “ The figures of pipes with fenestels in them, and needles fit for sutures,” and introduces his subject as follows: When wounds are made alongst the thighs, legs, and arms, they may easily want sutures, because the solution of continuity is easily restored by ligatures, but when they are made overthwart, they require a suture, because the flesh and all such like parts being cut are drawn towards the sound parts; whereby it comes to pass that they part the further each from other: wherefore that they may be jointed and so kept, they must be sewed, and if the wound be deep you oust take up much flesh with your needle; for if you only take hold of the upper part, the wound is only superficially healed; but the matter shut up, and gathered together in the bottom of the wound, will cause abscesses and hollow ulcers; wherefore now we must treat of making sutures. As to the first dressings to be used in “ wounds made by gunshot, other fiery engines, and all sorts of weapons, after the strange bodies are plucked or drawn out of the wound,” Paré laid stress on the im- portance of tight binding up and rolling the part; “for it doth not a little conduce to the cure to bind it so fitly up as it may be without pain.” The presence of Paré in Metz during the attack of Charles V, was regarded as a providential dispensation, for the garrisons saw, to their dismay, that death followed on practically all wounds. Modern methods of war-wound treatment are distinctly fore- shadowed in the writing of some of Paré’s pupils, for example in the little known, but most interesting Sclopotarie of Josephus Querce- tanus, Phisition, or his booke containing the cure of wounds received by shot of gunne or such like engines of warre (published in English in London in 1590). In the third chapter, speaking of wounds in which the benes of the arms and legs are broken, he differs from some of his contemporaries who favor open-wound treatment, in that, in his judgment, he thinks it best “that the bones by and by before inflammation be engendered be brought in their seat and natural form, with as little pain as may be to the patient, and then to use such medicines as are profitable to both intentions—that is, for the wound and fracture. Moreover, you must see that the wounded part be rightly placed, and if need be, rolled in a plate of lead, bowed to the fashion of a leg or an arm, or else with sodden leather fastened together with buckles, whereby the bones which were broken, may the surer be holden together, which ought not (as little as may be) be shaken and moved, until he is cured, and the bands loosed * * * by which only I have seen fractures cured, the bones being rightly placed,” ete. , 4 I, WOUND SUTURE. The originator of much modern military surgery was Baron Lar- rey, surgeon in chief of the first Napoleon’s Grande Armée, who has been called the father of military surgery. It is interesting to note that he was nominated surgeon of the Royal Navy in 1787, and took part in a cruising expedition in North American waters. Although no mention of immediate closure of war wounds occurs in his writ- ings, a surgical memoir read by him at the Royal Academy of Medi- cine in Paris on February 19, 1819, describes at length an extensive operation for the removal of a large glandular mass from the neck of a man 40 years of age, the edges of whose wound were at once drawn together and united by a series of sutures. All the stitches held well, and the large wound healed promptly, the patient being cured on ‘the thirty-first day after the operation and leaving for his home in excellent condition on the forty-first day. Practically the identical words which, in the present war have been pronounced in connection with the progressive danger of infection of all war wounds, were spoken a century ago by Larrey, in comment- ing upon the utility of immediate amputations: An hour’s delay is often responsible for the death of the patient. This is doubly inter- esting and remarkable in view of the fact that a large part of Lar- _ rey’s work was done on Flemish soil, made familiar to us by .the events of the world war; for we read of his being sent to Louvain and Brussels, or of his visiting the military hospitals of Great Britain, like contemporaneous army surgeons. The brilliant career of Baron Larrey brings us close to the present day, when war sur- gery has perhaps reached its zenith, the operator standing at the head of the medical profession just as the man in uniform represents the dominating factor in both the Eastern and the Western Hemispheres. IMMEDIATE, DELAYED, AND SECONDARY SUTURE. Under favorable conditions, primary union by immediate or de- layed suture of war wounds which have been operated upon and properly purified, is now the last word in this branch of surgery. Experience in the world war has taught entirely new lessons to the surgeons who found themselves confronted with unprecedented con- ditions both in regard to the masses and classes of war wounds they were expected to handle. Perhaps the most important lesson of all, with the closest bearing on wound treatment in general, consists in the recognition of the fact that antiseptics are inefficient without the most careful and thorough mechanical purification of the wound, in- cluding the complete removal of all dead or nonviable tissue. Cer- tain phases of antiseptic wound treatment are passed in review in “An Address on Primary Suture of Wounds at the Front in France,” by Surgeon General Sir Anthony Bowlby, delivered at a meeting of the Royal Society of Medicine on February 13, 1918, and I. WOUND SUTURE. 5 published in the British Medical Journal, Volume I, March 28, 1918. page 333. Strong antiseptics, such as were used early in the war, in the ex- pectation of arresting sepsis, were foredoomed to failure, as a re- sult of the unprecedented bacterial contamination of war wounds sustained in the germ-laden battle fields of Flanders. The prompt discarding of these antiseptics involved the abandonment of primary union by suture of war wounds, followed as it was at first by dis- couraging results. On the other hand, the opposite method of leay- ing the wounds wide open and maintaining a free discharge of the wound secretions, in its turn proved disappointing. A successful outcome was found to depend upon the performance of excision be- fore the infectious bacteria have had time to penetrate far into the depth or surroundings of the wound. The period which has elapsed since the infliction of the wound thus becomes a factor of great prog- nostic importance. In a general way, and with certain reservations, “delay means danger” (Bowlby). According to the report of Duval, at the allied surgical conference in November, 1917, 80 per cent oe the lightly woinded cases, without fracture, were successfully su- tured within 8 to 12 hours after the injury. By “delayed primary suture” is meant.a wound suture which is applied at the end of a day or two after the infliction of the wound. Even after three or four days’ delay, the wound may be sutured with the same favorable results as obtained by immediate suture. The experience of French operators, who are the pioneers in this field, shows that such delay, of 48 or more hours, is advantageous rather than otherwise in a large number of cases. The observations at the front on the part.of Sir Anthony Bowlby are in conformity with this experience. According to him, “no definite rule can be laid down as to the lapse of time after which suture should not be done, ‘but the sooner the wound can be operated upon, the greater is the probability of success. It can be sutured later.” Asa matter of fact, it is not advisable to close at once war wounds involving extensive. lacerations, or:complicated fracture cases, for all oozing from the wound must have ceased before a successful suture can be applied. Circumstances alter cases, and the best treatment for a given wound rests with the surgeon in charge. Doubtful wounds are preferably left open, after excision of all dead or dying tissue, until conditions permit of a decision. It goes without saying that the ever present contingencies of infection and suppuration are materially lessened by the early performance of complete wound closure. Scrupulous asepsis is the imperative condition of primary wound suture, immediate or delayed. While thorough in the removal of all hopelessly damaged tissue, the excision should: be as conservative and restricted as possible. No part of the wounded region must be 6 I. WOUND SUTURE. neglected or slighted, the greatest care being especially required in all deep wounds and in open or compound fractures. The perform- ance of primary suture transforms the latter into simple or closed fractures, and thereby greatly lessens not only the danger of sepsis but also the soldiers’ enforced rest in bed or in hospital. Certain limitations of primary suture of war wounds, emphasized by Doval, are that the procedure can not be used in emergencies, and also that its performance is not advisable unless the patient can be kept in the hospital for at least a fortnight, under the care of the same surgeon. -There are certain cases of relatively old wounds, not yet operated upon and clinically noninfected, or very mildly infected, capable of being closed by suture, which under these conditions must be de- scribed as delayed primary suture, for the reason that the operation is performed after the first 12 hours, namely, after the usual stage of bacteriological latency of war wounds. Such sutures differ: es- sentially from the purposely delayed sutures in cases where the: cleansed and surgically sterilized wound is left open and covered . with aseptic dressings in the first aid stations, being united by sutures later on at a greater distance from the front. According to Chalier (Le Progrés Médical, No. 27, 1918), this delay can often be ° advantageously utilized, for instance, for the radiological localiza- tion of a projectile, the removal of which is essential to the success of a complete operation terminated by wound suture. The desirability of extending the benefit of primary suture to all wounded soldiers, in time of attack, provided that operative: and hospital facilities permit, is emphasized by recent French writers (such as Marquis, Descazals, Luquet, and Morlot; Bull. et Mém. d. 1. Soc. de Chir. de Paris, 43, 2, 1917, p. 2281). In their experience, primary suture proved apparently most advantageous in wounds of the joints, where very accurate union was obtained; the method at the. time of the report had been utilized in nearly 450 cases, including | wounds of the bones, joints, and soft parts. Wounds of the skull, the thorax, and the abdomen were likewise sutured with favorable results. The mortality for all suture cases amounted to 21 deaths or 4.7 per cent. That primary suture is at present the rational and as it were the obligatory treatment for war wounds is the declaration of Gross Tissier, Houdard, Di Chiara, and Grimault (ibid.). From being exceptional, primary wound suture has become a common procedure largely through the work of Tissier, who first showed that all war wounds which are not infected by the streptococcus will heal after - suitable surgical treatment followed by the performance of primary suture. I. WOUND SUTURE. fe In the surgical automobile ambulance No. 12, which takes charge of the gravest injuries, such as extensive destruction of soft parts, long seton’ wounds, shattering and crushing of entire limbs, etc., 430 of 549 wounded men were sutured (78.8 per cent). Altogether, 759 sutures were applied in these 430 cases, and in 675 instances led to healing by first intention, which is equivalent to a successful out- come in 88.8 per cent of the cases. There were 209 fracture cases with a favorable result. .It is noteworthy that even conditions of such gravity as amputation of shattered extremities (22 cases), frac- tures of the vertebra, lesions of large blood vessels, deeply embedded projectiles in the cervical region, and other severe injuries of war are amenable to primary suture. The routine application of primary sutures is advocated by Gross and Tissier whenever the removal of the projectile and the excision of the necrotic tissue is practicable. Unless streptococci be detected in the early wound discharge, the sutures should not be disturbed. but the appearance of the streptococcus is.an indication for removal of the sutures and the performance of radical excision, in order to. check the putrefactive process. Secondary wound suture is recom- mended at the earliest possible date, where primary suture could not be applied. Only those war wounds are now left open in which there is-an association of anaerobic and streptococcic infection. The vast field of opportunity for the application of wound suture is illustrated | by figures such as the 880 cases of Potherat, in Delbet’s service, with 291 primary sutures, 209 of which proved successful, and 459 sec- ondary sutures. Perfect union after primary suture is reported by Picot in 25 of 30 cases of complicated diaphyseal fractures. — Barnsby (Revue Internationale de Médecine et de Chirurgie, No. 2. 1917, p. 26), in a series of primary sutures of soft-part wounds, ob- served healing by first intention in 160 of 172 cases. In the remain-. ing 12 cases, the stitches had to be removed, the wounds healing by second intention, without harm to the patient. The application of primary suture of war wounds is advocated by him in the 10 hours following the traumatism, in injuries of the following description: Simple articular wounds, or lesions of joints combined with slight bony lesions; wounds of soft parts (supra-aponeurotic) ; superficial glancing subaponeurotic wounds, the floor of which can be plainly seen after incising. All such wounds should be sutured, provided a reliable: asepsis and sufficient surgical cleansing can be secured. When the asepsis is uncertain, however, or when the wound is of. more than 20 hours” standing, especially when it is obviously in-- fected, or in serious injuries such as deep subaponeurotic wounds. large muscular seton wounds, extensive bone shattering (diaphysi< or epiphysis) and, finally, when there is any doubt, even in appa- 8 I. WOUND SUTURE. rently simple wounds, primary suture should be omitted, and the wound be treated according to Carrel’s method of intermittent instil-: lation, the proper time for the performance of delayed suture being determined by the daily bacteriological control of the wound. In justice to the method of primary suture, it should not be at- tempted in very large wounds with irregular tracks, where there is. extensive shattering of bone, or in injuries dating back more than | half a day or so (12 to 18-hours at most). In fracture cases, the im- portance of complete fixation and immobilization from the earliest possible moment can not be overestimated. The advent of primary wound suture, representing as it does a wonderful economy in time, money, and material, has brought about. a striking change in war surgery. Formerly, even after the deplor- able stage of overwhelming septic wound contamination was past, a long time was required for the repair and cicatrization of wounds which healed but slowly under laborious aseptic dressings. Before the application of at least secondary wound suture had become a reality, large numbers of wounded soldiers had to be evacuated before: their wounds were properly closed. The introduction of primary suture has greatly simplified modern wound treatment, which now consists essentially in passive supervision of the repair process, with- out dressings. The suture threads are removed on the tenth to fifteenth day. At the end of three weeks, the patient is evacuated to: the base hospital, or discharged on leave, according to the gravity of the condition. Credit must be given, especially in these days of precarious inter- allied communication, to War Medicine, published by the American Red Cross Society in France, for giving in the English language a re- view of the notable reports on primary wound suture published in the Bulletins et Mémoires de la Société de Chirurgie de Paris. The March number (1918) of this Red Cross bulletin also brings in full several papers on. this subject, by Engligh surgeons and bacteriolo- gists, indorsing the treatment of war wounds by primary and. es- pecially by delayed primary suture (the secondary suture of French writers). Colonel Gask emphasizes the nonoccurrence of deaths in a series so treated, though many of the cases were severe; no bad re-: sults were attributable to the early suture; the comfort and well-be- ing of the patients were noteworthy. In conclusion, it may be said that this procedure has come to stay, and that with the reservation of its three requirements—namely, an experienced operator, a convenient locality, and sufficient time—the adoption of primary wound suture will steadily extend. It is im- perative that the operator be one who knows how much tissue to re- move. If too little be removed death may result ;,if too much, a mutilation which is sometimes worse than death. 9 Aside from the benefit accruing to the severely wounded, primary wound suture involves the enormous advantage of restoring to ac- tivity, at the earliest possible moment, the hosts of men with minor wounds which, without this new technique, necessarily constituted a serious handicap for the armies in the past. In striking contrast with this prolonged disablement, Pierre Duval reports, after primary suture of flesh wounds, seven days’ leave and return to service in more than half the cases; and after delayed: primary suture, seven days’ leave and return to the regiment in 32 per cent of the cases; one month’s convalescence in 30 per cent of the cases, The overabundant clinica] material is being constantly replenished by the casualties of the war, as illustrated for example by the report of Lemaitre, in whose experience since July, 1915, when the use of antiseptics was definitely abandoned in favor of operative surgery, 2,664 (of 4,072) wounds were united by primary suture, 231 by de- layed primary suture, and 324 by secondary suture, for the most part between the seventh and fifteenth day after the infliction of. the in- jury, with a very small number of Poniuiness Med. Bull. (Red Cross), March Supplement, 1918. Although prior to the European war the closure of contaminated wounds by suture would have been regarded as foredoomed to fail- ure, and no such procedure at first entered the. minds of Army sur- geons, this method of wound treatment is not strictly speaking novel. nor is it incident to the current war. Far from being new, the com- bined surgical acts which culminate in primary wound suture. have been.in use for many years, and as stated before, the closure of gaping war wounds by sutures: with specially devised needles is described at length in the Chirurgery of Ambroise\Paré. Observation and.ex- perience have matured and improved the technique of the procedure, which at the present writing seems to have reached a stationary degree of perfection. ~The most extensive available statistics of primary suture of war words (2,587 cases) were, published in this year by Lemaitre of the V Army (Lyon Chirygical, Tome XV, 1918, p. 65) and show that 79 per cent of injuries can be treated successfully by primary closure, immediate or delayed, without excision of scar tissue. The statitstics comprise: Two thousand and thirty wounds of the soft parts; (1,060 very seri- ous, and 250 associated with bony, vascular, or nervous injuries) ; 87 injuries of large joints; 263 wounds with diaphyseal fractures; 110 wounds of hand and foot, with injured tendons, bones or joints; 40 injuries of the skull and brain; 7 injuries of the thorax. The method proved unsuccessful in only 0.84 per cent of cases. There were only four subsequent deaths, including three brain injuries and one penetrating wound of the thorax. Contraindications 10 II. CARREL METIIOD. are: Spreading infection, gas gangrene, a bad general condition, shock, shattered limbs necessitating amputation, association with vascular lesions of large blood-vessels. The suture method was gradually reached by Lemaitre in July, 1915, after successive phases of nonintervention, free exposure and surpical purification, complete excision of the entire wound track, fixation of microbes by means of iodine, and Carrel’s method of multiple instillation. The original technique of wound suture has been considerably improved in the last three years. Filiform drainage by means of silkworm gut, removed in three or four days, is recom. mended on the basis of favorable experience. Minute asepsis, and scrupulous hemostasis are indispensable, and radioscopy or operating on the radioscopic table, are helpful adjuncts) When performed by experienced surgeons, primary closure by suture constitutes the ideal modern treatment of war wounds. The method needs no defense, for it is its own best vindication. Lemaitre aptly calls it a worthy daughter of French surgery, destined to live and prosper. II. CARREL METHOD. CARREL-DAKIN TREATMENT. None of the procedures devised to meet the exigencies of the world war has aroused so great an amount of controversy in surgical circles as the Carrel-Dakin method of treating infected war wounds. Even among those who have used it there are bitter critics as well as earnest advocates. The result. is that a decision for or against its employment can hardly be arrived at by the surgeon without personal experience and observation of its results.’ After visiting scores of military hospitals abroad, and obtaining at first hand the views of the acknowledged leaders in war surgery, I have attempted to describe impartially the method and its appli- cation: It was first put to the test in the Compiégne Hospital, early in 1915, where the surgeons associated with Major Carrel became its ardent supporters. Although professional opinion is still divided regarding the value of wound treatment by continuous instillation of a special antiseptic fluid, the method has undoubtedly attained popular fame and favor. It has been accepted by the United States Government for its military medical services; and even behind the enemy’s lines there is a tendency to regard sodtigm hypochlorite as the turning point in the treatment of infected: war wounds and the answer to the puzzle of chemical wound disinfection. I have been so fortunate as to witness much of its development, having seen it employed in Compiégne i in the fall of 1915; at the War Demonstra- tion Hospital, New York, in the summer and fall of 1917; again in Compiégne late in 1917; and forward of Soissons, in the ‘galvnced U. S. S. GEORGE WASHINGTON BACTERIOLOGICAL CHART see Ward: surg. Nature of the wound. Infected Brush Buins, Left Leg. anterior ‘iddle 5D ESeyr Fret 25GE = Lo Manvanenx, imp. 10-1 F.—.C. Picture taken December 5, 1917. F.—.C. Picture taken December 20, 1917. 10-2 Il. CARREL METHOD. 17 Carrel Hospital, in December, 1917. In November, 1917, on my recommendation, this method of treatment was put into operation on the U. S. S. George Washington, including the Carrel-Dakin treatment proper and various modifications of it. Major Carrel and others of the staff of the Rockefeller War Demonstration Hospital and Rockefeller Institute personally aided in the establishment of this floating war demonstration hospital, fully equipped with ade- quate laboratory facilities, special splints, X-ray apparatus, and photographic plant. Preparation was made for the treatment of 200 cases by the Carrel-Dakin method for one month without the necessity of renewing supplies. We have had most gratifying re- sults where it has been employed. Charts, etc., of two tpyical cases are included herein. U.S. 8. George Washington. Carrel case No. 1 —-Sarpeon, Bainbridge, Wm. S.; date, December 6, 1917; name C., F. E.; rate, Sea., 2c.; age, 26. Date and. nature of wound: November 15, 1917. Loop of rope caught left leg and cut into flesh. It was dressed with a saturated sol. mag. sulph. Worked but became worse. Seemingly well for three days; became worse, glands in groin became swollen and painful, back to sick bay. | , / Date and nature of operation: December 3, 1917. Picture ofleg taken. Condition, cellulitis of leg. Wounds discharging pus, leg swollen. Wet dressing of mag. sulph. December 5, 1917, incision of leg over shin. — e Treatment. Date. Condition of wound. Temp. B. count. 1917 Dec. 6 | Three wounds; 2 burns, 1 incision as | Normal....| Inf. all types. above; 1 tube: No. 3 covered; ‘Dakin’s sol. 30 c. c. q2h. : 7 | Patient states that he has no more |..... do....| Middle 26, anterior 22. pain or throbbing; leg less swollen, : almost no discharge; 3 tubes ap- plied; Dakin’s sol. 30c: c. q2h. 8 | Looking better, less pus; 3 tubes; |.....do.... Middle 9; anterior dry, Dakin’s sol. 30 c. ¢. q2h. - no smear. 9 | Anterior wound cde: middle look- |...-. do....| Middle 6. ing better; 1 tube; Dakin’ s sol. 30 | c. ¢. q2h. 10 | Looking better, no pus; 1, tube; |.....do....| Middle 4. Dakin’s sol. 30 c. c. q2h. : 7 11 | Condition about the same; 1 tube; |..... do....| Middle.5. Dakin’s sol. 30 c. c. q2h. be ae 12 | Wound looking better; a clean bright |...:.do....| Middle 1-5. red color; no pus; it tube; Dakin’s : sol, 30 c. c. q2h. 13 | Condition of wound much better; |..... do.... do. Dakin’s sol. discontinued: chlora- zene cream applied. 14 anch pe chlorazene cream ap- |....-. do.... do. plied. : 15 | Condition of wound much better; |..... do.... chlorazene cream discontinued; ‘thymol iodid applied. 12 II, CARREL METHOD. Treatment—Continued. Date Condition of wound. _ Temp. B. count. 1917 Dec. 16 | Wound much better; thymol iodid | Normal .. applied. ; . 17 | Wound sterile and healing rapidly; |.-.-. do.... dusted with thymol iodid: _ : 18 | Looking well; thymol iodid applied...|..... do.... 19 | Wound practically healed: dusted |..... do.... with thyme iodid; discharged to duty. ¢ silts 20 | Picture taken....:.4.-.-.---- dpaceiceid ah Efe Sects Carrel case No. 10.—Surgeon, Bainbridge, Wm. S.; date, January 5, 1918; name, M., P. F.; rate, SF-2; age, 25. ; Date and nature of wound: November 15, 1917, while standing watch in a lookout aboard the U. 8S. 8..De. Kalb, he got a sudden, pain in his right side so bad that he had to be relieved from duty. Next morning he was admitted to the sick bay. 5 Date and nature of operation: November 17, 1917. An aspirating set was used to draw oft about a liter of milky pus; this relieved the pain for a time. November 18, 1918, transferred to base hospital No. 5 at Brest. December 1, 1917, a second puncture was made, this time drawing off about the same amount of milky pus. Two weeks later an incision was made postero-laterally in the region of the seventh rib of the right side. About three-fourths of an inch of the seventh rib was extracted. Two liters of a milky pus evacuated at this time. Treatment: Dichloramine-I. Slight improvement. Patient had practically no temperature at any time. Patient had been up and about for two weeks prior to his transfer to the U. S. S. George Washington on January. 5, 1918. Treatment changed to the Carrel-Dakin sol. every two hours. Patient improv- . ing rapidly under new treatment. i Treatment. Date. Condition of wound. Temp. B, Count. 1918 Jan. 5 A. M. Dressed at Brest, where D. T. 5 | Great loss of flesh; right chest con- ; Normal... Cavity, pus, granula- tracted; right lung collapsed; regu- tion, inf. all types: lar diet; a tube 8 inches long and 14 cm. in diameter was removed from cavity, followed by about 250 ec. c. of a dark, slimy pus; irrigated with Dakin’s sol. 6; No. 1 tubes in- serted; Dakin’s sol. 120 c. c. q2h. 6 |. Condition a little better, 1 pint of pus |...do...... Cavity 40, pus 16, evacuated; irrigated well with gran. 18. Dakin’s sol.; return well bleached. ; #16 sees Paki sol. 120 c. c. q2h. ondition much better, irrigated out |...do...... Cavity 6, pus 10, gran with Dakin’s sol.; tine normal 9. one ae ea 5 tubes; Dakin’s sol. 120 c. c. q2h. . 8 | Looking much better, much less pus, |...do......| Cavity 4, pus 5, gran. much less contraction of the chest; 6. irrigated with Dakin’s sol.; 6 tubes; aly Deere Bal 120 c. c. q2h. ooking much better, practically no |...do.....- | Cavity 2 3 ; pa 4 tubes; Dakin’s sol. 90 4 c. ths Le a q2h. U.S. S. GEORGE BACTERIOLOGICAL CHART Name: She chest telon Ward: , No. 1-« Nature of the wound... U.S. S. Gecrge Washington, 12-1 1 Preparing to give Carrel-Dakin treatment on U.S. S. George Washington, Sick bay on U.S, S. George Washington 12-2 Date. II. CARREL METHOD. 13 ' 4!" Preatment—Continued. Condition of wound. Temp. B. count. 1918 Jan. 10 il 12 13° 14 15 16 17 Looking much better, less pus, prac- tically no pain; 3 tubes; Dakin’s sol. 90 c. c. q2h. Much better, no pain, no pus; 2 |... tubes; Dakin’s sol. 50 c. c. q2h. Looking much better, small amount of pus, less contraction; patient up and about; great change in strength; putting on weight; blow bottle b. i. d. Looking much better, less pus; blow |... bottle b. i. d.; 2 tubes; Dakin’s sol. 50 c. c. q2h. Patient feeling much better, less |. . pus, no pain; blow bottle bid; 2 tubes; Dakin’s sol. 50 c. c. q2h. Een. aes " weight rapidly, practically no pus; plow bottle b. i. a 2 tubes; Dakin’s sol. 50 c. c. q2h. Continued gain both general and |... local. About ready to permit of closure. ~ Arrived at Norfolk, Va., to be trans- ferred to hospital for treatment... .|: well, is putting on |... Normal. ..| Cavity 1, pus 2, gran. 2. Pay 1-5, pus 0, gran. Cavity 1, pus 1-5, gran. Cavity 1-5, pus 1-2, gran. 1-2. -d0.....4 Cavity 1-5, pus 1, gran: .| Cavity 1-5, pus 1, gran. 1. Cavity, pus, granula- tion. ' Carrel-Dakin titrations during voyage from December 4, 1 917, to December 21, 1917 Stock solution showing effects of time. Dee. 4, WOU ccs cue Se ve bs eeeee sda eeeeenee 3h ease aseeny sys ci aseecalses 12.1 Dees 6; WOM ccc 33 Fee Seetae Sowa eeeee 5 Boa eee eee 6 cceiladwanie ds 11. 9 Decu8, WM sss acacenidie sak sees Rete ied: saa aenae ae nae parbictaie oacevaceee iL.3 Dee: 10;1 917.5. ses oie crac ween saitonesec cn emeuaaueeeeen oe 11.0 Decil2 A Fe cecsece suse paiccecutah oneteaaet ceases eeceeets 10.7 DCC! AD, AOL Fecsescrsce spajssere aie via atone es ees Raided a hiyeic ow Seipeins SeARa LAS cana eils 10.1 Dees lS: LOU Gen ae iste eataasaianis sisiayekGuit: exis POugneeUais: eoss asta 9.2 Dee. 20, VW Fessccsostes sss emcees s oases cbse ss ceteseeees tee st esaeeeacee 8.6 Solution used. Solution used. Dec. 4, 1917......--..--- 12.1 0.45 | Dec. 18, 1917...- 12.1 0. 45 Dec..5, 1917.....-------- 1211] .45 | Dec. 14, 1917....02h..... 121] .45 Dec. 6, 1917.......-.-..- 12.1] .45 | Dec. 15, 1917..........-. 12.1 . 45 Dec, 7, 1917...... Pe ceess 19.1 | AB | 86.16, 1917 ccnaenn cece 121} .45 Dec. 8, 1917 -.-....---.-- 12.1 .45 | Dec. 17, 1917... - 12.1. . 46 Dees 9; 1917 30.2 se sseucws 12.1 .45 | Dee. 18, 1917... 12.1 - 45, Dec. 10, 1917......-.---- 12,1 .45 | Dec..19, 1917......--.--- 12.1 . 45 Dees 11, WOU oc02s2 seins 12.1 .45 | Dec. 20, 1917.....-.-..-- 12.1 ~45- Dec. 12, 1917...--..----- 12.1]. .45 | Dec. 21,1917.......-..-. 12.1 . 45 Lai ae oa The novelty of this method of wound treatment consists in its providing a close and protracted contact between the solution used and the infected wound surface. In order to maintain an unchanged concentration of the antiseptic, a special technique is required for 14 Il CARREL METHOD. the constant renewal of Dakin’s fluid, which is very unstable and easily decomposed. The treatment requires as a preliminary the earliest possible thorough cleansing of the infected wound, within the first six hours, with free incisions, removal of foreign bodies, and excision of all dead or dying tissue. This surgical purification is then supplemented by the Carrel instillation method of wound sterilization by chemical means, more particularly in the form of Dakin’s fluid, which is claimed to be approximately isotonic with blood serum. The point emphasized by Carrel in his treatment is.the principle of its application; which is a direct reversal of the accepted princi- ple of gravity drainage and a revival of the doctrine of antisepsis, not as opposed but as subservient to asepsis. The old Listerian teaching has thus been vindicated, and antisepsis has been developed into a practicable therapeutic procedure. In view of the fact that sepsis is responsible for the loss of countless lives and limbs after recovery from the immediate effects of the traumatism, efficient anti- sepsis seems to offer a more hopeful outlook for the wounded, A most important feature of this treatment is that it permits of early closure of the disinfected wounds by suture, thereby preventing tedious convalescence, threatened septicemia, and more or less loss of function. Under this method, all war wounds are treated as suspects, which means that under no circumstances may such a wound be closed without sterilization under bacteriological control. Clinical appear- ances, no matter how favorable, must be corroborated by micro- scopical examination. On coming under treatment within 24 hours after the infliction of the wound, the patient is placed on the operat: ing table and the affected region is freely exposed by incisions, bring: ing all wound corners and recesses into view. In conformity with modern conservative principles, all vascular, nervous, or tendinous structures are respected as far as practicable. At the same time, an effort is made to convert an irregular angular wound into one large open chamber or cavity. Aside from the radical removal of all foreign bodies and other contaminations, the fleshy tracts of pro- jectiles and the like must be excised as completely as possible, this being the only way to accomplish absolute wound purification. Sac- rifice of muscular tissue under such circumstances is more apparent than real, as extensive sloughing of the walls of seton wounds is sure to-occur. Hemorrhage is to be controlled by means of plain catgut or linen ligatures, which alone are capable of resisting the action of the antiseptic fluid. It is essential.that all oozing be checked with hot saline solution, for the presence of blood not only interferes with proper sterilization, but prevents the taking of satisfactory smears for determining the microbic content. Hidden foreign bodies Il. CARREL METHOD. 15 in the depth of the wound are best located by the X-rays, which ave also useful for ascertaining the presence or absence of bone fractures. Neutral oleate of soda is employed for the preliminary cleansing and again for washing the skin around the sterilized wound, to pre- vent reinfection. The next stage of the treatment consists in the introduction of hypochlorite solution into the prepared wound by means of one or several red rubber instillation tubes, with a lumen of 4 mm.; thickness of wall, 1 mm. When destined to flush a single large cavity, the tubes are open at both ends, whereas tubes’ which supply several smaller cavities are closed at one end and perforated at the. sides. Not the tubes, but the solution must be renewed every two hours, be- cause by that time its efficiency has been greatly lessened by the loss of concentration due to the union of the chlorine with the protein elements of the bacteria and tissues. The renewal of solution is ef- fected without removing the dressings, by the simple expedient of allowing more of the fluid to flow in through the instillatien tubes. The dressing is carried out as follows: Compresses soaked in Dakin’s solution are applied to the wound in such manner as to hold the tubes in position and prevent kinking or other obstruction to the flow. Small squares of gauze, smiearéd with sterilized vaseline, are placed over the skin around the wound to prevent cutaneous irrita- tion which otherwise might follow on prolonged exposure of the skin to the solution. In addition the dressing comprises another layer of gauze, a sheet of absorbent cotton wool, a second sheet of nonabsorbent cotton wool, and. still another layer of gauze. These four layers come ready made in pads, so that they can be quickly applied and easily retained with saféty pins or wooden clothespins. The dressing is applied with the absorbent cotton wool nearest the wound in order to absorb secretions, while the nonabsorbent layer prevents these from escaping and soaking the bed. .The perforate«l portion of the tubes is all beneath the dressing; either upon the wound, if superficial, or inside of its cavity. '-'The nonperforated part is connected with the distributing tubes, which are divided so as to provide as many outlets as may be needed. These distributing tubes are of glass and come either in the form of a Y or a three to four-toothed comb; their lumen is about 7 mm. ‘They are connected with the instillation tube (same lumen) from the reservoir, which is a flask holding 1 liter, with a diameter of 7 mm. at the outlet. This instillation tube is fitted with a pinch cock to control the flow when intermittent instillation is used, and with a drop counter and screw pinch cock to serve in continuous instillation. The latter method is employed only in cases where one tube open at the end is placed in or on a wound. 16 Il. CARREL METHOD. Where two or more tubes with lateral perforations are used, the ' intermittent method alone is practicable. Every two hours the nurse presses on the pinch cock for a few seconds and permits the inflow of enough fluid approximately to fill the cavity. The overflow is caught by the absorbent gauze of the dressing and when properly managed will not wet the patient. Protective pads may be placed underneath, but waterproof wound dressings are prohibited. Chutro uses a shal- low metal pan under the dressing with a tube connecting it with a receptable beneath the bed for possible overflow. The hypochlorite solution in the reservoir is colored pink with potassium permanganate in order to distinguish it from other irri- gating fluids and also to shelter it from the decomposing effects of light. It is a rather unstable solution. , The aim and object of the Carrel method of wound treatment is the continuous contact of injured parts with an efficient nonirritating antiseptic, which is; moreover, a solvent of necrotic tissue. “Other- wise, this dead or dying tissue would maintain infection in spite of the bactericidal power of the instillation. A further most essential feature of the method is the scientific control by way of bacteriologi- cal examination, usually on alternate days, of smears from various parts of the wound to determine its progress toward asepsis. The time for closure of the wound by suture is governed by the labora- tory reports, and has not arrived until: the proportion of bacteria under the microscope is as low as one to five or six fields. 'The smears are taken by the surgeon himself after the instillation has been dis- continued for two hours. When closure under these conditions is followed by a rise of temperature and evidences of local disturbance. the wound must be reopened without delay and search made for an undetected foreign body. If such be discovered and successfully removed, the wound may be closed again after a second period of observation. Sometimes in long-standing cases bacteria are im- prisoned in cicatrices and set free when an attempt is made to close the parts. More or less incomplete sterilization is indicated by pain and rise of temperature and calls for an immediate repetition of the course of instillation. Regarding the composition of the antiseptic agent used in this method, the neutral hypochlorite of soda was selected by Dakin, after considerable experimentation, as the most advantageous and nonirritant to the interior of the wound, although slightly attack- ing the skin. The latter can be simply and effectively protected by means of vaseline. Soda hypochlorite in a concentration between. 0.45 and 0.5 per cent destroys all bacteria without distinction. Be- low 0.45 it loses its bactericidal powers; while above 0.5 the tissues will not tolerate it. Between these two extremes it will disintegrate pus-cells and dissolve necrotic tissue, being superior in this respect Il. -CARREL METHOD. 17 to chloramine, a better antiseptic, but without the power of dissolv- ing necrotic tissue. Moreover, chloramine decomposes more rapidly on contact with the tissues and must therefore be used in larger amounts than soda hypochlorite, which after exhaustive experimen- tation under identical conditions is advocated by Carrel as the best available. It is cheap and readily made up, provided care be taken to secure the correct ingredients and to make the proper combina- tions. Dakin’s fluid is prepared according to two fowraulad. one with and the other without the addition of boric acid, the latter having proven most acceptable in practical experience. ‘The process of making the solution is described as follows: Neutral hypochlorite prepared without boric acid is best made according ta the formula given by Daufresne, and at the present time is perhaps more generally used than any of the other modifications. Two hundred grams of good bleaching powder are put in a 12-liter bottle with 5 liters of tap water. The solution is shaken vigorously and allowed to stand for at least six hours. unless a mechanical shaker is used, when half an hour’s shaking will be found sufficient. In-another vessel, 100 grams of dry sodium carbonate and 80 grams of sodium bicarbonate are dissolved in 5 liters of cold water and then added to the bleaching powder mixture. The whole is shaken vigorously for a few minutes, and the precipitate allowed to settle. At the end of half an hour the clear solution is siphoned out and then filtered through paper. The proportions given above for the carbonate and bicarbonate of soda are those given by Daufresne. It is our experience, however, that with most brands of American bleaching powder it is better to use 90 grams of each salt. This solution must invariably be tested for neutrality by adding a pinch of solid phenolphthalein to a little of the solution. If, the solution should give an alkaline reaction, one of three methods must be employed to correct it, otherwise skin irritation will ' surely result. (a) Pass carbon dioxide gas into the solution until a sample shows no alkalinity when tested as described. This is perhaps the best method. (0) A neutral hypochlorite may be secured by reducing the proportion of carbonate of soda and increasing the bicarbonate. (c) Boric acid may be added until neutrality is secured. An advantage ‘of the carbonate preparation is that it possesses greater stability and can be kept for several weeks without much deterioration. On the other hand, with varying qualities of bleaching powder, containing different amounts of free lime, it is more difficult to adjust the proportion so as to obtain a neutral solu- tion directly. Probably those having adequate laboratory facilities will prefer the carbonate-bicarbonate solution, while the mixture containing boric acid is readily made under less favorable circumstances. Titration of the solution.—Measure 10 c. c. of the solution, add 20 ¢. ¢. of 1:10 iodin solution and 20:c. c. of acetic acid. Pour into this mixture a decinormal solution (2.48 per cent) of sodium thiosulphate (hyposulphite) until decolora-, tion. Let N equal the number of cubic centimeters of thiosulphate employed. Then the quantity of sodium hypochlorite for 100 c. c of the solution would be” giyen by the equation: T=NX0.08725. Precautions.—Never heat the solution. If, in case of ah emergency, it is necessary to titrate the chlorinated ims; use only water, never with the solu- tion of soda salts. 2 18 ll. CARREL METHOD. Other means of preparing the hypochlorite solution. by passing chlorine gas into soda solutions are coming into favor, because of the readiness of obtaining ‘an exact chlorine concentration without the trouble and delay of titrating the lime. Transportation of the chlorine tanks is as easy as that of the lime outfit. We have found the chlorine gas method very satisfactory on one of our largest trans- ports. Thousands of these gas tanks have been ordered for the United States Army. , The apparatus for making Dakin’s solution directly from liquid chlorine (designed and manufactured by Wallace & Tiernan Co., New York, tested and indorsed by the Rockefeller Institute, and shown in the illustration) consists of a seamless steel cylinder of chlorine with a special regulating valve, connections from the cylinder to a meter, connections from the meter to a diffusor stem and diffusor for dis- tributing chlorine in the sodium carbonate solution. Pure anhydrous chlorine can be obtained in compressed cylinders of various sizes. The second illustration shows the arrangement suggested for connecting the apparatus to a large cylinder. The valve in the head of the large cylinder is not sufficiently sensitive to control the minute quantities of chlorine passing through the Dakin’s solution apparatus. It is therefore necessary to attach to the main tank valve as shown, an auxiliary tank valve capable of fine adjust- ment as indicated in the cut. The connection from the auxiliary tank valve to the meter block is made as shown. The progressive sterilization of infected war wounds is ascertained through the bacteriological control of the wound, an essential feature of the Carrel treatment. Smear specimens are prepared from time to time, according to the judgment of the surgeon in charge, and the number of germs in several microscopic fields is estimated, espe- cially toward the end of the treatment, when the question of closure by sutures enters into consideration. Practically complete absence of germs is noted in the average case at the end of from 4 or 5 to 12 days’ treatment of soft-part wounds free from gangrenous tissue, or from 13 to 25 days in extensive wounds complicated by fractures, When treatment can be begun within 24 hours after the infliction | of the wound, sterilization is as a rule rapidly accomplished. Two weeks or more may be required to sterilize a compound fracture, uncomplicated by gangrene, when the instillation is begun within 24 hours. In such cases, after the sterilization has been effected, large bone splinters may be fixed in position with Beck’s paste, or large gaps bridged with adipose grafts, after which the wound may be closed and managed as a simple fracture. Neglected or improperly treated inflamed wounds of more than 24 hours standing may be bathed with the Dakin solution, and fomen- tations of hot water and alcoho! applied, but local interference is ‘dapul[AD aulsojyd adie] UyIM Snyesedde uoljynjos s,uly4eq 3 “snyeiedde uoljnjos s,ulyeg vounos \\ ORV? WADE wns yosnsaa——~ | “aen weet} } ANA on, INNO LP 18-1 War Demonstration Hospital, New York, The War Demonstration Hospital. Carrel-Dakin method of treatment being demonstrated at a special course given for Army and Navy surgeons by Dr. Carrel. Prof.W.W. Keen speaking to class, contrasting treatment of wounds in the Civil War and the present war. 18-z Il, CARREL METHOD. contraindicated during the inflammatory period, which lasts several days or even weeks. Suppuration once established, existing abscesses may be evacuated and instillation tubes introduced, postponing the search for foreign bodies or the exposure of sinuous tracks until more favorable conditions have been provided by the antiseptic solu- tion. The Italian proverb, “Chi va piano va sano,” is a good one to follow in these cases. Should convalescence be unduly protracted, with persistence of microbes notwithstanding careful observance of all rules of treat- ment, the wound must be explored in order to discover the cause of the trouble; which may be in the form of ‘minute foreign bodies, particles of necrotic bone or infected marrow, fistulous tracts, or the like. Neglected wound recesses, not reached by any tube, are frequently responsible for delayed healing. One of the conducting tubes may slip or drop; or one or more tubes may become bent or kinked. Again, the instillation apparatus may have been incorrectly installed, or the relative calibers of the several tubes may not cor- respond to the rules for the treatment. _At the War Demonstration Hospital of the Rockefeller Institute in New York, where everything needed for the complete exposition of the subject lies been provided, large numbers. of surgeons have been enabled to: study this valuable method of wound sterilization prac- tically as well as in the war hospitals abroad. A hospital with 100 beds, with a first-class equipment for this particular purpose, has been erected, and! nothing is. omitted in the demonstration of every feature of ‘he treatment and in the exhibition of the theory and prac- tice of this novel adaptation of Lister’s teachings to, the wounds of modern warfare. The teaching includes the preparation of the solu- tion and of the patient; the adjustment and operation of the instil- lating apparatus; the application of the dressings; the taking and testing of smears; briefly, the entire. technique of the method. The clinics of Major Carrel and lectures of Dr. Loewy have contributed largely to the popularizing of the system among the students, who thus have become acquainted with it theoretically at the fountain- head of information, and practically through some of the trained members of Carrel’s Compiégne staff. The regular course given by Major Carrel, with Dr. Dehelly and Dr. Loewy, has attracted, many United States Army medical officers and.a few Navy men. Dozens of hospital corpsmen have been enabled to take interim courses in the hospital between trips. Small groups are instructed at a time for a period of 10 days to two weeks. This hospital'thus provides an excellent and accurate demonstration of the treatment as it should be carried out according to the ideas of its originator. However, one can not here form an accurate esti- mate of the results in the treatment of war wounds, for the horrors 20 Il. CARREL METHOD. of infected wounds at home are as nothing compared with those abroad. The underlying principles of wound sterilization are applied uni- formly in recent as well as in long standing wounds, the technique varying only according to the mechanical difficulties attributable to the location of the injury. The solution must be kept in contact with all parts of the damaged area, and this is difficult to accomplish in wounds so situated as to be quickly drained. In such cases the effects of gravity must be counteracted by plugging the dependent aper- ture with gauze, so as to make a basin of the cavity. Under no circumstances must gauze be allowed to come between the tube and the discharges, as this would prevent the penetration of the steriliz- ing fluid. . Wounds of the brain require thorough sterilization after the care- ful removal of the projectile or any other foreign bodies that may be present. It is essential that the solution be brought into contact with all parts, but extreme caution is needed to guard against dam- age being done to the delicate cerebral tissue. A special apparatus has been constructed for the purpose, which to quote Carrel, consists of “an external tube permeable to liquids, and an internal tube of small caliber by which the antiseptic substance is injected. The external tube consists of a very light framework, on which is stretched a thin fabric which has been rendered hydrophilous. This frame- work Du Nouy constructs of bamboo hollowed and perforated by a thermo-cautery, while Daufresne makes it of thin wire. The diameter of these tubes varies from 1 to 1} centimeters, and the length from 4 to 6. In the interior of the tube is fixed a small rubber tube about 2 millimeters in diameter, which is attached to the framework. « This little appliance is fixed in the cerebral wound so that the movements of the head can not displace it. The meninges are protected by a. piece of gauze impregnated with vaseline. The appliance is con- nected with a special apparatus which instills we liquid drop by drop.” Many claim that Dakin solution is too irritating for brain cases; others employ it and agree with the staff at Compiégne that it can be used advantageously in cerebral surgery. Secondary hemorrhage, which is occasionally encountered, may be due to the destruction of the silk or chromic catgut ligatures by the hypochlorite solution. Plain catgut or linen is safer. It may some- times be attributable to a faulty Dakin solution, which with free alkali will be capable of ulcerating blood vessels as quickly as Labar- raque’s solution. Again, it may result from the breaking down of a hemostatic clot under the influence of infection. It can be prevented by care in the initial control of hemorrhage. Its occurrence must be met by prompt ligation above and below the danger point. Il. CARREL. METHOD. 21 Several methods of closure are available when the microscope de- cides that the proper time has arrived. Strapping with adhesive plaster across-the wound is perfectly satisfactory when the skin is movable and cicatrization has not begun. There is no pain and no need for anesthesia. A strip of sterilized paper or celluloid should be laid along the wound to prevent reinfection by the plaster, which is not sterile. When the wound is gaping and can not be closed com- pletely, elastic tension may be applied to it and gradual coaptation of the edges be brought about. Strips of plaster three inches wide and long enough to extend 2 inches beyond the wound at both ex- tremities are laid parallel with it and are fitted with shoe-lace hooks which are connected across the wound by means of elastic lacing. The traction exerted by the elastic laces gradually draws the edges near together, and even if complete closure can not be effected: be- cause of the loss of tissue there is a great reduction in the interspace left: to cicatrize. : If suture should be selected as the means of closure, general anes- thesia may best be employed. The skin should be released from the deeper parts if adherent, and its edges freshened by being cut away for the width of about 2 millimeters. Deep suturing may be needed for divided aponeuroses, for example. The bacteriological examina- tion having shown the requisite freedom from bacteria there is no need of drainage. As soon as the wound is in this condition, divided muscles, tendons and nerves should be brought together. Wounds associated with fracture may be closed, as a rule, the same as wounds of the soft parts. Even in badly crushed limbs, if asepsis can be secured in a few days closure may be effected without any anxiety regarding the bony element of the problem. It will take care of itself. In certain old fractures it-may be necessary to fill an osse- ous ‘gap with Beck’s paste or an adipose graft. Amputation is nearly always the consequence of infection. An infected wound can not be closed primarily, and hence there is a marked tendency of the soft parts to contract. This may be over- come in great measure through traction, by means of adhesive plaster and a weight. The necessary apparatus does not interfere in the sterilization of the wound. On amputation stumps, a loop of tub- ing perforated in its middle portion and connected with a Y dis- tributor may be laid next the tissues, and the fluid carried all over: the area at the stated intervals. After a few days, according to the bacteriological improvement, the stump may be sutured and treated like any other fresh aseptic operative field. Joint injuries are treated on the same principle. Simple. lacera- tien of synovial membranes quickly resolves under the instillation methed. Even where bone injury has occurred, better results and fewer resections follow the gradual sterilization. ‘In‘streptococcic in- 22 I. CARREL METHOD. fection of the joints, amputation has to be gravely considered. If the surface of the bone should have been abraded by the missile ‘it must be scraped to get rid of any infectious material. The results claimed by Carrel for this departure in the manage- ment of war wounds are in broad general terms the salvation of life and limb under circumstances heretofore considered prohibitive. Specifically he cites the “diminution in the frequency and intensity of general complications; diminution in the number of amputations; diminution in the length and cost of treatment.” Under the first heading is cited the fact that of 303 cases received from advanced dressing posts in the hospital at Compiégne from December, 1915, to October, 1916, 13 died “after a stay in the hospital of more than 24 hours.” Of these, eight had extensive visceral damage, and three had “multiple wounds of thorax, lower and upper limbs.” Two cases only died of septicemia. One was due to gas gangrene, the other to staphylococcus infection following extensive damage to the femur. Under the second head, the suppression of infection prevented the complication of lymphangitis, abscess and purulent tracts, thus dimin- ishing the number of amputations. In one year, only three abscesses were observed. Where the extent and character of the lesions did not allow of speedy sterilization they did allow of a great deal of local improvement. This favored the conservative management of many wounds ordinarily calling for amputation. From December, 1915, to October, 1916, only 23 amputations were performed, and where resection of joints was the usual course, the simpler expedient of arthrotomy and sterilization sufficed to save the limb. The am- putations were due mostly to such extensive destruction of tissue that nothing else was possible. In only three cases was the cause sepsis. Two have been referred to. The third was a “fracture of the upper part of the forearm with extensive vascular destruction and considerable diminution of the circulation of the limb.” This patient recovered. At the hospital at Villars, M. Perret amputated only once in 100 cases. In another series of 100 infected cases MM. Guillot and Woimant did not amputate at all. Under the third heading “diminution in the length and cost of treatment,” Carrel claims that wounds of the soft parts, no matter at which stage treatment is begun, are closed in 90 per cent of the cases between the 5th and 20th day. The other 10 per cent heal more slowly but much faster than under other forms of treatment. Six months would otherwise be needed to close many of these which are closed in less than one month. The duration of wound treatment is reduced two-thirds. In compound fractures “of short bones, flat bones, and such long bones as the fibula, radius, and ulna, the same progress was made as with wounds of the soft parts.” Under “ ordi- nary methods such fractures sometimes suppurate for months.” With Case No, 1.—Wound closed, 22-1 ° Pd © b ao pa) rma = Ps o a eae a oO o ba] in 9 £ # bo 22-2 Case No. 2.—One of Dr. Carrel's cases. Large shell wound trav- ersing the anterior aspect of the thigh and almost completely divid- ing the quadriceps femoris. Three anda half hours after the re- ceipt of the injury the wound was laid open and foreign bodies and torn muscular tissue removed. An extensive wound resulted more than 10 centimeters long and extending from one side of the thigh to the other. Case No, 2.—At end of seven days the patient walked normally. Tl. CARREL METHOD. 23 regard to compound fractures of the “tibia, humerus, and femur. considerable diminution in the duration of treatment is also pro- duced.” The cost of treatment is lessened by the shorter period of care. The materials used are cheap. The net cost of a quart of Dakin’s solution is less than 1 cent. Dressings are but slightly soiled and may be resterilized for further use. The method favors the speedy suturing of nerves and tendons which in a condition of prolonged suppuration would be impossible. Hence the saving of function is very great. On an average, 97 per cent of old bone sinuses coming to him for treatment are now closed by Chutro, who has used the Carrel-Dakin treatment in all infected cases since 1916 with excellent results. The time required before closure usually amounts to 30 or 40 days. Pozzi, surgeon in the Hépital Militaire du Pantheon, was an early advocate strongly in favor of this mode of treatment. Edred M. Corner, M. C., F. R. C. 8., chief surgeon in the Fifth London General Hospital. St. Thomas's Hospital and the King’s Hospital, writing in the Clinical Journal of London, April, 1918. advocates this method and quotes Sir George Makins’s paper in the British Journal of June 16, 1917, to the effect that “ At the present time the most successful eesti which are being attained in all forms of wound treatment are undoubtedly those in which the Carrel- Dakin: method i ‘is employed. ue In the British Medical Journal of June 2, 1917, Sir Anthony Bowlby and Mr. Cuthbert Wallace say that “the method of Dr. Carrel has been increasingly used and wounds treated in this way have done exceptionally well.” Sir Almroth Wright, who objects to Dakin’s fluid on several grounds, considers the Carrel method as the most, important contri- bution made to surgical antiseptic technique since the beginning of ithe war, which moreover provides a new and improved technique for physielogical treatment of infected wounds (Lancet, June 23, 1917). Sir Thomas Crisp English, on his return from Salonica and Italy, in an interview with me in London and in a subsequent written com- munication, summed up his experience as follows: “I feel that the Carrel-Dakin treatment is great. I used it extensively in Salonica with excellent results. All of these things call for an open mind and no dogmatic utterance.” In their notes on recent surgery in Salonica (Brit. Med. Jour.. March 16, 1918), Colonels English and Kelly, on the basis of their ex- perience as consulting surgeons of the British Salonica force, state that the general treatment of wounds has followed the same evolu- tion as in other theaters of war. At first the ordinary eusol dressing 24 Il. CARREL METHOD. was most in use. A reaction in favor of the hypertonic saline solu- tion and salt packs then set in. Finally, Carrel’s method of treat- ment has become the one preferred. They emphasize the advantages of continuous wound treatment by one method, and the desirability 4 of adopting a standard plan of treatment, provided an ideal method | can be found. “Carrel’s method of treatment; ” they go on to. say, “appeared to us to approach most closely to the ideal, and during the past eight months it has been used as’ the standard method. in many of the hospitals. Other forms of wound treatment have been in use, but we have not yet seen with them the same consistency of results, the quick sterilization of the wound and its secondary suture, which certainly occurs with Carrel’s method.” The rapid and radical removal of all necrotic tissue is now gener- ally conceded to be imperative in checking infection. In the appli- cation of the Carrel-Dakin treatment the proper preparation of the wound in this particular is assisted and supplemented by the. con- stant contact of the damaged tissues with a neutral hyperchlorite solution having a powerful proteolytic action. While further, re- search must show the exact nature of the resulting chemical changes; the activation of proteolytic processes may even now be considered the best-fitting key to the success achieved by the Carrel-Dakin method of treating infected war wounds. Regarding the mode of employment of hypochlorite solutions, sev- eral types of simplified instillation apparatus have been devised which obviate the necessity for a trained hospital staff, carrying into. the wound at stated intervals an amount of antiseptic fluid which. can be arbitrarily regulated. The use of soda hypochlorite solutions has been objected to on the following grounds: (a) their irritating effect upon the skin;. (0) their brief efficiency; (c) the necessity for uninterrupted contact of the antiseptic fluid with all wound recesses. The dichloramin-T in oil method, described. later herein, was devised by Dakin for the removal of ‘these and other minor objections. The double chloramin . used is known commercially as chlorazene; it is dissolved in chlorin- ated: eucalyptol, or chlorinated liquid paraffin may be added. The oils are chlorinated to limit their decomposing action on the di-. chloramin-T. The bactericidal action persists longer than the -ac- tivity of hypochlorite solutions. The dressing is simplified by. the elmination of the Carrel tube, the dichloramin-T being sprayed over superficial wounds or poured into deep wounds as into a cup. How- ever, the oily fluid does not seem to reach the deep corners of war wounds as the watery solutions do. Besides, necrotic tissue is not dissolved by dichloramin-T, which is all-important in many cases. The consensus of opinion is tending strongly toward the retention of the hypochlorite in the Carrel-Dakin treatment and the employing French.surgeon giving a practical illustration of the Carrel-Dakin treatment. Hospital corpsman learning to adjust splints at the War Demonstration Hospital, New York, 24-1 War Demonstration Hospital, New York. Hospital corpsmen learning the Carrel-Dakin treatment. 24-2 Il, CARREL METHOD. 25 of dichloramin-T as a spray in certain infections of the throat, and, if used at all in wounds, only in those which are superficial. Chloramin paste contains 8 per cent of sodium stearate and 4 to 15 parts per 1,000 of chloramin-T. “It is designed to maintain in an aseptic condition wounds which have already been disinfected, or to sterilize slightly infected wounds. It should only be applied to wounds which yield small quantities of secretion, have little or no necrotic tissue, and little or no infection. Neutral sodium oleate is poured into the wound and the surrounding skin from a flask with asmall opening. The granulations, the epithelial edges, and the skin are gently swabbed with a piece of absorbent cotton attached to a forceps. (Great gentleness is required so that there will be no bleeding from the surface-——W. S. B.) By this means an excellent cleansing process is effected. The patient should feel no pain; any suffering indicates either that the sodium oleate is incorrectly pre- pared or that the cleansing is imperfectly carried out. The sodium oleate is removed with a plug of cotton soaked in water, and the sur- face of the skin is dried by carefully applying a compress of absorb- ent gauze. A sufficient quantity of chloramin paste is withdrawn from the receptacle by means of a sterilized wooden spatule and applied to the surface of the wound to the thickness of at least 1 centimeter. It should cover not only the granulations, but also the epithelial edges and part of the surrounding skin. If the wound should be deep and anfractuous, the tube containing the chloramin paste is introduced into the opening, and sufficient chloramin paste is expressed to fill the cavity. But no pressure should be applied during the process. A compress of dry gauze, much larger than the wound itself, is next placed over the chloramin paste. The compress is applied to the surface of the skin and attached to it by means of two or three strips of adhesive plaster. It is important that the gauze should be placed exactly over the wound, for if the bandage is shifted the gauze will introduce bacteria from the surrounding skin on the surface of the granulations and reinfection will ensue. Above the gauze is placed a piece of absorbent cotton enveloped in gauze. The dressing must not be compressed by bandages and should be renewed every 24 hours. The wound is washed out with sodium oleate every ‘day or two, depending on the condition of the skin. The application of chloramin should be painless; any sensation of pain signifies tech- nical error on the part of the surgeon. The bacteriological condition of the wound is examined every day in film preparations of secretions taken from various parts of the wound.” (Carrel and Hartmann, Jour. Exper. Med., July 1, 1918, p. 95.) While claiming brilliant results and supported by eminent sur- geons, the Carrel-Dakin treatment is opposed by surgeons. just as eminent. Thorough wound cleansing, with immediate suture is held 93696—19-——3 26 It. OTHER METHODS. in high esteem and is undoubtedly the ideal method. for treating many cases received at a very early stage. The use of other anti- septices besides the hypochlorites and the chloramines, either in con- junction with the Carrel method of instillation or without it, is also credited with most successful results. Certain excellent authorities with large experience condemn the use of all antiseptics on the ground that they damage still further the injured tissues and eon- tribute nothing to the healing process or the prevention of infection, The failure of so many able and honest men to agree upon a uniform method of treatment suggests the suspicion that each has hold of a thread of the truth but does not perceive the whole, which is that while much depends upon the sort of wound and the period when it comes under treatment, more depends upon the judgment and skill of the surgeon in first selecting the proper method for each particular case and then applying it. a: Personal observation in the war zone of the various modern methods of treatment, and the excellent results accomplished by many of them, leads me to accept the judgment of a growing number of surgeons that while most of these methods have definite fields of usefulness, none of them is a panacea. The revival of the sixteenth century practice of immediate wound closure, with thorough dé- bridement, is of undoubted value, and there is reason to hope that it will not again be relegated to the limbo of forgotten things, re- quiring rediscovery in wars to come. Meanwhile, the Carrel technique has come to stay, as through its employment certain great truths have been revealed. Asepsis, whenever possible, reinforced by antisepsis as required, is the keynote of success. ‘The type of antiseptic and the extent of its employment, may be definitely de- termined by the future, but at present they are largely matters of individual opinion and preference. III. OTHER METHODS. At the many centers visited, numerous antiseptic agents were be- ing employed and varying opinions were held as to the value of such agents. I have attempted to set forth the more important of these and the claims made for them by their originators or those using them, as follows: a HYPOCHLOROUS ACID PREPARATIONS—EUSOL AND EUPAD. The antiseptic action of hypochlorous acid, and its application to wound treatment, was pointed out in 1915 by Lorrain Smith, Drem- man, Rettie, and Campbell, of the department of pathology in the University of Edinburgh. The hypochlorous solution is known as eusol, which is standardized at 0.5 per cent of hypochlorous acid, St. Bartholomew's clinic. Hospital corpsmen making Dakin's solution, St. Bartholomew's clinic. Hospital corpsmen strapping a sprained ankle and preparing Dakin’s solution, 26 Il, OTHER METHODS. 04 and was originally prepared on a large scale from dry bleaching powder and boric acid. In smaller quantities, eusol is advanta- geously prepared, at a moment’s notice, by diluting and mixing two stable stock solutions, as follows: Preparation of eusol—Take 185 c. c. of liquor calcis chlorinatae (a 10 per cent solution of bleaching powder in water) ; dilute with water to 1 liter; add 10 grams of boric acid, and shake until dis- solved. The solution remains clear, and without further treatment is ready for use. If preferred, a saturated solution of boric acid may be stocked at room temperature; this contains 4 per cent boric acid, therefore 250 c. c. give the amount required for 1 liter of eusol. In making eusol in this way, the 185 c. c. of liquor calcis chlorinatae should be diluted to 750 c. c. and the 250 c. c. of boric acid solution added. This prevents the formation of the precipitate which occurs if boric acid be added to undiluted liquor calcis chlorinatae. Preparation of eusol for intravenous injection in septicemia.—F or this purpose, it is necessary to add sodium chloride in the proportion of 8.5 grams to the liter. In this case, therefore, the 135 c. c. of liquor calcis chlorinatae would be diluted to 500 c. c. with distilled water, the 250 c. c. boric acid solution added, and also a solution containing 8.5 grams of sodium chloride dissolved in 250 c¢. c. of distilled water. These methods of preparing eusol were published in the British Medical Journal, September 22, 1917, by J. Lorrain Smith, Tirchie, and Rettie, who say that since liquor calcis chlorinatae keeps well, the method described above has suggested itself as a simple and con- venient way of preparing eusol in any quantity desired. Each liter of the liquor yields at least 7 liters of eusol. (The quantities given in the prescription are calculated on a chloride of lime assaying 25 per cent available chlorine, which is the average obtained from'commercial samples at the present time.) Eusol may also be prepared as follows: To 1 liter of water add 12.5 grams of bleaching powder, shake vigorously, then add 12.5 grams boric acid powder and shake again, allow to stand for some hours, preferably overnight, then filter off, and the clear solution is ready for use. The solution contains: Per cent. Hypochlorous acid 0. 54 Calcium chlorate 1. 28 Calcium chloride _-_------~---------- 4 .17 Total / 1.99 Another method of preparing eusol.—Shake up 25 grams of eupad (equal parts of commercia. bleaching powder and boric acid, inti- mately mixed and ground in a mortar) with 1 liter of water. Let 28 Ill, OTHER METHODS. stand for a few hours, then filter through cloth or filter paper. Keep the mixture in a closely stoppered bottle, and do not expose to light. Eupad is the name given to hypochlorous acid in powder form, and consists of equal weights of finely ground bleaching powder (chloride of lime) and of boric acid. Hypochlorous solution, electrically produced from hypertonic saline, was recommended as a strongly bactericidal disinfectant for septie wounds, by Beattie, Lewin, and Gee (Brit. Med. Jour., I, 1917, p. 256). Their apparatus can be installed in any hospital or institution, and a supply of the solution produced at a very small cost. The lymph flow in the wound is encouraged by the hypertonic solution which is used for the production of the hypochlorite. Sur- face bacteria on septic foci seem to be destroyed almost immediately, and the stimulating action on the lymph. fiow tends to wash to the surface the more deeply situated organisms. It is claimed that this lymph increase is very evident in the wounds treated with this solution. Mode of preparation of eusol, according to Fraser and Bates (Jour. Roy. Army Med. Corps, London, Vol. X XVII, 1916, p. 791): “In a Winchester quart bottle 27 grams of dry bleaching powder were placed, and to this 1 liter of water was added; the mixture was shaken, and 27 grams of boric acid were added; the bottle was now filled with water, the solution was thoroughly shaken, allowed to stand for a few hours, and then filtered through cotton wool. The ‘clear solution is eusol; it is slightly alkaline to litmus and it contains approximately 0.5 per cent hypochlorous acid. The solution was stocked in air-tight stone jars.” The same writers report most gratifying results from intravenous injections of eusol, varying in amounts from 40 cubic centimeters to 70 cubic centimeters in cases of autotoxemia subsequent to infec- tion of a wound with gas-producing organisms. Packing with salt sacks (Gray’s method), to which eupad powder has been added, is advocated in the treatment of septic gunshot wounds on the basis of good results in a large series of cases by Major Hull, of the Royal Army Medical Corps. A convenient method of combining the eupad with salt is to pack the wound with ordinary salt sacks sterilized in the autoclave and introduce into the middle’ of the sacks without touching the wound an unsterilized sack filled with eupad. (Sacks filled with eupad and salt in the proportion of one to three are destroyed in the autoclave owing to the corrosive action of the hypochlorous acid upon the fabric.) The solid salt sack consists of a two-walled sack of suitable size, made of bandage, between the layers of which four layers of gauze are placed. The interior of the sack is filled with salt and the tail of the bandage forms a drain. The sacks are made in different sizes, sterilized in Il.. OTHER METHODS. 29 _an autoclave and stored ready for use. One or more of these sacks is used to pack wounds, the spaces between the sacks being filled with gauze. A tube of perforated zinc or rubber may be passed into the depth of the wound in case of large septic wounds. Six days may be said to be an average time for the sacks to remain in the wound. The successful results of this treatment largely depend, as all treatment of septic wounds must, upon an early attack on the sepsis and upon the thoroughness with which it is possible to remove septic and necrosed tissue. : SALT PACK METHOD OF WOUND TREATMENT. The salt pack treatment of wounds was introduced by Colonel H. M. W. Gray (Brit. Med. Jour., I, 1916, p. 1), for the purpose of pro- moting a lymphagogue action and obviating the need for elaborate drainage or continuous irrigation. As to results of the treatment with salt pack, Donaldson and Joyce write in The Lancet of Septem- ber 22, 1917: “The adoption of this method has considerably cur- tailed the patient’s period of convalescence, and has, moreover, suc- ceeded where other methods have failed, including the much-advo- cated Carrel-Dakin procedure.” The method is distinguished by its simplicity, the avoidancé of daily dressing of the wound, the prompt development of healthy sur- face granulations, and rapid improvement of the general condition. Application of tablet and gauze packs.—After the wound has been cleaned by operation, all the recesses of the wound (these recesses should be sought out by the finger) are filled, fairly firmly, with gauze wrung out of 5 to 10 per cent salt solution, in the folds of which are placed numerous tablets of salt. Blood clots which may form during the packing should be wiped away. The gauze should be packed concertina-wise, a tablet being placed between every third or fourth fold. A fairly large, fenestrated rubber tube is placed so as to reach to the deepest part of the main cavity, which is then filled with gauze and tablets. The dressing is made flush with the skin and the tube projects slightly from its midst. The surrounding skin is painted with solution of iodine or other antiseptic application. Two or three layers of gauze are then used to cover the wound and surrounding skin. A suitable amount of absorbent cotton wool is applied and a bandage wound on smoothly and firmly. Should pus collect in any isolated part of the wound, it is not necessary always to remove the whole of the pack, and thus to cause the patient unnecessary pain, and to jeopardize the healing of the rest of the wound. Irrigation and drain- age of the affected part may be instituted. The rest of the “ pack” will prob- ably become loose in a few days. If it is suspected that any part of the wound will give trouble in this way, a drain down to that part should always be inserted. In the answers to questions regarding saline treatment sent to 22 hospitals in July, 1915, tablet and gauze packs were judged to be best for deep and fairly recent wounds. 30 Ill, OTHER METHODS. DICHLORAMIN-T. This chlorine compound was introduced by Dakin, and on account of its greater chlorine content is claimed to exert a much stronger germicidal action than the sodium hypochlorite solution used as Dakin’s fluid in the Carrel method of wound treatment. Its basis is a by-product in the manufacture of saccharine, and it is known commercially as chlorazene. The conclusions arrived at’ by Professor Sweet, working with the _ United States Army Base Hospital No. 10, in France, show that Dakin’s dichloramin-T, in solution in eucalytol and paraffin oil, is of great advantage in wound treatment, because— (1) It saves the pain of wound dressing. (2) It effects an appreciable saving of dressing material. (3) The amount of solution needed is small in bulk. (4) The number of wounds which a surgeon can dress in a given time is far greater than by any other method. (5) The elimination of the Carrel tube simplifies the dressing and the problem of transportation of the wounded. (6) The elimination of the Carrel tube saves the time taken by the nurse for the periodic flushing. Lieutenant Commander R. G. Le Conte, Med. Corps, U.S. N.R.F.,, of Navy Base Hospital No. 5, is a strong advocate of this agent in war wound treatment. Some, however, have found its usefulness confined to superficial wounds. Others who were at first enthusiastic have now discarded its use. Some very favorable reports have recently been made on the value- . of dichloramin-T solution, 1 or 2 per cent in chlorocosane, as a spray in infections of the upper air passages. “ Chlorocosane” is an oil obtained by the chlorination of paraffin wax, and has been found by Dr. Dakin and Dr. Edward K. Dunham, of New York, to be the most satisfactory solvent. They describe as follows the way in which the antiseptic action of dichloramin-T is exerted: It is well recognized that antiseptics incorporated with or dissolved in oily substances usually possess little, if any, antiseptic activity, because intimate contact with the infected matter is hindered by the oil. When, however, such oil solutions of dichloramin-T as will be described are brought in contact with aqueous media, the partition coefficient between the oil and the water is such that a certain amount of the dichloramin-T passes into the water and there exerts its germicidal action. The amount of dichloramin-T thus passing from the oil is enhanced by the presence in the aqueous medium of substances capable of taking up chlorine, so that the oil solution serves as a store for the antiseptics, which is drawn upon to maintain the germicidal activity of the aqueous. medium with which it is in contact. Thus the amount of antiseptic leaving the oil solution is, to a certain extent, dependent upon the rate at which it is used up in the aqueous médium. Ill, OTHER METHODS. $1 MAGNESIUM SULPHATE. The practice of Morison and Tulloch (Jour. Roy. Army Med. Corps, London, Vol. X XVII, 1916, p. 375) in treating recent wounds, both of bone and soft parts, has been to swab the wound freely with pure carbolic acid, packing it afterwards for 24 hours with gauze steeped in carkclic lotion (1 in 20). This, together with free and de- pendent drainage, has been frequently successful in obviating or minimizing sepsis. This is followed at the end of 24 hours by the application of the magnesium sulphate dressing, which is painless and easily carried out. Even in the most septic cases the dressings need be changed only twice a day. The effect on the wound is very striking. In two or three days pus has almost disappeared, sloughs begin to separate, and the whole sur- face presents a bright color. The granulations never become flabby or edematous, but instead a firm vascular healing wound is seen. Scratching the surface of the wound with a probe hardly disturbs the vascular granulations. The growth of epithelium from the edges . of the wound proceeds vigorously, and the treatment may be con- tinued with advantage until the entire wound is healed. The result- ing scar is firm and elastic and seldom tends to contract or become painful. Magnesium sulphate solutions are not recommended as a first dress- ing for fresh wounds, but as a curative dressing in the succeeding phase of wound repair. BIPP (RUTHERFORD MORISON’S METHOD). The name was chosen by Rutherford Morison for the sake of brev- ity and because it indicates the constituents of the bismuth-iodoform- paraffin paste. Bipp is bismuth subnitrate or carbonate 1 part, iodoform 2 parts, paraffin in quantity sufficient to make a soft paste. _ The Morison treatment, in conformity with the most advanced surgical views, consists primarily in the mechanical removal of all necrotic material and tissue detritus from the surface and interior of the wound. Blood clots, wound secretion, bacterial and other con- taminations are removed through energetic friction of all wound recesses, and after the wound has been dried with alcohol, the anti- septic paste known as bipp is spread over the wound surface. and rubbed in. The wound is then sutured, closed, dressed, and left to ‘itself for about twelve days, after which time it is expected to have healed or nearly so. Sir Berkeley Moynihan, in a recent paper on'surgical experiences in the present war, says that Rutherford Morison’s method is widely practiced in the base hospitals in England, and by many surgeons 32 {. OTHER METHODS. considered the most satisfactory of all. . This method of wound treat- ment in the opinion of Sir Alfred Pearce Gould (Brit. Med. Jour., II, 1917, p. 677) constitutes the highest attainment yet achieved. The following results have been obtained by means of this up-to- date method of wound treatment: (1) Healing of large infected wounds, without special drainage, and without change of dressings up to a period of six weeks. (2) Safe closing of such wounds by sutures, at any stage of their repair. In the opinion of Colonel H. A. Ballance, Medical Bulletin (Red Cross), March, 1918, there is as yet no reliable scientific evidence to show that “this much recommended bipp” enables a surgeon to sew up a wound successfully which without it he would have been unable to close. Bipp first came into prominence early in 1916, and in the winter of 1916-17 was a close competitor of the Carrel method in the Brit- ish army. Morison’s recent book urges most convincingly the merits of his method. FLAVINE. Flavine is a chlorine compound, with strong bactericidal proper- ties, and was originally known as trypaflavine, on account of its therapeutic effect on trypanosome infections. On its first introduc- tion into the treatment of war wounds, it was enthusiastically re- ceived, and at first highly commended, more particularly by Brown- ing and his coworkers in the Bland- Sutton Institute of Pathology | of the Middlesex Hospital, London (Brit. Med. Jour., I, 1917, p. 78). Later experiments, by Hewlett (Lancet, London, I, 1917, p. 493) showed the germicidal value of flavine to be much lower than was originally claimed for it. Moreover, this antiseptic was found by Fleming, in the research laboratory of a base hospital in France, to: have a very destructive effect on leucocytes, this effect during 24 hours being greatly in excess of its bactericidal action. Major W. Pearson, surgical specialist, in comparing the relative value of flavine with other substances used under similar conditions (using no hypochlorites or other agents for which special merit has been claimed) noted no substantial differences between flavine and the other substances, such as normal saline, boric lotion, weak biniodide solution, and cyanide gauze, in regard to the control of sepsis and constitutional signs of toxemia, but in regard to the procerses of repair, flavine proved definitely inferior to the others. “ That is to say that I found flavine not only not an excellent wound dressing but relatively a bad one,” he writes in a letter to the editor (Brit. Med. Jour., I, 1918, p. 271). On the other hand, Colonel E. M. Pilcher and Lieutenant Colonel A. J. Hull (Brit. Med. Jour., I, 1918, Ill. OTHER METHODS. 33 p. 172) point out that in the many hundreds of cases (rather more than, 5,000 at present) treated with flavine in the hospitals under the conmmand of one of them, they have found that for ease of prepara- tion and application, rapidity when dealing with large numbers of cases, early cleaning of the wounds, and abatement of constitutional reaction to absorption, flavine (and also its congener brilliant green) is an admirable application under all circumstances, but especially where surgeons are few, time is short, and wounds are many. No: skin irritation was noted in the 5,000 or more wounds under their - observation. Both acriflavine and proflavine were found by Major Robert B. Carslaw and Lieutenant W. Templeton (Lancet, London, I, 1918, p- 634) to be of undoubted value in controlling and preventing the spread of sepsis, as shown by the rapid improvement in local and general conditions. “This object having been gained, there is no advantage in continuing their use, as a condition is reached in which the reparative changes are slow, although not by any means absent. Following on the substitution, after a few days, of a. more stimu- lating antiseptic, e. g., eusol, a clean wound is obtained sooner than by any other form of treatment known to us.” ‘Comparison of action of acrifiavine and proflavine—Although the action of these two salts is very similar, there can be no doubt that proflavine is slower. The improvement in the general condition of patients is not so rapid. The formation of the fibrin membrane is not usually complete until the fifth, sixth, or seventh day in con- trast with its presence on the third, fourth, or fifth day when acri- flavine is used. Further, separation of membrane and attainment of a clean wound are also slightly delayed. The conclusions of Captain W. Parry Morgan, on the action of acriflavine and proflavine (Lancet, London, I, 1918, p. 256), are as follows: 1. Acriflavine is, as regards both its antiseptic and toxic properties, more potent than proflavine. 2. Acriflavine has a very marked bactericidal inhibiting action on streptococci and a less marked one on staphylococci, but on some other organisms its effect is practically insignificant. 3. Its action is therefore strikingly selective. 4, It has a marked but slow toxic action on the tissue. 5. This toxic action of acriflavine is not so great that when used in dilute solution (say 1:4,000) it should not make an effective appli- -cation in a dressing for a wound infected with streptococcus or staphylococcus. 6. It should be applied after the wound has been thoroughly cleansed by washing, first with a rapidly acting antiseptic lotion, such as Dakin’s soultion, and then by a normal saline. 34 I, OTHER MUTHODS. In a paper (which is the substance of an official report in Oct., 1917) published in The Lancet, I, 1918, page 370, Major W. Pearson reports unfavorable clinical observations on the effects of flavine in wound treatment, and states that since completing his observations he has entirely abandoned the use of flavine in his work. “In cases where infection and sepsis are active and uncontrolled, the use of flavine following suitable operative measures has no beneficial effect on the, subsequent progress of the case in so far as the control of sepsis is concerned. Any slight differences observed were unfavorable. In cases where sepsis has already been controlled and repair has begun flavine acts injuriously, chiefly by producing an unhealthy granulat- ing surface.” While these conclusions do not prove that flavine may not possess powerful germicidal properties in certain experimental conditions, he believes they show that its clinical use is not attended with good result. Flavine is preferred by Sir Anthony Bowlby, as a dressing with sterilized gauze, after excision has been done, before the performance of suture for the reason that it has no toxic or irritating qualities and the gauze soaked in it (and kept moist by jaconet and non- absorbent wool) does not stick to the tissues, and leaves a good surface for suture (Brit. Med. Jour., I, 1918, p. 335). Flavine, brilliant green, malachite green, and other colored pastes consisting of a greasy base and an aniline dye, enjoyed their greatest vogue for war-wound treatment during the year 1917. ‘Brilliant green, or ethyl green, is homologous with malachite green, which is benzaldehyde green and makes a bluish-green solution, more intense. than brilliant green solutions, decolorized by hypo- chlorites. Proflavine is a preliminary product in the manufacture of acriflav- ine (diamino-methyl acridinium chloride) and its preparation is therefore more simple and less expensive. The employment of flav- ine antiseptics as well as all others must be preceded by the excision of all hopelessly damaged tissue, combined with careful mechanical purification of the wound. Composition of brilliant green paste——This paste, which was in- troduced by Captain Wilson Hey in the treatment of infected war wounds, is composed of boric acid, paraffin, chalk, and brilliant green. The application of this paste is reserved for those war wounds which can be freely opened and excised, with removal of all necrotic matter and foreign bodies. Small, completely excised wounds could be primarily sutured after the application of brilliant green, in the experience of Captains Rendle Short, Arkle, and King. In war burns, under the care of Major Hull, irrigations with brilliant green lotion, followed by paraffin paste, yielded better results than any other treatment. Il, OTHER METHODS, 85 CRYSTAL VIOLET AND BRILLIANT GREEN. The use of a mixture of crystal violet and brilliant green in strong solution, for the sterilization of the skin and other surfaces, was recently suggested by Dr. C. H. Browning, director of the Bland-Sutton Institute of Pathology, Middlesex Hospital, where the method has been a part of the routine for the last two and a half years. The method rests on the theoretical consideration that these substances are both extremely potent antiseptics, and at the same time devoid of irritating effect on the skin when applied in high con- centrations. The solution in use contains 1 per cent of a mixture of equal parts of crystal violet (the substance employed should be hexa- or penta-methyl violet or a mixture of these) and brilliant green (specified as brilliant green sulphate, zinc free) dissolved in equal parts of rectified spirit and water. This violet-green mixture was found to be highly efficient, and strikingly superior to iodine, as a means of effecting both thorough and rapid sterilization of the skin. Streptococci and staphylococci are among the organisms most susceptible to these dyes. (Brit. Med. Jour. I, 1918, p. 562.) In the experience of Captain R. Massie, covering 46 cases of severe gunshot wounds in which the soldiers’ subsequent progress after wound treatment with brilliant green could be ascertained, brilliant green proved a useful antiseptic, especially in a solution of 1:500 in 0.5 per cent chloretone. It produces exuberant, but very vascular, bright red granulations. Noticeable features in cases treated with it. are the absence of edema and inflammation around the wound and the rapidity with which sloughs and sequestra separate. It is pain- less in application, and does not appear to interfere with the growth of epithelium. Although it can by no means atone for a complete or faulty primary excision it may. be used with advantage where anatomical conditions render complete primary excision impossible. (Lancet, London, I, 1918, p. 635.) HYPERTONIC SOLUTIONS (LYMPHAGOGIC AGENTS). Substances which produce a free flow of lymph from the tissues with which they come in contact, thereby indirectly flushing the wound and diluting the toxins, have been recommended in the treatment of infected war wounds by Sir Almroth Wright and his followers. A1- though the lymphagogic effect increases in proportion to the strength of the salt solution, it is not desirable, on account of the resulting pain and irritation, to go beyond 10 per cent of salt, even in the case of sloughing wounds. In order to prevent the lymph coagulat- ing on the siphon bandages, and on the walls of the wound itself, citrate of soda is employed in combination with hypertonic salt 36 Ill, OTHER METHODS. solutions. Blood mixed with pus is prevented from clotting by 5 per cent of salt mixed with 0.5 per cent of citrate of soda. For the sole purpose of irrigation and removal of pus, the citrate is unneces- sary. In order to encourage a free outpouring of lymph from the whole internal and external surface of the wound, Sir Almroth Wright pro- poses an arrangement of bandages by means of which the irrigating fluid can be led into the wound where it is required, be distributed so as to wash down all walls, and then be carried away without any leakage into the bed. Loops of sterile bandages, previously soaked in a solution of 5 per cent sodium chloride and 0.5 per cent sodium citrate are introduced into the wound, after this has first been syringed out with the solution. The free ends of the bandage are carried out from the wound, to be inserted between piles of lint well soaked in the solution and folded over so as to form a thick pad. Finally, one or two tabloids of salt should be placed in between the back layers of the pad, and over the top of all a layer of impervious protective tissue. Formula of Wright’s solution. Sodium citrate ___-centigrams__ 0. 50 Sodium chloride 2S do_.-. .380 Distilled water. grams. 100 The employment of this “antiseptic anodyne” yielded excellent results in the experience of Dickinson, who has used it for two years in all sorts of cases, the wounds remaining clean and healing more rapidly than under the use of any other liquid. Sir.Almroth Wright says with regard to this lymphagogic solu- tion, or rather with regard to a simple 5 per cent salt solution, which he finds works in most cases equally well, that it has in this war proved itself permanently useful. When brought into action upon a dry and infiltrated wound, or a wound that is foul and covered with slough, it resolves the induration, brings back moisture to the sur- faces, and cleans up the wound in a way that no other agent does. Applied in gaseous gangrene in the form of a wet dressing to in- cisions which have been carried down into infected tissues, it causes lymph to pour out of the wound, and arrests the spread of the infec- tion. And, again, applied in gaseous gangrene to an amputated stump in cases where it has been necessary to leave infected tissues behind, it reverses the lymph stream and draws out the infected lymph, saving life in almost desperate conditions. The activity of salt solutions depends on this “phylacagogic” character, meaning their capacity for bringing the protective ele- ments of the body, blood fluid and leukocytes, into activity in the wound. Ill OTHER METHODS. 387 SUNLIGHT TREATMENT OF INFECTED WOUNDS. Heliotherapy, or sunlight treatment of war wounds, deserves to be more extensively employed as a physiological curative method, the routine adoption of which is urged by Dr. M. Cazin (Monograph, Paris, 1917) as a measure capable in many cases of greatly abridging the duration of the treatment of war wounds and essentially reducing the number of war invalids. Sunlight treatment, first recommended by Rollier in tuberculosis and traumatism, is most successful when the patients are exposed nude for many hours to the rays of the sun. Although total insolation is always to be preferred, local insolation with a graded action of the sun on the course of the wounds materi- ally assist the processes of repair. The exposure to the sun must be direct, and in the open air, in order to improve nutrition and promote oxidation, and total, including the entire body, the resistance in- creasing in proportion to the extent of the insolated surface. In- solation of the clothed body is cautioned against as liable to induce visceral congestion. The insolation method should be carried out progressively, always beginning with the less: sensitive lower extremities, even when the wound concerns the thorax or an upper limb. Aside from the analgesic action of the sun bath, its local effect promptly induces a change in the condition of the wound. In the second stage of the treatment, about the eighth to tenth day, the sup- puration diminishes, after having notably increased following the first sessions, and healthy granulation tissue develops; the wound becomes dry and clean, its borders retract, and a zone of epidermi- zation makes its appearance. Constant phenomena in the sunlight treatment of wounds are regional pigmentation, a change in the character of the pus, and an abundant serous exude over the entire surface of the wound, which soon dries up more or less completely. In the experience of Cazin, atonic and indolent wounds, on ex- posure to the sun, became regularly covered with a layer of healthy granulations, and in other wounds without an apparent tendency towards epidermization, an epidermal margin promptly appeared at the borders and advanced without arrest toward the center of the wound. Sunlight treatment was found to hasten recovery, not only in wounds of the extremities, but also in wounds of the thorax and ab- domen. Excellent results were obtained in infected fractures, and in several cases where the bony lesions were such as to endanger the pres- ervation of the limb, heliotherapy led to complete consolidation and perfect recovery. Some cases of infected fracture of both leg bones healed in a few weeks under sunlight treatment, after the condition had remained stationary for months, in spite of repeated interven- 38 Id. OTHER METHODS. tions and all other treatments. The results of heliotherapy were equally favorable in joint infections, and in the cicatrization of am- putation stumps with bony fistulas. In Delbet’s service, all wounds are exposed daily for as long as possible to air and light, covered only with a fourfold layer of gauze without cotton or bandage. Very remarkable results were obtained with this simple treatment. Gravely infected wounds which yielded a highly positive pyoculture became transformed, so that in two days the pyoculture became entirely negative. In one instance, the wound secretions became in 48 hours not only bactericidal but bac- teriolytic for the vibrio. This simple plan of wound treatment is warmly recommended by Delbet (Presse médicale, XXIII, 1915, p. 237). Artificial light, in the form of electric lamps, is always available, and in the experience of Chaput (Presse méd. XXII, 1914, p. 606) was found to be as valuable as the sun bath for local use in burns. . and ulcerations. An ordinary electric lighting outfit provides a simple, cheap, practical and highly efficient method of treating in- fected or gangrenous wounds, and it is suggested that this mode of treatment may find its uses in certain complications of war wounds. PHENOLISATION AND EMBALMMENT OF SEPTIC WAR WOUNDS. (Menciére’s method.) The modern spirit of conservative surgery is embodied in the embalming method proposed by Dr. L. Menciére, the Médecin-Chef of the Hépital de la Compassion in Rheims, in 1916. A part of the Grand Palais is used as a hospital, and here I found this method of septic wound treatment extensively employed, although in no other place that I visited did I find it used. Dr. Menciére has published a book, which is most interesting, with pictures and statistics of cases. I append hereto pictures of two of his cases. By phenolisation is meant the subjection of infected war wounds to the energetic action of strong carbolic acid (90 per cent) fol-' lowed by washing out with alcohol. Reinfection of the cavity is most reliably: prevented by the so-called embalmment of the wound, which consists in permanent dressing with gauze wicks soaked in the following powerful antiseptic solutions: Solution A. Grammes. Iodoform 10 Guaiacol oe S Sie Seca s eRe eee 10 ¢ Hucalyptol 10 Balsam of Peru 30 Ether. : ‘100 A weaker solution, B, consists of ether, 1 liter; iodoform, guaiacol, eucalyptol, of each 10 grams, balsam of Peru, 30 grams; and alcohol * (a) (b) April 29, 1916, shell splinter wound, left foot: (a) May 20, 1916, photograph of left foot; (b) June 22, 1916, photograph of left foot. July 25, 1916, walked normally, without a cane; had all movements of hip, knee, and foot. qi) (2) (3) Wounded March 2, 1916. Admitted March 5, 1916. Muscles torn otf by explosion of '' Minen- werfer.”’ (1) Photograph taken March 10, 1916; (2) photograph taken March 19, 1916; (3) photograph taken April 2, 1916. 38 Ill. OTHER METHODS. 389 (90 per cent) 100 c.c. The results obtained with these antiseptic solutions were superior in Menciére’s experience to practically every- thing else. Phenolisation and embalming of war wounds is advocated by the originator of the method on the basis of favorable experience in wound treatment including the gravest articular traumatisms, and . especially in the treatment of gas gangrene. The performance of primary suture, immediate or delayed, is often made possible by the employment of this procedure. About 24 primary sutures of bone and joint wounds, with a successful outcome, after systematic ex- temporaneous wound embalming, were reported by Gaudier at a meeting of the surgeons attached to the Sixth French Army (Soc. de Chir., February 1916). Preservation of badly wounded extremi- ties, and application of delayed sutures, were made possible in a relatively large number of soldiers apparently doomed to amputa- tion. - 7* ELECTRICITY. Galvanic, faradic, and static currents are used extensively in the treatment of scars and devitalized tissue resulting from wounds and other war injuries. Lately, the high frequency current and ultra violet ray have been recommended by Riviére of Paris and a number of others. Dr. Riviére showed me some of his work, and urges as follows: Judicious employment of the high frequency current, also known as Darsonvalization, is a valuable adjunct in war surgery, constitut- ing a potent physiotherapeutic measure for the regeneration of tissues, nerves, and blood vessels. Due to its practically pure content of violet rays, without admixture of heat radiations, this high- frequency treatment exerts a most favorable effect upon cicatrization, besides producing a deep local anesthesia. To this is added the oxi- dizing and antimicrobic action of the generated ozone, through which the wounds become enabled to resist bacterial invaders. At the same time the ozone, by stimulating the capillary circulation, ensures a beneficent absorption of tried and tested remedies, such as various mineral oils and balsams, iodides, salicylates, etc. The condensed and electrified oxygen stimulates phagocytosis, furthers the forma- tion of red blood corpuscles, and improves the nutritional condition — in the surroundings of the lesion. For the treatment of certain very slowly healing infected war wounds, Riviére, on the basis of favorable experience with a number of cases, suggests the combination of the high-tension current with the most reliable antiseptic balsams; these are atomized by the high- frequency current and superoxygenated through the condensation of ‘the ozone and the static breeze. 40 Ul. OTHER METHODS. OXYGEN AND OZONE IN WAR WOUNDS. Wound infections and gas gangrene have, in certain cases, been markedly benefited by oxygen-therapy, and aside from older reports, the experience of the present war, although not unanimous, points” in the same direction. In the hands of Vennin, Girode, and Haller (Phipps, Thése de Paris, 1916) oxygen, in the form of injections into the healthy parts, prevented the onset of gas gangrene in badly infected wounds caused by explosive projectiles. In other cases of manifest gas gangrene, but in which the infection was restricted to the wound and its immediate surroundings, its spread was effectively aborted, and when swelling and bronzed discoloration had already invaded the limb, the process was successfully arrested provided no gangrenous patches had developed. Finally, even when the limb was invaded by the putrefactive process, the destruction was successfully limited in certain cases, and in this way a number of lives were saved. Fourteen cases are reported in support of this line of argumentation, and one of these is quoted as especially illustrative of the severity of the infection and the excellent results. Soldier, shot at short range; comminuted fracture of the humerus, at the level of the upper third, with explosive lesions. The limb promptly became infected, and the gas infiltration soon reached the shoulder, with invasion of the deltoid, pectoral, and part of the supraclavicular regions. Oxygen injections were applied at the root of the limb, the adjacent portion of the thorax and the correspond- ing side of the neck. Difficulties were encountered in the form of respiratory disturbance due to the tissue-inflation, and the patient’s condition appeared desperate. The oxygen injection was repeated the next day, the condition remaining stationary. At the end of another day there was decided improvement, the extension of the gangrene at the root of the limb was definitely checked and a line of demarcation appeared at the level of the fracture in the deltoid region, in the gangrenous area. Improvement continued during the next days, the cleansed wound assumed a good appearance and healthy granulations developed. The patient was evacuated as a convalescent. It is not claimed that the oxygen method should be employed in war wounds without the assistance of free incisions, or amputation if unavoidable. In Belgium, oxygen has been used to inflate the tissues above and below the wound area to limit infection. It has been extensively employed in gas gangrene by Depage (Bull. et mém. Soc. de chir. de Paris, March 23, 1915, p. 697), who found these in- jections highly serviceable in the presence of septicemia with sub- cutaneous gas infiltration. The oxygen spreads under pressure in the entire subcutaneous cellular tissue and checks microbic growth wherever it penetrates. Remarkable changes follow its employment Ill. OTHER METHODS. ‘41 in the more superficial cases, but when the infection is deep and has invaded the deep cellular tissue of the thigh, buttock, back, or shoulder, the action of the oxygen is-necessarily reduced, and the result of its application rendered more doubtful. . Hydrogen peroxide is hard to get but is much favored and con- sidered valuable in sloughing septic wounds. Ozone treatment of war wounds is a very recent innovation, recom- mended on the basis of the satisfactory results obtained by Major George Stoker, of the Royal Army Medical Corps (1917). The necessary portable apparatus for generating ozone employed by him is known as the Andriolis ozonizer, which is called into operation by a four-volt battery animating a quarter-inch sparking Ruhmkorff coil. The oxygen passes from a cylinder through the ozonizer, and.in doing so comes in contact with a metal armature, the effect of this being to transform the oxygen into ozone. The treatment consists in the application of ozone to-the affected parts. At first ozone causes an increase in the discharge of pus; later on the pus is replaced by clear serum, which at.a still later stage becomes reddish or pinkish. Ozone has the peculiar power of disclosing dead bone, foreign bodies, septic deposits and so forth. Mode of application—The ozone is applied on the wound surface or to the cavities and sinuses for a maximum period of 15 minutes, or until, the surface becomes glazed. It is a strong stimulant, and causes an increased flow of blood to the affected part. It is claimed to be so strongly germicidal that all hostile microorganic growths are destroyed. _Acetozone, or benzoyl-acetyl-peroxide, is a powerful disinfectant of the same group having a remarkably pleasant pungent. odor of ozone. It-can be applied to deep: wounds by Carrel tubes or used cold as a bath containing 5 grains to the pint; in a waterproof bag; or by, wet: dressings of 10 grain strength solution, renewed two or three times daily. The solution. must be made by adding 5 to 7 grains to 1 pint of sterile water at 112. F., left to, stand for two hours, and should not be filtered... Ora 10-grain to 1-pint solution can be used with dressings or Carrel-Dakin tubes, etc.. In very septic cases swarming with anerobes, etc., a 20-grain to 60-grain solution may be used. It. should be made fresh every seven days, and the bottle shaken before using. In the experience of Gore Gillon and others, numerous septic wounds healed in three weeks. under this treatment, after having resisted. other measures for four or five months., The action of this germicide is very rapid, and it is claimed that. unhealed amputation stumps will heal quickly if placed for 30 minutes daily i in a bath of a: 7-grain | solution. with one-third hot water added, the bath to. be followed by dressings of sterile gauze soaked in.a 10- -grain solution. (Brit. Med. Jour., II, 1917, p. 209.) . 93696—19—4 42 Ill. OTHER METHODS. From the historical viewpoint, it is.interesting to note that over 50 years ago, ozonoscopes were installed at Metz, Versailles, and Paris, for the purpose of determining the chief peculiarities of air in inhabited places, and the very suggestive findings are reported in an essay by Gaillard, which was awarded the Fiske Fund premium of the Rhode Island Medical Society, in June, 1861. “ The’ instru- ments, placed in the halls or wards of hospitals give no trace of ozone, whilst placed on the exterior of the buildings they manifested hues corresponding to degrees 7,:8, and even 10 of the ozonometric scale. These hospitals were in the most cleanly and perfect condition, well-ventilated, and manifested no perceptible odor on entering them. Ozonoscopes were placed in the halls for the wounded on the ground floor and in rooms where the windows were opened twice a day, and in which were placed not more than 18 or 20 patients. In the wards for the venereal and fever patients, where the same influences ‘existed, ozonoscopes were placed also, the hygienic relations being equally good, and the thermometer’ in all instances not exceeding 60 F, Rooms were also selected for these experiments, where the windows were kept always open (by day). The ozonoscope, judiciously’ ar- ranged in all of these places; remained in situ for 15 days, and ex- hibited no change Sa there being not-even a trace of ozone present.” The part reserved fon ‘oxygen and its congeners in the fight against infection was foreshadowed prior to the war, and 10 years ago, my own investigations dealing with'the use of oxygen by infusion into the peritoneal cavity proved So encouraging as to cause me to con- tribute an article on its use in medicine and surgery to an American periodical, and this has been quoted as one of the sources of informa- tion of a very recent French thesis on the subject (Phipps, De Vemploi en therapeutique chirurgicale de oxygéne 4 Vétat gazeux, 1916). My own experience at the time led me to anticipate the results which the experience of to-day seems to establish. The de- fensive forces of the organism beiig peculiarly weakened for a va- riety of reasons against the infections of war wounds, it seems espe- cially desirable to secure a therapeutic agent which will not exert an injurious action upon the tissue cells. Oxygen, as a matter of fact: far from damaging the cells, has been shown to stimulate cel- lular activity, to activate phagocytosis, and to favor all defensive reactions, such as diapedesis and secretions. Aside from its effect on anaerobes, it has no direct destructive action upon microorganisms, but by stimulating the activity of the natural defensive forces, it furthers the power of resistance and in this way becomes a valuable physiological assistant in the fight against infection, upon the win- ning of which depends the success of surgery in general, and of war surgery in.particular. TREATMENT OF WAR WOUNDS BY THE GERMANS. The lessons of war can not be adequately determined until long after the conflict ends. This is due largely to two factors which are, first, the heat of passion which must have time to cool sufficiently to permit the forming of correct judgments, and, second, the lack, of _ authentic data from both sides. In our search for those, lessons which may aid us along medical and surgical lines, the first of these factors may be eliminated, but the second remains, largely as an intentional barrier set up by the enemy. Germany is making and has made a systematic effort to prevent the leakage of dependable information relating to military medi- cine and surgery. During a half century of preparation for war the Germans had perfected an organization of ambulance and. hos- pital service, nicely coordinated with the military branch and equal to it in efficiency. They apparently believe that this organization is superior to that of the enemy, and that an interchange of exper- iences which might.tend to prevent suffering and to save life and. limb would not be to their particular advantage. This is consistent with their philosophy but devoid of the first elements of humanity. ‘ The severance. of postal communication with Germany ‘since our entry into the war, her systematic attempt to prevent trust- worthy information from reaching us, and her dissemination of misleading statements prevent us from ‘obtaining full knowledge concerning her progress. in military medicine and surgery, but in spite of these barriers there are a few facts relating to her methods and results which we have established from our present. sources of information. These are perhaps more valuable by way of compar- ison than as affording any actual addition to our knowledge. . During the summer and fall of 1915, I was privileged’ under ex- ceptional auspices to make a hospital, Red Cross, and sanitary sur- vey through Holland, Germany, Switzerland, and back to the United States by way of France and England: In Germany we were to all appearances received cordially and shown what we desired to see, but it was soon evident that we were even then looked upon in many quarters as future enemies. We were shown what they wished us to see and told only what they were willing we should know. All that we learned could, I felt, be no real basis for generalization, but there must be continnation and very careful weighing of the whole before any deductions could be drawn. : 43 44 CONDITIONS IN GERMANY LATE IN 1915. The sources from which the following was obtained were: 1. Personal observation during the trip. 9. Discussions with those who had been at work in Germany since the beginning of the war, including representatives of the American Red Cross, Y. M. C. A., sanitary agencies, etc. 3. Contact with neutrals or Germans in Holland and Switzerland, 4, Examination of German prisoners in allied camps. 5. Articles in neutral scientific papers. 6. Such books or articles as have been allowed to get through from Germany. 7. Statements by workers in advanced areas at the allied front where the swaying backward and forward of the line often reveals the medical and surgical secrets of one side to the other. CONDITIONS IN GERMANY LATE IW 1915. The ambulance and hospital organization at that time was ex- tremely efficient. All had been made ready, and there was indubit- able evidence that for years they had clearly foreseen and provided for what was coming. A good example of this forethought was a ' pavilion hospital at Buch, on the direct line from Berlin to the eastern front. This hospital of 6,000 beds was beautifully situated in the country 40 minutes by express from Berlin. It was already fully equipped for 3,000 patients a few weeks before war was de- clared and it contained 4,000 patients at the time of my visit. A small railway system connecting the main line with each set of wards made it possible for the wounded entrained at Warsaw to remain undisturbed until their arrival at the entrance of the particular ward to which they were assigned. The most modern methods were em- ployed here, and there was even a special department for gassed cases. This is particularly interesting when the dates are noted, as showing that they were prepared in advance to treat this class ae cases, The equipment throughout was superb and included electrical and mechano-therapy departments, baths of all kinds, a gymnasium with special apparatus for the mutilated, a recreation park, and. a theater, seating 600, for plays and moving pictures. Here they showed scenes of peace and pictures of other lands, including, for example, the Yosemite Valley and Niagara Falls; and here also the latest news, always encouraging and patriotic, was flashed upon the screen. ‘A special feature was the continuous bath ward. Here they treated those patients, who, on account of wounds of the back or, in cases of paralysis, for fear of bedsores, could not remain even on the water bed. Some of the patients had been in the bath for months. This method was also being tried out in cases of septic wounds. Hospital in Buch. Kriegs Lazarett, Buch, Kriegs-Lazarett der Stadt Berlin in Buch, 44—2 Patient in continuous bath doing industrial work. CONDITIONS IN GERMANY LATE IN 1915. 45 Aside from the strictly medical care of the patients, their mental state was carefully considered, on the principle that “the more hope and courage, the better the healing and the shorter the convalescence.” At the earliest date possible patients were urged to do something to occupy their minds and if possible to learn at the same time a trade. The patient shown in the accompanying illustration was suffering from paralysis below the waist and had been six months in the bath, but was learning to do some work with his hands. We were shown large amounts of food supplies being accumulated, including great quantities of American canned and dried foodstuffs. Evidently the blockade was not very effective up to that time. In Berlin we saw the central sanitary laboratory, a very large and splendidly equipped building where the various vaccines for the army: were prepared. A professor of the university was in charge, and the following statements which he made to us may be of interest in this connection: We give as a routine three vaccinations, practically all at the same time— for smallpox, for cholera, and for enteric fever. Each man throughout the entire German army now has these three. .The cholera vaccination is the most effective. We have had no cholera. The smallpox vaccination comes next and is highly protective. The typhoid vaccination has been wonderfully suc- cessful in preventing this disease, but there have been a few cases. The tetanus vaccine is protective in a considerable measure when used in wounded cases, but after the onset of the disease it is of very little, if any, value. In these cases I use magnesium sulphate intraspinally. This is coming into gen- eral use and is often proving successful in the active stage. Other vaccines than the four alluded to are not of any real value. . At Cologne there i is a military hospital of 2 ,000 beds, an enlarge- ment. of a smaller hospital connected with the university, where, at the time of my visit, there remained only one student. They have here a large physicotherapeutic, department with. all, kinds of elec- trical apparatus, X-ray equipment, Finsen light, and i many mechani- cal devices for special exercises. Before the war Germany. had adopted, a policy of far-reaching et- fect. The establishment of a gymnasium with baths and a physi¢o- therapeutic institute in connection with a certain large hospital had proved of great benefit to the patients; in fact, considered as an eco- nomic measure alone, it had been found worth while. So for years such departments have been established in connection with many of the hospitals throughout Germany, as well as in various hospitals founded by Germans in other countries. ‘When war ‘started these be- came of double value, inasmuch as they, were ready to give special treatment of all kinds to the war wounded. We have had to introduce these very things, after much delay, and are only now really making a good beginning. In July, - 1917, when the plans for enlarging the Brooklyn Naval Hospital were bene dis- 46 CONDITIONS IN GERMANY LATE IN 1915. cussed, at the request of Captain G. A. Lung, Medical Corps, United States Navy, commanding officer, I drew up and submitted a paper entitled “Some Medico-Military Suggestions,” embodying much data on this subject, based upon my observations in Germany. We found many of the private hospitals had been taken over and were being operated as military hospitals for officers. The only hos- pitals: we saw which we could really criticize were those. in Paee camps, as at Darmstadt. - The wound treatment then in use consisted in early long i esata free drainage, and strong antiseptics, with invariable early splinting of fractures and immobilization of wounded parts. Their expert surgeons were stationed well'up in the forward areas, so that they could decide what was to be done in each:case. This method gave ex- cellent results, since it enabled the wounded men to have the best ad- vice at the time when it was most needed. Severe abdominal wounds and head injuries were rarely moved back and early treatment was instituted at the front in all cases in which it was thought advisable. « Since 1915 it has become increasingly difficult, for the reasons al- ready noted, to secure any reliable information relating to military medicine and surgery in Germany. It has been possible, however, to. verify certain facts bearing on this subject, which are herewith presented. , In Germany, no one method of controlling wound infection seems to have been adopted to the exclusion of competitive procedures, as on the side of the allies, where the Carrel-Dakin method of wound treatment has been so largely adopted. Although irrigation with dilute antiseptic solutions is employed by German surgeons, opin- ions vary widely as to the value of antiseptic agents. Irrigation with hydrogen peroxide has been extensively used in their military hos- pitals and is claimed to be especially efficacious in the treatment of infected fractures. Brun, writing in one of the leading German periodicals (Deutsch. Zischr. f. Chir., vol. 183, 1915) advocated the use of the following so- _ Intion, with shiek he claimed to secure very satisfactory results: Oleum(Olivar,. ste@vilo 2.2520 cen 2 nee ee eee Be ee ore bees 100 ENGR ke eet ee ln Spe oe Sette 100 Tlodoform.......-.----------+--.--- ee 4 sae a wii aoe aes See SaaS 10 'Todine 2 may be substituted for iodoform if desired. In using this solution the surrounding skin should be painted with iodine, the wound cavity drawn well apart with hooks, and the solution then poured in so as to penetrate all the recesses. The wound is then loosely covered with gauze, which is fixed in place by means of mastic, and the limb i is immobilized. CONDITIONS IN GERMANY LATE IN 1915, AT Vernisanum purum, a combination of iodine, phenol, and camphor, has also been recommended as an especially valuable antiseptic in war surgery. In 1916 a hemostatic antiseptic consisting of a solution of iodo- form in acetone, was introduced into Germany. This is applied to the wound by means of gauze strips dipped in the mixture, and the burning sensation which follows its use in wounds of the skin and soft parts is controlled by the applications of compresses dipped in 1 per cent acetone-soda solution. The iodoform-acetone solution di- minishes the wound secretions and stimulates the formation of healthy granulations, but its most valuable property consists in its prompt action as a hemostyptic in parenchymatous hemorrhages, especially from’ porous bones.” (Miinchen med. Wschnschr. Feld- aerztl. Beilage, No. 48, 1916.) Various chlorin-containing substances have been in use since early in'the war, calcium hyperchloricun: having been perhaps the most extensively employed.. This has been used in a 1 or 2 per cent solution for bathing and irrigating wounds or, in combination with animal charcoal, magnesium sulphate, and bolus alba, as a dusting powder. In January, 1917, the Correspondenz-Blatt fiir Schweizer Aerzte, a Swiss periodical published in the German language, in an abstract from French original sources, brought the Carrel method of ireating infecting war wounds to the favorable attention of its readers. ' Other antiseptics.advocated by German surgeons include Karlsbad salt; leukozon, a mixture of equal parts calcium perborate and talc; pellidol, a substitute for scarlet-red; liquid tar, etc. In opposition to the antiseptic method of wound treatment, and in analogy with the physiological lymphagogic method indorsed by Sir Almroth Wright, some German writers on early wound treatment at the front have proposed the use of nitric salts, which on coming into contact with organic substances are at once reduced to nitrous salts. The object aimed at is to increase the hyperemia in these in- variably infected war wounds, and to produce a free flow of lymph. Muller, writing in the Mtinch. med. Wschnschr. Feldaerztl. Beilage. No. 27, 1916, expresses himself as well pleased with the results of this “ abortive” treatment of gunshot wounds, although it necessitates a frequent change of dressings. After the wounds have been incised and foreign bodies removed, he introduces into the wound cavity cotton wool soaked in silver nitrate solution (1:2 000) and wrapped in gauze. The permanent irritation thus induced in the wounds leads to the rapid detachment of nonviable tissues, usually with a rise of temperature due to absorption of toxins. For fixation of the extremities in fracture cases, German surgeons make extensive use of Cramer’s wire splint and Volkmann’s T-splint, 48. CONDITIONS IN GERMANY LATE IN 1915. femoral fractures being usually treated with extension apparatus. Plaster bandages are considered as unsuitable where a frequent change of dressings is required. Repeated plastic operations on the mouth and nose are recom- mended in the treatment of glancing gunshot injuries to the facial region. Soldiers with injuries of the jaw are transferred as soon as possible to the dentist for orthodontic treatment. _ Germany has given considerable attention to the after care of the wounded soldier, with a view to returning him to the ranks if possible, or, if he must be sent back to civil life, making him self supporting and not a burden to the community. In an article published in 1916 (Med. Klin., April 16, 1916, No. 16) Prof. H. Spitzy describes some of the work being done at the Orthopedic Hospital in Vienna. Here between three and four thousand wounded are under treatment at one time. Mechano-therapy; hot air, steam, electricity, massage, etc., are used whenever indicated, and when a joint is certain to stiffen great care is exercised to obtain fixation in such position that it will be of the most use to the patient in the future. Occupation therapy is used to its fullest extent, 30 different occupations being taught. In order to restore the disabled men’s working capacity to the utmost, soldiers who have lost an upper extremity are usually equipped not only with an arm prosthesis, but also with a set of different attach- ments, up to 20 or more, according to the requirements of the various occupations. __An interesting fact, possibly bearing on economic.as well as surgi- cal conditions, is that in 1915 and 1916 sawdust was being used as a dressing for many wounds, instead of cotton. This was called “scobitost.” . -Dr. H. M. Richter, of Chicago, who was for six months in 1916 in charge of a German base hospital has published. an article, covering his work at that base, which he summarizes as follows: Recent injuries are best treated by wide excision of the wound, including all contused, and soiled tissues, and immediate closure. This applies with greatest force to the larger joints quite as well as to the wounds of soft tissues. Im- mediate antiseptic treatment of wounds, with free drainage by means of tubes or gauze pack, ‘{nvariably results in infection though the infection. remains localized in proportion to the adequacy of the drainage. Carrel’s treatment has been successful in relatively few hands; The numer- ous details to be observed in the preparation of the solution and its ee probably offer an insuperable obstacle to its general use. The open, treatment of infected wounds forms the simplest ana “most con- venient method of handling patients in large numbers. The routine tubbing of patients with infected wounds, irrespective of the parts involved, gives remarkable and instantaneous comfort to the patient, and controls suppuration more rapidly than any one method at our disposal, its field of usefulness being limited only by lack of facilities, under ordinary mili- tary conditions. CONDITIONS IN GERMANY LATE IN 1915. 49 Nonunion in fractures, simple and compound, clean or infected, rarely oc- curs where the interposition of tissues is prevented and no foreign bodies are left in the wound. Compound fractures into the larger joints, present a high rate of mortality, only partly controlled by wide open drainage and resection. All larger shell fragments must be removed. Stereoscopic roentgenography, aided by the proper placing of markers and the insertion of probes along the track of the missile, forms the best means of locating foreign bodies. In closing this section it may be of interest to point out two con- trasts which must strike forcibly any one who is conversant with the facts The one contrast lies between the marvelous efficiency of Germany at the outbreak of the war and the conditions, best de- scribed as chaotic, which existed at that time among the allies. The other contrast, more gratifying to us, is shown when we compare those same conditions with the truly. wonderful improvement to be found today on the side of the allies. . DEVELOPMENTS IN WAR SURGERY. ANESTHESIA. War surgery is demonstrating more clearly than has ever been appreciated in the past, the close relationship between anesthesia and the extent of mortality and morbidity. Major Marshall, who has been for over three years in a casualty clearing station in an active part of the forward area, summed up for me his experience by say- ing that the bulk of preventable deaths ata casualty clearing station was due to improper anesthesia, “giving the wrong anesthetic, or giving the right anesthetic wrongly.” As a result. of this realization, new methods are-being devised and old methods improved upon by those actively engaged in war surgery. Chloroform has been rather generally discarded, although many surgeons still employ it and feel safe in its use. As a pre- liminary to the general anesthetic, morphin and atropin or omnopon, with or without scopolamine, are often used. Ethyl-chlorid as a pre- liminary or for short cases has some advocates. The various types of anesthesia that have increased in favor and the newer methods that are receiving consideration are: 1. Local and regional anesthesia. 2. Gas and oxygen (with or without ether). 3. Oral anesthesia. 4. Spinal anesthesia. 5. Rectal anesthesia. Local and regional anesthesia—This method is being extensively used in many centers, either alone or combined with light general anesthesia. At various hospitals, I saw it successfully employed in cases involving major operations, such as laryngectomy, trephining, amputations of the thigh and leg, and transplanting of bone and cartilage successfully. It is obviously valuable in many kinds of war surgery. Gas and owygen.—The sequence of gas and oxygen, alone or com- bined with ether, has steadily gained in favor and bids fair to be the method preferred where local anesthesia is not applicable. The work of Crile, Gwathmey, Marshall, and others who have had a large experience with desperately wounded cases seems to establish this method as lessening mortality and reducing morbidity. Without ether, it is especially valuable for abdomen, chest, and abdomen with. chest cases. Open ether is dangerous in chest cases, and local anes- ' 51 52 ANESTHESIA. "i + thesia or gas and- oxygen without ether are favored. No gassed (inhalation) case should have either chloroform or ether. Moynihan and some others believe that for full relaxation, especially in cases of laparotomy, a preliminary hypodermic is necessary and the addi- tion of ether. Until recently, the various types of apparatus for the use of gas, oxygen, and ether, especially those which warmed the vapor, were most complicated and expensive. In spite of these drawbacks, in- creased numbers were being put into use in the hospitals of the allies. Fortunately, the American Red Cross in France, through the work of the staff of its chief surgeon, has recently devised a simpler and far less expensive apparatus, which seems destined to have a - large field of usefulness. Already considerable numbers have been ordered for the American expeditionary force. In the selection of a standard apparatus for the United States Army and Navy, the following requirements must be borne in mind. It should be: 1. Simple; no complicated parts to get out of order. 2. Efficient; in supplying continuous flow of gases at uniform pressure. 3. Inexpensive; in order to permit of the gases being administered to every case requiring them. An English Hewitt apparatus, or some modification, falls short of meeting the requirements in that it depends upon rubber bags for the reduction of pressure, and is therefore inaccurate in this respect. The many types of American apparatus depend usually upon re- -ducing valves weighing from 5 to 15 pounds. Some ‘have as many as four reducing valves to each apparatus, while most of them have a separate bag for the nitrous oxide and the oxygen, respectively. Furthermore, they are all provided with a clock dial or indicator to show the rate of consumption per hour of the respective gases. They all fall short of the first and third requirements. The American Red Cross apparatus—The use of needle valves reduces the gases as effectively as the usual large reducing valves, the weight, size, and cost being at the same time decreased to one- fourth that of any other suitable and efficient apparatus. The weight is estimated to be about 8 pounds and the cost about 125 francs. The sight feed (i e., two tubes immersed in water contained in 2° ‘glass bottle for the nitrous oxide and the oxygen, respectively, the bubbles made by the gases escaping from the holes in these’ tubes in- dicating the approximate percentage) replaces the clock dials and indicators. The first hole in the oxygen tube is approximately 5 per cent by volume of the four holes in the nitrous oxide tube, which is the usual proportion with only slight variations for individual patients. Apparatus for anesthesia, 52 ANESTHESIA. 58 Furthermore, only one rubber bag is required, the space in the glass bottle above the water being utilized as a mixing chamber for the gases. There is an ether chamber attached to the sight-feed appa- ratus which permits of the giving of varying percentages of ether according to the relaxation desired. The patient is the final index irrespective of apparatus (if eyanosed, more oxygen is needed, if too lightly under, nitrous oxide is indicated) ; therefore an even flow of gases with an approximate and dependable percentage is all that is necessary in an apparatus. The possibility of breakage is greatly reduced by the fact that the needle valves and sight feed are placed immediately upon the tanks. The gases are conducted from the sight feed by two to three feet of rubber tubing to a rubber bag, which is placed near the patient’s face in order to reduce the respiratory effort to a minimum. All authorities are agreed that an unnecessary burden would be placed upon some patients if rebreathing were entirely eliminated. Tanks of nitrous oxide and oxygen adopted by the American Red Cross contain 3,840 kilos each, one nitrous oxygen tank being suf- ficient to anesthetize 100 patients, and one oxygen tank sufficient for 200 patients. Thirty-two kilos of nitrous oxide and 10 kilos of oxygen are sufficient for one patient in military surgery. The height of the tanks is 56% inches; circumference 294 inches. Weight of the nitrous oxide tank (gross), 186 pounds; weight of the oxygen tank (gross), 143 pounds. Captain Gwathmey, Medical’ Corps, United States Army, suggests that if a large tank is impractical for use in the Navy, a 2,000-gallon tank, 36 inches high, be used, instead of the 4,000-gallon tank, 60 to 70 inches high. The smaller sized tank will be sufficient for 50 patients. Oral anesthesia, or general anesthesia by oral administration.— This is among the newer methods employed in hospitals and casualty clearing stations. It was introduced by Captain James T. Gwathmey, Medical Corps, United States Army, in conjunction with Captain Howard T. Karsner, Medical Corps, United States Army. From the favorable results recorded by them and reported to me by others who are employing it on the British front, the future use of this method in surgery seems assured. While in France I discussed the subject at length with Captain Gwathmey and saw some of his work. For the sake of brevity, however, the following is taken from his report on the subject, printed in the British Medical Journal of March 2, 1918, and in the Journal of the American Medical Associa- tion of April 6, 1918. Captain Gwathmey calls attention to.the fact that many war wounds are accompanied by fractures of bones, and the importance of keep- ing the patient quiet during the dressing of wounds is obvious. He 54 ANESTHESIA. finds that a preparation containing 50 per cent ether in liquid petro- latum or other bland oil, administered by mouth, is a safe general analgesic, has apparentiy no deleterious effects on the stomach and is not followed by the nausea and vomiting that frequently accom- pany inhalation anesthesia. It may be given without unpleasant taste when “sandwiched” between mouthfuls of port wine., The patient does not need to be taken from his bed, thus reducing the pain and the danger of displacing bone fragments before and after dressings, and saving the time of surgeons, nurses, and orderlies. Supplemented by local or light inhalation anesthesia, or a hypo- dermic of morphine; when necessary, the method is being developed to embrace short. surgical operations. While it is well not to give the analgesic immediately after a meal, no especial preparation of the stomach is necessary, and the patient is able to take food and water shortly afterward. Captain Gwathmey and three messmen tried the oral analgesic successfully. He now uses the following formula: Peppermint Walls cone nae ean te ee ese eee dees 5 minims. Ether. . oo, . oeoes 4 fluid drachms. Tid. paraffins 22sec Se es eee 4 fluid drachms. The report describes a number of cases which were dressed in No. 9 (Lakeside U. S. Army) General Hospital, among them the fol- lowing: Case 1: A soldier, aged 36, who had received a gunshot wound of the right thigh, and had an infected, compound, comminuted_ frac- ture of the femur, had found previous dressings very painful, and the splint could not be changed without general inhalation anesthesia. He was given paraldehyd, 1 fluid drachm; ether, 3 fluid drachms, and liquid petrolatum, 4 fluid drachms. ‘In 15 minutes he fell into a light sleep. The wound was dressed, the splint removed, the through-and- through wound irrigated with ether, a gauze drain inserted down to the femur and a Thomas splint applied with extension. The patient talked during the dressing, felt practically no pain, and suffered no nausea or other unpleasant after effects. The dressing was repeated in a similar manner every other day for four dressings, and in none of them was there pain or any alternation of pulse or respiration. Case 2: A soldier, aged 28, who had a gunshot wound of the left thigh, with a compound comminuted fracture of the femur, was given the same mixture as in case 1. He feel asleep after 12 minutes, The Thomas splint was removed and replaced, the gauze packing re- moved, the wound irrigated with ether, and another gauze packing reinserted. The patient groaned when the pack was reinserted, but after regaining complete consciousness he said that he had felt no ANESTHESIA. 55 pain during the dressing. Three subsequent: dressings were done on alternate days with no nausea or other after effects nor alteration of pulse or respiration. The patient complained of the taste of the mixture, but said it was far to be preferred to the extreme pain of the dressings. _ Case 8: A soldier, aged 23, with gunshot wound of the left leg, a compound comminuted frackite of the tibia and fibula, a through- and-through infected wound, was given the same mixture. He fell asleep after 15 minutes and slept for 30 minutes during which the dressings were done. The Thomas splint was repadded, the packing was removed and reinserted, ‘and ether’ irrigation was done. Two dressings were done without bad after effects. I found that Major Marshall, anesthetist at Guy’s Hospital, who for three years has been at No. 17 C. C. S., has somewhat modified the Gwathmey method and is most enthusiastie over the results obtained. The formula used by him is: Ether fis z i woe __.-ounces-_ 14 Chloroform____- Se aa _..-minims.._ xx Liq. paraffin, q. s. adi. cali, alae __-__-_ounces__ 4 This is administered 20 minutes before the operation and the patient is not allowed to smell the mixture, in order to avoid nausea. He lies back with a towel over his face, to induce a sort of rebreath- ing. The analgesic is effective for 40 to 50 minutes. It may be rein- forced by light inhalation. Major Marshall has used this method in more than 50 cases with excellent results and points out its usefulness in mild cases in saving the time of an anesthetist. He used no hypodermic with this method. He declares it to be the only type of anesthesia that may safely be used after a meal, and that the patient may eat as soon as he recovers consciousness. I found this oral anesthesia being used in a number of centers which I visited, such as the Duchess of Sutherland Hospital, near St. Omer. Chapple, Schlesinger, and Morgan have used it with success. In fact, wherever ’ found it had been employed they spoke favorably of its use. Spinal anesthesia.—For operations on the lower extremities, spinal anesthesia with a 4 per cent novocain solution is favored by a num- ber of surgeons. Chutro, E. V. Morrow, and others with wide expe- rience advocate this method for painful dressings and wound closures below the waistline. At Buffon Hospital, I saw aie employ it with excellent results in a number of cases. . Marshall has pointed out that in spinal anesthesia ne is a dis- tinct fall in blood pressure. Crile has confirmed this after experi- 56 JOINT LESIONS. ments on animals in his laboratory. He sums up the situation as follows: Spinal anesthesia is, therefore, of value in all rush ald provided that the consequent great fall in blood pressure may be prevented and the psychic factor may be eliminated. He adds that the psychic factor (i. e., the effect upon the patient of knowing what is taking place) may be largely overcome by a pre- liminary dose of morphia or by. nitrous oxide analgesia or a light ether anesthesia. Personal observation in over a thousand cases of spinal analgesia leads me to confirm the fall in blood pressure. So far as the psychic factor is concerned frequently no preliminary hypodermic is needed for there is often a sufficient dulling of me: -mental perceptions to largely eliminate this factor. Rectal anesthesia.—In certain base ‘oan where it is possible to prepare the patient properly beforehand, rectal anesthesia is being employed. It should not be used where there is respiratory difficulty, but where there are to be long operations with plastic work on the head or face it is giving satisfaction. At Sidcup, England, it has been successfully used in over 300 cases. JOINT LESIONS. C. Willems, in charge of the Belgian Military Hospital at Hoog- stade and part of the Military Hospital at Bourbourg, has done some remarkable work in the treatment of joint lesions, and the subject seems to be of ‘sufficient importance to warrant reporting his tech- nique in full. His book is to be brought out at the end of the war, but in view of the frequency of such lesions in war surgery, and of the marked improvement in clinical results frequently following treatment by his method, it seems desirable that this knowledge should be within the reach of.all before that time. His claims were so extraordinary as to arouse a natural skepticism, but after a number of his truly remarkable cases were shown at a surgical meeting in Paris, I felt that a closer study of his methods would be well worth while. Accordingly, I visited the hospitals at Hoogstade and Bourbourg and found that, far from overstating the facts, he would have been warranted in making. even greater claims. The following gives in some detail the treatment of joint lesions by Dr. Willems in his hospitals at Bourbourg and at Hoogstade. In dealing with joint lesions of all kinds, immobilization has been the method of treatment invariably followed.’ It has, however, given such poor functional results that, even before the war began, tenta- tive efforts were made to devise some treatment which would be more successful in preserving the function of the joint. Willems was one A. DeG. Fracture with loss of substance of the external condyle of the femur. Radiographs on entrance. A. De G. Fracture of thigh. Active movements on fifth day. 56-1 . , (a) (b) A. De G. Condition three months after the injury: (a) Arthrotomized knee sup- porting the weight of the body; (b) flexion of the arthrotomized knee. A. De G. Radiograph after cure. 56-2 JOINT LESIONS. 57. of the first to abandon this principle of immobilization, and his work bids fair to revolutionize all of the old ideas on the subject. Since the war began he has had the opportunity of studying a large num- ber of cases and perfecting his method of treatment, which is based on the principle of immediate active mobilization of the joint. He points out that in order to obtain the best results certain general rules must be observed. The motions must be carried out by the patient himself; they must involve those muscles ordinarily used in moving the joint; they must be begun the moment that the patient comes out of the anesthetic; they must be carried out to the point of their maximum ee and they must be as nearly as possible continuous. They should not be supplanted by or combined with passive motion. These movements cause practically no pain unless they produce displacement of a large fragment of bone, in which case such move- ments are contraindicated. This method calls for the constant supervision of a trained at- tendant, and its success depends to a large extent on the courage and good will of the-patient, as well as on his power of coordination. The details of the treatment vary considerably according to the nature, extent, and location of the injury. Joint lesions without injury to the bone.—A simple traumatic hemarthrosis or hydrarthrosis is treated by aspiration and immediate active motion, the patient being instructed to walk if the knee is involved or to flex and extend the forearm if the elbow is involved. Wounds by projectiles call for a resection of the edges of the wound, a uni- or bilateral arthrotomy (always using a vertical in- cision), removal of the projectile and any other foreign bodies, cleansing of the wound with ether, closure without drainage, and in-- stitution of active motion as above described. Joint wounds with injury to the bone—The treatment in these cases varies according to the importance of the fracture and the degree of displacement. When the larger part of the articular surface is intact, and when there is no detached or easily detachable fragment of bone. the treat- ment is exactly as in the preceding cases, plus the removal of any splinters of bone. The cases in this class which give the poorest results are those in which there is more or less extensive injury to the articular cartilages. Another class of cases includes those in which an important frag- ment of bone is detached or easily detachable, thus changing the articular surface and affecting the statics of the ‘oint. If the wound is in one of the arm joints, especially the elbow, the case can be treated as if no fracture existed. The constant motion’ of the joint 93696—19—5 58 JOINT LESIONS. prevents the formation of any intraarticular exostosis and the functional result is good. If the wound is in the knee, certain pre- cautions must be taken. Active flexion and extension must be begun immediately, but the patient can not begin to walk until the bones have knit sufficiently so that there can be no danger of displacement. This requires about three weeks, after which the treatment is as usual. A third class of joint wounds includes those with considerable injury to the bony tissue. This may be subdivided into the follow- ing groups of cases: Those involving an extensive loss of substance of one of both epiphyses; those involving the fragmentation of one or of both epiphyses. In the first group, part of one side of the epiphysis has been destroyed, the corresponding part of the other epiphysis has lost its point of contact and the statics of the joint have been disorganized. In the elbow this is not of much importance since this joint does: not have to support much pressure. The patient will make active flexion and extension as quickly, completely, and easily as with a lesser injury. There will be some lateral deformity and at most some lateral mobility which tends to improve or disappear, but the func- tional result is good. When the knee is affected, the usual treatment should be followed while the patient is in bed. When he starts to walk he is at first unable to bear his weight on the affected knee and should be given a jointed Thomas splint. After several days of walking with this apparatus the patient will be able to walk, using only a cane for. support. A certain lateral mobility will persist, tending sometimes to improve or disappear, though in certain cases the patient will have to wear a jointed leather support for the knee before he can walk without a cane. The improvement or disappearance of the lateral mobility is brought about partly by a contraction of the ~ muscles on the opposite side to the lesion and probably partly also: by the contraction of the ligamentous capsule on the healthy side. If the destruction of tissue has been too great, resection will have to be done, but Willems states that if not more than one whole con- dyle or half of the articular surface of the tibia have disappeared conservative treatment should still be tried, resecting the joint later; if the result is not satisfactory. When there is extensive loss of substance of both epiphyses, con- servative treatment should be tried if, in the knee, the crucial liga- ments are still intact and if more than half of the articular surface is preserved. Resection can be resorted to later if necessary. Pa- tients with wounds of this sort can begin to walk as soon as the wound is cicatrized or well granulated, using at first the apparatus as above described. SER J. M. Open fracture of the fibula with infection; purulent arthritis of the tibio-tarsal joint: Arthrotomy. 58-1 E8-2 .M, After two months, JOINT LESIONS. 59 When there is extensive fragmentation of one or more epiphyses, the treatment must be somewhat modified, inasmuch as the fracture is accompanied by marked displacement. In this class of cases, it is convenient to consider separately injury to the knee and to the elbow, and injuries involving one and both of the epiphyses. Wounds of the knee joint involving only one epiphysis call for a careful removal of all fragments which mani- festly can not be saved, and the application of an extension apparatus fastened by screws above the malleoli. This apparatus, with screws, chains, and foot tractor, is made by Collins in Paris. Active flexion and extension should be begun immediately. This is at first difficult and limited in its action, but may be facilitated by 1 momentary re- laxation of the extension. The length of treatment necessary and the functional result will depend upon the possible infection of the wound and upon the extent of the injury. If one epiphysis is en- tirely gone, there will of course be shortening and almost complete loss of function. If, however, the larger part of the articular surface on one side is intact, the extension will bring the fragments into place and keep them there and the functional result will usually be good. Wounds involving the tibia are much more apt to become infected than those involving the femur. When both epiphyses’ have been shattered into numerous frag- ments, conservation can still be tried if a sufficient number of them remain adherent and, fall into position, after the extension apparatus has been applied. If the treatment succeeds, the joint will be anky- losed, but not shortened. If callus does not form properly, or if it is manifest in the first place that conservative treatment will not succeed, resection or, if necessary, amputation may be performed. If, on the other hand, the damage is less extensive and if after exten- sion part of the articular surfaces of the two epiphyses on one side can be preserved, the fracture may consolidate, and there may even be some mobility of the joint. Of course if the popliteal vessels are injured, amputation will have to be resorted to immediately. When the elbow is involved, conservative treatment should be tried so long as any part of the articular surface of the two epiphyses or even of one epiphysis alone can be preserved. After cleansing the wound in the usual manner, the splinters of bone should be removed, the wound closed if possible and active flexion and extension imme- diately begun. Remarkable results can often be obtained with a minimum amount of articular surface. It is, however, in the treatment of purulent arthritis that the most surprising results can be obtained by immediate active mobilization. It is exceedingly difficult to secure the proper drainage in these cases by arthrotomy, and resection has been, ordinarily, the opera- tion of choice. Willems’ method has the immense advantage of pre- 60 JOINT LESIONS. serving in almost all cases the function of the joint, as well as of simplifying the treatment. He advises a uni- or bilateral arthrotomy followed by immediate active motion of the joint, even instructing the patient to walk after the temperature has fallen below 100 F. and while the joint still has a large opening. So far from being painful, the motions relieve the pain by emptying out the secretions and re- lieving the distention of the joint. Pus is expelled with each con- traction of the muscles, and if the movements are repeated often enough and vigorously enough, the secretions are disposed of as rapidly as they are formed and complete drainage is assured. This treatment should not be supplemented by irrigation, which is, to say the least, useless. As soon as the treatment is begun, the general condition of the patient improves very rapidly, and the temperature loses its septic, character, falling to at least 100 F., although it may not reach normal for some weeks. ‘Locally the suppuration follows the course of an ordinary abscess, though somewhat prolonged. The swelling around the joint di- minishes, but does not quite disappear until the wound has healed. Periarticular abscesses are practically unknown. The secretion is abundant at first, but gradually decreases and finally disappears completely. The motions of flexion and extension are easily made at first, but as the secretion begins to dry up there is a slight tendency to stiffen- ing of the joint. To avoid this danger it is wise to close the arthrot- omy wounds partially, as soon as the secretion has become consid- erably less. It will usually be found that the wound has become canalized along a certain path where the pus is discharged, and this is the only sinus which it is necessary to keep open. Other things being equal, the drainage will be better in those joints in which the movements are more extensive. Thus the elbow and the knee respond best to this treatment, whereas the wrist and the ankle, in which the movements are more limited and the secretion consequently less easily expelled, will respond less quickly. _ The function of the joint will almost invariably be preserved to a large extent, if not completely, and it is not unusual to see a perfect result, especially in the elbow. There is, moreover, practically no atrophy of the muscles. The success of the method seems ‘to be due to the complete drain- age which limits the infection to the synovial membrane and pre- vents it from spreading to the cartilage or bone. At the hospitals at Bourbourg and at Hoogstade I saw many elbow, ankle, and knee cases, fresh and old. Dr. Willems explained his work, which began long before the war, when he felt that sur- geons were doing wrong in not moving joints early enough. This A. Van H. Arthrotomy for projectile in the right knee: (a) Active movements on the fourth day: (b) active movements on the eighth day. ‘| s : SM) (a) (b) . Van H. (a) Arthrotomized knee supporting the weight of the e body; (b) fexion of the arthrotomized knee three weeks after the injury. 60 J. Van H. Extension and flexion 14 days after the wound, in spite of gas gangrene, J. Van H, Extension 18 days after the wound, 60-1 J. Van H. Active movements two months after the wound before skin grafting. 60-2 (a) (b) J. Van H. (a)7After skin grafting; (b) extension and flexion five months after the wound, 60-3 (c) (a) J. Van H. Splintered fracture of the external condyle of the femur in the right knee. Radio- graph after cure. (b) V.R. Wound of the right elbow; fragmentation of the olecranon process and splintered fracture of the ulnar epiphysis. Radiograph on entrance. (c) V. R. Radio- graph after removal of splinters. 60-4 V.R. Radiograph after removal of splinters. 60-5 V.R. After three days, V.R, After seven days. V.R. After ten days. V.R. After four months. 60-6 J. M. Two splinters of shell in the right knee. J. M. Active flexion and extension on the eighth day. 60-7 (a) (b) J. M. Condition three months after the injury: (a) Arthrotomized knee supporting the weight of the body; (b) flexion of the arthrotomized knee. 60-8 JOINT LESIONS. 61 was in nonseptic cases. Since the war he has enlarged the scope of his work. He willingly answered all questions and furnished me with pictures of some of the cases I saw. These are annexed hereto. One case which I saw was a purulent synovitis of the knee, strepto- coccus in type, which had been’ under treatment for three months. Pus squeezed out from the joint as the leg was fully flexed and ex- tended, but the joint surfaces were of a clean red color, and there was no pain on motion, or when the patella was grasped and pushed or pulled from side to side. Another streptococcus knee case, seen on the fourth day, was able to flex and extend his knee with a fair amount of freedom. A compound fracture of the ankle, operated on the previous day, had been opened, cleansed, and sutured up tight, and the patient was already beginning to move it without pain. A fractured patella had been sutured with silk-worm gut, which was left in, and the patient, six days later, was walking easily. Another patient had had a compound fracture of the elbow, in- volving the external condyle and epicondyle. The bone had been re- moved, the edges of the wound cut away, the wound cleansed with ether and sutured up without drainage. Seven months later there was perfect union with no loss of function. . Willems gives the following statistics with regard to 100 consecu- tive knee cases. Eighteen of these were accompanied by.a purulent synovitis of a virulent type, chiefly streptococcus, but in the 100 cases there were no deaths and no amputations. There was one re- section in a case in which the crucial ligaments were gone and the popliteal artery was thrombosed, and there were two stiff joints, one of which it was hardly fair to count, since the patient had. failed to follow directions. Dr. Willems was thoroughly imbued with the belief that many would be saved joint and limb by the treatment which he recom- mended, and his great desire was to save the soldiers and not to prove his theory to be correct. Both Major Lockwood, D. S. O., B. E. F., chief surgeon C. C. S. No. 36, who accompanied me, and I had been skeptical when we went to see the cases, but came away greatly impressed by what we had seen. The results certainly were wonderful and bore out Dr. Wil- lems’s claims. : There is unquestionably much to be learned from this man. The treatment of joint cases by his method without doubt gives better functional results and a larger percentage of cures, and it seems evident that when this method. becomes more generally known it will modify, to some extent at least, if it does not supplant, the practice of most surgeons to-day. 62 FRACTUBES. FRACTURES. In 1911 the International Congress of Surgeons selected the sub- ject of simple fractures as the main topic for discussion’ at the session held in Brussels. Leaders from all over the world gathered for a three days’ conference and freely exchanged their views in an at- tempt to-arrive at a conclusion as to the best treatment for this class of injuries. In a large hall near by were exhibits, such as charts, pictures, drawings, slides, apparatus, models and graphic statistical records of fracture cases. To those of us who were onlookers, it was obvious that there were three groups with conflicting opinions. There were those who em- phasized the value of open operative treatment and reinforced their arguments by showing the poor results obtained from the employ- ment of other methods. Again, there were the earnest advocates of the practically exclusive use of apparatus, who sought to demon- strate that operative results did not compare favorably with those obtained when the essentials of mechanical treatment were observed. Then there was the third group which pointed out the unfortunate consequences likely to follow if either of the first two methods were adopted. They maintained that in a large number of cases the best results could be obtained by insuring immobility and correct align- ment through the use of sand bags or the like, while at the same time minimizing circulatery interference by reason of pressure. They used massage at once and passive motion early. In all three, the adoveates admitted that there were exceptions but maintained that the rule was as they severally claimed. Here were the wisest honestly differing. Apparently at the close of the conference there were still the three opinions, although each group had learned much of the viewpoint of the others. Since 1911, there has been a gradual coming closer together, but at the beginning of the war there was still a wide divergence of opinion as to the best treatment of many fractures, simple as well as compound. After four years of war experience, while there are radically differing methods in vogue, there are nevertheless, certain essentials as to which there is close agreement. Early in 1915 the death rate in some classes of compound fractures was appalling, but owing to improved methods this has been greatly reduced and a contrast between the mortality and morbidity then and now is most gratifying. Immediate immobilization, the use of a Thomas splint or some modification of it, careful splinting so as to allow of no grating of bone ends, the removal of foreign bodies introduced with the projectile, the types of cases which may be safely evacuated and those which should be left behind and the importance of not: dis- KETTLE OR IRON PLATE. RECHAUFFMENT. ~-at FIG ut. We eee BLANKETS & STRETCHER FIG \ PATIENT HEATING UP Wh Bey HEATED READY FOR PATIENT PATIENT READY FOR TRANSPORT [ 7 i = FIG Jit. on Wate: proof Sheet D » > SSS ee i 1 1 ESSE 1 | | FIG |! 7 Warming (Réchautiment) if Extension Jit. Cleve pitch over Buot 1¥. Splint Ficatie FRONT LINE APPLICATION OF THOMAS SPLINT ‘ FIRST ARMY (R.A.M C) SCHOOL OF INSTRUCTION 1917, e Front line application of Thomas splint. First Army (R. A. M. C.) School of Instruction. 62 FRACTURES. 63 turbing the injured parts any more than is imperative are all sub- jects upon which there is substantial agreement. Other questions, such as the extent and character of operative interference, whether antiseptics should be used at all, and if employed, which one is best, and the kind of splint which should be used after the case leaves the casualty clearing station are as yet matters of varying opinions. The field of special hospitals is developing rapidly. The French have established certain hospitals for the ‘care of fractures, each with a specially trained staff in charge. Other institutions have set apart entire wards for this work, resulting in uniformity of treat- ment and increased efficiency. The British in their orthopedic cen- ters have gone a step farther and are sending to the Eighth General Hospital at Wimereux, and the Red Cross Hospital at Netley, as many as possible of their thigh fractures. Thus there is being created a specialty within an already specialized field. Colonel J..A. Blake has been particularly interested in the treat- ment of fractures and formerly at the American ambulance, Neuilly, and now at the American Red Cross Hospital No. 2, is devoting him- self largely to their care. Recently a start was made on a hospital to be used exclusively for fractures near Chalons-sur-Marne, but the German drive interfered with Colonel Blake’s plans. Doubtless this . unit, with those of Colonel Goldthwaite and Major:John B. Walker, all of the Medical Corps, United States Army, and others, will do for us what Jones, Sinclair, Souttar, Thevenot, Patel, Leriche, Gosset, Depage, Willems and their confréres have done and are doing for our allies. Colonel Sir Robert Jones, C. B., director of the orthopedic centers of Great Britain, will shortly jase a volume on his experiences in dealing with this line of cases. Colonel Blake has in press a book on fractures. Prof. R. Leriche of Lyons, lately at Bouleuse in charge of fracture cases, has already brought out this year the second volume of his work on this subject. Prof. Willems and Major Sinclair state that they will not have their books ready until after the war. All these authorities differ materially in theory and practice, but all are doing excellent work and obtaining good results. I refer only thus briefly to those whose books are bringing within our reach at the present time their views and opinions. The work of Sinclair and Willems, however, is extremely important, and as now, when we most need to know what they are doing, it can only be learned through a personal ‘visit or through some one who has had an opportunity to see it at first hand, I have attempted to describe some of the outstanding features. Essentials of Sinclait’s method—I visited the Eighth General Hospital a number of times and went through the fracture wards with Major Sinclair and saw many wonderful results of his treat- 64 FRACTURES. ment, especially in cases of compound fracture of the femur, in which he is particularly interested. He said: Immobilization and drainage are the main elements of success in the treat- ment of compound fractures. My method is—Thomas splint, sterile dressings, free drainage. Immobilize as early as possible. I would do this at the ad- vanced dressing stations, putting on a Thomas splint at once. Treat the wound after immobilization. Thus the ends of bone are kept from doing harm and opening up new avenues of infection. Wait and see if there is trouble before overdoing the surgery. Never mind the fragments of shells or bullets unless they do harm. It is the infection that injures—the organisms. I often leave in bullets that are doing no harm—leave them unless they require removal. Preserve pieces of bone that are in any way attached. In the beginning of the war we removed all the pieces and some do this still. Don’t do it. What is the use of taking away a natural graft and months later transplanting bone frofn the tibia? We never see shortening unless part of the femur has been removed, in fact, the patients go out with the leg a little longer than normal, Splint early and do not disturb any more than necessary. I even do ‘small operations in the ward, such as inserting calipers or traction screws, in order not to move the patient about. Drain with rubber tubes, putting as little fluid as possible into the wound, if any is used at all. I employ a little peroxide full strength to clean the wound. We do not use Carrel-Dakin. .The antiseptic is injurious to the tissues and washes away the blood serum con- taining the antibodies with which nature fights off disease. I use alcohol and then 3 per cent picric acid upon the skin before incising. In compound frac- tures of the femur incise at least 4 inches in length where there is good de- pendent drainage, fhen use dry dressing. Introducing the finger into the wound and feeling about, tearing the tissue or curreting is bad. Drainage by repeated clean cuts is the best. Any plaster which contains rubber is ‘Likely to irritate and blister the skin. I have prepared a glue which acts well and holds for some weeks without difficulty (see formula). Unless drainage is necessary most of the cases of fracture of the thigh do not require any anesthetic for reduction, but proper traction for 24 to 48 hours accomplishes it. Sixty per cent will be held down by the use of glue; 40 per cent need other holding points. In order of preference, the points of direct bone traction are: / 1. Three fingers below the tubercle on either side of the tibia; two screws should be inserted part way through the bone but be sure they do not go all the way through. Then tape is fastened on metal loop. 2. Calipers to malleoli, so fixed as not to go more than one-quarter inch into the bone on either side of foot. 8. Condyles of the femur, with large calipers. 4. Calipers to os calcis. There will be no pain or discomfort of any moment, and none at all after 24 to 48 hours. Do not move the patient from where he is, and if properly treated he will be able to walk in three or four months. For fractures of the upper third of the thigh, while in a position of marked abduction, the patient is supported in a swing bed on a sheet made of a network.of strings. In all other cases, and for the upper extremity, I use a Thomas splint as slightly modified by me. Observe temperature and pulse and examine local condition with X-rays. It takes the greatest care of details to succeed with this work, but if the method is followed strictly one does not see those terrible sinuses persisting and having to be re- FRACTURES. 65 peatedly curetted for dead bone. For anesthetic I use chloroform 1 part, ether 2 parts. There should be special hospitals for the care of fractures, and the surgeon who applies the permanent dressing should see it through to cure. There is not the- interest or uniformity of treatment if the case changes hands. America had better leave her thigh fractures over here until they can walk. For the purpose of collecting any discharge from a dependent wound, a small sterilized pus basin is placed under the outlet of the tube which is inserted for drainage. Major Sinclair emphasizes the importance of noting the character of the discharge, as it affords clinical data of value. The tube itself has perforations within the wound, but is not spirally cut and has nothing over the outlet. He considers this importaht, as there is no danger of damming the drain- age. (This is a practical point and should be considered in other conditions requiring drainage.) He says: “ Bone is formed from bone, not from periosteum alone.” In this he differs from Chutro and agrees with Sir William Macewen of Glasgow. The latter has grown an entire shaft of a humerus by chipping off pieces of solid bone (in operating for bowlegs and knock-knees) and placing them between the two ends of the humerus, the whole shaft growing solid from these pieces. This took a number of years. SINCLAIR’S FORMULA FOR ADHESIVE GLUE. TEST FOR GLUE. Place 4 ounces of glue in 4 pounds of cold water and leave in a cool place fer 12 hours. If dissolved, it is bad. If coherent and gelatinous, weighing 8 ounces, it is good. If coherent and gelatinous, weighing 16 ounces, it is very good. If coherent and gelatinous, weighing 20 ounces, it is excellent. The following is the formula: Very good glue. oi 220-2 eee we esses seeeseceeeseseeses 50 parts WateReoce scene sot een leek ss soso e ee eh ee ea 50 parts Gly C6LING@L. asso ose Sssee een aceetaesepee eee esiesel Sosa cess snd 4 or 6 parts Menthol 23 ane eh ee ee Se eo Se ee eso 1 part Soak for 12 hours and then melt on.a water bath. Neutralize to litmus with sodium hydrate, as commercial glue at times contains free hydrochloric acid. Add 4 parts in summer and 5 parts in winter of glycerine and 1 part of menthol. Frequent heating evaporates the water, which should be added from time to time. When reheated many times, adhesive power is lost. Technique: 1. The skin is not shaved. 2. Wash the skin with soap and hot water, which contains about 4 drams of washing soda to the pint, to convert the oil of the skin into soap, as glue will not adhere to a greasy surface. 66 FRACTURES. 3. Dry the skin. 4. Apply the warm glue evenly, brushing all the hairs of the limb in an upward direction. 5. Keep a tension on the gauze all the time, bring it quickly but carefully into contact with the limb (inner and outer surface), and apply neatly a loose- woven bandage, starting a hand’s breadth above the malleoli up to the knee joint. 6. When dry apply traction. (The adhesive can be made waterproof with a 2 per cent solution of potassium bichromate applied in the dark and then ‘exposed to the light, or by means of formalin.) _ %. The extension must always be very carefully applied, whether with Maw’s elastic cotton net or with gauze. 8. The extension must be changed at once if the patient complains of a tick- ling or burning sensation under it, but it generally requires changing about the tenth, twentieth, and fortieth days. WILLEMS’ SCREW EXTENSION APPARATUS. This apparatus for continuous extension of fractures of the femur and leg bones consists essentially of 2 screws,‘a bolt with 2 short at- tached chains, and a stirrup at the 2 ends of which the chains are fastened. For femoral fractures, the screws are introduced into the uppermost portion of the condyles close to the diaphysis, and are inserted to a depth of 2 to 8 centimeters. For fractures of the leg bones, the screws are placed above the malleoli, at a depth of about 2 centimeters. The bolt is approached close to the skin so as to render the traction juxta-cutaneous. Counter-extension is made by suitable adjustment of the bed. ei The principal advantages of this apparatus are that: 1. Traction is exerted directly on the lower fragment, a condition not met by any other method of continuous extension. The result is great accuracy and efficiency of the traction. No part of the force being lost, the object is accomplished by a relatively weak traction. 2. The disad- vantages. of indirect traction through one or more articulations are obviated by this method exclusively. 3. The apparatus leaves free the entire surface of the limb, thereby facilitating the care of the wound. 4. Mobilization of all joints is possible during the entire treatment. 5. The apparatus not only prevents overriding of the fragments, but permits the correction of angular deviations by chang- ing the axial into lateral traction. The screws are very readily tolerated provided they are firmly fixed in the bone, above the epiphyses, where they remain indefinitely in place, causing no tenderness. The insertion of the screws never breaks the bone, and radiography has never revealed the smallest fissure, even in the case of the fibula. Screw extension is easily combined with suspension by means of the Thomas splint. For the evacuation of the wounded, to which Fig. 1.—Extension apparatus; two screws with two short chains terminating in a stirrup which bears a hook for the traction cord. Fig. 3.—Apparatus in place for fracture of the thigh, combined with suspension. Fig. 4.—Apparatus in place for femoral fracture. © Spring ; extension for evacuation. Many hospitals are doing excellent work in caring for fracture cases, and the accompanying pictures show a fracture ward at the Val-de-Grace Hospital, with its many varieties of appa- ratus needed, and also a fracture splint in position as used at that institution, 66--2 FRACTURES. 67 the apparatus is very well adapted, it suffices to substitute for the ex- tension with weights an extension on a spring interpolated between the stirrup of the Willems apparatus and the extremity of the Thomas splint. (Presse méd. No. 69, 1917.) A splint which is receiving much favorable attention and being widely used is one devised by Leclercq and Varigard, and about to be described. APPARATUS OF LECLERCQ AND VARIGARD. 4 (For reduction and maintenance of fractures of the humerus.) _ | This continuous extension apparatus has been adopted by the sanitary service of the French Army, and is in use in the English Army. It is intended to reduce and retain complicated fractures of the arm (humerus), while permitting the application of dressings and other interventions necessary for the healing of the fracture. Made entirely of metal, nickel-plated copper, in order to avoid oxi- dation, this apparatus has been devised and manufactured in con- formity with modern methods. It serves for the right as well as the left arm (symmetrical and interchangeable axillary splint) and is easily and quickly applied (in about 10 minutes) with only two flan- nel bandages. With the apparatus once adjusted the patient has no further pain or inconvenience; he is not kept immovable in bed, but may go and come, or be evacuated in the sitting position. Suppura- tion is reduced to a minimum, and reduction is as complete as pos- sible. Dressings are easily applied without displacing the appa- ratus. Bony consolidation takes place rapidly. In grave cases, am- putation may thus be avoided. The apparatus saves time, suffering, limbs, attendance, and money. The adjustment of the apparatus, which serves for either arm, is best understood by a study of the explantory illustrations. Some preliminary precautions should be observed. The hooks for fastening the arch must be on the side of the thorax; when they are on the arm side the position is incorrect. Open the screw, turn back arch A, replace the screw after having pressed the bolt into the hole of arch P, as shown in the illustration. Before applying the apparatus the wound must be dressed (not too thickly). Lightly stuff the axillary arch with cotton wadding, held in place by a strip of gauze or oiled silk. Pad the forearm with a good thickness of cotton wadding held in place by a strip of gauze. Make three small cushions, to be placed between the extremities of the arch and the shoulder, as well as over the shoulder itself. These cushions are best made with cotton held in a napkin or a piece of cot- ton wadding may be wrapped in a strip of gauze closed at the end with a few stitches. Place the apparatus on the healthy side to oY 68 FRACTURES. ascertain the proper length. Lengthen or shorten, by opening the screw and changing the hold. There are four such holes on the splint, No. 2 from below fitting a medium-sized arm. The apparatus is now applied by slipping the arch under the screw and then ad- justing the forearm plate, the patient being instructed to hold his elbow with the healthy hand. Note that the attachment of the ap- paratus is thoraco-suprascapular. The arm should be placed slightly backward, so that the thoracic hooks are very straight. Hold in place with very long (6 meters) flannel or cotton bandages about 10 centimeters in width. The fore-arm plate must not lie too tightly in the bend of the el- bow. In order to change the dressings, the fore-arm plate can be loosened, slipped forward, and then replaced. The shoulder can be mobilized after having opened the screw, then proceeding to abduc- tion or to adduction. In forcibly holding the lower portion of the humerus so as to immobilize it, the elbow joint may be made to work, by means of a special contrivance. This should be done every day when the wound begins to improve. The apparatus having been adjusted, the tension of the spring is regulated by turning the tension buttons near the fore-arm plate. The spring gives 2 kilos of extension when its length taken vertically is 4 centimeters. This is the most that should be used. The rule is to tighten the spring gradually and to verify the proper position of the bone fragments by radiography. There is always a tendency to overtighten the spring; great care must be exercised, for the frag- ments would separate and consolidation would not be obtained. Keep in mind that the extension is continuous. Some edema of the elbow in the first days is not serious, and simply requires lessening the extension. Other splints of various types are being used, such as the Paterson splint for fractures of the humerus, and the American Red Cross splint, which are illustrated here. The French Army has developed an admirable system for the care of fractures and joint injuries which insures the patient remaining under the control of the same staff of surgeons from the time he is injured until he is discharged from further treatment. This results in uniformity of treatment, a definite feeling of responsibility on the part of the staff, and a higher measure of success because of these two factors. This system, as it is now in operation behind four of the French armies in the field, is arranged as follows: The patients are received in hospital No. 1 from Chee to six hours after injury. They are X-rayed and operated upon and the proper splint is applied. If possible they are not moved until the union of broken bones has been established. There’ is some criticism of this FIG. 1 VUR DE WAPPARELL A are axillure riculanan d/assemblage articulee 3 arrima ¢ C FIG. 2 68-1 sin position. Front view, Device for immobilization of fracture of arm applied. Paterson splint. 68-4 Paterson splint. 68-5 68-6 Adjustable abduction arm splint made in the American Red Cross splint shop. 68—7 New adjustable abduction splint perfected for the U. S. Army by the American Red Cross splint shop. | 2—Arm extension splint in place. 68-8 Photograph made from pencil sketch by Maj. H.S, Souttar. (See special section, British Red Cross Hospital, Netley.) 68-9 TREPHINED CASES. 69 arrangement on the score that it is harmful for a patient to be re- tained for a long period within the battle area with its noise of con- flict and constant danger of the necessity for a rapid evacuation. It may be that in the new French Army plan this will be changed and such hospitals placed much farther to the rear. After leaving hos- pital No. 1, the patients are transferred to hospital No. 2 from 30 to 50 kilometers to the rear. Here any necessary repair work is done, bone infections are treated, and the cases remain until convalescent, when they are sent to hospital No. 3. This class of hospitals is lo- cated well to the rear and in such centers of physiotherapy as have been established; where there is provision: for. massage, mechano- therapy, fitting of artificial limbs and the like. A board composed of Colonel William L. Keller, Medical Corps, Colonel Joseph A. Blake, Medical Corps, and Captain Nathaniel Allison, Medical Corps, visited four French Army areas where this system was in vogue and made the following report to the chief surgeon of the American Expeditionary Force as to their conclu- sions: 1. The board has carefully observed the character and efficiency of the splints and appliances used at these various centers for the treatment otf fractures and as a result is gratified to state that in its opinion the appliances in splints recommended for use in the American Army under your direc- tion are sufficient and practical to meet all the conditions even better than those in use by the French Army. 2. The board feels that an improvement can be made in this system by having the simple splints which supply the principle of traction applied when the man receives his first surgical dressing. 3. Infection is to be avoided if possible. To this end the French system ‘1s admirable. The board feels that fractures and wounds of the soft parts and injuries to joints can he primarily closed in a large percentage of cases if they reach an operating hospital in the first few hours after receiving their wounds. 4, Hospitals for the treatment of fractures and injuries to joints should be special services and should be equipped for X-ray work and operation and for after care. The most capable surgeons should direct the work at these stations. 5. The board feels that so far as is possible the above outlined system should be followed in the American service. It has taken the French three years to evolve this system. It is still not in use by the British. We feel strongly that our own results will be greatly improved by following the principles of this system. 6. The staff arrangement for fracture services should be as follows: The chief surgeon of the group should direct the entire service from hospital No. 1, that is the hospital near the front. The surgeons at Nos. 2 and 3 hospitals should work in complete cooperation with him. TREPHINED CASES. A very difficult class of patients to deal with is composed of those who have been trephined. At the schools for reeducation, the farms for the mutilated, and the clearing depots, such as at 28 Quai Debilly, Paris, the frank statement is made that these men are usually mis- 70 TREPHINED CASES, fits. They do not get along well with other patients, and while they often look entirely well they never seem to feel right. They are obsessed with the idea that something is going to press on their “soft spot,” and their actions are frequently peculiar. Headaches and a long train of nervous symptoms are complained of. — Dr. Lines, at the clearing house of the Colonie des Etrangers, in speaking of two such cases who had been returned from other insti- tutions to Paris, “because they could not get along with the others,” said: No reeducation, even on a farm, could do much for trephined cases. It is almost useless to try to help these men. . : The same opinion was expressed elsewhere, and I early realized that here was one of the great problems of the war wounded. Medi- cal treatment gave very indifferent results. I was therefore anxious to learn whether anything of real value had been developed in sur- gery for the relief of these unfortunates. I found that Morestin, Gosset, Chutro, and a few other surgeons had done considerable work along the line of filling up the gaps left in the skull by introducing between the skin and the dura a plate of some kind. By this means protection is secured from pressure and relief from direct adhesion between the dura and the subcutaneous tissue—often the scar. Upon learning that many of these operations had been performed at the Buffon Hospital, and that Prof. Babinski, not only the lead- ing neurologist in France, but one of the greatest in the world, had followed the results, ,I went to him for his views. He very courte- ously and freely discussed the treatment of this class of cases, show- ing histories and patients. He said: Trephined cases usually are a most unfortunate lot. I have nothing special to offer them in the line of treatment. I either wait to see how time will affect them or have an operation, Some get a little better after awhile if left alone, Gosset’s and Chutro’s results are excellent from the surgical standpoint. The cranioplastie operation should be tried, but I am not willing to give a final ver- dict from the neurological point of view. Years must pass before that can be given. I would advise operation in all cases where the symptoms are persistent and marked, and the scalp is adherent to the deeper structures. Whether cartilage or bone should be used is a matter for the surgeons to decide. Some say that bone is absorbed and others that cartilage is absorbed. , To sum up, the opinion of this great authority is, in trephined cases with persistent symptoms; do a cranioplastic operation, but do not. promise too much. The employment of perforated silver plate coverings for cranial gaps has been found serviceable in the experience of Mitchell (Brit. Jour. Surg., July, 1917). The thin plate (not so thick as an ordinary visiting card) is punched with holes one-eighth of an inch in diam- eter as close together as possible. The orifices, aside from helping TREPHINED CASES. 71 to fix the plate, permit the escape of blood or other fluids thereby guarding against pressure.,on the brain through accumulation be- tween the plate and the dura. The fitted plate is held in position by a series of catgut sutures passing through the periosteum and out through the most convenient perforations. The scalp flap is sutured over it, and a drainage tube inserted at the most dependent angle for 24 hours, so as to avoid the formation of a hematoma. In the experience of ‘the originator of the method, primary union was ob- tained in all of his six cases and the operation was followed by marked relief of symptoms. Cranioplastics by means of osteocutaneous or osteoperiosteal flaps proved highly satisfactory in the experience of Cazin, and Mayet recommends the repair of a loss of cranial substance by turning down an osteoperiosteal flap cut from. the external table of a con- tiguous region of the skull. ; After the performance of a trephining operation, the gap in the skull is probably most advantageously closed by means of cartilage which combines a certain yielding property with sufficient solidity to provide the necessary protection. The relief obtained in cases of painful cicatrices is most gratifying. The cartilage may be ap- plied in a series of autoplastic or homoplastic layers, according to Morestin’s method, or in the form of a sometimes voluminous single ‘segment of cartilage, with its perichondrium, in order to prevent the ultimate formation of adhesions with the brain. The last named plan is followed by Gosset, who reports 15 successful cranioplastic operations with excellent results (Bull. et mém. Soc. de Chir., de Paris, vol. 42, 1916). The repair of the gap left in the skull after trephining, by means of cartilaginous grafts, has the advantage of providing a perma- nent and physiological protective covering of the head. These grafts are accorded preference by Warren Woodroffe, surgeon to the Ulster Volunteer Hospital, because they are safe, simple, autoplastic and autogenous. Cartilage moreover is highly resistant against infec- tion, making this tissue a practically ideal material for reconstructive surgery. The grafts are shaved from the sixth, seventh, or eighth costal cartilage, and may be held in place by a network of catgut attached to the margin of the pericranium, the hole in the skull being filled by an adjustment of overlapping grafts beneath this catgut trellis. Although no bony change follows, the cartilaginous plate affords a satisfactory and reliable closure of the gap in the bony skull. It must be mentioned, however, that phenomena of cerebral com- pression have been reported, following the closure of a cranial gap by a large piece of cartilage (Bull. et mém. Soc. de Chir., de Paris, 12 Dec., 1917). 72 AMPUTATIONS. To return to the Buffon Hospital. At Chutro’s clinic I saw a number of these cranioplastic operations and some post operative results. The patients I examined certainly were in excellent condi- tion and the records were most satisfactory. Chutro’s operation is a modification of Gosset’s, with the use of rib cartilage, and done. under local anesthesia. He has had 62 cases with uniform success and I was most favorably impressed with the method of operating, the technique of the surgeon, and the results in those patients ob- served. Although the details of this work have not been published by Dr. Chutro,; in response to my request he allowed me to send an artist to his clinic and he himself wrote out, in Spanish, a description which is to be made a part of this report. AMPUTATIONS. FOR THE LEG. 5. If one can not do a Syme’s, do an amputation at the junction of the lower with the middle two-thirds. This is an exception to No. 1, which says: ‘“ Con- serve the length of the lever.” Don’t operate in the lower third of the leg if you can help it. The objections to the lower third are as follows: (a) The stump is always cold because of poor circulation. (b) It is always sensitive, 6. The minimum length of the lever in ordinary cases which is utilizable is 2 inches below the knee. 7. Never take out the head of the fibula because you sacrifice the attachment of important flexible muscles. _ 8. The preferred length of the lever of the leg is 4 inches below the knee. With 4 or 5 inches one can secure practically 100 per cent efficiency with an artificial member ; 75 per cent efficiency with 2 to 3 inches. The steel and leather orthopedic leg with laced corset about the stump has been given up practically by the French. They have adopted the American leg and principle. This was done about June, 1917. At the present time they are using approximately 15 per cent of American legs. We know this because they are being manufactured to that extent for them. The French have not yet gotten around to doing it successfully. The steel and leather leg is gone for good. ' The improved American leg is the one gotten up by Hendricks and Martin, of Belgium. They differ somewhat in theory but very little in practice. One can read their articles, which deal more with theoretical than practical differences. Prothesis has been extended since the war far beyond the field of dentistry where it originally started. We may define prothesis as a system of restoring an amputé to his maximum efficiency. FOR THE THIGH. (a) Operation. (0) Treatment. Cushions are bad. Put.the thigh out straight, not flexed. Extension after amputation helps save from contraction, deformity, and ankylosis. Tends te prevent adhesion of the scar to the bone. . (c) Always turn a patient on his face and extend the thigh for a few minutes each day. One such movement daily will do an immense amount of good and saves contraction. s (d) Disarticulation of the knee or other joints, except the shoulder or hip, is bad. (e) In thigh amputations get the maximum length. (f) Disarticulation of the hip ought to be done in two stages, as it means much less mortality. Amputate the thigh and later disarticulate the bone by lateral vertical incision. FOR THE LOWER LEG. (g) Crutches are very bad. They change the statics of the body. Bad habits are formed. They can walk early with provisional apparatus. End bearing pressure does not exist. Bad-looking stumps often are most useful. This doing away with crutches is best, yet we have many crutches. The Gov- ernment has not yet taken hold practically of the provisional apparatus. The crutches are easy to get and supply and it looks well to get the patients up quickly. AMPUTATIONS, 77 WHY DO AWAY WITH CRUTCHES? 1, Deformities are produced by crutches in the way the man carries himself. 2. There is always pressure atrophy when apparatus is used. There is atrophy of disuse which is prevented when we employ provisional apparatus. Thus by the early use of provisional apparatus we save one kind of atrophy, which can be prevented, and we have early the atrophy from the pressure of the ap- paratus and can more quickly adjust the permanent apparatus. Then a stump has, as a rule, an extra accumulation of fat if it hangs, so by early use of apparatus we save this extra increase of fat on the stump, which must later disappear. This takes time. 3. Loss of time. The form of the stump does not take its final shape as quickly if crutches are employed, as when provisional apparatus is used. 4. Bad statics. The statics of an individual are transformed. He gets a new habit of walking which has to be overcome. Provisional apparatus can be used in about 14 days for amputations below the knee and three weeks for the thigh. Don’t use crutches. Instead use provisional apparatus, The patients get out very nearly as quickly. PROVISIONAL APPARATUS, The best is plaster of Paris molded with steel rods at the sides, a bolt in the center for the knee, so as to allow all flexion, and suspenders over the shoul- ders holding up the apparatus which is molded to the extremity. A leather corset is used above on the thigh. Use the end bearing when it exists, but it is not usually necessary. When both legs are off use provisional peg legs but no crutches. Give them a stick to walk with. our VALUE OF PROVISIONAL APPARATUS. 1. Correct statics. 2. Active agent physicotherapy. 8. Hastens atrophy of stump; lessens time of evolution of stump one-half. 4, Saves cost. Provisional apparatus can be had for $7 or $8, whereas if no provisional apparatus is made there will be an additional fitting adjustment to the permanent apparatus costing $20 to $40. The extra period of fitting is most trying on the patient. 5. Finally, there is the mental side of it all. When the member is removed profound depression comes on. The patient sinks down to the level of a professional cripple. He feels himself a human derelict. Provisional apparatus lessens this greatly and combats this tendency as early as possible. At Rouen they get the patients to hop before they have provisional apparatus, so as to encourage them. Begin as early as possible to let them see they are going to do something and be something in the future. 6. Saves by early use much stiffness and maybe ankylosis of near-by joint. Prevent the crutch habit. A Danish surgeon, Dr. Svindt, developed one of the best provisional apparatus, a cardboard peg leg for provisional use with a starched bandage. The funnel end is open. POINTS OF SUPPORT. 1. Bony prominences the points for support in all apparatus. 2. The soft parts of the stump. 8. The end of the stump when utilizable. 18 AMPUTATIONS. Legs and thigh are so far all that we have studied. Musculo-spiral paralysis or crutch paralysis—So many of these cases of crutch paralysis have been seen in France that there has been demanded and produced an ultra-brachial crutch. Still it is bad. Get the amputated leg case up early, but don’t use the crutch. FINAL APPARATUS. This depends largely on what the patient is to do hereafter. 1. The peg leg.—It is simple, any one can use it and it is not expensive. When going to do hard work it is the best. It gives the maximum strength with the smallest cost for repairs. It is well constructed, and the French have , developed it exceedingly well. With a decent socket and a joint-lock at the knee the man really sits in it with comfort. 2. The articulated leg—It looks much better. The splint manufacturers are entirely against the peg leg. An artificial member is to serve always either of two purposes: One is fune- tion and the other appearance. One must weigh up the two. A peg leg may mean added advantage in some cases; in fact, with a peg leg a man may even capitalize his injury. This is a dangerous philosophy, but it is actually a fact, WHAT CAN A MAN DO WITHOUT A LEG? 1. After an amputation below the knee, as indicated above, he can do any- thing as he did it before. There is no problem of reeducation here at all. 2. Above the knee there is need of reeducation. The man may become a shoe- maker, a basket maker, a shopkeeper, or he should certainly be taught a trade which would allow him to sit a good part of the day, fruit culture, etc. There are many outlets for him. The French have turned most of them into shoe- makers and basket makers. Of course, these cases of mutilés of the lower extremities are usually young men and they can easily learn. Most manufac- turers will tell us that they can take a man from any place in which he is working and make him do more work and better work than the trade he has himself selected. A time may come when efficiency engineers will put the man in his most useful place. Captain Miller states that in making legs they have developed a real business which is growing every day. The Red Cross stands ready to furnish limbs or give any aid along the lines indicated herein. It will put its resources at the disposal of both Americans and French. to be of assistance from the time the patient leaves the operating table until his return to his maximum efficiency. He also states that up to date in the war there have been 60 per cent reamputations, necessitating greater loss of limb, which is a dis- tinct economic waste. From the standpoint of fitting splints, the flaps in amputation are bad. The site of the scar is negligible—absolutely of no importance. Flap amputations being bad, circular amputations are first choice. AMPUTATIONS. 79 Statistics of amputation from August 4. 1914, to March 1, 1917. FRANCE, Upper limbs : ‘ 25 per cent. Lower limbs. 75 per cent. : 64 per cent thigh. Of the lower limbs. : =e 34 per cent leg. Disarticulation of hip 4 1 per cent minus. Syme’s and Pirogoff amputations epi ieeeerte pe es, 1 per cent plus. Of considerable interest is the questionnaire sent out to the Eng- lish and Belgian centers of prothesis and to 12 cities in France, in- cluding not only the ones in charge of these centers but also the chief surgeons. The answers represent a large majority of those who replied. ‘ In order that this bureau may render an intelligent report to the United States Army as to the best methods of amputation of the lower limb, will you have the kindness to answer the following questions and return to me in an inclosed envelope. All of these. questions are in regard to amputating stumps of the thigh or leg and do not include disarticulation of the knee or hip or amputations of the ankle such as the Symes or Pirogoff. 1. Do you consider the ability of a stump to bear weight on its end as of any importance? No. 2. When a stump is able to bear weight on its end, do you utilize this ability when fitting an artificial limb? If so, how? No. : 8. With an artificial limb fitted so that the end of the stump bears much of the weight, have you ever remarked improvement in the epishy of the mutilé to walk or work? No. Because they have had no experience with it. 4. Given that end bearing is usually secured in the types of stumps, above described at the expense of length, do you think the surgeon shoud be advised to strive for end bearing when making an amputation? Secure maximum length of lever. Major Edred Corner, of the Fifth London General Hospital, gave me a synopsis of his experience as to amputations, which will be found under the description-of the work at that hospital. (See Fifth London General Hospital.) From the experience of all of these authorities, the following generalizations may be made: 1. Every surgeon who amputates should know the best place for amputation consistent with the obtaining of the best functional re- sults for the use of apparatus. 2. The horror of amputation should be mitigated in thie minds of those injured and they should be shown that often those who retain a deformed limb have much less function than those with artificial extremities. 80 AMPUTATIONS. 3. After the patient has an artificial limb and begins to learn a trade, his work should be such as to fit him to do that which is of most benefit: in the community where he expects to live. For ex- ample: If a mutilé has his limb, and when able to return to work is taken to his home, say in Montana, there to live and be reeducated, he should be encouraged to do mining or farming. If on-the other hand he comes from Massachusetts, he should be taught jewelry work or shoemaking or the like. In other words fit him for the trade where there is the greatest demand. We in America should have such centers of reeducation thoroughly adapted to teach in accordance with the needs: of the community or section. Of course, we must al- ‘ways consider what the mutilé can do and whenever possible he should return to the trade or occupation in which he was most pro- ficient before his disablement. . At the Roehampton Hospital, 5 miles from Charing Cross, Lon- don, there are 900 beds for convalescent amputated cases, and there are always hundreds awaiting admission. This is only one of a num- ber of similar hospitals, and 14,000 cases have been fitted with arti- ficial limbs here and sent out. The manufacturers of the instru- ments work on the premises, and while waiting for the apparatus or learning its use, the men may take up new trades. Sailors come here as well as soldiers and we saw one of the British Navy ‘sur- geons fitting splints. It would seem to be an excellent idea for the Navy to be thoroughly in touch with this work. With our marines in the thick of the fight- ing, we should be prepared to let them profit by all that experience has taught our allies. At Roehampton( an old sailor, J. M. Andrews, who is also a skilled mechanic, is of the greatest aid in advising the men as to their future. He is full of cheer as well as most practical, and goes about and talks with each man and discusses his future occupation and how he can best be fitted for it. Lieutenant Colonel MacLeod, who is in charge, said: Most of the cases should have provisional apparatus before they come here. Up to the present time they have had none, but I believe it will come soon. He said that there had lately been an increase in the number of double amputations—61 such cases in the preceding month. The average stay in the hospital is thirty days for a leg, but less for an arm. Double amputation or joint amputation means, of course, a much longer stay. High amputation of the thigh with only 3 inches of bone left was of no value asa rule. Such a case is treated. as if it were a hip joint amputation. He considers the hip joint amputation apparatus one of the really great things of the war. The patient “sits” in the apparatus quite comfortably and can walk for miles with ease. AMPUTATIONS. ': 81 He says: “Ninety per cent of the amputated cases should before long be self-supporting.” In the matter of provision by the Navy for artificial limbs, the following letter from Captain Miller should be given careful consid- eration: AMERICAN RED Cross, DEPARTMENT MILITARY AFFAIRS, ARTIFICIAL Limge SERVICE, Paris, June 27, 1918. From: Capt. H. W. Miller, 12 Rue Boissy d’Anglas, Paris, To: Surg. William S. Bainbridge, U. S. N., R. F., Hotel Crillon. Subject: Mutilés. 1. The bureau of manufacture of artificial limbs of the American Red Cross has been in operation for over a year. It has made what we hope has been a careful survey of the manufacture of artificial limbs in France, Belgium, Italy, and Great Britain. At the same time we have conducted a workshop, where the past nine months we have been actually manufacturing artificial limbs. As the result we have adopted a type of leg which, although far from ideal, is nevertheless, in our opinion, the best that can be made to-day. 2. The greater part of it can be manufactured’ in quantity. It is of the wooden American type, following on the whole the principles of Dr. Martin, of the Belgian Army, as to statics. It has been adopted by the surgeon general’s office of the French Army and is being supplied to the orthopedic division, A. E. F. Following design of Capt. P. D. Wilson, M. R. C., we are manufacturing for the A. E. F. a type of provisional apparatus which we have found satisfactory. ' 3. The organization and equipment of our workshop has taken considerable time and has been attended with a good deal of difficulty. We beg, therefore, to call this to the attention of the Navy Denekneny: and to make the following suggestions : (a) That this bureau shotlld be prepared to haaihastans samples of any prothetic apparatus which the department desired to have manufactured. (b) On application from the Navy Department to the American Red Cross (to Maj. J. H. Perkins, commissioner for Europe, 4 Place de la Concorde, Paris) arrangements could be made to manufacture such aepeRins in quantity. 4. The Navy Department could send'a personnel to this bureau to be in- structed in the production of prothetic apparatus, such personnel to consist of a foreman (not necessarily a man with previous experience in the artificial- limb business) and an orthopedic surgeon. These men could enter our shop and work there as long as desired. It would give us pleasure at the same time to put them in touch with the various French centers. In our opinion it is essential that the manufacture of artificial limbs be studied in Europe, it being impossible to obtain a correct knowledge of the problem through the American manufacturers, plus a study of the French and English literature on the subject. Much of the latter, although interesting, is extremely mislead- ing and must be checked up with the actual results being obtained here. (Signed ) H. W. MILter. Capt. H. W. Mirier, Chief. 82 . PLASTIC SURGERY. PLASTIC SURGERY. In our enthusiasm over the results being obtained in plastic surgery during the present war, we are apt to regard the work as a recent development and to overlook the fact that there is no other branch of surgery in which such advance has been made during the 25 years preceding the war. Indeed, while antisepsis and asepsis have done much toward making possible the successful treatment of cases re- quiring bone and tissue transplanting, plastic surgery is by no means a discovery of our own day. The ancient Hindus, to whom so many wonderful achievements are popularly attributed, are credited with having performed plastic operations 2,000 years ago. Doubtless this was brought about by reason of the fact that quite a popular form of punishment was the cutting off of the nose. Strange as it may seem, the tile makers, who are reputed to have been a more or less despised class, delegated to themselves the task of nose mending. Presumably. the thought came to these particular artisans as a result of their familiarity with cements and repairs calling for the adhesion of one substance to another. In more modern times, the ingenuity of the most skillful surgeons has been taxed to enable them to remedy congenital defects, such as cleft palate and harelip, or the results of accidents, such as ex- tensive burns, and also deformities from lupus or malignant disease. Pieces taken from the ribs and from other parts of the framework of the body have been successfully utilized. Lane, Brophy, and a host of others were doing wonderful work along these lines before the horrors of war multiplied many times the number of patients requiring such treatment. Restorative surgery, in the broad sense of the term, includes plastic work in many lines, such as bone grafting, the restoring of nerve continuity, tendon transplanting, and the implanting of adipose tis- sue to fill bone or lung cavities; but perhaps the most gratifying results have been obtained in case involving the restoring of the jaw and the remedying of gross defects of face and mouth. ‘Modern warfare has resulted in much deformity, especially hor- rible when the head and face are involved, and it is to plastic surgery that all are hopefully looking for relief for those who have suffered such injury. The injury may be slight and only of cosmetic interest, or so great as to endanger life. Between these extremes there is a multitude of unfortunates who must have repair work performed in order that they may be made more presentable before they can go back either to the fighting force or to civil life and be economically self-sustaining. ; It is evident that one of the great responsibilities with which we shall be faced at the end of the war will be the aftercare which must 82-1 At Queen's Hospital, Sidcup, by Maj. H. D. Gillies: 1, On arrival; 2, wnen healed: 3, after first operation; 4, first stage of second operation; 5, side view of same; 6, second stage of second operation; pedicles returned to scalp, 82-2 ‘PLASTIC SURGERY. 83 be given to those whose injuries require plastic work. While the pre- liminary care of such cases should be started immediately in order to avoid contracture of muscles, stiff joints, and atrophy of tissues, the plastic surgery needed will, in many cases, extend over a period of years. Just as we must make plans now for the postwar care to be given those who have suffered amputation, we must also make ready by plastic surgery to assist those unfortunates who otherwise would be more or less shut off from society. : With this object in view we should establish special departments in certain hospitals or, if the number of cases requires, a special hos- pital where the best dental and mechanical work will be joined with the most advanced plastic and oral surgery. (It would be well if this center could be so located that those taking such courses as are given by the United States Naval Medical School could have the benefit of the clinical teaching.) This assumes that the patients are to be brought back to the United States promptly, but, as stated before, in every case there should be some temporary splint work done immediately and before the men are sent across the ocean. One of the distinct advances growing out of the present war has been the recognition of the need for cooperative work in this field between the general surgeon and the dental surgeon. In the organi- zation of military hospitals the dentist is established as indispensable, and the value of his work along the line of dental repair can not be overestimated. -But the field of the dental surgeon is being greatly enlarged by reason of the vast number of jaw-and face wounds re- sulting from present-day warfare, involving loss of bone, teeth, and soft parts, and cooperation between the general surgeon ‘and the dental surgeon is bringing about such satisfactory results that every means must be taken to encourage and extend this teamwork. The need for such cooperation was pointed out by Surgeon A. M. Fauntleroy, United States Navy, in his report on the medico-military aspects of the European war (1915), and has steadily grown more apparent, until it is now regarded as an essential feature in plastic surgery of the mouth and face. A number of surgeons are de- voting their attention to work in this line and achieving noteworthy results. . The American Ambulance at Neuilly, now Red Cross Hospital No. 1, was one of the pioneers in establishing an enlarged dental department and advocating a close relationship between the dental and the general surgeon. Some of the striking results that have been obtained there have been published, the report of Dr. Faunt- leroy, above referred to, containing at page 100 et seq. an excellent description of the general technique and methods employed. Major Du Buchet, Major Powers, of late, and especially Dr. Hayes and 84 PLASTIC SURGERY. Dr. Davenport, working with Colonel Blake and others, have made distinct advance in this line. In 1915 and again in 1918 I was enabled to see the work at this institution, and while progress is being made in other branches, such as Colonel Hutchinson’s nerve grafting, in no line are more gratifying results being obtained than in this field of plastic oral surgery batted on jointly by the gen- eral and dental surgeons. So valuable has been the work at this center that.a report on it is being prepared, accompanied by an exhibit showing in detail the apparatus used and pictures of the results. This is to be filed as a permanent record with the Army Medical School at Washington, and at my urgent request a duplicate has been promised for the Naval Medical School at Washington. While many other centers are doing excellent work in this field, the ones selected for me to visit as being the ones from which we could learn most were the hospitals at Sidcup, England; Le Mans, France; the Val-de-Grace Hospital at Paris, and General Hospital No. 83 at Boulogne, as well as the hospital at Neuilly. (1) Queens Hospital at Sidcup, Kent, is devoted exclusively to plastic and oral surgery and has accommodations for 500 patients. It is located in one of the most beautiful spots in England, but a short distance from London. Sir W. Arbuthnot Lane, Bart., is deeply interested in the work of this hospital, and recently at the meeting of the American Medical Association at Chicago he spoke of it-as the center of plastic surgery in Great Britain. Major H. D. Gillies, R. A. M. C., the chief surgeon, is a recognized authority on plastic surgery, and most of the jaw cases in the British Army are sent here or to King George’s Hospital, London. (See accompany- ing pictures.) This hospital is divided into five units, as follows: Two units British. One unit Canadian. One unit. Australian. One unit New Zealand. I am told they will be very glad to add an American unit if requested. Casts are taken and the mechanical side is well studied. At pres- ent there are three teams from the United States Army here observ- ing and assisting, each team consisting of one dentist and one surgeon. This institution has an excellent dental department, and there is a great wealth of material for study. The Navy could well take ad- vantage of the opportunity offered and send some of its dentists and surgeons here and to other centers specializing in this work, in order that the marines and sailors requiring such treatment may have the (1 and 2), Condition on admission; (3) adjustable intranasal support carried from a metal cap splint cemented to the upper teeth; iv improvement obtained by operation and insertion of nasal splint; (5 and 6) result of insertion of cartilage graft from rib. Taken three months after operation. (At Queen's Hospital, Sidcup, by Maj. H. D. Gillies.) 84-1 : Private J. P. Horizontal right portion of mandible missing from third molar to canine. Cartilage of larynx exposed. Tracheotomy tube inserted from the side at the casualty clearing station. Shows large flap taken from chest, leaving buccal fistula, which was finally closed. Prosthetic ae was made for the pseud-arthrosis, (At Eighty-third British General Hospital, by Maj. Valadier, 84—z PLASTIC SURGERY. : 85 benefit of the experience acquired by our allies in four years of active war work. (2) At Le Mans, France, Delagéniére is doing excellent recon- structive work for the French wounded, and I was fortunate enough obtain the following description of his methods, which I quote in ull: THE RECONSTRUCTION WORK OF DELAGENIERE. As an offset to the appalling mutilations wrought by the destruc- tive implements of modern warfare, the new and vast experience in surgery has brought forth some wonderful achievements in the re- pair of such injuries. The remarkable reconstructive work of Dela- géniére on bones and joints ranks among the foremost of these con- temporary contributions to surgical resourcefulness in apparently hopeless or insuperable tasks. Credit for the conception of this method of bone repair belongs to Ollier, but for the elaboration of the surgical technique, the formulation of the operative indications, and its introduction as a practical procedure, we are indebted to Dela- géniére. In view of the fact that this important work is hardly Imown as-yet on this side of the Atlantic, it appears desirable to present a brief review of the procedure and its results. Delagéniére’s first report, covering 41 personal observations, pub- lished in the Bulletins et Mémoires de la Société de Chirurgie de Paris, Tome 42, I, 1916, page 1048, dealt with the utilization of osteo- periostéal grafts from the tibia for the reconstruction of bones or the repair of lost bone substance, more particularly for the repair of bony defects of the skull after trephining, as well as in the treat- ment of pseudarthroses of the shaft bones. The fresh osteoperiosteal grafts from the tibia are immediately transferred to the operation wound, without intermediaries of any kind, taking care to handle them only with sterile compresses or instruments. The tibia is treated simply by rapid skin suture over the denuded bone surface from which the periosteum has been stripped, and a small drain is. left under the skin for 48 hours in order to guard against the forma- tion of a hematoma; the wound heals in 8 to 10 days, without com- plications. The graft must be transferred without delay to its new position in the interest of perfect asepsis. The employment of anti- septic agents is contraindicated as interfering with the vitality of the graft. As far as possible, the two surfaces of the graft must be in contact with living tissues. While this condition is easily met with in the closing of bony defects of the skull, more serious diffi- culties are encountered in the case of the extremities. The entire graft must be well covered with skin in order to guard against necrosis and sequestration of the uncovered bony portions of the grafts. 86 PLASTIC SURGERY. About a year later Delagéniére discussed the repair of bony. de- fects and the reconstruction of bones by means of osteoperiosteal grafts from the tibia on the basis of 118 personal observations. (Bull. méd. chirurg. du Mans et de l’ouest, Tome I, No. 6, 1917.) The results in the series of 118 cases were as follows: Fifty-four cranioplastics, with a very favorable outcome in 44 cases; 7 good results and 1 failure through elimination of the graft; a second operation proved highly successful. Of 27 grafts for pseudarthrosis of the inferior maxilla, with loss of bone substance, 10 had an excel- lent permanent result; in 7 cases, not completely healed at the time ef the report, the outlook is favorable; satisfactory results in 2 cases, partial results in 3, and no success in 5 cases. Delagéniére’s 21 grafts for pseudarthrosis with loss of bone substance in the shaft bones yielded 15 good results, 3 partial results, and 1 recurrent pseudarthrosis, requiring a second operation; 1 result was zero, due - to complete elimination of the graft. Finally one patient, a chronic inebriate, died of chronic septicemia three months after the opera- tion. Three bone cavities were closed by means of grafts, with a favorable outcome. Sixteen grafts for reconstruction of the bony framework of the face were entirely successful in 14 instances and partially successful in the remaining two cases. Conditions in the facial region are espe- cially favorable for the healing of the grafts, which can be placed in living tissues where it is easy to avoid dead spaces and to secure good hemostasis. Failure is accordingly rare, and almost invariably due to the opening of a natural cavity of the face. The bony frame- work of the nose can be entirely repaired by means of these osteo- periosteal grafts. It is emphasized by the pioneer worker in this promising field that the indications for the applications of osteoperiosteal grafts are extremely numerous and varied, and will constantly increase when once the procedure is adopted as a routine method. In his last report, published in the Journal de Médecine, volume 89, 1918, page 81, at which time Delagéniére was enabled to base his conclusions on altogether 159 observations, he points out that any missing portion of the bony framework of the body cah be repaired and recon- strusted by means of osteoperiosteal grafts. It is perhaps superfluous to comment upon the marvelous vista opened up in the formerly so discouraging treatment of maimed and mutilated warriors. The results obtained through this procedure are lasting, so that. the function of any bone can be restored with the assistance of these grafts. Summarizing, it may be stated that the results of plastic work on the skull are excellent and always obtainable, provided the correct Private P, Fracture of inferior maxilla. One inch of left ramus pulverized; imme- diate suturing and insertion of flange splint to hold jawin position. Bone reformed completely, notwithstanding that root of molar tooth was subsequently discovered oe final X-ray was taken. (At Eighty-third British General Hospital, by Maj. aladier.) : 86-1 Private J. P. Fracture of superior and inferior maxilla; extensive loss of tissue; immediate suturing. Removal of scar tissue and formation of angle. Teeth in- serted. (At Eighty-third British General Hospital, by Maj. Valadier.) 86-2 J Private W. S. Premaxillary bone missing, both antra foul, shattered and septic Fracture of left ramus. (At Eighty-third British General Hospital, by Maj. Valadier.) Private J.S. Fracture of inferior maxilla; symphysis missing; two molars and bicuspid standing. Angle band and bar inserted to retain arch as far as possible; flap from neck taken to fill gap and artificial hare lip made. Hare lip operated and teeth inserted. (At Eighty-third British General Hospital, by Maj. Valadier.) 86-3 Private W. Fracture of inferior maxilla; nose shot away. Ninth and tenth cartilaginous por- tion of rib inserted in forehead in 9 weeks; flap, all of cheeks, turned down; in 9 days pedicle severed and skin graft over space where flap was lowered. Prosthetic appliance made to help shaping of nose. (Final result of this case has never been published.) (At Eignty- third British General Hospital, by Maj. Valadier.) 86-4 PLASTIC SURGERY. 87 technique is adopted and properly carried out. A favorable outcome may be anticipated in. practically all cases. In pseudarthrosis of the lower jaw, where the grafting method has been definitely introduced and established, the causes of failure are more numerous on account of the site of the graft, which is more accessible to infection. However, the actual results already equal 72 per cent of complete success, and this percentage will steadily grow. In bony defects of the limbs conditions are similar to those obtaining in the case of the maxille, and the results are analogous, but even better, with 85 per cent of successful cases. Practically constant results, equaling a percentage of 100, are ac- complished by osteoperiosteal grafting in the repair of bony cavities and in the reconstruction of the face. With special reference to the latter, the transformation by the operator’s skill of those unfortu- nates whose countenance has lost all semblance to humanity through ’ the frightful ravages of bomb and shell is little short of miraculous, and for a variety of considerations, ethical as well as medical, must be regarded as one of the greatest triumphs achieved by the beneficent art of surgery. (3) The Val-de-Grace Hospital, at Paris, is one of the largest in France. Here and at the Hopital St. Louis Dr. Hippolyte Mores- tin is accomplishing excellent plastic surgical results. He has at the Val-de-Grace a museum containing a most interesting and instruc- tive collection of wax casts and slides showing not only the work in the present war but what was done during the war of 1870 and 1871. The contrast between what was then the high-water mark of achieve- ment and what is now being accomplished is encouraging in the highest degree. (At the University of Lyons also a large number of casts and pic- tures are on exhibition and show the remarkable results obtained by the French surgeons at this center. The collections of casts, pic- tures, and drawings at these centers of plastic work are well worth study by those about to take up this line of surgery. They will be invaluable records for the future.) (4) At No. 83 British General Hospital, Boulogne, I met Major A. Charles Valadier, R. A. M. C., who is in charge of the oral sur- gery. He is an American graduate physician, and before the war was a practicing dentist in Paris. He is now an officer in the Brit- ish Army and has 50 beds in the hospital where he does special jaw work, some of which I witnessed. The accompanying illustrations show the results of his skill. He attributes part of his success to the fact that he at once puts in an apparatus for the jaws so that the parts will not contract badly. He said: “Save all the bone possible. Whenever any piece is attached at all, save it. I would rather chance its sloughing out than remove it. Early in the war 88 PLASTIC SURGERY. I needlessly sacrificed bone, but do better now.” He uses only sterile water for dressings and mouth washes, irrigating every hour under hand-pump pressure. His collection of wax models, pictures, and stereoscopic photographs in color is really remarkable. - In certain cases of injury to the face and jaw, it may be found that the defects are too great for immediate repair or that the con- dition of the patient precludes operative treatment. Sometimes it takes months or years to do the necessary work ‘because it must be done in stages. For this class of cases, other means of relief must be found, and this need is being met by mechanical substitutes for portions of the face. « The American Red Cross in Hagics is doing excellent work in this line (see accompanying pictures) ; also the Third London Gen- eral Hospital. Striking are the accompanying examples of plates made for mask- ing facial defects at the Third London General Hospital by Captain Derwent Wood, R. A. M. C., the well-known sculptor. Case I: Driver F. Skull wound April 25, 1915. Admitted May 28, 1915.. No operative treatment. Picture 1. Deformity after shealing. Picture 2. With plate in position. Case II: Trooper E. Gunshot wounds face and arm, May 13, 1915. Admitted September 2, 1915. Plastic operations by Capt. Richard Cruise, R. A. M. C.,, September 29, 1915; again October 8, 1915, and finally October, 27, 1915. Con- dition of patient greatly improved by these extensive repair operations. Mouth closed off from nares, antrum sinus closed, and large opening into left nasal cavity repaired. Pictures 3 and 4 show unsightly deformity even after excellent surgical restoration. Pictures 5 and 6 show facial mask which enabled patient to return to his former occupation as a taxicab driver. . Captain Wood described his methods and showed me many casts and masks. The work is of great value and I therefore give largely in his own words a description of the process. PROCESS. (1) Casting patient's face.—It is essential that a good fit on the edges of the plate should be secured ; to this end a plaster mold of the face is obtained. In the case of*driver F., and in consideration of the nature of his wound, I filled the cavity with his usual dressing, cotton-wool, covering this and his left eye and eyebrow with goldbeater’s skin, bandaging all portions of his head that were not wanted in the mold; his nostrils were blocked with cotton-wool, the patient during the casting breathing through his mouth and being seated with head thrown back and pillowed on a box. After the exposed portion of face has been oiled, the plaster is mixed with tepid water and applied. In five minutes the mold is removed, bandages stripped, and the patient cleaned up. (2) Modeling.—The mold having been obtained, it is dried, French chalked. and a clay or plasticine squeeze is obtained from the mold, giving a positive Views of masks made by Mrs. Ladd, of the American Red Cross, Paris. The masks at the top are taken direct from nature; the lower ones are the remodeled faces. 88-1 ‘S]d¥q ‘SSO1D pay UBJJaWY 84} JO ‘PpeT ‘sAW Aq ope eovs OU} JO Sal}WIOJep Jol SySBI 88-2 Masks made by Mrs Ladd, of the American Red Cross, Paris. Driver F. 88-3 eTrooper E. 88—4 Showing the use of masks to conceal disfigurement. 88-5 Disfigurement from wounds concealed by face masks, 38-6 TRENCH FEVER. 89 model of the patient’s dressed wound and the surrounding healthy tissues, This is fixed to a board on a modeling stand, and a sitting from the patient with undressed wound is obtained. Modeling now commences, and such art as the sculptor may possess is brought to the test. A reconstruction of the wound in every detail is established, taking care that the depths and widths of the wound are accurately measured and modeled. The sculptor having completed his model, he proceeds to cast it and procures the plaster positive of the wound and its surrounding structures. Another sitting is obtained, and the portions which are to be hidden eventually by the metal plate are modeled in clay or wax, the edges being blended to the uninjured portions of the face, thus effec- tively masking any trace of wounds. This is once more molded in plaster, and the,edge of proposed plate being marked on the negative, a cast is obtained, edges are trimmed to marking, and the model is ready to have the artificial eye fitted to the lids; this is done from the back of the model. The plaster eyeball is dug out, the requisite thickness of lids carefully worked down, the glass eye placed in position, and the edges of the lids made good with thin plaster. (3) The plate——The model is now taken to the electrotyper, where an exact reproduction by galvanoplastic deposit is made in virgin copper # inch in thickness. This is finally well coated with silver. Thin bands are soldered in on the back to clamp the eye in place. The plate is again fitted to the patient, strong spectacles are adjusted at the requisite angle to give a well- distributed pull on the plate. In the case of a large plate being used, an elastic band around the back of the head is necessary. : The final sittings are devoted to the pigmentation of the plate. I have found a thin coating of cream-colored bath enamel a good preparation for flesh color matching, as it leaves the oil-color mat when dry, which is essential to the illusion of a good blending of plate with face; should the patient have shiny skin, this is easily obtained by varnish rubbed down to match the skin. I have tried false hair on eyelids and eyebrows, but they will not stand the weather, and have adopted tinfoil split with scissors and soldered into lids for the eye, and for the eyebrows pigment applied to the modeled forms. TRENCH FEVER. A vital medical problem for a4 long time confronting those respon- sible for the health of the armies abroad has been what the British have termed “P. U. O.” (pyrexia of unknown origin). Compara- tively recently the louse has been definitely incriminated as the carrier of the disease, and through this discovery a long step forward has been taken toward the elimination of much serious illness and disability resulting from this cause. In June, 1918, I was present at the conference on this subject, held at the headquarters of Major General Guise Moores, D. G. M. S., and was privileged to hear the discussion between Lieutenant General Burtchaell, C. B., chief of the medical service of the British forces in France, and Colonel G. A. Moore, C. M. G., D. S. O., D. D. M. S., who had been given this important problem to study practically in the field and make a report. In describing his work he spoke first 93696—19——7 , 90 TRENCH FEVER. of the cases of trench feet which developed early in the war and which called for vigorous measures: First we learned what caused the trouble and then took steps to check it, and now we prevent it altogether. An official order prescribes definite detailed care of the feet, such as clean, dry socks and rubbing the feet thoroughly with oil at stated periods. This treatment has put an end to trench feet. We can now stop trench fever by keeping the skin clean and disinfecting the clothing properly with the Foder-Thresh machine, By doing this once every 12 to 15 days the lice can be killed off. Nits are more difficult to kill. They come on the hair in the pubic and axillary regions, about half to a quarter of an inch from the skin. The question of louse extermination is the main one to-day, medically considered, in relation to the trenches. Frequent bathing ‘and the rubbing of a small amount of blue ointment into the hairy regions of the body, together with clean clothes, will eliminate the scourge. To-make such sanitary conditions possible for 4,000,000 of men is a stupendous problem. Now that the importance of the louse as a factor in the transmis- sion of disease is being recognized, it becomes evident that the eradi- cation of these vermin is one of the most urgent problems to-day of the medical officers in the Army and Navy. At the beginning of the war many cases of disease not conforming to any known type were classified under the heading of “ P. U. 0.” Further. experience showed that three-fourths of these cases gave a fairly definite symptom complex and could be safely included under the term “trench fever.” There are two types of this disease; one, the “short” type, lasting from 5 to 10 days, with a slight remission; the other, the “long” type, sometimes lasting several months, being recurrent in character. This disease is an important source of dis- ability, as it is responsible for a large percentage of hospital admis- sions in all the armies. Major Swift, for example, states that 20 per cent of the admissions to his hospital are definite cases of trench fever, and in some of the armies of northern France the percentage has risen as high as 333 per cent. While the ultimate prognosis of the disease is good, it is very likely to be followed by general debility and disordered action of the heart (D. A. H.), thus incapacitating a large number of men for active service. It will readily be seen, there- fore, that the prevention of this disease is a matter of the first impor- tance. Thetrench-fever investigation committee, of which Major Gen- eral Sir David Bruce, K.C. B., M.D., F.R. S., A. M. S., is chairman, has definitely established the fact that this disease is louse borne. When the louse feeds upon a patient with trench fever its intestinal canal becomes infected, and if then the excreta are deposited upon the skin of a new victim the organism gains access to the blood of the patient through scratching, and the disease is transmitted in this way. The problem of eradicating trench fever, as well as typhus and relapsing fever, thus becomes very largely the problem of eradicating the louse. TRENCH FEVER. 91 That the task is not an easy one will be realized from the fact that the trenches on all the fronts are louse ridden from one end to the other. The transport service has to face the same problem, inas- much as at present on some transports the percentage of lice is high on disembarkation of our troops in France. Colonel Seiler and Lieutenant Colonel Strong, of the Central Research Laboratory at Dijon, are working on this problem.and have collected considerable data. Lieutenant Colonel Darrach, United States Army, with whom I talked at Etretat, was much impressed with the importance of the subject and felt very strongly that as in one instance 90 per cent of the men on a certain transport were found to be infested with lice, the Navy as well as the Army should take up the matter. He said that a number of men in his unit had become infected with trench fever after handling the clothes of the patients, but that since that time they have been more careful about protecting these men. When the problem of louse eradication is considered, it is to be remembered that the soldier himself is the chief source of infesta- tion. As Dr. Peacock says, the louse “is a parasite which is de- pendent utterly upon man’s blood for sustenance and man’s body and clothing tor prolonged, prosperous longevity and reproduction.” They are spread chiefly by contact, crawling from soldier to soldier, and leave the human body only when the surroundings are warm aud moist, as in bed. The louse can live 10 days at longest when unfed, and according to Warburton the nits can remain dormant when away from the body for not more than 40 days. The nits may survive freezing, but when they are kept dry and away from the body they usually begin to shrivel up in a few days. The eggs are laid chiefly in the seams of the clothing, being found in greatest numbers in the underclothing and in the fork of the trousers. They are laid also on the body ‘hairs, and the infested parts, or even the whole body, may have to be shaved in order to prevent a rapid reinfestation. Frequent bathing and at least a weekly change of underclothing are usually sufficient to prevent infection, when there is no overcrowding. Under such adverse conditions as exist in time of war among men in active service, the problem becomes a very difficult one. When circumstances are such that the men can not be provided with adequate bathing and laundry facilities and disinfectors are few in number or altogether lacking, palliative measures must be re- sorted to. Many of the lice and nits can be killed and removed by the men themselves, especially in warm weather, when the clothes can be taken off, hand-picked and thoroughly brushed or beaten. Under- clothes can be immersed in boiling water and the outer garments can be baked in the sun or in an improvised oven, or the seams can be ironed or passed along a jet of steam from a kettle of boiling water. 92 \ , TRENCH FEVER. Insecticides are useful in killing the lice themselves, but usually do not affect the nits. The multitude of remedies suggested for this purpose proves that the ideal insecticide has not yet been wound. Creolin,1 percent solu- tion for steeping or spraying clothes or from 8 to 10 per cent solution vaporized, is apparently the most satisfactory preparation, as it is noninflammable, nontoxic, cheap, and not injurious to fabrics. Cresol-soap solution is also very useful and may be used for bathing, as well as for soaking clothes, including boots and leather articles. Naphthaline 96 parts, creosote 2 parts, and iodoform 2 parts, known as N. C. I. powder, has been extensively used in the British Army for dusting on the clothes and body, and was recommended by Peacock as the most satisfactory insecticide which he had tested. The measures above described will do much to mitigate the evil. and when thoroughly carried out, being controlled by frequent in- spection of the men, will give excellent results. When a unit comes out of the trenches, the process of freeing the men from vermin can be carried out more thoroughly and on a larger scale. Hot dry air or steam, applied by various methods, has proved most efficacious in accomplishing this purpose. G. H. F. Nuttall, M. D., Ph. D., Sc. D., F.R.S., has done consider- able research work on.the viability of lice and nits under varying conditions of temperature, moisture, etc. His experiments prove that both lice and nits are killed by a moderate degree of dry heat, by 55 C. in five minutes, or by 65° to 75° in one minute. He advises that in practice the infested clothing should be exposed to a tempera- ture of 60° to 65° for 15 minutes, in order that every part of the garments may be penetrated by the hot air. Both lice and nits are killed in five seconds when immersed in water at 70 C., but in practice the infested clothes should be left in the water for one or two minutes at this temperature, or for 10 minutes at 55 C. They are killed in- stantly by moist heat at 80 C., and the period of exposure in a steam disinfestor, when the clothes are not too tightly packed, should be about 15 minutes. When it is impossible to obtain apparatus especially designed for the purpose of disinfestation, it is almost always possible to improvise more or less simple apparatus which is fairly efficient. An ordinary baking oven or a brick superstructure, placed over a kitchen range, will furnish dry hot air of the desired temperature, or a packing case or barrel resting on a sheet-iron plate with a thin layer of earth may be used over an out-of-doors fire. A very simple and efficient hot-air hut has been devised by Captain Harold Orr, C. A. M. C., and modified by Grant and Peacock. Plans for the various models of this hut may be found in Nuttall’s excellent pamphlet on Combating Lousiness among Soldiers and Civilians. TRENCH. FEVER. 93 In disinfesting barracks, railway carriages, etc., steam is the most efficient means that can be used. Clothing, blankets, and other equip- ment, if hung or packed very loosely, can be sterilized at the same time. Steam disinfection huts or disinfecting vans or trains, the latter having the advantage of mobility, are extremely useful in dis- infesting outer garments and blankets. Whenever possible, it is, of course, more satisfactory to use the more elaborate apparatus especially designed for the purpose of disinfestation. Numerous types of hot-air and steam disinfestors have been devised and of these perhaps the most extensively employed have been those made by the Thresh Disinfector Co., 4 Central Build- ings, Westminster, London, 8. W. They manufacture a fixed type, to be used in hospitals and disinfesting stations, a horse-drawn type, and one mounted on a Foder steam lorry, commonly known as the Foder-Thresh machine. It is highly important in the use of any disinfector, from the sim- plest to the most elaborate, that it should be properly managed, as carelessness in any one detail may render the whole procedure value- less. If the clothes are too tightly packed, or if the temperature does not reach the necessary height, some nits or lice will survive and the garments will be quickly reinfested. If the clean garments are not kept strictly separated from the verminous, or if the per- sonnel attending to the disinfection are themselves infested, the same result will follow. Thoroughness and attention to detail are absolutely essential. Experience with each particular disinfector will enable the operator to standardize the load which it can treat at one time. The problem of ascertaining the temperature in a dis- infector has proved to be a rather difficult one. Nuttal considers the method of Captain C. G. L. Wolf, R.A.M.C., to be the most practical when it is desired to record different temperatures. In this method advantage is taken of the fact that various substances have different melting points. Any colorless substance having a melting point of the desired temperature is mixed with a minute quantity of any aniline dye and placed in a small glass tube sealed at both ends. If the dye is finely divided, the mixture will be practically colorless, but when the substance melts it will instantly take on the color of the dye. Where a complete disinfestation plant can be established, with baths and laundry facilities, freeing the men from vermin is com- paratively simple. The men are usually treated in groups of 20 to 100. The station is divided into two sides, clean and unclean, these two sides being separated on the outside also by a high wall. The men strip when they come in and hand all of their belongings to an attendant, to be taken to the disinfestor. The men then bathe, are shaved or receive a hair cut when necessary, and after due precau- 94 TRENCH FEVER. tions are transferred to the clean side where they receive their disin- fested garments. As far as possible, care should be taken to keep the clean men from mixing with the unclean, and’ new men coming into a unit should be inspected before being allowed to come into contact with the other men. It seems to me that the importance of this question can hardly be overestimated, and that the proper working out of the problem will result in an incalculable i increase in efficiency in both the Army and Navy. The following statistics, furnished to me by General Moores, show the need for vigorous measures to prevent the spread of this disease among the fighting forces. They are the figures relating to sick admissions in casualty-clearing stations for the second British Army in France for the period of 12 months ending April 6, 1918, and show over 25,000 cases of illness traceable to this source. P; U. O., (mostly trench fever) ___ ~ 15, 392 Trench fever ____ u 5, 244 Myalgia (mostly trench fever) 4, 755. Rheumatism (mostly trench fever) a om 633 Debility (mostly result of trench fever, late) --------------.-----____ 2, 535 Cardiac (mostly result of trench fever, late) -----------_------------- 2, 587 KEY TO DIAGRAM SHOWING THE PROCESS OF EVACUATION OF CASUALTIES AND THE DIFFERENT COMMANDS OPERATIVE IN EACH SECTION. I. Collecting: 1. Trenches. (a) Firing line. (bv) Support line. » Casualty. Regt. S. B.’s dugout. Regt. Med. orderly’s dugout. . Communication trench. Trench stretchers used. Light cases walk. 6. Regt. aid post .(M.. O.). First aid and hot drinks. 7. Field ambulance. (a) Advanced dressing station, bearer subdivision. (bo) H. Q. and tent subdivision. (c) Collecting station for light walking cases. 8. Surgical team, for immediate operation. 9. Divisional rest station. 10. Casualty clearing station. It. Evacuating: 11. Railroad. 12. Canal (12A barges). 138. Railroad. 14. Base and port. 15. Stationary hospital. 16. General hospital. 17. Convalescent camp. 18. Hospital ship. ne re DIAGRAM SHOWING THE PROCESS OF EVACIATION UF CASUALTIES, 4, AND THE DIFFERENT COMMAKDS OPERATIVE IN EACH SECTION), J G : ne) Momin asi ds eae i : i, Gone q sh lesao teed emule aa "Gog, men TCT amr A RRM inky Mei ne BE i ee Tine A { vy Garwehies . + Me Aue Na ve 2 “Cermal’ly . Y 1. ff s. Augh |S '> dug, nll ¢ the ‘tied a Real Mel osderty's i } 5. Commune sanele {i pera ward inetel. Pst Caots vale stilleny. Me 4 GoM eal bial Pool ONO) NLS. | i Cie se of \ Be Disssuees Mey he aie Pie | } NCA. “ott Woy, + iv, iin ys , ui Wang. \ | ‘| ‘Gol Fel fete fox Cig ht ot bsney cours d 2 | \ if a eo oe . OL a, | a. Wiisineal” eal ataleesee J SCorfeas! | AA Jan. ‘Castealty elicising slestion | is fo Weil lreest Mime | t { | Ag x a Teese dy | tz (ONT 0. lees Rete BAA } re 4 115. Merlot. { = | | | j |, DNA, Ie | Fy Bars and frond” i S 4 Ben | ? J as, 2 Sevassarhiong ie a 15, Maleoneey Maspital . . Mofey {o? , ” ie rw \ acs | j 5 . fh 16 General? Mosfotel « 2 ae, | De Raa lesan ARC vale Ye 7 tow ra. deeasfital’ slaps 5 WM, Fawec frost ~e io i. Deoalvalest (or vera WHE s NSaystinny CS foe ti i , re eenbiol Her fs 5 Kasfiteot (as Z 94 TRENOH FEVER. 95 III. Distributing: 19. Home port. 20. Hospital for cases unable to travel. 21. ©. C. S. for light walking cases. 22. Central hospital, near patient’s home. 23. Hospital for special cases. 24, Auxiliary hospital, draining central hospital. 25. Convalescent depot. 26. Patient’s home (sick leave). KEY TO ABBREVIATIONS. . M. S.—Director general medical services. . S.—Director medical services. . M. S.—Assistant director medical services. . M. S.—Deputy director medical services, . 8S. (L. of C.)—Director medical services, line of communication. . D. M. S.—Deputy assistant director of medical services. . C.—Inspector general communications. AOOoPoUD A Laas CARE OF THE WOUNDED FROM FIRING LINE TO CONVALESCENT CAMP. SURGERY OF THE FORWARD AREA AND TRANSPORTATION OF THE WOUNDED.. A complete description of a trip which, through the courtesy of Director General Goodwin and his aides, I was enabled to take in order to observe every step in the history of the wounded man from the moment of receiving first aid until he was either restored to military duty or discharged as unfit for further service, would be full of human interest, but would serve no useful purpose in this report. However, some observations made at certain points in that trip may be found to be of practical value, and these are recorded as briefly as possible. The trip itself began at the trenches in the British zone and progressed, step by step, from the stretcher on which the wounded man was borne from the battle field, through regimental aid post, advanced dressing station, field ambulance,. walking wounded post, main dressing station, casualty clearing station, ambulance train, stationary hospital, ambulance transport to England, ambulance train to the base or special hospitals, and finally to the convalescent camps. 4 wot oo Pa Po 5 arias Se o: (ee | vq bh, Sue) ose) eS ee ga) SH ae Bi eet Shit + ES) Ss a? BES foes 5 i “ S veg ES BS (oat) pee as) ae aE = iP ee | ee a oe5 a. Toe oe 4 v8 \ | aos. = wo aan Pee eee es a 2 1) : ( re 1 2 a5 - cer sis caer ! I ow ila Es Cah eet es rs ae es : 5 4 e \: AS Soil | = f yer Sortie esol) Geren. "ICOdMOVIG i Nel a Ae Nw aALIC 157 CONVALESCENT CAMPS. 157 abandoned, but not before it had created a great stir and pointed many a serious lesson. The diseases so charged as being due to exposure and dirt were: 1. Trench feet. 2. Infection of cutaneous tissue. A large number of cases under these two heads are undoubtedly due to trench fever, which is P. U. O., or pyrexia of unknown origin but now thought to be carried by the ‘| louse. 5. Skin disease due to irritation. 6. Dental caries. Of the 9,503 men who passed Gee this camp in 1917, 42.4 per cent were returned to full military duty; 19.4 per cent to the com- mand depot for further hardening (almost all of these later go over- seas for full military duty) ; 28 per cent to employment (not over- seas); 6.3 per cent to other hospitals for treatment; 2.62 per cent invalided out of the service; 0.03 per cent (8 men) died. A recent development here, and one which is a step in the right direction, is the “Khaki College,” established in February, 1918. A near-by technical school, St. Anne’s, has arranged a number of courses, each extending over two months, covering the fields of com- mercial training, languages, mathematics, arts and sciences, any two of which a man may undertake. There are also evening classes in commercial branches and music at the camp itself. This is a very valuable addition to the hospital and one which is receiving enthusi- astic support from the patients themselves. Colonel Barron said: “ We have found the Khaki College started here is popular because a man can learn Greek, or how to draw carica- tures, or wood carving, and not be bothered by well-meaning visitors inquiring whether he is learning a new trade for after the war. Our professors are all drawn from the staff or patients. Any subject under heaven is taught excepting military subjects.” 3. Myalgia. 4. Rheumatism. y SUMMERDOWN MILITARY CONVALESCENT CAMP AT EASTBOURNE. (Lieutenant Colonel J. S. Bostock, R. A. M. C., ©. 0.) General Goodwin said: “A trip to Eastbourne Camp is most interesting and instructive; a meeting with Colonel Bostock is an inspiration. He is an institution in himself.” And after my visit to Eastbourne I agreed with him. The camp is delightfully situated on the downs near the sea, and everything possible i is done to make the men forget the battle line and take a normal view of life once more. After noonday there are no 158 CONVALESCENT CAMPS. guards about. Equipment is furnished for every sort of game—base ball, bowling, fishing, golf, tennis, boating, billiards, marbles, cricket, etc. There are handball courts and squash courts and every ‘kind of healthful sport is encouraged. Near by there are some links where the men can caddy if they desire. This gives them some pin money, as well as out-of-door life and exercise. The whole atmosphere of the place is that of a club or fraternity. Here, as at Blackpool, there is a “ Welcome Hut” at the entrance, where, on arrival, men are given a good meal. There are flowers all about and an atmosphere of cheer. Notices are posted on the walls of good times coming. The camp has well-equipped writing and recre- ation rooms, also a theater. The treatment consists of: 1. Reeducation and massage. 2. Remedial exercises under medical officer in gymnasium. 3. Physical therapy, proper; army gymnastics. Three thousand six hundred men were at this camp at the time of my visit. They wear a regulation convalescents’ uniform of dark blue with red tie. There is a blacksmith shop, where, with volun- teer labor, considerable money is saved. On the farm, all the plow- ing is done by hand by the men for the sake of the exercise. This year they are getting all of the vegetables for four months, for the entire place. There is a great variety of small flower beds which are voluntarily kept by the men, and there is much competition among them, each group striving to make its hut entrance the most attractive. The basket making and other industrial work is in charge of Miss Samuel. She and the men divide the returns. Out of her half, she keeps up the work in manual arts, the art shop, and book bindery. A fortnightly magazine is published by the men, giving all the camp news. Economy is impressed upon the men by example. Nothing useful is wasted. The grease from plates is collected and used for making soap and- glycerine. They have saved 50 tons of pure fat in two years. Even the leaves from the tea are saved (a by no means in- considerable item in a British establishment) and mixed with coal dust and used in the fire. Colonel Bostock says: “ We need 3,600 calories daily for each man. They must have plenty of proteid to refit them for fighting.” He thinks there should be two types of convalescent hospitals; one for men who can probably be sent back for military duty in two months, the other for those who require longer and more technical treatment. This latter type would be more of an auxiliary hospital. The ordinary convalescent remains here from 27 to 30 days, while severe cases remain occasionally for a year. : EASTBOURNE. Mess Hall. 158-1 Eastbourne, The band, i Bs Eastbourne. Patients from convalescent camp at work. 1658—z cn vl i é = Wa) Eastbourne, 159 CONVALESCENT CAMPS. 159 “We do not use the Red Cross sign; we found it of no value as a protection. The Red Cross brassards were used in the field ambu- lance for the first three days of the war, then done away with and never since used by us. The Germans use them always.” All through this institution there is apparent a carefully studied effort to make the men feel at home, cheerful and happy and proud of their camp.. Many of them wear away rings bearing the name or picture of the place, and there is a bond of interest and fellowship, even in the trenches, among those who have been here. a oO Physical training of mutil Hospital’ Bon Secours, Rouen. 161 REEDUCATION FOR THE DISABLED. John Galsworthy says in his foreword to the report of the second meeting of the Inter-Allied Conference on the aftercare of disabled men, held in London in May, 1918: “In every township and -vil- lage of our countries, stricken heroes of the war will dwell for the next half century. The figure of youth must go one-footed, one- armed, blind of an eye, lesioned and stunned, in the home where it once danced. The half of a generation can never again step into the sunlight of full health and the. priceless freedom of unharmed limbs.” ’ Before so tragic a picture of the ruin wrought by war, the heart at first utterly fails. But youth still has some gifts and many powers, the more to be cherished because of what is gone. Science, educa- tion, charity in the Bible sense, gratitude for heroic sacrifice must rise up together to work for the stricken ones who return to our shores. Ours is the task of teaching them to look not at what is lost but at what remains and of helping them so to use the unharmed faculties and muscles that they shall become not mere onlookers but active participants in the great battle of life. There will be those disabled through amputation, through loss of sight or hearing, through facial wounds and through neuro-organic or neuro-psychic wounds, and many others who must have special care and training. France and Britain recognized their. responsibility in this field early in the war and we, the newcomers, may well learn from them and Belgium the lessons that four years of experience have taught with the idea of ascertaining what is the utmost we can do toward the physical and economic rehabilitation of those who return to us cripped and maimed. Terribly significant is the fact that no country now at war per- mits the publication of official statistics as to the number of amputa- tions performed, but in every center where the wounded are treated one hears the same story. Early in the war there was much sacrific- ing of limbs which more recent developments indicate could have been avoided. Even with the improved methods now in vogue there is necessarily a large amount of amputation, and public sentiment is being aroused to solve the problem of how to give to those who have suffered loss of limb such aid—surgical, mechanical, and educa- tional—that they may be returned to the ranks of the self-support- ing. To this end, there must be the closest cooperation between the 161 162 REEDUCATION FOR THE DISABLED. surgeon, the artificial limb maker, and those who shall be entrusted with the economic reeducation of men who are unable to resume their prewar occupations. In deciding the point at which a limb should be severed, the good surgeon will bear in mind not only the question of the speedy healing of the wound, but the type of arti- ficial limb best adapted to the needs of the patient in his future oc- cupation and the kind of stump which is necessary for the fullest use of such apparatus. Comparatively few of our surgeons now car- ing for the wounded are fully informed as to the work in reeduca- tion already being done in France and Great Britain, and the first step which should be taken by those in authority should be the im- mediate disseminating of this information among our Army and Navy surgeons and hospital corpsmen. The inspiration which will come to them through a full realization of the possibilities in the future for the disabled men will enable them to encourage and cheer the patients and bring an atmosphere of hope to replace the dark- ness of despair which comes when a man looks forward to a future of enforced idleness and dependence. The psychological effect can hardly be overestimated and the earlier in his convalescence that a patient is furnished with provisional apparatus, taught to use it and his unharmed muscles to the fullest extent, and aided and encour- aged in selecting a new trade or profession in case he is unable to take up his prewar occupation, the more quickly will he recover physical and mental health, As stated in another part of this report, fis subject of the con- struction of artificial limbs has been given much consideration and study by all of the warring nations, and each has produced apparatus more or less satisfactory. The American Red Cross has perfected a leg with a centrally controlled knee, which is generally considered the best so far evolved. It is lighter than the others, and has better action at the knee and ankle, and some motion at the junction of the toes and tarsal bones. The English arm is considered best for the workingman as it is stronger and lighter, while for clerks the more complicated French arm is better adapted. For years there will be much work in this field, as we must furnish not only the best possible provisional and permanent appa- ratus, but also keep these artificial limbs in repair. There is some question as to whether this should be done for the Government by private enterpise, or whether the Government should establish cen- ters under its own control. Whichever course is pursued, it is im- perative that the limbs be made and fitted by skilled workmen at the center where the patient is, in order that there may be close cooperation, as said before, between the surgeon and the artisan. In former days men, who had lost limbs in the service of their country, were given such surgical treatment and meager equipment Hospital Bon Secours, Rouen. Physical training of mutilés. Lord Mayor of London and group of delegates at the Interallied Conference, London, May, 1918, 162-1 . L. C. Cook, aged 29, wounded at Verdun, Both forearms amputated. L. C. Writes legibly by means of. wooden hand and jointed thumb after a three months’ course of reeducation. 162-2 I. FUNCTIONAL REEDUCATION. 163 in the way of artificial limbs as the times afforded, and then turned back upon'the community with a pension or placed in a soldiers’ or sailors’ home. In our day no enlightened nation would be satisfied with so limited a course. Economically, the waste of man power would be unthink- able; ethically, the failure to recognize a wider responsibility would be inexcusable. The heart of the world, stirred by the tremendous ‘sacrifice that youth is making, demands that such poor reparation as is possible be made. In addition to surgical care and artificial limbs, the disabled man must be given, first, functional re- education, in order that he may make the best. possible use of the unharmed muscles and of the new prosthetic apparatus; and, second. vocational reeducation in order that he may become economically in- dependent in case he is not able to return to his former occupation. I. FUNCTIONAL REEDUCATION. Experience in England and elsewhere has already shown that it is unwise to leave this reeducation to the time after the wounds have entirely. healed and the patient is ready to leave the hospital. Habits conducive to permanent helplessness and reliance on others, difficult of eradication, have then been formed, and the self- assertion and energy of a man who has once resigned himself in despair to what he deems his lot as a war cripple, are not: easily aroused for the overcoming of his infirmities. It is important to prevent this more or less subconscious psychic adjustment to the supposedly inevitable, and thereby to keep the man’s will power at a high standard. There is not much more to be done with a broken spirit than with a broken back. We must remember that it is a human trait, fostered by generations who have extended pity to the maimed and crippled, to exaggerate rather than to make light of a loss of bodily health and strength. This attitude of weak sentimentality toward invalids of all kinds requires changing, in their own best interest. While it is never a disgrace to be sick or disabled, it is one to remain unnecessarily a burden to the community. In our enlightened days, much can be and is being done to save our gallant soldiers from the gloomy fate of crippled war veterans. , Excellent suggestions along this line have recently been offered by Dr. M. Stassen, in charge of the work of reeducating the Belgian mutilés at Port Villez, in France, who emphasizes and in a personal letter repeats that this assistance ought to begin in the hospitals at the front immediately after the infliction of the wound or the per- formance of an operation, without waiting for anatomical repair and consolidation of broken bones. It is during this period of en- 164 I, FUNCTIONAL REEDUCATION. forced inactivity thut the prospects of a final cure, with functional efficiency, are often seriously damaged or even entirely lost by the patient’s acceptance of what he deems a hopeless struggle against overwhelming odds. ° Of special bearing on the ultimate outcome is the loss of muscular tonus in the fleshy. coverings of the affected limb, in consequence of its functional disuse. The only remedy against this insidious deterioration, and incidentally a permanent loss in working capacity, is functional reeducation through the me- dium of work. ; .For the welfare of the disabled soldiers, this functional reeduca- tion must not be postponed until anatomical consolidation has actu- ally occurred. The educational treatment should begin directly after the traumatism or the curative intervention. Early mobiliza- tion is often of well-nigh the same importance in the treatment of war wounds as is wound sterilization. We improve the nutrition of the damaged limb by determining a healthy flow of blood to the part, and thereby activate the process of. repair. The correct application of work as a therapeutic measure for dis- abled groups of muscles naturally presupposes familiarity on the part of the physician in charge with the corresponding laboratory methods and mechanical manoeuvers. The method of immediate active mobilization finds a promising field in a great variety of cases, such as amputations, fractures, in- juries of joints or soft parts, etc., briefly, in the majority of all the ordinary wounds of war. Soldiers with injuries of the nerves or blood vessels, of the spinal cord and cranium, no matter how seriously disabled, will, with few exceptions, be likewise benefited by prompt functional utilization of all those muscular groups which have escaped destruction. Postoperative treatment should be carried out under the collabora- tion of the operating surgeon, the bactericlogist, the mechano-thera- peutist, and the specialist in prosthetic appliances. A very responsi- ble part of the treatment devolves upon the physician charged with persuading the patient that his injured limb can and should be used from the first hours following the traumatism or operation. The patient must be taught the performance of the active movements needed to maintain the teamwork of the muscles and tendons as well as to preserve the suppleness of the articulations. Willing and in- telligent compliance with these instructions is equivalent to the best possible functional utilization and reeducation of the limb. Simple and easily renewable prostheses should be provided and fitted within the first few days, thereby facilitating the functional activity to the highest possible degree. Exercise rooms and laboratories of this type should be under the direction of experienced physicians capable of prescribing the work- ‘ZOLA HOd ‘sajddjso 4BM JOj jOOYds eUO!}eONpae UBIZ[9g ‘“Suljesoovap eulyD 164-1 ZONA Hog 'sajddio 4BM JO} [OOYDS |BUOeoNpads UBIB\Og ‘spe oIjsBid ul Buluyes) 164—2 "ZAIIIA HOd ‘sajddiio 4eM 40} JOOYdS |Bud|}BonNp|ss uBIZ}9g ‘doys Bulyeu-ssouiey 3 164 ‘ZOINA WOd ‘sajdd|4o eM 10} JOOUDS |BucI}eonpees uvIZ|eg doys Sulusn}-poomM e 164-4 “ZOIIIA WOd ‘sajddiso sem 40} JOOYOS JBUO!WBVONp|al UBIS|9g ‘doys Sululd 164-5 ‘ZOIILA HOd salddisio sem JO} JOOYUDS JeuOl}eONpees uBIBjag ‘dous Buljuldd ‘Z9IIIA Od ‘Salddi49 Jem 4OJ jOOYDS |BUOI}eONpsed_uUBIZ|9g ‘doys Asjua died 164-7 ; 00 “ZOINA HOd ‘salddiso sem 305 looyos leuoneonpee4 ueisieg Bulusin} POoM 164-8 “ZINA }40d ‘sajddiio Jem JOJ OOYOS JeUud!}eONpaed uRIZ}eg “doys eulyory) 164-9 ‘ZINA HOd ‘sajddiio 4eM Joy Jooyos |euopeonpaastuelsleg ‘Joys Bujpuiqyuoog 164-10 Belgian reeducational school for war cripples, Port Villez. Linotyping. 164-11 Agricultural school, Juvisy. Agricultural school, Juvisy. Group of men who were farmers before the war. They “are unfit for farm labor because of paralysis of the hand. 164-12 Reeducation for light work. I. FUNCTIONAL REEDUCATION. 165 jing movements adapted to the different groups of disabled soldiers. For example, there exists: a special series of selected and graded working exercises for those who have lost an upper extremity; an- other series is destined for resections of the elbow or shoulder, etc. Special walking and marching exercises, on peg legs, have been «devised for cases of amputation of the lower extremity. This physio-therapeutic method of treatment is distinct from the workshops which have been established for the vocational reeducation * of the wounded, either to refit them for their occupation before the war, or to train them for other work, according to their personal in- clinations or the exigencies of their physical condition. The mechani- cal movements under present consideration have no vocational but simply a therapeutic bearing. The selection of the curative exercises . is governed exclusively by the lesion itself and aims at insuring the best possible working capacity of the man on his return to civil life. The beneficial influence exerted by immediate active mobilization and functional utilization on the course of the injuries themselves is such as to reduce to mere accessories the ordinary mechano, electro, or hydro therapeutic methods of treatment. Functional reeducation by work hastens consolidation in severe fractures, and the shattered limb accordingly reaches its permanent condition earlier than otherwise, with the result that the patients can be equipped proportionately sooner with their definite prosthetic ap- paratus, and can then be evacuated from the hospital to the institu- tions for vocational reeducation. Here it will prove advantageous and even indispensable, at least for certain groups of cases, to con- tinue the functional reeducation started in the hospital. In the Port Villez Military Institute, under the direction of Dr. Stassen, courses of general gymnastic exercises and reeducation in walking have been established for trephined patients with hemi- plegia or paraplegia, as well as for cases of spinal cord lesion, etc. Patients with sutured nerves, which heal very slowly, are also given the benefit of routine reeducation exercises under medical supervision. For the maintenance of the results achieved by functional reeduca- tion Dr. Stassen has arranged a course in general gymnastics for men whose lower extremities have been amputated. Under the direction of an Army officer rapid marches are frequently made with the arti- ficial limbs. Men whose upper extremities are paralyzed or have been amputated likewise take a course in general gymnastics. An- other course, for the utilization of artificial so-called “automatic arms,” under the direction of amputated men who are experts in the use of their prosthesis, is now under contemplation. For hygienic reasons, courses in physical reeducation are soon to be extended to mutilated men following sedentary occupations, such as shoe and harness makers. 166 Il. VOCATIONAL REEDUCATION. An attractive adjunct to this system of physical reeducation con- sists in a large hall and open grounds for the enjoyment of games, outdoor sports, and similar healthful activities. II. VOCATIONAL REEDUCATION. In repairing the ravages of the war probably no measure will make a stronger appeal to the sympathies of the American people than this one of vocational reeducation. If by reason of injuries received in the service of his country a man is debarred from return- ing to his former occupation, he must be given every opportunity to learn some other trade or profession which will enable him to become at least self-supporting.. The welfare of the Nation no less than the welfare of the individual demands it. While the general public in this country is not yet fully awake to the need of taking energetic steps to prepare to meet the require- ments in this field, small beginnings are being made in various centers, and the periodicals of the country are giving considerable space to the question of what must be done. The old feeling that these unfortunates should be hidden away in obscure corners has given place to the belief that by facing the question squarely and inviting public discussion and cooperation much can be done toward bettering their condition and returning them to useful occupations. Much propaganda work is needed to enlighten those at home as well as those in the field as to what has been accomplished by the other warring nations, and by means of moving pictures and other publicity agents the interest of the people should be stimulated, in order to eradicate the present tendency to regard thos. suffering from loss of limb as permanently out of the ranks of labor. To this end the Red Cross has epitomized for us in four cinema reels the work that is being done in restoring to economic independence the disabled, and these reels are herewith presented to the Navy Medical Sichoot. The French Government has found it advisable to institute a simi- lar campaign of education in order that not only the general public but the mutilés themselves may learn of the work that, i is being Hone in this field. At the cinema a few pictures are “sandwiched in,” and the official army photographers have prepared many photographs of mutilés actually at work. In Europe almost from the beginning of the war the importance’ of reeducation has been recognized. Two interallied conferences have been held to consider the “Aftercare of disabled men,” the last of which I was privileged to attend, in May, 1918, when delegates from Belgium, France, Great Britain, Italy, Portugal, Serbia, Siam, Grand Palais, Paris. Tinsmith workshop at the Grand Palais. 166-1 Shoemakers’ workshop at the Grand Palais. Carpenters’ workshop at the Grand Palais. 166—2 “The Boarding School,’’ 28 Quai Debilly, Paris. Front of institute on Quai Debilly, Paris, 166--3 Bookbinders' shop, Quai Debilly. French course, Quai Debilly. 166-4 Crippled Serbians preparing vegetable garden. Ecole Professionnelle des Mutilés, Tourvielle, Lyon. Fur industry workshop. This is an unique industry as applied to retraining of war cripples. 166-5 Ecole Professionnelle des Mutilés, Tourvielle, Lyon. Mutilé wearing mechanical-arm apparatus and carving wooden shoes. 166-6, - re II. VOCATIONAL REEDUCATION. 167 United States, and the British overseas dormminions met and discussed the work being done in their several countries. A monthly ‘magazine, the Revue Interalliée, is being published, devoted to the study of questions relating to war cripples, and the American Red Cross, always alert to encourage and carry on any enterprise which will be of benefit. to mankind, has organized in France a bureau for reeducation of mutilés, under the charge of Miss Grace Harper, ‘and is aiding and supplementing the work of the French. The Union des Colonies Etrangéres, largely composed of Americans, has also taken an active part in the development of these measures, and hundreds of centers have been established where reeducation is being carried on. Through the foresight and vision of M. Edouard Herriot, mayor of Lyons, France, was the first country to recognize ‘officially the wisdom and necessity of training its mutilés to become self-support- ing. fess or Q,more eur > : fi t N wT Echelle yxztonae oe i % less el sports Bye ie 6 + ‘\ x, ra) + 7M ek eft Oy FE CeO Qe] BLE > eS CK BTR $ +: YN xyS 4} Rey 3 + Ye SS Oe £f5T we OO” * YN Ny we ay ct Aye ft + ON . KcBSe x7 e/ ag, : ? a * a oer RY ® oa + * NOON N we wy gs tus ? Xe Ss = api, OA Rete ON a Bie seg ¢ rapidemen{ fgets Ve 5 : SONG recupérables /’ # Pi Be XN 3 ea / x hot A 1B Rloniag.eus at *Hopilal de base chicurgicale 10l\-£< ee ef malades ; 3o00 A Sooo Iifs Chalons formation re ak des Efapes 10 AOU 1917 ee de / it de base) Sooo lifs 4.Gossef ef & Mercier Surgical sanitary formations, 216 RECOMMENDATIONS. Throughout this report there will be found many suggestions from the experiences of our allies which might well form the basis for a long list of recommendations. For example, the adoption of certain methods of treatment, the testing of others, and the many questions relating to the establishment of special hospitals, convalescent camps, and centers for reeducation. It is not the purpose, however, at this time to go into such detail, but the following suggestions seem to re- quire early consideration: 1. More system is urgently needed in. the sending home of the. sick and wounded. Each transport should take only such numbers of surgical, insane, tuberculous, and other cases as it is equipped to handle. Before embarkation, the patients should be sorted by a medical officer having full knowledge of their condition and requirements and of the accommodations on the various trans- ports. > Transports carrying serious surgical cases should have proper operating room facilities, X-ray apparatus, assorted sizes of Thomas splints, and Carrel- Dakin equipment, as well as hospital corpsmen with special training. The sur- geons in charge should be thoroughly familiar with the various’ methods of treatment now in vogue in order that they may intelligently continue such treatment as the case has been receiving, or, if occasion requires, change it to the advantage of the patient. 3. As gas and oxygen, with or without ether, is becoming largely the anes- thetic preferred in war surgery, our base hospitals and ships caring for many surgical cases should be equipped for its use. The apparatus recently devised by the American Red Cross is simple and cheap and has been ordered in large quantities for the Army, and,as pointed out by Gwathmey, is easily adaptable for ships. 4, On all large transports and at the Navy base hospitals there should be provided for the surgical personnel the following books: (a) Military Medical Manuals (21 vols.); Sir Alfred Keogh, G. C. B., L. L. D., F. R. C. S., editor. (bd) Report on the Medico-Military Aspects of the European War, by Surgeon A. M. Fauntleroy, United States Navy. (c) Manual of Military Urology, published for the American Expeditionary Forces by the American Red Cross. (d) The Medical Bulletin, published monthly by the American Red Cross Society in France. . (e) Certain new books, published or to be published by leading surgeons en- gaged in war surgery, such as Blake’s book on Fractures, Willems on Septic Joints, Souttar on Nerve Suture, Robert Jones on Orthopedic Surgery, Lock- wood on Surgery of the Forward Area, Sinclair on Fractures, and Williams on War Neurology, etc. 93696—19—15 217 218 RECOMMENDATIONS. 5. On such transports there should also be provided for reference use by our hospital corpsmen certain of the books now used for instruction in the best training schools for nurses. 6. Provision should be made at the ports of embarkation for the thorough elimination of lice from the persons and clothing of troops before they are taken on board. 7. At all naval training stations and base hospitals there should be installed the Barron ladder, or such modification of it as seems advisable, for the pre- vention and cure of flat foot. 8 The beneficial effect of the early use of provisional apparatus in ampu- tated cases should be recognized and adequately provided for in all Navy base hospitals where such cases are under care. 9. More Navy surgeons and dentists might well be sent abroad to the special hospitals and centers where opportunity is offered for practical experience in the most recent developments in military orthopedics, plastic and oral surgery, nerve suture, the making and fitting of prosthetic apparatus, ete. 10. The value of blood transfusion in chronic sepsis, and the donor law in relation to skin grafting and transplanting of other tissues should be deter- mined as promptly as possible, 11. Rules for massage, such as those in use at the Alder-Hey Military Ortho- pedic Hospital, should be printed and distributed among those responsible for the giving of such treatment. 12. By way of neutralizing the insidious effects of enemy propaganda, there might well be inaugurated for the Navy personnel a series of entertainments in the form of moving pictures, short talks, etc., with a view to familiarizing the men with the objects of the war and what is being done at home and abroad, and especially acquainting them with what is being done toward the physical reconstruction and vocational. reeducation of those badly injured. The spread of such information will be beneficial not only to the enlisted men but to all with whom they come in contact. TECHNICAL INSTRUCTIONS IN VIEW OF THE IMPENDING MILITARY ACTIVITIES. This instruction comprises the conclusions expressed by the differ- ent chiefs of the technical service of the Sixth Army. Early surgical attention is the most powerful means to guard the wounded against all infectious complications. Uniformity and con- tinuity of treatment are the important factors of success. They are secured through the technical connection between the surgeons of the different stages of the sanitary formations. The surgical service of the Sixth Army has endeavored to put these requirements into prac- tice, as shown in the following: ROLE OF EACH SANITARY FORMATION. 1. REGIMENTAL AID POSTS. The application of simple dressings, immobilization of fractures, control of hemorrhages, and as rapid evacuation as possible constitute their principal activity. Wounds are to be dressed by means of ordi- nary gauze, the surface application of Vincent’s powder serving espe- cially in those cases whose evacuation is delayed. Hemorrhage is treated by simple packing of the wound, without constriction of the limb. The tourniquet is to be reserved for excep- tional cases, and a special label must indicate its presence, the neces- sity of immediate evacuation, and a priority examination on arrival at the grouped ambulances. Fractures are carefully immobilized by means of one of the appa- ratuses in the use of which each regimental surgeon has been in- structed. (On the arrival of the wounded in an ulterior formation, the apparatus will be exchanged, one apparatus for another.) For fractures of the thigh, it must be kept in mind that in order to be efficacious, every apparatus must reach from the axillary re- gion as far as the malleoli. Antitetanic injections should be administered as far as practicable. Symptoms of shock are treated with tonic hot beverages, warming of the entire body, and injections of camphorated oil repeated every three hours. Soldiers who have been “ gassed ” should be undressed, washed, and provided with a change of clothing. . 219 220 TECHNICAL INSTRUCTION ON EVE OF OFFENSIVE. Evacuation—The very severely wounded, when the diagnosis is positive and the general condition sufficient to tolerate transportation, whose treatment is extremely urgent, must be at once forwarded, di- rectly and without any further sorting, to the following formations: Fourteenth Corps, Hépital de Soissons. Twenty-first Corps, H. O. E. de Vasseny. Eleventh Corps, H. O. E. de Vasseny. Thirty-ninth Corps, H. O. E. de Mont-Notre-Dame. Severe fractures of the diaphyses are to be directly forwarded, with the following attached label: For the Fourteenth Corps, to the fracture center of Vierzy. For the Twenty-first, Eleventh, and Thirty-ninth Corps, to the fracture centers of Mont-Notre-Dame or to the center of Chateau- Thierry. All other cases of wounds or intoxications are to be directed to the sorting posts constituted by the grouped ambulances: For the Fourteenth Corps, For the Twenty-first Corps, Sermoise, For the Eleventh Corps, Courcelles, For the Thirty-ninth Corps, Cerseuil, GROUPED AMBULANCES, SORTING POSTS. The part played by these is of the utmost importance. Antitetanic injections are here administered when these have been omitted at the aid posts. 1. Sorting —This must be left in charge of experienced surgeons. All dressings are to be removed.. The diagnosis will be based upon direct examination of the lesion. After readjustment of dressings and apparatus, the wounded will be directed to a new previously designated sanitary formation. All tourniquets should be removed when the origin of the hemor- rhage can easily be seen. Hemostatic forceps are applied and left in place. When the hemorrhage is deep, the tourniquet is retightened and the patient is detained in the hospitalization of the same grouped ambulances, with a special recommendation to the surgeon in charge. All nontransportable cases are detained in the hospitalization. All gassed soldiers are likewise to be detained and treated, if not already treated in the aid post at the front. These nontransportable wounded are, for the most part, cases of severe shock, with or without hemorrhage; wounds of the skull and brain, with escape of cerebral substance, and a bad general condi- tion; extensive shattering of limbs requiring immediate amputa- tion; penetrating wounds of the abdomen, wounds of the thorax with persistent hemorrhage or threatened asphyxia. TECHNICAL INSTRUCTION ON EVE OF OFFENSIVE. 221 Cases of very minor injuries, and the slightly wounded, are like- wise to be detained when they can not be accommodated in the evacu- ation hospitals. 2. To be evacuated—l. The disabled, for the Fourteenth and Twenty-first Corps, to La Ferte Milon. 2. Urinary cases, to the center of Busancy. 3. Fractures, for the Fourteenth Corps, to the hospital of Vierzy; for the Twenty-first, Eleventh, and Thirty-ninth Corps, to the Frac- ture center of Mont-Notre-Dame or that of Chateau-Thierry. 4, Lesions of the face, jaws, and orbit, to the H. O. E. of Vasseny. All other wounded are to be directed to the following centers: Fourteenth Corps, H. O. E. of Soissons, with overflow to Busaney and Vierzy. Twenty-first Corps, H. O: E. of Vasseny. Eleventh and Thirty-ninth Corps, H. O. E. of Mont-Notre- Dame or of Saint-Gilles. All apparatus removed in the grouped ambulances is to be returned to the corresponding aid post. ROLE OF HOSPITALIZATION OF THE GROUPED AMBULANCES. 1. Service of nontransportable cases.—It consists in the exclusive reception of nontransportable wounded, and of soldiers with very trifling injuries, only in case of overburdening of the evacuation hospitals. These wounded are to remain in these formations no longer than the strictly necessary time to ascertain the harmlessness of their transportation before or after operation. Any delay in their evacua- tion is most prejudicial for these wounded. An appeal is made to the ‘ conscience of the surgeons in charge, who may always follow the re- sults of their treatment in the sanitary formation to which they have evacuated their patients after operation: To detain a wounded sol- dier outside of these special conditions is to expose him to compli- cations. These wounded, having become transportable, will be evacuated to— Fourteenth Corps,-H. O. E. of Soissons. Twenty-first Corps, H. O. E. of Vasseny. Eleventh and Thirty-ninth Corps, H. O. E. of Mont-Notre-Dame, and, if necessary, H. O. E. of Saint-Gilles. 2. Slightly wounded.—Foreign bodies which can easily be ex- tracted without great tissue destruction are to be removed. Wounds are to be freely opened, excised, dressed, and bandaged, directing the patients for suture to the surgical centers. 222 TECHNICAL INSTRUCTION ON EVE OF OFFENSIVE. ROLE OF THE H. 0. E. OF SOISSONS, THE BUSANCY GROUP, AND THE H. O. E. OF VASSENY, MONT-NOTRE-DAME, SAINT-GILLES, AND VIERZY. The selection and destination of the hospital to be allotted to the wounded in these centers will be determined and specified by the chief physician of each of these hospitals. ‘The management of the wounded will be prescribed by each of the surgeons at the head of the service. Technical questions will be indicated, when necessary, by the heads of service in the centers, in accordance with the operating surgeons. The evacuation of the wounded from these surgical cénters, in order to establish a connection with the formations at the rear, will be carried out in the following directions: The fractures of the Vierzy center and those of the H. O. E of Soissons are to be directed as soon as their condition permits, namely, when the cicatrization of the wound allows it, to the fracture center of Compiégne, by boat or rail. Those of the H. O. E. of Vasseny and of Mont-Notre-Dame, to the fracture centers of Chateau-Thierry, and, when this does not suf- fice, to Paris. Soldiers with wounds of the face, jaws, orbit, and eyes will be -directed to the center of Paris as soon as their transportation involves no danger. Wounds of the soft parts, after incision and exposure, for suturing, or immediately after their cicatrization, will be directed to In case of overcrowding of the wounded, evacuations of all kinds will be carried out by special trains to Paris. REPORT OF THE SURGICAL TECHNICAL ADVISORY é COUNCIL. Composed of Medical Inspector General Frevrire, Profs. HARTMANN and DELBET. The surgical technical advisory council was consulted as to the best place for the evacuation hospitals. The absence of its president hav- ing caused a certain delay in the meeting of the technical advisory council, before the question could be taken up, a note was submitted entitled “ General Indications to Serve for the Organization of the Sanitary Service According to the Regulations.” As the place of the evacuation hospitals is closely related to the general organization of the sanitary service, it appeared advisable to study this note asa whole. The evacuation hospitals, as originally planned, were based on the imaginary inviolability of the front. This place has been fixed at a distance of 18 to 20 kilometers from the fighting lines. This suffices to show that they are impracticable, as the front may actually vary for a more considerable distance in 24 hours. We have unfortunately learned the cost of fixedness of the evacuation hospitals located in this zone. The altered character of the war demands a change in the organiza- tion of the sanitary service in the zone of the armies. The note sub- mitted to us by the surgical technical advisory council aims at the establishment of a new régime and seems to be well conceived in its general outlines. The points which it seems to us might be modified are indicated in the following: , 1. Aid posts.—This question is not considered in the note. We wish to suggest in this tonnection an organization already proposed by us, adopted in certain armies, and worthy of general introduction. For certain wounded, the diagnosis is so obvious as to render undesirable their passage through the sorting station, this passage being incon- venient for the patient, whose treatment is thus retarded, and incon- venient for the center, which is always overworked during a period of offensive. These wounded should be provided with special labels insuring their direct transportation, without interruption, to the place where they are efficiently taken care of. They belong in three groups, each of which should bear a special label, easily recognizable by its shape or color. (a) One group comprises wounds of the abdomen, open thorax (perforating wounds of the chest), vascular wounds treated with a tourniquet. Soldiers with such lesions must be sent directly from the aid post to the advanced dressing station. ‘ 223 224 REPORT OF TECHNICAL ADVISORY COUNCIL. (b) A second group comprises gross fractures and also gross con- tusions of the soft parts (calf, thigh, buttock, axilla, shoulder), which expose particularly to gas gangrene. The wounded of this group must be taken directly to the primary evacuation hospitals. ‘(c) The third group comprises the fractures of the skull. Ex- perience having shown that it is better to transport these patients be- fore than after the operation, we hold that they should be taken directly to the secondary evacuation hospitals. 2. Army formations —(a) These formations should be very mov- able. It seems, therefore, necessary to specify those which should be installed under tents. (b) We hold that these formations should be divided into two sec- tions: One sorting section and one surgical section, properly speak- ing. These two sections must be adjacent but independent. The note under consideration indicates that these formations are to treat on the spot the grave nontransportable cases and those which are in need of emergency measures. There is nothing to add about the nontransportable cases, but “those in need of emergency meas- ures” leaves too much room for different interpretations. A few explanatory words should be added without definite restrictions. It should be specified that abdominal wounds, perforating wounds of the thorax, vascular wounds associated with hemorrhage arrested by a tourniquet, are to be cared for in these formations. In the organi- zation as proposed by us those wounded would be directly taken there. (The submitted note anticipated for these formations an operating staff able to perform this major surgery.) 3. Primary evacuation hospitals.—We believe that these hospitals which are to be placed at the rail heads should likewise be installed under tents, as already requested by the technical advisory council ina preceding report (by Hartmann). In our opinion these hospitals should take care of the gross frac- tures and gross contusions of soft parts, which will be sent to them directly from the aid post. The note anticipates these evacuation hospitals to be equipped with a service capable of adjusting provisional maxillary-facial prostheses, an ophthalmological service, etc. Such equipments ap- pear to us out of place in these hospitals. Patients with wounds of the face are among the most easily transported. A delay of a few hours is of no importance for them. They should be treated in the secondary evacuation hospitals. One of the duties assigned by the note to the secondary evacuation hospitals is that of directing the lightly wounded, the sick who will promptly recover, and the disabled to special dean iy destinations. Leaving aside the sick and disabled—emphasizing, however, that REPORT OF TECHNICAL ADVISORY COUNCIL. 225 the disabled must not be confused with the slightly wounded—we wish to call special attention to the latter. The gravely wounded, whose lives are directly threatened, hold a predominant place in our preparations. They make a more pro- found appeal to our sympathy and they gratify our surgical pride. From the military viewpoint, however, it is evident that the slightly and moderately wounded are entitled to the same care and must be handled by skilled surgeons in well-organized formations. The serious question of man power is far more concerned with the slightly wounded than with the seriously wounded. In 1915 we adopted Hartmann’s formula that there are no slightly wounded; meaning that at the time of distant evacuations many slightly wounded died of gas gangrene or acute septicemia. The formula is now resumed in a modified sense. We mean to say that wounded soldiers with not intrinsically very severe lesions enjoy at least as much as others the great surgical progress achieved in the course of this war in the form of resection followed by suture. Under insufficient care these wounded who represent the great’ majority of war casualties require weeks and often months to get well; they leave the hospital on convalescent leave; they regain their fitness very slowly. Some, entirely too many, retain fistulas, intra- muscular fibrous nodules, adherent cicatrices, which induce func- tional disturbances, and they never again become: fighters. Prop- erly managed, with trimming of the wound and primary suture, they leave the hospital at the end of a dozen days with a leave (per- mission) of 10 days. In three weeks they are well. All those who have visited a large number of sanitary formations know that the slightly wounded, when insufficiently treated at first, often require more time to recover than moderately or even certain severely wounded who are well taken care of. Undoubtedly, at times of great inflow of wounded, surgeons are obliged to devote their efforts first to those whose lives depend upon their interventions. But it can not be overemphasized to the sani- tary service that the slightly and moderately wounded be cared for in good installations and by competent surgeons. There is neither necessity of nor advantage in having them treated in formations near the primary evacuation hospitals; no necessity because they can tolerate a slightly longer journey, and no advantage because one can extend to any hospital the right to discharge the patient on a 10 days’ leave. — 4, Secondary evacuation hospitals—In these formations the ma- jority of wounded will be operated upon, and it is on this subject that we have been specially consulted. As to the importance attached to them we entirely agree with the note. It properly emphasizes the disadvantages of scattering the 226 REPORT OF TECHNICAL ADVISORY COUNCIL. wounded and cleverly expresses the situation of surgical staffs in small formations, where they are alternately overworked and in a state of inactivity. Strong organizations with a large material are accordingly needed. They should be supplied by a special railway with branches per- mitting the yarding of several trains, and platforms facilitating the unloading of the wounded. As to the distance at which they should be placed, this question, specially addressed to us, still presupposes a certain stabilization of the front. This point does not fall within our domain. Moreover, as the wounded may be very numerous, as the neighboring regions have no organization permitting them to be properly cared for, it is imperative to create large surgical forma- tions, and the position of these must necessarily be governed by the ‘point where the wounds are inflicted, namely, starting at the front. The note counts by kilometers (50 to 200). Time is not directly related to distance, for many other factors intervene. Not the kilo- meters, but the hours are of importance, meaning the duration of the transportation. It therefore seems preferable to count by hours. Two necessities arise, which are to a certain degree contradictory— that of protecting these large formations against the ordinary fluctu- ations of active warfare, and that of managing the wounded as soon as possible. One demands removal, and the other approximation, of the surgical centers. Our personal experiences in the course of the last offensives permit to conciliate proper care of the wounded with the safety of the sec- ondary evacuation hospitals. The period during which a medium-sized wound remains capable of being sutured is more extensive than was assumed to be the case. While suture was considered very risky after the eighth or tenth hour, practically all the wounded were systematically sutured who arrived unoperated in our Paris services. These wounds dated back 24, 86, 48 hours. Such remarks can at present be passed only with extreme caution. It always remains desirable for the wounded to be operated upon as promptly as possible, but it is certain that a competent surgeon should not omit suture for the sole reason that the wound dates back 24 to 36 hours. Thus there actually exists a margin which permits placing the great surgical stations in an at least relative zone of security, for assuredly no organization can be established which is equally satis- factory at a time of great disaster or great victory. Except the wounded of various groups, which have already been specified, as to be operated upon in the army formations (advanced dressing stations) or in the primary evacuation hospitals, we believe that nonoperated patients can tolerate a railroad transportation last- REPORT OF TECHNICAL ADVISORY COUNCIL. 227 ing at most 10 hours from the point of entraining. Counting that this point will be reached in an average time of six to eight hours, they will be operated upon within 24 hours, namely, during the period in which suture is possible in properly managed cases. The first thing to be done in order to decide the location of the secondary evacuation hospitals is to ask the G. Q. G. to indicate the limits of the zone whose security is believed to be sufficient. The second point is to request the IV Bureau to specify the points of this zone where the, roads can be made to converge, so that the trains coming from the most advanced stations can arrive here in less than 10 hours. FIXATION OF THE BASE OF HOSPITALIZATION AND THE SURGICAL MEASURES NEEDED FOR AN AT- TACKING ARMY CORPS IN AN OFFENSIVE. The experience of the different offensives has shown the neces- sity for organizing a solid base of hospitalization well in advance for each of the working C. A., to receive the wounded, and a sufficiently complete surgical service to operate upon them with an average delay of 24 (exceptionally 48) hours. The teachings of the present war permit to fix approximately the conditions which this base must meet for a C. A. of attack like the first C. A. C. The essential points to determine are as follows: The number of beds and the surgical means. These points rest on three essential factors: 1. The production or incidence of the wounded. 2. Their debit and their hospitalization. 3. Their surgical liquidation. 1. PRODUCTION OF THH WOUNDED. Calculations concerning the production of the wounded are based on the losses sustained by the first C. A. C. in the course of the three great offensives in which it participated: Battle of Champagne, September—October, 1915. Battle of the Somme, July-August, 1916. Battle of Soissonnais, April-May, 1917. GHRONOLOGIOAL DAILY AVERAGE OF WOUNDED PER DIVISION IN AN ATTACKING ARMY CORPS. The average number of wounded must be established in chrono- logical order for the total of the divisions of the army corps (aligned or in reserve) during the entire duration of the procedures. This is indispensable in order to arrive at an average calculation, for in offensive procedures, the divisions are almost invariably grouped in army corps and liable to enter in line at a given moment. A calculation based solely on the divisions having sustained the greatest losses would no longer correspond to the medium figure of the chronological series, since all the divisions are never simultane- ously engaged, and on the other hand the maximal losses are essen- 229 230 BASE HOSPITALIZATION AND SURGICAL MEASURES, tially variable according to the difficulties of the terrain and the particular fluctuations of the fight. The maximal losses in wounded of the divisions of the first C. A. C. correspond to the figures given below: Champagne (September, 1915) : September 25 (3 divisions). 309 1,200 0 tones 1,434 478 September 26 (3 divisions). 543 891 6500 JDivisions 1,509 503 Somme (July, 1916) : July 1 (4 divisions) ___-__----- 589 789 220 0 1,598 899 July 10 (4 divisions) __-_------ 589 504 951 293 1,748 487 Soissonnais (April-May, 1917) : April 16 (3 divisions) _-_-------__ 546 386 220 387 976 811 May 5 (3 divisions) _--_-__------__ 546 589 951 387 976 325 Once only, on September 25, 1915, the average surpassed 500 (508) ; next day it was almost the same (478). The other averages are around 400. Table A gives the detailed calculation in the divisions, and’ the graphic Al permits following the oscillations of the daily average of wounded in the divisions as a whole, the average man power per division being 12,000 soldiers. The curves AQ and A10 show the detailed variations for each division. The study of these Bgures and graphics leads to the following con- clusions: . 1. The maximal losses always occurred on the days “J” and “ J-1,” then a diminution takes place with some sudden elevations due to counterattacks, and finally, on a variable day (“J-5” to “ J-20”), there appears another ascent, often as important as the maximum at the beginning, and followed by the lowering which terminates in stabilization. “J,” general average of losses per division 884 “ J-1,” general average of losses per division 302 (Following days, fall with oscillations.) Day “ J-x,” second ascent. 403 (Following days, fall with oscillations.) 2. The maximal losses always taking place at “J” and “J-,” these days must serve as the basis for determining the liquidation: Offensive of Champagne ; 503 478 981 Offensive of the Somme. 399 338 737 Offensive of Soissonnais, first attack_-------------___-____ 310 170 480 Offensive of Soissonnais, second attack.__.__________________ 325 222 547 Average 2, 745 685 AVERAGE OF WOUNDED ON pays “J” anp “g—1 IN ARMY CORPS AS A WHOLE. In an army corps the divisions furnish the majority of the losses, but it is also imperative to consider the E. N. E., whose importance BASE ‘HOSPITALIZATION AND SURGICAL MEASURES. 231 _steadily increases with the development of heavy artillery and with the necessity. of renewing up to the first line the actively engaged troops (territorial elements). . These losses. are especially marked in offensives followed by oc- cupation of new nonorganized positions, as occurred on the Somme in July-August, 1916. The graphic B gives the figures, which can be estimated at an average of 30 per day. In an Army corps of 4 divisions the number of wounded for the days “J” and “J-1” must accordingly be estimated as: (6854) +60=2,800. MAXIMUM OF ATTACKING DIVISIONS ON DAY “3,” Besides the averages of wounded established in chronological order on the total of the divisions of an army corps (divisions in line and, in reserve) it is of great interest to learn the maximum of wounded calculated exclusively for the attacking divisions. These maxima (Table C) are significant only on the days “J” and “ J-1,” for the day of ascent “ J-X” is too variable for the av- erage, dating from “ J~X,” to possess value as regards the estimation of the yield in wounded. The maxima of the days “ J” and “ J-1” have been as follows: : Battle of Champagne: Second D. I. C 809 543 Third D, T. C 1, 200 891 Thirty-second D. I 500 543 Battle of the Somme: Second D. I. C._-- 589 471 Third D. I. C 789 626 Sixteenth D. D. I. C 220 = «249 D. M 215 446 Seventy-second D. I - 208 298 Battle of Soissonnais: Second D. I. C 546 351 Third D. I. C 386 159 Third D. I. C : 589 —- 806 D. P. : 387 359 The general average of the attacking divisions is thus seen to be 561 on day “J” and 506 on day “ J-1,” making 1,067 wounded for the two days “J” and “ J-1.” ‘This information is important for the provisions to be made when in the course of the procedures, a fresh division enters in line and prepares to attack. From this basis should be planned the required hospital accommodation and surgical facilities. 232 BASE HOSPITALIZATION AND SURGICAL MEASURES. II, SUPPLY OF WOUNDED. For the time being, the wounded are delivered in three stops: 1. Divisional aid posts (ambulance division). 2. Central sorting station of the army corps (gathering of am- bulances). 3. H. O. E. (evacuation hospitals). DIVISIONAL AID POSTS. The divisional aid posts, provided they are sufficiently spacious and their service is strictly regulated, have an extremely important réle in the first sorting of the cases. 1. Removal of disabled (lame) by T. M. for transportation to the depots. Removal of slightly wounded by T. M. for transportation to the ambulance for recuperable cases. 2. Immobilization on the spot for absolutely untransportable cases. 3. Evacuation of the other wounded in the order of severity toward the sorting center of the army corps (gathering of ambulances). Not mentioning the disabled, whose number is very variable, ac- cording to the conditions of flood nourishment, and weather (in- fluence of rain and cold), the divisional aid posts may be estimated to liquidate as follows: Twenty-three per cent of recuperable slightly Saude. 1.21 per cent of very seriously and absolutely nontransportable ‘wounded, equaling about one-fourth of the total of the wounded, so that the average of the two first days (J and J—1) drops from. 685 to 518. SORTING CENTER OF ARMY CORPS. The sorting center retains the nontransportable wounded, directs to the service for recuperables the slightly wounded who may have escaped the first-line divisional ambulances, and evacuates all the remainder to the H. O. E. Too much must not be expected from its quantitative yield, on ac- count of the group of patients which it retains and also because its surgical facilities will always be limited. _ Consequently, do not calculate from the number of beds but from the probabilities of operative material in the 24 hours. Under these conditions it must not be relied on to retain more than 120 wounded. All the remainder will go to the “H. O. E.,” making for the days “J” and “J—1,” 518, 120, and 393. Base of hospitalization—Summarizing, the hospitalization base of the army corps consists of the following: The beds of the sorting center ; the beds of the H. O. E, proportioned to the surgical resources. BA“E HOSPITALIZATION AND SURGICAL MEASURES. 233 As the outflow of wounded does not begin until day “J-2,” this base must correspond to the number of wounded in these two days, deducting the slightly wounded recuperable (23 per cent) and the absolutely nontransportable (1.21 per cent), averaging 513, But it is absolutely necessary to take into account the conditions of the debit and number of untransportable cases. . The debit, insignificant on day J-1, may be estimated: ' At 10 per cent on day J-2; at 20 and 30 per cent on the following ays. With special reference to the nontransportable, whose proportion increases every day, and may reach one-fourth of the beds on days J to J-4, and even one-third of the beds on days J-6 to J-9; a place for them is practically guaranteed by raising to 800 per division the required total of 518 places. Provisions for new attacks—In.case of an attack in the course of the procedures by a fresh division, it is advisable to refer to the figures of maximal losses sustained by a division which enters in line. These losses may amount to 561, 506, 1,067 for days J and J-1. Hence, evacuate so as to have the necessary room and collect the surgical means which are indispensable. SUMMARY. 1. A division yielding 685 wounded on days J and J-1: 25 per cent are removed by the first-line divisional ambulances; 513 are received in the sorting centers of the army corps and of the “H. O. E.” (beds and surgical facilities to be provided). 2. In consideration of the duration of the back flow of wounded (10 to 80 per cent daily) and the number of nontransportable cases (one-fourth to one-third from days J to J-9) the total number of beds must be raised from 518 to 800. 8. These calculations are made for one division, on the total of the divisions of an attacking army corps, including the divisions held in reserve. ‘ In case of the entrance in line of a new division it is necessary to tabulate above the maximum figure of losses of the divisions whick have actually attacked, the days J and J-1, namely, 561, 506, 1,067. Beds, surgical facilities, and debit must be accordingly pro- vided for. SURGICAL LIQUIDATION. The divisional aid posts liquidate: 23 per cent of recuperable slightly wounded, who are directed to a special formation (ambu- lance or H. O. E.); 1.21 per cent of absolutely untransportable 93696—19——_16 234 BASE HOSPITALIZATION AND SURGICAL MEASURES. cases, kept where they are, so that the total of days J and J-1, which amounts to 685 wounded per division, drops to 518, shared between the group of ambulances and the H. O. E. Of this number, the average of inevacuable cases which must. be kept: “hospitalized” is 25 per cent; the others can be evacuated after operation and rest, making— Inevacuable hospitalized ---- 128 Evacuable transients 385 LIQUIDATION OF INEVACUABLES. Of the 128 hospitalized cases, one-tenth are not operable; the others, amounting to 115, must be operated upon within 24 hours. The average yield of a very efficient surgical service A rarely exceeds one wounded per hour. As the activity must be continuous for several days, it is not possible to count more than 12 working hours per service, making 12 wounded daily; the 115 grave cases of days J and J-1 (two days) accordingly require, per division: 115 ~g :12=5 surgical services A. LIQUIDATION. OF EVACUABLES. The evacuable cases are partly recumbent and partly seated. The average duration of the operative interference is a little shorter in the recumbent than in the hospitalized, and the yield may be estimated as 15 instead of 12 per service. For the seated evacuables the yield is much more considerable and often exceeds 50; by reducing it to the figure 45, one obtains for the two groups of evacuables a daily average of: 15-+-45 ‘ =30 operated per service A or B. The 385 evacuables of days J and J-1 (two days) therefore will require, per division: 885 —:30=7 services A or B. 2 TOTAL LIQUIDATION, ’ For the 513 wounded, to be liquidated by one division, will be ‘required : 5 services A, for the inevacuables. 7 services A or B, for the evacuables. Total 12 services, of which at least 5 must be of the first class (service A). BASE HOSPITALIZATION AND SURGICAL MEASURES. 235 For an army corps of 4 divisions: 12x4=48 Sac with 20 serv- ices A. For an army operating with 5 army corps of 4 divisions each (20 divisions), the liquidation of all the wounded of days J and J-1, in the 24 hours following their arrival, will therefore require: 12X20=240, 100 of which to be A. For the total, each army corps will provide one service per divi- sion and one for E. N. E., making for an army corps of 4 divisions 5:services, and for an army with 5 army corps 25 services. Of the necessary 240 services, 215 would still remain to be furnished. In order to guard against disappointment, it is advisable to re- member and ponder on these figures. With the progressive spread of the offensives, these needs can only increase, and the surgical serv- ices at the disposal of the armies will be more and more swamped. It must be positively established that the H. O. E. will hospitalize only in the measure of its surgical facilities, and that its surgical output will be unable to meet the requirements of the inevacuable wounded. It is, therefore, useless to develop it disproportionately. . But on the contrary, it appears imperative to put it beforehand in close connection with a specially and very firmly organized sur- gical center, at no great distance, to which it will pass with the greatest system and with all desirable rapidity, the total of wounded which it can not handle surgically, meaning nearly all evacuable cases. This arrangement must be provided for beforehand: In the H. O. E.: Strengthening of the sorting and evacuating services. In the transportation service: Collection of necessary trains (for seated and recumbent) since day “J.” In the receiving service: Detraining of the wounded, hospitaliza- tion, mobilization of surgical facilities (ready to functionate on day “y ee In this manner it will be possible for all the wounded to be oper- ated upon at a delay never exceeding 48 hours since their departure from the aid post. It does not seem possible, at the present stage of the war, to devise another solution. (Signed) Lasnet, Medical Inspector and Army Physician. Jury 12, 1917. Fig. it, 236--1 Ea oe La S Yeon Ge enone ea LT LO AT oper ATES TN ww SSE =A ‘\ SS SSS SSS STAN < = eS SS ss A Ponte: ptt hs pow t Byler Aor PAYOR OTA fe Licata ameuats en g ae creed, Ce i Rp2F 01. Doone” enter Cla porter lex Lees cel ¢ Cog ey pe Z ¢ fancuttna2_. Infiltration with cocaine; 2, Crucial cicatrix; 3, incision for removal of most adherent purtion_of cicatrix. SS a SS SSsaus SSS Fo Wii iE Ba cdo! lew Peete 2 Mlocucerss. cle ctecothed fa dire ~ tin . Fig. 2.—1, Incision of pericranium; 2, method of detaching the dura mater, 236-2 CARTILAGINOUS CRANIOPLASTIES. In the course of a discussion on'trephining (see p. 72 of this re- port), reference has been made to Dr. Chutro’s promised account of his cartilaginous cranioplasties. This communication has just come: into my possession and in view of the interest and far- reaching i im-. portance of this procedure in war surgery, a full version in English is presented in the following text: CARTILAGINOUS CRANIOPLASTIES. Indications and Technic by Dr. P. CuurRo, Adjunct Professor of the Faculty of Buenos Aires, Chief Surgeon of the Military Hospital Buffon, Paris. ° A loss of substance of the cranial bones as such produces a series of subjective and objective phenomena known under the designation or trephinesyndrome. ” This syndrome is encountered pure and separately in cases of lesion of the bone, the dura mater and the superficial layers of the brain which have no differentiated function of any kind. It becomes superadded on the other hand to the clini- cal signs of the corresponding organic lesion, in the presence of de- struction of the cerebral substance of the motor or other zones which are the centers of various functions such as speech, vision, etc. The trephine-syndrome disappears almost entirely after a properly performed plastic operation on the skull, but the concomitant or- ganic lesions which may be present are in no way directly benefited by the operation. A case of hemiplegia will take its usual course, the patient obtaining merely the suppression of the irritable cortical phenomena through the cranioplastic operation. A patient with a lesion of the occipital lobe will invariably retain his ocular lesions. Cases of Jacksonian epilepsy sometimes improve after cranioplas- ties, or at least, the attacks will diminish in severity,. duration, and frequency, although total disappearance is uncommon. One of our patierts who suffered from monthly seizures, had his first post-operative attack 14 months after cranioplasty, and at- tributes it to brain fag caused by overwork as a bookkeeper in a bank. An officer whose attacks occurred several times daily found them becoming separated by progressively Iengthening intervals until they disappeared entirely. He had suffered, moreover, from monoplegia 237 238 CARTILAGINOUS CRANIOPLASTIES. of the left arm, which almost entirely subsided, leaving only a con- traction of the muscles of the fist. This officer was enabled to re- sume his position as an infantry instructor. In contradistinction from the above case, another officer with a frontal lesion, who suffered from severe and ‘frequent attacks of gen- eral epilepsy, was in no way benefited by the operation. As regards epileptic attacks, it must be stated that the numerous cases which have come under observation due to the war, have per- mitted neither the establishment of their etiology nor their patho- genesis. Some epileptic patients presented at the time of operation no compression or adhesion of the meninges; on the other hand, numerous patients with compression and extensive meningeal ad- hesions never presented the least sign of an epileptiform attack. Hence, a possible improvement, but no more can be promised to epileptics. Cranioplasty must accordingly aim at two ends: (1) Suppression of the faulty (but cosmetic) cicatrix; (2) suppression of the trephine- syndrome. After long experience with war surgery, we have reached the con- clusion that all faulty cicatrices of the body should be extirpated because they impede function, create abnormal adhesions, restrict the action of the muscles and joints, and constitute a permanent risk by their marked tendency to ulcerate and maintain foci of suppuration. The extirpation of cicatrices must be obligatory in the skull. In case of a simple lesion of the scalp which has undergone suppuration, the cicatrix is very likely to have become keloid and painful. When trephining has been done, the cicatrix is always adherent to the meninges and even to the brain. These adhesions cause constant traction and thereby continuous irritation of the meninges. On the other hand, superficial cicatrices are lined with a sometimes greatly thickened or actually keloid, sclerotic layer which when it comes in contact with the brain, instead of becoming outlined has a tendency to spread in the cerebral substance, thereby giving rise to a series of invariably grave secondary phenomena. Briefly, it is desirable to remove this keloid from the brain in order to put this organ at rest so that it may heal and limit its lesion. These irritable phenomena are part of the trephine-syndrome. The other signs which are frequently observed are as follows: (1) A sensation of emptiness in the trephined’ side. (2) A very unpleasant sensation sui-generis, felt by these patients when they are obliged to stoop or lower the head, manifesting itself in form of vertigoes and nauseas. The same phenomenon supervenes when they make some effort or on coughing. With the patient in a sitting position, a depression is seen at the site of lost substance; when he bends over, a hernia is seen to appear = Robot cde ta porke cle Substance. a Soler cur yo tenepotace Qa hurd - nicre Fig. 3—1, Border of loss of substance; 2, sclerotic tissue which replaces the dura mater; 3, method of dissecting out adherent cicatrix. 238-1 238-2 CARTILAGINOUS CRANIOPLASTIES. 239 in the same place. These continuous movements of the brain dis- turb the patient and when the loss of substance is considerable he is very apt to avoid all changes of position so-as not to experience this highly distressing sensation. (3) These patients can not tolerate external vibrations such as the rolling of a train, the shaking of an automobile, street cars, etc. A patient in our service refused to submit to operation, but was so seriously inconvenienced by the vibrations of the car which brought the meals that he finally begged for an operation. As a matter of fact, the first thing noticed by him after the cranioplasty was the disappearance of the trouble caused by the same wagon. A Chasseurs officer who resumed his service eight months after the operation, and who had previously been unable to ride in an auto- mobile, stated that the bursting of the shells now produced no cere- bral perturbation. There are in addition a series of small variable signs, according to different individuals, largely referable to disturbances resulting from loss of equilibrium in the pressure of the intracranial fluid, caused by the solution in continuity of the skull cap; these signs sub- side with the performance of cranioplasty. The advantage of restoring its uniformity of internal pressure to the brain, except in cases of over-pressure, is universally conceded. Our own experience leads us to the conclusion that cranioplasty causes the disappearance of all the principal signs of the trephine syndrome: the last to disappear is the vertigo. The headaches and muscular weakness observed in all patients with cranial lesions sub- side rapidly. The following detail illustrates the beneficial effects of cranio- plasty: Trephined patients are, as.a rule, unable to tolerate the “movies;” after cranioplasty they can follow the pictures on the film. The experience of two years does not yet permit the drawing of conclusions; these cases must be observed for a very long time; but rneanwhile. it may already be stated that a considerable number of patients are evidently benefited by the intervention. Before oper- ating upon them the cases must be carefully studied, refraining from interference when a contraindication exists. “All losses of substance, both small and large, must be closed by a graft. The contraindications are as follows: (1) Infection; (2) the presence of intracerebral foreign bodies; (3) hyper-pressure, even slight, with edema of the papilla; (4) irre- ducible cerebral hernia; (5) cases of lesion of the occipital region with visual disturbances: (6) cases of recurrent epilepsy which do not improve on prolonged rest in bed. Beside these cases there will 240 CARTILAGINOUS CRANIOPLASTIES. always be special cases in which physician and surgeon will agree as to the nonadvisability of intervention. . Concerning the best procedure for grafting, this may be ives at some time to come on the basis of several hundreds of cases. Personally and until the contrary has been established, we accord the preference to cartilage grafts. The employment of metal, ivory, dead bone, or celluloid plates can not be generalized. Except in a few fortunate cases, these plates are cast out at the end of a certain time, or they play the part of foreign bodies. There is no longer any doubt between dead and living grafts, the latter being preferable. It remains to determine if bone or rather cartilage should be grafted. Bone grafts involve several disadvantages: (1) Necessity of general anesthesia. (2) When the pediculated flap is taken from the neighboring bone, it must be cut with the chisel and mallet, which should be avoided in cranial surgery. (3) When the graft is taken from the tibia and the loss of cranial sub- stance is considerable, a single graft does not suffice. (4) Difficulty of shaping the grafts so as to follow the configuration of the skull. (5) Sometimes the bony graft does not fuse with the margin of the loss of substance and the result is the establishment of a pseudoarthrosis, moving like the keys of a piano. (6) After the graft has healed in, one can never tell when the growth will stop, and real proliferations may result, causing cerebral compression. (7) The raw surface of the grafted bone remains irregular, which is dis- advantageous, whether it be in contact with the dura mater or with the scalp. In a general way bony grafts may be applied in certain small losses of substance of the frontoparieta] region, when the dura mater is intact, the graft then playing the part of a lid or a cover. Cartilaginous grafts possess all the advantages of a living graft; they heal in with remarkable facility. At the end of a certain time they acquire the consistency of bone, although without becoming ossified. The graft may be cut as thin as necessary and it is pos- sible to shape it perfectly convex as adapted to the skull cap. There are two methods of grafting the cartilage: Morestin’s method, with a number of chips, and Gosset’s procedure, with a single plate. We have nothing to say on the value of Morestin’s method, as we have never used it, having utilized in all our cases the sa plate, according to Gosset. In a few instances we have found it necessary to fit two plates, on account of the great extent of the loss of substance; in other cases we have intentionally broken the plate, preserving the perichondrium intact, so as to make it less rigid. We have performed by this method 54 cases of simple cranioplasty and 3 cases of double cranioplasty, meaning that at the same session “uotsod ul usayed a4) YM eB ayy BululjyNO ‘eouvysqns jo sso] |eluBIo jo Uayed ‘(4e]Ue9)—s¢ ‘Bid PSS OOS ; , PEDRO FF 222A ATL 99 fp hTD “9A OW) OF Y~*PPIID® HY SP e1IS =x “FL srIEF ; 7 aa as Poe Ny 7 py So SSS SSS 240-1 *anbijqo jeuseyxe 'Z f8}s00 ey} Sulsewep ynouyM Junojsiq B YM o8e 34e9 WOdJ JJe4S BY} BulAsvo Jo pouye~i—'g “314 ‘SfosnlW snjoed WUsIY ‘, ulsaew CARTILAGINOUS CRANIOPLASTIES. 241 two cranial orifices were closed in the same patient. None of these cases were followed by disturbances referable to the intervention. All wounds healed by first intention, and there was no instance of elimination of the graft. The results obtained in the last 50 patients are superior to the first, on account of the improved technic of the operation. We were present at the first interventions of Prof. Gosset and obtained from him the general rules governing the operation. These rules especially have contributed to the improved results: (1) The local anesthesia; (2) the extreme thinness of the grafted plate; (8) the drainage during 48 hours, which guards against hem- atoma. As to the proper time for operating upon these patients, some sur- geons have tried to apply the graft immediately after trephining and extraction of foreign bodies; followed by complete closure of the wound. There is not yet a sufficient number of such cases to permit an estimate of this method. ° Personally we wait for the healing of the wound and the subsi- dence of the tissue obstruction to apply the graft; which means that the operation is performed as soon as the condition of the tissues permits. This serves to prevent the onset of some subjective symp- toms. OPERATION. Anesthésia—Barring a few rare exceptions, the operation is per- formed under local anesthesia. A morphine injection is given one hour before the operation; in case of very excitable patients or those subject to epileptic attacks, it is advisable to give the night before and a few hours preceding the operation an enema containing 1 gram of chloral and 1 gram of bromide. oo Novocain at 1 per cent with adrenalin is used. The scalp is in- filtrated over a large surface, but at some distance from the region to be operated on. In case of the temporal region, superficial and deep injections are made, so as to reach all the nerves. Anesthesia of the costal margin follows next. A long needle in- serted near the cartilage of the ninth rib and pushed in horizontally between the muscles and the cartilages following the direction of the costal margin as far as the level of the fifth or sixth cartilage, and a large amount is injected in order to insure a good deep anesthesia. Without completely withdrawing the needle, it is carried across the subcutaneous tissues which are abundantly infiltrated in the cus- tomary manner. The infiltrated costal margin forms a real “ ridge,” which promptly subsides because the large amount of regional connective tissue per- mits the absorption of the fluid. 242 CARTILAGINOUS CRANIOPLASTIES. Before beginning the operation, it is advisable to have an assistant hold the patient’s head, not only.to immobilize it, but especially to lend the patient a moral support and show him that he is not alone. This is a small practical detail which should not be overlooked. Intervention —The operation comprises two chief steps: (1) The preparation of the cranial gap; (2) the removal of the cartilaginous gratt. os Extirpation of the cicatriv on the scalp—The most common type is the crucial cicatrix; next, large irregular cicatrices are found; a horseshoe cicatrix is rare. The rule is to make no incision which would add a new cicatrix to those already present. In the cases of horseshoe cicatrix, one cuts through the old cicatrix and mobilizes the cutaneous flap as for tre- phining. When the cicatrix is very irregular, it is entirely extirpated, followed by the mobilization of one or several scalp flaps, as required for the plastic work. In cases of crucial cicatrix, the operator limits himself to extirpating the larger and more adherent branch, which is cut around by an ovaloid incision. Figure 1.—In all cases the extirpation of the cicatrix must be very cautiously done, because it is always necessary to leave a portion of the fibrous tissue which is to play the part of dura mater, and as there is no plane of cleavage, the deep aspect of the cicatrix must be carved with the bistoury. But one should not exaggerate and leave too much scar tissue. A few perforations of the dura mater or of the membrane which has replaced it permit the escape of some drops of cerebro-spinal fluid, but this has no untoward results. Figure 2—The cicatrix having been extirpated the lips of the wound are mobilized by some snips with the bistoury, cutting through the connective tissue which separates the scalp from the pericranium. The loss of substance appears in the wound. Detachment of the dura mater. Under the guidance of the finger an incision is applied in the pericranium at a distance of 1 or 2 millimeters from the border of the loss of bony substance. Utilizing the curved rugine of Fara- beuf as a scraper the circumscribed portion of the pericranium is de- tached and the bone exposed. Figure 3—With the same rugine, which is insinuated with one of its angles between the bone and the dura mater, the detachment of the dura mater is carried out on the entire circumference (Gosset). From this time on the cerebral pulsations become stronger. By means of a piece of cloth a pattern is made of the loss of substance to serve for the removal of the graft from the costal cartilages. (Usually ‘this pattern is cut out the evening before the operation by applying . the piece of cloth or paper directly over the loss of cranial substance, the finger serving as guide and radiography as control.) Temporary Gig. af bans Fig. 7.—The graft installed, 242-1 SSS = S = = SS S = = Se esses eS ——— SS Ss Se I Sikioe, he cede’ Cheer ha 2 Bil out rlace. Jrover 4h heures . 242-2 Fig, 8.—1, Suture of the hairy scalp; 2, drain left in for 48 hours CARTILAGINOUS CRANIOPLASTIES. 243 tamponing of the skull wound with compresses soaked in physio- logical salt solution. Next the costal margin is approached. Removal of the cartilaginous graft—For each of the cases we have ‘operated upon the left costal margin has been utilized. Incision of 8 to 12 centimeters on the anterior surface of the costal margin: Transverse division of the fibers of the anterior rectus and major oblique muscles. Figure 4.—Two strong separators permit the exposure of the costal cartilages. Next the model of the loss of substance is applied on the cartilages ; the size of the graft is outlined with the bistoury by an incision which follows the border of the pattern and takes in only the perichondrium (Gosset). Figure 5—The thickness of the graft must not exceed 2 milli- meters. To begin with, the bistoury is placed almost flatwise grazing the ribs; the cartilage is then freely incised, cutting with to-and-fro picpemiente As soon as possible the border of the graft is picked up with for- ceps and the incision is continued with the point of the bistoury, watching the cut surface so as to make the graft neither too thick nor too thin. Figure 6—The continuity of the costal margin is preserved and the loss of substance so trifling as compared to the thickness of the cartilage that two or even three layers can be removed without pro- ducing a solution of continuity of the cartilage. Temporary tamponing of the costal wound. The graft is carried to the skull. The perichondrium must be placed in contact with the dura mater. Before putting the graft in its place it is necessary to mold it by digital pressure so as to give it the shape of a watch glass. The border of the graft is slipped between dura mater and the skull. From this instant it ceases to move (Gosset). Figure 7—This method of fixing the graft has been criticized and regarded as capable of producing disturbances due to compression. Untoward results were never observed in our experience. The only objection against it is that it is not cosmetic in the sense that the graft lies deeper than the bones of the skull and that consequently after healing a depression is left at the site of the operation. We employ Gosset’s method only for losses of substance in the temporal bone; as the other bones are very thick, the graft is simply placed on the’ dura mater in contact with the bony border (diple). Above the graft a simple suture of the scalp is performed, leaving a small drain for 48 hours. This drainage is indispensable.—Perfect hemostasis of the oper- ative region is almost impossible and in the absence of drainage hematomas are observed between the scalp and the graft which some- 944 CARTILAGINOUS CRANIOPLASTIES. - times cause the elimination of the graft. In an autopsy case we were enabled to observe a hematoma which had detached the dura mater as far as the occipital foramen. Headaches, aphasia, a retarded pulse, somnolence, and nausea, which some operators have noted after grafting, are very often ref- erable to compression caused by the hematoma. None of these dis- turbances were observed in our patients. The repair of the costal gap is made in three layers—muscles, apo- neurosis, and skin. The sequelae are extremely simple. For a day or two the patient complains of pain at the level of the costal margin, never in the re- gion of the head. The drain is removed at the end of 48 hours and the threads at the end of 10 days. In very rare cases the cicatrix was of such dimensions that the entire surface of the cartilaginous graft could not be covered with scalp tissue; the portion of graft thus left bare continued to live, was not cast off, and became covered by proliferations until healing was complete. The patient gets up between the second and third week. The graft at this time gives the impression of being equally resistant as the skull, but repeated pressure during the examinations should be ° avoided. We were enabled to observe a patient 15 days after the operation, on whom a surgeon made a digital compression in order to ascertain if the graft was movable; this patient had so far had no Jacksonian attacks but had his. first after this examination and several others afterwards. As to the fate of the graft, we look back over an experience of slightly over two years. In none of these cases has it become absorbed; on the contrary, it hardens, thickens, and actually blends with the bones of the skull, but it remains transparent to.the X-rays. . Hint i h ty i Mt Hh ' AN 244 Fle. 9. TOPICAL INDEX. Page. Treatment of war wounds by the allies................0 ccc ce ceeeccecececeee ; 1 Wot aU bare: 3. ceeds oo rontccieties Hapalateewe's s Vee eeeevs peameucwwaie < 2 Ambrotse-Pares j.'s s'cinjeced 4 vs ebseseae oo ceidadsclacend onaaaeenades 2 Baron: Larrey.s sce 2 vassesewssececiatogac nc cacwbancdosies oluigenaaeck’s 2 Immediate, delayed, ‘and BOCONA ANY 522. eieisicieidceiediaicies'e's cadiastiow 4 Surg. Gen. Sir Anthony Bowlby...............0..02.ee cee ceeeeeeeee 4,5 Limitation of primary suture.................2.002006 Sonisbeamaaeislers 6 Statistics of surgical Automobile Ambulance No. 12.............- ere 7 Bar DY (8s /auieed's's 2 eds Sais Seas Muka ales aban ameeveew Si deseu ee 7 American Red Cross report.........-...-.02- saigistsGein o's Seseiceneey 8 Report: of Lemaitre acccecuyive . ousecenes = fi doeer wena bs dasameges eis 9 Carrel method: oJ 4021s sldadeede Cosaucews bsmese teenie ssadeeasaseen 10 Carrel-Dakin treatment... .... weet tenet cree ene rerreeeeeeee ~ 10 At Complegnes si eicicici sais os caaseawien aes Rat eaelennd ic dcuauedeeaee 10 At War Demonstration Hospital, New York..............2-2--ee0e0- 10,19 SAT SOISBODE caso ost pnaawiMee cistnoowiemioe sv Sepa Medd 2's tated 10 On U.S. 8. George Washington .........0.0 20 eee e cece eee e cence eeees ll Principle of application.................0.0.ce cece e cece eee eeecences 13 POCRNI QUO: ecieand & ca ualieeys wet hertel Gustave ain hyaua tale ina cual teataselsi ae 14 Preparation of Dakin solution............0.20-2e-ceeeeeeeceeneceees 17 Special apparatus for wounds of brain.............--+20+-seseeeee eee 18 ChUtrO nes joiceds sets syseatene Se on eee evs sue ee ted ys os eeeeeeeee 23 POZE eens sie linkin se evseeie caine oe eee aw e's SeE SEE SEES ee aeeneeaee 23 Corner...... wdsceeies o/s Geil dig Sizer efele aus Sieg walslove-eieloajzisiesecminig’e wie siemeciers aes 23 Bowlby and Wallace........... 22.2 --0- eee e cece cence eee e ee Bs ssc idiaiaedis 23 SipAlmroth Writht::.u.jcdcaqteedosecencet eats eckwcue sag beets zie 23 Sir Thomas Crisp: Mnglish «oo. 2... s:eisusie gis x vs slaisistei esgic ov eie'eisteeree oe 23 English and Kelly is... se0secesde iss anosedesestscwevexs eels seerasee 23 Dichloramine «5-22 eccsieie se bee esd shan Coes een eeeemm ses spas 24 OHIGTAMIN Paste saoseasceotiauccc nantes cue Saeiemiee Sines oe series 25 i Other methods. .....-2...-22--0022 eee eee pied Hoeeniatineses Vag uitins 26 Hypochlorous acid preparations, eusol and eupad...-.-.-..------- -- 26 Salt! packs oo 2c tcus sseedeee sas caine sade sey antewertlne + ciecipeees 29 Dichlotamiin il ooo. oc access teceisce eee se ohana essen wales ease sees eens 30 Magnesium sulphate. .......------- +222 e cece ee eee eee eee e ee eeee 31 Bipp..-..-- 2-22 e ee eee eee cee eee eee tence ence neneee » 31 Flavine x. i. sagen en eee was cee edie e o's iceecnkee ead poneine 32 Crystal violet and brilliant green.....-..-..-----+-+--+eeeee eee tees 35 Hypertonic solution.......---.----- +2122 cece scene cee eee ee ee ce eee te 35 Wright’s formula........-.----- 2202 cece ee cee ence eee eee e eer ce ne eee 36 Sunlight treatment... ....----.-------2-eeeee eee reeee ee tea eee ee ee 37 Artificial light........--.--.-- ete e nee een neers en enaeeenerennccrees 38 Phenolization and embalmment.........-.--------+-e-eee seer renee 38 Blectricity .-..-..--..--00- eee eec eee cee nec eee cece enon eceneeregecese 39 Oxygen and ozone. ..----- +--+ 222 eee e eet e reece eee e reese tteeces 40 246 TOPICAL INDEX. Page. Treatment of war wounds by the Germans...... Stara aats BP css anette hays yee i 43 Conditions in Germany late in 1915. ...-..2...- 2.0202 e eee eee eee eee 44 Hospitalat: Buel... 2%..002 223 samppedeee eda cnemeted oes Ps cen ened ean 44 Continuous baths..........---.-2--1 202-222 eee eee eee eee eee eee eee ees 44 VaCCiNGS 2.2 Si dsweyccancsietk tons aise 1a eeiabinie Reed obasaseecdeceices 45 « Physico-therapeuties ..c.0:. s.. dcseese es see ieee cee eee aiid wie eel oes 45 Wound treatments seca :osg eciusicetue ss poe scien oe eg ndeeeeearsese ess 46 Antiseptic solutions....0...+ 52 s2ex0esade soa deed cae ee es veeedeweeee ss s3 47 INTL ORC RIO-asaas aceepeSiasks: fe OSes ep SS SE WSS SES 2 EISEN ERO EE 48 MSCODILOSE a4: i anoeaeads te ai omieuiia ence joes Ls ohio cae 48 Work at a German base hospital in 1916............-.-----++---.----++- 48 Developments in war surgery........--.--- 2-22-2222 22 eee eee eee eee 51 ; Anesthesia ascgca.cen S20 cee eee ahaw od se cutee es a aie eee 51 Vocal nce caeeies Seley’ isla endless ee wl oa nuelsoles sea eggaier s < aton 51 Gas and Ox ygetl..2 jesq esses seeeseced sev ecumeeeiak ses ecasmeeeeeess + 51 American Red Cross apparatus........--.----. 2-20-22 e ee eee eee ee eee 52 Ona cag crane Sah Neptsrs 22 Shiga Sot iel tah eS eae a Ne ahaa Seas ane 53 GWathMeyo.c.i.¢.ccceusind satwonminetet ed cremeceuntod cates nee eans 54 Marshals avin cen toseeeahnasige hic vets see dewacwk eke esioesn eee ees 55 Spinal goo a 8 a S ro uF cYFLYVNo [ee epee <8 qB /SYILGIC : 1 il x 4 zs ; } eee co a | a ef is (Ri te ee é 5 Heme) ae (ieee ||) Gace |e = i a i! c uy re " O° rt u my ' 8 7 Yl) oe ee x = oe) t 9 ' s ' 3 yt 9 1 a t a ‘i . oy = ' 8 1 to wn 8 ; Ciel ate ' I ee i} i ' rt it t ' : ' i 3 ey ' : ' beste) oaal eee ise a 2 / 1 t Oy Suday Puccaug ea ot ered rome Sey 10M puo wuoydraray é ~sQ] Kron shy ‘peoey \ — ‘No neve USD Vv * Ng —